LOCUS       DADLIO010000001       148073 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.001, whole genome shotgun sequence.
ACCESSION   DADLIO010000001 DADLIO010000000
VERSION     DADLIO010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 148073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 148073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..148073
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.001"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(27..1523)
                     /gene="lysS"
                     /locus_tag="JOX41_000001"
     CDS             complement(27..1523)
                     /gene="lysS"
                     /locus_tag="JOX41_000001"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HAY6447779.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1634..2638)
                     /gene="dusB"
                     /locus_tag="JOX41_000002"
     CDS             complement(1634..2638)
                     /gene="dusB"
                     /locus_tag="JOX41_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HAY6447780.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2639..3526)
                     /gene="hslO"
                     /locus_tag="JOX41_000003"
     CDS             complement(2639..3526)
                     /gene="hslO"
                     /locus_tag="JOX41_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HAY6447781.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3743..5854)
                     /gene="hflB"
                     /locus_tag="JOX41_000004"
     CDS             complement(3743..5854)
                     /gene="hflB"
                     /locus_tag="JOX41_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HAY6447782.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5944..6489)
                     /gene="hpt"
                     /locus_tag="JOX41_000005"
     CDS             complement(5944..6489)
                     /gene="hpt"
                     /locus_tag="JOX41_000005"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HAY6447783.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6489..7934)
                     /gene="tilS"
                     /locus_tag="JOX41_000006"
     CDS             complement(6489..7934)
                     /gene="tilS"
                     /locus_tag="JOX41_000006"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HAY6447784.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8054..8524)
                     /locus_tag="JOX41_000007"
     CDS             complement(8054..8524)
                     /locus_tag="JOX41_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HAY6447785.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8570..8995)
                     /locus_tag="JOX41_000008"
     CDS             complement(8570..8995)
                     /locus_tag="JOX41_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HAY6447786.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9062..9331)
                     /locus_tag="JOX41_000009"
     CDS             complement(9062..9331)
                     /locus_tag="JOX41_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HAY6447787.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9342..10937)
                     /locus_tag="JOX41_000010"
     CDS             complement(9342..10937)
                     /locus_tag="JOX41_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAY6447788.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10952..14473)
                     /gene="mfd"
                     /locus_tag="JOX41_000011"
     CDS             complement(10952..14473)
                     /gene="mfd"
                     /locus_tag="JOX41_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HAY6447789.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14490..15050)
                     /locus_tag="JOX41_000012"
     CDS             complement(14490..15050)
                     /locus_tag="JOX41_000012"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HAY6447790.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15403..16377
                     /locus_tag="JOX41_000013"
     CDS             15403..16377
                     /locus_tag="JOX41_000013"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HAY6447791.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16547..17947
                     /locus_tag="JOX41_000014"
     CDS             16547..17947
                     /locus_tag="JOX41_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HAY6447792.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18025..18747)
                     /locus_tag="JOX41_000015"
     CDS             complement(18025..18747)
                     /locus_tag="JOX41_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAY6447793.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18826..19332)
                     /locus_tag="JOX41_000016"
     CDS             complement(18826..19332)
                     /locus_tag="JOX41_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAY6447794.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSINHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19455..21254
                     /locus_tag="JOX41_000017"
     CDS             19455..21254
                     /locus_tag="JOX41_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HAY6447795.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21322..22932)
                     /locus_tag="JOX41_000018"
     CDS             complement(21322..22932)
                     /locus_tag="JOX41_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6447796.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTG
                     SSTPAPTPTPTPEQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCS
                     GFTRYVYMQVTGRDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGG
                     QYIHAPQPGESVKVGSVQWFAPDFAVSM"
     gene            complement(23187..23696)
                     /gene="mreD"
                     /locus_tag="JOX41_000019"
     CDS             complement(23187..23696)
                     /gene="mreD"
                     /locus_tag="JOX41_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HAY6447797.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23700..24554)
                     /gene="mreC"
                     /locus_tag="JOX41_000020"
     CDS             complement(23700..24554)
                     /gene="mreC"
                     /locus_tag="JOX41_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HAY6447798.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24709..25347)
                     /locus_tag="JOX41_000021"
     CDS             complement(24709..25347)
                     /locus_tag="JOX41_000021"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HAY6447799.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25348..25998)
                     /locus_tag="JOX41_000022"
     CDS             complement(25348..25998)
                     /locus_tag="JOX41_000022"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HAY6447800.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGRFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(26011..26910)
                     /gene="rsgA"
                     /locus_tag="JOX41_000023"
     CDS             complement(26011..26910)
                     /gene="rsgA"
                     /locus_tag="JOX41_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HAY6447801.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27075..29144)
                     /gene="pknB"
                     /locus_tag="JOX41_000024"
     CDS             complement(27075..29144)
                     /gene="pknB"
                     /locus_tag="JOX41_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HAY6447802.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29141..29881)
                     /locus_tag="JOX41_000025"
     CDS             complement(29141..29881)
                     /locus_tag="JOX41_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HAY6447803.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(29894..31252)
                     /gene="rsmB"
                     /locus_tag="JOX41_000026"
     CDS             complement(29894..31252)
                     /gene="rsmB"
                     /locus_tag="JOX41_000026"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HAY6447804.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKMLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31252..32190)
                     /locus_tag="JOX41_000027"
     CDS             complement(31252..32190)
                     /locus_tag="JOX41_000027"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HAY6447805.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKKAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32183..32674)
                     /gene="def"
                     /locus_tag="JOX41_000028"
     CDS             complement(32183..32674)
                     /gene="def"
                     /locus_tag="JOX41_000028"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAY6447806.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32689..35097)
                     /gene="priA"
                     /locus_tag="JOX41_000029"
     CDS             complement(32689..35097)
                     /gene="priA"
                     /locus_tag="JOX41_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HAY6447807.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35350..35655)
                     /locus_tag="JOX41_000030"
     CDS             complement(35350..35655)
                     /locus_tag="JOX41_000030"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAY6447808.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35660..36274)
                     /gene="gmk"
                     /locus_tag="JOX41_000031"
     CDS             complement(35660..36274)
                     /gene="gmk"
                     /locus_tag="JOX41_000031"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HAY6447809.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEKRMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            complement(36761..37045)
                     /locus_tag="JOX41_000032"
     CDS             complement(36761..37045)
                     /locus_tag="JOX41_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6447810.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(37063..37953)
                     /locus_tag="JOX41_000033"
     CDS             complement(37063..37953)
                     /locus_tag="JOX41_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HAY6447811.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFVLDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(37973..38191)
                     /locus_tag="JOX41_000034"
     CDS             complement(37973..38191)
                     /locus_tag="JOX41_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6447812.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(38161..39861)
                     /locus_tag="JOX41_000035"
     CDS             complement(38161..39861)
                     /locus_tag="JOX41_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HAY6447813.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            40128..40901
                     /locus_tag="JOX41_000036"
     CDS             40128..40901
                     /locus_tag="JOX41_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6447814.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(40982..41551)
                     /gene="thiT"
                     /locus_tag="JOX41_000037"
     CDS             complement(40982..41551)
                     /gene="thiT"
                     /locus_tag="JOX41_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HAY6447815.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(41617..41719)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(41725..42696)
                     /locus_tag="JOX41_000038"
     CDS             complement(41725..42696)
                     /locus_tag="JOX41_000038"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HAY6447816.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(42790..44163)
                     /gene="glmU"
                     /locus_tag="JOX41_000039"
     CDS             complement(42790..44163)
                     /gene="glmU"
                     /locus_tag="JOX41_000039"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HAY6447817.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(44666..45484)
                     /gene="purR"
                     /locus_tag="JOX41_000040"
     CDS             complement(44666..45484)
                     /gene="purR"
                     /locus_tag="JOX41_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HAY6447818.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(45651..46475)
                     /locus_tag="JOX41_000041"
     CDS             complement(45651..46475)
                     /locus_tag="JOX41_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAY6447819.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(46448..47128)
                     /locus_tag="JOX41_000042"
     CDS             complement(46448..47128)
                     /locus_tag="JOX41_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAY6447820.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(47151..48089)
                     /locus_tag="JOX41_000043"
     CDS             complement(47151..48089)
                     /locus_tag="JOX41_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HAY6447821.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(48334..49185)
                     /locus_tag="JOX41_000044"
     CDS             complement(48334..49185)
                     /locus_tag="JOX41_000044"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HAY6447822.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            complement(49339..51912)
                     /gene="mprF"
                     /locus_tag="JOX41_000045"
     CDS             complement(49339..51912)
                     /gene="mprF"
                     /locus_tag="JOX41_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HAY6447823.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            52053..52859
                     /gene="proC"
                     /locus_tag="JOX41_000046"
     CDS             52053..52859
                     /gene="proC"
                     /locus_tag="JOX41_000046"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HAY6447824.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLIDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(52938..54494)
                     /gene="rny"
                     /locus_tag="JOX41_000047"
     CDS             complement(52938..54494)
                     /gene="rny"
                     /locus_tag="JOX41_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HAY6447825.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(54905..55954)
                     /gene="recA"
                     /locus_tag="JOX41_000048"
     CDS             complement(54905..55954)
                     /gene="recA"
                     /locus_tag="JOX41_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HAY6447826.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFANPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(56063..57304)
                     /locus_tag="JOX41_000049"
     CDS             complement(56063..57304)
                     /locus_tag="JOX41_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HAY6447827.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(57544..58122)
                     /gene="pgsA"
                     /locus_tag="JOX41_000050"
     CDS             complement(57544..58122)
                     /gene="pgsA"
                     /locus_tag="JOX41_000050"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HAY6447828.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(58331..59215)
                     /locus_tag="JOX41_000051"
     CDS             complement(58331..59215)
                     /locus_tag="JOX41_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAY6447829.1"
                     /translation="MAFETIGEKLRQARLNKKISLDELQQITKIQKRYLEAIDNDDFD
                     QLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQPETVSTSRKAMHQ
                     EESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDTASSLKVEGSVEES
                     SSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITDATKPVTLEFTAVN
                     RVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNATIKANGESVPVNP
                     GENNQSPKNVNLTLQYAE"
     gene            complement(59993..61279)
                     /locus_tag="JOX41_000052"
     CDS             complement(59993..61279)
                     /locus_tag="JOX41_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAY6447830.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(61272..62540)
                     /locus_tag="JOX41_000053"
     CDS             complement(61272..62540)
                     /locus_tag="JOX41_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAY6447831.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            62792..63253
                     /gene="mscL"
                     /locus_tag="JOX41_000054"
     CDS             62792..63253
                     /gene="mscL"
                     /locus_tag="JOX41_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HAY6447832.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(63312..63758)
                     /locus_tag="JOX41_000055"
     CDS             complement(63312..63758)
                     /locus_tag="JOX41_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAY6447833.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGE
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(63851..64096)
                     /locus_tag="JOX41_000056"
     CDS             complement(63851..64096)
                     /locus_tag="JOX41_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6447834.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(64211..64789)
                     /locus_tag="JOX41_000057"
     CDS             complement(64211..64789)
                     /locus_tag="JOX41_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAY6447835.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(64866..65396)
                     /locus_tag="JOX41_000058"
     CDS             complement(64866..65396)
                     /locus_tag="JOX41_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HAY6447836.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(65400..66260)
                     /gene="rlmB"
                     /locus_tag="JOX41_000059"
     CDS             complement(65400..66260)
                     /gene="rlmB"
                     /locus_tag="JOX41_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HAY6447837.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(66253..66648)
                     /locus_tag="JOX41_000060"
     CDS             complement(66253..66648)
                     /locus_tag="JOX41_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HAY6447838.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(66645..68057)
                     /locus_tag="JOX41_000061"
     CDS             complement(66645..68057)
                     /locus_tag="JOX41_000061"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HAY6447839.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(68054..68590)
                     /gene="cysE"
                     /locus_tag="JOX41_000062"
     CDS             complement(68054..68590)
                     /gene="cysE"
                     /locus_tag="JOX41_000062"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HAY6447840.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     gene            complement(68912..70372)
                     /locus_tag="JOX41_000063"
     CDS             complement(68912..70372)
                     /locus_tag="JOX41_000063"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HAY6447841.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(70542..71699)
                     /locus_tag="JOX41_000064"
     CDS             complement(70542..71699)
                     /locus_tag="JOX41_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HAY6447842.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(71733..73103)
                     /gene="radA"
                     /locus_tag="JOX41_000065"
     CDS             complement(71733..73103)
                     /gene="radA"
                     /locus_tag="JOX41_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HAY6447843.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKTAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(73166..73693)
                     /locus_tag="JOX41_000066"
     CDS             complement(73166..73693)
                     /locus_tag="JOX41_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HAY6447844.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            73923..74729
                     /gene="proB"
                     /locus_tag="JOX41_000067"
     CDS             73923..74729
                     /gene="proB"
                     /locus_tag="JOX41_000067"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HAY6447845.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            74726..75973
                     /locus_tag="JOX41_000068"
     CDS             74726..75973
                     /locus_tag="JOX41_000068"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HAY6447846.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            76049..76393
                     /locus_tag="JOX41_000069"
     CDS             76049..76393
                     /locus_tag="JOX41_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6447847.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(76510..76836)
                     /locus_tag="JOX41_000070"
     CDS             complement(76510..76836)
                     /locus_tag="JOX41_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6447848.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(77451..78653)
                     /locus_tag="JOX41_000071"
     CDS             complement(77451..78653)
                     /locus_tag="JOX41_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAY6447849.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            78770..79285
                     /locus_tag="JOX41_000072"
     CDS             78770..79285
                     /locus_tag="JOX41_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAY6447850.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(79484..79930)
                     /locus_tag="JOX41_000073"
     CDS             complement(79484..79930)
                     /locus_tag="JOX41_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HAY6447851.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(79977..81455)
                     /gene="msr"
                     /locus_tag="JOX41_000074"
     CDS             complement(79977..81455)
                     /gene="msr"
                     /locus_tag="JOX41_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Msr family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAY6447852.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(81809..82438)
                     /locus_tag="JOX41_000075"
     CDS             complement(81809..82438)
                     /locus_tag="JOX41_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAY6447853.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            complement(82422..82886)
                     /locus_tag="JOX41_000076"
     CDS             complement(82422..82886)
                     /locus_tag="JOX41_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAY6447854.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(83373..84641)
                     /locus_tag="JOX41_000077"
     CDS             complement(83373..84641)
                     /locus_tag="JOX41_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosaminidase"
                     /protein_id="HAY6447855.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(84872..85609)
                     /locus_tag="JOX41_000078"
     CDS             complement(84872..85609)
                     /locus_tag="JOX41_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAY6447856.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(85676..86245)
                     /locus_tag="JOX41_000079"
     CDS             complement(85676..86245)
                     /locus_tag="JOX41_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HAY6447857.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            86373..87245
                     /locus_tag="JOX41_000080"
     CDS             86373..87245
                     /locus_tag="JOX41_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAY6447858.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            87587..88459
                     /locus_tag="JOX41_000081"
     CDS             87587..88459
                     /locus_tag="JOX41_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAY6447859.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            88456..90414
                     /locus_tag="JOX41_000082"
     CDS             88456..90414
                     /locus_tag="JOX41_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAY6447860.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(90746..91597)
                     /locus_tag="JOX41_000083"
     CDS             complement(90746..91597)
                     /locus_tag="JOX41_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAY6447861.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWVLKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            91720..92187
                     /locus_tag="JOX41_000084"
     CDS             91720..92187
                     /locus_tag="JOX41_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HAY6447862.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(92450..92932)
                     /locus_tag="JOX41_000085"
     CDS             complement(92450..92932)
                     /locus_tag="JOX41_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAY6447863.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(93032..93895)
                     /locus_tag="JOX41_000086"
     CDS             complement(93032..93895)
                     /locus_tag="JOX41_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAY6447864.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            94493..95368
                     /locus_tag="JOX41_000087"
     CDS             94493..95368
                     /locus_tag="JOX41_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6447865.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
     gene            complement(95513..95665)
                     /locus_tag="JOX41_000088"
                     /pseudo
     CDS             complement(95513..95665)
                     /locus_tag="JOX41_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(95933..97264)
                     /locus_tag="JOX41_000089"
     CDS             complement(95933..97264)
                     /locus_tag="JOX41_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAY6447866.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFALLSFIIIQLF
                     NMDINKLITTIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDPFLIQN
                     MQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKDFAKLS
                     VTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVVQIPWT
                     TPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
     gene            complement(97413..98126)
                     /locus_tag="JOX41_000090"
     CDS             complement(97413..98126)
                     /locus_tag="JOX41_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAY6447867.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            98301..99725
                     /locus_tag="JOX41_000091"
     CDS             98301..99725
                     /locus_tag="JOX41_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015508962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAY6447868.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            100024..100731
                     /locus_tag="JOX41_000092"
     CDS             100024..100731
                     /locus_tag="JOX41_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HAY6447869.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            100718..101041
                     /locus_tag="JOX41_000093"
     CDS             100718..101041
                     /locus_tag="JOX41_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HAY6447870.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(101130..102167)
                     /locus_tag="JOX41_000094"
     CDS             complement(101130..102167)
                     /locus_tag="JOX41_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HAY6447871.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHIL
                     GKVVVSGPFNG"
     gene            complement(102488..103471)
                     /locus_tag="JOX41_000095"
     CDS             complement(102488..103471)
                     /locus_tag="JOX41_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HAY6447872.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            complement(103886..104656)
                     /locus_tag="JOX41_000096"
     CDS             complement(103886..104656)
                     /locus_tag="JOX41_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAY6447873.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(104649..105584)
                     /locus_tag="JOX41_000097"
     CDS             complement(104649..105584)
                     /locus_tag="JOX41_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6447874.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(105900..107549)
                     /locus_tag="JOX41_000098"
     CDS             complement(105900..107549)
                     /locus_tag="JOX41_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAY6447875.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            complement(107666..110269)
                     /locus_tag="JOX41_000099"
     CDS             complement(107666..110269)
                     /locus_tag="JOX41_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAY6447876.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            complement(110281..111330)
                     /locus_tag="JOX41_000100"
     CDS             complement(110281..111330)
                     /locus_tag="JOX41_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HAY6447877.1"
                     /translation="MEFKKQGREILNHFQSGVSYMIPLVVAAGLLTSIAVIFGGTGVW
                     DQTDTFWGVLRMIGQTGLQFIVPMISAYIAYSIADRPGLAPAFITGMMCQNLGMGFIG
                     GMVAGLACGYLANALKKVKVPMQVISLKSIMLIPFVTTLVVGIILWYVLATPIQAMTT
                     GLTNWLEGMSGANAALMSAILGGMMAFDMGGPINKIAYAFGVASFSSGSFGPSTAMLL
                     GIAIPPFGMFLATILNKKLYDESERDNAKTAMIMGLVGITEGTIPFAVKDPLRVIPSI
                     VVGTAVACGLNGFFGVTQETMLSTFMAIPFVTNIPLYLVSIVIGGVVTALMVNALKSI
                     KYKKEQQVNSVEEGK"
     gene            complement(111356..111670)
                     /locus_tag="JOX41_000101"
     CDS             complement(111356..111670)
                     /locus_tag="JOX41_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HAY6447878.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            complement(111686..112132)
                     /locus_tag="JOX41_000102"
     CDS             complement(111686..112132)
                     /locus_tag="JOX41_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAY6447879.1"
                     /translation="MISEKININNIVIDLNASDKKSVVEKLSKLLETNGFVSDHKQFQ
                     KDVFDRENHMTTGIGKNIAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLL
                     AIKDTDKGTNHLRILAELSGRLMDDEFVKRIKDSRNKKELVKALSF"
     gene            complement(112133..114109)
                     /locus_tag="JOX41_000103"
     CDS             complement(112133..114109)
                     /locus_tag="JOX41_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HAY6447880.1"
                     /translation="MKIEIIIVHLSCIQEVKIMGIEFSERQMKILYFLIENEHTTYKE
                     LSEQLYVSTKTISKDILILKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKIN
                     IADSPEDRLTYVFAKLLNTNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLV
                     SDRNGVRIKADEKSKRRLMSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDI
                     LKKVAELLNRYMNKTQLKFTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNT
                     LILIKMIEKAFSIIVPIDEQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVR
                     IKLNEFYPDEELINNLVLHLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEE
                     IEERFCIHFNEDEIAYVTLHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFA
                     DMVEIEDVLSINELQDRKVTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQL
                     NEQTEDAFLNLLDKRFCFFTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKL
                     SSTAMNDFAMPHIEVDFIKKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKI
                     YETFNEIASNHELLANLKTSSSFEKLVYILKEGL"
     gene            complement(114267..115163)
                     /locus_tag="JOX41_000104"
     CDS             complement(114267..115163)
                     /locus_tag="JOX41_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAY6447881.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(115156..115836)
                     /locus_tag="JOX41_000105"
     CDS             complement(115156..115836)
                     /locus_tag="JOX41_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAY6447882.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(115837..116619)
                     /locus_tag="JOX41_000106"
     CDS             complement(115837..116619)
                     /locus_tag="JOX41_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAY6447883.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(116612..117529)
                     /locus_tag="JOX41_000107"
     CDS             complement(116612..117529)
                     /locus_tag="JOX41_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAY6447884.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(117693..118016)
                     /locus_tag="JOX41_000108"
     CDS             complement(117693..118016)
                     /locus_tag="JOX41_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAY6447885.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWKTTQPRLRDSLIFLGGSLAIVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEK
                     KESGN"
     gene            118804..122031
                     /gene="fss3"
                     /locus_tag="JOX41_000109"
     CDS             118804..122031
                     /gene="fss3"
                     /locus_tag="JOX41_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HAY6447886.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVAPVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            122144..122458
                     /locus_tag="JOX41_000110"
     CDS             122144..122458
                     /locus_tag="JOX41_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAY6447887.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            122471..122845
                     /locus_tag="JOX41_000111"
     CDS             122471..122845
                     /locus_tag="JOX41_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAY6447888.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            122855..123190
                     /locus_tag="JOX41_000112"
     CDS             122855..123190
                     /locus_tag="JOX41_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HAY6447889.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            123273..124613
                     /locus_tag="JOX41_000113"
     CDS             123273..124613
                     /locus_tag="JOX41_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010759325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HAY6447890.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKICYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            124691..125365
                     /locus_tag="JOX41_000114"
     CDS             124691..125365
                     /locus_tag="JOX41_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAY6447891.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            125598..126032
                     /gene="dcm"
                     /locus_tag="JOX41_000115"
     CDS             125598..126032
                     /gene="dcm"
                     /locus_tag="JOX41_000115"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HAY6447892.1"
                     /translation="MRFLDLFAGIGGFRLGMEQASHHCIGFCEIDKFARRSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQRFSDTRGTLFFEIARF
                     TTLLRPKLLFLENVRGLLNHEGGATFETILRTLDGLGYDVEW"
     gene            126033..126740
                     /locus_tag="JOX41_000116"
     CDS             126033..126740
                     /locus_tag="JOX41_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HAY6447893.1"
                     /translation="MLNSKAYIPQSRERIFLIGHSRDACTEQVFPIIGPSSTSDQNIR
                     NLVNINPSNRGMGGQVYGSDGVAPTLTGDEGIKIALPARDGISVAGLLPGKFEQGNRV
                     YEVTGTAPTLSTKQGGTKIMIRKNETEYQEVKPEDSVNLAFPNSTSRRGRLGKQSVHT
                     LLTGDQQAIVTDQYQIRKLTPRECWRLQGFPDWAFDRDSQVNSDSQLYKQAGNSVTVP
                     VIFDIARRLKELDVHGL"
     gene            126730..127020
                     /locus_tag="JOX41_000117"
     CDS             126730..127020
                     /locus_tag="JOX41_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6447894.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            127279..128463
                     /locus_tag="JOX41_000118"
     CDS             127279..128463
                     /locus_tag="JOX41_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAY6447895.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            128478..128597
                     /locus_tag="JOX41_000119"
     CDS             128478..128597
                     /locus_tag="JOX41_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HAY6447896.1"
                     /translation="MGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKGK"
     gene            129343..131253
                     /gene="ltrA"
                     /locus_tag="JOX41_000120"
     CDS             129343..131253
                     /gene="ltrA"
                     /locus_tag="JOX41_000120"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAY6447897.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            131357..131581
                     /locus_tag="JOX41_000121"
     CDS             131357..131581
                     /locus_tag="JOX41_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6447898.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLSLFNRIVGA"
     gene            131594..132097
                     /locus_tag="JOX41_000122"
     CDS             131594..132097
                     /locus_tag="JOX41_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAY6447899.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            132157..132546
                     /locus_tag="JOX41_000123"
     CDS             132157..132546
                     /locus_tag="JOX41_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAY6447900.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            132533..134980
                     /locus_tag="JOX41_000124"
     CDS             132533..134980
                     /locus_tag="JOX41_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAY6447901.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKDSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            134985..137108
                     /locus_tag="JOX41_000125"
     CDS             134985..137108
                     /locus_tag="JOX41_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAY6447902.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            137105..138109
                     /locus_tag="JOX41_000126"
     CDS             137105..138109
                     /locus_tag="JOX41_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
                     /protein_id="HAY6447903.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            138128..139039
                     /locus_tag="JOX41_000127"
     CDS             138128..139039
                     /locus_tag="JOX41_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAY6447904.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            139226..139482
                     /locus_tag="JOX41_000128"
                     /pseudo
     CDS             139226..139482
                     /locus_tag="JOX41_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(139699..139914)
                     /locus_tag="JOX41_000129"
     CDS             complement(139699..139914)
                     /locus_tag="JOX41_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6447905.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(140163..140381)
                     /locus_tag="JOX41_000130"
                     /pseudo
     CDS             complement(140163..140381)
                     /locus_tag="JOX41_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174271.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(140676..142115)
                     /locus_tag="JOX41_000131"
     CDS             complement(140676..142115)
                     /locus_tag="JOX41_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAY6447906.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            complement(142703..143335)
                     /locus_tag="JOX41_000132"
     CDS             complement(142703..143335)
                     /locus_tag="JOX41_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HAY6447907.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            complement(143684..145135)
                     /locus_tag="JOX41_000133"
     CDS             complement(143684..145135)
                     /locus_tag="JOX41_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HAY6447908.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSTESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            complement(145247..146590)
                     /locus_tag="JOX41_000134"
     CDS             complement(145247..146590)
                     /locus_tag="JOX41_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAY6447909.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            complement(146724..>148073)
                     /locus_tag="JOX41_000135"
     CDS             complement(146724..>148073)
                     /locus_tag="JOX41_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAY6447910.1"
                     /translation="TNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDT
                     VKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNVTNLPALPEGTTVTDVTPGGT
                     IDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKYNPEGQKVTTDLNKEPDA
                     SEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSSDEVEVDVTVTDTRSD
                     ADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGTVVVT
                     YPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTVTLPDGSQHHG
                     TADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNKKDSGKNGSKGSKTD
                     NQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGTLGLLGYKNRKKENE"
BASE COUNT        43225 a        30423 c        26873 g        47552 t
ORIGIN      
        1 gaattcctta gacagctttt attcgattat ctcattgttg ggaatagcaa aacatcccga
       61 attgattgtg catcagttag caacattact aatctgtcga tcccgatgcc tagaccacca
      121 gttggcggca taccgtattc taaggcttcc aagaagtctt cgtctacacc gtgagcttcg
      181 tcatttccta gttcacgttc tttttcttgc gcttcgaatc tttctctttg atcaattgga
      241 tcgttcagtt ctgtaaaggc attagcaaat tcgcgcccca ctatgaatag ttcgaatcga
      301 tctgtgaatc gaggatcttc tggatttttc ttcgctaaag gcgaaacttc gactggatgt
      361 ccgtatacaa acgtcggttg tgtcaatgtt tcttcaacaa atgtttcaaa gaattcattg
      421 ataacatgtc cgacacccat agcttcggtt acttctacat tgtgtttttc ggctaaagct
      481 aatgcttctt ccaatgtcat ttcttgccag aagtctacac cagtttgttc tttgattgca
      541 tctaccatat ggatgcgttt aaagtcactt tctaagtcga cagcttgtcc atcatatgtg
      601 atttttgctg ttcctagtac tttttcagct gcgttacgga taataccttc tgtcagattc
      661 attacatcat tgaaatcagt atatgctgtg tatgcttcta acatcgtaaa ttctggatta
      721 tgtgtagtat caattccttc attacggaaa acgcggccga tttcataaac tttttccatt
      781 ccgccaacaa ttagtcgttt taaatgaagt tctagcgcaa tacgcaaata taaatcaatg
      841 tccagtgcat tatgatgcgt gataaatggg cgtgcggcag ctccacctgc ctcattgtgc
      901 aatactggtg tttctacttc aatatagcca ttgccatcta aatagcgacg gatttcgctg
      961 ataatttggc ttcgtttcat aaatcggtca aagctttcgc gattactgat taaatccaag
     1021 tagcgttgtc tgtagcgttg ttcaatattc gttaagccat ggtatttatc tggcagtgga
     1081 cgaagtgctt ttgacaaaat cgtgatttct gaagctttga tagaaacttc gcctgtgtct
     1141 gttttcatga tttgtccagt tacaccaaag aaatctccaa ggtctgcatg tttgaatact
     1201 tcataggcct catcacctac ttggtctttt cttacataaa tttgaatttg gccttcacga
     1261 tcttgtagat gcgcaaatcc agctttccct tttcctcggc gagtcatcat acgaccagct
     1321 acactagcgg tcaatcccat ttctgctagt tcttcttttg ttcttggatc aaatagttca
     1381 tgcaattctt ctgagttgtg cgtgcgttca aatcgttttc caaatggatc gattccatct
     1441 tcacgcaatt gttccatttt ttgacgacgt acaagcattt gatcatttaa atcttctact
     1501 tgatgttgtt gttcctgtgt cacaaaagtt cctccattct catgttaatc tctttcctat
     1561 aatgccaatg aaacacaaaa aaagcaagcc gaacttggaa tttcggcttg aaaattcacg
     1621 aaaaacttag aaatcacaac gtttgtttca atagtacttt ttccgctttt tctacaaatt
     1681 gatccagcag gtcattgatt tcttgctgtt tttctgtctg attgattgct actttcactt
     1741 tcgctgctcg aggaatccct tttaaataat aagccgcatg tgttctgaat tctctacaag
     1801 ctactttttc tcctttgaga tctgctaagc gttgtaaatg aagtttagct gtagcaattt
     1861 tttcggctgg tgttggttca ggaatcagtt cccctgtttc gagataatgc tgtgtgcggt
     1921 gaatcatcca tggattgccc agcgctgcac gaccaatcat cacaccgtct gcaccgacat
     1981 agtcaagcat ccattttgca tcttctggcg ttttgacatc cccgttcccc ataaatggaa
     2041 tcgtcaaatg ttttttcact tctttcaata cttcccagtc cgcttttcct tcatacatct
     2101 gaacccgtgt acgtccatgc atagcgatgg cacttgctcc agctgattgt gctgctaatg
     2161 cattttctac agcaaagacg tgctcttcat cccaaccaat acgcatcttg attgttactg
     2221 ggatatttac tgctgaagaa acagcttgga ccatttcgta tactttctca ggatctaaaa
     2281 gccattttgc tcctgcttct gctttgatta ctttatttac tggacagccc atattgatat
     2341 ctattatatc ggcagctgtg ttttcttcga caaattgagc agcttcaact agactatctt
     2401 tatttccgcc aaatatctgt aaacttaatg gatgttctgt ttcttcaatg tggagcatct
     2461 ctaaagtttt tttgtttctg aaatgaatac cttggtcact gatcatttca catacgacta
     2521 agcccgcacc aaattctttg acagtgactc gaaatgctga atttgttatt ccagccatcg
     2581 gtgcaacaac gacacgatta gggatttcca cattgccaat tttccatgtg tgttccactt
     2641 aaatccctcc taaggcttct ttcttcaatc catctaattc ttcttcgcta tacttgtatt
     2701 tgttattaca gaaagaacaa accgcttctg caccgtgatc ttcgtctatc attgcttgga
     2761 tttcttctgc acctaacgcg ataattgctt ctgcaaattt ttcttttgaa cagtcacatt
     2821 tgaattgaac aggcattttt tccaaaatgt tcaattcttc tgtaccaagc aatcctttca
     2881 atatttcttc tggtgtctgt ccttcatcta agagggtaga gattcttggt gtcgttttta
     2941 attgttcttc gatcttgctg attgtttctt catcggcacc tggcatgatt tggatcatga
     3001 atcctcccgc cgtcttgatg ctgtcgtcag tattgaccaa tacactcagt ccaacagctg
     3061 aagggatttg ttctgagata gcaagatagt aagtaaaatc ttcagcgatt tctccagaaa
     3121 caatcggcgt ttgcccagaa aaaggttctt ttaatcctaa gtcttttgtg acagtaaaca
     3181 ttccttgtgt tccaactgct ccccgcacat cgattttacc ttcactattt agaggaagac
     3241 tgagatgcgg atttttgatg taacctttca catctccctt tccatttgca tctactacaa
     3301 ttcctgttgc tggaccatcg ccttggattc gaacagttag tttgtcttct cctttgagcg
     3361 tcgcaccaag tagcagacta ccgaccaatg tccgtcccaa agcagctgag gaggtgtgcc
     3421 aagtatcatg acgtctttgt gcctccgcta cggtatttgt tgcttgaacg gcgtatgctc
     3481 ggacgaatcc gtcgtgagca agtgccttaa ccaaataatc tttcatttgt tatgtactcc
     3541 tttttccgtt tttaaactca tagtgaatca tactagcaac tactgctttt ttcaactttg
     3601 gaatgcttct tttaaaaata attcagaatc atctagaaaa caggacatca ccctatttac
     3661 aacttaaata aagaaatctc ccgaaaaccg gtttttgttc cggttttcgg gagtcatatc
     3721 agatcaattg acctatattt ttttatttgt attgatcgtc tgaatgatta tcttctgatt
     3781 gttgagaatc tgaatcatgt tctgctttat tttcctcatt cagttcatgt tttgcttctt
     3841 caaaatcacg tttttcttcc gcttgttttt cagcgtcttt ttcttccaaa gcacgttttg
     3901 cttcttcaaa agttttcgct tctttttcgc ttggataatc atttgactca gtaccttcag
     3961 gcatcacacc gtgttcaaac aatgacttga ttgctttggc atccaatgtt tcgaattcca
     4021 aaagtttttc agcaatcagt ttatgctgtg cacgatgagc ttcgatgatt tctcgagctt
     4081 tatcatgagc ttccatcaag atttttcgta cttcttgatc aatctcgaaa gcgacttgtt
     4141 ccgagtaagc ttttgtttga ccatagtcgc ggccaacaaa cacttgatgg tttccttcat
     4201 attgaacagg acctaaacga tcactcattc catattctgt taccatgctt cgtgctagag
     4261 ctgtcgcttg ctcaaagtca ttggaagcac cagttgattg gacattgaag atgatttctt
     4321 cagctgtacg tccaccaagt aagcctacga tttgttcaaa catatcttct ttcgtcatca
     4381 agaactgatc ttcttttggt aaagcgatca tatatccgcc ggcgcgtccg cgagggatga
     4441 tcgttacttt gtggacgacc cgagcgcgac tcaatactaa tccgacaatc gtatgaccag
     4501 cttcgtgata agcaaccatt tcgcgttctt ttttgctgat tacgcgatct tttttagctg
     4561 gacctgcaat cacgcgatct tccgcttcat cgatatcaga agcatcgatt ttctttttat
     4621 ttcttctagc agctactaac gctgcttcat tcaagacatt ttctaaatct gctccggcaa
     4681 aacctggtgt ctgttgagcc acaactttca agtcaacgtc atctgccatc ggtttattcc
     4741 gtgcatggac tcgcaagatt gcttcacgac cttttacatc tggacgtcca actaaaatct
     4801 ggcggtcaaa acggcctgga cgtagtaacg ctgggtctag tacatcagaa cggttggttg
     4861 cagcaatgac gattactcct tcatttccgt cgaagccatc catttctaca agcaattggt
     4921 tcaatgtttg ttcgcgttca tcatgtccgc cgcccatacc ggcaccacgt tgacgaccta
     4981 ccgcatcaat ttcatcaatg aaaatgatag ctggtgcgtt tttcttcgct gtttcaaaca
     5041 aatcacgaac acgacttgct ccaacaccga caaacatttc tacgaaatca gaacccgaga
     5101 tcgagtaaaa cggtactcca gcttctccgg caacagcttt tgctaataag gttttacctg
     5161 ttcctggagg tccttctaaa agtacacctg ccgggatacg ggcacctaat tcaacaaatc
     5221 ggcgaggatc tttcagaaat tcaacaactt caactagttc ttgtttttct tcttccgcac
     5281 ccgctacatc agaaaaacgt acgcgattag cttttttgtc tgcttctttg gcttttgatt
     5341 taccaaagtt catgacacgg ccgccaccgc caccgccgcc gccttgttgt cccatcatca
     5401 tgtaaaagaa aaagatgatg attacgattg gcaagaagct aagcaatagg gaaacccata
     5461 taccgctgct tgattcttct tttactgttg tagcaacttt gttttctttt gccagttctg
     5521 ttacttggct caatgttgta tcatttggca aaatgattgt tgtgaaatgg gtagtagtcg
     5581 tatctgttga acctaagata gctaacccac cgctgttagc gacggtctgc tgttctttgt
     5641 attcaccagt gatcttatat acaccatttg caggctgcac ttcaaattct ttgatcttgc
     5701 ctgcttgtag ttgttctgtg aattttgagt actcgatatc tgacgatcgc tggccgttat
     5761 taccaaaaat gaaataaacg accattacca tcgctaagat tacgaggaca taatacaagg
     5821 catttttcat catgccgttg ttctttttgt tcatagttgc cctccctaag cgtcaattta
     5881 atttaacagt tttttatcaa tcctgaccat tctattgtac cataatttaa ttgagataca
     5941 gcattaattt gattgataaa cactaggttt caatacaccg atgtacggaa ggttacgata
     6001 tgcttctgca taatccaagc cataaccgac cacaaattca tttggtacgt tgaagccaac
     6061 ataatctgct tcgatattta ctactcttcc ttcaggtttg tcaagtagtg taacaatttt
     6121 gactgatttt gctttgcggt atttgaaaag atccactaaa taagcaagtg ttcttccgct
     6181 gtcaatgata tcttcaacga tcaacagatc gcgaccttct acattcgtat ctaagtcttt
     6241 gacgattttt acttcccctg acgagactgt tgcattcccg tagcttgaaa catccatgaa
     6301 atccaattcc aaatacgtat cgatagaacg aacgatatct gccatgaatg gtaccgctcc
     6361 ttttaagaca cctactacta ggggattggt gttttggtaa atttctgtta actctttgcc
     6421 tagttctttg caacgaactt gtatctcttc ttgtgagatc aaaattctct caatatcctt
     6481 ttccaacatc aggttctcct tccaattgct tctttttgat atttgtaaag aagtatgtag
     6541 tgtattttat cagtttcttc acgaatactc aaatatgaaa aggcaaaagg tatcaagcta
     6601 tatatatttc ttttggcatc tgtaatgatc caagcatgct gcctttgtga attaggtact
     6661 ttctgatcga taaaatatct agatactttt tttgtgagat tctctgttaa tttaatgcgg
     6721 tctcctgctt ttcttttttc gacatacagt tgcacatcag caggaatcca aatgtcatga
     6781 gaaaatagag accatgaatc tgttgctttg atgtcccctg cattttcagg tttgaccaga
     6841 ccaatccatt ctgtttcatt caaatatatt ccttgttctg gaatcagcaa caagcgctgg
     6901 tcttctgtct ggctagttgc ttgtttttct tttttagaga gtacaacaaa atgatactct
     6961 cttttcagta tccaattatt gccaatactg agttgccatt ggcttttttt ctgttgccac
     7021 tggtctaaaa tcgactccat ttgttgttct ttcaaaataa ttcctgtttt tgagaatgct
     7081 ttgtcgaaaa aggagtaaaa aaaatagtat cgttcagcat ctgtcatttc ttcaatcatt
     7141 tctgcagaaa atcgaaattg ttcctcccac tgttcgactt ccttttcgat caactgtccc
     7201 atatattttt gaatgacttg gtctgcccat tggatctgtt gcgaaaattg ctggaaatgt
     7261 ctcaacgcct gtgtattttc ttgtttcaat tgaggaacta ccaaatgacg aagccgattt
     7321 ctctggatat ctaacaattg gtttgtctga tcctcaaagt aaacaagctg cgattccgct
     7381 gcataagtat ataggtcttc tttgctaaaa ctcagcaacg gacgaatcag tctgcccgta
     7441 gcaaatggtt gtacttcttt gattccagaa aaagtattta actgtccccc acgaacgatt
     7501 ttcattaaca ccgtctcgat ttgatcatct ccgtgatgag cagtcatcaa cgtgtcatat
     7561 tgtccttctt ccatcacgcg agtgaattct tgataacgaa agttacgagc ttctgtttct
     7621 atggcggatt tggctggatc ttcccaaata cttacatata aagggagatt cttctcttca
     7681 caatatgagc gaagataggc agcttcttct gctgattctt ctcttaattg gtgattgatg
     7741 tggacgatac ctaaagaaaa accgatttgg cgttgcactt gtaaaagtaa atggagcaaa
     7801 accatcgaat caacaccacc tgataccgct gctaaaattc tcgatccttg ttgccagaat
     7861 ccttgttcat tcccgtgccg aataaatgac tgctgtaata gcggtgcttt tttcccgcct
     7921 ttttcaacgt tcatcctttc cacacccttt cttcctaaaa aaaagagagc gggaaaacgt
     7981 ctaaaacgac aattaacctg ccctctgttg atactatgac ccaaatagtc gcactatcat
     8041 tatttgcggc tttttagctg cgacgtccgc cacggccacc gcgctttcct tctgtgtttc
     8101 gcttcaatga agataagcgg tcatcgctat ctttcaaaaa tgaactcatc aatgaatcga
     8161 agtcttcttt ttgagctgaa ggttgactgc gagaaaaaga ttttttctgt gctggacgat
     8221 ttcggttgtc acggggatct ttttgttgat attttttagg acggctttct tctccagatt
     8281 cagcaggttg ttcctgcgct ttccggatag atagtccgat ttttccatca tcatttactg
     8341 aaataacttt aactgttact tcatctccta cacttaaaac atcatggatg tcttttacat
     8401 agccatttga cacttcgcta atatgaacta gacccgtttt tccagcacct agatcaataa
     8461 acgcaccaaa atttgtgatt cctgatactt ttccttgcag ttttgctcct acctcgattg
     8521 acataaaaaa aatgttcctc ctaattattt ccctttttta tattcctgct tattttgcag
     8581 ttgtagaact agttgattga tctgtttcat ttgtcgagct gtctgtattt gattctaata
     8641 taggataaac tttttcaccg tcttttgagt aaaagaattt gcttctggca agtttagcta
     8701 catactcatc atctttcagc aatgaaacat cttggtgcag ctgatcaacg tctgcgttga
     8761 cttctttcat ttcagtattt gcttcgactc tcaattcgtt caattgatgc atcctttgca
     8821 tgtcatggaa aatctgcaca cctattatcg cgaaaatgac caaagcacca acaaaaattg
     8881 cagccagtct gcgtcttcga aaaatcagtt gacgttgttg ttgctgaaat tcagcatact
     8941 ttttctttgc atattccgta tctagcgcag cgattttatt gctttttttc gtcacttgga
     9001 ttcgctccaa tctttttgat tgtctttttc attataccaa tatcgtgaaa gcttgtctaa
     9061 tctatttctc tagtgtttct gtgcgatttt cagaaataat ttcgtacatt ttttgtgcat
     9121 cttctttttt ggttgattca tgtaattccg taattttcac ttccaacgtt ttgttgccaa
     9181 actggacttt caaaatatcg cctactttga catcactgga agatttcgcc aatttaccgt
     9241 tgatttgaat tcttccttta tcagctactt cttttgctac tgatcgtctt ttgatgattc
     9301 gggaaatttt taaaaattta tctaatcgca tatcttattc ctcacttttt aattttttta
     9361 tttaatcgca ggattttctt accaaaaggc aacattagcc attctcgtac tgtaaacaga
     9421 cgaagacgaa tcactgcata aatgaacaca gaagccccga tcccaactcc tatcacgctg
     9481 acaaaaaaag cagtggaacg atgagttaca ggaccaaata ctatattcaa tacaccataa
     9541 tacagcagca gtactactgt catacaaaga aggctgaaca tcaacttccg tccaaaatgc
     9601 cgttctttcc aaaaagcatt tagctctttt gtttcaattc gaacaaaata ccaaagcgtc
     9661 acacctaatc ctaaaagggt agacaggctt gcacctgctg ttcctaataa accggtcaga
     9721 aaagaagtag tcaatccttt taccaatagt ccccatcctg cgccttttaa agaagggcga
     9781 aacgagttct tgctttgagc aatactttga taagcttgga tgactgcagt gaaagcaatg
     9841 gaaaaaacaa ataatacaag cgctgcattt cccgcataat ctttaaacaa cgcataattg
     9901 atataaggga gcagcaaggc taatcccaaa gacgcagcta atgctaaagc ggtcgtcaat
     9961 ctaagataga ttttggctgt ctgtaaaaac tgacgataga tccggttggt caaatgacga
    10021 gtcaacgcag gcaggaatgt cgcacttaat gcagtggcaa tcactaaacc taattgtact
    10081 aaaggctgac ctcgatcata gacccctttt gctatcttcg caccgtattc tgacagtccg
    10141 taaacttcca aagcattttt tacaaagaaa gagtcgatca gctggaaaaa gataagcaat
    10201 ccactataaa tcgaaaccag tccgccttct accagaaaac gccggatcaa gggctttgac
    10261 ggctgtttga acaatggaaa ccgtcggaag cttaacgctc ctccatgaat cttttgttca
    10321 tagtagtgaa ggatcccata tgcgcataaa ccgccaaaaa cagctccact cattgctgcc
    10381 gtccctgttt ggtacaccgt ccatccaagc tttctaaaag caaacgcact acagacaatc
    10441 acaaaaacac gaacgaactg ctcaactact tgagaaacag cagttggttc catcaagaat
    10501 cttccttgga aattccctcg ataaaaagat agaccaggca tcagcaaaaa ggtaaaggaa
    10561 actacttgga tcagcggttt caattgtatg tctcccatca tccaagcaat ccagctgcta
    10621 aatgcaaaga caaacaacca caaaaagaca cctgtccaaa atactaaggg ataaagattt
    10681 tgcaaagctt gctttcgctc gaaaggattc tttctttctg caacgtactt tgatatgaac
    10741 tgcggaagac cggataaagc taaagtcatt gctatcccat aaattggata aacttgctga
    10801 taaacataaa aaccttcgtc gccgactaag ttttggaggg gaattcggta aagggcactt
    10861 aatacttttg ctatgaaaga agcaatcgtc aatacaaatg ctccttgcat gacgcgccgc
    10921 atttctttat gatccaaatc attgctcctt cctacgctga cagatatttt tgctcacgca
    10981 acgctttgac aaacttttgg atttcctgaa gccatactgc ttcttccatt tggttgggga
    11041 tcgtcaagcg tatcaccatc tgttcttttt caacgcctag actggctttt agttttgtcg
    11101 ctgtcagtgc ttcgaataac tgttccacac tatagcgttt tgttccaact ttacttagag
    11161 taaagactat atgcgcctcc tgtttcctta tcgtttctag gagcgctcga tcgccatcca
    11221 ttttgatctg cccaattgtc aagagatgtg ctacttcttc tggatattct ccaaaacggt
    11281 cgagcagatc atcttctagt tcatctagca tttcttgcga atcaagttca cgaattcgtt
    11341 tatagatctc gattttctgc cgttgatctg ccacgtatgt ttcaggtaga tacgcatcga
    11401 caccgaggtc gatctcaaca gtggtcttct ccacttgact attctttcct tgtttacgag
    11461 aaacagcttc gcttagcatt tgagaataca tatcgaaacc gactgcatca ataaatccat
    11521 gctgctgagc acctaagaga ttacctgcac cgcgaatgga aagatcccgc atcgcaatct
    11581 tgaatccaga tcccagttct gtaaaatctt tgattgcctg aagacgtttt tcactgactt
    11641 cgttaaggat cttctgctgc tcatacataa agtaagcata tgcgacacgg ctgcttcttc
    11701 ctacccgccc tcgcaattgg tataacgtgg ataatcccat ataatcagcg ttctcaacga
    11761 acaacgtatt tgcgttcggg atatctactc ctgtttcaat gatggttgta gtgacaagaa
    11821 catcatattg accttcaata aattcaaaaa gcgtattttc taattgcgcc tctgtcattt
    11881 gcccatgagc ataaccgatc cgtgcttccg gaacgagttc ttggatttct tctacttttt
    11941 gttcgatcgt ttctacccga ttatataaat agaatacttg tccacctcgt cccatttctc
    12001 gatggattgc ttcgcgaata gccccaggat ttttttccat aacatacgtt tggatcggat
    12061 aacgattcgc aggcggtgtt tcgattactg aaagatcccg cacgcctaac atcgacatat
    12121 gcaaagttct cggaatcggt gttgcagtca gagtcaaaac atccacttgt gcacgtaact
    12181 gtttcaatcg ttccttatgt tttacaccaa aacgttgttc ttcgtcaatg atcagtagac
    12241 ccaaatcgct aaattcaata tcttttgaca aaattcggtg ggttcctaca acaatatcaa
    12301 cttgacctgt acgcagttgt tcgatggttt ctttttgttg ctttcttgtt ctgaaacgac
    12361 ttaatagccc gatatttacg gggaaacctt caaatctttc cagcatcgtt tcatagtgct
    12421 gctgtgccaa gatcgttgtt ggaactaaaa aggctacttg tttgctttcc tttatcgctt
    12481 taaaggccgc tcgaagcgct acttctgttt tcccataacc aacatcacct acgagtagtc
    12541 gatccattgg tttttctttt tccatatccc gtttgatctc cgctgcactt ctcaactggt
    12601 catcagtttc agagtagggg aaggcatttt cgaattcttt ttggtaggcg tcatcaggtc
    12661 caaaagcata tcctttttct gactctcttg cggcatataa tttgattaga tcgtcagcga
    12721 tatcctcgat ttttgaagag acttttcgct tggttttcgt ccattcactt ccgcctagct
    12781 tattgatgcg aggcgctttg gcttcagagg cgacatattt ttggatcaga ttcagttgag
    12841 taacaggaat aaacagtttg tcgtcgtttt gatacaaaat agtcatatag tcttggtgaa
    12901 cgccatctac ttctagcgtt tccatcccaa tgtatttccc gataccatga ttggcatgga
    12961 caacgtaatc tcctgctttt aactcattat agcttttcaa tcgctctgcg tttgttactg
    13021 tttgacgtct cgtttgtttt ttcgtcgttt tttggaaaat ttctttttct gtgatagcta
    13081 ctattttttc ttgaggaagt tcaaaaccag cctgcaaagc tccttcaact aattgtacct
    13141 gtcctctgat caatgcattt ttttctgttt ctactactaa tatgtcttca tctcgaagca
    13201 tttgttctgc tttgcgtatt ctgtcctttg tcggaataaa gatcacaaca gtctgttttt
    13261 gcttgcgcca acggtccatt tctgttttca gcaatggcat ttgtccgaag aactgttgca
    13321 tcgtccgata ttgaaaatta tggattgctt ggaaacgaag atttcccatc cctttttgga
    13381 agagtgagaa aaaggttgtg gtgaactttt ccttctgcac gattttttgt atatctgctg
    13441 aaaatgtctg ctcagaaaac acccgcaatt cgctgatttt ttgagtctgc cattctgccg
    13501 cttccctttc gatttcccga tttgtttcca tgattcgctg ataatcatca acgactagta
    13561 aactatttga agggaaataa tccaagatcg tcacagattc ttggtaaaga agatctgagt
    13621 agaattttgc ttcttctgtc gggacacctg cttgccagct tgaagtcagc tgaccgaagt
    13681 aatcttgcaa aaactcgcgg tctgcttctt ctgtggtcgc agcaagccgt ttttctagca
    13741 ttttttgcat ttgctctatt ccatgttcta gatcctctgg tccgtagact tgttcactcg
    13801 ttggggaaac ccagatttct tccgtttttt cgattgagcg ttgtgtttct gcttcaaaat
    13861 accgcataga atctatctct acatcaaata gttctacacg aacaggatag gttgtcgtta
    13921 acgggtaaat atcgataatg cttcctcgaa tactgaattc tcccggtttt gcgaccatct
    13981 cttctcgtac atagcccatc aaagtcaatt ggcgaggaag attttccacg tctatctcat
    14041 caccaatatg ccaattcaat tgcgcctgta gccaagtttt cttattcggc agtcgtttgt
    14101 gcaaagatgc gactggcaac aaatagatac ctgctttttt ttcttgaagt gcgttaagcg
    14161 ttgcaactct ctcgcctcgc gcttctggag aagaaaaggc catttcagca gaaagcactt
    14221 catccactgg aaataaatgg atctgatctt gcggaatcac atgttgcaga tcttctgcta
    14281 actgattcgc ataatacaaa tttggcatca gaataatcat gtttttattt gttttcttaa
    14341 acgctcgagc aaatagaagt gttttcgctg agcccgctaa tcctgtgatt agttgtctag
    14401 gcattttttc ttctaaattg ctgacccatt cttttacttg cggatctttt ccgactaatt
    14461 gaataatatc cattcctttt cctccttcct caattgaatc gattcatcgc atccacgaac
    14521 gaatgccctt ctatgagata ttcgactgct ttaacagatt gacacatgct ttcttctatc
    14581 aaaggctgat tttctttgct gaaaggacta agcacatgct ggactactgt ttttttccct
    14641 tctggcctgc cgattcccac cttgattcga tcaaagacat tcgtattcaa atgggaaata
    14701 atacttttga taccgttatg cccgccggca cttccctttt gacggagccg gatttttccc
    14761 actgccagat ccaaatcatc gtagattacg actaattcct ctggataaat cccaaaataa
    14821 gtcattagtg ggccgactgc acgaccagat tcattcatga atgtttgtgg tttgactaaa
    14881 aggatctttt ctccattatg aaaaaattcg gcaacttctg cttcgaacgg attttttttg
    14941 aaagtagctt gatgctcgcg tgcaatttta tccacgacca taaagccgat attgtgtttt
    15001 gtatattggt atttggtacc tgggtttcct aacccgacga tcattttcat ttttgttttc
    15061 cacctaattc taaaaagcag cacaaaaggc tggactgcta attagcggtc cagtccatcg
    15121 agcttttttc ttttttacac ttgtcaatgc atagtataac acaaaacaag gcgtttcggc
    15181 taaaagagaa tcgttaataa atgataaaga aattaaaaat ttcttcaaag tttaatgaaa
    15241 taattgatat ataaaaatag tgaaataacg cacatgtaag cttttacata taatacaacc
    15301 ttgttatctg ttatatttta tagccaaata gcgtgacatg gggcttgaga aatgttagca
    15361 taagcatggg aaaaaacaaa tcaatggaag gattgatact aaatgactgc agctgcagaa
    15421 aaaaaagatc atcaaaaagt tattcttgtt ggagacggcg ccgtaggttc tagctatgcc
    15481 tttgctctag ttactcaaaa tatcgctcaa gaagtaggta ttgtggatat caatactgct
    15541 aaaactgaag gagacgcaat tgacttgtct cacgctttgg catttacttc acctaaaaaa
    15601 atctattctg ctacttacgc agacgcacat gatgctgact tagttgttat tacagctggc
    15661 gcaccacaaa aaccaggtga aactcgttta gacttagtaa acaaaaacct aaaaatcaac
    15721 cgcgatgttg tcacacaaat cgttgaatca ggatttaacg gtatcttttt agttgccgct
    15781 aacccagtag atattttgac ttactcaact tggaaattct caggtttccc taaagaacgc
    15841 gtaatcggtt caggtacctc tcttgactca gctcgtttcc gtcaagcact tgcggaatta
    15901 gttgacgttg atgcacgtaa cgtccatgct tacatcttag gtgaacacgg agattcagaa
    15961 ttcccagttt ggtcacatgc aaatgttgcc ggcttgcaaa tctatgaatg ggtaaaaaac
    16021 aacccagaaa tcgatgaaga agctatggtt aacctattct ttggcgtacg tgacgctgct
    16081 tacacaatta tcgagaaaaa aggcgctact ttctatggta tcgcagtagc attagcacgt
    16141 atcactcgtg ccatcttaga tgatgaaaat gctgttcttc ctttatcagt attcatgaat
    16201 ggcgaatatg gattgaacga catctacatt ggtgcacctg ctgttatcaa ccgtcaaggt
    16261 atccaaaaag taatcgaaat tcctttaagt gacagcgagc aagaccgtat ggctgcttct
    16321 gctaagcaat taaaagaaat tctagatgaa gcttttgcta aactagacgc tgaataatct
    16381 ttgaacatga cggaaaacat ctattcggtg ttttccgttt ttttatttta tcacccttat
    16441 ggtttctaaa ttttttcata aagtagagat aaccttcgtc ttttcctcta aattatgcta
    16501 tcatgagacc gttccaccct aaacttttac ttaaggagtt gtcgatatga caagatcttc
    16561 gcatcgaaaa aaatcgaaac atgttgcttt gctttcagtt cttggtgttc tcttagtgct
    16621 gatcagcttt tatacctatc gcagtacata ctacacaaag cattttttgc cgaatacaga
    16681 aataaatgga ataaatgtca gcaatctaac agtcgaaaaa gcaaatgaaa aattaaaaga
    16741 agcttattct gataaaaaac tggctattaa agaagatgga aaagtctggc aggaagtacc
    16801 aaaatccgag ctcggctaca aagatgattt cacttcggag ctttctccga tcctaaatga
    16861 acaaaacgga tggacttggg gaatgactta tgtctcagcg gcagaaaaac aagaaataga
    16921 tcctgtcagt caaaaccacc aaaaactaga cactaccgtt cagacattga caactaagct
    16981 gactgatttg aacaaagacc ggacacctac tactgatgca acgatcgaaa aagcaggtga
    17041 ctctttcgtt atcaagcctg aagtcaatgg aaatacgatc gacgtcgatg ctgcggtcaa
    17101 acaattaaaa agtgcggtaa actctggtaa agatacaatt gaattgactg aattcaaaga
    17161 aaaaccaaaa gtaacatctg aagacagctc actgaaagaa caactcgcat ccatgaatgc
    17221 tatcgcaaat gtaaaagcta cttacagtat aaacggtgag actttccaga tcccatcaag
    17281 tgatattatg agttggctga cctacaatga tggaaaagtc gatttagata cagaacaagt
    17341 acgtcaatat gtaacagatt taggcacaaa gtataacaca agtacgaatg acacaaaatt
    17401 taaaagtaca aaaagaggag aagttacggt cccagttggc acttacagtt ggacgatcca
    17461 aacagacagt gagacagaag cattgaaaaa agcgattctg gcaggccaag attttactcg
    17521 ttcacccatt gtgcaaggtg gcacaaccgc tgatcatcca ttgatcgaag atacgtatat
    17581 cgaagttgat ctggagaacc agcatatgtg gtattacaaa gacggaaaag tggcccttga
    17641 aacagatatc gtttccggaa agccaactac acctacacct gctggagtct tctatgtttg
    17701 gaataaagaa gaagatgcaa ctttaaaagg aacaaatgac gatggaacac cttacgagag
    17761 tccggtaaac tactggatgc cgattgactg gacaggtgtt ggtatccacg attcagactg
    17821 gcaacctgaa tacggtggag acttatggaa aacccgcggt tcacacggct gcatcaacac
    17881 cccaccaagt gtaatgaagg aattattcgg gatggtcgaa aaaggaacgc ctgtattggt
    17941 cttctaacaa aaataatata taaaaagaaa gcacccgtac gattggtaca ggtgctttct
    18001 ttttattatc taacaatgtg ctacttacat ttcagcagca gtaaagactt ctgaaacatc
    18061 atcatcgtct tctagcttat ctactagacg ttccaattgc tctttttgtt cctcatttaa
    18121 atcaatcgtc gtttgtggaa tcatcgtcaa ttctgcttgc gccaaagtga actctttttc
    18181 caactcatct cgtacagcag caaaatcttc tggtgcagta taaatctcga atacttcagg
    18241 agaagtttgc agatcttctg cccccgcctc taatacatcc tcaaacatcg tctcttcatc
    18301 aacagtcaac ccatcgcgtt caatagcgat atatcctttg cggtcaaaca agtaactgac
    18361 tgaacccgtt tctcccagtg atccaccgtt tcgagtaaaa gctactcgga catttgtcgc
    18421 tgtccgatta cggttatctg tcaatgcatg gactaagatt cctactccac ccggaccata
    18481 tccttcatac gtgatttcat cgtaattcgt ttcatctacg gcactcgtag cctttttaat
    18541 cgcccgttcc acattgtcgt taggcatatt tgcagctttt gctttgtcca caacaagccg
    18601 caaagctgga ttcatagatg gatcaggacc gcctgcttta gctgccatat aaatttcacg
    18661 agaaagtttc tgaaagactt tccctcgttt tgcatcttgg gcattttttc ttccttggat
    18721 attatgccat ttactatgtc ctgacatgat ttttcctccc ttgttctttt gagaatacac
    18781 ttctattcta gtactatttc acaaaaaaac aaagccacag ccaatctata aacgcttctt
    18841 gaatgccgca aaaagcacac ataatatcac agcagtcaga gcaccgatcg aatccaacat
    18901 gacatcttgg aacataggtg ttcgtccacc ggtcatcatc tgatggaatt cgtccaaacc
    18961 tgcgtaccct gttgctgaaa gccaagcaag gatcgctgtc agccaccaaa tttttagctt
    19021 ggggaaaaca cctaaaaaca agctgcctcc caaaataaaa taggtaccga aatgtgcgcc
    19081 cttccttaaa aagaactcta aaaatttggc gtagcccaga tggttgatac tcaccatact
    19141 tccaccataa ttaaaacgta tacccgctaa tgtgtcttta aatggctgat taggcagcca
    19201 gctttctaat cgcgaaactt gtgattgctg tccgtaagtt tgagaagaac tgtaaaataa
    19261 gattataacg actatcagtg cgattactaa ataaatattt ccgtttttca tttgtttttt
    19321 tgaagaattc ataagtcacc tctgtatttt atcttagact ttttttgaag aaacaacaat
    19381 cattttcata gagacttctt ccataaaaaa gtgctatact taattttgta ttacaatatg
    19441 aagggagttt tttcatgagt tattcattaa attggaatct agattctatt ttttccggag
    19501 gcagtcattc tgatgctttg aaccaacgga tgaagcaatt ggaagaccaa atgaacgagt
    19561 attatcaccg cgtaacaaaa tggtcaccta gttctgacaa tgcagagcag ttaaacgcta
    19621 ttcttcaatt gcaagaaacg attacgaatg gttttaccca atgcagcagc tatattactg
    19681 cattgctttc tgccaatgtc aatgattcag atgcaaaggt cttatcaggc aagctttacg
    19741 caatgctgcc tcgtctgcaa tcagccgaaa ctgtattgtc aaagaaattt gcagaaatat
    19801 ctgacaatga ttggaatcag atgctttctc aatcttcgtt tgaaacaatt gcttttcgtt
    19861 taaacgagat tcgtcgtgat ggctcacaat tattatcaga agctgaagaa aacattataa
    19921 atacgctttc tttagatggt ctaaatgctt ggagcagtca ttatgatacg attgtagcca
    19981 gcatttcgat tcccttcgaa caagatggac aagtagtcga attatctgct ggacaagcct
    20041 tcaataagat gatgggcgat ccagatccaa aagtcagaga aacacttttc gcagcatggg
    20101 aagaagcctg gaaagaaaag gcacccctct tcacggatac tttgaatcat ttagatggtt
    20161 ttagactttc tgactatgaa cttcatggtg tcacagattt tctacaaaaa ccattagagt
    20221 acaatcggtt gaagaaagaa acattgtctg tcatgtggga tacaatccag aaaaacaaac
    20281 aaccccttgt taattacttg actagaaaag ctaatctttt cggtaaagaa aaaatggaat
    20341 ggcaagatca agatgcacct attattttag gcgatttgaa agaaaaaacc tttagttttg
    20401 acgaagcagc agcatttatt atcgaaaact ttaacaaatt cagtccaaaa atggctaaat
    20461 ttgcccaatc tgcttttgaa aagagctgga tcgaagcaga agatcgtcct gggaaacgtc
    20521 ctggtggtta ttgtactgag ttaccagaaa caaaagaatc aaggatcttt atgacctaca
    20581 gtaattctgt taatgaggtt gcgacacttg ctcatgaact aggacatgct ttccatagca
    20641 gcacgatgtg ggatttacct tctttaaatc gcgaatatgc catgaatgtc gcagaaacag
    20701 caagtacatt cgcagaactg atcgtagccg atgctacatt aaaagtcgca aaaacaaaag
    20761 aagaaaaaat caatttgcta gatacaaaac tgcaaaatgc tttagctatg ttcatgaata
    20821 tccattcccg attcattttt gaaaatcgat tctatgaagc acggcaagaa ggattagtct
    20881 cagaagataa gatcacagag atgatggttg aggcgcaaaa agaaggctat caaggagctt
    20941 tagctactta ccatccatat ttctgggctg caaaattgca tttctttatt gatgacgtac
    21001 cgttttataa cttcccatac acatttggct acctctttag tttgggcatc tatgcttacg
    21061 ccaaccaaaa gggagcaaat tttgaagaag aatatatcca tttactacgc gatactgcct
    21121 caatgacgac ggaagatctt gcgaagaaac atttgaatgt cgatcttacc caaccagatt
    21181 tttggcaagc aggtatcgac atggtgactg aagatatcca aacgttcatg gaattgacag
    21241 aagaatttat ctgatttcta ttttatcaca ataaaaaaag agttagtcca gaatgggcta
    21301 actctttttg attaatcatt cttacatgct gacagcaaag tcaggggcaa accattgaac
    21361 tgaaccaact tttacgcttt cgcctggttg aggagcatgg atatattgtc ctccgcctaa
    21421 agcaatcgct acgtggtaag ttccgccttg tgacccccag aataacaagt ctccagcttt
    21481 tgcttgagaa actgaaattt ttgttccagc tgattcttga ggaactgtcc aaccaccgat
    21541 gtcacgacca gttacttgca tgtaaacata gcgtgtgaac cctgagcagt caaagccact
    21601 tggatcttta ccgccccaaa catatggagt accaatatat ttgtaagctt ctgctacgat
    21661 tgctgcacca ttcacacttc cagaaggagc tggagcaggt gttacaggtt ttggttgttc
    21721 aggtgttggt gttggcgttg gagccggagt actacttcct gtgccgtttc ctgtatcaac
    21781 actttgatct gttgatggtg ttgtaggcgc aggtgttgtt gattcttctg ttgttgaaga
    21841 ttcaggcact gttgttgatt cttctgttgc tgaagattca ggcactgttg ttgattcttc
    21901 tgttgctgaa gattcaggca ctgttgttga ttcttctgtt gctgaagatt caggcgctgt
    21961 tgttgattct tctgttgctg aagattcagg cgctgttgat tcttctgttg aagattcagg
    22021 tgttgttgat tcttctgttg ctgaagattg tgtagctgat gatgattctt cagtcattga
    22081 agattgtgta gctgatgatt cttctgttgc tgagctttgt gcagtagatg aagcttgagt
    22141 agcttgtgct tcagcctctg cttgttcgcg tgcttctttt tcagcttttt cttgtgcagc
    22201 ttgttgacga gcttgttctg ctagacgttg ttgttcacga atacgagctt gctctgcttc
    22261 agcttctgct ttttgacggt tcaagtcagc tttcttgtct tcagcagttg cttgttcagc
    22321 agctaatgaa gttttcagta cgttcaaatc agcttgttta gataaaagat cgcctttttg
    22381 agattccaaa gcagcttggt tttcagctaa ttcttttagt ttagcatcgt tttcagcttt
    22441 tttgtcttct acagcttttt tatcttgttt ttgttgttcc atcaagtcgt tgtttgcttt
    22501 taccatcgtt gtcattgctt gaacgcgtcc aatagcatct gctaatgaat cagcattcaa
    22561 tacagcatcg atgtagtttg agcttgtgtt gcttacttgt gcttcgcgtg cttgtttttg
    22621 gattgtatct tcacgttttt caatacgttc ttgtaaatct gcaatgtctt ttactaattg
    22681 tgcagattct tgacgcaatg tatcttgttt tgctaatagg tcttgtgctt gtgtgttgat
    22741 ttcagaaact tggctttcta aggcatcgat ttgtgattgt gcatctgctt gttgattttt
    22801 caagtctgca atcttttgat cttgctgttg tatctgagaa tcaaaatcgt ccgccgcggc
    22861 agcgatcggt gatgctacgg cagtcaaggt cattgaacat accattactg ctgatattaa
    22921 actctttttc actcttcatt cctccgactg gcttaattta ataaatatct aaatatattt
    22981 aagtctttct taacgatata aaaattgtac catagcagtg tgtcaacgat ataatagtta
    23041 tgttacaaaa atgtttcaaa acaactttta aaaatgacaa aactgttcgt ttcagaaaat
    23101 gatcatgaaa aagccgcgtt aagtctagca tttcttaaga taacaacgat tctttttcgc
    23161 tttcgaccta aaaataaaaa aagaaattat tcatcactga ataatttctt aaagggaaaa
    23221 atgaataata caaatataat catgttcaac agcagtgtag gtcctaaaaa ccttgtaata
    23281 aaatacgtgt tatttactac tgctaattta aaaatcaact ggaccaccat cgtaaacaat
    23341 tcataacccg tgacaaagat gatcatactg aaaaattcag taaagatgtt gacatggata
    23401 acgtctttca ttacatacat caaccataca attaaaggga gagctactgc atagataccg
    23461 ataacgccaa tatagtaagc gtcatagata gccccgagaa caatcgtggt aatcagtaaa
    23521 taacgttttt caaacgccat actgcaacat aataatgcca atatcagaaa gtgggcattt
    23581 gacatatagg tgcctttcga ccactcccct agcattcttg ttaaatgacc atctatcaac
    23641 atcaaaaaga acaaaacgat tggcagatag tacttcattg tttctttctt caacatggac
    23701 taatcctccg ctagccgttg gacaatcgtc acaactgaca cgtcatacat ttctgcataa
    23761 ggtttcacat aaacttcccg atccagccca taactatctg gtttcgtttt aataaccgta
    23821 ccgatcggca agttagctgg agaattccct ccaagaccgg atgtctggac aacatcccct
    23881 tctttgatat ccgtatcacc agttaattgg gtcaccacta aggcatggag cttttcatca
    23941 tagtttttaa gcaaaccaaa cgcttcgcca ttagccgaag atacccgtac tggaaaatga
    24001 ttggagcttt cattagagga tgacagtaat tcgattttag acgaagccgt attgacctcg
    24061 atcactcggc caatcaatcc tttttgcgac atgactgcca tatttgcttc gataccgtct
    24121 ttagaaccct tgtctacgat cagcatgtcc tgccaactgt caggcgaacg agtaatgaca
    24181 tttgccgtta ctttttcgta actagtcagc gtctgattca actcaagttc ttttttcaac
    24241 gcttcgattt ctctctcgta attcttgttt tgctgtgaaa cgtcatcata gctatcgatt
    24301 ttttctttta gccgctcatt ttcggcataa gttgaaaaaa gattatggac agaatctact
    24361 ccatttcgta cccaccgtac tggggcagag attgttttat caaccattgc aacactgtca
    24421 ttaacgatgg attggaagaa attgggcttt ccttcattcg ctcgctgcgc agcggtcaca
    24481 cttagtatcg tcaccacgat gataacaata accaaggtaa taataatatt tttattagga
    24541 ttgaacttct tcacaaagac acctcgaatt aattagactc ttgtgttcaa ttttatcact
    24601 aaatgccgtg aaacaaaagg taagttgctc ctcttaagct tttttttagc aaataataga
    24661 ttctgtcatt tttagcctga aagacaaatt tttttatttg tttatggatc aatctttgct
    24721 ttgaataact gcaatcatac catctgaaaa agaaaattct gcggtatctg aaagaaattc
    24781 gttacttgca taagatgtcg gatattctac ttctttattt tccaatacat acttgctgcc
    24841 ttttaatgta agattcgaga cgggagtcaa gcagcaataa gctaaatact tcatatctgg
    24901 tatctgtctt actatatgct ctccaggcaa ataataagac aaataatttt gacaatctct
    24961 gataataagc tgatgggcaa agggtttgaa gcgaggttcc atacctaacc agagattggc
    25021 taaaagatga tccaatcttc cgcccgtagc tccaatcaaa gtgacttccg cttgcgggta
    25081 acgttcaaat gtttttaaga tacctaactg tgtatctgta tcgtcttttt ctgcagggga
    25141 acgggtatac tctttggctt ttgcaaatac ttccttctgc tcttcgttcg acaatgaatc
    25201 aaaatcaccc actgccagat ctactgggta gcctgcttga agcaggtaca gcgcaccacg
    25261 gtctatcccg acataggcat cgtatttgga cagcagagac tgcggccagt tttgcggatt
    25321 acctccagca gctaataaaa ttttcattta gtctaatgcc tcttttaatc gttcgatttg
    25381 tccgactgga ttttcggctc catagatata tgatcctgca acgaagacat ccgcccctgc
    25441 atctttacag atttttgctg tttctggaac gattccgcca tctacttcga ttgcataagt
    25501 ccaattgttc tctctacgta gatcagcgag ttccgtaatt ttttctactg tttcttcaat
    25561 aaagctttgt ccgccgaacc caggattgac agtcatgact agtacttgat cagccaaagg
    25621 caaaacatgt ttgatcatgg agactggtgt tcctggattg ataactactc cagctttaac
    25681 tcctaagctt tttgtcattt gaagtgcccg atgaatatga ggagttgctt cgacgtggac
    25741 agtaatgata tctgctccag cttttgcaaa tgctggaatg tagttttctg gatcaacgat
    25801 catcagatgg acgtctaacg gtaatttagt aacaggacgg attgcctgaa caatatttgg
    25861 ccctaatgtg atatttggga caaatcggcc atccattaca tctacgtgga tgtaatctgc
    25921 gcctcctttt tccactaact caatgtctct ttgtaaattg gcaaaatctg cactcaaaat
    25981 ggatggtgct atcttcattc ttgtttcctc ctattttcgt ttaccttctt tttttgcata
    26041 cattggtttt cttttttcga tttcttgtaa gaattgcaaa taattgtcgt aacgtgtctg
    26101 tgcgatacca cctgtttcta ctctatgttt tacttcgcag ccaggttctt tagcatgcat
    26161 gcactctcta aatttgcaat ggacagaagc ttctacaaat tcaggaaatt gtctcggcag
    26221 ttctcctgct tcaattgtca aaaagtcaat cgagctaaat cctggtgtat ctgctactaa
    26281 cccgccatag ataggaatca gttccacatg acgtgttgta tgccgtcctc ttccaagtgc
    26341 atcagaaatc tctcctgttg ctaaattcag ttccggtgat atttgattca gtagcgtcga
    26401 ttttcctgct ccagactgac ccataaagac cgatagccgt tctgggaagt aacggatcag
    26461 ttctgtcgta tcacccgtat gattgggtac aatcaccgga tagcctattt tagtataggt
    26521 ttgcttgatc tcttcgattt tttctgggtc gtctgacaag tcggtctttg tcaaaaaaat
    26581 aatcggttcg atcgactcgt attccaaggt aactagaaag cggtcaagta gattataaga
    26641 aaatgcaggc tctacgatac ttgtgacaat gattccaaga tcaacatttg tgactggtgg
    26701 gcgaactaat tgattttttc tcggcaagat ttccagaaga tagccgtctg tttgattttc
    26761 actctcaaag atcacctgat ctccgacaag cggcgtgatt ttccgattcc ggaaatttcc
    26821 tcttcctctt gtttgatagg tctctccgtt tgcgtataca tagtaaaaac cgctgattgc
    26881 ttttctgatt tgtcctttga taagtgccac ctccgttttt gtttatttta ccatacgaag
    26941 aggaaagtag gtgttattcc atgcaaactt ctcaaagtat atggcttgaa aattgatcaa
    27001 aagagataga aacacaaaaa agagaatgca acaaatcaat gtcgcattcc cttctgatat
    27061 attttattca gcacttattt tgaactttct gaggtgctag ctgatgaact tgtggagctg
    27121 gaagattctt cttttgaaga gttgcttgtg ctactggagc tacttgagct gctagaactg
    27181 tctgaagagt ctttttcaga actagaagac gctggatctg gtcctttaga gtaaattacg
    27241 ttcacaacca ttcctttggt aattgtcgtt cctgcccctg gtactgtacg aatcacttta
    27301 tctttatcca ccgtgtttga atattcggaa gtctcatgcc cgatatattc tgcaccgaca
    27361 ctagctaaat aactttgtgc ttcgcttttt gtatagccgg agatatcatt caatttaggc
    27421 tctgttcctt ggcttacgac aaaattgatg taagtttctt ctgctacaac ttcacccgag
    27481 gctggatcct gactgatgat cgaacctgat ggtacagtgt cgctatagtc ataagtagca
    27541 ctaatattat tgatattgaa tccttgtgta acaagccaat tacgaacagt ttcgtagttt
    27601 tctcctacat gactactcaa agtcactgtt tctggtcctt tgctgactgt gaaagtaatc
    27661 gtgtctgttt taggatcgac ttctgtatct tctgatggag attgcgaaat gatcattccg
    27721 ctttctacct ctgaactgaa ttcctcttct ttttgaatca agtcagcaga aaaccctaat
    27781 tctttcaaac ttgcttcggc atcttcataa cttttaccac tgtaatcatc taatttgatt
    27841 tttttcgtgc cgctactaat atacagagtg acttcgcgtt tttgcttgac tgtcgttccc
    27901 gctgccgggt ctgtcttcac tacattacct tcttcgattt tgtcatctgc aatttcttct
    27961 gtttttgttg ctacttctaa tttcgctttt gcgagtgttt ctctagcaga agcttcagaa
    28021 agatcagaaa catcaggaac aacaacttct cctcgcccgc cagaagcaaa gaatacagct
    28081 gttccgattc ctaaaacagc aagaatagct aataggatca gccaccattt tttctgtcct
    28141 ttctttttag gatcaggcag aacttcttcc tcctctggta aggtttcgtt ttctggcttg
    28201 tcttttggca gaggcataga tttgaatgaa tcaggcattg gtgcatcttc cgtaaggggt
    28261 gtgataactt ttgtttcatt atccatcaca tgaggctgcc atttttcttc gtttgcacga
    28321 gctggtgata atactgtaga aagatcatca gacatttcct cggctgactt ataacggtct
    28381 gcaggttctt tagccgttgc ccgtaaaatc acgttttcca gtgcttgtgg cacatttgga
    28441 tcaagtgctt ttatagatgg aagatcatct tgaaaatgtt ttaaagcaat tgttacagca
    28501 gattcaccat caaacggtac gctacccgtc aacatctcat aaaggatgat ccctaaagca
    28561 taaatatctg actgcttcgt tgccatactt cctctggcct gctcagggga cagataatga
    28621 acagatccta gcatcgtatt cgtctgcgtg atcgatgttt cagataaagc gatagcaatc
    28681 ccgaaatccg tgatttttac aacaccttca ttatcgatca gtacgttttg gggtttcaaa
    28741 tctcggtgga tgatttgatg gttatgagct aaagaaatag cagaaaggat ctgctgcata
    28801 atatttactg ctgtttcata aggaacagga taatgtgttt ggatatatcg tttcaagtcc
    28861 attcctttga cgtattccat caccagatac tgcatgttgt cttcttcacc aacatcgtaa
    28921 acactaacaa tgtttggatg aacgagttct gttgctgcta aagcttctct ctgaaatcgt
    28981 cgaatcgcag tctggtcatt ttgaaagtca aatcgtaaga ctttaactgc tacatcacga
    29041 tccaagatta aatcgtgcgc caaaaataca tttgccatac caccgctacc gatatttcca
    29101 gtgatttgat aacggccatt taattttttg cccaactcga tcatacactg tcctccttat
    29161 attcgataag aagaacggtg atattatccg ctccgcctgc ttcattggca cgatcaatca
    29221 gctcagttac tttatgagac aatgggcctt cttgattgat gatcgttcct atttcttctt
    29281 cagacagcat gttcgtcaag ccatctgaac ataacagcag tcgatctttt agttgccaaa
    29341 gatgagtaga aacatctact tcgactgttc caggcatgcc gacagaacgt gttaaaatat
    29401 ttttccttgg atggttcact gccatttctt cgctgatttc tcctgatttg actagttcat
    29461 tgactaaaga atgatcctcc gtcaattgca tgattttatc ttcacgaatc aaataagctc
    29521 tgctatcccc aacattggca atcgtgaacc agtcatctga cagagcggcc gctacgattg
    29581 ttgttcccat accgttatat tccggctgtt cttgtccacg ctgataaatc agcatatttt
    29641 cttcttgaat cgattgaatg aaccattggg cgattttttc atcgtcaaca gcttcttgtt
    29701 tttcccaagc ttcgcctaga ttcgttaccg ccatctgact ggcaatgtct ccggcacgat
    29761 gaccacccat cccgtctgct aatacagcaa gcttgagacc tgaacggctg gtaaatacac
    29821 tggcatagtc ttgatttgtg ttacgtcgtc ttcctacatc tgattgatat tcaatctgca
    29881 ttttttcacc tcattacttt ttgcgcaaac aacaaatgaa aaatccatct gtgtaaaact
    29941 gatgcggata caaagtcaac attttctctt cgattgatga ttgtagcata ggattggtca
    30001 aaacatcaat cctctcaaaa tcagggtgtc tttccaagaa agcagaaaca acgtcttggt
    30061 tttcttcttt taagatcgta caagtgctat aagtcagaat accggaagac tttaaagttg
    30121 gtgcgcagct ttctaaaatt tccaattgga tttttggtaa attcgctaat tcatccggct
    30181 gttttttata acgaatatct ggttttcgcc gaagcagccc aagacctgaa caaggcgcgt
    30241 ctactaaaat ccgatcaaac tgctctgctt cgaactgttt actgacttct ctagcatcca
    30301 tcttttgagc gtagacagca gaagagacac ctagacgtgc tgcattatct tcaatgagtt
    30361 tgactttgtg ttcgtgtaca tctaaagcga ccacttctcc accgcatgac ggatctaaaa
    30421 aagaagcaat atgcgtcgtc ttacctccgg gtgctgcaca ggcatctaag acatgatgtt
    30481 caggctcgat ttgcatagac ggcgctacaa gcatcgaact ttcatcttgg atcgtcatga
    30541 cgccatcgtg gaacaatgag ctagaagcta aatgcccttt tttcgctact ataccgtatg
    30601 gactgacttg gcttttttca gctgtgatct cttcttcttg caaaacagtg atggcctgat
    30661 ctctggaaag tcggcgtgta tctactcggg cactagcatg gctaggctga tatagcgata
    30721 aaccgagctt ttcagtttct tcgtatccga tttgatccac cagtcgtttc gtcatccata
    30781 gaggcaggct gattttgaca gaaagtcttt cgataggatc agcaatgcct tgcagatctg
    30841 gtgctccttg acgctgataa ttcctcaaga caccatttac aaatttccct gtcccaggat
    30901 ttccttttac ttttgcgatt tcgaccgcct cgtttaaaat agcatgtgca gggactttat
    30961 ctaaaaattc taattggtat acagaaagat aaagaagcat cttgacccag tcatccactt
    31021 tttttgcttt agcgatcaat ggtgcaacgt aaaattccaa tagtcgctga tggctaatcg
    31081 taccatagat caattctgta aataaaccca catctttttg atttagctcg ctttgtttga
    31141 tcatctcatt caacaaaaga ttcgagtagg cgccaccctt gttcactcgc tctaatgtca
    31201 gtaatgccat atatcgtact gattttttca tttttttagg gatttttttc attatttcac
    31261 ctgctgacca atctgaactt gctgaccgct tccgttaagg aaatcatgta cggcctgttt
    31321 tcctttacca gctggctgta attcattgat ggctaagacg gtctgtttac cgcaagcaat
    31381 ccatagattt tttttgtctt tccggatgat cgtaccaggt gctttgtctg tagtttctgc
    31441 caatacttca accgataata atttccagcg tatgccctca taggtcgtga atgcaattgg
    31501 ccaaggacgc attccgcgta cttggttgtc aatttcttct gcagttttat gccaatcgat
    31561 tgcttcttgt tcccgtgtga tgtttggcga aaaagttgct tctgactcgt cttgaggtac
    31621 tggtttttgt ccatccaaaa tattgggcaa tgtttctagc aatagctttc ttcctaaaag
    31681 gctaagcttt tcaaacatcg tccctacatc atcttgttta gtgattggta tgctttcttg
    31741 cgcatagatt ccgcctgcat ccattttttt gatcatttcc atgatcgtta caccagtttc
    31801 tttctcccca ttcatgatgg cataatgaac aggcgcacct ccccgatatt taggaagtaa
    31861 agaagcatgg acattgattg cccctaattt tggtacttgc aataactttt caggcaagaa
    31921 ttggccaaat gccgcagtga cgatcacatc aggcaccaat tcaatgattt cttccatttc
    31981 tggcgaaccg gagattttct ctggctgcag cacacggata ccgtgcttca gagccgcttt
    32041 ttttaccggt gtcggcgtaa ttactcgttt ccgcccaact ggacggtcgg gctgtgttac
    32101 cactgcctgg atctcgtaac ctgattctat cagcccttca agaatcggca cagaaaaagc
    32161 aggtgtgccc ataaatacta gcttagtcat caagatgttc ctccatatat tcttcaagtt
    32221 cttcttccgg gatctgctgt atcattttct caatgaacaa gataccgtct aagtgatcga
    32281 tttcatgctg gaaggcacgg gctaaatagc caaaagccgt cacttctatc tcttctccgt
    32341 ctcgatcata ataacgcacg gtcacttcat ctgctcgctt gaccgttcca tagacatgcg
    32401 gaatactgag acaaccttct acgtcaaggc tttcaccttt tgcttcgatg atttctgggt
    32461 taatcagttc aaatttctcg ccttcatcta cttcgatcac agcaattctc ttgttttgtc
    32521 ctacttgagg agcagcgatc cctattccgt cattcgcaat cattgtctca tataaattgt
    32581 ctaataaagc gattgtctcg tccgtgatta catcgattgg ctgagcagtt ctttttaatt
    32641 tatcattagg gtggatcaat ataggatagc gcataatttg gccctttctt aaataaagtt
    32701 taatggttcg ttgtcaattg ccacaaaaag accttgtcgc tgttctttct ggcttccatt
    32761 caaaatttca tccaaaacat gaggaagatt cggttcatgt ttatatttga tgattagttg
    32821 ataataatat cggtttttca ctctcaaaat catgctgggc gttggcccta atagcaagct
    32881 ttgagggctt aacacttctt ttagctgatt ggcaatctga aagattttct ttgccgctac
    32941 ttgttcttca ggatggctgg cggttatttt cacagtaaag taataaggag gatagcctcc
    33001 acgatgccgt acatgcattt cctgctgata aaactgctca taattttgtt ttttagccaa
    33061 ttctatggcg taatgttgag gattgaatgt ttggatcacg acttcgcctg ctttttccgc
    33121 tcgccctgct cgtcctgaaa cttgggtaag caattggaat gtatgctcac tagaacgaaa
    33181 atccggtaaa ttcagggagg tatcagcatt caacacccca actaatgtca cttctggaaa
    33241 gtccaaacct ttagcaatca tttgtgtccc taataatata tctgcttctt ttgcaccgaa
    33301 tttttgtaaa atctgttcgt gtgccccttt tcttcgagtg gtatctacat ccatacgcaa
    33361 aatcctagct tgcggataaa gttctcggag ttcctcttct actttttgag tacctgttcc
    33421 atagtagcgg attttattgc cgccacaatt aggacagcga ttgggaatag gttcttcatg
    33481 tccgcaataa tggcagcgca ttgaacgtgt atccatatgc agtgtaagag agatatcgca
    33541 attaggacat ggaagaacaa atccacagtc cctacacatc acaaaagacg aatatcctcg
    33601 acgattgagc agtaggacag tttgttcttt tttgtctaat cgattttgta ttttttcctg
    33661 caaattagca gaaaaagtag aggtccgatg attctgaaac tcttcacgca tatctacgat
    33721 ctcaatagct ggaagctgtg cagctgcttt ggctcggtgg tttaactgca ataactgata
    33781 aacgcctttt tgagctcgtg ctcttgattc taaagagggc gtcgcgcttc ctagaactat
    33841 tgggcaatga tgatatttac tgcgccaaat tgctagatct ctcgcatgat aacgcggtgt
    33901 ctcatcttgt ttgtaacttg attcatgttc ttcatcgata atgatcagcc cgatattttt
    33961 cagcggggca aaaatagcag atcgtgcgcc tactactact tgcgcttctt cccgctcaat
    34021 cttgcgccat tcatcatatt tttcaccttg ggaaagtccg ctatgtaaga ccgcaactga
    34081 ttctccgaag cgtcctttga atcgctcgac catttgcgga gtcaatgcga tttcaggcac
    34141 taacataata gccgttttat tttctgacaa aacatcagcg attgcctgaa gatatacttc
    34201 tgttttcccg ctgccagtga ttccctccag caaaaagacc tgatcttttt gctgctgacc
    34261 tgctgtgatg atttgttcga cagcattttt ttgttctgca ttcagttcca atgccgtcgt
    34321 ttggtcaaat actcggtctt tataagggtc gcgataacgt tctgattcta taaactccag
    34381 ccagcccttt tcttttcctt gattcaagac agcagtactg attcctttat ttttgaaata
    34441 agcaattggt tcttcttggc tcagttcaga taaacacaaa agaagttctt tttgtttctt
    34501 ggcattttgc cgtaattttg cccattcttc ttcgatttgc ttttcagtta acaaagaacg
    34561 gaccaaacga atcgttttta ctttatttcg tgtatggact tcatatttga tatctactaa
    34621 ttgctcttgg cgccagcgaa tcaattgaga aaggctgcct tcttcttctg cttccttcca
    34681 ggaaatcact tctcgctgat caaacaatac ctgaacttct ggtgtgtctg ccaaaggata
    34741 gatcaattta tcatattctg ctttcatcac actcggaagc atcgtttgta gacaagtgat
    34801 tttgaatgcg taagtaattt ttttcatata atcagctaat gaaagtaatt cttcattgac
    34861 caccggagca aggtctagca aacgaataac tgccttcaaa gatggattag ctgattcttc
    34921 tgatttttgg atagccataa caaatccttg gacatgacga ttgccattac caaaagggac
    34981 ttctactcgc atcccgactt gcaaagctgt ttccatttca gagggaacca aataagtgaa
    35041 tggctgatcg gtctgcatag taggtacgtc cacaatgact tcagctgtta atgtcatggt
    35101 tcgtttcctc ctttttttgt cttttcttat caagcgacaa aaagttcctt gcctatttta
    35161 ctagagatcg atggatttgt cttatcttct gccaaatcct aacaaaaaat taacagcaga
    35221 taagaaaaaa aagaactgtg tcaaaaagtt cagacacagc cttttctacc agacaataag
    35281 tggcgaatgt ttgaaaagga aacagctggg tttgcttttc tttttagatg ttcgctctat
    35341 ttttctttat tacatttttt gctcttcacg gatacgtgat tccaattcgt gttgttcacg
    35401 ctctttttgt gcttgacgtt cctcttcttc catcttcaaa cgttcacgtt ttaattcagg
    35461 atgtggatca ttgactacat ttcctgcatc gatttcttct aaagcttgac cgacgctttt
    35521 tactgaatca aaagaatcta gagtaggctg tgcacttgca tccaattcat gcgcgcgttt
    35581 acttgctaaa atcactagag aatattttga atttacacga tctaatagtg agtcaattga
    35641 aggttttaac atcataagac tacatctcct ttaacatttt aatatattta ccgattacgc
    35701 gatctactcg aaaatgttca ctggcaataa tgtttttgat tcgttcaact gctagcggca
    35761 cttcatcatt tacaacagca tagtcgtaaa gagccatcat ttcgatttct tcttttgcaa
    35821 ctttcattcg tttttcgatt acttcatctg catctgttcc tcggcctacg atccgtgatt
    35881 ttaattccgc taaatctggc ggagtcaaaa agatgaatac accatcgggc actttttctt
    35941 tgacttgttt tgctccttgg acttcaatct ccaagaaaac atcttttcct tcatccaatg
    36001 tcttgttgac atatgacaaa ggagttccat aataattccc gacatattct gcgtattcca
    36061 gcatctctcc agcttcgatc attgattcaa actcttcttt gcttcggaag aaataatcaa
    36121 cgccttcgac ctccccttca cgcattttac gggtagtcat tgagatcgaa tactgaaaat
    36181 cattatcctc actctcaaaa attgcttttc gtactgtgcc ttttcctaca ccggatggac
    36241 cagacaacac gattaataat ccacgctctg acatgacgac gtcctttcaa ctagtctttt
    36301 tgtacttatc gtttattttg cacttttttt ctgcaacttt caaggttatc tttaattata
    36361 gctagaaatt ggtaaaaaag ctaccctgta ccaagaggtc gtaaaaaagc tgtcctgcat
    36421 caagtaataa gaacagccaa acataaacag cttctcatgt ttttcgtttg gttggggtta
    36481 ttatcgcaga tgcaagcttt tgaacgccgt gtataagagg tcgtgaagaa gccgattagt
    36541 ttcgagtatg aagaaaaatt ttgtgaaaat agtttctcac atttttgcat aaatttggct
    36601 taataccgag aaaatggttt ttgaacatca cttattcaaa ataaaaaaag attgtgacac
    36661 gaattttgtc acaaccttta aatgtattcc tagagcaaag aagctaagcg aagaaatcca
    36721 attctgttta tttattgtat ttctttgttc agcatccttg ctaaaagccc atattggaca
    36781 aagtattcac tacacccatg atctcatctt ttcgagaacg tgctttttct gtcggatctt
    36841 ctacctcttc tgtgtcaatt cgaacaataa atttccgatt catcgtcacg taagcaccgt
    36901 cgttgatcaa aataaacagt tcgttctcat tatagtctgc acaggcatct ttccatacgt
    36961 caaagccgtt tttttcagaa gggatatccc gtttaaccac agtttttcca cttaattcgt
    37021 ggaacgttac gtcataatat ttcattatct ctacctcttt cgtcattcaa tattttgtac
    37081 ttgttctctg attttttcta agatcgtctt agactggacg acttgatttt taatttcgat
    37141 tgcatttgat ttggaaccga tcgtgttgat ttcccgattc atttcttgga tcaggaaatc
    37201 taattcccga cctacaggac attgtgcttc gataagttca tctagttttt gtacatggat
    37261 cgccagacga tccagttcct cgtgaatatc tccgcgttcc aacaagatgg ctagctccgt
    37321 caacaaccgt tgctcatcga ctttcgctcc aagaaattcc tccagctttt tttgatacct
    37381 tatttgaaat tccttttcat agatttctac aaaactatcg agttttttta gtacttcttt
    37441 gaattcttca gtattctttt tcaacactaa agctaaagct tgaccttctt tttctcgact
    37501 cgcctcaata gaatcaagtg cgcttttcaa tgtatctaga gctaactgtg ccaattcttc
    37561 catgctctct tccggttttt cttctaccgt tacgaagttt tcgtccagca cgaagcgttc
    37621 cgccatccga ctaattgaca cttgattttg actaccgtat cgttgttgaa ttccgtctgt
    37681 caattgagtg ataagtgaat caatcaattc ccagttgatg acgatctgtt tttcgttttt
    37741 gccaatataa gctagattca caaatacttc gattcgaccg cggcttaact gctgtttaat
    37801 aagctgacga aaatcgtttt caacaaagtt caggatttta ggacttcgta tttgaacatc
    37861 tagaaaacgc tggttgacac tttttatttc aatatctaac tgatacgctt ttgtttcgcg
    37921 gatggctttg ccaaaaccag tcatactttt cattcgacag ggtccttcct cattacatat
    37981 tttctattgc tttttgcagt tgttcaaact cttcgttcgt caatgtcagg cctttcccca
    38041 ttttttcatg gtctggcgcc caatctcgaa gatcgaattt tggcgggcga ccattccagc
    38101 tgactaggtt cagttcttta cgccacccct tgttgttttc tgacaatata gcgatttctt
    38161 ctacgatttc atatgaaaat tcttgtgcca tggttgttcc tccttgagat aatataaata
    38221 taggatcagt aatgtgtcaa ctggttgctt aagcaattca tgctgcaaac gatccttgcg
    38281 ttttccttgt agcagataat caaaataaac agttttcgtg cgctcatttt gtattttttg
    38341 ctggtatttt cgataccttc gccattcttc agtacttaat tgaccaattt gtgccaataa
    38401 atcatccggc atacttttta tatcttgttg gcagatcatt tgaatcatca tgtctacttg
    38461 atagatttca ttgggcagta aaaaatgttt ttttgctaaa agttctagca tcgccaatcc
    38521 gcatgtctct ggtacgaccc tgttcttata taaattacgc agtttttgcc aaaattttat
    38581 gcttttgaaa aaagataatt ctaactgaat ttcttttgtt aagtaagaca aaaatcctcg
    38641 ccagtatgtt cttgcaggtt taacagaatg aaatgtatac cagttcccat agtaatagcc
    38701 taatcgtttt ttcatttcca gatagcctaa ttgtaaattt aattggttcc tttggctatc
    38761 aaaaagcaga aagctgccta gtgtccacaa tgtttgacat ttccaatgga taaaaatgtc
    38821 tggcatacga atttttttcg ctgggcctgg cccttgcaca tctacgacaa atgcctctgt
    38881 tgctcctttg ttaatcgcaa tatcaatagg tattttgttg cgatacccac cgtctgcata
    38941 tttatttttt ccgatctttc gataagccat agcgggataa aatgaagcag aggcgagtat
    39001 ccaatctggt atttcttctg tttttgtctg ttggatatca gtcactactt ccgctagttc
    39061 tggcagttta gtagacaccg tatataaacg tattttggga ttatgtttga gtaaggacaa
    39121 atccaaattg tctttgacca tcttttccaa tggagcagaa gaaaccccgc cttcaattag
    39181 tgctgttttc gtcatttggc gtctttctcg atagaagcgt tcacgaaggt cttcaactgc
    39241 agccatttct ggtaacgcaa gcacttgtct tgtcgacagc tttttccata aattcacagc
    39301 ttttttcata tctccttgta aaatcaatgc gccgttcaac gcacctaccg aggtacctgt
    39361 gataatctca aagttgatat catgttcctt cagcgcctgc cacacaccaa tctgataagc
    39421 accgtgcgct cctcctccac ctaaaacaag tgctgtatga tagaccagct ttttatttaa
    39481 ttgtgtggtt ccttgatagc cgtttttatg aaaaatacgc aaccattctt ctgatagagg
    39541 agattgaaat aaaaaacaac agttttcttt aataaaaaaa cgagcgcaag cttccatata
    39601 ccgaaaaaat tttttccatt caaaagtttc accttcaatc aacagattat taaaaataac
    39661 atctcctcta cttttagcaa tagtaaaata gacggtatat tttttcgata ctgctttaaa
    39721 agcacattgc ttttttgcag aacgccaaaa agcgtctcta ctttcttgat gactttgaaa
    39781 aaatggaagg ggttgttttg cttgctggat aggcgaatac agcgacattt tctgtgaaaa
    39841 gtaaactttt tttatctcca tcgcgctctc ctttttcttc aagtatacca gtacgtcata
    39901 aaaaggtcat gagtctcgta ttcgactttg tagattccat aagaaaacaa ttcataaaac
    39961 ctcctttaaa taaaaaaata caaaaatcac aaaaattaat tgaaaatgag agtgttttca
    40021 atgaaaacgt gattttgtaa tggaatttta aaataaaaga aacaagcttt tttaatgcaa
    40081 atgttgtaaa ataaaagaga ttaagaggaa ataagaggag gaacatgatg actgagtcag
    40141 tttatgtaca tattgatacc acaagtaatg ctgttttaac aaaagggctg actgctactg
    40201 actttgcaaa cagtatcgtg cattttcctc aaaacttgct cttgcttgat ccatctgctt
    40261 ctgctggaga atatgaatcc catacagggc tgaaagtaat ccgtggtaca gaaaatattc
    40321 agcgtttctt ttcctcttct cgtaacaggc gtggattcga tgaattgaag tggatcgact
    40381 ttactgattt aacgatgctg aaagaattga cacctttaga aatttcagaa ttattatatt
    40441 ttggtcatat gaaaacacat cttcattcgc cgttttttta taaactacag aataattttg
    40501 tatacttcga tcttaatgat cagctgaatc ggatttatta tcgctattta gatgaatttt
    40561 ataggatttt tgctagtaaa ttaagttcga tcttgtcaga taagatcaat gtaaaaaaat
    40621 cttttttcaa aaaagaaaca cctgttgaaa aaatcagtgt ggaattattg aaagaaatgc
    40681 gtaatttgat gcaggaaggg atcatttttt cttttgatca agttggtttg atcgatggta
    40741 aatatcgtat cccaatctat gtgattgaag attatatttg gaaattaaaa ggcacccggt
    40801 atcgagaaga ggaaatcatc gctactttaa tctactctgt caccgatcga cactggcaat
    40861 tggtagaaga tgccgatctt tcttatctgc cattgaagta gatctatttc ttatcaaaaa
    40921 ataaaaagga aacaagaaac taggacatga ttctgtctca agtttcttgc ttctttttta
    40981 tttacagctc ctgtcgttta tctggcacaa aaatcgaagg agtcgtttgt tggatcccta
    41041 ataaaacgat gatcgttaca atagctgtac tcaacccgct ggcaccattc attacgaaag
    41101 aaaagagcca aggattcatc ccccatagtg catacgctcc ccagaaaacc actcctgcaa
    41161 taaaatgcca aaaatatctg gaaagtgcgc caatcaatgc accaaacacg atgctttttc
    41221 taatttgttt cgtattatcg tctacatagc ctttttggac atttgaagcc atgagccctg
    41281 ctgcgcctgc aaaagtatag gcaatcgggt actcaatcaa cacttgaacg acacttaaat
    41341 aataaacttg tcccaacgga aaatgtagga tgccccaaat gaaacctgcc agcatccctg
    41401 cctttgtccc tcttcttaac gcaaaaagag tcaatggaat ctgccctaat gaaatagaaa
    41461 aactgctgcc gatctggatc ggaatcaacg acaacaccat cgctaacgct gcaacaatcg
    41521 ttccttctac ccaaactcta ttttttccca taaaaaaact tcctcctttg aataaaaaag
    41581 tcacaaagga ggaagcagct ttcgaaaata gtcaaacagc tgtttattca caattcctac
    41641 gctcgcataa ccgatacagg tacgaagggt ttagaaatag attcaatctc agcccaattg
    41701 gactcccctt tgtgagttta tttattattt attttttgtt tcaaacaatg gactaactgg
    41761 tttgttttca tggatacgtt tgattgcatc tcccattagt ccgccaacac ttacttcatc
    41821 gattttgtcg attttacgat cttctggaag atagatcgag tctgtaacaa ctagacgctc
    41881 gatagctgaa tcttctattc tttgtaaagc agggccggat aatactggat gtgtacatga
    41941 agcatacaca ctagttgcac cagcttcttt caaagcattg gcagccaatg tgatcgtacc
    42001 tgctgtatcg atcatatcat cgatcagtac acaagttttg cctttgactt gtccaatgat
    42061 attcattact tctgcaacat ttgcttttgg acggcgtttg tctatgatcg caatcggaga
    42121 tttcaaaaat tccgctaatt tacgtgcccg tgtgacacca ccatggtctg gtgaaacaac
    42181 gacaacatca tcgcctttga ttcctttttc taagaaataa ttggcaataa gtggcgcacc
    42241 catcaaatga tcgactggaa tatcaaagaa accttggatt tggactgcat gaaggtccaa
    42301 agtcagcatt cttgttgcac cagctttttg aatcatgttt gctactaatt tcgctgtgat
    42361 tggttcccgt gcacgtgctt tacggtcttg acgcgcatag ccataataag gcatgactac
    42421 gttgattgtt tttgcacttg ctcgtttcag tgcgtcaatc atgatcagca actccatcaa
    42481 gttatcattg actgggctgc tcgttgattg aataacatag acatgcgatc cacgaatact
    42541 ttcttcaatg tttacttgaa tttctccatc actaaattga gtaacagatg attttcctaa
    42601 ctcgacgccg actgctgctg caattttctc tgctaatggg cgattggaat ttaacgcaaa
    42661 aatttttaat cttgggtcaa agtaatgttt tgacatgggg acctccactt tctttttcac
    42721 aactctagaa ttctacctaa taaatagtag tcatattttt taaataaatc aagtgatttt
    42781 gcaaaagtct tagtttagat aagggagttt ttttgcatat ccttctttat tgacttgtct
    42841 tgctctcgca attgccagcg catattctgg aatattgtct gtaattgttg acccggcagc
    42901 aatcgaactg tttttagcta cctcgacagg tccgatgata ttcgtgctag aaccaataaa
    42961 gctgtggtcg ccgacagtcg tatgatgttt gttctttcca tcatagttga cgaagacaac
    43021 accacatccg acattgattt cttctcccag cgtagcatca ccaacataag tcaagtgacc
    43081 gactttagtt cctttgccga tttgagcatt tttcacttcc acaaagtttc cgatatggac
    43141 gttttcgcca atttcagctt ttggtcgtaa atgtgcataa ggtcccacat ctgcatgttt
    43201 cttgacatgg ctgctttcaa tgactgagtt ttcaatgacg acgtgatcct caatcctact
    43261 gtctacgatt tttgaatgtg acccgatgac acaatcagaa ccaatgactg tatttccttg
    43321 gatttgtaca cctgcttcga tcaatgtgtc tggaccgatt tctacgcctg catcgatgta
    43381 tgtcgttgct gaatcgacaa agcttacgcc attgaccata tgcatctggt taattcgctt
    43441 tctcatgatc tcatttgctt tagctaacgc gatccgatca ttgactccca ttgattcttc
    43501 aaaatcatcc gtttgataag cagcaactgt atggccttct tcttttaaga tttcgatgat
    43561 atctgttaga tagtattcac cttgagcatt gtttgttcca actttgctta acgcatcgaa
    43621 caaagcttcg ttgtcaaaac agtaagttcc tgtattgatt tcttgtacaa gagcttcttc
    43681 tggtgttgca tctttttgtt ccacgatttt ttctacgatc ccaatatggt cacggatgat
    43741 tcgtccatat cctgttgggt tttctgcttg tgccgtcaag atcgttgcac ttgcattttt
    43801 tccttggtga tattcaaaaa gattgttcag cgtttcagta gtcaataatg gtgtatcgcc
    43861 actgataact aacgttgttc ctttttttcc ttccaagaaa gaagcagctt gcaaaacagc
    43921 atgtcctgtt cccaattgtt ctgcttgtaa cgcatattta ctgcgttctc ctagttgtgc
    43981 tttaacttgt tctgctccgt gtccaacgat cgtaatcact tcatctggtt tcgtttcact
    44041 gacccgatta atgatatgtt ctaccatagg tttaccagaa acgggatgta aaactttata
    44101 taattttgac ttcatgcggg tacctttccc tgccgccaaa ataattgcat aacgtgcgtc
    44161 caactgcgtc actcctaaat atagtttgct gatttcagtt tatcccagta tacccatttt
    44221 ttcaacaaaa caagtgattt tcttttatcc cagcgttttc tggataaaaa aatagataga
    44281 ccataacggg cctatctatt tggtaaccgg tgctctcctg ccaactcctc ggtcacaagt
    44341 cacactactc ataaaacatg aaaagctgtt ttttgaaatc gtttcttgtg acttagagtt
    44401 aaacggtagg cttacaacct cttcattaaa cgtttttcaa tcagctgacc ttcggtatta
    44461 gctcaataaa cggcaaaata tgaggagcaa tttttccgtt tattgagcta atactcagga
    44521 caggacgctg atttcacaac ctctagataa acggtgttca aaagccagtt tctcggtatt
    44581 aagccaaatt tatgaaaaaa tgtggaaagc cattttcaca aaatttttct tactactcga
    44641 aactaagcgg ctttttcaca acctcttatt ctgaaaaata atttcctggc acaaccgtaa
    44701 tatttttcgt ttgagtatct acatctttga cataaagcag tgacgtataa tcatcgatgg
    44761 cgcgatgacc gttgaatttt gattcggcaa atacagtgat gccaacaagt tctgattcga
    44821 attcttcaat caagctcttc attccgttga ctgttccgcc gcctttcatg aaatcatcca
    44881 ctacaaggac acgtgaacca cgtttcaaac ttctcttaga cagttccatc ttttcaattc
    44941 tttcagaaga tccagacaca tagttgacac ttactgttga tccttctgtt atttttgagt
    45001 cccggcgtac aataacgaat ggcgcattca gataatagga cacagcttgg gcaataggta
    45061 cgccttttgt ggctacagtc attacagcat cgattttttc accaaggtat ttagaagcaa
    45121 tgattcttcc aacttgacgc agcagttcag gttctcctaa caaatcagag agataaacat
    45181 atcctcctgg aagcagacgg tcttgttctg atagacgttc tgctagagat tcaatatatt
    45241 ttttcgcctc ttcatatgaa atttcaggga tgaacaatac accacctgca gcacccggga
    45301 ttgtttccaa ggttccatac cctcgttctt taaatgtttt cttgatgatt cccaaatctt
    45361 cactgataga agatttagca gattcataac gttcggcaaa gcttgttaag gaaatcaatt
    45421 catgcgggtg attcaataaa tactgtgtca tgtcaactag acgttcactg cgacgtactt
    45481 tcacctattc caactccttt taagaaattt tatcgtttta cattatataa gtttttcttc
    45541 aaaaattcga gcattttatg aaaaaataag aaaatagttc ggtatttatt aaaataaaaa
    45601 gaagcctata aaaaattttt cgtttttata aggcttcttt tctttataat ttagttattt
    45661 tttcttctga aggcaaccaa tattcgtttg atgatattta caatcaggaa caaagcaata
    45721 aagactaatg tgattgttgc tcctggaggt gtatctagat aaaacgagct agttagtcct
    45781 gacagcatcc ctagaaatcc tacacaaaca ctgatagcaa tcacgacatt gaagcttttg
    45841 cctaatcgca taccgattgc tgcgggaaga accatgattg cggatatcaa aagtgcaccg
    45901 gcaatcggga tcatcacagc aatagccaca ccagtaatca cattgaacat catcgacatc
    45961 aaatgaacgg gtagcccatc cacgtgggcg gtatcttcat caaaagtcag aacatacatc
    46021 ggccgtttga ataaaaagaa caatataccg atggcaacga ataagattcc taaaaagatg
    46081 acttgctccc atgtaatggt cacgatcgaa ccaaacagat aggattggat acttgttgct
    46141 gaattccctc cgctcaaatt catcaatact aacgctagcg ccaaaccacc agccattaaa
    46201 atggcaatgg agatttctga ataggttcgg tagatcgttc gcagatactc caatatcaca
    46261 gctgctaata caacgactag catggtcgta agtgtaggat taaggttcaa aaagaatcct
    46321 aacgctaccc ctgctaaaga gacatgagaa agcgtatcag ccatcagcga ttgtcttctg
    46381 atcactaaaa acacacctag catcggggcg attccggcaa tgaagatagc ggcaagaaac
    46441 gctcttctca tgaattcata tgaaagcaac gccattgaga atcctccttt ctcaccagtc
    46501 ggatctgtct gtccgcatac tgtttgatat cttcatgatc atgggtgatc attagaactg
    46561 atttcccatg gacatgcgca ctatgtcgga gaagacgata aaattcattt ctggattctt
    46621 catccatacc tgttgttggt tcatcaagaa caaataagtc agggtcagta gcaaaaatac
    46681 gcgctaaact gattcgctgc ttttgtccgc cagacaattc acctattcgc cgatttcgca
    46741 tatcccacat ccctacagct tctaaagcac gctgtacatg ttgatgatct ttttcagaga
    46801 gacgcttgaa ccagcggcct cttggatatc ttcctgaacg gactaattcg atcaccgtac
    46861 taggaaaacc tgcattgaaa gatgcaactt gttgaggaat ataaccgata cttaattttt
    46921 ttccttcttg atttttctca gcaatcttta tcattccttt tgaaggtttc agtaatccta
    46981 acgatgcttt caccaaggtt gacttggctg ctccattttc tccagttaaa atgacaaatt
    47041 cacccgcatc tacatgataa gagacatctt ctagtacagg ttcatcatca tagtaaaagg
    47101 tcaaatcaga tatttcgata taacgcacct tacaacctcc attctaaaac ttaattgata
    47161 ctttctttta aagctttcag atttttttcc atgacagaaa tataattttc gcctgctttg
    47221 atttgttcat tagtcaagct ttctaaagga ttcaacactt ctagcttcac tcctgtttca
    47281 ttcgacaatg tctcagctac cttcgaagag gcattttctt caaaataaat cactttgatg
    47341 ttgtttttct tcacaaattc ttttagctca gctaagcgac ttggtgtggg ttcctgatct
    47401 ggtgaaacgc ccgaaatcgc tacttgtttt aagtcgtatt gattcgctaa ataagcaaaa
    47461 gcagcatgct gagtgacaaa tgtgcggttt gttgcatctt ttagctcatc ggagtatttt
    47521 tgatccagtg cttcaagctt tttgatataa gcatcggcat tcttcgtaaa agtttccttt
    47581 ttatctggat atttttcgcc taattcttca gcaatcgttc tgacttcttt tatagctaat
    47641 accggatcga gccaaacatg tggatcgtat tcatgtgaat gaccatgccc ttcttctgat
    47701 tcttcatgtt cgtctgcttc ttgcgattct aaacggtcga ttcctttagc tgcttcgatc
    47761 atcaaggtct gtttgctatc cactgaatcc tttaacgaat ccacaaaaaa ttccatgtct
    47821 gaactattat acacgaaaac atctgcatcg gaaatttctg ctctttcttt tgcacttggt
    47881 tcgaaatcat gcggctccgt tccagcaggg atcaaaagtt tcacgtttcc ttcatcccct
    47941 acgatctctt ttgtaaaatc atacatcgga taaaaagtcg taacgatcgt caaatcctct
    48001 tttttgtctg cttccttgtt cgtatttcca catgctgcaa acagtaaagc acctatcatt
    48061 accgtagctg tcaaaagata ttttttcatt tatatgctcc tttcaatgaa caaatcggaa
    48121 ttttacgatt tattaacgtg aactaatgta tcaaaataaa aaaacacagt caatagaaat
    48181 ccatcaattt ctgatttaag catgtatatt cttgattaaa tcgtaaaatg gatgagttgc
    48241 tgctcatatc tagccatttc actacaataa aaaactgaag aataccattt taggattcct
    48301 cagtttttca tcacctattt tacttcttat attttattgc agggttcgta ctaaataaac
    48361 ttcctcacaa aaacctttta acccattata tactctctgc gctcttgaat aatgttgaca
    48421 caaggcaaaa acggttggtc cgcttccact catcaatgca gcatctgctc cgtacttgat
    48481 catacgctct ttgatttgat ggatgactgg atgccgcttt cccgttatat cttctaaact
    48541 gtttcccatt tttttgatca tctgctgata atcttgctct cggatggctt cagcaagtcc
    48601 gtggatgtct tgatgttgga tggcttgcgt atctacttct ctaaacactg tacgtgtaga
    48661 gacactcatt cttggtttga ccaacacaac ccagcactgt ggcatagaag gtaatacttg
    48721 gatttcttcc cctttgccac cgacaaatgc cgtacttccg tagacacagt aaggaacatc
    48781 tgtaccgact tccaaaccga tttctgccag ttcttctaac gaacagccca gattccataa
    48841 ttggttgatc cctcttagag cagctgcaca gtctgtactt cctccgccta atccagctgc
    48901 tactggaata ttcttcttaa caaagatctt gacaccggtt ttgatattgt atttattttt
    48961 tagcaataaa gcagcttgat aaacattgtt ccgttcatct accggtaaaa atgctttatt
    49021 tgtttctaca atgattttgt cttctgttat ttcttcaaaa aatagatgat ctgccaagtc
    49081 tacgctcgac atcaccattt ccaactcatg atacccatct tgccgtctat ataatacatc
    49141 cagtcctaaa tttatcttgg ctggcgcttt ttcaatcaat tccatcctct cacccattcg
    49201 aaaagtctaa gtcgcaagta ttctatcata gggaaaaata aaagtatagc ttatgtctgc
    49261 ctagtggttg attttgtcat cgtttcaaca gctttcacag aattttctct tcataatcca
    49321 aacaagttct agtgattctt ataattctgt gagcacttct tctgccaaac tcggaacatt
    49381 tcctttttct tttcctatca gactgagtag ctgcatggta gcaaatccga aattacttcc
    49441 tttcctataa gcaaaataac gtccttccca atgatcgaca tattttaatt tcttttcata
    49501 agcagactgg aaggaataga aaaaattacc ataattatat acgatatgca tgactttttc
    49561 ttgaaagaaa gaaaaatctg tttctccaac attagctaat ggagctaagc ctagattggc
    49621 ttccgagtag cccattttct cgtatacaat aaacagattg gctaacagat agtcagctaa
    49681 ttcctcagat tctttaggta agacccgcaa caaatcatat cccgcctgct tcttcgtcat
    49741 cggctgagcg gtgatgaagc caacgacttt ttgatcttta cggacaatac cgacaccgct
    49801 agataataca tatgatttat caaatcgtcc cacagagaag tatttttctc gtgcaccttg
    49861 aagccatttt tgtgaaactt catttacagc ttgatgtaat tcttccggca gttgatcgta
    49921 ccaagtaaaa tggtatcctt ctttcatcaa acgttgatat tcaagttgct gactcagccg
    49981 agacaagtct tctgttgcta gatcaacaat ccctgcttca cctactttcg tgaagtgaaa
    50041 acccaattca tgaagcatca ctacgtagct ttctgatatc ttataaaacg caagctgata
    50101 gcctaaacaa tctgcttgtt tcataaactg attcgttgct gcccgcatca ttttaggatt
    50161 gccaactgga tctcctaaaa caaagcattt gtttcctttg atctgataac caaaaacgac
    50221 ttgatcttgg tcgtcttctt ggtaataaaa ataactgtaa cctgacaagc gaagctgatg
    50281 gcttgtagct gtgcctccgt atgtttccaa taaacggtca aaacggtctt tttcgtactc
    50341 actgccaagc ttcgtagtat cttcagctaa atattgataa agcgccacta aagctagcaa
    50401 tgagatgccc aaaccaataa gccctgagaa ccacacatca tctgaaggaa acaaaataaa
    50461 atgatttcct gttattcgac cgactaaaaa gcgtccgctg tgatagcctg caattgcgta
    50521 aacgataaac aaaaagccga acaagctagc atcaaagatt atagctcccc aagaataaac
    50581 gaattttgtt cgataaaatt cttttctgga taaccacaca gctaacagaa tcaagacata
    50641 taccaatatc aactgccaag ataacgtacg tgtgattgta tttaaaatac caaaagatag
    50701 taaagcaatc gtaggcagaa atgccttttt gacttttact gaaagtgctc tagcaaggcc
    50761 gagtaataaa aagccaacca atagattcac tgtctgatct aaaaaattga atgagaacgg
    50821 caataatact tgaaatagcc gactgattgc agacagatta gtgattgttg atagaagtac
    50881 catcatgatc cccgcaaaat agacagcact tacgagcacg atatgcgcaa ccttttggaa
    50941 aaacagtcgc ggaatgttat ctaaaaatcg attgattttg actcctgtat gtgtgatgaa
    51001 caatagaagt cccgtcataa aaggtagaac ataataaaac aaccgataat ataatagcca
    51061 aactactgct acatcttgcc gaacagacaa ttgactcatt cctaagatca tcaaaacgtc
    51121 aaaagtcccc attccacctg ggaccatcgt cagcattcct atcaatgtag caatcatgaa
    51181 cataggatag atcgaaagca tcgaaatatc tattctcatc aacttgccga tgatcaaaaa
    51241 taccgcaagg gctcccgtcc attgtccaaa ggatgccagt agcagaccaa gcaagccttt
    51301 tggataaaac tcgaagaaca atgtctttct ctttagataa gcaaaaaaga aaatgactgg
    51361 tgctaaaaaa ctaccgccga aaagccagat ccaatagctt cgaaaaatac tttctgactg
    51421 aataaaaaag acatcaataa atgtaagaaa cgaccataca gacaaaccag tcagcataaa
    51481 tagtgcgact tttgatacag tggctaaaac catttttcta tttgtctgct ttccataaaa
    51541 actagcccgc agacttgctc ctaccacacc accaaaaccg gcgagattgt tgatcgtgtt
    51601 tgttacccac gcagcaagaa gaaactcttt tctttccatt tttggttttc cttgtttttc
    51661 taagactctg atcgtcaccc aatcatacaa caacatcgga gtgacaccca gcagtccagc
    51721 cagaatcatg agcaggatcg tcatgcggct ttgttgtccc atcctttgcc aaatatcttg
    51781 ccaactcatg ccattagcaa tatttgcgac ttgatttgcc acaaagacta acacggagcc
    51841 gaaaaaaatc agttttaaaa tcagactatg ttcctttatc cattgcagca tcaagtatcg
    51901 tttatttttc acattttccc attcctaact tgtatacttt tgtgtcatac cccaatgtta
    51961 tcttatttat tttaattttt ccactttaga cctgttcttt gcttgcgatg atagaaaaag
    52021 aaagatatcc taatgctaaa ggagaggata acatgaaagt aggatttatc ggcacaggga
    52081 atatggcaca agctattatt gatggtttat taaaaaaagg aacagtctcg aaagaagagg
    52141 tgttcgtttc cagtggacat tttgaaaatg cacaaaaatt tgctgctgaa actggcgtcc
    52201 atgcatgcaa aagtaatcag gaagttgcat cacaatcaga tatcgttctt ttagccgtga
    52261 aaccaaaaat cattgaaaaa gtattggaag aactaagaga atatagccag aaagtcttat
    52321 tcatttctat tgcttcagga aaatcattaa tagatttaga aacagcgctt gaagatcctc
    52381 aggcctccat cgtacgtgtg atgccgaatg tcaatgtcag cgtaggagca ggcgtttctg
    52441 cgatttgcaa aaatgaagct gccacggagg aacagcttca gcaagctacg atgatttttg
    52501 aagcaatcgg cagcgtctat cctttagcag aatcagattt cagtacattc attggccttg
    52561 ctggcagctc acccgcattc gtttacatgc tgatcgatgc gatgggacgg actggtgtac
    52621 tgaatggttt gtccaaacag acagccactg agattgctgc aaaagcaatt atgggttctt
    52681 gtcaaaaatt cctttcaagt gataaaaatc catgggaact tgtagaccaa gtttcttctc
    52741 ctggcggtac aactgttgca ggtgtagttg ccttagaaga agcaggattc atcccagcaa
    52801 tcatcaaagg aatcaatacg acgatcgaga aagatcttga gatgttgaat aaaaaataat
    52861 gatagcaatg ttttttcgtg ccttacaaaa aaagaagagc tgtggctttt gccgcggctc
    52921 ttcttttgta ttttttatta tttagcataa tcagttgcac gagtttcccg aataacgatt
    52981 actttgatgt gtccaggata atccagttct tcttcgattc gtttacgaat atcacgtact
    53041 aaacgaacag cgtctaaatc cgagatttct tctggcttga ccattacccg aacttcgcgt
    53101 ccagcttgaa ctgcgtaact tgattctaca ccggcgaagc tgttcgaaat attttccaga
    53161 cttcttaaac gacggatgta gttttctaat gattcacttc gcgcaccagg tcttgctgct
    53221 gagagcgcat ctgctgcagc tacaaggaca gagataacag aagtagcttc cacatctcca
    53281 tgatgagaag cgatcgcgtt gattactact gggttttctt tgtacttggc agctaattcc
    53341 gcaccgatct caacgtgaga tccttcaatc tcatggtcaa gtgctttccc aatatcatgg
    53401 agcaacccgg cacgttttgc taattggata tcttcgccaa gctctgctgc taagatacca
    53461 gctaattttg caacctcgac cgaatgcttc aagacgtttt gtccataact agttctgaat
    53521 cgcagacgtc cgatgatctt gattagatct ggatgaagtg tatgagcacc gacttcaaac
    53581 gctgcctctt ccccgtattc gcgaatacgt tcatccattt ctttacgaga tttctcgacc
    53641 atttcttcga tacgcgctgg atggattcgt ccatcttgta tcagtttttc caaggtcatc
    53701 cgtgcgattt ctcttcggat tggatcgaat ccggaaagaa caactgcttc cggtgtatca
    53761 tcgatgatta aatcgatacc agtcagcgtc tcaagcgttc gaatattacg accttctcgt
    53821 ccaatgatac gacctttcat ttcatcattc ggaagggtaa cgactgaaac agtcgtttct
    53881 gaaacttgat ctgctgcgca gcgttgaatc gctaatgata ataagttttt cgctttgcga
    53941 tctgcttctt ctttggcacg ctgttcagat tcttttacca ttagagttaa ctcatgattc
    54001 agctcttctt cagtcgattt catgatgaca tctcgtgcgt cctcttttga taaaccagca
    54061 attttttcta gttctttttg ttgatcttca atcatttttt caacgtcttt ttctcgctct
    54121 tcaattaatt gctgttttga actaagtgct tcttctttac tttcaagtga gttctcgcgt
    54181 ttttctaacg agtcatcttt acgattcagc gtttgttcgc gttgaatcaa acgattctct
    54241 tgagatttta attctaactt actttctctc agctcacttt caacttcaga acggtatttc
    54301 tgattttctt ccttagcttc taacaatgct tcttttttta gagtttctgc ttcttttttt
    54361 gcactatcga tgattccagc agctgatgat tgtgcaccag ctatttcttt ctcgtgacgt
    54421 gactttgcga ccataaaccc taaaccaaga ccgacaatta aaccgatgat agcgaggaga
    54481 atgttgaata ccataaaatc cacctccata ctatcttttt catttttatc atctatacag
    54541 cttctatgat aaattattct aaactcgtca atatgcatct tcgcatatat gtgtacaaaa
    54601 aacatgcaca actttattct aatgtttgta ccccgtagtg tcaactttaa ataaacaaag
    54661 aaacggcttt ctacttattc attaaacgat ggtttttaaa ataaatgaca ctagtttcat
    54721 ataggtaaac ctttaaattg agaaactttt ctattaaatt attctttgta gatgaacaga
    54781 tatttttatt ttatgtaccc actcgtataa ttaaataact cacgatttct ttattcaata
    54841 aaaaaacggc aggtcaagga gagtacctac tcttcagacc agccgttttt gtttatcata
    54901 atttttattc ttctactaaa ggcaattctt cttgtccttt ttcatcttct gggacagcga
    54961 cttcttcacc aataccataa gctgctctaa ctagagcaga aacttctgcc atcatttcag
    55021 gatgattagc catatagatt ttagcgtttt cccgtccttg accaatccga tcttctttat
    55081 aagaatacca agcaccgctt ttatcaacaa tgtctttttc tactgccatg tctagaagtt
    55141 ctccttcttg tgagatccct aaaccataca tgacatctac ttcagcgatt ttgaaaggag
    55201 gtgctacttt gttttttacg actttgatct ttgtacggtt accaacaata tctgtacctt
    55261 gtttcaattg ttctgcacga cgtacttcca aacggatcgt tgcgtagaat ttcaatgcgc
    55321 gtcctccagg agtgatttct ggattcgcaa acatcacgcc tactttttca cggatttggt
    55381 tgatgaaaat agcgattgtt tttgttttgt tgatcgaacc agagagttta cgcaatgctt
    55441 gagacatcaa acgtgcttgt aacccgacat gtgagtcacc catttcgccg tcgatttctg
    55501 ctcgtggaac taaagcagca actgaatcga ctactacgat atctacagcc ccacttgata
    55561 ctaaagcatc agcgatctct agaccttgtt ctcctgtgtc aggctgtgaa agaagtagtt
    55621 catcgatatt cacacctaat ttttgtgcat attgcggatc taacgcatgc tcagcatcaa
    55681 tgaaagcggc cgttccgcca tttttttgta cttctgcaat agcgtgtagt gcaactgttg
    55741 ttttacctga actttcaggt ccatatactt cgatgatacg tccacggggg taaccgccga
    55801 cacctaaagc gacatctaac gcaagagagc cacttggaat tgtagagatt tgttggtcga
    55861 ttttttcgcc caatttcata atagagcctt taccatagct cttttcaatt tttttcagtg
    55921 cagcatctaa ggctgcttta cgatcatctg ccaatacgat aatcctcctt atatttacaa
    55981 atcagagcaa catttcatta tccttatcat atctttttta gtgaaaaaaa gcaagaaaaa
    56041 accgaacaaa tattcgcatt tatcattttc ttaaaagctg ttttctcaaa agatcaaatc
    56101 cttgcataac cgcattatat ctgatagcag cacgatctct ggcaaagtga tatttttccg
    56161 aaaccacgcc gtctttagat gaaatagcga tccatactgt tcctgcagat tgaccttcta
    56221 acgtgtccgg tccagccact ccggtgaaag ctacactgta atctgttctt gctatctcac
    56281 gtgcttgaat ggccatctgc tccacacatt ctttgctgac tgttccatat tctgctaata
    56341 gctccggatc aatctccaga aaaccagctt ttgtttggag cgagtaggta acgaatccgc
    56401 ctggaaatac ttcagataca ccagcaatgt cgcctaatgc ggcttggaag gcgccggctg
    56461 tcaaactttc cgctgctgtt acagtctgct tgttttcttt cagtagttcc actacgactt
    56521 ttgctagcga attatcatcg ccgtatccat aaaaatattc ccctactcgt tcttggattt
    56581 tttcttctaa tgctaaaaga gcttgattcc ctgcctgaac atcatttgtt ttcactgtca
    56641 gtcgtaatgt cacttcattt ggtttggcat atggtgcgat cgttggattg atctgtgtct
    56701 caatcagatc ttttagctca gtgaccagtc gcgattcacc aatcccataa aagcgcaaaa
    56761 ctttagaaat tagtttttct tcagaaggaa aacgttcctc tagtaaagga cgtacttgtt
    56821 ccacaaacat tggtttcaac tcattaggcg gaccgggaag aaggatatac gcatgtgtat
    56881 ctgtttgata aaaagtccct aaagcaagcc ctgtacgatt tggtagagga accccgcctt
    56941 cgataatctg ggactgttgc agattgtttt tggtcatttt tcgatgggtt gtttcaaaat
    57001 atgccaataa ttttttgtat ccttccgtat tttgtatgag agacttaccg aggtgagccg
    57061 cagttgcttc ttttgtcagg tcatcttctg tcggtcctaa tccgccacat aagagtatga
    57121 gttcacttct tgtttcagct agagcaatca actcttctaa acgctgctga ttatctccta
    57181 caactgtttg ataataaact tcgataccta gatcagctag ctgttctgac aagaaagtgg
    57241 cattcgtatt cacgacttgt cctagtaaaa gttctgttcc gacagctatt atttctgctt
    57301 tcattacttc ccgctccctt atatagtata cgctgtattt ttatattttt ttatttaaaa
    57361 agagggcaag gagctgtgac aaaaatcttg tcacagctcc ttgttccaaa taaacagtgt
    57421 tctcctgcca aaacctcggt cataagtcac aatatacata aaacatgaaa agctgttttt
    57481 tgaaattatc ccttgtgact cagagttaga cggcaggctc acaacctctc cactaaacga
    57541 tacttacatt gatcctttga acacaccgct gtttttgatg aagtaatcca cacctgaata
    57601 gatagtaaag atcagacaag cataaagcat gatttgatct actggaatac cgatcaggct
    57661 gaatgggata ttattgataa acagcaagat aatagcaacc atttgtgtag ccgtcttgac
    57721 ttttcccggc caagctgcag ccatgacttc tccatgttcg acaagtagta aacgcaagcc
    57781 tgtgacggct aattcacgac agacaatgat cgctactacc caaccagggg cctttccttg
    57841 gtcaaccaac atgataaaag cagtcataac tagcatttta tctgccaacg ggtccgcaaa
    57901 cttgccaaaa ttagtgacaa ggcctcgcgc acgggcaatt tttccatcta accagtctgt
    57961 gatactagct aaagcaaaaa taactgcacc tactagctgt gtgacagcca gtgtggtgtc
    58021 tcctacgtta aattgtcccc aatctaaagg taaacctaca accaaaatga aaatcgggat
    58081 catacaaatt ctaagtacag ttaatttatt tggtaaattc acactatcga ctcctttctt
    58141 ccctattcta cgtgactatc agcgaagttt ccaccgatat tatttacttt tccaaatgaa
    58201 tttattcaaa ggagtatttt tattgaaatt gatctttttg aattaacgaa gaaggaccgc
    58261 gacacagatt tgtcacgatc cttctttttt atacctacaa gtaaacagat gcgtaaacta
    58321 atttatacga tcattctgcg tattgaagag taaggttcac attttttgga ctctgattgt
    58381 tttcccctgg attaactggt acggattctc cattcgcttt gatcgttgca ttgcttgctg
    58441 caccaatcgt gatggtcgca tttgttgctg tttccggtaa cacggtactc tgtgtttcat
    58501 ttgctgccag tgtcccttga taaacatagg cattgtctac tagcacacct aaccatacac
    58561 gattgacagc agtaaattca agggttacag gcttggtagc gtctgtgata tttactgcga
    58621 tggcactgcc agaatcttct cctgtagcta ttgccatttt cttttcttca cttgattttg
    58681 ttgttgattc tactgtagaa gactctttgg tctgcgtgct ttgctctgag gaagaggact
    58741 cctcgactga tccttctact ttaagcgaag aagctgtgtc tccgattatt ggatcagctt
    58801 gacgatcttg ccaagtcata tagcccacga caacgacaat cgccaaagca accaatccta
    58861 ataaaatgac aggaagactt gtccaaaagc gacttggatg cgattcttcc tgatgcattg
    58921 cttttctaga agtacttact gtttcaggct gcggacgttc agggaccgat cctgtcaatt
    58981 tgcttttccc atcaaaaaca tcgactaaat ggtctccatc ttctcctaca gcttcagcgt
    59041 attgccgaat aaatgcccgc acgtaaaatt taccaggcaa ttggtcaaaa tcatcattgt
    59101 cgattgcttc caaataacgt ttttgaattt ttgtaatctg ctgtaattca tctaaagata
    59161 tttttttatt caggcgtgct tgccgtaatt tttctccgat ggtttcaaaa gccactcgtt
    59221 catcttctcc agtctgtttg attctccgaa gcatctgctg ttgcaacgaa agacgttatg
    59281 tttgggtgct gtgacaaaag tcatgtcaca gctccttttt tccgaataaa cattgttctc
    59341 ctgccaactc ctcggtcaca agtcacaata tccaataaat ataagaagct gttttttgaa
    59401 cttgttcctt gtgactcgga gttaaacggc aggctcacga cctctttctt aaacggtgtt
    59461 caatcagctg ttcctcggta ttagctcaaa aaccggcaaa atataaggag atatttttcc
    59521 gtatgtttct ctaatactca ggtcaaaacg ctgatttcac aacctcttcc ttaaacggtg
    59581 ttcaaaagct tgcatctgcg gtaataagtc caaccaagtt aaaaacatta agaagctgtt
    59641 tttacttggc tgttcttatt acttgatgca gggcagcttt ttcacaacct cttggtacac
    59701 ggtgttccag aagtagcttc ttcggcaata agccgaaata tcacaaaaat ttgagaagca
    59761 attttcgtaa attccttctt atttcttgaa gctgaccact tctgtcacaa cctctttgat
    59821 tacttcgttt gattttattt taatataagt tgattaaaag agagcatgat ttgttttatt
    59881 ttctcactaa tttttccaac acaactaaga ataccataaa agctgatttt ggaggaggtt
    59941 cctactacaa gtctaaaacg aaatttaaga cttttcctca taaaatactg gtttattttg
    60001 gtctcatgta aaactcgctg aaggcctctt cacttataaa tgcttcccca gctgccagta
    60061 cgtctttcat ttggatcgaa tcgatgattt caggaagatc aaataaagtt cgatcgccaa
    60121 ataaactttg cgtaaattga ttggcaatat attcgatcga atttaatgat tggaaatatt
    60181 gtccaagcat tttcttcttc agcaaatcga gatttgtttc tgacacttcc ggatcatcag
    60241 cgaatccaag aatgatttct ttgacttttt ctgctgcttt ctctggttcg tccgtatctc
    60301 cgctgaagtc cgcaaagtga aattcacgat ccaagctgaa ttcaaaacca aagctgtcat
    60361 cgataattcc ttgattgtac atcgctagat agtttcgaga agtattgcct aaaatcattt
    60421 ggaacaacag attgattgct gttttatagc gtaacagttc tgttccttct tgcggcaatg
    60481 tgtctaatcc tttaatacca agtacaaatt tatctcgtgt aatggctgct tccaatgcac
    60541 tttgtttgat gatttctttt gtgttttcag ggaaataacg tacaatttct tgctttggag
    60601 ggaaattttt tgcttcttgg ttttcccgaa taagtttcat caatttctca ggctccatct
    60661 taccaactac aaataaaacc atattgcttg gctgataaaa cgtccgatag cacgtataca
    60721 agtcttgagc tgtgattttg tcgatacttt caaccgtgcc cgcaatatcg atatgcaatg
    60781 ggtgtgtagg atacaagtta tttagtatgc caaaaaacat ccgccagtta gggtcgtctt
    60841 catacatttg gatttcctga ccgatgattc ctttttcctt gtttacagtt tcttctgtga
    60901 agtaaggtgc ttgtacaaaa tcgatcagag tcgtcagatt cttttctacc tgatccgtcg
    60961 tagaaaacag atagctggtt ttcgtaaaac ttgtgaaagc attggcggaa gctccttgtt
    61021 tcccaaataa ttgaaagaca tcaccatctt ctttttcaaa caacttatgt tctaaaaaat
    61081 gggcaattcc atctggaact ttcacctttt ctttttcacc atagggaata aattcgttat
    61141 cgatcgaacc ataattcgta ctgaacaaac catatgtctt gtgatagtca tttttaggca
    61201 acaaatacac ggtcaaaccg tttggcagta cttcatgata aagtgtttca ttgatttgct
    61261 catattctgt tttattcatt tgcatttcct cctgctaaaa agaagattgc ctgcaattcg
    61321 atttgctcag ctacttgttg tatctctttg atcgttacgc tctccatacg tttcaaccat
    61381 tcttcatcag ataattttgt ttccggcagc cagctgtcca aaaaagaagc ttcgattgcc
    61441 gcttgcggag agtctagaga aagcagatat tggtttctca gcattgcttt tgtctgagac
    61501 agttccaact ctgttatttc accatttcgc aaactttcta attgctcgtg aatcagatga
    61561 agtacttgat ttcggttctt ttcatcgata ccggtttgga cactcatgaa tcctcggaac
    61621 gtatccacgc tactagaggc ataataagct agactttctt tctctctgac attcatgaaa
    61681 agtttagagt gaggaaaacc gccaaataaa ccgttaaaga ccattagcgc aaaacgttct
    61741 ggttcatcgt aatacacatt tgtctgataa gctaggttca gctttgcttg aacgattggc
    61801 tcacgtactt gtcgttcctt cacgatattc acttgaggtt gggtataaaa cagatctgga
    61861 taaactgttt cccgcgactc aaatggtaat tgcccaactg cttcagctgc tttgtccgga
    61921 tcaacatcgc cgacaacaaa aatgtcgatt tgatcatttg ccatcatttc ttgatagtag
    61981 gacgctagcg aactagcagt gatcttgtcc aaatcttcga ctacgcccaa ccctgggatc
    62041 ttttgttccg ggctgttttc aaaataaagt tcttgcaagg cataggaagc aaaagtttgt
    62101 ttatcttcct tcaaactttc caaatataga cgcagattgt tcttttccaa gtcaaacgtc
    62161 aactgatcaa actgatgatt tttaatattt ggataaaata aaacctcttt taaaaaatct
    62221 accgcttgag aaaaaaggtt tggatcattg acatattcac cattcacaaa actgatccct
    62281 gcgtttagcc aatgtaaatt tccttttttt ctaactgata atccaaagct tgcgccataa
    62341 agctctgcaa gttgcgcact taactttgtc tgatccgaat aattcaaact atttgtttcc
    62401 aacatgctgc tgagaagtga acgtttcgtg atgacttctt gttgcagacg cgcagtaaaa
    62461 cggataaaaa tccggatcgt tttgtattgt tttgttggta agacatgaag attcacgcct
    62521 tctgccaatt gatacaccat atttatatgc tccttttcac agttgattgc ccgcttactc
    62581 ttttaatggg tcaacctgcc ttttttactt attcctctgc ttgaaattta taagttcagg
    62641 caattcgccg ttttttctaa atgatgttac actttatagt atagcataga tgttttttat
    62701 caaaagaaac agacggctaa aagcgtatat tgttttttta ttttttattt ttcgatatac
    62761 taaagacaaa taaaagaagg gagggtcatt catgatcaaa gaattcaaag agttcatcat
    62821 gcgtggagat gtcttggatc ttgctgtcgg cgttgttatt ggtagtgcgt ttacaagcat
    62881 cgtaaaccaa gtggtgcaag gcttgatcac accactaata ggttggtttg tcgcaatgat
    62941 cacaggtact tctgatttag aaggagcact ttcaattctt gactggtcgc cgacaaaagg
    63001 cgtcacattt gcgtttggta acgttattag tgctatcatt acatttctga tcactggttt
    63061 tgtcttattc ttagttgtca aagcggcaaa ccgtgcgaag aatttacgct ccaaagaaga
    63121 gcaagtggaa gtggaagaaa ctcctactgc agaagattat cttagtgaca tacgcgatct
    63181 tcttgccaaa caagtggcag aagacaatac acatccagta gagcaaacaa atctttccga
    63241 tacttctaaa taataaagaa tctaaaaaaa agaaagccga ttttcagtgt cggctttctt
    63301 tttttagatt cttaacttgc tacttgttcc tttttcatgt cgatatgtgg aatatcatct
    63361 tccaaataca catctgagat tgccttgaat ccaaacgact cataaaaagc ttgtaggtat
    63421 tcttgtgcgc cgatcacgat tggtttttct ggaaaatttt tctggatcat gttaatcgtt
    63481 tcttgaacaa tctttcttcc taaaccatct ttacggttgt cctgatgaac aaggacacgt
    63541 ccaaaatgga tactctccgc ttcttcatat actcgcgtgt aggcaaggat cttcccatca
    63601 gtatcttgaa aaaacgtatg ccaagcttct ccatcaatgt catcaacttc ttgataagga
    63661 cactgttgtt ccacaacaaa aactgcgatt cgttctttga cgatcgcgta aaactctgct
    63721 gttgacaatt cttcaaattt ctttacctga tattccacta agcaaacgcc ccctgctttt
    63781 ttattcttag cataccgatt cgcacacaaa aaagcaaacg aaccttacga atctcaggct
    63841 cgtttgcttt ttaaactgct tcagttaaaa attcgatctc aactgtccga gtaagtacat
    63901 ctgaatagct gtaagatact cgttcaaaag aattttcttc aggatccaaa tcaacaacga
    63961 atactgaagg ataggtttct gttaaaacgc cgcggcgttc tgtttgacgc tttcttcctg
    64021 tctgagcaac caacatgatt gggctgccga tacgaccttc taaatctttc ttgattgaag
    64081 ctaaagttgt tggcatacag ttcacctcta ctatcaacta taccacatat ttttaaaatt
    64141 ttcaagttta ccataaaaaa aaaagaaatg caataaaaat aaataagaag ctcattaaga
    64201 tttttctaaa ttattcctca ttataaaatt tcaagtgttt ttttattttg agttttactc
    64261 tcccgtaagc gctcattact tgcttgtgat ccattgctaa acattcagcc atgtctacaa
    64321 aatcaacgcc ttgcatataa taatgaaaaa ttttagcttc tatttttgaa aactggattt
    64381 cgcaattttc gattgcttct tttaataaaa gatgctgaat tgctaaaggt tcttgcaatg
    64441 tgatctctgc taaaaagtct ggtccttctg tctctatttt ttggtcgatt gagacttcat
    64501 ctttttgatc acgacgcttc agcgcgttct gcttcctcaa cagagaatag atttgattgc
    64561 ttataacgct tttataataa cttccaaagc taacaccttt gcttttttcg taagttctca
    64621 atgcctgata taaagcgatc cttgcttctt gttcccaatc ctcagaaaca taatttctta
    64681 aataataggt gtttttcaaa cgtagtaaaa gtggaaaata tttttgatac agggcagcaa
    64741 atgcttcttc gtcaccatta cgtgcagcgc gcaataactc ctcagacata aaataattcc
    64801 tccataaatt cgtttatgga ggaatcttat catcaatgat tcatcgaact gattagaacg
    64861 atatgttatt tattttttct cattaaatcg tccaattttt gggacaattt ttttaactgc
    64921 tcttcattcc atggagaatt acgtcggaaa tcaataaaat gcatatcttt attttcttgg
    64981 gctattgttt tttccgtttt ttttatcgtc ttatataatt cataagcaga agttcgtaat
    65041 gctccttggg aaaagatcat ccactgttct gctaaatcgc ttgtcgccac tgtcacttgt
    65101 gtcaaacggt cattcagctg accagcgatt ctctcgatat aactgtcagc cgtttcgtct
    65161 tctttcgtaa aaacaacatc caactggtat ttcttataat tttgttggat gcccggaact
    65221 agttgggcat cgaagacaac gatgacttcc attccttcat atttcgcata atttgataaa
    65281 cgatgtaaaa gagcttctct tgcatccgcc attttgtcct gctttttaag ctggacaagt
    65341 tccggccacg aaccaatcat gttgtagccg tctacaatca acagctgttt tttcatggtc
    65401 tactccccct gacgttggga aaaagcctga tacataagca aaccagcagc aacactggca
    65461 tttaagctct ggacgtgccc ggtcatcggg atcgtcagca attcatccat ttcttttttc
    65521 aatcctggac tcattccttt gccttcatta ccaatgacta aagcaattga tcctttggca
    65581 ttccattttt ggaagtttgt gccggtcata tctgtgccaa atacccaaaa tcctgtttct
    65641 ttgagctgtt gcacagcttg taccaaattc gtcacgcgtg caacagggac atgttcgact
    65701 gccccagtgg aagtctttgt tacgataggt gtgattccaa ctgctcggtg ttttggtatg
    65761 atcacaccat cgacgccact tgcgtctgct gtccgtaaaa tcgacccaaa attgtgtgga
    65821 tcttcgatgc tatccaaaat caaaaagaag gggtcttctt ttttctcttt tgttcgttca
    65881 atcagttggt caagggataa atattcataa ggtgtaatcg caagaacgac tccttgatgc
    65941 acgccgtgat cgctcaaagt ttctaatttt tgtttaggaa cccatttgac tggcacagct
    66001 tgttcacgtg cgatttcttt cagttcttct actttttctc ctcgtgaatc ttcttgaaga
    66061 aagagtttat tccctcgccc ttgttgtagc gcttctactg cggcatggtg cccaaagacg
    66121 aaattatctt ctaatgcttc ttcattttga tcagaaactg actgatttcg tccagtttgc
    66181 tttttatttg aatatctatt ttgttttttg tcttcaaatc cacgtttcga ttgatgtttg
    66241 tttgttcttt ctttacccat ttttttcacc aactttctga atacaccagc ggatcaattc
    66301 ttccatccgc tcggtttgtt ttgtcaaatg cagatagccc atgagcgctt cgaaccctgt
    66361 tgcgacccga tacgtcgtaa catcagcatt ttttgcgctc gtatggcttt tagcatttct
    66421 tcctctgcga taataaagtt cttcttcttc tgtcaaaaga tgttcttcca gcatttgctg
    66481 aatcaaaaag gcttgtgcat tcgcagaaac ataattcgtt gccgcacgat gcagcttatt
    66541 gggttttgtt tctccttgat caatcaggtg gtcacgaaca tagatttcgt aaatcgcatc
    66601 tccaacataa gccaaggcta aaccgttcaa ttgtgtgtaa tctctcatgc ttctcttctc
    66661 catcgggttc cttgcggtgt atcttctaat aagatccctt tttctttcaa caaatcacga
    66721 atttcgtcgc ttcggacaaa atcacgattg cttcttgctt gatttcgttc ttcgatcaat
    66781 tgttcaatct cttcatctaa taactcttct gctgtaaata aaataccgaa gatcgaaagc
    66841 cattgcgaga ataaagcttc tccttgtgcc aagacagcgg cagaaacttt cggctggtct
    66901 agataagtgt tcagccactt agcaagctca tagaccactg tgatcccatt tgctgcatta
    66961 aaatcatcgt ccatttcttc gatgaatcgc tgttctaaat tttctaacaa agcgatttta
    67021 tccgcatcat ctgccaaatt ctctgaggca gtttcttggc ggaatttcaa attgtcaaac
    67081 gtattcttca gtcgttgtaa attggtggct gcttctttca tcgtcgtttc actgtagcgg
    67141 atcggacgac ggtattgtgt ggtcgccatg aagaaacgca agacttgtgg atcaacgttt
    67201 ttgatcattt catgtacagt gatgaaattc cctagagatt tactcatttt ttcatcgtct
    67261 tcgccaatcg ttacatagcc attgtgcatc cagtaattag cgaatttttt ccctgttttc
    67321 gcttcacttt gtgcgatttc attttcatga tgaggaaatt ctaaatcttg cccgccacca
    67381 tggatatcga tcgtttctcc taaatgtttt gttgccataa cggaacattc aatatgccaa
    67441 ccgggacgtc ctttgcccca tggtgaatcc caagaaatct cgccaggttt tgcttgtttc
    67501 cataaagcga aatctaatgg gtcttctttt tgctgctgtt cttcccctgt acgctgactt
    67561 gctccgactt ccagttcatc gatggattgg tcacttaatt tcccataatt ttcaaattta
    67621 cgggtacggt aatacacatc acctgaagat tcataagcat agcctttttc aaccaacact
    67681 tgaataaatg ctaaaatatc tggcatatga tccatgactc ttggatgcag tgtagcaggt
    67741 tcgacattca acgctttcgt atcttcttca aatgctcgga tgaaacgatc agcaacttct
    67801 ggtgctgtaa tacctaattc gtttgctgta cggatgattt tatcgtctac atccgtgaaa
    67861 ttcgatacga aatcgacttt atagcctcga tattcaaaat agcgtcgaat tgtatcgaaa
    67921 gcaatggtgc tacgagcatt tccgatatgg atataattat acacagtcgg tccgcagaca
    67981 tacataccga catgtccctt ttgtataggg atgaattctt ctttttttct ggtcaatgta
    68041 ttgtagattt ttatcattct gatctcctca ctttttctcc tttgattcga acgacttttg
    68101 ctggtactcc taccgctgta gcgtcgtctg gaacatcttt caacacaacg gcacctgcac
    68161 cgattttggc gttttttccg atcgttaccg gtcctaatat ctgcgcattc gcagagagca
    68221 tggctccttg tttaacagtt gggtgtcttt tacccgtttc ttttcctgtg ccgcctaatg
    68281 ttacgccatg gaataaaatc acatcgtcct cgatttctgc ggtttcgcca atgacgattc
    68341 ccattccatg gtcgatgaac acgccagttc caatcgttgc tcctggatgg atctcaacac
    68401 cagttaggaa acgccagaat tgagcattga tcttcgccaa taaaaagagc cggtgctgat
    68461 ataaaaaatg agagaaacga tgccaaaaca aggcatgaaa accagggtat gtcaaaacga
    68521 tctcagctgt cgaacgtgca gccggatcgt ttctctttgc tgcatcaatc gctcgggtaa
    68581 accaactcat gactttccac tcctttcgta agaattttat gtaggaaatc atcttcttat
    68641 aaagaaaaga agcgcctttt aaataagttt ccttatcaaa agacgctttc cgcgtggttc
    68701 cacttttctt cataatcaat gattatctct gacagctaac gcctgttata cgttcttggc
    68761 tactttgttt cctataaaac agtttttcct gttttctgtg tttcgccaag accactccca
    68821 gaggcatttc ggcaaccatt cattgatacc ttgcaccacc cggtatctct cttgtaatga
    68881 tcagctgctt acttttttct gttcatcgtg tttagttcag tacttgattt aaatgtgcta
    68941 atgatttttc acgaccaagc aattcgatcg tttcaggcaa ttctggacca tgcatttgtc
    69001 ctgatacagc tacacggatt ggcatgaaaa gattttttcc ttttacgcca gtttcttttt
    69061 gaacagcttt gatggcagct ttgacagttg gagcatctac tacttccatt tgttctagct
    69121 gtgctttgaa tgcgtggaga acagtaggaa ctgtttcacc agcaagtact tcttttgctg
    69181 cttcattcaa tacaggatgt tcattgaaaa atagcgtaga cagatcaacg atttctgcag
    69241 catagctcat ttgaggttga tacaggctaa cgatcttctt cacccattcg attgtctttt
    69301 catctgggtt ttctgctaca cgtccatcag cgattagata aggcagacac atgtcagtaa
    69361 atgcatctag atccattgct ttgatgtaat ggttgtttac ccattgcagt tttttcgcat
    69421 cgaaagctgc gggtgattta cttaggcgtt ttggatcgaa cattttgatc aattcttggt
    69481 gttcgaagat ttcgtcttcg cccacaggtg accagcccaa taatgcaata aagttgaaca
    69541 ttgcatctgg tagatagcct aattcgcgat attgttcgat aaattgcaag attgattcgt
    69601 cacgtttgct tagtttttta cctgtttcac tgttgatgat caatgtcata tgtccgaagg
    69661 ttggtggtgt ccagccaaat gcttcataga tcatcagttg ttttggtgta ttggcaatat
    69721 ggtcatctcc acgtaaaacg tgagtgattt tcatcaaatg atcatcgacc gcaacagcaa
    69781 aattataagt tggcatacca tcgcgttttt ggatgacaaa gtcgccaccg atattatcgg
    69841 attcgaacga aatagcgcct ttcaccatat ctgtaaatgc gtattctgta ttgcgaggca
    69901 cacggaaacg tacaacagat tctagacctt gtgcttcttt ttctgcttgt tcttcaggtg
    69961 tcaagttcgc acatgttcct gcgtaatgag gcatttctcc tcttgcgcgt tgtgcttccc
    70021 gttctgcttc taattcttct tctgtgcaat agcatttgta tgctcgattg ctagcaagca
    70081 gctgatcaat cagcggttga tagatttctt tacgttcaga ttgacggtaa gggccgtatt
    70141 ctccaggatt ttcaggagat tcatcccaat tcattcccaa ccaagcaagg ttttccaact
    70201 ggcttttttc gccatcttcg atattacgtt tttggtcagt atcctcaata cgaataataa
    70261 agtctccatc attgtggcgg gcaaacaaat aattgaataa tgcagttctt gcatttccaa
    70321 tatgcaggtg cccagttgga cttggtgcat agcgtacgcg tactttcgtc attttcttcc
    70381 tcttctttca aactagactt tgactaacag caaaaattcc gtcagttacg gcttctcaaa
    70441 tatcatttat ttaaagccac tcagcacaaa ttttaccttt tctaaggtaa atagtaaagc
    70501 caactggttg aatttcctta ccagttggct gaatttcttt tttattttga ttgtttagtc
    70561 tttttctctg tctctttttt attgtcgatt cctcgtcctg catgtgcagg tttagcaaag
    70621 atcatgcgtc cagcagctgt ttgaagggca cttgttacaa cgacttcgat acgttcattc
    70681 atgtaatgct gtccatcttc tacgacaacc atcgtgccgt catcaaggta ggctactcct
    70741 tgttggcgtt ctgtcccggc ttttactact agaacattca tcgtttcacc agggatgacg
    70801 actggtttta cggcatttgc caacgcattg atattaagaa caggtacatt ttggaattca
    70861 gagactttat tcaagttata gtcattggtt acaatgacac catctaaaag cttagccaat
    70921 ttgatcaatt tgctgtctac ttcactgata tcttcaaagt ctccatcgta catttcgaca
    70981 gatataccct cttctttttg caaggcattt aggatatcta atccgcgacg accacgcaca
    71041 cgtttcaaac tatcccctga gtccgcgatg tattgtagtt cgtaaagaac aaaattaggg
    71101 atcatcaagg ttccttctaa gaatccagtc tttgtaatat cataaatccg accgtcaatg
    71161 atcacgcttg tatccaagat tttatattta tggaaatttt ctcctgattt tcgttctaac
    71221 agttgactct caacttgact agctgtttct tgctcgattt ttttgcttcg tgaaccaaaa
    71281 actttcttcc attcttcgat tcgtgtcgtt cccattctca atcccagata gcctaagatg
    71341 atcatcagta aaatcggcaa tacactattg acgaatggaa tttccatatt gtaaagaggg
    71401 gtcgagatca caacacctaa agtcaatccg atgatcgcac cgatcgcacc gaagagaaga
    71461 taagtcaagc tgacctcact tagtttttgt tctacttgtt tgataatagc tgagatatgt
    71521 ttggccaaca gcaaagataa taaaaagaaa ataagtgcgc ctaacaggct gttggtaaat
    71581 gtattattca gccatccgtt tgactgttga ccgattgcct gccaagctga gggtaaaaat
    71641 gaaataccca agcttgcgcc gacaatgatc atcagcaaag taatgacacg tttttgcatc
    71701 gtttttcctc cgtttcgaca atcatttatt agttagcgga acacacgctt caacgtttca
    71761 gccaaagttg ctactccaac tatctcgatt ccttttggcg cttcccagtt acctaagttg
    71821 tttttaggta ggtatacttt tgtgaagccg agtttttgga cttctttgac tcgttgttca
    71881 atatgactga cacgtctgat ttctccagtc agtccaattt caccgatgaa acattccgtt
    71941 ggctgtgttc ctttttcttt atagcttgaa gcaatactga cagcgatagc taaatcaatc
    72001 gctggttcat ttaattttac cccacctgca gcttttaagt aagcatcttg attctgaaga
    72061 agcaacccag ctcttttttc cagcactgcc atgatcagag atacccgatt gaaatcaaga
    72121 cctgttgttg ttcgtttggc atttccgaac atagtaggtg tgactaatgc ttggatctct
    72181 accaaaattg gacgtgtccc ttccattgcc acaacgatag cagagccagt tgcaccgtct
    72241 aggcgttctt ctaagaaaat ctgtgaagga ttagcgactt cttccaatcc atgctcatgc
    72301 atttcaaaaa tcccaatctc attcgttgag ccaaatcggt tttttactgc tcgcaaaatc
    72361 cgaaaactat gatgttgttc accttcaaaa tataacaccg tatccaccat atgttctaac
    72421 attcttgggc cggcgatcga gccttctttg gtaacatgac cgacgataaa aatggctatc
    72481 ccatttgttt tagcggtttt gagtagttct gcagtggttt ctcttacttg gctgacactt
    72541 cctgccacac ttgtgatgtc tggctgcgtc atcgtttgga tggaatcaat gataacataa
    72601 tcaggggaga tatgttcgat ggcacgactg atttcgttca tatctgtttc agcgtataga
    72661 taaaattctg tgttgatact tccgaggcgt tccgcgcgta attttatctg ctctgcgctt
    72721 tcttcgccgg atacatataa gacttttccg cctatggctg ctaattgctg agaaacttgt
    72781 aacagcaaag tggatttccc gatacctgga tcgccaccaa tcaagaccat agaccctggc
    72841 accacacctc cgcctaacac acggttcagt tcttctaatt ttgttttgat ccgaggttct
    72901 tttttaggga cgacgtctgc gatttttgtt ggttttgctt tttctcctgt caaacttgtc
    72961 cgagttctgc ggtccgttgt atcttgttcg atttcttcga ccatcgtatt ccattttccg
    73021 caatttgggc agcgtcccaa gaacttaggc gacacatacc cgcaattttg gcaaacaaat
    73081 tgtacttttg atttttttgc cattgtaccg cctcctttta tcctaatcat gagacattaa
    73141 atcaagctta agtatcttta acgttttatt tactggaaga accaaatccg ccttgacgtt
    73201 gagcagtcgt ttgatcttga tctgctttta aaaacggcaa aaagatccct tggccgatac
    73261 gctcgccttt tttgatcact acatccttga aaccaaagtt ggtgaattgg aacatgatat
    73321 ggccttcatt tgcctcatta ttgtaataat cactgtcaat cacacctact ccgtttgtca
    73381 acactaaaaa ccgcttcaac ggattgcttg aacggttagc aagctgcaaa aattcatctt
    73441 ctcccatgta agctttgatt ccagtaggca cgagggttgg tttcaattgt ttttcatttt
    73501 ctgatacatc ttttttcaat ccatctgcga ctgtttccaa cccctttttc cagcctgctt
    73561 tccagatact tggaatcacg acctcttctg ctgcttcaaa atcatagcca gcagcatgat
    73621 gtgtagcgcg ctgcggtaga ttgatatttt gatctttata tttagaaata acttcaaatc
    73681 ctctttttct caccggtttt cctccctaaa taaactactc ctattctaac atatccgagg
    73741 ctgtaaaaga ctttctttac aaattcttca agaaattctg ctatcttaaa gtaaaccatt
    73801 aattcgttct ttttccaaac gactgcaagt tgtacaaaaa aactattttt tacatgactt
    73861 tactcgtcaa aacaagtaga atagaacgaa attaatgagt ggatatttga ttgaggtgtc
    73921 acatgcgtaa agaaattaaa aatgcaaaac gaattattgt caaagtagga acaagtacat
    73981 tgatttatcc caatggaaat atcaatcttg cggcaatcga tcagttagct tttgtccttt
    74041 ctgatcttag aaatcgggga aaggaagtga tcttagtctc atcaggagct gtaggcgttg
    74101 gtatgcataa attacatttg tcagaacgtc cgactttgat tcctgaacag caagctgcgg
    74161 cggctgttgg tcaagccgaa ctgatgaata tctataatca aagattcagt gtatataatc
    74221 aacagacggc acagatcctc gtgacaagag acgtggtaga ttatcctgaa agtcgtaaaa
    74281 atgtgaggaa tacattggaa cagcttttga ttatggacac gatccctatc gtgaacgaaa
    74341 acgatactgt agcagtggat gaattagatc atctgacaaa atttggcgat aatgatcagc
    74401 tgtcagccat catggcaaaa cttgtcgcgg cagacctttt gatcgtcctt tctgatatcg
    74461 acgggtttta ttcagataat ccgactacaa atcccgaggc tcagatgtat cgctatatcg
    74521 ataaaatcga tgaaaagatt ctggcacaag caggtggtgc tggtagcaca tttggaacag
    74581 gcggtatgca gagtaaatta aaagccgctt ctaggatatt tgaagcaaac agcgcaatga
    74641 ttttagcaaa tggaaaaaat ccggcaatta tttttgatat tcttgcagga aaagaagtag
    74701 gtactttatt taaggaggac ttgaaatgac tgacttgatg caattaggac aacaggcaaa
    74761 agatagcgcg caacaactag cacttatgcc tacaaaccgc aaaaatgagc tacttgttca
    74821 aatggcacaa accatcaaaa agaatcaaca agcgatcatt gaagcaaatc ataaagactt
    74881 agaaaaagca gtcgaaaaca atatcagtga aacgatgcaa gaccgcttgc agctgacacc
    74941 tgagcgaatc aatgccatgg ctacagagat cgaaaaaatt gcttcgttag acgatcctat
    75001 tggaaaagta gatgagatgt ggacgaacac cgacggattg agaatcggca aaaagcgcgt
    75061 gccactaggc gtgatcggca tcatttacga atctcgtcca aatgtcacga cagatgcagc
    75121 tagtctagca ttcaaatcag ggaatgccgt tatccttcgc ggtggcaaag aagcattctt
    75181 ctcgaatcaa ttattagtcc aattattgca gcaagtactg gtcagtgctg gcgaatctcc
    75241 ttatgccatc cagtttgtcg atgatacttc tcatgaaact gcaggacagt tgatgcgatt
    75301 gacagaatac ttagatgtgc tgattcctcg aggcggagca aaattaatcc aacgagtcaa
    75361 agaacaggca acggtaccta tcattgaaac aggtacagga aataatcacg tatatatcga
    75421 taaagaagca cagttatcta tggcagtgaa catcatcgtc aatgcaaaag cttcccgtcc
    75481 atctgtctgt aacgcggcag aaacattgct gatccattct gagatcgcac cttttttctt
    75541 gccagctatt gaaaaagaac tggtagaaca cggggtctct ttacgtgcgg atgctcgtgc
    75601 gttagaatat ctagagacgg ctgctttagc agaagacaca gattgggata ctgaatatct
    75661 agattatatc cttgctgtca aagtggtcga ttctttggat gaagcaattg cacatatcaa
    75721 tcggcataat actaaacatt cagaaacgat cgtgacagat agttatgcgg ctagtcaacg
    75781 tttcttaaat gaagtggacg cggcggctgt ctatgtcaat gcctccactc gttttacaga
    75841 cggatcggta tttggttttg gtgcagagat tggtatctct actcaaaagt tgcatgcccg
    75901 tggtccaatg gggttaaatg aattaacttc cacaaaatat atcatttatg gcgatggaca
    75961 aatccgcgaa taatgtttcg tgtgaaacat tattcccgcc ttttgccttt tttctgtaaa
    76021 ggttctatcc aactagaaag gtgtcaatat gtttgaaatt ttaatgattt tttttattta
    76081 ccttatttct ctgaatatcg ctgcttttct gggagtcggt attttatccc ttttctttca
    76141 attcaaaaaa cgaagcatag ggagtcaacg ggaaaaatgg tcgcagtatt ttgacaaaat
    76201 cgggcaaaaa gggctggtta cacgcttgca cattagttac atggttgcat tatgcttatt
    76261 agcgacaatc aattactatt cttttttcga tcattcaatc gcttatacga ttacgctact
    76321 gattgctggg atttttcact tatcttataa atatcagctg aataaaaacc acttgaatcg
    76381 gactttccgc taaaaaatat ccgtacgata agtagagtgc cttgaagatc ggcaaaaaac
    76441 tgccggactt tttagaggct gtgacaaaga ttttgtcaca gcctcttttt ccatataaac
    76501 ggcgttcgcc taccagctgc ctggtaaatc tgtttcctct tcgttaagaa gcgaaaatcc
    76561 gtcaaatgtt tcgccatcat aataacgaag cagctcatcc atggacaagt tcatcgtttt
    76621 ttctttttct tcttccgctg attcagccag tagctgttcc cgatacacct gatacatacc
    76681 agctattttt tgctgcatcg cttttctagt ttcaccttcc gcattgatta ttggcaattc
    76741 tttgatatag ccacgataaa tcaaccgatc atctgaaaat tcaatgggta attcaacgag
    76801 tgtcaacccg acttcctgaa aatattcttc cagcatctat tatcccccca ttctttttct
    76861 taaatgaatt ttagcttacc tactgaaaat tttccagttt cattattttg agaaaaaaag
    76921 ggaatgtgac aaaaatcgtg tcacatcccc tttttccgaa taaatggtgt tcttctgcca
    76981 actcctcaat cataagtcac aatattcaac aaacatgaga aactgttttt tgaaattgtt
    77041 ccttgtgatt cagagttaaa cgacagtctc acaacctctt ggtaaacggc gttcaatcag
    77101 ctgaccctcg gtattagctc aaaaaacggt aaaatatgag aagctatttt tccgttttgt
    77161 ttctctaata cttaggataa aacgctgatt ttacaacctc tgttaaacgg tgttcaatca
    77221 gctgtccttc ggtattagct caaaaaacgg caaaatatga ggaactattt ttccgtttgt
    77281 ttctctaata ctcaggacaa aacgctgatt ttacaacctc ctgataaacg gtgttcaaaa
    77341 gcttgcatct gcggtaataa gcccaaccaa acgaaaaata tgagaagcta tttttgtttg
    77401 gctgttctta tgacttgatg caggacagct ttttcacaac ctctgatttc ttattcttct
    77461 tcatttgtag caaaataatt acggtgataa atgatacaac atacactgat aagaacaatg
    77521 gcacctgcaa aataaaacgc atagctttca ccaatatgtt caccaatcac acctgcaata
    77581 aatggtgcta aagctccacc gaaaaagcgg acaaaactat agctggacga agcaacgttt
    77641 cgttgcagac ctggtatttc catagcaatc gtcgtcaaca gtgtattgat aattccttgg
    77701 aaaaatcctg ctaacacaat gctgatcggt acaaggactg gcatagaagt tccagctcct
    77761 aataacagca aacaaataat gaataagaca aatgctgcta aaattgtccg ataagtcgta
    77821 aacttccgct caagagccgg tgcaacgaaa atcgaagcaa tagccagaag cacaccccag
    77881 ccaaaaaata caaaaccgac ttctaattca gaatagccaa tcaataaaaa tggcgcatac
    77941 gcaagtaaag taaagaatcc gaaattatat aacaatgcga ttagtccaac tgaacgaagt
    78001 ttatgattgc ttaacgcttt gacaccttcc caaaggccta cttttctctt tggtttctca
    78061 gtttcaggta aaagtaccgc tagggctata aaaccgcaaa acatcaaaaa tgctacccca
    78121 aaaaatggat aacgccatga accactgccc aagaccccac cgactagagg gccaacagcc
    78181 attccgcagc caagtgctgc ttcatacatc atgattgctt tttctgtgtt accaactaaa
    78241 atactgacga tcgttgctaa agcagtagag acaaataaag cattcccgac accccagccg
    78301 gcacgtaacc caatcagcat tccgatattc ccagataatc cgccaagacc agcgaataca
    78361 acgatgataa acaatcctgt catcaatgtt tttttcaaac cgatccgact agataagaaa
    78421 cctgtaaata gcatcaccac accagtgact aacatgtaac tagtaaataa cagggtcgtt
    78481 tcagctggcg tagcgtttaa ctgtgcagca atcgttttta agattgggtc tactagaccc
    78541 actcccataa aagcgatcat acaggtagct gctacaacta gcgctgaact tttccccttt
    78601 gtttcttcat ttgtttgttc ttgtatatct atttgattct ccaatatttc catccctttc
    78661 tctctattag catcatacat gatttatttt acatgtcaat atgcacatgt aaaacgtgga
    78721 aactttactg tgatataata aagaaaataa gacgagaggt aggattttta tgaatacttt
    78781 agcctatata ttattatgcg tgcttttatc caaaccacgt tctgggtatg aattgaagca
    78841 gctgatcaca attttttggg aagcccatca cagtcagatc tatacaacgc ttgccaagtt
    78901 agaccagcag ggttatgtga ccgttttgga caaagacgag cactctcaaa aaaagatcta
    78961 ccacttgact gatgaaggac gtgctcttgt agaggaatgg atcaaagagg aaactcccgc
    79021 tcctacgcaa aaagatgaat ttctagcaaa aatctatgct ttttcgacgc tcgataaaac
    79081 aacagctact ggactgctat tcactagaga acaacagctg aacaaaatca tgcaaaaaaa
    79141 tcaaaaaaaa ttgaatgacc tctcgctaga caagaaacaa gaatttggac gttatgttgt
    79201 gatccagcgc agaattatgc tttgtcagca ggaactccaa tggtgtcagc aagtaagaga
    79261 acaaatgcag cagttttttg agtaagggat aaacagaacc tttctagaaa tatctattga
    79321 agagcaaatt atcttcaata aaagagcaat acagttggaa aagaaaaagc gatccgaacg
    79381 acaggccaaa acctatcgtt cggatcacta tttttctaga actgcattca agagactatg
    79441 acaaaaagca tgccaaggcc ttttttcaaa taacagtgtt ccatcattca ttactttgaa
    79501 ttgcttttag cacacttctt gaaagcgggc caacgatgat caactgcaac ggtaaagcgg
    79561 caatcacatt cattttccaa gcattcatat aagcagagaa taattgatca ggtattcctt
    79621 gttccatgat cacaccgaat aaagacatac atgtcaccat tcctaaaacc atcaagcatg
    79681 aaatagttaa gatcatttgg accttgcttt ctggatttac tggtagttta aaggcaattt
    79741 ttttcgccag cacaccgatg atgaagacat ccaaaatgaa agccaccacg aatccaggca
    79801 ctagaccaat caacaaactt gataaatgaa gatcttgatg cagccataaa ttatacgcgc
    79861 tcatccccaa gaccatcaaa aaacacatca ttgttgtaaa aattattcct tcttttttat
    79921 ttgtaggcaa tctgtaccac tcctttaaat ttgtcacgaa aatcatcgta gcacatttaa
    79981 aaatttctcg taagtacttt ttttattttc tgccctttta tttcataaac ttcatcagcc
    80041 gtacgctcga caaagtaaga atcatgagaa gtaaacaaaa tcgttcccgg atatatttgc
    80101 attagcttct ctaaagcttc gatcgttgcc atatcaataa aattagtcgg ttcatctaac
    80161 agcaacacat tacttggctt agtaaaaagc aaagcaatcg tcagacgggt cgcttctccc
    80221 ccacttaatg tacataacgg tttcgtcaaa gtttcctgag caaaccctaa gtgattcagc
    80281 aaactacgga caagcgattc tgaaaactct gtttgtctca tgacaaaacg aatgatggat
    80341 tcttcagatg tcatttgata acccttttgc tgatatactt gaaagcttac tttcggagag
    80401 agaaggattc cttctccttg tttgcggata tgttctaata aggttgtctt acctgaacca
    80461 ttttcaccga caatcgcgat ttttttacct aaagaaaact gaaaatcacc atttaccagt
    80521 aatgttctcc cacttctttc caattggaca ttttgtccca tgatgggata gcggctgtgg
    80581 agttcaagag attttggtac tggaaaacgg atttgtttca tctgctgcgg cttggttgtt
    80641 tctcctattt tttggagtct tctctctaat gttttcgcat tcttttggat ggctttttgt
    80701 acactgtctt tttgtttaga ggaagacaac cgatccagtc tgatttgttg ctttttcttt
    80761 ttactggaca ctttttccaa cttttccgct tgttttttct tttcttggat cgatttttcc
    80821 aatcgttttt tctctttcat gatcgactct gcttctcgta gctgagtctt tttctccaat
    80881 tccttttgag tgagataggc actataattc cccgaaaact ctcggatttc tccgtctttt
    80941 acttcccaga ttttcgatgc tagctcatct agaaaatagc gatcatgact aacaaaaacc
    81001 agcgtaccat aataataacg aagctcttca atcagtcgat caatactttt tctatctaga
    81061 tgggttgttg gctcgtctag aagcatccct tgttcataag aagaaagaag acgtatcaac
    81121 tcgatctttc gttcttcccc tccgctccat ttccgctctg aagtttcttc cagtcttaac
    81181 tggaaatgac tggctaattc caaatttagg tcctttgctt cagcgagata ggttaattga
    81241 ggcaggtagt tgaaggtgat ctctgtttgg attttcccat gatcgggaaa aagttcaccg
    81301 gctattagtt tgagcaaagt cgatttaccg acaccatttt ctcctatgat ccctatacga
    81361 tcttgctgat agacacgaag agaatcaata gatagttcta gctggttgcc aaagctgact
    81421 tgtagatttg ttatatttac tgctaaattt tccatatgtt ttacactcct atttcatgta
    81481 aaacaacaat tatcgatact aaaaaagagc agaaaaatct gtttgcaaaa aaactgcatc
    81541 acatcttttc ctactctgaa cgaaataact atgactaaat caccaaatct gtcatagctt
    81601 tcacctattc tactgtcgtt cgaaaaaatg gacatactcc atccatgaaa ttgttgttta
    81661 tacatgtctt ttgaatttat ttagttgtta ttcaaaagtt cgaaacgtaa tttcatcgat
    81721 gcagtcattt ttccgacctc cttttttatt aggttaccac acacgattca aaaaaagcaa
    81781 tagctactga atagtaactg aaaacctttt attcgaacat agtgatcttt tctggtgcta
    81841 aacgaacaga ctcgtaacct tcttctaccg cttttcctat tgataaaata ataactggaa
    81901 cataacggtc tttatccaaa ccaaatgcct ctgccaactg atctgcttcg aatccaccaa
    81961 ttggatttgt ttcatagcca tgatcacgcg caactaacat gaattgcata gccgctaagc
    82021 tagaatcgac tttgactaca tcgttcattt cttctcttga aaaactcttg taataaggaa
    82081 tgatcgcagc taattgttga tctctgactt cttttggcat cttccctgat tcgtaagctt
    82141 ggttgtagat ttcttcgcca tattcgtaac attgcatatc gccaaaaatc atgaccattg
    82201 cagaagaagt atcattttgt ctcgtattga aacggatcaa aggacgcaag atttcttttg
    82261 cttcctcgct ttcagcgacc acaaagcgcc atggtttcat attgacagaa gaaggtgcag
    82321 tcgtcgcttc tttgatcatt tccagcattt cttcgtgtgg gattttgtat gtttcatcat
    82381 atacgcgaac ggatcttcta ccagtcataa ttgttgaaaa atcatttttt tgttccatta
    82441 ttattaacct ctttcgtttc tgttgttata ttgcaaagtt gggtattcaa tttatctaaa
    82501 agtgttagaa attgtttcat ttctacatcg ctgaaagccg gggatagcac ggaacctgta
    82561 tctttatggt ccatttcaca atgcttgatt ttcttctggg ctttttctgt tagcgctaca
    82621 tacacttccc ggttgttctg aggatttctc tgacgcgaaa catagccatt tgcttccaat
    82681 accttcagat gacgagtaac tgctccttga tcaatctgca acttttcttg caaactgctt
    82741 tgtagcaatg gattttcttc tttcagtctc atcatgatct cgtatctagt aagacttata
    82801 ccgatatttt cttcaaagat ctggacgatt ttttgatcgg ctaatttgat ttgatataaa
    82861 aggtgactaa tctcttctaa agacataatt tcctcctttc taataattga ctcgtcaacg
    82921 attgacttgt caataataga ataaaaaaag aaaaaagtca aagaatcagc tgtgtaataa
    82981 aaaaaacgct ctcaatagaa aagtatagag aaaagaaatt ttttgtagaa tgaacggaaa
    83041 aaatgataaa gaaagcacaa cgctaaaacc aagattattg attcttatca aactatagaa
    83101 gatagctctt ctgcagtaga taattttaca ccgccaaaaa tttccgaaat cgccttttgc
    83161 aagaatcccg tcgaatatta gaaattggat cagtatgctt aaacagtaat aaaaaagtta
    83221 tgacaagatg ttgtcacaac cttttttgag taaacggtgt tcaaaaactt gcatctgcgg
    83281 taataagttc aaccaaacaa aaaacatgaa aatctgtttt tgtttggctg ttcttactac
    83341 ttgatgcagg gcagcttttt cactacctct ttttaataac cataaaatcc tattccttca
    83401 tatctccagc ccatcggtgt tagccaatct ctttccttag cactcaaggt atagtgatgg
    83461 gtaccagttt tttcatttgg attaaatagt cgataaattg gcttggaacc accagaataa
    83521 aaacttagac cttcataacg ccaaccgatt tttgttaaag agttgatctc agattgtgcc
    83581 attgtgtaat gatggtctcc actgtaagga ttgtataaac ggtagacagg ttgtccgctg
    83641 tttggtgctt gccaagcaat cccttcatat tcccagccta cagttggcag ataatttttt
    83701 tctccggcat tcaatgtata taaatgttct cctgtatgac ggttatacag acgatacatc
    83761 ggagaagttg aagttggtgc tgtatcatac tgtgtcagat tataggtttc gattacattg
    83821 ttcaatgtag aaccataatt aggcgcagtg gcataacgac ctgttagcca agccgtagca
    83881 tctttgtaag agttcgtatt gcttttccat gcaccggaat agtagtaaac gcctggctga
    83941 aaagaagtcg tcttcaatac cgttacgtta tcttgcaatg attctttgta cgaaggatat
    84001 tttctaaaag cggcattcac cgtaatccat tgcccattca catattccga agtaggcatc
    84061 gtaacagatt ggccattata gcttccttta atcccaaata gattgtaatt aggggcagaa
    84121 gccaaagtac tgttccccca gccactttca acgatggctt gagcaatcat gactgatgca
    84181 tataagtcat tggcacttgc caaactttgt gcagttgagg caatactatc aatgaacgct
    84241 tgttgagaat tagcagatga gcgagcataa aaagcatagc cagtatagtt ttcgaattca
    84301 gacaaatctg cttgatgggt atgtgtcaat gtttgcccat ctgtcaattg gttcgtgatt
    84361 tcttctgcat tctctggatt gttctgagct tctgctgatg tactgtcttc ggtttgtgtt
    84421 tgttctgttg tttcagttgt tggttcttcg gttgaaattg tattttctga gacagtagct
    84481 gactgcaaag tactttctgt atcgttttca attcctgttt ctgaagaact cgatgtctga
    84541 gttgcgacag tttctgtcga ttcttcagct agcactgttg tgttggcaac tgctagattt
    84601 cctaaaagaa taacgctaaa taataaattc tttgctttca tcttttttct cctttgaatt
    84661 atgaaacttt tcctaaataa cagtgtaact aaaaaagtaa aagcaagtca atgtccatat
    84721 ttaaataaca tttgtttctt tttaataaat ttgctttttc tgcataaaaa gacgtaaatg
    84781 aagaatattc ttctccattc acgccttaaa ttgatggtcg tttgaataac tatttaacaa
    84841 gtaattctct ctggatatta tccgttatgg attatacttc ctgtgtcgtc ggacggataa
    84901 tcatgttgct gacagacatc cggtctggcg tttctatcgc aaatgctaca gcagaagcta
    84961 tatcttcaga tgttaatccc cattcttttt gcgcttcatg aagttcaaga gcagcctttt
    85021 tgtcgctgat ggtttgatat aattcagttt gaacagctcc tggagagatg atcgtagatt
    85081 tgatgttatt ttgccgttgc tcttgacgta atccttccat gattgcacgg acagcaaatt
    85141 ttgttccgca ataaacggcg gaatcaggat aaacaacatg tcccgccaca gaatcagttg
    85201 aaatgatatg cccagatttt tgtttttcca tgattggaag tacggcggaa attccattta
    85261 acacacccat gatgttgata tcaagcatat tttgccattc atcacggtga ccttcaacta
    85321 atggagcggt tggcatgatt cctgcattat tgtacaatac atcgattcga ccgaactttt
    85381 ccatcgctaa atcgataact gcttggactt gtgcaaaatc tcttacatct gctgtttgaa
    85441 tatatagctc agcttctggt aaagattctt ttattgcttt taggcgatct tctcggcgtg
    85501 cagctataac tagtttagcc cctttttctg ctaatagctt cgttgttgct tcaccgattc
    85561 cgcttgaagc gcccatgatg acaatcactt tttctgataa atcattcatt ctattctcct
    85621 cctgttttga aaaatctctt gcttatactc actatctctt atttcatctt actgttcaaa
    85681 taatccgttc gacaggtttg acgattttgg cagggattcc tgcaacgatg gtattgtctg
    85741 ggacatcttt cgtaacagtt gcattcgctg caacaatggc attctcgcca atcgttacgc
    85801 ctggcagaat agttgctcct gctccgatcc aagcattttt cttgatgtgg attggcttta
    85861 ctgacaagcc tcttcgttct tttggatcgg ttagatggtt caccgtgatg aggttgacac
    85921 gaggaccaat caatactgaa tcttctaaac agatgccacc taagtcaacg aacatcactt
    85981 gacgattgat aaagacattt ttccctatac taatatgttt gccgaaatct gtataaaaag
    86041 gcagcagaac agtcaccgta tcatctactt tgtcactaat gatattttct agccgtttgc
    86101 ggatatctgc tggttcatgg tacccagtat tcagcgctgc taaaggctct tcgttttccg
    86161 cttggatctg atggatcact tcaaagagcg gatccgttac tcgaatctct ttattgacga
    86221 tttgtttttc gatgaggctt gtcattttgc tccctccttt tatccttact ttataacgga
    86281 cggcttatga tgtctaatac ttataaaaca tacttaacta ttccttttaa ctatacttag
    86341 tggtatgctt ttttaaaaac aggagggaaa aaatggatat tcgtatactg acgtattttt
    86401 tagcagtagc tagagaaaaa aatatcagcc gagcagcaaa atctctgcat atcacgcaac
    86461 ctactctctc aaaacaactg aaagatttag aagaagaact tggtgtgaca cttttcactc
    86521 gaggctcccg agagatacag ttgacggatt ctggtcgata tctttattca aaaggaaaag
    86581 aaatcttgtc gttggtagaa aaaacggcga acaatttaac aaatgacgca atcatctctg
    86641 gagaaatcta cattggcgga ggcgaaacta aagcaatctc tttcatttct gatagccttc
    86701 attcgttgat caaggcgcat cctgatatcc agtttcattt atatagcggg aatgcagatg
    86761 atatcataga caaactggat agcggattac ttgattttgg actcgtaatc gaaccgacaa
    86821 acaaacaaaa ataccagtca tttcgactgc cagcccaaga tcgttgggga cttttgatac
    86881 atcggaatca tcctttagca aagcaaacag tcatccatcc gcaggaactg aaaactgttc
    86941 ctttgatcat ttcccggcaa acgtcagtgg acagtcaact agctgaatgg ctaggtttca
    87001 gcatagatca gttatcgatc gtcggaacat ataacttatt gtacaatgct tctttgatgg
    87061 tcgataacgg gacttttggt gcattagctc tagatgggat catcaatact tatgggacgg
    87121 aaaaagtatt catcccactc gatccgccat tacaagcttc actgaatctc atttggaaaa
    87181 aagaccagcc tctttctcct gctgctcgta aatttttaga tgtcctaacg gagaaataca
    87241 gttaagtaga gtttttttcc ttcgctttca gctttttaac aacgaataag ttaagcaaaa
    87301 gatccaatga ttaaataaca taagtttctt aatttgttcc ttccttttat ttctgataat
    87361 tccagtaaat tactataatt ataaaaaaag aattgacaaa acataactgt ctatataaaa
    87421 ttgattacgt taacaataat tcgtttcatg tgactagatc atactaggca tgaaaaatct
    87481 ctgaggaaca tggtttccct aggaggtttt tcgtgtctat ttttgtttgg ccgcaatcaa
    87541 ctggtctagc aaacgtgaaa accaaatctt caaaaagggt gcgcgcatga aaatcaaaaa
    87601 gatctttaat caaaatgcag tattggtaga tgacggtgga caggaaaaag tagctattgg
    87661 aaaagggatt ggatttgaca gaaaaagaaa tgatttgatt tttgatcgtg atgtcgaacg
    87721 gatatttgtc atggaaccag aaggtcaaat caagttgcaa aatttactta atcagattga
    87781 tgaacgcttt ttatttgcag cagaaacgat cattgatcat gcggaaactg ttttgatgga
    87841 aaagttgaat gaacatgtat tgatcgcttt gaccgaccac attgcttttt ctgcggagaa
    87901 cattaataac ggtatcgtca tccgcaacaa acttttaaga gaaatcgaag tgctttacag
    87961 tgatgaattc agtattgctc aatgggcagt agagtatctg acaaaagagc ttgggattcc
    88021 atatacttat gacgaagcag gatatatcgc aatccatatt cacagcggac gaagcggtcg
    88081 gaacaataac catcgcagta tccgtgaagt gacgattgta tctgacatca tccatttagt
    88141 ggaatcagaa ttggaaacag atatccattc agaaccattt tcactgaatt attcaagact
    88201 ggtgaatcat ttacgactgc ttctacaacg aacccatgcg caacaatatg ctgttttaga
    88261 cacggaaatc gtagaaatgg tcaaacgaaa atacccagaa agctataaga tttctaaaaa
    88321 aatccgtgtg ttgctgacca aagaatacca gctcgcgatc acgaaagaag aactgggtta
    88381 cttggccatc catatcgagc gtttaagaag cgcaatcgta caaacaaatg ttaacaatca
    88441 tgaggaggaa aaaaattgaa agcatatcta caacgaatgg gacgttccct tcaacttcca
    88501 gttgcggtct tacctgctgc tgctttacta gtagggatcg gaaactggtg ggcatcttat
    88561 agtaacgaca ttgtcgctca ttttttacaa gctggcggta acgcagtttt aggtcaatta
    88621 cctttgctgt ttgccgttgg gttagcacta gggatgtcag tggacaaatc aggtgctgct
    88681 gccttggcag gtttggtcgc atttgaagtt ccagtaaatg ttttaaaaac tgattcagta
    88741 gctactttat tgaatatcaa accagaatca gttgatccat cttttgctca gatcagtaac
    88801 gtatttattg gtattattgc cggattgatt gcggcagctc tttataatcg tttccacgaa
    88861 gcaaaattac cgatggcttt atctttcttt agcggcaagc gtctagtgcc aatcttggct
    88921 gcctttgtca tgttgctgat cagtgcagtg ctactgctcg tatggcctcc ggtttactct
    88981 gctttagttt cttttgctaa attcattttg agtttaggct ggggtggtgc aggtctttat
    89041 ggcttcttca accgtttact gatccctaca ggattgcatc aagcaatgaa ctccgtgttc
    89101 tggtttgacg tagcaggaat caatgatatt ggtaaatttt tggcttctga aggaacaaaa
    89161 ggcgtaacag gaatgtatca agctggattt ttcccaatca tgatgttcgg gcttccagca
    89221 ggagcatatg ctatttacag aaatgcacgt ccagaaaaca aagcaaaaac agcttccttg
    89281 atgttagcag cagcttttgc ttcattcttt actggtgtaa cagaaccact tgaattctca
    89341 tttatgttcg ttgcttggcc attatatgtc ttgcatgcaa ttttcactgg gatttcttta
    89401 gcagtgagtg cattcttcca ttggacagca ggatttgcct ttagtgccgg atttgtcgat
    89461 tacttcctat ctttgaaaaa tccgattgcg aatcagccat tgatgttgat cgtccaagga
    89521 ttagtaacag cagtgattta ctactttggc tttaactttg ctatcaaaaa attccatctg
    89581 atgactcctg gccgcgagga agcagatctt tcagatgacg atactgcaac gactaattca
    89641 gacaataaat atgcggcaca agcaagcaaa atctacgctg cattaggcgg agccgacaat
    89701 gtaacttcga tcgataactg tactacacgc cttcgtttgc aagtcaaaga tacaggcctg
    89761 atcgatcaaa ataaaatcaa agccactggc gtacctggta tgaagatcat cgacggaaaa
    89821 aatgcgcaag tcatcgtagg tacagaagta caattcgttg cagatgagat ggcaaaacta
    89881 catggtggtg ctgcaacacg acctgcacaa acaaacaccg tggttaaaac agaaacattt
    89941 gccggtggaa cgatcgaaca agatatttac gctatcgcaa atgggaaact gattccaatc
    90001 actgaagttt cagatgatgt attcgcggaa aaaatgatgg gtgacggcta tgctgtatta
    90061 ccagaaaatg gagaaatctt ctctccaatc gctggtacga tcacaaacat tttcccaacg
    90121 aaacatgctg tcggaatcca aacagatgct ggtatcgaag tcttgcttca tatgggcatc
    90181 aacactgttg acttaaaagg cgaaccattc actttatatg taaaagaagg tcaaaaagtc
    90241 gcaagaggtc aattgattgc tttagttgat cttgccgcta ttcaatctgc aggcaaaaac
    90301 acggatatgg tcgttgtatt cacaaatggc gacaaagtcc aaagcttaga aatcgaaccc
    90361 gcacgtgatg taaaagcaaa tgataaaatc ggctctgttt ccaacaaagc ctgagccatc
    90421 gtcttcccca gactttttta tcgataaaca aacaggagct gagacaaaaa tcttgtctca
    90481 gctccttttt ccgaataaaa acggcgttct cctgccaact ccgcggtaat aagtccagcc
    90541 aaacgtaaca tatgaagagc tattttttat ttgactcttc ttattacttg atgcagaaca
    90601 gcttttttac aacctctgat aaacggtgtt caaaaaccag tttatcggta tgaagtcaaa
    90661 tttatgcaaa aatgtggaaa gccattttca caaaattttt cttcatactc aaaactaatc
    90721 ggctttttca caacctcttt atacattatt cctgatccaa tatttctttt aatgctgctt
    90781 caagagaagt taatggtttt cccaatactt tttctaaatc atcagaggaa atagctaact
    90841 gatccttttt aatatcatgt tggatcgcta aaaacatgtc agctgcttct tgagggaatc
    90901 cggcttcttt tagattttcg acaaacgctg catcacttgc ttcaataatt tctaactttt
    90961 tacctgtcgc acgctctaat gccttggcta attcttcata gtcagttaga ttgccggata
    91021 attctaagat ttctggagag tcactttcta ctagtacttt tgctgcagct tctgcatatt
    91081 cacgtttcaa tacccaacct gtttttccat ttcctgcagc ataaacgaat tgaccagttt
    91141 ttaaagcctg cccaatgata ggtaattcat tctctacata ccaattattc cgtaaaaatg
    91201 tatgggaaat acctgaatcc ttaatcattt tttcagtgaa ttggtgatct ggcgctaata
    91261 cactgatcga gtgatcggca tctgcaaaac ttgtataagc gatataagat accccagctg
    91321 cttgtgctgc cttcactaca ttcttatgtt cggcttgacg atttcctgga acgccagaga
    91381 caaaaagcaa tcgatctatt cctttcaacg cttctttcat tgagtctaaa tcatcataat
    91441 caccaatacg tatattaaat ccagcttctt tcagtgcttc tcctttttct tcactacgta
    91501 ctagtacata gatttcattt tgtggaacca tcttttttaa gaattccagc gcataaccac
    91561 caaaacctcc agttgctcct gttactaaat aatgcatatt tgccactccc tattcttttt
    91621 atttgttaag atttacagct gtacatttat aaattacacc tttatcataa agagtgtggt
    91681 aagataagtc aagcaaaaaa aatgaaagga tgacaactga tgaagtattc tctgcaattt
    91741 agtgatgcaa tccatgtact tgcctatatt gaaatgtttc aagatacccg atcactttct
    91801 agtgagatga ttgccagtag tatcgaaaca aatgcagcaa atgtacgtaa aatcatgagt
    91861 cagctcaaaa aatccggttt gatctttaca aaaaccggaa aaccgcagcc ttcccttgcc
    91921 aaaagtccag atcagatttc tttactagat gtctatcgca gcatcgaagg taatacacag
    91981 cttatccaag tcgatccaaa aacaaatcca aattgcgtcg ttggtgcgaa tatccaagaa
    92041 gctttagaag aaagctacgc tcggctgcag aaaaaggcag aagaagaaat ggctaagatc
    92101 acacttgata gtctgataca taaaatagcc gttttggaaa aagaaaaaag accagaaaac
    92161 acaggcctcg tagagagatt tttataattc tctctactgt gcctgcattt ttctgatcgg
    92221 aatcgtctac ataaattctt ttattctccg ggggacaaaa gccttgtcat gccccttttt
    92281 cctctctaat gctcaggtca aagcgctgaa gtcatgacgt cttgataaac ggtgttcaag
    92341 tagctgaccc tcggcattag ttctgaaaaa tgcaaaatat ggaaagctat ttcccatttt
    92401 tcctctctaa tgctcaggtc aaagcgctac tttcacgacc tctatattat catggtttat
    92461 tgactaccgg tatccagatt tctcccatat atttcccgtt ggtaactccc atttcgacta
    92521 cagcatttgg acccccaaca taggcgtaat cttctacttc tcttaaaaca tgcccaaagg
    92581 ccgtattcgt caaatcattt cttaattctt caggcgattc tgctaaagcg attacaacaa
    92641 gatacgttcc ttttgggaat gggatgattc gggtagtgtt tggaacatcc tgactcgttt
    92701 gaacaccgac atagtacatc attttcccgt tatagggttc gttgactgta aagaaataat
    92761 gattttcagc agcttgtttc aatgcatcta ttgttccatt accgataact ttttgctcaa
    92821 atgcttgttt ctctgcagcc aaaccgacaa aatccgtatt gctactcttc aattccacac
    92881 caatacccgt caccgtaaaa tctggttttt cttcgatcct atactttgcc atttctccca
    92941 ccctttctat tatattaagt tcatcttaca taaaattaaa gggaaatgac acgattacgc
    93001 tcttttttct agggatattt ttatttttta actatttttt tgctttcact gcaatccaaa
    93061 tctcactgta aacattactg aaatcctctc cccattttgt aaaagagatc tcgggagctt
    93121 cgactaactc ataatctgaa gaaggaagcc attctgcata gattttcccc caagtatctt
    93181 gtaaagtttg gggaaatggc cctttattag gaaaaatggc ccaagtgtgt tcttctatag
    93241 caagcatttc taaatcagcg tacggatttt cttttgtcgt agcaaagcca atcatgtgca
    93301 tcaaactgcc cttttcttcc aagcgggctc catcaaatcc ataagaaacg ttgattactt
    93361 gatttggata taaatctcct aacttatgca tctcttccct ttgagtctcc gtgatcgtct
    93421 gcgctaactt ttgtatttct tgattgactc cttcaaattt gacaggaact tttttcgcca
    93481 cacctgccac ataaaactgt tctttctttt cgatacgaaa ttccatcgat tttcctcctc
    93541 tgacatcaat aaaaaatgtc aagcgtggaa aagatttttg tatgccgtat ctgctgattt
    93601 ctgaaggcag atatcctgac caatcacgaa aagctcttga aaaaccttcg actgtttcat
    93661 atccatatct aaacgccgtt tctgtcactc ttgatccatc taggagatcg cgattagcca
    93721 aagccaatct acggtttttg atatagtcca ttagcgacat ccctgcaata aacgtaaaga
    93781 tgcgttttaa ttgatattca gagattcctg tattttcggc tattatttta taggaaagtc
    93841 cttctgtcaa atgttcttcg atgtaatcga tcaattggtt cagatcttta agcatattta
    93901 tcttcctcct tgcttgcctt tttatcatat tatcaaagaa agtcaattac ttgatgaatc
    93961 aggaaccaat ttagtcagat gtagaaaatg ttgtatggat ctaaagaaaa ttctcaagca
    94021 gcgtttcgta acggataatt ggtattatct gcctatctat gttttacctt tagaaaaata
    94081 aattttgggg aagacacatt ctaagtaaac aaagcggtaa aaatatcttt tattccctta
    94141 gttaatccgc ttactaccta ctgtacaaag caaattgttg ttcaaactgc tgatcagaac
    94201 gctgcttgga tttttctttg cgatacatca tacctctttt atcaattgga acaattattt
    94261 atttctaaca aaatcacttc atttttgtca gataaataaa aaacaaaaaa agttccatct
    94321 ttaaaacacg ctattctttt actttttctc acattctcta agaaaagaaa aggagaatga
    94381 atttttgaca attcgagcaa aagtgattat caaatatgta aaatcagcta cttttttctt
    94441 aaacgtttct ttatactaaa tataaataag tgtttcatga aaggagaact agatgaataa
    94501 ttggcttgag tattttcctg aaaacgtttt ggaacgcggt tacagctatc atctgcacgg
    94561 ttttgtccgt catttgaact atacaagcaa gtacttgtcc gcaacagttt ctggcacgga
    94621 agattataag gtagtgatca cttgggatga aaagaccaac atgacttgtg attgtctata
    94681 tgccatagaa ggaaaaaaat gcaaacacat ggctgctgtc ttattcgctt acgaagaacg
    94741 tccaataaaa aaatccaact actcactttc cgaactctcg tcccttgttt cctccgctag
    94801 ttcctctctt gtacgggagc ttttaacaga gattcttata gaacatccgc aatttatcga
    94861 acgcttcaaa gttaagatgc catttcatgc aataaattat tcagataaat taacaactat
    94921 catccataaa tacgatcata ttatcaagaa aaacaaaaac aggaaaacag cgaagttcat
    94981 catggagatg cgaaagttca tccaagaagc agttgaatcg ctcattcagc aaaatgccta
    95041 tcttcccgca ttcgaattga tcaatgaagt gattgctact ctcgaaacat tctattggga
    95101 gcctgaggat gaacgaaccc ttcttctgat agaggactgt tattatttat ggaaagaatt
    95161 attagcagaa gcacctcatg cagaaaaaag gcaaatgttc tcttggttcg tctgccaagt
    95221 cgatcatact gacgcctctt attcaaaacg ctactccata aaaatcctga aagaagactt
    95281 tcgggaaaaa gaattttcta accaaaagaa aaaaatagat aaaaaaacta aagaaacggt
    95341 aaagaaagac gatttcaatg aaaaatagca agtaaacgat aacaaccatc ctaaatccac
    95401 aagaaataca gcagaccttg ctttaaaaac acgaatcatg caaaggatga agtaaagaag
    95461 acttaacgcg tacccaatat tagtcatttg actattaggt acgcgttttg ttttataagt
    95521 catgacaaat ttccttcgtt gctgggtaga ttttccggca ttgttgatag attttatgat
    95581 acttttctac attttgtaag agaggttcca ctgcatctgt atattggata aaattctgac
    95641 aacaactttc aggtgtgtcg aaccactcta atctttaaag ataaatatta aaataacgat
    95701 taataatatt aacagtcttt atttttcacc accaaaaacc tatctttgca tatactaaat
    95761 agacgtatat acacagatag gtttgtcttg tgaaaaataa tgattatcct taccaaaaaa
    95821 tgtttgtttt tctacatgtt cgtacttatc aaaaaatatg atccttattg aaattactgg
    95881 ctatttatat tccaacgact tcttgtgtta atttttgtta tctcatagta aattatgttt
    95941 cattttcact taatttagtt gtcacgtgtt cgtcaattcg taaaaacggt aaatatataa
    96001 acacacttgc ggctataatt aatatttgta aaacagctgc tcgccagtct ccggctgttg
    96061 ctaaaaatcc cgatataact ggtggcgtag tccaaggaat ttgcactact acatgattaa
    96121 ttaatcccac agcagttgca aaatatgcta ctgtcaaaga aaaaatcggt gcaagcacaa
    96181 agggaataat cagactgata ttaaatacaa taggcaatcc aaaaataata ggttcgctta
    96241 tattgaatat agcgggagtt accgataatt tagcaaagtc cttataatct tttctacgac
    96301 tgaagataaa tattgcaatc aataaagcaa tcgtatttcc cgatccaccc attaccgcaa
    96361 aggtatcttt aaaggccata ttgataatat gtggaatttg ctctttgttt gcataagctg
    96421 ccatattttc ttgcatattc tgaatcaaaa acggatctaa caatgaacct gatattactg
    96481 cttgatggat accaaatcca aaaaatagat tagcaataga tgtaattaac aaaaatcctg
    96541 gtaaaccagt tgtaatttta cttaatggct ctgtaactat cgtggtaatt agcttattta
    96601 tatccatatt aaacaattga atgattataa atgacaataa agcaaacgag gtaatcgtaa
    96661 taatgattgg gattaataca ttaaaagact ttaaaacagc gggaggaata tttccggata
    96721 gctgaatctg tagtttctta ttattagaaa gtttaataaa taattctgta gccgctaatc
    96781 caacaaatat acctacaaac attcctgaag ctcctgtata ggatataggt atcacacccg
    96841 tcacttcaac agctttatcc gcattttcag gagtaaacat catctgcata ggtgttaata
    96901 caacaaatgt cgaaatagca actaataccg ctgcaatatg atttgtataa tttctgcttg
    96961 cacacatatg ataagatact gctgctacaa ctaataatgt agttatgctt aatgtaccat
    97021 tggcaattga agtaccaatt tgttgtaacg tggtcaatgt actagtatcg acaatttccc
    97081 ccatgaatcc tgttggttct aagatcactg aattaataag tgtcacaaat cctgctaaca
    97141 tcataaatgg cataaatgta gcaaacgcat ctcgcaaagt tcttaaatgg atctgattcc
    97201 ccaacttagt cgcaactata ccaaattttt caaatacaat gtccttcctg ctacttttgc
    97261 ccatattttt tctcctttat gcttattgta atcgattact ttttccaccc aaataataca
    97321 tcacttatca aaaaaagtaa atacttttaa ttaaatatat atatcttttt tagtataaaa
    97381 aaataagctc tgaaaaaata attttcccga gcttattttt caacaaaaac agcttcaaaa
    97441 acaaagtctt gatataaatg tctcgatacc gaatactcga aaggtttacc agacgataga
    97501 gcaacaactt tgtctatctc aatcataaat tcacctggat ctatttttaa tatttttgcg
    97561 tcaaattcat tcgcagtatc tcctttgata cgtatgtgcg aagtctttat ttccagaccc
    97621 agttcatttg tgatataagc atatacagat ttctttaaat gttttggttc caagcctggt
    97681 atgactgcta atggcatgaa tgtttgctca atcgagtatg gttgacaatc aataaaacgg
    97741 cttcgtacaa tattatatac atagtctttt acactgatac ttaatttatc agctactttt
    97801 ttcgatggaa gttcaattga gaaagtatgg atttctgaat ctacgtgttc ttcaccaacc
    97861 acgctaaaca aaccttcgtt tggaccaaga actcgtgagt tatcaattgg tgttctgacg
    97921 acttcagtcc catacccact tctacttcgc aaaactcctt cggaaacaag taagtctacg
    97981 cctttcttta ctgttaactt gcttgtatga taaataactg ccaattcatc tcctgtagga
    98041 agtttctcac caattttata ctctccattt acaatttttt tctttatatc taagtaaatt
    98101 tccatatact tcgcaatttt tttcaatggt gaccctccaa tcaaaaacat atcttcatct
    98161 atactttaac ataaataaac cgataaaatc cacatcaaaa ttatacacac aataaaaaag
    98221 atatatatat ttaaacaaaa ctatttactt taagttgtaa gcggtgttat cattaagtgg
    98281 aaacaggagg taaaaaaatt atgacaacta tgaaaaagct aacttttcca gatgattttt
    98341 ggtggggttc cgcttggtca gctgagcaag cagaaggaaa aggagaaaca ggaaaagcag
    98401 agactatctg ggatcgctgg tttaaagaac aaccttaccg gttttatcaa cgaatcgatt
    98461 cctctattac aaccgatcac atccatcaat ataaagaaga tatagaacta atgaaaaaaa
    98521 ctgggcataa ctcctttcgc gtttctattt cttgggcacg aatgtttcca aatggcggta
    98581 ccggaaaagt aaatcccaaa gccatttctt tctatcgaaa attattttcc gaaatgaata
    98641 ataacggaat caaagtattt gccaacttat atcattttga catgcctgct actcttcaag
    98701 ataaaggagg atgggaatca cgtgaagtag ttgatgctta tgttcattac gctgaaactt
    98761 gttttaaaga atttggtgac ttagtttgtc attggtttac cttcaatgaa ccacttgggc
    98821 ctattttagg tacttatctt gaagattttc attatccaaa cctcattgac tttaaacgcg
    98881 gagcgcaagc agcattcttc actatacttg cacacgcaaa agcaatacaa gtatttaaag
    98941 aactagctct tcctagtaaa ataggcgtta ttctaaattt gagtcctact tttcctcgta
    99001 gtcaaaatcc tgctgatgtg aaagcagcag aaatcgctga tttattttat acgcggagct
    99061 ttttagatcc tatggttaaa gggaattttt ctaaaaagct tatcctgtta ttacaagaat
    99121 ataatcagct tcctgaagat tatacgaaag aagatcttgt atgtatctac gaaaataccg
    99181 ctcaaattct tggactaaac tattacgagc cacgtcgcgt caaatctcgt tcttctatgg
    99241 tggatacatc tagtccattt ttaccagagt ggtttttcga accacatatc atgcctggac
    99301 gacgaatgaa cgaataccgg ggatgggaaa tttacgaaaa aggaatttat gatttgtgca
    99361 tggatatcaa gaaccattat ggaaacatcg aagcatttat ctcggagaac ggaatgggcg
    99421 ttgcggatga agaacgtttc atggatgata cagggcaaat aattgatgat tatcggattg
    99481 agtatatcaa agatcatctt gcttacttat ggaaggcaat aaatgaagga tgtaacatta
    99541 aggggtatca tctttggaca tttattgatt gctggtcatg gatcaacgcc tataaaaacc
    99601 gatatgggct ggtttcactc gaccttacta ctcaaaaaag aacaattaaa aaaagtggcg
    99661 aattttacaa gcaattaagt gatacaaatg gatttagata cgatgtagac ttgttagttg
    99721 aataatattc taaaattcca cttgaagtga acacattaga aaacaagaat aatgagaaat
    99781 accaataaca aatacttttt cttcatactt catttatact tgtcagtata agagactgtg
    99841 acaaatgtag tgatcctcag aagttaggtc tggaaatcta acttgagaag atttttttaa
    99901 actacgtcca gtctttttta tttgtttaaa attgaagttg acaagtcttc attaaaaatt
    99961 tagaatattc acaagtttga cgacaattat gaaaatttat gtcgtgctaa aggagttttg
   100021 ttattggatg aaaagttaga tataaaaact gcgatcaaag acacgttacc taccgttttt
   100081 ggttatatcg gtattggact tgcatttggt atcgttggga aagctgccgg gtttcatccg
   100141 ctggtcgtca cgttgatgtc cctgctgatc tatgctggtt ctgcccaatt tatcacggtc
   100201 agcatgcttg ctagccatag tccactgctc tccatcgttc tctcgacctt tctagtcaat
   100261 tcccgaatga ttctgatgag tatgacgatt gctccttatt tcaagaaaaa tcggctgctt
   100321 caaaatctgc tgattggcac attgctgaca gatgaaagtt tcgcactggg aatgaataaa
   100381 ttgaactata ctggacaaaa gttaaacttt cgttggatga atacagctaa ttggatttct
   100441 tatttgacgt gggtgggttc ttctcttgtt ggcgcacttt tagggaattt tattactgat
   100501 ccgaaaaagt ttggtttgga tttcgccatc gtcgctatgt ttatcgggtt actttatctt
   100561 caagtcattt ctgatagaaa cacctctaaa cgattacagt tgatcctgat tggtctcact
   100621 ttgattctgg tatatgtcgg actgattttt atcccaagta acttagtgat tttagttgta
   100681 acactgattg ggtgcggatt gggggtgtgg atcaaacatg ccttcttttg agtttacatt
   100741 gctgactatt ttaggttgta ctttagcaac ttggctttct aggatcctac catttgtctt
   100801 actgaaaaaa ttcgatttgc cgcaaccgtt gcttgagtat ttaagttttg tcccgatcgt
   100861 cattatgtct gctttatggt tcagcagtct atttacccaa aatatcggac atctgccgca
   100921 gatcaatctc gaaaatgctt tggcttcagt tcctacactt ttagctgcta ttctttcaaa
   100981 aagcttattg gtgatcgtct tggtaggaat tctttccctt tcgttgattc gcttattata
   101041 aataaaaaaa caagagctta tggcaaatta ctgtcatgcg ctcttgtttt tatcaaagtc
   101101 aaataagaaa aaaatcggcg tattcttgct tatccgttga acggaccact aacaacgact
   101161 tttcctaata tatgtcctgt ttctacgtct ttggttgctt gtttcaagtt cttcgcattc
   101221 atcccatctg aatagacctt gctcaatgta ctgcggataa tcccttcatt tgctaaagca
   101281 gcaatgtgcg ctaaagcttc tccttgcgtt tcgatttcat agttatagtc tgttttagcg
   101341 aacatatact cccagtcgaa gctgatagat tggtttttcc aaacacctat atctaacggc
   101401 tctttgatcc ctacgatcgt tcccacatgt ccaaatggtc ggacaaggtg tttgatttga
   101461 tcaaagtagc gggtaatatc gaataataca gcgacatact ctacttgatc gattcctaat
   101521 tcacgaaaac ttttacttaa gtcgtgatga taatcgattg gatagtctac acctgttttt
   101581 ttcagccatt caaaattctt cggacttgca gtcgcgtaga cttctaggcc agcccaatgc
   101641 gctagttgat tcaaaatcga accgacgccc ccagctccgt tgatcactaa gatttttttc
   101701 ccgcggttgg cattttcttc tggagtcaga ccaaattttt caaataacaa ttcataagcg
   101761 gtcaatgagg tcaacggcaa ggctgcggct tcttcatctg aaagattttt tggtgcaaga
   101821 gcgacaatac gttcgtcaac cagttggtat tcttgattgc ttcctgctct tgtcgttgta
   101881 cctgcgtaaa aaacgcgatc gccgacagaa aatttttgca cttcatcacc tacagcaaca
   101941 actttcccga ctccatcaaa ccctaagata cgtaaagcat ttcttatccc gttatcttgg
   102001 cgaagtttcg tatcgacagg attaacagat actgcgttga cttttaccag aagatcccgt
   102061 gaactgggta caggtatctg ttctttttca tcaataaagc tttttggatc atcgatcgac
   102121 aacccttcat aaaaaccgac taccttcatt aattcctttt ctgacatacg aattcctcct
   102181 tagcttcatc aagttggagc atccatacag ttttcatttc aatatatata gtatgctatt
   102241 tgttccactt ttattcatca taattattct cttacttaaa gtaaactatt tgcacttttt
   102301 tggttaaaaa agaggttgcg acaagacttt tgtcacaacc tcttttaaac ggtgttcaat
   102361 caactgaccc tcggtattcg ctcaaaaaac gacaaaatat gaggagctat ttttgtttgg
   102421 ctgttcttat tacttgatgc aggacagctt tttcacgacc tctaattcac ggtgttcaag
   102481 caagaaatca ttgttcactg aaaagcgttg gatgttcttt ttcaaaggtg tctaagatct
   102541 ctcgtacttc atcagtagat ttcgtattca tcaactgaac tcgcaagtca tttgctcctg
   102601 gaaatccttt gatatagatt ttaaagaaac gatgtagtcc tgtgatggaa cgcgggatga
   102661 tttctgaata atgatcttgc agatctagtt gcagacgaag tagtccgatc agttcttttt
   102721 ctgtatgttc cctcggttct ttttcaaatg cataaggatt cttgaaaatc ccccggccaa
   102781 tcatgatgcc atctacgcca tatttttcgg ccaattcttc tcctgtctgg cgatctggga
   102841 tatctccgtt gatcgtgatc agtgtttgcg gagcgatttg gtcacgtaaa gcaatgattt
   102901 tagggatgac ttcccaatgt gcatctactt tactcatctc tttacgcgta cgcaaatgga
   102961 cagaaagatt ggctatatct tgatgaagta ggtgactgat ccattcttcc atctcagaca
   103021 tttccgtata gccgatacgc gtcttgacgc tgacaggcaa accgccagct ttagccgctt
   103081 caatcaattg tgccgctact tctgggcgaa ggatcaagcc actgcctttt ccacgttctg
   103141 ctacattagg gactgggcag cccatgttga tatcgattcc ttggaagccc atttctgcca
   103201 tagcaatgct catttctcta aaaaattctg gcttgtctcc ccaaatatgg gcaaccatcg
   103261 gctgttcatc ttctgtaaag gtcaatcttc ctcgtacact gtcttttcca tctggatgac
   103321 agaaactgtc tgagtttgta aactcagtaa agaagacatc cggtgctgct gcatgcttta
   103381 cgacatggcg aaatacaaca tctgttacat cttccattgg tgctaaaaca aaaaaaggct
   103441 ttggcagctc tttccaaaaa ttagtagtca tttatttgtt actctccatt ctatcaagca
   103501 gtgaagtcgc aatctttctc aaaaacattg tcattatact aggaaacaaa aaaagaagca
   103561 aagtgaacag cttaaaagat gtttctgatt gagcaaaaaa agactgtgac aaaaatctta
   103621 tcacaattcc ttttccggaa taaatggtgt tcaaaagctt gcatctgcgg taataagtcc
   103681 aaccaaacga aaaataggag gagctatttt tgtttggctg ttcttattac ttgatgcaga
   103741 acagcttttt cacaacctct ccactaaacg gtgttcaatc agctgaccct cggtattagc
   103801 tcaacaaacg acaaaatatg aggaactatt ttcccgtttg tttctctaat actcaggtca
   103861 aaacgctgat ttcacaacct cttttctaac ttctcaatcc tcttccttta ttgatcaaat
   103921 accaagtaac ggcgtacaaa acaacgatga atagcacaag tacgatcatc gatgttgcta
   103981 ctggcacatc gattgttcca aggaatccgt aacggaaacc ggagatcata taaacgatcg
   104041 gattgacttt cgaaacagct tgccaaaatg gcggcaacat agagatggca tagaaaacgc
   104101 cacctagata agttaacggc tgcaagacaa atgtaggcac gatcgataca tcgtcataag
   104161 actgagcaaa aatcccgttg agcagtcctg ctaacgaaaa caagattgcc gtcatcaata
   104221 atgtaatgat gaccatgaac catgaataca catgaagtgg tacaaagaac aaggaaatga
   104281 tcgttacgag agagccgacg agaatactgc gacccactcc gccaatcaca aagccccaaa
   104341 tgatcacatg cgtaggaaca ggcgctacca agatttcttc gatgtttttc tggaattttt
   104401 gagagaagaa ggacgaagaa acgttggcat acgaactagt gatagcagac atcataatca
   104461 aaccaggcac gatgaattcc atatatgaaa aaccacccat gtcaccgatc cgaccaccga
   104521 tcatttttcc gaaaataaca aagtacaagg atgtcgtgat cacaggcgga accagtgttt
   104581 ggacccagat acgcaaatag cggttcgttt ccttgatagc taaacttttt aatgcagtaa
   104641 aataaagatt aaacattttt ctcctccgta tgattatttt cttctgtgat tttcaaaaac
   104701 agttcttcta aacgattcga cttattcctc atagaaagaa ctttgattcc ttgtcttgtc
   104761 agctgatcga agattccgtt caccccttga tttcgttcaa cttcgacagc gattgtctgt
   104821 tcatcttcaa atgtacaagc gtatccttca atcacaggtt tggtctcata tggcgctaaa
   104881 tcaaagataa atgtttcaaa ttgcagtttg gatagaagct ctttcatact agtattctcg
   104941 atcagttcac ctgattggat gatcccgatg ttgcgacaaa gcatttcagc ttcttctaaa
   105001 taatgcgtcg tcaaaatgat cgttgtacca ttttcgttca attctcggag aaactcccac
   105061 atctcgcgtc tcaattcaat atcgactcct gctgttggtt catccaagat cagcaaacgt
   105121 ggttcatgca tcaatgccct agcaatcatc agtcttcgct tcattccccc ggaaagcata
   105181 cgtgcacgga catttctctt ttcccaaaga ttggactgct tcaaatattt ttcgctgcgt
   105241 ttcatcgctt ctttgcgaga gacaccgtag tagcctgctt gattcacgac gatttgctgg
   105301 accgtttcaa agggattgaa attgaactct tgcgggacta atccaatctg ttgctttgct
   105361 cggactagat ccgtatccag atcataaccg aagacattca cttttccaga tgttttattg
   105421 actaaagaag taatgattcc gatcgttgta gacttcccag ctccatttgg tcctaatagc
   105481 gcatagaaat ctccttcttt cacggaaaga tcgattcctc gcaatgcttc gaccccactt
   105541 ccataaacct ttttcaaatt atttatttca agcgcatttg ccatttattt cctatctcct
   105601 tatagacatg attctttatt gtatcatgga atacagcaga tgaaaaaaca acttggttcc
   105661 agcgaaaaat caggttgctg ggctcaggaa aatctcctaa tgaaagacat caatcggacg
   105721 aagtcagaca accttttcag aaaaaacaaa tcgaagataa aggattacta ttcatatgtg
   105781 caacaaaagg agcgtgagac aaaagtaaag aacacttttg tctcacgctc taaacacgta
   105841 taaacggcgg aagcaaaagc caagattttt gatccaataa atactttcga tcacttcgcc
   105901 tatcccaata catgccactg ccgcttttca tcaaataacg cggcttccgt ttttgcggtt
   105961 tctactaaag tctctgggta atccaaaact ttcagcaagg caatcgcatt tcgggtcctt
   106021 gaaggtcctt cttttaattt gaaatcaaaa ctgattcctt ttccttctgt tacttgttct
   106081 tcaaagtgga cattctcaca ataattcttt aaaatctctg tcaattcgat atcatgtgtg
   106141 gcgacaaatg ctaaagatgg atactccgca agccaccgaa cgactgaagc ggaagaagca
   106201 atccgttcga tcgtatttgt cccttttaaa atctcatcta cgaagcagta gcagcgttct
   106261 ttggaagcca cttggtccaa caaacgtttg atcgatttga tttctgaaac aaaataactg
   106321 tcgccttcaa ataaatcatc ttcgattgcc atggaagtca acacatgtcc aggttgcagg
   106381 gtaaactgtt ctgcaatcgc tgtttggatc gtctgtgcta gaatacagct gatggctata
   106441 cttttgacat acgtagattt tcctgatgca ttggaacccg tgactaatgt attcttctgc
   106501 cagttgaccg gattcactac cgcttctttt aacaatggat gatagatatc tttcgctgtc
   106561 acaccgccct cagtaaactc tggtcggcaa gtgatgggca tataagtacg gtaattcaat
   106621 attgcagcgg ctacttctaa ttctcccagc aattcccaca gcttgatggc ttcagttgaa
   106681 tgcttttcta atttagtgag aacgaaatga taggagataa atggcagcat gaacatgatg
   106741 ttgacatatt caaaaatcaa ctctgcttca ctcccactct tcatacgaaa tgaaaaacct
   106801 aatttaggga tgtctcttaa tggtttagtt tgctgtttca gctcttcttg aagtggtgtc
   106861 ggcagttttg ctagctgatt ggcggctgaa atcgttgaaa ccaaataact catgctattc
   106921 agctctgttt ctagtgtttg tttcttcact agataataga ccgtattgaa tactaaccca
   106981 ccgattgcca aatagattcc tagtacttgt cctaaaagaa gcaaacccaa acccaccagc
   107041 ggaagcaagc caagaaaaat aaataaacct acgcgtccaa tctttttact ttttccatcc
   107101 gctagatatt gttttgcaaa attatgatct ttttttccta aacgagcgaa ttgatattgg
   107161 attttttctc tcagttgagg attttcctga taaaaagcaa tcagtttttc taactgctga
   107221 tcttcaccaa aatcaaagct gcgtaaacgt tgatacaacg cttctgaacc tacactagaa
   107281 taggtactgt tgattccttc gaatacttcg aacatatcca ggtcatacca agtaagatca
   107341 tcgatttcgc tatcccatga acggaacttc ttctccgtga gccatgcttc cttcaagctt
   107401 tcttctttat caaatctcgg ttgataagga attttttccc atttgctacg aactgtttcc
   107461 tttaatttca aacgtgaaaa aatgtctaaa gcaactaata aaataacagc tgcaataata
   107521 attaaaacga taaattctct ttgacccata tccctctccg ttcctttatt tgttagcttt
   107581 agtatagcac tgttgcgcta tttgaaaaga gggtaaaaaa acacctttca aaataaaagg
   107641 tgtttttttc ttgtatatta catatttatc tctcatttat caaaattgac aaataatcat
   107701 agggaggaat tgttgttaat tcttgtttat tctccagtgc attgacaact gtcccaaggg
   107761 aaaggatagc ctcaggtact attttttctt gttctgttgg attagctaag cgaagaacaa
   107821 atccttgttc atgaaaataa gaaggataaa tcgatgatac aattaagtct tcaggtaatt
   107881 caatcaatga aaatttacga ggaacatcaa gttcattttg taatggccaa atcttgttat
   107941 ctaacctgtg aataaataca ttcagtttct gcttttgata agaaatagat tgttctaacc
   108001 gtttttctgc ctgttttgcc actttgaact cattaaatct tccttcttct acattaaatc
   108061 caaaagtgac tttatactca cctatctctt gagctagcgg tgtttccatc atgacatgcc
   108121 cttcatttgt cgtatctcct gaagctcgcc caggtcgcca agcaagatta ggttttccaa
   108181 gttcccctgt tgttgaaaat aaggttatga ttaattgatt ttctatacgt tcatactctt
   108241 ttaaaccatc tgcataaaac gtaaaataat gatcattttc tgccacagag acactcttat
   108301 cgaatatttc taaattaaca ggtttctcta ccatagtttc tgaccaattc ggaggaatga
   108361 catcaggggt attttcaata aatccgtttt gaatttgtgc aattgatttt tcagatttat
   108421 ctaaaacatt aattgctaag cgcatacgat gcgagtaaac agtattatga attttgagtg
   108481 tgccttcaac gatttgactt tctcccagac tgaacgatat ttcataagat atttcttcca
   108541 tttcgggttt ttcagataaa cgatctttta aatctttagg aagttgagct tttccgtaaa
   108601 caactaatgt ttcttgtaaa gaatctttat atactttagc tgtttctaat tttagagata
   108661 gttctgtatc tccttctaat ggtgaataat catacgtatc gccatcattt gctgaatcga
   108721 tcaaatgaac gaaatcaaga tattgtctat ctccaactat caaattcaat tgcccatctt
   108781 taaaagaaag tttatattta ttgttactta tctcagtttt gtctatctcg attgctgttt
   108841 ctaatttttc attatttttc tcaaattcaa caacagtgta tcctagtgct ggcacattta
   108901 catttatttt tatgtcaagt tcataataag ctggttcatc aaaatattcg aaacctgtag
   108961 caatcatccg ataagcattt ttccgttctg gaaaataaac ttctttttca atgatattat
   109021 agggactacc tttgaagtgt attttctttg aatcagctac tacatgcacg attttcgatc
   109081 cactataatt ctcagtcgtt gtgttgaaaa caaggacttc attcgatttt agctttaatg
   109141 catcagccat ccgttttaca ataaggtttt cgattccgtc agctatctca ttagcttctt
   109201 tgattcgatg gaaaatatct tccgcaacat tatctgaaac acagccacca atactatcat
   109261 gagcctggtt ttgcaaaatc tttttccata accgacgaag taggccttta ctgatatgga
   109321 taccatttct ttctgcaatc agcatgagcg gctcaactcg ttttagaatt ttttgttcca
   109381 atttaaaatt ttctattttc atttttgttc ttactgagcc aatagaacga tgaacacgag
   109441 agtaaaccgg ctgacgaagt tcacctttat attcaggtaa ttcttttttg tttctgataa
   109501 cttctacata agaaggataa tctgaaataa tattgtggaa tttactgtat ttattcaact
   109561 tctctacgac ttgatcaaaa tttaaaatca ttgacttttg atctacaccc gaaggtacta
   109621 aaatatcttt gttttttcct tgcatatgaa gcatttcaac tgcttcatcc aacttttctt
   109681 ttgcaaattc aggaatatct ttaattgcgt ctaaggtcat cattccagtc atataaccaa
   109741 atggaaaatt catggcataa acaaatttat ctcccaatcc tttccagata aaataaggag
   109801 atggaaccat cgtttcaaag tttaatcctc gccaacacat gaaattatcg atttctactt
   109861 gatgcaaaag tgtaggcaaa ttcgcattga acccaaacgt gtcaggcaaa taccctacca
   109921 tcattggatc tccatattta aggatcgtat cactgattcc aatcattaag tttcttaaaa
   109981 ttgattcagc atccactaat aaggcatctg tttgtgcata ccacggtccc acgaatagtt
   110041 gtcctgtttt catcagtcgt tggataacct taagcttttg cggattgatc tccaaatact
   110101 catcgacgat tgaagtttgt ccatctaaac aaaagtttac tttagggttc ctttccaatt
   110161 catctagaac ttcagtaaag acctgatcag acaatacgat ggcatcttca tttgtaaaat
   110221 accattctct gtcccagtgc gtgtgttgaa ttatatgtgc atttaccata tcagattctc
   110281 ctactttcct tcttctactg aatttacttg ttgttctttt ttatacttga tggattttag
   110341 tgcattgacc attaacgctg taaccactcc cccaataaca attgatacta aatataaagg
   110401 tatattcgta acaaaaggaa ttgccataaa ggttgaaagc attgtttctt gagtaacacc
   110461 aaaaaatcca tttagaccac atgctactgc agtgcccacc acgatgcttg gtattactcg
   110521 taaaggatct ttcacggcaa acgggatcgt cccttcagta atccccacaa ggcccataat
   110581 catagctgtc tttgcattat ctcgttccga ttcatcataa agttttttgt ttaaaattgt
   110641 tgctaaaaac attccaaatg gcggaatagc aattcctaat aacatggctg tactaggtcc
   110701 aaagcttccg cttgaaaaag aagcaacccc aaaagcatat gcgattttat tgataggtcc
   110761 tcccatatca aacgccatca ttcctcctaa aatagccgac atcaaagcag catttgctcc
   110821 tgacatgcct tctagccaat tagtcagtcc tgttgtcatt gcttgaatag gcgtagctag
   110881 tacataccat aatatgattc caacaactaa tgtagtaaca aaaggaatca gcataattga
   110941 ttttagacta ataacttgca tcggtacttt tacttttttc aatgcattag ctaaatagcc
   111001 acaagctaat ccagcaacca ttcctccaat aaatcccata ccaagatttt gacacatcat
   111061 cccagtgata aaagctggtg ctagaccggg acggtcagca attgaatatg cgatataggc
   111121 tgaaatcatc ggtacgataa actgtaatcc cgtctgacca atcattcgca ggactcccca
   111181 gaatgtatcc gtctggtccc aaacacctgt gccaccaaaa atgactgcaa tagaagttag
   111241 taaccctgct gctacgacaa gcgggatcat ataggaaacc ccactttgga aatgatttag
   111301 aatttctctt ccttgtttct tgaattccat tagtaactcc cccacgatat attttttatt
   111361 tgttaattaa tgcaattgct tcatcaatcg tctcttcacc atcttttact acctctgagg
   111421 tccctactgt taaaatcggt ttaccgtcaa agcgacctcg ttctgaaaca tttgtatcta
   111481 ctgcaaatat gacaacatct gcctcggaaa catccgaaat tgaaagtttg ttttctatcc
   111541 ccatagcccc ctgtgtttct actttaatat ctaacccttt cttcttcgca aacttttcta
   111601 aattagcttt tgccatataa gtatgggcaa tccctgcgat acatgctgtt actgctacta
   111661 tttttgtcat atgaaattcc tccttttaaa atgatagagc ttttaccaat tcttttttat
   111721 ttctcgaatc ttttattctt ttaacaaact cgtcatccat caatcttcca gataattctg
   111781 ctaaaatacg taaatgatta gtacctttat cagtgtcttt tattgctaac aaaaagacga
   111841 gatcaactgg ttgatcatct aatgcgcccc attcaacaga ccgctttaac ttggctacag
   111901 ccactgttga ttcaattact gctaggcttt tgccatgagg aatggcgata tttttcccaa
   111961 ttcctgtggt catatggttt tctctgtcaa atacgtcttt ttgaaattgt ttgtggtcag
   112021 acacaaaccc attagtctct aacaatttcg ataatttttc gactacactt tttttatcag
   112081 atgcatttaa atctatcact atattattta tattgatttt ttcactgatc atttataagc
   112141 cttctttcaa tatataaact aatttttcaa acgacgaact cgtttttaaa tttgctaata
   112201 actcatgatt cgaagcgatt tcattgaatg tttcataaat tttattcaat tcaggtttta
   112261 ctttttcatt aagtgcaaaa aagaaaacag aatgaacaag tgtcccatcc caatcaattc
   112321 cttctggatt aacgtagaca cagattactg gcttttttat aaaatctact tcgatatgcg
   112381 gcatagcaaa atcattcatc gctgttgaag atagtttttc tcttttgatt gctccctcta
   112441 gtatcccttc tttcgcgtaa ttttctttta ccaatttttt ggtaattata tttaaaacgt
   112501 tcacttgatt atcctttatt tggtgggtaa aaaagcaaaa tcgtttatct aataaattta
   112561 gaaaagcatc ttctgtttgt tcatttaact gtagatactg ttttactttt ctgacatctg
   112621 cccctaacat caaaggacta acaacaataa caggaaaatt tgtattttca atcggaatcg
   112681 tgcttataac aagttcatca gtgacttttc tatcttgtag ttcattgatg cttagtacat
   112741 cttctatctc aaccatatct gcaaaaccgt tatttattct ttgctctaat aattttgatg
   112801 ttccatatcc gctactacaa actaatatca ctttcgtttt gtcaggtttg taacgatcca
   112861 aaagtgattg aatatggagt gttacgtaag cgatttcatc ttcattaaaa tgtatacaga
   112921 atctctcttc gatttcctct aataaatcta cacttatcat aaatgacctt ttaaaagaat
   112981 atttgatttt gtccgtataa gggttataga tatttactcc caatttgagt cttttaactg
   113041 ctgcattgag atgtaatact agattattga tcaattcttc atcaggataa aattcattta
   113101 atttaattct tactaactct tgtagctcaa cacccatatc taaataggaa agcttcgttt
   113161 gatctaagtc gtgattcata gcattttttt caatcgaagt aatgtgaatg tcaacataag
   113221 cttgttcatc tattggcaca ataattgaaa atgctttttc aatcattttg attaaaataa
   113281 gtgtattctt tgagatttct tcttcagaat tattactacg tgataagaaa ttgcttgttt
   113341 caatcctttc tatcgcaata gcaaggtgga tagctaaagt ttgaaattca taatctgtaa
   113401 atttcaattg tgtcttattc atgtatcgat taagcaattc ggctactttt ttcaatatgt
   113461 ccttatttaa gaaattattc gcttcaccaa tgaaattgat attcaagtct aagagatctg
   113521 ttttactgtt agatgctgta aagccacccc aataatagtt cacaacttct gacatcaacc
   113581 ttcttttact tttttcatca gctttgatgc gcacgccatt tcgatctgaa actaaggaca
   113641 tcccatgctt gtttagtctt tttctaacat ctttcattgt gctttctacc gtcgacctgc
   113701 tcacgtataa ttcgtcagca agattttgaa tctttagaga atcattagta ttcaataatt
   113761 tagcaaacac ataagttaga cggtcctccg gagagtctgc gatattgatt ttatgactgg
   113821 ataataaatt tcgaagtgtt tctttttttc caataagcga aacgcctttt ttaggttgaa
   113881 ccaacatttg tacatctggc attttttgga ttatttcttt caaaattaaa atatctttgc
   113941 taattgtttt cgtagataca tataattgtt ctgataattc tttgtaagtt gtgtgctcat
   114001 tttcaatcaa aaagtatagt attttcattt gccgttcgct aaattcgatg cccattatct
   114061 tcacctcctg aatacagctt aagtgtacaa ttattatctc tattttcata cagaagaaag
   114121 ttcttgatta atgtagaagt ttctaatatt cttgattatt tcaaatcaat aaaaaagcct
   114181 gcaatattta tatcacaggc ttttttctct attaaatata tataagataa tacatttttc
   114241 tactagttct cactaatctt gtataattaa accctccgca acttgacgga gatggagaag
   114301 atgcccccgt ctaatctagc ggtcatctct cctcccattc cttccaccaa tttttttgac
   114361 aggtaaagcc cgattccgct agattccgta tttgtgcggc tggtattttc ggtataaaaa
   114421 cgctggaaga ctttttcaac agaggtttgc gttcctggtt tgataggatt ggccactgtt
   114481 aatcgaatga atggatcctc ttttgaaaat gtcacctttg cttgtccatc tgcataacgc
   114541 aataaattct gtatgatatt ttgcagcact cgcagcaaca tgagcggatc tgctaataca
   114601 gttgtattta tcgagtgttc agcgaacgct acctcgatat ttttctcaga aaattgttca
   114661 taaaaagaga aaaatacttc ttccacctct ttagaaaaag aaagcgtatg gagatccatt
   114721 tctttttgct tcgtctctat tcgagcaaga tcataaaact gatccgtcat actgagtaat
   114781 cttgcaacag attgtttgat gatcgttaaa tacttctccc gtttctccgt atcctctacc
   114841 tgttccagta attgtacata accgttaata gcagtcaaag gagttctgag atcatgagaa
   114901 aggccgacga tcgatagtct gatgttttct tccatttctt gaaatgcttg tcctttttgt
   114961 tcattttcat ccaaccatgt attcagtgca tctactaggt ccattagatt cttttctcga
   115021 aattcgactg aaagacgacc accatattct tgtcgttcag aaagagtggc gattttctta
   115081 gttaatctct tgatttccct ttgcaggaag aaaataaaac ttcccataaa gataacaacg
   115141 agaagcaaca gccatttaat caaatctaaa ccccactccc cacaccgtat gaatatacac
   115201 agcatgtgcc tttgctagct tccctcgaag attggaaata tgcatattca ctgttttctc
   115261 actatcaaaa tatggttctt gccaaactgt ttcataaaga tttgctcgcg aaaatacttt
   115321 tttcggatgt tctaaaaaaa gcttcagcag atcgaattct cttcctgtca aatggacagc
   115381 cacaccattc acatttacat ccctcgactc tttgtccagt aagatttcct tgtaatagat
   115441 gcgttgcgac agatctttta cttggacaga agtctgatga cgaagttgga tgccgattcg
   115501 taacaaaagt tcttcgatat caaatggttt cgtcacatag tcatccgctc ctgctgccaa
   115561 caaggaaact ttatctcttt gatcgctttt tgctgaaaga acgatgatcg gaacattcga
   115621 tgtctgtcgg atttctgcta acaatgcttc acctgaaagc cctggaagca tgagatctag
   115681 aaggatcaaa tcgacaggat atgtgcttaa caataatttt ccttccgtac ctgaataagc
   115741 atcaagaagt ttgtatctct gttcaagaac ctcctccagt aaggaatgaa cagcttcatc
   115801 gtcttcgata atcaaaatag tttccagcag gaccacctac ttaatgtcag atttttggaa
   115861 aataaacatt cctagagctg atgataccac gattgttact agactgacca gaatcatttt
   115921 cggtgcttgc gaataagttg cttgttgcgc aaagtccgta tacatgagcc acgtttccgt
   115981 aaaccactcc gttagaaatt ccaagccttt gatttttgcg aaaacaccgg gaatgaaggc
   116041 cgttcccatg atataaagaa aagaaagaag caaactgaca ctggtacttc tagtgatgaa
   116101 tgtcaaagcc actggaacag ataatgtccc taatgtcagc agaagcaata caggaaatac
   116161 ttttagaaca taatttccat agtttttgat tccctcaact tcaccaaatc cgaaagcaag
   116221 tgtgtaagca agcatggcta gtcccgtgat caaaaccacg ccaagtgttg tgatcaaaag
   116281 cgtaacgaga agtttcgaca cataataagt cattcgattc cgtcctaaag ataacgtatt
   116341 gcgaatcgta ccgttttgaa attcttcccc aatataaaag cacgcaaatg ctgcgaaagc
   116401 cagaagaatc catgcagcca ttttttctac cattaaaatc cctgttgcac cgttgatgac
   116461 tgtatccgtt gcttggttta attcattgcc gtattttgta tgcatatacc attcgttcca
   116521 agaataaaaa agcggaagta cgaccatcag tcctagtgag acccacattt tacggctctt
   116581 ccatactttt attttttcag cagttaatag attaaacatg tggattgcct ccagttaatt
   116641 gtaagaaata atcttccagt ttttgcccaa ctaggtgaat accatccaca ggaacttttg
   116701 cttctaccaa tgcttgattg atggctgcta cttggtcaat tccttcaaaa agctggataa
   116761 cacggctaga ttgtacaaaa taatccctat aaccaagaga gtcgagaacc gttactgctt
   116821 gttccgtcgc cgaagtgtca atttttataa attgacgaga ttcttgtgcc aattcttctt
   116881 tcgataattc tttgatcaag tgtccttcat gcaaaatacc atagtgagtg gcgatctgtg
   116941 acaattcatc tagcaagtgg ctagaaagca agacggtgat gccccgttct tttaccaaac
   117001 gttggatgat ttctcgcatt tctgccatcc ctgctggatc catcccattc gtcggttcat
   117061 ccaaaatcaa aaattctgga ttcgtgatca gtgcatttgc aatagctaaa cgctggcgca
   117121 tacctaaaga gaaattcttt gctttctttt tccctgtatt ttccaatcgc atcattttca
   117181 gcaggtcttc gatttctcta tccgacacac cgccgttcgc tgcttggata cgtaggttat
   117241 ctcttgcagt taattctgga taaagagcag gggtttcaat cgattgaccc atacgtcgtc
   117301 ttgctgcctg caaatccgtc gttccaaata attcgatcga accttcatca atcgagatca
   117361 aacccataat agttctcata aaggtagact tacccgctcc attttcccca atcaatccat
   117421 agatcattcc acgtttgatt tcgattgata ctttatctaa tgctttggca gcaccgtatt
   117481 ttttggttat accagttgct ttcaagaccg tttcatttcc aaaatccata cttatccttc
   117541 tttcttattg atgagtgaag tatagttgac gggtataaag aaagcagcca gaaatgtata
   117601 aagaaagtgt aaattttcca attgaatgtc aaaaaaaaca atcggacaat acgtgtcttt
   117661 cctattatca ggcagtttgt tatacgcttg tatcagtttc ctgattcttt cttttcgacc
   117721 aaagtcgttt ctctgtattc ctcttcactg aaaatttttg cttctttcag atcaagcttg
   117781 agtaatttta ccagaccggt tataaggata actatagcaa gactccctcc cagaaaaatt
   117841 agactgtctc gcagacgtgg ttgcgttgtc ttccaatcaa agagcgcacc aaacagtgct
   117901 aatccaagtg gactggccac catggtaatc gttgttatcg ttgacataag tcgtccttgt
   117961 atatgcgttg gaacttctcg ctgaagccag accatataaa aagcaaaaga aaacattaat
   118021 ccttaaaaac ggacttatga aaaataatac atgccgtttg ggatttacaa ttagctacca
   118081 aataagaggt tatgacaaaa gacttttcac aatcccttct tccgaataaa cggtgttctc
   118141 ctgccaactc ctcggtcaca agtcacaata tttatcaaac atgagaagca atttttgtaa
   118201 attccttctt atttcttgaa gctgaccact tctgtcacaa cctcagaagc ggataaataa
   118261 tattgtttga tgatacttta tctttttccc gtttgtttat agatcgaatg atattataga
   118321 ccaagaatcc tacctattaa catagctaaa aacacaaaaa aggcactttc caaattgtgg
   118381 aaagtgccag aaaagttagg attaaggtaa ctgcgctcag cattgcttcg cccagtacga
   118441 ttctcgtaac tcgtgaactc gaacgataat cgcaattaac gttttgagaa ctgtgaagct
   118501 ttacgggctt tcttaagacc tggttttttc ttcgtatcat tgaataagtt tgaaaaacct
   118561 tgatttataa aggttttccc gtaaatatat tttattatat ttgattaaat ttgaaatgtt
   118621 tgtgttctaa aatgtgttct aatttaaagg cagtatattt cgtattttag attaaatttt
   118681 taggctcatt cattctcaaa tccattctat tcagtcaata aaaattttaa aaagacttta
   118741 taaacaaaga tgttcaagcg agcatcttat ttttttgtgc ttaatttgaa aggagaacat
   118801 ttcatgtata aaaaacaaaa aaagaaatta tgtgtattaa ctattttgag tttggctgtt
   118861 caagcaattg ttggagcaat tgctcctacg attacttttg ctgatgaaat tacccatcca
   118921 caaacggtaa ccgtagaact agatttagca catcaatatg ctgttgaagg aacttttagt
   118981 gatggtcgtc caatgtcaga agtcactgtt ccgcattatg cagtgtacaa cggctttaaa
   119041 caagatattt tctgtattga accaggagtc ccgatttaca atgagttcac tcctggctat
   119101 gagaaaaacc cgttaccaga tatgtccgat aaagccaaat tagtttccgt tttatggaaa
   119161 aaagtaggta cagatgcaga tactcatatt gtggcacaga agatgatctg gcaagaagtt
   119221 aatgggtata cccttcactc aataaaacga tcagatggta gtgccgtaaa tatcgcagcc
   119281 attgaggcaa aaataaatca agccattgac gattatcaga agaaaccaac cttccataat
   119341 agtacggcta aaacagtatt agggcaatcg actactgtga cggatacgaa taatctgaat
   119401 ttgtcagagt tcgatgaggt tgtggaaaat gccgcaaaca ttgattatcg tgtgaatggt
   119461 aatcagttga taatcacccc aaatgccaat tcaaaagaaa gtggtgtgct gacgcttaag
   119521 aaatctgctg gtaccggaac acctgtcgcc tataaaaagg ctggccaaca gactttaatg
   119581 gccggggcga ttgataaacc taatacctac acaatcaaaa ttgatgtgga aacggagggt
   119641 tctttaaaga tcaaaaaagt cgataaagaa tcgggtgatg ttgtaccagg aacggttttc
   119701 catttagact ttggaaaaac tttacctgca aaagacgtga ctactgacaa agaaggcatt
   119761 gctacattgg atgagattcc tcatggtaca aaagtaacca ttaccgaaaa atcagtaccg
   119821 gcgccttata cgattgatac cacccccatg actaccacca ttaaagcagg cgaaaccatt
   119881 tacgtgactt caaaaaacgc acgggaaaaa gggcaaatca ttctggataa aagcggagtt
   119941 gaaacaggga gtgatctttg gaatgacaat tattccttag ctggtaatac gtttgccatt
   120001 cgcaaagaca gtccaaccgg tgaaatcgtt caagaaatga ccacggatga aaacggtcat
   120061 gcggaaacac caaaagagat tgctaatgcg ttggaattgg gaacctatta tgtgaccgaa
   120121 actaaagcta gtcatgggtt cgtgaatacg ttcaaacctg taaaagtcga attgaagtat
   120181 gccaatcaaa ccgtagcccc tgttaccagt aacgtaaaag ggcaaaatca agaagtcact
   120241 ggcgaaacca ctttgacgaa agaagacaaa gatactgggg ataaagcaca aggtaaggca
   120301 gtctttgagg gtgctgaata caccttgttt actgctaagg atggaaaagc tgttaaatgg
   120361 agtgaggctt ttaaaccaga gttagcgaag ggaacgaaag gttctgatga aacggtcact
   120421 ttgactttag acgaaaagaa ccaagttgcc gttaaacatt tagctatcaa cgagtattat
   120481 tggcaagaaa caaaagcgcc cgaaggatat agccttgatg aaacaaagta tcctgtatcc
   120541 atcaaaaagg tggatgatag cgaaaaaaat gccgtgatta cccgaaatgt tacggcaaaa
   120601 gaacaagtga ttcgctttgg ctttgatttc tttaaatttg ctggatcagc tgcgggcact
   120661 accgaaactg gcttcaatga tctgaccttt aaagtgtcgc cattggaagg gaccaatgaa
   120721 atcacaggtg ccgaagatga agcgaccaca gcttataacg agcaattagg gtttgatggt
   120781 tatggcaagt ttgaaaatct tccttatggg gattatttac ttgaagaagt agaagcccca
   120841 gaaggttttc aaaagattac gccattagaa atccgttcta cttttaagga aaacaaagaa
   120901 gactttgtga agagtgagta tgtctttacc attaccgaac aagaccaaaa acaaccaatt
   120961 aaaacggtga ccgttcctta cgagaagctg acgaacaaag cattttctgt tagtttgaac
   121021 cgtttaatgc tctatgattt gcctgaggaa gaagatagtt taacttctct tgcgacttgg
   121081 aaagacggaa acaaagaatt aacttctctg gattctaccg agctagttga taaattgagt
   121141 tacaatctac atgaaatcaa agaagactgg tatgtggtag cgcaagccat tgatgtggat
   121201 gcgacaaaag ctgcccaaga aaaagatgaa aaagccaaac cagtggtgat tgcagaaaca
   121261 agcgcaacgt tggcgaacaa agagaaaaca ggaacttgga aaattcagca taaattaacc
   121321 gccgaacaag ttttaaataa aactattgtc ttattcaact atgtgtatga aaataaggaa
   121381 gcttttgaag caggcgataa gccagtagcg aaggatgtta gcttgaataa ccaagcccaa
   121441 actgtcagtt gtacagtgga acaccatgtt tctatccaaa caaaggccca cctagaaaac
   121501 ggttctcaga cctttactca tggtgatgtg gtggatatgt ttgatgatgt gtcgattact
   121561 catgatgtac tggatggctc aaaagaagct ttcgaaacaa ttctgtatgc tttattaccg
   121621 gatggtacaa acaaagaaat ttggaaatct ggcaagattg attatgaagt aaatgataaa
   121681 gaattcacca aaactgtgct tgcgaaaaaa gtagataccg gaaaatatcc agaaggaacc
   121741 aagtttactt ttgcggaaat caattacgat aaagatggga atatcaatgg aaaacacaat
   121801 gaagatttga aagaaaaatc tcaaacctta acaccaaaag aagttccaac catactaagt
   121861 acgccgaaac aaccggaaac accaactgtt ccaagtggct ctcaagaatc tagtcccaca
   121921 gtgaagacct tccctcaaac cggggagaaa aattccaatg ttttactgtt cattggtttt
   121981 actttgattt ttgcgacggc gggctattat ttctggaatc gccggaacta aggtgatgag
   122041 atgatacaag taaatcctaa gaaccaacgt gcgcgaccgc ctcctaaaaa agtagtcgcg
   122101 ctatttttgt atccaaaact aacaatgaaa agaggaaaag aagatggaat tgaaatttgt
   122161 cgtgccagat atggctgaaa cctttggaaa gttaagttat gccggtgaag gagaaattat
   122221 aacagaagga tatggacgga atactacggt gattggtcgc agttatcatt tgtattccag
   122281 taagcaacgg gccgatgata ttgaggtggt agtagctgcg gaagccggtg aaaaggattt
   122341 tgatcaagac caaccgctaa aagccgtgaa tccccatttg gttgccaaag gctatgagat
   122401 tgagaatcgt gggtttactg attacgtgtt gtatgttgat gatttagtga aagcatagga
   122461 ggaaaagaag atgagattaa cagaaggtat tgtcgtagat tcaggtttaa catttgggaa
   122521 gttgcgtttt tccgcattac gccgagaagt acggaagcaa aatgaggatg gaacaattgg
   122581 taatgaggta aaagaacgaa cctataattt aaaatcctct gcacaagggc gaatgattca
   122641 agttagtatc ccagctaatg tacccttacg cgagtttgct tatgatgcag aggtagagtt
   122701 ggtcaatcca atcgtggata ccgttgccaa ttatgttttt cgagaaggaa ctaccgttaa
   122761 ttggttcatt aaggcggatg atttagtctt gaagcggcag ccgaatcaag gaaatcctac
   122821 gaaccaaaat gaaagaaaga aataggtgaa gattatggaa attaatgttg aacatatttt
   122881 agattgtctc gatcaatatg gaaaaggcga gctgactgag gaacaactcg ttaaagcatt
   122941 aacctctgat gaaaaaatgt ttctgattat acatcaaggt ttacttggag aaaatagcga
   123001 cagtgaagaa gactctgatg tactagactg gttaggagaa gaagagtctt tctttatagt
   123061 tgtcgaagta aatgaaaact tatgtcggca ggcagaatcc attttggaag aaattggtgt
   123121 ggagatgccg gatgctattg aaggcttttt aaatcaattg gttgaaacga aacaactccc
   123181 ctcctcgtag cagtaaatga ctagcataac tttttgaaat tgcctaatga aatcctattg
   123241 ggctttttcg attggaggtg gaaaccatca aaatgtacaa aggacatcgc atacgcgcag
   123301 gagatcagca cttggtttat cactttgttc ttggctggct actcgctctg ttcatcggtt
   123361 ggatgagcgt cttttatttt caagagttta gacaatttga tatttctaag ctatcacttt
   123421 ctactattga aatcgtttgg tctataaaag atttagtatg tctgcttgga agtctcgctt
   123481 tttcaggagc tatgatattg ctttatattc acttttttct tgatcattgg cgaagcttgt
   123541 ggcatcgaca aaagctagct cggatgattc tagagaacca ttggtatgaa gtgaaacaaa
   123601 ctcaaagtga aggctttttc aaagatttga atagtagccg aaccagagag actatcagtt
   123661 acttccccaa aatctgttat cgaatgaaag atggattact gtctattcgc gttcaaattt
   123721 cacttgggaa ataccaagat cagcttttaa aattggaaaa gaagttagaa agcggactgt
   123781 attgtgagtt agtagaaaag gaactcaaag actcctatgt ggagtatact ttactgtatg
   123841 atatgatcgc caatcgaatt gggatagacg aagtagtggc agaaaatggg actctgcgat
   123901 tgatgaaaaa tcaagtatgg gcttatgatt ctttacccca tatgttaatc gctggtggca
   123961 cgggtggagg gaagacctat ttcctcctca ccattatcga agcactattg aagtcagatg
   124021 cagaattgtt tatcctcgat cccaaaaatg cagatttagc tgatttaggt acggtgatgc
   124081 ctcatgttta ttcacaaaag gaagaaattt ctgcttgtgt ggaagatttc tatgaacgta
   124141 tgatggctcg tagcaaggca atgaaagaaa tgtctaacta caaaacagga gagaattatg
   124201 cctatcttgg acttccaccc aactttttaa tctttgatga atacgtggct tatatggaga
   124261 tgttaacgac gaaagaaagt gcggtgattt tgaataagct caaacaaatc gtgatgttgg
   124321 gtcgtcaatc tggtttcttt ctgattttgg cttgccaaag gccggatgcg aaatatttag
   124381 gagacggaat ccgcgatcaa ttcaactttc gcgtggcttt gggtcgtatg agtgaactcg
   124441 gatattccat gatgtttggg gaggtcgaaa aaaacttctt tatgaagcac atcaaaggtc
   124501 gaggttatgt ggatacaggt ggcagtgtga ttagtgagtt ttatacgcca cttgtaccaa
   124561 aagggtatga tttcttagat tcaattagta aattagaaaa gatgaatgat tgagtgatct
   124621 tcaatactga ctttatactt caagtaacgt ataatacttt tatatagtag gaagaaaggg
   124681 gataattaat atggaaagta atgattctta tttagagtat gcaaaagcaa ataaggataa
   124741 gtttatttct tatattatca aagggaaatc ccccgaagtt ggacgagacg cagtttttat
   124801 ggcagggagt cctggggctg gaaaatcaga ggttgccatt ggattagctg agaattatga
   124861 taaccatgtg attattgatg cggattactt tcgcacccag tttcctgatt ataatggaaa
   124921 aaactctagt ctctttcaaa aagcatcttc ttggttggta gagcaggcat ttagatatgt
   124981 cttagatcat ggctattctt ttattctgga tgcaactttt gcaatattaa gtgctgaaaa
   125041 aaatatctcg cgggcgttga aaaaacattt tcgagtgacg attttctatg tttatcaaga
   125101 ccctaaaatc gcttggaaat ttacacaaga acgtgaaatt gcagagggac gtcatgtgcc
   125161 gaaaaaggca tttattaacg cttttttcaa atcaagagag aacattgcaa aagtaaagag
   125221 taaacatcca gatgtattgc ttcatatcat aataaaagat tatacgaata atatttccga
   125281 agttcattat gctacggata atctagaatt atttttacca ctagggtata gtaggaaaga
   125341 tttggaggtt caattacatg actgagaaag aacaagtaac gaaaattgta aagaaataca
   125401 ataagagcat tgcggattta tcggaaaatg ctactgcaaa agagttcaaa acggtgatta
   125461 aatatgtagc cgatcaggcc aatgaaaaac aacggaaatt agttggatta aataaaaaat
   125521 agtaggacaa attaataatg tatgagccaa gagcaaaatg ttcttggctt ttttctttgc
   125581 aatgaatgag gtaatgtatg agatttttag atttattcgc cggtattggt ggctttcgtt
   125641 taggtatgga acaggcgagc catcattgta tcggtttttg tgaaattgat aaatttgcta
   125701 gacgtagtta taaagcaatt catgatacaa gtaaggaggt ggaaatgcat gacatcacaa
   125761 gtgtatcaga tgagtttatt caatccctcg gaccagtgga catcctttgc ggcggatttc
   125821 cgtgccaagc tttttcaatt gcgggaaagc ggcaaagatt ttccgatact cgaggtactt
   125881 tattctttga aatcgctcgg ttcaccactc ttctccgacc taagctttta ttccttgaga
   125941 acgtccgagg attgctcaat cacgaaggag gggctacgtt cgagacgatc ctccgaacgc
   126001 tggatggatt ggggtatgac gtggagtggt aggtgcttaa ctcaaaggcc tacattcccc
   126061 aaagccggga gcggatattc cttatcggac attctcgaga cgcatgtacc gaacaagtat
   126121 ttcctatcat tggaccgtct tcaacatctg atcaaaacat cagaaatttg gtaaatatca
   126181 atccttccaa tcgaggaatg ggtggacaag tctatggttc agatggcgta gcgccaacct
   126241 taacaggtga tgaaggaatc aaaatcgcac tgccagcaag ggatggaatc tctgtagcag
   126301 gactattacc gggaaagttt gaacaaggta atcgagttta tgaagttact ggaaccgccc
   126361 ccaccttgtc aacgaaacaa ggtggtacaa aaatcatgat tcgaaaaaat gaaacagaat
   126421 atcaagaggt gaagccagaa gacagtgtga atctggcttt tcctaattcc acaagtcgcc
   126481 gaggtcgtct gggaaaacag agtgttcata ccttactaac aggagaccaa caagcgatcg
   126541 tcacggatca gtatcaaatt cggaagctaa cacctagaga gtgttggcga cttcagggct
   126601 ttcccgattg ggcttttgat cgagattctc aagtcaattc agatagtcag ttgtataagc
   126661 aagccggaaa ctctgtaaca gttccggtca tttttgatat tgccagaaga ttaaaagagt
   126721 tggatgtaca tggtttatga tgagttgatt ggagaaattt attgggtgat tggaaagatt
   126781 cagtcagacc cagaattaga agaacaattg cgacggttaa aatttgatat tcgcaagaat
   126841 ggtgtcaaag tcgctggcga tccatattta atgaatgagg agacggatgc tcgaattgaa
   126901 ataaatcaag taattgcaga atttgagcgg attgcggacc aagcaaaaga accagatatt
   126961 cgtcaatact tgttagaaat gaaagcagag ttggaagtaa atggtattac agatgagtaa
   127021 cctaaaccaa cacaactgac tgttaggcgc tgaccgcgga ggattcgcga agcagaaatc
   127081 ctccgtggtg ctgtgcctgt tcatggacgg cgttagccga ccatgatgtc tcacccccgt
   127141 atctaacagg ggggtacaaa aacacaaaaa ataagtaagc aaccattaag aatgcttgtt
   127201 gtatcaaaga tagtaagtaa tttgtatagg tgttaactca tttgaaaaag ttaacacctt
   127261 gaatttggag gtgagaactt ggcacaacgg aatttagatt atcggctatt aaaagaccga
   127321 cgcaacgaat acggcgtttc acaaaataaa ttggctacgg cttgtggact tagtcggccg
   127381 tacttaaatc agatagaaaa tggtggcgta accgcatcta taaaaaccat gaggaaaatt
   127441 tttgaccaac tggaaagctt taatcccgat ttgcctttga cgttactgtt tgactatgta
   127501 aggattcgct ttcccacaac ggatgcacga aaaattattc aagaaattct ccatttgaaa
   127561 tttgagtata tgctccatga agattatgcc ttttactcct atcaagaaca gtatgtcatg
   127621 ggtgatattg tggtgatgtt gtctcatgaa gaagataaag gtgtgctttt agaattaaag
   127681 gggcgaggtt gccgacaatt tgaaactttt ttactcgctc aaaagcgtag ctggtacgac
   127741 tttttcgagg attgtctaaa ggccggtggc gtgatgaaac gcttggactt ggcaatcaat
   127801 gatcgagtgg ggctattgga tatacctgag ctaacgaaaa aatgtcagaa ggaagaatgt
   127861 atctccttgt ttcgtacctt taaaagttat cgttccgggg aacttttaaa ggctgatgaa
   127921 aaggacggca tgggcaatac cttatatatc ggcagtctca agagtgaggt ttatttctgt
   127981 ttgtatgaaa aagactatga acaatatatc aagttaggga ttccattaga ccaaactgag
   128041 acgaaaaatc gttttgagat tcgactgaaa aatgaccgtg cttttcatgc gattcaagat
   128101 ttgttaaaag gtcgtagcat tgagagcacc acgttttcca ttatcaatcg ttacttgcga
   128161 tttgcggata aagtagaagg taaaaggcga accaactggc ccttgaatga acaatggggg
   128221 cgttttattg gacggaatcg gaaagagatt caattaactt ccgagccaaa accgtatacc
   128281 attgaacgaa ccttgaattg gctaggccga caagtcgccc ctacgtggaa aatggctaag
   128341 gagttggatc gattgaatcg gacaacctat atccaggata tggtacagaa tgcacgctta
   128401 tcagaccgac ataaaaagat tttggagcaa caaagtatgg caattgaaaa tttgattata
   128461 tgaaaagagg aatcgtcatg ggaattgtaa aagatatttt tttggtattt ggtggcagta
   128521 tgcttggtgt tactgtgatg tgcttgatga atgcaagtgc agcagcggat cgagcaatgg
   128581 aaaagaaagg aaagtgacaa gatgaatttc ggacaaaatt tatgtgcgac tcgttcctta
   128641 gtgaaaagct aaggcactaa taaaagaacg aaaaagtttg gttattagga gaactgataa
   128701 tctgacaggt ggaatgatga agtaacgctc tgaaacgcct gccctgagcc tccgacaagc
   128761 attgtatgag gaaactcaga atgtttgaag ctcggtaaag acggctgaaa gataccgtaa
   128821 tagttgatga acatatatct tctatcgaaa actatccaga ggtgggtagc gtatccaaca
   128881 ggtcgggggt ctataaaata tctatggtta gaatgttcta taaggaactg acgaaacagc
   128941 gaatgtacgg gtctaaattt gaactttgta gaaatgcaaa ggtacgagaa atcgtagctg
   129001 gtgtggcaaa gtaagaatat aggttatgaa atgccatata acgttacagg cggtatcaag
   129061 ccagcaggct tatagctagt gacctaagga tatatatgta tagataagat tatcggaacg
   129121 aggaaaggta ttgggttctc atcaagagaa taaactgacg aagaacaata agcagttgaa
   129181 ctaatgctga aaagcagagg gcgaacctaa gaaattcttg taatgagaat ggaggaatgc
   129241 cctcaagtcg tgtatatatt agaaaagtat tatgttgttt caataaggat tacgagtaag
   129301 ataaaaaagc tcactcaatt tcaagtaaag gagtgaagcc ttatgcctaa aaataaaaat
   129361 gaaacattgt gtgtagaaga tttaagacac gctgaatatt acgaaatgca aaacaccttt
   129421 gatgatttat atgccaaaag taagaatgga gatattttca ctcatcttat ggatattatc
   129481 ctatcgagag aaaatatatt actggcatat cgaaatatca aagcaaatgc aggcagtaaa
   129541 acagcaggaa cagacggtac aataattaaa gatattggca aattgccagc agaaacagtt
   129601 gtcaaaaaag taagatacat tgttgcaggc agtccacatg ggtatcgacc taagccagtg
   129661 aggcgaaaag aaataccaaa accaaatggt aaaaccagac ctctaggtat tccttgtatg
   129721 tgggacaggc ttatacaaca atgtataaaa caagtattag aaccaatctg cgaagctaaa
   129781 tttagtgaaa acagctatgg ttttagacct aataggtcag ttgaaaatgc aataaaagca
   129841 acctataacc gcctacaaat cagccagcta cattatgtga ttgaatttga tattaagggt
   129901 ttctttgaca acgtgaacca ttccaagctg ataaaacaga tatgggctat gggaatacgg
   129961 gacaagcact tgatattcat tttaaaaagg atattaaaag ctccaatcaa aatgactaac
   130021 ggtacaataa catatccaga gaaaggaact ccgcaagggg gaataatatc cccactacta
   130081 gcaaacattg ttcttaatga gttagaccat tgggtagaaa gccaatggca ggaaaatcct
   130141 gttacaaaaa actatgtggt tcatatcaat aaaagcggta gcccatgtaa aagcaacgct
   130201 tacaaagaaa tgaagaaaac aaagttaaag gaaatgtata tggttcgtta tgcagatgat
   130261 tttagagttt tctgccgcta caaggaaagt gctgaaaaag ccaaaatagc aatcactcaa
   130321 tggattgaac aacgattaaa attggaagta tcacaagaaa aaacaagaat tgtaaatgtt
   130381 agaaaaagat actccgactt tcttggtttc aagattaaaa tgataccgag aagaaagaag
   130441 ttagttgtta aatcacatat aagtgataaa caattcaaaa accaaaaaga caagctggta
   130501 tcacaggcaa agaaaattgc ttctccctca aaagggaaaa cggaattaga agaaacaaga
   130561 ctttataatt caatggtatt aggtatgcaa aattattatc agattgcaac gaatgtaaat
   130621 ctggattgta tgaaactgaa tagagctgta atggctatct tcactaacag attaggtaca
   130681 aacaaaaggg gcagattgag aaaaacaggc agacaactta cgacaaagga ggcaacaaga
   130741 tatggtaaat ctaaaatgct tcggtatgtt gctggcgagg gcgaacctat tttccctgtt
   130801 ggatatatcc aacacagaaa accaatggca aaggtgtatt tagcgaattg ctacactcta
   130861 gagggaagaa aatttatcca caccaatcta agtgttgata aattactgat gtaccagtta
   130921 atgaaattat ctttggaaaa tcgcacaata gaatacgcag acaatcgaat ttcgctattt
   130981 tctgctcaac atggaaaatg tgctataact ctggaagaat ttcaacaagc taatgaaata
   131041 cattgtcatc atattgtacc aactggagct ggtggaaatg acgattataa aaatcttatt
   131101 ttggtaaaag aggcggtaca ccgtctaata cacgctaaaa cagaagaaac aatacaaaaa
   131161 tatatagctc tattgaagct aaataaagtc cagctcataa gactaaataa atatagagta
   131221 ttagctggca atcaagaatt aaacttgata taggtctact acataaatac ttttcaatat
   131281 aaacacgatg gaacgcggag tgcggtgaaa gtcgcacgct ccgtgtgaat ggggggaaaa
   131341 gtttgagata tttataatat caggaactta cctatccata tatcaatggt ttttaaccaa
   131401 tgcccaatcc ttagtcttac tggcaattgt ggtcattggt ttgtttttag gatttaagcg
   131461 ggagttttcc aaactgattg gctttttggt gattgctttg attgcggtcg gattggtctt
   131521 taatgcttct ggggtgaagg atgtcttact cagtttgttt aaccgaattg tcggtgcgta
   131581 agggggaagc acgatggaac agatgcgtgt ttatattgcg aacctcggga aatataacga
   131641 aggtgaattg gtgggggcgt ggtttacccc acctgtcgat tttgatgaag tgaaagaacg
   131701 aattgggtta aatgacgaat acgaggaata tgcaattcat gattatgaac ttccctttga
   131761 gattgatgag tatacgccaa ttgaggaaat taatcggttg tgtggcttag cggaggaact
   131821 tgaaggaacg ccagttggtg aagttgcttc tgagattcaa catgctttct tcaattcttt
   131881 tgaggagatg gtagagcatg tggatgatat tatctattat ccagattgcg atgatatgag
   131941 tgatgtagca tatttcttga ttgtagaagc tggtgatttt ggagaagtac cagaacactt
   132001 gaagacgtat attgattttg atgcgtgtgg tagagacttg gagattggag gcaattattt
   132061 ggtaacgagt cgaggtgttt ttgagtatcc atattaacaa aattattgaa gggtagttga
   132121 tttctaaact atccttcttt ttaaaggaat gatttgatga agaaaataaa aagctacacc
   132181 agtatttggg cagttgaaaa ggtcatttat gcaattaatg actttcaact gccttttcct
   132241 gtgactttta accagatggc ttggtttgtt ttatccttgc tgtttgtcat cgtatttgcc
   132301 catgtgcctc cactatctat gatagagggg gcctttttaa aatacttagg tataccggtg
   132361 gcagttactt ggttcatgtc gcaaaaaacg tttgacggta agaaaccatt gggattttta
   132421 cgatctttta ttagctatca cttacgattt aaggtcactt tcgcaggaaa gaaagtcaaa
   132481 gaacagaaga aacgatggga cgaacccatt actctggtaa ggagtgtgaa ctatgtaccc
   132541 gattaagtat attgaaaata atcttgtctt taatcaagag ggagaatgtt ttgcctacta
   132601 tgagttaata ccttacaatt actccttttt gtcacctgaa cagaaatatc aagtccacga
   132661 taactttcgt caattgattg cgcaaaatcg tgaaggcaag attcatgcct tacaaattgc
   132721 cacagaaagt agtattcgtg ccacgcaaga acgatcaaaa aaggaaatta ccgggcgatt
   132781 aacagaagta gcgaaacaac gaattgattt acagacagag gcattagtat ccatgattgg
   132841 cgatagtcag attgattatc gcttttttat tggcttcaaa ctgattgcga cagatgaaga
   132901 ggtcaatcta aagaatctca agaaatcttt cttctccggc tttcaagaat ttgtctatgg
   132961 agtgaatcat catttgatgg gcgattttgt ttccttatcc aatgaagaaa ttcgccgata
   133021 taccaagctt gaaaaactaa tggaaagtaa attggctcga agatttaaag tcagacgagt
   133081 cacaccgagt gatctgatgt atttgattga acatatctat ggcgaaaagg gtacaccatt
   133141 tgaagaatat gaatttcagc taccaaagaa aaagctgaag tcggaaactt tggtgaaacg
   133201 ttacgactta ttacgtccca gtcgttgttt gattgaagaa aagccccggt acttatgcat
   133261 ggaacatgag aatcatgaat catatgtagc gtacttaaca attaatacaa ttgtggggga
   133321 aatggagttt ccctcctcag aacttttcta ttaccagcaa caacaattta cattcccaat
   133381 tgacactagt atgaatgtgg agattgtgac gaacaaaaag gcacttgcta ccgttcgcaa
   133441 taagaaaaag gaattaaaag acttggacaa ccatgcctat caatctgaca atgaaacaaa
   133501 ttccaatgtc ttagatgcat tggattccgt agatgaattg gaaactacct tggatcagtc
   133561 caaagaatcc atgtacaaac tgagctatgt ggttcgagta agtgccgaat cagtagatga
   133621 actaaagcgc cggtgtgatg aagtgctaga tttttatgat gataccaatg taaaactagt
   133681 ccggcctttt ggcgatatga tggggctaca tgaagaattc ttaccttcta gtaagcgata
   133741 catgaatgat tatatccagt atgttacgtc tgattttctc gccggacttg gttttggcgc
   133801 cactcagatg ttaggggagt tggaaggcat ttactttggt tataacgtag atacggggcg
   133861 caatgtttac ctgaaaccgg cattggcctc acaaggggtc aaggattcag ttaccaatgc
   133921 gctagcagcg gcattcctcg gttcactcgg tggcggaaag tcctttagta acaatctctt
   133981 agtttattac gccgtccttt ttggtggaca agctgtgatt gtcgatccaa aaggggaacg
   134041 gggtggctgg aaagaaacct tgccagaaat tgcggatgaa atcaatattc tcaacttaac
   134101 tagtaagcca aaaaatcaag gattacttga tccttatgtg attatggaga aaaagaagga
   134161 ttctgaaagt ctagcaattg atattctgac ctttttaaca ggaatttcta gtcgagatgg
   134221 ggagaagttt ccagtgttgc gtaaggccat tcggacggtt acccaaagca atcaacgggg
   134281 attattacaa gtaattaatg agcttcgaaa agaaggctca ccagttgcgg aaaatatcgc
   134341 ggatcacatc gagtccttta ccgattatga ttttgcccat ttgcttttct cagatggttc
   134401 gattacccag tcgattagtt tagataggca gttaaatatc attcaagtag cggatttggt
   134461 tttaccagat gcagaaacca cttttgaaga atataccacc atggaattgc ttagtgtttc
   134521 catgctaatc gtcatttcca cttttgcctt ggactttatc catagtaatc gagaaatctt
   134581 caaaattgta gacttagatg aggcgtggag ttttcttcaa gtagcgcaag ggaaaacatt
   134641 atcgaataag ctcgttcgtg ctgggcgggc tatgaatgcc ggggtttact ttgtcacgca
   134701 aaatagtgat gatttactgg atgaacgctt gaagaataat atcgggttga agtttgcgtt
   134761 tcgcagtacc gatattcatg aaatcaagaa aaccttggaa ttctttggct tggatcgaga
   134821 agatgaaagc aatcaaaaac gcctacgaga tttggaaaat ggccaatgct tgatgcagga
   134881 tttgtatggt cgggtaggcg tggttcaggt acatccagtc tttgaagaac tcttccatgc
   134941 ctttgatacc cgtccacctg ttcaagagag aatggagtga ggggatgaaa aagaaacttt
   135001 ttcggattgt gggaatcgtt tttattagca tactcactct gatagttcta ttgagtttag
   135061 ttggtacggt agccgaggcg acagggctag ttgatgatac agttgaagca ggaaatctat
   135121 attccaaata ttcactgaac aactatcaac tagatttctt tgtggatagc tcttgggatt
   135181 ggttgccttg gaattggggt gatggcttag ggaaaagcgt gatgtatggt ctttatgcca
   135241 ttactaattt catttggacg gtgagtttgt atttgtcgaa cgccacgggt tatgtggttc
   135301 aagaggctta caaattagat ttcatttcgg atacggctga aagtattgga aagaatatcc
   135361 aaacattggc tggtattact gaaaatggac tccagacctc cggattttat tttgggtttc
   135421 tattattgat gattttagct ctgggggtgt atgtggcgta taccggatta ttaaaacgag
   135481 aaaccacgaa agcagttcga gccgtgatta attttgtgat gatttttcta ctatcgggtt
   135541 cgttcattgc ttatgcgcct acctatatca caaaaatcaa tgactttagc tcagatgtta
   135601 gtgaagcggc ccttaccctt ggaaccgaga tcgttgtacc caattcagaa agccaaggaa
   135661 aagatagtgt ggatttgatt cgggatagtt tgttttcgat tcaagtccaa caaccttggt
   135721 tactactgca atttgatgat tccaacatag aagaaattgg tgaagaccgg gtcaacaaga
   135781 ttctatctgt gagtccagat gaaaacaaag gcaaagatcg ggaagaagcg gtcaaggcag
   135841 agattgaaga caatgacaat gcgaatctca gtattaccaa gaccatgaac cgtttaggga
   135901 ccgtggtctt tttggtattg ttcaatattg gcatttcctt ctttgttttt cttctaacag
   135961 ggattatgtt gttctcgcaa attctcttca ttatctttgc gatgtttctg ccaattagtt
   136021 tcttattgtc catgttgccg acttatgaaa gtttaggaaa gaaggcgatt attcgtttat
   136081 tcaatacgat tatgatgcga gcgggtgtta ctttggtgat tacgactgca tttagcatct
   136141 ccacgatgtt tttcaatatt tcggcaacct atccattttt catggttgct tttctgcaaa
   136201 ttgtgacctt tgccggtatc tatttcaaat tgggcgacat tatgagtatg ttcaacctcc
   136261 agagtaatga tagccagtca atgggaagac gcgtcatgcg aaaaccgcaa atgttaatga
   136321 atcgaaaatt gcggcaactc aatcgaaatg tgggacgagc tttggctttt ggtggtggtg
   136381 cagcagtcgg aaataagttg gcaaaggaac aatcaaaatc caaatttaag ccatccggtt
   136441 cttctctacg aaagaattca cgattaccga acgatcacga aatactatct gacttaacta
   136501 aggagaatcc agtttcaaat aataagaaac aatcccgaat gaatttggct gggagaaaaa
   136561 tcggcaaagt tttggatacc caagctttgg tgaaagataa gactaaacaa gtaaaggatc
   136621 aggtaaggaa tacgccaacg aatttgaaat acaatctcca taaaggaatc gaaaagtcga
   136681 aaaaagcacc agaagaattc aagcgcggac tgttccaaga aaaagcggat cgagtggatt
   136741 tgcgagaaaa acaacgacaa cgaagaaatg cgaaaatgga cgaaaaacgc aagatactga
   136801 gtgaagcaac aaatcgtcag ggaaaaagaa gggcgaatat tccaatagat aaagcagctc
   136861 aacctcagaa agatatgatg ctgaaaaaag aagcaccaaa gcggattgtg agagcaaatc
   136921 tgaatcccga aatcaaacga aaactaacta gtcaagaaat catttcaaaa gggaaaagcc
   136981 aatcagcaag taagaaaaat tctttccaac aagtgaaaca gaggtccact ctgccaaagc
   137041 agaccaatca aaaagtacaa aaaagaatga accatcgtcc aaaatcaagg tcaggtgaga
   137101 aaaaatgaac ttgaagaaag tgggtgttat ttcattaact tttctgacca tctcttttat
   137161 gggtattttg atgtgtgtgg gtttgttgtt tggtgaagac agtgagggaa atggtagttc
   137221 tggcacttct cctggcggaa ctagtgtctc agaagaagta ttgaaacacc gtgcaatggt
   137281 ggaaaagtat gccaaagaat cggatataac agagtatatt ccaattcttt tggcgattat
   137341 tcaagtggaa tctggtggca caatggaaga cgttatgcaa agttctgagt cagccggatt
   137401 accacctaat tcattaagta ccgaggcatc catcaaacaa ggctgtctct attttgcgtc
   137461 tttggttaag cgttccaaag aactagggtg tgatcaagat agtattattc aggcctataa
   137521 ctatggtggc gggtatctag atcatgtcgg gaaaaacggg aagaagcata gttttgcttt
   137581 agctgaatct ttttcaaagg aaaaatcagg tggtcaaaaa gtcgattacc ccaacccaat
   137641 cgcgattaag gaaaatggtg ggtggcggta taattatggc aatatgtttt actgtttatt
   137701 agtgaagcaa tacctaacta caactcagtt tgatgacaaa atagtccaag aaatttttga
   137761 tgaggcattt aagtatgaag gaacggccta tgtgtttggt ggctcaagtc cagaaacggg
   137821 gtttgattgt agtggcttga cccaatggtg ttatgccaaa gttgacctga aacttcctcg
   137881 ggtggctcag gatcaatatg atgccatgac tcatattgat ctaaaagatg ccaaaccagg
   137941 tgatttagtt ttctttcatt caacctatga tgccggtact tatgtgaccc atgtgggcat
   138001 ttacgcaggg gagaatcgca tgtttcatgc aggagatcca gtggggtgga cgaatctaac
   138061 ggaaaactat tggcggcagc atcttatcgg agctggccga tacaaataag agaaaagagg
   138121 aaaaagaatg aagataaaaa ttgaacggaa tcaaaaggaa aagagcccaa aaaagaaaaa
   138181 agaacgagtt gtatccgtgg gtaagcatcg aaaaatggtg cttgcccttt ggcttttatt
   138241 gtcttgtagt cttgcttttg gcgtttataa aaatttcacc gccattgatc aacatacaac
   138301 tcatgaaaaa gtggttataa aagagaaggt agtgaatact tctggcgttg aaagttttac
   138361 agaggatttt gcgaaagaat atttttcatg gaaaaataac aaagaagcaa ttgaaaagag
   138421 aatgagtaat ctcgaacagt accttacaga aaacggtctc gctttaatcc aagatatggt
   138481 tcgagcagat attcccacga gttccgaagt tcaatctgta aaaattctag atgttgaaaa
   138541 acactcggaa gaatttgtcg tttcattttt agtggagcaa catattacag agggaaaaaa
   138601 gacgcaatca atttcttctg catatcgagt gacaatcttt gaagatgaaa acaggaatca
   138661 tttagtaact agtttgccaa caatgattgg aaagccagac aaggcaaaat atgaagcaaa
   138721 acaagtagaa aacgattcag aaattgatgc caaaacaacg gaagaaatca ccgatttttt
   138781 agaaacattt tttaaacttt atccatcagc ttctgaaaaa gaattggagt attatgttga
   138841 aaatggtgcg atgcgaccaa tcaatattga cttaaagttt tcggagttag agaatccagt
   138901 ttatctacaa aacggaaaaa attttctagt gagtacaaag ataaaatacc ttgataatgt
   138961 atcaaaaacc actagctact ttcagtacaa attagtatta caaaaaaatg gaaactggaa
   139021 aatcgttgat gttaaataat aatgactcaa tctaatttta ttagaagtta taagtagtgt
   139081 aacttatttc aggcagaagt cgcccatcct ctataggtgg gtgatgaatg ccattcggta
   139141 actcgaaaac cgacaattaa gacatagtgc ctttttattt taatccatgt cataatcagt
   139201 ctatatagga aatggttgat ataccatgga attagataca aataatcatt cagtttttct
   139261 tcttggttac ccccttattt tagtagtgaa acattgtaaa catgtcattg atgatgtaat
   139321 gtcagcttat gcaaaaactg cctttgaaag aatttcagaa tcacatcaca ttaccttaga
   139381 tgaatgaaat cgtgataaag aatactttca tattatgctc aaagcacaac ctaaaaccga
   139441 attaacaaaa ttcagcaatg cctaagctca cgtctgataa aatgagactt tctaagggtc
   139501 aaaaatttcc tttgaatacg attattgctt agataaaagt aaaagcctta gaactacggg
   139561 gatagcttgg ttaataagag atatcgttgt tagtaaagac ataggcttgc aagtatgctc
   139621 tattcccaag aatctccccc ttcaagcacc aaggatcgtt aaattcagct aagtggcaag
   139681 taattcacta gacgataatt atctccatat ttcaatctca gcttttccat ttttcatagc
   139741 aaattccgtt atttttatag catctaaaag attcagcttt tccactgatc tttcaccact
   139801 tttcagcttt tttattgtgc ttaaattgat accagtacct tttgatattg aattggaagt
   139861 aaaatcatta agggtttttt ttattaaatt catatccgca attccagcgt tcataagaat
   139921 gaagattctc ctctcataga ctactttgaa aatggtacta cagtggctgt ttatatattt
   139981 cagtaggtta ctgtagtggt catcttatta taattagaaa aggaacctaa atcaaaaatg
   140041 ctaaagaaaa ttttcatagt attaagcctc tcatgactaa agccacggaa ttcttgataa
   140101 aagagtatac ttgcaagcct aaacagcggt atctcttatt aaccaagcta tccccgttgt
   140161 tcctaaggtt cttgatgttt tctaaggcaa tgcttgtatt catagccctt ggtcaaaata
   140221 ttgatactat cgttgacgtt tcgattatga tgtatacggc aaataggaca agtccattct
   140281 cgaattgtga gtgacttctt accatctgtg tgtctacatt ctgaaccaat ttgactagac
   140341 ggaaatcatt tatctatctt aatgattttt tgacagaagt atcgaaaatc tttacataat
   140401 ctgggtgatg tattcttatg cagatgagag cgttggctcc gtattcataa ccagtagcct
   140461 ctaaaacgta gtccatcggt gggataccta gcttgcggtt gccagcggct ttcgcagtct
   140521 tcttgtgatc aaatcaagca tctcattgag cactagtatt ttgaagataa tacttgagtt
   140581 tttcggcttt tagaagttca cttcatcttc catcatccat ggaaatccca ctcacccata
   140641 cgcaggcctc caaaaattct tcaacagtgg ttttttcaga catttttctg aatacctcct
   140701 tgttttttga tacgccagat agtcaggaaa aaggcaacaa aacacaaaac aaagctgcct
   140761 aaaaaggtaa tcttcattcc atataaaaag acatccggcc gatttgcgat atagttagtt
   140821 acttgctggc ccatcttagc agacatcgct tgatataaga ccgtcgtaga aagcgaaatc
   140881 ccgctgacca tccccaaatt tcgggcaaag gaattcatcg agcctgccag tcccaagttt
   140941 tcgatagtga ccgagctcat aaccatcgta ttattggggg actggaacaa ggcattgccg
   141001 gcacccatga tggcagtagc gacaatgtat agccacaaag gagagtccac tgacaaaaac
   141061 atatacatga cctgggttac cgacaataag cccaagccta ctaataccaa aatctccggg
   141121 ccaacccggt cggtcaggta gccgcttaaa ggcgccccga cgaccatcat caaaggaaag
   141181 accatcatca acagcccagc atagctagga ctcaacccgc gagcattttg cagataaaaa
   141241 ggaatcacta cattgacaaa gaagttggaa gaaaaaatca acaaggctgt aatcaagctc
   141301 atggtaaaaa tcttgttctt aaaaataccg aaagaaatca atggagaggc tgctttcttt
   141361 tcaactttta aaaagctgac aaaggcaatc actgaaatta cgaacagtac aagggggact
   141421 ggatggaaaa agccactttc ttgccccaaa aagattgctc caaaaaagct gataatcgta
   141481 gccgcaatgg cagcaaagcc ccctccatcg attgtatggc cgctcatggt gatatctttt
   141541 ggtaagaatt tttcagcaat caacatcgtt acgattccca ccggtacatt gatccaaaaa
   141601 atgtacgccc aagaaaattg ggacaaaatc aagccgccaa gacctggtcc agcaatcgag
   141661 cctaatgaaa caaacgcacc tattgctccc aatgcccgac cacgttcatg tatgggaaag
   141721 acttccgtga tgattccggc atttgtagcc atagtcatac tagcaccaat ggcttgtacc
   141781 acccgtgcga acaataaaat acctagcgaa tgattgaacc cacacaacag cgatcccaag
   141841 acaaagatca gcgtaccaat ccgaaatact ttgattttcc cacggctatc gccaatttta
   141901 ccaaacagca acaaacaaga acagacaatc atcagataaa cggacactac ccattccgct
   141961 tgattcattg gtatgcccat atcatctgag atggtaggta gtgcaatatt gacaatactg
   142021 ccatccaatg tggacatgaa ggtaaacata gatatagcaa tcaaaatcca ccagcgattt
   142081 ttttggactt ttgcatcttc ttgataacta tacataatag gatttccttt ctaatgatcg
   142141 tgtagctaag aacaatataa cctatgtcta ctgcccaaca acttctcgcg actctagcca
   142201 taggaagctt gagtaatttc gatttgatat cctcatgtaa ccatgtaagt tggagatgct
   142261 ttatttgaac ttactctata gtaactagtg ataattcgct ttactttctt ctagcaattt
   142321 ctaaaagtcg acttcattgt tcttcagatt aatagtgtga gctatctcgt gagacgtaag
   142381 caaatttcca ttctactttt tcccaatttt ttcatattta tggtgttgca cctatttgtt
   142441 ttccaatttg cttttcaaat acattgctat gatattcaat tccataggat tatactaaat
   142501 atcaatagta tgaataatat attatagatg tttatatatc actgttaatt attatccaca
   142561 ataattaatg attacctcga tatttgtcaa tcaaaggttg aaacaattta ttttcagcat
   142621 cttttctagc ttgagctgca ctcttaatag aatcatacga tcctaaatag tacctctttt
   142681 tttttaaagt tatatacgca atctatttct ctttagaacg ataaactccc ttaacaccac
   142741 ttgtattatt tttcggtaat tttgacgtta gacactctat tactgtccct tcaacacatg
   142801 tccttgtttc ttgccttttt aaacatccac aactttgagt atgtccaaaa aataagttac
   142861 tataacttat ctcacacata ctgccacact cacaatgaca aacccatttt gttttccatg
   142921 aacagttatt gtccaaagga tactttgcag taagtaatcc gaatttttta ttttcaatgt
   142981 gatgcttttt tgatttcaaa catccacagc tttttacatc accttttaga agtcgctttg
   143041 ccgatactaa cttttttctc ccacacagac attgacattc ccaaacaaca gttccttcac
   143101 ttcgcagttt agttggcttg attgcaacta acttaccaaa agttttattt gtcaaatttt
   143161 tatatttatg cctattttta taatttccac atccacaact tttggttcta cctgatagta
   143221 agtttgatcg atatacaatc gtttcattcc cacagtcaca taggcaacga tattttttat
   143281 atccattatg agtaatctcc tcaacaacag taaggtgacc atatctttcc ttcactgcac
   143341 ctaccctccc aagaaagaag taccatataa tttcaattaa cttttaataa atcagaaaaa
   143401 aatatttcca atttttctta gtctgatttt atgactaatt tacaatacaa gactgaacga
   143461 tacgtacacg aaatcctcaa gatagataaa ttgttttcat ctagtgaaac ctgctcaaaa
   143521 tatgagcata aagacggcaa taatacactc gatattcgat aatggacttg ttttatttgt
   143581 caaacccatc gtaatcgaga tatcaattcc agtctcaata tcctgatcaa aggtctaaga
   143641 atccaaccat tttcttgtta ctttgtcaga ttgattacct tttttagtct ccgaataata
   143701 aggttttcgg atcaactaac atgctctgag aaagactact atctttgcaa atttccaaat
   143761 gaaggtgtgg gccagtacta ttcccagtac ttcctacata gccaattatt tgtccttgca
   143821 aaacattatc tccagttttt actaggtatt gttgctggtg agcatataac gcggttgatc
   143881 catcttcgtg ttgtatcacc acgtaatttc cccaagagta gtgaaactct gctttaacaa
   143941 ccttaccagc tttaactgca tgaatcggct caccctgtgt agctgccata tcaagtcctc
   144001 ggtgaaattc atttccacga tttccaaaca aactggttat tgaataatta tgaataggca
   144061 cttggtatcc agtcttactc atttgtggac ctttaacttc tttatcatag ttggttaaat
   144121 cgtaggtttt aattaattca tttagcttca aatagtattg tgtatctgtt gcataccgtc
   144181 ctgtaaggaa tttagttgct tctcgatatg ttttactatt agcttttaat gctcctgcat
   144241 aaaaatcttt atttccacta attcccttag ttaataattt ggcataatct tcaaagcttt
   144301 cctcatagtt ttcatacact ctaaattttg attgggtcgt ataaagcgtt ccattaccca
   144361 aatcttcgtt tgttaccata atgacaaagt ttccattata agttcctttt atcccaaata
   144421 aattgtaatt cggtgcctga gctaactggc tttgaccact ggcagattct aagatcgctt
   144481 gtgcaatcat aacagaagca tataaatcat atttctgacc aatttttctc gcagactcac
   144541 caattttcat aataaaattt tctacagatt catttttgtc aaaatgaatt tcttcattac
   144601 cagatagtat tggttgtgat tggaaagatt ctgttgattc tatttgctgt ggtgtcgaaa
   144661 aagtttttgt ttgtccttcc gtttttggcg cttccttttt tgaagattct atatggtttg
   144721 gttttgtcac tttcgaagaa gttatttcac ttgtactact tgaagttgtt gaagattcgg
   144781 tacttgaaat cgtactactt tcacttgacg aagttgttga agactcggca tttgaagtcg
   144841 tactactttc acttgatgaa gttgttgaag actcggcatt tgaagtcgta ctactttcac
   144901 ttgatgaagt tgttgaagac tcggcatttg aagtcgtact actttcactt gatgaagttg
   144961 tcaaaagttc actactctct gctgttacat cggaattact catttcagtc gtctcggttc
   145021 tttcttttgc aattttgtat gttgaatttt cgcttgccaa cacatggaaa ggtgttgcta
   145081 taaggagttg ggacattaat ataactgctg atgcaagttt taaagatttt ttcatttgat
   145141 ttacctctct tttttctctt taatagtgtt ttctattaaa aattatgata aatattttca
   145201 atgaattgag taatacagta tatttcttga tttcatttag taacgattat gtttcaatgt
   145261 ttaatcctgt tactgccttt aaaataaaat tatagggttg gctaaaacta ggatgaaata
   145321 aataatctaa cattttcaat ttgtctaatg taatttgttc ttctatagca agagaaaaca
   145381 ttgataatag tccagataaa tcttcttgac tacaaagttg tacacctact attctctttg
   145441 tatttttttc aaagctaatt cttaatttta cacgactatt ttttctcaaa aaagcaggtc
   145501 taatgaaatc ttctatttct atataatcta tagactcact taataatcgt gctgttttta
   145561 aattcaaacc tgctgcgtaa aaattgtaat taaatataga aaagccattt gtaaattggg
   145621 aaccagaagg tgtaaaatct tgattgttaa tatgttgagt tgcaatataa gctgttctta
   145681 gagcattaga aatagaaaaa tcaacactac ttctattaat ggacgtaaaa aaagttgtag
   145741 cacaatcccc aatagcatat atatctttta tatttgtttg ctggtattca ttagttagat
   145801 atgctccact aacatctctc aagagttcct tttccccaat tggactatta gatagaaatc
   145861 ctatagcttg tacgaccata tccatagagt attgggtacc acttgtagtg actatttttt
   145921 caatcttttt tcttcctaaa tattttttag gactttctga tagacaaaga tgtattccat
   145981 tttttgatag tatttcttca actttatctg aaaaactacg gtcgtaataa gtcgacaaca
   146041 ctctatctgc aacatcgaaa agatatactt ctttccctct ttttcttatg gcttcagcaa
   146101 tttcaactcc aatatatcct gctccaataa ttcctacttt tttaatagta ctatcatcca
   146161 aagctttaaa aatctctttt gcatttggaa aattctttat cgaaaaaata ttagctaaat
   146221 tattccccgg tatatctagc ataatttgct ttgaacctgt agctaatata actttgtcat
   146281 attcttgaga gaatcttgta ccatcttttt ttacacaact aatcttttta ttttgaatat
   146341 caattttgtc aacttctgtc tctagaaata acttttttat ctcagaattt agtgtcattc
   146401 tattttgata aaaaagatct tctaaattac ttacttctcc ttttataaat aacgatgtcc
   146461 cacattccaa gtaactaatt tctgattttt tatcgattag aataacttca taatttgaat
   146521 cgcttaagtt tagaaatcga gctgcggcta gccctgaatg gtttgaacca ataattacta
   146581 ttttttccac ttaattacat tcttttcctt tctataaaaa gtatattcat ctttaactaa
   146641 cacttatttc ccatcataaa aaagcaaaaa gaggaagaaa aagattcttc ctcttctcag
   146701 agaagactta agaaattgat tttctattca ttctcttttt ttcgattttt ataccctaat
   146761 aatcctaacg ttcctaacag tattaaacca ccgctaatag taaagatatt actgtcactc
   146821 tctcccgtct taggaaaaac ttttgaggac tggcttttgc ctctattttt gtcttgattg
   146881 ctgttgctac cttgattgtc agtcttacta cctttactac cgttttttcc actgtctttt
   146941 ttgttggaag aaacaactac attagtaggt tcactagtat taccagattc atcagttgca
   147001 gttactatca cttttgtccc tgcctctaat ttaggaactt taactgtaaa attaccattt
   147061 ttatcagctg tcccatggtg ttgacttccg tctggtaatg taactgtcac ctctgcattt
   147121 ggttcagttt taccagtaac aatttggtca ccctctgtaa taggatcaac ttgaggttta
   147181 ttcggtgctt ttttatctac tacagaaata gtaacttcta cttcttcttt agatccatct
   147241 ggatatgtta ctactacagt accttttttg tttccagctg tactaacatc tactttttct
   147301 ttccaagtat aagtagttcc ttttggtaga tcttctttgt tcttaattcc ctcagatgca
   147361 tctggctctt tatttaagtc tgtagtcact ttttgtcctt caggattata tttatctgca
   147421 tcggaacgag tatctgtcac tgtaacgtct acttcaactt catcagatga tccatctgga
   147481 tatgtcacta caatagtacc ttttttattt ccagctgtgc taacatctac tttctctttc
   147541 caagcataag tagttccttt tggtaaatct tctttgttct taattccctc agatgcatct
   147601 ggctctttat ttaagtctgt agtcactttt tgtccttcag gattgtattt atctgcatta
   147661 gaacgattgt ctgtcacttc tactggaact ttcaccgtat ctttcgtacc gtctggatac
   147721 gttacttcaa tgacaccttc ataattgcct ggtgtgttgg tatcaattgt accgccggga
   147781 gtaacatctg ttactgttgt tccttctggt aacgctggca agttagtaac attatctgtt
   147841 aaatctactg tgcctccaat ttctactttt tcgccttcta ctgttggttc atatttatcg
   147901 gcgtcagaac gattgtctgt cacttctact ggaactttca ccgtatcttt cgtaccgtct
   147961 ggatacgtta cttcaatgac accttcgtaa ttacctggtg tgttggtatc aattgtaccg
   148021 ccgggagtaa catctgttac tgttgttcct tctggtaacg ctggcaagtt agt
//
LOCUS       DADLIO010000002       120812 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.002, whole genome shotgun sequence.
ACCESSION   DADLIO010000002 DADLIO010000000
VERSION     DADLIO010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 120812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 120812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..120812
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.002"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(33..1184)
                     /locus_tag="JOX41_000136"
     CDS             complement(33..1184)
                     /locus_tag="JOX41_000136"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HAY6447911.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(1197..1634)
                     /locus_tag="JOX41_000137"
     CDS             complement(1197..1634)
                     /locus_tag="JOX41_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAY6447912.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGGVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            complement(1649..3415)
                     /locus_tag="JOX41_000138"
     CDS             complement(1649..3415)
                     /locus_tag="JOX41_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HAY6447913.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEALATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            3679..4356
                     /locus_tag="JOX41_000139"
     CDS             3679..4356
                     /locus_tag="JOX41_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6447914.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            4359..5486
                     /locus_tag="JOX41_000140"
     CDS             4359..5486
                     /locus_tag="JOX41_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAY6447915.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLPLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(5686..6126)
                     /locus_tag="JOX41_000141"
     CDS             complement(5686..6126)
                     /locus_tag="JOX41_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAY6447916.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAKTIEEVQMIFEHGHI"
     gene            complement(6137..8170)
                     /locus_tag="JOX41_000142"
     CDS             complement(6137..8170)
                     /locus_tag="JOX41_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAY6447917.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            complement(8172..9875)
                     /locus_tag="JOX41_000143"
     CDS             complement(8172..9875)
                     /locus_tag="JOX41_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAY6447918.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKKSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            complement(9969..10919)
                     /gene="manA"
                     /locus_tag="JOX41_000144"
     CDS             complement(9969..10919)
                     /gene="manA"
                     /locus_tag="JOX41_000144"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HAY6447919.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIATEPGK"
     gene            complement(10958..11983)
                     /locus_tag="JOX41_000145"
     CDS             complement(10958..11983)
                     /locus_tag="JOX41_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HAY6447920.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKTVLPK"
     gene            complement(12192..13061)
                     /locus_tag="JOX41_000146"
     CDS             complement(12192..13061)
                     /locus_tag="JOX41_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HAY6447921.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            complement(13520..15412)
                     /locus_tag="JOX41_000147"
     CDS             complement(13520..15412)
                     /locus_tag="JOX41_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6447922.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(15409..17136)
                     /locus_tag="JOX41_000148"
     CDS             complement(15409..17136)
                     /locus_tag="JOX41_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6447923.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(17152..17802)
                     /locus_tag="JOX41_000149"
     CDS             complement(17152..17802)
                     /locus_tag="JOX41_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAY6447924.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            18006..18302
                     /locus_tag="JOX41_000150"
     CDS             18006..18302
                     /locus_tag="JOX41_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAY6447925.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            18474..19094
                     /locus_tag="JOX41_000151"
     CDS             18474..19094
                     /locus_tag="JOX41_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HAY6447926.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(19186..20352)
                     /locus_tag="JOX41_000152"
     CDS             complement(19186..20352)
                     /locus_tag="JOX41_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAY6447927.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(20364..20717)
                     /locus_tag="JOX41_000153"
     CDS             complement(20364..20717)
                     /locus_tag="JOX41_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HAY6447928.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLETVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            20845..21867
                     /locus_tag="JOX41_000154"
     CDS             20845..21867
                     /locus_tag="JOX41_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HAY6447929.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            complement(22306..22740)
                     /locus_tag="JOX41_000155"
     CDS             complement(22306..22740)
                     /locus_tag="JOX41_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6447930.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLKKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(22850..24709)
                     /locus_tag="JOX41_000156"
     CDS             complement(22850..24709)
                     /locus_tag="JOX41_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAY6447931.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(24827..25987)
                     /locus_tag="JOX41_000157"
     CDS             complement(24827..25987)
                     /locus_tag="JOX41_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HAY6447932.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(26294..27718)
                     /gene="araA"
                     /locus_tag="JOX41_000158"
     CDS             complement(26294..27718)
                     /gene="araA"
                     /locus_tag="JOX41_000158"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HAY6447933.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(27734..28432)
                     /locus_tag="JOX41_000159"
     CDS             complement(27734..28432)
                     /locus_tag="JOX41_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAY6447934.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(28389..30050)
                     /locus_tag="JOX41_000160"
     CDS             complement(28389..30050)
                     /locus_tag="JOX41_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HAY6447935.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKR
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            30268..31668
                     /locus_tag="JOX41_000161"
     CDS             30268..31668
                     /locus_tag="JOX41_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HAY6447936.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKVLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIIGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(31920..32999)
                     /locus_tag="JOX41_000162"
     CDS             complement(31920..32999)
                     /locus_tag="JOX41_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAY6447937.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(33085..34044)
                     /locus_tag="JOX41_000163"
     CDS             complement(33085..34044)
                     /locus_tag="JOX41_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HAY6447938.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(34056..35579)
                     /locus_tag="JOX41_000164"
     CDS             complement(34056..35579)
                     /locus_tag="JOX41_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HAY6447939.1"
                     /translation="MDEEVKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHE
                     TADGDGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIE
                     PNSFGLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQ
                     KKPFGVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPR
                     LPSYPEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFD
                     RQIEEIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMED
                     TLLFGSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAK
                     GQVLKQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLL
                     DQGEHYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(35589..36152)
                     /locus_tag="JOX41_000165"
     CDS             complement(35589..36152)
                     /locus_tag="JOX41_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HAY6447940.1"
                     /translation="MKIVETKFYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(36158..37021)
                     /locus_tag="JOX41_000166"
     CDS             complement(36158..37021)
                     /locus_tag="JOX41_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAY6447941.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(37035..37931)
                     /locus_tag="JOX41_000167"
     CDS             complement(37035..37931)
                     /locus_tag="JOX41_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAY6447942.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(38106..39377)
                     /locus_tag="JOX41_000168"
     CDS             complement(38106..39377)
                     /locus_tag="JOX41_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAY6447943.1"
                     /translation="MKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTLTFWNGF
                     TASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFIALNYPD
                     FAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMYMYWNND
                     LFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLANGGKLV
                     NDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIEINGPWL
                     NNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFLKYWNTT
                     EIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQISAINNDI
                     INPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(39367..40884)
                     /locus_tag="JOX41_000169"
     CDS             complement(39367..40884)
                     /locus_tag="JOX41_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HAY6447944.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            41082..41972
                     /locus_tag="JOX41_000170"
     CDS             41082..41972
                     /locus_tag="JOX41_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HAY6447945.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(42045..42869)
                     /gene="nadE"
                     /locus_tag="JOX41_000171"
     CDS             complement(42045..42869)
                     /gene="nadE"
                     /locus_tag="JOX41_000171"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HAY6447946.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(42881..44353)
                     /locus_tag="JOX41_000172"
     CDS             complement(42881..44353)
                     /locus_tag="JOX41_000172"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HAY6447947.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(44990..45352)
                     /locus_tag="JOX41_000173"
     CDS             complement(44990..45352)
                     /locus_tag="JOX41_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HAY6447948.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            45575..46327
                     /locus_tag="JOX41_000174"
     CDS             45575..46327
                     /locus_tag="JOX41_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAY6447949.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWLSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(46467..47390)
                     /locus_tag="JOX41_000175"
     CDS             complement(46467..47390)
                     /locus_tag="JOX41_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAY6447950.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYQKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(47405..47677)
                     /locus_tag="JOX41_000176"
     CDS             complement(47405..47677)
                     /locus_tag="JOX41_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6447951.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
     gene            complement(48147..49772)
                     /gene="groL"
                     /locus_tag="JOX41_000177"
     CDS             complement(48147..49772)
                     /gene="groL"
                     /locus_tag="JOX41_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HAY6447952.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDATIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
     gene            complement(49823..50107)
                     /locus_tag="JOX41_000178"
     CDS             complement(49823..50107)
                     /locus_tag="JOX41_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HAY6447953.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            50332..50994
                     /locus_tag="JOX41_000179"
     CDS             50332..50994
                     /locus_tag="JOX41_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAY6447954.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            complement(51070..52362)
                     /locus_tag="JOX41_000180"
     CDS             complement(51070..52362)
                     /locus_tag="JOX41_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAY6447955.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQHLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            52532..53161
                     /locus_tag="JOX41_000181"
     CDS             52532..53161
                     /locus_tag="JOX41_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HAY6447956.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAASDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            complement(53264..54073)
                     /locus_tag="JOX41_000182"
     CDS             complement(53264..54073)
                     /locus_tag="JOX41_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAY6447957.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(54128..54997)
                     /locus_tag="JOX41_000183"
     CDS             complement(54128..54997)
                     /locus_tag="JOX41_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6447958.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            complement(54998..56314)
                     /locus_tag="JOX41_000184"
     CDS             complement(54998..56314)
                     /locus_tag="JOX41_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6447959.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            complement(56311..58146)
                     /gene="walK"
                     /locus_tag="JOX41_000185"
     CDS             complement(56311..58146)
                     /gene="walK"
                     /locus_tag="JOX41_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HAY6447960.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVILSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            complement(58151..58855)
                     /locus_tag="JOX41_000186"
     CDS             complement(58151..58855)
                     /locus_tag="JOX41_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAY6447961.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            complement(59045..59905)
                     /locus_tag="JOX41_000187"
     CDS             complement(59045..59905)
                     /locus_tag="JOX41_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAY6447962.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITPEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            complement(59892..60461)
                     /locus_tag="JOX41_000188"
     CDS             complement(59892..60461)
                     /locus_tag="JOX41_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HAY6447963.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            60842..60914
                     /locus_tag="JOX41_000189"
     tRNA            60842..60914
                     /locus_tag="JOX41_000189"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:60875..60877,aa:Lys,seq:ctt)
     gene            complement(61410..61796)
                     /locus_tag="JOX41_000190"
     CDS             complement(61410..61796)
                     /locus_tag="JOX41_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HAY6447964.1"
                     /translation="MNKRKTEFILILISGITGILCSLLALMGGMFLSSIDSTTLNTTE
                     LTSKDIDMLVNLSGNVVLFGGITLVFSIMIFIIGFLVRKNQKTVVYGISLLILSIIPF
                     FLLTLLWVIPGVLGIIAGLMLLIRKS"
     gene            complement(61793..62314)
                     /locus_tag="JOX41_000191"
     CDS             complement(61793..62314)
                     /locus_tag="JOX41_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HAY6447965.1"
                     /translation="MNKKSGIETLPNYVFAGFWLRFFAFLIDLICISIITHATIGLFY
                     KIMGLESDKSIITFYGIASLAIYLTYFVLLTKLNSGQTIGKMIFGIRVVSFEEKELSW
                     QTIFIRECICRFILKNFVFQIGYLVAAFTPKKQHIGDYFSNTSVVVIRSLEAINYGQK
                     ISNSKTLNLERIK"
     gene            complement(62316..63350)
                     /gene="sppA"
                     /locus_tag="JOX41_000192"
     CDS             complement(62316..63350)
                     /gene="sppA"
                     /locus_tag="JOX41_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HAY6447966.1"
                     /translation="MNKRRWIAVGVACGLLLLSIIVALIPGKDKEEASNTTLTGINKI
                     FYGSNEITEETLEEGASNKKIVKLSVNGVIADTGESNLFSREQYNHQNFLTQLKKIQE
                     DKAVKGVLLEVNSPGGGIYESAEIAKEMAKIKKLDIPIYTAFKNTAASGGYYISAGSD
                     KIFATEETTTGSIGVIISGLNYSGLLEKLGVTDATYKSGALKDMMSPQHKPSEEENKV
                     IQEFVMSAYDRFVNVVAKGRNMDTNAVKELADGRIYDGNQAVENGLVDQIGYSEDALD
                     SLKKEKKLTDATVIEYKNDTTGFASSWLGNKIAEWQGLKATTSDRVISVFEKLGFSDT
                     PKPMYYYGGL"
     gene            complement(63383..64798)
                     /locus_tag="JOX41_000193"
     CDS             complement(63383..64798)
                     /locus_tag="JOX41_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HAY6447967.1"
                     /translation="MVSIKNYGKSRRGKQFMQNNNWFEHSSIYTKQHHSFYRWVLYPV
                     ILFLCIIGLFLTFAKKEVVIRTTAQLNPEKIEKLQVPLEAKIMENFLKENQFVHKDDV
                     LVRLDCSLIENEKAQIEQENQRITQQIKMAQLFIESISKGKNLFSTDDSFGYSNQLKS
                     MLSEKESLRYALKQSELNDQKQLEVYEKTKRQLEKQIESSDSKLQEWQQVQVAWSNNQ
                     SLKDFSKEMMANYENWQEQLNNVSDDQKNQVKLTISASINEQIEQLKKEVEQYQSEKA
                     KLVKPTTSENDRISQTEKGKQELEQAITTVKQTVTELNEKQEKNQSVIKSLDDQLSKG
                     ILKAPVSGTVHLNEETKGQAELAKGTVLAEIYPIHEKSKMKFTALLPANESTYIKEGM
                     KVHFKLDQKGGAPITIDGTLDEISENSTATEKGVFYAVKGTLKTTQSFPFRYGLTGEL
                     SLIVGEKTYWQQIVDVFLNKK"
     gene            complement(64767..66920)
                     /locus_tag="JOX41_000194"
     CDS             complement(64767..66920)
                     /locus_tag="JOX41_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HAY6447968.1"
                     /translation="MIKSFPFVQQQDEKDCGVACLSMILKYFKTDIPIHKLRDLSGTD
                     LEGTSAFGLKKTFEKLSFDCMAIQADSEIWKERDLILPLIAHILVDNSYMHYVVIYKT
                     KGNVLWIADPANGKNRKTIEAFQKEWTGILLLPMPRETYIPIKEKVAGLSSFLPIIWK
                     QKGLVFHIVLASIFITFFGIGSSYYFQGILDFFIPNQARSTLNIISIGLIAVYLFRVL
                     FEYSRSYLLIILGQRMSMAIMLQYFKHVLTLPMNFFATRKSGEIISRFLDASKIIDAL
                     ASATLSIFLDIGMVLLVGVTLAIQNSTLFLITLCSLPFYVVAIFAFVKSYEKSNREEM
                     AAGAAVNSSIIESLKGIETIKAYSGEEKVYNRIDHEFVKLMKKSFRTVTLDNIQQGIK
                     HLIQLISSALILWLGSYFVMDNRISLGQLITYNALLVFLTDPLQNIINLQVKMQTAQV
                     ANNRLNEIFAIDSEKSNQSFEYMLSEQLFQQDITVKNVSFSYSMKAPTLNEISCTIPS
                     HSKTAIVGVSGSGKSTLAKLFVRFYEASEGSIHYGNINHLDIPFQILRDRVTYLPQES
                     FFFSGTIIENLIFGLDSPPSFEQIIEVCEIVQLNEFINQQPLRYETLLEEGGNNLSGG
                     QRQRLALARALLKNPDILILDEATSGLDTLLEHAIMNYLLNLKEKTIIFIAHHLPIAK
                     ACDQILVLHEGHLVEKGTHDELRFADGIYQKLWEI"
     gene            67178..67414
                     /locus_tag="JOX41_000195"
     CDS             67178..67414
                     /locus_tag="JOX41_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HAY6447969.1"
                     /translation="MFKHAKCKGTKYCGNAQTVGGGNNAWGKLGQVVGGLTTGAVGGA
                     GLGTAICGPACGVVGGLYGAVAGGAAAGWDARKK"
     gene            67433..67648
                     /locus_tag="JOX41_000196"
     CDS             67433..67648
                     /locus_tag="JOX41_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HAY6447970.1"
                     /translation="MHIKNTKTTFILSSEELKNIQGGSAVGVLGTTFSGATAGVKLCS
                     AGGPYAIAACGVGGALLGAGFSMWTGA"
     gene            complement(68351..69103)
                     /locus_tag="JOX41_000197"
     CDS             complement(68351..69103)
                     /locus_tag="JOX41_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAY6447971.1"
                     /translation="MSYPIILCEDQIIQLNQLERIIDNFILFHDKVFKIVLKTQSPLE
                     VKKYLKQFRPKQGIYFLDIDLNHEVNGIELAEVIRKYDVQAKIIFTTTHDEMLPVTIK
                     RRVETLGFVTKDQTLDEYRNEIVELLLLAQERIDATKQVTNQAFVFSIGSQTFTFDIN
                     DIYFVEASKLPHRLSLCTKDGQYEFYGRISELEKKYPMLTRISRACLVNIFNVKEIDF
                     KKRSLYFDSELARNFTLGKAQKIKEKLKESTV"
     gene            complement(69118..70365)
                     /locus_tag="JOX41_000198"
     CDS             complement(69118..70365)
                     /locus_tag="JOX41_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAY6447972.1"
                     /translation="MFVGNFFFFLLFYMTNTDLNKRKYLFVCLLIPLTFFVELFTDVS
                     AAIPIIGSYFILKEKKKTNIVLLNKLLLCMLIDDFRSIITSMVMTYMFSFEGIKGYGY
                     VVFQIMLDSLFLLMFIWLYRKLAINRIVEQSSSKLTAIFMIYLLTIGLFVSYVAHQYQ
                     VFDHFVFGVLIFLIIQMFVVLFLFIRITIRQREQYEQQLKRKELVYLKKYTDSLEKDQ
                     EKFARFRHDYKNLLLSLKEIANQNHDSILEKEIKELEIYSNSYLTNKFEYRYLKNIKN
                     EYLKSLLIAKLYQANNNKICCKFECPSTIIEVPVPIFDCIRVLGIILDNAIEASIESQ
                     DRELSLAIYRDDKQIEISISNSCREILLSIDTLMKKGITTKKGHQGLGLSSIEEINKK
                     NPNMFVNYQNDPYQFTTQVILLF"
     gene            complement(70441..70587)
                     /locus_tag="JOX41_000199"
     CDS             complement(70441..70587)
                     /locus_tag="JOX41_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HAY6447973.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFSLF
                     KKCN"
     gene            complement(70691..71002)
                     /locus_tag="JOX41_000200"
     CDS             complement(70691..71002)
                     /locus_tag="JOX41_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAY6447974.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPGPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(71004..71201)
                     /locus_tag="JOX41_000201"
     CDS             complement(71004..71201)
                     /locus_tag="JOX41_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterocin"
                     /protein_id="HAY6447975.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(71595..73322)
                     /locus_tag="JOX41_000202"
     CDS             complement(71595..73322)
                     /locus_tag="JOX41_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAY6447976.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(73315..74508)
                     /locus_tag="JOX41_000203"
     CDS             complement(73315..74508)
                     /locus_tag="JOX41_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HAY6447977.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(74695..75339)
                     /locus_tag="JOX41_000204"
     CDS             complement(74695..75339)
                     /locus_tag="JOX41_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAY6447978.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(75433..75567)
                     /locus_tag="JOX41_000205"
     CDS             complement(75433..75567)
                     /locus_tag="JOX41_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HAY6447979.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(75569..77701)
                     /gene="feoB"
                     /locus_tag="JOX41_000206"
     CDS             complement(75569..77701)
                     /gene="feoB"
                     /locus_tag="JOX41_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HAY6447980.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(77698..78171)
                     /locus_tag="JOX41_000207"
     CDS             complement(77698..78171)
                     /locus_tag="JOX41_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HAY6447981.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            78572..78796
                     /gene="nrdH"
                     /locus_tag="JOX41_000208"
     CDS             78572..78796
                     /gene="nrdH"
                     /locus_tag="JOX41_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HAY6447982.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            78955..81114
                     /gene="nrdE"
                     /locus_tag="JOX41_000209"
     CDS             78955..81114
                     /gene="nrdE"
                     /locus_tag="JOX41_000209"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HAY6447983.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFLSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYAMAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            81164..82129
                     /gene="nrdF"
                     /locus_tag="JOX41_000210"
     CDS             81164..82129
                     /gene="nrdF"
                     /locus_tag="JOX41_000210"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HAY6447984.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(82218..83357)
                     /locus_tag="JOX41_000211"
     CDS             complement(82218..83357)
                     /locus_tag="JOX41_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAY6447985.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAV
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(83666..84379)
                     /locus_tag="JOX41_000212"
     CDS             complement(83666..84379)
                     /locus_tag="JOX41_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HAY6447986.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(84633..85334)
                     /gene="nagB"
                     /locus_tag="JOX41_000213"
     CDS             complement(84633..85334)
                     /gene="nagB"
                     /locus_tag="JOX41_000213"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HAY6447987.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            85568..87100
                     /locus_tag="JOX41_000214"
     CDS             85568..87100
                     /locus_tag="JOX41_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAY6447988.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(87291..88493)
                     /locus_tag="JOX41_000215"
     CDS             complement(87291..88493)
                     /locus_tag="JOX41_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAY6447989.1"
                     /translation="MKSNEKKPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMAALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTVFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQTVVFKG
                     KRNLENKK"
     gene            complement(88575..89264)
                     /locus_tag="JOX41_000216"
     CDS             complement(88575..89264)
                     /locus_tag="JOX41_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAY6447990.1"
                     /translation="MKKKIIRLILISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(89370..89738)
                     /gene="rplL"
                     /locus_tag="JOX41_000217"
     CDS             complement(89370..89738)
                     /gene="rplL"
                     /locus_tag="JOX41_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HAY6447991.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(89791..90294)
                     /locus_tag="JOX41_000218"
     CDS             complement(89791..90294)
                     /locus_tag="JOX41_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HAY6447992.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     gene            complement(90704..91393)
                     /gene="rplA"
                     /locus_tag="JOX41_000219"
     CDS             complement(90704..91393)
                     /gene="rplA"
                     /locus_tag="JOX41_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HAY6447993.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(91497..91919)
                     /gene="rplK"
                     /locus_tag="JOX41_000220"
     CDS             complement(91497..91919)
                     /gene="rplK"
                     /locus_tag="JOX41_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HAY6447994.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            92262..92930
                     /gene="sdaAB"
                     /locus_tag="JOX41_000221"
     CDS             92262..92930
                     /gene="sdaAB"
                     /locus_tag="JOX41_000221"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit beta"
                     /protein_id="HAY6447995.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            92943..93815
                     /gene="sdaAA"
                     /locus_tag="JOX41_000222"
     CDS             92943..93815
                     /gene="sdaAA"
                     /locus_tag="JOX41_000222"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HAY6447996.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(93906..94925)
                     /locus_tag="JOX41_000223"
     CDS             complement(93906..94925)
                     /locus_tag="JOX41_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HAY6447997.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKY
                     TKLMD"
     gene            complement(95098..95985)
                     /locus_tag="JOX41_000224"
     CDS             complement(95098..95985)
                     /locus_tag="JOX41_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAY6447998.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(96062..96607)
                     /gene="nusG"
                     /locus_tag="JOX41_000225"
     CDS             complement(96062..96607)
                     /gene="nusG"
                     /locus_tag="JOX41_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HAY6447999.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(96708..96878)
                     /gene="secE"
                     /locus_tag="JOX41_000226"
     CDS             complement(96708..96878)
                     /gene="secE"
                     /locus_tag="JOX41_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HAY6448000.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(96902..97054)
                     /gene="rpmG"
                     /locus_tag="JOX41_000227"
     CDS             complement(96902..97054)
                     /gene="rpmG"
                     /locus_tag="JOX41_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAY6448001.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            97216..97860
                     /locus_tag="JOX41_000228"
     CDS             97216..97860
                     /locus_tag="JOX41_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAY6448002.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(97916..98419)
                     /locus_tag="JOX41_000229"
     CDS             complement(97916..98419)
                     /locus_tag="JOX41_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HAY6448003.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(98432..98478)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            99016..99981
                     /locus_tag="JOX41_000230"
     CDS             99016..99981
                     /locus_tag="JOX41_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HAY6448004.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGDDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(100080..101252)
                     /locus_tag="JOX41_000231"
     CDS             complement(100080..101252)
                     /locus_tag="JOX41_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAY6448005.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMPTIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(101239..102384)
                     /locus_tag="JOX41_000232"
     CDS             complement(101239..102384)
                     /locus_tag="JOX41_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAY6448006.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(102398..103322)
                     /locus_tag="JOX41_000233"
                     /pseudo
     CDS             complement(102398..103322)
                     /locus_tag="JOX41_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            103439..104518
                     /locus_tag="JOX41_000234"
     CDS             103439..104518
                     /locus_tag="JOX41_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAY6448007.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            104550..105143
                     /locus_tag="JOX41_000235"
     CDS             104550..105143
                     /locus_tag="JOX41_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAY6448008.1"
                     /translation="MTKSLQTILESTKEIRVLGIGHCAKDALVLYETHRPDVLLTDIR
                     MPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYLIKQNLQAIIPSV
                     KSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKEVAAGKNNKEIAD
                     ALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(105253..105480)
                     /locus_tag="JOX41_000236"
     CDS             complement(105253..105480)
                     /locus_tag="JOX41_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAY6448009.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(105583..108171)
                     /locus_tag="JOX41_000237"
     CDS             complement(105583..108171)
                     /locus_tag="JOX41_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HAY6448010.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(108191..108850)
                     /locus_tag="JOX41_000238"
     CDS             complement(108191..108850)
                     /locus_tag="JOX41_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAY6448011.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVAQHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(108899..109402)
                     /gene="trmL"
                     /locus_tag="JOX41_000239"
     CDS             complement(108899..109402)
                     /gene="trmL"
                     /locus_tag="JOX41_000239"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HAY6448012.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(109623..110489)
                     /locus_tag="JOX41_000240"
     CDS             complement(109623..110489)
                     /locus_tag="JOX41_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAY6448013.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            110598..111239
                     /locus_tag="JOX41_000241"
     CDS             110598..111239
                     /locus_tag="JOX41_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HAY6448014.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(111301..112662)
                     /gene="mgtE"
                     /locus_tag="JOX41_000242"
     CDS             complement(111301..112662)
                     /gene="mgtE"
                     /locus_tag="JOX41_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HAY6448015.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(112680..113579)
                     /locus_tag="JOX41_000243"
     CDS             complement(112680..113579)
                     /locus_tag="JOX41_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAY6448016.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(113581..114378)
                     /locus_tag="JOX41_000244"
     CDS             complement(113581..114378)
                     /locus_tag="JOX41_000244"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HAY6448017.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(114356..115060)
                     /locus_tag="JOX41_000245"
     CDS             complement(114356..115060)
                     /locus_tag="JOX41_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HAY6448018.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            115191..115767
                     /locus_tag="JOX41_000246"
                     /pseudo
     CDS             115191..115767
                     /locus_tag="JOX41_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
     gene            115885..116562
                     /locus_tag="JOX41_000247"
     CDS             115885..116562
                     /locus_tag="JOX41_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HAY6448019.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
     gene            complement(116641..118449)
                     /gene="pepF"
                     /locus_tag="JOX41_000248"
     CDS             complement(116641..118449)
                     /gene="pepF"
                     /locus_tag="JOX41_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HAY6448020.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(118625..119623)
                     /locus_tag="JOX41_000249"
     CDS             complement(118625..119623)
                     /locus_tag="JOX41_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HAY6448021.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(119849..120502)
                     /locus_tag="JOX41_000250"
     CDS             complement(119849..120502)
                     /locus_tag="JOX41_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HAY6448022.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
BASE COUNT        35800 a        24990 c        20657 g        39365 t
ORIGIN      
        1 tttcgtcaca ttcccctttt tcgtatccta ttttaagcga cttgcttggc ataacggttc
       61 acgttttgct tgatattccc gattgttttc ggatcattga ttcctgtgac ttcttgaatc
      121 aattgttcca agttttcatg gatcttcatt tcatgcaatt gacggctttg ttcatcttca
      181 ggatcatagt aattaaaaat aatccccatt gttgccgtca aatgtgggca agtcaagtta
      241 tgttcttgta gttctctcac tggacgtgta aatctttctt gataacctaa cttacgtaat
      301 ggtgtccgag cgacacgtgt gatcgcatca gagatatttt tgttttggaa gcgatgaatg
      361 attttttcaa tatacgcatg atgctgctct gcatcaaacc cccatttggc aatcagcaaa
      421 cttcctgttt cctgcaaaac tgattttaat tgtgccacaa ctaacgcatc ttgcattgct
      481 tcatcaatgg tctggtaacc taacaaggca cctgtataag cgacagtcgc atgaccagta
      541 ttgacactaa atagtttgcg ttcgatatat ggttctagat catctacata taaaacccct
      601 tttaattgga tttttttatt ttttctttgg ctatcgtcaa tgacccattc tttgaaaggt
      661 tccacttgga cgaataaagg atcttcatgg tgttgtaatg ggacgattcg atcgactgct
      721 gcatttggaa agccgatata tttgtcagta aatgatgttt ccggaagata tttatacact
      781 tctttttcta gaaatgctga accgccaatc atattttcac aggcaatgat atctaaagat
      841 gttgtgcttc cttccttttc tctttcttgg ataccttttg caatcaactc agcaataaaa
      901 ggtaagatat tcgggccaat ggcggtagta actaaatctg cttcagcgat ttcttggatt
      961 actttttctg gatttgtttg attgttgatt cctttgacat tttttacagt gattttttct
     1021 tttgattcat ctgctaattc gatttcgtat tcttttcttt catttaaagc atcaatgatc
     1081 gtgtgattca catctacgaa agtaatctca aatccattag ctgccaaaac ctctccaata
     1141 aatcctcgac cgatatttcc tgcaccaaaa tgtactgctc tcatttttct ctctccttaa
     1201 gcaattgcta gattttccgt tacttcttct ttgctgagcg cgtctgctag ctggacaaca
     1261 ttgtccatat cactgcaata aagtgcgatt tgctgtacaa gttgcaaatg ctcatctccg
     1321 actcctgcaa taccgaacaa aacagtcgca atcttttctt cttcttcggt accaaaatct
     1381 acaccatctg gtacttgaac gacacagatg ccggattttt tcacatattt ttttgcttca
     1441 tctgttccat gaggaatcgc gataaaattc cccatataaa cagataacat tttgtctcta
     1501 tctaccatgg catcgatata ttcctcatca acgccccctg cttctacaag catctgaccg
     1561 caatagcgga tcgcttcttc tttggtttta aaagatcgat tgagctcgat catgtcgaat
     1621 ggcaaacttt gcatgctgtt ttcctccctt aagctgtctg tttcaaatat tgtgcaatcg
     1681 attcgtattt ttgcggattg accatgctgt tgactgataa atgaatggat tgaggtgcag
     1741 ccatctgtac tttttccgct aaactttctt tggctacgat cagtgaatca ggttcatctt
     1801 ttaaatcttg gatattgact tttcttaacg ggatagttaa atggttcttg tctaatatat
     1861 ctttgagcac ggtcatcccc attgttgctg atccggaacg atcatcgtgg acaagtagaa
     1921 tctctttgat ttgtttgatg tttgctgaaa gaaactcttc tgctggctca ttctcaattt
     1981 cagaaactga tgttttctgc ttgctgctta attcttgaat gatttcatca tatcgaggtg
     2041 aattcaaaaa gttttctact gagacaaaac gcgcgctcgg tgctttttgt tttgctcttt
     2101 cttgtagttc gacctgagta acgatcaatg tattcgagtc atctgtcagt tggctgattg
     2161 cttgattggt caccgtttga ggcaagtctg cttcctgtac tttttttctc aagatcgaag
     2221 cgcccatcgc acttgatccc attcctgcat cacaagcaaa aatgattttt tgtacgccag
     2281 agaatgtagc tccttgagga ataccttggg cacctttgga agcttgctta gctgcctttg
     2341 tctcttgaac agatttttcg aagtcttcat ttgtatcttt cgcatccgct ttcaaaatta
     2401 ctgcagaaat accaaacgaa acagctgcgg caacaatcac gcccaaaata acaggaaggt
     2461 aagaattgaa cggtgtcatc gctagaatcg caatgatcga ccctggagaa gctggcgctc
     2521 ttagtccagc atccatcaat tggaaaatga aacttcctga cattcctccg cctataactg
     2581 ataagaataa taacggtttc atcataacgt aaggaaaata gatttcatgg atcccgccta
     2641 aaaagtgaat gatcatggct cctggtgctg aagattttgc tgctcctttg ccaaacaaag
     2701 taaaagcaag taatacgcca agtcctggac caggatttgc ttcaagcaag aatagaatag
     2761 attttccagc ctctgctact tgttcagttc ccaatggtgt caaaatccca tgattgattg
     2821 cattattcaa aaataagatt tttgctggtt caataaaaat acttgtcaat ggaatcaaat
     2881 gggcagataa aatgatctct acaccttttg ccattgcttg agtcaatgca tcgacaactg
     2941 gaccaatcgc agaaaaacct aataacgcta atccaaaacc gataagacct gctgaaaaat
     3001 tattgactag catttcaaaa ccggatttga tccgtttttg gaatagctga tcaaatttct
     3061 tgatggcata tccaccaaga ggtcccatga tcatcgcgcc tagcatcatt ggaatatctg
     3121 ttccgacaat cacacccatc gttgcaattg ccccaacaac tgatccgcgg tcaccagcaa
     3181 ttacttttcc gccagtataa ccgatcaata aaggaatcag ataagttagc attgggctta
     3241 ccatggtagc caaagcctca tttggtaaat aaccatctgg gataaataga gccgttaata
     3301 caccccaggc aatcagtgct ccaatatttg gcatgaccat gcttgataaa gtactgccta
     3361 atttttgtac cctcgctttt agcgaaatgt tgtttttggg aatcgtccgt tccattttgt
     3421 ctctccctct ctccttttga tactctaatt gtatccgctt actaaaaaga gaaatagtcg
     3481 tactttggca cgaaactttg tgccaaaggt ttgagtatgt cagcaaaata aaaagatttc
     3541 ggtatcagaa aacttcaatt ttaaataaaa ctgttatttt aattttttta taatatgcaa
     3601 acaataactt ttgttagcat ttaatttaga tgttttccat tctattatgt tattaaattt
     3661 tatattggag gcctatctat gacattactg atcaaaaaca tgaacatgaa acgtggtaaa
     3721 aaacgtgtga ttcgacaatt gaatctttta gtagaatcag gagaagtagc tgctttgatt
     3781 gccccgaacg gatttggcaa aacaactttg ctgaatggca ttgcccaact gctgccaaca
     3841 acttatgatc aattgtccct tcacaacatc tctcctactg cttatacaga ttatcgccgg
     3901 tctttctttt ttctagaatc aacgaatcag ttatccgact atctatcggc tgttgattat
     3961 ttgactttga tcaaatacta ttggcagagc aaagtagaat gccaaactgt tttccaacga
     4021 ttgaagatga ctgagtacct tactttgccg attggaaaaa tgtctctagg aatgaaacaa
     4081 catgtcttgc ttgctgctta cttgatcagt gattcatctg tcatgttatt cgatgaaccg
     4141 ttgaacggat tagacccagg aagtattgat atcttgaata gcctcatcag acaatggcag
     4201 aaagagggga agacgattct tctttcttcc cacgctatcg cgaatatcca atcgatttgt
     4261 tctaaagcat gttttctaaa aaatggagaa atcgtcacag aatcctcaaa tatggaagag
     4321 attttagcta tttatcgtaa attatatgag gtgtaactat gtctttactt acatttgaac
     4381 gcaatctctt actaaaaaac aaagtaaact ttttatttcc tctattgttg gtcgtgctct
     4441 ttgcattccc actttttttt gatcataaac ttgcttatac agaattcgat gaactgaatc
     4501 ataactatga agagatgcaa cgtttgattg aaacgttgaa agaagatgag aatgagaaag
     4561 aatttgtgga aagtttagag aaaagcaaca aactgatcga agcaatctta catgcaaaaa
     4621 acacagggaa tgtccagcaa atggtcgaag caacttatca ttatgaaaaa gatatactgg
     4681 atcgactgat ttctggtcaa agacaaggaa ttccaatcat tgaacaacaa aaacgtgtcg
     4741 agttgctccg ttatatgaaa gaacatcaga tccaaagata ttctattttt gacttgccag
     4801 cgcatctccc tttagcaaat tactacgaaa atattttttc aggaatgatt tctagttttt
     4861 tgattttatg tataaccgcc ttgtttcttt cttccatcat ctcttatgaa aaaagaaagc
     4921 aggtaatctc tctagtcaat ctattaccgg atagtatggt aaagaaacat agcatccgtt
     4981 ttaccattta ttatggtgca gctatgctaa gtctcgtgat gccatttttg atcgtctcta
     5041 tactagtaat aatcaaaaat ggtttgggag acttccgtta tcctgtagga acgatcattg
     5101 gtcaggagat acgaatcctt ccgatgtatg agtatctttt ccagagcttt ctgttcctgt
     5161 tgttgtgggt gctcttttta agtacaatca gttttcttct atctgcttta tttgaacatt
     5221 ctctagtcaa tcttttaggt acacttcttt gtcttttctt agcagagtat cgcttgtttt
     5281 cttcgattgg atggatagaa tcaatcagtc attacttgcc aacttcttat gttgattttc
     5341 aaaatgtgat cataggagga gatattttct cgccactagc ttcagaacag gttactttca
     5401 tgaatggtat cttgacactt ggtatatgga gtatcgtttt attattcata ggtatgggca
     5461 ctatctatat aaaaaagagc tattaaaaca caaaaataat aggggcggtg acaaaaacct
     5521 tgtcaccgtc ccctatttca aataaacggt tttctagaat aaatagtttt caaaagcttg
     5581 catccgcagt aataagaacc tcccaacaaa aatagctcct cttattttta tcttggttga
     5641 agttattact tgatgcaagg cagctttttt tactgtgaac attggttata tatgtccatg
     5701 ttcaaaaatc atttggactt cttcaatggt tttcgcatca ctgagcgcca ttacttggtc
     5761 gatgtctgaa cagaaaaagg ctaaatcttg gagcaccgct aactgatgtt ctttttttaa
     5821 agccactaca aataagagtg tcgcgatttt tggttcctct tttgttccaa agtccacacc
     5881 atcaggcact tggactaaat agattccttc ttctactact tcttcatctt tgtcagtccc
     5941 atgtggcaag gctacgaaat tcccgatata gacactcgct ttttcttgtc tttcgatcat
     6001 tgattggata tatgccggtt tgattccccc ttgttgggtc atccactggc cgatctcggt
     6061 caacgcttct ttccaatttt gataggattg atcgagcaat attttttctg ctggtagctg
     6121 tatcatcttt tcaccttcat ttctttattt cttcaatcag gattttcgct aacaactgat
     6181 aaacgatttc tttatttcct gagcggaaga tctcggtgtt caagtcattc atgatgattg
     6241 ctccactgat ctttcctaaa agaatcccgt ctttttcttg gattggcgaa ggcgccagca
     6301 taactaacat acgggacaaa tcgactggct gtctatccat cccttcaatg gtcaacggat
     6361 gtttcaaatt gaaaatacaa aagatcggtt tagaaatcaa tgagctggat gtatggaata
     6421 accccatatt tgtatgagga ataccgatag gtgcttgttc atatcgctta agcagccggc
     6481 gatgaaccac ctcttcatcc gttactagtc cttcaggaaa ataaggaaat aagctgcgaa
     6541 tcgtttcgga aatcgtctca ggattatcca gttcttggat aaaaaaacga ccgagtaatt
     6601 gattgatttg atccatgaaa tgcattgttt cctcataagt atcttctatc atccactcgt
     6661 tattgctgtt atacgtaatt ttttgccttt ttttcttctc aatatgcgaa aaagcttctt
     6721 ttagctgctt gacttcatct tctagcagta gcggggagac taaaatatat tttccaccgt
     6781 atcctggtaa aatagatgta gaaataacaa catcatattc ttcttgtaaa tcgatttttt
     6841 ttaaatcagc aatccgatag aaatgaattt gttggatgaa gggaaaatac cttttcaatc
     6901 gtagttccaa catgctagta gaagctaatc cacttggcga aaatcctgca atactgatat
     6961 tgctttcttt cggacttcgt tccaatgaat tcgcaaaatg aaggaccata taagcgatct
     7021 cttcttcgga taattttttt tcttgaaaaa tccgctctac tgctttacgg attgcattcg
     7081 caacttcctc gtattgaacc atgatttttt ctaaaatcgg attggtcagt gtctcttctt
     7141 gtaaaacggc tcttgaaaac acaccagata aatgagtcaa cagcattttg tacaaagttt
     7201 catcttcata aaaatggaca ttcgtctctt cacttacttc ttgaatcagt tgttttacta
     7261 aataagcaag ctgtgtatcg aacgtctctt caaagaaatt ctgatcaaat gagttcgtga
     7321 agtcatttaa taatcctgca aaaaagacga tctcatttac tggataaagt tgttttgtct
     7381 cagaagcgat ccgtgaaaac aatcgtttag ctgtctgtag taattctttg tttgccagac
     7441 tattatatgt ctcatttgtc agtaaatgat ttttagtcac acgctccatc gtcaatgtca
     7501 gcatcaaaac caaatgttca agctttctat cacttagatt ggtctttttt tggatcaatt
     7561 cttccccgat tactttgcgt gcaagagata gatgttgcgg atcaacgaat cgaaaaaaat
     7621 aattcagtga tgcatcgaaa gaaatactat gaaaaagttc atattcattg atttctaatt
     7681 ctaatacatt cgctgtcaga agccggcggt atttttccgg tccttcgatc tcgtatccct
     7741 ggttccgaat gatttccaaa ggcagttggc gaatactttc ttccaactgt ttgatatctg
     7801 cataaaaagt ggtattactg atgcgatatg attccatgaa atgagcaaga ctcaacggct
     7861 ctgtcgtcag taacaactcg gctaaaatcg cgtgttgtcg tttagcagtg gataagtcat
     7921 tacttttccc atctgtattt tcttttaatt gctctaatac ttcttctgat gcctcaatga
     7981 caaatgagcc tctagctgct tttttcaaag aagcatttac cgatttcaat gagacttcaa
     8041 gattatctaa ttcgcggtaa atagtccgtt tactgacctt caataaattc atcatttttt
     8101 ggatagatac aggtgacggg ctactgagaa attctgctaa taattgtttt tctctgggcg
     8161 ataaatacat cttatatttc tcccttcacg agtttttcgt attcattcgt agctacccaa
     8221 tgttcaacta gaactagccg agggatcttt tcttctagct gttcagttac agctagttct
     8281 ctttgtgcga tataaatcgt ttcttcttgg attttgattt tttctattga ttcttttgag
     8341 ataacaaact gttttttcgc tttttttgct aattgactta aaatcgtcat gcccatagtt
     8401 tgtgagccgc gtctgttgtt tttatacaaa aatacaatat tagcaggcga ctttttttgt
     8461 tctgtgatat ctgctatctc ttttttttct tcccgctttg gaaattggat cgcttctttt
     8521 attcgtgaca gcaagatatc tgtttccaaa aagtgatcca gtacatagat ttgactttga
     8581 ggtacttttt ctcttgcaag acccgctagt tcatgttgca cgataaccag ctgatttact
     8641 tggttattca attcatagat agagctgtat ccgacagaaa gatcgatttt ttctgctgct
     8701 aatttctttt tcagcagggc ggctcccata gcacttgatc ccatacctga gtcgcaagca
     8761 aaaatgacgg aatgaatgat agatggttcc aagatttctc ccctttcttt gaccgttttg
     8821 ttctcttttt ctttatttgg taatttcaat agtatcgctg cacaaatgaa ggtcacaaat
     8881 gtactgattg ctatccctat acttacccca gctagttgtg gataaggcgc attggcaaaa
     8941 atcacgagta gtgacccagg cgatacaggt gcagctaatc ccgtatctaa ccattgaaat
     9001 atcaacgtgc cgcttgcccc accagccatt acagctaaaa atagatacgg tcgcagcaag
     9061 acaaatggaa aatagatttc gtgaatcccg ccaatcgcat ggatcatcaa tgctccactc
     9121 gcatttactt tttcctgttt ttctgcaaaa caaaggatag aaagtaagat ccctaaacca
     9181 ggtccaggat ttgcctccat caaaaataag gaagagtacc cgactgtttg tgagaattcg
     9241 attcctaaag gtgtcaatac accatgattg attgcattat tgaaaaatag tacttttaga
     9301 ggttctaaga tcagactgac aagtggtaac agattcattg tgactagcca agacacaacg
     9361 gaggcgagca acaagtgaac actatttaaa actggttcaa taaaaacgat tccaattata
     9421 caaataacgc taccagtcag tcctactagt aggttgctga caagcatttc atatccagcc
     9481 ttgaatttca cgtggaatct agaaacaaat tgttcatata cgatgccggc aagcggcccg
     9541 ataatcatcg ctcctacgat ttgtggagca ttggaacgag cgatcaaccc taaagaagca
     9601 attgcaccgg cgactgcccc tttttgtccc cctaccgatt tcccgcctga ataactgatc
     9661 aagatgggta aaagcagctg gatcatccaa tggcatacct cttctaatgt ggtgtgcaaa
     9721 tcgccagaca caccttttgt tgctaatgac aagattcccc aagcgataaa cagacttaga
     9781 tttggcatga tcatttcatt taagtgatgt ccagcttttc tcagttgttt catagacacg
     9841 cgactgctgt tgtttgcttt ccatttgtat tccatctttt tcaccatact tctatttatt
     9901 gatggacgga ttttatgtag aaaaagcagc aaacgaaaaa ccgtctgctg ctttcagcta
     9961 tctgggaact atttgcctgg ttcagtcgca atgattgcta gttcaccttg gaccgcccac
    10021 tcagaaacgc catttggaat aatacagctt gttccttttt ctaatggata tgtttttccg
    10081 tcaacgacaa ggtctcctgc tccttcgatt accgtcatca atgtataagg ggcttgtttt
    10141 ttgaaagatg tgattccttt aatatcccac tcatatacat tgaaaaactc agtttctaaa
    10201 taagtgacga tcgatgaatt cccttttcgg acttctttga tttgtaattc tggtgttttc
    10261 gcagggacag ttgttacatc gatcgattgt tggatatgca gctctcttgt ttgtccttgc
    10321 gcatcttttc tgtcgtagtc atacacgcgg taagtcgtgt cagaactttg ctgtgtttct
    10381 aaaatcatga ttcctttacc aatagcatgg atcgttccgc ttggtacata aaagaaatca
    10441 ccttttttaa ctggtacttt cttcaaaagg tcatcccagc gcccatcttt gatcatctca
    10501 gctagttctt ctcttgtctt tgcatgatga ccatagatga tttctgcacc aggttcagca
    10561 tcgatgatat accagcattc agtttttcct aattcacctt catgtttcat cccataggca
    10621 tcatctggat gtacttgtac agatagatca tcttctgcgt ctaagatctt gatcaataat
    10681 ggaaacactg gttctgaagg atggccaaac aattccttgt gttctgacca tagttcatct
    10741 aatcttttcc ctttgaattc gccattttct actacactga caccatgagg atgcgcactg
    10801 atcgcccaat cttctccgat tttatcgtta gggatatcaa aaccaaagac tgaacgtaaa
    10861 cgacttcctc cccaaatttt ttcttgaaaa actggtttta aaaacatagg ttcctgcata
    10921 attcaaactc ctctcatttt tcatagctat tatagcatta tttcggtaat accgttttct
    10981 ctttcaaaaa gttttcaaca atttcatctc gacatatgag atactccgca cgatgatcga
    11041 caggatgtac gcgatttgac aaaaatatca acgcttcttg tgtttttata tcaatcaaga
    11101 aaaacgtacc tgtataacca gtatgaaaaa gaatcgcatg accgtcttct acatcctttt
    11161 ttaagtccca tcctaaagaa cgatagccat tttttttcgg tgtttgatct tgcagtaaag
    11221 aatcaatcgt ctcttcttct aaaaaacgac cattacggat ttttcccttg ttcaaataca
    11281 tttggacaaa agtaatgctg tctttcaaat caataaagag acccgcgtta cctgcatgtt
    11341 cagccaaaac tcttgctttc ggatcatgag tttgtccacg caaaacctca cccgaaggca
    11401 gttgttctgt gggaacgatt tttttggaag gaaaaggaag aaataagctg ttcatcattc
    11461 ctaatggttc caatacttgt tcttgaaaga tttccactgc agtttcttgg taaatttcct
    11521 ctagcatcaa cccaagaaga atcgtaccgg catctgtata ttttacttct tttcctagtt
    11581 gctcacctgg ttctagcttc aaataagcgg cgatcaattc ttcctgagat agcttatctc
    11641 tgtttggtat ccatgttttg atatcagaag tatgtgtcag taaatgacgc aaagtgattg
    11701 tctgattttc aaattcagga agatatttat gaagcggttg atcgagttct atctttccat
    11761 cttctaatag acgtaaaact aatgaagtgg ttgcaacgac tttcgtcagt gaggctgcat
    11821 caaacaacag atcttctgtc atcagctgct tttcaggaac gacttgggca aagccggctg
    11881 taaatgtttc tacttgattt tcttttatga aggcgactgc tacacctgga taaaatcctt
    11941 cttccatctt tttcaaaata agctgtttcg tgtgtggata catctttttc tcctgctttt
    12001 ctatcagatt cttacagtcc aagcttaaag cttaatctat gaggaatcaa ccttttttac
    12061 acaaaaaaac tgcgcgaaaa accgcgcagt ttcccccggt atactatttt ctctttctat
    12121 ctctagaata agcgatagta tgaccgttca taaaatgacg agacatgcga caatcgttaa
    12181 gaaagaaaaa gttaagcgtc gcatcgaatg tcagttttat tcttttcttt tggctcactg
    12241 acgaaccacc attcgattcc tatagcatca tagattgtga gtactgtgtg ctttttgtct
    12301 aagaagaaat caactgatag ttgctgcaag tgagcaatca gtccttccat gctttcagta
    12361 tcgatcatga atttcagaaa atcaagtcca atcacttcat ctgtaggcaa atcaattgcg
    12421 cctccgctag cttctgtcaa accaacatgg aaatctcctt cattcaatac atggatgccc
    12481 tcttcttcat tatgtacctt caaaccaagt acatgattaa gaaattggcg ttcttttgtt
    12541 aagttagtaa catttaaatg gattttttca aaataagaac ctgttgatag tttactgaat
    12601 ttttcttcag attttcttaa taatgcttct tgatccattg tttctggaat ttctctttgg
    12661 tcgttcttat tctcttcatg gtaaatttcc aattcattct cttctgggtc tacgagcaaa
    12721 atccccatac gtccatgatc ttctaaagct tctttgattg gataattcat tttacggata
    12781 cgacaaagga tatctgccat ttcttctgtg ctagggataa tcaatgaaaa acggttcagc
    12841 tttttgatca cccccatgtg atcattcgct ctaggacttt cttccagcag caacatttca
    12901 cttccagctt cttctgttcc taaaatggct aattcgtttt cttctctttt caaatcaaag
    12961 ccaacaacgt tcttgtaaaa atcaatcatt ttatctcggt ctttcacccg aatggctaca
    13021 ctttttaaat aggtggcagc ccccaattga aaatctttca tatttcttgc tcccctctac
    13081 gtcaagcttt attttaacga tggattcttc ttctttcaag caataacttt gattttgtta
    13141 aaaaaaatgt gagaaaattc gcattttgct tgttttttgt aaattaatga gtaaaaactc
    13201 ttataaaaag aggttgtgaa aaagctgttc tgcatcaagt aataagaaca gccaaacaaa
    13261 aatagctcct cctatttttc gtttggttgg gcttattacc gcagatgcaa gcttttgaac
    13321 accgtttaag gaagaggttg taaaatcagc ggtttgacct gagtattaga gatacaaaac
    13381 ggaaaaatag cttctcatat tttgccgttt tttgagctaa taccgaagga cagctgattg
    13441 aacaccgttt attcggaaaa agggactgtg acacgacttt tgtcacagcc cctaaaaaaa
    13501 ataataaatt tgtactattc tatgaagctt cttcttcaga aaactgactg ttataaagat
    13561 ctgcatagaa tccgtctttt tccatcaatg tatcgtggtt tcctgtttct acgatcgaac
    13621 catgattcat cacaataatg ttgtctgcat cgcgtattgt agacaagcgg tgagcaacaa
    13681 cgaaacttgt ccggttttcc aataggcggt tcatcgcttt ttgaatcagt atttctgttc
    13741 gtgtatctac actagatgtt gcttcatcaa ggatcaggac atctggattt gctaagaatg
    13801 cccgcgcaat tgtgattagc tgacgctgcc cttgcgaaat attgcttgca tcctcgttta
    13861 atacagtgtt atatccttct ggcaatttac gaacaaaatc gtctacgtga gcagctttag
    13921 cagcctcaat gatttgttcg tctgttgcat cgtcgttccc atatttgata ttgtcataga
    13981 tacttcctgt aaacagccaa gtatcttgca gtaccattga aaactgtgcg cgcaattcat
    14041 cacgtgaaag atcacgggta tctacaccat cgtaacgaat actacctcca gaaacatcgt
    14101 agaaccgttc aagaaggttg atcagtgtcg tcttccctgc accagtcgga cctacaatag
    14161 cgaccatctc accaggtttg acatccaagt taaaatcagt cattagcaag ttatctggtg
    14221 tgtagccgaa ttgaacattt tcaaaacgaa ctttgtatgg tgtatctttt tcttctggaa
    14281 ggccagattt ttcattggac atctcttctt catccaacac ttcaaatacc cgttcggctg
    14341 aagcaactgt tgattggata gtgttcatca aacttgcaag ttgagtgatt ggttgagaga
    14401 actgtgttgt atattgcaag aacgcttgaa catcccctaa tgtcatgttc ccatttgcaa
    14461 cttttactcc gcctagtaca gcgacgaaca catagcctag atttttaacg aaattcatca
    14521 acggcatgat gattgccgaa ataaattgag ctttccaacc agcggcatac agattctgat
    14581 tttctttttc aaatacttcc tggtcttttt cagtatgatt gaatgtttta acaatggtat
    14641 gaccaccata tgtttcttct acttggttat tcaataaacc taaacttttt tgctgatctg
    14701 cgaaaaacac ttgtgatttc ggcgctacga tcatcacgat gatcaagctt aaagggatca
    14761 tcaataacgc gactaacgtc aattgccagc tgattgaaag catcatcacg atgaccccaa
    14821 tcaatgtgac tgcactagtt acaaattgag tcaaattttg ctgcagcgtg cttgcgatgt
    14881 tatccatatc attgattgct cgagacatga tatccccatt tgtatgtgta tcataatagg
    14941 aaatcggtac acgattcatt ttggcttcca aatcatgacg taattcataa actgttcgtt
    15001 gggaaacacg tgtcataata aattgctgta aaaagttgaa tacagcagaa atcaaataca
    15061 tcacgattac tgtcgcaatg atctgcgcga ttttatcaaa gtctatcgga aattttgtta
    15121 cttgttggcc ttgttgcatc tgttgagcgc cagccattac acctttgaat atttctgtgg
    15181 ttgctttccc caagaccttt ggtgtttgga tttggaagat cacggctgct attgctagta
    15241 caaatacagc gatgatcgca accatacgtt tagacatata gccaaacaat cggcgtaccg
    15301 ttccccagaa atttttaggc ttttcacctt ttacaccgag atttctgcca ggtccaccat
    15361 gtcctggacc gcctgctggt ccatgagagg gacgtgtgtt tgttttactc atgctaagtc
    15421 ctcctctctt agttgtgaat gaacgatttc ttgataagtt tcgtttgttg ctaatagttc
    15481 ttcatgtgtt cctttgccaa ccagttttcc ttcatctagc acaaggatca tatctgcatc
    15541 cattactgta cttactcgtt gagcaactaa aacggtgata ctttctttca tattcgtttt
    15601 caatgcttgg cgaagattgg catccgtttt gaaatccaac gctgagaagg aatcatcaaa
    15661 cacatagata tctgctgttt tgactaatgc ccgtgcaatt gccagacgct gtctttgtcc
    15721 accagagaag tttcctcctc cttgttccac atggctatct aagccatctt ccatctctga
    15781 aacaaaatct ttagcttgtg cgatttctaa tgctttccaa atcatttcat ctgttgcatc
    15841 cggcttacca tactgcatat tgtctcggat cgttccagag aacagaactg ctttttgagg
    15901 aacaaagccc attaattctc gcaaattata ttgagtcatg tcactaatgt ccgttccatt
    15961 tatttggatc gaaccagatt cgatgtcata taatcgaggg atcaaattga ctaaggtcgt
    16021 tttacctgaa ccagtccccc ctatgattgc gacgatctcg cccgacttgg cttggaaatc
    16081 aatatcttcc aatgcaagtt tttctgctcc atgatatcga taattgacat gattgaaggc
    16141 caatgttgcg ttttttccag caaaagaaac tgttttagga ttttcagggt catggatacc
    16201 gattttttca tccaacactt cattaatacg gtcagctgaa gcttgtgcac gaggcaccat
    16261 gataaaaata gcggaaagca tcataaagct gatcaagatc tgcatcgcat aagtcataaa
    16321 tgcaatcaga ttaccgactt ccaaagtcat atctgctatg tagtgtccac caaaccaagt
    16381 gattgctacg tttgtaccgc tcatgatcaa tgtcatcatt ggcatcatca atgcgacgat
    16441 cgtattaact ttgattgccg tatttgtata atctttattc gctaaatcaa aacgattttc
    16501 ttcaaagcgt gtcttatcga atgctcgaat cactctgacc cctgtcaatc cttctcgaaa
    16561 taccaggttt aaacggtcag ttttcttttg catacttttg aataatggaa cagcaaagta
    16621 catgattccg ccgatcaaaa taatcattac tgggatgaca actaagaaga tttttgtcaa
    16681 ctgatgatct ttttgataag caagtatgct cgcgccaatc aacgtgattg gtgcattgat
    16741 catcatacgt aaaaacattt gtgtaaccat ttggatttga gtcacatcat tggtcgttct
    16801 tgtgatcaaa gaggccgttc catatttatc aaacgcatct tttgtcagac tctctgattt
    16861 tttatagaca tccgtacgca attgcttacc cagtttctgt gattcacgag tagcaaaaaa
    16921 tgtatttgcg atagcagcta agatactgat caaagaaaag ccgatcatca caaaacctgt
    16981 atgccaaata taatcgacat ctccttgcgc taccccttta tcaataatat tggaggtaag
    17041 tgtcggcaaa tataaatctg ccagtacttg gatcaccatg aaaactgcag ctgcaattgc
    17101 tgaagtcaag gagatccgtt ttacgatttt tagcatctag ttcccttctt tctatttata
    17161 tactccgttt ttcagccaag aaagtttcaa attgaattca ctgattgctt gctctactga
    17221 gtaatcttca gatgttgaaa ataagcgata cgaatgcgca attgttgtaa atacagtatt
    17281 catcactaat tggatcagta attccaattc atgatcattt tttactttca gcttcgtccg
    17341 atcgatcaat tcaagcaact cttttgcatc ttgtttgtgt tctttatgtg gatcgtgagg
    17401 cgttttttgg cgactcgtat gaggagcgac ttttcttgag gcacggtaat ccatgttcat
    17461 aaacaagtta cgataaaaag aagcattctc gccttccaaa atctcataaa tcattttaga
    17521 aaaataggat tcgaatcctt tgaatagatc accatcggat tctttcatta gttgtaacat
    17581 atctttagag ctgtcacgtc tcattgtctc aaagtaataa aaataaagat cctctttatc
    17641 ttcaaaatac tgatagaaac tgcctctagg gatatccgct aatttgacga tattagcaat
    17701 cgaagcttct tttaagggta ctctagaaaa ctcgattctc gcagcctcga ttagtctttt
    17761 ttgtttttct ttaggcaaat ggaaaaatgt ctgtgtcggc atatggatcc tcctttcttt
    17821 caagatgaca cattgtcata tgacgctgtg tcattataac acctcctacc tgttttgcaa
    17881 gacatttgca tagttttttt cattatcatc cgatacatta aaaaagtgat aagaggaatc
    17941 cttccatttg aattaatgag agttgcccat taaaatagcc acatactaaa caaaggatga
    18001 gataaatggc ccaatcaatt agtgtccaag acttcaataa attgcctctc gatgctgaca
    18061 gcatcgtttt agatacaaga aataccttag attacacaaa aaaccactta agccactcgc
    18121 tttctatccc cgctgctatc ttgccaagac aattaaaaaa tctagatcca aagaaacttt
    18181 attatattct aagctataca ggcaggcgat cagaagcatt agccgatcaa cttactgcta
    18241 atggttttcg tgctgtttat atcattggtg ggatggaagc tcttcagtcg agtgttgctt
    18301 gaatattgct tgttagattc aaaagaggct gtgacaaaaa atcgtgtcac agcctctttt
    18361 ataccctgtc tttttttagt tatttattct tcaaccttat caatatgact tgatagcctt
    18421 ttctttttct catagttata acaatcatag caataaaagg agaaggtaag catatggcat
    18481 ctgttttagt agtcaaaggt catcccctaa ctgcagaaga atcgcgcaca gttaaggcat
    18541 tgacgtcttt tttaacaagt tataaagaaa atcatccaga tgatgaagtg actgttttgg
    18601 aactttatcg cgatgatatt ccggaaatcg atgaagaatt attatcaggt tgggaagcat
    18661 tacgtgctgg tgcagaattc acttccttat cagaaagtca acaacaaaaa attgctcgtt
    18721 tcaatgaatt gactgatcag ttccttgctg ctgataaaat cgttatcgca aacgccttat
    18781 ggaatctaaa tatcccaaca aaattaaaag cttggttcga taccgtcaat gtagctggaa
    18841 aaacgttccg ctatacagaa aacgggccag aaggattagt gacaggtaaa aaagcactgc
    18901 acatccaatc taatggcggt gtatacaacg gacaagactt tgcctctcaa tatgtaaaag
    18961 gtattttaaa ctttgtaggc atcgatcaag tagatcagct attcatcgaa ggaatcgatt
    19021 atgaccctga ccgtgcagat gagttgatgc aaaatgcatt agataaagct gctgctttag
    19081 gtaaatcatt ttaaaaattg agataaatgc atacaaaaga gacagaggaa aaaatcttca
    19141 aagcagcatt tgtaccttgg atattttccc atctgtctct ttttgttatt ctttctgctt
    19201 tttcaacgga ttttcttcat aaagagaaga gattgttgtg taccattcaa aaacatgagt
    19261 aatcactact ttagctgctg cataaacagg aatccccaag atcacaccga tgattccgaa
    19321 caatttccca gaagtcagca gaactaataa aatcgttact ggatggattg ctaactgatt
    19381 ccctagtact aatggagaga tcaagcgtcc ttctattgtc tgctctactg caaaaacgat
    19441 cagtactttg atgatcatga atggacctgc tacaatggct aaaaagatag ccggaatcat
    19501 cgctaaaaat gatcctaagt aagggatcag gttcaaaaaa cccgcaataa tccccaacgt
    19561 gacagcatac tctaaaccaa tgaccgcaaa accaatcata aacatgattg ccacagcaaa
    19621 agccacagtt agttgtcctc ttatataaga agaaacttga ctattcattt cactcagcac
    19681 attcaacgtc ggtttttgca tgcgtgtcgg taaaaatttg acaaaataag gtgctaattg
    19741 tttaccgtct ttcaatagat aaaataagat aaacggcatc gtcagcagag ccactaaaat
    19801 agtcgctacc gcgccgacaa aacttccaag actctgaact gtactcttag atatatcttg
    19861 gatcatatcg cctgccgaat tcatgaactt atcacctgct gtttccaact gttcgcgaaa
    19921 ttggttgaac agcgggtccc gcaaaatctc ggttaattta ttatcaatcg tatctacata
    19981 ttgagggaag ttactgatga agctcactgt ttgttcctga atcttaggga tgatcactac
    20041 gctcccccat gcgattagtg caacaaccaa aacaaacagc ccaatgatac tgtaaagcct
    20101 tggtactttt cgcttttcaa agtaatcaac taccggattc atcaagtaat acaagattcc
    20161 tgctaaaatg ataggcagac ctacgattgc taaaaattgc cagattggtg caaacaaata
    20221 tgaaactttt gtaaataaaa agacgatcag caatattaac aatacaacaa gtaaggctgt
    20281 gactacttga ttatttaaaa accagcgcca aaaccacgat accggtctgt tcttcttatt
    20341 ttttccttcc ataattcctc ctgttagtta taaaaaattt ggcttcccaa accaatagca
    20401 ggcagtctat gcggatgaag atagattcca tttgcaattt gtccttcttc tggacaagca
    20461 tcaaaaatca atgatacgtg agctactgtc tctaaattcc cattggccat cggaccgaca
    20521 taatcgatcg tatatacctg atcatcaaaa gcaattgttc cgcctgcttt caaagaaaaa
    20581 ggttcgtctt ttgatacttc ttgaatcacc gaatattttc gtaaggcagc tgttgctgtt
    20641 ttatcgaaca aaatcagcat gggttcttcc ttgtttattg cttctgtccc aatttctgta
    20701 atctttgcct gaatcattgc actctctcct ttaattgctt tcaaaaacag tataacacat
    20761 tctcattctt tagccgtgtg gaataattat gtgatagaat aaaaacgaaa actatttcat
    20821 tacaattagg aggaatcagc tcatatgatc gaaaagataa ttttaggaac ctatacgcgt
    20881 cgcgaaagta aaggaatcta tacgatcgac cttgatacag aaaaagaaga attagccaac
    20941 ctttcattag ctgttgaaga aaatagccct acctatgtag caaaaagtaa agctggcaat
    21001 ctttacacag ttactagtgt ggatggatta ggtggtgccg gtgcgtacga taaggatttt
    21061 cattttttga atgcggtaac agagtctggc gctcctttgt gttatgtagc ggttgatgaa
    21121 gcacgtcaat tactatacgg ggcgaactat cataaaggtg aagtaaatgt ctaccatata
    21181 ttaggagatg gcgaactgaa agcagcagat tcaatattcc atcaagaagc gacaggtcct
    21241 cataaaaacc aagatcatgc gcatgtccac tatacggatc tgactcctga ccaacgatta
    21301 gtcgtatgtg atcttggtac agatcgtgtg tatacttatg atgtgtccga aaacggcaaa
    21361 ttgaatcttg taactacctt cactgcagag ccaggaacag gccctcgcca tcttgtcttt
    21421 catccaaatg gacaattcgc ttatttattt ggtgaattag acagcacagt ccgcgtgctt
    21481 tcttataata aagaaacagg tgcttttgaa gaattacaga aaatatcgac cttgccagaa
    21541 gaattcgacg gtgaaaatgg aggggcagct atccgcattt caaatgatgg caagttcctt
    21601 tatgcttcta accgaggaca taactcgatt gctgtattcg cagtttttga agatggttcc
    21661 cacattcaaa acaagcaaat catctcaaca gaaggggatt ttccccgcga tttcgcacta
    21721 gatccaagca ataattttgt cgtgtgtgcc aatcagaaca ccgataatct gacattatat
    21781 cgccgtcatc ctgaaacagg attactggaa ttactgaaaa aagatgtcta tgtaccagaa
    21841 tgtgtctgtg tttattttga tcgttagtaa gaaaaggaga atgaaatgaa tcagcaagac
    21901 gtattagaca gactacggga agaactaaat attcctttct ttgatgggaa aatcgaagat
    21961 aaagagtata gcgaagagga atatcagaaa ctcaaagccg atttacagaa ctactttgaa
    22021 caatatgtac agaatgtaga aaactaatca gctttccata ctatctgaaa agaacatcag
    22081 gacaagactt ttccgtctat cctgatgttc ttttctacaa ataaaaaacc gccgagatgg
    22141 ttagactcga cggaaaagga gtatttactc gattttgagt aagtacaagg ttgttgttgg
    22201 ttataggtat gtcattatca taaaggattt tgatcactct atcataaagg taatattaca
    22261 tttatattag ataactctag tttttattgt tatcaaagat ttcttttatt ttttcaacaa
    22321 caaattagtc attttttgga tggcagctgt caattggtct gtcgcttggt cttgttttgc
    22381 ttcagatgta ttgaatagat cttcatctac ccctgattca agatcgatac tttggatcat
    22441 ttcttcacag cctgctacat atgaaagata agctttttca aaatttttat gaatgcccat
    22501 tgcttttgct ggtggacgca aagtactgac tttcttaagc attgcccgat atttttttgt
    22561 tccttcttca aataacagga tgatctcttc aagagtcgat ttgtccagtt cacttgtttt
    22621 tccttcatca attgcgtttc tgatcacttc atatttcgga tgcattcctt ctccgattgc
    22681 ttctgtttcc ttgacgattt gatcgatgga ctgcacataa tagccaatat tcggtaacat
    22741 gttcgttttc ctactttctc cattgttgtt attatttatt ctacttgttt ttatcctcaa
    22801 atgacaagta cttgaaaaaa tttaatggtt tctatacagc tcgccattct tattcgtgct
    22861 caaagaaacc atctgctaaa ctatattgtt tccctgcgac aatgtcatat tggatcaatt
    22921 gatattcgtc gtaaatctct tgttgcgagc gattgaattg cgcttcttta taccactgtc
    22981 cgttttgata gtacagttct cgttcaaacg ccggaagttc ctgttctaat gataaaagca
    23041 gctgataaaa gccatttgtt gtctgattcg tctgttccat tagattcgct gcaaaataaa
    23101 acggactggt gattgcatcg tgagtcgttt gcttttctaa ttctccttta ctgtcgaaca
    23161 taagaaattg tgtttcatgc aatgtttgtt tgtcattttt tgcttggatc gtatctgaat
    23221 agatccctgg aagatgatcc ccccaaaaaa caactaaagt ccttctagaa agattcttca
    23281 attcttccgt gaactgcttc agtgccgtgc tgctatagga aatatcttgc agataattct
    23341 ctaagtcaag tgtcccactt ccatctgaag tttttgcagg atagtctaga ttatcatact
    23401 ttccatcgta gggcatatgt gtctgcatcg tgactaaatg aatgaactga ggtgtttttt
    23461 cttccttgag aagtgtcatt acttctttgt aagctgactc atcagaaata tatggattat
    23521 tctctatcgt atccgtatag gtcatcgtac gctcgctgat gaactggtca aatcctaatg
    23581 tctgataaac atcctctctt ttatacatcg aagtattgta tggatggatc gctgtcgtct
    23641 ggtatgattg tgcgtttaac gctgaaacga tagaaggaag ctgatccatt tttggtacaa
    23701 gcatcgtgta aggggtggtg agttgcgcat taaataacgc catagaaaaa ccagtcaatg
    23761 cttcaaattc gatatttgct gttccaccgc catagttttg agaaagcata ttgccactat
    23821 atgtttgatc agctacttca taataatctg ccaatggctc accagatact tctacgccgt
    23881 ttaatcgact aggatctgag aaactttcac tcatcacgaa cacgatgttc ggcgactctt
    23941 cctctacagt tttatttttt tcatcggcta gcttctggta tttttcagtg atttctttga
    24001 tcttttcttt cgaatatcct tcaggttcat ccattggttc taccttcaga ttgtacaaaa
    24061 acccaccgat aaaaccagtg ttatagtagt tcattttctg gctgtaaggt atccatagtg
    24121 ccgttttatt atatgctttt cgcaacaaat tatcgggatt gttgaaatta ctgatatacc
    24181 ctagcagtcc aattgccaca agcagtgtcg ttaatcggat caattggaat cgccttcctt
    24241 ttttcaggct tcgaaacatg taccagcaaa acaatcctat cacggttcct gcggcagcta
    24301 agatcactgt aaacagcata gtgccggtca tatctttcag caatccgatt tcagtgatca
    24361 tcttcaaatc gtctggataa atcggttctt gccgataact cattttcata taatttgcaa
    24421 aacctaatac accgatggct acgacatacg taagggaacc taaagggaca gatcctgcta
    24481 gtgcaatcag aaaaataaga ataatcagca agacgagaca ggctaagaag aatttttccg
    24541 tatgccaaga aaaagcaaat ttcaacgcaa ggtctacgga tagatcattt tgacaccact
    24601 gcaaaaataa attactaaaa acaacaagaa aaaagatact gatgattgct gctgttcctt
    24661 ttaaaatctt tttctgtttg gtcgaaagtc tgcttatata tcttttcaaa tgcttgctcc
    24721 ttcatttcta tcaataaaag aatgttgctt ctcttatttt agttgtacga aattcgaaag
    24781 taaagaacgg aaagaagaat taatgaaatc caaatattct ctttctttat ggcctttctg
    24841 gtttctttaa taagcggacc tttcgtactc cagaaatttt ttctagctgt tgtttcactt
    24901 gattgagctg ttcaaaatca gtactgtcta tgtcaatcaa tatgtagaca tgctcattct
    24961 tatggttacg cgatatatct gcgatcgcta gctcgttctc attcagcaga gaaaatatct
    25021 ctgctaatat attggttttc ttttgataaa atatagtgaa tcgaaacggc gcttggaaaa
    25081 acattcgtgc ggatggataa ttgaccgctt ctctaaccgt accgaacaaa agataatctt
    25141 ttaaggcttc aactgccaaa cgtccgctgt ctgccaaagc ttcctgagtc gatcccccta
    25201 gatgaggcaa cataagtata cggtcatttt ctaagaactc ttcttctgga aaatcagtca
    25261 agtatttagc cagatgttgt ttttccaatg cttgcataac agcatattta tcaacaattt
    25321 cacttcttcc tacattgata agtacagcat cttttttcat tttttctata ttcgcctgat
    25381 cgatcaatcc ttttgtatct tctgtcaacg gcagcatgac tacgatgtaa tccgaggtag
    25441 aaagaactgt ttctaaatct gcttgccgaa cataatccaa ctgggcatcg cggatagaat
    25501 aacccaagac atccatccct aagctatagc aacttagcgc tacttttgtg cctatcgctc
    25561 caagaccaag aagaccgatg gttttgcctt gcaattctcg tcccacataa gcacttcttt
    25621 tgttttctgc ctgttctaaa atattaggac ctgttagtgt ttgtaccata cgacttgctt
    25681 cgattatcgg acgggaagat aagagcaaac agcacaaaac aagctctttt actgcattag
    25741 catttacacc tggtgtattc atgacgatcg tcccgttttc agaagctttt tcaacgttga
    25801 tcgtgttcac cccaacacca gctcttgaaa ttgctagcaa atctggtgta agccattcat
    25861 ctttcacttt cgtactacga ataactattc cttcggctgg caaatcatct attattttga
    25921 aatattcccc ttgtaacttt tctatctctt gttctggaat agcatcaatc aaatgaacgt
    25981 gatacataaa accccctcct tactaacaag tatctcgaaa tttctgcaat tagacaactg
    26041 tttaccattt gacttcctag aagcaaaaag agcagttaga gcagagtagg ctgagtgata
    26101 aaaataaggc tatgacaagt tactgccata agccttattt tcgagagcaa aatattgagg
    26161 gtgagatatc ttgataaatg gtgttccgtt agctgacatt gataataaga ctaaatttca
    26221 aaaaagttga aaagcaaatt tcgtcaatct cttcttattt cttaaaacta agtggctttt
    26281 tcacaacctc tttttatcta ataaccactg tttccaactc aactaatttt gcccacgttt
    26341 caatttgatc tgttgttaga tttagcgaga caacggtatg atgaccgcca cctgcctgaa
    26401 tccatgaatg gacaccttca tggaaattcg gtttagtttt ccataacaca cgtgcaacag
    26461 gtaaattagg tgcttcagtc gttggttcaa aggcttctac ttcattgatc agcagtttat
    26521 aatgcgtacc gaaatctgcc atcgatacga ctaccccttc tcctgctttc ccatcaaata
    26581 caagacgcgc cggatcttct ctatctccca ttgataaagg agaaacaacg attcttggtt
    26641 tcgtcgcagc aagcgtcgga tctacttcca tcatatggga ttccaagatt gcttcttggc
    26701 cactagctag ctcgtaagta taatcttcca tgaatcctgt atctttccct cgagccatga
    26761 ttttcagcaa ccgatcaatc gctgcagttt tccagtcgcc ttccccagca aaaccgtatc
    26821 cttctgccat caaacgttgt acagctagtc caggtagttg tttcattcca tacaggtctt
    26881 caaaattagt cgtaaaagcg ttatagcctc cttcttctaa gaaacggcga ataccgattt
    26941 cctgctgagc ttgtactttt acatgttcct cccatgtctt ttcttcataa tcaccatagt
    27001 cgaaggtata caattccttg tactcttcaa ataattgatc gacttcttcg tctgatacgc
    27061 gatcgattac ttgtacaaga tctccgatac caaaataatc aacagtccaa ccaaattgaa
    27121 tctgtgcttc cactttgtct ccttctgtga cacccacgtt tctcatgttg tcaccaaaac
    27181 gagccacttt tattccaaaa ctttcattat aggctactgc aacatccatc caatcagcaa
    27241 tctctttttg gatctcaggt cgtttccagt agccaacgac gattttattt tgtttattta
    27301 atcgagcatt gatgaaccca tattcgcggt caccatgagc ggattgattt aaattcatga
    27361 aatccatatc gatcgttttc caaggaatgc tttcgttata ttgcgtagct aaatgaagca
    27421 atggtttttg tagaagcttt gtcccgcgga tccacatttt tgctggtgag aaagtatgca
    27481 tccaagtgat cacacctgct acttcttctc gataattgac ctctttcatg atttttgtga
    27541 tcgtatcagc agtaactgct aattcttgaa ggcggattgg ataaggcaat tggccatttt
    27601 cattcagttc atcgaccatt tcttgtgcat gtttctttac ttctcgcagt gcttcttccc
    27661 catataaatg ctgtgatcct acaacaaacc aaaattcttt ttctccaata ttcaacataa
    27721 ttagccactc cttttatttg ttttgtccgt aatacgcatt ttttccgtgt tttcgtaaat
    27781 aatgtttatc taaaatccgt tgaggcagct cttctgaaaa tgaattgagc tgtctggtaa
    27841 ataaattcat cttgcatact tcatctagta cgactgcgtt cattaccgca ctttgcgcat
    27901 ctttccccca agtaaatgga ccgtgtccgt gtaaaagtac ccctggaatt gctaagggat
    27961 caattttgcg ttctttgaat gtttctatga taacttttcc tgtttcatat tcgtacccgc
    28021 tgtcgatttc ctgttgtgtc aaaaatcgag cacaaggtac cgatccataa aaagtatctg
    28081 catgcgtcgt ccccatcgca ggaacatcca atcctgcttg tgcccagatc gtcgcccatg
    28141 tcgagtgagt atggacgatt cctccgattt gaggaaatga acgatataaa acagcatgag
    28201 taggcgtatc cgaagaggga ttgagtttac cttcaatgat atgattgtcc aagtccacaa
    28261 cgaccatgtc gtctgctgtc atctcttcat aactgactcc gctaggtttg ataacgaaat
    28321 atcgtgtttc aggatcaaaa gcgctcacat ttccccatgt atatttgacg agtccgtgtt
    28381 taggcaagtc aagatttgct tggtatactt cttctttcag ttgttccagc attttctatc
    28441 actccttttt cttgcaattg atgaatcgct gttttttcaa tgtcgatccc ctcacggtaa
    28501 cgtctcataa atatctgata gcctgctatt tcttctgctg aaggtgtgat ggtgattcct
    28561 tggtcttgtc caaacacgtc ttctgccaag aagttttcta aagacttccc atgtcgatcc
    28621 atcatatagg ctgctaataa cgcgattccc cacgctccac cttctccggc tgtgtccatc
    28681 actgtaactg gtgcctccat agcagatgct agaatccgct gtccaacttc tggtgtttta
    28741 aaaatccccc catgccccac taaacgatca atttggacat tctcagattt caatatatcc
    28801 attccgattc tcattgcacc aaaagcactg gctaaatgga tccgcatgaa attcgctaaa
    28861 tcaaaacggc tacctggtgt acgtacaaat aatggccttc cttcatttac tcctgtaatg
    28921 ttttcaccgg aaaaataacc ataagaaagt aatcccccgc aatccgtatc gccttctagc
    28981 gctttgttga ataataccgt gaataattta tctctgctta tctccatacc caaagaattg
    29041 gtaaattctt caaaaatact gacccaagca ttgatatccg aagagcagtt attcgtatga
    29101 accatgccta ctagttctcc tgaaggtgta gtgaccatgt cgatttccgg atggacattt
    29161 tctagttctt tttctaatac gatcatagcg aaggcggaag taccagccga aatgttccct
    29221 gtccgtttgg ctacactgtt cgtagcgacc ataccggttc ctgcatcccc ttctggcgga
    29281 caaaccggga ttcctggtct caaatttccc gtagggtcga tcagataagc ccctgattcg
    29341 cttaacttgc cagcttcttc tcctgctact agaactttag gcaaaatgtg atccaagtca
    29401 atcgctacgt gcgctttttc gattaactga ccaaaaatat ttttcatttc ttgatggtag
    29461 gttttcgttg aaggatcgat aggaaacatg cctgatgcat ctcctacgcc tagtactttc
    29521 tcaccagtaa gctgccaatg gacataacct gcaagcgttg tcaaaaaatt aatttctttc
    29581 acatgttctt ctttattcaa aatagattga tacaaatgag cgatactcca tctctgcgga
    29641 atattgtatt gaaatttttc cgttaatatt cgttctgctt cttcagtgat tgtatttcgc
    29701 caagtacgaa atggtactag taactgttcc ttgctatcaa atgctagata accgtgcatc
    29761 attgcactga acccaatcga cccgattgtc gtaagattct cgccatagat ttcgaatact
    29821 tctgctgcca tttttcggta actgacgcgc agtcctttcc aaatatcttc taatgaatag
    29881 gtccagatac cattttctag tttgttttcc cactcataac taccagcggc aataggagta
    29941 aaagatgaat caatcaatac agctttgatc ctagttgatc caaactcaat ccctaaagat
    30001 gtacgaccat ctatgacatc taacatactt tgcgcattta cttccttcat aatgatttaa
    30061 ctccctcctt ctcgtcaaac ctgatcaaac cgtcttttta gtagcgctta caatgattat
    30121 tgtatacttt tgtacgtaca tgtcaagcgg ttatttacaa gaatacaata aaaaacactt
    30181 gttttgtacg tacataagtt ataaaatgaa attgcttaca aaatctgatc aaccgccttc
    30241 tcgaaattct agaaggagag aatacttatg aaaaaagaaa aaaaagtttc ctcatcgttt
    30301 atttattttt ttggcgcatt tggcggcatt ctatttggat atgatattgg tgttatgacc
    30361 ggcgccttac cttttttaca gcatgattgg ggtttggcag gtaaagcttc tttgatagga
    30421 tggatcacgt cttcggtcat gttaggtgcg atccttggcg gctctttatc tggtcttctt
    30481 tctgataagc ttggacgacg aaaaatgatt cttctttctg cacttatttt tatggctggt
    30541 tctgtccttt ctgcatctgc ccctcacaat ggttcttatt ttctgattgc agcaaggatt
    30601 cttctaggtt tagctgttgg cgctgcatct gccctagttc ctgcttatat gtctgaaatg
    30661 gctcctgcta gactaagggg aagattgtca gggatcaatc aagtgatgat tgcttctggc
    30721 atgctccttt cctatgttgc agattatttg ctaaaagtgt tgcctgaaac gatggcttgg
    30781 cgcgtgatgt tagggctcgc tgctgtcccc gcgctgattt tatttttcgg tgttttagct
    30841 ctaccagagt caccgcgttt tcttatgcaa tctggccgct tggaagaggc aaaaagagta
    30901 ttgaactata ttcggacacc aaaagaagct gaacaggaat tcgaacaaat ccagctgaat
    30961 gtcaaacaag aaaagacaac cggaacttct tggcatactt tgtttttaga aaaatatcgt
    31021 tccttagtca ttgccggtat tggtgtagca gtattccagc aatttcaagg agctaatgct
    31081 attttttact atattccgct gatcgtagaa aaagcgactg ggcatgcagc gagcgatgca
    31141 ttgatgtggc cgatcatcca aggaatcatt ttagttgctg gttctttgct ctttttggtt
    31201 attgcagaca agttcaatcg gcgaacttta ttgaaaatag gcggtagcgt gatgggactt
    31261 tcattcatcc taccagctgt tttaggaact gtactggatg ctcatacaaa ttcgttgttg
    31321 attctcttgt ttttatgtat ttatgtcgca ttttattctt gcacatgggc tccactgaca
    31381 tgggtaatca taggcgaaat attcccacta gctgtccgcg ggcgagcatc tggcctagcc
    31441 tcttctttta attggattgg ttctttccta gttggcttgc tttttcctgt gatgactgct
    31501 tctatgtctc aagaaatcgt tttcggcatt tttgggatca tctgcttttt aggggtttta
    31561 tttattcaag agatcgtacc agaaactcgt gggaaatctt tagaggaaat cgaacaaagt
    31621 gcatctaaaa aaacttatcc taaacgtatt tctatccatc attcttaaag aggttgtgac
    31681 agaagtggtc agcttcaaga aataagaagg aaccgcttag tttccagtca caaggaacaa
    31741 tttcaaaaaa cagcttctca tgtttgatga atattgtgac ttgtgaccag ttggtaggag
    31801 aacaccgttt agtggagagg tggtgaaaga aacgttcagc cttgagcgat gacaaaagct
    31861 ctcacaaaca ttgcgacgag taaccgtagg agcaataaga ggcggtaaaa acccgtctct
    31921 tatttttcgt tttctttcac tgtttcccgt tcaactagta caggttcata gagaatattt
    31981 ggctgtgcct gtcctttttc aatcgttgtg acgatccacc gtgcggcatc ttgtcccaac
    32041 ttttcttttg gatgcgtcaa tgttgtcaat tttttattcc ctaaatggct taaagaagaa
    32101 tcgtctgttc ctacgatcga taggtcatct ggaatatgat agccattttc tgtcaactta
    32161 tctagcatta aactagctat ttgatcgtta tagcaaatga tgccatctaa agcttgttct
    32221 tctttcaacc gttgtactgt tttttcagcg attgtttctc gtgtttccgt ggtgaaagta
    32281 atgatatctt ccgtcaaaaa acgcacatta tactgttcac acgcgctgat aaaacctttc
    32341 atcctgtatt ttccttgaag atcgtcgatt tttgtgatga acaacagacg ctgatgtcct
    32401 ttttttatca aatattctgc tgccataaaa ccgactttca catcatctaa acaaatataa
    32461 gaggcattta actcttcata agcagcattg atcatcacca tcggaatgcc ttgttctctc
    32521 aaagcaacat aaagtgctaa gtttgggtta tactgattac ttttcgtagg ctcaacgatc
    32581 aaaccatcta ccccataagc aatcattttc ttcaaacact ctttctccaa ttcgtgatcg
    32641 ttattcgtac tggctaaaag caatgaatac ccagattctc gtaattcatt ttcgattcct
    32701 cggataatcg acggaaaaat ataatcagag agatatgtgg tgatgacacc gatcgttttt
    32761 gttctgttca atggtgtttt ttctttctta tagctgtcat ctacatatgt gcccgaccct
    32821 ttttctttac gcagatagcc ctcatttacc aacacagcga ttgcttgccg aatcgtatgt
    32881 ctgctgacgt catatatttc ttgcagcttg aattctgagg gaatggttgt atttacttcg
    32941 tattcctcac gaaggatctt ttgttttatc tcttctgcaa tatcttgata ttttgccatt
    33001 tgccttgccc ctttttattt gtacgtacat atatcataac gagtctgcaa ggtttattca
    33061 agcaaaaatc aaggtttctt gtgctcataa ggcatacgga acaggttcac caaattctgg
    33121 aaatccttgc tcattccacg taaagcattg cgcgttcgcg tgccgattag gattgtctaa
    33181 cggatcccct ttttggttct tctctggtcg agcatgatag atcaaaatat caaagcaccc
    33241 gtcttctgaa accgtaaacg agttgtgacc aggaccaaat tgcttatttt tttcagaaga
    33301 aacgaatact ggctccgata atttatgcca tgattctttt aataaaagat tcttgtgctc
    33361 atcagcccac agcaggccca tggcatagtt ttcatctgtt gcactaccag aatacgtaat
    33421 gaatattttc ccattgcgag taaggactgc tggaccttca tttactgaaa aaccccgttt
    33481 ttcccattca tactcaggta tagaaaggag gatctgcttc ccctttaacg tccaaggatt
    33541 atccatttcg gatagataaa gattagaatt cccagtaatt tcaggatctt gttgggccca
    33601 cacataatat agctttcctt gagaagagaa agttgttccg tctaaactga aagtttccct
    33661 tttcgttttt atttgtccct tttctatcca atctgtattc attggatcta tatgctgatt
    33721 ttcaagtacg aacatgcggt gatgatgaga ttcatcacgt atagttttat gattgcttgc
    33781 agcaaagtaa atataccatt ttccattgat ataatggact tcaggtgccc agatcaattc
    33841 actcatcggt ccttcttcat gagcctgcca tacaatcagg cttgcagcat gttctaattc
    33901 attcagtgac tttgcccttc ttaattcaat cacttggtag cctggaaccg atcctgtaaa
    33961 ataataataa ccatctgtat gtttatatac ccaaggatct gcccgttgcc gaacgatagg
    34021 attattataa agtgtcttca tcataacaaa tttcctcaca ttttctttat tctaattaca
    34081 ttccaagagt atttttctat ccctacattt aattcgtcat gtttttctat tgaaaaatag
    34141 tttatttcag gttttatttt ttctggttct tcacgtgtat ttttgtccaa cagatcgcta
    34201 ctggttaatg tgtagtgctc tccttgatct agcaaattga aatcatgttc aatcgttatc
    34261 ttttgttgtt catttgtgcg attgatcaag aaaatagtca gctgattgcc gttatctacg
    34321 atcacactgt ccacataagg aacatttttt atcttttcac aatcataaac agggcaaatg
    34381 atttgttgtt tcaatacttg acctttagca tatttcgata agtgttgcat cacataataa
    34441 gttggattcc tccatgcttg tcctttagca tctgtcagta ttaaaggtat tgtgtttact
    34501 aacaatgatt gacaactaat ctttacgcga tctgcgtgtc gtaaaatagc cagccctaat
    34561 gaaccaaata ataatgtatc ttccatagta aagtaacacc aatcgatggg actaccgact
    34621 tcaaaatccc tatgtctttt ttccggttgg gcatgtacat tccattcatc aaacgctaga
    34681 tacattgttt tctcacttct caaatatcct tttacataat cacaagtagc aacgatttct
    34741 tcaatttgac gatcgaatcg ataagctttt gcaaggtatg tcgctgtatc atcacgctca
    34801 tttttaggag gtttagtcaa gtcttcttca tcatacttat caatatagtt atgcaaagct
    34861 aaataatcta cattctcata agcttcttct aatgcgatac gatcccattc agggtacgat
    34921 ggtaaacgtg gcgtagagct tccaactaag attgtttcaa ttgaatcatc cactaacttc
    34981 atgacttttg aggcttcatt tgctaaccta ccatattcat aagcactctt agcccccact
    35041 tgccatggac cgtctagctc attccctaaa caccataatt taacgccaaa aggctttttt
    35101 tgcccatttt ttattcttaa atcactccag aaggttcctt ttggaaaatt acaatattct
    35161 actaaatttt ttgcttcatc aattcctttt gttcctaaat tcaccgtgaa tatcggtttc
    35221 gcttgtacat gactgatcca tttaaaaaat tcgtggagtc caaaagaatt tggttctata
    35281 cctcgccatg ctaaatcaat tttttttggt cgttgttctt tcctacctac agtatccacc
    35341 caatcataac cagatgtaaa gtttcctcca ggatagcgaa tgacacctaa ttctaattcc
    35401 tttacataag agaggacatc ttgtctaaac ccgtcaccat cagctgtttc atggcccggt
    35461 tcataaatcc ctgtatagac gacacttccc atatgctcaa caaatgagcc aaacagccga
    35521 gaactgatct ctcctaccgt aaaatcctct ctgattttta ctttcacttc ttcgtccaac
    35581 agctttccct acctttcatt tcctatagtc aagataatag atacaagttt ccatacgcca
    35641 ccagcaaaga taaaaataaa aggagggaaa agaaatatga gcagtacaaa tcctaataac
    35701 aatacgcaac aaagaatatt tctcaaaaaa tcaaaaaata ctttccatgc actttgttca
    35761 aaaatttgta aaaatgtgat atctttgttt tcagaaatca catatatcca ggataaaaga
    35821 aacatggaat aaataagtaa aactacatat ccactaattg aaagtacgat tgtctgttct
    35881 tctaataatt gattaacaag aaaataaata atgatcgtta acagactaag gaacaagttc
    35941 ttaccaaaat gttgctttat tccttgaaag aaaaaataaa tgatatttcc tgatccctca
    36001 cctttccatt gcgccattac ataaaaaaca gcacatgtag caggcacgat agtaataaca
    36061 ggcaaacaca cgattaccca gagaatacct aataagatgt aatcagaaac cacaatcaac
    36121 tgtccataaa atttagtctc aactattttc atcttcctca ctctttcatt ccagacatag
    36181 ctgttccttg aacaaaatat ttctgtgcaa aaatataaac cactagtaat ggcagcattg
    36241 aaataaccgt tccagccatt acaggtccat aaaaagaaat gttctgccct gtaaataaag
    36301 ctaaccctgc tggtaaagtt ctcatttttg aactacttgt caatatcaat ggataaagca
    36361 agtcattcca actattcatc agcgtgaaaa tccctaatga taaaagagta ggtttgctca
    36421 atggcaacat gattttcaaa aaaatattaa actcacttaa tccatcaatg cgtgctgcct
    36481 cttccaaaga atctggtaaa gtaataaaaa aggaacgcat catgaagata ccaaatgcag
    36541 ttgtcatacg aggaatgatc aaacctgcat aagtatcaag catgccaagc aaattgactt
    36601 caataaatag aggaatcatg aagacttgga atgggatcat cattgtcagc aaaacgaaat
    36661 agaacaaaac tgattttcct ttgaaacgca tacgagcaaa tgcatacccc gcaagagaat
    36721 caaagaatac agaagtgatc actgtccctc cagcaaaaat cactgtattt ttgatgtaat
    36781 ctaataaagg gatcgttgtc caaaccttaa tatagttatc tagggtatag ctatctgcaa
    36841 atattctagg cggaaatgag ataatgtctt tttcgtgttt aaaagaagaa ataatcagcc
    36901 acaaaaaagg aaacgcaata accaacaata taactagcat actaatcgtt cgaatgattt
    36961 ttttaccact aactgctttt cgactattca cagtaactgt aatcgagctt tctggtgcca
    37021 tacaggtttc cctcctattt catttgtttt tctttccgtg acatgtacac attagtggag
    37081 atagctatag ttgcaacaat gataaacaaa accgaagaca gtgctgatgc atagcccaat
    37141 tcataaggtg ctgtaaatcc tcgactgtaa atatattgaa cagctgtttc tgtcttaaat
    37201 tgtgggccac cagcggttgc aacatatact tggtcaaaca cttgcatcga accaatcaga
    37261 ttcgttaaaa tacaaaaacc taaggaggga acgatctgag gtagcgtaat gttaaaaaac
    37321 tgctgtcgat ttgttgcacc atccatttga gcagattcat acaaagaggg agagattccc
    37381 tgaatagcag tcaagagaat cgtcatagta acaccaaaat tcttccaaac agtcatgatg
    37441 gctaccgtcg gcatagcaag ggttggatcg cgaaaaaatt gagggatcgg caagccgact
    37501 tgtgaaaaca agtaaggaat cgcccctaca ttcggatcaa gcaacataga aaaaataatc
    37561 gcaattgacg tcaatgaaca aataactgga atgtaaaatg tcgaacgaca aaaacgattg
    37621 aatctggtat ttttagataa tgctactgct gctaataaac caacgataat ttgtgttggc
    37681 gtttcgagta cggtgaaata taaagaatga atcaacgaat taactgctcg ttcatcacta
    37741 aatatacgtg tgaaattttc aaaacttaca aaatttcttg atgtaaagaa aatattcaaa
    37801 tctgtaaaac taatagcaaa tgttcctaaa agcggtatga cagtaaataa taataaaact
    37861 aaaaaagatg gagttaaaaa caaatacgca gcacgatcag gacgattcca atatttggtg
    37921 aatccgttca tatagtccac ctcatctttc attttgataa aatatacaat cttggtttaa
    37981 acgaatctga ataagatatc cgaacaatcg ctgtgatttt tgcaataaca cctatctgca
    38041 aatactaggt cgatcattca gatatctgta tcttgccaac agtctatcct gtataaagtt
    38101 ctgtactatt tttgcagtaa ttgattgatg gcatcatctg catcgttcat gagtgtctca
    38161 ggatcttctc ctgctaataa tttttcaatc agtggattga tgatatcgtt attgatcgca
    38221 gagatttggg taaaacctgg taaatatggc tctgcatagt ccatttgttt cgataattca
    38281 gatacaatag gatcattttt tacttcttca tcttttgcta ctgaatccaa gtaggcagga
    38341 aaaccatttt cgatactcca ttttttacca atttcagttg tattccaata tttcaaaaac
    38401 tcatagacag cttctttttt attattatct gtacttgccg gaatggcata tcctacgcca
    38461 tctaaaatag ctgttttttt gtctgaatca ctcccttgtg gtaaggtagt cacattataa
    38521 tcaatctcgt ttgctttcaa tccgttattt aaccatggcc cattgatttc aatggctagt
    38581 tgaccagcat tcattaaatt gtccatttcg gcgccagaaa tcgattctgg accagtcttg
    38641 tctacatgga tcattttttg gatcgctttt aacgttttaa ggttctcagg agacgcaaat
    38701 tcagacttag tataatcatc gttcactaat ttaccgccat ttgctaacat ccagttatat
    38761 aacggtgcag ttccatcctt attgaagaca aaacctgata catttttact actatcagtt
    38821 aattttggtg ccatttctgt caattcttcc caagtagtag gtggttgttc agtatctaat
    38881 ccagcttgtt taaacaaatc attattccaa tacatataca tgccttgtac ctgcatgggg
    38941 acaaaatact gtttaccttc tacttcacct aattcaatag ccgtttcttt aaaatcagat
    39001 ttatctactc catcatattc ccagaaatcg tctaatggtt gtaccgctcc gttttctaca
    39061 tactgtgcaa aatctggata atttaatgca ataaagtcag gtgctttttt agaagaaatc
    39121 gctgtaggaa gtttttcatt caaattggcc caagtcatga tatccatttc aattttgatg
    39181 tttttatcat ttgttttatt aaattcatta acgatttctt gcaatatttc accatcagat
    39241 gcagtaaacc cattccaaaa agtcaaagtc acttctttat cagaatcaga ttctgctgaa
    39301 cttccgccac cgcaagctcc taaaatacct gttgcagcta ccaacaaaga gccaattaac
    39361 cattttttac ctttcatttt ttgttcctcc ttcatctgat aaacgacatc tgaccacatt
    39421 ccaagatagc ggtttcaata aacaattgat tttcccatct tcagctttta catttgttga
    39481 atgacttggt tttacttgtt cacttttagg aagattagtt gcttttgtat caaatccact
    39541 catttcagaa aaatcaatca ctccctctaa tgataattca gacaagtgaa cagttagatt
    39601 catttcttct tctccacggt taactgcaaa tatgacaagt tctttgtcat ttattacggc
    39661 tatactttct aaatacggca cttcttcaaa atcttccgtc gcatagtttg ctgaacgaat
    39721 ttgtgggctt aacacctctc cttgtccata cacagcagct tgcataaatg gataatagat
    39781 cgtctgtctc caagcttctc cgtttgtttc tgtcctgatt ggtgcaataa cgtttaccaa
    39841 ttgagcaaga caagcaatct ttactctatc tgcatgtttc aataaagtga ttaatagaca
    39901 gcctaatagt aatgcatctt caaaattata gttatcttct agtaaaggag gagcaatctg
    39961 ccaaggcgct gcttgctcat cttgttccgc tgaatgatac caaatattcc attcatcaaa
    40021 ggacaggttg atctgcttct tactatgttt cttcgccttg actgtatcgc acatcgctgt
    40081 cacttcagaa atgaaccgat ccatgtctaa ggaacgtgca agataatgag aaagatcatt
    40141 tttttggttg ccataatatt gatgcagaga caaataatct atttgatcgt acgcttgatc
    40201 aagaactgtt aactcccaat caccaaatgt aggcatttgc cgattcgaac ttccgcataa
    40261 aaccacctca attgaatcat ctacgagttt catcgcctta gccgtttcct ctgctaaccg
    40321 tccatattct tccgctgttt tatgtccaat ctgccaagga ccgtccattt cattccctaa
    40381 acaccatgtc ttaattccaa aagggctctc ttgaccattc gaacgcctta aatcactcca
    40441 ataagttcct ttaggaaaat tacaatattc gactaaatta cgagctgcat ctactccacg
    40501 agtacccaga ttgacagcca tattgatttc ggcccccaca tgctgacacc agttataaaa
    40561 ttcatgaatc ccaacttcat tcgtttcaat tgtccgccaa gctaaatcca accttctagg
    40621 tctatttgct atgggcccaa tactgtcttc ccaacgaaat cctgacacaa aatttccacc
    40681 aggatatcta atcatgggaa tgttcaattc ttttaccaag tgaatgacgt cttggcgaaa
    40741 tccactttta ttagctgatg gatgatctgg ctgataaatc ccttcatata ctgctcgtcc
    40801 catatgttca ataaatgaac tgtacaaccg cggatcaact ttgcctacac gcttgacact
    40861 actaatcaac attgtggctt ccataactga cctcctttaa tttatacatg aataatacac
    40921 ctcgttgaaa gcgttgtcaa taatataaat gttaaactta cttatttttt atcgatttta
    40981 attaaccaaa atattaataa tgattaaaac aaataattta atataacttt tattaacaaa
    41041 tatgttaata tataagaaaa accttttaag aggtgatata tatgcaacta caaataaacg
    41101 aagaatcctt accggtatat gaagcattag ctagtaaaac aaggatcaag atcatccagc
    41161 tactttccaa aaaaaagatg aatgtcaaag atttggcaaa agaacttgga gtgagcagtg
    41221 ctatcacgac gatgcacgtg aaaaagctag aggaagcaaa catcatcaaa acagaaaaag
    41281 taggacaaca aaaaatttcg agccttcgtg tcgataaaat cgatattagt tttccagaaa
    41341 aaatattcaa tgcttttgat acgaaagaaa catcgatacc tattggtcac tatacaaatt
    41401 atgcaattga accaacatgc ggtttagcta cgatccatga ttttatcggg aaagtggatg
    41461 aaccacgcta ttttatggat cctcgaagga tggatgcccg cattctctgg tttaccagcg
    41521 gatttgtcga gtatcaggca cctaattttt taaatacaga ggatacattg gagatgttgg
    41581 aagtttctgt ggaaatttct tctgaatttc ctttttcaaa tgacaattgg ccttcagata
    41641 tcactttcag cctaaatggt gtggagctag gaacatggac gagccctgga gattttgctg
    41701 atatccgcgg taaatatacg cctgattggt atccagataa tcttaatcaa tacggcttgc
    41761 tgaagacgat ccgaattacc aaacacttga cgaatatgaa tggagaaccc ttgtcaaaca
    41821 tcacgatcaa cgacatccct aaagagcaag acacttggca tttgcgaatc gaagtgaaag
    41881 acgatgccaa acatgtgggg ggctgtactt tatttggtaa aggattcggt aattacgatc
    41941 aggatatcaa attaaaagtt tactacagct gatatttttc ttttctattt tataaaacaa
    42001 aaacagccaa tccctatgaa gggacggctg tttttgcttt attgttattt ccagaaatca
    42061 tccaaaacgg aaattggcaa atgtcgttta tgttgtgtct tgttccacca tgcttcgatt
    42121 ttttcttgtg cttgagcggg aacttctttt ccttctagat aatcatcaat ttcattatat
    42181 gtgacaccta gtgcgacttc atctgcaatc attggtttcc catcttcaag atctgcagtc
    42241 ggaatttttg tgtataattt ttccggtgca ttcaatgctt gaagcaattg tttcccttgt
    42301 cgtttgtcca aacggaataa tggcaaaatg tcggctccac catcaccaaa tttcgtgaag
    42361 aatccagtaa tgttttctgc agcatgatct gtccctaata cggctcctgc tctttctcca
    42421 gctacggcat attgcgtaat catacgttga cgtgctttga tatttccttt gttaaaatcg
    42481 ctgattccca cacctgcttc gcttaatact tgtacttgtg catcaacagc tggtttgata
    42541 tttactcgca gactaacatc gggctggata aagtcaagag cagcttttgc atcttcttca
    42601 tctgcttgtt caccataagg aagacgaaca gcgataaatt gatagttttc atcttttgtt
    42661 tcttcacgca tttcttccat cgttagttgc gccaaacggc ctgctaaagt agaatcttgg
    42721 ccgccgctga tacctagtac aaaagtttta agaaacggat attttttcaa atatgctttc
    42781 ataaagtcaa tacttttacg tatttcttct tttggatcaa ttgttggttt gacacctaat
    42841 tcattgataa tttctgtctg caggctcatt tattctcctc ctatgcttct gtatgaagtt
    42901 ctgctacgct ttttttcatt cgttccatga tagccatttt atggttccag cattcagtag
    42961 acagatcgac tgggtatttt tgcggattca agtctcgttt atactcttcc catagtgaat
    43021 ctagattttc ttttgtatat tctttgattt cgtttagtgc aggtaattcg taaactcttt
    43081 ttccttcgat aaagatatct tgtaaaactg ggcgagctgt aaagtctcga acagttttat
    43141 tgataaacgt atgcactgga tggaacatga agatagcttc ttcttctcga gggtcttcat
    43201 cccataatgt cacgtagtct ccttcagatt tcccatcaaa atttcgagtg atgcgccaca
    43261 cttgtttttt ccctggagta gttacttttt ctgcattgct tgataacttg atcgtatcca
    43321 tcatttttcc ttcatcatct tcgatcgata ctagcttgaa tactgcacca agggctggct
    43381 gatcataggc tgtgatcaat tttgtcccaa caccccatac atcaatttta gctttttgca
    43441 tctttaaatt caaaatcgtt gcttcatcca agtcattcga agcatagatt tttgcttccg
    43501 taaatccggc tgcatctaat tgttcccgaa cacgcttaga tatataggcc atatctccac
    43561 tgtcgatgcg tacgccttgg aagttgattt tgtcacctaa ttctttcgcc acgcgaatcg
    43621 cacttggcac acctgatttc aacgtatcat aagtgtcgac taagaacacg cagtctttat
    43681 gggttttagc gtaggccata aatgcttcat aatcatttcc ataagattgg actaacgaat
    43741 gagcatgggt cccgctagct ggtatcccaa atatcttccc agcacgtaca ttgcttgttg
    43801 catctgctcc gccgatatat gccgctctag ttccccagac tgctgcatcc agttcttgtg
    43861 cccgtctagt tccaaattcc aatagtggat cttctccgat gacagatttg atacgagctg
    43921 cttttgtcgc gatcaacgtt tggaaattga ccatattcaa cagtgctgtt tctactaatt
    43981 ggcagtgcgc taaaggccct tccacttgga tcaatggttc atttgcaaaa actagttctc
    44041 cttcacgagc agaacgaact gttgctttaa attcaaaatt ttgtaaatac tccaaaaaac
    44101 cttcaggata gacttctaat ccacgcaagt aagcaatatc ggaatcattg aacgtcagat
    44161 tctctaaata attgactaac cgttccaatc ctgcaaaaac cgcgtatccg tggttaaaag
    44221 gcatttctcg aaagtaacat tcaaaaacag catgtaaatc agctcgacct aattcccagt
    44281 atgtctgcat catattgatt tgatatagat ccgtatgcag cgtcaaactg tcgtctgggt
    44341 aagtattatt catcttgtat tactcctctt ggcaagtttt catttcctac ccattataac
    44401 aaaaaaaatt aataggaaaa gaaatcttcc attttttctg aaaaagcaca tgttttacgg
    44461 atatttcttg ctaaaaatga actccatctg ctaaaactat cctttcttat tggtatttaa
    44521 cctaaacgag aaagaatact tattttattc aatgtatccg agacacgaag aaattagcgt
    44581 tttctatttt tcttacttga taaaataagt agattttcct actacaatcg tagccgttaa
    44641 gataccgatg attgaacaaa tataaccaaa tgtctctaca acataatcaa tggcaaaagt
    44701 ttttgaagca ataatacgtc tttccttttt tgcttcttat ccccaaagaa acggatataa
    44761 cttattatgt attgaatttt tttggaaagg cgaattatga caagatatac cttgcgttga
    44821 aaaaactcgc ggaaaaaata tcacacgttt ttaaaaagat acaaagtaag aaagcagctg
    44881 tcaatagaat ggaaacaaaa atggcgagac atcaatcagt ctcgccttgt tttttattgt
    44941 atacattaga tatggagcag gttaccataa agatgattat tagtcgttat taaatagaat
    45001 ccttcgtatt tttttgttct atcactacaa tatctttatt tggacgtttg aattgtattc
    45061 cggcacgttc tagctcctgt ttcactccta catggacttt gacatcttct cgtgtcattt
    45121 ttaaaacgtg atgaatcgca tagtcgattt cttgccttgt gatttttttc ttcgtattga
    45181 tcatcacgac ttgcttttta tcatatgtgt ctaccaatag cagttgtgtt cgatctaacg
    45241 aaaataattt gtaataatta atagccgtat tcccaaaaaa gaattccact actttaggat
    45301 aaaatgtctt aatatttaaa ttactattca caggtgtttc gattagcttc atctcattcc
    45361 tcttttctat atagtcgatt tagatccaat cttaagttat gttaccatct ttcctagcat
    45421 taaggaatcg gttacaattg aacctttaaa gacaaaagga tttacctttt atcacttaat
    45481 agtataacat aatttcatga gaaaaaaata caattttttc ttgaccatct cgttacgtaa
    45541 aggattatgc ttacatttgt caggaggaaa aataatggag tacacaataa agaaaatgtc
    45601 agagatatca ggagtcagtc cgagaacctt gcgcttttat gatgagattg gactgctaaa
    45661 accagctagg atcaattctt caggttatcg gatttatggc aaaaaagaag tcgatcgtct
    45721 gcaacacatc ttattttatc gaacaatggc attcaagttg gatgatatcc aagaggtctt
    45781 agacaatcca tcttttgacc accagaaagc tttaatcaag catcagcaaa tgttgctgga
    45841 aaaacgggca caaatcgata ccctcttgac aactgtccaa cagacacttg atatgtacga
    45901 aggaggaaga aaaatgagtg acaaagaaaa atttgaaggg tttaaacaac aaaagttgaa
    45961 agaaaatgaa gaatcctatg gacaagagat tcgacaaaaa tacggaaaaa aaaaggttac
    46021 agcatccaat gaaaaatgga tgaatatgga taaagaaacg tatgaagaaa tgcaaactgt
    46081 tgaaaagcag atgttatttg atctcactct ttacttaaaa gaaccagaag atgaaagctt
    46141 agcagaccgt atcttccaag ctcataagaa gtggttatct tacagctggc ctgaatatca
    46201 gccaaaagcg cataaaggac taggaatgat gtacgaagcc gatgaacggt tcactgcata
    46261 ttatgacgag cgaagtggtc atggtgcagc aaaagcttta aatgaaatta tccaaaaaaa
    46321 ggcgtaatct tttacatgat ccaacaaaaa agtacacgta aaatgaccta ataacaaaac
    46381 agcagacacc caagttagat ttttatgcta acttttggtg tctgctccat tctttcacaa
    46441 gttttttcat cctactttaa atatattcat cgttgaataa acgtataagg tattttcact
    46501 ttatcctttt tttctgtaag aaacaattga aatgccattt ctccgcaagc ttccagatgg
    46561 tggtcgatgg ttgggaaacc aagaagctcg ctgatcagca aattatcgcg tccaatcacc
    46621 actggtgtct tatcttgcag atagctttgc aagatgcctg ctgcaaccat atccgaattt
    46681 gtaaagacac catcaactcc aagctcttta aaaaagaagc ctgcttgttt tcctttctct
    46741 gcatctatac aatcccaaaa aacaagtgat tcatcaaaag atggaaaaag ttgatgacat
    46801 agctgcaaag tgatttttga gttataactt agcctgccac ttcgccccaa cgtgatgccc
    46861 aattgcttta taccttgctg cttcaaataa gtaagacctt ctgtaattga ttgttctcga
    46921 tcaataaaga cacagcttgc ctgttttccc ttgatttctt cacaaaaaac tagaggtcca
    46981 tatttttgat atgccaataa atcatctagt gtattggcac gagacgtaat gatcaatcca
    47041 tcgaaagctt tagctgcaaa ttcttcaaga taccttcgct ctttttcttt ctgatagccc
    47101 gtcggtaaaa gtgtcacttt gtaatcataa tcaaacgctg cttcaatgat cccactgatc
    47161 aactgatcaa aatacggatg attggtataa ggcagaatca ctccaatgct tttcgttttt
    47221 ccataactta actgtctggc atttgcatta gggatataat cgacttcttt catgaccgca
    47281 agtatttctt tccttttttc ctcatctaca tatggatgtc cattgattac acgtgaaata
    47341 gtagaaactg aataacctgt gagctttgcg atatctcgaa tgtttgccac tgctgcttcg
    47401 ccacctatac aaaaagattt tcttgtaaat agtctaccac agctggaccg cattcaaaaa
    47461 actgatacat ttttccttca tgcgaaaaac tgatccgctg cccgccccaa tatatatctt
    47521 ttgtcaaatt ttcgatttca ttcattggta tttcttttac tatattccta ttcaaccctt
    47581 gaaaactgta caacgttaat acggatccct tgaactcgac aaacgcataa aaataattgt
    47641 tcgttgtgcc atctgttatc tctacataag tattcattgc aagccctcct tttgatactt
    47701 tgagtatagt gtatgaaacg cgtctcatag caaggagttt gttttgccaa agaaaagttt
    47761 tattcctctt tcattattac caaagtctct tattttaaat tgaatacatt ataatgatac
    47821 tgtaaatata tctttattat tagtgaatgg atatttactt ttaatagata aaatattata
    47881 actattaaaa ataactattt tcattataat tacacacaaa aaagagcgtg agacaaaagt
    47941 aaagaacact tttgtctcac gctctaaaca cgtataaaca gcggaagcag aagcaactcc
    48001 ttcggaaata agctgaaatt cacaaaaatt tgaaaagcaa tttccgtgaa tttcttctta
    48061 tttcttggag ttaaacgctt ctgttccagc ctctttttat ctgtctttca ctaatgatca
    48121 gttgtagata agcaagttgc tttttcttac atcataccgc ccatcattga tggatccatt
    48181 gcaggagctg ctggcgctgc tggttctggt ttatctgcaa cgactgcttc tgtcgttaat
    48241 aacaaggcag aaacggaagc ggcattttgc aaggcagaac gtgttacttt agttgggtct
    48301 acgatacctg cttcaaccat gtttacccat tctccagtag cagcattgaa accagtgcct
    48361 agttccacgt tcttcaattt atcaacaatc actgatcctt cataaccagc gttttcagcg
    48421 atttgacgaa ttggttcttc taaagcacga acaacgatct tgatacctgt tgccacgtct
    48481 ccttctgctt ctacagcaga aactttgctg ataacgttca ctagagctgt accaccacct
    48541 gagaccattc cttcttctac tgcggcacgt gtagcattca atgcatcttc aatgcgtaat
    48601 tttaattctt tcaattctgt ttcagtagct gcaccaactt taacaacagc tacaccacct
    48661 gctaatttag ctaagcgttc ttgtaatttt tcgcggtcaa aatcagaagt tgtttcagca
    48721 atttggtttt tgatcaattg cacacgagct tcgattgctt ctttttctcc agaaccttct
    48781 acgatcgttg tattgtcttt atctacaaca actttagaag catttcctaa gttttcgatt
    48841 gttgcatctt tcaattctaa acctagatcg tcagtaatta ctgtaccacc tgtcaaaata
    48901 gcgatatctt caagcattgc tttacgacga tcgccgaaac caggagcttt tacagctact
    48961 acgttgaatg ttccacggat tttgttcaat acaagagttg gcaatgcttc accatctaca
    49021 tcgtcagcaa taatcaacaa tggacgtgat tgttgcaaga tttgttctaa caatggcaga
    49081 atatcttgga tgttagagat ttttttgtct gtgatcaaga tatatgggtt ttctagaaca
    49141 gcttccattt tgtcgttatc tgttaccata tattgtgata agtaaccacg atcaaactgc
    49201 ataccttcta caacatctag ttctgtttcg atcccttttg attcttcgat tgtgatgaca
    49261 ccgtcgtttc caactttttc cattgcatca gcaatcaaat gtccaacttt atcagaaccc
    49321 gaagaaacag ctgctacttg tgcaatggct tcttttgaat caacaacagt tgagatatta
    49381 tgcaattctt cgactgctgc ttttgttgcc aattcgatcc cgcgacgaat gcctagagga
    49441 ttagcacctg cagttacgtt ttttaaacct tcgcgaacga ttgcttgtgt cagaacagtt
    49501 gctgtcgttg taccgtctcc tgcaatatca tttgtttttg atgctacttc tgatacaagt
    49561 tttgcaccca tgttttcaaa atgatcttct aattcgattt cttttgcgat cgtcacacca
    49621 tcatttgtga tcaatggaga gccgtaagat ttttctagta cgacatttcg gcctttaggt
    49681 cctaatgtta ctttcactgt atctgctaat ttatctaccc cgcgtaacat agctgcgcgt
    49741 gcgtcttctg caaatttcaa ttcttttgcc atgattgatt cacctcattg attatttttg
    49801 attatttttt tatcttccaa atttactcaa caatcgccat gatatctttt cctgcgacga
    49861 tcagatattc ttttccttcg tattttactt ctgtaccggc gtatttttcg aacataactt
    49921 ggtcgcctgc ttttacagcg gcaggaactt tttcaccgtt ttctaacaaa cggccttcac
    49981 cgactgcaac aactgtccca gtttggggtt tctctttagc agcagaagct aaaacgattc
    50041 ctccgacagt tttttcttct tcttttgcga cttcgataat gacgcgatca cctaatggtt
    50101 ttaacacgat aaatccctcc gataactctt tttttaatct gttagcactc ttaaccttcg
    50161 agtgctaacc tacattttta ataatactca ttctccctct tttttgcaag cttttaaatc
    50221 aaagaaaaga aattttattc tgacagctgc ttattgaaat tatgatataa ttgaaatcaa
    50281 tcgatataag cttgccttgc atgcttgtta tcccttaaaa ggaggaatta catgtcttta
    50341 aaaaaatata gcttcctcag cattttttgc tatggtctaa tttttatctc acccttgatc
    50401 ctagcttcga taggacttgt aaaatctacg tctgaattga tcacagcaac tgcagtcatg
    50461 tatatactag gcgccgttgt cctagctatt ttttatttta agcaacgtga acccttagcg
    50521 atcgaatcag cggtaaaaaa agcttctgct ccaaagattg ttatttatgg attggttgga
    50581 atctttgtcg cattgattct gcaaagcatc gctgtcatgt tagaatctgt attgtttggc
    50641 aaagcaaccc cttccgagaa tacacaaaat atcatccaga tgatcatgga agcacccgct
    50701 tttattttgg cgacaactgt tgctggaccc atcatggaag agttcgtatt ccgccgcagt
    50761 atactgggga tcatcagtcg atattcaaat ttttgggtcg gagcagtgat cagctctttg
    50821 ctgtttgcgt ttgctcataa tgatggtcat ctgctaatct actttttcct aggtttcttc
    50881 ttcagcctag agtacaaagc aactggtcgg atctggacat cgatgatcac acacgtagga
    50941 atgaacacat tagttgttct tgttcaatta gctgtccaaa aagggctagt ataaacatga
    51001 ctataaatac tcctgtcatc ctagattggt gattttccca atctaaagcg acaggagtat
    51061 ttttgttttt tagtcgttca tcttttctgc tgctccatca ttttttgtct gtctttcctt
    51121 tttgcagttt gcagaatcta tttttttcaa aaatgggaaa taaatgaaaa aactaattga
    51181 caacacgata ccttgtaaaa tcgctgcagg cactccgcct actaagaaac ccgagaggat
    51241 cggcggtgtt gtccaaggga cttggactgc tgtaaataaa ggaacgaatc caaaatataa
    51301 agcggaatag gtaatcaatc ctgaaacgac cggtgcgaaa ataaaaggaa cagccatcat
    51361 cgggttcatc acgatcggtg tggaaaaaat aattgattca ttgatgttga aaaaggctgg
    51421 taaaagagca agatttccta attctctgta tttcttcgat ttcgcaaaaa ccgtcataaa
    51481 aaatacagcc cctaacgtca atccagcacc cgtaaccgtc atgaactgat cgagaaattg
    51541 ctgagtaacg atatgtccgc catttgccac cgtcaactct tgtcctgagg ctaagatttc
    51601 tgcatttgct aatgaattcg cttgcaagac gggactaacc aacccattga ccatcgcaga
    51661 tccatgaaga ccaaataacc ataaaaacgg aacaaaaaaa cctaataaaa gcacaccaaa
    51721 caacgtgtct atgaacgatt gaatgggaag ctggacatat gtccatactc cttgaacaac
    51781 agtcattctg aacaaatgtt gaaaaaccgc tgaaccgata agcgtaaaag tgactataac
    51841 aatgattgga atcaatgaag taaaagactg ccaaacattt tcaggtatct tctctctttg
    51901 cttccaccct ttcgcaagtc ttactaaacg tgcatagccc catccgatga tgagcccagt
    51961 tgtaactgct cctagtatcc cttcagcacc tgtccagaca gtatctatct gagtatttag
    52021 tggctgaata agcagtagat aagcagacaa ggctgttatg ccgactggta agcgatcgat
    52081 gtcttcttct tttgcataag cgtatgcaat ggcaaaaacg atccaaaagg ctatcacatc
    52141 aaatgtagcc tggtatactt gtgtaaaata catagaaaat cctgttttgt ctatccactg
    52201 agcgatgtaa tccacaggaa aatgagcaaa taagaaaaac agcgagccaa caataattat
    52261 tgggatcgtg taagtcattc cattacgcaa agcagttaag ggtctaagat tcacaacaga
    52321 tgttatcatt ggtaaaaagg cacgatctaa ccactctttc atttcttatc tccttcaact
    52381 tctattttta tcaatcagtt ttcttaattt aactataccc aatgatcacg aaccatgaaa
    52441 ggaatgcgca ctgagctttt caaaaatcgg attctttgac gaatattcag caactgctta
    52501 caatggacag gaataaaaaa ggaggttttt tatgaaaatt gcactcattg gagctactgg
    52561 ccatgcaggt tcatttattt tagacgaagc attgtccaga gatttagacg tgacggcaat
    52621 cgtgcgtcat ccagaaaaat tgccatcaga tgttccgttt atacaaaagg atttatttga
    52681 gttgacaact actgatcttg catcttttga tgttgtcgtt gatgctttca acgctcccaa
    52741 aggaaaagaa gaaatgcatc aaacttcttt gtcccatttg attgagatgc ttgaaggaac
    52801 cgatacacgc ttaattgtcg ttgggggtgc ctcttcgtta ttcttagata cagaaaagac
    52861 gactcgtatg attgaccaag tacctaaaaa tgcacccttc tatccaacag ctttcaatat
    52921 gtacgaagga ttgttaaaat tgaaacaatc taaaaatcta cattggactt atatcagtcc
    52981 agcttcttta tttgatccac atggcaaacg tacaggtact tatttgttaa gtgatgatta
    53041 tttacaaaga aacgctgcta gcgacagtac gatcagcatg gcagattacg cgattgcatt
    53101 agtagatgag atactggatg agaaacatga aaagcagcac atcagtgtag tcagtcgata
    53161 atacggttat ttttttaata tgctaaaaaa ataaaaatag aagataaaac caaccctgat
    53221 tgattttatc ttctgctttt tatattttta ttgattgaac tgtttaaatc gaaaatagct
    53281 cagttgcttc atctggatct gtatcataga tttcaaaatc atgtccaacg ccaaaatctt
    53341 tttctttcaa aacattttcc attgttaaat gagcaagttc tttcatattg ttttccttgc
    53401 taagatggcc aagatagatt cgtttggtcc gattaccgat cacatcagtc atgacaagtg
    53461 caccgtcttc gttggaaaga tgtcctctat ctcctaaaat acgctgtttt aaattccacg
    53521 gataaggtcc catgcgtaac atctcaagat catgattact ttccatcaaa taaccatcgg
    53581 cattttcaat gacacctcgc atataatcac tgcaatatcc ggtgtccgtc aacatgacga
    53641 atgaccgatt ttctttatgg aaacgataaa attgcggagc cgctgcgtca tgggagacgc
    53701 cgaaactctc aatatcgata tcgccgaatg ttctgacttt ccccatctca aatagatgtt
    53761 tttgttccac tggtacattt ccaatcagtg gttccatcgc ttcccaagtc tgctgattgg
    53821 caaaaacatc caaatgatac ttacgagcca agacacccac gccatgtata tgatctcgat
    53881 gttcatgcgt cacaagtatt ccatctaatt ggtccggtgt ccgatcaatt tgagccatca
    53941 aggaagtgat ttttttaccg ctaagtcctg catcgaccaa aagccgtttt ttttcacttt
    54001 cgatataaag tgaattaccc gaacttccac ttgctaggat actgatttta aaagctggtt
    54061 tttcttcagc catttgactc ctacttccct tcttactttg taaacttttt tcattatact
    54121 cgctttttta ttgatcttcc acttttggta cagtattgtt tgtcacgatc gtattgctga
    54181 aagcgttgac gctctcaatt tggaccactt tatcgcttgt ttcgatcgct acatgccaaa
    54241 caggaacata cacatttttt tcccggactt tcagaataca ggaataagct agctgacgcc
    54301 ataaaatttt tgatcctctt ggtattttgt tattgatgta caatgtattg attgcttcct
    54361 cttccgtata cagttccgtc ttttcgcgca gctgctcgat atcagataaa tgcgtctgca
    54421 tgtatttcgt gatgctataa tcattatcgt ttttttctaa agaaagaacg atttttgctg
    54481 tatcatcatt gaatgggatg ccttcatact cttggcttgc ttggatttct agtggttctt
    54541 cttctaaatg agaaaagttt ttcgtgtaca cataatcatt accgaataaa atattgtctt
    54601 tgttagataa aaaatcttcc aaggaactac taattttatc tggatcgatc acgttctttt
    54661 cagcatctga actggataaa gatttcgtca aaacatcacc gtctaaaaac acaccacttg
    54721 ccagcaagcc gcttttacca gccttgcgat aattcgctaa tgaagtgcta agattggtct
    54781 gctccgcgct aagataatag ccttgcttgt tctcagacga aatcttcccc gtgtaagtga
    54841 tatcgtcgct agccagacgt tgttggattg attcagtctg attagagcga atgacattgt
    54901 tttcttggta taccgcgtca tgataactgc tgaataaaaa cacattcaac cctaaaaaag
    54961 cgacgaaaaa tatccattcg atttttttga aatccaatta attcgcctcc aatccaggta
    55021 atttttccag aaggtcgtta gctgaatacc agttatcttt atatttcaca taccattcag
    55081 gtaagagatc aacgacacga ttcgtttctt tgacattttg ccatgtatag ccaacgatca
    55141 ctgaaccaat cttgttgcta tctgctccct tagcttttaa ctgctggatg atttcattcg
    55201 tacttgcaag ttctacttct tcgtctgaag gtatcggcac ttgaatcgta ttcaaactgg
    55261 tttggatatt cacttgcaca gaaccattcg tttcaccgcc aacttccaca ccaatctgtc
    55321 ctctgctgtc tgtcccaaaa accgggaagc cttccacgaa tatccgataa tcgatcgtat
    55381 tgtcactgcg gtcaaaatat ctgaggttcc ctaaagaact gcctaatttg ctaatatagg
    55441 ggaaactttc agaaaataca ctagcatttt cttttttctc tggcagctct ccacgaaaat
    55501 caactacttg cgtttccgaa tggatagaca ttgtttcatt cccaccgtaa aaaatcaatt
    55561 cattgctttc atcattattt ttcacgctat ctggtttctg gaaaaaagca tttctaaaaa
    55621 gtgtataggg ttgctgtgac aggatataac tatacttctt cagtttgatc gaatgtttcg
    55681 tagcatattg cgtgtcgatc gtcgatggtt ctgttgtcat ttctgtccat tttgtgtctt
    55741 ttgctgttaa ttctttattg atatctgtcc aattcaacga aatatttgct tcatatacga
    55801 gatggttcga ataattcaaa aatcggattt ttttatttcc ttgatcgaat tgtattctag
    55861 taaaatacat attttcgctt tcttttgcca agttcgacac atctaaatct aaatcaaatg
    55921 cttccttgta ttctcttagc aaaaaaggcg cattataggc caactcaaaa ccagagttca
    55981 gatttttcac ctgttcaaac tgtgatttgt ctcctgaaac tacttcagaa agctttccaa
    56041 atcttgcttt atcgatgatc aattgcaatc ggtacacgag attttcactg ttggtttctt
    56101 ggatcattcc cgaatggtgc catgtaacat gaagcggaag aaagacttcg gaagtttttc
    56161 gattgctttg agactcgatc atttgagtgt ttgtctcatc tacgttgatt gaactttttc
    56221 ctgctgggct cagccagatt gcataagaga agtatatgct taacgcaacc atcaaaatga
    56281 gtcctatacg aacgactttt tcagagattc tcattcccac cattcctcct cataaggttc
    56341 atatggcagc gagatataaa aagtcgaccc ttttccttcc ttgctctctg cccaaatagc
    56401 gcctcgatgc gccttaatca cttctctaga aatagctaat ccaagtcctg tcccaccttg
    56461 tgctcttgca cgtgctttat ctactcgata gaaccgctcg aacactcggt tcagatcttt
    56521 tttaggaatc cccaatcctt gatcggtgat acttaaaatc acgttattat gcgtttctaa
    56581 taagcgacaa gtaatcgttc ccccatctgg tgaatacttg atcgcgttat tcatgatatt
    56641 atcgactact tggatgattt tatctgtatc tacttcgacc caaagatctc tttgcgtaaa
    56701 ttcacgacgg atcttataat ttttttcctg atttcccacc atcatatcaa accggtcaag
    56761 aacaaaattc actaactcgt tgaaattgac atattctaat tgaagctggg tattacctgt
    56821 atccatgcga gatagattta agaggtcatt gatcattcga atcattcggt ctgtttcatc
    56881 tagcgttacc ttcaaaaaat ttggtgctac ttcctcgtct ttccacgcac cttcgctcaa
    56941 tgcttcgata taactacgca tacttgtcaa cggtgtacga agttcatggg aaacattaga
    57001 gacgaattca cgacgttccc gttctgtttt ttcttgttct gtcacatcat gcaagacagc
    57061 tactaatccg ctgataaaac ctgattcgcg acggatcata gaaaagtcta ctcgcaagat
    57121 catctgatca ctttccaatg tactggttga acggtcaagt accatttcgt ttggatcttc
    57181 taataatttc cgcaacgtat attcttcttc gatatctaaa agtgtcaaaa tcgattgtcc
    57241 gattgcttcc tcgtttttga tatctagcaa ggaaacagcc atatcattga tcgtaatgac
    57301 tttacccctg cgatctgtcg caatgacgcc gtctgtcata tgggatagca cgctatccaa
    57361 acgattgcgt tcagcttcca ttgtatcttg agcttcttca atacgttcag ctaactgatt
    57421 gaaggtatca gccagctgtc caagttcatc ttgtccatgc actttgactt tccgactgta
    57481 gtctcctcta gcgattcgaa tggcttgttc tctcatttca ccgatcggct gtgtaatcga
    57541 acgagcaact aaaacagata cgatcattga aataaatgcc gcaattagtg aggcagtaaa
    57601 gaaaatgact gctgtgttat tgatttccga atatttttgt tcgatattac ttttgacgta
    57661 aagagccccg ataacggcat cgccggtcgg ggacaggatc ggttgaacat tgatattcac
    57721 ccgtttatcg tcgttatcta aagcaacata acgtttagtc gtgaaatcat tgatatcaac
    57781 ataatcattt ttctttccca cagcgctttg ttcattgaca tcggttgttc ctcggatgat
    57841 ccctttttcg tcaacgaccc gtatttcgat gatatcgcta gtcgcactgt tttcaataaa
    57901 tcttttgata ttcgcattta cctcttcatc atctgcatta tcttttcgat tcaattccgg
    57961 gctgattgtt gttgctaatg attccaccgt ttgattcata tctttaataa atgtattgat
    58021 cgtggaacgt tctaaaccac gtataaagta ggcaccaata atttcgatcg agatcaataa
    58081 aatcagaata aaggtaatag cgatcttaaa attgactgat cgaaaaaagc ggacttttct
    58141 tttcatccaa ttactcctgt tctgggttac gcaaatagta accgacacca cgacgtgtca
    58201 ctaaataatt tggatggctt ggattatctt cgatcttttc acgcaaacga cgtacagtta
    58261 catccactgt tcgtacatct ccaaaataat cataacccca aaccgtttgt aataaatgtt
    58321 ctcttgtcat cacttgtcca aggtgcttcg ccaagtaaaa gagtagttcg aattcacgat
    58381 gtgttaactc gattgtttct cctcgtttcg tcaccatgta agcttctgga tggatcgtca
    58441 aatcaccaat cgtcaattcc gcaggtgctg cctcttctgg ttccttcgca gccgtggcac
    58501 cgcgacgaag atttgctttg acacgtgcaa ctaattctcg gttggaaaat ggcttggtca
    58561 cgtaatcatc ggcgcctaac tctaagccta ggactttatc aatttcagaa tctttggctg
    58621 ttaccataat gatcggcata tcataagttt tgcgtacctc acgagcaact tctaagccgt
    58681 ccattttagg tagcatcaaa tcaagtaaaa tcaaatcagg ttctacctca gcaacttttt
    58741 ccaaggcttc ttccccatca tatgcagtat aaacgtcata gccttctttg gctaaattga
    58801 atttgacgat atccgaaatc ggcttctcat catcgacaac taaaactttt ttcataaaga
    58861 gccacctctt atatattatt gtcatacctt ctcattatac cgtatttctg cttttgtttc
    58921 atctttgcct ataaaacaaa agagaaaatt aaaatgaaag tgcaaaatac tttattattt
    58981 tttgttctaa cttcaataaa aaaggaaaac actgattttc acctcagtgt ttcctttttt
    59041 tgatttatcc ttctaaaact tgtacaccga cacccaataa tcccggacca gtgtggacta
    59101 ctaatgccgg agaaatctgg ccaaagtaga tttggtttgc ttgtgggaac tctcttttaa
    59161 gtctcgcttc catttcaatt gcttcttctt tcgcatcccc atgggcaaca gctaagttga
    59221 agacctttgc attaccgatt ttttctttga cgtaagcaac cgttttatcc aaactttttt
    59281 tacgtcccct agcttttcct actgtgtaat aaatcccttc ttcattacat gagatgattg
    59341 ggttaagctt taaagcggtt cctacaatag aagcaactaa accgatccgt ccaccttttt
    59401 gaagatattc caatgtcgca acattaaaga aaacttttgt tctttcgact aactcattca
    59461 gattactgat cagttgatcc cattctactc cttcttccag ccattttgct gcttggatcg
    59521 cagaaaaacc tgcaccaata ccaatatttt tcgtatctag tacatatgct tccaattctt
    59581 cttgctgttg tgcaattaaa cgaaccacat tatatgtccc gctcaatcca ctggaaattg
    59641 ttaccgcaag taccttttca taaccgtctt ttttgatttg ctcaaagatt tctgtgatcg
    59701 actcaccatc cggcaaagat gtaccaggga tttcctctgg caaacgttga tagatctctt
    59761 caggggtaat gtcaatttta tctgtatata cctgatcttt ataaataatt ttcaatggga
    59821 tcatatacat ctcgtatttt tttatcaatt cttctggaac atccgtacct gaatctacta
    59881 aaattgcgat tttattgttt ttcatttgtt ttctcctctt ttaaatattc ggtttctaga
    59941 acaatcgttt tttccgcaag aagtttcatt gcaaacgata aagttgccgc tcttacagca
    60001 atatattcta caggggttgc ctggtcgaat ttttgcggat gagatttacc ttgtgctaat
    60061 tggctgacca tccacacagc tgcttcttgt tcatcgcaaa atagattata ggcttcacga
    60121 attcctactg tttttccttg gaacaatatc ccttctttga tttcaggaat agtcaatact
    60181 tgtttcaacg tagtgattgc aagtaaaaat gctacgtgtt ctttgttata tcttttttta
    60241 actggtgctg gtatcaaacc tagtttaacg taattgttta ccatagaaga ggtaagcaat
    60301 ggatgctttt ctccttgtat cacaggtgaa agataacgat caactaacgt tctgacttgg
    60361 tccatataaa gttctaagtc agggagttct tcccagtgag gcagacggaa tgtttctagt
    60421 tccttccccc actccattaa ttgctgacgc attttttcca tcataaccgc tccttttttc
    60481 atttcataaa catgatatca gacttatgat aaacattcaa tctagttgct ttaactaggt
    60541 gatttgatta gcgggattcc atgaaaacaa aaaacaagaa ggctaagcct tcttgtcttt
    60601 tatcgttaag aacaggagac ccgccgggga gacggcggga aaggagtaaa aaatgaaaaa
    60661 agtgttaggg tttgttctct tgcaagaact ttgtttgttg gtatgcttat ataatagcga
    60721 gcaaatgtga ataatctatg aatgatttcc tataaggaag taaagatttt tctgattttc
    60781 tttaaatgta gtcttgcatt ttaaaattct tagtgctact attattaagt actttttgta
    60841 cgggccgtta gctcagttgg tagagcagct gactcttaat cagcgggtcg cgggttcgag
    60901 cccctcacgg cccattgggt gccaaaccca cggaacaggt aaatgttggt gcgaaagcat
    60961 ttcgaaaaca tttacgctgt tcttttttta tttttcaaaa taactagggc tttttatttt
    61021 taactcaaag tccactgtag ccctttggac tttgagttaa aaaagaagca taattatgaa
    61081 cagtaaagtt tctaatataa caataattcg agaagctttg caaaatcatg ctgccaatga
    61141 actctctaaa catataggat taaatctaag tactataaaa ggttaaaaag tgaagaatat
    61201 ttaatagaaa aactaaattt acttgctgct ttcccctttt ccattaatac aacaatcaga
    61261 gagtgtcttt ttttcgaaaa aattagaata aataaaagac acgtagtttt tttatctaca
    61321 tgtcttccat cgactacaag ttatcatttc tcaaaacgta tttagctttt aattgattaa
    61381 tcgtttcacg ttgtctacac attgcctaat taagattttc ttattagaag catcaatccc
    61441 gcaataatac ctaaaactcc aggaattacc cacaataatg ttaaaagaaa aaatggaata
    61501 atagataaaa tgagtaaact aataccatag accactgttt tttgattttt tcttactaaa
    61561 aaacctatta tgaaaatcat tatcgaaaaa actagggtaa ttcctccaaa taaaacaaca
    61621 ttcccgctta gattgactaa catatctata tccttactgg ttagttctgt agtatttaaa
    61681 gtagttgaat caatagaaga tagaaacata ccacccatca atgctaaaag actacataaa
    61741 atccctgtta ttccactaat taaaatcaaa ataaactctg tttttctctt attcatttaa
    61801 ttctctccag attaagtgtt ttagaattag aaattttttg accatagtta atagcttcta
    61861 atgaacgaat aacaaccact gacgtgttag aaaaataatc cccaatatgt tgtttcttgg
    61921 gcgtgaaagc agccaccaaa tacccaattt gaaatacaaa attttttaat ataaacctac
    61981 atatacactc acgaataaag atagtttgcc aacttagctc tttttcctca aagctcacta
    62041 ctcttatccc aaaaatcatt ttcccaattg tttgtcctga attcagctta gtcaaaagta
    62101 caaaataggt taaataaata gctaatgacg ctataccata aaaagtaata atggatttgt
    62161 cagattccag tcccatgatt ttgtaaaaga gacctatagt agcatgggtg atgatgctaa
    62221 tacaaattaa atcaataaga aaagcaaaaa atcgtaacca aaatcccgca aatacataat
    62281 taggcaaagt ttcaatgcca ctcttcttat tcattttata gccctccata gtaatacatt
    62341 ggttttggag tatcagaaaa tccaagtttt tcaaaaactg aaattacacg atctgatgta
    62401 gttgccttta gcccttgcca ttcagcaatc ttattaccta accaagaaga agcaaagcca
    62461 gttgtgtcat ttttatattc tataaccgtc gcatcagtta atttcttctc tttttttagg
    62521 gaatctaatg catcttcaga gtaaccaatt tgatccacca acccattttc tactgcttgg
    62581 ttaccatcat aaattcttcc atccgcaagt tctttcactg cattagtatc catatttctt
    62641 ccttttgcta caacattgac aaaacgatca taagcactca tcacaaattc ctgtataact
    62701 ttattctctt cctctgaagg tttgtgttga ggtgacatca tatcttttaa tgcaccactt
    62761 ttatacgtcg catcagttac gccaagtttt tctaataagc cagaataatt taaaccagaa
    62821 ataatgacac caattgatcc agttgttgtt tcttccgtag caaatatttt atctgaacca
    62881 gcagaaatgt agtaccctcc acttgccgct gtatttttaa atgcagtata gataggaata
    62941 tctagctttt taatttttgc catttcttta gcaatctcag cactttcata tattcctccc
    63001 ccaggtgaat ttacttctaa taacactccc ttaaccgctt tgtcttcttg aattttcttt
    63061 agctgtgtta aaaaattctg atggttatat tgttccctac taaaaagatt gctttcacct
    63121 gtatctgcaa taactccatt gacggatagt ttgacaatct ttttatttga tgcgccttct
    63181 tctaacgttt cttctgtgat ttcgttagat ccgtaaaaaa tcttatttat tcctgttagg
    63241 gttgtatttg atgcttcctc tttatctttt cctggaatta gcgcgacgat aatggatagt
    63301 aacaataatc cgcacgctac tcccacagca atccatcttc ttttattcat ataaactcct
    63361 cctatattct tagtaaaaat aattattttt tatttagaaa cacatcgaca atttgttgcc
    63421 aatatgtttt ttctcctaca attaaagaca actctccagt taatccataa cgaaacggaa
    63481 acgattgagt tgtttttaac gttcctttca ctgcataaaa aacacctttc tcagtggcag
    63541 tagaattttc tgaaatttca tctaaagttc cgtcgatcgt aatcggagcc ccaccttttt
    63601 gatccaattt aaaatgaacc ttcatccctt ctttaatata ggtactttca ttcgcaggta
    63661 aaagtgctgt aaatttcatt tttgattttt cgtggatcgg ataaatttct gcaagcactg
    63721 ttcctttggc tagttctgct tgtccctttg tttcttcatt taaatgaacc gttccagata
    63781 caggagcttt tagtattcct tttgaaagtt gatcgtccaa acttttgata actgactggt
    63841 tcttctcttg tttttcattt agctctgtaa ctgtttgttt tacagttgtt attgcttgtt
    63901 ctagctcttg ctttcctttt tccgtttgac taattctgtc attctcagaa gtagttggtt
    63961 taactaattt agctttttct gactgatact gttctacttc tttttttagt tgctcaattt
    64021 gttcatttat gcttgctgaa attgtcagtt tcacttgatt tttttgatca tcagaaacat
    64081 tatttagttg ttcttgccaa ttctcatagt ttgccatcat ttcttttgaa aaatctttta
    64141 atgattgatt attactccaa gctacctgta cttgttgcca ttcttgtaat ttactatctg
    64201 aactctcaat ttgtttttct agttgtcttt ttgtcttttc gtatacttct aattgctttt
    64261 gatcatttaa ttcactttgc ttcaaagcgt agcggagtga ttctttttct gacaacatgc
    64321 tctttaattg attactgtag ccaaaactgt catccgttga aaacaaattt tttcctttac
    64381 ttatactttc aataaatagc tgagccatct ttatttgttg agtaatacgt tggttttctt
    64441 gttctatctg agccttttca ttctctatta aagaacaatc caatctaacc aacacatcgt
    64501 ccttatgaac aaattgattt tcttttagga agttttccat tattttagct tctaatggca
    64561 cttgtaactt ctctattttt tcggggttca attgagccgt tgtccgaata acaacctctt
    64621 ttttagcaaa ggttaaaaac aatccaataa tacataaaaa aagaattaca gggtataaca
    64681 cccaacggta gaagctatga tgttgtttag tatagatact agaatgttcg aaccaattat
    64741 tattctgcat aaattgtttc cctctcctag atttcccata atttttgata gataccatcg
    64801 gcaaaacgaa gttcatcgtg cgttcctttt tctaccaaat gcccttcatg gagaactaaa
    64861 atttgatcac atgcttttgc tattggtaaa tgatgcgcaa taaaaataat cgttttttct
    64921 tttaaattga ggagataatt cataattgca tgttctaaca aggtatctaa tccactagtt
    64981 gcttcatcta aaattaatat gtccggattt tttaataaag cccgtgctaa ggctaatcgt
    65041 tgtcgttgcc ctcctgaaag attatttcca ccttcttcca acaatgtctc gtaacgtaat
    65101 ggctgttgat taataaattc atttagttgg actatctcac aaacttctat tatttgttcg
    65161 aaacttggtg ggctatctaa accgaatata agattctcaa tgattgttcc actaaagaaa
    65221 aatgactctt gaggcaaata tgtcactcga tcgcgtaata tctgaaaagg aatgtctaag
    65281 tgattaatgt ttccataatg gatcgatcct tctgatgctt cataaaaacg aacaaataac
    65341 tttgcaagag ttgattttcc agaaccacta actccaacta tagccgtttt actgtgcgaa
    65401 ggaattgtac atgaaatttc gttcaacgtt ggggccttca tgctatacga gaatgaaacg
    65461 ttttttacag tgatatcttg ttgaaataat tgttcagaaa gcatatattc aaaagactgg
    65521 ttcgattttt ctgaatcaat cgcgaaaatt tcatttaaac gattatttgc aacttgagcc
    65581 gtttgcattt tcacttgtaa attaataatg ttttgtaaag gatctgtcaa aaatactagt
    65641 aaagcattgt atgtgataag ttgacctaga ctaattctat tatccataac aaaataagaa
    65701 cctagccata aaattaatgc actgctaatt aattgaatca aatgtttaat tccttgttga
    65761 atattatcaa gcgtaaccgt acgaaatgat tttttcatta atttaacaaa ttcatggtct
    65821 atacggttat atactttctc ttcaccgcta tatgctttaa ttgtttctat tcctttaaga
    65881 ctttctatga tactagaatt tacagctgca ccggctgcca tttcttccct gttcgatttt
    65941 tcatagcttt tcacgaaagc gaatattgca actacataaa aaggcaaaga gcatagagtg
    66001 attaaaaaca acgtactatt ctgaatagct aacgtaaccc caacaagcaa caccatacca
    66061 atatctaaaa atattgataa cgtagcactt gctaaagcat caataatctt actggcatca
    66121 agaaaacgag aaataatttc ccctgatttt ctcgtagcaa aaaaattcat tggtaaagtt
    66181 aacacatgtt tgaaatactg aagcataatt gccatactca ttcgctgtcc taaaataata
    66241 agaagataac tacgactata ttcaaacaat acccgaaata aatagacagc gatcaagcca
    66301 atggaaatta tatttaaagt tgaacgtgct tgattaggga tgaaaaaatc aagaatacct
    66361 tgaaaataat atgagcttcc tatgccaaaa aacgtaatga aaatcgatgc taaaacgatg
    66421 tggaatacta atcctttttg tttccaaatt ataggcaaaa aagaacttaa tccagctact
    66481 ttttctttaa taggaatata agtttctcta ggcataggta ataaaagaat acctgtccat
    66541 tctttttgaa acgcttcaat cgtttttcta ttttttccat tagcgggatc tgcaatccat
    66601 agtacgtttc ccttcgtttt ataaattaca acgtagtgca tatagctgtt atcaaccaat
    66661 atatgtgcaa ttaatggtaa gataagatct ctttctttcc agatctcact atctgcttga
    66721 atagccatac aatcaaaaga caatttttca aatgtctttt tcaatccaaa tgctgaagta
    66781 ccctctaaat cagtcccaga taggtcccgt aatttatgaa tcgggatatc agttttaaaa
    66841 tattttaaaa tcatcgaaag gcaagcaaca ccacaatctt tttcatcttg ttgctgcaca
    66901 aaaggaaatg attttatcac ttatctaaca caactccttc taaaaaattt ttatagaaaa
    66961 attctcaata tagctttaat acagtgaaaa tattgtctca taattccaca aaaactttga
    67021 aaacagttct tgaacactaa ctttttcatt cctgaatcaa atttattttg gaaattttac
    67081 tattcaagaa taaacttgat aagtttcagg aagattttta ctgttaatca aatacgtatg
    67141 ttacagtagc accgtaaaaa atattattta aagaagcgtg tttaaacatg caaaatgtaa
    67201 aggaactaag tattgtggaa atgcacaaac tgttggtgga ggcaataatg cttggggaaa
    67261 attggggcaa gttgtaggtg gacttaccac aggggcagta ggtggtgcag gtttaggaac
    67321 agcaatttgc ggaccagctt gcggtgttgt tggagggtta tatggagctg tcgctggagg
    67381 tgctgcagct ggctgggatg ctcgaaaaaa ataaaaaagg agaataagta gtatgcatat
    67441 taaaaacaca aaaacaacat ttatattatc ttcagaagag ttgaaaaata ttcaaggtgg
    67501 gagtgccgtg ggagttttag gcactacttt ttctggggca acagcaggag taaaactttg
    67561 ttcagccgga ggaccttatg caatagctgc ttgtggtgta ggtggagctt tattaggtgc
    67621 tggattcagc atgtggaccg gtgcgtaaac aattaaaaaa tatcaaacct caagattggt
    67681 ttgtgtcgat tacgaacata ggtatgttct ttatcttttc aaaagtttgg aatggacaga
    67741 actttttact aaagcttctt gtgctagttt ttataattat attaaatttt tatcttttat
    67801 taaagtcaga taaaaattct ttggaaatgt aatggtagag atatttttac aaaaggactt
    67861 gcagcgctgt agttggtgct gcaggaggac ctatttcggc cgttacagga ggtattggta
    67921 atgtacttgt cggatgtgca ttaaagcctg ttcctgcaag ttaaatttat aaaaacagga
    67981 aagtaattat ctcaaatcct atcaagtaca atcataggat tgcacttgac aggacaaatt
    68041 ttttaactaa aaaatgaaaa acactttcta aaaattagta gaatttgcca aatctttcgc
    68101 atcttccacc atacatttaa ttttaattcc cctttatggt acttaataaa aacaagaaaa
    68161 gaactattca tttggccctt ttttggttcc agaccataga aatattcctc cagtaactaa
    68221 tattgctgtt atgcacgtaa ctaataacag ctataaaaat tggtacaact ttaataggat
    68281 tcagaaaaat ttgcactagt gaaggaatct attttattag aaaaatgcaa tctccctaaa
    68341 gaaaaaacca ctaaacagtg ctttctttca acttctcctt aattttttgt gctttcccta
    68401 aagtaaagtt tctggccaac tctgaatcaa aatatagtga acgtttttta aaatctattt
    68461 ctttaacgtt aaagatattt actaaacacg ctcgactaat tcttgttaac ataggatatt
    68521 tcttttcaag ctcactaatt cttccataaa attcgtactg cccatcttta gtacacaatg
    68581 ataatctatg tggtaatttt gaagcttcta caaaataaat gtcatttata tcaaaagtaa
    68641 atgtttgaga acctatggaa aaaacaaatg cttgattcgt aacctgtttt gttgcatcta
    68701 tcctttcttg cgctaataac aataactcaa caatctcgtt tcgatactca tctagtgttt
    68761 gatcttttgt tacaaatcct aacgtttcaa ctcttctttt tattgttacg ggtaacatct
    68821 catcatgagt agttgtaaaa atgatttttg cttgaacatc atattttctg attacttctg
    68881 ctaattctat accgttaact tcatgattta aatcaatatc taagaaatat attccttgct
    68941 ttggtcggaa ttgtttgagg tattttttaa cttctaacgg actttgtgtt ttcaatacta
    69001 tcttaaatac tttatcgtga aaaagaatga aattatcaat aattcgttct aactgattta
    69061 attgtataat ttgatcttca cataatatta ttggataact cataaatcct ccttccctca
    69121 aaacaacaaa ataacttgag tagtaaattg atacggatcg ttttgatagt tcacaaacat
    69181 attgggattc tttttattga tttcctctat actagataaa cctaaccctt gatgtccctt
    69241 ttttgttgtt attccttttt tcattagagt atctatagag agtagtatct ctctacaact
    69301 attcgatatc gaaatttcta tctgtttatc atctcggtaa atagctagag acagttctct
    69361 atcttgactc tctatagatg cttcaattgc attatcgaga ataattccaa gcaccctaat
    69421 acagtcaaat attggaacag gaacttcaat aatagtactt ggacattcga atttacaaca
    69481 aatcttattg ttatttgctt ggtatagctt cgctatcaac aaacttttca aatattcatt
    69541 ttttatattt tttaaataac gatattcaaa cttattggtt agataagaat tagaatagat
    69601 ctctaattct tttatttctt tttccaatat cgaatcatgg ttttgattag cgatttcttt
    69661 taaactcagc aataaatttt tatagtcatg tctaaatctg gcaaattttt cttgatcttt
    69721 ttccagtgaa tcagtatatt tttttagata aaccaattct tttcttttca attgctgttc
    69781 atattgttct cgttgcctaa tagttattct aataaataaa aatagaacaa caaacatttg
    69841 aatgattaaa aatattaaga caccaaacac aaaatgatca aatacttgat attgatgagc
    69901 aacataagaa acaaataaac caattgtaag taaataaatc atgaatatag cagtaagttt
    69961 agaactggac tgttcaacaa tcctatttat agctaatttt ctatataacc aaataaacat
    70021 cagcaaaaac aaagaatcaa gcattatctg gaatactaca taaccatacc cttttatccc
    70081 ttcaaatgaa aacatatacg tcataaccat ggaagtaata atagatctga aatcatcaat
    70141 aagcatacat aatagtaatt tatttaaaag cactatatta gttttcttct tttcctttaa
    70201 tataaaataa cttccgatta taggtatagc tgcggaaaca tcagtaaata attcaacaaa
    70261 aaaagtgagt ggtatcaata aacatacaaa aagatatttt cttttgttaa gatcagtatt
    70321 agtcatataa aataagagaa aaaagaaaaa gtttcccacg aacattctta atagataagc
    70381 ttttgtatcg atagtaatca agagatcccc tcctgatttt aggatatcat aaaaaaaatt
    70441 ttagttacac tttttaaata atgaaaaaac acattccact aaatttgatg ccggttttcc
    70501 ttgaggtttt gttccagcac ctcctttaat ttttttaagc tcttgatctg aacattgttt
    70561 agcatttagt ctattttttt cttccattac gattccccct acaaactata aatactttta
    70621 tgtcactgat tcaatatacc tatttttcta atcaaaaaat tttgagacat atttaatatt
    70681 ataagtatca ttaaaattga gatttatctc cataatctgc tcgatataaa ccatttattc
    70741 cagcagttct tccaatttca ctcaaatttc ttattaattc ctcttgatat tcagtgaatc
    70801 ttattttatt agtataagca gtaaaatata gataattcac caatctattt attaaaggac
    70861 cgggatctaa ttcatatttt tgtttttcta attttaaata taccttttgt aaaacctcaa
    70921 gaatatcaga atatttagga tctttactta tagatatatc attatataat tcatgaacaa
    70981 tttgcttagc attttttttc attttagcac ttccctggaa ttgctccacc taaaaaacca
    71041 cctatagaca ttcctgcaat acaagtagtt gccttggccc aatcgaccgt acatttattt
    71101 ttagtgcaat acactccatt tccataatat tttccactat gagtggtacc cccatagata
    71161 agttgtgtct ctttaataga caaaattttt aaatgtttca taatctaatc acccctaaat
    71221 taatgttttt agactattat tctaacattc attaaatttc aaaaaacaat tccttcttga
    71281 aacgtagcaa aataattcct gaataagaat ttaatcactt ttaagtatat aaactatgta
    71341 tattctttaa tattttttga gaatgcactt cgtacataat aaactttaat cacattagtc
    71401 tttcatacct acgatcgatc tctttgactc gcacccataa attcataata gtttgtcggc
    71461 gtctttggac gtttcgaaga tgagctacgc attctctttt tttatagaca aaaaagatag
    71521 agacgaacat ggagcttcca aatttggata tttgatccaa ttttggaagc tccatttatt
    71581 tcgtgtctgt ctttttattt tttccagctt tcgactaatt cttggttctc tttgatccag
    71641 tcttttgctg cttgctgtgg atcttttcca ttgttgattt ccaacataac tttttccata
    71701 tctttttctg accaatggaa attgtctaat actttgtaag cttctggctg gtcttctttc
    71761 aatccttttc gaaccatcgt atggatctgc tcttcgcttc ccattccgtt ttcaggatct
    71821 tctaagtatt tcagatcata tttggcaaac atccaatgag gtgtccatcc tgtaactaca
    71881 attggttcgt gttttttgat cgcttgacct agtgcaacgg tcattgctcc tgaagaagat
    71941 gtctctactt tccagtcttt caagttgtca tatttttgga tcgtgttttc agcagccgta
    72001 actacaccag ctcctggctc gattcctatg attttcttac ctgcctgatc ggttaactca
    72061 tcgatcgaat ttacatccat gtaggctggc actgctaaac caacttttgc tcctgtcaaa
    72121 ttggcaccta ggtcttcgac ttgatcttta tattgtgcat attgtgaacc atgagtttta
    72181 ggtagccaag ctgaaaccat ggcatctgac tcgccatttg aaacagattt ccacatgatt
    72241 gaattatcta atggcgtcat cgttacatca tagcccattt gtttcaatac ttcaccgact
    72301 acatttgttg aagcaacttc tgtatcccat tcaacataag ataagttgat acgttttgtt
    72361 tctttggcag atgaaaaact ccctatacca atcgcaccta agatcactac tactacagca
    72421 ccaatgatca gtccttgacg ttttttactt ttctgtgttg ttgctcctgc agctttttta
    72481 ttgtttggct ggttcaaatg ctgtgtaaaa cggtcaatga tgattgctaa gataactaat
    72541 gcaaccccgt tgacaaatcc attcccgact tgtgctcttt gcaatgctga taatacgccg
    72601 cgtcctaagc cgggtgcacc gatcatagag gcaataacga ccattgaaag tgacagcatt
    72661 gttgtttgat tgatccctgc catgatcgta cttttagcta aaggcaattc tagtttgaat
    72721 agtttttgac gacttgtgct cccgaatgaa tcagaagctt ctactaattc tttaggaact
    72781 tgtcgaatcc ctaaattcgt aaaacgaacg gttggtggca gagcaaagat gactgaggca
    72841 aatacccctg gaaccatccc gataccgaaa aatgcaactg ctggaatcaa ataaacgaat
    72901 cctggcattg tctgcataaa gtcaaggatc ggtttgataa tactttgggc tttactgctt
    72961 tttgccatca agatccctaa tggtacccca atgatgatcg agatcacact agataaaaga
    73021 acaagtgtga cagtattcat caaatcattc catagacctt ggttataaat aaaccataga
    73081 ccgattaatg tgaacaacgt aagtcctgga cgtttcttag aaataaagaa agctgctacc
    73141 gtcaataaca agataaacaa aggagctgga atcactaaca gtaaatttgt aatccccgac
    73201 atcactgcct gtccaatcgt ttgtaaaaat gaaaataggc cagaaaaagt tgtcgtaaac
    73261 cattctgtga tattttctac ccagtttgcc actggtaatt gatagttcaa tagattattc
    73321 atgttcactc acctcgcttg tttctgctaa tgcttcaatc acactacctc ggatgacgac
    73381 accttttaat tttccatcct ctacaactgc aagtggagtc ggtgagtcat aaataatatt
    73441 gaaaatatca cttaccacca tgtctttccc aatcaccgtc acattttcat ctaggaagtc
    73501 gatcaatgga cgtttttgct tcctagcttc taacgcttga tctgcagtga tgatcccttt
    73561 caggtgtctc tttctgtcaa cagccatcag catgctgact tcttcattac gcatccttgt
    73621 caatgcaacg tttggtccat cagattcgat attcgtcgtc aatgcaggta ccatgatgtt
    73681 ttgagccgta agcactttgg aacgatcgac ttcttccaca aattcacgta cataatcatt
    73741 tgctggattg gtcaatattt cttcacctgt tccgatctgc atgatttcgc cgtctttcat
    73801 caaggcgatt ctgtccccaa tccgtaaagc ttcattcaaa tcatgggtaa tgaaaataat
    73861 cgttttttga acattggctt gcaggtccag taattcgtct tgcatttctc gccggatcag
    73921 cggatcaaga gccgagaacg cttcgtccat cagcaagatc tcaggatcat ttgctaaagc
    73981 tctggctagg ccaacccgtt gttgcatccc accagataac tgactaggat attggtcttt
    74041 aaatgaaagc aaactagaat tttctaatgc tttttctgct ttttcttgtc gttcttcttt
    74101 aggtacacca cggacttcta acccgtattc tgtattttcc aagatcgttc gatgtggaaa
    74161 cagaccgaag ttttggaaaa ccatattgat tttatgacga cggacttctc gcaattcttc
    74221 tttgcttaac ttcgatacat cttctccatc aatatagata ctgcccgaag ttggctcaat
    74281 cagacgattc aatagacgga tcaatgtgga tttcccactc ccggaaagcc ccatgatcac
    74341 gaagatttct ccttctttta cgtcaaaatt cacgtcatac acaccaaccg ttgcaccggt
    74401 tttctttaaa atctccgttt tcggctggtg atcattcatc atatctaaag cggcttgtgt
    74461 ctttttacca aatatctttg ttaaatgttt tacttctact tttaccaaac aaattctcct
    74521 tttttatgta aattcatttt tctttctgaa aaaagtgacc acactatgtt aacatcatgt
    74581 agtcactttg tcaaaaatga aagaaatttg cttgtccaaa ctgaaaaaaa cttggctaaa
    74641 tctttgtaaa taaaaggttt agccaagtta atattttttt aatatttcac acaatcattc
    74701 tgcaagctga tgctccgggt aaaaaaagtt tgtcatacgc tgtagtgtat attcatttcc
    74761 aataaaatga acgatgtccc ctgccgtaaa tttagcatag gggccaggtg aaacaagcag
    74821 ttcttcatta tgagaaattg cgataactgt ggcgccagtc gcctgccaga tattcaactc
    74881 gctaattgaa cggtccagat gcattgcttt ttctgataaa gataattcaa acggaagtaa
    74941 aggattcatc ttatgtattc gcttcgtttg attgaccagc tgatccaata attgagaaaa
    75001 atgattcagc tcatcttgtt gcttctccac acttgccatg atttctgctt ttgtatcttg
    75061 gatggattgt acatcttgat attgcaatag gaaatctttt gctttttcct tcgaagcaac
    75121 aaatgcccca cttccatgcc gtacttccat gattccaaga tctaccagca cattgatagc
    75181 cttgcgggta gtctcaggag aagcattgta cgtactggca agtgttgagc gggcatggat
    75241 cttctcaccc actttatatc ggttttcaac gatacgttcg gctaaatcaa cagcaatctg
    75301 ctggtagcgc gggcggacga tttttttctt tccagacatt ttctttcctc tttctttttt
    75361 tactttccct catcttacta tgctctagca aaataagcaa aaaaggggag aatagcctct
    75421 tgcaacgact gatcatcgct tgatctgttc cttttttact gggcaagctg tttgacagtc
    75481 atcacaattc ttaccggatt ttaaacgagt atagacaatt gcgcctgcac ttccaaagat
    75541 taacacactt aataagaatg tcgccatcct attcctctcc ttctaatgac aatatagtat
    75601 aaaactggtt cttggatttt ggctgacgga acaaaacata aacgagtcct atcatcagta
    75661 aaatagcaag atacgtccct aacgctacct gtccaccctc caataagtgt cccaactgat
    75721 aaatcacaaa actaactaaa taagctaaac cgcattgata gcctatggcg atccaagtcc
    75781 atttcttggc attcatttcc cgatggatag ccccaattgc cgcaaaacaa ggcgcacaaa
    75841 gtaaattgaa ggctaacaat gaataagctg ctgcgggagt atatgtgtgt tgtagcactt
    75901 gccagatttc tctgccattt tcggatactt ccgcatgacc aaacaaaata ccaaatgtgc
    75961 caataatatt ttctttagcg accaatcctg taatcgctgc gactgttcct tgccagtttc
    76021 cccaaccaag cggctgaaaa acaactgcca ggattcgccc gaaaaaggct aagatacttt
    76081 ggtcttcaga aacaggttga gcataaaaat tataagaaga gctgaaccag atcacgatac
    76141 tagaaacaaa gataatcgtt cctgcttttt taacaaaaga cttgctgcgg tcataggttt
    76201 gtcttaggac cgctgaccat tgaggaaaat gatatgcggg caattccatg ataaaaggag
    76261 ctgtatctcc agcaaacaaa cgtgtttttt tcaagctgat tccagagaaa ataattgcag
    76321 tcataccaag aaaataggca gaaggagcta cccaagattg atgaggaaaa aaggcccctg
    76381 ctactaaggc aataatcggc aactttgcag aacaaggcat gaaggttgtg accatgatcg
    76441 tcaaacgacg atcttgctcg ttttcaatcg tgcgactggc catgacgcct ggcactccac
    76501 atcctgtagc aatcagcata ggaatgaagg attttcctga aagaccgaat ttcctgaaaa
    76561 gtcgatccat gacaaaagcg atcctcgcca tatatccgca gtcttccaga aagctcaagc
    76621 ataaaaacaa tataatcaat tgcggtagaa atcctaacac tgctcccacg cctgcgatga
    76681 tgccgttcaa gatcagctcc tgcatccatc ccgctacttg ccattcagct aacaatctgc
    76741 caacatgttc tggtaaccat gtaccaaaca atgtgtcatt gatccaatct gtccccattg
    76801 ttcctactgt ttgaatagcc agataataga tcagccacat cacaaatgcg aagatcggca
    76861 aggctaacca acgattcgtt gcaatctgat cgattttgtc actcatcgat aattggaaag
    76921 aatcatttga cacaacacag agtgtacata gttgggtaat aaattcataa cgttcattga
    76981 ccagaatcgt ctcactatcg tcgtccaata gtttctctgt taactggatc agttgctcga
    77041 tctctttttg ctgagaaact gctatctcgt aatcctctct taccttctga tctcgttcaa
    77101 aatatttcat tgcataccag cgtttcttgc cgctttgttc tcctagtaca tcttcaattt
    77161 catgtaaagc tgcttctaaa cgtggatcat atgtacaggg aacaggaata gaaggccgct
    77221 tttttgcaga ctcctgaatc ttttcgatta gtttttcgat tccttgcttt ttcaatacgc
    77281 tgattggtaa aactggtaca ccaagaccat aggaaagctt ttctagattg attttttttc
    77341 cttctttttt gatgacatcc atcatattca gaccaatgat cataggaatg tctaaatcca
    77401 ataactgcgt agttaaataa agatttcgtt ctaaattggt agcatcaata atgttgatga
    77461 tcagttcagg ctgttcctga accaaataat ctcttgcaat cacttcttct ggtgtataag
    77521 gagacaaaga atagatgccg ggtaggtcct gaatatgaat gttcggattt tttttcaacg
    77581 atccttcttt tttttctact gttacgcccg gccaattccc tacatattga ttcgaaccag
    77641 tcaagagatt gaacaagcta gttttcccgc tgtttggatt tccgactaac gcgatattca
    77701 ttctttttcc tccctttgta tcaagattag ttcggcctct gactttcgta acgtcagttc
    77761 ataccctcgc actgtcagtt cgattggatc tcccagaggg gctagttttc ggataactat
    77821 ttttacattt cgcgtcaatc ccatatccat taaccgtcgc ttcactgcgc cttgtccgtg
    77881 gattgctacg acgatcccag tctctcctgc ttttaattga tcaagagaag tccagctttc
    77941 agaggaagca gtctttttat tgacaaagat ttgacctagt atttcccgac ttactgccac
    78001 tcgatgactt tttaccagta aaatggcatt gttgcctgat aaattgacga cgacgatttt
    78061 acttccggca acgatcccga tattttgcaa atggcgtttt gttttttctt ctgtttcgat
    78121 tcgttcgact tgataaacga aattctgctt tgcctgcgct aaggtctgca tattgattcc
    78181 tctcttgtga aataaatcat gtattaaaat cattcattat atgttctaat tttcttacgt
    78241 gttacgcaaa taaatgagaa tcattctcac atagaatact ctcggtaatt gagaatgtca
    78301 attatacttg tgatattatg agcgaatctt tagtattgat agataaaaat gagaaaaaaa
    78361 tatttcttca tagttttcca caattttttc tctattaaat ttgctatttt cccacacgat
    78421 acttgttttc agctcttttt tcaaaaacac aaaacttagt attccacagt ttccacaaca
    78481 caatatgtag tgtttgttgt ttgacttttt tactaagagt tttatactat ctattataga
    78541 taataagaat gtgttagagg aggcactcac catgaacgta aaaatctttt ctaaaaataa
    78601 ttgtatgcaa tgtaagatgg tcaaacggtt tttaacagaa aatcaaattg cttttgaaga
    78661 agtcaatatc gatgaacagc ctgaagcagt agactggttg aaagcacaag gattccaaag
    78721 tgttcctgtc attacttctg atgcagaaac agttatcgga ttccgtcctg atcagttgcg
    78781 taaacttgcc agctaacatg actaaaagaa tcaaaacgtg atacatggat ttgaagggct
    78841 tgagacagca ccagtttttg tcgcaaactt ccaaatcctt ttttaaagct taaaaacaat
    78901 gcaatgattt gcaatcaagc atcatcaaat acgaaatgaa ggttgggcgt acgtatgagt
    78961 cttaaaaatt tacaagatgt cagttatttc aagctgaata atgaaatcaa tcggccagtc
    79021 aatggtcaaa tccctttgaa taaggataaa gaagctttag ttgccttttt tgaggaaaat
    79081 gtcaaaccaa atacgatgac ttttctatct attatggaaa aaatcaatta cttgatcgat
    79141 caagaatata tagaagcaga attcattcaa ttgtattcac catcatttat tgaaaagcta
    79201 tatcaatttt tggacgagca acatttttct ttcaaatctt ttatggctgc ttacaaattt
    79261 tattctcaat atgcgttgaa aaccaacgac ggttccgctt atctggaaac ttatgaagat
    79321 cgagtagcct tcaatgcgct ttactttgcg aacggggatg aagaattagc acttgctctt
    79381 gcagacgaaa tgatccatca acgatatcag ccagctacac cttctttctt gaatgctgga
    79441 cgtaaacgtc ggggcgaatt ggtgtcttgt ttcttgactc aagtcactga cgatatgaac
    79501 tctatcgggc gctcaatcaa ctctgctttg caattgtccc gtattggtgg cggcgtaggg
    79561 attactttat caaatcttcg tgaagccggc gctcctatca aaggatatga gggtgctgca
    79621 agtggtgtcg ttccagtcat gaaattattc gaagatagtt tcagctattc taatcaatta
    79681 ggtcagcgtc aaggagctgg cgtggtttat ttgaacgttt tccatccaga cattattgct
    79741 ttcctttcag caaaaaaaga aaatgcagat gaaaagattc gcgtaaaaac tctttctctt
    79801 ggcgtgatcg tacctgataa attttatgaa ttgacacgta aaaacgaaga tatgtattta
    79861 tttagtccat atagtgtcga aaaagaatat ggtgtcccat tctcttatgt aaatattaca
    79921 gctgagtatg atcatctagt tgcaaatcca aacattcgca aacaaaaaat caaagcgcgt
    79981 gatcttgaaa atgaaatctc aaaattacaa caagaatctg gctatcctta cgtaatcaat
    80041 attgatacag cgaaccgcga gaatccaatc gatggcaaga tcatcatgag taatttatgt
    80101 tcagagattt tacaagttca aacgccttct gtgattaacg gcaaacagga atatgaagta
    80161 ttaggaacgg atatctcatg taacttaggc tcgacaaata tcgtgaattt gatgcaaagc
    80221 cctaactttg gtcaatctgt gcgtacgatg actcgtgcat tgacatttat tacagatgca
    80281 tctgatatcg atgtcgtacc accgatccaa aacggaaata agctgaatca tacgattgga
    80341 ttaggtgcca tgggcttaca cacttatctt gcaaaagaac aaatggaata tggctcagag
    80401 gattcattag actttacaaa tatttacttc atgctgttga attattggac acttgttgaa
    80461 agcaacaata tcgctcgtga aagaaaacaa gttttccata attttgaaaa atcagcttat
    80521 gctgacggca cttatttcga aaaatacgta actggagaat tccagccaaa atcagaaaaa
    80581 gtcaaagcat tgtttgaagg catttttatc ccaactgctg aagattggaa tgctttgaaa
    80641 caagcagtaa tgaaagatgg actgtatcat caaaatcgct tggcagtagc accaaatggc
    80701 tcaatttcat atatcaacga tacgagtgca agtattcatc ctatcactcg catgatcgaa
    80761 gaacgccaag agaagaaaat cggtaaaatt tattacccag cgccttatct atccaatgag
    80821 acgattccgt attacacttc tgcttatgat atggacatgc gtaaagtaat cgatgtttat
    80881 gcaatggcac aacaacacgt cgatcaaggc atgagtttga ctttattcat gcgttctgaa
    80941 atcccagaag gcatttatga atggaagaca acaacgaagc aaacgacacg tgatttgaat
    81001 attttaagac attacgcttt ccacaaagga atcaaatcca tttattacgt acgtaccttt
    81061 actgatgatg cagaagaaat cggaagcaat caatgtgaaa gctgcgtgat ctaatatcat
    81121 agatagattc gcttattcat attttaatta aaggagcatt ctcatgtcag aaacatatta
    81181 tgaagcaata aactggaatg aaattgaaga tatcattgat aaatccactt gggagaagct
    81241 gacagagcaa ttttggctag atacacgtat cccactttca aatgacctag atgattggcg
    81301 tacattgtct caattggaaa aagatacagt aggacatgta tttggcggtt tgacactgct
    81361 agatactgtc caatctgaaa gtggcatgga tcagttgcgt aaagatgtcc gcactcccca
    81421 tgaagaagcc gttttgaaca atattcaatt catggaatcc gttcatgcca aaagttattc
    81481 ttctattttt agtacactga atacgaaaaa agaaatcgaa gaaatttttg actggacaaa
    81541 tacgaatcct tatctgcaaa aaaaagctga gcgtatcaat gaaatctaca aacacggtac
    81601 accgctagaa aagaaaattg ccagcgtctt tttagaaaca ttcttgttct attcaggttt
    81661 ttatactcct ctttattatt taggaaacaa caaattggct aacgtagcag agatcatcaa
    81721 actaatcatc cgagatgaat ctgtacatgg aacctacatc ggttacaaat tccaattagg
    81781 attcaacgag ttacctgaag cagaacaaga aacgttaaaa gactggatgt acaatcttct
    81841 ttatgagctt tacgaaaacg aagaacgtta tacagaagaa ttatacgatc caatcggctg
    81901 gacagaagaa gtcaagacat tcctacgcta taatgccaac aaagcattga tgaacctagg
    81961 gatggatcca ctctttccag atactgccaa tgatgtcaac ccaatcgtaa tgaacgggat
    82021 ttcaacaggc acaagcaacc atgacttctt ctcacaagtc ggaaacggct atttgttagg
    82081 tcatgtagaa gcgatgaaag acgacgatta tttgattgga ttggaataag gatttatttt
    82141 aattcaaaaa tttttcgaaa aataaaaaga gtttagcgta cagatatttt aaatgtacac
    82201 tgaactcttt tttatgctta ttcacttgtt tcttccagca cttttggact gtctaacttt
    82261 tccgaaacat gttccattct tctcaataaa tagattttcc ggatatttaa tattatcgtc
    82321 ttaatcactg catagacagg tatgcaaatc agcatgccta atattcctgc gacacttcct
    82381 gctccaatca ataccaagat gatcgtcaaa ggatggatat tcattgattt cccaaataac
    82441 aacggcttga tcaaatttcc atctaattgt tggatcacta aaatcgacaa cgccatatac
    82501 aaagcttgaa atggagagat aaacaaaccg acaatgattg ctggtaccgc tccaataaaa
    82561 gggccgacat acgggataat attcgtgatt ccgcaaatga ccgcaagcaa caagctataa
    82621 ggctgatcga atattctcat tgccaaaaag ctcattacac caataatcaa agcatctaag
    82681 atcgtactgc tgatataggc agataatgtt tcgtttaatt cttttaccgt ttggcgtaac
    82741 tctttacgaa tcgctttcgg aaagaagtga gacaacgcat caataaattt gtgcccatcc
    82801 ttgaacataa atagcaaaat aaatggaacg gtaaataaca aaataaaaaa ttgcatcata
    82861 aatgaaatga tttttgagac acttgcagat aaactgacta atatgatatt gaacaaatta
    82921 ctaagagata aatttgctga tgctaattgt tcttccaaat tgaaattttt aaactcttcc
    82981 cgctgcgcca attcatttaa ccatttgctt gtttcatctg catacattgg caagctctgg
    83041 gtcaattgaa ttgtctgttc cattaactga ggcactacat tcatgacagt taaaacaact
    83101 aaaatgatta cgaccaaaaa cgtcaataaa aaaccgaaca ctctcgggat ccgatgcttt
    83161 tcgagaaaaa caacgattgg atcgaacata taatagataa aaccagcaac aagcaatggt
    83221 aaaaaaactg ccgaaagcat tttcaatatt ggactaaaaa tattcggcat ttgtaaaata
    83281 aagtacacgc cgatgatcgt gagtactagc tccactgtcc agaaaaataa ttttgattgt
    83341 ttaaaacgtg attgcataca tctcctccaa ggtcctttga tacttctatt ctatcattta
    83401 acaaagagtt acgcgctgag attttcattt gcttaaaaaa aacaaaaaaa ataaacatat
    83461 tttaatgagt agacgagtac ttaaacaaaa acacggtttg gagtagtgac aaaaattata
    83521 ctgcagtccc tttttccaaa taaacggtgt tcaaaagctt gcatcttcgt aataagccca
    83581 gccaaacgaa aaatataagg aactattttt atttggctgg gcttattact tgatgtagga
    83641 catctatttt acaacctcag atcatttatt gcgcaatact gactaaatgc aactttgtga
    83701 tatttttgtg tacggacaac tcctcgatca catcggcata agtgagccct tttggaagat
    83761 caatcgtata gatatttttg tacactcggt agtcatcaac gaattttacg tcaaaattca
    83821 catcttcgat tacgatattt ttctcttcaa aataatcggt aagaaaatct ttggtttctt
    83881 ttctatggat aaattggatt tctaactttt tagtcgtagg tacatggatc acgcgtttca
    83941 ctactgtgag tgcaatagca atcccgataa aactgatgat cgcaatggaa tagtaaccca
    84001 tgccgatggc gatccctaat ccagcaattg cccataaaga agcggcagtc gtaagtcccg
    84061 tcaccgattg tttcgtgacg atgatcgttc ccgcgcctaa gaaaccgaca ccactcacca
    84121 cttgagcaat cagccttgct tcatctgaac gaatcgttcc agcaagctgt ggatactcta
    84181 aagcatctct taatgcacca ctagcgatct caacttggat caatgcaatg atacatgctc
    84241 ccatacaaac taaaatatgc gtacgcatac ctgctggacg atttttatat tgtcgttcaa
    84301 aaccgattgc tccgccaaat agcatagcga tccctaaacg taaaataatc tctggaattg
    84361 tcaataccat atcattcatc taaacaccct ccagtccaat atatcatgtc tgaaaggagc
    84421 agacaaaaaa agtgcaattt ttacctctta cgaaaaaagg actgtgacaa aatttttgtc
    84481 atagtccttt ttatgaataa acggtgttca atcagctgac cctcggtatt actcaacaaa
    84541 cggcaaaata tggggagcta tttttccttt gtcttctcta atactcaggt caaaacgctg
    84601 atttcacaac ctctttagcc tactattgaa aattacaact tacttgctgc ttcttcatcg
    84661 atgatcacaa caacattgtc gtgattttgc aatacacttg ctggcaaatg attcgttaca
    84721 ggtccttcaa tcatcccttt gattgcatca gctttgcttt cgccaaatgc catcaagacg
    84781 atttctttac ttttcataat tgaaccgatt cccattgaaa cagcttttgt tggtacatct
    84841 tctgctttat cgaagaatcg tttgtttgca ttgattgttg attctgttaa gtcaactact
    84901 gaagtcgttc cgtcaaatga agcaccaggt tcattgaaac cgatatgtcc attttgcccg
    84961 attcctaaga tttggatatc gattggatgt gcatcgatga tttgatcata ctttttgcat
    85021 gctgcttcca gatcttctgc ttttccatct ggtacaaacg tttctttgaa tggtttttta
    85081 tcaaataatt ggacatccat gaaatgacgg tagctttgtt catctgaacc gcctagtcca
    85141 acgtactcat ctaagtttac agaagtcatt tcactgaaat ccaaatcgct tgaagtcatt
    85201 tctttatata aagtaactgg tgtgcttcct gttgccaatc ctaatacttt tgcacctttg
    85261 ttcatacctt ctttgatgat ttcaaatgct ttttttccgc cttcttcagc gttttttaca
    85321 cgaatgattt ccatagtgat tgctccttta tattttggta tagcccaatt atagcattct
    85381 ttttttcttt ttacaataat tagtatagac caaattgcat ttttttcatt ttcttgacaa
    85441 taaataggaa tccgtgttag gtttcataag atggttcaat caaacaatcc atgttgcatg
    85501 aaaaccaagc aagtgattca ctgtggacgc tttatgtctg cagttttttt atgaaaaagg
    85561 agttattatg agtatactga cattaaacaa cattacccag caatttggcg acaaaatcct
    85621 ctatgaaggt gtcgatctgc aattaaatgc tggcgaacat cttgggctga ttggacaaaa
    85681 cggagccggt aaaagtacat tgattaaaat catcactggt gagatcttac cagatgacgg
    85741 acagatccat tggcaaaaaa atattcacaa aggttacctc gatcaatatg tggaagtcga
    85801 tgaaacatta acaatcgaag aatttctaaa aactgcgtac gcaaaagaat acgaaaagga
    85861 agaaaaaatt gcttttcttt accaaacata tagcgagacc ttcgatgatt ccttgctgga
    85921 aaaagctggg aaactccaaa cggaattaga ccaaggagtg ttttatcaaa tcgacacctt
    85981 agttgctgag atgagcagcg ggttggggat cgatgtctta ggtttagatt cactgttgaa
    86041 aaatctaagt ggtggacaac gttcaaaggt gattttagca aaactacttt tagaaaaccc
    86101 agatgttctg atcttagatg aaccaaccaa tcacttagat gatcagcata tccaatggct
    86161 gacgcagttt cttcaggatt ttgacggtgc gtatatcgtg atttcccatg accaagaatt
    86221 tcttgatcag atcaccaccc atatcgcaga catcgagttt ggaaagatta ctaagtatac
    86281 tggccatcta aaacaagcat tgaaacaaaa ggaacaaaat cgcgaaagct atttgcgcca
    86341 atatcatgct caacaaaaac aaatcgaaaa gaccgaagct tatattcgaa aatacaaagc
    86401 cggttcccga tcaacgatgg caaaaagccg acaaaaacaa ttagataaaa tcgaacggct
    86461 gacgcctcca gcttcagcaa gtaaagctgt ctttgatttt ccattctcgc ctattgtcac
    86521 gacattagca gtggaaacaa ctgatttagt catcggatat gatcgaccgc tacttgcacc
    86581 catcaatttg accatccgct ttggtgaaaa tattgccatt cgaggcttca acgggattgg
    86641 aaaatctact ttattaaaaa cactgatcgg tgagattgaa aaaataagtg gcgatttcca
    86701 cttcccagat aacacaaaaa tcaattactt ttcacaagat ctgtactggg aaaatccatt
    86761 agaaacacca ctacaatatt taagcagtca atttccaaaa gcgactatca aagaattacg
    86821 tcgccaacta gctaaagcag ggttagttaa tcaattagca agtgaacctc tcactacatt
    86881 aagtggtggg gaacaaacta aggtgaaact tgcacagttg acaatgaacc aaggtaattt
    86941 actgattctc gatgaaccga cgaaccatat cgatcaagaa acgaaagaaa gcttacaaga
    87001 cgggatacag aaatttccag gaacagtaat catcgtctct catgaacaag aattttatca
    87061 agatcttgtg caacgagtca ttgagattga accaaaataa acgtttgatt gaatagttga
    87121 aaaaaaggag ctgtgacaaa agttttgtca caactccttc ttctgaataa atggtggcca
    87181 attagctgac cttcggtatt agctcaaaaa acggcaaaat atgaggagct atttttattt
    87241 ggctattctt attacttgat gcagaacagc ttttcacaac ctcttttcgt ctatttttta
    87301 ttttcgagat ttctctttcc tttaaaaaca actgtttgaa agaagaacgc acatccttga
    87361 aaaacaagcc cgctaaccgt tacacctaac cagccatact gctgccacat tgtcgtccct
    87421 agcaatgaac cagccgcacc tccaataaag tacataaaca taaatacagt attatttcgg
    87481 ttgcttgctg cttcacctag cccctgtact cgtgtttgat tggcgacttg accaaattga
    87541 ttcccgacgt ctaataaaat aatagctaaa agcaaaatgg ccaaatggct tccgccaacc
    87601 aataaagcaa taaagcttat tgtttgcata acaagtccca tatacacgat ttttctttca
    87661 gaataagaat ctgccagtcg tcccacgata ggtgcagcaa ctgctccaga caaaccaaaa
    87721 atcgctaata tccctgcttc gaatgttccc caattgtagg cgggactgct gatataaaaa
    87781 atcaacgtag accaaaagat cgaaaatgtt ccaaacatga aaaatccact gactgccgct
    87841 tctcttaata gacgttgaga agcaactaaa tgcggcaaac ttttaagtga atcaaggtat
    87901 gaaacagctg tactactttg ctggacagaa cgcggcattt tccagtaaag cagaagtgta
    87961 agaattccga ctgcacataa agcaaataaa tagatcatcc gccaagaaaa aagactggca
    88021 acaataccag ataccgtccg agaaagcaaa atccccacga gtaaaccgct aagcaatgta
    88081 cccatgacct tccctcttgc ttttggtccc gctagtaccg caccgtaagg aatgatgatt
    88141 tgcggcacga tcgaaagtaa tcctattaaa aaagaagcgc atgcaaataa cgtaaacgaa
    88201 ggcgcaaaaa aagcggccaa cagagagacg gcagataacg ctgccattcg aatgatcaat
    88261 tttggacgat ccaccacgtc ccctaaagga actaaaaaca gtaaccctaa cgcatagcct
    88321 aattgggtca acatcgtcaa tatcccgact gcacttgtgc taacagataa actagctgct
    88381 acttttgttc caatcggctg gatgtaatac atattggcaa caacaacgcc acaagtgatt
    88441 gataatagta aaataagcga agttgttaaa ggtttttttt cattactctt cattgatttc
    88501 ccccatttcc tatcttagtt tacaacttat ggaaaagatt ggaaatagaa aaatacaact
    88561 attcgccaca cttattattt gtgcttttgt tttccttgtt ttttcttgcg atctttataa
    88621 atgaagacaa ctaaccctac tagcacagta acacttgcaa ccaacgtgac tgcagttttg
    88681 ttatatccgt gaaacagagc ttctccacca cacgcataca acacagacga agggatgact
    88741 ccaatcacga tcgacaatat gatttgctgt agaggcaatt tcatcgcatc tgcagcaaaa
    88801 ttgaccatag aagatggaat aaccggtatc atatagccta acattacacc tatttttgga
    88861 tgtttcattt gtcggattgc ttgcacccaa tgattcgttt cggttttctt atctaaaaat
    88921 tttaagcgat gcataaggaa aattgcagtg atgttaccaa gagcattacc caaaatgttg
    88981 atgatcgcac ctgtcagtgg tccaaagctc aaaccagcaa tgactccaac tactgaagta
    89041 ggaatacctg gaacagcaca catcaccgct gtcaatacga tcaagagtat cgatgcaaaa
    89101 gtcccatgcg aacgaatatg tgcgagtagc tctgccttac tcgctctcgg atttaaaaat
    89161 aattggatgt ctgtctgata ttctaaatac aaccgatagc ccactaccag tatcagaatg
    89221 attcccaacg agatcaatat caatcggatt attttctttt tcatatttcc tcctgaaaaa
    89281 aatctatatt cattaaataa tagtttaaca taaaaacaaa aaagcaccga aatccaacat
    89341 aggatctcag tgcttttaaa tagtaaaaat tatttaacag ttacagatgc gccaacttct
    89401 tcaagtttag ctttcaattc ttcagcttct tctttagata cgccttcttt aactggtgca
    89461 ggagcgccat caactacagc tttagcttct ttcaagccta aaccagttgc ttcacgaact
    89521 gctttgataa ctttaacttt ttggtctcca gctgcagtta attctacagt gaattctgtt
    89581 tgttcttcag cagcagcagc gccaccagca gcagctacag ctacaggagc agcagcagat
    89641 acgccaaatt cttcttcaat agctttaact aggtcgttaa gttctaggat agttgcttct
    89701 tttaactcag caacgatgtt ttcaatgttc aatgccatta taatttcctc cgtttaattg
    89761 ttctttttta tttaatgctt tatgcggcaa ttaagctgca tctccatctt ctttgtctgc
    89821 cactgctttg acagcgtaag ccacgttgcg gactggcgct tgtagtacag atagcaacat
    89881 agatagaagt ccttcgcgat ttggcaattt tgccaatgct gtgatttctt ccaatgaaga
    89941 gactttacct tcgatgatac cgcctttgat ttctaatgct tttgcttctt tagcaaattc
    90001 gtccatgatt ttcgctggtg cgactacatc ttcgttactg aatgcaacag ctgtaggtcc
    90061 agtgaatact tcgtccatgc cttcaaggcc agctttttta gctgcacgtg aaagaataga
    90121 atttttgata actttcattt ctacgttagc atcacgaagt tgtttacgta aacgtgttac
    90181 ttcatcaact gttaatccgc ggtagtcaac gactactact gatgcagctg ctgtaaattt
    90241 ttcgcttact tcatcaacga ttgctgcttt ttttgcgata attgcttcac tcatttttga
    90301 gtttcacctc ctgaattttg atggaagagt tttttgcact gaaaaggcaa gtcactttta
    90361 tagttacttt gctcaaccag tattattcat cacctattca cttcgttcat agtgattcta
    90421 ctcgctttgc tcgaaaggaa actcctttcg ctttgctcaa ccagtattgt tcatcatctc
    90481 ttcacttcgt tcatagtgat tcacaataaa aaactctatg ccaccgcaga catagaggga
    90541 ctattgaata tattcaataa acgtcctcgg taggaaatta aggcttgatg ccacctactg
    90601 tcttcggtac aagttaatta ttaacctcaa ctagcttagc atgctaaact agttgagtca
    90661 agaattattt ttcagttgga tcaatcaaca ttctaatatt taattagaaa gaagcttggt
    90721 caacatggat accaggtcca aatgttgttg tgatcgttac atttttcatg tattgacctt
    90781 tagctgctga tggtttagct tttagcaata catcatggat tgctgcaaag ttttcaacta
    90841 atttttcatc gtcaaatgaa acttttccga ttggtacatg gatatttcca gctttgtcca
    90901 cacggtaagt tactttacca gctttcactt cgtttactgc ttttgttacg tccattgtaa
    90961 ctgtaccagt tttagggttt ggcattaagc cttttggtcc taatactcgt cctagacgac
    91021 ctacagtagc catcatatca ggtgttgcaa caactacatc aaagtcaaac catccgtttt
    91081 ggattttttg aaccatgtcg tcgtcaccta cgaaatctgc accagctgct tcagcttctt
    91141 ttgctttgtc tcctttagca aaaactaaaa cagtttgtgt tttaccagtt ccgtttggta
    91201 atacaacagc accacggatt tgttggtctg cttttttagg gtctacgttc aaacggtatg
    91261 caacttcaac tgttgcatca aattttgcaa tgtttgtttc ttttgctaaa gctactgctt
    91321 cggcaacagg ataaacttta cttgaatcaa ctttttttaa tgcatcttgc atttttttgc
    91381 tctttttagc cattttggtt cctccttgat tgtggttata acggttgtac ctcccacgtg
    91441 ttctatatct ttcaatatag agccaactga gaagctgctg tcttagggtg tatagattat
    91501 tctacagtga tccccatgct tcgtgcagtt ccttcaacca tgcgcattgc tgcttcaacg
    91561 ttagctgcgt ttaggtcttc catttttaat tcagcgattt ctcttacttg atcgctagaa
    91621 actttcgcaa ctttattttt gtttggttcg cctgaacctt tttcgatttt agctgctttt
    91681 ttcaatagaa cagcagctgg cggtgttttt gtaacgaatg tgaatgaacg gtcttcgtat
    91741 acagaaataa caaccggaat gatcaaacct gcttgatcag ctgtacgagc gttgaattct
    91801 tttgtgaatc ccatgatatt gatacccgct tgacctagtg caggacctac tggtggagct
    91861 ggagttgctt tacctgcagg aatttgcaat ttaacgattt tttctacttt ctttgccacg
    91921 agacatacct ccttaagtcc gtgatgtggt taattggaga tgcatatttc tcctcccacg
    91981 ttttatctga tctgaaaaaa tccagacaaa taatgtgcaa aacaatgcac actggtacag
    92041 tatagcaaat ttatttgttt tttcaagatt tttttctgct atttttacat tttgcttgaa
    92101 taaacgctaa atttattcta aaaaaacaac aatttttcgt tctcatttct tcttttatgt
    92161 tacacttgcg ctagcatggt tcaacagatg aaagcaaaca ataacacggt tttttagacc
    92221 cttgtacaaa gattcctaca taacaaaatg aggtggagaa aatgaaagat ttaaggtata
    92281 gaagtgtctt tgatattatt ggacctgtga tgattggtcc aagtagctct cacactgccg
    92341 gagctgctag aatcgggaaa atcatacgta gtatatttgg cgaacagcct gattctgtag
    92401 atatttatct atatgaatca tttgcaaaaa cctatcgggg gcacggaaca gatattgcat
    92461 tagttggcgg cctgttaggg atggaacccg atgatgaacg tttagctgat tctttgaaat
    92521 tggcatatga agccggtatg gaagtcttgt ttgttcctaa gagtgaaaaa gccgaacatc
    92581 caaactctgt aaagatgctt ctaaaaaaag gaacacgaaa gctttcagtc actggcattt
    92641 cgatcggcgg tggcaatatc cagatttctg aattgaatgg attcaaaatt tctttaagca
    92701 tgggtactcc taccttgatc gttgtccacc aagatgttcc aggtatgatt gctaaagtga
    92761 ctagtatact ttctgagacc aatacgaata tcggcactat gacagtgaca cgggaatcaa
    92821 aaggtgaaaa tgccattatg ataattgaag tagatgatcc tcaagtagaa gaaacggtaa
    92881 aaagactcaa acagctgcca aatatcgaca gcgtaaatta tttcgattaa ggagctaaaa
    92941 aaatgttttt atcgattgaa gaattagtag atcaagcaaa agcttatcca agtgtagcag
    93001 aattgatgat tgcagttgaa atggaaatga gtggccgttc ccgtagtcac atcatcgaga
    93061 tcatggaaaa aaacctctca gtaatggaac aatcaatcaa cgagggaaaa gaaggtgtta
    93121 cctccgtcac aggaattacc ggtggtgatg caaaaaaatt agatgattat ttaaatgagg
    93181 cagacttttt aagtggagaa acaatcttaa aagctgtacg caatgctgta gctgttaatg
    93241 aagtcaatgc aaaaatgggg ttgatttgtg ctacaccgac tgccggaagc gcgggtgttg
    93301 ttcctggtgt gctgatggct gtccgagatc ggcttgattt gacacatgaa cagcaattgg
    93361 aattcttatt taccgctggc gctttcgggt tagtcatcgc aaacaacgct tctatcagtg
    93421 gtgcagaagg gggatgtcaa gcagaagttg gttctgcaag tgcaatggca gcagcagctt
    93481 tggtttgtgc aaaaaatggg actcctcatc aagcagcaca agcagtagcc attacattga
    93541 aaaatatgat gggactgatt tgcgatcccg ttgcaggctt agttgaagtc ccgtgtgtca
    93601 aacgtaatgc tttaggctct tctcaagctt ttatctctgc tgatatggca ttagcgggta
    93661 tcgaaagtgt cattccgccg gatgaagtcg ttgctgcaat gtaccaagtc ggacgtcaaa
    93721 tgccgtcgat tttcaaagaa acagcagaag gtggcttagc tgttacgcca actgctaaac
    93781 gacttgcgga agagatttta aataagaggg cgtgataaag ctccttaatt tcgagtatta
    93841 agagattagt tatcttcata acaaaaaacg aagagaggac taattgccct tctcttcgtt
    93901 ttttattaat ccatcaattt cgtatatttt acttcatcga tcgtttttgt tcctgcaagt
    93961 tgcatcgtga tcgacaattc tttgttcagg tgttcaaaaa cagatgttac tccttctgcc
    94021 ccacctagat tcaacccata aatcactggt cggccaatcg caactaagtc agcaccactt
    94081 gccagagctt tgaagacatg ctctcctcga cggacaccag agtcgaaaat cactggtaca
    94141 cgtttgttga ctacttcggc aatttttggc aatacttcaa aggacgcagg acctccatct
    94201 agttgacgtc caccatgatt ggatacccag ataccatctg cccctgcaga gatagcgatt
    94261 actgcatctt ctggcgattg tattcctttt acgataactg gaagatgggt gatttctttg
    94321 attgttttga tgtcatctgg tgtcaagcct tgttttgcag ctgcataaat ttctgcgatt
    94381 ccttttcctt cgccattacc acttgcactt tgttcgctat acgcagctaa gttaggcatt
    94441 ggtaatggaa attggaattg attgatgacg tcttcttcac ggtaaccacc gagcgttgaa
    94501 tctgccgtta aaatgatagc tttagcccct gcttctactg ctttgttcaa aatgaactca
    94561 ttgaatctgt cgtctttact catatataat tggaaaaact gcggtgcgcc tggcgctgca
    94621 tcggctgcgt ctttgattgt cgtatttgca taagtgctga tggaaaagat tgatccagca
    94681 gcagctactc ctttagctgt atcagcttcc cctttttcat gtgccaatcc ttgggccgct
    94741 gatggcgctt ggataatcgg tgtatctaat tcaattccga aaacagatgt atgcaaatcg
    94801 gctgagtcga ttccgcgtaa tatccgtggc atgattttct ttgtattaaa agaagtcgta
    94861 ttttctttca tcgtccactc atcttcagaa ccaccgcgaa tatagccaaa agctcctgct
    94921 tccatgcgct cttttacacg accttctagt taggcaatgt ttacaatatc gattggatgt
    94981 tcttcattac ttgtatgata agtcatagta gatccttctt tcatcttctt gattacatat
    95041 aaatcatact aaacttacaa aaagtaagca aacatttact ctcagatact tttatcgcta
    95101 ttctttccaa ataaatcgac ttacaagctg atctacttct tggttttcat gaagcatact
    95161 atgagaggca ttttcacctg tcactacttt ttcctctatt tcatttccgc gttgcttcaa
    95221 caacgcatag accgctaatg cactgtttaa cggtactgtt ccatcactca agtctgtttc
    95281 atctagttga ccagcaatca agaaaaatcg agtggttata ggaatattac cgatcatttg
    95341 ctggtaatct tgatagcggt tagaaacgac agcaggcccc tttgctaact catctgtcag
    95401 agactgcgca ctatcatcga caaaatcatt aaaaggcgcg ccaattgctg ttaatgtctg
    95461 aacttgtggc aatgacgtat cctgtccata cgttcctaaa tagcgtagtg cactaactcc
    95521 tcccatggaa tgccccacta tgttgacttt atctatgccg tagttttctt tcagatacaa
    95581 aagacaagtt ttgatccatt ctgcttgatt ccactcgtta tttttattat cttcaaacaa
    95641 tacttggacc atcggattgt ctgcttttcc agacaaatct cctgttgctt gtatttgtcc
    95701 atctgttcct actgttaaaa ccaattcttt tactgcttgc tgattttttt ccaaacgccg
    95761 caacatccct ttaaaggaat tttctgtccc gctgtagccg tggaaaaaaa gtgttggaat
    95821 agtggttttt tctatcactt tactggattc tgccgttttt tctttatcag aaacttcagt
    95881 agtatttatc ttcgtcgtct ggcaaccact taacgcaaac aaactgataa ggactaaagc
    95941 tgctgcagtt gcacgtttgc ataaattttt gattggttct gtcatacacc tcttcctttc
    96001 catatagaaa aaagaaagac ttgaaaggcc aatcatatga tcgacatttc aagtctcttt
    96061 attaatcgat tttatctact tgatcgaaat caagttctgt actggtttca cgtccaaaca
    96121 tatcgatgtt gactttcaat ttttcttttt ctccgtcaac ttctgttact tgtccttcta
    96181 atccagcaaa tgcgccttcg atgattttca cgacttcgcc aacttctact tctagatcat
    96241 tttgtcgcag gctcataccg atagaacgca agatatgatt gacttcttct ggaagtaatg
    96301 gtgctggttt gcttccggct ccgtgtgaac caacgaatcc tgtcacacca ggtgtgttgc
    96361 ggacaacata ccatgaagcg tctgtcatga tcatttcaac aagtacgtat cctgggaatg
    96421 ttttatgaac gatttctttt tctttcccat ttttgacttc agtttctttt tcttcaggaa
    96481 caacgacacg gaaaataaag tcggccattt tcatactttg cgcacgagat tcgatatttg
    96541 cttttacttt gttttcatat cctgaatatg tatgcaagac ataccagttt ttttcaaaag
    96601 attccattga aggctcctca tttcattgta aaataaaaaa acctcagtac acccgaagtt
    96661 tttctttcgc ttcattatag cactaaaagt acgttgtggc tagcgagtta ttttaaaatc
    96721 cagccaaata agctttggat ggctgtatcc attacgtaaa acatcaatcc gaaaataata
    96781 gaagtttcga tgactactaa cgtatcttta cggagttgtt ttctgcttgg ccaagttact
    96841 tgtttgattt catcttttac gctttttaga aatttcatga gacaacctcc cttgctactg
    96901 tttatttcgt ttctttatgt aatgtatatt gattacaata tttacaaaac ttattgattt
    96961 ccaaacgttc gccgcttttt ccttcactga ctgattttgt gtagttgcga gacccacaaa
    97021 cggaacaagc gagtgctgct tttttctttg ccatttactt ctgccccctt gctgagaatc
    97081 agacttatac ttcataacag tatcacgtaa ctttttactt gtcaatttgt gaaataaact
    97141 atctattgtt ttggataaaa ttatgatatg attaatttga aattaagcta aaatgagaca
    97201 attggaggta tagcgatgct attaaaaaca cttgtatata agaaaaaaga tctgacaacc
    97261 gttacagaga ctagtacatt agaagaagca ttaaaaattt tagaaacttc cggataccgt
    97321 tgtgtgccga tcttagattc ttcaggtaat attttccgtg gaaacattta caaaatgcat
    97381 atctatcgtc ataaagcaaa tggcggtgat atgacgcttc ctgtcactca tcttttgaaa
    97441 aacgctacaa agttcattta cctggatact tctttcttca aagtattctt tacgatcaaa
    97501 gagcttcctt atattgctgt ccttgacagt gaaaatcatt tttatggtat tttgacacat
    97561 agtacgttgc ttaatatgct ctctcaatct tggagcgtag aacaaggaag ctatgtactg
    97621 acaattgctt ccacaggaaa gcaaggagat ttggctgcta ttgcaaaaat catttcaaaa
    97681 cacagcagca ttgccagctg tattactctt gatatcgaaa aagacgaata cattcgacgt
    97741 acattgatca cgctaccggc taacactgaa gcgaaagtat gtgaaacgat cgtcaaccac
    97801 ttagagaaaa agaattataa agtggtagaa attgaaaatt tgcaaaacca agaagcataa
    97861 tcaaaaagcg aaaaaagaaa acagctaatc tgctttcttt tttcgctttt tataattaga
    97921 cacgcttttc aaaatcaagc gcgcgatcta aataatacat caatggtgct gaaacagcca
    97981 tgacgataaa ctcacttaat gcaagcgtgc cataggttgt ccaaaatgct tggccacctg
    98041 ttggaactaa catataagca atcagtccca tgctgatggt aaagaagatc gtgttcaata
    98101 ctaaacgcat ctttacattt ttcactttgt tttgcaataa agctgtcagg cctaaagaaa
    98161 gcaatgtttg gccgccacca aaaaccacat ccatgatacc aaaaccaaag aaggcattat
    98221 agacgatgac cccgcctaaa actccccaaa gcaatttacg gttaaagaca actaaatgat
    98281 tcaaactttc tgaaatacga aactggatcg gccctgagga tacaggcgca actaaaatag
    98341 ttaacgctag ataaagagcc atgatgatgc catttacaac gattacggat aaccgttgtc
    98401 tgcttttcgt tttttgcatt ttctctcctc ttttctccta gtttttttaa cgcgggatgg
    98461 ttgatgaacc gcggttatgt gaaacaaaca ataattataa cagacttttc atttatttca
    98521 atccgtctta tctgctttta aaaaagcaaa agcttaaaca atgtaaacgt ttgctaaaaa
    98581 tcgtgggata tggtataaag taagtgtaag gggtcataag aattcccagt aaagcagacg
    98641 aagtaggatc tgcaagaaca gaattgttgt gaaacttaaa taaataaaaa aggatgtggg
    98701 aatttgagca acctcttact agagaacggt ctagcaagca gctgaagatc taagtggaca
    98761 tgccgaacct tggaacttct ccttacgtaa gtaatggatc atgcgcttgc taggcttttt
    98821 tgtgtttttc ggtcttcgga cctttttcat tttcctagac ttctgctata ataaccaaga
    98881 attaattttg taacagattt ttttgaaaaa acaagtttct ttcattcaaa aaatagaaaa
    98941 agcttgctaa ttattggtta accagcaaac aggagtatta aaatatcttg ttttattgaa
    99001 tagcaggagg aaatcatgaa attccattat catatattga tcaatccatc ggcaggcagc
    99061 ggaaatggct ataaagtagc agaaagaatt ttaccggtat taaaaaataa gcatattgac
    99121 tatacacttc attatagtga atacaaagga cacgatgctg agattgctga aactttggca
    99181 aaagaaacat tgattccttg gatagaagaa gaacagaaaa caatcgatac tttccccctt
    99241 ttgatcatcg taggaggtga cggcacctta catcaggtac ttgatacttt ctatcagatg
    99301 gaagtagaat tcccagttgc ttatattcca gcaggttctg gagatgattt tgctcgaggg
    99361 gcaggccttc caaaaaatcc caaaaaagga cttcagctga ttttagcagc tcaatcacca
    99421 gaaaaagtcc acataatggc ttatgaagaa aaaataagtg aaaaaaaagg aatagctgtt
    99481 aataatttcg gtataggatt agatgcagct atcgtccatg cgacaaatca ttcttccaca
    99541 aaaaagcgat tgaacaaata caacttagga tcattttcgt atttattctc tattctccgt
    99601 gctttattca ctcaaaaagg atttccaatt ctggtagatg caggaggaaa acaattaagt
    99661 ttttcaaacg catttttatg tacagcaacg aagcatcctt tttttggcgg aggaatcgcg
    99721 attgttccaa ctgctgatgc gtctaaacca gtcattgatt ttgtcgtggt cgaacgaatc
    99781 aatttcttta aaatcttgtg gctcattctt ttacttatac agaaaaaaca attgaaatcg
    99841 aaatatttcc atcactacac aacaaacaga ttacgtatcg tttcaacaac accgcaacat
    99901 ggtcaagaag atggagaaga aatggaaaaa cgaccttttg atatcacaat aaccacaact
    99961 aaacagttgt tttggtgtta ataaaagagg ttttgtcaga agctacatct ggaacaccgt
   100021 ttattcggaa aaaaggactg tgacacgact tttgtcacag tccttttttt actatgcagt
   100081 taattctttg cccaattggg ttgccatcga tagtttcttt ctttacccaa aataaattgg
   100141 atcattgaaa acaccgcagc aaaagcaact aagacacaac cattgaacca aaaagattct
   100201 gcaaatgttt gattgtaact gagtgtttca ctgatcaagt tattattttg aacaaaccaa
   100261 tatgttggtg tgaatgccgc tattttgcta accatttctg gcaagtattc tgctggtaca
   100321 aacaccccac cgataaagca actgcctgtg ataaaaatat ctttgatccc accgctggtt
   100381 tctgagtttt ttaccaatga agtgatacaa gccgaaaagc taatgatcgg caataaaaac
   100441 aagaaagtat ttaaaatatg ataccatacc gttatatccc acgaggtgtg gatcactaac
   100501 agaaccatta gaagtaagaa gccactgaac aacagcagcg agtaactaat caaactaaag
   100561 gttactttgc gattcaagtt tcgtttggta atgggcgcac tctggtttcg tttactgatc
   100621 tctttgcgat taaatgctag attgatgacg ctgaaaccgc taaaaatgga tagaaacaac
   100681 ccataagaca agaaattaaa ggttgtgccc gtcaacagct ttttcatccg ctgactatat
   100741 cccgcactta gctcaacttc tccagtaacc gagagtgcca tttgtgtctg ttccatagct
   100801 gcatcgattg ttttatcttc ttcttgaaac agaatcagtg tttgcaaaaa ggtgttcact
   100861 tgctgtgtaa caactgtttt agaaaaggca tctgggcgac tctgtatctt gatcgtcggc
   100921 atctttccta cttcgacttg ttcggtaaag tctgcaggca gatgtaagat aatgtttaca
   100981 cgattaaaat aaagagcatc atcgatttct ttttgtgagg ttccatccaa tgtaacgact
   101041 gtttccttgt cattcaaata tttacgaagg ccatcgacta caggcgactc ttcttcacta
   101101 atcaaggcga ttttcgcatc ttgcagagag gtattttcaa catcaatatt ttgcgcaaaa
   101161 aagaatgtgg caacaacagt gataattaca cctatcagta aattcgattt atttgcttta
   101221 agcaatgtcc aaatcgtttt ataaagcgtc ataacgcacc cctctttcca tccaagcatt
   101281 tcctaacgca aaaaggaaaa taaatccgat caaccataga agattggtat aaaaactagc
   101341 caaatcagtg tagaaataaa gtttatacaa actttcgctg atcaagttga cgagatttaa
   101401 ttgaccaaca atcggaatat gaagatcaat ccaatacttc acttgttccg accccatcat
   101461 accagcaaaa aagctcatcg caatcgtcac tgaaatcaag atgctatcct tttgcaccag
   101521 attcattttt ggtatcaaat taccaaccaa tgtacctaac aaaatcgcac acaacgaccc
   101581 cagagcggta acaatcatca accattgcca acgttcacca aagtctactt gatagataaa
   101641 acgaaagaca gctaacataa tataaatctc tgtcaaaaca atcgtaaagc ttgctgccaa
   101701 attagcgatt gaaactaacg attgctttct aggaatcaag gacaagcgaa taccatttga
   101761 cgattgattt gcttgctgat cctgtacatt gcggaccccc cacatcgtcc cgtagagaat
   101821 cgccattcca atcagagtga agaaataaaa acttttgaaa ctcatattac gacctgcatg
   101881 aacttcttga aaagatactt cttgttcaaa aacagtcatg atgggcgcga gatcaacgtt
   101941 ctccacttct gccactttac tcgaaattat accaatacgc tgtaaaaatt gatccatgac
   102001 gtttttcatc aacgtctgac tcattcctgc ttgacccaca tggagcgaaa cagatgaacc
   102061 atcaatgaga taaaaaccag ccaaatcatc tgcatttagc ttttcattcg cttctacttc
   102121 cgatagttcc tgtacttcaa ataatggttt atcattgact tcgacttgtt ctaagactgt
   102181 ggtaaaattt tccgaaagcg ctgtttgatc cgctttgatt acaattccag tattaatcgt
   102241 ttcgagattg ccaccttgat caatctcgcc aaaggccgcc ataaacatca atcctaaaag
   102301 aattggaaag gccaatgtcc aaaacaacat ggatttattt cgcagcagta tttttgtgcg
   102361 atatttataa aaatgccaaa acattatttc ccctcctcta gtctctcaaa tccttgccag
   102421 taatctctaa aaagacatca ttcaaggacg cttctttggt tgctattttt ccgtaactga
   102481 tcttttcttc ttgtaagatt gtaagaatcg gcaacaatac tgtatttagt tcagtagttg
   102541 ttacttggag ctgacctttt ttataagcga ttccatcaga agctattgtt cgctgacaac
   102601 acgttttctg ggagtaatgg gatgtcgatc gtcaaacgat ccgccgtccg taccatatct
   102661 tttagagatt ctttggttcc tttagcaatc acctgtcctt gatccatgat cacgatctgg
   102721 tcgcaaagaa tttctacttc ttccatgtaa tgtgttgtat agacaatggt tgctccttgt
   102781 cgattcagct ccttgatact ttctaaaatt ttattccgac tttgggggtc tacagctact
   102841 gtcggctcat ctaaaaaaat taaccgcggc ttgtgggcaa tcccacatgc gatgttcaac
   102901 cgacgtttca agccaccact aagttctcct ggacgaaacg aaacatattt ttctaatccc
   102961 actaattgaa tcacctcttc aatcaaggct ttccttttct ctttttcgga aacatataaa
   103021 ccgcaaaaat aatcgatatt ttcttgcaca cttagttcgt caaagaccgc aacgtcttga
   103081 ggaacgaccc caatcattgc cttgacagca taattttcag gagtcattgt tgtcccgaac
   103141 aatttaatgg ttcctttgtc ataatttaac aaagaaagca tacagttgat ggcagtcgat
   103201 ttcccactgc cgtttggtcc taacagacct aagacttctc cttcttgtac ttgcagatca
   103261 aaatgattca atgctacaaa atctccatag cgtttgacta atttatcaat ttcgataatc
   103321 atcatgaaaa actccttcca aatttcttgt tgatctgact ataataaagt gcaagaaaag
   103381 aaactagtga cgattggcta aaccacacat gacatttgtc acaatgaagg agtctgctat
   103441 gcataaatct cggctactca acgaaactag ctttctactg gttatctcat tgcttttgct
   103501 ggtaagtcaa ggattcgttg ctatgcaagt tatctattta ttgatcgccg ttttattcac
   103561 tggtgtcagt tatttactgc ctacaaagcc aaattggatt ttccaagtta ttctatttct
   103621 tttatgtgcc tttttacctg atcttgtcct gtttctgcca gcgacgatgc gagtgatcgc
   103681 ccctgaagaa agccaccttg attacttgtt tttgttaggt tttttgttga tttcgacggt
   103741 tggtaatcat ccccccatca aggtcgcctt tgtcgtaatt ttgctgtttt tttcctttta
   103801 cttacgaaaa aaagatcaac gaacgaccga tcttgagaaa aagtacattg tctccaaaga
   103861 tactcattgg gaaaaacaac aagagttatc ggaacaaaat aaagcattgg ccctgtcaca
   103921 agaaacacaa ttagccttgc aaattgtgga agaacggaac cgaattgccc gagacatcca
   103981 tgacaatgtc ggtcatctgc tgtcaagtgc gattttacaa attggtgcgc ttgaaatgat
   104041 caatcaagaa ccaaaactaa aagaaccatt agaaaattta agtgccaccg ttcacactgg
   104101 gatggatcgg attcgtcaaa gtgtccatga cctccatgag acatcgatct cttttcaaca
   104161 ctccttagag tttctgatcg ctgattttcc ttcttctgtt acgattgaag gaaacttgtt
   104221 tgaaggattg aatgaaacgc agcaaaactg cttcttaatg gtcatcaaag aagccttaac
   104281 caacagtatc aaacatagtc atgccaaaac cgttgtttta cattttcgaa cgttgccggc
   104341 cttttatcgc ttgcaaatca cgaatgatgg caccagccca caaaaaaatt ctgctcccgg
   104401 tattggtttg aaaacgatgc gtcaacgtgt tcaagaacaa aagggacaag tccatatttt
   104461 ccaagaaaac cagcaatttc agttaacgat cattttacca agggagggac accaatgata
   104521 acagtagtca ttattgagat gatccatttg tgacgaaatc gttacaaacc attttagaaa
   104581 gcacgaaaga gatccgtgtg ttaggcattg gtcattgtgc caaggatgcg ctagtcttat
   104641 acgaaaccca tcgtcccgat gttttgctga cggacatccg catgcctaaa caaacgggca
   104701 tcgatgctgc caaagaaatt ttggctaaat ttcccaaagc catccttttg cttttgacga
   104761 cattcaaaga tgaagaatac atccgcgaag cattttccat cggtgtcaaa gggtatttaa
   104821 tcaaacagaa cttgcaagcg attattcctt ctgtcaaatc cgcttataat ggacaggccg
   104881 tatttggtaa tgaaatcatc gagactttca ctcaaatgat gaagaataaa ccgacgattg
   104941 atagtcatgc ttatgcttct tttagtgaac gtgagcttgc aatcatcaaa gaagtagctg
   105001 ccgggaaaaa caataaagaa attgcagatg ccttgtactt gagtgacggc actgttcgca
   105061 attacatcag ccaattacta gaaaagctag atttacggga tcgcacgcaa ttggctatct
   105121 atttttatca gcatttgcaa taagtcttat ctaacacaaa aaaacctgaa tgatgctcct
   105181 tcgcatcatt caggtttttt tcacatcttc tattcaattg tcccgcaaac catttcctca
   105241 cgattgaaag aatcaaggat tcgcagggct gccaggattc gttggattgt tcggcgtgtt
   105301 aggcggaaaa ataggcgcct tgtctaacgt tttttctagt tttgattctt cacgatcgtc
   105361 tcgttctaca tcaggacttt cattcaattt gaattctttt tccatctcat ctaacttttt
   105421 aaagtcattg ccagattctt ttgctaattt cgctaattta tcttcggttt ctttagccat
   105481 aaagtaacgc cccccttttg atttcagctt agcatatcac actgaaaaaa caaaagaaaa
   105541 cgctaaccaa cgatcatttt tagctatttc tcatctttaa aatcaagcat tttttgccgg
   105601 tataaaatcg tagggagaac tgttttccat accaatcatc ggatctacta actggttatc
   105661 gatcacttct gctgtaagaa cgaaatcttt agaaacagca ggttctacct cttctttctt
   105721 ttcttctcca acaaatgaag aaaacagatc tggttccact gtttccatta cttggttttt
   105781 cgtttcattc gtcccactgt catcttctac aggtagcttt tcttttacaa cccgtggctc
   105841 ttttgtatag ttcccatctt caaatggatc atttccgacc aaagaatctt cataagctgc
   105901 tagtttggtc cggagagtga tattcatttt atcattatcc atgatccttg atttcaacgt
   105961 agtcatccgg cttgctgatt cattcgctac acaagtgaca taggcttgct cttcccctaa
   106021 caaaatcaac agttccttac tgcgagtcac tgccgtgtag agcaaattac gctgaagcat
   106081 ccgctgatat tgatggacca tgggcaaaat aaccatcttg aattcactgc cttgtgattt
   106141 atggattgag caacaataag aaagagtgat tttattccat tcgtttcttt tataagtgac
   106201 ctcatttgca tcaaactgga taactaattc atccacttta tcttcagaat cttttgccaa
   106261 gatgataccc gtgatttctc ccatatctcc attgaataca ttcaattcgg gagtattgac
   106321 taattggagg actttgtctc ctatccgata aacggtgtcg ttccaatgta cttccttttt
   106381 tccaggtttc cctggattga atatctcctg catcatttta tttaacgcat cgatccctgc
   106441 aggtccccga tacattggtg ctaatacttg gatatcttgt gcacggaatc ccttattttt
   106501 cgctttttcc acaattttag agatcaaggg ttcaatttga taagcatcac ttcggaaata
   106561 ggaacgatct ttttgattct ttgtgaaatc ttttggcaga cgtccttctt tgatctcatg
   106621 ggcaagagga ataatactag aaccatcacc ttgccgataa atctgattga gttccatttt
   106681 gggaatttgt tcgatttcca aaagatcatg gagtacttga ccaggaccga cagagggaag
   106741 ctgatctttg tctcctacta agataacttg catattcgtc ggaatcgctt tgaataatgt
   106801 gttagccagc catgtatcga ccatagacat ctcatcaaca atcaaaagtc cgccttctaa
   106861 ttctttcgta ctgactgaag gtgttttttc ccgtccattc agccccagaa gacgatggat
   106921 cgtactggca ggcagacctg tcgtttcgtt cattcgttta gctgctcggc cagttggtgc
   106981 tgcaagtaga ataggaaaaa tttcttgggt atattttgaa ggatccaatt ccagtccgtt
   107041 caactctgca aaaagattga cgattccgtt gatcacagta gttttccccg tacctggtcc
   107101 tcctgttaaa ataaatagag gggaacggat tgcttcagcg atagcttgtt cttgcgaagg
   107161 tccatactgt atgccgaata ttttttcgat acgccgaata ttcttctgca cttctttttc
   107221 aggataatgg atttcttttt tacgactgag aaggcgctgg atcgaattac cgatccccca
   107281 ttcagaaaag tacaaactgt tttcgtaaag attagtctct tcttgttgta tctttccttc
   107341 ttcaacaagt tggataatta cagtagcaac ctgatcaggc tggatttcaa ttgggcgact
   107401 tgtttctaaa atacggatcg tttgctgaag caatgtctcc gccggtacgt atgtatctcc
   107461 tgtttgaact gcatgctgaa aaatctgatg caagatagct gctcgaattc ttctcggtga
   107521 atctgctgca ataccgattt gttcggctag attatctgca cgtttgaacc cgattccttc
   107581 tatgtcttcg actagctggt acggattttc ttcgatgata tccaaagact cgttcttata
   107641 ggcctggtag atactgaaag ctaactgact accgaacccg taacgattca gtcccatgat
   107701 cacttgatcc atcccgtggt ttagccgaat cgtctcagca agcatttctc tttttggctt
   107761 cgtcaaaccg gagatttgtt ttaataccga aggatcagca atgatttttt cgatagcatc
   107821 ttctcccagc aattctacaa ttttttctgc tgttttcttc ccgattcctg ggaatttttc
   107881 gctggaaaga tacgctacga tcccatttgc agttgttggc ttttcttgct catatctttc
   107941 gagtttaagc tgccttccgt atttaggatg atccactaat tctccataaa aacgataagt
   108001 ctcattttct tgaatatcgc cgaaacttcc ggtgactaca atctcttttt cacggtaatc
   108061 agctgtggtt tcactgatgt gtaccaaaag cactttgtaa aaattactag gattttgaaa
   108121 aaaaatcgcg gcaactgtac caacgaaata aggcatttct tctggctgca tcggaagccg
   108181 cctccttctt ctatagtaaa ggttctggtg ctgtttcagt tcctaaaaaa tctgtttggt
   108241 tccatacttt cagttcatat ggcaataatc tgcaaggctc ttcagtctct aaaatcgtca
   108301 aactactatt gaacaatcca cccatttcac gcaactcact tagctctttt cctgtcatcc
   108361 attgaatggc tgcagttaaa gaagctccat gtcctacgaa taaaagtggg ccatctttat
   108421 gttgggcaac cgcatctgct acaacagttt cgatacgtgt gattgccgat tcaatcgttt
   108481 ctccgtgaaa aggagaagga tcatacagat ctaaatgatt acgcaaattc ggcagattat
   108541 ccggatattt ctggtacatt tcatcgatcg actgaccttc taaagtaccc agccctagtt
   108601 ctcttagctt atctgtataa aaaatctcta ccggacgagc aagctctttg ttgatacctt
   108661 ctgctgtatc acgtgctcgc tttgctgtac tggaataaat tgctttaaaa ggaacatatt
   108721 ttaccttttt cccaaatgct ttgatttctt cgtaactttg tggcaaaagc ggagaatcgc
   108781 cattgctccc ttgaaaacgt ctttcctgat tccattgtgt cttcccatgt cgggtaaaat
   108841 atagttccat acgcagcaaa ctcctgtctt tcttttattt tactctataa taaactgtct
   108901 aatccagctt gtcattttca tagtgatgcg tcaattctaa attagggaat ccttgctggc
   108961 gaagtgcttc atacactatc attgcagctg tattcgataa attcaatgag cggacatgct
   109021 catcattcat agggatgcgt aaacactttt cttcgttttc acgcataaat gtttctggca
   109081 aaccggttgt ttcttttcca aataaaaaga agtgctcttc tccatcagca aaattttcgt
   109141 cactatatac tttatgggca aattttgaga tcaaatgtag tttacgatta cctaaaaatg
   109201 ttaaaaaagc ttctaaatta ctgtggtaag taatatttac atcattccaa taatccaacc
   109261 ctgcccgttt tagatgtttg tcatcagttg aaaaacctag tggctcgatt aaatgaagcg
   109321 gagtattcgt ggctgcacac gtacgggcaa tatttccagt gtttgcaggg attaatggtt
   109381 caaataaaac gatatgattc atcaggatca ttcctctcat atttatgttc gtttctattt
   109441 tctgacaatt tgatttttgc ataaaaaaaa acgtatcaac tcggtgtcag tcactgcgag
   109501 tcgttacgtt agtgaagctc ttctcactaa cttttatcag aacaggaacc tgataaaaac
   109561 caatgaaaaa acaacttgtt gctaatataa caccctcaac ttttttttgc aacctctact
   109621 cattaaaaac tgctagaaaa acgttttctc ttagttcctt ttaataattc tatgtcaatt
   109681 gtaatcttct tcaaaggatt cttatataag tctgctttga ttcgctcttc tacctgccat
   109741 tctaaaggtg acatggccaa aagatctttt tgattttcct ctggtatctc aaattcatag
   109801 gttacacgct gacgttcagt taatttcatt gcttcagcaa acttggctac tacacgttca
   109861 ttggaataac tctgtttttc aggttgattc ggataaaaag cctgacgtag ttcctttaaa
   109921 taattttctt gtggcaccac cttcaacact tctccatctt ctgagagtac acgttggaat
   109981 tcttggtaat gagaaggcga aaagatattt aaaaccgcgt tgaatgtttg atcagcaaac
   110041 ggcaaattgg tcaaatcagc tacacaccaa aatgcttcgg cagattgttc tgtagctgcg
   110101 tagactcctt cttttgaaat atcaaatcca acagcatttt gaatcttttt caattttgaa
   110161 agttcattca agaagctacc ttctccgcag ccaacatcta atagcgagac ttcttcaggt
   110221 aaatgctgcg caatagtctc aataacgggc tgatacatgc cagattggat cattctacgc
   110281 cttggaacga acattccttg atcgtattct gttttaaccg catgggataa aaaataaagt
   110341 gttccttttt tggaaaggtc aaaacggtga ttatttttgc atatcaagcc attatcagac
   110401 ttttttactt cttcttggca aaccggacag cggaacagct gatgattttc tgccaaaaac
   110461 tggcgtcctc ggtcaatttt ttttaacata gttccccctc atttctgttt tatcttaccg
   110521 ttagatgctc actttggcaa ctgctaaaaa tatgatacaa tgcctagaag aaagtgaaag
   110581 ataaaggaga agattagatg atcaaagaat tttgcgctga aaactacaca tctattcctc
   110641 tagcaattgc tagaggagcc gatcggatcg aattgtgtga caacttagcg gtcggtggca
   110701 caaccccgag tactggtgtg atcgaagaaa cgttaagtta tgctggggaa aaagatatcc
   110761 ccgtaatgac gattattcgt cctagagggg gcgacttcgt ctataacgat atcgaattga
   110821 aaatcatgca tactgatttg attgaagcaa agaaattagg gacggatggc gtagtatttg
   110881 gttgtcttac tccttcaggc tggctagacg aagaggcctt agaactattg atcgaaacag
   110941 cagaagggtt gcagatcacc ttccatatgg cttttgacag tattcctgaa gatcggcaat
   111001 tcgaagcaat cgattggctg gtagaacatg gtgttgaccg tatcttgact catggcggtc
   111061 ctgctgacaa aactattgta gaaaatttcc cacggcttaa agaattgatt gcctatacag
   111121 atggccgctt aatcattttg cctggtggtg gtgtcactgc agagaatgca gcacatgtag
   111181 ctaaagaatt gaacgtaagc gaagtacacg gaaccaaaat cgtggatctt cagttataat
   111241 cttataaaca aaaaaacatt tgcaacaggc ataatgctta ttgcaaatgt ttttgttttt
   111301 ttacataaaa tagcccataa ataaagaagc aatattgaaa taaatcagta cactcgtcaa
   111361 atcgctcaaa gtcgtgataa agggaccgct tgctactgct ggatcaaatc ctagacgatc
   111421 cattagcatc gggattaaac tacctgcaag attcgccact gtgattgcaa atagcatagc
   111481 catccctatg acaaacccca agataaaatt atgtttccaa aaacctacga ttagaaaaat
   111541 cgtgatcccc gtaacagctc ctgtgacaac gccggtcaag acttcagcca aaacaagtcg
   111601 aacaaatcca tgatctttct catcagaaat cgcaagtcga cgaacagcca cagctagcga
   111661 ctgggttcca gcattaccgg cagttcctgt aatcagcgaa atgaagactg ctaaaatact
   111721 cgcttcactt accaagtctt catagtgact gattaaagaa gcggtcgaca tacctaaaaa
   111781 caacagagtg atcagccaag gcaaacgtcg agacgctgcc tttactggat tttcattaat
   111841 ttcttccaca ttgaccccgg caagtcctga ataatcgcta gcagcttcat catcaataac
   111901 gtcgatgata tcatcgactg tgacgattcc taacaaatga tcatcataat cggtaacagg
   111961 aagagctaag aagtcataat ctctaaatgt ttgtgccaca tcttcttggt cgtcgcctac
   112021 atgaactgaa agcactcgtt cgctcatcag atcagaaatc attgcgtcgt catcattcac
   112081 gattaggtcg cgcagagaaa taacccctac tagctgacct tcttgattaa cgacatagat
   112141 gtaatagatt gtttcagcta catctgcttc gttcttcagc acgtacatcg cagagcgaac
   112201 agtttgattg gctacgatcg aaacaaattc agttgtcatg atcgcgccag ccgtttcatc
   112261 ctcgtaatgg agaagttcct tgatttcact ggcatcgtct gccgacatca aacttaaata
   112321 tttagcaatt tgctttttat ccagcgtatt aagcaagtca acagcattat ctgtatacat
   112381 ctcagaaagc atatcagctg catagctagg acgcatttca tctaggtatt ctttcatatg
   112441 ttcgttgtct tcttcaatca catcgaacat atccgctaat tctttaggcg acagatagga
   112501 atagatcagc tgcctgttct cttctgtaag agattggtag aattgcccct gctcatagat
   112561 atgcatctct aaaaaactgt ttctgaatgc ctgaatatta ttttccctta aatcttgagt
   112621 caactgggca aatctttcct ctaattcttg attttcatcc aaaccaatct cacctcgcct
   112681 tattcttcaa accgtctcac aactgcctcc atgtctgcgg ctaaaggctg cttgaactcc
   112741 agcaactctt ctgtaaatgg atggtaaaaa cgcagatcat aacaatgaag ggcttgtctt
   112801 tttattccca gatccattcg cccgccatac atatcatcac cgagcagggc acagccaatt
   112861 gcggaaaaat gaactcttat ttgatgtgtc cttcctgtat gcagctggat atcaactaac
   112921 gcgatttctg ttagtcgctt ctctatccag tactcagtct gtgccgaacg tccttcatca
   112981 gagaccattc gcttcaatag cgaagaataa tctcgggcga tcggcaaatc gatatgtcca
   113041 tgtgccgata aatctgaaag ccttccactg actaaggcct gatatttttt cacaaacttc
   113101 ttttcacgaa gttgcatatc taattttgcg tgcgcaaatc catgctttgc aaaaagcatc
   113161 aaaccagatg tatcccgatc tagtcgcgtc accacatgga ttacttggtt ttcgtaacct
   113221 tgttttttat aataagcctt tacacgatta gccattgtcc catttggatg gtattgggca
   113281 ggaatagacg aaacgcctgc tggtttattt actaccagaa cgtgttcatc ttcatacacg
   113341 atatcgatcg gtgtttcatc caaaagtacg gtttcatgtt ctccttcagc aggaatcaca
   113401 atggttacct tatcatcctt agctagagaa aacaagacat tttctacttg atcattaact
   113461 ttgatttgac cgccttgaaa ttttattttc gctaacagac cctttgagat ccctttttct
   113521 tttaaaaaat attttacttg ctgagaatga tctttctcat aatcccatgt aaactgcata
   113581 tcaatcctca ctaataaagg catctttcac acgatgccaa aaatgcatat gtcgataaga
   113641 agcaaaatgg atccgttctt ctgctattcg ataataaatt gagcggatat ttgcttttgc
   113701 gacattcaat tgatcaaccg ttacaagata atcttctgta ttttccaatt ttatttctag
   113761 ccattcatca tgggcaatca cgatcggaga acccaaagta cgaaacactc gattattcag
   113821 tgaagcaatc tctgccaact gaaaggcatt gatactagga tggatcacag caccgccgac
   113881 acttttatta tatgctgtcg aaccagtagg cgtagaaatc gtcaatccat ctcctctaaa
   113941 actttcaaac agctcgtttt tgatgtatac atcggctacc atcgtacgat tggcccgttt
   114001 aatcgttgat tcattcagtg ctaaaaaatg ctggtccggt gtttcatcca aataactgat
   114061 ccgaacatcc agcaagggat aactaacact ttgttcccgg ttcgttcgta agctgtctac
   114121 tagttcttcc agctcgtaat cccgccaatc cgtgtaaaac cctaaatgac ctgtatgcac
   114181 gcccaagaaa cgcacatcat tcagacaatg actgtagtga tggaacgccg acaataatgt
   114241 gccgtctccg ccgactgaga tgaccaattc tggctcatga tcatctcgtt gaatccctgc
   114301 ttgttctaaa agtgcgttca aacgttctgt cacttctata gtctttgctt ctttattatg
   114361 aacgatcgct actttcatcc cctgcctcct ctctttcgct ttctttcttc aaaagcgttc
   114421 gatagtagac atcatctgat tttcctcttc catgggagaa taaccgctgt gcttcttgga
   114481 tttcttcacg gatactggac atctcttcat ccaactgata ggcagcttct gccgcacgct
   114541 gaagtcgttc actcatttct tctggaaaaa cgccttgata tttataattc agcgaatgct
   114601 caatcgttgc ccagaaattc atcgcaagag tccgaatctg gatttccgcc aaaattttct
   114661 tctcaccgct gatcagctgt acaggatact cgatcaccag atgataagaa cggtagccac
   114721 ttgctttttt atttgtgatg taatctcgtt cttggagaac tttcatgtct tttcttttac
   114781 ggatgatctc aacaacttga tggatatctt ctacaaactg acacatgatc cttaacccgg
   114841 caatatcaga catttcttct tctaaacgtc ccattggaat atgccgtaat tgtgattttg
   114901 ttacaatact atcgactggc ttgactctcc cagtgacaaa ttcaatcggg acatgtcgat
   114961 tttgttcacg gaactgtttg cggatccccc gcagtttcac tttcaattct gatacagttt
   115021 gttcatatgg tgctaaaaat gcttcccaat ctcgttccat agctgatacc tctacttcat
   115081 taacattcat tgtttattct accatatatg caaagttttt tcgtactctt gatttatgca
   115141 ttgaccaaaa aaagaaaatt aggcaaaata gacaaaaagg agtcgatcaa atgacacaaa
   115201 tgcttgaaat cgaatataaa tctatgctga caaagcaaga gtacgagata ttcatcgctc
   115261 actatcaatt aacagataaa gatttccgtg tacagactaa tatttatttc gataccgttg
   115321 atgaacagct gaagaaacaa aattgtggcc tacggatccg tttcgttggt catcaagctg
   115381 aatatacatt aaaaacacct gctgaaaaag ggcgtctcga aacaacggat acctttataa
   115441 cagaagaagc agaagcattt atcttcgaaa aacgtctgcc tcgttcaggc gcagtttttc
   115501 aaaaactttc tgatttgaat atcgatcctg cttcattaat ccaaaccgga aagcttacaa
   115561 caaaacgggc tgaattccct attgaagaag gacttttagc tattgatgaa agctggggag
   115621 acaatctaca cgattttgaa ctggaactag aggtaagggg atgcatctgt gggaaaaatt
   115681 gcttttataa attttttaaa acgtttttct ttaccttatc gtcctgctaa gaacaagatc
   115741 caacgtatgc ttgaagctaa aaattagaaa cctttcattt tcacaaggca cttgagttca
   115801 tttttttact tttttctgtt aagttatagg atgtgaaaga atctagtcac tagttgtata
   115861 gaatctattt tgggggagat tcatatgatc gaaatctatt tatttgttaa tcctttaggg
   115921 gaatactgtt tcgaaatgga acaacagtta ttacaattta tcgaagaaga gtacgggaca
   115981 ccatcaaaag aaaagatgca atttcgcttt cttcctttgg tcaatttgca gacaattggg
   116041 gatgtcatgc aacaaaaagg aatttctcag aacaatcttg aggaacgtaa tcacttattc
   116101 tcaatgactt attctgcagc attggactgc aaagcggcgc agtttcaagg aaagaaaaaa
   116161 ggccgccgtt ttttgatcaa attgcaagaa gcagtcggct gtaatgacat accatattct
   116221 caagaacttg ctgaatccat atttgaagaa atcggcggcg atttgaatat gtttaaagaa
   116281 gatcgtcagt ctgacttcgt taaagaagta ttcttttctg atcaaaaaat tgctcgggaa
   116341 atgggcatca caaaacaccc ttctgcagtc gtttacaatt atgcctgcga ccgtgatttt
   116401 ggtgttttag tagaagtaaa aggtacaagt agcctttgga gaatcacaga gctgtgtaaa
   116461 acaacagata actcatatca agtttttaat ggtgaacatt tacatacaaa tgattctcag
   116521 ttccattcaa gaactagcca tttacacttg ctttctaatt aaaaaaatac gtcgactccc
   116581 ttacaagaga gccgacgtat ttttttcgtt tctattcgag aaaatcaaaa atagaaagcc
   116641 ttataaacga tcgatcaatt cttctaattc atttagacgt tgttcaaaca tcgacattgc
   116701 atcttcaata tatgcagcct gtgtcatatc aactcctgct tttttcatta cttccacagg
   116761 ataatcgctg ttacctgctt ttaggtaagc caagtagttc tctagtgcct ctggttcctg
   116821 gtttagtatt ttcttcgcca gtgctgaagc agcagaaaag ccagtcgagt attggaaaac
   116881 atagtaatta taataaaaat gcggtatccg tgaccattcg aatttaattt ctgggtcttc
   116941 ttcgactgct ggaccataat attttgcatt caatttacca taactatcac ttaggtattc
   117001 actagtcaat ggcacacctt tttcatcttc cgtatgcatg aaatgctcga attcagcgaa
   117061 ttgtgtctgg cggaaaactg ttcctttaaa cccatccaag taatggttga gtacataagc
   117121 ccgtacacga gggtcttttt ctgtttccaa taaatactcc gttaggatat tttcattcgt
   117181 tgtcgaagca atttctgcta aaaagatgga gtagtcgccg tacacataag gctggttcga
   117241 acgagtgaaa taactatgaa cactatgtcc catttcgtgg acaagcgtaa atagctgatc
   117301 cagcgtatca tgccaattca ataaaatata tggatttgtg tcatagcttc ccgaagaata
   117361 agcaccgctt cgtttccctt tattttcgac aacatcgatc caacgttcag agaatgcttt
   117421 ttctacgatg gccatgtatt cttcacccat tggtttcagt gcttctaaag ctttttcttt
   117481 tgcttcttcg tacgtaaagg taattggagc ttcccctaag accggtgtat aaagatcata
   117541 catgtgcagt ttttccactt ctaataaacg tttccgtaat tccatgtatc gatgtaacaa
   117601 aggcaaatgc ttgtttacca cgtctaccaa agtatcgtat acactttcag gaatatgatt
   117661 attgctcaaa gacgcttctc tggcagagct gtaattacgg actttcgctt taaaattatg
   117721 tccttttata tgtgtgccta aagtagaagc aaatgtattt ctaaattgtt cgtaaacact
   117781 gtacaatccc ttaaatgctg cttcgcgcac ccttcgatcc gtgctttcta gcaactgacc
   117841 atacacgcca tgagataatt ggactatttc accattttct ccttcaatcg ttggaaaaac
   117901 tagatctgca ttattcaaaa cagcaaatgt atcacttgaa gcatcaaaga tttcacctgc
   117961 tccagcaaga agagattcct gctcagcaga taagacatgg gctcgattat ctactatttg
   118021 ctggatataa tggcgataga cttccaattt tggttcttct ttgaaatatt gccaaatctg
   118081 gtcatctgac aattgcaata tttctggttc aaaccaggaa acggcttcac taactttcga
   118141 aaacagactg cttgctcttg cataaagcgc ttggtaatct gtatttccag tgtcttgatc
   118201 gtttttaagg tgcgcatata cataaatgac ttcagtttgg cgataaaccc tcaatacgaa
   118261 ttcaatcgca tttaaaaatt gagaagcgcc ttgatcaagt gttcctttgt gtttttcaga
   118321 ttgttttaac tcttctgata attccaaata tttctcatca aactcttggt cgcttgaaaa
   118381 gatcttggtc aagtcccaag ttaaattttc aggcaattct tctcgttttg gcaactgctt
   118441 tacttccatg aaatccactc cttttcttcc cttagctcta tctatcaaaa tagatcatag
   118501 tctaacatcc acatgtcaca gcatctaact tttctactca ttcatgtgtc tgcttccatc
   118561 aattttagca taactaaatc ttgttttaca tagaaaaccg attcctagcc tatttttata
   118621 cttactattt tttcaaagaa gacaagtgta tgcattcgtt aaaaaactgc tgatagacca
   118681 tctcttcatc aatcatagga aaaagccatt cccttttatg ttcttttatt tggcaaagcc
   118741 atgagttgaa atcaggaact ttctggtttt ccaaggcttc ttcgtacaac attcgataaa
   118801 gaaaaacctg ttcttgtaaa taaaagaaaa accgactttt ttgatagatc cacgatgata
   118861 gatgcaaaag atgtttatga cgcaagtagc attgttcttg tatggatact gtattctttt
   118921 gcttgtgaat aagttggcgt gtcagccatt tcttcccatc ttcactcact ttttctattt
   118981 ttttcatttg gttcatttta atttcgttac tagtgaatat ttctttaagg tccctactag
   119041 aaaaagtcca gcagctactg caaaaggaaa tatgccctga tacagtctct gtaatatgat
   119101 gatacaaata aagcttttgt ttcttgagat cagctttcca gcaatgcact cctctttttc
   119161 tattatagta gcagcaactt ttttctatca atgagaattg cgattgtcca agaaaagaat
   119221 taccaagtat ccaccatact tggtaactgt tattcaaata attttgggtt ctttcaataa
   119281 atctctggtg agacagtcta gaacattgga tttctattgc tagattcgcc aacaaaatat
   119341 ccggcctttg ccgcaacctc ggcaaatagg cttccaaaaa tactggttct actgactgtc
   119401 ccagccaatc catgaagcat tcctttaact gtaagtgctc ttttgattct ctttcactaa
   119461 agaccgaaca gttatctgat ttttgatggg caaaatgagc acattttttc tttccctttt
   119521 tcaaaatcac tctttttcga cagccacgac aataatattt ctttcctttt tctgcatgtt
   119581 tagcaaaaca gcacttatta tattcattca ttgcaagcag catttttctc cctctgaact
   119641 tatttacgtc taagaattta tttacacgaa aaaagagggc gtgaaaaagc tattctgcat
   119701 caagtaataa gaacagctaa acaaaaatag ttcccaatat ttttcgtttg gttgggcttg
   119761 ttaccgcaga tgcaagcttt tgaacacatt tatacgaaaa aaagactgcg acacaatttt
   119821 tgtcacagtc tcttactata atgctgattt atacaaaata aaatttcgtt cgctcgatag
   119881 cattacgcgc catcagacat tgtccatatt cattcaatgt ttctggtgta cgatcgctct
   119941 tttcagcaaa ctccaaaatt cgagcaatct gattctctac atccgcttgg ttgagatttt
   120001 ccatccagaa gtgaacgact aggtaatagc gctcttcgaa taaatacaaa tcagtccaag
   120061 cagactctag ttcgacatct gttgcaagtt ggatcacttg ttcaaaatct tcaaaagcaa
   120121 aagttgcttg tctttcctgt tcttctaggg cgcttccaga taattcttcc tccggatcgc
   120181 tgccaataat ctgctgacga agaaagtcac tcacatcttc tgaatcaaca gtagaatctt
   120241 ctgattgaga aatttcttca tccggaagat ttttactgat aaacagttct aatccgtctc
   120301 cttttggcaa aacttggaaa gtgacagctt cgcttcctcg gaactcctct tcgatatcaa
   120361 cttcttccaa aatactataa aagaaatttt cgatttcttt gtgattgcca agtaaatcca
   120421 aaaatgaaac gccccgttcc tctaaatctt catgaccaat tagtacacgg atcgtatttt
   120481 cattaatatg ttccatttcc attttgctac acctcacttt gccacaatgt ttaatataga
   120541 ttcattgtag cgaaatcagc ttaaatgtaa agaaaaaaaa tctcgctgtt aagcgaattt
   120601 aataaaacca gcggattttt caacctttca agctatctta tttaactata acatttttgg
   120661 cagacgaata ctatatagcc gacttttcag ctaattttcc ctctctattt ttcgtgcaat
   120721 catcatcttc tactaccttt ttatacatct aatcaagaat actttttgta aaaacaaaaa
   120781 aacttggaaa aactatcttt gtaatagtct tt
//
LOCUS       DADLIO010000003        85129 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.003, whole genome shotgun sequence.
ACCESSION   DADLIO010000003 DADLIO010000000
VERSION     DADLIO010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 85129)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 85129)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..85129
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.003"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            183..701
                     /locus_tag="JOX41_000251"
     CDS             183..701
                     /locus_tag="JOX41_000251"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAY6448023.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            829..1512
                     /locus_tag="JOX41_000252"
     CDS             829..1512
                     /locus_tag="JOX41_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HAY6448024.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1821..1894
                     /locus_tag="JOX41_000253"
     tRNA            1821..1894
                     /locus_tag="JOX41_000253"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1855..1857,aa:Arg,seq:tct)
     gene            2053..2412
                     /locus_tag="JOX41_000254"
     CDS             2053..2412
                     /locus_tag="JOX41_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HAY6448025.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            2535..4166
                     /locus_tag="JOX41_000255"
     CDS             2535..4166
                     /locus_tag="JOX41_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HAY6448026.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(4228..4869)
                     /locus_tag="JOX41_000256"
     CDS             complement(4228..4869)
                     /locus_tag="JOX41_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HAY6448027.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     gene            5151..5459
                     /gene="rplU"
                     /locus_tag="JOX41_000257"
     CDS             5151..5459
                     /gene="rplU"
                     /locus_tag="JOX41_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HAY6448028.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5486..5830
                     /locus_tag="JOX41_000258"
     CDS             5486..5830
                     /locus_tag="JOX41_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HAY6448029.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5843..6136
                     /gene="rpmA"
                     /locus_tag="JOX41_000259"
     CDS             5843..6136
                     /gene="rpmA"
                     /locus_tag="JOX41_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HAY6448030.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            6543..9377
                     /locus_tag="JOX41_000260"
     CDS             6543..9377
                     /locus_tag="JOX41_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAY6448031.1"
                     /translation="MAKRIDRIYMYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNS
                     SKDLNQLVREGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDT
                     KDIFAKIIGANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAH
                     HVIDEETELIVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLD
                     EIHRLPPEGQEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRI
                     PINIKLPAFEKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQL
                     KSNIQLVCARGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKIT
                     VAPNDTIMKIQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFY
                     KDHGFSFNADSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKK
                     INLGEERHTNDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLR
                     ANQASGRIGVVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNV
                     QEVDEGSGVILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDL
                     DMLHESLKNFRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNK
                     RQETELEVLALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVI
                     LDQLLMESELEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTT
                     GIGDEEYGFKINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLED
                     QIKVKVPIEEMYYLLRLVHNQLDKKEYTVP"
     gene            9568..10059
                     /locus_tag="JOX41_000261"
     CDS             9568..10059
                     /locus_tag="JOX41_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIB"
                     /protein_id="HAY6448032.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            10162..11151
                     /gene="manX"
                     /locus_tag="JOX41_000262"
     CDS             10162..11151
                     /gene="manX"
                     /locus_tag="JOX41_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HAY6448033.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            11184..11987
                     /locus_tag="JOX41_000263"
     CDS             11184..11987
                     /locus_tag="JOX41_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HAY6448034.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            12008..12922
                     /locus_tag="JOX41_000264"
     CDS             12008..12922
                     /locus_tag="JOX41_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HAY6448035.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            13005..13379
                     /locus_tag="JOX41_000265"
     CDS             13005..13379
                     /locus_tag="JOX41_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HAY6448036.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGNNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            13518..13763
                     /locus_tag="JOX41_000266"
     CDS             13518..13763
                     /locus_tag="JOX41_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAY6448037.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            13935..14999
                     /locus_tag="JOX41_000267"
     CDS             13935..14999
                     /locus_tag="JOX41_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAY6448038.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            15245..15670
                     /locus_tag="JOX41_000268"
     CDS             15245..15670
                     /locus_tag="JOX41_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAY6448039.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            15663..16112
                     /gene="nusB"
                     /locus_tag="JOX41_000269"
     CDS             15663..16112
                     /gene="nusB"
                     /locus_tag="JOX41_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HAY6448040.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            16209..17063
                     /locus_tag="JOX41_000270"
     CDS             16209..17063
                     /locus_tag="JOX41_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HAY6448041.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            17064..18401
                     /locus_tag="JOX41_000271"
     CDS             17064..18401
                     /locus_tag="JOX41_000271"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HAY6448042.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            18406..18630
                     /locus_tag="JOX41_000272"
     CDS             18406..18630
                     /locus_tag="JOX41_000272"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HAY6448043.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            18632..19522
                     /locus_tag="JOX41_000273"
     CDS             18632..19522
                     /locus_tag="JOX41_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HAY6448044.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            19531..20349
                     /locus_tag="JOX41_000274"
     CDS             19531..20349
                     /locus_tag="JOX41_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HAY6448045.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            20456..20905
                     /locus_tag="JOX41_000275"
     CDS             20456..20905
                     /locus_tag="JOX41_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HAY6448046.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            20923..22605
                     /gene="recN"
                     /locus_tag="JOX41_000276"
     CDS             20923..22605
                     /gene="recN"
                     /locus_tag="JOX41_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HAY6448047.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(22660..22776)
                     /locus_tag="JOX41_000277"
     CDS             complement(22660..22776)
                     /locus_tag="JOX41_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HAY6448048.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(22849..23805)
                     /locus_tag="JOX41_000278"
     CDS             complement(22849..23805)
                     /locus_tag="JOX41_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAY6448049.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            23976..24344
                     /locus_tag="JOX41_000279"
     CDS             23976..24344
                     /locus_tag="JOX41_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HAY6448050.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            24514..24945
                     /gene="mraZ"
                     /locus_tag="JOX41_000280"
     CDS             24514..24945
                     /gene="mraZ"
                     /locus_tag="JOX41_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HAY6448051.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            24966..25925
                     /gene="rsmH"
                     /locus_tag="JOX41_000281"
     CDS             24966..25925
                     /gene="rsmH"
                     /locus_tag="JOX41_000281"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HAY6448052.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            25930..26331
                     /gene="ftsL"
                     /locus_tag="JOX41_000282"
     CDS             25930..26331
                     /gene="ftsL"
                     /locus_tag="JOX41_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HAY6448053.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            26332..28524
                     /locus_tag="JOX41_000283"
     CDS             26332..28524
                     /locus_tag="JOX41_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HAY6448054.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            28550..29512
                     /locus_tag="JOX41_000284"
     CDS             28550..29512
                     /locus_tag="JOX41_000284"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HAY6448055.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            29526..30887
                     /locus_tag="JOX41_000285"
     CDS             29526..30887
                     /locus_tag="JOX41_000285"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HAY6448056.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            30913..32001
                     /gene="murG"
                     /locus_tag="JOX41_000286"
     CDS             30913..32001
                     /gene="murG"
                     /locus_tag="JOX41_000286"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HAY6448057.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            32016..33236
                     /locus_tag="JOX41_000287"
     CDS             32016..33236
                     /locus_tag="JOX41_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HAY6448058.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            33392..34717
                     /gene="ftsA"
                     /locus_tag="JOX41_000288"
     CDS             33392..34717
                     /gene="ftsA"
                     /locus_tag="JOX41_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HAY6448059.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            34740..35981
                     /gene="ftsZ"
                     /locus_tag="JOX41_000289"
     CDS             34740..35981
                     /gene="ftsZ"
                     /locus_tag="JOX41_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HAY6448060.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            35998..36675
                     /locus_tag="JOX41_000290"
     CDS             35998..36675
                     /locus_tag="JOX41_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HAY6448061.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            36689..37288
                     /locus_tag="JOX41_000291"
     CDS             36689..37288
                     /locus_tag="JOX41_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HAY6448062.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            37303..37590
                     /locus_tag="JOX41_000292"
     CDS             37303..37590
                     /locus_tag="JOX41_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HAY6448063.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            37639..38421
                     /locus_tag="JOX41_000293"
     CDS             37639..38421
                     /locus_tag="JOX41_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HAY6448064.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            38442..39149
                     /locus_tag="JOX41_000294"
     CDS             38442..39149
                     /locus_tag="JOX41_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HAY6448065.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            39411..42209
                     /gene="ileS"
                     /locus_tag="JOX41_000295"
     CDS             39411..42209
                     /gene="ileS"
                     /locus_tag="JOX41_000295"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HAY6448066.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(42258..43784)
                     /locus_tag="JOX41_000296"
     CDS             complement(42258..43784)
                     /locus_tag="JOX41_000296"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HAY6448067.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(43799..44446)
                     /locus_tag="JOX41_000297"
     CDS             complement(43799..44446)
                     /locus_tag="JOX41_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HAY6448068.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(44630..44959)
                     /locus_tag="JOX41_000298"
     CDS             complement(44630..44959)
                     /locus_tag="JOX41_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HAY6448069.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            45136..45864
                     /gene="sfsA"
                     /locus_tag="JOX41_000299"
     CDS             45136..45864
                     /gene="sfsA"
                     /locus_tag="JOX41_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HAY6448070.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            45880..46893
                     /locus_tag="JOX41_000300"
     CDS             45880..46893
                     /locus_tag="JOX41_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAY6448071.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            46893..48170
                     /locus_tag="JOX41_000301"
     CDS             46893..48170
                     /locus_tag="JOX41_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAY6448072.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            48233..50935
                     /locus_tag="JOX41_000302"
     CDS             48233..50935
                     /locus_tag="JOX41_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAY6448073.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYDQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            51087..51404
                     /locus_tag="JOX41_000303"
     CDS             51087..51404
                     /locus_tag="JOX41_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAY6448074.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            51434..51754
                     /locus_tag="JOX41_000304"
     CDS             51434..51754
                     /locus_tag="JOX41_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAY6448075.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            51862..53322
                     /locus_tag="JOX41_000305"
     CDS             51862..53322
                     /locus_tag="JOX41_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAY6448076.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGILPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            53390..53611
                     /locus_tag="JOX41_000306"
     CDS             53390..53611
                     /locus_tag="JOX41_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448077.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            53642..53824
                     /locus_tag="JOX41_000307"
     CDS             53642..53824
                     /locus_tag="JOX41_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HAY6448078.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            53824..54237
                     /locus_tag="JOX41_000308"
     CDS             53824..54237
                     /locus_tag="JOX41_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HAY6448079.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            54360..55541
                     /locus_tag="JOX41_000309"
     CDS             54360..55541
                     /locus_tag="JOX41_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAY6448080.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            55930..56003
                     /locus_tag="JOX41_000310"
     tRNA            55930..56003
                     /locus_tag="JOX41_000310"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:55964..55966,aa:Arg,seq:cct)
     gene            complement(56072..57211)
                     /locus_tag="JOX41_000311"
     CDS             complement(56072..57211)
                     /locus_tag="JOX41_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAY6448081.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(57510..58145)
                     /locus_tag="JOX41_000312"
     CDS             complement(57510..58145)
                     /locus_tag="JOX41_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448082.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(58258..58893)
                     /locus_tag="JOX41_000313"
     CDS             complement(58258..58893)
                     /locus_tag="JOX41_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HAY6448083.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(58927..59388)
                     /locus_tag="JOX41_000314"
     CDS             complement(58927..59388)
                     /locus_tag="JOX41_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4429 domain-containing protein"
                     /protein_id="HAY6448084.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(59518..59949)
                     /locus_tag="JOX41_000315"
     CDS             complement(59518..59949)
                     /locus_tag="JOX41_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAY6448085.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(59967..60287)
                     /locus_tag="JOX41_000316"
     CDS             complement(59967..60287)
                     /locus_tag="JOX41_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAY6448086.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            60586..61362
                     /locus_tag="JOX41_000317"
     CDS             60586..61362
                     /locus_tag="JOX41_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HAY6448087.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            61377..61580
                     /locus_tag="JOX41_000318"
     CDS             61377..61580
                     /locus_tag="JOX41_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAY6448088.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            61596..61934
                     /locus_tag="JOX41_000319"
     CDS             61596..61934
                     /locus_tag="JOX41_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HAY6448089.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            61921..62100
                     /locus_tag="JOX41_000320"
     CDS             61921..62100
                     /locus_tag="JOX41_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448090.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(62143..62613)
                     /locus_tag="JOX41_000321"
     CDS             complement(62143..62613)
                     /locus_tag="JOX41_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448091.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            62700..63398
                     /locus_tag="JOX41_000322"
     CDS             62700..63398
                     /locus_tag="JOX41_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HAY6448092.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            63576..63917
                     /locus_tag="JOX41_000323"
     CDS             63576..63917
                     /locus_tag="JOX41_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448093.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            63910..64581
                     /locus_tag="JOX41_000324"
     CDS             63910..64581
                     /locus_tag="JOX41_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HAY6448094.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            64587..65279
                     /locus_tag="JOX41_000325"
     CDS             64587..65279
                     /locus_tag="JOX41_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448095.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGGEK"
     gene            65276..66025
                     /locus_tag="JOX41_000326"
     CDS             65276..66025
                     /locus_tag="JOX41_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAY6448096.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            66037..66306
                     /locus_tag="JOX41_000327"
     CDS             66037..66306
                     /locus_tag="JOX41_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448097.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDGTQLRNLAYTKLLFIDCVKGLQKHLNELEQV"
     gene            66469..66768
                     /locus_tag="JOX41_000328"
     CDS             66469..66768
                     /locus_tag="JOX41_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448098.1"
                     /translation="MDKKAAMQRIIELTYSEDWQEDKKIVAEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAKQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            66768..67070
                     /locus_tag="JOX41_000329"
     CDS             66768..67070
                     /locus_tag="JOX41_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448099.1"
                     /translation="MDELIAKVEQWAKDKGLDQADFSKQMLKTVEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLDFAYDEIKGRTGKMVNGVFVKSSDLK"
     gene            67110..67475
                     /locus_tag="JOX41_000330"
     CDS             67110..67475
                     /locus_tag="JOX41_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448100.1"
                     /translation="MIDAKQVQKQKDGMLMFEAYVLPFLNQFEVLECSASGEELEYVV
                     IRETKENVQKLNEFLCTINCWDMIAPGFLCPAMGEFLEYCRLEDAGTLDLAYLVYNYL
                     NINTDHLWFGTAERKWVVR"
     gene            68102..68284
                     /locus_tag="JOX41_000331"
     CDS             68102..68284
                     /locus_tag="JOX41_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448101.1"
                     /translation="MRATDPVIILEEAKFIWTHEEIEQARLLFSQGVKPSKVAEIMGQ
                     KILDVGLLLLHLAEKI"
     gene            68297..68491
                     /locus_tag="JOX41_000332"
     CDS             68297..68491
                     /locus_tag="JOX41_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448102.1"
                     /translation="MMIQLAGIQTGKIYFSGESKSEANQWLLKTYTNNKKLRKKYPDL
                     LLKDDQIMPEPMILTRKEGS"
     gene            complement(68524..68736)
                     /locus_tag="JOX41_000333"
     CDS             complement(68524..68736)
                     /locus_tag="JOX41_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448103.1"
                     /translation="MNINNLVKLVEQRFKESGLEQLKKDNSPELFSNFTEDDIPTLKQ
                     LKYYSDYWTQTRENELNLEKLIIKKK"
     gene            68861..69064
                     /locus_tag="JOX41_000334"
     CDS             68861..69064
                     /locus_tag="JOX41_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448104.1"
                     /translation="MVKVREQFKIVSDEGNVYKIKIVNINEYREADHKYLVDLYMNDK
                     YLGEGFCGDSLFDDERILKEETE"
     gene            69061..69333
                     /locus_tag="JOX41_000335"
     CDS             69061..69333
                     /locus_tag="JOX41_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3850 domain-containing protein"
                     /protein_id="HAY6448105.1"
                     /translation="MIHELKILPEYFEAVTSGRKQFEIRKNDRDFKVGDQLILREYKK
                     YIKHELPGLTRPTFSYTGDSYKAEITYITDYMQKSGYVVLGIKGVN"
     gene            69334..69519
                     /locus_tag="JOX41_000336"
     CDS             69334..69519
                     /locus_tag="JOX41_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448106.1"
                     /translation="MKVYILAITEGTWMFPVGSGKIYKSKTAAYKAFEKYKKENGGGT
                     NAKILVADNWHEEGERN"
     gene            69506..69853
                     /locus_tag="JOX41_000337"
     CDS             69506..69853
                     /locus_tag="JOX41_000337"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448107.1"
                     /translation="MNVIDLPVHFRGTNYFYASNLIQKKMSKDERKILANFYLVLKIE
                     QNVFSERRIVWEKQNQRLRRKNDVWNKRQSRMERLRKNKKATPFEIAAQYYSTIRGGV
                     CEISLVKRLPRTR"
     gene            69813..70289
                     /locus_tag="JOX41_000338"
     CDS             69813..70289
                     /locus_tag="JOX41_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HAY6448108.1"
                     /translation="MRFHWLKDYQELDEQILYLKWNLNKSKLELNRWVCGDLANVRIE
                     KNSRTSSLEENIQKIENELELLIEQKEEMLLLIDSFSGIDNQIVKMKYVDQMSLEDIA
                     ESVGYSSSYVRQRHAEIRKTLNFLDEYEHRQADRLKKENEIDFYNSEKYKEQLSLF"
     gene            complement(70435..71163)
                     /locus_tag="JOX41_000339"
     CDS             complement(70435..71163)
                     /locus_tag="JOX41_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HAY6448109.1"
                     /translation="MRGVLMLQEVNIKYRDRQNTETIYLPNSCPHCGNIMTPYVYFGV
                     SSYSAFDNDRIFGVLVQCINDECNKFYSLQFINTFNEDEGYSENILIKDYYRPPIKID
                     LPENIEKVSPTFVDIYTQATQAKSEQLEQIAGVGYRKALEFLIKDYAISKNSEDEDKI
                     KKMLLGKTIENYLNDFPKLQRLAKAATWIGNDETHYVRRHTNKDVHDMDAFIKSAAQF
                     IAADYDADLADQFINGNNFMPTTN"
     gene            71211..71489
                     /locus_tag="JOX41_000340"
     CDS             71211..71489
                     /locus_tag="JOX41_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448110.1"
                     /translation="MNDFHEAVLSIEVESSLAKVYKKAIEAENSPYRENWNGNHAHVQ
                     VENDDYRTGMNTLVISLLSHTLPNLQETIEWYERMGAKVIRTNYKGEN"
     gene            71491..71877
                     /locus_tag="JOX41_000341"
     CDS             71491..71877
                     /locus_tag="JOX41_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448111.1"
                     /translation="MAMIKIRTSISGTEYWDSEKKRTVVVPKDQEPNFEVKEEKGILS
                     DGKSFVAVNGELIAHSSEILDSDGNTAANFDGDEATNDQSTEDTDELDNMTAKELRAY
                     AKKHGIDIPGAIRAKGDIINLIREVE"
     gene            71874..72254
                     /locus_tag="JOX41_000342"
     CDS             71874..72254
                     /locus_tag="JOX41_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAY6448112.1"
                     /translation="MKYCQFDGCTNKIAKGIYCTEHKRSSRSRKKKQQAKSVYHHENK
                     PFYRTQAWKDMRQFIYEREGGHCQRCGQFIFGKRAHVHHIVPIKDNELLKLDPNNLML
                     LCSKCHPIVENETEDKKVFPSYFN"
     gene            72366..72818
                     /locus_tag="JOX41_000343"
     CDS             72366..72818
                     /locus_tag="JOX41_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HAY6448113.1"
                     /translation="MTTKAQRKAIIDEKVSAEKARILEIMNLSDLYTITLDPLIESYL
                     DIFEIYQHKYLLWKEKGFPETQKFTNKSGATNQSKHPLAQQVETWADKKMKALDLLGL
                     TNKAKTGRLIAGGSTARKDEEITRPEVKPVDELAAHRNKWRKKAGAEK"
     gene            72815..74542
                     /locus_tag="JOX41_000344"
     CDS             72815..74542
                     /locus_tag="JOX41_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HAY6448114.1"
                     /translation="MIEPGVNYADLFAKEVRKKPKKYPKTVRLAIDRWYQWKKRKDIW
                     FDVDRANEMMDWVESFIVHTKGEMVGKPFLLEPWEKFIYSWIYGWVKENEKGQIVRVT
                     REAYVQIPKKNGKTLIAVGSLGYAMYGEGALSVDCYACASDFAQAQYAAKPFAVTILN
                     NPILLEGTKIFRGPKGTVSSITYDYIHEDMAYSNKFIVQTKNIDNIEGSNPYFVLNDE
                     LHKQEKMEQYDNFKSAQISLPQPLMFNISTAGKGSSSVGMRVYREAKEVLKRDDNDSN
                     FVLIYEPNKNYDWTDRKVWEMCNPNWGISVDLSALESAFKTAQRSAHSKAEFLTKHLD
                     VFVNGADNFFEQDQVEPCLVTTQELGDLSGEPCYIGLDLSRTRDLTCVSLNFPTWDED
                     GKAVLKVKQLYFIPNEDLEFREKEDNVPYSDLAEQGFVEFCDGKMIDQDQILQYIEDC
                     MNLYDIQQVNYDPAMSDKLVEKLENLGLECVEVAQYPKVLNAPFDDVERLFYEKRIQF
                     DNPLFLYCTLNVVAITNINGQKAPSKRQSKKKIDGFVAFLCGHKETMNQMTDIDSDEL
                     DDYLSSIYR"
     gene            74606..75793
                     /locus_tag="JOX41_000345"
     CDS             74606..75793
                     /locus_tag="JOX41_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAY6448115.1"
                     /translation="MEKRGYIEDIFGHYTRYGQRYVTDSSIMESSDVYELVQDISNQV
                     ALATPIVIGPDGNEVKDHHLLNILKSPNDYLTGFEFTKLETNTLLINGETFPLTDRDQ
                     LHLAYGVTTKINERLQEEFEMNGQKIPGQMIRHIKNIGTDSLKGAGIIDLARNTLEGV
                     LSAEKVLTDKYTKGGLLAFMLKLDAHINPNNSAQTKIVKAILDQLEGTQNESDHSVKM
                     IPLGKGYSIETLKSPVDDAAILNYLGVYKKDLGKFLGINVDTYQSLMKTDIEKAMMYL
                     HNKAIKPILKNKSEHYTALFFMPNSGYRVEWKINILDFVPYSTKTNIGYNIVRTGITS
                     PDNVAEMLGFPKQNTPETQAIYISNDLSRIGQKNATDDSLPTNDQDLKGGDGNEEEGN
                     SHD"
     gene            75759..76334
                     /locus_tag="JOX41_000346"
     CDS             75759..76334
                     /locus_tag="JOX41_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HAY6448116.1"
                     /translation="MEMKKKEIRTIDITNLSTRSDEETHTRTISGYAAVFNSQTLLWD
                     DLSEVIVPGAFSKAISNSDVRCLFNHDWSNVLGRTKSGTLRLEEDERGLKFEVDLPDT
                     TVARDLVKSMERGDINQCSFGFVPTEETWDYNSEPMLRTIHEVELYEVSIVPLPAYED
                     TEAALRSRDELEKNVEERKKLIKKINQALEA"
     gene            76347..77711
                     /locus_tag="JOX41_000347"
     CDS             76347..77711
                     /locus_tag="JOX41_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAY6448117.1"
                     /translation="MDKELLKKMKARREQRLTELREKVESGELREADLEAVKEEIDSV
                     IDELNGIKDELGADSGTDETDDNTDDQSNSTDSDESRSGEDNDQEEDSDSEDSSENRS
                     GMITQQQRDGLLGSIKNGLEARAKMTKKQKDQQLRKAFANFVAGNISEAEARALGIEA
                     GNGSVTVPEVIASEVITYAQEENLLRKYGTVVRTSGDVKYPILVKKADANVNKKERST
                     DIAETAIQFDEILLNPAEFDALATVTKKLLKMSGVPVEDIVVEELKKAYVRKEINYMF
                     NGDDAGNENPGALAKKAVAFKKPLDLTASGAGQKLYDALIEFKNTPVTEVMKKGRFII
                     NRAALTAIEKMKTDDGFPLLRPFTQAEGGIGYQLVGYPVDWTDAADKKGEPDTPVLYF
                     GDFSAFKIQEVIGALEIQKLVEKFSGKNQIGFQIYNLLDGQLVYSPFEPAVYRYEITK
                     PVGG"
     gene            77713..77994
                     /locus_tag="JOX41_000348"
     CDS             77713..77994
                     /locus_tag="JOX41_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HAY6448118.1"
                     /translation="MEEQTKELSLEEKFKSHIHFEEGMDDSLLSFYLNMAKDYVKTAT
                     GGQQEYLILMVAGIAYEYRVSEDELDKAMNAMTPFIVQGAIQNAEETDQ"
     gene            77972..78298
                     /locus_tag="JOX41_000349"
     CDS             77972..78298
                     /locus_tag="JOX41_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HAY6448119.1"
                     /translation="MPKRQTNNLRWKAELLDIKTGTDGNDRPTTIYEFKRLIFYEELG
                     VTSQEKYLSQQAKTDVVRRIKVRWDKSITEKLSALKIDSVTYNITRIYTNPDAREMEL
                     SLAYVD"
     gene            78288..78626
                     /locus_tag="JOX41_000350"
     CDS             78288..78626
                     /locus_tag="JOX41_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448120.1"
                     /translation="MSISFDELKTALKSTKLAVFRDKARLGTMYPYIVYSNVSNSKKM
                     ASGKVYKKLPYYQVSFFTLGTEQDLVVIEQALQNAGIPYSDFTGIQGDENDDTVTNYY
                     TYVRCVENAK"
     gene            78616..78981
                     /locus_tag="JOX41_000351"
     CDS             78616..78981
                     /locus_tag="JOX41_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HAY6448121.1"
                     /translation="MPSNKNGFSEISDYLGNLSKVDPKKLSLESLEEAANFYLKQLLP
                     NIPKSLLKKKHMRDQIKVVVENDQVKVQFEETAFYWRFAENGTTNQRAQHFASGTYEQ
                     NKEKIEEIMTRKILDLWEG"
     gene            78988..79614
                     /locus_tag="JOX41_000352"
     CDS             78988..79614
                     /locus_tag="JOX41_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAY6448122.1"
                     /translation="MGKQDTFYFEGLDDILIAMMATPDSVGTAPTYSEVLRLPIATKI
                     GVKGNGTALEKWASSKMFRRVSRETKHELALDHVGIPIEVMDEIKGLVAKSGVTFSKN
                     TAREFPYFAFGFIGNIENGGKKAVWYPNTQLSNVIDEEYATAEEETKIDDVTANLVSI
                     GLKYNNVMYASFDSNRDGASLELFNKFIAQPVYDEEQWKTLAKVGGAG"
     gene            79614..80078
                     /locus_tag="JOX41_000353"
     CDS             79614..80078
                     /locus_tag="JOX41_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448123.1"
                     /translation="MARLSDYGIHVEDLKNSAVVIIQGAEFPISFTMQTMEFIADVYG
                     GDYSQFESDMNAMLSKKEGQISSANLSPSDLKIMRALIYAMLRTGGLEEDPETIFKFL
                     GMSGEVLSAYSTCMEIFASQTFQVEDLKKSKKPQDFQKAQAKRKKNKKNRKR"
     gene            80273..82582
                     /locus_tag="JOX41_000354"
     CDS             80273..82582
                     /locus_tag="JOX41_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HAY6448124.1"
                     /translation="MAGKESDVVLNFKTNGEVSYSKTIKEINKEMNLAAAEYKNQVSA
                     MDKDATQTEKLRAAKQKLEKQLGLAEQRSQMLREEYEKSVKETGEYSAESEKLYKQLL
                     NSETGENKLRTALEQTNDALKEQGDVSVDTAKKLQKIEETGEKVKGVGEKMSVGVTAP
                     IVAAGAAGLAAFGEVDEALDTIITKTGATGDQADRLSQSFKNVGSNTHLPLQTVGEAI
                     GEVNTQFGFMDKKLEDSTNYLLQYAEINDTDVSQSAISARQAIDAYGLEYDDLNSVLD
                     VTTKTSQNTGQSVDDLMQKAIDGAPQIKQLGLSFGEGVTLLGQFEQSGVDSSAALSSL
                     SKATVAYAKDGKSLSQGLEELQDKVKNAGSETEAINAAAEVFGTKGGPRMADAIRRGT
                     LNLEDLAKTAGESGGAVGDTFDATLDPIDQADQAMNNAKLAMADVGEAVQVSLLPFFE
                     KATSLLQEFSKWWGSLDQDTKNWIITIAGIAAAVGPVLIVLGSLMGSVTKIVGEVKSF
                     IGVWQGLAGLFGMSGGWFALAVIAIGALVTGLIWAYNNVKWFHDGVNSFFKGVSDVAV
                     EIFNFLSGYFGGFFDGVIANFNNFYNAGKRIFSGFLDFITGVFTGNWSKAWQGLVDIF
                     GGIFDGIVAVGKAPINAMIGLINGFIGGLNNIKIPKWVPGVGGKSFSISKLPYLAQGG
                     HLINGQAIVGEAGPELLTAKNGKTTVTPLSDEEKRKGISGRVSGGSIEQHIHIGKVDA
                     NNPSELDRMNRKFAKANKQAIRDLGGVPI"
     gene            82594..83298
                     /locus_tag="JOX41_000355"
     CDS             82594..83298
                     /locus_tag="JOX41_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAY6448125.1"
                     /translation="MNPDEPNFIWKNRNAVIDMNCIIEAELPDIMPNKRYETYTIQGR
                     SGELTETFDDYEPFDLEIEGITIPHSKLREVKRWLTGKSQLITHNDPDKYLEAICSMD
                     KEVPFENEWGFFYTFDVTFRCQPLKRKIGEAPKIFHSSVMDIFDHGDEIAHPYLEIES
                     NGGDITIAVGDKSLTILNTLAATIVVDTQLGKAIQEGLNLFTRGDWPVLQPEWNQVKI
                     SGKFKEVRFWNRSVYL"
     gene            83295..>85129
                     /locus_tag="JOX41_000356"
     CDS             83295..>85129
                     /locus_tag="JOX41_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448126.1"
                     /translation="MTQEFIYAYKKMPDDLSVNGASLVDWEDLPEINRVLNGQYRFYG
                     NYSRSGQYRSYLKKGNFIKAKVPDGSWQYFEIYNVKKNLTSVSVTARHIGFMANKNFI
                     VKSFTDNGNGSQIMTNLKNSLAFDQKFNYLSNVGTTHQFTARQVAPVEAIIGSNNGNQ
                     NLTGVTSAELDMDNYDLKLVKQIGSDNGFRIDFGINLEAIEEEIDEESIVNSLYLVGG
                     VPDNDYDEDKEPIEYGYLEIDGVTNENRRIAKRENGDCKTVDELIKWGKTLFDNDRIH
                     EPKATHTVSMVALEHTLEYGDMYQELASLHFGDVAHVRAKELDIEIKERMVEYTYFPT
                     LGKYKDIVLGNDLSLYTSAVNTQAQELKKKIDNRTETLVQNVLNATAWITGNSGGHVV
                     FRPEKAPSEILIMDTPNVANAKRVWRWNLNGLGYSDNGVNGPFGIAITSKGEIVADFI
                     KVGTINAEVFETSFNAYGDVLKLVKGTLQIWNENKKIMELTKKGMEFWNRKESIGTIG
                     TTDSAGNPFPNAVTPTPLEENSLVIRTNGDGKYILISPTAEKGFVLLGNGKAYYFGDL
                     DIQGKLTVRGKEVIPGQNGGPSGGGETPGGYPDELKTDAEKRAWR"
BASE COUNT        28701 a        14002 c        17881 g        24545 t
ORIGIN      
        1 gttagggtaa acgtttttta aactaacgtc aattatttat aataaaaaat gagataaaga
       61 tgaggaaata gaattagaaa catataatta ttaaagggaa acatttttac agctataatt
      121 tgaaaaaatt tatcgttatt atatgattaa gaaggattga ataaagaaag aagttgaaaa
      181 cgatacctga ttacaaaaaa ataactttta taagttctat aacgttgatt atatttttaa
      241 ttcttattct tctcgtcgtc ttggttcccc gaatttttgg tttgactcct tatattattg
      301 aggacaaaga aatgagtcca tattatgcac aaggaaatct gatatatgta cgaccgaaaa
      361 atacaaatga gattttagtc ggagatatta ttacatatta tgaaaattca ggaaaaaaaa
      421 tctcgacgcg tcgcgtaata gccgttgaaa acaaccacga agatttttat acaaaagctg
      481 atacaaagac ttatattgag cctggagtag taaaaaagag aaatattatc ggtagtccca
      541 tctttcagat tccatatatt ggactagtcc tttcaaaaac ggcatttgca tggattcagg
      601 ggttattctt tacgattgct ttttgcctaa caggaatcac agcatggaat acctttgtag
      661 agttgaaaaa gaagcggaga cgaacacaga aatttttgta agaatgttaa aaacataaat
      721 gtattccaga gatccaacga ctcttctgaa catgaaacac gagaaaacac tcatgcagct
      781 tgtagattta gtcagttgtt cgtataatgt gtgaagagga ggagtagtat gcgcaatgaa
      841 atgatgcatc gtcctgtagt caaagaagaa ctattggatt ttatgcgtac ccagcaaaaa
      901 aaattaccgg gtgagctagg caaactggaa gaagaagctc atgtagcaga agtaccagtt
      961 attccccatg aaacagttgt atttttgaaa tttttacttg gacagcttca gcctgaacga
     1021 atcttggaga tcggagcagc tatcggtttt tcatcaagtg tcatggccac gacaatcgga
     1081 gaaaacgctc atgttacgac aattgatcgt ttcgatgtca tgatcgagaa agctaaaaaa
     1141 aactatgaac gtctaggact gacagataaa gtgactttgc ttgaaggtca agcagcagat
     1201 atcttgccgg agttgtctgg tccgtatgac tttattttta tggatagtgc aaaatcaaaa
     1261 tatattgaat ttttacctga atgcttacgt ttgttaagaa aaggtggcgt tttgatggta
     1321 gatgacatct tccaaggagg aacgatcttg ctcccagatg aagagattcc ccgtggcaaa
     1381 cgagctatcc atcgtaaatt aaatgaattt cttcgtgttg tgatggatca tcccgatttg
     1441 acatcgacaa tcttgccatt aggtgatggt gtgatcttaa tgacaaagga atcagaaaca
     1501 atcgagttgt gatacatgat tatggcagcc tgtagataat cgattgaatc gagggctcaa
     1561 ttcgaacttg atgtaaaagt ttctatattt gtaagtcaat taaaggatac aggaaatcta
     1621 aataaacagg agtagcatga agtcaatgta gctcctgttt tcaattgata accttagaac
     1681 agctgaagga gaatgtctcg ttttaaaaga ttgatttagt agttgggcca aaataattca
     1741 ttatttgcta attaaataac tatttcgtat tgacagaagc aatttaatta tctataatta
     1801 ttgatgttcc gctgattctt gtcatagtag ctcagctgga tagagcatcc gccttctaag
     1861 cggacggtcg ggggttcgaa tccctcctgt gacgctaaaa aaccgttaga aactgaggtt
     1921 tctaacggtt tttctttgtt ttttgtgcca atattgtttg ttttcaaagg caaataaaat
     1981 aaaaaaacat ccttatcgag tacaattata aggagcaaaa aaataaaact catcagaaaa
     2041 gaggaagaag atatgacgat actatctaga attttagtga ctctagttgc aattgaattt
     2101 ttttatatca tgtatatcga aacggtgaga actgattctg acacgacaag tagggttttt
     2161 aaaatgagta aagaagagtt aagcagaaaa tctgttcaaa cattgtttaa gaaccaagga
     2221 gtgtacaatg gactattagg agtgggacta ctttatggag cttatctttc ttccgcatct
     2281 aaagaaatca caagtatgct attaatatct attttttttg ttgcattata tggcagtttg
     2341 actagcgatc gttggatttt actcaaacaa ggtgggctag ctctgttggc attgctttct
     2401 attttcttat aaatatagaa aaaataagaa tttatctaac aggaaacttt gtgaaaaata
     2461 ttactttatc tcatgaaata tgatattcta atgaatggta ttttagaaaa tttcatgaaa
     2521 aaggagttag ataggtgttc aaaaattatg tttcctcact aaaaaaagaa ttttcaggtt
     2581 atgatctttc aagatttcag aaagatcttt tggctgggat cacagtagct gctgtagcat
     2641 tgcctttagc cttggctttt ggggtatcaa gcggagctga tgcggccgca ggtttgatta
     2701 cggctatcat tgccggtatc gttattggcg gtttatcagg cggtttttat caaatatcag
     2761 gtccgacagg tgcgatggca gctatcttga tgtctattgc ggcaacaaag ggaatgcaag
     2821 gtgtattgct tgctactttt ttagcgggtc tatttttact tgcagcagga cttttccgat
     2881 taggaacact gacttctttt atcccagcac ccgtaattac ggggtttact tcaggtattg
     2941 ctatcattat tgcattaggt cagatcgata atttatttgg tgttcactcg gaaggtacaa
     3001 acgttattga aaaactaagt agttatcaaa cgataggatt tccgataaac acagcctctt
     3061 tgatcatggg agggctagtc attttaggga tgtttatcta tccaaaaaaa tgggcgaaac
     3121 gaatgcctag ttcgctgctg gctatcattt tggcaacagc agttatgcta ttgttccatt
     3181 taccagtagc aactgtgggt aagattccac aaacattgat cagtagtaat cgtttgaata
     3241 tgggagattt tagcttttct gccttgcaac aagtggcagt tccagctatt agcattgctt
     3301 tattaggaat gattgaaagc ttgctatgtg gtgcttcggc tggccgaatg gcaaataagc
     3361 ccttagatag caatcaagaa ttaatggcgc aaggaattgg aaatctgttg cttcctttct
     3421 ttggcgggat tcctgctact gcggccatcg cccgtacaag cgtggccatc aaatctggtg
     3481 cacaaactag attagctggt atgatacatg cagttgtctt actgctctcc atgcttgttt
     3541 ttgcgccagt gatgtcacag attccaatgc cagcacttgc aggtgttttg attgtgacgg
     3601 cttggcgtat gaatgaatgg gaaacgatca aggagctatt tactaataaa tattggtcag
     3661 cagttctatt gtttatcctt acgatgattt gtacagttat ctttgattta agtattgcta
     3721 tcgtgatcgg ggtgatcggc ggctgtgtat tttttgttgt caaaagcgct gctatcacga
     3781 tttcattaga aacgatcgat tggcaaagaa tggggctgcc agaaacggaa aagctgaata
     3841 actggacagt agtgtatatt agtggtccac tgttttttat gtcttcagaa aaactcaaaa
     3901 ataaattgga agaactaaat catcacgatg gtgtcatttt ctccatgcga ggcgtaccaa
     3961 gtattgattt gacggcacgt gcagtttttg atgaatttca agaaaaagca gagcaaagag
     4021 gacaaacgat tatctatact tccttgcagc cagaagtaga aaaacaactt tctcacttgt
     4081 gggaacatac attcacgcat caacatcaaa cagttgctca tgcgttgaca gctttacatg
     4141 cgaaatatac tgcaattagc cattaaaaca atgaaaaaga acagacaaga ctgtaaactg
     4201 aagattttat ggtcttgtct gttcttttta atattgctgt aaaagtgaag ctagtacttg
     4261 ccagtcttga tggataacag gtacaaggga gcgattgtag aaaatagctg ctggatgaaa
     4321 aagtggaaga attcgatagt ttttttctga ccattcgtag gcatcctttt gttctgttaa
     4381 ttgtaagaca ggccctgtat agagttgacc atgatttttg gtaaccgtat attctttgcc
     4441 aagtaaacgt tgaagaccaa tgtttccaag tgtcgcaatt aattttggct ggaccttcat
     4501 cagttcgtaa tccaatattg gtgcatgcgc aaatacttcg gaacgagtag gtgtccgatt
     4561 tggataaaca gtttctgact gttgtgtccg tttattgatc cgatgagtca cgcgatacgg
     4621 gcggctcctt acagcactgg tgatatacac ctcttctcgt gttaagccag ttgaagaaag
     4681 tgcctgcatc aattcttttc cagcttgacc gctaaaagga acatgcgtat caatctctgt
     4741 tttccctggg gcttctccca cgagcatcag tttaggatga agaggtcctt gcccagcgat
     4801 aaatccttct acaggacggc cgttcattct taaagaagct tcttgtatca gttcttttgg
     4861 gtattccatt tatgctcctc ctttttcttt tattataaga ataaaagaaa cacaatgcga
     4921 ctattttatt tggtagaact gtgaggatag aaaagcagaa gtattgcttg aatttttgtt
     4981 ttactttttg attttaaatt tagttgacta acggttgctg ttctggtaag ctagtactgt
     5041 tgtaattgtg gactccacag ctacaaccgc tcagaacaag taataagcac agcatatgct
     5101 gtcacttcgg atggcgagtc taagtatatc agaaggaggt gctttatagc atgtacgcaa
     5161 ttattaaaac tggtggtaaa caagtaaaag ttgaagtggg acaagcaatc tatgttgaaa
     5221 aacttgacgt tgaagcagga gaaaaagttg tttttgacga agttatctta gtaggcggag
     5281 aatctacaaa agtaggcgct ccaactgttg caggtgcaac tgttgaaggt actgttgaaa
     5341 aacacggcaa acaaaagaaa gtcgttactt tcaaatacaa acctaaaaaa cattcacacc
     5401 gtaaacaagg tcatcgtcaa ccatatacaa aagtggttat cgacgcgatc aacgcttaat
     5461 agcgtttgag aaagaaggcc tatatatgat caaaggaaca tttaagcgaa atgacgcagg
     5521 tcagatcgtt tcattcactt tgaccgggca tgctgatgct ggtccttatg gaagtgatat
     5581 cgtttgtgcg ggtgtttctg cgttagcgat cagcactgtc aacgggattg cctcattagc
     5641 cggttttgag ccgattgttg aaatgaatga agaagaaggc ggttatcttt ataccgaagt
     5701 cacttcagga atgacacaag aacaaaacaa tattgctgag attctattag aaaatctttt
     5761 attaggatta caatcgatag aagctgaaaa ctcagaatat atccaaatta aaacaattaa
     5821 tgataaatag gaggtgcaga ccatgttgtt atctatgaat ctacaattat ttgcccacaa
     5881 aaaaggtggc ggttctacat ctaacggccg tgactcagaa tcaaaacgtc taggtgctaa
     5941 acgtgctgat ggacaaacag ttacaggtgg atcaattctt taccgtcaac gcggtacaaa
     6001 aatctatcca ggtgtaaacg tgggtatcgg tggagacgac actttatttg caaaagttga
     6061 tggcgtagta cgtttcgaac gtaaaggccg taacaaaaaa caagtgtctg tttatccagt
     6121 agctcaagaa gcttaattga atcttatgat taaagaggtt gtgacaagac ttttgtcaca
     6181 gccttttttg tttataaaaa taaaagttgt agtggaggct acgaagttta ctttgtcttt
     6241 ttacacttaa tatttttttg ccaatttgga atcaggatgt tttgataact atcgttttca
     6301 attgatggaa gctatattgt ttgctatcag tgaaataatt atatggtaaa cagtgttctt
     6361 tttcttgttt ccattataaa aatcgtatcg ggatttttcg ttcttttaaa ttgaacattt
     6421 ctatctatcc gcgtgttatc aacaaaacaa aatcaggtaa atagttgacg aaacagaaat
     6481 aaatacatag tattatgttt tgaagcctaa gtacaatagt ctatagaaaa ggagcgatac
     6541 cattggcaaa acgcattgac cgaatttata tgtatgtcaa agaaaaaacc gctcatttaa
     6601 caaaggcaga atatgatcaa ggagtaacaa cacaggaaat tgctgaagtg ttagggattc
     6661 agcgaacaaa tagcagtaaa gatctgaatc agctagtgcg cgaaggaaaa ctgataaaga
     6721 cagacggacg accagtacgt tacatatatc aaacactcgt tacgcacgta aagccagtta
     6781 caaaacatgt agtcagttac aaagaaacgc cggtctctga agaaaaaaat acactccaaa
     6841 tagatactaa ggatatcttt gcaaaaatca ttggagctaa cggcagcatg aaaaattcag
     6901 tggaacaggc aaaagctgcg attttgtatc cgccaagagg attaaattgt ttgattacag
     6961 gacctaccgg atcaggaaag acttattttg cacacgcgat gtatcatttt gcaaaagcgc
     7021 atcatgtaat agatgaggaa acggaactga ttgttttcaa ttgtgctgat tatgccaata
     7081 accctgagct tttgatgagt catttatttg ggtacgcaaa aggtgctttt acaggcgcag
     7141 atgaagaaaa aatggggatt atcgatcaag cggatggcgg tatgctgttt ttggatgaga
     7201 ttcaccggtt gccgcctgaa ggtcaagaaa tgatctttta ctttatggat catggaactt
     7261 acagtcgtct tggggaaaca acgaaatccc atgaagcaaa tgtacggatc gtaggtgcga
     7321 ccacagaaga cccaggttct tctctattag aaacttttgt tcggcgtatc ccaatcaata
     7381 tcaaacttcc ggcttttgaa aaacgtcctg caaatgagaa agtcgattta gtaaaaatca
     7441 tgattgccca cgaagcaaac cgcacgcagc gaaagatttc tttgacagaa gatgtagcaa
     7501 aagcattgat cggcagtgtg acctatggaa atataggaca attgaagtca aatatccagt
     7561 tagtatgtgc acgaggattt ctaaatcata tgcaatcacc cgaaatctcg atcacaatcg
     7621 atgatttgac agaagggatt cgtagcggat tgattcaatt agcaagcaac cgcagtgcaa
     7681 tggcagagct ttctaaaata ttggagccaa agataactgt agcaccaaat gatacgatca
     7741 tgaaaatcca atcggactcc tatgagttac cttataatct atatgatatc atcggagata
     7801 aagcagcttt actgaagtcg gatggtttgg atcaagaagc aatcaatcat ttcatttcta
     7861 cagatatcaa catccatctg aagtctttct ataaagacca tggtttttct tttaatgcag
     7921 acagcaaatt agcagaattt gtagatccga aaatcataga agtgaccaat cagatttatg
     7981 taatggtcaa aagatcttta ccatatgagt ttcagcaaaa ctttatttat gctatgagct
     8041 tgcatatcag ttcttttttg aaaaaaatca acttaggaga agaacggcat acgaatgata
     8101 acatccgtga gatggctttt gattttccag atgaatatgc tgttgcgaaa gaagtgcgta
     8161 gttatatcga aacgtatttt caagtggaga ttccagaaag tgaagactat tacttgaccg
     8221 ttctactcgt ctcgttacgg gcaaatcaag caagcggcag aatcggtgta gtcgttgcag
     8281 ctcacggaaa cagcacagca agcagtatgg tccaagttgt ccaacagttg ttagatgcag
     8341 agaacgtacg agcagtagac atgcctttgg atatggatcc gaaaacagca ttggaccgaa
     8401 ttgaacgcaa tgtacaagaa gtagatgaag gaagcggggt catactctta gtagatatgg
     8461 ggtcccttgc gtcgtttaat tcgcaaattc aaagagacac tggaattcca gtacgtactg
     8521 ttgatatggt aacaacttct ctagttttgg aaactgtacg aaaggtctca gtattaggga
     8581 cagatctaga tatgttgcat gaatcattga aaaattttcg aggttacgca gaaatatctt
     8641 ctgtagaatc tgttcaggaa gcaaaaccta ttcataagaa aaaagctgtt ttggctatct
     8701 gcgcatctgg cgaaggtaca gcacaaagaa tcaaagaatt gatcgaacga gcggtaaaca
     8761 agcgtcaaga aacagaatta gaagttctag ctttgtcgat tgtggaagtg aaagaagaac
     8821 tgccagttat ccaaaaagaa tatcagatca tagctactac tgggattact gatttgaata
     8881 tccaagcccc atttattcct ttagaacgtt ttattgatca aaatatcgaa gtcattttgg
     8941 atcagttgct gatggaatca gaattggagg aaactgaatt catctcccta gatgaagagt
     9001 cagctaaaaa tacgtgtgtt gagtttatct ctgataactt catctttatt aatggtagta
     9061 agttaatcga tccaatgtgg caattttcta cacaaatctc tcagacgacg ggaatcggcg
     9121 atgaagaata tggattcaaa atcaacctag tgatgcacac agcaggaatg atcgaacgta
     9181 ttattcggaa tgaaccattg actgtggaag aaaacgaatt gacaaataca acgaatgatc
     9241 ctctttatag ccaattggca gcctcagttg ttctgttgga agatcagata aaagtaaaag
     9301 tgccgataga agaaatgtat tatctgctac gtctagtcca taatcagtta gataaaaaag
     9361 aatacactgt gccatgaata cacaaaaacg atacactttt atagtgtatc gtttttgtgt
     9421 attggttaag aatcctttaa attcaattag tgtatcgtaa aaaagttggc acgctttttg
     9481 cttatagtag tgtgtgctag gaggtggttg ttcacacaga aatgataggg gtttctgtga
     9541 agtagtgagg aagaaggagt tttgcagatg gatattcgat tggcacgtat agatgatcgt
     9601 ttaatccacg ggcaagtcgc aacagtttgg tcgaagcaaa caggtgttga acgtatcatt
     9661 gtgatcagcg atgtagtcgc tcaagataaa ttgagaaagt ttctactaaa agaagctgca
     9721 ccgccgggga tcacagcaaa tgtaataacc gtgcagaaaa tgattcaaat ctatcatagt
     9781 ggattattat cacgagcaaa agtgatgctt ttattcacca atccccaaga tgttgaagcg
     9841 gttgtccgct gcggtgtaca gttgaagtcg ttgaatatcg gcggtatgag ttttactgaa
     9901 ggcaaatcaa tgattaccaa ttttgtttca gtaaatcaac aagatattga ttcctttcgt
     9961 tacttgaaca gtcaagaagt ggagttagag attcgaaaag tacctgctga caggaaaatc
    10021 cttttgatgg aactactagc gaaaatcaaa aaggtgtagc aagaatggtt gttggaaaag
    10081 gtcaaataat tctgttgtaa tggttagcaa ttattaatat ttttgaattt gttacaacaa
    10141 aagtaaatag gaggtataaa tatggtaggg attatcctag caagtcatgg acaatttgct
    10201 gaaggaatct tacaatccgg ttcaatgatc tttggcgaac aagaaaacgt caaagccgtg
    10261 attttgaaac caagtgaagg tccagatgac ttgagagcca aattggaaga agcggttgct
    10321 tcttttgata atcaagacga agtgttattc ttagttgatt tatggggcgg aacaccgttc
    10381 aatcaatcaa acacattatt cgaagagcac aaagataaat gggcaatcgt cagcggtttg
    10441 aatttaccaa tgttgattga agcctacgca tcacgctttt caatggaatc tgctcatgaa
    10501 attgcagcac acatcattga aacagcaaaa gacggtgtaa aagtaaaacc ggaagaatta
    10561 gaaccggcag aagcaccgaa agcagcagtt gaagacgcac aacctaaagg agcacttcca
    10621 gaaggaactg tggtcggaga cggaaaaatc aaatatgtat tagcacgtgt tgactcacgt
    10681 ctgttacatg gacaagttgc gacagcttgg acaaaagcag tgcaaccaaa ccgtattatc
    10741 gttgtttcag atgcagtatc aaaggatgat ctgcgtaaga gactaatcga acaagctgct
    10801 cctccaggtg taaaagcaaa tgttattcct attagcaaaa tgatcgaagt agcaaaagac
    10861 cctcgttttg gaaataccaa agcattgctt ttatttgaaa atcctgaaga cgtattgaca
    10921 gctgttgaag gtggcgtaga catcaaagaa ttaaatgttg ggtcaatggc gcattcggtc
    10981 ggtaaagtcg ttgtaagtaa agtattgtct atgggacaag aagacgttga agcgtttgag
    11041 aagcttgaac aaaaaggtgt gaaattcgat gtacgtaaag tacctaatga ttcacgcgat
    11101 aacatggatg atattttgaa aaaagcaaaa gctgaattag caaaagcgta ataaataata
    11161 ttaaaattta taggaggctt atcatgtcta ttatttcaat aattttagtc gtattagttg
    11221 cctttctagc tggtatggaa ggtattcttg atgaatttca atttcatcaa ccactagtgg
    11281 catgtacatt gatcggttta gttaccggta acctcgaagc tggtatcgta cttggcggta
    11341 cgcttcagat gatcgcttta ggttgggcaa atatcggtgc cgctgtagca ccagatgctg
    11401 cattagcatc agtagcatca gcaattattt tagttttagg tggacaaggt gttaaaggtg
    11461 ttccttctgc gatcgcgatt gccgttcctt tggctgttgc agggttgttc ttaacaatga
    11521 tcgtacgtac aatcgctgtt ccaatcgttc atttgatgga tgcggctgct gaagaaggaa
    11581 acatccgtaa ggttgaaatg tggcacatca ttgctgtatg tttacaaggg gttcgtatcg
    11641 cggtcccagc agcagcgttg ctatttatcc cagcacaaac tgtgcaatca ttccttgaat
    11701 caatgccagc atggttaaca gatggtatgg ctatcggtgg gggaatggtc gtagctgtag
    11761 gttacgcttt ggtaatcaac atgatggcta caaaagaagt atggccattc ttcgttattg
    11821 gtttcgttgt agctgcaatt tctcaattaa cattgattgc tctaggtgct ttaggtgttg
    11881 cattagctct tatttacttg aacctttcta aaatgggtgg ttcatcaaat aatggaggcg
    11941 gaagcaactc tggtgaccct ttaggcgaca ttttgaatga ctattaatct tgaaggagga
    12001 aaataaaatg gcagaagaaa aaatcaaatt atcaaaaaaa gatcgtttag ctgttgcgtg
    12061 gcgctctacc ttcattcaag gttcatggaa ctacgaacgt atgcaaaacg gtggctgggc
    12121 attttctatg attccagcaa tcaaaaaatt atacaaaaca aaagaagaac gttctgcagc
    12181 attaaaacgt cacttggaat tctttaatac acacccatac attgcttctc caattttagg
    12241 ggttacattg gctctggaag aagaacgtgc gaatggcgcg cctgttgatg atgtagcgat
    12301 tcaaggggtt aaagtaggta tgatgggtcc tttagctggt gttggtgacc cagtgttctg
    12361 gtttacagta cgtccaatgc taggtgcact aggtgcttca ttagctatgg gaggaaatat
    12421 ccttggacca atcatcttct tcttaggttg gaacattatt cgttgggcat tcatgtggta
    12481 tacacaagaa tttggctaca aagctggttc taaaattact gatgaccttt ctggcggatt
    12541 gttacaagac gtaacaaaag gtgcttcaat tttagggatg ttcgtattag ctgcccttgt
    12601 acaaagatgg gtatcaatca aattcttacc agttgtatca actgtaaaat tagataaagg
    12661 tgcttacatc gaatgggata aattgccttc aggtggtgaa ggaatcaaga gtgcatttga
    12721 acaagttaat aatggcttag ccctttctcc tgaaaaggta acaacattac aagacaactt
    12781 agaccaattg attcctggtt tagctgcatt aggattaaca ttgttatgta tgtggttgct
    12841 taagaaaaag gtttctccaa tcgttatcat ccttggttta ttcgtagtcg gtgttgttgg
    12901 acacgtcatc ggacttttat aatccataaa aatatagctc gggcgttgtc ccgagctttt
    12961 tttatatagt atactgttca taaacaaata tctggaggga gaaaatggtt caatcaatca
    13021 atacaaaagt agacttggta attgatgcta cttcgtttac gggtctgaca gattacgggc
    13081 aaatcatgat aggtaataat ggttttgagt tttaccatgc gcgagataga cgcaaatata
    13141 tccaaattcc atgggaagaa gtggattatg tactagcatc agtcatgcta aagggaaaat
    13201 ggattcctcg atatgccatt caaacgaaaa aaaatggtac atacacattt tcttccaaag
    13261 aacctaaaaa agtgcttcgt gcgatcagag aatatgtaga tgaagataga atggtacaat
    13321 cattgagttt ctttgatgta gtgaaacgtg gtattcgtag tatgtttaaa cgcaagtaaa
    13381 aaataaagaa aacttctaag aggaggtttt ctttattttt ttactttgca gaagaaaata
    13441 tgaaatagca aaaccaatta tttgtcccct ttaaatccca tatgctaaaa ttgattagca
    13501 aagaaggagg ttatattatg agttggttat ggacattgat tgttggagcc gtgatcggag
    13561 caattgcagg tgcgatcacc agtaaaggaa attcgatggg ctgtgtaacg aatatcattg
    13621 ctggactagt cggttcaagt attggacaag cgattttcgg cgaatgggga ccaaaagctg
    13681 caggtatggc acttattcca tctattttag gcgcagtgat tttggtagca gttgtctcat
    13741 ttttctttgg aaaacgatca taagttttta caaaatagta aactaaaagg agttgcagcg
    13801 agactgtgac tcctttttgg ctttatttat ttaaaataaa aagaagtttt ccggaaattt
    13861 ttatttaact gtcgtgtacg aagaaaagtt tgctataatg gaaaaaagcg tgcaaagaaa
    13921 gagggagttt cattatgatg ctacgtgtag aaaaattgcg caaaaaaatg caagaagaaa
    13981 atttggattc atttttggtt accagtccgt acaatcttcg ttacttaacg aactttacag
    14041 gtacgacagg attagctgtt attactttgg aaaaagcatt ttttattact gattttcgtt
    14101 ataccgagca ggcggcagcg caggctcaag ggtttgaaat tattaaaaat gtcggaccta
    14161 tttttgatga ggtagcaaac ttagtacgca aagaagaact gcactcatta gcttttgagg
    14221 aaacaacagt ctcattttta gaatattcgg ttttagaaga aatcatcgat gcggaattag
    14281 tacctgtttc acagatgatc gaagaactca gagaagtgaa agatgaagaa gaaatcgcta
    14341 ttatcgaaaa agcatgtcat attgcggata tggcatatga tcacatcctg aaaatgatcc
    14401 aaccgggcat gactgagatt gaagtcgcaa atcaactaga cttttatatg cgttctcttg
    14461 gcgcttcagg tgtttctttt gatacgatcg ttgctagcgg attgcgttcg gctatgccgc
    14521 atggtgtagc aagcaaaaaa atcatcgaac aaggtgactt gatcacattg gactttggtt
    14581 gctattacga agggtacgtt tccgatatga cacgtacatt cgctattggt gatcctgggg
    14641 aaaaattaaa agaaatttat caaatagtct tagatgctca attagcagtt attgatgctg
    14701 caaaaccagg aatgactggt gtccaattag atgcagttgc tagagattat atttcaaaac
    14761 atggttacgg ggaagcattt ggacattcta caggacatgg gatcggttta gagatccacg
    14821 aaggaccaaa cgtttcttct cgtgcagaaa agcaatttgt accaggaaat gtgatcactg
    14881 atgaaccagg gatctactta ccaggaatcg gtggagtacg tattgaggat gacttgttga
    14941 tcacagaaga tggaaatcgt gtgttgactc gttcaccaaa agaattgatc atcttatagt
    15001 ttcatcaata gaagaagtaa gcgtaaaaat cagtgttcac agactttgtt atagaaaatc
    15061 actcgattta atgatacact atagaagaac ttttaagctg taagagataa taaagttggg
    15121 tgttttctcc aattcatagc agtttgcagc tgatcggcgg cagttttctt accacgtgat
    15181 cactatgccg catcatagag aattcggatg tatctcgtgc ttaggcaaag ggaggaataa
    15241 ataaatggca gatgaaaaaa atttgatttt aaacgcaaac caagatttag gagagatcgt
    15301 gatcgctcct gaagtcatcg aagtaattat cgggattgca gcttctaaag tagaaggcgt
    15361 atacggaatg cgcggaactt ttgccagcaa tgtcactgaa ttattaggac gtgcagctca
    15421 cggaaaaggt gtttacttag caaacgagga agatggcttg aaagtagatc tttactgtta
    15481 tctagaatat ggtgtttcag ttcctaaagt agcaatggaa atgcaggaac gggtcagcca
    15541 gcaagtcctt ttcatgacgg atatcgattt atctgaagtc aatatccatg tagtagctgt
    15601 tgttcctgaa aaattagaac aaccaacaat cgaagaactt tttgaagacg aagaggaaga
    15661 gaatgaataa agaattatca agacacgaga ttcgggaaat ggcattgcag gctttatttc
    15721 cattagactt caatgcagac ctaacaaaag aagatgcgat tttcaacgca atcgaattag
    15781 accaccgcga catgatcaac gaagatgaat cagagtttgt tcctgtttat cttgatacgc
    15841 tagttggcgg tgtctgtgca aaaaaagatg aattggataa agtgattgaa aaacatttaa
    15901 aaaacaattg gcacatcaat cggatctcaa aaatggattt ggtgatcttg cgtatcgcga
    15961 tttttgaaat gacttatgtg acagatgtac cagcggctgt tgctttaaat gaagcaatcg
    16021 agttggcaaa aacatttagt gatgaccgtt cacgtaaatt cgtcaacggt gttttatcca
    16081 atgtattgaa agaattagaa gctggggcgt aagtcctagc ttttttctat gaatcatcat
    16141 aaacctgtta taaatcggga aaattctatg gtagaatgaa aacacaaaaa atatctggga
    16201 gtggttagat ggcagaattg attaacggaa aagaattagc tgaaaaaatg caggcagaga
    16261 ttgctgaaaa aatccaaaaa ttgaaagata atggtatcca tcccggatta gtcgttttat
    16321 tggtagggga aaatccagcc agccaaatct atgtaagaaa taaagaacgt gtagcaaaag
    16381 aaatcggaat ccattcattg gtagagcgtt atcctgagac gatttctgaa gacgaactac
    16441 ttgcagaaat tgaaaaatac aatcaagatc ctagttttca tggtatattg gtccaattac
    16501 cattgccaaa gcatatagat gaagaaaaga tcctgttagc tatccgccct gaaaaagacg
    16561 tagacggttt tcatccgatg aatttaggca gactccttgc gggtaaaccg gacaagattc
    16621 cttgtactcc atacggcatc atgaaaatgt ttgaagctta ttctatcgat ccggcgggta
    16681 aacgagcagt agttatcgga cgaagcaata tcgtcggtaa accgatggct cagctactct
    16741 tgatggcaga tgcaactgtt actgttgctc attctaaaac cgaaaatctg gctgaactgg
    16801 cacaagaagc agatatttta gtcgtagcaa taggacgtgg acattttgtc acaaaagaat
    16861 tcgtaaaacc aggtgctgta gtgatagatg tagggatgaa tcgtgatgct aacggtaagc
    16921 tgatcggtga tgtgaaattt gatgaagtgg agcctattgc aggctggatc actcctgtgc
    16981 caaagggtgt agggccaatg actatcacga tgctgatgta tcaaaccgta aaatctgccg
    17041 aagcttttgg agcaggtgaa tagatggcac aagaatattt aactgtcact acattaacga
    17101 agtatttgaa aagaaaattt gatgccgatc cttatttaga acgcgtatat ttaacaggcg
    17161 aaatatcgaa tttccgttta cgtgccaatg cccatcaata tttcagctta aaagatgacc
    17221 atgcaaaaat atctgctatt atgttcaaag gagcattcca aaaattacga ttccagccaa
    17281 aagaaggaat gaaagtcctt gtcgttgggc gtatttcatt atatgaagcg ggaggttctt
    17341 atcaaatcta tgtagagcac atggagcctg atggaatagg tgctttatat caagaattgg
    17401 aagaacgaaa agaaaagctg atgaaggaag gcctttttca agggcctaaa aaaatgctgc
    17461 cacgtttccc aaagcgaatc gcggtcctta ccagtccaag cggagcggtt atccgcgata
    17521 tcatcacgac ggtgaaaaga agatatccaa ttgtccaatt ggttttgttc ccaacagttg
    17581 tacaaggaaa ccaagcagcg gacaatgttg tcaggaatat ccagagagta gaagagatgg
    17641 gcaatttcga tacaatgatc atcggtcgtg ggggtggttc gattgaggat ttatggccgt
    17701 ttaatgaaga gcgggttgct cgggcgattt atcaagctaa tacgccggtg atttcatctg
    17761 taggacatga aacagatacc acgatcgctg atttagtagc agatgttcgg gctgccactc
    17821 caacagcagc tgcagaatta gctgttcctg ttttgtcaga agagttgatg cgcattcaag
    17881 aacggcaagc tagattgcag caggcgtttg tacgccagat ccagcgcaaa caagaacggt
    17941 tcgagcgtgc tcgacgttcc tatgtatttc ggcagcctga aagattgtat gaaggtcaga
    18001 ccatcaaatt agaccagttg aaacagcgat tatatcaagc tacacagcaa atttatcatg
    18061 cgaaagaaaa acaaacgatc gcattaagcc accaattgga acaagtggct ccgctttatc
    18121 gagttaaagc agctcgccaa gaaactgctt atctagaaaa acgcttagaa gagaaaatcc
    18181 aacaatatat gaaacaacag cagcagcgtt ttgctcaagc tgttcaatct cttgatttgt
    18241 tgagtccatt gaaaatcatg ggaagaggct acagctatac gacgttaaat gatcaagtag
    18301 taaaaagtgt caccgagatt catcaagggg atttgctgac gatccattat caagatggaa
    18361 tcgttaaagg acaagtacaa gagatagaca aaggagaata aaaatatgga aaatccaact
    18421 tttgaagagt cactgcaaga attagaaaaa attgtcatgc agttagaaca aggagacgtt
    18481 ccattagaat cagctctaga ttcgtttaaa cgaggaatgg aattaagcaa acattgccaa
    18541 gatacattag ctaaagcaga agagaccttg acgaaaatga tgacagaatc aaatgaagaa
    18601 gttgattttg acggaaacga ggaaagctga gatgagatta actgactttt cagctattca
    18661 tctacctgct gtagaaaaag aaatcttgtc ttttttagat gagcatacaa cggatagagg
    18721 actctatgat gcgatgagtt attcagtgaa agcaggcggg aaaagaatac gtcccttatt
    18781 acttttaacg gccgttgctt cctttgatga gcctattgat gttcccgtct atcaagtagc
    18841 agctgcttta gaaatggtgc atacgtattc cttgatccac gatgatttgc ctgcgatgga
    18901 caatgatgat cttcgtagag gaaaacctac caatcataaa gtattcggcg aagcattagc
    18961 tatattggcc ggagatggtt tgcttacagg agcattccag ctaatcagta tggcacactt
    19021 aggtaattct cctaagcttc tgctgcttca gcaattagct gtttgtgcgg gatcacaagg
    19081 tatggttgct gggcaagctg cagatatcga gggcgaatcg aaaaagcttt ctttagaaga
    19141 attagcattt attcatgaaa gaaagacagg gcatttgatt cgttatgcct tgctggctgg
    19201 tggcatatta gcgaagcaac ctgaagaaat cttattgcta cttcaacgat tagccgaaca
    19261 tttaggttta gcttttcaga taagagatga tctactcgat gtgattggta caacgaaaac
    19321 attagggaaa acagctggta aagatgaacg tatggaaaaa aatacttacc cgcgtttatt
    19381 aggcctagaa aagacacgtg aggcgttgga gattgagctg ttatccgcca acaagatcat
    19441 agacaaatta gaagaggacg ttttttcttt tgatggcggg ctgatgcgcc agatgatcaa
    19501 gcaatttgat gtggagaaat gagggaaaga atggaaaaag aacgcgtaga tgtattagcg
    19561 gtcaaacaag gattatttga aacaagagaa caagccaaac gttcagtgat ggctggtttg
    19621 atttacaacg aaaaaaacga gcggtttgat aaaccgggag aaaaaattcc agtgagtagt
    19681 gaattaagag tcaaaggtaa aaaacttcct tatgtttctc gagggggatt aaaattagaa
    19741 aaagcactca aagcatttga tctatctgtt gaaggaaaaa cattgttaga tattggtgca
    19801 tccactggcg gatttactga tgcagctttg caaaatggcg caaaaatgag ttatgcttta
    19861 gacgttggct acaatcagct agcttggaaa ataagacaag atcctagagt cgtcgtaatg
    19921 gaaagagtga attttcgtta tgcaaaaccc gaagacttta ccttaggaat tccagaagtt
    19981 gctgttatcg atgtttcttt tatttcacta aaactgatgc tgcctccatt acatgctatt
    20041 ttaaaagaag agggagaagt gattgcttta atcaaacccc aattcgaagc aggcagagaa
    20101 gctgtaggga aaaacggaat tgttcgtgac cctcagaccc atcaaaaagt tttagaagac
    20161 attttgtcat ttgcggcaca aggtggatat gatgtgctgg aattaagtta ttctccgatc
    20221 acggggggag aaggaaatat cgagttcttg gctcacttga ggaaagtacc cgaaagcgga
    20281 acaatcaatt cagctattaa tatggcagaa gtggtttcaa atgcacacga acagtttgac
    20341 cataaataaa ttgtaactgt gaaaatcaag tgagaagtat gcggattctt ctttattata
    20401 ccaaggaaat aagctatcat tgattaagaa gaatatgcta aggagcgaag acgtaatgag
    20461 aaaaaaagat cggcatcgtt tgattactcg attgttgagt gagcaagata tccgaaagca
    20521 ggaagaattt gttgaaatcc tgaaaagcaa aggaatatct gttactcaag ctacgatttc
    20581 cagagatata aaggaactga aactgatcaa ggtaccggct tcagatggcg gctaccgtta
    20641 tagcatacca gctgaaacaa acgaagatgt aaatactaaa ttggaaaaac tattaaaaga
    20701 cgctttcgtg gcagttgacc aaatggaaaa atttgttatt ttgaaaacat tgccgggaaa
    20761 tgcttcggca gcagcaaatt tgattgataa acgttacaag aaagaattat tttcgattat
    20821 caatgatgac gataatgttt tgatgattac acgaactgaa gaccaggcag ttttattgaa
    20881 gaaagacttc ctgcattacc tttaagttga ggagcgaatg tgatgctaca agaaatcagt
    20941 attactaact ttgcgattat tccggaattg cggctttctt ttcacgaagg aatgaccgcg
    21001 ctgaccggag agactggtgc gggtaaatcc attattatcg atgctttagg tctgttagca
    21061 ggaggaagag gttcaagcga ttatatacgt caaggagcag aaaaatgtgt gcttgaaggg
    21121 ttgtttgaac taccaaaaca agaaggattc tctgaactga tggttgaatt agggatcgaa
    21181 acagatgagg acaatctgat tgttcgacgg gatatgtcct taactggaaa aaatgtttgt
    21241 cgagtgaatg gtcatattat cacattagct aatctgagaa gaatcggcag ttatttagta
    21301 gatatccaag gacaaaacga acatcaggaa ctgctccagc ctgaatcaca tcttgcttta
    21361 ttggatcgtt ttggagatgt agctttccaa cagaagaaaa agagttatca gcaagaatat
    21421 atctcttatc gtgagctgga aaaaagggta cgaaaagtgc agcaaaatga aaaatcctat
    21481 gttcagagaa tagatatgct ccatttccag caagaagaaa tagctgctgc tgatttgcaa
    21541 gtcggagaag aagagaaatt aaaagaagaa agagaaaaac ttagcaatta tcaaaaaatt
    21601 gctgatggat tagctgcagg ttacggagca ctgacgaata atgaacaaaa cagtgtagat
    21661 ggtgttggct tggccgtttc agaactgcaa gggatcgccc atctagatgt ggagtatgaa
    21721 gcaatttatg aaaatatcca aagtgcttac tatttgctgc aagatgcaat cggcgatatg
    21781 agtcgtcaga ttgatttatt ggagttagat gagagtcgtt tagaagaagt tacgcaacgt
    21841 ttagaattaa tccgacagtt gaaacgtaaa tacggcgaat ccattgagtc aatattggct
    21901 tactatgacg aaatcaccga agagctagct tcttctgatt tttcagaagg tcaattggac
    21961 aaaatgaaag aggaactaga gcaaaaagag cttctacttc agcaacaagc cgcagatctt
    22021 catgaagcgc gtaaaaaaat cgcaaaagaa ttggaaaaat ccattctgca tgaattgaaa
    22081 agtctgtata tggaaaacac tgagtttgag gtacgtttct taaaagaaga aaatagacaa
    22141 ttgaatcatg atggatttga ccaaatcgaa ttttacatta cgaccaatcc aggagagcca
    22201 ctgaagcctt tggtgaaagt cgcttctggt ggcgaactgt ctcggatgtt gcttgctttg
    22261 aaaactattt tttcttctga gcaaggtgtg acaagtatta tttttgatga agtggataca
    22321 ggtgtgagcg gaagagttgc acaggccatc gcagataaaa tttctcaaat atcgaaatac
    22381 tctcaagttt tgtgcatcac tcatctgcct caagttgctg cagtcgccga ctatcaatat
    22441 tatattgtga aagcagtgat tgatggacgt acgcaaactt ctgtttcaga gttgaaaaca
    22501 aaagaaagag aagaagaaat tgcacgtatg ctggctggaa gtgagattac aaaactcaca
    22561 ctcgaacatg caaaagaact attgaaactc gcaaaaagga cctgagccac ctcgcagtgg
    22621 ttcaggtcct tttcagcagc tgatagctat attttatttt tacatgacac tcattacagc
    22681 agtcaataca acagatccaa tcgttaaaat cagcattgtc caaatgacaa attttgttac
    22741 tttagcaaaa gtacttgttt gttttttttc acgcattgtt ttcaacctcg tcattaatta
    22801 gttgattcaa gtgtacaatc ttttttccat ttccacaaga gggctttttt ataaaaactt
    22861 cccttttttt aaataatagg tagttacgat acaaataaat aatgttaata gaactagcca
    22921 tataaaggca tcatcccttt cagcaatagg taacttaatg ttcattccat agatactgcc
    22981 gacgattgtc ggtatagtta aaataatcgt taaagaagtt aaaattttca taatattatt
    23041 cagattattc gatacgattg ctgaaaaagt ctgattcatt tgttctacta gttttaattg
    23101 aatgcgagaa gtagtcattg cctgctctgt ttccaccaat acatcacgta aatgattttt
    23161 caaagcatga ttttcttgga aaagtttatt ttgcgctagt tctttcaatg catctaaatt
    23221 agcagaagtc gcttctctga aataaacgag gcttttttgg atatccatga tttgataaag
    23281 ttgtttgttt tcagtggata cttgaagttt ggcttccaaa gtatcgcatt gagattgaag
    23341 cgtagctaaa taactgttgt aagagagtgt gacctgccaa atgaattgaa agaagatatt
    23401 gagattaggc gaaatatcac tttttggaaa ggtctggcta aagactttct ttaaaaacag
    23461 tggttcatga ttcgtaattg tgataagctt ctttttgggc gtcaaaataa tagagagcgg
    23521 gtatgtatcc acttgaaaat aaccgctagg acttgtttta gcaaaaggat attgtaacaa
    23581 taataacgct ggctttgtca actttgattg attgaattct tctgtacggg aattttctgc
    23641 atcgtccaat atggaagtga tgtaatctga cggaatttca aattgatgtg tcagctgatg
    23701 aatctcttct tgattaggac gttctacaca ataccagatc gtttggtcag tttcctttcc
    23761 ggtattacgc agtttctcat tatctaatgt aaaatatttg atcatgattt tcctcctgtt
    23821 gcctgtttct tttattataa cggataggga attggaatac atggaatgtg tttgtaagat
    23881 atagaatata actgcataaa tttaaataaa atgaaacagt tgtgtaaagt atatacagta
    23941 tacttgaagc aacgataaaa aaggagttta cgttcatggg cacattcaca ccacttatct
    24001 tgttttggta tatttacccg gtaatcgttt tgtttggttg ccaatttctt gtaaaattat
    24061 tttcgttaaa tcgtcgtttt aaaataaaag cccctgattt ggcgattcct tttttgtggg
    24121 gcggtatgca tgcattgtct agaaatacag ggacaatttc tatcttaccg tttttcttta
    24181 tttctgtttt gctaatggga atttgtattg ctgttttcca agcatattat tatgaagaaa
    24241 ttatttatcc gcgttatttc aagatgactt ggcgtttggt ttttctgttg acaatcgtct
    24301 tgtacgctgt cttgatcatt gtgaacatac tttcttacct atgaaaaaaa tagaaaagct
    24361 gtaaaaagtc ttttaaaagg ctttttgcag cttgattttt aaaaaaatgt ttatgaataa
    24421 aaaaagttgt tcccggattt cccagaaaag gtggtagaaa gtgggggatt gtggtagact
    24481 aattttagtt agtggaggaa tggggggctt tcaatgttga tgggtgaatt ccaacataat
    24541 attgatgcaa aaggacgttt aatcgtgccc tcaaaacttc gtgaagaact tggcgaaaag
    24601 tttgttctga cacgcggatt ggatggctgt cttttcggct atccgatgag cgaatgggaa
    24661 aatctggaag ctaaactgaa cgaaatgccg ttggctaaaa aagacgcacg tacttttgtg
    24721 cgattcttct attcggctgc cactgaatgc gaacttgata aacaaggacg aatcaatata
    24781 cccagcacgt taagaaatta tgcagctttg acaaaaggtt gcgtagtcat cggtgtatct
    24841 aaccgaattg aaatttggga tgagacacga tggcaagatt tttctgcagc agcagaagag
    24901 aactttgacg aaattgctga aagtatgatt gatttcggac tataagaata ggaagaggct
    24961 gactaatgac tgaaacattt caacactata cagtcatgtt gaaagaaacg gtagatggat
    25021 tgaacatcaa accggatggc gtttatgtag actgtacact cggcggtgcc ggacatagtg
    25081 aatatttatt aagccaacta agttctaaag ggcatctgta tgcgtttgac caagatcaaa
    25141 aagcaatcga tcacgccaag ctgcgtttag cttcttatgt cgaacaaggt atggtcacat
    25201 ttatcaaagc gaacttcaga gaattagaag aacgcttgag tgagcatgta gataaggtag
    25261 acggcatttt gtatgatcta ggggtttcct ctcctcagct agatgaagca gaacgtggat
    25321 ttagttatca tcaagatgca ccgttggata tgcgcatgga tcagtcagct cctttatccg
    25381 cttatcacgt aattaatgaa tattcctacc atgaattagt aaagattttc ttccgctatg
    25441 gcgaggagaa attttccaaa caaattgctc gtgaaatcga acgagtacga aaaacaaaac
    25501 caatccaaac aactggtgag cttgtcgaaa tcattaaaca agtcatccca gctcccgcaa
    25561 gaagaaaagg cgggcatcct gcaaaaagaa tttttcaagc tgtgcggatt gcagtaaatg
    25621 acgaactcgg tgccgaagag gcctctttag aacaggcaat ccggttattg aaagtcaatg
    25681 gaagaatcag cgtaatcaca ttccattcat tggaagacag aattgtcaaa agtatgttta
    25741 aagaatatag tacggtacaa gatctaccac cgggacttcc tgtcatacct gacgaattcc
    25801 aaccagaact gaaagtcatt actcgtaaac caatccttcc ttcagaggaa gagctaacag
    25861 aaaacaatcg atcacgcagt gcaaagttac gtattgcaga aaaaataaga atgaaagagg
    25921 agtagaatga tggcagaatt aaagaaaatg caagattacg aatatgattt acctgaattg
    25981 gtggatcagc cggaacaaca aatgcctgat tcttcttcga atcaagaaat cattcttcca
    26041 caatcaccgg caaaacgatt aaagcagatt tctgctttgg aaaaaattgc tgtggcaagc
    26101 gtggcgattg ctattgttgc tttatgtgtt ttaacagtta tgctgcgcac aaatatcagc
    26161 ggagctgaaa aagaaatcac gtcaatacaa acagaaatca atgataaaaa gcaagaaaaa
    26221 acgagtttag aacaagaaaa aaacgaactt tctcgtactg aacggattaa acaaatcgca
    26281 gaagaaaaag gattgtctat taatgacgac aatttaagga aagtgaagta aatgagtctt
    26341 aaaaataaaa ttcggcggtt tatggaaaag aaaaatctaa atccgatgaa caatcgcaaa
    26401 aaagtaggta tcattttatt tgctacgagt attggattgt tctttttatt tgccgtccgt
    26461 ttctcgtata tcgttattgg aggtcatgtt gctggtacct cattagctga aaaaacaaaa
    26521 cagttgtacc aaggaagtga agtagtaaaa gcaaaaagag gaacgattta tgatcgtaac
    26581 ggtgtggcgc tcgcagaaga tgcctcctct tattcaatta aagcgatact ctcaaaaaca
    26641 tatacctctg gggataaaaa actgtatgtt gaagaaaaga attttgataa aatagcagaa
    26701 atcctgcata agaatctttc tatagacaaa aaagatgcac tgaatatttt agaggacggc
    26761 gcaaaaaaag agctgtatca agttgaattt ggtagctatg ggaaaaatat ctcccaagaa
    26821 accaagcaaa acatcgaagc ggacatgaaa aaagaaggtg tcgctggtct ttattttgtc
    26881 gaccatcagg ctcggatgta tccaaatggc gtcttttctt ctcattttat tggatacgca
    26941 gttccagaca aagatgagaa tggcttagtt ggtaaactag gtttggagtc tgcttacaat
    27001 gatatcttga gcggtaaaga tggtaagatt atttatcaaa aagataattt tcaaaatcct
    27061 ctgccaggta cagtggcaga agaagaaaaa gctgtcgacg gacaagatat ctacacgact
    27121 ttagacagca gactacaaag ttatttagaa acactgatgg atcaagtaaa tgaagaatat
    27181 cagccagaag aattgacagc agtcctgatg aaagcaaaaa ccggagaaat cttggcaatg
    27241 ggacaacgac ctactttcaa tcctgaaaca atggaaggat tgactggaaa agatgctatc
    27301 tggcgtaatt tcttggtaca agatagttat gaaccaggat caaccatgaa agttttcact
    27361 actgcagctg ctatcgaaga aggagaattc aacgagaatg aaaccttcca atctggaaaa
    27421 atccaagtag aagatgctac gatcaatgac catgactttg gtgaaaaagg tgtgctgacc
    27481 atgcgtcaag ctctttcatg gtcaagtaac gtcgggatgg tcatactgga acagcgatta
    27541 ggcggacgat ggtataacta tttacaaaaa ctgggatttg gacaaagtac tcattctgga
    27601 ttagatgatg aagtaaacgg tgctttacct acattaaata ttgtcgaccg agcaatgagt
    27661 gcttatggac aagcggtagg tgtgacgaat ttccaaatga tgaaagcttt cacttctatt
    27721 gcgaataacg gtacaatgat tcaacctcga tatatcagca aagtggtgga tccccaaact
    27781 ggagaagagc gaacaactca aacagaagtt ctagggcaac ctttttcaaa agaaacaaca
    27841 gaaaaagtcc gtgaatatat gagagatgtt gtcgaaagcg aaaactacgg tagtgcttat
    27901 ggtgtatata gtgtacctgg atacaatgta tcggcaaaaa acggaacagc ccaaatcgct
    27961 tctgatacag ggggatatca aacaggagat acagcctacc tgtattcgat tgtggagatg
    28021 gttccttctg aagatccaga ctatgtcttg tatctaacaa tgaaacaccc taagacatat
    28081 gatcgaatgg cattggctaa aatcgcaaat ccattgatga aacgggcaat ggattttaaa
    28141 gaaactgaag aagattcaga tacagaaaca aaaacagaaa aagtatccgt agccgattat
    28201 cgtaatcttg aagcggacgt tgcagcagct gatgctcaaa aaagtggact gcaacctgta
    28261 gtgatcggta atggtaaaaa agtacaaaaa caatctactg ccaacggtga tcagttgatc
    28321 tctggagaaa aactgatcct atatactggt ggtgataagc tgatgcctga cgtaacagga
    28381 tggtcaaaag cagatatcat gaagctgggg aaaatcctcg gtattgaagt tagttttgat
    28441 ggagatggtt attgtgtcaa acaagaactt gctccatatg aaaaaatcac tgaagacaaa
    28501 cttagtttta ctttagaaga ataagaagag aaataggaga gaaaagagca tggaatggac
    28561 acaagcattg attcccattg tcagcagttg tgcaatgaca attgccgcaa tgccgctatt
    28621 tattggttat tttcaaatga aaaagcaagg tcaggcgatt cgtgaggagg gaccaaagtg
    28681 gcacaatagc aaagccggaa ctcctacaat gggcggctta gtgtttctga tcggctctat
    28741 tttgacagga atttgggttg gagcttggca aaaacagcta actcctactc ttttcatctt
    28801 gctttttgta ttagcgttat acggagtaat cggctttctt gatgatttta taaaaatatt
    28861 caagaaaaga aacatgggac tgaactcgaa gcagaaattg attggacaga ttctaggggg
    28921 aatcatcttt tatcttgttt accgttctga aggttatcca ggtgtattga atttcttcgg
    28981 actagatcta cctttaggaa tcatttatgg tattttcgct ctcttctggc ttgttggatt
    29041 ttcaaatgca gtaaatctga cagatggcat cgatggatta gttgctggct taggaagtat
    29101 ctcttttgca gcttacggtc taattgcttg gcatcagcat cagtatgatg tattaatcat
    29161 ttgcttaagt gttttaggag gtttactggg tttcttcgtc tacaacagaa aacctgccaa
    29221 gatttttatg ggagatgtcg gttcattagc gttgggcgga cttttagcgg caatttctat
    29281 aatgctaaac caagaatgga cattgctttt gattggtttg atctatgtta tggaaacagc
    29341 aagtgtgatg cttcaagtta cttcctttaa gcttacagga aaacgaattt ttaaaatgtc
    29401 tccaattcat catcactttg aaatgtgcgg atggtcggag tggaagattg atacagtttt
    29461 ttggttgatc agcattgtga cttcgttgat cacattatgg atcgtttggt aggagatgac
    29521 gggaaatgaa aaaaatatca acatatgaaa ataagaaagt gcttgtctta ggactcgcaa
    29581 aaagcggagt aagtgcggcc aaattattac atgaattggg cgcacttgtc accgttaatg
    29641 atggaaaacc ttttgacgaa aatccggaag cacaagagct gctttcttta gggataaaag
    29701 taataacagg tagtcatcca atcgaattgt tggatgaaga attttcattg atggtcaaaa
    29761 atccagggat tccctacagt catcctttag tagcaaaagc ccaagaaatg ggtattccgg
    29821 taattacgga agttgagcta gcttacgaag tagcggaatg cccaattatt gggattacag
    29881 gaacgaacgg aaaaacaacg acaacaacga tgacaggact actactgaat gcaggagcag
    29941 atcaaggaat tgcacgttta gcgggtaata ttgggtatcc agcaagtggt gtagcgcaag
    30001 aagcaaaatc agaagataaa attgtgatgg aattgtctag cttccaactc atgggaatca
    30061 cagatttccg ccctcatata gcggtgatta ccaatatcta tgaagcacat attgattatc
    30121 atggtacaag aaaagaatat gtcaaagcta aatggaacct tcaaaaaaac atgacagaaa
    30181 aagattatct gatccttaac tggaatcagt cagaactaca agaattagcg caaagaacaa
    30241 aagcacgcgt actgcctttc tcgacaaaag aagtgttgga agacggtgtg tatgctgacg
    30301 attactcaat atactataaa aaagaaaaaa taatggaaat atctgaactt ggcgtaccag
    30361 gtaagcataa tgtagaaaat gcactagctg ctatttctgt agcaaaattg tatggtatat
    30421 caaatgaagc tatacgagaa acgttgcatt ttttccatgg cgtaccacat cgtacgcaat
    30481 atgtaggaga aatccaaggc agaaaatttt ataatgattc aaaagcaacc aatattttag
    30541 cgactaaaat ggctctaagt ggatttgaaa cgtctaaggt cgtgttattg gctggcggat
    30601 tagacagagg aaatacattt gatgaattaa ttccttcatt aaaaggaatc aaagcaatgg
    30661 tcgtatttgg ccaaacaaaa gaaaagttga tggatgctgg aaaaaaagca ggcatcgaga
    30721 caatagtaac agccgattct gtagaacaag cagttccttt agcattagaa aacagtacag
    30781 atggtgatgt agttttatta tcaccagcga atgccagctg ggatcaatac ccaaattttg
    30841 aaactagagg aaacagattc atggaagctg tgaaccgatt aaaatagaaa aagtagaagc
    30901 gagcgataaa aaatgaaaat tttggttaca ggcggaggaa cagggggaca tatttatcca
    30961 gctcttgcct ttgtcaatta tgtaaagact caagaaccga atgctgaatt catgtatgtg
    31021 ggagcaaaac gaggtctaga aaacaaaatc gtccctgata caggaatgcc tttccatacc
    31081 ttggagattc aaggatttaa acgaaaaatt tccatgcata acatcaagac ggtccgattg
    31141 tttcttaaga gtatccgtca agcaaaaaaa atcctcagtg attttcaacc agatatcgtt
    31201 atcggtactg gaggatatgt ttccggagcg gtagtgtacg ctgcagccaa aatgggtatt
    31261 ccaacagtta tccatgaaca aaacagtgta ccaggtgtta ccaataaatt tttaagccga
    31321 tatgtggatc ggatcgctct ttcatttaaa gatgcggctt ccttttttcc tgaaaacaaa
    31381 gcagttcttg taggtaatcc tcgagcacaa gaagtagcag atactaaaaa atcagatatt
    31441 ttgaaaacat ttgatttgga tccagaaaag aaaacagtct tgatttttgg cggtagtcaa
    31501 ggagcactta aaatcaatca agcagtatca gtttttttaa gtgaatatat tccttcttct
    31561 taccaagttt tgtatgcttc aggagataga tattatgaag agatcctaaa taaaataaat
    31621 cctgaaatac aaaatattag tgtccagcct tatatcaaaa atatggcaga ggtcatggct
    31681 tccagtgatc tgctggtggg gcgtgctggt gcaacttcga tcgcagaatt cacagctctg
    31741 gggttaccgg cagtgttggt tcccagccca tatgttacga atgatcatca gactaaaaat
    31801 gcaatgagtc ttgttcacgc aggagcagca aaaatgattg cagataatga actaacaggt
    31861 gaatcactaa gtcagacagt caacgaaatc atgggtgatg aagaattgca aaagcaaatg
    31921 tgccgagctt ctaaagaaca aggaatccct gatgcttcaa aacgtcttta tgacttagta
    31981 aaacaaataa tcaaaaaata aaggcggtgg tcttagtgag taagaaaaaa gaaccaaaaa
    32041 aattgtctca tccgtcttct gatgaaaaca atttgactcc ttggcaaaag gctaaccgaa
    32101 aatatctggc agaacaagag atgaaaaacc aagagccaaa aaaagaagac ataacattag
    32161 atacacccct ttcagattct gaagaagaaa aaacggttca agaggaacag caagaagaaa
    32221 gccagtccga gaaaaaaatc gaattttttg aagagatcaa gcaaaagaaa aacggtggac
    32281 catataacgg ttcttttttg aaccggctgc ccaatttaaa aagtcaacgg cacaaagtac
    32341 tatttcgtcg gttagctttg atcatcactg tattgggtat accgctgatt tttttgatct
    32401 attatgtttc tccttatagc aaattacaag cagttgcagt atcaggcaat aagacagtca
    32461 acagccaaga aatcatctct gatacaaaat tgtcattagg agaaaatgtt tggggacagt
    32521 attttcatcg atctacttat atcgatcgcc ttaaaaaagc acagccaaga atcgaaacag
    32581 caaatataca tttcaaaggg atgaatgaat tcgatttgga tgtaacagaa tataaagaga
    32641 ttgctttgat cgcaaaaaac aatcaatact acccagtgat tgaaaatgga acagtattag
    32701 atgaaaaagt agcaaatcct acaaaaaatc tccctatctt ggaagagttc aaagactctg
    32761 caaaaatcaa agaattaaca aagcaataca atcagttatc atcagaatta caaaaagcaa
    32821 tttctgaaat caagtacacg ccaagagcaa gcaataaaaa tctgatccaa ttgaatatga
    32881 atgacggcaa tcaagttatt gtaaatatca ataatcttgc gaaccaaatg aaatattatt
    32941 cgcaagtagc caaagatatg gatgaaaaag gtgtgatcga catggaagtt ggtatcttct
    33001 cgcatcctta cggtagcact caagaaacgg aagaatcggg ccaatcggaa gaaacaactg
    33061 aaagtgaaga aaatgcggat caaacaaacg aatcaagtga agaggcagaa acgcaaaaag
    33121 cacaaacacc tggatcgtct agcacaaacg gatcatctga ttcaaatgat tcaagtgaaa
    33181 caagtcaaat agaagataat ccaagtacaa ctccgtcaag tttaaatgaa aattgataaa
    33241 acaactttaa aaagtaagaa tgtactttct aaaaaccagt aatttatggt agaattggaa
    33301 gcagtgaata tatctattaa taagtatatt ttaaaacgga cgctagttgt tcgcttgtat
    33361 atggaatagt aagtaggagg gaatcccatt catggcaaaa acaggaatgt atgtaggcct
    33421 tgatattgga acgacatctg ttaaagttgt cgtggctgaa tatatcgaca gccaaatgaa
    33481 tattattgga gtaggaaacg caaaatcaga agggattaac cgaggcatta tcgttgatat
    33541 cgataaaacg gtccaagcga tacaacgagc agtacgacaa gcagaagaaa aagcaggtat
    33601 ccagatcaaa ggcgtaagtg tcggtttgcc agcaaacatg cttgaagtag aaaattgcca
    33661 gggaatgatt gcagttaacg gagattcaaa ggaaatcacc gatgaagatg tcagaaatgt
    33721 ggcttcagct gcccttgttc gttcaatacc tcctgaacgt caaatcgtgt caatattgcc
    33781 acaagatttt actgtcgatg ggttcgaggg aatcaaagat cctcgtggaa tgatcggcgt
    33841 aagattagaa atgtacggtc tgttgtttac aggacctaaa acgatcatcc ataacatacg
    33901 taaatgcgtg gaaaatgccg gattaatcgt caacgaaatg gtgattactc ctttagcgct
    33961 gactgaatca attctttctg acggagaaaa agattttggt acgatcgtca ttgatatggg
    34021 tggcggccaa acaacaacgg ctgttatgca tgataagcaa ttgaagttta ccaatcttga
    34081 ccaagaaggt ggcgaatttg tcactaaaga tatctctatt gtattaaata cgtcatttaa
    34141 caatgcagaa gcgttgaaaa taaactacgg ggatgcatac ccagaacgga catcaccaga
    34201 tgaagaattt ccagtagatg tgattggtca gtcagaacca gtgaaagtcg atgaacgcta
    34261 cttgtcagaa attatttcag ctcgaatgga acagattttc aacaaagcaa aagatgcatt
    34321 ggaccaaatc gaagcattag agttgccagg tggcgtcgta ttgacaggcg gagctgctag
    34381 tcttcctggt gttgtggact tggcacaaga aatcttcggc gtaaatgtaa aattgtatgt
    34441 tccaaatcac atggggctga gaaacccggt atttacaaat gtaataagta tcgtggatta
    34501 ttcagcaaac ttgagtgaag tgtatcaatt ggcaaaaatt gctgttacgg gtgaaacctc
    34561 agcagctcgt caaatggtag ttgaacaaga aacaacaaac acatatgaga gctatgaagc
    34621 acctgaagaa acaatctacg atgagccgga accaaaagag tccggagaaa atgtaaaaaa
    34681 taaaatcaag ggtttcttta caaatatttt tgattaattc atcctgggag gaataagata
    34741 tggaattctc aattgataat aatatcaatg acggcgcagt aatcaaagtc atcggagtcg
    34801 gtggtggcgg tggaaatgct gtaaaccgaa tgattgaaga aaacgttaaa ggtgttgaat
    34861 tcattacagc caacacagac gtgcaagcat taaaaaattc aaaagctgaa acagttatcc
    34921 aattaggccc caaatatact cgtggtttag gtgctggttc tcagccagaa gttggacaaa
    34981 aagcggcaga agaaagtgaa caatccttac gcgaagcttt agacggtgca gatatgattt
    35041 tcatcactgc aggaatgggt ggaggaaccg gtacaggtgc tgcaccaatc gttgcaggta
    35101 tcgcgaaaga attgggcgca ttgactgttg gtgtcgtgac acgtccattc acttttgaag
    35161 gaccgaaacg tggccgtttt gctgcagaag gtatcgctcg tttgaaagaa aatgtggata
    35221 cattattaat tatctcaaat aaccgtttat tagaagttgt agataaaaag acaccgatgc
    35281 ttgaagcttt ccgtgaagca gataatgttt tacgacaagg tgtacaaggt atctctgatt
    35341 tgatcacagc gccaggttac gttaaccttg actttgctga cgtgaaaaca gtgatggaaa
    35401 accaaggtac agcattgatg gggatcggtg tggctagtgg agaagatcgc gtagtagaag
    35461 caacgaaaaa agcaatctcc tctccattgc ttgaaacatc tattgatgga gctgaacaag
    35521 tacttcttaa catcacaggc ggtttggata tgacattgtt cgaagcacaa gatgcttcag
    35581 atatcgtagc aaatgcagca actggcgatg taaatatcat tctaggtaca tctatcaatg
    35641 aagaaatggg cgatgaaatc cgtgtgacgg tcatcgcaac aggtatcgat gaatcaaaaa
    35701 aggaacgcaa gtctagccga ccagctagac aagcacaaat gcaatcacct gctcaaaaga
    35761 ctgtattaga tatggatcaa gctaaaccaa cttcttcaga agaagaaaac agttttggcg
    35821 attgggatat cagacgtgaa caaaatgttc gtcctagagt tgatgattcc aattttgaca
    35881 atatcgaaaa aaaagaattt gatacattca accgcgaaga aacaaaatct catggcgatg
    35941 atgaattaaa tacgccaccg tttttccgtc gtaaaaaata aaggagagga agagcacatg
    36001 attgctgaca acttgcagaa aatcaagcaa gaaattcagg attcgtgtgc tcttgttcat
    36061 cgtgatccga aagaagttac attagtagct gtaacaaaat ctgttgaatc cgctcaagct
    36121 gaagaattgg ttagagctgg cgttatgaat tgtgcagaaa accgagtaga taaattatta
    36181 gaaaagaaac aagatttatt tgattttcct gaaataaagt ggcatttaat tggtaattta
    36241 cagcgcagaa aggtaaaatt gattgtaaat gaaattgatt actttcatgc gttggacagt
    36301 ttaagattag cagaagaaat ccagaagcgg ttagagaaag aattatcctg ttttattgaa
    36361 gtaaatgttt ctggtgagga atcaaaacat ggaatttcac cagatgagct tttaccgttt
    36421 gtggaatctt tagctgcctg cacaaaaatc aaggttgttg ggttgatgac tatggcgcct
    36481 aaagaagctt ctgatgagca aatccataaa gtgtttggta cgctgaaaga attgcgtgat
    36541 cttgttcaag caaaaggtta tgcccatgca ccatgtagtg aattaagtat ggggatgagt
    36601 caagactttc aaattgcgat tgaagaaggt gcaacattta tccgtgtagg aacagcgcta
    36661 ttcaaagacg aataaaggag gaacaaaaat gccgctttta aacagaggag caattgctaa
    36721 ttttttcgga ttagctgatg aggaagagta cgaataccaa gattatcctg aaacaacaaa
    36781 aaaggctgta cagccaacta aaaaaaatac aacacagaat caatcaactc attctgtatc
    36841 tgctgcgaat actcatgaaa aacaaaaaac ggcgacttca cgtcctgtaa cgcatgaaag
    36901 tattcagccg gctgaaaaga aaaaagtaat tgaactacat caatcaccta caaaaactgt
    36961 agcgaaagaa agaacagctt caagaacctc tacacaacct aaagcaaatc ttgctggaaa
    37021 aatcactgta atggaaccaa gagcttattc tgaagctatg gcgattgcta aacgaatcat
    37081 tgctggagaa gcaaccttag tgaattttca tttagtagaa gaaaaacaag cgagaagaat
    37141 cgttgatttt ctaacaggaa cagtttatgc actagatgga gatatcaaac gtgttggaga
    37201 tgagattttt ctttgtacac cgactgggat ggagattgac agttcaaccg ctcaatcttt
    37261 tgcagatgcg aatttgtttg atctgtaaga ggaggaacta cgatttatac tattgcacta
    37321 ttacttcatt tacttcaacg ggcagcctat ttctatagca ttatcttgat ggtatatgca
    37381 ttgctctctt ggtttccagg cgggtatcaa tcagggctag gacgattatt agctaagatc
    37441 tgcgaaccgt atatcagttt gttcgatcgt ctgcctttga ggattggacc cttggatttc
    37501 acaattttag gggcaatcct gatcttgaac ttagccgtac aaggtttagc acagatcgtt
    37561 atatggataa ctgtccattt agtttattga ttgaagcaac aaaatcttta ttctcagaat
    37621 agataggagg ggaaaatttt ggatgcaaat gtataccagc actttcgggc agatgaacgt
    37681 acatttatcg attcggtagg cgattggatt gaacaggttc aaggacaata tgcaccctat
    37741 ctgaccgaat ttcttgaccc aagacaatcc tatattttag aaacactgat tcgacaaagc
    37801 agtgatttgc gtttcatgtt ttatggcgga tatgaacagg cagaaagaaa aagatgtttg
    37861 attttccccg attattacga acctgtagag gaagattttg aaacagcatt gtatgaaatc
    37921 cattatccta gcaaatttgc cagcctaagt catgggaaaa tccttggaac tttagtggga
    37981 acggggatca aacgctctta ctttggcgat atcatctcgg acggtgatcg ctggcaagta
    38041 tttattgcaa atgaggtgga tcattttgtt gctgcacaag taacaaagat tggaaaggtt
    38101 gctgtacgct tggaaccaat caaatacaca gaaatgatta tgccgaaaga tagctggaca
    38161 caagaaagag gaacagttag ttccatgcga ctagacagtg tgatctctga gatttataat
    38221 atttccagac agcggtccaa gcagctgatc gaagctggta aagtaaaagt gaactggaca
    38281 gaaaatacaa gacctgattt tgtacttgaa ctattagata ttatttcagt cagaggttat
    38341 ggcagagtcc agatccaaga acttgagggg aagacgaaaa aagaaaagta cagggtactg
    38401 ttcggtgtat tacgtaaata aaataaaaag gtggtttact catggcttta actccattag
    38461 atatccaaaa taagacattc ccgacaaaaa tgcggggata taatcaagac gaagtagatg
    38521 atttcttaga tttagttgtt cgtgactatg aggaattgac tcaaagaaat cgagaattag
    38581 aaaaagcagt caaacattct gaagaaaaac ttgagtactt caatgaatta aaagatgctt
    38641 tgaaccaatc aatcatcgta gctcaagata cggctgataa agtaaaaaca agtgcaagca
    38701 aggaatccga agtgatcgtt acttctgcac aaaacaaagc agatgagtta gttgcgaacg
    38761 ctgaaaaacg tgcacatcaa ttaacaactg atgcagaaga aaaagcaaga aaaatcttga
    38821 cagatgcaac agaaaaagca agacagcttg cgacagaaac tgaagatctt aagaaaaaaa
    38881 cacgagtatt ccatcaacgt atcagcttga tgcttgagtc tcaattagaa caagtgaaaa
    38941 gtccggaatg ggatgaaatt ttacaaccat tctccagcta cgtgactgac agccatgaag
    39001 tgatcaaaga agttttagca aaacagcttg acaatgaaaa tgatactgat gtaaactcag
    39061 acacaggagt catagaagca cctatgacgg catttgatac acaggctatt gatatctcga
    39121 tcgtgcctgg tgaaaatgaa aacgagtaga acagaaaagc actttgttat tcttaaagcg
    39181 agccgatgag agtggaagtt cggtaagaca ctgcatggtg aaagatcctc tacttgagac
    39241 ctgcttttcc gaaattagag taagaagcag cggctgacct cgttattggt cacagagagt
    39301 ttgcactaga tagatgcaac taaatttggg tggtaccacg gcatgttcgt cccttgcggc
    39361 tgaacatgct tttttgtgtc cggaaaacaa ataaaggagt gtatggttga atgaaaatga
    39421 aagaaacctt gcaattagga aaaacaaaat tccctatgcg tggtaatttg ccaaaccgag
    39481 aaggcgagtg gcaaaaagaa tgggaagaaa atcgaatcta ccaaaaaaga caagagttga
    39541 acgaaggaaa acctagcttt gttcttcatg atggacctcc atatgccaat ggtaatatcc
    39601 atttaggaca ttcattgaat aaaatcagta aagacattat cattcgttca aaatcaatgt
    39661 ctggctatcg tgcaccatat gttccaggat gggatacaca tggattgccg attgaacaag
    39721 tattggctaa taaaggcgtg aaacgtaaag aaatgtccat ggcagaatac ttggaaaaat
    39781 gtcgtgaata tgcactttcc caagtagata agcaacgagc agatttcaaa cgcctaggag
    39841 ttgcaggaga ttgggaacat ccttatgtta cattagatcc ttcttatgaa gctgcacaag
    39901 tacgcgtatt tggtaaaatg gctgaaaaag gctatattta caaaggattg aaaccaattt
    39961 actggtctcc gtcaagtgag tcttctttag cggaagctga aattgaatat aaagatgtaa
    40021 aatctccatc tatttttgta gctttcaatg tcaaagacgg caaagatatt cttgatgaag
    40081 atacagcttt tgtcatttgg acgacaacac catggacatt gccagcaaac caaggtattg
    40141 ctgtaaatcc aaaatttacg tatgtattgg tggaagccga tggccgtaag tttgtcgtag
    40201 cgaaagattt gctagaaaca gtccaatcag aaatcggttg ggaaaatgta acagttctaa
    40261 aagaatttgc tggacaagaa atggaatata tgactgcaag tcatccattc tatgaacgtg
    40321 aatcacttgt gattttaggc gatcatgtta ctttagacgc tggtactgga ttagtccata
    40381 ctgctccagg acatggggaa gatgactata tcgctggtag caaatataaa ctatctgtag
    40441 tgtcacctgt agactcaaaa ggattgttta cagaagaagc acctggattt gaaggtatct
    40501 tttatgacaa agcaaatcct atgatcactg atctattaaa agaaaaagga gctttgctga
    40561 agctagattt ctttactcat agttatcctc acgattggcg gacgaaaaag cctgtgatct
    40621 atcgggcaac tccacaatgg tttgcatcta tcgataaatt ccgtcagaat attttggatg
    40681 aagtagaaaa agtagagtgg gttatcccat ggggtaaaac acgtttgtat aatatgatcc
    40741 gtgaccgcgg cgattgggta atttcccgtc agcgtgcatg gggagtacca cttccgattt
    40801 tctatgctga aaatggagaa gcaatcatca caccagaaac aatcgaacat gtggcaaaat
    40861 tatttgctga acatggatca attatctggt ttgaaaaaga agcgaaagaa cttcttcctg
    40921 aaggatttac ccacccaggt tctcctaatg gcgaatttac aaaagaaaaa gatatcatgg
    40981 atgtctggtt tgattctggt tcttctcatg aagctgtttt acgtcagcga ccagaattat
    41041 cattcccagc agatatgtat ttagaaggat cagaccaata tcgtggctgg ttcaactcaa
    41101 gtatcacgac tagtgtggct atcaatggtg tagcaccata caaatcagtt atttctcaag
    41161 gatttgcttt agatggtgaa ggccgtaaga tgagtaaatc tttaggaaac atcattgcac
    41221 cagaaaaagt gatcaaacaa tttggtgcag atatccttcg cttatgggta tctagtgtag
    41281 attatgaagc agatgttcgt gtttctatgg atatcttaag tcaagtggca gaagtatatc
    41341 gtaaaatcag aaatacgatg cgtttcttat tagcgaatac agaagatttc gatcctaaaa
    41401 aagatactgt ttcgtacaat gatttacgtt ctgtagacaa atatatgacc gttcgattga
    41461 accaagtaat caaagaaatc cgagaagaag ggtacgacaa atataacttc atgcatattt
    41521 accgtacagt tatgaacttc ttgacggttg atctatcgtc attctacctg gattttgcta
    41581 aagatgtagt ttatattgaa gcagaagatg attatcaacg tcgttgcatg caaactgttt
    41641 tctatcaaac agctgtagct ttgacaaaat tattgactcc tatcattccg catacagcag
    41701 aagaaatctg gtcattcctg aaagaagaag aggagtacgt tcagttaagc gagtttcctg
    41761 gttatgaaga gtttgcaaac caagaagaat tgatggatac ctggactgct ttcatggact
    41821 tccgtgataa tgtcttaaaa gcattggaag aagcaagaaa cagcaaattg attggtaaat
    41881 ctttggaagc aaaactaact gtttatccaa aacaacaagt tcgtgaaatg ttaaaagctt
    41941 tggatgcaga tattgcacaa ttattgatcg tttcaccaga ctactttgaa gttatggcag
    42001 cagatgaaca agtgccagat aacgctatgg tatttgatga tgttgctatt acagtggaaa
    42061 aagcagacgg ggaaacttgc gatcgctgtc gccaagttcg taaagatgta ggagtagatg
    42121 aaaaacttcc tcatctatgc ggtcgttgtg caaaaatcgt tgaagacttc tatcctgaag
    42181 ctgtagctga aggattcgaa gaaaagtaaa agggaaaagg gggtgtgaca tgttctttgt
    42241 cacaccccct tttgttatca atcgtttaat tttccacgtt cacgatacca gttatctggt
    42301 tgccagatcc attcgaatcc gtctttttca agtagttcga aagctgcttt aggtcccatt
    42361 gatccagctt tgtagttggg aaaatccggt tgtgtttggt cccaagcttt tcgaatgaca
    42421 tccacgatat gccaagattg agcgacttct tcccaatgag agaagttcgt tccatcacca
    42481 ttcaacgcat ctaatagtaa tttttcgtaa gcttctgggc tattttcaac catttctgca
    42541 ctatttctaa attccaattt gattggttcc gtttcaaatc cttgccctac ttctttccca
    42601 ttcaaggata aagaaaatcc ttcagttggc tgaatataga tcgttagaac attaggtgga
    42661 agtgtcgtat cgtcacatgg ttcatcgaca gatgttttga atacattaac aggaacttgt
    42721 ttgaatacga tgttgatccg agtccctttt tcagtcaaac gtttgcctgt acgtacatag
    42781 aaaggaacac ctgaccaacg gaagttatcg atagtgaatt tgcctgcgac gaatgtttca
    42841 gtctctgatt gagcatccac tttgtcttct tcgcgatagc ccttgaattg tacaccatcc
    42901 aattcacctt gagcatattg cccgcgaacg aagttttcta acacttcttc ttcgttataa
    42961 atgcggatag ctttcaatgc tttgatcttt tctgtacgga tttctttttc ggaaaatgct
    43021 actggcggtt ccattgcaag taatgctaca acctgtaaaa tatgattttg caccatgtct
    43081 ttaagtgcgc cactatgatc gtagtagccc ccgcgatctt ctacaccgag gttttcgcca
    43141 aaagtaattt ggatattgtc gatatagcga ttgttccatt gagcctcaaa aatattattg
    43201 gcaaaacgga tagctgagat gttttggatc atttcttttc ctaaataatg atcaatcctg
    43261 aaaatatctt gttctgggaa tacttctctg atttgctggt tcaattcaaa agcagactgg
    43321 taatcagaac cgaacggttt ttctatgatc aaacgattga agccattttt tgtcataata
    43381 ttttgtgatt tcaaatgaga aacgatcgtt ccaaaaaatt gaggtgccat agccaaataa
    43441 tagacacggt taccgtttaa ttgatagtgt ccatctaatc ggtcagacaa ttcttttaat
    43501 gtctgataat gcgttgaatc atttacatca tgggattgat agtaaaaatg gcttgcaaag
    43561 gtagttgctt cttcatctga aggattcaat gcacggattg tttctttgac aacttcacgg
    43621 tagtgctcat cgctccaggg acggcgagcg gttccgatta cagcaaaatg ctcgcctaaa
    43681 tttccttttc tgtaaaggcg gaacaaagac gggtacaatt tacgctgggc taggtcacct
    43741 gtaccgccga atatcgtaaa caatacattt ttttcattag acatgtggat acactccttt
    43801 atattttatc gacaaaaatc gtgctggccg ccttaaagct gacggggatt ttctttctat
    43861 cattttggat agtgatcggt ccttcataag ctgcgatgtc aacgatctca tattcttcgt
    43921 tgatattcag gtcaatagtg actaagtaat ccaacaattc tttttcatca agcactcgtg
    43981 cgatacgcac ttttgtaccg acaggatagg actccaatgt ttgtcggcgt tcttcatgga
    44041 caacttcctc ttttttagga atcgatcctc catgaggaca atgttcagga tgattcaaat
    44101 agttttctaa atgatctgca agatgttccg aagtcacatg ttccaatact tcagcatcat
    44161 catggacttc attccagcta tagtctaaat gttcaactaa aaaaacttcc cataagcgat
    44221 gtttgcgaat cagactgcta gctttttgca gtccgcttgc agtcaattgt acaccttgat
    44281 aaggggaatg ttctacaagc tcttctttca caagtttaga aatcatttca ctgacagatg
    44341 cagctgagac atctagacta gatacgattt gtttattgtt gactttcgtt gtatctccac
    44401 ctagttctaa aatgattttc aaataatctt ctcgatttgg tgtcatattc gatcatcctt
    44461 tcatggtaaa aaaccatcat tagtaagtgt aacaaaaaaa acgttaattg actatttttc
    44521 taaataaaaa acaaaggatt tttagacgtt tttacaacaa aaaacgaaag atgatagaga
    44581 agactcattc tttcgtttat aaaggatata tatatacatt gggagggatc tatttttcag
    44641 ataacaactt atatgaagtg tctgcagatt cgtcataaag agtttgttcg ggataagaaa
    44701 agataagata aaaaccatac tgatcacgta cgactaaacg atattcatct atttctacca
    44761 cagatgtgcc aagagactga ccgttgatca aaaacgtgta atcagatgta atctgtaatt
    44821 gttgtttttg ctggctatca ctaaagaacc atgtaccttg atactttgag agtccttctg
    44881 acttttccgc ttgttttttc tttttcaagt aaataaaact tgagagaacg gtaatgagtg
    44941 aaccaagaaa atagatcatt ttttttatca ccaaatcact cctttatgag aaaataatcg
    45001 catagacata ttctttcttc tttatttcat tgtaccgaat aaaagctaaa atttctctaa
    45061 gactttcgac tggttttttt actgtttttc tacaaattat gataggatac atagtaggaa
    45121 gaaaggtgac ataatttgaa gtatcagcaa gtggaaatag ctttttttat tgaccgcccg
    45181 aatcggttta tagcacattg tatgaaaaaa gacggagaaa taattattgc gcatgtcaaa
    45241 aatacaggta gaggaaaaga ggtcctgata ccaggcgctg aagtggctat tgtatttgct
    45301 cctggaccta aacggaaaac cgcctatgat ctgattgctg taaaaaagaa gggtgactgg
    45361 tttaatatcg atagtcaatt gcctaatcgg ctggcaattg atggtatttt agacggcacg
    45421 atccttttac caggattaac tggtccattt acggtataca agcgtgaagt aacttatctt
    45481 cactccaaat ttgatattta tttagagacg gtggtcggac aaaaagcatt tgttgaagtc
    45541 aaaggtatga cacttgaaaa taaagcgatt ggtgcttttc ctgatgcgcc cacactcaga
    45601 ggattgaaac atataggaga attaacgtat gccgcacaag atggttatgc cgcttatgtc
    45661 ttgtttattg ctcagttcga acatcttcat ctggcaacga tccatgaaga aatgcaacca
    45721 gcactagctg atatggttcg acatgcgcag caaagcggag ttcaaatcct cgcctataat
    45781 tgtcaagtat cggcagatga ggtaactgtc aagcaggcca ttccatttga tgtagatatc
    45841 ccttttgaag atcctataca atagaaagaa ggtaaaataa tgatcaactt aggtattatc
    45901 ggaacaaatt ggattactca tcaatttgtc caagcagctt taagcacaaa aaaatatgaa
    45961 ttgacagcgg tatattctag acatttggaa aaagcacagg aatttggttc tcattatgaa
    46021 ggggatatcg aattcgcaac agatttgaag acttttttca atattactca tatggacacc
    46081 atttatattg cttctccgaa tagtcttcac tttagtcaag ctaagcaagc aattttggca
    46141 ggaaaaaatg tgatagttga aaagccagct ttttcgacgc caaaagaaat ggatgaaatc
    46201 atccatttgg caaatgaaca caatgtgtat ttttttgaag cagcaagaaa tatccatgaa
    46261 tcaggtttta aaaagattgc cgattactta ccattaaaag acgagataat cggtgcaaat
    46321 ttcagctata tgaaatattc ttcgcgctat gaccaagtat tagatggaga agaaccgaat
    46381 atcttctcga ctcatttctc aggtggtgca ttgatggatt taggtgttta ccttgtatat
    46441 gcagctgttg cttggtttgg aatgccaaaa gaagtccatt atttcccaag aaagatttct
    46501 actggtgtag atggtcttgg atgggggatc ttacgttatg agaattttga tgtatcgatc
    46561 cagccaggta aaatcggtga ttcttattta ccgtcagaga tttattttga ctcaggaacg
    46621 ctagtgatga atggagtcaa tgcaattgaa caagcacaat ttcatgatcg cgcgcataaa
    46681 gaaatcattg atttggcggt aacagctgca gaaaatccaa tggcagatga agcagaggat
    46741 tttgccaatg tcatggctca tccgaaagat ccagcttggg gattgttgta tgaagagtgg
    46801 atcgagctag ctagaaatgt gaaccaagtg atttatgatt taagaaaaaa tggcggcatc
    46861 aaattcgatg cagataatga ggaagatttt taatgaacga atttgtacaa gtatttcccg
    46921 aaaattggca gaaaaaatat gaggataaag ggtttatctc accttctctt attcaacgag
    46981 cagtttttca gccactaagt aataaacaaa gtatagtagc ggtttctcct acaggttcag
    47041 gtaaaacact ggcttatctt tggcctctac tactaaacgt ggaaccaggt gaagcaagtg
    47101 cgttggtcat ttttgcttct tctcaagaac tagctattca agtagcagat gttgcacgtg
    47161 aatggggaaa agacaaagag ttgaaagtcc aatctttggt gggcggagcc aacgtcaaac
    47221 gtcagattga gggtttgaag gaaaaaccag aaatcttgat tggtacacca ggaagaatat
    47281 tggaattgat gaaagcaaaa aaaataaaag cacatcaagt gaaaacaatg gtatttgatg
    47341 aagcagacca gctatttgac gctgggaaca gccaaatcat tgatcaaatt cttcatcaag
    47401 ctccaacaga gtatcagcta gctttttttt cagcgacagc agatcgttcc cttgaaagca
    47461 ttgaaaaaat cactgggaaa acgtttgaga caattgacgt gacagcagag gacgattctc
    47521 gaaaaggact gagacattac tttttacgtg taccgatacg aaagaaagat gactacttga
    47581 gacgtctcac gcatatagaa gattttcatg gtctgatttt ctttaatcaa ctgactgaat
    47641 taggcgtaat ggaagaaaaa ttgctgtata gaggtgtacc ggtaggaagt ctggcctctg
    47701 atcagaacaa gctactccga aaagcagcgc tagaacaatt caaaaagaaa atggtcagag
    47761 cacttttgac cacagatgtg gcggctagag gtttagatat tacaggtctt ccttatgtag
    47821 tgaatgcaga agttccgtta agtgaagaag cttatttgca tcgttcggga agaactggtc
    47881 gaatgggtaa tgaaggaata gtaattacac tcgtacaaga taataatcta agagatttaa
    47941 aacggctttt acgtccatca aatataacac ttgaagagat ttttttatac ggaggtaagc
    48001 tgcaaactga gcagccaacc aaagaagatg cagctcctgc agtaaataaa aagtatgcga
    48061 aaactttttc tggaaaggag cagaacccag aatataacaa agaaaaaata agaaaaaaag
    48121 ttaaaaataa atcaaaaaaa gagagaaata aaggagcaag gcgcaaataa gcgccttttt
    48181 atgctatgat tatgaaaacg ggaacaaaat tggttgccag aggaggggtt atgtgaaaga
    48241 acgtcaagaa gagatcttgc agctattgac agaaaaccaa caaggattga cagcaagtga
    48301 tgtagctgag cgcttaacta tcgatcgaag caatgcaagc cgatatttaa gtgaactata
    48361 caaggcccat catattgtaa aaaccgctgg ccgaccagtc gtttactctt tgccaacgga
    48421 aaagtcaaaa tctgatgaag tgcatgtcga ctcttctacg caagtgactt ttgaaacact
    48481 cgttggagaa aatgattctt taaaagtcag catacagcag gcaaaagctg cgattcttta
    48541 tccaccgcgg gggttgcata cgattatttt tggagaaact ggtacaggga agtcgatgtt
    48601 tgctgaatgt atgtatcatt ttgcaatcga ttcagagatg ctttctgcag atgcgccatt
    48661 tgtttctttc aattgtgcgg attatgatca aaatccgcaa ctgctctttg gacacatctt
    48721 tgggatcaaa aaaggggctt acacaggagc agctcaagat agtcccggtc taatagccaa
    48781 agcagacggc ggtatattgt ttttagatga gatccaccgt ttaccgccgg aagggcagga
    48841 aatgctgttt actttcattg ataaaggtat ttaccgtccg cttggagaaa gtgcacaagt
    48901 acatgaagca tctgttcaga tcattggggc gacgactgaa tcttcagaaa gtttcttatc
    48961 tacgttcaat cgacggattc ctatggcaat caccttgccg aatcttgctt cacgttcact
    49021 ggatgagcgt tatgaaatca tctctctttt tatcaaacaa gaagcgaatc gtttgaatca
    49081 acgtatcgat atcgaaaaag aagcgattct tgccttcatg ctttatgatg cggaaggaaa
    49141 tatcggtcaa gtgaaacgag acttgaaact agtctgtgca aaatcttttt tacattaccg
    49201 tactcatcat gagaaaaagc taatcattcg aaaagaagaa ctttcccttc aagtacaaaa
    49261 aggattactg aaaatcaagg aaataccgga acgtctcgac cgattcatgg acagcaaaag
    49321 tcagtatttg acatttgaac caggatttgc tgatgttgtc tggtcacaag atccagaacg
    49381 aaacatgcag gtctataacg atattgagga aaaagtcact tctctttccg aaaccggtgt
    49441 ggagaacatt gatctagaga ccctcatttc aaaagatgtg gatgcttatt tccagacata
    49501 tgtcaaagaa ttgactaaaa gttcgattcc caaagatctt ttgccagatg aaatctggcg
    49561 gttaaccaat caattgtatg atgtggctga aaaacggtta gaccgtattt ataatgaaaa
    49621 agctcgtttt gcttttgctt tgcatctgca aagtacattg gatcgtgtga gagaaggtca
    49681 tatgatcgtc cacccagatt tgaataacgt acggaaaaat tttaagaggg aattccaggt
    49741 agcaatcgat ctttcaacga tcattgaaga agaagaacaa gttgagattc cttttgatga
    49801 aatcggcttt attagtatgt ttctttctat caatctagga gaaagtgagc ctgttaaaga
    49861 aaacaaagta gatgttctca tattgatgca cggcagacag actgcttcaa gcatgttgga
    49921 gatggcacaa gaactattag gaacaaaagt agggaaagct tttaatatgc cactggttat
    49981 ggaagttcaa acaatgtatg aagaagtgtt acaatatgtc aaaaactatc aagagcattt
    50041 gacgaatggc ctactcttgt taacagatat gggatcatta aacaccttca gtgatttgat
    50101 ttatgaagag actggcattc ggacgaaagc tatcacgatg acaagtacca tgattgtgat
    50161 agaagcgata cggatggcaa gtgttggaag aagcttagaa gatatttatc aaaatatcca
    50221 gctttccttt gaatcgatcg tacgtgatca gttcaaagcg gaaaagtctg aaactttaca
    50281 gcgtaaaaaa gccgtaatcg tgacatgctt tactggtgaa ggagtagctg ccaaattata
    50341 tcagcgtatt atgccagtga ttaatcaaaa taaggtagaa ctgatccaga tgcagttttt
    50401 agaacgtgaa tcattcaaaa aacacatcga tgccttattg gaagaatatg agatcaaagc
    50461 aattgcggga acagttgatg ttgattatca aaatatccca tttttttcag cctatgacgt
    50521 ttttgatgat gaaaaactaa atattttaaa gcgtatagct gatgatgaga tcccgacagc
    50581 taaaattgtc gattcacttg ctggatcatt aagcgatgtc ttttctattg atgaactgat
    50641 ccgttcattg caaaagacag ttcagcagat ccagaccgat ttgtcgatta tcgtggaacc
    50701 tggagtagat actggaatcg ttatccattt agccttcatg ttagacggat tgatcaaaca
    50761 agaaagccat cggcaatttg agaaactgtc tattttctca aaaatttatc gtttggaaat
    50821 ggatatcgtt cgggcaaact tgatggcact agaacgaaaa tatcaggtaa aaattccaga
    50881 agatgatatc gcatttctta cacaaatgtt tcttgaaaat aaaataaaaa aatgaacaca
    50941 ctaatcatac tgtttacaca ctaaacatct gtgtgcgcac tataaaaaag agctaaaaag
    51001 catgaaaacg ctatttcagc tctttttttt attggcatgc ttcttgcgtt atataaaagt
    51061 gtaaaaaaat aaaaggagtg ttaaaaatgg caaaaaaaac aatcatgtta gtttgttcag
    51121 cagggatgag tacgagttta ttggtcacaa aaatgcaaaa agcagcagaa gaaaaaggga
    51181 tggaagccga tatttttgcg gtctctgcct cagatgcaga taataattta gaatctaaga
    51241 atgtcgatgt attattatta ggtcctcaag tacgtttcat gaaagctcaa tttgaacaaa
    51301 aacttgcgcc taaaggtatt ccattagatg tcatcaatat gcaagactat ggcatgatga
    51361 acggagaaaa agttcttgca caagcagaaa atctaatgaa ataaatcaag tatgcagttg
    51421 ggggtataac aacgtggaag atcaacaaaa tctagaagcc atcatggggt taatcatgtt
    51481 tggcggtaat gcaaagagcg atgcaatgga agcgattgcg gctgctaaaa tcggtgattt
    51541 tgagttagcg gataggaaaa tcgctgatgc agaagaatca cttatacaag cgcatcatgc
    51601 acaaacagac atgttgacac aagaagcaca aggaaatcat atgcaagtga cattattgac
    51661 tgttcacagt caagatcact taatgacatc tattgcgttt actgatttag caaaagaaat
    51721 catcgaactt tatcgtcgcg tatacagcga ataaatacaa cttctttttt gaacggaaga
    51781 agaaaaattt ttgaacggat tttttatttt gttataagga gaactctctt tatataaaaa
    51841 acttatagga ggaagtaaaa aatgaacgga ctatcaagtt ggatggagaa atacatcctg
    51901 ccggttgccg caaaaatcgg agcgcaaaaa catttagttg ctttgcgtga tgcttttatc
    51961 ggcatactgc ccgcaacaat ggcgggatca gtcgctgtaa tgatcaatgc aattattcgt
    52021 gatttaccgc aacagtttaa cagtacctat gctgacagtt tagcagcaga caaaggaatc
    52081 tttgccgtat tgaatgtcat catcggaatc aatggttttg tctggaacgg tacactagca
    52141 atcgccggat tgatctttgc cttttcttgg gggtataatc ttgcccgagc ttatggagta
    52201 aatgatctag ctggggggat cgttggttta gctaccttga ttcaaggtat ttcctttggt
    52261 ccagcattat cagcagcatt agatgtgaat gttccttcaa atgtcgcaga tgcaatcaat
    52321 agttctgaga ttggtgcaac gattgcagat ggcacactgt cagttggatt atggggttgg
    52381 ctaaaactag atcatttgaa tggaaacgct tattttacag ttatgatcat gggagctatt
    52441 tcagtcatta ttttttgtaa attgatgctt gccaacatta cgatcaaaat gcctgattca
    52501 gtaccaccag cagtatctaa agcatttgca gccattttac cagcgacgat cgctttatac
    52561 gtcattgcta ttatcaatta tatcgtaggt cgtgtagctg atgggcaact gatcattgat
    52621 ttggtgcaaa aatatattgc agaaccattc ctaggattat ctcaagggtt gggagcagta
    52681 ttgatcgtca cagtatttgt tcaagtattc tggttctttg gtattcatgg atcaaatgta
    52741 ttggcaccag tgctagaggg aatctgggga caagcacaac taatcaatat tgatattttc
    52801 caaaaaggtt ataacggaaa aactggtaca ccagccgtgt tagatgcaat cgaagatgga
    52861 aaagcttata tgtgggtccg cggatcgttc gatgcttttg catggtttgg cggatcaggc
    52921 ggaacgatcg tcttactgat agctatcttg attttctcta aacgtgcaga ttatctaaca
    52981 gtagctaaat tatccattgg gcctggtatc ttcaatatca acgaaccagt gatgtttggt
    53041 ctgccaatcg tattgaatgc aatcatgttt atcccattct tgattgctcc agtagtagca
    53101 acagcaattg gatggacagc tacttatctt ggcctagtcg ctccggtatc gcagcaagtc
    53161 acatgggtag taccgccgtt cttattgtca ttcttagcaa caggagcgga ttggcgggca
    53221 ccgatcgtaa cattagtatg tatggtcgtg actttcttga tttgggcacc atttgtcatc
    53281 tctgcaaaca aaatggaccc tgccgcaggc gaacaacaat aagatgaacg tgaggagcgg
    53341 gacgctttaa gtttcgttcc tcataatgaa ttttcgagga ggaactgaaa tgattacaat
    53401 tgccagtgca atgcaacaag atgaaatcaa agaattgtta gaaggataca atgaagaagg
    53461 aatgactttt acatttaaag aaaaacaagg aatcaagctg ttctttgaaa caagtgcaga
    53521 agatccggaa gttgcggcta aaaaagcaaa ggaactaatc aaagcacagc cttggggaac
    53581 agtcctttat tttcaatcaa cagctgttta gaaaatggtt taaaaagata ggatggttga
    53641 gatgataaaa aacggtttat ttttatgtag tattggttct ttgatcgtgt tgtatagttt
    53701 gaatccacat tcgcaaaggt atgatttgta tagtatggtc acaggtcttt ttctaacagg
    53761 attaggaatc tatttcttca tgaaggggaa aaaaagagaa gaagcaaagg agaaaaataa
    53821 ctaatggaaa tcacgaaaaa attaaatatt ccagcatcgt ttttttacga taaagttatg
    53881 gactctgtcc ttttcgatgt acgtaaagcg accggcaaat cagtaactag aaaacagctg
    53941 aaaaatttgg agtacgtcaa acaattctcg caaaataacc gggctcgcat aaaaatcgaa
    54001 gaagtcattg aaaaccagtc ttataagttt cgtacatcga caacgaagaa tgaattcgtc
    54061 gttcattatc aaatcaaacc attggacgat tcgacctgtg aggttcatta cacagaaaaa
    54121 atggagtctt atggcatgct tcaaaagttg aatgatatgc ttttaggaac aatcttgatg
    54181 tattttaaac ggagacgttt caaaaaaatg ctagatatga tcgaagcaac gtattaaatc
    54241 aatgaaacat ggtactattt agttattgaa aaatgaagta agctagaagg aatttttcat
    54301 aggaagatag atctttcctg cgaatcctca ctagcttttt tgtaggaagg ggcagcaaaa
    54361 tgacaaacaa agtaagagag ctaggtgtat cttcgattga ggaaatgttt gatttagcca
    54421 cttatgcatt taatggggca gatacacctg aaaggcgaga acgttttcgt acacttgcgg
    54481 agaattcttg gaattacgga ttttttgatg aggaggatcg gctaacaagt caagtcatgg
    54541 cgaccccttt tccagtgaat ttttacggac aagagtacct aatggccggc attggctatg
    54601 ttgcttctta tccagaagca aggggacaag gcgggatcaa tcagatcatg gaaaagatcc
    54661 ttgaagattg ccgtgatcgt aaagtaagct tatcttatct ggcgccattc tcctatccct
    54721 tctatcggcg ctatggctat gaacaatcat ttgataaaat cagttatcaa ctaaacagtc
    54781 gtgatgtgcc gtttatcaaa aaaaaatctg gaaaaataaa gcgtatggat tttgaagatg
    54841 caaaagctgc aatcagaaga atttatgaac agatgccgga aaaccaacga gctggtctga
    54901 agcgcgaaga ctggtggtat acgtataaat tcaagcaaaa aggcaattac cagtttgctt
    54961 tgcattttga tgataatgag gaagcaacgg gatatatcgt ttatcagctt gcaacgtctt
    55021 cctttattat tgcggagtgg ggatttttgg atcatgatgc tttttgcagc cttgttcgct
    55081 tcgtaagttc tcacaatggt gcttttgaaa catttgaata ttcatgcggc tacggcggta
    55141 atgatcaaaa ttatctatta gaaaatccat ttgcttctgt aatgatcaca ccttatatga
    55201 tggcgaggat cgtagatatt tctttgtttt tggaaaatta tccatttaaa aagagacaag
    55261 ctgcatttgc cctacaaata gaagaagatc attatgcgaa atggaatgaa ggaatcgtgg
    55321 aagtaacaat cgaaaatgga aaaaatcatc tctcaaaagt agaacaaaca aaactcccaa
    55381 tcgttcgagg aagtatccaa catatcacgc agctattatt agggtatcgt aaagtggaag
    55441 agttggtatt ccaagaaaga atacaggtga caaaagaata tgaagaaacg ttaagctcaa
    55501 tcttgccaca gcaacagcca attcttaatg actatttttg ataaaaaacg ggtgatgaca
    55561 atatttttgt caccaccctt ttgtttttca tttggcattt gaaggaaaat gttaaagtaa
    55621 atcctctttt ttcgtaaatt tgaatttttt gttttctttt gttttagggt tttctttttt
    55681 gtggtcttgg attgcttctt tcgtaatctt ttcccgattt tttttagatg aatctaagcg
    55741 ttctgcgtat actttttctt ttggcttatc attcattgga aaggacctcc ctacattatt
    55801 tcattctacc tctagtttat catctgttaa ggactagtgg aaacgttttg cctaacttat
    55861 aagctgattt ttttagcaga taagcttgca agtaaaaaac aaacaagcta caattgattt
    55921 attgaaattg ttcctgtagc tcagtaggat agagcaatcg cctcctaagc gataggtcgc
    55981 tggttcaatt ccagtcagga acgtataaat aacccctgta tcctttgcgg tacaggggtt
    56041 tgttttgtat ttgtgccaaa aatgtgccaa actagttatc atttttatat aaactatcga
    56101 acacagtatt gattttttct ttatcctgat cttcaagctc tcgaacaata tgaagataag
    56161 tagacattgt agtttctaaa ctgctatgtc ctaaacgttt cgatacgcta agtatattta
    56221 ctccttgata aagtaaaata gatgcatgtg tatgccttag tccatgcaaa gtaaattgct
    56281 tttcaatccc taattctttt aattttttgc gcaaatattt gctgacggcg tttgatgaaa
    56341 ctaatccatt ttttaagttg aaaaaaacaa aattatgagg gtttttgatt tcaaaattct
    56401 cgaataattc tttttgattg attttaaact tttttaagag atcaatcgta tgtttatcaa
    56461 tggaaatttt cctatttgaa gtttcgtttt ttgtttttcc ccattcattt aatttataat
    56521 tccatgtttt attaatagtg atgatttgat cttcgaaatc gatatcttcc catgttaatc
    56581 ctagaagttc agcaaatcgc attccagtgg caccagcaac taacacgagc ataggagaag
    56641 agtactgcgc agaaaggttt tcttctacga gtttcattaa agatttaaat tgatcataat
    56701 ctaaatattt atcttctttt ggcttcaatg aatcttttcc tttgattact gcttttctag
    56761 ttggatcaaa cggaattaat ccttcttcta cggcatcttt caacgacgct ctaatatggt
    56821 tattaaactt aataacggta gattttacat ggtctttagc atacttattt aaaaagcgtt
    56881 gatatcccac tctatctaaa tcagaaatca ataccgctgg catatatttc tttatgttca
    56941 ttaacgtatc ttcgtatttt ctataagtga taggagatac tgttccttct ttataaagtt
    57001 gcatccaatc ctcaaagtaa tctgataata atagattttt gcgatcccct ttaaggcctt
    57061 tgttcaagtt atattctaat tcgttggcgg catcttttgc ttctcctttt gtcttaaatc
    57121 ctgattttct tatcttcgtg tattttccgt catctttttt gtatgaaatt tcgtattgcc
    57181 aactatttcc acgtttgact aatcttgcca taattgaatc agctctcttt ctctgataca
    57241 ataggaacta taaagaagcc cattgtttgg gttttattat tttttgcaca tcctttttgc
    57301 ttgccggcgc aaggatgtgc tatttgtcgt tttaatggta taattggatg tgtattagat
    57361 catccaatca gaggtgttta ttatgattaa agtgattttt aaaagaataa ctgaacttcc
    57421 agagtttaga ttatttgttg attattggta tgtctggttt tttattgttg cattgctgat
    57481 aggtctagat gtcatattag aaagaaaact taagtaagag ttgagttaat aaattgaatt
    57541 cctaaatgag atattttgta gcccatattt tgtttgccga catcacctaa tactatggag
    57601 ctaatcgttt tttctaacag accaaaatca gataatctat ttaagctacc atctattagc
    57661 tcttgtgaat agccagacat gctgatattt ccagtgaaat tttcgtttcc acgactcatt
    57721 aagcatgcta acaattgaat ctcaatcgat gttaattgat tcagtacaag aagataatac
    57781 tcctcgttat cccatgaagc gttgttaatt cgaagtaaac aattcttata aagattttta
    57841 tacatatcta ttttattttg tgcctttgat ttttctacct cgtcatttat cccttcgaat
    57901 attccaatga gttggtcctt gttctctaag ttgaaaacat cttctggaat ttgatcgcga
    57961 atgttttcta atgattcgtt taaatttttg tagaatttct cgatgcgttt gaaacgcttc
    58021 tcgtttttag acccaaaata aagtgactgc acaacgccac caatataagg aattgctcca
    58081 ataccgcctt caactattaa ttcaagatat tcttttttgg ttagtttttc attgctatta
    58141 tccatagtta cctcctattt tgtcatttcc tttacaagca ttgtgactcc tgatggcact
    58201 cttttgtata ggttttatta ttgtgcacaa tctaactctt agtggggcgt ggttcattta
    58261 ttttttactt actttactat taatcatatc ccattgagca taggattttt ctatgttcga
    58321 tcctcttgaa ctaatttctc ctgtaaaagt tactttatcg ccctttgtaa aggtatcagc
    58381 attgtttaag tccttcgcaa aaattacata tgaaacttta ggtgttgcag aaatatcatt
    58441 ccaactttta tcatcgtact ctttgtctgc tataatggct attctagtag tcattgattc
    58501 gataacagtt ccttcaaaag tatatgtttt accactaata tatttagtaa aagctgtatt
    58561 ttgctcagta gctggagtaa tagaataata actatctaag aaagcacccc agtcatgatt
    58621 atttgtctct aaaaattctt caaattgagt taggctttta ttgctgctgt tagatgtagt
    58681 agtttgagta tcagatgatg agctttcctg tttgttattg tcatttgcct cgtttgatga
    58741 ggaaagcgag aaacctacgg tagtaaaaat aatcccgata ataaggagaa tcataggtgt
    58801 tttcttattt gtttttttga taaatcttac aattaacatg attaaaccta taataaataa
    58861 aacaatacca gtaaaaccaa atataccgtc cattaataga tcctctttct cttttgatat
    58921 tgaatattat aaaccaagca attctttttt cttaaaatcg aattcttctt gattaataat
    58981 cccttcatct aacaactctt tatacttttt aatttcatct gcacttgaaa tttgtgtttc
    59041 tttggaatta ttatctaata tagattgttg cttctctata tattttttta aattttccat
    59101 ttcattccaa tatttttttg taaacataac ggtgttttca tctttcgtgg ccgctaatat
    59161 acctccgcga ctttcgtttc cgcctagcaa ggtaaattgt atataaccat tactcatacc
    59221 tggttttttt aattgtacgg ctgatatatt tttaaagggg atagtttttt ctcctttaat
    59281 accttgatta actaaattta taaatccttt tctaataatt gaaatagaat catcagttac
    59341 tttaatcaag gtttttcctg gagattttat taaaatctct ttttccattt tttcttcctc
    59401 atttctgtga tatgattttt tttgtagaag ctcatatatg aggaaagagc ccgtgttgca
    59461 gcacgggctt ttttaatgtt ttgctgaaat cggttttttt aataattctt gatgtattca
    59521 tacatattgc cttgcgtaag aatatttttt cttaaaatag cattggcaga cagcataaca
    59581 agtgtatctg agcttattct gaatagaata atactccata aatttttcga gattaaactg
    59641 agattcatca gtcagttcgt tctcaatata gatatttaat aaaattagaa tagctatttt
    59701 atctgcttct gtttcaaatt ttgagtgaaa agttgtagaa gtatcgtaca aaactgaaaa
    59761 ttcaaaatga gaggcgctga aatgtgcaag ttcatgagat aaatgaaagg cttctgcagt
    59821 ttcaccgtat agattttcat tcaaaaaaat gattctgggt tttggatagt agaaaccagg
    59881 ctctttcatc tccatataaa ctactttcaa attgtattcg ctcaacattt ctttcaattt
    59941 caaatacata caaaccatca ctccaactat tcattttcct ctaaagcttt agcaattgca
    60001 atcgctttac gcattgtctc cttagatatt tcttttccat caaaagaaaa aacagtatcg
    60061 tcttctgata aatccacatg tttaggggtt tctctttctt ctctacctag aaggtagtct
    60121 acagagacat cgaaatagtc agcaatccga cttaattcat ctgaattagg agtattattt
    60181 ttccactttg ctagataacc gttagaatat ccaaaattaa tttctaactg ccgtatagat
    60241 atctttttcc tcttcgccaa gtcttttatt atttcatagg tattcatcga taaaacaacc
    60301 tttctaaatg tttacaaaaa aagtttagaa aaatacgcag aaataatttg actaattctg
    60361 agtaatgagc tatactatat cttgtaaaca gatttaacaa ctaaaaagac aacaaaaaac
    60421 actattgata tgtaaatgca gaccgccaag aaagctttaa aatcaatgtt tttatgtctt
    60481 atttaattat gctcttagta tagagtatta ctcagatact gtcaattgaa tttagaaaaa
    60541 agttgttaaa tttgtttacg aatataaaag aaaggaatga gaaatatgaa cacaccgcaa
    60601 atttttaatt tcgaacaaaa cgaagttcgg acaattttag taaatgatga accatatttt
    60661 gtaggcaaag acgttgcgag tgttttgggt tattcaaaca ctaaagatgc tttgtcgcgg
    60721 catgtagatt tggaagataa gatggggtcg cgaatcacga cctcaggtca atcaagagag
    60781 atgacaatca tcaacgaatc tggtttgtac agtttaatct taaaatcaaa acttccctct
    60841 gccaaaaaat ttaaacgttg ggtaacaagt gaagtgttgc cagcaattag aaaacatgga
    60901 ggttatctaa ctccagaaaa agtagaagaa gctttgctta atccagatac aatcattcaa
    60961 ttagcaactc aactaaaaga agaaagaact ggaagattaa tcgcagaaca aaagattgca
    61021 gagtacgaac ctaaaatctc ctatttagat agcatattat cttctacaga ttcagtaaca
    61081 attagtcaga ttgcagcaga ttatgggatg tctccacaac agatgaataa attacttcat
    61141 aaactaggta ttcagaaaaa agtcggtaac caatggttat tgtgcaaaaa acacatgaac
    61201 caaggataca caaaatctca tacaactgag atcccgaaag ccgatggtgg cactaaaatt
    61261 gtaatgaata ccaaatggac acagaaaggg cgtctattta tctacgaatt actaaaaaaa
    61321 gaaggatatt accctcaaat ggatttagag gaaattggtt agaaaggagt tttagtatga
    61381 ctgacattgc agaaatcact caacgagata gagaaaaaat caaagaatat gtcgaaagtt
    61441 caaagttctt aacttacacc atgcttgctg aaagatttgg aattagcaaa agctacttat
    61501 ctttaatttt aaacggtaaa aagacttctg cagaagcaaa cagaattata gattcgatta
    61561 tcactatgta cgaattgtaa agggaggaac agctaatgca atatctagaa gcaaaaatcc
    61621 caattccaga aggctatgta attatctccc aagtggatta tgaggagtta aaaaaagctg
    61681 atgatactgg tagatggatg acgttgccag aagtgctaga acggattaac agaaaatatg
    61741 attggtttac ttctagagtt ttaaagaacc caagatatag aaatattatc gatatcgaga
    61801 aaaacaaaaa tggatttgtc tattatccag ttgaaggaag agacacatat ctatttttaa
    61861 gaagtaaaac acttgaattt ttagaaacaa atttttcgga aatcttaagg aggcaagcgg
    61921 atgggaaaat ttaatagagc gctagtgttc agcgcaccgc taatcatcta cgctttagga
    61981 ctttggggaa gcaggcaagc gttgatagga acgattgttt acatggtttg gatttttatg
    62041 gggcttgatg aagctgaagc tgagtacaga gcgaaaaagc caaccgaggg ggctgactaa
    62101 aaatgaatag aaaagagaaa ctagaatgta tattactatt actcagttta attctttcac
    62161 taatttctct attgggaagt ttgtattttt gatatcaaca attttgtgga tttgggttct
    62221 atttagagta aatatcattt ttgtttggtg attaaggagt ttattaaaat taattttccc
    62281 tacttcaaat gcaaggtaac aagatatagc acttttagga ggaatattta gcggtacagc
    62341 ttcagagtat attctattat catcgactga tcctccttta gcaattaatt tcttaaatgg
    62401 agtagctgac catctgcggt ttaagttagc ggatgaaagt tctaaattaa ctaacatagc
    62461 tggttctgtt gaatagttag aaatgattac ttttgtataa atcatatctg cagcgaagta
    62521 agaagcatta agttcaactt ctagttgagg gcgcattcct tttattttta tccctgttaa
    62581 aaacgtactc aatataaaac ttattattga catccattga aaaattgtta agtgaaaaaa
    62641 attcaaaata aacaccacca gtttttaact aaattatacc aaaaaggaga gaagaaataa
    62701 tgcaagaatt agtaattttg aaaaataaag aagctgtgac tacgagctta caagtggcag
    62761 aaagcttcga gaaaaaacat caacatgttt taagagatat tgatgcacta aaaaaagatg
    62821 tgtccaattt tggacagatg tttgtagaag gtaatgaacc agattcatat ggcagaaatc
    62881 gacgagtttt cttcattagt agagatggat ttttcttgct ggctatgggg tttacaggaa
    62941 agaaagctat ctacttcaaa caaaaataca ttgaagcatt caacgaaatg gaagatgtta
    63001 ttcgcaagaa tactgttcct caaacaattg aagatatgat gatctatcaa ttagaagaaa
    63061 tgaaagatgt taaaaaagat gtttccatgc ttaaagatac tatgcgaatt agcggacaac
    63121 aagagtttga aattaagcaa aaaggaaata tgaaagttat gggagttcta gggggaaaag
    63181 aaagccgagc ttatgaagaa atcagcaaaa aagtattctc aaaattttgg tctgaattta
    63241 aacgtacctt ttcaatccca agatatggcg agttacctcg taagagattc gatgatgctg
    63301 tttcatttat tgaaatgtgg ttgccagaaa ctgcgatccg tatggaaatt gatcaactga
    63361 acagacaaca gagacttttt ggtgatgaca atgaatagag ctgaagcgct aagaataggg
    63421 acggcaattg ctaattgctg gtggaaatac tataaaccaa tcatcctaag ccaacaacat
    63481 attgacaagc aaaaagcatg gcaacaaata aaaaagtgac tccgccggca agcaaagagt
    63541 cacaaagaaa acacatcata aggagatttt agcatatgga aaaagaactt tccactctag
    63601 atcaatattt gattgatcct gattggggca agccgaaaat tgaggaaaca agtggtcgaa
    63661 aaatcagacg aaatcttttg acgaatgaag aactagcttg ggatcaagat gatttaggca
    63721 accatgtaac tatttgggat catgtttatc ttatccatct atcgaagcat tcgaataaac
    63781 ctgaatatat ttacgtcatc gaagatggct tgattgatgc gctagaagag tacgacagag
    63841 ataacttgat tgatatctct tattacggac caggtaagaa atacattgct gaaatggagg
    63901 cagaatttga tgagtgaaat caaagggaca acgaactttg aaaaactttt tagtcgtaag
    63961 ttaaataaaa ttctcaagaa aaaaggaaat tttgattatt tatcttgggc tcacgcgtgg
    64021 gagattatga aaaagaatga tccacaggca acggtaacta ttaatgagta caaacactac
    64081 agggttgttt ctggaactca tcaagacttt cttgttgagg aatataaacc ttttcttatg
    64141 gatgaaactg ggacttatgt atctgtctca gtaacggtta aaggacacac ggaaaccgaa
    64201 ttatttcctg ttttagatta tcgaaaccaa ccagttgtta aaccaaatgc aatgcaaatc
    64261 aataactcat tgaagcgatg ctttgtgaaa gcattggctc tacacggact gggattatat
    64321 gtatttcaag gggaagatat tccaacacca cctagaatcg atacaaagaa attaaacatg
    64381 ctagagacga ttctagaagc tttcaatgag cagatgggta aagatatgac caaaacctta
    64441 atcgaatatg ttaatgagca gacagataaa ttagggctct tagctgataa cgttgaaact
    64501 attgaacagt taagctatga gcaatgtgcc ttgatggagc gagcaatagc agctaagaga
    64561 aaagaattag ataagaagtg atatgagtgt ttaaaccatt aatcgattca tattcagcgg
    64621 ttctgaaaaa gttcaaagga aaagacataa gcgcaaccat caatgaggaa gtgaacattg
    64681 atcgactaaa gacgatgtat gacggctacg atggtgatcg agtcattgaa attcgtttta
    64741 ttgatcctag acgtttcacc gtacagcaac gaaacttcat ctatgcgctg ataggcgata
    64801 tttttatcga tacaggcatg ccaacggact tctggaagga attcttctac tttcgttttg
    64861 aaggtgtcac agggcgcaaa ataagcctga aagacgaatc gaatacaact gtgagtgatg
    64921 ccaatgtctt agcaaatatc atcttagatt tcatctttga acatcatatt cctttcaaag
    64981 aaggctatga gattttacct gcgaatcaag aatattactt ctacaaatgc atcacaaaaa
    65041 gagtctgctg catctgtggc aaaacaggag ctgacatcga tcactttgac aaagcgctag
    65101 gaagacgaaa gcgcaaagaa gttgatcatg cagagtacac atttgcagca ctctgcagaa
    65161 tccatcacac agagaagcac aaaataggtg tgattaattt caaaaataaa tatcaaatca
    65221 aagggatcaa attaaaccag aaaacaatca aaaagttaaa tattggaggg gaaaaatgac
    65281 agaacatcga agttattatg cgattatacc agccaacgta aggtacgaca aaagacttaa
    65341 accaaatact aagttgttat acggagagat aacggccttg tgtaatgaaa gaggcttttg
    65401 ttgggcaggc aatgagtact ttgcagattt atatggtgtg aataaagaga ccatatcgcg
    65461 atgggtaagt gatttgatta agtttggata cttgaatcgg gaaatcattt acaaagaggg
    65521 taccaatcaa ataatcaata ggtacctacg aattaatcaa taccctattg acgaaaaacg
    65581 caatacccct attgacgaaa aagtcaaaga taataataca tctattaata atacatttaa
    65641 taatacaaaa gaatatataa gagagttacc gccttcgaaa aaatcgaagg ctaagcccgt
    65701 ccgtcataaa tacggagagt ataaaaatgt tcttttgtca gatgagcaga tggagaaact
    65761 caaaacagaa ttccctaatg attaccaaga gcgaatcgaa cgactgtcag agtattgtga
    65821 atcatctggt aagacttata aaaactattt ggcaactatt cgaagttggg caaggaaaga
    65881 aaaaagtgaa cctaagaacg caagcagtgg atacaagcgc acaggaagac gagagaagct
    65941 tcctgaatgg gcaatcgacc aagaagccta tctcaagaaa aaagcgctag aacgagctaa
    66001 tagacaatca aaagcaccat tctaagaggt ggaaaaatga agatcgatta tctagaacta
    66061 attaatgaaa tagcgaatta taaaaagggc gaggaattag acgtcctgag agacgtatat
    66121 gatcaactcg aagaagctgg aattgaagga attaagaatg atcgttcgag ttggagtaaa
    66181 ctcagatact atttcgcact ctatatcgat ggaacgcaat taagaaattt agcatatacc
    66241 aaattactat tcattgattg tgttaaaggc ttgcaaaaac atcttaatga acttgagcag
    66301 gtgtaaacaa gatggaccta aagacattta cagcacagat cgaattaatg catcaagaag
    66361 ctttaagaca aagtgtgtcg tacgaagaca agtggctcaa cacatttcat ggcggacgtg
    66421 agagcgcact tgatcaagta ctcaaattac tgaaaggaga atgtcgggat ggataagaaa
    66481 gcggcaatgc agcgaattat cgaattgact tattcagaag attggcagga agataaaaaa
    66541 atagttgcag aagtccaaaa gctcggtaaa tcaatgtgga ctgaaaagcc caaacggaga
    66601 acgccgagaa agattgcaat ctggcatggt gatcgaattc tagtaacggg taccgctaaa
    66661 cagttatctg aaattactgg tctgagcaaa aatattattt gggatagagc taggagctta
    66721 tggattgatt caaaaggaag acagtttagg tatgtggagg agaaataatg gacgaactaa
    66781 tcgcgaaagt agagcagtgg gcaaaagata agggattgga tcaagcggat ttcagcaagc
    66841 aaatgttaaa aacggtcgaa gaaatcgggg aagttgccgc ttctctagct agaaaagatg
    66901 aacatggttt aagagacgga attggcgatg tagtagtaac cttgatcatc ttggcaatgc
    66961 aaaatgatat ggatttatac gagtgcttgg attttgctta tgacgaaatc aaaggtcgga
    67021 ctggaaagat ggtcaatggt gttttcgtta agtccagtga cctgaaataa ttccattaat
    67081 ggaagaaata actgaatagg aggatagaca tgattgatgc aaaacaagtg caaaaacaga
    67141 aagatggaat gttgatgttt gaagcatatg ttctaccatt tcttaatcaa tttgaagttt
    67201 tggaatgctc tgccagcgga gaagaattgg agtatgttgt aattcgtgaa accaaagaaa
    67261 acgttcagaa gctaaacgaa tttctttgca ctattaactg ttgggatatg atagctccag
    67321 gatttttatg tccagctatg ggagaatttt tggaatattg tcgtcttgaa gatgcaggca
    67381 ctttggattt agcttatctg gtatacaact acctaaacat caacacagat catttgtggt
    67441 ttggcactgc cgaaagaaaa tgggtagtcc gctaaccacc aatatcaatg aaaaaaggcg
    67501 gtttcctgaa agtggaattg ccgccattgc tgtaaggttc tttacgcgac tcaaggtcac
    67561 agaaatataa atgcaaatct cttttgaagt gatccaaagc tctcggaaaa tggaagtttt
    67621 ttgtttcaaa gaataaatga gatttgcgtc aagaacctga gagttatttc caaaaaagct
    67681 tccaaagaac cgaatgagct aaggacatca tgtgtaaaca cataatatag ctctcctttc
    67741 acggctaatc ataacatgaa aaatattcga tgtcagtagg aaaaaaggtg aattatgaaa
    67801 agaatattaa attatcccgg cagtaacaga ttctgcaatt aaactccgaa gctgatgtat
    67861 cagtatcaac tgtagaatat tatgagcgtg gagaaagtca agcagtcaca aatgtaaaaa
    67921 tcgataacgt caacggtctt atctgtttag atgaaggcga tagtatgaat gaaattgctg
    67981 cagaccatga attatcagaa actgctttaa ttgatcaaat cgaattagct agacaatact
    68041 ttgttccata tgcagatacc tggtccaagc ataagaatga catcattttt ccagaggaac
    68101 aatgagagca actgatccag taattatcct tgaggaagcc aaatttattt ggactcacga
    68161 agagatagag caagcacgct tgctcttttc tcaaggagtt aagccgagca aagtagctga
    68221 aataatgggt caaaagattc ttgatgtcgg attgcttttg ctccatctag cagaaaaaat
    68281 ttgatttgag gtgaaaatga tgattcaact tgcaggcatc caaacaggga aaatttattt
    68341 ttctggagaa agcaaaagcg aagccaacca atggctattg aaaacttaca cgaacaataa
    68401 gaagctaagg aaaaaatatc ctgatttgtt gctaaaggat gatcagatta tgccggaacc
    68461 gatgattttg acccgtaagg agggaagttg aaactaaaaa accagccgtg tgggctggag
    68521 ttgctatttc tttttaataa tgagtttttc taaatttaat tcattctcac gagtttgcgt
    68581 ccaataatca gaataatatt ttaattgttt aagagtagga atgtcgtctt cggtaaaatt
    68641 agaaaataat tctggagaat tatctttttt taattgttct aatcctgatt ctttaaaacg
    68701 ttgttcaacg agttttacta aattgttgat attcatgata aatcaccttt ttaaatttaa
    68761 tttcgatttg attaatcgat acaagtatta tatcaaataa aaaagctgat ttagggggtc
    68821 ttacaaaaac actaaaattt tttcaaaaag aggaggaacg gtggtgaaag tcagagaaca
    68881 attcaagata gtgagcgacg aaggtaatgt ttacaaaata aagatcgtta atattaatga
    68941 atatcgagaa gcagatcaca aatatttggt tgacttatac atgaacgata aatatttggg
    69001 agaaggattt tgtggagatt cactttttga tgatgagcga attttgaagg aggaaacaga
    69061 atgatccacg aactaaaaat actaccagaa tattttgaag cagtgacgag cggacgcaaa
    69121 caattcgaga tccgcaagaa tgatcgtgac ttcaaagttg gtgatcagtt aatactacgt
    69181 gaatataaaa aatacattaa acatgaatta cctggactaa cgagaccaac atttagttac
    69241 actggtgact catacaaagc agagatcact tatattactg attacatgca gaagtccgga
    69301 tatgtagtgt tggggattaa aggggtgaat taaatgaaag tatacatctt agctatcaca
    69361 gagggcacat ggatgttccc agtcggttcc ggaaaaatct ataaatcaaa aacagctgct
    69421 tataaagcat ttgaaaaata caaaaaagaa aacggtggcg gcactaacgc aaagattcta
    69481 gtggctgata actggcatga agaaggtgaa cgtaattgat ttacctgttc attttcgtgg
    69541 tactaactat ttttatgcta gtaatcttat tcaaaaaaag atgagtaaag acgaacgaaa
    69601 aattctggcc aacttttatt tagtattaaa aatcgaacaa aatgtgtttt cggaaaggag
    69661 aattgtatgg gaaaaacaaa atcaaagatt aagaagaaaa aacgacgttt ggaacaaaag
    69721 gcaatccaga atggaacggc taagaaaaaa taaaaaagct acccctttcg agatagcagc
    69781 gcaatactat tctaccataa ggggtggcgt ttgtgagatt tcattggtta aaagattacc
    69841 aagaactaga tgagcagatt ctttacttaa agtggaatct taataaaagt aagcttgaat
    69901 tgaatcgatg ggtctgtggt gatttagcaa acgtccgcat cgaaaagaat tcgagaactt
    69961 cttctttaga agagaatatc caaaagatag aaaatgaatt ggaattgttg atcgagcaaa
    70021 aagaagaaat gttattgctg atagatagct tttctggtat cgataatcaa attgttaaga
    70081 tgaaatatgt tgatcaaatg agcttagaag atattgctga atctgttggg tatagctcat
    70141 cgtatgtcag acagcgacat gcagaaatta gaaagacatt gaacttttta gatgagtatg
    70201 aacacagaca agctgaccga ttgaaaaaag aaaacgaaat tgatttttac aatagcgaga
    70261 agtacaaaga acaactctct ttattctaaa attacactgt tcactaaatg ttcggtcatt
    70321 gtagctatgt aaacattgtt agcagcatga tattctatta gtgtcaaaaa aatatgaaag
    70381 agccaagata tcccaaccgt tttattaatt ggtatctgtg gctcttttat tcttttaatt
    70441 agtagttggc ataaagttat ttccatttat aaattgatca gctaaatcag catcataatc
    70501 agccgcgata aattgcgctg ctgatttaat aaatgcatcc atatcatgaa catctttatt
    70561 agtatgtcta cgaacatagt gcgtttcatc attaccaatc caagtagcag ctttggctaa
    70621 tctttggagt ttaggaaaat cattcaaata attttcaatt gttttaccta ataacatttt
    70681 ttttatttta tcttcatcct ctgaattttt agatattgca taatctttaa ttagaaattc
    70741 tagagctttt ctataaccaa ctccagcaat ttgttccaat tgctcagatt tagcttgtgt
    70801 ggcttgagta taaatatcaa caaatgtagg agaaactttt tcaatatttt ctggtaaatc
    70861 tattttaatc ggcggacggt aataatcttt aattaaaata ttttcagaat atccttcatc
    70921 ttcattaaac gtatttataa attgtaaact ataaaatttg ttgcactcat catttataca
    70981 ctgtactaat acgccaaaga ttctatcatt atcgaacgca ctatatgatg aaaccccaaa
    71041 atacacatac ggagtcatta tatttccgca atgcggacaa ctatttggca aataaattgt
    71101 ctctgtattt tgacgatcac gatacttaat attaacttct tgaagcatta aaacacctcg
    71161 catctttttt ataaatcata ccacaaaata tctgatagga gagtaaacaa atgaatgatt
    71221 ttcatgaagc ggtacttagt attgaagtag aatcaagttt ggctaaagtt tataagaaag
    71281 caattgaagc agagaatagt ccgtacagag aaaattggaa tggtaatcat gcacatgtgc
    71341 aagtggagaa tgatgattac agaactggaa tgaatacgtt agttatttct ttattgtcac
    71401 acactctacc caatctgcag gaaacgattg aatggtatga gcgaatgggc gcaaaagtaa
    71461 tccgtacaaa ttacaaagga gagaattaaa atggcaatga tcaaaattag aacatccatt
    71521 agtggaacag agtattggga ttcagaaaag aaaaggacag tagttgttcc gaaagatcaa
    71581 gaaccaaatt ttgaagtaaa agaagaaaaa ggaattttga gtgatggcaa atcatttgtt
    71641 gctgtcaatg gcgaactcat agctcatagc agtgaaattc ttgatagcga tggaaacact
    71701 gctgctaatt ttgatggaga cgaagctact aatgatcagt ccactgaaga tacggatgaa
    71761 ctggacaata tgactgcaaa agaattgcgt gcatatgcta agaaacatgg tattgatatt
    71821 cctggtgcta tccgtgcaaa aggcgatatc ataaatctta ttcgtgaagt agaatgaaat
    71881 actgtcagtt tgacggatgc acgaacaaaa tagcaaaggg tatctactgt actgaacaca
    71941 agagatcaag cagatcacgc aagaagaagc agcaagcaaa gtctgtttat catcatgaga
    72001 acaaaccatt ctatcgaacg caagcatgga aagatatgcg tcaatttatt tatgaaagag
    72061 aaggtggtca ttgtcagcgg tgtggtcagt tcatatttgg aaagagagca cacgtccatc
    72121 acattgtacc aatcaaagac aacgaactgc ttaagcttga tccaaacaat ctcatgctat
    72181 tatgttcaaa atgtcatcca attgttgaaa acgaaacgga agacaaaaaa gtttttcctt
    72241 cgtatttcaa ttgaagcccc cctattcatt ttcaaaattt tttcgcgtgg ggagataggg
    72301 tagcggggag tcacgcgcat cgttaggtca aatttttcaa aaaacaaagg ggggtgtata
    72361 caaaaatgac gactaaagcg caacgtaaag cgattattga tgaaaaagta agtgctgaaa
    72421 aagctcgtat cttagaaata atgaatttgt ctgatttgta caccatcact cttgatccat
    72481 taatcgaatc atacttggat atttttgaaa tttaccaaca caaatattta ttgtggaagg
    72541 aaaaaggatt tccggagacg caaaaattca cgaataaatc aggagctact aatcaatcaa
    72601 aacatccatt ggcacaacaa gtagaaactt gggcagataa gaagatgaaa gctctagatt
    72661 tattaggatt aacaaacaaa gcaaaaactg gtagactaat tgctggagga tcgaccgcaa
    72721 gaaaagatga agaaattaca cgcccagaag taaagccagt agatgaacta gcagcgcaca
    72781 gaaataaatg gcgtaagaag gcaggtgctg aaaaatgatt gaacctggtg taaattatgc
    72841 tgatttattt gcaaaagaag taagaaagaa acctaagaag tatcctaaga ccgttcgttt
    72901 agcaatagat cgctggtatc agtggaaaaa aagaaaagat atttggtttg atgtagatcg
    72961 cgcgaatgaa atgatggatt gggtagaatc atttattgtt cacacaaaag gagaaatggt
    73021 gggaaaaccg tttcttttag aaccctggga aaaatttatt tattcttgga tttatggttg
    73081 ggttaaagaa aatgaaaaag gccaaattgt acgcgttact cgtgaggctt atgtccagat
    73141 tccaaaaaag aatggtaaaa cattgattgc tgtcggttca ttaggatatg caatgtacgg
    73201 agaaggggcg ttatcagttg attgctatgc ttgcgcatct gattttgctc aagcgcaata
    73261 tgctgccaaa ccttttgcag ttacaatctt aaacaatcca atcctacttg aaggaactaa
    73321 aatatttagg gggccaaagg gaactgtttc tagtattact tatgactata ttcatgaaga
    73381 tatggcttac tcaaataaat ttattgttca aaccaagaat attgataata tcgagggatc
    73441 caatccatat tttgtattga acgatgaatt gcataaacag gagaaaatgg aacagtatga
    73501 caattttaag tctgctcaga tatctttacc acagccattg atgtttaata tctcaactgc
    73561 tgggaaaggt tcgtcgtctg ttggaatgcg tgtatatcgc gaagcaaaag aagtgttgaa
    73621 acgtgatgat aatgattcaa actttgttct aatctatgag ccaaataaaa attatgattg
    73681 gacggataga aaagtctggg aaatgtgcaa tcctaactgg ggaatatcag tcgatttatc
    73741 tgctttagaa tcggcattta aaacagcgca acggtcagct cattccaaag ctgaatttct
    73801 aacgaaacac ttggatgtat ttgtgaacgg cgcggataat ttctttgaac aggatcaagt
    73861 agagccatgt ttagttacca cacaagaact tggtgattta agtggcgaac catgttatat
    73921 cggtttagat ttatcacgta cacgagattt gacctgtgta tctttaaact tcccaacatg
    73981 ggatgaagat ggtaaagcgg ttcttaaagt aaagcaactt tattttattc cgaatgaaga
    74041 tttagagttt cgagaaaaag aagataatgt tccttacagt gatttggctg aacaaggttt
    74101 cgttgaattt tgcgacggaa aaatgattga tcaagatcag attttgcagt acatagagga
    74161 ctgcatgaat ttatatgata ttcagcaagt gaattatgat ccagcgatga gtgacaaact
    74221 tgttgagaaa ttagaaaact taggattgga atgcgttgaa gttgctcaat atcctaaagt
    74281 attgaatgct ccttttgacg atgtcgaacg gttgttttat gagaaacgaa ttcaatttga
    74341 taatccatta ttcctttatt gcactttgaa cgttgtagca attactaaca tcaatggaca
    74401 aaaagcgcca agtaaacgtc aatcaaagaa aaagattgat gggttcgtgg cgtttttgtg
    74461 tggtcataag gaaacgatga atcaaatgac agatattgat tcagatgagt tagatgatta
    74521 cctaagttcc atctatagat aaatagaaag gcggtgaaaa aaattgaaat tacgtgatcg
    74581 gttatcgaat gcagtctatt cttttatgga aaaacgtgga tatatcgagg atatttttgg
    74641 acactacaca cgttatggtc aaagatatgt gacggattca tctatcatgg aatcttctga
    74701 tgtttatgaa ttagttcaag acatatctaa tcaggtggca ttggccacac caattgttat
    74761 tggtcccgac ggcaacgaag tcaaagatca tcacttacta aatattttga agagtcccaa
    74821 tgattatttg acaggattcg aatttaccaa attggaaaca aatactttat tgatcaatgg
    74881 tgagacattc ccattaacgg atagggatca gcttcatttg gcgtacggtg taacaactaa
    74941 aatcaatgaa cgacttcaag aagaatttga aatgaatggt caaaaaatac ctggtcaaat
    75001 gattcgacac attaagaaca tcggaactga ttcattaaaa ggtgctggaa taattgatct
    75061 tgcaagaaac actctagaag gcgttctgag cgctgaaaaa gttttgacgg acaaatatac
    75121 taaaggcggt ttacttgcgt tcatgcttaa actagacgcc cacatcaatc caaataatag
    75181 cgcccaaaca aaaattgtca aagctatatt ggatcaactg gaaggaacgc aaaatgagag
    75241 tgatcattct gttaagatga ttcctttggg aaaaggatat tccatcgaga cattaaaaag
    75301 tcctgttgat gacgcggcaa ttttgaatta tttaggtgtt tacaaaaaag acttaggaaa
    75361 atttctagga atcaatgttg atacgtatca atcgctgatg aagacagata ttgaaaaagc
    75421 gatgatgtat ctgcacaaca aagcaatcaa accaatattg aaaaacaaga gcgaacatta
    75481 caccgctctt ttttttatgc ctaattctgg ctatagagtg gaatggaaaa ttaatatttt
    75541 ggattttgtt ccttactcaa caaaaacaaa tattggctac aacatcgttc gtaccgggat
    75601 tacaagtcca gataacgtgg cagaaatgct tggttttcct aaacagaata ctccagaaac
    75661 acaagctatc tatatttcaa atgacttatc taggattggc cagaaaaatg caacagatga
    75721 ttccttacca acgaatgatc aagacttgaa aggaggtgat ggaaatgaag aagaaggaaa
    75781 ttcgcacgat tgacatcacc aatctttcaa cacgttccga tgaagaaact catacgagga
    75841 ccattagcgg ctacgctgct gtattcaaca gtcaaacact tttatgggat gacttaagcg
    75901 aagtgattgt tcctggtgca ttctcaaagg caattagtaa ttcggatgtt cgttgtttgt
    75961 tcaatcacga ttggtccaat gtgctaggac gtactaaaag cggaaccctt cgccttgaag
    76021 aagatgaacg tggtttgaaa ttcgaagttg atttaccgga cacaacggta gcaagggact
    76081 tagttaaatc tatggaacga ggagacatca accaatgtag ttttggtttt gtgccgactg
    76141 aagaaacgtg ggactacaat tctgaaccaa tgcttcgaac aatccatgaa gtggaattat
    76201 acgaggtttc tattgtgcct ttgccagcat acgaagatac agaagctgca ttaagaagtc
    76261 gtgatgaatt agaaaaaaac gtcgaagaaa gaaaaaaatt aatcaaaaaa attaatcaag
    76321 cgctagaagc gtaggaggaa aaatacatgg ataaagaatt attgaaaaaa atgaaggcac
    76381 gtcgtgagca acgattgact gaattacgtg aaaaagttga atcaggagaa ttacgcgaag
    76441 cagatttaga agccgtgaaa gaagaaattg acagtgttat tgatgaattg aacggaatta
    76501 aagacgaatt aggcgcagat tctggaactg atgaaacaga cgacaataca gatgatcaat
    76561 cgaatagtac ggattcagac gaaagccgtt ctggtgaaga caacgatcaa gaagaagatt
    76621 cagacagtga agatagttca gaaaatcgtt ctggaatgat tactcaacag caacgagatg
    76681 gattacttgg atcaattaag aacggattgg aggcacgtgc aaaaatgacc aagaaacaaa
    76741 aagatcaaca actacgaaaa gcatttgcta attttgtagc tggaaatatt tctgaagcag
    76801 aagctcgagc tttagggatt gaagctggca acggttcagt tactgtccca gaagtaattg
    76861 catctgaagt tattacttat gctcaagaag aaaatttact tcgtaaatac ggaacagtgg
    76921 tgcgaacatc aggagatgtc aaatatccaa ttcttgtgaa gaaagcagat gcgaatgtaa
    76981 acaagaaaga gcgttcaact gatattgctg aaacagctat tcagtttgat gaaattttgc
    77041 ttaatcctgc cgaattcgat gctttggcaa cagtaactaa aaaattatta aaaatgtctg
    77101 gtgttccagt tgaagatatt gttgtggaag aattgaaaaa agcttatgtg cgtaaagaaa
    77161 tcaattatat gttcaatggt gatgacgctg gaaatgaaaa tcctggtgca ttagccaaaa
    77221 aggctgtagc atttaaaaaa cctttagatc taactgcttc aggtgctggg caaaaattat
    77281 atgatgcatt aatcgaattt aaaaatacac cagtgacaga agtgatgaaa aagggacgct
    77341 ttattattaa tcgagctgct ttgactgcca ttgaaaaaat gaaaacagat gatggatttc
    77401 ctttgttgcg gccattcaca caagcagaag gtggaattgg ttaccaatta gttggctatc
    77461 ctgtggattg gacagatgca gcagataaaa agggtgaacc agacacgcca gttttatatt
    77521 ttggcgattt ttctgcattt aaaattcaag aagttattgg tgccttggaa attcaaaaac
    77581 ttgttgaaaa attctctggt aaaaatcaaa ttggattcca aatttacaac ttgctagatg
    77641 gtcaattggt ttattctcca tttgaaccgg cagtatatcg ctacgaaatt acaaaaccag
    77701 ttggtggtta agatggaaga gcaaactaaa gaattgtctt tagaggaaaa attcaaatca
    77761 catattcatt ttgaagaggg catggatgat tctttgctct ctttttattt aaatatggca
    77821 aaagattatg tcaaaacagc aactggtggc caacaagaat atcttatttt gatggttgcc
    77881 ggcattgcct atgaatatag agtttcagag gatgaactcg acaaagctat gaatgccatg
    77941 acgccattta tcgtgcaagg agcgattcaa aatgccgaag agacagacca ataatctcag
    78001 atggaaagcc gaattgctag acatcaaaac aggaacagac ggaaacgatc gtccaactac
    78061 aatttacgaa tttaagcgtc taatattcta tgaagaactc ggtgtgactt ctcaagaaaa
    78121 atatttatca cagcaagcca agacagacgt tgtcagacga attaaagtca gatgggataa
    78181 atccatcaca gagaaattaa gtgcgctcaa aattgattct gtaacgtata acattactcg
    78241 catttatacg aatcccgatg caagagaaat ggagttgagt ttagcttatg tcgattagct
    78301 ttgatgaatt gaaaacagcg ctgaaatcaa caaagttagc agtgttcaga gacaaagcca
    78361 gattagggac gatgtatcca tacattgtgt actcaaatgt gagtaacagc aaaaaaatgg
    78421 catccggtaa agtctataaa aaattacctt attaccaagt ctcttttttt acacttggaa
    78481 cagaacagga tttagttgtt attgaacaag cgctgcaaaa tgctggcatt ccatattcag
    78541 attttacagg tatacaaggt gatgagaacg acgataccgt aaccaactat tacacatatg
    78601 tgaggtgtgt ggaaaatgcc aagtaataag aatggttttt ctgaaatatc ggattattta
    78661 ggaaaccttt caaaagttga tccgaaaaaa ttatcgttgg aatctttaga agaagcagct
    78721 aacttttatc taaagcagtt gcttcctaat attcctaagt cgctcttaaa aaagaaacat
    78781 atgcgcgatc aaataaaagt agtagttgaa aacgatcaag tgaaagttca atttgaagag
    78841 acggcctttt actggcgctt tgccgaaaat ggcacaacaa atcaacgtgc ccaacatttt
    78901 gcaagtggta cgtatgaaca aaacaaagaa aaaattgaag aaattatgac tagaaaaata
    78961 cttgatttat gggaagggtg attttaattg ggaaaacaag atacttttta ttttgaagga
    79021 ttggacgaca ttttaattgc gatgatggca acgccagatt ctgttggaac tgcaccgact
    79081 tatagtgaag ttttacgatt gccaattgcc acaaaaatcg gtgtcaaagg gaatggaaca
    79141 gcattagaaa aatgggcatc cagcaaaatg tttcgtcgtg tgtcgcgaga aacaaaacat
    79201 gaacttgcgt tggatcacgt gggtattccg atagaagtga tggatgaaat caaaggatta
    79261 gttgctaaaa gcggagtaac gtttagcaaa aataccgcac gagaatttcc gtacttcgcc
    79321 tttggattta ttggaaatat tgaaaatggc ggtaaaaaag cagtttggta tcctaataca
    79381 caactatcca atgtgattga cgaagagtat gccactgcag aggaagaaac aaaaattgac
    79441 gatgtaactg caaatctggt ttccatcgga ctgaaataca ataatgtgat gtatgcaagt
    79501 tttgattcaa atagagacgg agcttctcta gaattattta ataaattcat tgctcaacct
    79561 gtatacgatg aagaacagtg gaaaacattg gctaaagttg gaggtgcggg ttaatggctc
    79621 ggttatctga ttatggaatt cacgttgaag acttaaaaaa ttctgctgtt gtaattattc
    79681 aaggcgcaga attccctatt tcatttacta tgcaaacgat ggaatttata gcagatgtgt
    79741 atggtggaga ttattcgcaa tttgaatctg atatgaacgc catgctatct aaaaaagaag
    79801 gacaaatttc ttctgctaac ttatcgccta gtgatctaaa aatcatgcgt gccttgattt
    79861 atgccatgct gcgtactggt ggtttagagg aagatccaga aactattttc aaatttttgg
    79921 gaatgagtgg agaggtgttg tctgcttata gtacctgtat ggaaattttt gctagccaga
    79981 catttcaggt ggaagaccta aaaaaatcca agaagccaca agactttcaa aaagcgcaag
    80041 caaaaagaaa gaaaaacaaa aagaatcgga agagatagga actccttgga gtttttatat
    80101 ttacgttgct ctcactctat tgaattggag tgagagtttc tttttaaagt ctacacctaa
    80161 cttgtggctc aaatcttatt tacagtggtt acaacaaaac accgattttg aaccacctca
    80221 atctgtaact atggataaat cgccttggtg gtagaaagga gcgctaagat aaatggctgg
    80281 taaagaatct gatgtcgttc ttaattttaa aacgaatggc gaagtcagtt attcgaaaac
    80341 aatcaaagaa atcaacaaag aaatgaactt agccgctgcc gagtacaaaa accaagtgtc
    80401 tgcgatggac aaggatgcaa ctcaaacaga aaaattgcga gcggctaaac aaaaattaga
    80461 aaaacaatta ggattggctg aacaacgatc tcaaatgctg agagaggaat atgaaaaatc
    80521 tgtcaaagaa accggtgaat attctgctga atcagaaaaa ctttataaac aattactcaa
    80581 ttctgaaacc ggagaaaata aacttcgtac agcattagaa cagacgaacg atgcacttaa
    80641 agaacaaggt gacgtttctg ttgatacagc aaaaaaactc cagaaaatcg aagaaacagg
    80701 tgagaaagta aaaggcgttg gtgaaaaaat gtctgttgga gtaaccgcgc ctattgtagc
    80761 ggcaggagca gcaggacttg cagcatttgg tgaagttgac gaggcacttg ataccatcat
    80821 tacaaaaacc ggagcaacag gtgatcaagc tgatagactt tcacagtctt tcaaaaacgt
    80881 tggttcaaat actcatttac ctttacaaac ggttggggaa gctattggtg aggtaaatac
    80941 acaatttgga ttcatggata aaaaactgga agattcaacc aattatctcc tacagtacgc
    81001 tgaaatcaat gatacagatg tttcgcaatc agcaatatct gctcgacaag ctattgatgc
    81061 ttatggacta gaatatgatg atttgaattc tgtccttgat gtaacaacga aaacatcgca
    81121 gaatactggt caatctgtag acgacttgat gcaaaaagca attgatggcg caccacaaat
    81181 taaacaatta gggttgagct ttggtgaagg ggtcacttta cttggacaat ttgagcaatc
    81241 tggtgttgat tcaagcgcag ctttaagtag tttatctaaa gcaacagtgg cttatgcgaa
    81301 agacggaaaa tctttaagtc aaggactaga agaactacaa gacaaggtaa aaaatgcagg
    81361 ttctgaaaca gaagccatca atgcagcagc agaagtattc gggactaaag gcggtcctag
    81421 aatggccgat gcaattcgta gaggtacttt gaacctggaa gatttagcaa aaactgctgg
    81481 agaaagtggg ggagctgtag gagacacatt cgatgctact ctcgacccaa ttgatcaagc
    81541 cgatcaagct atgaacaatg caaaattagc aatggctgac gtaggtgaag cagtccaagt
    81601 aagccttttg cctttttttg aaaaagcaac ttccttatta caggaattct ctaaatggtg
    81661 ggggtctcta gatcaagata caaagaattg gatcataaca attgctggta tagcggcagc
    81721 agttggacca gtactaatcg ttcttggttc acttatggga tctgttacaa aaatcgttgg
    81781 ggaagttaaa agttttatag gagtttggca aggacttgct ggtttatttg gaatgtcggg
    81841 aggctggttt gcattagcag ttatagctat tggcgcatta gttactggac taatttgggc
    81901 atataataac gttaaatggt ttcatgatgg agtgaattct ttcttcaaag gtgtttcaga
    81961 tgtagctgtt gaaatattta attttttaag tggttatttt ggtggatttt tcgatggtgt
    82021 tatagcaaat ttcaataatt tttataatgc tggaaaacga attttcagtg gttttctaga
    82081 ttttatcact ggagtattta cagggaattg gtcaaaagca tggcaaggtc tagttgatat
    82141 ttttggaggt attttcgatg gtattgttgc tgtagggaaa gctcctatta atgccatgat
    82201 tggattgatc aatggattta ttggtggatt gaataatata aagataccaa aatgggttcc
    82261 tggtgtaggt ggaaaatcat tttctatttc aaaactgcct tatttagcac aaggcggtca
    82321 tctaatcaat ggacaagcga ttgttggtga agctggacct gagttactga ctgccaagaa
    82381 tggtaaaacc acagttactc cattatcaga cgaagaaaaa cgcaaaggga tcagtggaag
    82441 agtttctgga ggtagcattg aacagcatat acacattggc aaagtcgatg caaacaatcc
    82501 atctgagtta gatcgtatga atcgtaaatt tgctaaagca aacaaacagg ctattcgtga
    82561 tttgggaggt gttcctattt gagtcgacaa tttatgaatc cagatgaacc aaattttatt
    82621 tggaaaaatc ggaatgcagt aattgatatg aattgcatca ttgaggcaga gcttccagat
    82681 attatgccga acaagcgata cgaaacttac acgattcagg gccgaagcgg agaattgacg
    82741 gagacgtttg atgactatga accttttgat ttggaaatag aagggatcac tattccacat
    82801 tcgaaactga gagaagtcaa acgatggctc actggtaaaa gccaattaat cacacataat
    82861 gatccagaca agtatctaga ggctatctgc agcatggata aagaagtccc tttcgaaaac
    82921 gagtggggct tcttttatac attcgatgtt acttttcgtt gtcagccact caaaagaaaa
    82981 atcggtgaag cacctaaaat ttttcattct agtgttatgg atatttttga tcatggtgac
    83041 gaaattgcac atccctatct ggaaatagaa tcgaacggag gagatataac gatcgctgtc
    83101 ggtgataaaa gcctaacaat acttaatacg ttagctgcaa caatcgtggt tgatactcag
    83161 cttggaaaag caatacaaga aggtttgaat ttatttacgc gtggtgattg gccagtattg
    83221 cagcctgaat ggaatcaggt aaaaatatcc ggaaaattta aagaagtgcg gttttggaat
    83281 aggagtgtgt atctgtgacg caagaattta tttatgctta taaaaaaatg ccagatgatt
    83341 tgagcgtgaa cggagcgtcg ttagttgatt gggaagattt gccagaaatc aatcgtgtgc
    83401 tgaatggcca atatcgtttt tatggtaact attcaagaag cggacagtat cgctcttatt
    83461 taaaaaaagg aaattttata aaagcgaagg taccagatgg atcatggcaa tattttgaaa
    83521 tttataatgt caaaaagaat ttgacctccg tttctgtaac agctcggcat attggtttta
    83581 tggccaataa gaactttatt gtcaagtcgt ttacggataa cggcaatggg tctcagatca
    83641 tgaccaatct taaaaacagt ttggcatttg atcaaaaatt taactatctt tcgaatgtag
    83701 ggacaacgca ccaatttaca gcaagacaag tcgcgccagt tgaagcaatc attggttcaa
    83761 ataacggtaa tcaaaatttg actggcgtga ctagcgcgga acttgatatg gataactatg
    83821 atttgaaact ggtaaaacag attggatcag ataatggttt tcggattgat tttggcatca
    83881 atttagaagc aatcgaagaa gaaattgatg aagaatcaat tgtcaatagt ttgtatttgg
    83941 ttggcggtgt tcctgataac gattatgatg aagacaaaga acctatcgaa tatggttatt
    84001 tagaaattga tggagtaacc aacgagaatc gacgtattgc caaacgtgaa aacggagatt
    84061 gtaaaacagt tgatgaattg atcaaatggg gcaaaacctt atttgacaat gatcgtatcc
    84121 atgagccaaa agctactcat acagtcagta tggtggcgtt ggaacacaca ctcgaatacg
    84181 gtgacatgta tcaagagcta gcgtctttac actttggtga tgtcgctcat gttagggcga
    84241 aagagctaga tatcgagata aaagagcgta tggtcgaata cacttatttc ccaacgcttg
    84301 ggaaatataa ggatattgtt ttaggtaatg atttatcact gtacacttcg gcagtaaata
    84361 ctcaagcaca agaattgaaa aagaaaatcg acaatcgaac agaaacgtta gttcaaaatg
    84421 tgttgaatgc gacggcatgg atcactggta attctggtgg gcatgtcgtt tttcgtccag
    84481 aaaaagctcc atcagagatt cttatcatgg atactccaaa tgtggcgaat gcaaagcgag
    84541 tgtggcgttg gaatttaaat ggcttaggtt attcagacaa cggagtaaat ggcccgttcg
    84601 gtattgctat cacatcaaaa ggagaaattg ttgctgactt catcaaagta ggaacaataa
    84661 atgcagaagt attcgaaact tcctttaatg cttatggtga tgtgttaaaa cttgtaaaag
    84721 gcacgcttca aatttggaat gaaaacaaaa aaatcatgga gctaaccaaa aaaggtatgg
    84781 aattctggaa tagaaaagaa tccattggaa cgatcggaac aacagattca gcaggaaatc
    84841 catttccaaa tgctgtaaca cctacacctc ttgaggaaaa ttctttggta atacgtacaa
    84901 atggcgatgg aaaatacatt ttaatttctc caactgcaga aaaaggattt gtgttattag
    84961 gaaacggaaa agcatattat ttcggtgatt tagatattca gggaaaactt actgttagag
    85021 gtaaagaagt gataccagga caaaatggcg gtccatctgg cggaggagaa acacctggtg
    85081 ggtatcctga tgaattaaaa acagatgcag aaaagagagc ttggagaat
//
LOCUS       DADLIO010000004        80168 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.004, whole genome shotgun sequence.
ACCESSION   DADLIO010000004 DADLIO010000000
VERSION     DADLIO010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 80168)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80168)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80168
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.004"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(207..947)
                     /locus_tag="JOX41_000357"
     CDS             complement(207..947)
                     /locus_tag="JOX41_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448127.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(1077..2024)
                     /locus_tag="JOX41_000358"
     CDS             complement(1077..2024)
                     /locus_tag="JOX41_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAY6448128.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            complement(2153..2917)
                     /locus_tag="JOX41_000359"
     CDS             complement(2153..2917)
                     /locus_tag="JOX41_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAY6448129.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            complement(2921..3310)
                     /locus_tag="JOX41_000360"
     CDS             complement(2921..3310)
                     /locus_tag="JOX41_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448130.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            3445..3987
                     /locus_tag="JOX41_000361"
     CDS             3445..3987
                     /locus_tag="JOX41_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HAY6448131.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            4135..4767
                     /locus_tag="JOX41_000362"
     CDS             4135..4767
                     /locus_tag="JOX41_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448132.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(4901..5026)
                     /locus_tag="JOX41_000363"
     CDS             complement(4901..5026)
                     /locus_tag="JOX41_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAY6448133.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(5160..6053)
                     /locus_tag="JOX41_000364"
     CDS             complement(5160..6053)
                     /locus_tag="JOX41_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HAY6448134.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEIAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(6235..7161)
                     /locus_tag="JOX41_000365"
     CDS             complement(6235..7161)
                     /locus_tag="JOX41_000365"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HAY6448135.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(7246..8007)
                     /gene="pflA"
                     /locus_tag="JOX41_000366"
     CDS             complement(7246..8007)
                     /gene="pflA"
                     /locus_tag="JOX41_000366"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HAY6448136.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(8251..10482)
                     /gene="pflB"
                     /locus_tag="JOX41_000367"
     CDS             complement(8251..10482)
                     /gene="pflB"
                     /locus_tag="JOX41_000367"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HAY6448137.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(10759..13209)
                     /gene="parC"
                     /locus_tag="JOX41_000368"
     CDS             complement(10759..13209)
                     /gene="parC"
                     /locus_tag="JOX41_000368"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HAY6448138.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(13221..15266)
                     /gene="parE"
                     /locus_tag="JOX41_000369"
     CDS             complement(13221..15266)
                     /gene="parE"
                     /locus_tag="JOX41_000369"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HAY6448139.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(15432..15866)
                     /locus_tag="JOX41_000370"
     CDS             complement(15432..15866)
                     /locus_tag="JOX41_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HAY6448140.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            15993..16631
                     /gene="plsY"
                     /locus_tag="JOX41_000371"
     CDS             15993..16631
                     /gene="plsY"
                     /locus_tag="JOX41_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HAY6448141.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(16763..17638)
                     /locus_tag="JOX41_000372"
     CDS             complement(16763..17638)
                     /locus_tag="JOX41_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HAY6448142.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(17720..18511)
                     /gene="codY"
                     /locus_tag="JOX41_000373"
     CDS             complement(17720..18511)
                     /gene="codY"
                     /locus_tag="JOX41_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HAY6448143.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(18529..19929)
                     /gene="hslU"
                     /locus_tag="JOX41_000374"
     CDS             complement(18529..19929)
                     /gene="hslU"
                     /locus_tag="JOX41_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HAY6448144.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(19943..20491)
                     /gene="hslV"
                     /locus_tag="JOX41_000375"
     CDS             complement(19943..20491)
                     /gene="hslV"
                     /locus_tag="JOX41_000375"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HAY6448145.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(20528..21433)
                     /gene="xerC"
                     /locus_tag="JOX41_000376"
     CDS             complement(20528..21433)
                     /gene="xerC"
                     /locus_tag="JOX41_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HAY6448146.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(21631..23007)
                     /gene="trmFO"
                     /locus_tag="JOX41_000377"
     CDS             complement(21631..23007)
                     /gene="trmFO"
                     /locus_tag="JOX41_000377"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HAY6448147.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(22976..25054)
                     /gene="topA"
                     /locus_tag="JOX41_000378"
     CDS             complement(22976..25054)
                     /gene="topA"
                     /locus_tag="JOX41_000378"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HAY6448148.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(25176..26033)
                     /gene="dprA"
                     /locus_tag="JOX41_000379"
     CDS             complement(25176..26033)
                     /gene="dprA"
                     /locus_tag="JOX41_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HAY6448149.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(26089..26856)
                     /locus_tag="JOX41_000380"
     CDS             complement(26089..26856)
                     /locus_tag="JOX41_000380"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HAY6448150.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(26849..27709)
                     /gene="ylqF"
                     /locus_tag="JOX41_000381"
     CDS             complement(26849..27709)
                     /gene="ylqF"
                     /locus_tag="JOX41_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HAY6448151.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            27969..28367
                     /locus_tag="JOX41_000382"
     CDS             27969..28367
                     /locus_tag="JOX41_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAY6448152.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            28604..29146
                     /locus_tag="JOX41_000383"
     CDS             28604..29146
                     /locus_tag="JOX41_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAY6448153.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(29229..29780)
                     /gene="lepB"
                     /locus_tag="JOX41_000384"
     CDS             complement(29229..29780)
                     /gene="lepB"
                     /locus_tag="JOX41_000384"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAY6448154.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(29932..30159)
                     /locus_tag="JOX41_000385"
     CDS             complement(29932..30159)
                     /locus_tag="JOX41_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HAY6448155.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(30156..30674)
                     /gene="msrA"
                     /locus_tag="JOX41_000386"
     CDS             complement(30156..30674)
                     /gene="msrA"
                     /locus_tag="JOX41_000386"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAY6448156.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(30694..31407)
                     /locus_tag="JOX41_000387"
     CDS             complement(30694..31407)
                     /locus_tag="JOX41_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HAY6448157.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(31410..32306)
                     /locus_tag="JOX41_000388"
     CDS             complement(31410..32306)
                     /locus_tag="JOX41_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAY6448158.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(32464..33306)
                     /locus_tag="JOX41_000389"
     CDS             complement(32464..33306)
                     /locus_tag="JOX41_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAY6448159.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            33438..34091
                     /locus_tag="JOX41_000390"
     CDS             33438..34091
                     /locus_tag="JOX41_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HAY6448160.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(34154..34681)
                     /locus_tag="JOX41_000391"
     CDS             complement(34154..34681)
                     /locus_tag="JOX41_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAY6448161.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(34701..35648)
                     /locus_tag="JOX41_000392"
     CDS             complement(34701..35648)
                     /locus_tag="JOX41_000392"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAY6448162.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(35660..37546)
                     /locus_tag="JOX41_000393"
     CDS             complement(35660..37546)
                     /locus_tag="JOX41_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAY6448163.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            complement(37706..39784)
                     /locus_tag="JOX41_000394"
     CDS             complement(37706..39784)
                     /locus_tag="JOX41_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAY6448164.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            complement(39797..40072)
                     /locus_tag="JOX41_000395"
     CDS             complement(39797..40072)
                     /locus_tag="JOX41_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448165.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(40434..40889)
                     /locus_tag="JOX41_000396"
     CDS             complement(40434..40889)
                     /locus_tag="JOX41_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448166.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(41043..42251)
                     /locus_tag="JOX41_000397"
     CDS             complement(41043..42251)
                     /locus_tag="JOX41_000397"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HAY6448167.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(42363..42695)
                     /locus_tag="JOX41_000398"
     CDS             complement(42363..42695)
                     /locus_tag="JOX41_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAY6448168.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            42843..43718
                     /locus_tag="JOX41_000399"
     CDS             42843..43718
                     /locus_tag="JOX41_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAY6448169.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(43800..44381)
                     /locus_tag="JOX41_000400"
     CDS             complement(43800..44381)
                     /locus_tag="JOX41_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IDEAL domain-containing protein"
                     /protein_id="HAY6448170.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(44387..45646)
                     /locus_tag="JOX41_000401"
     CDS             complement(44387..45646)
                     /locus_tag="JOX41_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAY6448171.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(45648..46694)
                     /locus_tag="JOX41_000402"
     CDS             complement(45648..46694)
                     /locus_tag="JOX41_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448172.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(46929..47204)
                     /locus_tag="JOX41_000403"
     CDS             complement(46929..47204)
                     /locus_tag="JOX41_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008214712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HAY6448173.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(47447..48757)
                     /locus_tag="JOX41_000404"
     CDS             complement(47447..48757)
                     /locus_tag="JOX41_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HAY6448174.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(48939..50168)
                     /gene="rpsA"
                     /locus_tag="JOX41_000405"
     CDS             complement(48939..50168)
                     /gene="rpsA"
                     /locus_tag="JOX41_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HAY6448175.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(50303..50983)
                     /locus_tag="JOX41_000406"
     CDS             complement(50303..50983)
                     /locus_tag="JOX41_000406"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HAY6448176.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(51032..51667)
                     /locus_tag="JOX41_000407"
     CDS             complement(51032..51667)
                     /locus_tag="JOX41_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAY6448177.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(51733..53136)
                     /locus_tag="JOX41_000408"
     CDS             complement(51733..53136)
                     /locus_tag="JOX41_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HAY6448178.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWGTILLNLFKKNMEH"
     gene            complement(53123..54154)
                     /locus_tag="JOX41_000409"
     CDS             complement(53123..54154)
                     /locus_tag="JOX41_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448179.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            54185..54406
                     /locus_tag="JOX41_000410"
     CDS             54185..54406
                     /locus_tag="JOX41_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HAY6448180.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(54571..55308)
                     /locus_tag="JOX41_000411"
     CDS             complement(54571..55308)
                     /locus_tag="JOX41_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HAY6448181.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(55461..56801)
                     /locus_tag="JOX41_000412"
     CDS             complement(55461..56801)
                     /locus_tag="JOX41_000412"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HAY6448182.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(57038..58561)
                     /locus_tag="JOX41_000413"
     CDS             complement(57038..58561)
                     /locus_tag="JOX41_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HAY6448183.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(58939..59550)
                     /locus_tag="JOX41_000414"
     CDS             complement(58939..59550)
                     /locus_tag="JOX41_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAY6448184.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(59673..59798)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(59880..60596)
                     /locus_tag="JOX41_000415"
     CDS             complement(59880..60596)
                     /locus_tag="JOX41_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAY6448185.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(60602..61171)
                     /gene="scpB"
                     /locus_tag="JOX41_000416"
     CDS             complement(60602..61171)
                     /gene="scpB"
                     /locus_tag="JOX41_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HAY6448186.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(61155..61952)
                     /locus_tag="JOX41_000417"
     CDS             complement(61155..61952)
                     /locus_tag="JOX41_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HAY6448187.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(61922..62293)
                     /locus_tag="JOX41_000418"
     CDS             complement(61922..62293)
                     /locus_tag="JOX41_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAY6448188.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(62312..63199)
                     /gene="xerD"
                     /locus_tag="JOX41_000419"
     CDS             complement(62312..63199)
                     /gene="xerD"
                     /locus_tag="JOX41_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HAY6448189.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(63295..63768)
                     /locus_tag="JOX41_000420"
     CDS             complement(63295..63768)
                     /locus_tag="JOX41_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAY6448190.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(63873..64736)
                     /locus_tag="JOX41_000421"
     CDS             complement(63873..64736)
                     /locus_tag="JOX41_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAY6448191.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(64932..67031)
                     /locus_tag="JOX41_000422"
     CDS             complement(64932..67031)
                     /locus_tag="JOX41_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HAY6448192.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            complement(67251..68360)
                     /gene="rpoD"
                     /locus_tag="JOX41_000423"
     CDS             complement(67251..68360)
                     /gene="rpoD"
                     /locus_tag="JOX41_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HAY6448193.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(68384..70225)
                     /locus_tag="JOX41_000424"
     CDS             complement(68384..70225)
                     /locus_tag="JOX41_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HAY6448194.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVRNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(70407..72800)
                     /locus_tag="JOX41_000425"
     CDS             complement(70407..72800)
                     /locus_tag="JOX41_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAY6448195.1"
                     /translation="MFLILEHARLKHVIIFESWRKMEKKKMNGLTQQEVVQKMASGQQ
                     NDYQEDASKSTKQIFSDNILTLFNFLNFGIGICLLFVGAYSNMAYLAIIVVNIVIGIY
                     QEIHARNLVRKLSIVSQSEVLVIRDGKEQSISTKELVLGDLVKIGAGEQIPADLQVIS
                     GRAEANEALLTGESDLIVKETGAELLSGSFLTSGSVMAEVIRVGADNYAVRLTSEAKT
                     HKAIRSELVDSIRKVSKFTSFVIIPLGIILFLEALFIRDASIKISVIASAAALLGMLP
                     KGLVLLISIALTTGVTKLAKKRILVQDMYSIETLAHVDTLCLDKTGTITEGKMSIQRV
                     EALHPLYEKAIPEIMGTYLAESSDNNITMRAMRDYFELSNRYDVTNKVAFSSDRKWGA
                     MEFPELGVVYVGAPERLVEEDRLPDSLKTAQANGYRVLMLGIAPNQQLNEEKPAFVEP
                     VALFEIDDPIRKNAQETLAYLHEEGVDLKVISGDNPFTVSNIARRAGLPNYDAYVDLS
                     QITEEMEVREAAHRYTVFGRVSPQQKKLLVNELKESGRTVAMTGDGVNDVLALREADC
                     SIAMAEGDGATRQIANLVLLDSDFTTLPEVLFEGRRVVNNVTKVSGIFFIKTIYSFIL
                     SIICAVTAIGFPFIPIQITLIDLAIEGYPSFFLSFEQDKRKITYRYLPTALINALPNA
                     LLVVVNIIAVYLLGKTFAWGNAETTTLMYYLLIGISCMAVVKACYPFNPLRIFLAVTT
                     IVGIYVAAMLFHGILEVNLGLGESVGYFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(72907..73767)
                     /locus_tag="JOX41_000426"
     CDS             complement(72907..73767)
                     /locus_tag="JOX41_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HAY6448196.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(73826..74347)
                     /locus_tag="JOX41_000427"
     CDS             complement(73826..74347)
                     /locus_tag="JOX41_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HAY6448197.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            74667..75386
                     /locus_tag="JOX41_000428"
     CDS             74667..75386
                     /locus_tag="JOX41_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAY6448198.1"
                     /translation="MKKEKKYAKMPDGSEIYYEKSGQGFPLFLLHGNDGSGRFFSEQV
                     PVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEKIDQADFLGFSDGAN
                     LALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVWLLSLFRPSLRKNLL
                     VIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKTIPKASFVLVKEQGH
                     ELARKDPERFNREVLQFLSET"
     gene            75412..78003
                     /gene="mprF"
                     /locus_tag="JOX41_000429"
     CDS             75412..78003
                     /gene="mprF"
                     /locus_tag="JOX41_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HAY6448199.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(78191..79378)
                     /gene="tuf"
                     /locus_tag="JOX41_000430"
     CDS             complement(78191..79378)
                     /gene="tuf"
                     /locus_tag="JOX41_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAY6448200.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            79746..80102
                     /locus_tag="JOX41_000431"
     CDS             79746..80102
                     /locus_tag="JOX41_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAY6448201.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
BASE COUNT        21991 a        16850 c        13751 g        27576 t
ORIGIN      
        1 aaaaaaataa actatttttg caaacgatct gcgaaaatag tttgtttttt tattttgcca
       61 ttattttctt acttattggg agaaaaaatt cgcttaaact caaaaaaatt tgaggatacg
      121 atataaactt tcggatagag tataaaataa ggaaacgccg cagcgtttcc tttccaactg
      181 tagccgaata taaatttgta tatcacttat ttaaaatagc tattttctcc caaagagttt
      241 ccttgatcat cgatcaatcc ttgtaatgag cgttctaaga taccatggct ttttttcgat
      301 tttttttctt ctgactgctt tgtttcctct aacgtttttg ttcgattgaa tgttcgtaca
      361 gacggctcac catttctttt ttcttgatac ggcgtcggtt ctgtatcgaa caacagataa
      421 gagtcatccg tttttttcat cgattcgatt aaatgatcct cagaaatttt gctttctcta
      481 gggtctggga taatcgatgc gggtacatat ttaggaacaa aataagaacg ctcccgcacc
      541 ttcgtgtcaa cagatgcgtt tcgtgtagta tgcttggact ctgtccttgt ttcactttgt
      601 ctgacagaac gagaggaatc accaaaaagt ttttttcgtc ctgtcgatgt gatttctgat
      661 tggtaatggc cggtataatc cggtaatttt cctttatgct tttccaaatt ttccttacgc
      721 ggagctgact tcaatccatt tgttgcacga cgcttgcgac ggattttctc ggtgttcgtg
      781 ttcgtgaaat gaaattcttt catctgttca aacggggact gattctgttc agtcaaaaga
      841 tcttcttgtc cgtcaaataa tactcgcttc ttgtcgttgg ttaattttac gcctaactca
      901 tcatcgtacg caggaaaacg gaaatgtttt cgtctgattt ctttcattca aaccatcctt
      961 ctcaaaaatg gaacttttct caataatagc acagattcat tgttttcagt agcaatgcgc
     1021 tgattatttt aagaaaatag cgatgaattt cataaatata tatatagtaa taagacttaa
     1081 ttcgttgtct ctctgataac tagttcagga aaaaaacgac gataaccttg actcgcccct
     1141 ttttcttcta ttttttttaa caacatttct ccacatactt cacccatacg tataatatct
     1201 tgcttgatcg ttgtcaattt aggtgaactg atttggtcta aaaatacccc atcaaatcca
     1261 atcacaccaa attcttcggg caagtgtcct ccagcattta taatccctct tactgctcct
     1321 agtgctagcc gatctgaact acatacaaaa caagttttat ctgtaaaatc tgcccagttt
     1381 tctgtcatat atctttctac ttctgtcgaa tgatttggaa accgcaagat tttactagga
     1441 agatcaactt ccttcatcac agataaataa ccagtttccc ttgaaatttc aaaaggctcg
     1501 tccacttcga taccgatata aataatcgtt tgataatctc tttctaaggc atattgcgtt
     1561 gcttttgctg taccatattc attatcgctg tctacataat catatccttc agaattttcc
     1621 ccaaacaaga caactggttt ttccaaacgg tcgatccaat cgaagtcttt ttttctgaca
     1681 cctgtgatga tgtatccatc acaagaaccg acgtcgaagg catcatttgt aactaattgg
     1741 agagaataat gcgctttacc gatccgttta gcgattccca tcagcaaatt catgtaatag
     1801 ggctcagttg tgtcgatttc ttccagtata aataatttga tgatctgcga ccgattcgtg
     1861 acaagtgctt ttgcagcaat atttggacgg taatccagtt cagccattgc tgagaaaact
     1921 aactctttca attcgtcagt cacctgttcc ggatgattga tgactcgaga gaccgtcatt
     1981 tttgaaacat tggcacgttt tgcaacatct gctaaagtgg gcatgctctc ttcctttcta
     2041 acatgttgtc attcttacta tcaattatac caaattttcc taacagagtt tattatagcc
     2101 caaaataaaa aacggaaaat cctctatcgt catgagtgat tttccgtttc aattatttat
     2161 acttttttat caaatttttt gctaaaaaag tggaagcttc ttccattagt ggtatttgta
     2221 ccatatgtcg ctgtgttttt gaggaacgaa aaacaatttc ttttccgtaa gacttatgcc
     2281 gatttttttc tacaaatcgt tccgtttgta tataagggat tttttcgtca gcttgtccat
     2341 gccaaaagaa cagaggacgt ccagctaact tttccggctg caatgacaaa tcatagctct
     2401 taacccatga aatcaaatca aaatagtctt ttggtacgac ataattatat tccgatgcgc
     2461 gccttacgat ttcttttcca tattccaaag gtgcagggga acccatcaaa cacacgcccg
     2521 ctactatatg aggatgttta gccaacaagg cgcatgttgt cattcccccc atcgaaaccc
     2581 cgccaactgc aagctgatca tgtagaagac ctcttttttc taaatgcttg ataagtgtgt
     2641 caaattcaaa cagatttccg tagatactat cccaaaatgt ataggatgga atagaagaaa
     2701 ccggctgttt gcgctcccca tgattcatcg catctggcag gatcacacga atgccctgct
     2761 gcgcaatttt tcttccttgc gtcaaaacta actccttact tgtctgccat ccgtgataat
     2821 agatgacaac gggaatacgt tcctctctta attctttcag aacaacttct aacactggaa
     2881 tatgatggac agaacgtttc aatataattg gattcaattg ttactcacct attttcatta
     2941 aatttcctga tcgccatagc aaccatgctc caacagttgt ctggaacagg ttcagtgtac
     3001 caaataatat aaatgcagga ctgaatggct cgggaaataa gcacagagaa caaagtccca
     3061 ccactcctaa tgctagcgaa aggagtggat aaatagaaaa attcaaaaaa ctggcaacgc
     3121 taccgaaaat attaccaata aacagtatca aaaagaaaaa aacgcttaaa attaaaccat
     3181 ctgtcagcga catctgaaaa acaatgttct ctacctcaat tggctgttga atcgaataga
     3241 cacctaagta tatactgaga aggagactta gcacgtggct ggcacaaaac acacgattga
     3301 ccgttttcat tttaatcacc taacctatct ttataattct attataatca ttttatcatt
     3361 tttttgtatg tataaagttt caatttttct tcacttacga ttttttttga tattgttgtt
     3421 atataaatga aaggagtttt acaaatgatt gatccaaaaa tgttggggat gatcttcctc
     3481 attaattttg cttatatcac tctgaacacg ttacgtttca tgttgacaat gaaaggctat
     3541 cgactgattg ctccacttgt cagtatggtc gagatcacga tttatatcgt cggcttatcc
     3601 cttgttttag atcgtttaga taatccactg aatttatttg tctatgcgtt aggttacgca
     3661 gtaggtatca gtgtcggaat tttgattgaa gacaaattgg cattaggata catcatggtc
     3721 acaacgattt tgccagcaaa tagcgcagaa gataaaagtt tgccgggtat actgagagaa
     3781 cacggttatg gtgtgacaca gacttctgca atggggctgg aaggtgagcg gctagttctc
     3841 gaaatacttt ctcctagaaa aagcgaacgt gaactgtatc gcctgatcaa agaaatcgaa
     3901 gagcgtgctt ttatcatttc ttatgagcca aaatatattt caggtggttt ctggactaaa
     3961 aaagtgagaa aacgacaagg aaaataactc acaaacttaa aaactgtcta atatctaaat
     4021 taaattttaa atgttagaca gtttttattt attattttga ttaaaaaaca tcgacatata
     4081 ctcatcaatt tgttattata ctttatatac ttatcaattt aatttggaga tattatggaa
     4141 attcaacgta gaaccactaa ttttttacat ttaggctctt tttttgcaac tttgacgatc
     4201 ttattttttc tatgttattc ataccttaag acctcacatg cgccttctag tgcattaggc
     4261 tggttgcttt tggatcattc tgatatcaca gaagccgaag aaaatccgtt ttttttgatt
     4321 ttgtcttctc tttgcggctt actgttttct gtttatttcg gtgcctattt ttttcatcga
     4381 catcctggta cgttaaacga agcttcaagc gtattgattg catttaaaac gttttctttt
     4441 ttagcaattc ttttttattc gtttaatcac aatacgcttt tcttctttat catgaatggt
     4501 ttagtcgtga ttttatccat ttttacttat tttatttttt cactcatttt tagccaattg
     4561 aaatgtccgc tcttctttcg attagttcct gtcacctgtt ttatttacag cttgttttcc
     4621 ttttttgtcc ttgctttaat gccactgacc aacccttcga cgatccaagt cgcaggaaat
     4681 ctgttggata tgctcttcat cgtcagtcta ggtgtattta tgtggcaaag aaaaaacaaa
     4741 caaaataaaa agcattttga agcctgacta ttacgacttc ataaatgctt ttttagtttt
     4801 aaacacttca atctaaaaga ataacccaag attggataaa ttattaatga ctcgccattc
     4861 gtttcttagt gattctggat tatcaaatgg acttcctaat ctaatcagct agttcttccc
     4921 ataaaatgcc atacttgact gaatcataat attgattatt taaaaatcta acttttctta
     4981 tcactacttc ctttgtcatt ccacatttct caccattttt ttgcattcct ttgtttccag
     5041 accatgtagt gaatctaata ggtggtagat aggcaaaata ctcaaataat tcttttaacc
     5101 ataaaggaag agaaaggctc ctcctgcaag agtcagtata atttttgctt actgctctct
     5161 taggttttac tcactaaaac tgttccatat tctttgatat aagaaaatgc atgcggtata
     5221 aatttcttgc tcagctcaga aaagatttgt cgtttaagaa aggctatttc ctccattgtc
     5281 aatgaaggat ccaatgttgg taattcaatc tcaaaattgt ttttttcgac aataggtaat
     5341 tctaatgtga atgattcttc ttcctttata gtattcgtca caagtagaga ctgatggaaa
     5401 atactaggcc ggcgattttt atatttattc ttacgtatcc tgtcaacgat aacttctatt
     5461 tgatcaaaaa agtacgattc atttacgtct ccaataagtt cggctaattc tttgaatgcc
     5521 ttcgttacag gaagctgatt cttctgtaca aaaaagtaat tagccaaagt aagcgggaag
     5581 tgttctatag aggaaagtgt gataaaacgg tacttctcat ttcctgcagt tgtcctcagc
     5641 aattctgtct ctcggctgtt tcttactcca taaaaatacg cttctttccg ttcatcttcg
     5701 aaacaatacg cccaaataac ttctcccatc gctaattttt gttcatcaac agagagtctc
     5761 ttcaattgtt cagctatggt ttcagcagcc gaagtggctt gttgcaagta atctttagga
     5821 tcaaatattg gaaagttcaa atgatatctt cgttcttccc tcttgattaa tcctgcatcg
     5881 atcaataaat caagaaaatg ggaaaattta ttttgcgaaa attctttttt caattctctt
     5941 agaatcgttt cttgttctcg atgttcatat agataatcgg tcaatgaaga aaaaagcgga
     6001 tcatcggtca gtttttgata aaagttttcc ttattttttg aataatagtt catatatgtt
     6061 ctcttttcta tccgttttat tttacttaaa aggcttttac gtaaaaagga ggaagaacaa
     6121 gagtcataat tgactgttat tctcctccat ttcttcggcc tttagtatgt tctatgtttc
     6181 tttttatatc aatcgcttat ccattcattt tgaatgcttc atactaccat ttgattagct
     6241 aaatacagcc gtcaattgag gtacgacttg ttttttacgt gaaacgacac ctttaagcaa
     6301 agcacggttg ttggtcaaag ttgtttggaa agcttcttct actttttctt ttcctttacc
     6361 agcaacaagt aattctgaat cactgtctaa gatgtttgtg acaactaata cgaacagatc
     6421 gtagccattt gctttcattt catcttccat tgctgcttct agctctgctt gtcgatccat
     6481 cacttcatta aggtccactg tattgacttg agcgatacga acgttggaac tgcccattgg
     6541 gaaacttttt gcatccaaat caagaagaac cgcagctgat ttatcactta gatttgttcc
     6601 tgctttcaac atttcaagtc cataagtgtt tagatcgact tcagcgattg ctgcaagttc
     6661 ttttgcagct gcttcatctt caggcgtaca tgttggtgat ttgaacaaca atgtatctga
     6721 aatgatagct gagagcatga ttcctgcgat ttctttagga attgttactt ggttttcttt
     6781 atatagtttt aaaataatcg tacttgtaca tccaactggt tctgcacgat agtacaatgg
     6841 attagctgtt tcaaagtttg caatacgatg gtggtctact acagctaaaa tatttacttc
     6901 gctgatatct gaaatacttt gttggaattc attatgatcc acaagcatga catctgcatt
     6961 ttctgcttta gctgactcta ctactcgtgg tgcagatagc tgaaagtggt ctaatgcgta
     7021 ttgtgtttct tcattaggtg tacctagagc aactgcttct gtttctttac ctaattcatt
     7081 ttgcaagtgt gaaaacgcaa tggctgcccc gattgcatct gtatctggat tttggtgacc
     7141 aaaaactaaa atttttgaca tgtcattcgc tcctttgtga tttctcctat ttaataatag
     7201 caaaaaaacg gaaagaagca atacttatct tctttccgat gcgacctatc gcgttaaata
     7261 ttttgtatac tcttctgtat gaagcaatcg tttagcattt tcgacacgtt cttttgtagg
     7321 tggttcgatc ccttctaatg gatatttcaa accaagtgtt tcccacttgt attttcccat
     7381 cgtatgataa ggaagaatct ctactctgtc tacatttgac aaggtttgaa taaagttgtc
     7441 tagtcggatc aaatattcat cataatcact tcgctcagga actagtacat ggcgaatcca
     7501 aaccggtttg ttgatttttg acaaatattg agccatttct aaaatatttt cattgtccca
     7561 atgcgttagt tttttatgct cttcattatc gatgtgtttg atgtcaaata acagtaaatc
     7621 tgtatacttc atcaattctt gaaaacgtga aaagaaaggt tcttcatacg taaaaggttt
     7681 tccgcatgta tccaatgtag tatgcatctt ccgctctttt gcttttttaa atagttcgat
     7741 caaaaaatcg atctgcaata gaggttctcc accactaaca gtaataccac ctttatctcc
     7801 ccagtaaggt ctgaagcgtt ctgctttatc taaaagttca tctgctgtgt attctttccc
     7861 tccgccaata ttccaagtat ctggattgtg acaaaattgg caacgcatgc ggcatccttg
     7921 cataaacacg acaaagcgca gtccaggtcc gtctactgaa ccgaaagttt cgatagaatg
     7981 aacatagccg attgtttttt cttccattta agttcacatc ttttctttga tttcatttta
     8041 agtacaagtt agctgtcgaa gcgaagcttt ctgaacaaaa tttttcgcaa ttgccgcttc
     8101 gttatgtgta aaatttacag ggacggaaca tacaagtcct gcccctgtaa atcgtttctt
     8161 tcaaataagc atactgatta ttcgattttg atgcgatggc tattcaacgt cctttcgacg
     8221 ctaagtcgaa aaactttttt cacgaacttt ttacattctg tcgtgtgaag ttctcatcaa
     8281 gacatctaat tgttgttctc ttgtcaagtc acggaattta actgcataac cagatacccg
     8341 gatcgtcaag ttcggatatt tcattggatt ttccattgca tcacgcaata aatcattact
     8401 gaatacattg acattcaaat gataagctcc ttttgagaag tatccatcta agacattacg
     8461 caagttttcg attcttgtat cttgttcttt tccaagacct gaaggattga ttgtttgggt
     8521 atttgaaatt ccatccaatg cacagccgta attcatttta gctgttgagt tcaggctagc
     8581 taataaccca ctttgttccg cattgtaact tggatttgct cctggcgcaa gtggttttcc
     8641 agcttcacgg ccatcaggag tatttcctgt atttttaccg taaacaacat ttgaagtaat
     8701 cgtcaataat gaagttgttg gttttgagtt gcggtaagtt ttatgacgtt tgatttgtcc
     8761 catgaagtat tccaagatcc atgaaactaa ttcatctgca cggtcatcat catttccgta
     8821 tttagggaag tcgccatcca cttcaaaatc aactgctatt cctttttcat tacggattgc
     8881 ttttactttt gcatatttga tcgctgacaa gctgtctgcc gcatgagaga tcccagcaat
     8941 acctgtagca aatgtgcgtt gcaagtcaga atccatcaaa gccagctgag ctgcttcata
     9001 agaatattta tcatgcatat aatgaatgat gttcaacgta ttgacatata gttctgctaa
     9061 ccaatccatc atattcatga agttatgttt cacttcttca aagtctagta tttctgatgt
     9121 gattggacga tattctggtc caacttgggc gccagtcact tcatcgactc cgccattgat
     9181 ggcatataat agtgttttag ccaagttagc acgagcgcca aagaattgca tgtcttttcc
     9241 gacaactgtt cctgatacac agcaagcaat cgcacaatca tcagaacccc attgttcacg
     9301 aagctgatta tcattttcga attgaatcga agaactttcg atagcgattc tgctagcata
     9361 tgttctgaat ccttctggaa ggtgttcaga atacaaaaca gtcaagtttg gttctggtga
     9421 aggtcccata tttgttaatg tatgaagcag acggaaatca ttctttgtaa ctaatgaacg
     9481 accatctaat cccatacctg caatggataa agtagcccag atagggaatc ctgagaataa
     9541 ttggttatat tcaggtgtac gcgcgaattt gaccatacgt aatttcatta ctaagtggtc
     9601 gatcaattct tgtgcttctt tttctgtgat tactccatta tccaaatcac gttggatata
     9661 gatatcaagg aatgctgaga tacgtccgat tgacatcgca gcaccatttt gtgatttgat
     9721 tgctgctaaa tatccgaagt atagccattg gacagcttct tttgcatttg cagctggttt
     9781 agaaatatca tagccatatt tcgcagccat ttctttcatt tgcgctaatg cacgatattg
     9841 ttcagtgatt tcttcacgta aacgaatcac ttcttcactc attgtatgat aaccagtcat
     9901 atcatgatct tttttctttt gttccatcaa atagtcgatt ccatacaatg ccacacgacg
     9961 atagtcaccg atgatacgtc cgcgaccgta agcgtctgga agccctgtaa tgattttgtt
    10021 tttacgagca gcacgcattt cagcagtata agcgtcaaat acaccttgat tatgtgtttt
    10081 gcgccagtca gtgaaaatat gtgtcaattc atcgtttggt gtatagccat tgctttttag
    10141 cgcattgtta gccatattga ttccgccgaa cggcatgaat gcttgtttca aaggtttgtc
    10201 tgtctgtaga ccgacgattt tttccaaatc tttatccaaa tagcctgcat cgtgtgaagt
    10261 aatagttgat acgatttctg tgtccatatc atagacaccg ttacgctcga attggatatc
    10321 atttaacttt tgcaattcat cccataattt ttctgttgct tctgttgggc cttccaaaaa
    10381 gctgtcatca ccgcgatatt cagtgtagtt attttgaata aagtctctag tgtctacgcc
    10441 ttctttccat ttggtacctt taaatccatt ccattgctcc attgtatgga cctcctaaat
    10501 ttctgtttta tgtaacagtt tttacgtgat tagtataaca cagcacccta tctttgcaag
    10561 ggttttcttg ttttttattt aacaattttt atgttttatt tacatatatt taaatcaacg
    10621 ttgacatacc aacatttaag cattgtgaac actttcatct ttttttgcaa acgtataagg
    10681 atttattaaa aatgaatgaa aaagagacgc cacctgtatt aatacagatg gcgtctcttc
    10741 attaaaatac tacaacagtt acgactcgat gaaaatctca ggagcatcga taacttcgat
    10801 gacttctcca ccttttttct catccatcgc aaatgatcca ttcgatgttc gatcacctat
    10861 agggaaatca gttgggtcaa tcgttaactg ctgccctttt tgattcatca aggttatttc
    10921 ttttgatctt ccttccgaca tatagataat acggtgcgga ttttttttca gctcacgcat
    10981 gaccgtcact ccccgcttcg cacgtgaagt ttggctgatt tcttgagcaa gcatgcgttt
    11041 aacagctcct cgctgagtaa cgattacgat cggcgtatca ccttctgcta acacaagcag
    11101 cccgttgata atcctatctc catctttcaa attcatagac ttcactccag ctgcctttgc
    11161 tccaacaacg ggaacatctg ttaaaggata gcgcaaaccc attccttgat gcgttactaa
    11221 gaaaacatct aagcctggct gatcttcttt cagatacaca gcaatcagtt catcttcttc
    11281 cgcctttagc ttcatacagc tgagcggacg gctcttatag gtgcgccatg gttcgaactc
    11341 tgtcattcgt gtttgcttga tcaatccatt cttgctgatg aatacaaatg ttttctctgc
    11401 ttgaattttt tgatatggga aaacagctaa aatcgattcg tctacagaca gattggagat
    11461 tgtttgagaa atgtgctcac cagcatcttt ccatttcaaa tcgggtagtt catggacagg
    11521 gcggtagatc acatttgctt tatttgtgat cagaagaaca tggtccaatg tactcaattc
    11581 acctgagtat agcaagtagt cgccttctcg catcccgatt tcttctggtt tggaagcact
    11641 ataagaacga aggcttgttc gcttcacata gccttctcgc gtcacactga caattacgtc
    11701 ttcttgtgcc actaagactt gcgtatcaat tttgatttct tcgatttcgt cttcgattgt
    11761 cgttagacga gcggaagaat aatttttttt cacttctcgc aattcttttt tcataacaga
    11821 gaaaagctct ttgtcatttg aaaggatttt attcaactct gtgatttgcg caatcaagct
    11881 ttcggattcc ttttgaagct ctgtgatatc cgtgttcgtc aaacggtata attgcaatgt
    11941 gacaattgct tctgcttgtt cttctgtaaa ttgaaagacg tcgactaaat tctttttggc
    12001 gtcttttttg tctttacttt cacgaatcgt tgcgattact tcatccagaa tcgataaagc
    12061 tttcatcaat ccttctacga tatgctgtct tttttgagct ttggctaaat cgaattgact
    12121 acgttttgtt atgacttgct ttcgatgctc gatataactt cttaaaatgt ctttcagtcc
    12181 aacttgatgc ggagtcatat ggtcgatagc gaccatattg aaattgtaat tgatctgtag
    12241 ctcagtgttt ttgaacaaat aattcaaaat tccttgagca ttggcgtctt ttttcaattc
    12301 gacgacaatt tgcagacctg ttctatcact ttcatctcgt acttcagcta ttccatcgat
    12361 tttcttattc aaacggatct catccatttt tttcaccaag gtcgctttat ttacttcata
    12421 tgggatttct gtgatcacga tttgctgttt attacccttc attgcctcta tctttgtttt
    12481 cgaacgaaga ataacttttc ctcgtcctgt ttcataagct tttttgattt catcttttcc
    12541 ttgcaagatc cctcctgttg gaaagtcagg tccaggaata tattccatca atttttcaag
    12601 gctcgcttgt ggatgatcga tcatatagat tgtgccatcg atcacttcag ctaagttatg
    12661 agtcgggatt tctgttgcat atccagcaga tatacctgtc gatccattga cgagaaggtt
    12721 tgggtatcga gctggaagga ctgttggttc tttttctgta tcatcaaaat tccacacgag
    12781 atcgactgtt tctttctcga tatctgctag catctctcca cttaacttgg ataatctggc
    12841 ttcagtataa cgcatcgcag caggtggatc accgtccata ctcccgttat tcccgtgcat
    12901 ttcgatcagt acttcccgca acttccagtc ttggctcatg cggaccatcg cttcataaat
    12961 actgatgtca ccatgaggat gataattccc catgatattt ccgacagatt ttgctgattt
    13021 acggaatcct ttgtcatacg tattgccatc tttgttcatg gcaaataata tccggcgttg
    13081 cactggcttc aatccatcac ggatatcagg cagtgcacgt tcttggataa tatatttgga
    13141 ataacgtccg aagcggtcac ccatcacttc ttctaaagtt aattcttgta cttcttgtcg
    13201 attttccatc aggtgacctc ctattctact tcaaataact gattgttttc atttttatct
    13261 gctcgttctt catctaataa atcattagaa actgaaggag agatttcagt atcctctttt
    13321 ttatctaaga tactgccatc ttcttcgagc gtaaattgca cgtgattttc gatccatttt
    13381 cttcgaggtt ctactttgtc acccatcagt gtggttactc gacgttcagc ttgcgcagca
    13441 tcatcgatac ggacgcggat caacgtacgg gaagtcggat ccatcgttgt ttcccacaat
    13501 tgttccgcat tcatctctcc aagtccttta tatcgctgca gcatatatcc tttgccgact
    13561 tttttaatca ttgctgccaa ttcgtcatct gtccacgcat attcaatgac ttgcttcttt
    13621 ccttgtcctt tggatacttt atataaaggc ggtaacgcga tatatacttt cccagcttca
    13681 atcagcggtt tcatataacg ataaaagaaa gtaagcagta atacttgaat atgggcgccg
    13741 tctgtatccg catcggtcat gatgattact ttgtcgtaat tacagtcttc gatagaaaac
    13801 tcaggaccga ctcctgcacc aatcgtatag atcatcgtat tgatttcttc atttttcaag
    13861 atatcttgca ttttagcttt ttcggtattg atgacttttc ctcgtaaagg tagaattgct
    13921 tggaactttc tgtctcttcc ttgtttagca gatccgccag cagaatcccc ttcgactaaa
    13981 tacaattcat ttttcttagg gtttcgggat tgtgcgggtg tcaattttcc tgaaagaaga
    14041 gattcgcctt ttttacgctt cttcccattt cggctttctt ctctggcttt acgtgctgct
    14101 tctctcgctt ctctggcttt gattgcttta cggaccaaca tctggctcat ttcgctattt
    14161 tcctgcaaat aaaagcccat ttgttcactg atgacgttat ctactacggt acgagcaact
    14221 ggcgtaccaa gtttttcttt tgtttgccct tcaaattgca gaagattttc aggtacacgg
    14281 atagaaagta cagcagctaa cccttctctg aaatcactac cttccagatt cttgtcccgt
    14341 tctttcagca aaccaacttt tctcgcatat tcattataag atttcgtcat cgccgctttc
    14401 ataccagctt catgggttcc cccatctttt gtccgaacgt tattgacaaa agataaaaca
    14461 ttttctgaat aaccgtcatt gtattgataa gcgacctcta cttcgatacc ttctttttct
    14521 cctgaaaaat aaacaactgg tgtcaatgta tctttttctt cattcagata atcaacaaat
    14581 tctttgattc cttcttcgta atgaaaaatt tccttgactg gttcttctcc acgaagatca
    14641 gaaagagaga ttttaacgcc ttttagaaga aaggcagatt ctcttaaccg ttcggctaaa
    14701 atttcatatg aaaatttcgt tgtactgaat attgtatcat ctggtaaaaa atggacagtc
    14761 gtcccgtttg ctttttttgt ttttcctatc tttttcaaag taccgtcagg tttaccgccg
    14821 tttttaaatt tctgctgata ctctacgcca tctctaacga tcgttacaat tagccatttc
    14881 gataaggcat ttaccacact ggctcctaca ccgtgcagtc caccagaagt tttgtaccct
    14941 ccttgaccaa actttccgcc agcatgcagc acagtaaaaa tcacttcaac tgttggtatt
    15001 ccggaagcat gcattcctac aggcatccca cgtccgctat ctgcaacagt tatactattg
    15061 tcttcatgga tggtcacatc aatctcactg ccataacctg ataatgcttc gtcaactgca
    15121 ttatcgacga tttcatagac taaatgatgc aagcctcggc tgtcagtgga tccaatgtac
    15181 atccctggtc tttttctaac tgcctctaat ccttccaata cttggatgga cgagtcattg
    15241 tattcgttgt ttactttttt tgccaaggca aacgctcctt caataatact ttgcggcaaa
    15301 accgcaccac gattatcata ctagaaaagg tcgtgaaaaa aaagagggta gacgagaaat
    15361 caattttaat tatctcctaa ccgctttttc gacattcccc tctatcgatc atctcttctt
    15421 tgtggtcatt tttatttttg gttttctttc aacttaccaa gttcaatctt aatacaacga
    15481 tccattacga tatctgtacg tcctgctttt cttagcatct cagctgcttc tttgttttca
    15541 atccctaatt gtgcccagaa cactttagca tcagttttca aaaaatcacc tgctatttca
    15601 ggtaaaaatt cactccgtct aaatacatct acgatatcga ttggatcatc gatttctgtc
    15661 aaattcgcat agactttctc gcctagaatt tcttcaccag ccaataatgg atttactggt
    15721 atgattttat atccattgtc ttgcaatacc tgtgcaacca tgtaacttgt tcgttctggt
    15781 ttattgctca agcctacgac ggcaatattt tttgcttctt ccaaatagtt gaaaatcgtt
    15841 tcttgtgttg gattttttac agacatttct gccacccctt gcttttcttt ttattccatc
    15901 tattatactt gtatctttca ttttttcaat tgttcctgtt acctattcat gctaaaataa
    15961 aggatagttt tcaacttgaa agagggtaaa aaatgaaatt gatcttatta cttattttag
    16021 catatctttt aggttctatt ccttccggtg tctggattgg caaattgttt ttcaaaaaag
    16081 atatccgaca acacgggagc ggtaatactg gaacgaccaa tacatttcgt gtattaggca
    16141 aaacagccgg gattgttgtc ctgcttatgg atattttaaa aggtacattg gctacttgtt
    16201 tgccgatgat cttccacctt tctgggatta accctctttg gtttggggta tgcgccattc
    16261 ttggccatac atttccgatt tttgctgggt tcaaaggagg aaaagctgtt gcgacaagtg
    16321 caggaatgct tttaggattt aatcctgtat tttttgttta ttcttgtatc atctttatcg
    16381 ttagtttatt ttgtacaagt atggtgagtt tgagcagtat gatcagtgca gtattgatca
    16441 ctttatctac gatcgtcctt ccttatgtag ctcctgtgat tttggctaag cccaattggt
    16501 tactgacgat cattgccttt ttagtttctt cctttatctt ttatcggcat aaagacaata
    16561 tcaagcgtat cagaaaccat actgaaagtc gaatcccgtt tggtttgaat agcagcaaga
    16621 aaaaatcctg atactttttc attccaaaga gataaaacgg gagtgtgaca aatcgatgtc
    16681 acactccctt attacttaca ggatagcttt tttacacacc ttggtaaacg gtgttccctg
    16741 ctaacttctc ggtcacaacc tcttacttca ctgtgatgga atattttgtc ttgaagattt
    16801 catgggcacc tagttgattg atccctactt tttccatcaa gtttccacta ctgttcaccg
    16861 tgtcagcgat tccgcaccac ggttcgatac aaacgaaagg cgcttctttt ggataaggag
    16921 accagatccc tacataaggc atatctttat agcttaaagt tacgctatgg gaagattttt
    16981 cacttcgaat ggcgtacgca tttagacccc ttgtttcaaa aaccaaggca tcttgctcaa
    17041 aaagttcacg attcaaagcc agattcgtat ttgtctgacc taacgtcttt tgatccatat
    17101 cgatgaatgg gcctttcaat ggtaggcgta atcttgattt caatggagaa aatgccagat
    17161 agaaatcttc aaatgacaat ccttcttcaa gaggtacatt gaaagcagga tgtccaccga
    17221 tagaaaagaa catttctttt tcaccggtat ttgccacttg ataatgaacc gtgatgccgt
    17281 ctcctcctaa ttcatagctg atcactaatt caaaatcaaa tggatacttt tctaatgtct
    17341 ccggcgtact ccttaagatg aaactagcca tttcttgtcc atgttcaatg acttcaaaat
    17401 ccatatcccg agcaaatccg tgttgcccca tttgatatgt tttcccttga taaacatact
    17461 gatcatcttt taaacgtcca acaaaaggga ataaaaccgg tgcatgtctg ccccaatacg
    17521 ctggatcacc ttgccagata tactctaaac catgttcttt tgatttcaga ctgatcaatt
    17581 ccgcaccgtg ttcagcgatt tcggcgatca gctggtcatt ttgaataata acagtcattg
    17641 ccattcctcc aacttcgact tactttttaa aatgggaagg ctggaacaaa catttctatc
    17701 tgccccagtc cccttacttc taataactgt gttttgctaa ctcgtcttta aaacgggaat
    17761 tcaatacttt taaataagtt cccttcatgc ctaacgaacg agattcaatg attccagctg
    17821 attccaattt tcgtaaagca ttgacgatca cagaacgagt gatgccgata ctatcggcaa
    17881 tattagaagc agtcagacga ccttcatctc catccaatgc ttcaaagata gcttgtacag
    17941 ccttcaattc gctataagat aatgtgttga ttgccatttg gacagccgtt gcactccgta
    18001 catctgcttc gatgcttcga gacttctgat aaaggatctg cataccgaca accgtagctc
    18061 catattctgc taagactaga tcgtcatctg caaacgattg ttccatacga gataagataa
    18121 tcgtacccaa acgttcgcca gctccaaaga tcggaacgac agtcgtcaga ccaaatggat
    18181 atttctctct tgactctacc ggaaatgcag taatatcact agtaattggg atattagctt
    18241 cagttttcat caactgtgcc actgtatcag tataagattc aggaaattgt ttctcaacaa
    18301 acattgtttt gattcgttca ttgttcacat cgtgacgttc attataacct agtaatactc
    18361 cgtcacttcc tatgatatag gtgttgctgt caagaatacc acctagtgtg acagccattt
    18421 tatcgtaagg caaatctgct tgcatgtcaa aagtattctt ttgctgcaaa agtgtgttta
    18481 tcttgcgggt tttcgttagc aagtctgtca ttgtcgtcct ccgatttttt ataaaatata
    18541 gcgacttaaa tcttcatttg ccgcaattga gccaagtttg tcatccacat atgcttctgt
    18601 gatcgttatt tctcccattt gcatatctgg tgcttcaaat aatagatctt ctagtagttt
    18661 ttccaaaatg gtatgcagtc tgcgtgcgcc gatattatct gtgtcacggt tgacatcgaa
    18721 agcgatttga gcgatccgtt caattgcttc ttttgtaaac gtaactgaca cattttctgt
    18781 accgatcaac gcgacgtatt gttttactaa agcattattt ggttcggtca gaatcttcac
    18841 aaaatcttca gctgtcaaat catctaattc tacccgtatc gggaagcgtc cttgaagttc
    18901 tggaattaga tcacttggtt tagacaaatg gaaagctcct gaagcaatga ataggacgtg
    18961 atctgtttgg atgatcccgt attttgtgtt tacttgtgaa ccttcgacaa ttggcaatat
    19021 gtctctttgg acgccttctc tggatacttc tccagattgc tgtgatttag aagtgatctt
    19081 atcgatttca tcgataaaaa taattccact ttcttccgct aatttgattg cctcactatg
    19141 gatatcagca tccttgacta attttgctga ttcttccttg atcaataact ctaaagcttc
    19201 tttgactgtt accgtccgtt ccactttttt cttcggtgtc aaagcaccta gagtttcatt
    19261 taggtcgatc cccatttgct ccaatccatt gttcatcatt ggtgcaggtt tcttttggtc
    19321 ttcaacttca atggttactt cacgactatc cagtaaaccc ttttgtagtt gttccaagac
    19381 tgtacggcga ttgattcgaa tatcttctgt cacttcttct tgcggttcag cggtattttg
    19441 ctgactagca ttaaaaagat tcatcatttg ttcaaattga ttagtggatt gtttctgttc
    19501 ttttttgata ccaggtacca agatttttac caaacgtttt tctgcatttt ttttagcact
    19561 tgtgtataca cggctgtact gctctttttc tacgatttgg atcgcatttt ctactaaatc
    19621 ccgaaccatt gattctacat ctcttccgac ataaccgact tcagtaaatt ttgttgcttc
    19681 gactttgaca aatggtgcat tgacgatttt tgccaaacgt cgtgcgattt ctgttttacc
    19741 gacccctgta ggtccgatca tcagcatatt ttttggtgta atatcttgtt gcattttttc
    19801 atctaactgc aaacggcgat agcggttacg caaagcaacg gcaacagatt tttttgctgc
    19861 gtgctgtcct acgatatatt catctaattc acttacgatt tgtcttggtg tttgttttaa
    19921 ttcatacata tctactcacc tcttacagtt cttctacgat aatattatga ttagtaaaga
    19981 tacagatatc tgcggcaata tttaacgcat tttctgcaat ttctttcgca ctcatgtcgt
    20041 tttgagcata gtttttcatt gctcgggctg cagccaacgc aaaattccct cctgatccga
    20101 tagctaagat accatcatct ggtgtgataa cttctcctgt acctgaaaca agaagcattt
    20161 ctttatcatt cattacgatc agcatcgctt caagtttttg catagattgc tgtgtccgcc
    20221 attcttgagc taattcgaca gctgcgcgtt gtagattccc gttatattcg tttagtttgc
    20281 cttcaaattt ttcttctaaa gtaaacgcat ctgcaacact tccggcgaaa cctacaacaa
    20341 cttctccatt gtagatacgt cgtactttct ttgcagtgcc tttcatgaca acagattcac
    20401 ccattgttac ttggccatct ccagccatag caaatttccc gtctttttcg acggcacaga
    20461 tagtggttga atgaaatggt gattcgacca tgtttgtttc ctcctaaatt tgttcttttc
    20521 cttattttta cgctcttgga tggaaagaac gatagttttt ttgtaaactt tcttttgtta
    20581 catgggcata gatctgggta gtcgataaat tggcatgtcc tagcaattct tggactgtcc
    20641 gcaaatctgc cccattattt aataaatgag tagcaaatgt atggcgcagc atgtgaggat
    20701 ggatatcact atccaaactg ctttttttga tcatttgatt caagacatat tcaattccag
    20761 taggcgtgat tggttttcca tgatgattca caaaaacgat atcatgctct tcgtgatatt
    20821 ttgtcatcaa tacctggcgg ccttccctga aatattcttg cagagcatct tgagcaaaag
    20881 aacctagagg agcatatctc tctttgttcc ctttaccatg gatcaacatg acctctgaat
    20941 caaaatcaat gtctgatacc gacaaactgc tacactcact taaacggatg cctgacccgt
    21001 aaaggacttc cagtaaagcg cggttcctca aatccaaagg actatctcct gctacgctgt
    21061 caaaaagtgc ttgcatttca ttttcataaa aaaaacgtgg cagtctcaaa tttttctttt
    21121 tgagatgaac gtaagaaaat ggattttctt ttatcacttc ttctttgaga agatactgat
    21181 aaaacgaacg taggctggct atcttgcgac tgatagaatt tctgctatag ctaggacgat
    21241 gatcagctaa tgcactcaaa tagacacgaa ccgtaaaata ttccgccttc agcagatcag
    21301 cgtctccaga ttcctccaaa aaatgtttga aatggagaat gtcttcttca tatgcttctt
    21361 tcgttttttc tgaatatcct ctttcgacaa tcaaataacg caaaaatttt tgttcccacg
    21421 tggcttctgt cattttctca ccttcctttt gtcccagaga ataatttagc acagcgttta
    21481 taaaaagaca aataaattgt cagaatttaa ccaatatttc taagtttgtt cacaattggc
    21541 gcaattcctc acattttgtt tgagaaattc ttaagaaaaa cgcaagaaaa agagcgagac
    21601 tatccgtctc accctcttca tggagtttcc ttactcattt gggattgcag ttttttctaa
    21661 ttctgttttt attgcctcat tagcttttaa agctcgttgt gcaattgctt catatcttgc
    21721 ttttttgtct cgaatgcgct ctggcagttc aggaaacaga ccatagttgg cattcatcgg
    21781 ttggaaatgt tttccttccg catgagtaat gtagtaagcc atacttccaa tagctgtttc
    21841 ttgtggaaac tcgactggtt ccatttcttt tgctaagcgt gcggcgttga ttccagcaag
    21901 tagtccgctc gctgcacttt caacatagcc ttctacacca gtcatctgac ctgcaaagaa
    21961 cagatcttcg cgtttcgttg attggtaagt cggtttcagc aattctggcg aattcataaa
    22021 gctgtttcgg tgcatcacac catagcgaac gaattcagca ttttctaacc caggaatcat
    22081 ccggaaaaca cgtttttgct cgccccattt caagtgagtc tgaaagccca cgatgttgta
    22141 taaagaagct gcagcattgt cttgacgcag ctggataaca gcataaggac gtttgccagt
    22201 tttaggatct tccaatccaa ctggtttcat aggtccgaaa agcatcgttt tgaatcctcg
    22261 ctgtgccatt acttcaattg gcatacatcc ttcaaaatat ttttctttct caaaagattt
    22321 aagttctgcc acttcggcat tgattagtgc ctcatggaaa gctttgaatt cctcttctgt
    22381 catcggacag ttcaagtaag ctgcttctcc tttgtcatag cgggacttca aatatacttt
    22441 atccatatcg atcgtagctt tgtctacgat tggtgcagct gcatcataga aataaaaacc
    22501 atctgaacca ttgaatgctt tgatgctttc tgctaatgga tgagaagtca aaggtcctgt
    22561 tgctactacg gtgattcctt ccggtatttc agtaatttct tcgtttatca ctgttactaa
    22621 tggatgctct ttgacttttc gggtaattgt ttcagaaaaa gaatcgcggt caacagctaa
    22681 ggcaccacca gctggcactg ctgtttcatc tgccgaagtg attactaccg aattcaatcg
    22741 gcgcatttct tctttcaata accctactgc attagccaaa ctgtttcctc ttaatgaatt
    22801 ggaacatact agttcagcaa aattacttgt gtgatgcgcc tcagtcgatt tgactggacg
    22861 catttcatat aaacggacag ggactcctgc ttgtgcgatc tgccaagcag cttcacttcc
    22921 ggcaagccct gctccaacaa catttaccat tttcaatgaa agaacctctt ttctattatt
    22981 tttggatgtc ttcttcgtaa tctccattta cacagactac ttgtttaccg cctttgactt
    23041 tcttctcgac cagatatccg tcacattttg gacaatttct gcccactggt ttatcccaag
    23101 aagtgaattc acattctggg aaacgggaac aaccatagaa tagtctgttt ttcttagatt
    23161 ttcgttcaat gacttgtcct tcatgacata ctgggcaagt cacaccgatt tcttttacga
    23221 ttggtttcgt attccgacaa tcaggaaaat tactgcaagc ataaaacttc ccatatttcc
    23281 ctaattttat caccatcgga tgtccacaga catcacaatc gaatcctgct ggttcatctt
    23341 tgatttgaat tttttcgatt ttttcttccg cattcgtcag ttctttttca aacggtttat
    23401 agaaacgatc aaccactttg acccacgctt ccgtgccttc ttcaatttta tccaaatctc
    23461 cttccatttc tgctgtgaaa tggatatcga cgatttgagg gaagaattca cagattaatg
    23521 aattgacaat ttctcctagt tcagtcggct caaatctttt ttgtgtcaat tttacatagt
    23581 agcgtctttg gatcgtatca agtgttggtg cataagtgga aggtcgccct accccgtttt
    23641 cttctagtgc acgaatcaac gtagcctcac taaaacgtgc tggtggttga gtaaaatgtt
    23701 gttttggttc aatatcaaca gattggacta catcgccttc ttcaagttct ggaagaatat
    23761 tttctttctc ttctttgccg tcatctctac cttccacata cacttgcatg aatcctttga
    23821 atttgatttt tgaaccgttc gcaatgaaga tgacaccatt ttgttctaat gtcactttca
    23881 ttgtatctaa aatagctggt gtcatctgac tagccacaaa acgtgaccag atcaatgtat
    23941 aaagtttcaa ttgatcttta tctaaatatt gtttgagttc atctggtgta cgaagcacac
    24001 tcgttggacg cacagcttca tgggcatctt gtgcgccttg agcatttttg atctttcggt
    24061 gatcatgtct agaaaattct tttccatacg tatcttcaat aaatgctgcg gcctctgctt
    24121 ttgctgtatc ggcaatccgg gtagaatcag tacgcatgta tgtaatcaag ccgactgttc
    24181 cttgtttacc caaagtgatt ccttcatata attgctgtgc taccatcatg gtttttcttg
    24241 ttcgaaagtt taacttacgg gcagcttctt gttgcaggct acttgtagtg aaaggattcg
    24301 cagggtttct tttgcgctct ttcttttcta cttttttaac ttcgaagtct gttccatcaa
    24361 ttctagcagt gacttctttt acactttgtg catctggtaa tttctttttc ttaccgtcga
    24421 ttccccagaa atttgctttg aatttcttgc gagctttttt aaaattaccg tcgatgctcc
    24481 aatattcttc tggaacaaat tctcggatct ctttttcacg gtcaataata atttttaaag
    24541 cgacagattg gacacgtcct gcacttaacc ctttcttgac cttacgccag agaataggac
    24601 tgatcgaata accaacgatt ctgtctaagg tacgacgagc ttgctgtgca tctactaaat
    24661 ctacatcgat cgttcttggt tccttaaaag ctgctttgac tgcgtctttt gtgatttcat
    24721 tgaagaccac ccgatttttt tctttcagat ccaacccaag taggtacgct aaatgccaag
    24781 caatcgcttc tccttctcta tccgggtcac ttgccaagta aactttttga gctttttttg
    24841 ctgcggcttt caggcttttg atgacatcgc cttttccgcg tatagaaata taatggggtt
    24901 cataattgtt ttcaaaatcg atacccattt tacttttcgg taaatctctt atatggccaa
    24961 cactggccat tactttatag tttcgtccaa gatatttctc aattgtcttg gcttttgcag
    25021 gtgattctac aatcactaaa tatttatacg ccattactga atggactcct ttccattgtc
    25081 gtgttcctac tattaaaaga ggattcatac aaatcgtagc taatcatatc cattcagaaa
    25141 acgtttgtca agaaaagcaa atgaaaagta tggtgttatt ctttaaattc tgccaagata
    25201 tcttcacccg aaaccgtgca aactgcaccg tcttggatca aatgatgaca tccggtagaa
    25261 tgttctgtta aaatatttcc tggaacagaa aaaactgttc ttccaagatc caatgcttgc
    25321 tgtgctgtta tcagagagcc gctttttttc ttggcttcaa agacacatgt tcctttagac
    25381 aaagctgcga taatccgatt tctcattgga aaacaatgct ttttcgggcc ggattgagga
    25441 ggatattcac tcaaaagaag atgatcattt gcaatcacct cttgcaagtc acgattttca
    25501 gcaggataga cttgctctat ccctgttcca atgactgcga ttgtccgtcc accatgagag
    25561 attgctgctt ggtgaccgta tgtatctatc cctttcgcgc agccactgac gatcacatat
    25621 ccagcttcta tcactggttt tagtaaataa taaactgttt ttttggctaa agcagaagtg
    25681 tgtcttccac caacaacgct taacatgtta caagaaagta aagatagatc accattataa
    25741 aacagtacaa ttggcggata ggtcaagtga agcagctgag ggggatattt gggatcaaag
    25801 caagtgataa acgactgttt cgattggatt ttgccccagt tagcgtgaat ttcctgccaa
    25861 cttttgcgaa acagctcccg gtgtttggtt attttaccta tcttaatgat gtcttcaaat
    25921 ccgatttctt tataaggata ctgcatcatc cagttagcaa gtgcccattt tccttgacta
    25981 ctgattcctt ttgtataagc aagtttcaat aaattttctt ctatttgata catcataaaa
    26041 ccgcctttcg tctctctttc taataagata cgtaaaagcg gctgtttttt attgtaaata
    26101 tttttttaca ggtgcaaaac ttttacgatg gattggcgta attccttgtc gttcaagtcc
    26161 ttctaagtgt tcctttgttc cataacctgc attatgcgag aaaccatatc caggataaag
    26221 cacgtcatat tctttcatca attggtctcg atatacttta gcaatgatac ttgcagcagc
    26281 aatcgacaca gatcgtgcat cccctttgat tattttttcc tgctgaatag gcaaatccaa
    26341 ggtcatcgca tcgatcaaca aatagcttgg tacaatggac aatttttcta ctgcttggat
    26401 catcgctaat ttacttgctt cataaatatt cacatcatcg attgtctgct gatcaacgat
    26461 cccgatcccg attgccaggg ctttttcttg aacttgttga taaagaagtt ctcgcttttt
    26521 ctctgataat tgtttggagt cattcagccc taatatgatc tcatttttcg gcaagataac
    26581 tgcagctgcc acgacaggtc cagctaatgg tcctcttcct acttcatcaa tgccggcaat
    26641 ccattggtga ccttgtgcgt acccttgctt ttcaaagcaa aacatttctt catatttttc
    26701 cttaattaat gcttcctttt tcaatcgtcg ttcaaaagaa gccagtgctt gctgcacgcc
    26761 tttgcgtgga tcatttctta atgattctag tgtaggatca tctattctct gtatgctttt
    26821 caatcgttct ttgatacttt ggatggattc agtcatcact tttttgctcc atttcttcgc
    26881 aacgatccag tgtgtatcgt ccaagttttc cttgacgaat atcatgcacg actaattcgc
    26941 tgccacgatc atagtcttct ttatacccac gttttgctgt aatatccatc agtaattccg
    27001 gtgccaattt ttcttcttgc tcgattgata aaccataacg atcgctgatt cttcctgaat
    27061 aatatcgggc aaaaaagtct aatccgtaaa tcgctaaatc atctaaatgg acaagctggt
    27121 ctttgatcgc gcctgtcagc gctagttttt tgccgatttc ttcatcttca aatttgggcc
    27181 ataaaatccc tggtgtgtct aacaattcca actcattacc taaacgaagc cactgctgac
    27241 cttttgttac gccaggctta tttcctgtct gtgcaatttt cttgcctact agtcgattca
    27301 tcaacgtaga tttcccaaca tttggaatac ctaagaccat tgcccgaata gcgcgaggct
    27361 tgatcccccg agcagcatct cttgcccgtt tttctttcaa tgcttcttta gccgcaggta
    27421 ctagaccttt aattccttta ctttcttgtg ccgtgatagc taatgcaaga tggccttgtt
    27481 tacgaaaata ttcttgccac agctttgtct gttgtggatc tgccagatcc gctttattca
    27541 ataaaacaag gcgaggtttt tgctgaatga tctgatctag cattggatta cgagaagata
    27601 aaggtaatcg tgcgtctacc aattcaaata cgatgtccac atatttcatt ttttcagaaa
    27661 cttctcgtcg ggcttttgcc atatgtcccg gaaaccattg gatggtcatt gttctctcca
    27721 ttcctttcat accggaatat tccccggctt tacttgtttt tttctttttc aatataaatt
    27781 cactttttta ttataaagaa attccatcta ttagttaagt gaaagtgaac cagtcctcat
    27841 tctatcacat cttcactttt ttgatgatgc aaatttttat tttggtttct atatatgaat
    27901 ctaaattttt gacagcgttt cctaaataag agatgataga cgaacaaaac agaaaggaga
    27961 cgaaacaaat gaatagtatg gtttttgtta attttcctgt tgctgatgtc aatcgttccg
    28021 ttgcttttta tgaaaagctg ggttttaaaa aaaatgaaga attttctact gaagaagctg
    28081 gttcaatggt atgggatgac actttttgga taatgcttct ctctcatgat ttttataaaa
    28141 aatttataaa agataaagaa atagctgata ataaaaaaac aagtggtgct ttgatttcgt
    28201 ttagtgttga aaatgcggat gaagtaaaaa aatttgctca aattgcaaaa gaaaatggtg
    28261 gtactttcca cgaagtagat atgggaatgc ctgaagaaga aatgttttca ttagaagtcc
    28321 aagatctaga cggaaataca ttagaacccg tatggatgaa gatgtaagca gataactaat
    28381 ctgacgtttt ttataacaaa aaaacaaagg cggatgatac gataagtatt ctccgcctct
    28441 atttttttta ttcgtacaat ctctttttta cagtttataa aagcagtctt ctcacccttt
    28501 ttttaattgt tagatgccag tgtatgtaaa tcaccaatgt gtcatgacac attggtgatt
    28561 ttatggtatc cttttattat taactgacaa aggagagaat attttgaaca ctttgattgc
    28621 aaaagacgtt tttagattgc ccgaaatgaa tgcaagattg ttgtcgacct ctgctctttt
    28681 attagccctt gatgtcatct tatacaagat agcgattggt cctgcttatt ttcaaatcac
    28741 attcggattt ttaagtatgg cgcttatggg ttatctatat ggaccgatct gggctggttt
    28801 gcttgaaatg ttgtcgaaca ctttaaattt cacgatattt ggttcaggaa cgtttcaagc
    28861 tgcttttctt atcacggctt tccttggtgg atttattaat ggcttatttt tatatcataa
    28921 aaagataaac ctgccttccg tcatcgctgc ccaattattg attatgatcc cagtcagcct
    28981 ttttatcaat tcttggctga tgtctgtttt gtttggtgca gatttcaaag taatttttct
    29041 aggtagattc atcaggaata tgatccaaat ccctattcaa ataatggttg tttattcatt
    29101 tatcaaaact ttagaggcta gaaaagtgtt taaacgagct gtttgatttt acgtactaag
    29161 gtagtaaact gattttggat taaacaataa agcgtgcagt ctcaacagac tgcacgcttt
    29221 attgtttctc actggatcca ttttatttca tcaagtggat aatagacaaa tcttgcttta
    29281 cctagaatat cagttttatt gatcgtgcca aacgaacgac tatcttttga aactcttcga
    29341 ttatctccaa gtacaaaata attatcttcc ggaagcttgg attgtcccgt tagctcttgt
    29401 agtgtaaagt ccgtcgtata ggatgcattt gcatgatctg atttcaggtt tttagttaga
    29461 taaggttcct taactacttt cccattgatc ttcaattgat cattttggta gctgacattt
    29521 tctcctggaa gaccgattac tcgtttgata taaatcgtgc catctgctaa ttgaaaaaca
    29581 acaatatcaa atcgtctgat ctccgaaaat ttttccatca caaccatatc accttgcttc
    29641 aacacgtttt ccattgaatt gccttccact ggtaccggga tgaataaaaa tccccgcaac
    29701 atgaacgcaa ggaatacaga aacaagtaag tatttgaata caagccagaa gcgattaata
    29761 tagcgttgtt tttttgtcaa tctctatcaa tccatccctc tttttttcat tctttcttta
    29821 ttataagaaa aatatcaaaa aaatgcgact agatagctga aataaaaata attctttcaa
    29881 ttaggctatt ggacaaaaaa cttttttgat cataaagtac aaaactatct cttatatgtc
    29941 atgattattt tctaaatatt tttcccatgc ttcgtcaaag atatccatgg acggcaaata
    30001 gtcgacattc agttccagat aattagaaat ttcttcgtag ctagagctgt gcttaggaaa
    30061 ttggatgtct ttaccggctt ctgtagcgaa aacagataaa gcatcatgtg tgccaccgcc
    30121 tcgcagtgtc attaaataat gaaaaaagct tcgattcacc cttcgttcct ccaattttct
    30181 tcgataaagg cagcccggcg tgcatggttt cttttaaaat tttcaggatg ctttttataa
    30241 tactcttgat ggtcttcttc tgctagataa aatggttggg ctggttcgat ttttgtaacg
    30301 attggctgtt cgaaacgtcc actttcagct aactgtttct tacttttttc agcaatgatc
    30361 cgctgttctt ctgtcaaata aaagatcacc gggcgataat tgtcaccgcg atcctcgaat
    30421 tgtccgaaag cgtcagttgg atcagtttgc tgccagtaaa gttctactaa ttgttcatat
    30481 gaaatcaatg ttggatcata gataatctcc actgcttctg tatgtccagt cgtttggctt
    30541 tttacttgtt cataagtcgg atctggtaca tgccctccag tatatcctga catcactgta
    30601 tggataccag gaagcgtgtc gaaaggctgg atcatacacc agaagcagcc tcctgcaaat
    30661 attgctcgtt ccattatgat tccccctcta atactactca tccgatgatt ttttattttc
    30721 ttttgtcttg ctttcagtac tgctggtgct agttttgttg gtatttgagt tgtttgaagc
    30781 atcagaggta tcttttggca aatatagact aaaccgaatg tcatcattta ctaagtcgat
    30841 tttatctgct ttaatataca tcccgttttg cattcggaat tgatccaacc taagcatgat
    30901 agtcagatca tctgtattga cttcgatcca atctggtaat ttatagtttc tcttgatcat
    30961 attcatcaca tctttgattg gcaaactcaa tgttccgata gaaagacttc tagcttttag
    31021 ttggacattt ccgttttcca tcacatacgg atcaaaatat aaatagaaat cgataggaaa
    31081 acctagtact tcgaaagtac cattgagtag tgcttcattt tccaaataaa atttatattc
    31141 aatatcacta tctttttgat actcactaag gaaaaagctg atgatttgat tgactttttc
    31201 tttatttgaa ttgatcgtta agacaggatc tccttgtctt tccgtaagag ctggtatttc
    31261 tgggagttct ggttcccgat tagcaaaaat acggctgcct aaaaatacgg tcgaaccaag
    31321 tactacccca agaaggataa ggaaggcgaa tttccagtaa tttgttttct ttgttttgtt
    31381 tgaagatacg tcagatcttg ttttcatgtt tattgatcat cctccttctc taaccattgg
    31441 ttttgtgtct cgatcagctg atctctcact gcatttgcca tcaattgata acctaaatta
    31501 tttggatgga aatgatcttc ttcatagagc acattatttt tgatgccatt tagattttct
    31561 gtcgtgctag ttgtttgatc tgttccttct tctgtgacac ctacttcctg attcaatcct
    31621 tgataaagca aatcattgat tgggataaag tagcagttcg gcattttttt tgtcaccgtt
    31681 tctgttcctt tgttccaatt gttaacaatt gtctgcatgt cagtgatctc aggaaagttc
    31741 aaataaaatg gattgtagat gcctaaaatg taaataggtg cggttttatt gagggatcga
    31801 aattcttcca atagttctgt gacattttcc tgatagtttt tcagtggctt tttaaaggaa
    31861 ttgaccgtta acccgaataa attattttgg ataactttca tcaaatcatt accgccaaca
    31921 gtcagtgtga taaaatcagc tgttttgata ttgtttcgaa tttcttcttt tgtttttact
    31981 cgctttaaga tctggtcact tcgttcacca tttacaccat agttttctgt ttcaaccgcg
    32041 gtcaaattat aacggtcttt tagatcattt gcgacaaggg gaacgaatcc tccttgcttg
    32101 gtttgatctc ctactccttc agtcagcgaa tctccgatag ctatgtagtg aagtttttct
    32161 tttttatttg gatcttctct cacagtagtt actggtttca ttagtgggcc agctttcggt
    32221 atagaagcag ctaaacctgc atagatgatg atcgcaatta ataatgggaa caaaacgagg
    32281 atcaaatgtc gtttcgttaa tttcattttt tcacctcttg tattcgattg gttctaatgt
    32341 tatcaaaaat tttatcaaaa aggtagtctt tatgaaaaaa gaaaacaatt attttcctaa
    32401 ttttataaag aaaaagagaa taagctgcaa gcctttcagg ctgagggctt atcctctttt
    32461 cgactaatct acataataca tgattgcaaa cgcgtcttta ccagtatgcg tagcgataac
    32521 cggattcgta tgcagtacag ggatatgcat gtccgggaat aattcttgca aaccctcttt
    32581 gaattcttgc gccaattctt ttgcatccgc atgtgaaata ccgatttgtc gcacatttgg
    32641 caattctttc agttcatttt tcaaattatt aaaccattta tcgaacgttt tctttcctcg
    32701 ccccttagtt acagggatta attcagaatg ggcgaaattc atcaccacgc gtatgttcaa
    32761 aacactagac agcaaaccag ttgttcggct gattcttcca ccttttacca agttatctag
    32821 tgtggatatt ccgatgtata attttgtatt gtcttgtact tttttgactt cttcaaggat
    32881 tttctctact gttttacctt cttttgctaa ttcagctgct cgaattacct gaaaagataa
    32941 tccttggtca gtggtatcac tgtcgataac cgttactttc gtttttgtta gattactggc
    33001 ttgtcttgct gcttctactg ttccactcaa gccttttgtc atatggatcg aaatcacttc
    33061 actgccgtct tctcctagct catcatacat cgagatgaat tctccaattg gtggttggct
    33121 tgttttgggc agattttttg ctttcgccat catttccata aatctttcgc cgtctagttg
    33181 gtcatcatcg ggatatactg ttccgtcgat catgatggat agcggcatga cacgaatgcc
    33241 taaagcatcg cgtacatttt tttccatcgt acatgaagaa tctgttacga tttttacatt
    33301 tgtcattatt ttctctctct ctttctttaa caagatgcct tattcatgtt aaactacatg
    33361 taagacaatt tctattttta gtataacaga caaataatga tttttcatta attacaccta
    33421 gtaaaggagc cgttttcatg gaaaaaacga aatttaatcg aacgtatgaa atattaaatg
    33481 aagtgtttaa tgcagtcacc catggaattg ggactggatt gagtatcgcg ggactagtgg
    33541 ttcttttagt aaaaggtgcc cacttgcatt cctccctcca tattgtctct tatgctatct
    33601 atggatcgat gatgattctt ttatttttaa cgtctacttt gtttcattca ttgattttta
    33661 caaaagcaaa aaaggtgttc caagtattcg atcatagttc gatttttctt ttgattgcag
    33721 gaagttatac tcctttttgt ttgctgagta tccgaggatg gctaggttgg actttatttg
    33781 tattaatctg gttgtttgcg attcttggca ttatatataa agcgttgacg ttgcataaac
    33841 gggagagagt atcaaaagta tctacgatca tctatatttt tatggggtgg ctctgtgtcg
    33901 tggctgctgt tcctctttat cactctcttg gaatgactgg tgttattttg atggtagcag
    33961 gcgggctttc ttacacgata ggcgcattct tttatagctt gaattctatc cgctatatgc
    34021 atgttgtttg gcatttgttt gttatgttag gtgcaggttt tatgtacttc tctgttttat
    34081 tctttactta ataaaaaaaa taaagctatg gatgggacag ctctaaataa cagctagtct
    34141 atccatagct tttttatatc gtcaattcgc ctgtcccgct ttttacagga ttctcattac
    34201 gctgatacgt ttcaaattga tgcggataac gatttttttc atccatttct ccttgactag
    34261 tattgatcag tgaccaatca gaccagtcaa caggtggaaa ataagcatct ccatcgaata
    34321 catgatggat gactgtacgg tataatatcg tacaaaatgg cagaaattct tgataaacag
    34381 ctgaccctcc agcgatgaaa aagataccgt ctgtttcttt ttccagagca agcacgtctt
    34441 ccacactatg catgacatgc acgccttctg ctttatagga agaatctctc gtcaaaacaa
    34501 tcgtctgacg attcggcaac ggacggctac ccatcccttc gaatgttttt cgtcccatca
    34561 ctagtgtatt tgcttctgtc atttgtttga agaatttcag atcatttggc aaacgccaag
    34621 gaagacggtc ttcttttcca atcaatccgt tttcatcctg tgcccaaatt gcagctaaca
    34681 ttttctcatc ctttctgatt ctaaacagcg ataggagctt tgatcgccgg atgtgggtca
    34741 tatccttcta attggatatc ttccatctca aaatcaaata ctgactgctt ttcctgattc
    34801 aaaactaaag tcggaaatgc gcgtatttct cggctcaatt gttctttcat ttgttcgata
    34861 tgattgatat aaagatgagc atctcctaat gtgtgaacaa attcgccaac cgctaaacct
    34921 gtttcatgtg caattaggtg agtcagcaac gcataacttg caatgttgaa cggaacgcct
    34981 agaaacacat ccccactgcg ttgatacaat tggcagctta gccgtccctc ttgaacataa
    35041 aattgaaaca tcgtatgaca aggaggcaaa gccatgctag gaacatcttc cggattccat
    35101 gcagaaacga tcaatcttct agaatcagga gtctttttga ttgcttcgat cacttgtttg
    35161 atttgatcga taaagccacc gtcttttgtt tcccagtgac gccattgata gccgtagatg
    35221 tgtccaagat cgccgtatgt ttcagcaaag gaatcatcgg ttaggatctt ctcgcaaaaa
    35281 agcttgctct gctttttata ttcttcattg aattcaggat ctgtcaaaca tctatggcca
    35341 aaatcagtca tatctggtcc attatagtct ggacttttga tgtagcgttc aaatgcccat
    35401 tcatcccaaa tatggttttt attttgtaat agatagcgga tattcgtatc tccttttaaa
    35461 aaccaaagca attcgctttt gatcaatcca aaaggtactc gtttcgttgt taacaaagga
    35521 aacccttttt gcagatcaaa ccgcatttgg tatccgaata agcttaatgt gcctgtgcct
    35581 gttctgtctt ctttacgatg cccttcttcc aacaattttc ttcctaagtc aagatacgct
    35641 tgttccatcc tttttcctcc taatcttcta cccattcact caagtattcc caccgtgcca
    35701 ttttttcttc aagttgtgct tctgtttcag atacgtcgtt ttgcaattct tgtaatcgag
    35761 tgaaattatc tccttgatga ttcatctctt cttggagcaa tgagattttt tcttcaagtt
    35821 ctgcaatctc atcttcaatc gtttcccatt ctttttgttc catgtaagat aatttcttct
    35881 tttcagcagg ttccttgctc tgtatttttg gtttcgcttt ttcagcaggc tgctgggtct
    35941 ctttttgctt cagtaaataa ctggacatgt ttccgtaata aagttcttgt tttccgtttc
    36001 cttggaatac taataactta tctgctacct tgtccaagaa ataacggtca tgggaaacag
    36061 tgatcacagc acctggaaaa cttctaaaat aatcttccaa aatcgtcaat gttgctatgt
    36121 ccaaatcatt ggtcggttca tccaataata aaacattagg ttgctgaatc agcagtttca
    36181 acaaaaataa ccggcgtttt tctccgcctg aaagtttgcc tatcagtgtc ccatgcataa
    36241 atcttggaaa taaaaatcgt tcaagtaatt ctgctactcc gatttgactg ccatctgctg
    36301 tttttgcttc ttcagcagct tcttgtaagt aagcaatcat ccgtttatct ggtgccattt
    36361 cttcattttc ttgtgtataa tacgcaagat gaaccgtttc accgatagac attgtaccgc
    36421 tatccagggg aattctgcca gctagaatat taagcaatgt cgattttccc gcaccatttt
    36481 taccagtaat acctagtctt tcccgagatt gaatcaataa atctaaatgt tctagcagtg
    36541 tttggtcatt tatacggtaa ctgccatctt tgatttccag tacttttttc cctaaacgtt
    36601 gtgtcgctag gttcagctct aaatcatctt cttggtttac ttggtacaag ttctccttta
    36661 gatcttcgaa acggttgatc cgtgcttgct gcttggtgcc acgtgcctgt acgccagccc
    36721 tcatccaagc taattcctgt ttataaagcc gcttgcgctt ttcttcttgt tctacttcta
    36781 cacgatcacg ttctgctttt tctaagacgt aagcttcata atttccttta tactcgtata
    36841 attttccaaa tgaaagttcg aagattcggt ttgctactct atctagaaaa taacgatcgt
    36901 gggtaaccat caatagtgcg ccacggtatt gtttcaaata gttttccaac cactcgatcg
    36961 cttcataatc taaatggttt gttggttcgt ctagtaatag taaatcgggt tcatcaatca
    37021 acacttgcgc cagactaact cgttttttct gaccacctga taaagtactg atttttttat
    37081 ctaattcact gattcctaat ttttgcaaaa taatctttgc gttggtatct gtagtccaag
    37141 catcttcttt attcatttgt tcttctgctt tagcataacg tttttgcaca tcagggtctt
    37201 ctccgttttc ccctagttcg atcaatgctt cctcatatgc tcgaacagtt tggatcaagg
    37261 ggctgtttcc ttgaaagact gcttggagaa cagttaattc atcggaaaat tcagctgctt
    37321 gagaaagata accaatacgg taatcagttg gataaaacac tgtttgccga tcaccgtcgc
    37381 tgctatcgat accggcaata atatttaaga gacttgtttt acccgtcccg ttcgtcccaa
    37441 tcaacccgat acggtctttt tcgtggacca aaaaagaaat ctggtcaaac aaatcttttt
    37501 caccataagt ttttttgagg tcagttactt ttaattcttt caacatgttc cctccttatc
    37561 ttggatattg tatcataaaa atagtgaact tcaggaaaat ttttttggta tttgttcttt
    37621 ttgtgttctc aaaaaaagaa caggaccgat tcgatcctgt tctgatatgt tttgtttttt
    37681 ataaaacttg aaaattttta cctttttatt ttattggact cgtttttttt gactttgctc
    37741 gaaacgcaaa tcggaaagaa aagttatcag atggtttgtt catcgtataa gattctaaca
    37801 aattgatatt cctgcgatag ctgttcgcag aaaacgtcgt gattttttca gcaacttcgt
    37861 attcatcaat gatttttctt tcaagataat aacctcttag catttttttc gtaaacagac
    37921 tatcttgctg gatcatccac gaagaaatca aattccccga gttcattttt attccttcaa
    37981 gtttgcgttg ctggataaaa aattgaacca tcgtttcatc ataaatatca gtcaagttat
    38041 ctaaactttc aataatcaac tgagtatttt tttgatatgt ctctctgatt tcttggatat
    38101 cttcatcact aataaatgtc tgacgatcag catatcttct ttgccaaaac attttcggat
    38161 ggagaacgat tcgcattaac ctacggacaa caatgaacca aaagccgata aaagacaaaa
    38221 tctggcttgt gatagaatgt tcgaatcgag aaagaaaacg ggagtaaaaa cgataaccat
    38281 tagaagaaag cttgcccgaa cgataacttt catccaatcc atcccgttcg atcgacaaaa
    38341 tcagtgcttg tatttcttgt acttcttgct tttcatcatc ggttaaatct tccaagtaca
    38401 gatcacgtat ccgttcttga taattttcta tcactgcttc agtggctaaa aattcttttg
    38461 tattacgatc aatttccttt atttcttttc gcaaaacttc aacgacctct tctaaaatca
    38521 tcaaagcatt caaatccgtg cttttcgctt cctctgtttc cgtcagcata ggcaagacaa
    38581 tgatccctat gaccaaagtc actaagatga cacccgccgt cagaaacaaa agcaaagacc
    38641 gctggtaaaa catcatatta ttgattgaaa atggcaaaat aaaaatcgta gccaaactga
    38701 ctgttccctt tacaccgcca aatgttaaga tcaagatctc gttcaactgt tttttgaact
    38761 ttttactgcc atctttgaat acataaaaaa gactgataga aatgaatctg atcacaaaaa
    38821 gcatgacaga gattaatacg ataatcgcta ataaaagacc gtttggatat aaaccgtctc
    38881 cccatactgg cgagaacact tgcgtcaatt cgattcctaa aaatataaat actaatgcat
    38941 tcagtgtaaa agcaatagtt gtccatgtac tgtgggacaa gctcgacaat tctgcatcaa
    39001 acacagagat tttcctaaaa ccagaagctt ggagaatacc tgctgccact gcagcaatga
    39061 ttccagatac atcaaatgcc tctgccaata cataggctag aaaaggaagc aaaagttcga
    39121 tcagcagata ccctgtgaca tcttgtgctg atgctttttc gatcaaatga attatttttt
    39181 gtttgaacca gacaagcaaa aagccgatca aagctccccc aatactagaa actactagac
    39241 tcatccccgc gtttactgct gaaaaagatc cggtgatcag cgcaccaaga gcaaactgga
    39301 aggcagtaac accagatgca tcattcaaaa gaccttctcc ttccaaaata tgcatcgcct
    39361 ttttagggat attcactcgt ccagaaagag aactgactgc taccgcatct gtcggaccta
    39421 acgctgctcc aaaagcaaag caggcagcaa gtgggacact tggcaacagg aatgataacg
    39481 tcgcacctac cccgacaagg gtcaaaatga ctcctccaaa tgccaagaac aaaattgtcc
    39541 cgaaattttt gagaatcgaa gaaatatctg ctttttctcc ttctctaaat aacaatggtg
    39601 caataatcat aactaagaac aattcaggtt caaaatcgat tgattgtccc cactctgtca
    39661 gacctaatac cactccaagg aaaatttgga tcagtggagc tggaatcatt ggcaaaatgc
    39721 ggctagctat gttcgataag gtgatcgtta ctgcaaatac aataactaac tcagcaaatt
    39781 ccatcgtcca tcccctttat tttttatttt gtgtaagcat ttttaaaaat tgttcttttt
    39841 tctttaaaat tttggtttcg actacttcaa cctgtgtttg gttcccctct aattcacact
    39901 gtacacgttt tgactccaaa cgaagcagat catgtttcag acgttccaac tgacgataca
    39961 tcaatatatt tcttttacgc aacttacaaa gtatttgacg gcggtcatcc atcgaaaggg
    40021 cgccatagcg atcatgcaac agtttttttt gttgttcaaa actctctctc attttccaga
    40081 tctcctatac acaaacttcc atcattatag caaagttctt tttggatgaa aaatatttca
    40141 ttgtttcatc gtttattgct agttagaaat ttccataaat ttttcaacgc ctcattctat
    40201 tccaaatagt atcagatatc aagtaaaact taagaaagat aaaagtttct gacaaaagga
    40261 tgtttacttt cccattcctg cctttcttgt tcttttatca caacaaaaaa atggggctgc
    40321 gacaaaaatc ttgtcacagt cccttattct gaataaacgg tgtggaagag acagcctatc
    40381 agtagtaata agacacatct ctttcacagc ctcatttttg cgtaaaaatc gatttattcg
    40441 aaaaattccc cgtatacatc ttctacacgt tgatctggat tgatcacgat atacaagtta
    40501 cctgtttttt cgctgatttt tgttgattga tattgattgt ctaatccttc tgttccttta
    40561 tctagatatg ggaagtacac aagatcaggt gtgccatttc ggtaaaggat ttccattcgc
    40621 tcgatatctt cgtatttcaa tgcgcgatta aacatgccca tttccagtcc gcctaggttg
    40681 atatcatgtg tcgcaactgc gtccccttca tggaagattt cgattttaaa tccagcacac
    40741 ggatggattt caacaaattc actgccattg attcgtccaa aacttgttgt gatttgtttg
    40801 atccaaagat cgccgatatg acggcggttg atcgtccagg tttctccatt tctaaaataa
    40861 aattttagcg ctgtcatttc tttactcatt aaaaagactc ctttatgatg taatttattc
    40921 ttgtactacc tcagtttagc acaaatttat gtaagtggtc acatcttatg ttttttcttc
    40981 taatgacgta tctgcccact ttaagtagcc aacaaagctg agcagataca gtctagtgtt
    41041 ttttaaatca atttttcttt cgataaaaaa tccaaaacct gttttttatc attttttatt
    41101 ctttgttcta cgacggcttt ttcagctaat tgcaaagctt cactaaccca cttaccaggt
    41161 ttttttccag tttcttctag caagatttta ccatctactg ctaattcgct taatgacttg
    41221 ataggtaaac gatcatagga ttctcctacg gcatccatct gaggtgtttc gtcaaaatag
    41281 atcatcaatt cttctacttg cagtgcatgt tttttgccta agaagtacaa ttcgaatggt
    41341 tccaaagctc cagtttctcg ttgtcgtagt ccttggacaa gtgcttgaac gtctttaatc
    41401 atttggttag aacacttcca cgatttcaaa aaggaacgaa tctcattttc ttttagatcc
    41461 agttggctga tcaataatgc ccatgcttgg ctctcttctt tcaatgggac ggatggtaat
    41521 tcagcaaaac gtaaaagtgc ttcgccttct tctttcaaac cgggacagca aatgtagcac
    41581 tctgtttcaa taaatgcatg gattcccgcg gcccgttcat ttcccaagag catcttgatg
    41641 aattccacat ttatacgttc tacagatatt ttacctaata gctcgtggtt ttctttgatg
    41701 gcgtagaagg tttcttcctc taatttgaac cctagttgac tgacaaaacg caacccgcgc
    41761 atcattcgta aggcatcttc atggaaccgc tcatgaggat tgcctacagc tcgcaagatc
    41821 tgttcttcta gatcttgcag accatcgaac aaatcgatga tttctccatc ttctttcaaa
    41881 gcaaacgcat tgatcgtaaa atctcttctt ttcaaatctt ctgccaacga acgaacgaat
    41941 tcgacatgat ctggtctacg gtagtcctga taagttgatt ccgtccgaaa tgtggtgatc
    42001 tcatattgtt catcattttc taataccaac acagttccat gttcgatccc aatatctatc
    42061 gtttttggaa aaagctgttt gatttcttct ggaaatgcgc ttgttgcgat atccacatca
    42121 tggattggct ggttcagcaa gatatcacga acacttccac ctacaaaata agcttcatat
    42181 cctgcattct ctaatttttt cagaactgga attgcctttt ggtattccag aggtaattgt
    42241 tttaatttca tttttccaac ctttcctgcg tgtttcttgt cctgagataa agactcagtt
    42301 gcatggtgac tgtttgacaa gtccgtttca gagtcttcaa ggccaggacc acttcatctt
    42361 gtttactcgt ccttacgctc aaagcgatta tggtctcttt gattgaattt ttccatgttt
    42421 ttttcaaaaa cttcagttaa gtcgatattc aatgaattag ccatgatcat cgtaacgaat
    42481 aaaacatcac caagttcttc tgctaccgag ttaactggtt cagaagcctt tttgcttttt
    42541 tctccataag tgtggttgac ttctcttgcc aattcaccta cttcttcagt taatcgagcc
    42601 atctgagcta atggagagaa ataccccacc ttgaattgct ggatatattc atccacttcc
    42661 tgctgcatac tgtataaaga acgcttttta tccatctttt tccctccaaa actatcttac
    42721 caaaacttta acgcaaatcc tagataagag caattgagaa aatcgaattt ccatgctaca
    42781 tttaggaagg aatttctaaa tggaaattct gtgaaaatac ataattgaaa gctggaattc
    42841 atatggtcaa acgaaaaaca gtaaaagaag ttctttttat cattatagga acaagtattt
    42901 atgcatttgg tcttgtttac ttgaacatcg ctaatcattt agcagaaggg ggagtctcag
    42961 ggatcacctt gatcttaaga gctttatttg gtattgatcc agcttatacg actttattaa
    43021 tcaacatccc attgatttta ctaggaggaa agatcctcgg taaacgttcc ttggcctata
    43081 ctgttctagg tacactttct ttgtcattct ttttatggat ctggcaaagg gttccactag
    43141 aaatcaattt acagcatgat ctactgatcg tttctctact tgcgggttta gttgcaggtg
    43201 taggaagcgg gatcgtctac cgcatgggtg gaacaacagg cggcagtgat attatcgctc
    43261 ggattttaga acaaaattac ggcatcacta tggggcgttc cctattggca tttgatatca
    43321 tcgtcttact tgcttcatta acctatatcg acttgaaacg tatgatgtat acgttgattg
    43381 tttcgtatgt tttcagtcgt gtgattgatt cgatcttaga tggcggatat tctgcaaaag
    43441 gtctacttgt cgtctccaac aaaagcgaag agattgcacc actactgatg accggtctgc
    43501 aaagaggtgt gactttcctt tctggagaag gcgcattctc tggtaattca aaaaaaatca
    43561 tctatatggt cgttagctct agtgaattaa ctgaagctaa gaggatcgtc cacgagattg
    43621 acgaaaaagc tttcctttca atcatcaatg tgcatgaagt ggaagggcaa ggctttactt
    43681 atttgaagcc acagacaaga ttactgaaaa aactataaga aaaaagacaa agataggcta
    43741 tgaggaaaga ttccacatcc agctgacctt tgtctttttt agtactatac tatttttaac
    43801 taattgttat gttcacttac ccggttactt ttcttttgtg tctgcaaaag gatctttcgg
    43861 ttaacttcat cagataattt caaaaaagca tccctatctc catcttctag tgcttgatcg
    43921 atttgagcat aaagcatttt tagttttgcc tcttcttctt tttcttgaaa atatcgttca
    43981 attaattcag tatcttcttc actgactgaa gaatcccaag aagaaaatgg attgtcttct
    44041 aagatagata gatattctct tgtctgccaa gcattttcga atatacattc cacatataaa
    44101 ggctttttcc aattcaaacg gatttcatga aaaatctggt ctgtgtccgt aaattctttt
    44161 ccctgcaaaa acaatttcat gggttcccct tcaacagata gatcactgat ctgcagtcct
    44221 cgatccgcaa aattcgcccc ttcaacaaag tggacattgc ttaaaatcgc ttcatgattg
    44281 gcaagataat tcaagatcca aaaaacttct cttcggctaa aagatacatg attgaccatc
    44341 cacgttaaaa aattcttctt ttcccgtaca tcaattagca tttttctcac ctctctgtta
    44401 ggtcatctaa taatgacagt gcctccatat ctcctggttc aagtgttaaa taataagtca
    44461 ataattcttg cgctcttttc agctgccctt cttctcttaa gaaaaaggca tactctttca
    44521 agaaatctgg ttcatgtgat agttcatgat aagcctgttc atagtgtaca gctgcaacgg
    44581 taaagtcttc taattcatta taagcatggg ctaggttcca ttctgcataa ggattagcag
    44641 tttcttccat ctgattgatc acttgtatca catcttcata tctttcatca tccaagtaaa
    44701 gattacttaa agtaagtaat gtttcatctt gtttgtctcc tacttctaaa gctttcagta
    44761 aaagttcttc tgctcgctgt ctatcatgca gacggaaagc attttccgag gccaggtgat
    44821 aaagttcgac ttggtaagga ttttctttga ttccttcttc taacactgtt tgtgcttctt
    44881 caatcatttc ttcttcttga agagcttgtc ctagatatag atataacgat tgataatgcg
    44941 gattaacttc tcgaagttct tccagatagt tgattgcctg ctgattttct ttcaattgaa
    45001 gattcgtaaa agctagctgg aacagtcgat catctgtcct ttcttctttc agtgcttctt
    45061 ctaaaggtac gatagctgct tcgaattctc cttgcatact taaggattgt cctaaacgtt
    45121 cctgcatcga gattcctgaa atttcattta tcccgcttgc caacaatgtt tcataaacca
    45181 ctgctgcctc tttgaaacga tcaactgaaa aatacaattc agctagcgca aactggatca
    45241 atggttcatc aggaagcaac ccagctgctt ctttcaattt tgcttcactc acttcaggga
    45301 ttccgataac ttggtacaaa tcagctatcg ccaataagct ttgcggatag taatcacttt
    45361 gcttatccac tttttccagg tattcaaaag ctaagtcgat ctcattatct tcgattgcaa
    45421 tttctgctaa cgggatgttc agtccgtcat tttctgggta ttggttgatc agttgttcaa
    45481 aaatctgttt tgcttcgatc aaaaagccaa tagccagcaa ttcttcgcct agttcagcta
    45541 atatatctgc tgggtcttct tttaatgctt tttctaaaaa gatttgtgct tgtgacaagt
    45601 cttcatctga taaagcttgc aacatttttt cgctatttgt attcatttca attccctctt
    45661 atctcactga cgatttgttg aaataccgtc attgttctca ataattcttt ttcgtttgga
    45721 tgttggtatc cgtctattat acctattttt tctaaaacaa gtattttttt gcttttttct
    45781 gccaaaaaaa gaactttttc caaatactcc atctttgaaa tctgttccag ccagtggatt
    45841 ggatagccaa gcaagtccag ccacacaaaa aagtttttta gttggaaatc aaaaggatat
    45901 gcttggagat tccacacgaa atgaaacatc attcctaaaa attttttcat actagcagaa
    45961 agtagatggc cattttcggt cagataaaaa gcttgttcaa acagtttacc ataatttgac
    46021 aggttttctg cctctaattg ataaaaatag atcatttctt cgatcatccc ggcaaacggc
    46081 cgagtcgtta attgcttttt atttggatag tttttataca gattttgcaa aaaacgatga
    46141 tcacaaatca ttccgcaaca gataaaagtc aaaaagtcaa tctgctttcc gtccacctgc
    46201 cgctcgctga ttgtttgatc ataaacgatg cgttctggca gattgatggt ttgcagcact
    46261 acacgatttg gtagctgcaa aatcgtccgc tgcggtgtta atgctcggct tagagaacgg
    46321 atcgatacag ggatcatcca tagtgatgaa tcaagggttg tatgtttttg aaaaaaacct
    46381 gccagatcca tgatcccttc atttccaaat ccgatgataa acatggattg attttcggga
    46441 tagcgtttga cgaaatcaag caggttcttt aattctgtta aatgattgca ttgagtgttg
    46501 gcacaaatat accagtcatt gtttgcttga tttgcaaata acgggttgat cttatctgca
    46561 aacaaatcat aatagcgctg attcgttaaa aataagattg gctgatcaat ggaaagttct
    46621 cttagctgac tgactagcgt ttctccgtaa aacactttcg tcaacgcatc ttctacttga
    46681 taatcaagtt ccatacgcat ccctcctctt cttattttta ttttaccatt agtaagcaaa
    46741 ttctagaaaa gataagagca aagctcacct cataacttgc aaataaataa aaattaaata
    46801 aaatacatgt gttttctatg tatgacatac ggattcggaa tctctgtctc ttatttattc
    46861 cttttctgct aggaaataaa aagaaaagca cttgtagccc tagagccaca agcgcttttt
    46921 caactgtctt atttaacagc gtcttttaat gctttacctg gtttgaatgc aggtactttg
    46981 ctagctggaa tttcgatttc ttcaccagtt tgtgggttac gacctttgcg agctgcgcgt
    47041 tcgcgaactt caaagttacc aaaaccgatt aattgaactt tttcgccgtt agctaaagca
    47101 tcttgaatag ttgaaaatac agcatctact gctgcagttg catctttttt agttaaatca
    47161 gtagctgaag caactttttc gattaattct gctttgtttg ccatggatag attcacctcc
    47221 tccacaagag atatgataga aatatcattt agttaaaact ttctgagtgg tccagaagtt
    47281 taaaaagaaa tattgattaa cttcaatatt ctgttatcac gatatcatat gaaccgctta
    47341 atagcaaggt ttttaccaat tttcacatgc tttttttagt catagaaacg taacaaacga
    47401 aactgtcttt ttcttttgaa aaaaaaacgt cgatatggta aaatgcctat tttctcctac
    47461 gagggataat tcggatggac gtcccttcaa aagtaaatgc ttttctgatt tgattttcta
    47521 agaaacgttc ataagaaaaa tgcatcaatt cctcttcatt gacaaaaacg acaaatgtag
    47581 gtggtttgac agcgacttgt gtagcataaa aaatcttcag gcgttttcct ttatctgttg
    47641 gtgttggatt gattgctaca gcatccataa tgatatcatt caacacagcc gaagagatac
    47701 gaagattctg gttcatactt acttgttcga tcatttcagg cagacgttcc aaccgttgtt
    47761 tagtcactgc agaaacaaaa acgattggag cgtaatcaag ataccggaat tcatcacgaa
    47821 tctcttgttc gaaatcacgc attgtattgg tttctttctt tacaagatcc catttattca
    47881 cgacgataat aattccacga ccagcttcat gggcgtaacc cgctactcgc ttgtcttgtt
    47941 cccgaatccc ttcttcagca ttcagtacca tcaaaacgat atcagaacgg tcaatggcac
    48001 gcattgcacg catcacgctg tatttttcag tattttcgta tacttttccg cgtttacgca
    48061 taccagctgt atctatcatt aagaatttct gaccactttc agaaacgaag tgggtgtcga
    48121 ttgcgtctcg ggtcgttcct tcaatatccg aaacaattac acgttcttct cctaaaatcg
    48181 cattgatcaa agaggattta ccaacatttg ggcgaccaat caaactaaac ttaatcgtgt
    48241 cgtcgtcctc ttcttcagtc tcttcagaga aatacttcac tgcttcatct aaaatatcac
    48301 caatccctag tccatggctt cctgaaacag gataaggatc gcctagccct aaggaataaa
    48361 attcatagat atcgtttctc atttctggat tatctacttt attgactgct aaaatcactg
    48421 gtttattact tctgtataaa attttcgcaa ccatctcatc tgcgtctgtc acgccttcgc
    48481 gtccgctgac tacacaaatg attacatctg cttcttcaat cgcgatttct gcttgatgct
    48541 tgatctgatc cataaaaggt tcatcgccaa gatcaattcc gcctgtgtcg atcacgctga
    48601 attctcgacc taaccattca ccttttgcat aaatacgatc acgagttact ccaggagtat
    48661 cttcgacaat cgagatacgc tcaccagcga tgcggttaaa aatcgtagac ttaccgacgt
    48721 tcgggcggcc aacgattgca attgttggat ttgccatatt atttcctcct cacaagtttc
    48781 caatctcact tagtttaacg aatgcattgc caactttcaa gcatagattg tcaattaaac
    48841 gaagtatttt tattccttat tgaaatacta atcgcttttc aaaagaaaaa ctgagacaaa
    48901 agcagctgct ttcatctcag tcacagatac aaaatcaatt atttttcaga atcatcggtt
    48961 gctttttctt ctacttcttc tttcaacgca tcacctaaaa tgtctcccat agtaaatcca
    49021 gtattttctt ctggtaattc ataagactca acattttttg gttcttcttc tgaagctggt
    49081 ttttcttcta aagctttgat actcaatgca atacgatgtt cttctggatg gatctctaat
    49141 actttcactt tcacttcgtc accttcatga agcacttcat gtggtgtcgc aatatgttta
    49201 tgtgaaattt gagagatatg gactagccct tctactccag ggaacacttc aacaaaggca
    49261 ccgaagcttg tcaaacgttt aactgttccg tctaatactg tgccaactgg agcttttgta
    49321 tcgatttctg accaaggtcc aggctgtgtg tctttgattg acaaggaaac acgttcttgt
    49381 tcaggattga tagacaacac tttgacattt acatcatcat tgacagccaa tacatcactt
    49441 ggttttgcta catgactatg tgaaatctct gagacatgga ctagaccgtc aattccgcct
    49501 aggtcgacaa atgcgccaaa atcagtaaga cgtgcaacac gtccactgag aacatctccc
    49561 tcatggatag ttgaaagaat ttcttttttc ttttcttctc tttcgttttc cactaccgct
    49621 ttatgcgata agatcaaacg attttctgat ggttcgattt cgatgatttt aaagctcaat
    49681 gttttgcctt tatagtctga aaagtctgca acaaaatgat cttccaccat tgatgcaggg
    49741 acaaaaccac gtacaccgac gtcaacgact aaaccgcctt tgacaacatt tgtaacaggt
    49801 gcttcgatga ccttgccctc ttggaaatct ctttcgatat cttcccaaac ttttttagca
    49861 tctaaacggc gttttgaaag tagatagctg ccgttttctt tatctttgcc gatcgtactg
    49921 ataacgacta aatctaatac atcaccgact tttactactt cgctgatatc ttctaccggc
    49981 aaagttgata attcttttgc cggaacgact ccttcaactc cagccccttc gattccgaca
    50041 atcacttgtt tgtcttcaat gactaaaact tcgcccttaa caacatcgcc aacttttact
    50101 tcttgtacgc ttttcattgc gtcttccatt gactggttgt tctcttgatt ttgatcaaat
    50161 tctgtcataa cacttgtcct cctaaccaac attctgccgt aagtacggta ctgtttttag
    50221 tttaattgat tattcaaaaa aaataaagcg atttcgttcg ttttccttga aaaaacaatt
    50281 gtttttcatt ttttttctta atttaaaaaa gaagataacc ttttttcaaa acaacagctt
    50341 ttattgctgc aacgacttct ggaatcgatt tgccagtcgt atcgatacga acagcatcct
    50401 ctgcttgctt cagcggagag acgtcccttg ttgaatcata atggtctctt tcctgtatct
    50461 ctttcgtcag tgtttcaaga tcagtcggaa ttcctttttc ttggttctct ttgaaacgtc
    50521 tttctgcacg ctcacttacg cttgctacta aaaagatttt cacttctgca ttcggtaata
    50581 cagctgtccc gatgtctctt ccgtccatga caacgccacc gcgttcccct atttttcgtt
    50641 ggacagcaac taattcttct ctgacttttc catgtgcaga gacttcagaa acagcttttg
    50701 tgacatctgg ttgacggatt tctaaagtca catcttttga tgctatgaat acatgctgtc
    50761 catcttcttg ttgcgaaaaa gagataggat actttttgat cagcgaaact agcccttctt
    50821 catctgaaaa agatacattg ttcgtaatag ctaaataagt tactgcgcga tacatggcac
    50881 cggtatctgt ataaatataa ttcaattctt ttgctaatat cttggcaacg gtacttttcc
    50941 cagatgaagc aggcccgtcg attgcaatac tgatttgtgt catgatataa ctcctttttc
    51001 tcagaaaaaa agccgcaaag cgcggctatt attatttaat tcttaattct tgaccagggt
    51061 aaagcataaa gttgtttgga tctaagccat tcaattcaaa caattgatca gtggtgatcc
    51121 ctgcacgctc agccacttgt tttggacctt cgcctgcttg aacagtcgtt gttgaaccgg
    51181 ctgcagctga tgaagaaggt gttgtttctg ctgcattgct gcttgaatcc cctgcttgat
    51241 aagttgcctc acttgaggaa gtcggtgttg tctctgctgc aatactgctt tctgacgtta
    51301 cacctgtatc ttgagacaca gtagattctt ccgcgattgt actagattct actgttgaag
    51361 tctcagttga ctcctctttt gttgtacttg tagaactttc tactactgat gtcgaagttt
    51421 cagaagaagt tgctgctgtt gcattgttgc ttgatccatt tctgatccag aaataagcac
    51481 ctgctggaat agcgatacat aagaccagta aaatcaaaaa tagcgaaaga aataatgtat
    51541 ttcctttctt ttgttgtctc tgagaacttc ttgatgaaac ttcatcatct gtatcgtaga
    51601 ttggttgttc ccatggttct tgtgtttcgt tattttctgt agattgatgt ctatcttttc
    51661 tgctcactgt tttacctcct aaactctatc gtgtgtatta taccatagga aaaagtgtct
    51721 tgtcctaaaa aatcaatgtt ccatgttttt tttaaataaa tttagtaaaa tcgttcccca
    51781 atgaagttgt tcagtcttag aaaaaagctt cctctttggc agaagttctg cttttgctcc
    51841 atcaatatca caacaattct gcggcttttc ggagagtttt tcgccaaaat aagctaagat
    51901 gaattttctg cggcagtttt cttcattaat atagcgaagc atctgctgca ggcggaattc
    51961 tttttctttt tcctgacgtt tgagccgttc cacccaattt tctggttttt cagactgctg
    52021 gatcagctcc atccattttt tttgcagctc atcaaaggga gcttgctctg tggcatattc
    52081 caaataaagc tcaaaacttt gtcgctgttc tctagaaagt tgattaaaga aataatggat
    52141 acgttcatcc ccactttgat aaaaaagaat tgctgcactt tcttcctgat ctctgcctgc
    52201 tcgaccgatt tcttgtacat agttttctag actgtctggc aaatcataat ggaccacata
    52261 acggatatca gatttatcga tccccatacc aaatgcattc gtagcaatga gaaactgcag
    52321 ctgatttttt acaaactgct gttgaagttg tcttctttga gctgcatcaa gaccaccgtg
    52381 atagtatcca actgtaaaac gttccctgaa taaatgatac aatcgttcga cttctttttt
    52441 tgttgcacaa taaatgattg ccgctccttg tgctctttcc atgaagtgtt caagttcttg
    52501 ttctttttgc tgcgttttcc gaacaaaaag cgagatattt tgccgattga ctgattgtct
    52561 gatctctttt ggtggtcgat caaatagtac atgacgtata tctcttgcta ctaaatctgt
    52621 tgctgtcgcc gttagtgcca gtgtgaccgg gtttcctaaa agctttcgga tttttcctaa
    52681 ctgttgatat tctggacgga aatcaactcc ccattgagac acgcaatgag cctcatctac
    52741 tacatataac gcaatatttt gttttttcag atgctctaaa agagaaggat tagtcaacat
    52801 ttcgggactc aaaaacaaaa atttatattg cgatagatga cggaggacgt atcttctttc
    52861 agattgcgaa agtaaactat tgaaagcagc tactcgtttc tcccctcgtt tttgtaattg
    52921 cgtcacttga tcttccatta gagaaagcag cggtgacacg atgatgacca gaccttccat
    52981 taaatacccc gtcaattgat agcaaaggct ttttcccgtt cctgtaggca aaatagcgag
    53041 agtatcttct ccatcaagca acgcctgaat aatttcttct tggccgggac gaaatgaatc
    53101 aaatccaaaa tattttttta attcatttat taacattctg tatcgcttcc tttctcaata
    53161 gatagatttg atacaaacga aattctccat aatctaattg tccatctaca ttccattcgc
    53221 taaagcgcca ctctcgcacg gaatccttat ttggttccaa acgttcgatt gtttctgcag
    53281 agagaatcca ctcgtatgga aaatcatcaa aaaacaaggc ccactcaata agatgatctg
    53341 ttactgttcc tctttttaaa tgacggattg ccatgatctg gtcaattgtc tgaccattca
    53401 taaacatctg cttggtgatc atcatgcttt gattgaaatt ttgctgtaat aatgaatcga
    53461 tcaaagcgtg ccaaagcgaa tctggccgtt tttcgatttg tgctaacaaa aggtggatac
    53521 atctgctttg ttgcagataa accgctgact catcattgtt ttttgccagc tgataaggaa
    53581 gcagccctgt tcgctcattt ccagataatt ggttagctaa aaaatctgct gcttcttctg
    53641 gtatctccga aaacagctgc accaaactct catacgcagt atcaatcaaa atttcacgtg
    53701 gcaattggct ttcactaagc cattttttta gttggaaagt ataaaaagga cttgtctctg
    53761 ctggaagata gtcttgaata cccgttgcca gattagaaat tacttgaaca gcaaatttaa
    53821 tgagccgcca actagtttcc cctgttctgc catagcggtc aaaacgcaaa ccagtatgtt
    53881 ctatttgatg ttcggacaac atatcagccc ctgcaggcgt tagctttgct tcattttcat
    53941 ttatttcgat ccaaccttgc tgcgcaattt tttgcaaaat ttgataaaac ttatcctgct
    54001 tcaattctgg aaaactgtta tggataaaca aaagttcgtg ggtaaatcca taaataagta
    54061 ctgaagtcgt tcgttttccc acaaggagtt ggtaaagaga actaatccgc agcttgtgtc
    54121 ctgatgaaaa tagcgataaa ataaaaacaa tcatattatt ctccttaagt taggatggtt
    54181 agaaatgtca ctactatgta aacttgtacc tgaacgctgt attgcatgcg gtctttgtca
    54241 aatcgaagcg ccagatattt tcgattatga tgaagaagga atcgttttat ttgcccaaga
    54301 accagaggct catcaacagt tcgtgatgcc ggaagaagaa acatatgtaa aaaaagcgta
    54361 tcaaaaatgt ccagttcgag cgattttatt agaaaataaa atataaatat aaacgaaact
    54421 ttaaaaacgt acactaagtt ctctaaactt gaaaataagc cgggatctgt ttctcttgtt
    54481 ccgtgaaatc ccgacttatt ttgaaagatt catttgctat ctatagttaa ttgactagtt
    54541 ttttcacgga ccctatagga cccatttata ttatttcaac tttttcagcc agttttccaa
    54601 tgtattgacg atcacagttt gctggtctgc gttagaaatt tctgcctctc catctccttt
    54661 ttgctcacca tagctgccaa aacctccatg atttccgcca ttgattgata catactctgt
    54721 tctttccggt aaatactgct tagcttcttg ataagcttcc tgattcaata ctttatcttt
    54781 tgtcgccgtg atcgataaaa caggaacagc tgattctgtc aatgttcctt ttttgtcggg
    54841 ataacttgcc atgaagaata ccccttttaa atgtttgtct gaatgattct tattgacata
    54901 acgacttgcc attacgccac ctaatgaatg gccaccgatc acataatcgg aatttggaaa
    54961 atcttctttg accttatccg ctttgtttcc gcccatcact gctagatcaa gtggcatttt
    55021 gacaatagcg actgaaaagc cgttttttgc taaatcttgc gcccaaatac tataactttc
    55081 tggctctacg agagcaccag gataaaaaat aagtaatgga gactttccat gattcttttt
    55141 ctctccttca aaaaataagt aatcttcttt gttttttcct tcttttacca acacttgcgc
    55201 ttctgacgat ggttcgtacg tattttgctg tatatagtaa taaccggctc caccgagtaa
    55261 tcctaaaatg atgactaagc caattagtat tcgtctaaat attttcactt tctcccacct
    55321 tttctatctg agtgacccct ttttcttaat caagtatgat tataccttaa aaaaataaga
    55381 gagaaatgca aactttccag catcaaataa aaaaagacgg aatatccatt tgaatatccg
    55441 ccctttttgt atgtttattt ttatttagca cataaacgat acacagcttc tgcataaatt
    55501 tccattgctt tatacatact acttaattcc catcgttcat tcgcctggtg cataaagtca
    55561 ggagtatcag ggaacatcgc accgaatgcc acacactggt tcatcgtacg agcaaaagta
    55621 gcgccgcctg atacaaacgg ttcagtcatg tctccagtaa tatcgcgata tgtccccaat
    55681 agatttttca ctaactcact gtctagtggc acgtataatg aatcaaggaa gtcaaattct
    55741 tcataagtca acccatattt ttctgctgtt ttagttaatt tagctactaa atcatctttc
    55801 ttgaatgtaa cagggattct catatctaca ccgatttttg tttgttctgg tgtgatttcc
    55861 aaacttgcaa agttcatcgt tagctcgccg gattgttcat cttctgtttt gcccacgaca
    55921 gcttcaccag ttgcattttc ttgaactaat tttcctaaga aattgattgg gccaaaatca
    55981 aatacttctg aaagagcaat tgccagacga gaaatagcat tcactccttg tgctgcatct
    56041 ttcgcgtgga tacttttacc aagaacgacg atgccttcac cttgttcttc gaaatcgaat
    56101 tcgtgttttt tcaatgcttc ttttacttca gaaagctttt ctccagagta aggagctgca
    56161 tcaggaacaa cattcaacgc tcctccagct tttacagaaa actcgttcgt tcctggtcct
    56221 gtcaagtaag cttgcaataa gcctttttct gcataaatta aaggaaattc agcatctggc
    56281 gcaaatcctt gcgtaattcc ttcttctttt tcgttatatt tttctaaaca acgccataaa
    56341 ttttcttcat ctgtaccaaa gataaaacga atacgtgtct tgaattccac gccagcatca
    56401 atcaaagctt tgacggcata cattgccgca atagaaggac ctttgtcatc ttgggatccg
    56461 cgaccaacta accagccgtc ttttatagtt ggatcgaatg gttttgtttc ccaattattt
    56521 tcgtcccctg ctggaacaac gtccatatga cacaagatac cgaataattc atctccagag
    56581 ccaatctctg aataaccgta atagccttct ggatctttaa atgttctaaa tcctagcttt
    56641 tcactgattt ccaatacttt atccaaagct tcaatcactt ttttaccgaa gggatgtcct
    56701 tgtcctgaat ctgcttcatc tagtacggaa ggaattcgga tcaattcgct caatgattct
    56761 aatgcttgtt catgatgttg ttctgtcaca aattttttca tgatattatc ctcctaatat
    56821 gttaaaaagg gtcatgtcaa attcctccga cacaacctct tcttctcaaa taatgacgtt
    56881 ttaagcctgc tccatcagca agcagaatgt tcttaacaaa tgatgaaaga aaaaacactc
    56941 actgaatgga gctattgact tatccacgtg cttatcgata gccgtttatc ggtttcttca
    57001 ttcttatgat agaccttgta cctgtatttg tctaggttta gaacattgct gctacaccta
    57061 ggatcacaca gatggctaca aataatatcg caattaattt accggtaaat ttccaccaca
    57121 ctgaaacatc gaaacgagca attgctacag cacccattac gatagcagat gttggtgtaa
    57181 ttaagtttac taaaccagat gcagattgat aagcagtgat tactaaatcc ttaccgacgc
    57241 cggcaaattc acccataggt cccatgattc ccattgttgc agcagctaag ccggaagttg
    57301 aaggaatcaa gaatgacata gggatataga aaataaatgt aataatgatg aatacacttg
    57361 aagataatga acttaatcct tgttcgcccc aatgtaagat ggtgtctgtg attaatccat
    57421 tgttcataac cacttggata ccacgagcaa cagctactac gattgctaca ccgatcaaat
    57481 cagaagcacc agctaaaaat tcagagacaa attcagactc tttcatgcca taagtgattg
    57541 ctactacgat ggacattact aagaataaca tagtaatttc tgggaagtac cagtcaccta
    57601 atggaagcat gcttttacct agaaccgtac ctagtaccgg aaggtttgtt aaccagtttg
    57661 tcaatgattc aaaaatcgtg aaattcgcat tcaaggttgt ccaaggaatc aaactgatga
    57721 tcatgatacc aaaagtaata aagaacaata cattaacatg tttttgtttt ttcgtgatta
    57781 cttcttgacg accgattgct tcaatatcga aatgcttcat atcttcttta cgttggttgt
    57841 atactaatga ttttgttgga tctttttcga tctttgatgc ataacgatac acatatacaa
    57901 tagaaatagc taacaaaata acgaacatca agaatcgaag accaatacct tcacccatcg
    57961 aaatcccaac agcttgtgaa gctacgcctg ttgcaaaagg atttaccgtt gaagctagac
    58021 agcctacttg agaccctact aatacgattg ctacagctac tactgtatca aagcctacag
    58081 ccatcatgac tgggatcagt aaagcataga atggaatcgt ttcttctgcc attccgtaag
    58141 tagagccgcc taatgcaaat aacagcatca atactggaat aagcattttt tcttttcctt
    58201 tgaatttctt cacaactgaa gcaatcccgg catctagtgc ccctgttttg ttgataatac
    58261 ctaaaaatcc accaacaacc aaaatgaaga aagagattgg gattgcagca ggtgtttctt
    58321 tagttagctc ccccgctggt acacctagca tcccattgat tggcgccatg aaaatatccc
    58381 acagcccttg aggattttgt tgtactcgtt catatgatcc agcgacgatg ttgcctgcat
    58441 cgtctacact atagtgccca gctggtataa accaagtaag tacagcgatt actgcaataa
    58501 taataaataa gaccgtatac gctgaaggca tttgaaattt tttctttttt gtttgttcca
    58561 tcttcttctt cctttctttt ccgttagaga caacaatttt ggctctaatg ttattttatc
    58621 aaaaagagta tcagaacaaa aataataaca cgcattttgt aaaacttttg ttcaaaaagt
    58681 tcgtttttcc ctattccctc ctcttttttc aggtttttaa agctttcttc tttttcattg
    58741 tagcgtttcc ttttttttat aaacaaacat tttcgtcttt taaaaggaga agaatttcac
    58801 atttgcaaag aattgattga tttttatgca taaatcaaaa aaatactcaa aacaaacaaa
    58861 taaaacgttt acattattgc atgtcttgta tttttttcca aaaaaaaaga ccaagaaatt
    58921 tcttgatctt tttgatattt atttgactgc tgtatgacgt tgttcgaact gatgttgttt
    58981 tcgacttaac catggaagaa gttgcgcatg cagcactaaa aagacagcac tcacgatgaa
    59041 tcctttgatc aagttgaaag gaacgatccc aatcagtaca tagtttgcta aagacatgcc
    59101 cagcatctgt gttgcgttca gccctaaaaa cattaagtaa agaggcgtaa taacgaaata
    59161 atttgcgata ctcataaaaa tagttagagc gatggttcct gtaatgacac ctaaaaattt
    59221 gtttcttcct ttatgctgtt tctttacact aaagaaataa taaatcggga atgtaaagat
    59281 cgttgttgat aagaaactag cagtgtctcc taccaaatta tccggagaaa aacctgtagt
    59341 cagcagatgt aatactgaac gcaagaacgc tgttgcaact ccggccgctg gaccgaataa
    59401 gaacatgctg atcaataccg agatatcact aaaatcgatc ttcaaaaaac taaaagccgg
    59461 catgatcgga aaagcaaaat actgtaaaac taatgcgatc gcagcaaaca tcgctactgc
    59521 aaccattttc tgtacacggg tgttcttcat ttgaaatcct cctgttagga ctcctcttca
    59581 gcgaactttt tgacgtttct ctccaaatga aaaaactcta ttttccaggg aaaatagagt
    59641 tagagttatt tgatcaagcg tcgtcaaata agctctatct tctttatcca gactatactg
    59701 tcggtatcgg aatttcaccg attcagctat ttttttgcaa aataggtcgt ggactataac
    59761 caccggtcgg gaatttcacc ctgcccctga agacgaacct tatataattt ttgtttacat
    59821 attcattata catatctatt caaaaaacgc aacatctaac acttataaaa agtaagtgtt
    59881 cattttgagt ggttcagcaa actgctgact tcttttttgt tcagttcacg gtaatcccca
    59941 ggacgtaggc cttgtaaagt cagatctccg tatttttcac gttttagttt ttgcacagga
    60001 agaccaactg cttgaagcat atttttcact tgatgattac gtccttcgtg gatcgtcaat
    60061 tccacgatac tgtggtttgt cttaggatcc actgataaaa tttggaattt agctggagat
    60121 gtttttcgtc cttcgatctt tattcctttt gtcaaaggtg caagcatcga ttttgtagcg
    60181 atccctttta cctttgcaac gtaaacttta tccacttcat gttttggatg tgtcaggcgc
    60241 tgagcaaaat ctccatcatt tgtcagtagc aagatccccg aagtatcgta atccagtcga
    60301 cctacaggat agatacgttc ttttaccatc ggcaaaagat ccgtaacaac ttttcttcct
    60361 ttgtcatctg caacagcaga aataactcct ttaggtttgt acaataaata gtaaccgtat
    60421 tcttcttgat aaattgggac ttcatccact tccacagtgt catgtttccc aacttttatc
    60481 cctaattccc ttacaacttg tccgtttact tttacacgtc ctgcaaggat gaattcttct
    60541 gcttttcgac gagaagtgat gccagcgtgg gcaattactt tctgcaatct ctccattaca
    60601 attattctcc tttattcatt ccatcaaaga atagatctgg tgacacgtct tcttcaagtg
    60661 aaatttccat ttcttgtgta tcaggcagtt cttctaatga tttcaaacca aaataatcta
    60721 agaagtagcc agttgttcca tataatatcg gccgacctgg tccttctact ctaccttttt
    60781 cttcaatcag tttatgggca gctagacgct gtaccgctcc tgaaacctga actcctcgaa
    60841 tctgctcgat ttcagctctt gtgattggct gtttataagc gatgattgct aaggtttcga
    60901 cggcggcttg agataatgtg tttgatgtcc cttgcgcata tcgcttaagt aagggagcca
    60961 gctctttttt agtcgttaat acataatggc tttccgtttc aaaaatatgc aaagctgagt
    61021 gcgagttttg agtgtaagat tcttttaatt ctttcactaa acttgtgact tctgcttcgc
    61081 tgagatttaa cagtccgctt aattcttcat tactgatccc ttcctcgcca acaataaaaa
    61141 gaagggcttc aagttcactt aatttcgtca tgttcggtat ctcctactgc tggataaagc
    61201 ataattgatt catagttttc tttttgttgc gcaatgatct gccctttttt catcaattct
    61261 agcaaagcca taaaagtagt gacaacttca cttttagaag gtgactcaaa aaaagaatcg
    61321 aaagtacagc catgcgcatt tctttttata cgctcttcga taaataccat tcgttcttcg
    61381 atcgttgtgt catcgggcgt gatcgttttt tccacttttt gagaaaattt cttacgttct
    61441 aagattttct gcatggcacg gatcaaatcg atttttttga cttgtcctcg cttcaacggc
    61501 ttttcagcat ccgctaaccc atcgatgttc ataggttctt ttgtgtaata aagacttcgt
    61561 tcctctgctt tttctgtcag tctttcagct gcatatttat atttacggta ttctaaaagc
    61621 tgagtgacca attcttctcg aggatcttct tcccataatt cttcatcgtc tgtgacgaat
    61681 tcttggacag gaagcaatgt cttgcttttg attgccatca atgtagcagc catcactaag
    61741 tattctcctg caacagctag ctcgagtgtt ttcattgtat ggatataatt catatattgc
    61801 tccgtgatcg tagcgatcgg tatatcatat atatcgattt ccatttgctg aatcagatga
    61861 agcagcagat cgagaggacc ctcgaataca tctaatttaa tattgatctc cgtcaactca
    61921 ttcactcttt cttctttttc tttgctagcc attttccaat gtaaggctct gtgatttcag
    61981 ttgcacggat ggagacatcc gggtactttt cctgtaattc atctaacatt tgaaagccca
    62041 tattctcacc gcgataagac ggattcaaag aaatgtcatg gatgatcagc tgatcgttcg
    62101 ttgcccagta aataccaata atcccttgaa tgttggttga accttctggc gtaaagaaaa
    62161 aaagttcata atcgtcttca gattcgtacg tatcaatctc cttcaacaaa gaagttttac
    62221 ctgtcagttt cttatggaaa ctcaatagtc ccatagcaat tttacggttt tctttccggt
    62281 aatgtgttaa catcttctca ccttcctatg actaagccct tggaaaatgc tgcttataaa
    62341 catccgtcat tcttttcttc gtgatatgtg tataaatctg agtcgtagag atatccgcgt
    62401 gacctaacaa ttcctgtact gtccgcaaat cagctccatt ttctagcaga tgtgtggcaa
    62461 agctatgccg cagcgtatgt ggtgttactt ctttgtaaat cccagcctct cgtactaact
    62521 gcttcagatt tttccagatt ccttgccgag aaagaccttt cccatgatta ttgacaaata
    62581 catgcatttc agatgcgtcc tttacaagta atggacgtgc ttcgtctaag tagcgttcca
    62641 gccattggat cgcataatca cctaaaggaa tgatccgctc tttatctcct tttccaactg
    62701 tctgtaccag tccaagagaa agatgaagat ctcccaattt caatccaatc aattcactga
    62761 cgcgcatccc agtagcatac atgacttcca agattgcacg atctcttatc cctaacgttt
    62821 ttgtcgtatc aggtgcttca atcagctttt ctacttctgt cagagtcaat gtacttggta
    62881 atttctgtgc tttcttcggc gtatcgatat gttgcatcgg atcatgatca gtgatacgct
    62941 cttgccgtaa aaactgatgg aatcttctga gacttgagat catccgagta acagttgctg
    63001 tcgctttttt ttcttcatgc aacttctcca gaaaacggat gactaaaaag cgatcgacat
    63061 cctgccatga agcaattttc tgctcctgta gaaaatgcaa gtactgttcc aaatcacgtt
    63121 catagctttg tcgtgtattg gcggacaatc cccgttcaat attcaagtag tggagataat
    63181 cgttgatttg ctctttcata ataatccccc tcatgcctct ctatcatatc agataccgct
    63241 tcattctgat agtctttttc cataatctga gcaaagaaaa agccgtctag acactcagac
    63301 ggactggttt cttttttctt tttcatagca ttcctgacag attccatgga acgttagccg
    63361 atgatctttt actaaaaaat gataacgttc ttctactact tgctccactt caagtaaaag
    63421 atcctcttct acttcctcga tcgtgccgca gttcaagcat agtaaatgat gatggaaatg
    63481 tttggcgcct tcttttctca aatcataacg ggctaatcca tcattaaaac ttactttatc
    63541 gacaattttc aattctgtca agatttcaag ggttcgataa acagtagcaa gtccaatttc
    63601 cggactcttt tttttcacta aaaagaagat ttcttctgca gataaatgct ctttctcatt
    63661 ttccaaaagc acaagcagag tagcttctct ttgcggtgtc agcttaaacc ccgcttcatg
    63721 tagctgctgt tttgtttttt tcatcgccga aatagcattc atgaccattt actcaacccc
    63781 aacaatttat aataattaca aataaaaaaa gatataacac tatgttaatt aaaattatta
    63841 taagctagtt aagaaaaaca tgcaagggat tctcaattag attttttgac tagttttgtc
    63901 acaccgtttt cttgtgtaat caatccttgt ttcaaaagat tacctaatgc gcgcttaaat
    63961 gctcctttgc tgataccaaa agctttcatg atttcttctg gatccgattt atctgtaaag
    64021 ttgatttgct gatctgcaga acgttctaaa atggttaaaa tcatttgtgc atcatctgat
    64081 atagcttcat atgctcttgg cttcaatgaa agattcagta caccgtctgg tcggacacca
    64141 atcactcgac cttttatctg ctcgcctaga cgaggttcat tatatcgttc agaaggatgg
    64201 ataaacccaa gatagaaatc ttccgttaaa acgtacgtac ctgttaattt caagcggtat
    64261 gctgttccta tcacatcttt gtttttcatt tcttctgttc catatttgct taaagatttg
    64321 aatatttttt catctgctaa actgccccaa atacggtctt ttgcatcaac tctaagggaa
    64381 atcatcaagc gatccccttt tttaggccat agctctgtca ttgtcggcaa ttcatcaaga
    64441 gatacgacaa agtctttatc tggaagaccg atatcgacaa acgcacctaa atcttttcgt
    64501 gtagcagtaa cgattccaaa agcgtaatga ccgatacggc ttttaggaat ttgtgtagtg
    64561 atccgatttt catgtttttg attttggtaa ccgaatcctt caactgcttc accgattttg
    64621 tgttcacctt ctgatttgct taagccaaag gtttgtccgt ttttttggac aaagtagttt
    64681 ttttcatttt catcaataat aatacctgta aatatagttg ctaataaatc gttcattttt
    64741 ttctccctct atagtgaaag gttttcttaa tacatttctt tgctatcata acataatgtt
    64801 atctacttga atagctgagc cttggtttgg aaaggtgaaa aaaggagtat gacaacagtt
    64861 gtgtcatact cccctttttc gaataaacgg tgttaaacgg caggctcaca gcctctttca
    64921 tttgcctaaa attaattgct cccatttcct ccgaaccatc cagttttaca gttgatggtt
    64981 acgatgtaaa atggcaaagc actttctcca atgcctttca tcaatgcaga ttttgttgaa
    65041 gtggcatata gattataata gccttcccca ttttcgattc tggctttttc taatctgtaa
    65101 cctccttcaa cgatatatcc acgttggata catgtagcaa tcactttgct ttggacacct
    65161 ggtgcccacg tccatgctgg attagatgca tcggcaatat cacttgctct ggcagatttg
    65221 attggctgat tcgctgagtt tgaagaggaa ggggtcgagg atgccgcttc ttgctgtgct
    65281 gcttgtgcga ccgcagcttg ttgagcggct tgagctgcag ctgctgcttg agcggcttgt
    65341 tttgcttgtt cttcagctgc ttttttcgct tcttctgctt ttttcttttc ctcttcttct
    65401 tttttctctt tatcagtgag catcttatct acttgtttca attgttcatt caactgagca
    65461 gatagatctg tatttttcac tttttctact gcttcttttg ccgtcttgta ttggtcgcgt
    65521 gttgctgaat ccactacttt tccgtcttta aagactatag ctgttttttc tttagctgtt
    65581 tgcaattcag catattgatt tttagcttct gtttgtgctt gttgaatcaa ttttccaaaa
    65641 tctgtgttat ccgtttcgat tgcttggatc tctttatctg ctttcaactt gatgtcatct
    65701 gctagatgat catcgacgat ggcaggtgct atgaaccact cattcacttt ttggatatct
    65761 cggatcttag attggatatc ttggtaagtt gtttctaact ctgaatatcc tttttcattc
    65821 ttaagactgg ataaatcatt ttttagtttt gataaatctt gatgaatcat atctgcacga
    65881 ataaattgat ggtgatcatc tgtataaaag gcagcaagtt tctcatgaag ttcttccatt
    65941 tgttgctgtc tttttgcttc tgctgctact tcggcttcta ctttttgatg atggtcataa
    66001 taagcccagc ttcctccacc gagtagaagt actgctgcta aaacgagata aggtactttt
    66061 tttgattttt tcttttgcgc tttatctgga tctgtttttt ctaagtttga ttcttgatgt
    66121 gttttttcag tatctggcac gattgttatt gatttcgctt ctgcttcaaa cagcttaggc
    66181 tggttctctt ctttttctat ttttgcttca agatcagtac cctctttgct tacagattga
    66241 ttttcagcat cggattcact atttatttca tcgggctctg ttgacttttt gtctgtgttt
    66301 tcgagtattt cttttttctc tgcttccggc agtttattcg ttttttcctt ttctaattgt
    66361 ttttcagtaa atacttcagt tttttctgtg atatccgttt ttacgtcttt tatttttact
    66421 gtttctttac ctgtggcgtt ttctctatca gagtcttttt cagtttcttg ttccttttct
    66481 ggctctactt tgttttcctg tgcaattttt tcactgatca ttttgagcag ctctttcgcg
    66541 tgctcttctt ttgtatcttc acgatgtgct ttgatataag cggatagtat cgaattttct
    66601 tcctcattat cgacgatttc tttcagttca gctactcttc ttttttgttt tgattcaagc
    66661 gtttcttctt gattctttcc tgattcttcc gaagtctcat gaacagttgc tttcttctgt
    66721 tcatttttct ctatattagt tacttgatcg tgagcaggtg gttcttcgtc ttctggttct
    66781 gctttttcga ataattccat tacagattct agaggtaaat ctttcaattc cgaccattcg
    66841 attggatcgt ttaattctgt atcaggaaag actgcatctt cagttgattt atcctgcata
    66901 gctgcatctg tatttgtttc ttcaattgat tcttttattt gctgatcttc tgcagttatt
    66961 tgatgaccgc agtctggaca gatagtattc tgctccattt ttttcgatcc gcaatttgga
    67021 cattttttca tcacttagcg atcggctcct ttactaggtt tacgctacca tttaatctat
    67081 catattctat acgtcacgcc aatagcttat ttttaggatt tacttaaaaa taatgaatga
    67141 atttccttcc tatagaaaaa aaagcttgag actgcgtagt ctcaagcttt ttttctttta
    67201 aaataaacca aacagtttta ctgatttctc ttctggtcaa tagtccacgc ttattctaag
    67261 aaatctttta attgttttga acgagaagga tggcgcaatt ttcttaatgc tttagcctcg
    67321 atctgacgaa tacgttcccg agtaacacca aatactttcc ctacttcttc caatgttctc
    67381 gtccggccat catctaaacc aaaacgtaag cgaaggacat tctcttcccg atcagtcaat
    67441 gtatctagta catcttccaa ttgttctttt agtaactcat aagctgcgtg ttctgctgga
    67501 cttgttgctt cctggtcttc tatgaaatca cctaagtgag agtcatcttc ttcaccgatt
    67561 ggcgtttcaa gggaaacagg ttcttgcgcg attttcaaga tttctcggac tttttctgtt
    67621 ggaagatcca tttccgcacc gatttcttct ggcgtaggtt ctcttccaag gtcttgcagc
    67681 aattgacgtt ggatacgtat caatttatta attgtttcaa ccatatgaac tggaatacgg
    67741 atcgtacgtg cttggtcagc gattgctcga gtgatggctt gacgaatcca ccatgtagca
    67801 taggttgaaa acttaaatcc tttgcggtag tcaaattttt caactgcctt catcagtccc
    67861 atgtttcctt cttggatcaa gtcaaggaac tgcatgcctc gtcctacata acgtttagcg
    67921 atacttacta ctaaacgaag gtttgcttct gccagacgct gtttcgcttc ttggtcgcct
    67981 tcttcgattt tcaatgctaa cgctacttct tcttccgcag ttaaaaggga gacacggcca
    68041 atttctttca gatacatacg aaccgggtca ttgattttta caccggttgg cgcagaaaga
    68101 tcttctgttt ttgcttgttc agcttttttc tcagcactct tcaagctgtg aattgatgga
    68161 tcaccatttt catccaccac actgatacct gcgtcttcaa tcttttggat caatttgtcc
    68221 atttcatctg cattcaaagt gaatggtgta gcaagctgat tggataaatc atcatataca
    68281 acttgtcgtt tgggtttgtt ttctttgatg aaagctgcta ctgctgcttc atacgttttt
    68341 ttatctgttc catttgccat aaaagaaggc cccccttgag tagctatttg gcttgtttta
    68401 actgtttcgt taaattgatg atttcaatcg tcaattcaag ctcaagctgt ttgtttccag
    68461 ttcgtctggc ttcttgctgc atttgttttt ttaatgttat ttcatcagct aagccagatt
    68521 tgctgatcac atctagcaag tcttggattt ctcgtggcga actttcttct gccaccggta
    68581 aatattcgat ttccaccacc aaccgcctta aattttcatc ttgcaaaaag tctaaaaact
    68641 ctgcaaggtt gaattcataa tgttgtgaga catatgcatc gaataaaaaa taaacttctg
    68701 catatgcatc atgaataaac tgaaattctc gttcttttaa aatattacgg acagaaactt
    68761 ctttaaatgc acgatataat agaatctgct ctgccttttc tacttgcgtc aaaggtctct
    68821 ttttccgtgc agtttcttgt ctcgtaacct gagtgtgttg actttcctga ggttcttgac
    68881 gattttgctg atttgtcctt cgaagatcgc gcagttgttt ttgtatcgtc tctctgccga
    68941 tctgaaactc tgttgacagt tgagatagat acatatcttg ttcgattggt gaaacaactc
    69001 ggctaagttc aactagtaat tcttcgaggt attcgatctt gtctttttca ttatctaaat
    69061 ttttcccttg ttttaaataa cgtgatttaa aagtaaagac tgtttcgcgc ccatgagcca
    69121 ctaattcttg gaaagatgct tctccatact tacggagata ttcatcagga tcaagctttt
    69181 ctggaacgac tacgacagaa agtgctaatc gactgttttg ccgaagcaat tcaatccctc
    69241 gattggttgc ttcaaaacct gcgttgtctc cgtcatagca aaagaccaat tctttcgtca
    69301 gcttttccat ttgttggatc tgttgagctg ttagacttgt ccccatagaa gctaatccag
    69361 ttttgatacc agcctgccat gcagcaatca catccataaa cccttcgaac aacaaaattt
    69421 ctccgttttt ccggatatcg cttcttgctt tatcaagatt aaataaaact tgtcttttat
    69481 tgaacagttc tgtttctgga ctattcaagt atttgggctg atctttttcc tgcccttttt
    69541 caggtgcaag ccagcgtcct gaaaaaccga tcgtctggcc ttgagaatta cgaagtggaa
    69601 acatcactct ttgataaaaa cgatcagaca tacggccatc atcatgcgtg acaaacaatc
    69661 cagagcgttc taacaattca tttgaaattg attcattctt gaatacttgc tgaagaaaag
    69721 aacgctcatt aggtgcaaaa cctatgttga attcttcaat taattctaaa gacaacccac
    69781 gactttgcaa atattctaaa gctggctgtc cagcttttgt atgcaatagc atgtgatgat
    69841 agatttccgc tgctttttca tgagcagcaa tcagtttccc cgtagcagat tcaggatttc
    69901 ggacagctat agtacgctga cgccattgat cttctaacgg tatctgttcg aagtctgcca
    69961 cttttaccac tgcttctgga aaacttagac cttctagttc ttgaagaaaa gtaaacacgt
    70021 ttccgccttt accacaacca aagcaatgaa aaatctgctt gtcttctgca acagaaaaag
    70081 acggtgtacg ttcttcatga aaaggacaca gccccaagta atttttacca gactttttca
    70141 actggacata ttgtccaatc acctcaacga tattcgtttg actgcgtact gtttcgataa
    70201 cctcttgagg aatccgttga gccatttttt caccccctgc tctattgata tcttttgggt
    70261 ttaacagaag atatttcagg agaataaccg gtaaaaaatc gcactaactg aaatcagtgc
    70321 gattttaaag gacacaatta tacatgtttg attgtatcat atttcattgc tttttcaagt
    70381 ataacacatt tctatctcat taagcatcaa tttgctactc ttttcagtaa ctgattttga
    70441 atatcagcct tccagtacaa tactcgaaga acaatattta cgagcatgaa tacaaagaag
    70501 tatcctacgc tctctcccaa ccctaagttt acttccaaaa ttccatggaa cagcattgca
    70561 gctacatata tccctacgat cgtcgttact gctaggaaga tgcgcaatgg gttgaaggga
    70621 taacaagctt ttacaactgc catgcaactg atcccaatca gcaagtaata catcaaagta
    70681 gtagtttcag catttcccca tgcgaatgtt tttccaagta gatacaccgc aatgatattc
    70741 actactacaa gcaaggcatt tggtaaagca ttaataagtg ctgtaggcaa ataacggtaa
    70801 gtgatttttc ttttatcttg ttcaaaagat aaaaagaagg aaggataccc ttcaatcgct
    70861 aaatcaatca gcgtgatttg gatagggata aacggaaatc caattgctgt aacggcacat
    70921 ataatcgata aaataaatga ataaatcgtt ttgataaaaa agatgcctga gactttcgtc
    70981 acattgttga ccactcggcg tccttcaaac aggacttctg gcaatgtagt aaaatcagag
    71041 tccaacaata ccagattcgc aatctgacgt gttgctccat caccttctgc catagcaatg
    71101 ctgcaatctg cttctcttaa cgccaaaaca tcattcacac cgtcgcctgt cattgcaacc
    71161 gttctgccgc tttctttcaa ttcatttacc agcaatttct tttgctgcgg actcactcgt
    71221 ccaaaaaccg tatagcgatg agcagcttct cgcacttcca tttcttcagt aatttgagaa
    71281 agatcgacat acgcatcata attcggtaat cctgcacgtc tagcgatatt ggagacagta
    71341 aaaggattgt ctccagaaat cactttcaga tccacacctt cctcatgaag ataagctagt
    71401 gtttcttgag cgttttttcg gattggatca tcgatttcaa acagagcaac cggctcaaca
    71461 aatgctggtt tttcttcgtt caattgctga tttggagcga tccccaacat aagtacgcga
    71521 tagccattcg cttgggctgt ttttagactg tccggaagcc gatcttcttc caccaaacgt
    71581 tcaggcgctc ctacgtacac gactcccagt tctggaaatt ccatcgcgcc ccatttgcga
    71641 tcagaagaaa atgcgacttt gtttgtcaca tcataccgat tagaaagctc aaaataatct
    71701 ctcatagccc gcatagtgat gttgttatca ctgctttctg ccagatacgt ccccataatt
    71761 tctgggatgg ctttctcgta cagcggatgt agtgcttcta cccgctggat actcattttc
    71821 ccttcagtaa tggtccctgt tttatccaag cataatgtat cgacatgggc cagcgtttca
    71881 attgaataca tgtcttgaac aaggattcgt ttttttgcca gtttggttac ccctgtcgtt
    71941 aatgcaatac ttattagcaa taccaaaccc tttggaagca tgcctaacaa agctgctgca
    72001 gatgcaataa cagaaatttt gatagaagca tcgcggatga acagtgcttc caaaaatagt
    72061 atgatcccca aaggaataat cacgaaacta gtgaatttgg atactttgcg aatcgaatct
    72121 acaagttcag aacgaatagc tttgtgagtc tttgcctcgc tagtcaagcg gacagcataa
    72181 ttatctgcac ctactcggat aacttcagcc atgacagaac cgcttgtcaa aaagcttcca
    72241 gaaagcaatt cagctccagt ttctttgaca atcaaatcag attcgcctgt caaaagagct
    72301 tcatttgctt ctgcccgtcc agatataacc tgtaaatcgg ctggtatctg ttctcctgct
    72361 ccgattttta ccaaatctcc taataccagc tctttagtag aaatcgattg ttctttaccg
    72421 tcccggatca ctagtacttc tgattgggaa acaatcgata atttccgtac aagatttctt
    72481 gcatgtattt cttgataaat tccaataacg atattgacga caataattgc taaatacgcc
    72541 atgttggaat acgcacctac aaataacaga caaatcccaa taccaaagtt cagaaaattg
    72601 aataacgtca atatattatc gctgaatatt tgttttgtac tttttgatgc atcttcctgg
    72661 tagtcatttt gctggccaga agccattttc tgaactacct cttgctgtgt aagtccattc
    72721 attttctttt tctccatttt ccgccaactt tcaaaaataa tcacgtgttt aagtctagcg
    72781 tgttccaaga ttaaaaacaa cttgttttta taaaatttat agaaaaacac acgaatgatt
    72841 ttacaaaaaa gatgccaacc tttttgtttg aatcacccgt gtgctgtttt tattatcaat
    72901 ctatctttac ttatattgtt cctccaaacg gctcatccac caacctagtg ctgtaccggc
    72961 tataaaaaga acaggacaag ctagtacccc agcaactccc aatcccgcgt aatcggtagg
    73021 aatgatcata atcgttgaag caaaaactac acctaaaatg aaatggaata gcttgctata
    73081 tgcctttgag aaaatgtaat ccatgatttt tgacaatcca agaacacaaa gaatcccacc
    73141 aattccgatc ggcacaatca cttcaagtcg tacttcttta aatccgtcag ccatcgcttt
    73201 atacaatccc atatacacca aaaaattaga agggctcaat cctgggacga tcatacccaa
    73261 accaatcaat ccgccggcaa tcagccatgt tccaaaattc tgatcgactt gcccgtcaaa
    73321 taattgagcg ccgtataata aaaacaaata agccagaaca aaagtaacaa ccatgatgat
    73381 cacatcagaa gtatctcttc cttttttccc tgcttctttc cataacgcag gaacagttcc
    73441 agcgatacat ccgacaaaaa accataatat cgttgtttca tacgcaccta ataaaaaact
    73501 gactaaaaaa gaaagtagaa agatgcctgt cactccgcct agaccaacag gcagaaaaaa
    73561 caaaacattt tctttgaaat tttttgtaag gtgggctaaa aaagaaatca gccgctcata
    73621 catgccaaag acagctgcta atgcaccacc gctgactcct ggcaagataa atcctgaacc
    73681 gataaacatt cccttcacaa accgtaacat ccagtctttg gttgtgtacc ccacttcttg
    73741 attttccatt ttttgccttt tttccactat ttgcgtactc cttctttcat ttaattttat
    73801 tcatgattga acatttcctg ctattttact taaagacttt ttcataggtc tctattattt
    73861 tttcattcat tttgacaata tcaggataaa acatgttacc tccattatga tagagatagc
    73921 cgccattgta aagcaaggac tggatccgcc aatatcggta ttgtttccct tcctcatttc
    73981 ctaaaagtgg gctcagcaca tctttagaat acgcttctgc taattctact gtgttttctc
    74041 cgccatgatt ttttacatag gcaatataat ctttcccaaa attatatgct tggacagctg
    74101 tccataaatc gcatccttgt ttctttgctt ctactatcat ttccgccaaa tatttgacac
    74161 cttgatcaat actgtcagct ggattatcaa tgatctcagc ttctccatgc agactttccg
    74221 agctctgcat gagatctgtc ccttttcctt ttgattcggt caatattatc gccttgatca
    74281 aattctcgta gttttccata tgataatttt ttgcagctgt tgttatttct atttgatagc
    74341 tttccactcg ttttaccgaa cgataagttc ttcctcataa aaacaacacc gcaccaataa
    74401 ccgtcagaat gatcatgtaa aaaagaatac ggataataga taatcgtttt cgcttcattt
    74461 catcacctag ttattttgac atcttttttt atcttactat ttctttatct tcttggctat
    74521 ttcttccttg atttctgtgt acgccttaag aaaaaatgaa ttttcctgta ttttttgaca
    74581 tcttacgaaa atgatcgttg tttttcagta aaaacaattg cccaatgact gatataatcg
    74641 ttatacttta cacagtaggt gattatgtga aaaaagaaaa gaaatatgca aaaatgccag
    74701 atgggagcga aatttactat gaaaagagcg gtcaaggctt ccctctcttt ttactgcatg
    74761 gcaatgacgg cagcggccgc tttttttcag aacaggtccc tgtactcgaa cgctactata
    74821 ccgtgtatct agtagatagc cgaggacatg gtcgttcgac aaacgaagca tctatgttga
    74881 attttcagtt aatggccgag gatctgaata cgatcatgtt gctggaaaaa atcgatcagg
    74941 cagattttct tggatttagt gatggagcaa atctagcact ggtatttgcc agcagcttcc
    75001 ctaaaaaagt tcatcgattg attttaaatt ctggaaacac gcttgttaaa ggcgttcgtt
    75061 tttctgccag agtcatcagt aatattcatt atgcatgggt atggttactc tctttatttc
    75121 gcccaagtct tcgcaaaaat cttttagtta tcaaactttt gctgcatgac atcgggctta
    75181 cagaaaatga tttaaaaaaa atcaactccc ccactttgat catcgtggga aaaaaagatg
    75241 taatcaagct aaaacattct ttgtatatag ctaaaactat accaaaagct tcctttgtgc
    75301 ttgtgaaaga acaaggacat gaattagcta gaaaagatcc tgaacgcttc aatcgagaag
    75361 ttcttcaatt tctttctgaa acataactat taggaataga aggtgattta tttgttaaaa
    75421 aataccatac aatggctgaa aaaccaccta ggactgttca aaacaatctt tttgatttct
    75481 gtcattgtca ttattgtcgg tgaattgatg tccatcggta aaactctatc tatccagcaa
    75541 ttaggagaaa cgtttgccac tatacctgta tggaaaagcg gactaatgct attgattggt
    75601 cttatctctg tgttacctat ggttggttat gatattattt tgaatcggat gcttgaacaa
    75661 aagcagaatc ctcgttacct gtttgagaca agctggctga tcaatacgat caacaatatt
    75721 gccggtttcg gcgggtttgt tagtgtgggg cttcgctctg aactatatgg acaaaagaaa
    75781 gagagcagaa acgtgatcca agcattatcg aaagttttct tgtttttgat ggctggactt
    75841 tctatttaca gtctgctttc ttttttactt gtagtcttca cgccagttgc tccttttttg
    75901 aagcaatatt ggatatggtt gatcggcggc ggtctatatt ttcctgtcgt ctttttattt
    75961 actactttca aaaagaaagg attccttggt ggtacctcac ttaaaactca aggacagcta
    76021 ttgctagttt cattgttgga atggaccggt gtcctgttta gtttcctttc tgttggttat
    76081 ttaatggaaa tccggattga tctgtggcaa acaattccat tattcattgc tgcttcagtg
    76141 ataggaatcg tgtctatgat tccaggagaa attgggagtt tcgatgtaat gatgattatc
    76201 gggttgtccg ctattggtgt gccaagagaa atagtcgttg tgtggatctt gctctatcgc
    76261 ctgttctact acatcattcc gtttttgatt ggaatcgtct ttttcttcaa aaatatcggt
    76321 tccacttttg atcagcgtta ttctggtatc cctaaacaat tagcaacaga aattgcgcat
    76381 aaaatcgtgg ttgtcttatt atacttttct ggaatcatgc tagtactttc tgccactatc
    76441 ccgcaagctt ttacagagtt tcgctggctt catagtttga acccattgaa atttcatttt
    76501 attatccaat ttcctagtat actattggga tttcttttaa tcattatggg cagagggatc
    76561 gcagcacgtg tgaaacgagc atatttgcct acaatcttct tgattgttct agctttactt
    76621 tatgttttat taagtgattt tagtttcaca ccggtggttt tcttgtctat tctgcttctg
    76681 atcattcttg cttctaaaaa cgaattattt cgggaacaat tgatctattc atgggagtgg
    76741 cgtacgatcg atggaatcat tattggtgca ctgtccttgc tttacatcgt tattggggta
    76801 tacaatctgc cggatttccc tcatcggcgt caccatttta tttccttttt cttatttcct
    76861 tctgaaaaga tttggttttc gggattgttg gccatcatcg ctgttagttt catgatcgtt
    76921 ctatttgttc atttccttca aggagaaaag aaacagattg gcgaagcctt taatgaagaa
    76981 aaggccctga agatccttac aacttatgga ggaaactccg atagtcaatt gatcttctta
    77041 aaagataagc ggatgtttgc ctatgaaaaa gacggtgaac caactgttct tctccaattc
    77101 gcttgcttca ataataaatg tattgtaatg ggtgatcctt ctggtaagaa agaagatttt
    77161 ccagaagcaa tcgaagcttt tatcgaagaa acagatcgac tatgctattt accagttttc
    77221 tacgaaacaa gcgaagagat tgttatgatt ttgcatgaat tcggctacga tttcattaag
    77281 atgggggaag aagcttatgt agacctgaat agttttacaa cttcagggaa aaaaatgaag
    77341 ggcactcgtg ctgtcttgaa tcggatcgaa cgagaaggat ttacatttga tgtcttacaa
    77401 ccaccatttt ctactgagca aatgagtact ttcaaaaata tctctgataa ttggttgggt
    77461 tcacgaaagg aaaaagggtt ttctttaggc tttttctctg aagattatct acaaagagcg
    77521 cctattgcag ttgtcaaaaa tacccaagaa gaaattgtcg cttttgcaac gatcatgcct
    77581 acttacacga acaataaagt aggaacgatt gatctgatgc gatatgattc taaaaaagca
    77641 ccttctggca gtatggattt cttgttcttg catttgtttg cctatatgaa agaagaacat
    77701 atccaatggt tcaatttagg gatggcccct ctttcaaatg tcggaacttc cagaaagagt
    77761 tttttacagg aaaggattgc atacttggtt tacgagtttg gttctcattt ttattctttc
    77821 catggattaa gagaatataa aagcaagtac gctacaaact gggtctcacg ttatactcta
    77881 tattctagag atagttggat tgcatatgtt atgattgctt tgctgattat tgataatgcg
    77941 ccagttgagc agacacaagg tagaataagt ggtttgaaaa aatggatacg aagaaagtat
    78001 taaaaactgc ataccgatag atgaacactc tcatgatgaa taaaagagac tgaagtaaaa
    78061 cgaaagttca tgcttctaca atctcttctt atacaattga agaacaaaga gcggtccaaa
    78121 cagaaatcct gtttggaccg ctcttttatt ttaaacattt ttcattacca aaatattcga
    78181 gtcgcgtttc ttatgcttcg atctctgtaa cgatacctga acctactgtc cgtccgcctt
    78241 cacgaattga gaatgtcgtt ccgttttcaa cagcgattgg atggatcaag tcaacatcaa
    78301 tcgtcacgtt gtcaccaggc atgaccattt ctgtatcttc tggcaatgtg attgttcctg
    78361 taacatcagt tgtgcggaag tagaactgtg gacgatagtt gttgaagaat ggagtatgac
    78421 gtccaccttc ttcttttgtc aacacgtaca cttctgcttt gaattttgta tgtggagtaa
    78481 tggaacctgg tttagcaagt acttgtccac gttcgatatc gtcacgttgg atcccccgta
    78541 acaacacgcc tacgttatcc ccagcttccc cgtaatctaa cgttttacgg aacatttcta
    78601 cacctgttac aactgctttt tgtgtttcag gtttgatccc tacgatctct acctcatcac
    78661 cgacacgaac agcaccacga tcaatacgac ctgaggcaac agttcctcga cctgtaattg
    78721 agaagacgtc ttccactggc aatagtaatg gtttatctgt atcacgttct ggtgttggga
    78781 tatattcatc tactgtatcc atcaattcca taatagcagc ttcagcatct ggatcgcctt
    78841 gcaatgcttt taatgcggaa cctttgatca caggagtgtc atcgcctggg aaaccatatt
    78901 cgctcaataa ctcgcgaact tccatttcta ccaaatcgat caattcttca tcatcgacta
    78961 aatcaacttt gttcaagaaa acaatcaggt attttacacc aacttggcgt gacaataaaa
    79021 tgtgttcacg tgtttgaggc atcggaccgt cagttgcaga aacaactaag attgcaccat
    79081 ccatttgtgc tgcccctgta atcatgtttt tcacatagtc cgcgtgtcct ggtgcatcaa
    79141 tatgcgcgta gtggcgtttt tctgtttcat attctacgtg tgcggtattg atcgtaatcc
    79201 cacgttcacg ttcttctgga gctgcatcaa tactagcata gtcttgagga tttgctaggc
    79261 cttttttgcc taatactgta gtgatcgcag cagttaaagt agttttccca tggtcaacgt
    79321 gtccaatcgt accaatgtta acgtgtggtt tacttctgtc ataatgttct tttgccataa
    79381 tttacaaacc tcctaaataa tatagatcac tgaaaaattt cagctctcac ctttttatta
    79441 tagtcttttt ttgactaaat caaaaagaat acgtccgact tactttttgt aagattcgaa
    79501 ctaagcttat tatacgtcaa tattggtcaa agtcaactaa gagcactcgt ctgtcttata
    79561 cgcgaaaaaa gtacctttta taaataaaaa aatgtgtttt ttgagaaaaa cttcaagata
    79621 gtccttaact ttcttttgaa gcaataagaa caaaatgagg aaaagtttaa aattcagctg
    79681 ttgccaacaa ctttcaatag acgaaatctt ctatttcgtt aataataagg aaagaggtga
    79741 agtacatgaa aaaattaatt ggcgtacttg tcgttttagg catatttctc ggcggaagtt
    79801 ttgcagctta tcattatttt tacggcggcg aagcttatta tacaaaaatc acgacgaatg
    79861 gcgaaatgtc agctacccaa gcagataacg gagagaaatt cacgacttat acctacaagc
    79921 aagcggctta taataaagat ggtgaaaaaa aacaggtgac gcttcgcgaa gaaagagaac
    79981 atccattaaa gatgaatgcg tatcttaaac tcaaagtcaa tcctcgtaaa ggtgtattaa
    80041 gctgggaaga aataaaggct tctgaagtgc ctaaaaatgc ggcagaaaaa atcgataatt
    80101 agtaaatggt cttaaaattt tattagataa aaagaggctg ggacagaagc gtttaactcc
    80161 aagaaata
//
LOCUS       DADLIO010000005        78906 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.005, whole genome shotgun sequence.
ACCESSION   DADLIO010000005 DADLIO010000000
VERSION     DADLIO010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 78906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 78906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..78906
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.005"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            <1..386
                     /locus_tag="JOX41_000432"
     CDS             <1..386
                     /locus_tag="JOX41_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAY6448202.1"
                     /translation="QLESNFFRDLNEILSYDPAHSYEELYTRLIDYVYANTFLYRLFI
                     LNHGDISFQKKVKQVIEENYLNIWLYEDKKTIITEEMRFFTTYHVQGCLSVLNRWVES
                     NYKYSKKELLELLQKLNDHIEKIMP"
     gene            complement(691..1005)
                     /locus_tag="JOX41_000433"
                     /pseudo
     CDS             complement(691..1005)
                     /locus_tag="JOX41_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
     gene            complement(1259..2894)
                     /locus_tag="JOX41_000434"
                     /pseudo
     CDS             complement(1259..2894)
                     /locus_tag="JOX41_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294751.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(3217..3696)
                     /gene="rlmH"
                     /locus_tag="JOX41_000435"
     CDS             complement(3217..3696)
                     /gene="rlmH"
                     /locus_tag="JOX41_000435"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HAY6448203.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            4124..5413
                     /locus_tag="JOX41_000436"
     CDS             4124..5413
                     /locus_tag="JOX41_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HAY6448204.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            complement(5452..6057)
                     /locus_tag="JOX41_000437"
     CDS             complement(5452..6057)
                     /locus_tag="JOX41_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HAY6448205.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(6262..6726)
                     /locus_tag="JOX41_000438"
     CDS             complement(6262..6726)
                     /locus_tag="JOX41_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAY6448206.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            complement(6748..7068)
                     /locus_tag="JOX41_000439"
     CDS             complement(6748..7068)
                     /locus_tag="JOX41_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HAY6448207.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            complement(7212..8291)
                     /gene="pepA"
                     /locus_tag="JOX41_000440"
     CDS             complement(7212..8291)
                     /gene="pepA"
                     /locus_tag="JOX41_000440"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HAY6448208.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            8491..8841
                     /locus_tag="JOX41_000441"
     CDS             8491..8841
                     /locus_tag="JOX41_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAY6448209.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            9064..10011
                     /locus_tag="JOX41_000442"
     CDS             9064..10011
                     /locus_tag="JOX41_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAY6448210.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(10068..11486)
                     /gene="pepV"
                     /locus_tag="JOX41_000443"
     CDS             complement(10068..11486)
                     /gene="pepV"
                     /locus_tag="JOX41_000443"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HAY6448211.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            11635..12480
                     /locus_tag="JOX41_000444"
     CDS             11635..12480
                     /locus_tag="JOX41_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HAY6448212.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            12484..12924
                     /locus_tag="JOX41_000445"
     CDS             12484..12924
                     /locus_tag="JOX41_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HAY6448213.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            12974..13168
                     /locus_tag="JOX41_000446"
     CDS             12974..13168
                     /locus_tag="JOX41_000446"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448214.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            13304..13990
                     /locus_tag="JOX41_000447"
     CDS             13304..13990
                     /locus_tag="JOX41_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAY6448215.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IQEALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(14398..15087)
                     /locus_tag="JOX41_000448"
     CDS             complement(14398..15087)
                     /locus_tag="JOX41_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448216.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(15062..17191)
                     /locus_tag="JOX41_000449"
     CDS             complement(15062..17191)
                     /locus_tag="JOX41_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HAY6448217.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLLENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            complement(17239..18576)
                     /locus_tag="JOX41_000450"
     CDS             complement(17239..18576)
                     /locus_tag="JOX41_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HAY6448218.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            complement(18828..19187)
                     /gene="rplT"
                     /locus_tag="JOX41_000451"
     CDS             complement(18828..19187)
                     /gene="rplT"
                     /locus_tag="JOX41_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HAY6448219.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            complement(19240..19440)
                     /gene="rpmI"
                     /locus_tag="JOX41_000452"
     CDS             complement(19240..19440)
                     /gene="rpmI"
                     /locus_tag="JOX41_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HAY6448220.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            complement(19512..20036)
                     /gene="infC"
                     /locus_tag="JOX41_000453"
     CDS             complement(19512..20036)
                     /gene="infC"
                     /locus_tag="JOX41_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HAY6448221.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            20356..20988
                     /locus_tag="JOX41_000454"
     CDS             20356..20988
                     /locus_tag="JOX41_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAY6448222.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(20990..21895)
                     /locus_tag="JOX41_000455"
     CDS             complement(20990..21895)
                     /locus_tag="JOX41_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAY6448223.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(21980..22633)
                     /locus_tag="JOX41_000456"
     CDS             complement(21980..22633)
                     /locus_tag="JOX41_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAY6448224.1"
                     /translation="MIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFYAN
                     PEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEVRV
                     YDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYDYY
                     KELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVAI"
     gene            22955..23899
                     /gene="mvk"
                     /locus_tag="JOX41_000457"
     CDS             22955..23899
                     /gene="mvk"
                     /locus_tag="JOX41_000457"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HAY6448225.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            23892..24869
                     /gene="mvaD"
                     /locus_tag="JOX41_000458"
     CDS             23892..24869
                     /gene="mvaD"
                     /locus_tag="JOX41_000458"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HAY6448226.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            24882..25967
                     /locus_tag="JOX41_000459"
     CDS             24882..25967
                     /locus_tag="JOX41_000459"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HAY6448227.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            25964..27028
                     /locus_tag="JOX41_000460"
     CDS             25964..27028
                     /locus_tag="JOX41_000460"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HAY6448228.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(27277..28080)
                     /locus_tag="JOX41_000461"
     CDS             complement(27277..28080)
                     /locus_tag="JOX41_000461"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HAY6448229.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(28100..28942)
                     /gene="kduI"
                     /locus_tag="JOX41_000462"
     CDS             complement(28100..28942)
                     /gene="kduI"
                     /locus_tag="JOX41_000462"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HAY6448230.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            complement(28958..29965)
                     /locus_tag="JOX41_000463"
     CDS             complement(28958..29965)
                     /locus_tag="JOX41_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HAY6448231.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            complement(29972..30616)
                     /locus_tag="JOX41_000464"
     CDS             complement(29972..30616)
                     /locus_tag="JOX41_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HAY6448232.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            complement(30716..31474)
                     /locus_tag="JOX41_000465"
     CDS             complement(30716..31474)
                     /locus_tag="JOX41_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HAY6448233.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIKTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            complement(31601..32752)
                     /gene="fucO"
                     /locus_tag="JOX41_000466"
     CDS             complement(31601..32752)
                     /gene="fucO"
                     /locus_tag="JOX41_000466"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HAY6448234.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEASVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            complement(32834..33145)
                     /gene="rhaM"
                     /locus_tag="JOX41_000467"
     CDS             complement(32834..33145)
                     /gene="rhaM"
                     /locus_tag="JOX41_000467"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HAY6448235.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            complement(33147..33992)
                     /gene="rhaD"
                     /locus_tag="JOX41_000468"
     CDS             complement(33147..33992)
                     /gene="rhaD"
                     /locus_tag="JOX41_000468"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HAY6448236.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            complement(34006..35262)
                     /gene="rhaA"
                     /locus_tag="JOX41_000469"
     CDS             complement(34006..35262)
                     /gene="rhaA"
                     /locus_tag="JOX41_000469"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HAY6448237.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            complement(35259..36719)
                     /gene="rhaB"
                     /locus_tag="JOX41_000470"
     CDS             complement(35259..36719)
                     /gene="rhaB"
                     /locus_tag="JOX41_000470"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HAY6448238.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            36872..37741
                     /locus_tag="JOX41_000471"
     CDS             36872..37741
                     /locus_tag="JOX41_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAY6448239.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            complement(37867..38766)
                     /locus_tag="JOX41_000472"
     CDS             complement(37867..38766)
                     /locus_tag="JOX41_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAY6448240.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(38931..39755)
                     /locus_tag="JOX41_000473"
     CDS             complement(38931..39755)
                     /locus_tag="JOX41_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAY6448241.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPEIP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            complement(39766..41061)
                     /locus_tag="JOX41_000474"
     CDS             complement(39766..41061)
                     /locus_tag="JOX41_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HAY6448242.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            complement(41077..41556)
                     /locus_tag="JOX41_000475"
     CDS             complement(41077..41556)
                     /locus_tag="JOX41_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HAY6448243.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(41562..42590)
                     /locus_tag="JOX41_000476"
     CDS             complement(41562..42590)
                     /locus_tag="JOX41_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HAY6448244.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLKGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            complement(42607..43713)
                     /locus_tag="JOX41_000477"
     CDS             complement(42607..43713)
                     /locus_tag="JOX41_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HAY6448245.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(43942..46539)
                     /gene="adhE"
                     /locus_tag="JOX41_000478"
                     /gene_synonym="adhC"
     CDS             complement(43942..46539)
                     /gene="adhE"
                     /locus_tag="JOX41_000478"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HAY6448246.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(46844..47224)
                     /gene="yajC"
                     /locus_tag="JOX41_000479"
     CDS             complement(46844..47224)
                     /gene="yajC"
                     /locus_tag="JOX41_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HAY6448247.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(47321..48466)
                     /gene="tgt"
                     /locus_tag="JOX41_000480"
     CDS             complement(47321..48466)
                     /gene="tgt"
                     /locus_tag="JOX41_000480"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010769586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HAY6448248.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            48684..49382
                     /locus_tag="JOX41_000481"
     CDS             48684..49382
                     /locus_tag="JOX41_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HAY6448249.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(49550..52189)
                     /locus_tag="JOX41_000482"
     CDS             complement(49550..52189)
                     /locus_tag="JOX41_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAY6448250.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(52808..53839)
                     /gene="queA"
                     /locus_tag="JOX41_000483"
     CDS             complement(52808..53839)
                     /gene="queA"
                     /locus_tag="JOX41_000483"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HAY6448251.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            54032..55206
                     /locus_tag="JOX41_000484"
                     /pseudo
     CDS             54032..55206
                     /locus_tag="JOX41_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly.; frameshifted; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
     gene            55210..55851
                     /locus_tag="JOX41_000485"
     CDS             55210..55851
                     /locus_tag="JOX41_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAY6448252.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            55848..56765
                     /locus_tag="JOX41_000486"
     CDS             55848..56765
                     /locus_tag="JOX41_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HAY6448253.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYSFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            56762..57433
                     /locus_tag="JOX41_000487"
     CDS             56762..57433
                     /locus_tag="JOX41_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAY6448254.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(57974..58462)
                     /locus_tag="JOX41_000488"
     CDS             complement(57974..58462)
                     /locus_tag="JOX41_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HAY6448255.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(58663..58929)
                     /locus_tag="JOX41_000489"
     CDS             complement(58663..58929)
                     /locus_tag="JOX41_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAY6448256.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(58929..59192)
                     /locus_tag="JOX41_000490"
     CDS             complement(58929..59192)
                     /locus_tag="JOX41_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAY6448257.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            complement(59185..59457)
                     /locus_tag="JOX41_000491"
     CDS             complement(59185..59457)
                     /locus_tag="JOX41_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448258.1"
                     /translation="MYWCCCIDSQALDSTFAKDDTLLPITLRLATASRKGVRSERGQR
                     SSLKRGLFLYVKKRKSLLNLSALLYFFDVLNQVRYNYIRKRRRDNG"
     gene            59668..59853
                     /locus_tag="JOX41_000492"
     CDS             59668..59853
                     /locus_tag="JOX41_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAY6448259.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(59995..61818)
                     /locus_tag="JOX41_000493"
     CDS             complement(59995..61818)
                     /locus_tag="JOX41_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HAY6448260.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(62416..65121)
                     /locus_tag="JOX41_000494"
     CDS             complement(62416..65121)
                     /locus_tag="JOX41_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HAY6448261.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(65427..66374)
                     /locus_tag="JOX41_000495"
     CDS             complement(65427..66374)
                     /locus_tag="JOX41_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HAY6448262.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            66564..66833
                     /gene="rpsN"
                     /locus_tag="JOX41_000496"
     CDS             66564..66833
                     /gene="rpsN"
                     /locus_tag="JOX41_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HAY6448263.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(67009..67371)
                     /locus_tag="JOX41_000497"
     CDS             complement(67009..67371)
                     /locus_tag="JOX41_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAY6448264.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(67382..68503)
                     /locus_tag="JOX41_000498"
     CDS             complement(67382..68503)
                     /locus_tag="JOX41_000498"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HAY6448265.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(68519..68869)
                     /locus_tag="JOX41_000499"
     CDS             complement(68519..68869)
                     /locus_tag="JOX41_000499"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HAY6448266.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(68999..70510)
                     /locus_tag="JOX41_000500"
     CDS             complement(68999..70510)
                     /locus_tag="JOX41_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAY6448267.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(70832..72184)
                     /locus_tag="JOX41_000501"
     CDS             complement(70832..72184)
                     /locus_tag="JOX41_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HAY6448268.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(72337..73413)
                     /locus_tag="JOX41_000502"
     CDS             complement(72337..73413)
                     /locus_tag="JOX41_000502"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HAY6448269.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            73609..75354
                     /locus_tag="JOX41_000503"
     CDS             73609..75354
                     /locus_tag="JOX41_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HAY6448270.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(75634..76071)
                     /locus_tag="JOX41_000504"
     CDS             complement(75634..76071)
                     /locus_tag="JOX41_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HAY6448271.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(76055..77428)
                     /locus_tag="JOX41_000505"
     CDS             complement(76055..77428)
                     /locus_tag="JOX41_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448272.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(77750..78238)
                     /locus_tag="JOX41_000506"
     CDS             complement(77750..78238)
                     /locus_tag="JOX41_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAY6448273.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEVFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(78260..78862)
                     /locus_tag="JOX41_000507"
     CDS             complement(78260..78862)
                     /locus_tag="JOX41_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAY6448274.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT        22764 a        16768 c        14364 g        25010 t
ORIGIN      
        1 atcaattaga aagcaacttt tttcgggatc taaatgaaat tctctcttat gatccagccc
       61 atagctatga ggaactatac actcgcttga ttgactatgt ttacgcaaat acttttttat
      121 atcgcttatt tatcctcaac catggtgata tttcgtttca gaagaaagtt aaacaagtta
      181 ttgaagaaaa ctatctgaac atatggctat atgaagacaa gaaaacgatt atcacagaag
      241 aaatgagatt ctttactacg taccacgtcc aaggttgtct atccgttctc aatcggtggg
      301 tagaaagcaa ttacaagtac tccaaaaaag aattattaga actcttacag aaactgaatg
      361 atcacataga gaaaatcatg ccttgaataa aaacatacta agcttagtta agaagaaccg
      421 taaccttctc gtataacaac tgaatcttat ttagccaaat tgtttactga agattttttg
      481 agtaaaattt ctataattcc tacttattga aaagtagttt gtagtgctgc ttctccctct
      541 ctaagtgata tatcttgttg taccaatcaa attcacctca tcattaataa attactttta
      601 ggctaattta ttacaactta taggttgaag ctgtaaccaa tttatagtca tattatattt
      661 ttatcatcca gtttattgaa ttcttctcgt ttacctcaat tcattttcaa ggggaatcag
      721 ctcatcatct aacattttac gccatgctcg cttcatttct tgtgggtatt taaatggttt
      781 cgcttctgga tgtttggctt tatatccttc gtaatcctta ctgttgataa ttgctttcat
      841 attaggaatt ggatcttcac ctggcatata ttgcagatta gaagcatgta attttttctc
      901 agaaacaaac cactcattgg aaaagacatg aatcaaatca tcacttactt gtgtaaaata
      961 gcgacgttta atgacaaaga tatcttcatt gctatctagt gtaccttcat ttctttgtgc
     1021 ttaaattcaa agataatttt ctcaataaag atttttgatt ccagtaagat tcctttactc
     1081 cttttacaac atagcgttgt cctttgtttt gaaacatctt cttcccctct ttgccattaa
     1141 aaatagccca attctctata aagaagatta agcttcatta ttataatata aagtttaaat
     1201 ttggtttatt acttactttt tcttattctc tagtaagcta atattgaaaa aaatgtaatc
     1261 agatcattat ttttatatgt tgtaacttcc tgataagaaa actaattaaa agaaagaggt
     1321 aactacataa actaattaaa aaagctaact tcatagttgg aggataaatg gaagaaactt
     1381 caatgattgt ttctccttgt gttccttcaa tcgacactag tcctattatc aatctctctt
     1441 ttttgtccat ttacttttgc gactgttccc caataatcaa atacaggaag cgttattttt
     1501 tgtcctttag attcatgtac tgtatagact attttcgaat ccatcacttg ataaggcata
     1561 gtatgccatt ccttgccaat tcttacttca tgattctgca aatgttcttt gtattgtaat
     1621 gcttccgtgg gtgcatagtc ataaagtcct ccgggaagga gtgtcgtgta acgaataaga
     1681 ttttcttgat tcattaccaa gtgatctctc tgagtgacaa ctttatgttc atagtttgct
     1741 tttgttgcag cagatacagc caacagtaat aaaacaattg ccgttatatt aactactttt
     1801 ctttgcttag ctgatgtgct cttcatgaaa acgaacgata aaatcaacga gccaaacagt
     1861 acttgaaagc ctaagattcg ccaaggaaat tgaatcattt gaatgggtgt attttgtaat
     1921 aaagaccatg gaaaaaattt ggtggataag agccaagaga ctaccgcact aaggtaaatc
     1981 actttttctt tgcgattaaa tcctttaaaa aagaagagtg gacagatcaa agaaataata
     2041 ccaatgattc ctaccgtaaa ggttgtcagg tcattattca tcgcaccaat caaactatcc
     2101 gagacattta atgcttggtg ttgtaaggtc gttttatctg gctcattaat cgattgaacc
     2161 atgatttgtc ggaacatcgg ataccaaaag tatgctgtta aaagaatcgt cattcctact
     2221 gcctttgaca actccacaat caaccggatg ctttcttttt ttcttgtttc acttactaca
     2281 aagccgccta agactagtaa gccaacggct attacactca taaaagtgga aagaacatgt
     2341 gtataaatga gtaagctcat actgactgct aatggaattg cacatggctt tttctcataa
     2401 atcagtgcgt aagcataata cataactatc ggtataaccg taagtgcaat cgcttcagca
     2461 atagcagaac gatgataaat atcaatcgta cggtacccat aaaatgtata taaacagcta
     2521 aatataaaag ccgcatcgat tctttttaaa aattttagtc cataatgaaa catcagcatg
     2581 atagtacaaa cattcaatag ccaaacatat aagatataac taacgattaa attattactt
     2641 atccaataaa aaatgactgc cggaaaaaag gtcaagtagg gataaaaata attcactccg
     2701 ctcccataat gattaaacgt cgtaaaattg attggaccag aaaaaattga agataaccct
     2761 ttgactctag caaaatggaa ggcaatatcc cccgatgtag aaatagtatg aacatttcta
     2821 aaataattga ttgaataaag tccagcaata attgctagga gaatggacaa tattattttt
     2881 ttctttactt gcattactta attatatact cctttcatgg attgctttat ctagtataac
     2941 ttaaatttta aataaatcgt tatttatttt tactctcact taaaaaagca ctaaaattat
     3001 aagagaggga ggtaatggtc tgaacaccaa gaattgttcc aacatcgaat tgcttaacta
     3061 atgagttcaa agcttaatta tgtggctctt atatttaccg agcgtggatt gcgatctctt
     3121 tagcgaaaca aacatctttc ataaaaaaaa cagccatatc cgctttcttg gatatgacta
     3181 tttactacta ctttactatc tttcattctt cttgtctcac ttatgataag gcgcccccgc
     3241 attgatccgg aaggcacggt agatttgctc gacaaggatc agacgcatca attgatgtgg
     3301 atacgtcatt tttccaaaag agatctgagc attgcttctt ttcatgacgg cttcgctgag
     3361 tcctaaagag ccgccgataa caaaaacaag gtggcttttt ccttggatac ctaattggtc
     3421 gatttgttta gcaaaagatt cacttgtagg atttttccct tcaattgcta aggcatagac
     3481 gtattcttgt tctttgattt tcgctaagat ccgttcccct tctttttctt ttacttgtct
     3541 catttgcgct tcgcttaaat tctccggggc tttttcgtca ggaacttcga tcaattcgat
     3601 ttttgcatag gcattcagcc gtttgacata ctcattgata ccttggatca ggtatttttc
     3661 ttttaatttt cctactgaga taattttgat attcatgttt tctctccttt ggtcttcatg
     3721 ctcactttgt ttattataat caattttttc gtctatatgt ttattttggc tatttttgtt
     3781 aaaaagattt ccccaacagt tatgcacaac atccacaggt ttatccacag aaaacagtgt
     3841 tattttacct tatttcatca cattcattag gcaaacatac gttttataag aatttatcca
     3901 ctttatacac aggctgtgga tatgttttat cccttatttt tccaatccta tccgcgtagt
     3961 tttacacagt atctgtggaa aaagaaaatc aaatattttc atctgaaaac aatgattttt
     4021 cctaaagttt ttcataaaaa gttcacagtc tcaaagtaga ctaaagtcaa caaataagac
     4081 tatactaaca gtagataaat gaatgtaatt ggaggaggaa cacatggata gaaaaaatgt
     4141 gacaccaaag atgaaaaaaa gtaaaaataa tagcctctgg cgtaagttag gtctggggct
     4201 tgttggaggg atcgttggag gactactgac agctggcatt ttttatgcag cgatgggcac
     4261 tggcaacaat agttctactg ctacaagcgg caatcagaat tctgccggtg aaacagttgt
     4321 ggaaaatgtc aaagtcaatg tagattctga tatcaccaaa gcggtagata aagttcaaga
     4381 cgctgtcgtt tctgttatca acttacaaag tcaaaaccaa tcaagcggtt ttggcggact
     4441 attcgggcag caagaagaaa gtagcagctc agatgatagt aatttggaag cttatagtga
     4501 aggaagcggc gtgatctaca aaaaagacgg gaatactgct tatgtagtca cgaataatca
     4561 cgtagtagat ggccagcaag gtcttgaagt cttgatgaaa gacggtacga aggtaaaagc
     4621 tgaattagtt ggaacagatg cttattcaga tttagcggtg ttgaagatca attcagacaa
     4681 agtcgaaaca gttgcctctt ttggtgactc aagtgctctg aaggttggtg agcctgcgat
     4741 tgcgattggt tccccactag gatctgaata tgcaaattct gtcacttcag gaatcatttc
     4801 ttccttgaac cgacaagtga caagtacgaa tgaatcgaac gaaacagtca atatcaatgc
     4861 gatccaaaca gatgcagcaa tcaaccctgg aaattctggt ggtcctttag ttaatatcga
     4921 aggacaagtt atcggtatca actcaagtaa gatcgcaagt acttctgaat ctacttctaa
     4981 tgtaagcgta gaaggaatgg gatttgctat tccaagtaac gatgtagtga atatcatcaa
     5041 tcaactggaa aaagacggaa aagtgacacg tccagctcta ggtatcacaa tggtcgactt
     5101 atctgccgtt tctactcagc aacaagaaca aatcttgaag attccttcat ctgtaactaa
     5161 cggtgtcatc gtgacaaatg tccaaacagc tacaccggct gaaaaagctg gattgaaaca
     5221 atacgacgtc attactaaga tcgatgacaa agaagtttct tctggtgtag aacttcaatc
     5281 tgctttgtat aagaaaaaag tgggagattc tgtcaaaatc acttactatg aaggctcgaa
     5341 agaaaaaaca actactgttg aattgacgat cgatcaatcg gcattaaaac aaaatcaaaa
     5401 tagtgaaaat taataaaaaa gaggttgtga caaagacttg tcacaacctc tttattttgg
     5461 aaatgcttct ccgactacgg catcctcagg caatactaag attccttttt ttgctggagc
     5521 atttggcaaa tgcaattcac gagcggaaca gatcattcca tagctatcta cccctcgcaa
     5581 agttcctggc cagatcatca ttccatctgg catcatagct cctggttttg caacgacaac
     5641 tttttgtcca gcttcgatat tgggtgcacc gcaaacgatt tgcaatactg taccattgtc
     5701 tacttctgtc tcagtaatcg ataaatggtc agaatcagga tgtgggacgc atgtttttac
     5761 gtacccgaca acgatcttcg gttcatgatc agcttcaagc tgttcttcga atcctgcttc
     5821 tttgatcaat cgattcaatt tcgctaattc ctcatctgtt aagcttactt ggccgttccc
     5881 ttcgattgtt agatgatcgg agatatggaa aaagttccaa gcaacaactt gaccttgttc
     5941 atctttgatc cgagcaacat tccatttgcg ttcaacagtg ttttctgttc ctttatcgtc
     6001 ggctataata accatcaagg tgtctccgac gtgtgctttg ttataagcaa aaatcatgtt
     6061 ctttcctcca ttatcctttg ctgagattta tcttaacaaa aaattgcatt cactgcatga
     6121 aatttttttc atgctttatt tccgaagaag cctcttctgg aacaccattt attcgtaaca
     6181 agggactgtg acaagacttt tgtcacagtc cctttactgt tttagttaat tgattaaaaa
     6241 ggtcgtacaa gttccacttg cttaattact tggctgttct tcttcgtcag aaacgatcaa
     6301 gacatcacaa ggtgaatgac gtatcacgta gctggctaca cttcctgtca taaagcgttc
     6361 gactgcattt agacctgact gcccaaccat gattagatcg atctcatatt tttttggcaa
     6421 tttgactgcc atggattcac gaacagaacc atatgcaata attccttcta tatttgtgta
     6481 atcaacagat ttcccatatt ctttacattc ttcgatcatt tccttggctg tttcagtttg
     6541 ctgatcgact agattttgat caataggtgc atagcccata aagttataaa attgctgatc
     6601 gattacgttt gctacatata ctttcccatt attacggcga gccacttcta ccgctttttt
     6661 gaaagcagca agtgcttgtt cactaccgtc gatacctact aaaatattct tatattcttg
     6721 attcatcttg acccctccta acagatgtca gccttttgtt acactttcta ggaacgattc
     6781 gatttcctgt tttgttttac gatctttatt cactagacga cctaattctt ttccgtcttg
     6841 gatcacgaca aaacttggga taccaaaaat gttccattca gcggctacat ctatgtactt
     6901 gtcacggtct acttcaataa attgccaatc agaaaagtca ttttcaattt caggcatttg
     6961 cggtttgata aaacggcagt ctccgcacca gccggcagta aagaaaaata cactctttcc
     7021 agtttctacg tagcctgcta attcttctaa actatttggg ataatcattc tttgtcctct
     7081 actttctgtt tatgtatttt tcaattaaat tatacacctt tctttcgaac taacaaacat
     7141 tgatcctctt tttataaaaa aaatctggca aaaagcaatc ttttgccaga ttttatagtt
     7201 tcactatcgc attattttcc gtatacgatc gtatttactg ttgatttatc caaacctttc
     7261 agtgtttgaa tcaacatttc tcgtgcagct tcaaaatcgc gaatactgaa catcgtttga
     7321 tgcgtatgga tataacgtcc cactacgcca atcactgtac ttgggattcc ttcgttttgt
     7381 gtatgagcag cacctgcatc tgtaccgcct tttgaaacaa agtattgata agggatattg
     7441 tttgtttcag cgatatccag caagtactcg cgcaaacgag gaagcatgat caaacctgga
     7501 tcttggatac gcatcaatgt accttctcct aaatgtccga atgtgccatt tttcgtcact
     7561 gtatcatctg ctgcagagca gtctactgca aagaacagat ctggcttgaa tttattgaca
     7621 gaagctttag aaccacgcaa gcctacttct tcctggacat tcgcgcctgc aatcaatgta
     7681 tgacctaatg tttcattttg caacgcttct aaagcttcta ataccattgt acagccatag
     7741 cggttgtccc atgatttact gataatattc tttccgttgg ctgttttgat cgtttcagcg
     7801 taaggaacga ttgtgtctcc tggaaggaca ccgtaactca ttgcctcttc tcttgattca
     7861 aacccagcat cgaacaaaat atcggttact tctactgatt tttgtccgct tgttcctcgc
     7921 aataaatgtg ggggaacgga agaagaaata catggataat tcttaccagt agaggtttta
     7981 agtgtaaaac gctgagcaga aacaacgtaa ggattccagc cgcctagagg tacgacttta
     8041 aaaagcccgt tttcttggat ttgtgtcagc atgaatccga cttcatccat atgtgctgcg
     8101 accattacac ggggtgcatc cgcttcttca tgatggcgca gaccaaaaat gccgcccaaa
     8161 ccatctaact gtaactcatc taccagcggt tccatatgac tttccatata agcgcgaaca
     8221 tcttgttcaa aaccgcttgt tccttgtaat tctgttaact ctttgattcg ttgaaatgtt
     8281 ttttcttcca tatgctattc gtctaaattt cagactaaac tcctctcaga cttatattga
     8341 tctgcggata aaatatgatt ttttctgcag accgatcgta tttattatag cttatttttt
     8401 ctggtagcgg ttatttattt caaagaaaat atgagagtgt ggtaaaataa gcacaaggag
     8461 taacaagtga gaagaaggag gtatgtccac atgtatgaag aaagcgaact aagctatttt
     8521 aaaggcgggt tagcagttgg aatcggtcta ggattattga gcggggtagc ttcaacgatt
     8581 tggtatcatc gcaaaaaagt attgtcagca gaccaagtac ttgaaaatat caagtcatct
     8641 tttctaaaag aaggtgcaat cgaaggttct tggatctctt ttgaaaagga acctattagg
     8701 aaattcgccg ttcggtcgag tgcttatcgg ggaggtcttt ctcgaataga agatggcgaa
     8761 actgtttatt atgaattttt agcagatgct catacaggaa ccgtattaga aatttcaaga
     8821 aaaaaaggtg caacagatta atacgtcaaa aaagtgagag aacgaatacg cacccactat
     8881 tcaaaagaga ggtatcatgt ccttcttttg tagtgggtgg ttttttagat agagctttcc
     8941 aaacatatat tccagtattt tctttttaaa taaatgatat ttagcgggaa aaactagcat
     9001 ttcctttgat tatgaggtat ttttaattta gcttttgttt tctatagtta aggagagtga
     9061 aaaatggaac aacaagaaaa aattgctgtt ctgattcctt gttacaatga ggaagcaaca
     9121 atttcaacag tcattgcaga ctttaaacga gaattaccag aagcagatat ttatgtctat
     9181 gataataatt cgaccgatcg aacatacgaa ttggccgttc aaggtggagc aatcgtaaaa
     9241 aaagaacctc gtcaaggaaa aggaaatgtg atccgccaaa tgttctttga tatcgatgcc
     9301 gactattatt taatggtaga tggcgatgat acttatcctg cagaagctgt acatggtttg
     9361 ctcgagaaat tacgttctgg tgaagcagat atggtcattg gtgatcgcct atcaaatgga
     9421 acctactttg atgagaataa gagacctttc cacgattttg gaaataacct tgttagaaat
     9481 acaattacta gaatgtataa aacaaaaatt cttgatgtca tgaccggcta tcgaggattc
     9541 aatcgtatct ttgtcaaaag ttttcctatt atgagttctg gttttcaaat cgaaacggaa
     9601 ttgacgatcc atgctttaga taaaaaattc aagttcgttg aaatcccaat cgattatcgt
     9661 gatcgtcctg aaggcagcga atcaaaattg aatacattct ctgacggatt caaagtgatc
     9721 atgatgatta ttaaaatgtt taaagattat aagcctttgc ttttctttgg gatttggacc
     9781 atcttcttct ttttatttgg attggtcacg gggattcctg tgattcgcga atatatgctg
     9841 acaagcttta ttacacgcat cccttctgcg attttaagta ctggattgat gactttagca
     9901 cttctttcat tagtaacagg gttgattttg gatacagtcg tcacgaacgc taagaaagaa
     9961 tatgaattga atctatatca tgtttatcat gaataccaca gtagaaagta aaaaaaggat
    10021 caagactgca aaaataattt gcaattcttg atcctctttt taattaatta tttcgccaaa
    10081 cgatagatgg catctgcata gattgctgtt gctctgaaca agtcatcaag actcataaat
    10141 tcgtttgctt gatgcattgt atcagtatat cctgggaaca tcgctccata agcaacgcca
    10201 cgtttcaaca aacgtccgta agttccgcca ccgatgattt gttcgtagcc tttttctcca
    10261 gtgtggtctt catagacttg caataatgta gccaccaatg gatcatccat tggtacgtaa
    10321 tgtggttcca ttacgcgagc acctcgagta actgttgcgc cttcttgccc cactgtttgt
    10381 tcgatgtcac tttgcaatcc gtctactgtt acaccttttg gaaaacggaa attcatattg
    10441 atgaagttcg cttcctctgt accattttct tcaaaagcaa atagtccagc attcattgtc
    10501 aatttgccca ttttttcatc ttcataagcg actcctagtt tttctccata aaaatcttca
    10561 tggacataag cagctgctac atggataaat tgtttagcag atcctaggaa ttcatagtta
    10621 tctaagaaca atgccaagaa agaacctgca ttgataccag attgtgggct tgcaccatgt
    10681 gcgcctttac caactaattc gatttttaca tacgtattgt ccgcttcaat cgttccgctt
    10741 actggatttg cttcgatgaa ttggtaaaat gcttcttcca tcgcgatagc tgcatctgca
    10801 cttggtactt gaagtgctgc agttgctgtt cctggcacca tattttcgcg aagtccggaa
    10861 acaaaagatt tcaagacata atctcctgca ttgtcgcctt tgaagcgtaa agctaaagaa
    10921 acatttcctt tttcaccatt gatgattggg aattcagcat ctggtgagaa accaaaatct
    10981 ggttcttctt catgttcgaa ataataagcc atatcgcccc agccgctttc ttcatcgctg
    11041 ccgactacga agcgaacttt ttttgatagt ttcaagtcaa gttctttaat gatcttcatc
    11101 gcatagtaag ctgccatact tggacctttg tcatcgcttg atccgcgtgc aaagatcttt
    11161 ccatccttga ttactggttc ataaggatct gtgtcccagc catctcctgc aggaacgaca
    11221 tccatgtgtc caaatatccc tagcgtttcg tctccttcgc caagatcaat atgccctgca
    11281 tagttatcga cattttttac tttaaatcca tcacgttcgc cataagctaa catatgtttc
    11341 aatgcgtcgc gaggtccagg tccaaatggt gcatctggtg ttacttttga gtcatcgcgc
    11401 tcgctgttga cacgtaaaag atttttcaag tcttcaagca agtcttcttt acgtgcttct
    11461 acttcttttt gccaatcaat tgtcataaag ttaatcctcc acttatttaa gtcttcgtgt
    11521 tcatgatacc acaaattaca gaaaaaaata gttcaaaaaa tctgacaatt ccttttctta
    11581 tctgtttttc tctaaaaaaa atatacgcta taatgagtaa aaggaggttt ttagatgctg
    11641 ataaacgaac aactagtgaa aagagtcatc acacctcgtc caaaaatttc acataaagga
    11701 acatttggac gtatcgtttt gattggcggc aatgaacaat atggcggagc aatcattatg
    11761 agtgctttag ctgccgtaca cagcggagcg ggtctcacga ctgtagtaac tgatgaaaaa
    11821 aatcggagtg ctcttcacag tcatctgcca gaagcaatga ttgtagtttg gacggatact
    11881 gaccagtttc tttccgtaat aaagcaagca gatgtactct tgattggtcc cggattgggt
    11941 acttcttcta agagtttgga acgtttcaaa caagtactag aaaaccaatc aaaagaacaa
    12001 tggctggtga ttgatggctc tgctttaagt ttacttgctg ctaatcatct tttgctaccc
    12061 tatcccgaac aaactgtact tacacctcat caaatggagt ggcaacggtt gagttctcta
    12121 ccgatacaag aacaacggga taaagaaaac aaaaagaagc aacaggaaat cggtgctgtg
    12181 ctcgttttga aaagtcatga gacaaaaatt tatggtcacc agcacttcta caccaatcct
    12241 ttaggttctg ctgctatggc aacgggcggc atgggtgaca ctttagctgg gatgatcaca
    12301 ggatttttag cccagtttcc tcaaaatgac caaacgattg cagcagctat ttatcttcat
    12361 agtttcattg gagaccagct ggcaaaagaa caatatattg ttttgccgac acaaatcagc
    12421 gaagcacttc cgaaatggat gaattatttt tgtaaaaaat caatggaaaa cgaggcatga
    12481 gtcatggaga aatttacagg ttatgtgcga gaaccttttt attatgaaac agatcaaatg
    12541 gggattattc atcacagcaa ttatatccgc tggtttgaag aggctcgggt agccttattg
    12601 gtacatctag ggtttcccta taaaaaaatc gaagaatctg ggatcatcat ccccgttctg
    12661 gaagtaaatt gcagctataa agaaatgatc cattacggag aaaaagtgag catccatcca
    12721 actatccaaa agtatacggg gacacggttg gattttagct acgaaattgt gggaactgaa
    12781 gacaaaaaat taaaaactac tggcagtagt aaacactgtt ttttactttc tgattcgcaa
    12841 cgattagtga agctgagcaa agtcaatccg gagttagatc agttattcca agcgtacgct
    12901 tctttggatg atgtaaattc ttaataaaga ccgtctaagc atttttcttg tattgtgtcg
    12961 agtagttcgt ataatgaaaa gaaaaaagca ggtgatcccc atgtatgtcg ttaaagtaat
    13021 gcacggttac atcgataaaa ctggctgtcg cactcgggaa aaaaacttag acaatctgct
    13081 cattttcaaa gacaaaaaag aatccgaagc ttttgctaaa agaatcggcg gtcgtgtcaa
    13141 accgatccaa gaggtacgac cagattgatt caatattttt cttttcgagg ctctaatagg
    13201 catgcctatc agggcttttt ttgcagactg tgtttttatg cccacacgat ttgtaagcga
    13261 tttatgttat aatagattat atctgcatag aaaggaaggt taaatggtta tcaataattt
    13321 gcaacagcaa gcttatgaat ctatacgtaa acaaatcatt tattccgagt tagcacctgg
    13381 aagtaaaatc tccgataaag tgttagaaga acaactagct atcgggcgta caccgattca
    13441 agaagcactg atccaactgc gcaatcaaga gcttgtaaaa accattccac agtccggcac
    13501 ttatgtttca aaaatcgata tccgatctgc ttcattagcc cgttatacgc gggaaaagtt
    13561 ggaaaaaccg atcctgcaag aatgcagtgc gaaaatgacc aagcaagatc aagctaaact
    13621 agaaaaaata ctagaacaaa ccgatcaggc agtaatcgct caaaataaaa aagctttttt
    13681 tgatttggat actgattttc accgaacttg ttatgaaatt gctggaaaac gagaaatttg
    13741 ggattggcta gaaagttata gtacgcactt gaaccgtttc agatggttac gtttgacgat
    13801 ttcagaatta gactggggtc gagtattaga tgaacatcag acaatgcttc aatcaatgat
    13861 tgatcataac tttgatgaag tcggatttct ttgcacgatg catttacata tgattatcga
    13921 ggagcaagaa tacgtgattc ataattaccc cgattatttt gaagatattc aggacagacc
    13981 catcaaataa gaggttttgg aatcagcgtt ttgacctgag tattagagaa agaaacggca
    14041 aaatagttcc tcatattttg ccgttttttt tgagctaata ccgagggtca gctgattgca
    14101 caccgtttat tgagaggttg tgaaaaagct gccctgcatc aagtaataag aacagccaag
    14161 taaaaatagc ttcttatgtt tttaacttgg ctggacttat taccgcagat gcaagctttt
    14221 gaacaccgtt ttccaagagg tcgtgagcct gccgttcatc tccgagtcac aaggaacaat
    14281 ttcaaaaaac agcttctcat gtttgttgaa tattttgact tgtgaccgag gagttgacag
    14341 gagaacatcg tttattcgga aaaaaaggac tgtgacacga cttttgtcac agtctcttta
    14401 tttgtaatct aaatcatact ccgtacatct tttttctatt ttttttattt cttctaagat
    14461 cccttggcta cgaatttcat tatatggcca aagtaagact gcctctaata cataaggcga
    14521 aaaatcgctt tgattcatct cttttgaaaa actcatcgct gctatctcgc tcaatgcacg
    14581 aatgtttgat tgatgtgtat aaaaaggcaa ccgccacagc acaatttttt cgctttgcgt
    14641 ataaattccc ttaacagaag cttcgatgtg gtgaaatagt tcatgtccaa taatcaaagc
    14701 ttgcgctgtt tctttagaga tcgaagctag tcctgaacat tttaattttt ctaacggctc
    14761 cgtcatcaat cgaatccctt catcttctgc ataagttgca aaagtgattc gttcgtttat
    14821 ttgctctgat tcacaggaaa cgattggaac agccatttgt tcacaaattt ctcctacatc
    14881 ggcaaaaggg tacttttttt tgatgctaca tgccgtttcg ataccacaat cgattgattg
    14941 ttgtataaga attttctgct tggacaaagg aatctttttc caaaataaat ctcgccgaaa
    15001 ctggtagaat ccccaaattt cttcggggat ctgttgtaat tcgtttagta actcttctaa
    15061 cttatgtttg tttgatattt ccggcaacga cgatcacttc ttcctccggt tccatagtag
    15121 atacttccag atccatcaaa agctgtagtt gttccagatc cgtcgctgta aaatcagaga
    15181 ctcttgctcc taagcagaga taaaattctg gtcgggcaat caattcagtt tgataaactg
    15241 ccatatcttc ccaaagttgt tcgacagctg tcatataatt ggctgcagtt gttttcatac
    15301 atgaagcatg tccacgttgg accttgataa atcctttttg atcgatgatc cgaagacttc
    15361 cagcattttt tgaacgattc tgttcgccgc atacataaaa gaaaggtgta ttttccaata
    15421 agcaaacttc atttttattt aatcgcatat cctctgcagc aagctctagt gcttcttctg
    15481 ttgtgatctc cttggttaga tcggttgctt tcacttccgt agaaccagta gcgatagccg
    15541 ttacttttga agtctgtgga tcgatttcta cgtggacttc gatcgattct ggtgtagcgc
    15601 ctgattcaat cgctttattc atcgcttcat ttttcaacga tcgtatatct tctttacttg
    15661 gcgaagggat gatacgttct acaacatctc ggaccattgc aagtgctaca ccaatagaag
    15721 aaatcacttc ggcgttttca ggaatcgaat atttcacacc cattttatta ctaaagtaag
    15781 taatcaatga ggcagcgccg ccccctacac ctacaagaga aatctgatct ttctccaagt
    15841 gatacttgtc tgccaattct aaaatcaccg gttcaatctt agcataggat ttttccatga
    15901 tctgttctgc gatgtcttca accgtcgtat gacaataatc agctaatgct tggatggctt
    15961 ttcgtgcaga tgggacattt ccataagaaa aatgttcttc ttgcactaat ccaaggacat
    16021 tggctgcaca tgtatttgta atagtcactt cttctccgtc ttccatcact accttgacgt
    16081 aatcagcagg gtctccttct ttaggagaga aaaattcaac cttaggacct ttgatttttt
    16141 ctgtctccgt aaatactgca taatctagac cggcaatatg tgcagaacgt ggaccgacat
    16201 cgatgattcc tgactgatta gcccgtacca tcgaaccgcc tgccacacct agaacccgaa
    16261 catctaatga agagatatat gttgggtggc cacctacaat tgaataatcg attgctggac
    16321 gtccattttt aatgaccccg atattggttg ttgttccgcc tacttcaaaa taaacaccat
    16381 tagacgctct caagtacatc aaagagccca tgactgatgc tgctggaccg gaaagcatgg
    16441 ttaaaacagg tcgttttttc atttcattga tttccattac tccgccgtct ccgcgcataa
    16501 tcatcaaaga aacattgacc cctgcttctc gtacggaatc ttctgtagag gttgccgtat
    16561 ctagcatttt tggtaaaata gatgcattga ttgctgctgt ccgagttctt cttgtcaatc
    16621 catataattt tgtgatgtca gaagccatcg ttgtagggat cgattttacc gatgctgctt
    16681 cataaacaac tcgttctggt tccccattat ctactccaaa tgccatagaa gaaaccaaga
    16741 cctccgctct ttctctttct aaagaagaaa tcgtttctga aacacggtct acatttaagt
    16801 gtttgacagg taagaatgca ttgacaatct ctattttttt cttattccct aaatcgatat
    16861 cgttcaatct agtttgtcgt tttgctaaaa aaccttctaa tccacctttt gccatcccga
    16921 ttacgccgac ttttgctacg tctccttcaa tcagtgcatt agtcgcttgt gtggtagaat
    16981 gtgcaacaaa cacaacatct tctggactga tattattttc cagcaaacaa ttttgaaaag
    17041 actgaacgac acctgcggct actccacgga catcatcgtg ggttgttttc actgaagatt
    17101 ttccgatgat ttcgtgcgtc gcattatcga ttgcgactgc tttcgtatgt gtaccgccaa
    17161 catcaattcc cattcgcaca aaacgtttca ttttcttttc ctccattcat ctaatcgttt
    17221 ttatcgacgt tttgtttact aggcgttccc gtacaataag aacgtgatca ggcataagat
    17281 cgctccgatg atccaaccag ttgggatgga tttcttcata tattctcgag aagttacttt
    17341 tgtataacct aatccccaag caacccaaga ttgtgtaata tctaaatgct gaggagcaat
    17401 cgttgtgatt gcaaataacg ggaacaaaaa ggctggcgac atcgttggat taacagctaa
    17461 tacgacagct aaaatagctg agcctgaacc gactagattc attggaccgc ggaaaaatcc
    17521 tagtggtgtc aatatagcaa atacgattgc caagactaat ggtgattgcg gtatccaatc
    17581 tccaaaaata gctgaaaaat aaggagaagc atacgcagct gaattattga acatcgctaa
    17641 ggtcatcaag aaaccaacca ttggcgcaac atctactgcg ccatctgtaa ataatttcgc
    17701 aaactgacga cagatttctt tataacctcc gcgcaatttt ccagtaaaca gcaatgccca
    17761 gatacctgct agaataaaac ctaagatgat tggaagatct aaaagaacga cccctaaaac
    17821 tggtaataat acggctaacc atgagatcat tggtgcgtcg ccaccttcag ctggtacgtt
    17881 tgctgccatt gcatagcgtt tctttttgtt cattgatata ttagcgaccg ttagtaccac
    17941 aactaagctt acaatcatcc caatcatacc aatttggaaa tagtcattat aagtatagct
    18001 ttcagccgct ggattgaaac cagcataaat cgtttgatat tgtttgaaat tgacgatatt
    18061 agcaaagatt ccagccataa tcgagcccat aaatgagaac agtgcaaccg gtactgaaat
    18121 acctaatgac atcaagattg gcaacacaat aactgcaata gaaatcactg gtccgattcc
    18181 tgtcatcgac atgaatataa cagcggttac aatacatagt aagctcatcg tgattcttgg
    18241 cttgtcccct ccaagttcaa ctacctttcg aatcagggta gctgcgattc cgctatctac
    18301 tagaacacgc ccgaaaaagg caccaaagaa gacatttacc aagatcgatt tggcgtactc
    18361 agctggcccc gtcgtataga tatgcgtcaa cacatcaatt actccttgcc cttccatcgc
    18421 cgggtttggt gaaaacgtgt ttccgactag cgctaatccc atccatacag tagccatgat
    18481 ggcaaagccg accatcaagt tgtagccttt tacacagtac cagaccatga aaaagaatga
    18541 gataactaac aaaataccaa taataatatc actcatgtta ttcctccgtc cattttgttt
    18601 ttctgataag caaactaata tatcagtcaa actcattcta acttatgtag ttagcgcttt
    18661 cattaaaggg tgaccataaa tgttcagttt tcaattaaaa aaccttaatt atgctatttt
    18721 agacttatac gttattgtcc tgtttcattt gatggaggat tgtaaataaa aaaagaggaa
    18781 agaacataac ttttcgttat cttctttcct ctttataatt gtttagctta tttagccaaa
    18841 gcttcttttg cttggtcagc caatgcagta aatgctgctg catcgttaac agccaagtca
    18901 gctaacattt tacggttgat gtcgatttca gcaactttca aaccgtgcat taattttgag
    18961 tagctcaagc cattcatacg agctgctgcg ttgatacgag caatccacaa tttacggaag
    19021 tcgcgtttct tttgacgacg atcgcgatat gcgtagttgt atgaattcat tacttgttct
    19081 tttgctgttt taaataaagt gtgttttgaa ccgtagtaac cttttgctaa ttttagcact
    19141 cttttacgac gtttacgagt tactgttcca cctttaacac gtgccatgta taattcctcc
    19201 taataaaaat aaatcttcag attctgttat ttgtacttct tatttcattt ttgctagttg
    19261 ttggcgaata cgtttgaagt cgccactaga aaccatgctt gctttacgca attgacggcg
    19321 ttgttttttt gttttgccgt ggaaacggtg acttgtaaac gcgcggaagc gtttcaatcc
    19381 gcctttacca gtacgtttga aacgttttgc tgatccgcgg tgtgtttttt gttttggcat
    19441 gactatattt cctcctcaaa atctttcgtt atccgactat cggctgtcca acagccagtt
    19501 agtcattcaa attacttact gtcgtttttc ggtgccagcg tcaagaacat gctgcgtccg
    19561 tccattttcg ctttttgttc cactgttgca atatccgcag tttcttcagc taagcgattc
    19621 aagacttttt gaccaatttc tttatgggta atggcacggc ctttgaaacg gatagaagct
    19681 ttcactttat cgcccttttc caagaactta cgtgcattac gaagttttgt attgaagtca
    19741 ttcaagtcga tcgtaggact taagcgaact tcttttacat tgatcacttt ttgtttttta
    19801 cgcgcttcgc ggtctttctt ttgttgttcg aaacggtatt taccgtagtc catgattcgc
    19861 gcaactggtg gtttcgcacc aggggcaact aacacaagat ccaagtttgc ttgttctgca
    19921 atattcaatg cttctgcttt tgtcttaact cctaattgct caccatctga accgatcaat
    19981 cgtaactctc gtgcacgaat gccgtcgtta accatcatat cctttgctat ggtcattcac
    20041 ctccaaatat tatgagagaa agaaaagctt accgaataaa cggcaataaa aaaacgagtt
    20101 ctcttacaga acccgcgcgt acttcaccta atagaaccag tgaaaactat ctagcccagt
    20161 gacattatca actaaggcga gaagcgggtg cttctgcttt tatttctcaa ccatcatagt
    20221 atagcaaaaa ctaatctttt tgtcaatgtt tttcatacag tttgtcttcc ttttctgaaa
    20281 atgattagat tagcagactt tcttgcagtg attcccgctt ctttgctata ctaaagaaaa
    20341 acgaggtgaa cccacatgaa aaaaatcgaa cctattccac cttctcttcc tcttcttaca
    20401 aagggagagt tttatttaga agatgaggag atcttctctg gtcttctgat caacgggggt
    20461 gaccaaagct atctcgatgc caaaaatatg gtattaagag agagtcatat ccaaaaactt
    20521 acgatgcaaa aaacagtttt acgtcatttt gaatgcagta atgtcatttt tgaaaaatgt
    20581 gatttttcca atctggagtg gattggtggc agtttccacc aagtcgtgtt tcatcaatgt
    20641 aaattaacag gtacgaattt tgccgaaagt tatcttcgag actgtacttt cactgattgt
    20701 attgcttcga tggcttcctt tagtagtaca aacttgaaag ctgtctcctt cgatcattgt
    20761 caattagaag acagcgaatt ttatgaggtc acttggaaaa accttttttt gtctgacaat
    20821 cagttgaccg gttcgaactg gtttcgaact tctctgaagg gattagactt tacgactaat
    20881 ttcttcacag caatcgcttt atctcaagat tctttggcgg gactaatcgt caaccaagag
    20941 caagcacttg tgatcgccca agcccttggt ttgcagatca aagactagat caacgaatcc
    21001 gccgccacag tgcaataagc atccaaatag ataagaccaa actgatgatc aaggcgattc
    21061 cccatccgaa aacggaatgg gtaaagggta actggagatt cattccgaag aatcctgtca
    21121 caatagttgg aacggtcaag atcagcgacc agaccgtcaa aaatttcatc gtgtcattca
    21181 agttgttatt cagcaaatta ttataagtgc cagagagctg gtctaaaatc tgcgaagcta
    21241 agttcgtcat ttcaactgct tgtcgtgctt cgatcagcgc atcgtccaac tcttcttttt
    21301 ccttttctga caacttgcga taaatagcca atgccttgat ttgttctaaa agtactacat
    21361 tttgttttgt tcctgtaact aagtaaacca aaccgatctc taaatctgaa agttgcagca
    21421 gattcttgtt cgttgttttt tctcttaatt tcagattaag ccgctgacgt tcactattca
    21481 cttcctcgat taaaggaaaa aaggaatcag aaatcaaaaa caatgtacga aacaataaac
    21541 tgtatacact catgtctggc attcgttcca aaagcgatcg aattagtcga atcacgtact
    21601 cggtattcgg cgtggtaaat gtaaacaaac cgtcttcttt taaaataaaa gcgataggac
    21661 tagtttcata atgattatcg actttttgct ggtgcggaac atttgataca agcagtaacg
    21721 cttcatcaaa agaatcgtac tctacgcgcg cccgttcatt tttatctaga gaataagtca
    21781 gcatctcgtc actaatgcca tattcttctt ttaagttttt aacagctagc acatcgtttt
    21841 gctgtacatt gatccaaaaa ttacggtctt gattaaaata gtgtttttcc cgcatactct
    21901 atcctcctga catttgtttc cagtataaag aaaaaagtcg ctcaaataaa ggtttaccct
    21961 ttatttgagc aactgtaaat caaatggcta ctttggtttg gcgaatctct gctaattttt
    22021 cttcgatcat tttcaagact tcttcttttg cttgaggatc ttccacaaaa ttatagcggt
    22081 ctccatcgat ttggattttt ggactttctt tgtattcttc ataccattga tcgtaacgtc
    22141 tgttcaattc tttgtaataa tcgtatagac ttggatcaaa ggacaattgt tcatacgaac
    22201 gaccacgttt ttcgatacgc tccaacatcg tatcaaaaga tacacgaata tgaactaata
    22261 aatccggatg ttttttatgg gcagcatagg gaagttcttc catcatgttt tccagcagtt
    22321 catcatacac acgaacttct gtttctgttg ctcttcctag atctgcattt agatggaaaa
    22381 gcagtgaatc ttcataaatc gaacggtcca atacattatt gtcatctttc attgcttgtt
    22441 tgatgcttgc aaaacgttta ttcaaaaaat aaatttgcag caaaaaagca tactgttcag
    22501 ggtttgcata aaataagggc aagacttcat tatcatcaat cgattcataa aatgcctgac
    22561 tatcaaagtg ttcagccatc atttctgtta aacttgattt tccggcacca attgtacctg
    22621 ctaaaacgat cacgctcatt tacctccagc tcacttcatc actaaatatt gtgtttaact
    22681 ccaacctttt taaatatacc cccaatatct agtagtgtca attgtatttt tttctagtca
    22741 aagaagaaaa aaagtcaaaa aattcttaag aaaaaagtgt tttttcttta gaaaacgtat
    22801 tcttagtttt acttctgaga tggttttagt aaaataaagg aggaatgttt tttgagaccc
    22861 ttagtggaca aaaaaattcg tgaagcagcg caactcgttt tgggcgcttt attttttgct
    22921 taaaaatcac ttttacgtga gaaggagtta gattatggca aactatggcc aaggagaatc
    22981 aagcggaaag atcatattga tgggcgagca cgcggttgtt tatggagaac cagcgattgc
    23041 ctttcctttc tatgcaacaa aagtcaccgc attccttgaa gagctggatg caatggacga
    23101 tcaactggtt tcttcctact attcaggaaa tttagccgaa gctcctcatg cattaaaaaa
    23161 tatcaaaaaa ttattcattc acttaaaaaa acagcatgac atccaaaaaa acttgcaact
    23221 gaccattgaa agcacgattc ctgctgaacg tggaatggga tcaagcgctg cagtcgccac
    23281 agcagtcact cgtgcttttt atgattactt agcatttcct ttgtctcgtg aaatactatt
    23341 agaaaatgtc cagctttcgg aaaaaatcgc ccatggtaat cctagtggaa tcgatgcagc
    23401 cgctactagc agcttgcagc cgatttattt tacaaaaggg catcctttcg actacttttc
    23461 tttgaacatc gatgcttttt tgattgtcgc tgatacagga atcaaaggac aaacaagaga
    23521 agccgtcaaa gatgtcgctc acctctttga aacccagcct catgaaactg gacaaatgat
    23581 ccaaaaatta ggatacttga cgaagcaagc aaaacaagca atcattgaaa attcaccaga
    23641 aacgttggca cagacaatgg atgaatcaca atcacttctg gaaaagctga caatcagcaa
    23701 tgattttctt aatctattga tccaaacagc aaaagatacc ggggcattgg gtgccaaatt
    23761 aactggcggt ggacgcggtg gctgtatgat tgcattagca caaacaaaaa caaaagccca
    23821 agaaatcagt caagcacttg aagatgcggg tgctgctgaa acttggatac aaggattagg
    23881 agtacatacc tatgtttaaa ggcaaagcac gcgcatatac caacattgct ctaatcaaat
    23941 attggggtaa gaaaaatgaa gaactcatcc ttccaatgaa caacagcctt tcgttaacat
    24001 tggatgcatt ttatacagag acagaagtca tcttttctga tagctatatg gtagatgaat
    24061 tttatctaga tggcaccttg caagacgaaa aagcaacaaa aaaagtcagt cagtttcttg
    24121 acctttttcg taaagaagcc ggcctctcac taaaagcttc agtaatcagt cagaatttcg
    24181 ttcctaccgc agctggatta gcctcctctg ccagcgggct agctgcttta gcaggcgctt
    24241 gcaatactgc tcttaagctt ggattagatg atctctctct ttcaagattt gctcgacgcg
    24301 ggtctggttc agcttgccga agtattttcg gtggtttcgt cgaatgggaa aaaggccatg
    24361 acgacttaag ttcttacgct aagccagtcc cttccgattc tttcgaagac gatttagcaa
    24421 tggttttcgt tttgatcaac gaccagaaaa aagaagtgtc cagcagaaat gggatgcgtc
    24481 ggacagtcga aacatccagt ttttatcaag gctggttaga ttccgttgaa ggggatctat
    24541 atcaattgaa acaagcaatc aaaacaaaag atttccaact tctcggagaa acgatggaaa
    24601 gaaacggact aaaaatgcat ggaacgactt tagctgccca gcctccattc acttactggt
    24661 ctcctgacag cttaaaagcg atggatgcgg tgcgacaatt gagaaagcaa ggcattccat
    24721 gctactttac gatggatgct ggccctaatg tcaaagtttt agtggaaaac agccatttat
    24781 ctgaggtaca agaaacattt accaaattat ttagcaaaga acaagtaatt actgcacatg
    24841 ctggtccagg aattgcgatt attgaataaa gggagatttt tatgattgaa gtatctgcac
    24901 caggcaaact ctatattgcc ggagaatatg cagttgttga aacaggccat ccagcagtta
    24961 tcgctgcagt cgatcaattc gtgacagtca ctgtagaatc tgcacgaaaa gtcggaagta
    25021 tccaatctgc acaatatagt gggatgcctg tacgttggac aagacgcaac ggagaattag
    25081 ttttagatat tcgggaaaat ccttttcatt atatccttgc tgctattcgc ttgactgaaa
    25141 agtatgcaca agaaaaaaac attcttttat ccttttatga tctgaaagta acaagtgagt
    25201 tagacagttc aaatggccgg aaatatggat tgggttctag cggtgccgtg accgttgcaa
    25261 cggtcaaagc cttgaatgtt ttttacgcgt tgaatttatc tcagttggag attttcaaga
    25321 ttgcagcact agccaattta gcagttcaag ataatggttc ctgcggcgac atcgctgcta
    25381 gctgttatgg tggctggatc gctttctcaa ccttcgacca tccttggctc caagaacaag
    25441 aaactcagca ttctatcagt gagttacttg ccctggattg gccaggtcta tccattgagc
    25501 cattgattgc tcctgaagat ttacgtttat tgattggttg gacgggtagc cctgcctcta
    25561 cttctgattt ggtcgatcaa gttcaccgtt cgagagaaga taaaatggtg gcttatcagc
    25621 ttttcttaaa aaatagtaca gaatgtgtca acgaaatgat caaagggttt aaagaaaata
    25681 atgtaacgtt gatccaacag atgattcgaa aaaaccgaca attactgcat gatttatctg
    25741 caatcactgg ggtcgtcatc gaaacgcctg ctttgaacaa attgtgtaat ttagctgaac
    25801 agtatgaagg agccgcaaaa tcttctggtg caggtggggg cgattgcgga atcgtaattg
    25861 ttgaccagaa atctggcatt cttcctttaa tgagtgcatg ggaaaaagca gaaatcactc
    25921 cactgccgtt acatgtctat agcgatcaaa gaaaggaaaa ccgatgaatc gaaaagacga
    25981 acatgtttca ctagctaaag cctttcatga taaacaaaaa aacgaatttg acttcgtacg
    26041 gatcatccat aaccctttgc cgcaaatagc agtttctgat gtcgatctaa gtacacaggc
    26101 agttgggttt acactaagca gcccatttta tatcaatgcg atgactggcg gaagcgaaaa
    26161 aacaaaaaaa atcaaccaag atcttgcaat cgtcgcaaga gaagcagatt tgatgattgc
    26221 cactggttca gtcagcgctg ccttgaaagt cccttcttta gccgatactt atacgattat
    26281 gcgacaagaa tatcctcacg ggaaaatcat tgccaacatc ggtgcaggga cttctgtcga
    26341 aagagccaaa gaagctatcc gattgtttca cgcagatgcc ttacagattc atttgaatgc
    26401 acctcaagag ttggttatgc ctgagggaga ccgtgatttt accaattgga aagtacttat
    26461 tcaagaaact caaacagcca ttgacgtccc cctcatcgta aaagaagtcg gttttggcat
    26521 gacaagagaa acgctcaatg atctagctgc tttaggagtt catacagttg atatcagcgg
    26581 tcgaagcgga acaagcttca cccagatcga aaacgcccgt cgctccaagc gggaactgag
    26641 ttatttagct gactgggggc aatcgacagt ctcttcattg cttgaagcaa atgaagcaga
    26701 cacttctatg gaaatcctag cctccggagg tatccgcaat gcctatgaca tatttaaagc
    26761 cctttgtctc ggcgcaaatg ccgtgggtac ttcaggaacc gtactgacgc atctgatgaa
    26821 tcacggcgta gaagaaacta ttatactgat gaagcaatgg caagaagagc ttcgtctgct
    26881 ttatactatg gtcggcgcaa cgaataccgc ggccctacac caacaatctc tgatcttttc
    26941 cggaccagtg aaggattggt gcgaagcaag agggatcgac ttagtgaagt atggaagacg
    27001 cacagaaaag agcgtgggac aaaagtaaag aacacttttg tctcacgctc taaacacgta
    27061 caaacggcgg aagtaaaagc aactccttcg gaaataagct gaaattcaca aaaatttgaa
    27121 aagcaatttt cgtgaattcc ttcttatttc ttggagttaa atgcttctgt cccagcctct
    27181 tttttcgaat aaatgatgtt taatcagctg tccttcggta ttcgttcaat ccgctgattt
    27241 cacaacctct ccactaaaca gtgtactaaa gctcttttaa ggttgttttc cgatataggc
    27301 aagtatgcct ccgtccacat acaagacatg gccgttaacg aaatcagatg cgctagaagc
    27361 caagaagaca gatggtccag ccaaatcgat tggctcgccc cagcgtgctg ctggcgtacg
    27421 tccaacgata aattgatcga atggatgacg ttcaccgttt tcttgtgttt cgcgtaatgg
    27481 agcagtttgc ggtgtagcaa tataacctgg tccaattcca ttacattgga tattgtattg
    27541 accgtattca gaagcgatgt ttttcgtcag catttttaat ccgccttttg ccgcagcata
    27601 agcactgacc gtttcgcgtc ctaattcact catcatggag cagatattga tgattttacc
    27661 gccgcctttt tcgatcatat ccggaataac tgcttttgaa acgatgaatg gggcatttaa
    27721 atccacgtcg attacttggc ggaagtctgc cgcatccatt tcgatcatcg gtgtccgttt
    27781 gatgatccct gcattgttga ctagaatatc aactgaacct acatcttctt tgatctgttg
    27841 aaccatcgct tgaaccgctt cttcatcggt cacatcgcag acataacctt ttgcatcgat
    27901 gcctgcttct ttataatgcg ctataccttc atcaactgat tcttgattca agttattaaa
    27961 tacgattttt gctcctgctg tagctaaaga gcgtgcaatc tcaaatccaa taccatagac
    28021 agcaccggtg actaatgcta cttttccatc taaacgaaac atatccatac taaattccat
    28081 cattttctct cccttatgct tattttaatt gatccatttg caccatatcc atgtctgtat
    28141 aggtgatatt ttctccgcac attgcccaga tgaatgagta attgcttgta cctacacctg
    28201 aatggatcga ccagcttggc gaaataatgg cttgttcatt gtctacaact aaatgttttg
    28261 tttcatctgg tttgcccatc atgtggaaca cacgtgtatc ttcattggca taatcaaagt
    28321 agacataagc ttccatacga cgttcatgtg tatgacaagg catcgtattc caagcgcttc
    28381 ctggttctaa aatcgtataa cccatttgta attgacagct ttcgcataca tttggatgga
    28441 tgtattggta gattttacgt tcattcagtg tcaggccttc accagtctcc attggtttta
    28501 cttggtcgat actgattttt acatttggat atttatgatg agctggaaca gaactaatat
    28561 agaatttagc tgggttttca gcatcttgag aagaaaatac aacatgtcgt gtttcttttc
    28621 cgatatagta tccgtcttgt tttttcattt cttctttttg cccatcgatc tcgatgaatc
    28681 ctggtccacc gatattgatc acacctagtt cacgacgctc taagaagtaa tcaacaccta
    28741 gttctttgtc taatgtgatt tctaattctt tttcagtagg tgtcactcca ccaaagatca
    28801 ttcgatcgtt gtgcgtataa gtcaaactga ttttccctgg ttcaaatacc ttttctacta
    28861 aaaattcttt tctcaattgt tccgttgaat aatgacggat atcttctgga ctgtgtgtat
    28921 aacgtgtttc catttcttgc attttcttct actccttcta tcgaatgatt tttccagagc
    28981 cgcatgctaa aaattgtgcg acttcttctt gactaaattg gttgcagtcc ccatggatcg
    29041 tatgcttcaa ggcagaagct gccgtagcaa aatcaatgat ttcttgcgga gacatattgg
    29101 ataaaatccc atggagcacg ccacctgcaa aagcatctcc gccacctact cgatccacga
    29161 ttggggtgat tctatggact tgggattcca catattcatg gttcatccac aatgtcccct
    29221 tcaattcatt ttcacttgct gaatgaacgg tacgcttggt cgaataaaac acctgaatat
    29281 tcgggaactt ttcctgcatt ttttgataat aataaattag aggttgttct tctgcttctg
    29341 gcgctttctc gatacctaac aaataaagag catccatttt tccagctgag cagatatcta
    29401 ctaaaggtaa aagctgatgg attacttcgc tggcttcttg ctgtgtccat aattttccac
    29461 gatagttgat atcgaagctg atcaggcagc cagctttttt tgcagcttct atcacctgtt
    29521 tcgtcatttt ttgccatttt ttagacaaag ctggggtgat tcctgaaaca tgaaatatat
    29581 ctattccttg gaataactcc tctagcgacc attccaaatg atccatttca gcaaaacttg
    29641 atccggcacg atcatagatc actgaggcgg cgcgttcgcc actaccagtt tccatataat
    29701 aagtacctag tcttgatcca ccagataata cctgtttcgt atctactcca taacattgca
    29761 agtgcttttt gactgctttt cccaatgcgt tatcaggtac ttttgtagca aaaatcgctt
    29821 catgtccgta attagctaaa gaaattgcta cgtttgcttc ccctccgcca taatgggcag
    29881 cgaatcgttc acttgaatcg atacgggttc cctgctctgt ggacaatcgc aacatgattt
    29941 ctccgagtgt cactactttt cccataagca gctacctctt gatttctttc atttttgctg
    30001 catactgttg cgcgacttcc gttactttgt caaaatctcc tgtagctgcg ggtgctaaaa
    30061 ggttcccacc tactccgact gttacgacac cagcatcgaa ccactctttc atattgtcca
    30121 gactcacacc gccagttggc atgatattga cttgaggcat cggcgccttg aaggcagaaa
    30181 tgatacttgg tccataagcg cttccaggaa atagtttgac gatatctacc ccgcttttca
    30241 gcgctgtttt gatctcggta atagtcatac atcctggtaa gtaaggaatt tgatacagat
    30301 tgcacatctc tgccgtttct tgatcaaagg aagggctaac aatatactct gcgccagcta
    30361 agatagccaa gcgagctgtg acagcgtcta atactgtgcc tgcgccaatc actatttctg
    30421 gttggtcttt gtagaatgac aaaagttctt tgattacttg atctgcttga gggactgtaa
    30481 aagtcaactc aataccagtt agaccacctt tgatgattgc gtggcaagca ttcaaagctt
    30541 cttctttgct ttttccgcgt accaccgcaa tcactccggc gtttttcaat cgagataaaa
    30601 tatcaatttt tttcatcttc tccacctatt tcctatttag aaattttatt ttataacttg
    30661 gaaatctata cccatattat acggcagaaa agaaaaattg caaacgcttt tttcattatt
    30721 tttgaattct ttgctcgatt tcgctttttg tttgcttgag ggcactgatt atttgttctt
    30781 ttgtctcatc tgttaaacga tatttcggca tacttacact aaatgcacca atgatttgtt
    30841 cgtttttcac gattgaggct cctatacaaa aaatatcacg ttcgatttct tcatcgtcaa
    30901 atgcgatgtg ggtttctttt accgttttga tttccttttt caaccgtaat gcattggtga
    30961 tcgtatattc tgtgtaaggg atcaacggat gcttttcaag ataatcagtg tactgctctt
    31021 cactgaattc tgctaatacg gctttgccca tcgcagaatt gtataatggt cgggtgattc
    31081 cgatttttga agacatgcgg atcgtttgat gttttggatc tagtttgttc acgtacaaga
    31141 tctcattgtt gtccaatacc cctaagtgga tagtctcatc gatcttttgc tgcagctgtt
    31201 ctaaaaacgg taaagtcaac tctaccaaat cgatttgttc aatgttttta ttcgcgtagc
    31261 gaataagctt tgcacctaaa cgatagtttt tctctgaatt tttatttacg tagccgatca
    31321 tcaacaaagt atctagtatt ttcaagactg tagaagaggt cattcccaca ccctttgcga
    31381 tcgtctgcaa agagacatct tggttttccg ctaaatagtc tagtatttta gaggctttga
    31441 tcaatacagt tccataaggc tttttatttt ccatataata ttctcctatt tctttataag
    31501 aaaaattata gcggaaatac catcaattta aaagagatat ccagatataa actaccattt
    31561 ctctttacag gcaatttaat gttgaagatc cgcttcgttt ttacatcaaa ctttgatata
    31621 aagcaatgat ttcttctact gtcgtttctc ttggatttcc tggtgtgcat acatctcgca
    31681 aagcatcttc tgcaattgct ggaatatctg cttcttttac acctaattca gaaatggttt
    31741 ctgggattcc aaccgctttg ctcaaccgat cgatctcacc acaagccgct tctcttacat
    31801 cttctaaaga catttcagct gctcctttaa tccctagaac aagagcgatc tcacggtact
    31861 tttctccagt atattctttg ttatatttca tgacagttgg caaaagtgct gcacacgcta
    31921 cgccatgagg aatgttgtac catgcactta acgggtgagc catcccgtgt accagtccta
    31981 aaccgacatt tgagaagccc attcccgcaa tatactgtcc taatgccatt ttttctcgcc
    32041 cattttgatc gccatctaca gaagcttcca aagaatggcc gatgatttcg attgctttta
    32101 aatgcagcat atcagtcatt tcccaagcgc cttttgtgat aaacccttca atagcatgcg
    32161 tcatagcatc catacctgtt gatgcagcca attttttcgg cattcccatc atcatatcgc
    32221 tgtcgatgaa cgcgacgatt gggatatcat gaggatcaac acaaacaaat tttcggtgat
    32281 ttacttcatc tgtgatgacg tagttgatcg ttacttctgc tgctgttcca gaagtcgttg
    32341 gtatagctaa tataggtaaa catggatttt tcgtatcagc aacaccttct aaactaatga
    32401 cgtctgaaaa ctctggattc gtcaaaataa tcccaatggc ttttgccgta tcgattggcg
    32461 aacctccacc gattgcgatc aaacagtctg cctctgcctc tttaacaaaa gccactccat
    32521 cttttacatt ttggatcgtt ggattaggta cgatcccgtc gtataaagca taagcgattg
    32581 ctgctttatc tagaagttct gttacttttg ttgctatacc gtgctcgatc aatcctttgt
    32641 cagtaatgac agctgctttg ccgaatcctc gctgctgaaa ttcagggacg atcgactcaa
    32701 tcgctccttt tccaaaatac gatgtttcat ttaaaatcat tcgattactc attttctatt
    32761 cctcctaatt tgtattattt ttcacaataa aaacgaaaga accccaagca accggttgcc
    32821 cagttgcttg ttgctacagt tcaaagactg gcatcaattc ccaactgact ggagaggcat
    32881 ctggatttgt ctccatgata tcttccatgt acttccacca tttttgattg atagatgtat
    32941 ttgccatttt ttcccataac ttttcatctt cgatcactaa gtaaccaaat aacaaacttg
    33001 tactcggatc aagatagatc gaatagtcga tgaccccgtg ttcacgaagt gctgtacgca
    33061 tttctggcca aagttcatca tgtctttttt tgtattcttc ttgtttttct gggtaaactt
    33121 tcatgcaaaa agcttttttc accatgtcag acacctgctt tcgtatgaac ttcctccaaa
    33181 taacctgctt ttggagtgac accaaacgca tctgctaaat gccacaggtt ttcgtccgtg
    33241 attgtttgca agattggtcc ttgcgctttg acgtacgtat agacttctgc tgccttttct
    33301 gctgtctcga tcaaaccaaa gacttcatcc atgtcttttc ctgacccgta gattccatgt
    33361 tgtggccata aaaccaatcg agtttctttc attttttcag ctgttgcttc cccaatctca
    33421 tttgttcccg gaaccatcca cggaatgatg gaaattcctt ctggaaaaac aactaagcat
    33481 tccgtacaca tttgccatag cgtacgacta aaggaacgtt cgtctaattc atgcgtaaaa
    33541 ctcatcgcta atagatgact agcatggcaa tgcataacga tccgattatc tgggtctact
    33601 tctaaacggg cgatatgact catgaaatga cttggcaact cgcttgtagg aaggcattcg
    33661 ttttccagcc cccacaaaag ttccagtgtt ttgccatctt cagcaactcg aacgattcca
    33721 agattctcgg caggttcgct cgctacattt ttaaaatatc ttcctgaacc agttacaata
    33781 aaatagcatc ctgctaaacg gctggcatca aaaatcatcg agatgcggcg gatcactttt
    33841 tcaggatcca agaacggtgt gatctcttct tcttttagta aataagaaat attcccgcca
    33901 tttctttcat cccatcccaa gcgataaaga ttcgacgtcg tttcgatcat ttctttcaca
    33961 taaggcgctt gtaaaatatc tatttttttc aatatagcca cactcctatt ttcttaattc
    34021 caacacgtct ttttgatatt cctggacttc ttccagccaa tccaaaccaa ctggaacttg
    34081 atttttgtaa cagaaataat tccatacatc ggcatacggg aaatctttca attcttccgt
    34141 ataagccatt cttgaagtaa agtcaaaagc cagctccatt tctttcaatc gctcaactgg
    34201 ttccagcata gctttcagca gtgctttttg tgtatttctc gtaccgatga cccaagcagc
    34261 gatacggttg atcgttgcat caaagaaatc cagaccgata tttgtttttt ccaacaattc
    34321 gttacggact aattctttag cgatttcctg caattcatca tccatcaaaa ccacatggtc
    34381 tgaatcccaa cgcactggac gggaaacatg caacatgatt cctttgctga ataaagctaa
    34441 tgaagataat ttattggaaa tcacttctgt tggatgaaaa tgtccagcat ctagacaaac
    34501 aagtttgtca cgagtcaacc cgtaacccat ataaaattca tgggaaccga ctgtataagc
    34561 ttcagcgcct aaaccaaata gtttgctttc tactgcatct tgtacatacc gttcatctaa
    34621 ctcttctgta aaaatttcat cgagtgattc cattaaacgt tcccgtgggg taaaacgatc
    34681 aatcggatta tctttcatcc catcaggtac ccaaaagtta ttgatacttg tttgcccagt
    34741 ttctttccca aagtactccg cgattttgcg gcttcttttc ccgtgttcga tccagtattc
    34801 acgaacttct ttatctggat gagccaatgt aaagccgtct ttcatcattg gatgcgaaaa
    34861 gaaagtcgga ttgaagtcaa gaccgatttc ttcttttttt gcccactcta cccatttttc
    34921 aaaatgtttc ggctcaattt catttagatc gacagattct tctgtatcca aatagatagc
    34981 atgaaggttc aatttgtgtt tgcccggtat caacgaataa gccttctcca gatcttgtct
    35041 aagctcttca ggtgttcgtg cggctcctgg aaaattccct gtcgccatga ttccaccggt
    35101 caattcgcca tccggtgtca agaaaccttt gacatcatct ccttgccagc aatgcataga
    35161 aattttgatg tcctgtatct tttctagtac agcatctgta tctacaccga tagttgcata
    35221 tttttctttt gcttgttcgt aatttctttc aatcgtgttc atacgattac tcctttgatt
    35281 ttattcacgt accattccat cgtgttttgc ttattttcat ctgggtaaaa agtttcacat
    35341 ggaaacgact gtttgattac atttcttgct tgttctatat tcgaaaactg acctgtactg
    35401 agcatttgca tggcaacatt cccgattgct gtggcttcac taggtcctgc ttctacaatg
    35461 attccggcat aatctgctgt caattgattc agtagacgat tattcgatcc gccccctacg
    35521 atgtgcagct tttccaattt cgttccagtt aagtgttcta ctttgatcag ctcttgtgcg
    35581 taacaaagag caagattatc atacacacaa cgagcgatag ctcccgatga gacagggact
    35641 ggctgctctg tttcaaaaca gtattgctga atctcttcta tcatatttgg gggattcaaa
    35701 aatcgagggt cattgatttc catcacttgc tgcagcggtt tttcttttgc agcaagctct
    35761 gccaattccg cataactgta ctcgtactct tgcattcggg caacttcctg gatcaaccac
    35821 atccccatga tgtttttcaa aaaacgcacc gtgttatggg caccccattc attcgtataa
    35881 ttttcagaaa aagcattgcg agaaacattg gcgatctttg tttcaatccc taaaagcgac
    35941 catgtcccac tgctgatata accccaacgt tctccttgac ctggcgttcc taatacagct
    36001 gacgccgtat catgacttgc tactgtgata aaggtcacat ctggcaaatc atattttgaa
    36061 aattgttctt tttgcagatc tcctagtatc gttcccggct ctgtcaatgg tggaaataat
    36121 tccttcgaga caccgatttt ttcaagaagt tctatttccc attcttttgt ccctgcattc
    36181 agcagctgca tagtagatgc attagttttc tccgtcacca tgttaccagt aaagacatac
    36241 cctaaataat caggtatcag taacaattta tgtgcttttg ccaaattttc tttttcttca
    36301 gcaaacaatt ggaacaaggt attgaaaggc tggatctgaa tccctgtctg ctcatacaac
    36361 ttatctagag aatagatttc agaaaactgt tctactgctc cattggtacg cttgtcccga
    36421 taagcaatcg gatcatttat ccgatcccct tgttcatcaa tcagacagta atcgactgcc
    36481 catgtatcga tccccgcaaa aaggcgatca atccctgtct gctttaattt ttcaaatcca
    36541 atcaaaatct ctttgataag ataatcgatc ttccagcgat cgtgaccgtc tttgttccga
    36601 aagccgtttt tgaaccggtg tacttcttcc aagatcaaag aaccttttgc atccctcgta
    36661 cttttcatta gtcgtccgct tgatgcaccg atatcgatgg caacaaatgt tggattcatt
    36721 tctccacctc ttttacttta ttgttgatta gcactttatt aataaagcgt tatcatttat
    36781 tgacaatgct atcataatac agaatcttat attttgcttc acactatttt ggtatataat
    36841 tgcattatct tgacaagttg ggagtgttta catggattac tgggaaaaag ccaaccactc
    36901 atggtcggaa gactcaaaaa gagtgatctt gacgcctaca caaagaagca ggaatttatt
    36961 tttttatatc caagaaatcg gttacttcaa agcaccaatc ccttactata ctgaacgagc
    37021 acatttacct tcttacttga taaagtttac tttgtctggc aaaggttcgc ttacatataa
    37081 tgataatcag caacagctaa aagctggaga cttatttttt attgactgcc aagaatatca
    37141 gcgttatcaa acgatcagcg aagaaccatg ggaaatggat tggatccatt tgaatggtca
    37201 gaacgtccaa tcattttatc aggagttcac aaaagacggc cataacacct tccattcaac
    37261 aggagatcca tcagaaaaca agatccacca tttgatcaca gaattgatcc acatgcaaca
    37321 aggcacgaat gcccgtaccg atttccagtc ctctgtagct atccacgagt tgctgaatga
    37381 actgattttg caaaagtatc agctagattt cgaagaagag gatattcccg cctacgttta
    37441 caaactgaag caatacttag acgaacattt caaagaaacg attacacttg atcaattaga
    37501 acaacaattc ttattgaata aatatcagct gagcaaagat ttttccaaat ttatcggttc
    37561 tccaccaatc gattatttga tcagcaaaaa actttcttac gctaaagacc ttcttcggta
    37621 tacagaattt acggttcgaa tgatttccga agaaataggg attgagaatt ttgcttactt
    37681 tagccgcctg ttcaaagcaa aaacaggact atcgccgaga gactttcgta aattcagctg
    37741 attcatataa tatgtacgtc attttttcaa aatattttga aatatataga taaaaataaa
    37801 ataaccgcag tttctgcttc tatgtaaaca acagcagcta ctgcggttat tttttagtga
    37861 tcattctcat tgttcatctt caaaatgttc ataatgaacc aactgtttct gtgtatcacg
    37921 tttcaaaaat tctttaggcg ttatgccgaa ctctctcttg aatgctttca gaaaatgcgg
    37981 ataagaagaa aaaccacttt tactatatac agcactagag ctgcggtatt ctcgcaacaa
    38041 gtgcttggca tagatcagct ttttcttcat tacatactga tgaaacgtaa atccagtgta
    38101 ctttttaaat tctcgtgtga tatggtattt gctgacaaaa aactgctttt ccatttcctc
    38161 taaagaaagc ggatgagata aattttttga gatatattgt aacatttgtt ccacacgctc
    38221 attaggaact acagcattct gttcttgcgc actctcttct ttttgtacaa cttgattgag
    38281 aaaaatcaag tattctacca gagcttgttc atattttatg tcttcaccgt aaattttttt
    38341 atcaggagga tggtcgataa atgataattt ttgcttcaat acttcctgtt ctatttgcaa
    38401 tacacgactc ctcttctctc ccattggttg aaaacaagcc gatagattag accatggcgt
    38461 ggaacgactt tctagaaaag aaggggtgac aaagatatag acacgctcga atacatctga
    38521 agattggcgg acgatacgat gcaaatcatt ggaatggatg agcagcacac ttcctgcttt
    38581 gatcgtaaat tgtcgtccgt tcaaataaaa agtcgcttct ccctttaatg tagcatggat
    38641 ctcatagaaa tcatgatgat gatagatcgt tttattttgg ctgacgacat ctttgacatg
    38701 atagatttca tactgatcag aaaccatcgt attgacttgt tcaccgctga ttttcttttg
    38761 gagcatgtgc cgcacctcct tttgttcact tatgcacaat tttattatac cacgtttttt
    38821 gtaatcaaaa agagctgctt ttatatactc ttataaaaaa gaagagacgt ggcatcttct
    38881 agccccgccc cctccattct aaatattagt taaccaacgt cttctttaca ttattcaaga
    38941 agacttcttc cataacgaat cccatcatct tttgtttctt caagaaccac atacaggtac
    39001 ggacgattct tcatgatgat ttctttgatt tttgtgtact cgatcacacc gtctcccaaa
    39061 tttaccggca cgattttttc ctgttcgaca cgaaaatctt tcaaatgaac cgcacatatc
    39121 ttttcaccaa aacgttcaaa agcttcttct accaattgga cttgttcttg ataatcacta
    39181 cttgtgatca aattggtcgg atctaaaatg attcctagat agtccgaatc tactgcttgg
    39241 atcagctgct ctacccttgc taaagaatac accggatgat tcaaacctgg ttctatcccc
    39301 accatcattt ggtatttttc tccagctttt accaagcgac ggataacgga cacagcttca
    39361 gcaaatgctt catctgtgaa attttcttcc gtatattgga tttccggcaa aacacatcca
    39421 gtttccgaag caaccatcga cgcaccaaag gaagaagcat agcgaagata ctgctcgaac
    39481 tttgtcagca actcttgtcg tatcgttaaa tctggatgaa tcatattgat atagcaactt
    39541 aaaattccta cggtcacttc ttgcttttct aaaactcgtt tgacataatt tcccatccca
    39601 gaattgatct catttgcgcc agaaggtatt tcaggaaacg aaagacctaa ggcgagctgc
    39661 agtgtatgaa tcccttgttc ttttgttttt tctgcaagat cttctatcgt ttggacttcg
    39721 gaaagatcat gtcctctaat tgtaatgttc aacataacta ttctcctaac tcagcatatt
    39781 gggtagccac atgacgattt gcgggaagta agtaatcaaa aacaagacga ctaagataac
    39841 cccataaaaa ggaagaagcg gtttcagcat tgcctctgct tttacgcctc ctacacttgc
    39901 accgacatat agtcctgtac ctactggcgg cgtgatggag cctacacaca gattcatgat
    39961 tgaaaacaac ccgtaatgta caggatcaac ccctacactt gtgacgattg gtaaaaatat
    40021 tggtgtaaaa atcaagatag caggcgccac atccataaac atacccacca gtaataacac
    40081 aagattgact aataacagaa taataaattt attatccgtt acgcccataa tcaacgaact
    40141 aattgcctga ggaataccgg taaacgccat ggcgaaagac atcatggaag aagtagccaa
    40201 taagaacatg atcgtccctg acattgctac tgattgaaac aacatattag gtatatcttt
    40261 tagttttacc gttttatagt aaaacatagc aatcaacagg gagtaaatga cagctatcgc
    40321 tgaagcttct actgctgtaa atatccccgt caagatacca ccgataatga tgacaatcaa
    40381 tagaaggcta ggaatcgcct cttttattat ttttccagca tgagccatct gtcctttttc
    40441 gacaacaggg tatttattct ttttagcaac gatgaatgct actagcatga ttcctagcgc
    40501 ccacaaagcg cctacgagat aacctcccat aaacaaagca gagatcgaag caccaccagc
    40561 aacaagtgaa tacatgataa aagcagtact tggaggaatg accatacctg tcggagctga
    40621 cgcgatattg accgctgtcg caaacttccg gtcatatcct tcttccactt gctgagggat
    40681 caacactccg ccaatcgcgg tagaagcggc aatggccgag ctagagatgg aaccaaataa
    40741 agcattccct aacacattcg tatgagccaa agcccccggc acgcgcccga cgaacaacat
    40801 cgcaaaatcc actagtttct tagctatccc tccattattc atgataatgc ccgagagaac
    40861 gaaaaacgga atagcgatca gcgaaaaact attgatactt cccaccattt tttgagctga
    40921 actaaaagca gaaacatcaa acggtataac taacaataaa gtcatcatcg atgagaatgc
    40981 aatacttata gcaatcggca tccctaatac aagcaacaca acaaatacaa aaaataacac
    41041 taatccggct tctattgcca ttttattcct ccatttttat attttttctt gaattgctgg
    41101 cttgttgctt aatgtatcga ttagattgat caggctatag ataatgatga gtacccccga
    41161 tacaggtact gacagataaa catatcccat aggaatactt aaagaaggcg agatctgccc
    41221 cattgtcaat gtgacagcat tccatccgcc atacaccatg atcatcgcag caaataccag
    41281 aaataaactt tgaacaacaa cttctaaaat tttacttttt ttgccagtta atttttcact
    41341 taaaaccgtt acggctaaat gtgctttttg tcccacaaca tacgcggaag acaacatggc
    41401 aaaccagaca agaccgaatc gaacaagctc ttccgtgacc gtatttggat ttcctaaaac
    41461 cgttctggaa aatacttgcc ataaaacaac agcgaccatc ccaacaagca aaacagctcc
    41521 caggatctct aataccttgt ttaaaatcat tttcatcaca gctacgctcc ttgctcttgg
    41581 atcttttgat aaaggtcttt gtaggtagga tcgtttttga atatatcatg aagtggggca
    41641 actgcctctc gaaacggtgt attatctaca tcattgaatt ggactccatg ttcttcttgt
    41701 gctaaagctt tttcttcttc aattgctttt gcaaaagctt caatttcaaa aaccgttgat
    41761 tctttcgctg cttcttcaat ggctttttcc tgctcatcag ttagctgttc tttgatggca
    41821 tcattcatga tgatgatatc tggcacacgt gtatgctcat cataggaata gtatttagcc
    41881 acaccaccat gtccagctgt atacaagaca aattcattgt tttctgatcc gttgatcaaa
    41941 ttggattgaa gagacgtgta cacttcatca cttcccatag gtacgggcga accgcctaaa
    42001 agctctacca ttttgatagc ggtttcgctt tgcatcacac ggatcttctt tcccttcaaa
    42061 tcttccggcg tatggatcgg accgtctacc atataaaagc tgcgctgacc agaatcataa
    42121 taggtcaatc cggtaaatcc taaatttttg gtcgattggt agattggctc cattatttct
    42181 tcattatcca tcaccttaaa gaaatgttct tcatcattga atagataagg aactgaaaaa
    42241 atcgaataat ctttagagaa actttccaac gctgaggcac ttacttttgt gaaatctact
    42301 gctcctgact gtgtcaattc gatcagttca cgttctccac ccagttgtcc atctgggaaa
    42361 tactggatct gtacggaacc atctgttttt tcttttacta aacgcccaaa ttcattcatt
    42421 gcatcaatta ctggctggct gttgcttgca taagcaaagc gcaaggtaac tatctcattt
    42481 acatctgcat ctgcgacagt tgccacacta gaattatttc cgcagccgct tagacctagc
    42541 agacctaggc taagcgaact tgctgcaaac agcagtgatg tttttttcat atgggtttcc
    42601 tttcttttaa caataagaga cgagcaattc tgtcaaacaa agcaccgtta acgactgtcc
    42661 ataaggcatt gctgtgattc cgatattccg ataaaaatct aaactgtccc ccattcctgt
    42721 cccgattgaa acgttttgaa cttctccttt ttcatcgatt tgttcaagca atccttggat
    42781 agcacgataa gcgacttctt tatattcttg tggtaaataa cgtttatgga ccgctttcaa
    42841 aataccgtaa gcaaatcctg cagttgcaga agattctacg taagaagaag gatcatccaa
    42901 caacgtatgc cataaaccgc tttcagactg ataagttttt aatgcacgca cttgtgcttc
    42961 aagtgtttcg atcaataatt tgcgcaatgc atcttctttc gataattcta agatttcaat
    43021 gatctctgga atagcaatcg tcaaccagca gtttccacga gcccaaaatg cttcggcata
    43081 gttatgattt ccttcaaacg tccagccgtg ataccacaat cctgttcgtt tatccatcaa
    43141 gtatttgata tggatcataa actggtaacg agcttcttct aaatattctg ggcgattcaa
    43201 cagtttcccg atttttgcca aaggaagcac tgtcatcatc aatgtatcgt cccacaactg
    43261 attcttattt tccggtccat atgtggcatg ctgtaacccg tcttcatttg tccgaggcat
    43321 gtcattcatg acccattctg cccattgttc taaataaggc aaatagcgtg aatctttcgt
    43381 gtcttcatac aagtaagcca tagtcaatag cggtgccatt gtattgacgt ttttgggcgg
    43441 agcgccttct tccatacgat cctcaaacca ttcattgacc acttgataag cgcgaggatt
    43501 ttttgtcatc tggtaatttt tataaatacc atatagaccg acaccttgtg gccaattcca
    43561 cactgtccag cttttgtcat ctactttcag tccatcaaag tccaacaaaa attcaccatt
    43621 atcgtctttg atcgttgtca ggttttcaac gagcaggtca attttttctt tcactaattc
    43681 tttaggtaca aaaatctctt ctttaataat catctttacg ccaccttttt aaacgctttc
    43741 attttatatc cttaatatag cagtaatacc gtccactata aatatcgctt tttgaacaaa
    43801 aactgtctaa aattgaccta aatgttaaat aacaaaagta actttcagtt acttggaaat
    43861 taaaaaaaga acttggagaa acaacgtttt ccaagttctt tttcatctat tttcttatct
    43921 tttttctacg ctttcttttg cttatccgtt gtaagcatca atgatgatct gtttcaattc
    43981 agagatcaat ggttctttcg gattagctgt cgtacattgg tcttcgtaag ctaattcagc
    44041 catacggtct acggttgtat ctagtgtttc ttgtgtgact ccttgagctt ttagactcat
    44101 gttgatgccg acagattttc ctaattcata aacagccgtt gctaaagctt cgactaattc
    44161 ctctgttgtt tcgcctttca gacctaagaa ttttgcgata tctgcgtaat ctgtatctgc
    44221 acggaaatag tcatatttag ggaacatcgc atgtttttgt ggatcttttg cattatagcg
    44281 gataatatgc ggtaaaagaa tcgcatttgt ccgtccatga gggatcccgt attccccgcc
    44341 gattttatgt gcgactgagt gacaaatacc taggaatgcg ttagcaaacg ccataccagc
    44401 cattgtagaa gcgttgtgca ttttttcacg tgattccata tcaggtgttt ttactgattt
    44461 ttctaaatag tcaaagacta acttgattgc ttgtaggctc aatccacgtg tataatctga
    44521 agccatgact gaaacatagg attcgattgc atgtgttaac acatccatcc cggtatctgc
    44581 tgtgacagat gctggaactg acatgacgaa ttgaggatcg acgattgcga catctggcgt
    44641 caatgcataa tctgctaacg gatatttcac atgtgtttca ctgtcagtga tgaccgcaaa
    44701 tggcgttact tcagaaccag tccctgatgt tgtcgggata catacgaatt gtgttttttc
    44761 tggtttgtcg atcttatatg tccgtttacg gatatccaag aatttttgtt ttgcaccaaa
    44821 gaaagatgtg tctgggtgtt catagaacat ccacattccc ttagctgcgt ccattgcaga
    44881 accgcctcca agagcgatta ctgtatctgg cttgaagtct gccatcagtt tcgttcctgc
    44941 gtatacggta tttgtcgatg ggttcggttc aacatctgag aagacttcga tcttcacatc
    45001 atttttacgt cgtgccaata cttcacgaac tgtatcgcag taaccgaatt ggaccatacc
    45061 agggtcacaa acgatcatga cacgttcaac gttttccatt ttctctaagt acaatagaga
    45121 gttcttttca aagaagattt ttggcggtaa tttgaaccat tgcatgttat ttctccgttt
    45181 cgctacagtt ttgacattga ttaagtttac agcagagacg ttacgagaaa cagagttctt
    45241 accataagaa ccgcatccca aagtcaatga cggaatcatt tcgttataga tatcaccgat
    45301 gccgccttct gcagatggtg tattcactaa aatacgacaa gctttcattc gaagaccgaa
    45361 tttgacatgc aactcttcgt tttctgaatg gataactgct gtatgtccta atcctccaag
    45421 attcaacata ccttcacaca aatcaaacgc atggtccgtg ttgttagctt tgatcatggc
    45481 aagaactgga gaaagttttt ctcttgatag cggataatct gggcctacgc cttccaattc
    45541 agcaatcagc attttcgttc cttttggtac actgattcct gccaattttg cgatttccat
    45601 cgcagaatgt ccaacgattg atggattgac cgcatatttt ccttcgttca tcactgcatc
    45661 ttctaatttt tgcaattcat ctggttttac gatataaact tggtgtgctt ggaattctgc
    45721 ttttactgct gcatagattt ctttatccac gatcacagct tgttcagaag cacaaatcat
    45781 tccattatca aatgttttcg aaacgatcaa atcgttcact gcacgtttaa tttttgctgt
    45841 tttttcaata taagctggta cgttacctgg acctacacct aaagctggtt ttcctgtaga
    45901 gtaagcagac ttgaccattc cagctccacc tgtcgctaag acgatcgcga tacctggatg
    45961 gttcattagc atagaagtcg cttcgatcga aggatgttcg atccattgga tacaattttc
    46021 aggagctccg gcagcgatag cagcatcacg taccactcgt gctgcttctg cagaagattt
    46081 ttgggcactt ggatggaaag caaaaacgat tggatttctt gttttcaacg cgatcattga
    46141 tttgaaaatc gttgtggaag tcggattcgt tgttggagtt actccgcaaa ccacaccgac
    46201 tggttcagca atttcaatca accctttttg gacatcttca ttgatcacac caactgtttt
    46261 atcatgtttg atattatgcc aaatatattc ggacgcatac atatttttga ttgctttatc
    46321 ttcgtaaaca ccgcggcctg tttcctctac agccatcttc gctaatggca tatgttgatc
    46381 caaagctgcc attgccattt catgcacgat atggtctact ttttcttgat caaagctttc
    46441 catttctttc aatgctgcat ttgctttttc tgccaaatca tcaatcattg cttgtacgtc
    46501 aattgtcttc gttttttctt tttctattac tttagccatc attatcctcc taatgggtca
    46561 tggttatttg ttaaataatt cacatgtata tcatacaata tttatttttc tatgtaaaca
    46621 cttttttgtg atttttttca cagttatttt taaatataaa attgctttat ttacaggtgt
    46681 ttgtatagaa aaatatataa agttatttat tattatttat atgacacacc cgattattca
    46741 atattgagca atatatccca tgctcttatc tctttctttt ttgaataaaa aatgaggtag
    46801 gacatctttc tgccctacct cgtctttaaa taagctttga tacttatttt tcttccttct
    46861 cttctgtctc ttccagcgtt tctgttgttt cagtttttac ttcaactgtc tcagctggtt
    46921 cttctgttgt ttcaacagta gtcgttgcat catttgttac gacagtccct ggtttgaccg
    46981 ttttgattgc tgcacgatcg tactcaagga agatcccttc gcagtctaaa acaactgtcc
    47041 gtttgtcatt gtcgatttct gaaacaactc catgtaatcc gccgatcgtt acgactgaat
    47101 cacctggttt catgctatct aacaagtttt gacgttcttg ctgttgtttc ttttgcgaac
    47161 gtgacataaa aaaccacatt gctaatagcg cgataaacat cacaagcatt ggtaatgttc
    47221 ccattttttt cacctcacta attctgtatc tacaaaaaac actttagcag aaaaatgctg
    47281 ataacactag ttttttactt aatttttaaa agattttcct ttagaagctt tttgcgtttt
    47341 ctttattgaa cccgtattct tcaaaaaagg cttctctaaa ttcaagcaaa ttatcatcca
    47401 tgattgcttg acgtacttgt ttcattagat tcaacaagaa gtataaattg tggtaagaag
    47461 tcaaacgaat cccaaatgtt tcatcacatt tgatcaaatg gcggatatag gcacgtgtat
    47521 agtttttaca tgtataacaa tcacatttct catcaattgg acggaaatca tgggcatatt
    47581 tcgcattttt cactactaga cggccttgag aagtcataca tgtgccattt cgagcgattc
    47641 gagtaggcaa gacacagtca aacatgtcta ctccacggat aacaccatcg atcaatgaat
    47701 cagcagcacc gacacccatc aagtaacgtg gtttgttttc ggggatcaac ggtgtagtga
    47761 attctaatac acgattcatt tctgatttag gttccccgac agataacccg ccgattgagt
    47821 aaccagggaa atccatcccg actagatctt tcgcgctttg acgacgaaga tcttcaaacc
    47881 ctgctccttg gatgattcca aataatcctt gacggtctgg attagcatga gctttcaatc
    47941 ctcgttctgc ccatcgagac gtacgttcta ctgatttttt cacgtagtcg taactttcat
    48001 cgaatggtgg acattcgtca aaactcatca tgatatcaga gcccaattta ttttggatgt
    48061 tgattgcttt ttctggtgat aaaaacatac gcgaaccgtt caagtgattt ttgaaatgca
    48121 cgccttcttc ttcgatattc cgcatatcac ttaatgaaaa aacttgaaag ccgcctgaat
    48181 ctgttaaaat cggttgatcc cagttcataa atttatgcag tccgccagct tcttctacta
    48241 agtcttcacc agggcgtagc cataaatgat atgtattact taaaataacg ccagcaccca
    48301 tttctttcaa ctcttctggg gacattgttt ttactgtagc taatgttcct actggcatga
    48361 acattggtgt ggggaaagtt ccgtgtggcg tgatcaattc ccctaaacgc gcgccagtat
    48421 gtttttcttt cttgattaaa cgatagcgaa tggcaggttg cgtcattcat ttccctactt
    48481 tctatataaa atatcttgac aactcccacc atcataatcg tttcaagtgc tttttgcaag
    48541 ttccctcggc ttccttctac tttatttaat attctttttt ttatcctttt tttatgaata
    48601 acaaaaaaaa gaaaaacatt atgacagaaa tattttttga tacatggtat attggtgtta
    48661 ttaaagaaaa ggagggaaaa atcatgcaat cttctgcaga attaaaacgc caagcaaaag
    48721 agagtctaaa aggacgttgg ggacaagctg ttttactaaa tctaatccct acattgattg
    48781 gtattgctac tattcttctt attatgattc ctattatctt gtttgccacc accatatatg
    48841 atggatcagc gagcgtctca gaagcgacaa cttcaggagg cggtagttca ggaggcggtg
    48901 gcggaattat ttccagcatc attagcgctt tgttcatgag cggtatttct tggacttatc
    48961 ttgatatttt acgtggacaa aaagatcaga tcgaaccatt caaagatgca tttcgtggat
    49021 tcaaaggttt gtttatcggc ggagtgatca gcttagctgt gctgatctcg atctttacaa
    49081 cattatgggg tttgctatta gttattcctg gaatcattaa aagctattct tattctcaaa
    49141 gctattttat ttactacgat atcgtccaag aaacaggaca aacacctaaa gtactggata
    49201 cgatcactgc aagtcgaaaa ttgatggatg gttataaagg acaacttttc tggttagatc
    49261 tttcatttat cggctggcat atcttagcat tagcaactgc tggtattggt tatctatggc
    49321 tcagcccata catttctgca acaaaagcag cattttatga acaattgcca aaagatattt
    49381 aaaagagagt gtgacttgtg accgaggggg tggcaggaga acaccgttta tcgagaggca
    49441 gtaaaagaaa cattcagccc attagcaaaa aggaggtgtg acaacattca tgtcacacct
    49501 cctttttgta tagttccagt aaaaagaaaa tcaacttaga aacagttaat cattcctctt
    49561 cttctgcttc cggtaatcga tggaacttga tcagttcatt caccgcgatt ggtacgatag
    49621 ataaaatccc taccaagaac cagtgattca aactgatgtg tactaggccg aatagttctt
    49681 gcgtaaatgg cagcaaagca acagccgttg taatagctaa tgccagtaac gccatttcta
    49741 ccaaagcttt attggtcgct aaattgactt tgaagatcga ttggctgctg cgtacattga
    49801 acacatgcag aatcgatgaa taagctaaga tcaagaatgc aacagtttga ccgacatgct
    49861 gacttgcgtc tacccatggg ctgatagtat cgacataact acctaaataa taaccaaaca
    49921 aggttacgat ggtgaagacc cctgcattta tggcaatttt ttgcaataaa cctcgagcaa
    49981 agatcccttc atttttcgga atgggtggct gatccatgat gccgtgttcc gctggctctc
    50041 ttcctaaagc aaatcctgga agtccatcag caactacatt gacaaacagt agttgcacag
    50101 ctgtaaatgg tgctccccat cctaacagca tcgcaatcaa aacaataaag atctccgaaa
    50161 tattacagct tagcaaaaag ttgatagctt tacgaatatt ctgataaacc gaacgtcctt
    50221 gactgacagc gtctacgatc gtcgcaaagt tgtcatccgt caaaatcata tctgcggcac
    50281 tttgcgccac atctgttcct gtgatcccca tggcacaccc aacgttactt gctttcaacg
    50341 ctggtgcatc attcacacca tccccagtca tcgctacgac tgcacccgta cgttgccaag
    50401 atttgacgat ccggatcttg tcttctggcg ttacccgagc atagacagag agagctttga
    50461 cacgcgcatc taattcttcg tctgataatt gatgcagttc tgatcctgaa agtgcttctg
    50521 acggatcatt caagatacct aattctttcg ctatggcact ggcagtcacc acatgatctc
    50581 cagtgatcat gactgttttg atgccagcct ttttcgctcg cttgattgct cctttacttt
    50641 ctggacgtgg tggatcgatc attccgatca gaccaatcaa acgtaagtct ttttccagtg
    50701 cttcagaaga aatatcttgc ggttcttcgt cataagtagc ataaccaaca gcaatcactc
    50761 tcagtgcccg tttaccaaag cgatcattaa cgatcgccgc ttgttctaca tcgcctgaac
    50821 taaagcgcgg agcaagaaca tcgaatgctc ctttggtgat tgagatgtat ttttcgccca
    50881 tttggtgaac tgttgtcatc atttttcgtt cagaatcaaa aggaagctcg tttactcgtg
    50941 gatatttttc ttctaattct gcctttgtat gataattctc ttcaacagcc cttacgatgg
    51001 ctacttctgt tggattacct ttgataacaa ggtcgtcatc ttcttgctcg accgtcacat
    51061 ctgtacatag tgcagccatt ttcaatattt ccatcgcgct gttcgtcatt gaatcttcga
    51121 tattcgttac ttcatcttct ttgctccata cccggcggac gcgcatttca ttttgtgtca
    51181 gcgttcctgt tttgtctgag cagataacat tagcggttcc tagcgtttca actgctggca
    51241 actgtcggat gatcgcatgt ttcctcgcca tcttctgcac accgtatgca agtgtcaacg
    51301 taacaataac agtcaaggtt tccggtacag ctgcaacagc caaggaaatc gaagtcatga
    51361 acatctcaag gagtggttct ccttgcagtt caccaatcac aaatactaaa gccgcagccg
    51421 ctaaagcgat catactgatt cgtttgccta gctgattcaa tcggacctgt aaaggtgttt
    51481 tttgcatagt attttcgttc aaaagatccg cgatcttacc catttctgta gccatgccaa
    51541 tggcagtgac gatcgctttc ccacgacctg cagcaaccgt acatccttta aataccatat
    51601 taagttggtc acctaatgac tcatcttctt cagcaataaa tgctgcatct ttttcaactg
    51661 cttcactttc tccagtcaac gccgattctt ctacacgtaa ttgtgatgct tcgatcaaac
    51721 gggcatcggc agaaatagca tcaccggact ctaaaacaag aatatcaccc actaccagtt
    51781 gctctgactc aacagtggtc actttgccgt ctcgtatgac agttgccgtt tgtttattca
    51841 tatcttgcaa ggattccagt gctttttctg cgtttccttc ttggacaatc gccaataccg
    51901 agttgatcac aacgatagcg atgatcagca gtccttcaaa taaatcccca tgttctgtag
    51961 caaatgcggt ataaaaggaa atcaccgctg ctacaagaag gatgatcgtt gtaaaatcgg
    52021 acaagcttcg aaagaatttt ttgatcatcg attctttcgg cgcctcatcg aatttattca
    52081 atccctgctt ttttcgccgt tcatccactt cttgtgaaga caacccagta tctggatctg
    52141 cttctgttac cttctttact tcttctattg tctgcttgta ttcttccatc ctattcctcc
    52201 tttaaaatct tcgtacaaaa aaaggtactt attttactat aacatccttt ttttatttac
    52261 ttcaaataaa gggcttatcg attatttgtt aagaaagcgt aaaatttaaa gtgcttatat
    52321 ttgcaaacgc taccaaagga tgctattata tagatgtaag gaaggaggat accatcaaat
    52381 agacagaaga atttctcgat agaacagtgt aagcaaacaa agttgttaga agtacaggtt
    52441 tcacccagac atgcgtgtag agtacaaacc tataaatagt gaatgcgtat ggatgtttgg
    52501 atcacgaagt atccgaaaca agaagtaatg cgatacgtaa caattgaata acgtaaacgt
    52561 ctgaaaattg aataggaaca agagatgttt caaatgttga agatgtaacg aaaacaaaat
    52621 ttttgtttaa catgaagaaa ttcaacaccg tgctttgcat gtatgatgga aagttacaat
    52681 catttctgtt tatttgaatc cttccgaggt acaagaaagc cgagcttatc gagagctcgg
    52741 ctttttcttt gtcataaaat ctttgtaaag cttttttgtt attcaaaact agcggctttt
    52801 cataacctta tttcacgaac atcgcatctc caaaactaaa gaaacgatag cgctcttcaa
    52861 tcgcatgctg gtaagcagat aaagtcaatt ctcttcctgc aaaggcacta actaacatga
    52921 ctaaagtcga ttttggcaaa tggaaattag ttgagaaagc ttctaccact ttgaattcat
    52981 agccaggcgt aatgaaaata tcagtccatc cgctgtctgc tttgatttct ccattaaatt
    53041 tcgttccaat cgtttctaat gttcgaattg aagttgttcc gacagccacg attttcccgc
    53101 catttttacg tacttggttc aatcgctcag ccgcttcttc cgtcaaacgg tagaattcac
    53161 tatgcatatg gtgttcttca attttatcta cgctgacagg tcggaatgta cctaacccta
    53221 catgtagtgt cagatagact aattcaacac cctttgcttc gatctcatca agtaattctt
    53281 tcgtaaaatg caatccagct gttggcgctg cagcagaacc attttctttc gcatagacag
    53341 tttgatagcg atctgggtct tccagacgtt ctttgatata tggaggcaat ggcatttctc
    53401 ccaatgattc aagaatctct agaaaaattc cttcatactc aaagtcaatg atccgtccgc
    53461 cgtgttccaa ttcttctttc actactgctt gcaatctgcc atcaccaaaa gagattcttg
    53521 tcccaacttt ggcacgtttc gcaggtttga tcaatgtctc ccacgtatct ccttgtgtat
    53581 tcgttagaag aaggacttct aaatgcgcac cagtatctgg tttttctcca tataaacgag
    53641 caggcagaac tcgtgtatta ttcataacta gcgcatcacc aggctgtaac tcttcaatga
    53701 tttcatggaa atgtttatct tccatctctc cagttttccg atccaaaaca agtaaacgag
    53761 aatgatcgcg gtcttttaat ggtgtttgtg cgattaattc ttccggcaag tcaaaatcaa
    53821 aatcttctgt tgttaacata tcgtcactca ctttctatca tgtgcttcat cattctatca
    53881 tgtttttcgt tctgttggca aaatcagcac tttttcactt ctattttttg ttttcctaaa
    53941 taaaaaaact accctatttg tattttttca ttgttttagg catactagta atagatagtt
    54001 cttcattgaa aatagaaaaa gaggtggcac catgattgaa tttcaaaatg tgtcaaaaat
    54061 ttataaaggt ggaaaagtcg ctgtagagga cgtcaatctt tcatttgaaa agggtgagtt
    54121 catttgtttt atcggtacga gcggaagcgg aaaaacgacg acgatgcgga tgatcaaccg
    54181 aatgactgat ccaacacaag ggaaaatttt gattgatgga aaatccatcc aagaaattga
    54241 tccagtggaa ttgcgacgtc agatcggcta tgttatccaa agtattggat tgatgcctca
    54301 catgacgatc cgtgaaaata tcactcttgt ccaaaaattg ttgaaagtca gtcaagaaga
    54361 acggaataaa acagctgaaa aaatgattga tcttgtggaa ttgccccgtg agatgttaga
    54421 tcgctaccca catgaattat ctggtggtca gcagcagcgt attggagtcg ttcgtgccct
    54481 tgcagcgaat caagatatca tcttgatgga cgagccattc ggtgcgcttg atccaatcac
    54541 tcgtgattcc ttgcaagacc ttgtcaaaga tttacaagag cgtttgggaa aaacgatcgt
    54601 atttgtaacc catgacatgg atgaagcgat taaactagca agccgtatcg ccatcatgag
    54661 tgaaggccgt gtgatcaatt tgatacacca gaaaatattt tacgtcatcc tgcaaacgat
    54721 ttcgtagaag agttgattgg agaagatcgc ctactacaag ccaagccaaa tgcgacaaga
    54781 gtcggcgaag ttatgctaaa tacagcaatc acgattacac cggaaaaatc attacaagaa
    54841 gcaatcaaac tgatgaggga aaaacgtgta gatacgttgt tagttaccga taattcgaat
    54901 gtattaaaag gatttatcga tgtagaaacg ttgaataaaa aacgaggaaa agtatccagt
    54961 gtcggcgaca ttttgaataa acatgttttt tacgtaaaag aatccgccta tcttcgtgat
    55021 accttgcaac gcattttaaa acgcgggctg aaatacgtgc cggtcgttga tgaacagaac
    55081 aaagtcgtag gtatcctgac tcgtgcatca ttagtggata tcgtctacga tgtgatttgg
    55141 ggagaagatc ccgcaactac tgatgttgca gagtcagcta ctcctgaaga atctaaggag
    55201 gtctgaccta tgcagcagtt ttttcatcag cacggttcag aaattctctc aaaaggtttt
    55261 gaacatcttt atatttcagg acttgctttg atcattggta tcatcattgc tgtaccgctt
    55321 ggtgtcttac tgacacgttt tccaaaagct gccacgattg tgattggctt aaccagtgcc
    55381 ttgcagacaa tcccttctct tgctttattg gcattgatga tcccgctatt tggcgtaggt
    55441 aaattacctg cgattatcgc actctttatt tattcattat tgccgatttt acgtaatacg
    55501 tacattggga tgaaaaatgt cgattggaat tatcgggatg tggcaaaagg catggggatg
    55561 actgagttcc aatccatttt ttccgttgaa ttgcccattg ctatgccaac gatcatggct
    55621 ggtattcgtt tagctgccgt ttacgtgatt gcatgggcta cacttgcctc ttatatcggc
    55681 gctggtggtt taggcgattt gatttttagt ggactgaata attaccaacc agatctcatt
    55741 ttggcaggta cgatccctgt aacaatttta gcactattgg ctgattggct tctaggtctc
    55801 ttggaacacc ggctgacacc gatcgcactt agagaggaga atgaagaatg aaacgtatac
    55861 taaaaatgac catggttctt ttctctcttc ttatacttgc gagttgttcc ttccctggtc
    55921 ttgccagcaa tacagatgaa gacaccattt cgatcacagg tggaatcact tcagaagcac
    55981 agatcttagc aagtctagtt gccggaatgg ttgaacatta tacagataaa aataccgcaa
    56041 tcatcaacaa tctggctact acaactatca accatcaagc gatgatgaac ggagatgctt
    56101 caatttcagc ggctcgctac acaggaacag atttaacgac tacattgaac cttcctcctg
    56161 aaaaagatcc gaaaaaagcg tttgctaccg tgaaagatga atttgagaaa agatacggtc
    56221 aaacgtggtt cccgtcctat agttttgaaa atacgtatgt ctttcttgtt cgaaaagaca
    56281 ccgcacaaaa ataccatcta tctaaagtca gcgatctgaa aaatgtagcg gatgaattag
    56341 tagctggtgt agatacttct tggatcaatc gtaaaggaga cggttatgac ggcttccaag
    56401 aaacttatgg cttctccttc aattcgatat tacctatgca gattggactt gtttatgacg
    56461 cagtcgaagc aggaaaaatg gatattgttc ttggctactc tacggatgga cggatcgcca
    56521 gttatgatct agtcatgttg gaagatgatc gtcaattctt cccaccatat gatgctgctc
    56581 cagttgtaga caacaagata ttagctgata cgcctcattt aaaagaagcc ttaaataagt
    56641 taggtcatac catcagtacg gaaaaaatgc aggaattgaa ctacgaagca gataataatc
    56701 tagtggaacc atcagtagta gcacaacgtt tcttacaaga aaaccactat tttgaaggga
    56761 agtgaagcaa ttggataaaa tgaatgtctt tcaacaattt ttctattatt tccaggaaaa
    56821 tggctcctat atctttgcac aatttatccg tcacttcctg atttctatct atggtgtcct
    56881 ctttgcagca gttgtcggga ttccggttgg gatcatgatt tctaggagac gtaaattagc
    56941 aaactgggtg attcgtttgg cgaatatcat ccagacgatc ccttctctag ccatgatctc
    57001 cattttaatc attggattag gcctgggagt caatgtcgtg attgttactg tatttttgta
    57061 ttccctctta ccgatcatca agaatacgta taccgggatg atccaagtag acaaaaacat
    57121 ccttgatgtc ggcaaaggca tggggatgac tgctagacaa cgactattca tggtagagtt
    57181 accactctct gtttctgtta tcatggcagg cataagaaac gcgttagttg ttgccatcgg
    57241 gataaccgcg atcggtgcat tcgtcggtgc tggtggtctt ggagatatca ttatccgagg
    57301 aaccaatgca acagagggca catcgattat tttagcaggt gcattgccaa ctgcattaat
    57361 ggcgatcatc acggactggc ttttaggtat tttggaaaga cggctagatc cagccagccg
    57421 tacatcacgc tgatgttatt gtaaaaaaca aaagcttctg cgaccatttg ttggtcgcaa
    57481 aggctttttt agttctgtca tttttaaggc aataatccac tctgattctt ccctccttat
    57541 gggcaaagag ttgcttttct tagctattta tccattccgt atactccaac ttcatactgc
    57601 caacgggttc atatctgcat ccaccgacta agtttttttc ttatccgcta aggcattttg
    57661 ccaatccatt ttcccatcac tcgtcatgga attcatacca catgatctct aaatactcgt
    57721 ctgcttgttc tttgaattgg gcatcaattc ttacatcctt tggcgtggct ttcatttaag
    57781 ccttttccat cagtcctcga ttgttcgatg ccttcagctg catcatcaaa actggtgact
    57841 gccgtatcgg taacttcgat catcttttat acaatcggga acttgccatc ctcatccttg
    57901 gctaaaaaca tatctagcca ttccagcttc tcgccatggg aggtttgcgg ttcctaaaac
    57961 cggtacacga ttcttatgga ctgcatccgt cgcaactaga cttggcgata cgatgatcct
    58021 tcaccagaag agcacccccg taaaccaatt gatcgatata ttgccaataa gaaaagacat
    58081 tggcgtaaaa gatatcgatc cctcgtgatg cattgccgtt gatactgcta ttcatggccg
    58141 aaagcgccac gactttaact tcttccgttt gagtgacatt catgttcggc aatgtcgctt
    58201 tggatacccg ctctgctaaa ggaacgacac tggtattgta tttcgtatct gtatcttttc
    58261 caaaagacca tgccaacgaa tcctctggga accaataaga cgactccggt tgattgtcca
    58321 ttgctttttt caacatactt ttggctgttt ctcgataaac gacatttcca attgtcttcg
    58381 cctcactttg gcgataatcg atggtcgttg ccactgccaa cactaacaac gatgctccaa
    58441 ttttactgat tttccttgtc acacttcttc ctccttgttt tacataaacc cgtcaacatt
    58501 ccattcctaa actcaaacaa tgacccttca aaggtggaga tataggaaca aattaaagaa
    58561 atcatgcaat aaatccaaga aggttggttt tagaacaaaa aaagagtctc ctttttgggg
    58621 agactctttg ttaactatct aaaaaggttg gctcttctca cttcactcat aatgtgtcca
    58681 ggcagaataa atttctacaa ctttattttc ctcatcaact ttgtaaacca ctcgatgctg
    58741 tctattcagc ctgcgtgagt atctgccttc atgtgtaggt ctcagctttt caaaagactg
    58801 cgtgggcata tatggatctt ccttcaatgt ctgaatcact tcttcaaatt gtttctttaa
    58861 attcgtttgc ttgatttttc ttaaatccac tttcgcagag tttttgattg cgactgtata
    58921 gttactcatc aaagagcttc ccaatcaata tcatcgatat tcgtaaagct actgtcgtct
    58981 ttttcgcggt ctcgtacttt atctaaagta cctgtttgct caagaaaaag ggtttcttga
    59041 atcgctctcc agtcttccag cccaatcaat acagcattgt ttccactacg atcactaata
    59101 atctcgattt cagtatgatt ttcatttacc tctttcaata actgataaaa atttttacga
    59161 gcagtgctag gattcatcgt tgtattagcc attgtctctc ctcctttttc tgatataatt
    59221 atagcgtact tgattaagta cgtcaaaaaa atacaataaa gcacttaaat tcagcaaact
    59281 tttcctcttt tttacataga gaaaaagacc cctttttagg gaggatcttt gtccacgctc
    59341 acttcttact cctttacgac tagcggtagc caaacgtaaa gtaattggta acaacgtatc
    59401 atctttagca aaggtcgaat ccaaagcctg tgagtctatg caacaacacc aatacacgaa
    59461 ggttcctcgt tgcagtgtga cttgattgat atcttgaata acctgaggat acgcacgaaa
    59521 gatttgtaac ggttattcaa aactgatttt ggccgtcaag tcttctactg cctcaaaaat
    59581 gattgcctct ttcgtctcct gtcattcatg ttcactatcg atttgatact tgcttagacc
    59641 gttgggtttg tgaatcacca attaaaaatg gcactgagtt atggtaacaa aaaatggtca
    59701 cttgacgagg ctgagattcc tacttatgaa gacacatggc acttaagagt cgaggtaaag
    59761 gaagaagctg aaaatatagg aggctgtaca ttatttggca aaggattcgg aaattatgat
    59821 caagacatca aaatcaaaat gttttacagc taaataggaa gaataataac atttcatacg
    59881 ctgttcccat ctttaatggc ttatagaggg cacctttagc tgagaataag acaaaacaga
    59941 ccctctagct tcaattaaga gctagagggt ctgtttttga ttttaaaact tggtttattt
    60001 cttcaaatgg tagctatagg tgctgacaac gatattttca cgccaagaca atcgcaatct
    60061 taaccgcaaa cttgtttggt tatggagaat attctgccag cgtctgtttg gtacaaattg
    60121 aggaatcaac acagtagttg tatagttttg tttcgctgca tttttactta cgatatctac
    60181 ataacggata attggatttt caatcgagcg ataagaagag tggacgattg aaaaacggac
    60241 atctgggaaa tgctttttaa attctgcttc gatttctttt tctttttcga catcttcgtc
    60301 tagcgaaaca tgcatcgcaa cgacataatc accgatcgaa cgtgcgtaat tcaacgcacc
    60361 gatatttacc cgtgtcacat tcccgactaa tacaagaacg gtattcccgt cataatcatg
    60421 tagttttgca tcattttcta aacgaagctg ttctgctact tttttataat gatcatggat
    60481 cttataaaaa atgaacataa cgattggcat aatgatgaag aaaggccaaa tgtcccctaa
    60541 ccgatagaca aacaaaatcg caatgattgc atatgagatg aacgcacccg taatattggc
    60601 aatcgatttg cttaaccatc tttttccttc ttttttccat ttgacgacca tccctgtttg
    60661 agataaagca aatggaatga acacgccgat agagtataac ggaatcaagc gttctgttga
    60721 gccatggaaa ataaacagca atacgatcga acctagcgct agtgtgataa tcccattgga
    60781 atagcctagt cgatccccac gatcttgata catgtgaggc atgaatttat cttttgccag
    60841 attgtatgca agaactggaa aagcagaaaa accggtgtta gcagcaactg ctaaaatcag
    60901 cgctgtagca aattgaagga cgtaatacaa aataccatgt ccaaagacag ctttaccaat
    60961 ttgagacaaa acagtgactt ctttttcagg aacgatccca taccaatagt tgataaatgt
    61021 gatccccacg aagaagaaac ctaagatcaa tgccatcatc gtcaatgtag cagcggcatt
    61081 ttttgctctt ggcttcttaa agaatggtac agcattacta atcgcctcca ccccagttaa
    61141 agaggaagaa ccagaagaaa atgctcgtaa aatcaaagcg atagaaacac ccggcacagc
    61201 cgctcctgga agtgcagtag cttgcaatgg cacagcacct gtcacgatat tatataaacc
    61261 aacaacgatc agtaacgaga tcacaaggat aaatgtgtac accggaaata ataggaacga
    61321 tgcagattcc ctcagcccac gaagattcag catcatcagt agcaaaacga ttgtcacaga
    61381 aatagcgact tgatgaccgt agagtgctgg caccgctgat gtgatcgctt cagcacctgc
    61441 tgagacagat actgctactg tcaacatgta gtcgatcaat aaagagccac cggaaatcaa
    61501 gccagcattc tttccaagat tctcactgct gacgacatat gctcccccgc catgaggata
    61561 agcatggatg atttgacgat atgatagcgt taatgaaatc aataaaataa taacaaaagc
    61621 ggcaatgggt agcgaatacc agatggctgc agcagacaaa gcgactaaaa cgacaacgat
    61681 ttgttccgta ccatatgcaa tagatgataa cgcatcagac gacaataatg ccaaagcagc
    61741 aaatcgggtt aatttgtgct catcattttc agcagatttt aaaggcttac ctactaacaa
    61801 cctttttaag taatccaatt tctaaactcc tttacacaca attttacttc aagttttata
    61861 gtcgaaaatt tatagtaaac aagatgttat agtacgctca ctgaccttaa aagtcaataa
    61921 actttaagaa aataattgga aaaaaacaga aaaatatcaa gcgctttttc aaacgcttta
    61981 atacagcaaa aatctaacat ttttttatgg gctttttctt tgaattctat aataaaagga
    62041 tagaacttga cttagaaaat caagttctat cctttttgat atcttaactt ttggaagaga
    62101 gatgtaaggc tgctttctac ccatcattct tactactcga agcatagcgc agttgtcaca
    62161 acctcttgat aaacggtgtt taaaagcttg catctgcggt aataagccca accaaattaa
    62221 aaacataaga agctgttttt atttggtcgt tcttattact tgatgcagag cagctttttt
    62281 acaacctctt ggtacacggt gttcaatcag ctgaccctcg gtattagctc aaaaaaacgg
    62341 caaaatatga ggaactattt ttccattttt ttctctaata ctcaggtcaa aacactgatt
    62401 tcacaacctc tttttttaat gaaaaatatg gctctcatgc gccgcttctt tgaatttcgt
    62461 cattttttct tcgatgaacg gatagattgc cgttcctacg attccaaaga caacaaacaa
    62521 accgatcatg atccagattg ctttcgtagc atttggccaa taaattcctc ctgcagattc
    62581 ccgtaacaag tttaccgcat gagtaaatgg caagaacgga ttgatcattt ggaagaattt
    62641 ccctgagact tggatcggat agttcccgcc tccgccagag atcgacagta ctaagatgat
    62701 aatagcgatc cctttaccga cattatcgaa taatgcagcc aagacataga cgatcatcat
    62761 gaacgctaag gcgatcaaga cagcaaatga cacgctgtag accggatttt ggacatctac
    62821 tcctagtaag aaaatattcc ctaatgtaac gatcaagctt tgcgcaatcg ccattgtcaa
    62881 aaatgtcagc atacgagcaa cgaattgttc tcgtttcgta aaattgtttc ggtctttctt
    62941 tcctaaatag tattctgtcg tagcaacact tgaaagaaga acagcgccga cccacagaca
    63001 tagtgcagta taaaacgggg tgctagctga accgttattt gcgattggat aaagcgcatt
    63061 ggtttgtagc tcaacaggtt gtgtaaagaa gtcactttct tttgttgcgt ctagtttcaa
    63121 taatttgatg acttcgccta gatcgacttc ttgttcgcct tttcggatcg cgtctgctgc
    63181 tttttggata ccagctttga tatttggcca gtcattgttg atcaagtccg cagcagcgtt
    63241 cacagctgtt tcgacttctg gcattttttc atttactgtt gtcaatgtac cggtgatttc
    63301 attttttagt gctggccaat cattttggat aaaatcagcg gccaatccta atttttgctg
    63361 aatgatcggt aattcattgt tgtataggtc tgccccttca ttgatgccat tgacgatggt
    63421 atccatattt ccattcagca ttgtattggc atcatggatt tcttgtccaa ttgcaggcat
    63481 ttctttttga tatttttcta aaattgccac tgcattcgtt acagttgctt tcgttgagct
    63541 gagaagcgaa tcaaagtcga tctggtccgc tttgctcagt gcgccttgtg cagtcccaat
    63601 cgtatcgatg acttggtcta gtagagaagt gacagtggaa ctgatttgac ctgtattgat
    63661 accagcaatg atgccattga tattattaac aacggcatca atttgatcta gcaattcatc
    63721 aatagccttc gtgtcttcat tttgaacagc tgtgttcaaa gcagataggc ggttttgcag
    63781 attgcttagc aagggtttta attgatttag ctgatcaata attggctgta atttcgtatt
    63841 tccagcactt gtttgcaatt tagtcaggaa ctcgaccagt ttatcgattg cattttgttg
    63901 ttgagatatt ccgtcaataa agccgttcaa tacattgctg atgtttttct tttcatcatc
    63961 agtcagctta ccatcttcaa tagctgttct tacagtatct attaacgaac ctgtcgttgt
    64021 tgccacttgt ccaattgact tcaatgtaac atctacactg tttgtgatgc ttggtatcgc
    64081 atctttcagc tgagaggcac ctgattttgt ttggtttgct agatcacttg cctgattttc
    64141 taaatttttc acatctggca agatatcttg tacttgttgg atgatcgtca agccttgttt
    64201 tgcttcatcg attccttggt tcattgtctc ttggatcgaa gcaaaatcgc cgtcgatctc
    64261 tgctagttgc ttaccggcat tttggatctc tgggattttt tcttgcaaat caaggatgat
    64321 ttttgcttga tctttcaact caggcatttt gtcattcaat gcaacgactt tttcacccat
    64381 ctcatctact ttagggatgt aatccacgaa ttcatttgct ttattcagtt tttccttgat
    64441 ttcaggtagt tgactttgta attcgaggac ttgttttgtg tagccgtcga tcgtgtccaa
    64501 attttcatct gttgataaaa tcatatcttt aactttattg atacttacta ggttcgtatc
    64561 gatgtcgtaa cctatctcat tgaatacttt caataaagtc gaactggctg ttttgataaa
    64621 ttcatttgtg atttgcgatt ggatcgaact tgctccttta tcggtgattt tcggtgcaat
    64681 cgcattgatt ttttcattta ccgtatattc gatttttggt ttcttgatat caccactagt
    64741 aaaactcagc agatcttctg agaaatcctt tggcaagtaa atacctgcgt aatactttcc
    64801 ggaacggact ccgtcttcta attgttcttt tgaatcaacg aattgccatc ctaattgttt
    64861 atttttatga agcgattcga tgacttgctc cccaatggcc acttctttac cttgaaactc
    64921 tgctggcttg tctgcactgt aaacagcaat tggcagctct ccagtatttc catatggatc
    64981 ccataatgct ttgatgttaa accacgcata tagcgaaggg atgatcatga tcgcgatgat
    65041 cagaagtgtt gcaatcgggt ttttgaaaat ccgtttccag tcaagcaaat ataatcgaag
    65101 cgtatttttg attgactgca tagttctccc ccttcttctt ttttcagctg aattacttta
    65161 ccatgtattt catacttttt tcaatcggct tttttcaaaa aagtcgaatt tttggacata
    65221 tcacggcaat tgtctcattg taatctctta catattgaga aataattaag gattacagcc
    65281 tttactttat catgaaataa aagggaaaga taattttatg ccaaagtttt tatctattat
    65341 acgtatacgc aaaaaagcta aaacattttt tgtctttgcc cctacaaaaa tgtttcagct
    65401 tttttcgttt tttattcctg tatttcttat ttttcgaatg acaggatgat tttcccagca
    65461 ggaggatgtc cttcaactag ctgatgtgct tggatgacat gcttaagtga agcagacaga
    65521 ttcattgaaa taaaaacatg aaaggctcct ttttggtagg ctttgattat gccagcaaag
    65581 gcttctgcat ctagatattc ctttcttgga acaaacgatt cataaaagcc ttcctttttt
    65641 tgccgcaaat ctagatctgg gaggtcattt aatgcaacat acctgccgcc tggtttcatg
    65701 atctggatgc cggtttctcc tttgatactt cctttcgtcg catcgattac aaggtctgcc
    65761 tgatcagcaa attgcagacc tggatttgtt ttatcataag cagcaaatgc tgaagctcct
    65821 aattttttta ccttttcctc atttttactg gatgcactgg ttaagattcg gattcccttt
    65881 tcatggagaa gctggatcag acttgacccg accgcacctg atgctcctag tatcattaca
    65941 gtatctgtcg gctggatttc cgtcaaatgg ttgattagat tataagccgt aattcctggc
    66001 gtgaccattc cggctgcttc ttcccaactc attttatctg gaatttttgc tacttttgct
    66061 gatggcaaca cgacttcttc tccgtaagtc ccgccgactg catggacagc tactcgatca
    66121 cctacatgaa cagttgtgac atctgaacca atctctgtca caataccagc gccatcatta
    66181 cctggtacat aagggaattt caatgttcgt atctctttca tttctcctaa acgcaaggca
    66241 acatcataag gattcacact gaatgctttt atttctacac gaacatgtcc agaaccgact
    66301 tctctgggat gagcatcgat ttcttcaaaa acatcttgtg cttctccgta accgttaatt
    66361 gcaaatcttc gcatggtcac catctccctt tttctttaag tttacgttta tgcctttatt
    66421 ttgacaaaaa aaatgtcttt tcgttttggc gcatgattca aaacaaaata gttgtctttt
    66481 ttcgcgtaac gtgttaaatt atttatctaa aagcgtaaag attacgattt acgctaataa
    66541 aaaataattg gaggaatttg ttgatggcta aaaaatcaaa gattgccaaa gcaaaaaaac
    66601 agcaagaaac gattgaacgc tatgctgctt tacgccagga attaaaagcg caaaaagatt
    66661 acgaaggctt gcgtaaactt cctttagatg ctcgtccaga acgattgaaa aatcgtgatt
    66721 taatcgatgg acgccctcgc ggatacatgc gtaaattcgg gatgtcccgt ataaaattcc
    66781 gtgaattagc acataaaggt ttgattccag gagtaaaaaa agccagctgg taatccaagt
    66841 ctggctgtaa tgtaaaggag gagggcgcat ggaccactcc ttggatcatc aaaaaagata
    66901 cgttcgcttc ttctagcaga aatgctggta ctagaagcag acgtatcttt ttttacgcac
    66961 agctggtcct tttttatatg taaaggctgc atggttactt cgctatattt atttagtaac
    67021 aggagtcagt gcttcgatac ccacactaat tttcaatgct cggtcaactt ctgccataat
    67081 gggtcgatcc aaatggcaga ccttttcttt caatcttgat ttatcgatcg ttctgatctg
    67141 ctccaacagg ataacggagt ctctttctat tcctgttcca gtagctttga tcccaatgtg
    67201 agtcggaagc ttaggtttag ccatttttgc cgttatggcc gcaacaatga tcgtcgggct
    67261 aaaatggtta cctagattat tttgaataac caaaactggg cgtgttccgc cttgctccga
    67321 tcccacgact ggagaaagat cagcaaaata aatatctcct ctttttacca taggatcctc
    67381 cttattcttg atattctctt ggtatccgct gtcctaatcc gcaagccact tcatagtgga
    67441 tcgtacctaa ttgatctgct atatcctgca tagtgatttc tttgtctgca tttttgccga
    67501 taagcgtcac ttttgttccg acaggaaatt cttgaggcaa tcggatcatc agttgatcca
    67561 tacatacacg cccaatcgtt tcacagtagt tcccttctac caatagagaa aaaccctgca
    67621 tctttcgtgg ccagccatct gcataaccga tcggtatcgt tccgatccac tctgcttcag
    67681 gagtgatata tgtttctcca tagccgattc cttcacctgc tgggagtttt ttgacttgaa
    67741 tcaattcaga aaccagctca agtgctggct gcaatggata aacttccggt agtgcgtgcc
    67801 cagagggatt aagtccgtac attgctactc cataacgaat catattgccg attgtttcat
    67861 catgccataa agccgttgca ctattgctga catgtacata tcgaggaagt tcgggaagtt
    67921 ttttcagcac ttctataaag cgttcttttt gcagattcca atatgtatca tctgcctgat
    67981 ctgctgtaga aaaatgggta aataaacctt cccattctaa tacacgactt tctttgatga
    68041 atgcagctgc ctcttttact tcttcaggtg tacaaaatcc gatacgaccc atcccagtgt
    68101 ctgcttttag atgaatcgaa agaggcgtct ctagcttact tttctctaaa acagcagctg
    68161 ctgcttgcaa ccattcccgt gtacctgcag ttactgataa atcatgagca acagctacag
    68221 tcagtgcgtc gtaaggaacc atattcaaga taaggatggg ctgagtaaat ccagcttctc
    68281 tcaactcgac tccttcatct aaatttgaaa cacaaaagcc cgaagctcca cctgcaactg
    68341 ctgcctcagc tgtttcaata gctccatgac cgtatccgtt cgcttttact actgcaaaca
    68401 attcttttcc ttgcggaagt cttgcaactt catttgctac attttcagtt atagcttttt
    68461 tatgtatcac tgctttcgtt gggcggtgcc aagcgacaac catcgttttt ccttctttct
    68521 agtcttccaa aataatttgt gcaaaagctg tttcatttgt atgagtaata ctgacccata
    68581 cattgccttc atgaggtgaa cgcgtcacaa caggctgacc attttcattt tttaaaatct
    68641 cgacatcttg aaaggtaact tttccgatcc cagttcccca agctttagag aaagcctctt
    68701 tgcaagcgta acgcccgcct aaaaattcta cttggcgatg aaaaggcaag gactggaata
    68761 gtttcatttc atcagaggtc aagattcgtg caatgaattt tggtttttct tcgatcagcc
    68821 gagtgatcct aggaagttcg actgcatcga tcccaattcc ttttatcata tgcttttctc
    68881 ttttcaataa atttagaaca ctctcattct accaaattat aaccattttg ccacaaataa
    68941 gtccacaaat aacaaaaatg aaagtttctc ttaaaaaaga gaaactttca ttttatgttt
    69001 aatcgttatt tgaacggatt acaaatccgc gttttttatc attgtgacgt ttaccgccat
    69061 ctttttggct gttattattt ttgctataac cgccttttga tttgtttcca cgataattac
    69121 cgccgtcacg acgattacgg ttgtttccgc caccacgttt gccattttta ttgtatcctt
    69181 ttttctgcat tggcaatggg cgttctggtg tgatcttcac tggcactgca tcagctggat
    69241 cttttgctgt cgtttttagc aaaagtgcaa ctaaatcttg tgcagaatat tcttctaata
    69301 atttatctgc tgtttgcagg tatttatcta gaccattttc tgcaagtttt gtttcgattt
    69361 gttcaactgc agcacctaat tgacctttga atgcttcttt ttcggttggt ggacgtaaag
    69421 tcgtcatccg ttttttcgtc aagttttcaa tcacatgcaa gtagtccatt tcatttggtg
    69481 taacgaaagt cacagacata ccgccttttc cggcacggcc tgtacgtccg atacggtgaa
    69541 cgtagctttc tggatcttga gggatatcat agttgtacac atgagtgaca cctgaaatat
    69601 ctaatccacg tgcagcaacg tctgtcgcta caaggatatc taaatgaccg ctcttaaatg
    69661 aacgcaatac gctcattcgt ttttgttgag acaaatcgcc atggattcct tctgcacggt
    69721 aaccgcgtgc ttctaatccg cgtgccaatt cgtctacacg gcgttttgta cgtccgaaga
    69781 cgattgttaa ttcaggtgtt tgaacatcaa acaagcgagt catgatatcg aatttttcgt
    69841 attcttttgc gcggacatag tattgatcga tcaagtcagc tgtcatttct ttcgctttga
    69901 tcttcacatg atgtggattt ttcatgaatt taacgccaat attcttgata gctggcggca
    69961 tcgttgctga gaaaagtaat gtttgtcttt gatcaggaac ttgtgaaatg attttttcga
    70021 tatcttccaa gaagcccata ttcaacattt catctgcttc atccaaaact aatgtttgaa
    70081 cggttccaag tttcaatgtg tggcggttaa tgtggtcaag catacgtcct ggtgtaccca
    70141 caacgatatg tggacgatct ttcaagccac ggatctgacg gccaatatct gctccgccgt
    70201 aaacggcttg tacacgtact tttttgtcgc gccctaaacg atataattct tcttgtgttt
    70261 ggatagctaa ttcacgtgtt ggtgcgataa ctaaaccttg taattcgtga cgatctggat
    70321 cgattttttc taacattggt aatccaaatg cagctgtttt ccctgtacct gtctgtgctt
    70381 gtccaataac gtcttttcca gctaatgcta gtggaatcgt ttctgcttgg ataggcgttg
    70441 cttcttcaaa accagcgcgt tcgactgatt tcaacaattc tggtgataat tctagttctt
    70501 taaatttcaa atgaatcctc ctatatggtt gttaactgag gatgtagctt ttttgctacc
    70561 ccgtcgattt gttcggtcaa agtgtattgt ttctttttga cagtggccac gcacgttttt
    70621 atccattctt agcccctgtg gcaccaccga aaaatcactt tgcgaagttt aggcattaga
    70681 aaagccaaac gggtcgcgtt cagctttatc attattatga catctggctt caacaagttg
    70741 tttctatggc aaaaccagtc caatttctct tcatctttcg gcaataggtt attctaacat
    70801 agtttttcgt tttctgcaag tttacagatt tttatttcat ttgctgaagt tgttctacca
    70861 cttcaaataa gcccatgctg ttgctgcctt ttagcataat actatctgtt gcttcaagat
    70921 tttgtttgat agcatcaatc aatttattct tttctttttc aaaatagaac acaggtagtt
    70981 gggggtattt ttggttcaat tcttctttta gtgcatgcat ttgttcccca taaaggaaaa
    71041 tcatggcgaa tttctcagga tcgatatgtt cactcatttg cgcatgcata tttaaagact
    71101 ctttccctaa ttccagcata tctgctaaca cagcgattct gcgtcctttt gttggcagat
    71161 ttttaaaagt atctaatacc agtcccatgg ctgttggatt tgcattgtag acatcgctca
    71221 aaatagctgc accatttcct gccgttagcc attcggttct gttttgagtg atagaaacat
    71281 gggcgagccc ttggcgtatc tcaggtatgg acagtccaaa gaagcgcccg atcgtatacg
    71341 caatcaaagc attcgttaca ttataacttc caggcagcgg gatcgtaaat gtttctcctt
    71401 ctactacaaa atcggtttgt gcttttcctt ttgctgtcac ttccgcatga acatcgccat
    71461 ttccaatacc gaatgttgtg actgtttgta ctaatgttgc cgttaaaggt gtcagcaacg
    71521 gttcatctgc gggcacaacg agtaatccgt ctgatacaag tccgtcagtg atttccattt
    71581 tggctttagc gattccttct cgcgacccaa gattttctat gtgtgcttca ccgatcattg
    71641 tgattgctgc agcttttggt tgagccataa gtgaaagttc cgtgatttca ttggcgtgat
    71701 ccatgcccat ttccaaaacg atcttttctg tatcttgggg catgtgcaaa atcgtgtaag
    71761 gaagaccaat attattgttg taatttcctt gcgtcttata tgttttgtat ttttcagaca
    71821 agacagacgc ggttagatct ttcgtggtgg ttttaccatt gcttcctgta attgcaacga
    71881 cttctgcgcc tactttttcc aagtaatagg ttgccaattg ctgcatggct ttcaaaggat
    71941 ctgctacagg aataactgga aaattttttg gagcttgttc aacaggcaag ctccaaaatg
    72001 aagcagatgc tccgtttgtg atcgcttgct ggataaattc atgtccatct cgcgtaccag
    72061 caagaggaac gaataaactt ccttcggtta tcttccggct gtcaaattcg acattggtaa
    72121 tctttgtcag tgcagagcat tcgctgccca cggcttgtgc aatttcttgt attgttagat
    72181 tcattgagat ctctcctaaa aaaggttgtg aaaaaagcgt ttggcctaaa cggcgggttc
    72241 gcatgactct cacttccaag taaatttctc tattcgtatt tagaagctag aatgaacgcg
    72301 gttacgcaat cactccagcc tcttctttat ttctctttat tcattttttt caaaaaaaga
    72361 ttgacgctga tggtatcgat tcattcctaa ctggatcagt tcttcaatca aatcaccgta
    72421 tttcaagccc atattttccc ataagagtgg gtacatactg aactccgtaa atcctggcat
    72481 agagtttaat tcattcagga ataattcatt tttatttgtc aaaaagaaat cgcaccggct
    72541 caatccgctt ccacctaaca tcgtgtaagc taacttcgcg tactcttgcg ctttttgata
    72601 aacttcttct ggcacttcgg ctggaatctg catttcgatt ttattattga tatattttgc
    72661 ttcataatca tagaatgcta cgtcttttac gacttcacca ggcaaagtcg tccgaacgtc
    72721 ttcatttcct aatacagcaa cttcgatttc gcgcgcttca attccttgtt caacgattgc
    72781 tcgagaatca tactgatagg ctgttgctaa agcattttgc agctcttctc ggttttctgc
    72841 ttttgtaatg ccgacactag aacccatatt cgccggtttg acaaacatcg gataaagcaa
    72901 agaaccttca cattgatcaa atactttttt aggattttct ttccattgat tcttaagtac
    72961 tggtacataa ggaacttgcg gcacaccagc agcttgtaaa atatacttgg tcatgatttt
    73021 atccatggca catgcactgg tcaatacgcc tgcgccgaca taaggcatat tcaatgtctc
    73081 taagaagcct tggatcgttc catcttcccc gtttggccca tgtaaaactg gaaaaacgat
    73141 ggctccttct tctttgattt cgcccggatt gatcactttt cctgtaaagc cttcctctgt
    73201 ctgtccactt gggtcccatg aaagatgcaa gacatctttg ctggcaggtt tttctgttag
    73261 taatggacct ttgacccatt gtccttcttt tgtaataaat acgagttgaa cttggtaata
    73321 attataataa atggcattta aaactgaaaa tgcggaaaga atggacactt catgctctgc
    73381 gctgcgtccg ccatatagta aagtaatctt caaaagattg tcctcctgta ttctaaatcg
    73441 ttcagtgatt tactctcata ttttagcaca aaacaaaaat aaacgaataa cttatttata
    73501 aaaaaacgag ccagcttcta aaagaacgag cgtcatttat tttttgtcag ctagattatt
    73561 tgtcccgttt tttataaaaa gttatgataa agaaaaggag ggatgatgat ggcgcaaaca
    73621 aatccacgca gccgcttggc agaaatcatt cgagtgttca tcaattacaa tgtagtgcca
    73681 aactttgtac agcaaaaaaa tcccgaacag gtaaaaaaag cctttgaaga actaggcccc
    73741 accttcatca agataggaca gatgctttct gttcgagaag atttgctttc ttctgccttc
    73801 actcaaacat tcaaaacatt acaagatagt gtacctagcg acacattttc aacggtcaaa
    73861 aagacgatcg aaacagaact ttctctttca ttatcagata tattcgatga tttttcaaaa
    73921 tcgccttttg cctctgcttc tatggggcag gctcatcgtg ccaagctgaa gaacggtgac
    73981 gcggtagtcg ttaagatcca acaccctaac atcgccgaag agatccgact tgatcttcaa
    74041 ctatttgaac gagcgatccc tttgatcaaa tacattcctg aaactagcgt agttgatcta
    74101 aaaggggtac tccaagaagt aaaacgttcc ttgatcaatg aaatggactt cttaaaagaa
    74161 agtcaaaatg gcgaacaatt ctatcaaaag aacaatggct ggaaagagat ccgcagcccc
    74221 aagatttatg acgctttttg ttcgaaaaaa gtgatcgtga tggaagaaat gtctggtaaa
    74281 aacttgaatc atttaatgaa cgccgaaaac aaaactgaaa cttttatcac tggaattcaa
    74341 aacaagcagc tgaaacaaga agttgcaaag cttttagttg agaactttat gaaacaggtg
    74401 tttgatgatg gttttttcca tgctgatcct catccaggga atctgctatt ccatgtacta
    74461 acaaaagaag aacagacaca agctagccga aaaactgaaa cagtccatga aaaagagttc
    74521 ggttcctttg cttttcgagc ctccacttct gcagaagacc ctgttgcgcc atataccatc
    74581 aactacatcg attttggtat gatggggcat ctttctgcag gacttaggca aaaactcaca
    74641 caagccgttt tagcgctgta tacgaaagat gcttatcgaa tcgaaaaagc ggtccttcga
    74701 ctttgtcagc aagaaggctc gtttgatgaa agtcggttcc accaagaact gacaagtttt
    74761 cttgaacagt attatgattc tcctattgat gaaatcaact tgcaagaagt attcacacat
    74821 gtcgtgacga tttgtcatca aaataatctg cagttcgatc gtgatatcac gcttttgctg
    74881 aaagcatttg ggacattaga aggggtgatc cgcgtcctcg atcctgaagt ttccctcatg
    74941 gaagtcgctt cgccttttgc tcaacattat tttctcactc atctggatgt agaagataca
    75001 ttgaaacaaa gcggattaga cttattggaa gggatgaagg ctgcgcctaa gatccctcaa
    75061 cagctccacc atctattaga aatgtggact tcgggacaag gaaaagtcaa tttggaattg
    75121 aaaaagcaag acaaattatt gagcaggatc gaaagtatga tcaatcggct tgttttcggt
    75181 atgattttag ctgcattgat cgtagggtcc tccctgcttg tccaagcagc acctgtagaa
    75241 aacgcagagg tcgtttcctt attagggata tttacgtatg ctattgccgc attcgtcatt
    75301 atttttttgg caatcgatgc attgatccaa atgtataaga agaggaaaaa gtagaaaaag
    75361 gttgtgacag aaagaatcag cttcaagaaa taagaagggg ttttacataa attgtttctc
    75421 aaatttttgt gaaaattcgg cttatttttc gaagaggcta cttctgaaac accgagaata
    75481 aaaaatgtga aaaagctgtt ctgcacccag taataagaac aatcaaaaag ggaacatgga
    75541 acacatttat cctgtttccc tgttcccttt ttgatgtatt cgagcataaa taaaatacct
    75601 tcgttaccta ctatcttctg tacttggtaa accttagtca attgcctttt ttaacgcttg
    75661 acgaaaagac atatgatctt tctccgtaaa gggttttgga ccctttgtcc ttatgccagc
    75721 ttttcttaac tttccactat gataacgttg ttctagaagc gtgccgatat tcgcttcgtc
    75781 aaattctttt ccagagtgat ggaacactcg cacacccttc ggcaatacaa gtgaagctaa
    75841 accataatct tgcgtgatca aaaagtcatt cttcttaacc ataccgacga ttttataatc
    75901 cgcactatca gctccgcggt ctacgtagac gatttggaca tgattagcgt attctttggt
    75961 cgtataatgg tccacactgg tcacgataac cacgtcaaga ccataggatt ctcctaattt
    76021 tatgacatct tcttttactg gagaaccatc tccatcaatg aatagcctca ttctttttcg
    76081 ccttcttcca taaatgataa acagttacta atccgctcag taaaagacca acattgatcc
    76141 attttgccaa gataagcagt tgtacacttt ctatcggcac tgattcatgg ttcagcgtga
    76201 tcaataatag atggattggc tctcccattt cttttgctaa aacaaacaaa agcgtcatca
    76261 ataaaaactg gtggatcaca ctccctttat tttgagtagt atacttgaca acgatccggc
    76321 gatccattgg aatagctgta tcagtttgat aatattcctt atttagccag ctgcctgtta
    76381 ctacgtgcca gaaactaagc agaaagacac ctatcgcaaa accatttgga atcaagagga
    76441 ccaataaaga agaactcagt ccaagcaatt gcatagccaa tggagaccat gttaaacgtt
    76501 tcaaaatcca tggtccgact atttttgctg caatcaagcc tgctgcataa ggcaaataca
    76561 taaaaatcga aagtttttct aatccgtaca gtatgccaac ataaaaactg ctaaataaaa
    76621 aaaggaaatt ccctagcatt ccatttagaa aagtaaacag atttagccag cttggcaact
    76681 tccattcctt cttctggtgt cctaaaacaa acacgaacaa gatgaacagc agcaagaaac
    76741 cataaatagc aagatcaaaa agcctttcat cgaataacaa tcgggcattt ctcaaaagaa
    76801 acaataagcc aaagaatatc aaaaataaaa caagctctcg cgtagctacc agatttcttt
    76861 tgatgtcttt gaaatccagt tcgtaacgcg gataatgact aaccgtatgg taggccatga
    76921 cgtaaaaaag tgtataaata gtaaagcttg ctgcaatctg agtcggtgca ggcaactcaa
    76981 tcgcttgata caggagaaat agccagatag ctgcaaataa gtactttttc ccatccatat
    77041 tgataaaacc ttgcgtcttt tcgtgaaaat tgaccgtggt attagcaggt acaagccatg
    77101 ctgcactcag ccctagcaaa acacttgaaa aataaaataa aggaaaataa aatacgccta
    77161 atattccaag caatgaacca gcaccaccaa tcagcagagc gatcatcagc aacgtgtaac
    77221 tatctagacc aaatcgtaga ctgttgacta aaaatagtcc agtcatccga aaggcataaa
    77281 acagcgtaaa tggcaaaatc gtcagccaat tatgcgagtc tgttagtccc aaaaataaaa
    77341 gataaggaat aaaaataacc gtgttactta agataaaggg cgttgtttgt gtaaaattac
    77401 gcccaaatcg tttgagtttt tcgaacatga caatggctcc ttaaacagtc ttataactaa
    77461 tctgctcttc gattttagca ttaaagggga aataaaccaa ttttacagaa tatattcttg
    77521 taaaaaaaaa tacagaaaga agcataagct tctttctgca tttttacggt acttgattac
    77581 tcaagcagac aagcccttct ccacaaaagt cttgcccgac acccctgcat ccggcaggtg
    77641 ataaagatag aaatcaatta tcctgtgcct ccaaaatcaa ttaggagctc tgtaaaccag
    77701 agtccttctc gacccgtcgc ataaatttac tttaacacag ttcctatgtt tatgcgagag
    77761 cttttttcat tttataatcg accatttgaa atccttgacc gatatctgaa ataagttctt
    77821 ctgtaatctc aaatccttca tgcttataaa cctcgattgc ttgatgattc ccctgattca
    77881 ctcgcaaaaa gatctctctt tcctttgttt gcgcagcaag ttcttcatac cagcgaaaaa
    77941 ctgaagaagt caatccttga ccacgtactt tatttagcaa atataattta cttaaataaa
    78001 tttttccatt tatctcttca taagcagtgt aaccgacagt cttttcttcg ctttttaata
    78061 aaaagtagga cacaccttct gtcagttctt tttgaatctg tttttttgac tgataagttt
    78121 tcagcatgta atccacttgt ttttgaccaa tgatcggcac aaaaacttcc ggccatactt
    78181 cttgtatgac tgccatcagc tcatccagtt cattttctgt tacttttatt ttttccatac
    78241 acccacgtcc ttttttacat tataaatgac cttgcgcttg atggaataaa aagagcatga
    78301 tcatgctata cacacccacc gaccacggtt tcaagaaaat cacaatctgc ataaattccc
    78361 taaaagataa tttcgtcaaa ccagctacta gacagatcaa gtcgtctggc gcaaagggaa
    78421 gcagcaaggt aacaactagt acttttttaa tatctttcgt ttttcttgtc agcaattcat
    78481 caaatttctg atactttttt ggcgataaaa taagctggac aaaggctacg ccatagtaac
    78541 ggacaagcaa aaatccgatt gcttccccaa tcactaggcc aatacaacta tataaaagcc
    78601 caaatccatt gccaaacatc agcatgcccg ctactgagga gatccctccc ggcaaaatag
    78661 gaatgatcac ttggatcact tgcaacagaa caaatatcat cactgcatac ttgccaaatt
    78721 gctggataaa cgcttgcaaa gacgtgctcg atcgaaaaat cccatgatga taagcataaa
    78781 gaatcaacac aaagaaaaaa aacagaccaa taatgggcat gatctgaaga catttttgta
    78841 aaactgatcc ttttttagac atctatattc cccacatctt ttttcattta ttaaaactgc
    78901 ctcctt
//
LOCUS       DADLIO010000006        62070 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.006, whole genome shotgun sequence.
ACCESSION   DADLIO010000006 DADLIO010000000
VERSION     DADLIO010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 62070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62070
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.006"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(224..709)
                     /locus_tag="JOX41_000508"
     CDS             complement(224..709)
                     /locus_tag="JOX41_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HAY6448275.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     gene            1189..1830
                     /locus_tag="JOX41_000509"
     CDS             1189..1830
                     /locus_tag="JOX41_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAY6448276.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIIMKQVEGKLNYYR"
     gene            1849..2484
                     /locus_tag="JOX41_000510"
     CDS             1849..2484
                     /locus_tag="JOX41_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAY6448277.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            2502..3317
                     /locus_tag="JOX41_000511"
     CDS             2502..3317
                     /locus_tag="JOX41_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HAY6448278.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            3636..5072
                     /locus_tag="JOX41_000512"
     CDS             3636..5072
                     /locus_tag="JOX41_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAY6448279.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            5261..7708
                     /locus_tag="JOX41_000513"
     CDS             5261..7708
                     /locus_tag="JOX41_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HAY6448280.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            7938..9005
                     /gene="rlmN"
                     /locus_tag="JOX41_000514"
     CDS             7938..9005
                     /gene="rlmN"
                     /locus_tag="JOX41_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HAY6448281.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(9198..10301)
                     /locus_tag="JOX41_000515"
     CDS             complement(9198..10301)
                     /locus_tag="JOX41_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAY6448282.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            10854..11402
                     /gene="aac(6')"
                     /locus_tag="JOX41_000516"
     CDS             10854..11402
                     /gene="aac(6')"
                     /locus_tag="JOX41_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HAY6448283.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            11948..13609
                     /locus_tag="JOX41_000517"
     CDS             11948..13609
                     /locus_tag="JOX41_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HAY6448284.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(13679..14026)
                     /locus_tag="JOX41_000518"
     CDS             complement(13679..14026)
                     /locus_tag="JOX41_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HAY6448285.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            14110..15051
                     /locus_tag="JOX41_000519"
     CDS             14110..15051
                     /locus_tag="JOX41_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAY6448286.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            15052..16095
                     /locus_tag="JOX41_000520"
     CDS             15052..16095
                     /locus_tag="JOX41_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAY6448287.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            16101..17171
                     /locus_tag="JOX41_000521"
     CDS             16101..17171
                     /locus_tag="JOX41_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6448288.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            17161..18114
                     /locus_tag="JOX41_000522"
     CDS             17161..18114
                     /locus_tag="JOX41_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAY6448289.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            18126..19136
                     /locus_tag="JOX41_000523"
     CDS             18126..19136
                     /locus_tag="JOX41_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAY6448290.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(19421..20242)
                     /locus_tag="JOX41_000524"
     CDS             complement(19421..20242)
                     /locus_tag="JOX41_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HAY6448291.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(20339..20617)
                     /locus_tag="JOX41_000525"
     CDS             complement(20339..20617)
                     /locus_tag="JOX41_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448292.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            20885..22894
                     /gene="metG"
                     /locus_tag="JOX41_000526"
     CDS             20885..22894
                     /gene="metG"
                     /locus_tag="JOX41_000526"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HAY6448293.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(23373..23960)
                     /locus_tag="JOX41_000527"
     CDS             complement(23373..23960)
                     /locus_tag="JOX41_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448294.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            24135..25457
                     /locus_tag="JOX41_000528"
     CDS             24135..25457
                     /locus_tag="JOX41_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAY6448295.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            25612..26388
                     /locus_tag="JOX41_000529"
     CDS             25612..26388
                     /locus_tag="JOX41_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HAY6448296.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            26381..26950
                     /gene="rnmV"
                     /locus_tag="JOX41_000530"
     CDS             26381..26950
                     /gene="rnmV"
                     /locus_tag="JOX41_000530"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HAY6448297.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            26943..27827
                     /gene="rsmA"
                     /locus_tag="JOX41_000531"
     CDS             26943..27827
                     /gene="rsmA"
                     /locus_tag="JOX41_000531"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HAY6448298.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            28278..28907
                     /locus_tag="JOX41_000532"
     CDS             28278..28907
                     /locus_tag="JOX41_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448299.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(29031..30140)
                     /gene="ugpC"
                     /locus_tag="JOX41_000533"
     CDS             complement(29031..30140)
                     /gene="ugpC"
                     /locus_tag="JOX41_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HAY6448300.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            30349..30771
                     /gene="mgsA"
                     /locus_tag="JOX41_000534"
     CDS             30349..30771
                     /gene="mgsA"
                     /locus_tag="JOX41_000534"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HAY6448301.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            31094..31630
                     /locus_tag="JOX41_000535"
     CDS             31094..31630
                     /locus_tag="JOX41_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAY6448302.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(31670..33433)
                     /locus_tag="JOX41_000536"
     CDS             complement(31670..33433)
                     /locus_tag="JOX41_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6448303.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(33436..35151)
                     /locus_tag="JOX41_000537"
     CDS             complement(33436..35151)
                     /locus_tag="JOX41_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6448304.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(35930..36154)
                     /locus_tag="JOX41_000538"
     CDS             complement(35930..36154)
                     /locus_tag="JOX41_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448305.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            36354..39122
                     /locus_tag="JOX41_000539"
     CDS             36354..39122
                     /locus_tag="JOX41_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAY6448306.1"
                     /translation="MLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNTVSH
                     YLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQPKDL
                     FSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLHDLL
                     EDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLDEVH
                     RLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRIPIR
                     IELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGELKNI
                     VKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLMEKQ
                     QPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHELLVY
                     WTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELEQQV
                     SQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIAAHG
                     YATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILVDMG
                     SLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPEWRL
                     LYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNSDPL
                     FSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQRII
                     RNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLIERL
                     IRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSEDTE
                     FLSIEEEF"
     gene            39203..39622
                     /locus_tag="JOX41_000540"
     CDS             39203..39622
                     /locus_tag="JOX41_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HAY6448307.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            39634..40104
                     /locus_tag="JOX41_000541"
     CDS             39634..40104
                     /locus_tag="JOX41_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAY6448308.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            40121..40900
                     /locus_tag="JOX41_000542"
     CDS             40121..40900
                     /locus_tag="JOX41_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAY6448309.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            40887..41708
                     /locus_tag="JOX41_000543"
     CDS             40887..41708
                     /locus_tag="JOX41_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAY6448310.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            41725..42774
                     /locus_tag="JOX41_000544"
     CDS             41725..42774
                     /locus_tag="JOX41_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAY6448311.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            42787..43791
                     /locus_tag="JOX41_000545"
     CDS             42787..43791
                     /locus_tag="JOX41_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAY6448312.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            44424..45443
                     /locus_tag="JOX41_000546"
     CDS             44424..45443
                     /locus_tag="JOX41_000546"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HAY6448313.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            45486..46367
                     /gene="galU"
                     /locus_tag="JOX41_000547"
     CDS             45486..46367
                     /gene="galU"
                     /locus_tag="JOX41_000547"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAY6448314.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            46667..47044
                     /locus_tag="JOX41_000548"
     CDS             46667..47044
                     /locus_tag="JOX41_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448315.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            47650..48264
                     /locus_tag="JOX41_000549"
     CDS             47650..48264
                     /locus_tag="JOX41_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAY6448316.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            49037..50776
                     /gene="yfcC"
                     /locus_tag="JOX41_000550"
     CDS             49037..50776
                     /gene="yfcC"
                     /locus_tag="JOX41_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HAY6448317.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            50933..52117
                     /gene="iadA"
                     /locus_tag="JOX41_000551"
     CDS             50933..52117
                     /gene="iadA"
                     /locus_tag="JOX41_000551"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HAY6448318.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            52228..52431
                     /locus_tag="JOX41_000552"
     CDS             52228..52431
                     /locus_tag="JOX41_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HAY6448319.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(52532..53194)
                     /locus_tag="JOX41_000553"
     CDS             complement(52532..53194)
                     /locus_tag="JOX41_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6448320.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(53207..54709)
                     /locus_tag="JOX41_000554"
     CDS             complement(53207..54709)
                     /locus_tag="JOX41_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAY6448321.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESRETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            55257..56936
                     /locus_tag="JOX41_000555"
     CDS             55257..56936
                     /locus_tag="JOX41_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HAY6448322.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            57063..57542
                     /locus_tag="JOX41_000556"
     CDS             57063..57542
                     /locus_tag="JOX41_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HAY6448323.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            57761..58441
                     /locus_tag="JOX41_000557"
     CDS             57761..58441
                     /locus_tag="JOX41_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HAY6448324.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            58449..59780
                     /locus_tag="JOX41_000558"
     CDS             58449..59780
                     /locus_tag="JOX41_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAY6448325.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            59795..60757
                     /locus_tag="JOX41_000559"
     CDS             59795..60757
                     /locus_tag="JOX41_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HAY6448326.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            60868..61206
                     /locus_tag="JOX41_000560"
     CDS             60868..61206
                     /locus_tag="JOX41_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HAY6448327.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            61285..61992
                     /locus_tag="JOX41_000561"
     CDS             61285..61992
                     /locus_tag="JOX41_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HAY6448328.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
BASE COUNT        20289 a        10789 c        12994 g        17998 t
ORIGIN      
        1 aattccgatt tataatcgaa aaaagaagca tttttatata tgcttctttt ttcgtagaat
       61 caataaatat ggatttggct aactatggaa gaatactcgt attagttttc agcgttcata
      121 ctagttgtta cattgtttga ttggccaaaa gaatttctga tatattttgt gctaaataaa
      181 gaaaaagacg cttgaattgg gaaataagaa aactactcta tcattacaaa ttttcataaa
      241 ctggcagatg ttctaagtaa acaagtatct tttcaaagtc ggaaaaatcc ataatcaacg
      301 tagtggtatt gatatttgga tgaaagccta cggtatcttg acgatcaata gcagcatcga
      361 tcacgacttg gatttttttc tctttgtcgt gcatcaatgc taatggagtc actgtacctg
      421 ctggaacgcc taggaggtca ggaagctgtt cttcagaaac aaaagataag cgcttttctt
      481 ttaattgttc agctagttgt tttaaatcgg cgtgcttttc atcaggcaag atgacaagat
      541 agatttgttt tccttttctt gatttcaata atagattttt tacttgcgga ccaggtaggg
      601 aaaaagggac atttttgact gacgtaatcg caggatgatc gactttttga aaagagatac
      661 ccagtttttt tagtagttca taagcttctt gttcggttgc acgactcatc gcgcatcacc
      721 ctcctttttt tattagtgta tcataaaaaa gagttgacaa atgaaaaata atcatgtaaa
      781 ttacacgtaa agttaaaaca aatgacatcg aaaagaagag tagccgttag gtgtttttag
      841 agagtctctg gttggtggaa agaggcagca gttaaccgtg aaacacatct tggagtcgat
      901 tttctgaagc gtatagtagg aaaatccggg gagcccgtta cagctgcggt cgttgctaga
      961 tgaccagata aggctggctt ttccgtgagg agtcggtaaa aaaaggtgga accacgtgat
     1021 taacgtcctt tgatcttcgg atcaaaggac tttttgtttt catctgaacg gcaacgactg
     1081 tgtgaggttt tttctgcaag gaaaaaataa acagaggtgg aaccacgtat aatacgtcct
     1141 cttggcattt gccaagagga tttttttatt ttaaaggagg aaaagaagat ggagtatttg
     1201 attgaagtta tgccgcaatt attagtagga gcactcacaa cattgaaatt atttttattt
     1261 accttgattg gctcattacc attagggatt gttttagcat taggattgtc tttgcatttt
     1321 aagccgctac gctacttgct tcaaacatat gtatgggtta tgcggggaac accgctgttg
     1381 ttgcaactga tttttatttt ttatgggttg ccgacgattg ggatcgtttt tgatcgtttc
     1441 gaagcagcac tcattgcctt tatcttaaac tatgcagctt attttgcaga gatctttcgt
     1501 ggagggatac aatcgattcc tcaaggtcaa tatgaagcag cgcaagtttt gcaattaagt
     1561 ccctttcaaa cggtgacgaa aatcgtcatc ccacaagtga caaagattgt tttaccttct
     1621 gtagggaatg aagttatcaa cttggtcaaa gattcttcct tgatctatat attaggttta
     1681 ggtgacgtaa tgcgtgctgg gaaaatcgcg atggaacgcg acgcgacttt actgcctttg
     1741 ctaggcgtgg caatcatcta tcttacattg actggtattc taacaatcat aatgaaacaa
     1801 gttgaaggaa aattaaatta ttaccgctaa ctgataggag gaagaaatat gattgaattg
     1861 aagaaagtga acaaagcatt tggtgaaaaa aaaataatca aagatttgaa tctaatcatt
     1921 ccagatggga aaacattagc tatcgtaggt ccttccggtg gcggtaaaac cacgctttta
     1981 cgtatcttgg ctggcttaga aagttctgac agcggagaat tttatttaga cggtgtaccg
     2041 ttcaacccat tcgagcttaa aatgaaagaa caagttgtag gagtcgtatt ccaagacttc
     2101 cagctatttc cacatctgaa tatttttgaa aacattacct tagcaccaaa aatggtattg
     2161 aaacagacaa aagaagaata caccaaaaaa gcagaagaat tagcggcttc attagggatt
     2221 agtgatttat tgaatatcta tccttatcag ctttctggcg gacaaaaaca gcgggtagct
     2281 attgccagag cattggctat gaatccacgg gtattggctt atgatgaacc aacaagtgct
     2341 ttagatcctg aattacgcca gcaagtcgag cgtttgatcc tatcattgaa agaagatggg
     2401 gtaacccaaa ttattgtcac ccatgattta gtatttgcag aaaatgtcgg tgatcaatta
     2461 ctaaaagttt ccccaattca ttaagaaagg agaagataga gatgaaaaaa accagttttc
     2521 tattcgcttt gatcgcaggt cttcttcttt ttgcaggctg ttcgaacaaa aaaacttcag
     2581 cagataattg ggcgactatc aacgaagaga aaaaaatcgt tataggttta gacgatacat
     2641 ttgttcctat gggatttaga gataaagacg ggaagctcac aggatttgat attgatttag
     2701 ccaaagcagt ctttgaacaa tatgggatta cggtagactt tcagcccatt gactggtcaa
     2761 tgaaggaatt tgaactgaac aatggaacga tcgatttgat atggaacggc tattccaaaa
     2821 cgccggcaag agaaaagaaa gtgcaattta caaaacctta tatggaaaac gatcaagtgc
     2881 tgatcacacc taaagaatca ggaatcacaa actttggaca aatgaataat aagagattag
     2941 gtgcgcaaaa tgggtcatct ggttatgatg tatttacgaa acaaccagaa gtattaaaag
     3001 agatagtcaa aaaccaagat gctgttttgt atgatagttt taatgaagca ttgatcgatc
     3061 tgaaaagcag acgggtcgat ggtctgctga tggataaagt atacgcagac tattatttga
     3121 aacaaagaaa cgaactagaa gacttcaaca taacaaaagg ttcttatgag agtgaggatt
     3181 ttgcagttgg tgcacgcaag tcagatagta cattagtgaa aaaaatcaat gaagccctag
     3241 atcaactaga gaaaacaggt gaattccaaa aaatatccga taaatggttt ggcgaagatg
     3301 ttacgccgag aaattaacaa ataggggact gtgacaaaag acgtgtcaca gtcccttttt
     3361 ccgaataaac agtgttctcc tgccaactcc ttgtgactcg gagctgaatg gcaggctcac
     3421 aacctcttgg taaacggtgt tcaaaagcca gtttttcggt attaagccaa atttatgcaa
     3481 aaatgtagaa agccattttc acaaaatttt tcttactact cgaaactaag cgactttttc
     3541 acaacctcct ttacataatt ttattttgtt gtggaagggg tttcgtgtta ttctaaaaga
     3601 ggaacgattg aaggttatag gaaaggaaga gatgaatgga acacaaagaa cttacctcat
     3661 ttccaaaaga ttttctgtgg ggctctgctt ctgcagcgta tcaagtagaa ggagcttggc
     3721 aagaagatgg gaaaggagaa tcagtctggg atcgatttgt acggatacct ggaaagacat
     3781 ttaaaggaac gaacggtgat ttggcagtag accactatca tcgttataaa gaagatattg
     3841 ctttaatgaa agaacaaggt ctgaaagctt accgcttctc tgtagcttgg acacggattt
     3901 ttcctaatgg acgaggagaa gtcaatcaag ctgggctcgc tttttatgag agattgatcg
     3961 acgaattgat tgaaaacgat attgaaccta tgttgacttt atatcattgg gatcttccac
     4021 aagcattgca agatgaatat aatggttggg aatcacgtca gatcattgaa gatttcactc
     4081 attatgcaga aacattattt gaggcattcc gcgggaaagt ccattactgg attagtttga
     4141 atgaacaaaa tatcttcact tcattaggtt atttgttagc agcacatccg ccaggtgtga
     4201 cagacccgaa acgaatgtat gaagttaacc atattgctaa tttagcaaat gcatctgtca
     4261 tcaataaatt tcacgagtta gaaatgcctg gaaaaatcgg accaagcttt gcgtatacgc
     4321 caaattatcc aattgacagt aatcctgaaa atgttctggc tgctgaaaat gcagaagacc
     4381 tgatggccaa ttattggatg gatgtctata tgtggggaaa atatccgatt gctgccatga
     4441 ggttcttaga agaaaaagga tgggcaccaa cgattgaagc tggcgatgca gaattgctag
     4501 aatctgctaa accagatttt cttgggatca attactatca aacggcgacg aatgcattca
     4561 atccattaaa cggagttggt gctggaaaaa tgaatacgac aggaaaaaaa ggttcatcag
     4621 aagaaactgg agttcctgga atgtataaaa aagttgagaa tccatttgtc gaacgaacaa
     4681 attgggactg ggagattgac ccagaaggat taaggatcgg actgcgtcgt atcacaagcc
     4741 gttaccgcat gccggtactg attacggaaa atggcttagg agagtatgac aagttgacag
     4801 aagataaaca aatccatgac gactatcgaa tcaattactt acaaagccac gtcaaagcca
     4861 tcaaagaagc aatttcggat ggagcagaag tcctaggcta ttgcacctgg tcttatacag
     4921 atttgcttag ctggctgaac ggttatcaaa agcgatatgg atttgtatat gttgatcaag
     4981 acgaaacaca agaaggatct ttggaacgat ataagaaaga cagttattac tggtaccaaa
     5041 aactgattga agaaaatgga gagaaccttt agttcacata cttaaaacaa gaaggtacgg
     5101 ctggatatgg ccgtgccttt tcttgataaa atcatttaga aattaagaaa aactgtaaaa
     5161 taagctgaaa aatgaaagaa agcgtcagtt ctttcaaaca aaactttagt tcccttactt
     5221 ttttttgtat aatgaaactt gatgaaatga gggataataa atggcacaaa agaaacggcc
     5281 tactaaaaaa aggaaaaaga cgaaaaaaac gaaaaagcaa aaacagcagc aggaacaaat
     5341 gctgacgatt ggtgttgggt ttgccttgat tttatttgct gtcttcggct ttttaaaatt
     5401 aggtttttta ggaatattga ttgcaaacgg ctttcggatc attgcaggaa atacttacca
     5461 aatcctctgt cttttattag ccgtattagg attttggatt gtcattaaga atacagagtt
     5521 ttcaattggt aaaaaccgac gctggtttgg cggcatactc ttttatttcg gtatcttatt
     5581 attgttacat gcccatttat ttggcaaact ccatactggg gaaccaaata tcatggggac
     5641 gacatgggat ttgttagcca gtgatataaa acaaagtcaa gtagacaata acgttggtgg
     5701 tgggatgatt ggagcaatcc tttatcattt tacttacttc ttgattgcac agcctggaag
     5761 ttatttagca gcagtgctat tactggcagg aggagcattc ctgttcagta atctggaagg
     5821 ctatcagctg ttaaatggta tccaatcaat tggagaacga gtacaggaat tattggaagg
     5881 tgatcctgcc aagcaagctc gaaagcaagc ggcaaaggaa gagagaatga aacagcgcgc
     5941 agaagcgaaa gaagcaaggc gcttagctgc aaaagaagct gcagaaaaag aagctgcaga
     6001 atatgagaag aaaaaagcgg tgagccagca aagggaaaat actgctgatg aatggcagga
     6061 accagaaaat acagagccgg agcagctaag ttttgttcca atcgacagtt ttcaagaaaa
     6121 tatccatcct gcgaatctag agaaaccagt accagataca ccaaaacaga ccaatacagc
     6181 agaaggtttt tcagatgagt tgccagagga tgacggtacc tcattagaat ttgagattga
     6241 agcagaacag gaaaatcaag actatgaatt accgacagtt gatttgcttg attctatacc
     6301 aactgtggat caaagtgatg agtataaaaa aattgaaaaa aatatcggcg tattagaaca
     6361 aactttccaa agtttcggtg tcgatgccaa ggtcgtcaaa gccagcttag gaccatccgt
     6421 cacaaaattc gaagtccagc cggctgtagg ggtaaaagta agtaaaattg tgaacttaac
     6481 agatgatatc gcgcttgctt tagcggcgaa agatgtccgg atggaagcac cgattccagg
     6541 taaatcactg attggtattg aagtaccaaa tggaaagatc agtatggttt cctttagaga
     6601 aatcatcgaa gcacaaccaa accacccaga taaattacta gaagtacctt taggacgtga
     6661 tgtttctgga cgggtacaaa cggctgatct ttcgaagatg cctcacttac tcgtggctgg
     6721 ttcgactggt agtgggaagt cagtagcaat taatgggatt atcacaagta tattaatgcg
     6781 tgctaagccc catgaagtaa aactgatgat gatcgatccg aaaatggttg aattgaatat
     6841 gtacaacggc atacctcatc tgttgacgcc ggtcgtgacg aaccctagaa aagcagcgca
     6901 agccttacaa aaagtagtac aagaaatgga agaacgatat gaaaaattcg cggcaaccgg
     6961 agtaagaaat atttctggtt acaatgaatt tgttcaacag aaaaacttgg aaaacggaac
     7021 gaaacatcca accttaccat tcatcgtagt gatcgtagat gaattagctg atttgatgat
     7081 ggtagccagc aatgaagttg aagatgcgat tattcgttta gcgcaaatgg ctcgggcagc
     7141 ggggattcat atgatcctag ctactcaacg tccaagtgtg gatgttatca caggaatcat
     7201 caaagcaaat gtaccttcca gaatggcatt tgcggtatca agcggtacag attctcggac
     7261 gatcattgat tctaatgggg cagaaaagct cttagggcga ggagatatgc tattcttgcc
     7321 aatgggtgag aataaaccga tccgtgtgca aggagcattc atttctgacc acgaagtaga
     7381 acgggtcgtt caatttgtta cagatcagca agaagctcat tatgaagaga aaatgatgcc
     7441 gacagatgaa gttgaaacga caggtgctcc agaacagcca caagatgagc tgtttgaaga
     7501 agcaaaagca cttgtcgttg aaatgcaaac ggcaagtatt tcccttctcc aaagaagatt
     7561 tcggatcggt tacaaccgag cagcacgttt agtagatgaa ctggaagctc atggagttgt
     7621 tggcccgtca gaaggaagca agcctcggaa agtattcatt gagcaggaag aaacatcaga
     7681 aacgttgccg gacgataatg acatgtaaaa cttgtgtgat gaagggttga aaaacgaata
     7741 accaataaaa agacaaggca tgatgatacc aaaagaaaaa atggtttttt tccatctttt
     7801 ctaatacggt atgatgtctt gtctttttag tttttgtgag attaaagttc tattcgattt
     7861 atttgtgaag tattgcatta aggaaatgaa tcatgtatag tatgtagcga aactttgaga
     7921 aaaagaggga aaatactttg gaaaaacagt ccatttatgg cttgacgaat gaagaattaa
     7981 tcaattggtt tatagaaaac ggcgagaaaa aattccgagc tgcccaagtt tgggaatggt
     8041 tgtatcaaaa acgtgtaagt aatttcacag aaatgacgaa tctatcgaaa caattgatcg
     8101 aaaaattatc ggagcatttt atcatcaatc ctctaaaaca gatggtcgtc caagaagctt
     8161 cggatggtac agtaaaatat ttgtttgaac tccctgataa aaacatgatt gagactgtac
     8221 tgatgagaca agaatatggc ttgtcagttt gtgtgacgac acaagtagga tgtaatatcg
     8281 gctgtacgtt ttgtgcaagc gggctgctca aaaagaaccg tgatctgact gctggagaaa
     8341 ttgttgcaca gatcatgatg gtccaacatt attttgatga gcgcaatctt ggcgaacgcg
     8401 tttcacatgt cgttgtaatg gggatcggtg agccatttga taattacgac aatgtaatgg
     8461 actttttgca tatcatcaat gatgccaaag gattggcaat tggtgctcgg cacattacag
     8521 tttccactag tggattagca cacaaaatca aggaattcgc taataacggc ttgcaagtca
     8581 atctggctat ttccttgcac gcgccgaata atgaggtgcg aacatcgatc atgcggatca
     8641 accgaagttt cccaattgag aaattgatgg aagctgtgga tgagtattta gagaaaacaa
     8701 accgtcgaat cacgtttgaa tatatcatgt tgaatcaagt aaatgataga ccagagcatg
     8761 cgcaacaatt agcagatcta ttaaaagata agaaaaaatt agcatatgtc aacttgattc
     8821 catataatcc agtcagtgaa catgatcaat attctcgcag tccaaaagct gatgtattga
     8881 gattttatga tgtattgaag aaaaacggcg taaactgtgt gatacgtaaa gaacatggta
     8941 cagatattga tgcagcttgc ggacaattgc gaagcaagca aatgaaaaaa acagttgcca
     9001 aataatcgta tcctactcgt tttttcaatt accataaaag gagcagtttt cttaattaag
     9061 gaactgttca acttaaataa gagaaaagat tctatagcga aagctataaa gctttttttg
     9121 acaagaaaaa ccctcatcaa gcaaagaaat gtcctcaatt tgatgacagc ctgcttgatg
     9181 ggggttttag caattattta actgattttc ttatatcctt gctggctttc ttgtgtagca
     9241 tgataagttt ctacgtcaag aatggcctgt ttaaattttt ctcgggtgat ttcataaggc
     9301 acatgtttaa tatcatttgt tgccatggct ttatctaaga ttgcttctaa atcggtcgtg
     9361 acattgagat tcatgtcggt taacgatact ggaagttggt tctttttcat aaacacatag
     9421 attttatcaa acaaatcgaa ctgctgatcc atcatcaata aggtcagtac accataactg
     9481 acagatgctc cgtgaaggta tccctccatt ttttctagaa cagtcgtacc gtaatagaat
     9541 gagtgtgcca tagcagaatt atagttattg ttaactaaaa cagaaaccaa tccggtagta
     9601 acaatgatat ccgaaacgac ttgttcaatt gcatatgagg gacgatcgtc ggcactatct
     9661 ttcaatgctt gcgtaccata agtcaagaga cgatcaatgc acatttttcc gatttggatt
     9721 cctaatctat ccgtgtagcc tagatcatcg ccacgagcag aaaaagtaga ttcgacttct
     9781 ttggataaag catcgccaat acctgcccat aagtatttat caggtgcttc ggcaataatt
     9841 gctgtatcaa tgaaggtgtg tacaggtggt tttgaaggaa agaagagtcc gtccattacg
     9901 ccttcttcgt tatagatgac acataccgca gtgacgggcg aacagttcga accaatagtg
     9961 ggaaaggtga agactggttt agctagtttt tcaccaatga cttttacagt atcgcaagca
    10021 cggccaccac cgactgcaaa caggacgtct gctttttgga cactttcatg ctggatcaac
    10081 tgttcaatat ttccataagt tgaattaccc ccgtaccaga gactggcgac aacctctatt
    10141 tcctgtgtca aagctacttt tattttgttt tctgcctttg aaagtgcagt cttccctcca
    10201 atcagcacta cttttgtccc atattctttg acgattccat ttgctttttc atacgcatct
    10261 gttccaatgg tataatttgg taagaaaaca ctttgactca tattcatttc cttctttctt
    10321 cgttgaaacg ggttaaaatt ttaaagagtg atcgatctga ctgcggctgt agatggagta
    10381 gaggtgaacc taagacagga taagtgatga ataaggtggc atgaacacct tgaaatcatc
    10441 aataagtatc ctaaaaacga acaagtacaa aaacattgaa aacgacaata atgaattttt
    10501 gttcctctta gtatttctac cgattccctt tgcttttttg taattatcta aaaattctaa
    10561 aaattaagat tattatatga aaacaggttt tatttgtcaa ttcataattg gtttttttta
    10621 aagcaaaaga taatctatat catgatgaac aaacagagtt ttttcctcca attgatggct
    10681 ttcctgatct ttcctatttt gaataaagtg tttctgtata atttttttat tttataagta
    10741 agataaataa tgaaagaata gagatactga ttggtagcta aagatttttg agcgagaaca
    10801 tttcgttttt tcaaaaggac tgttagaata agcaagaaca agggggaaga cgtatgataa
    10861 tcagtgaatt tgaccgtaat aatccagtat tgaaagatca gctttctgat ttactgagac
    10921 tgacttggcc ggaagaatat ggagacagct cggcagaaga agtagaagaa atgatgaatc
    10981 cagaacgaat cgcggtagca gcggtagacc aagatgagtt agtaggattt attggtgcaa
    11041 tccctcaata cggtatcaca ggttgggaat tgcatccatt agttgtagaa agctcccgac
    11101 gaaagaacca aataggtact cgattagtca attacttaga aaaagaagta gcttccagag
    11161 gaggaatcac gatttattta ggtacggatg atttagacca tggaacaacg ttaagtcaaa
    11221 cggacctgta tgagcataca tttgataaag tggcttccat ccagaacctt cgtgaacatc
    11281 cgtatgaatt ctatgaaaaa ttaggttata aaatcgtagg tgtcttacca aatgcaaatg
    11341 gctgggacaa accggatatt tggatggcaa aaacgattat tcctcgacca aattctcaat
    11401 aataaaaaga ggttgtgaca gaagtaatca gcttcaagaa ataagaagga atttacgaaa
    11461 attacttctt gaatttttgt gaaattccaa cttatttccg aagaagctac ttttggaaca
    11521 ccgtgtacca gaggttgtga aaaagtcgct tagtttcgag tagtaagaaa aattttgtga
    11581 aaatggcttt ctacattttt gcataaattt ggcttaatac cgagaaactg gcttttgaac
    11641 accgtttatt cagataaggg actgtgacaa gacttttgtc acagtttctt tttgtttatt
    11701 cttttttatc tttgtatggc aataatagac aatataacga aaattattta atggcttttg
    11761 gaagaccatg gaaaaccttg tacaaagcta ttttttctga aaaattcctt gaaacctcac
    11821 gaaaaaatca ttattttatg aaaaagacaa aaaaaagtgt tgatttttta ataattattc
    11881 attaaactct taaacaactt cagaaaatat taattattct gaaaattcca ataaaggggt
    11941 acgtaaaatg aaaaagaaat ttacatttgg tttggttgcg gtatgcggcc ttgtacttgc
    12001 tggatgttat ggcggcagtt cagccacaag cagtagttca gcaaaaagcg gttcagcaga
    12061 tggaggaggc gtatttaact tagtcgtgcc tcaagaaatg cctacagctg acttatcagt
    12121 tgcaacagat acaatcagtt ttacagcatt gaataacgtt tatgaaggaa tttaccgtct
    12181 tgatgaagac agcaaaccac agccggcagg agctagcgag ttggcagaag tcagtgaaga
    12241 cggattaact tacaaaatca aattacgaga agacgcaaaa tggtcaaatg gtgatcctgt
    12301 tacagcagcg gattacgttt atggctggca acgaacagta gacccagcta cagcttctga
    12361 atatgcttac ctgtatgcgc cagttgaaaa tgcagaagac attacagctg gaaagaaaga
    12421 taaatcagaa ctagggatca aagcagttgg tgactatgaa ttagaaatca aattgacgaa
    12481 acaaacacca tatttccaat atctgcttgc tttcccatca tttttcccac aaaaacaatc
    12541 cgtagtggaa gaaaatgggg atgcctatgc atctgcaagt gataaagctg tttataatgg
    12601 accattcaca ttagaagatt ttgatggacc aggaacagat acagaatgga cttataagaa
    12661 aaatgatcat tactgggaca aagatacagt aaaactttct gaaatcaaag tcagtgtagt
    12721 aaaagaatct tctactgcat tgaacttatt caaagatggc caagcagatg acgtgatctt
    12781 gtctggtgag ttagcacagc aaaacgcaaa cgatccagct tatacttctg ttaaagaagc
    12841 gcggacaagc tatatcgaat tcaatcaacg tgaaaagaat tcaccattca acaatgtgaa
    12901 cctaagaaaa gctatttctt attctatcga tcgtgaagct ttagtaaaac aagtactagg
    12961 tgacggatca gttgtctcta caggattgat cccatcagat atggtaaaaa gtccaacaac
    13021 gaacgaagac tttgcaaaag aagctggaaa attagtttct tatgacaaag ataaagcaaa
    13081 agaatattgg gaaaaagcga aaaaagaatt gggcgttgat tctttagaat ttgatttgat
    13141 ggcttctgat gatgattcat cgaaaaaagt aatcgaatat gttcaaaact caatccaaga
    13201 aaacttggat ggcgtaacag tcaaaccaac acctgttcca ttctctgtac gtcttgaccg
    13261 ctcaacttcg ggtgattttg acgcagtact aggcggatgg gctgctgact atgcagaccc
    13321 aagcagcttt actgatttgt ttgtcacagg taattcatac aaccgtggtc gctggagcaa
    13381 tgcagaatat gacgaagcag ttaaagcagc ttcatcaaca gacgctggcg atgaacaagc
    13441 ccgttgggat gatttccaaa aagcaatcaa gatcatctct gatgatatgg gtgtcgttcc
    13501 ggtgtaccaa aaagcagaag gtcacctagt gaatgaaaaa atcaaaggta tcgttcacca
    13561 tgcggcaggc gcttcatggg attacaaatg gacatacgtt gaagaataat cgttaatacc
    13621 gtgagcatga gaaaaaacga ggctgcggca aatgtcgcaa cctcgttctc atattcactt
    13681 atcctaacaa agaaaaaagc atgaaaatag cagaaagagc aattagtatt ccggcaatga
    13741 tcagccaaaa gctgtacata ccgtagctgg cagacgagag cgaggaaaat tctggttttt
    13801 tctttcggtt ccttgttcgt gcaagatgga ccgatcgctg aaaatgatcg aagaaacccg
    13861 aagaaaagac ccataaaaaa ccgccgataa tcagaaacgg caatgaccat aagaatagat
    13921 cattagataa ttgaatgagt gtaaaggaat ggttgatgag attttttatt aaaataacca
    13981 gaatcagtag aaaagctact gcgtagggga tagatttttt tttcatttga ttgctccttt
    14041 atttttggtt cattatctaa taatgtagcg aaacatctgt cagaagtcaa aagctagggg
    14101 gaaacattag tgaatagtta tatcaaatat gtattaaaac gtgtcttttt catgatcatc
    14161 acgctttggt taattgcaac aatcaccttt ttcttgatgc aattgctgcc gggcacgcca
    14221 tatacgaatc aggaacgttt gagtcctgaa acaatcgaga tgctaaataa acaagtcggt
    14281 ttggataaac cagttatcgt acaatatggg atttatcttt ctaatttgct tcaaggagat
    14341 tttggaattt ccttccaatt taaaaaccag ccagtcgcac atttgttagc tggaagaatc
    14401 ggaccatcct tgcagttagg gttacaggca attatctttg gaacagtcct agggacgatt
    14461 ttaggaacga tctctgccat gaagcaaaat acatgggcag atacatcttc tacactcgta
    14521 gcgatattag gtcgttccat tccaaacttt gtatttgctg ttttattaca atatatcttt
    14581 gcaatcaaat tacaagtttt gccaatcgca aaatgggatg gctttgtgta cacaatctta
    14641 ccaacaattg cgttggccat gtcgccgctt gctgactctg ctcggtttat ccgtacggaa
    14701 atggtggaag tactgcatag tgattatgtg gaattagcaa aagcaaaagg attgagccgt
    14761 tgggaaatcg cctttaaaca tggtcttcga aatagtttga ttccattgat gactttatta
    14821 ggaccgttag ctgtagcatt gatgaccgga tcactggtgg tagaaaatat ctttgctatt
    14881 cctggtatcg gggaacaatt cgttaagtca atcacaacaa atgattatcc tacgatcatg
    14941 gctgtaacga tcctttactc atttatgctg atttttgtta ttttgatcgt ggatctattg
    15001 tacggtctag ttgatccaag aattcgtgtt tcagaaggga gccgaggata aatggaaatg
    15061 ataccaaagc gttatgaaac agttgcagat atccctgcgg atgaatttct tccattacaa
    15121 aaaaataccg aagaagaacg tgaacagatt actgcacctt ctttgaattt tatccaagat
    15181 tcatggcgcc gtttaaagaa aaacaaagct gccgttattt caatggtttt actattggtc
    15241 atcattttga tctctgtgat cacaatcttt gtttctcctc atgatccaac tgcccaaaac
    15301 gtggcttata tcaatttgcc tcctcgtatt ccgggaatca atatcgatgg attgaatgga
    15361 aaagcaatgg ttggtggtga acttgttgat aaatatgctc aagcaaacgt cccttcaaac
    15421 gtaaatttct ttttaggaac agacggtttg ggacgtgatg tattaagccg cttatttatg
    15481 ggaatgagaa tctcgttgct gatcgcattt attgctgcat tactagatgt aacgattggt
    15541 gtagcttacg ggttggtttc tggtttgtta ggcggacgtg tcgataacgt gatgcaacgt
    15601 tttttggaaa tcttatcagg aattccaaac ctcgttgtca tgattttgat gttggtcgtt
    15661 tttgaaccag gaattttttc aatcgtggct gctatggcca tcacaaactg gataccaatg
    15721 gcacgtatcg ttcgtgcaca aacaatgaaa ttaaaagatc aagaatatgt tttagctgga
    15781 ttgacattag gtgaatcaag aatgaaaatt gcattcaaac atattttgcc gaatatctct
    15841 agtgtcatta ttattcaaat gatgtttagt attccatctg ctattttctt cgaagccttt
    15901 ttaagcttta tcggtttagg tcttacgcct ccgtcagctt cattaggaac gatgttgagc
    15961 gaagggtaca agacattcct gtatctgcct tatctattat ggattccggc agtaacttta
    16021 tcggttatca tgattggctt taacttactt gctgatggat tgcgtgatgc ctttgatcct
    16081 aaaatgaaag agtgaagacg atgacgaaaa ttttagaagt gaaagactta gaaatctctt
    16141 ttgatacgta tgctggaaag gtacgagcga ttcgcggtgt caattttcat ttgaataaag
    16201 gagaaacatt ggcgatcgtt ggggaatctg gaagtggaaa atcagtgacg accagaagca
    16261 tcatgcgctt gctgtcaagc aacgccaata tagatgctgg tcaaatcctc tttaaaggta
    16321 acgatatcgt tggaaaatca gaaagagaga tgcaaaaaat ccgtggtaaa gaaatagcga
    16381 tgattttcca agatccaatg acctctttag atccgacgat gcccattggg aagcaagtcg
    16441 ctgagtccct tagaaagcat aataaagttt caaaaaaaga gggacaaaaa gctgcattag
    16501 aattgcttaa attagttgga atacccgaag ctgagaaacg tatcaacagt tatccgcatc
    16561 agttctcagg aggtcagcgt caacggatcg tgatcgcgat tgcactggta tgttatccgg
    16621 aaatactgat tgctgatgaa cctacaacag cgcttgatgt gactattcaa gcacagattt
    16681 tggagctgct gaaagaaatt cagacaaaaa tcgatacatc aattatcttt atcactcatg
    16741 accttggtgt agtagcgaat gtcgctgatc gtgtcgctgt catgtatgga ggaagaatcg
    16801 ttgaagttgg aacatcggaa gaaattttct acaacccgca acatccctat acttggggac
    16861 tgcttggttc aatgccgaca ttagatagtg cgaacgatcg attgtatgct attcctggtt
    16921 ctccaccgga tttattgaac ccgccaaaag gagacgcatt ctatccaaga aatgaattcg
    16981 cgatgaaaat cgatgcagaa caagaaccac cattttttga actatcaaaa acacacaagg
    17041 cagcaacttg gctacttgct ccgcaggcac ccaaagtgac accgccagaa gaaatccaac
    17101 gtcgctgggc tatctttaaa gagaaacaaa aacatactta cggtcaagga ggaattgctg
    17161 atgccaaata aactacttga agttaaagga ttgaaacagt atttcaatgt aggaaaaaag
    17221 aatgaagtac atgctgtaaa tgacatcagc tttcacattt atgaaggaga aacattcggt
    17281 ttagttggag aatctggaag cggaaaatcc actactggcc gtacgatcat tcgcttgaat
    17341 gaacctactg atggtgagat attattcgac ggtcaagata taacgaagat caaagataaa
    17401 aaaggtttga cgaaattccg gcatgatgtt cagatgatct ttcaagatcc atacgcttcg
    17461 ttgaatcctc gtatgaaagt cagagatatc attgccgaag gaattgatgt taatggacta
    17521 gctaaatcat ctgaagagcg tgcaaaaaaa gtcgatgatc tattgagaac tgttggattg
    17581 aatccaagcc acggtactcg ttatcctcat gaattttcag gtgggcaacg ccagcgtatt
    17641 ggtattgcac gagcattggc agtaaaaccg cgttttatca tttgtgatga accaatttct
    17701 gcactagatg tgtcgatcca agcccaagtg gtcaatttgt tgcaagatct ccaaaaagaa
    17761 catcaattga cctatctatt tattgcacat gatttgtcga tggttaaaca tattagtgac
    17821 cgaatcggtg taatgcataa cggcttgtta ttagagatgg gaacaagtga tgaaatctat
    17881 aatcacggtg ttcatcctta tacagaaagt ttgttatctg ctattcctct accagatcca
    17941 gaccatgaga gaaaacgcag aagaatcaaa tatcaacctg aaccagatga cggacaagta
    18001 cgtcaacttc gtgaaatcgc accagaacat tttgtctatg caactgagca ggaagtccca
    18061 tattacgcaa aaaaactaaa acgacaaaag gaatctcttc tggttgctaa ctaggaggga
    18121 catagatgct aaaagctttt aaattccgta tgtatccgac agaagaacaa aaacagcaat
    18181 tgattcgtac ttttggatgt gctcgattta cctataacca tttgctgaaa aagcggcaga
    18241 aaagttggca acaaacagga gtagccaatt tttcgctcac acccgctaca ttaaaaaaag
    18301 aatacccatt cttaaaagaa gtagacagtc ttgctttagc aaatgcacag cttaatttgg
    18361 atcgggcttt tcgcaattat ttcaagggac gtgccagctt cccaaagctt aaaacgaaaa
    18421 aaagtatgtg gcaatcttat acgaccaaca accaaacccg tacgatctat ctggaaaatg
    18481 gctacttaaa gttaccaaaa caaaaagaac taatcaagat aaatcagcat cggccagttg
    18541 aaggatcgat tcgctccgct acgatttctg ctcgatataa tgaagaattt tatgtcgcac
    18601 tactttgtga tgtttcgcca gtaaaaaaag aatctttagc taaatggatc gggatcgcct
    18661 atcatccgaa gacattgatc caaacatctc gacctctaga agtaacttta ccaaaatttc
    18721 accagacaga agaaaagctg caacatgcac agcggaaatt gaatgtgaaa gtccgctccg
    18781 ctcaccatag aaagatcagg ttagatcagg caagcaatta tcagaaacaa aagagaaaag
    18841 taatggatct ttatctgaaa caaaagaacc agcgagaaga ttatcttgaa caattatctg
    18901 ggaaattggt caaacaatat gactacttat ttgtagaatc ttttccaaaa gaagaggcac
    18961 atgctgattt ttctattcac gactggcata aattaataac aaaattgcgt tataagtccc
    19021 aatggtataa taaaaaattt cttttgatca ataccgacgg agcagaagaa agcaattccg
    19081 taagaaagag ccaagtagta gaaaaaatgg gcagacattc ggttatcaag ggataaaaaa
    19141 tgaatgaaac tgataggagc gttagggtta gccttgttaa taaaaagtct taatgacttt
    19201 tgtttctagg aatttttctt ttgaagaaaa gctcactaat tatgacaaac caataaaaca
    19261 atagcagaaa aagttcgtac gagctttttc tgctattgtt aattttttat tcagaaagtt
    19321 tacgaataca tcaaaattct gaaacaaaaa acgtaactca caaagagttg tttttgcgtt
    19381 ttttcttgaa tgattaggtc tgaatctttt gctcacaacc ttattcatgg tgccccggct
    19441 tgagctgata gatttttgaa ggacggccga ttcctacagg acgttcaccg atctcatcga
    19501 aatattggag catagctttc ttaaaattgg aatgatcgat cgttttataa tcgatcccta
    19561 agaatttagc aaatactttt cgagcttccg taatcgtgaa atctttacct aaaacttgta
    19621 gaacttgcgg ctcgtgttcc attttattga ctacacggtt gaatgctttc aagatgattt
    19681 gactatggtc aaaagccaaa gtatctttgc cagaagactc tccagtgact aaatcaagcg
    19741 agatagccac ttctccgcta gataaatgga tcttgttact atgacgttct agtgtgaacc
    19801 agcgtacttc cttggcatca tctccggcga ttagcggttc ttctccaata aaggctaagt
    19861 agctgactgt gacgacccag cctcgcggat ctcgattagg cgtactgaat gtatgcagtt
    19921 gctcaatatt ttcttttgaa ataaccacac cagtttcttc ctttgtttct cttaagacgc
    19981 tttctccagt tgactcatcc ttttggacaa agccaccagg caatgcccat gaatttcgat
    20041 aaggatgccc ttttctttgg atcaacaaaa ctttcagctg atcttcttct ttgttatagc
    20101 acatcagtac gatatcgaca gtcaaagagg gcttgtcata ttctggacgt tcctgttttt
    20161 gataccagtt aagaaattct tcttcacttg ctttatgttc ataatataat ttttcttctt
    20221 ctttagaagc aaaacggttc atctgaccac ctccattgac agtaaaagta ctttttacct
    20281 tattgtagca gactctgaaa aaaaaccaag gatttacttg aaaaatctag gttatcattt
    20341 aaatatgaaa aataaatgga agtatgagat tgaataaaaa gaaaagcaga taaaacggca
    20401 atactttata ccgctcttca cgaatggcaa agaagccaca aataacgata tatacgtcaa
    20461 tgataaaacg caaaatccaa gctgctgtca taaaactgtt caaatgccca tggaggttaa
    20521 aataaccata catacgaata taaaaatagc tgaatattaa atgtgctaat gaaagaaaag
    20581 caatactaag tgtaaaaaaa agatgtttct tctgcatgat tgttccagtc ccttactaag
    20641 atagatagtc tttattatac cacgtgtgag gggagaaata aaaagccgtt ttttagtaga
    20701 tatgaaacaa aacaaaaacc cgcatttatt caacctattc atccttttaa aggatagatt
    20761 gaacgtagat agaagtcgtt tatccagtct ttttcatttt gaaaaaaagc taacagcatg
    20821 ctttttttat ggtatactag caaggaaacg aattcgcatc atgcgataaa ggaggaagag
    20881 ccccgtggca gaaaaggaaa ctttttatat cactacgcca atctattatc caagcggcaa
    20941 acttcatatc ggcaactcgt atactacgat tgcatgtgac gcaattgctc gttataaacg
    21001 gttgatgggc tttgatgtgt tttatctcac tggagtggat gaacatggtc aaaaaatcga
    21061 aacaaaagca gaagaactag gtgtaaaacc gcaagaatat gtagataaaa tggcggctga
    21121 tgtcaagaaa ttatggaaaa cgcttgatat cagttatgat aaattcattc gcacgacaga
    21181 tgattaccat aaagcagctg ttcaaaaaat atttgatcgt ttattagaac agggagatat
    21241 ttacttaggt gaatatgaag gctggtactc tgtttctgac gaagaattct ttacagaaac
    21301 acaacttgca gaagtgtaca aagatgacga aggtaacgtg atcggtggta aagcgccaag
    21361 tggacacgaa gtagaattgg taaaagaaga atcatacttc ttccgcatga gcaaatacgc
    21421 agaccgtcta ttggaatact atgaagaaca tcccgaattc atccagccag aatctcgtaa
    21481 aaacgaaatg atcaacaact ttatcaaacc aggattagag gatcttgcag tttcacgaac
    21541 aacttttact tggggagtac cagtcaagag tgatccgaaa catgtggtgt atgtatggat
    21601 cgatgcatta tccaattata ttactgcact aggatatggc tccgaagatg aaagtctatt
    21661 cgaaaaatac tggcctgcag atgttcagat ggtcggtaaa gaaatcgttc gctttcatac
    21721 gatctattgg ccaatcatgc tgatggccct tgatttgcct ctacctaaaa aagtatttgg
    21781 gcatggctgg ctattgatga aagacggaaa aatgtctaaa tcaaaaggaa atgtcgttta
    21841 tcctgaaatg cttgtggaac gttatggttt agatgcactc cgttattatt tgcttcgtgc
    21901 tgttccgttt gggtcagatg gtgtctttac gccagaagat tttgtttccc gtgtcaatta
    21961 tgatctggca aatgatctag ggaacttatt gaatcgaacg attgctatga tcaacaaata
    22021 ttgtgatgga ctcgttcctg actatgcctc acttgtcact ccatttgata gtgaactgtc
    22081 tacgacggct gctaacgttg tcggacgtta ccatgatgca atggaaaaaa tggaattcaa
    22141 tacagcattg gctgaaatct gggtgctgat ttctcgtgca aacaaataca ttgatgaaac
    22201 agaaccatgg gtattagcaa aagacgaaga aaagaaagct gaattgaata gtgtcatgat
    22261 ccatttagct gaatctttgc gtatcgcagc gatattactt cagccaatca tgacagaaac
    22321 gccagagaag atcttcaatc aactaggatt ggactctgaa acaatgaatc ttgaaggatt
    22381 acactttggc gaatttcctt caggaacaaa agtagttgca aaaggtacac caatcttccc
    22441 acgtttagat atggaagaag aagttgcttt tattcaagaa aaaatgtctg aaggtactca
    22501 aacaaacgaa gatacagtca aatgggatcc agaagaaaca gaacttgttt caacgaaaga
    22561 aaaacaaatc aaatttgatg tatttgaaaa agtagaacta aaagtagcag aagtcatcaa
    22621 ctgtcaaaaa gtagaagggg cagataagtt gctgcaattc cgactagatg ctggagacag
    22681 ccaagaccgt caaatcttgt caggaatcgc tgaattttat cctgatccaa gcgaattgat
    22741 cgggaaaaaa gtcgtcattg tagcaaatct gaaaccacga aagatgcgtg gacaaatcag
    22801 tcaaggaatg atcctttctg cagaagcacc agatggctct ttacaagtaa tcgaagcacc
    22861 aaaatccatg ccaaatggct cagaaatcgc atagaaattc aaagggggta tgacactagt
    22921 tgtgtcatac cccctttttc cgaaatttga gaagcaattt tcgtaaattc cttcttatta
    22981 cttgaagcca atcatataat acagaaacag agaactatcc aaaataaatc ctagaaaaag
    23041 aagtacgagc ttcgctgatt tttgttaatt tagaataata ctaataggaa tcgtaaaaac
    23101 agaaaaaaag cataatgata aagggtcggg cagattttaa ttgattcatc tggtactctt
    23161 ttttattgtc cttacattca taaagtttga atgcaatgac tttattacat ctatatttat
    23221 atctaacagt agcgttgatg tgttaattat aagttctatc actttatgtt caattagttt
    23281 gtgctcttat atgtgtgatt gaaaatatag ataaaaaaac aatcatcggc tttgacttcg
    23341 atgattgttt tctttatttt gtaaaaatcc tatcacttga ttttatggta accttttatt
    23401 tttgtcttca aacggcttgg taagagagca gtaagcagtg caaatgggat cgaaaagaca
    23461 taccagaaaa tcgtacgtcc gataccataa tgttgataga gctttgtcaa catcacgtgt
    23521 aacaagatca accctaaaag caaggagcca gctataaacc aatgattatc ccaatgcatg
    23581 acttcactaa gtgccatcac tccaaaagga tagaaataaa aatagatccc gactaaggtc
    23641 atccgccagt tctttgtaaa tgttccgata ttcaataaaa agaaaatcgc tgaaagcaaa
    23701 ataccgatag gcggaaaaag cccaaccaaa aaggaataca acatccccca caagatcatc
    23761 acaggacctt tgatcaatgc aacgattgcg atgaacaaag tcagcaatat tagtttttgt
    23821 gataacgttg caacagtcat taatccaaat aaaattaatg tgaaccaatg ccaatgggac
    23881 tgctgttgtt ctttacggga aaaatcgacc cggttggata aataatctgc taatttcgga
    23941 taagaacgct taaaatccat aaactgttcc tccttcgtgg aaaaggtagg tttagtatac
    24001 gaaaaataaa aaagaaatac atccgtctta agagggagtt tttcactgaa agtggagaaa
    24061 aaagaatggt aaattaaaat attctcagtt atactgaaaa ttataccaaa tttcaaagaa
    24121 gaaagaggat gggaatgaaa ggcaaactaa aacgagaaat caatctgttt ggcgcattag
    24181 ctaccgttat gggaaccgtg atcggtgcag gcgtcttctt caaaactgct gctgttactg
    24241 ctagtactca gtctacaagt ttgacattgc tagcttggct tttgggtggt ttcttaacga
    24301 tctgtgctgg attgacagtg gctgaattag ctacagcaat cccggaaact ggtggagctg
    24361 taaaatatat tgaagctgcg tatggaaaat tgcccagctt tttattagga tgggcgcaaa
    24421 gcttgattta ctttcctgct aatattgctg cattatcgat tatctttgcg acacaattga
    24481 cgaacttatt acaattatct accgattatc ttttgttgat tgcagtgatc accgctgttt
    24541 ctgtgacagg gttgaatttg ttagggacaa aagtcggtgc ttctgtacaa tcagtgacgt
    24601 tgattgttaa attaatacca attgctgtga ttgtcatatg gggattattg accccaggac
    24661 aaggaactgt ccagttattt ccaatcgaag ctggaaaaga tgttactttt gtcgaaggat
    24721 tgagcagtgc gttgttagca acgttgtttg cttatgacgg ctggttaggt gtcggtgcaa
    24781 tggcagggga aatgaaacgg ccggaaaaag atttgcctaa agcaattatt cttggtttga
    24841 gttttgtaac agtcgtttat ctattgatca attttgtttt tttgaaaact ttgccgattg
    24901 atcatcttgc cggtaatttg aatgcagctt ctgaagcatc agacgtcatt tttggaggaa
    24961 tcggtggaaa gctggtcact attgggatct tgatctcggt atacggtgca ttgaacggtt
    25021 atacactaac tgggatccgc gtgccttatg cgatggcttt agaagacgag ctacctttca
    25081 gtaaacagct gacaaagctt tcaaagaagt ttacggttcc ttatgttcct gcggttttcc
    25141 agttagcagt agcttgtatt atgatgagcc ttggttcttt cgacttttta acagacatgt
    25201 tgatttttgt gatgtggcta ttcagtttac tgatttttat cggtgtcttt attttaagaa
    25261 aaaaagcgcc ggaattgcca cgtccatata aagtaccact ttatccaatc gttccgatta
    25321 ttgcgattct cggtgctatt ttcattttag gtatgacgat gatgacgcaa acgaaattag
    25381 cattgatcgg tataggtgtt accttgatag gtatcccagt ctattatcaa aaaaagaaaa
    25441 aacgctcaga agagtaaaat atttcaacaa cagacagaaa aagtacgaac taggtcctct
    25501 agatcttcgt gctttttcta tttcaataaa acaagttctt ctattttgat ttttgctact
    25561 tctgcaagta gtgcttatgt gctaaagtaa gaatgaaaag gagagataaa catgatattt
    25621 gattctcata cccatttaaa tgctgaacag ttcaatgaag atattccaga aacgattcag
    25681 cgagcacaag aaatgggggt aacgaaaatg gcggtcgtgg gcttcgatac gccaacgatt
    25741 gaaaagtctt tgcaattaag ccatgactat ccaaatatat acagtattat cggctggcat
    25801 ccgacagagg ctggcagtta tacgaaagaa atcgaaaata aattacaaga acaattgact
    25861 ttaccaaagg ttgtagcatt aggggaaatt ggcttggatt atcattggat ggaagacccg
    25921 aaagaagtcc aagataaagt atttcgcaga cagattgcta tcgcaaaaga aatgaaccta
    25981 ccaatcagta ttcatactag agaagcactt gaagacacgt atcaaatcct aaaagaagaa
    26041 gatgttcgag atatcggtgg aatcatgcat agtttcagtg gtgattatga atgggcaaaa
    26101 cgatttcttg acttagggat gcatatttca tttagcggtg tcgtcacttt caaaaaagca
    26161 ttagacgtcc aagaggctgc agcaaatgta ccaatcgaac gattacttgt ggaaacagat
    26221 gccccttatc tggcaccagt tccttttaga ggaaagcgaa atgaaccagg ctatactcgt
    26281 tatacagtag aaaagattgc tgaacttcgg aatcttccga cagaagaagt ggctgcccaa
    26341 acatggacaa atgcgcaccg attatttggt ctaagcgaac atggataaga tgaagatcca
    26401 agagattata gtcgttgaag gaaaagacga tacaagaagg ctgcgggaag tagttgatgc
    26461 agatacgata gaaacaatag ggtctgcaat caatgaagag atcctgatgc aaattgaaca
    26521 tgcccaagag actcgtggag tgatcgtttt taccgatcct gatttttcag gagaaaaaat
    26581 aagaaaaatc attatggaag ctgttcctca ggcaaaacat gcttttttgc cgcgcacaca
    26641 agctaaacca aagaaaaagg gaagccttgg tgtcgagcat gcaagtgatg ctgctatttt
    26701 agaagcattg aaaaaggtcg tgacgccaga catttcccaa acggctgttt ctgaaatcac
    26761 tagacaagac cttttagact atggtttaat agctggggca caagcaaaag aaaaacgaga
    26821 aaaactaggt gacgagttgc gcatcggtta cacgaacggc aaacaattgg aaaaacgttt
    26881 gaagatgttt cgtattacgc cgaaagaact cgcccaagca atgaaaatag tggaggaaca
    26941 acatgagtga atatcgtgaa attgcgacac cctctagaac aaaagagatt ttattgaaac
    27001 atggtttttc atttaaaaaa agtttaggac aaaattttct gactgaacca aatattttaa
    27061 ggaaaatcgt agaaactgcg caaatagatg aacatacgaa cgtgatcgaa gttggaccag
    27121 gaatcggtgc attgacggaa caattagcca agcatgcaaa acaagtcgta gcatttgaga
    27181 tcgatgatcg tttgatccct gtattggctg atacgatgca accctatgac aatgtgacta
    27241 ttgtacatca agatatttta aagaccgatt tgtcaacagc tgttagagaa acatttcatg
    27301 aggagcttcc gttaaaagtc gtagcgaatt taccttacta tattacgaca ccgatcatga
    27361 tgcattttct tgaatcagat ttggttgtgg atgaactagt cgtcatgatg caaaaagaag
    27421 tagctgatcg tatctctgct gaaccaggaa cgaaagctta tggttcatta tcgattgctg
    27481 ttcaatatta tatggaagcc agtttagcat tcatcgtacc aaaaacagta tttgtccctc
    27541 agccaaatgt agattcagcg attttgaaac tgacaagaag agatataccg gcagtcgaag
    27601 tgacagacga aaaagcattt ttccgattga caaaagcggc atttcagcaa agaagaaaaa
    27661 cgctttggaa taacttgcag cattcgtatg gcaaagatga ccagacaaaa gcatggttag
    27721 caaaaagctt ggaaacagct ggaatcgatc caaaacgtcg tggggagact ttgtcattac
    27781 aagaattcgc cgcattaagc aatgcgatgt cagaaaatat gcagtaaaaa aagaggttgt
    27841 gacagaagtt gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa acaaaaatag
    27901 ttcctcatgt ttttcgtttg tttgggctta ttaccgcaga tgcaagcttt tgaacaccgt
    27961 ttaagaaaga ggttgtgggc ctgccgttta actctaagtc acaaggaaca atttcaaaaa
    28021 acagcttctc atgtttttga gttagttggt cttattactt gatgcaagct tttgaccact
    28081 attatgccga acaaggagat gtgacacaaa ttttgtcaca tctcctattt ttgtttcttg
    28141 atcaaaaaat tcttatactt gatactcaca ctcattttgt atggatttag aaaagaatat
    28201 gtgtcttgac agttattagt aagtgagtta tactaagtcg acatttatgt gtcaagacat
    28261 attaggagag agaaaaaatg agaaaaaatt cagttcgaaa actaacgatt tctgctttat
    28321 tgattgggat gggggtcatt atcccaatgg tcatgcctaa aatcatgatt ccaccagctt
    28381 cctttacttt ggcgtctcat gtgccattat ttattgcgat gttttttaca ccaggagttg
    28441 cagtggctgt tgcgctaggt acgacatttg gtttcttttt aacaacgccg gttatcatcg
    28501 cattgcgagc attgtcacat cttgtgtttg cgttgattgg ggcttggtac ttgcaaaagc
    28561 atccgagtat cgttttaaaa aatggacagt ttacttttgc taattggcgt ttccaagggt
    28621 tcaattttgt gatcggtgtg attcattctt tagcagaaat gctagtagtc agcatctttt
    28681 actttattgg taatatgcct gaaacatatt attctcaagg atatttttat acagtattca
    28741 tcttgatggg gattggtggg cttatccaca gtttagttga ttataatatt gcttatttta
    28801 tagcaggaac actcagcaaa tattttgata tccccgtatt tacggcagca aaaaaagaaa
    28861 atcggaaaga gtcgattcaa gggtacgcga agaaaacgac atattagaca tgatctctca
    28921 aaaaaaaaac tctcatctag taatggataa taaatcctct aagatgagag ttttttgtcc
    28981 taaaaagagc tgcaccaaca tcttctggca cagctctaac agggggcaat ttatggaagt
    29041 ttgatgactt gttctgtttc tttatcaaag aagtggcctt tgctgatgtt gaaggcaagg
    29101 tcgactattt cgcctggttt atggaaatct cttgcatcta cttttgagat gaactcagta
    29161 gaaccagttt ttgtgtaaag catcgtttca gctccaagta attcggaaac gacaacttct
    29221 gatttcacta cggcttcagg tgaagcttca agggctactt gttcactgtg gatgtcttct
    29281 ggacgaatac cgaagataac ttcttttcct tcataacctt tttcaactaa tactttgttt
    29341 tttccttcag gaatacgaag cttaagccca tgtccatctg tgataacacc atttttcaat
    29401 gtcacattaa agaagttcat ggcaggagat ccaataaagc cggcaacgaa catattgacg
    29461 ggtgtatcat aaacttcttt cggtgtaccg atttgttgga taaatccgtc tttcatgata
    29521 acgattcggt cagccatagt cattgcttct gtctgatcgt gagtaacata gatggtcgtt
    29581 gtttcaagac gctggtgaag tttggcaatc tcagcacgca tggctacacg taatttagca
    29641 tctaaatttg ataatggctc atccattaag aagacttttg catcccgaac gattgcccgt
    29701 cccaatgcca cacgttggcg ttgtccacca gataaagcag ctggttttcg tttcaagtat
    29761 tctgtcagac ctaagatctc tgctgcattg tccacacgtt ttttgatgtc tgctttatca
    29821 tatttacgta atttcaagcc aaaagccata ttatcaaaaa cagtcatatg aggatacaat
    29881 gcgtagtttt ggaaaaccat ggcaatatca cggtctttag gtgccacgtc attcatgact
    29941 tttccgccga tatttagttc tccttcagag atatcttcca gtcccgcgat cattcgcaaa
    30001 gtagttgact ttccacaacc ggaaggacca acaaaaacga taaattcacg gtctttgatt
    30061 gatagattaa aatcagttac agaataattt tctgcattgt catatttttt atatacgttt
    30121 ttcagagcca tttctaccat aatacgttcc acactttctt ttttagtttt attaactatt
    30181 taaagtataa atgaaagcgt taactaactt caatgtcatg ttgaacaaga attttttctt
    30241 ttttttgtca atgtgctagt tttaagcttt aataaatatc cataagaaat aaaaactgat
    30301 acactggagt aaataagtat gttaacaata tcaaaaggag tgtctcttat gaaaatcgct
    30361 ttgatcgctc atgaccgaaa aaaacctatg atggtgaaat tagcaacagc gtataaaaca
    30421 atattggaaa aacatgaact ttttgctacc gggacgactg ggcagaggat cacggaagca
    30481 accggcttgc cgatccatcg gtttaaatcc ggaccgttag gcggggatca gcaaattgga
    30541 gccatgattt cggaggatca gttagatttg gtgatttttc ttcgagaccc gctggctgca
    30601 cagccccatg aaccagatgt aacagcactt atccgtttat ctgatgtcta tgagattccg
    30661 ttagctacga atatcggaac agctgaggtg ctactaagag gactggaagc cggcttccta
    30721 gattttcgaa gaatcgtcca tgaaatagac aagcatccac tttcattttg atggataagc
    30781 gtatggaaaa ataacgttta atgttcgcct atatgtagct ataaaagcta aacaaactga
    30841 taatatgcga tataatacga acgtattgga taatataaac aataatatta gtttttcgta
    30901 tttgcagtaa atgtgaaaat atgctatagt ttctgtggga aaagatccca aaaataatac
    30961 agagtagaaa ataaagcgtt aagtgctaag aggatgggat gttgcctctt ggacgaagga
    31021 cgtaatgttc gcggttttat tttcgcattc gctgcatgat acgatgtagc agctcttaaa
    31081 ggagatgcta aaaatgaaga aacaccggtt agacgcacgt atgattgcta ttatgggctt
    31141 attgattgca ttgatggtca ctttgtcccg actggtagca atcgagaccc catttattaa
    31201 aatcagtgtc acatttattc cacaagtgat catgggcatt ctttttggtc ctttttggtc
    31261 agggataggc gcagttttag ctgatttagt aggaatggcc ctcttctcga aatctgcatt
    31321 ctttattgga tttacattga atgcatttat tgaaggagca atctacggat tctttttcta
    31381 tcgaaaagag atcacttgga aaaatgccat tctggctacg cttagtgtca cgctgatcat
    31441 caacttattt ttgacaccat tatggcttgc gttgatgtac catgtgccat tgttcagctg
    31501 ggtcgtttgg gcgccccgcc tgttaaaaac agtaatatgg ttaccgattc aatcaattgc
    31561 catttattac gtaggacgta gtattcctta caaaaaaatt ttaagaagtt tagcgatcca
    31621 cgctaaataa aaaacaagca gtcttcccat cccagaagac tgcttgtttt tattgtgctg
    31681 tgaattgtgc ttgatagagc cgtcggtaat aaccatcttt ttgaagcagc tcatcatggg
    31741 tgcccatttc gacaatagct ccctgatcca tcactaatat ctggtccgca tttttgattg
    31801 tggacaggcg atgggcaatc acaaaactgg tttttccttc catcattgct aagaaggctt
    31861 gttggatttt tttctctgtc aatgtatcga ctgagctggt agcttcatct aagatcaaca
    31921 tagggggatt actgatcatc gttcgagcaa tcgtcaacag ttggcgttgt ccatctgata
    31981 tctttaaccc ttgaccgcca atcttagtat ctaatttttc cggcaaacgt tctacaaatt
    32041 catacatata agaggctttt agggcatcat tgatttctgc gtcacttgct tccggattcc
    32101 caaaacgaag attttctcgc aatgtactgt caaatagcca agtatcttgt aacaccattc
    32161 caaaactttt acgtaatgta tcacgttgga tagagcggat gtcatggtca tcgactgtaa
    32221 ttgttccttt tgttgtgtca taaaaacgca tcagcaaatt aacaagtgtg gattttccgg
    32281 cccctgtttt tcctactata gcaatggttt gacctggata agcagtaaaa ttgaaatctt
    32341 cgatcaaacg ctgcttgggg tcataagaaa aagaaacatg atcaaaagag acttttcctt
    32401 tgatattttt gggttccaag gcataggcat ctggcaaatc aggcttttct tctggctgat
    32461 cgatcaaatc aaatgctcgt tctagaccag aaaaagcggt ttgcagttgt gtcgtgattc
    32521 cagaaagttc gataaatggt ttagaaaact gacttgagta gatcgtaaag ctggaaatca
    32581 caccaacagt gattgacgaa ccactcttca atgccaatag gccgccaact aaaccaatcg
    32641 ataaataagc aaggtgatct acaaaacgag aagacgggtt tgtcaaggaa gaagaaaatt
    32701 gtgcccgttg tcctttttca tatagatcag catttagcag ttcaaattgc tgttgactag
    32761 cttcttcttg ctgaaaagct ttcacgattt tctggttacc gattcgttcg gtcacaaagc
    32821 ccgagatatc cccaataatc ctttgctgtc tatcgaaatt tgtttgtgaa gcacgagcaa
    32881 cgatccaact cacaaggaaa ataattggtg tagaacaaag aacgaccaat gtcagaagtg
    32941 gacttagacg catcataaaa ataaacgaaa gaatgatgat tgccactcca gaaaataatt
    33001 gattgaaggc cgcagaaatt gcaatggaaa tattgtccat atcatttgta aatcgactga
    33061 cgatatttcc gtgggagttt tgatcataat aacgaagtgg caatcgattc agatgagcaa
    33121 atgcatcttt tcttaatttt gcaacggata agtaagctaa ccgattgctt aacacttgga
    33181 tgagccattg actgactacg ttgattaaaa cgataccacc gaatagaata agtaaatgga
    33241 acagtcgatt gaagcggacc tgtccttctc caatcatttg atcgatactt tgaccaattt
    33301 gtaacgtcat cacaactgtt gcaatcccat tgatgattcc tagtatcaca gctagccaaa
    33361 tgtcttttgc ataggcagta aggtaaggaa tgaatcggcg gagcgtctgc aaggataatt
    33421 tttttacttt cataactatt cttcctcctg tgatgcgacg atttcctgat attctgctga
    33481 ttgagcaagt aattcttcat gggtaccctg agcagcaatc ttaccttgat ccatcactaa
    33541 gatatgatgt gcttcttgaa tagagcggac acgttgggag ataataatca ctgtactgcc
    33601 aagataagtc tgtagcgcct tacgcaaatc caagtctgtt tgataatcca acgcacttaa
    33661 agagtcatct aaaatcagta atgctggctt ggcaatcaaa gctcttgcaa tcgtcagtcg
    33721 ctgtttttgt ccgccagaga aatttttccc attttccatg acttttgtat ctaaaccatt
    33781 tggaagctga cggacaaatt cttctgcctg agcgattttc agagcttccc aacattcttt
    33841 ttctgtggcg tctttcttac cccattgaag gttttcacga atagtcccgg taaatagtac
    33901 agaagtttgg ggaacaagag caatttgctg acggagatga tccagctgcc aagaacgaac
    33961 atccattccg tccattataa ctgtaccgga actgacatca tagaaacgcg gaatcaattg
    34021 tgtcaaagtc gttttcccgc ttccggttgg accaatgatt ccaaggactg tatttcgctt
    34081 cagctgaaat gtaatatttt ggagagaaag accagaatca ggagtataac ggaagtcaac
    34141 atggtcaaaa gcgataattg cttcagaaga aaaatcggga gtagtactga cctcagcttc
    34201 aagaatcgaa ttttctgtgt ctagcacctc tttcacccga tttcctgaag cttcggcacg
    34261 tgtgaagatc acgacgaggt ttgaaacaac gatcagtgcc aaaagcattt gattcatata
    34321 attgatcaaa gcaagaactt gtccttgttg caagctacca atatttactt tgatcccgcc
    34381 aactgtcagc aaacagatga tcccgacatt catgatcaag gttgtagcag gtgataatag
    34441 ggcagagata ttggaaacac gtaaataatt gttcgctaga tcatttgtgc ttttatcgaa
    34501 cttctctgtt tctttttttg tctgcgcaaa tgcgcggatg acacgaacac cgctaagatt
    34561 ctgactaacg tgttcattga gctgatctag tttttcttgc actttttggt agagaggaac
    34621 ggtttttttg atgataaaaa ataaaatgat tgagaaaata ggcaataatg ctaagaaaaa
    34681 cagacctact tcccagtcga tcacaaaagc catgaccact gacccgatac ttaaaaacgg
    34741 tgctctgatc aataaacgaa tgaccattgc taaagctagc tgaagctgat tgatgtcgtt
    34801 tgtcattcgg gtgatcaagg tatctgttcc aaaatgattc aactcgttgt gagagaaagt
    34861 attgattttt ttgattagct gattacgtaa ctctgtacca aatccttgtg aagctactga
    34921 agcatagtat tggcaaatga tagcacaaat cagaccaatc acagacatag cgaccatcca
    34981 taagcccatt tcaatgattt ttcctcggtc attcattttt agtccattat cgatcaagga
    35041 agccatcatt aaaggcagga caagttcgaa gacagcttca agaaatttga agaacgggcc
    35101 caaaatgatt tgcttacgat agtcttttgc ataacgtaat aactgaatca tatgattcct
    35161 cctattattt atttgtccac aattgaaaaa acaagtacta ccacattgta gcttaggaaa
    35221 tttagaatga aaagagaaca agccttttca taaatgaaag ttttattatg aagaagcttt
    35281 agaaattgaa tagactattt tttttaaaaa aaagaaaatg agaaaacatg ccagtctctt
    35341 cattcatagg aacgtctatt ttacttaatt tttctataaa tgaattctgc ataaaaaata
    35401 tatcaagtaa atgtttatag atgaaactct atttacttct tttttaattt gttcttgcaa
    35461 tcttttttgc tacgtaattt ttgtaaaaaa gtgggttgag agaaatctaa ttgattttca
    35521 aagaaggagt atgaaaatga gaaaaatatt tattcgttta ttgtgggtac tatcttagag
    35581 gaataaataa tagtggagaa aactatggtt tggcgcagat tctatcaggt ttgatggaac
    35641 gaagacaacc tcccgacatc aagtcaaaag ctacttgaga ttttgatctg aaaataaaaa
    35701 aagaaaacaa ggtaggaaca tcaatgtttc taccttgttt tcgtaatcaa tgggaaaaaa
    35761 ctaagagtgg tgtacgtaat caataaaaag gatggtgaca acagtacctc tttactctct
    35821 gaaagcatca taactcgttt ttcctcatta tgccaataaa ttgttgttat accacatata
    35881 aggatttgta atagctaaaa acagacagga aagttgaaat ctgtgaatct tattttgtat
    35941 ggaaggattt atagaacgca aaaatcaaga taaagatgaa taaaaatcct gtttcggcta
    36001 tatattgcgt atctacgcca ataaaacgag tttgttctgt catagccata taaagcaaag
    36061 gcaaaaatac aactacagcg agataagatc cgatgatttc tcgaaaagtt ttccaggaag
    36121 tatgtttcct gtttttatat ttatccgatt tcattgaata gtcatagcct ccttattctt
    36181 tcatatgttg aaattccagt ataaaaactg gaaggaactg tacgtttttt agaataaaaa
    36241 ttataaggga taagtaggct gctgtctata ataagatata tttttcaatt ctttattaaa
    36301 gattttattg acaaaatgaa tccgttttct atgatggagg aggggtgaat aagttgttga
    36361 agaaggaaat tttatgttac ttagagaacc agacagcctt tttcgattta gaacatatga
    36421 acgaggtctt tacagcacaa aggttagctg atcattttgg ggtaaaaaga aacacagtca
    36481 gtcattattt gaaccagtta aatgatgagc aactactagt caaaatcaat tctcgaccag
    36541 tgatttattt ccacaaagaa gcttttgaaa aacaattttt taagttacgc acgaattttt
    36601 atttttctat cgatgatctc aaagaggaac agcctttttt cgcgcaacca aaagacttat
    36661 tctcttttat gatcggatac gacgccagtt tgaaagaaag tatcgaacaa atcaaaacag
    36721 ctctttacta tccagatggc ggattaccac ttttgattac aggcgaaagt ggcacaggta
    36781 aaagttattt agttaatttg gtctatcagt attgtctgct tcatgatctg ctagaagatt
    36841 ctgcaccatt catcactttt aattgtgcac aatatgcaga taatcctgaa cttttgacta
    36901 gcaatttgtt tggacatgtt aagggagcgt acactggtgc agaagaaaat aaaaaagggg
    36961 cttttgaagc agcagatggt gggatcttgt ttttagacga ggtacatcgc ttaacaccag
    37021 aaggtcagga aaaactgttc acctatcttg atcaaggtgt gatttatcgt atgggagaac
    37081 ctaatttgtc acgccggatc aaaacacgtc tcttttttgc tacgactgaa gagattacta
    37141 gtcatttctt aacaactttc attcgaagaa tacctatccg aatcgaacta cctgcactta
    37201 atcagcgtag tcgtaatgaa cggctagaac tgatttactc tttttttctc gaagaacaaa
    37261 gaaaaatggg gagccctttg tcagtcagtg gaccagcttt gtcactttta acaagtcaga
    37321 aattatccgg aaacatagga gagctgaaaa atatcgtcaa agtttcagca gcaaaagcat
    37381 atgctgaaca gcgtgaacag cctgaaatcc atgtcacgat ccatcatttg caaaaagaac
    37441 tacttgcgca gcctattact aaaaatacag cacagcaagg aatctatatt acgcaagacc
    37501 agaccttaga gcaattaatg gagaagcaac agcccgaaca gcagcgaatc gttaaaagtt
    37561 ttgagcaaat cctaattgat ttcaagaaaa ataactgtct gctatattct tgcgaaggaa
    37621 aattaaagca agaagtgatt caattatttg attttttgct gtttgagacc agtagacaag
    37681 aaaaacacga gctgctggtt tattggacac aatctatccg agagaccttt cgacaaatgg
    37741 aaactgccta tcaaatcaaa ttcgatggaa acagtgtcta tgccttgagt tactatctct
    37801 atcagcgaag cactatcaaa tggttaccgg aagaacatga tattatccaa ctaatcaaag
    37861 aattagaaca acaagtttct cagtcttatc catctagtta tcactatgtc caacgaattc
    37921 tggaattaag taagatcaaa ttagatattg aagacacaag tatggatcgg attttactga
    37981 cgatctatct aaaaaaagcg aaatggtcaa aagaaaaacg actgccaaaa gcgatgattg
    38041 ctgctcacgg ttatgcaact gctagcagta tggcaaatgt agtaaatcgt ttattacaag
    38101 aggatctatt tgaatcattt gatatgccac tagatgtcac accacagcag attgcttcag
    38161 aaatccttga ttattgcgaa aacagcgatg tttcaaatgg attgatcata ttagtagaca
    38221 tgggatctct gaaagaaatc catcagtttt ttaaaaaaca gttatccgta ccgcttttga
    38281 ttttgaataa tgtgacgaca cctttagcaa tcacagtagg ggaatgcctg caaaaaaatg
    38341 tatcattaga agagatagca gaagagactg ttcgacagat ccagccagaa tggcgactgc
    38401 tctatccaga ggaaaacaaa cccaaagcac tcattactac ttgcttcact ggaatcggta
    38461 cggcggtcca cttaagtgaa ctgctagaaa aaagcttacc tacggcttgt cagttgaaaa
    38521 tcatcccata tgaatatcag caattaaaag ataagaaaaa cagtgaccca ttattttcca
    38581 tatacgaagt cgtaggaatg attggcacca cagatcctga tatcaccaat atcgactatc
    38641 tttcattaga agacctcatc tcgggggaaa agatgtctgt actagctgaa tggttggaca
    38701 ctactatgaa tgcttcagag aaggaaatat tcaatcagcg catcattcgt aatttttcat
    38761 tggaaaaagt actggattcc gtgactattc tagatacaga gaaggtgatg ggagaaatcg
    38821 atcattttat gagagaatta gaggtgcagt tgaatcgaag catcagcaat cccaaaaaat
    38881 tagcgttgta tgtccatgtg agctgtctca ttgaacgatt gatccgacaa atgccaatcg
    38941 aaacctatca aggattagag aaatggaagc agtgtcaaaa agaagggtta tctgctatta
    39001 aatctgcgtt tagtgtcatt gaagagcatt atagtgtcat gatccccaat tctgagattg
    39061 cctatatcta tgatattttg agtgaagata cagagtttct ctcgatagaa gaagaatttt
    39121 gaacataagc aagttgttgc cactaatttt ggcatgcaac ttgctttttt agtatgtgta
    39181 agtgaaaaga ggagatgaaa aagtggatag agaaattatc ttagcttccc atggaaaatt
    39241 tgcttcaggg atattagatt cattagagct gatctatggg aaaaatcatt ctattactgt
    39301 attcgattgc tatactgatg agaattttga tttagcggaa acagtaaggc agctttttat
    39361 gaggtacaaa gataaagaaa tcattgttct gacggatctt tttggcggaa gtgtcaacaa
    39421 cgaattctta caatatatca atcgggatca tgtctatctc gttgccggat tgaatttgcc
    39481 actattgatt gagctagtat ctcggttgga cgctgaagta gagacaactg ttttgatcca
    39541 gcaggtgcta actgattcaa aaaaaatgat ccagttttgt aacgagcggc tcaatcagaa
    39601 aatagaagaa gacgaatttt aggaggaaga aaaatgattg tattgacaag agtcgaccat
    39661 cggttattac acggacaagt agctttttca tggacacaaa caataggcgc agactgtatt
    39721 ttgattgcta atgatgatgt acctacgaat gagatacgaa agacaacgat caaattagcc
    39781 aagccacaag gagtcaaact agtgatcaaa tcaattgatg actcgattgc cgcgttgaaa
    39841 agcggggtga cagataaata taagttattc atcgtagtgg aatcgatcga ggatgcatat
    39901 aagctggcag aagcgtatcc agaaatcaaa accatcaact taggagggat caaggcaaaa
    39961 cctggtactc gcagcatcgg aaaagcggta aatattttac cagaagagga ggaacgcttg
    40021 aaacgattaa ttgacaaaca aatagaagta gaaatccgtc aagtaccagc agataaaaaa
    40081 gtggatgtaa gagaagtttt gtaagaaagg aagaacctca atgattgtac aagcagtctt
    40141 attaggaatt gttgcatttg tcgcacaatc agaatatgca ctagggacat cgttgctttc
    40201 tcgtccgatt gtgacggggc tgtttacagg aatcgtgtta ggtgatgtaa aaactgggat
    40261 cattatgggc gcaactttag agttagcatt tatcggatcg ttctcagtag gtgcttcgat
    40321 tccacctgat gttgtgaccg gtgggatttt agggacggct tttgctatta cagctggagc
    40381 cggtacagaa accgcgcttt tactaggttt gccgattgct acgttgacat tgatattgaa
    40441 aaatatttac ttagggcttt tgattccaat tatgaaccat aaagcagaca attatgcaga
    40501 agaaggaaat tataaaggag tcgagcatat gcacttgctt gccggtatcg gtctttcctt
    40561 gatgcttggt gttgtggtaa tggtttctta tatggtggga agcaatacga tcggaaatct
    40621 attaaatatg attcctgact tcgttcaaaa ggggttgtca gtagctacag ggttgattcc
    40681 agctcttggt tttgcgatgc ttgctcgttt gctgatcaac aaacaagttg caccatattt
    40741 tttcttaggt tttgctatag cttcttactt agagattcct gtgaccggag tagctatttt
    40801 tggtgcgatt ttagcagttg tggtagtcaa tattatgaat gtccgtcaac taccacttca
    40861 aacaactgca ggggaggtag aagaagatga agaattctga gatcaaaaac agcaaaataa
    40921 cgaaaaaaga gctaaatcac gtattttggc gttcttttca aatggagttt tcttggaatt
    40981 atgaacgtca gatgaatatg gcttatgttt atgcaatgat tccgattttg aaaaagttat
    41041 atcagtcgaa agaagaaatg gcagcagctt tgaaacggca tctagagttt tttaacacga
    41101 ccccacatat cgttacactg attttaggaa tcacggctgc aatggaggaa gaaaataagg
    41161 atgatcctga atttgatgtg actgcgatcg atagtatcaa aacatctttg atgggacctc
    41221 ttgcagggtt aggagattct ttcttttggg gaactttgcg attgattgcc acaggtgtgg
    41281 gtacctcttt agccatgcaa ggaaatattt taggccctat cttgttcatt ttgattttca
    41341 atattccgca cattctgttt cgctatctag caacaggttg gggatatcgc ttaggaacgg
    41401 gttttttgaa aaagatccag gcaaacggta tgatggaaag tttgacatta ggcgcgtcta
    41461 ttattggact gatggtcgtt ggagcaatga ctgccacgat gatcaccatc aatattcctt
    41521 taaaaatcgg ttcaggagaa aatgctgtga ctgttcaaag tatttttgat gatatcgttc
    41581 caaatatctt atgtcttgga gcatttggca tagtgtttta tctattgaag aaagaagtga
    41641 aaccattaac gatcttgatc ggactagctt tctttggaat ttttggttcg tggataggga
    41701 ttttttaaaa aaggagcaga gaaaatgttt acgatgcaag attatatcta tgaagaaaag
    41761 gaagtactaa gtacgatctt gaaaaagaat gatttttcga caagagaaca tatgaaaaaa
    41821 acagtgaatt tactgatctt agcaacgggt tcatcttata acgcttgttt agcagcgaag
    41881 ccagcattgg aatcttatgg tgatcttact gtcgatattc aagaaccttt ttattttttc
    41941 aattatggaa aactttctcc ttcaatcgat actgtgattg ctgtgtcaca aagcgggaaa
    42001 agtgcttcta ctgttgaagc agtaaaaatg atacaaaaac aagggttacc tgttgttgct
    42061 atcacaaatg acgtgcaaag tccacttgct ttagaagctg cacaaattat tgatttaggt
    42121 gccggggtag aatcagtagg cttcgttaca aaaggctatt ctgcgactgt tttacagtta
    42181 ctactcttag ggataggaat tggaataagt aaaaataaaa tcagcaaaaa aatagaacaa
    42241 gactacatgc aacagttgcg caaaataatc aaccatttac cagcgattat tcaaaaaacg
    42301 gaagaatttt ttgatggata tcaaagttta tttcgtttag cacagcgttt cgtcaccatt
    42361 ggatatggtc caaactgggg aacagctaaa gaagcagaga cgaaattgac tgaaacaatc
    42421 cgcgttccgt cacaaggatt tgagttagaa gcttatatgc acggcccata cctggaggca
    42481 gatgcttcgc atttgctatt ctttattgaa ggggaaagtg taaataagga acgttcgcaa
    42541 aagttgcaaa gatatatgag tcggtacgtt ggagagactc tcaccattac cacaaaaaaa
    42601 gcaagaaacg agaaaacact tggattagca atagaatgtg atgaatatct gtctgtatta
    42661 gcgcttgtcg ttccgtttca actattcgct tataaaaccg cagtagctaa aggtattgac
    42721 ttgaacaaaa agatttttga agactttgat acagtcttga aaagtaaatt ataagaggtg
    42781 gaaatcatgc tgaaattcaa tgaagaagaa caaatcaaag caataaaagg cgcactagct
    42841 ttacgtccgc aagtagaaga aatcatcgat aaactttatg cggaaaaatt tgacgctgtc
    42901 tattatctag gaatcggtgg aacgtatgct tcctcgatgc aagctgtcac ttatatgaat
    42961 gggaaaagca acttgcctgt ctttgtacag catgctgcag aatattacac tactggaaac
    43021 aaaagattaa caaaagattc tatcgttatt ttgtcctctg ttaccggtac aactcaagaa
    43081 gtagtgaaag cagtagaaca aatcaagaaa gtaggagcga cactgattgg atttatcgat
    43141 aaagcgaaca gtaagttgtc tcagctatgc gattttgtgg tcacttatcc agctcctgga
    43201 acagaacaaa tcaaattttt tatggcagca gatcgattga tgtatttgaa tggagaattc
    43261 gaagcttatt cagaatacta tgaacagctc gaacgttatt taccaacagg gttagtggaa
    43321 gcagagaaaa aagcagatgc atttggctta tcatttgcag aaaaacatcg acgtgatagt
    43381 atgcattatt ttattggagc agggaatcaa tggggagctg tttattcata tgccatgtgt
    43441 tactgggaag aacaaagctg gcttccatcg aaatctatcc atgctgccga gtttcttcac
    43501 gggacgttag agatcgtaga agaaacaacc ccagtcacat tatttttagg cgaagatgaa
    43561 cagagagtgt tatctgaacg tgtggctaaa cttttgccaa aaatttgcag caattataca
    43621 ttgatagaca caaaagacta tccagtagaa ggtatcagtg aaaaatatcg cggacgtgtt
    43681 ttgtctttct tattgatgca tgtagtgaca caacgcatcg atgctcatgt ggagcagttg
    43741 aactgccatc cattagagat acgccgctac tatcgtcagt ttgattatta ggatagactg
    43801 gataaaaaga atataaaaaa taaagagagc agcgataact gctcccttta tttttttaaa
    43861 atattggcat caattacgtt ataaaacaca ttttttgcat tatctacagt tcaacttata
    43921 atctgtttaa tgggacatgt gggtgccaac cattttttgt tatgcaatag tactatttag
    43981 ttgttgcatg gatccgtagt aaaagtccaa gtacaacgag ttgcgccagt ttacatagcg
    44041 ttttgtatcc agaatgttga ctaaaacaaa agttcctatg tcaaccgtca acagagacaa
    44101 tctgtccgtt gcaggacctg acagatttag aaatgttcaa tctgtctctt atgtatttta
    44161 aatcaatact cactaggaga agtttcctaa cctcctaata gtaatgctgg tagtaacatt
    44221 gtcaaaactg cttcctctta ggaacaagca aagcataacg agtgtaaaaa taaaatgtag
    44281 actattgtaa catatcattg attatttcaa gtaaaaacga taaaagaagt aaacaaacac
    44341 ttaaaaacaa tggaaattag tcccaacttt aagaaatgta tactataatg gaaattatca
    44401 attatttatt tggaggaata tccatgaaac aaaaaatcgc agttcttggt cctggatctt
    44461 ggggcactgc tttagcacaa acattggcag aaaacgggca tgatgtccgt atttggggaa
    44521 atgtacctga acagattgat gaaatcaata agtatcatac aaatcagcat tttttacctg
    44581 atttgacgat cccagaatcg attatcggat ataaagaatt ggcagaagca gtggataacg
    44641 cagatgctat tttatttgtt gttccaacaa aagcgattcg ttcagtcgca caggaactta
    44701 ttggtaaaat gaatactaag ccaatcatta tacatgcaag taaaggacta gaacaagata
    44761 cgcataaacg aatctcagaa gttttggctg aagaaattcc agaagaaaaa agacaggcaa
    44821 ttgttgtatt atctggtcct agccatgctg aggaagtggc agtacatgat atcacaacaa
    44881 ttacagctgc aagtattgat caaaaagcag cagcctatgt acaaaaactg ttcatgaatg
    44941 attatttcag gatttataca aataatgatg tgattggcgt agaaactggt gcagcactga
    45001 aaaatatcat tgcaattggt gccggcgcta tccatggatt aggattcgga gatgatgcaa
    45061 aagcagcaat catgactcga ggattggcag aaatcagccg tcttggtgtc gcgatgggtg
    45121 ccaatcctct gacatttatc ggtttgagtg gtgtggggga cttgatcgtt acttgtacaa
    45181 gtgttcattc tcgcaattgg cgtgccggta acttgttagg acagggacat aagctggaag
    45241 aagttctaga aaacatggga atggtcgttg agggtgtggc aacgacaaaa gcagcagtag
    45301 agctagctca acagctaggt gttgagatgc caattactca aacaatctat aatgttttgt
    45361 ataatggaga agatatcaaa aaagcagcaa aagaaatcat gttacgtgac ggaaaaatgg
    45421 agaatgaatt ttctcttcgt taaatagatg atcaatagtt aatcgtcgtt taggaggaac
    45481 agcaagtgaa ggtcaaaaaa gcagtcattc ctgccgctgg gctaggaaca cgttttttgc
    45541 cggcaacaaa agccatggca aaagaaatgc ttccaatcgt ggataaacca acgatccagt
    45601 ttattgtgga agaagcattg gattcgggaa tcgaagacat cttgatcgta acgggaaaag
    45661 aaaaaagacc cattgaagat cactttgatg caaatatcga attggaaaac aatttgcggg
    45721 aaaaggaaaa aacagaatta ctcgctttag ttgaagaaac gactcaagtc aatcttcact
    45781 tcatccgtca atctcatcca agaggactgg gggatgccgt gcttcaagca aaagcattta
    45841 taggaaatga accgtttgtc gtcatgctgg gggatgattt gatgaaagat gatatcccat
    45901 tgactcaaca attgatgatg gattatgaag aaacacaagc ttccgctgtt gccgtcatgc
    45961 gtgtaccaga aaatgaaaca tctaaatacg gaattattga tcctaaaaca gatagcgaaa
    46021 agggtcgttg cagagtaaaa gggtttgtag aaaaacctga aatgggaaaa gcaccaagta
    46081 atttagccat tatcggacgt tatctactga ctcctaaaat atttgagata ttagaaactc
    46141 aagaaccagg agcaggaaac gagatacagc taacggatgc acttcagact cttaaccaga
    46201 cagaggcggt ctatgcgaga gagtttaaag gaaaaagata cgacgtaggc gataagttag
    46261 gatatatgaa gacaaatatt gaatatggac ttcaacattc ggaaattggg acttcattaa
    46321 gtgcatatat tatccagttg agtaaaaagc taagaacaga aagttaactg gaaataagtg
    46381 gcctgctgag aatgaaaggc tatttgttat taaagcggca gcttgtgcgt catttgcgca
    46441 actgtcgttt tagttttttg actctagatc agttgagtcg tggaaaacga aagatagaaa
    46501 aagactttcg tgaatagatt cagaaaatat tatgctaatg gtttaatttt tttttaagtt
    46561 gtataaaaga aaatgattac ataagagaaa tgaaagccaa gccagaagat tcatagtaga
    46621 ataaaaaggc gaatttttta attataaaaa aaggtgtgtg ttcactatgg gaaaattagt
    46681 cgctgttgca cagtcgctgc ttgatatact caagtggctg atggaaggaa gcaattggat
    46741 atttgtgttg ccactattgc ttattagtct atttatcatg tttcgcatgg tcagaaaaaa
    46801 agaaacgttt ctgattttta tctggtatgc agcatccgtt ggggttgcta ccttgatggt
    46861 tgaattggcg ttaggtagtt gggaagcttg cgtatttgct ttattttttg ctgtactgta
    46921 tctaatcatt tatatcccat atatgaaaag aaagtctcgg ataggcagaa aaggtagaca
    46981 tacaactact ttttctagta cagattctct cgaacaaagt agaagaacga gaagaagacg
    47041 gtaatattta gtaggtatac gcaaaaaaag ataaaataat ggataaacta ttgagatgag
    47101 agatttattt aattggtgga aaaaagcttt tttcacttat ataaaagaat cttttttaaa
    47161 ggaatgcttg ttgtatcggg ataagccatt ccttttttta tgttatttat atatatataa
    47221 atcataccaa tgtttttttg tattttcttg cttgcacttg gataagagat tacttacaat
    47281 aaattcagat agaaacagct gaataaaaaa aggctccctg acccttagtt ggcgctaaga
    47341 atcagggaat gaccagtcac acacatacac cctgaccgat cattttgcca tagtcaatgc
    47401 agtgcatcga cctaatttat tgtacctaat ctagggtgaa aattctaccc ctatgtagat
    47461 attttccatg gtctgcacgt tgttttattt gctatgtcaa ggtattgggc gtattcgttc
    47521 aatgcctttt ttgtgtttga aacagcaaag accacatgtg ttactgtcta actactgttt
    47581 ttttatgtac ttccttagat taggcagctg tttctattca tgtcaagtat agctaggcgg
    47641 gagagataaa tgagtttatg ttattttgac tattatcacc aattggaaga gaaattaagg
    47701 atagaagagc cgctgatgct tcaagctggc acttggatcg cgaaacaaat taatcaaggt
    47761 ggtagattgc agatatatgc tagccgcaca ctaagtggtg tagcatttga attttgggat
    47821 caaaccccgg atcttgtacc aagtatattg attgaaaatc cagccggagg tgtctatgaa
    47881 acgctagaag gtgcaggaca ggcaattatt gatcagcttt ctgtcaaatc agaagacatt
    47941 tttcttcttc tttcgaatga aggaagaaac ccggcaatca tcgaactagc tcagtggatc
    48001 aaagaaaatg gtcatccatt aatcattgtt actggatttg atttgtcacg aagtatcaaa
    48061 tcgcaacata gcagtggttt gcgattattt gaatttgctg atttggtttt ggacaaccac
    48121 gccaatttac atgatgcagt cttgactttg ccaaatctag atccagcgat ctgcggaaca
    48181 gcctctcttg caacgatctt tttgctgcag caagttttgt attttacagc aaaacagcta
    48241 gtccaggaca caagtggaaa atagttatcc acatgttgac aaagttcctt aaaaaaataa
    48301 tgttccacat aaaaatggag cgtttgaaaa aaagaaaacg attattaatg aggattaaca
    48361 acgactactt tttttgtttt agttatttta agatggatca tctttgattt taagcttgtt
    48421 ttgtttaaag tttgttattt ttataagttg tttcacagtt atgagaaatg agttataaga
    48481 atatgtagtg tcagaaaaat aaaaagtagt ggaaaaagag acaagaaaga atccatatgg
    48541 attctttctt gtctcttaat acacgttgat gaaagagtct tccccaaaac tctttacaaa
    48601 gtaattatag tacatttgtt atcattattg caatgaagtt tacctgatat aacaaaattg
    48661 tccaacagga tacctttttc taatagaaat aaaatacaca aaaattgaag gatagataat
    48721 ggatatttat aagtgtttat tatttttttt gcaatgaaat tcaatttttc aatgattgta
    48781 aaatgaaaaa aacaggacga gattttctct aatctaaaaa taaaaaaaga attttaagga
    48841 aaaacagaga aataaaatac ttaatataaa tggaaagaga aaaaaataat catacatagg
    48901 agaaaaaaaa caaaatagaa aaaagtgatt ttctaataaa ttattcatgt ggaaatgtca
    48961 tttttactgt ataattcatt tgattatcca ttttttattc atcaaaatta ctgaaaaaag
    49021 aaaggaagaa ataaatttga agaaaacaaa ttcttcagga aaaccgaaac gcgacttcac
    49081 taaattatcg acaccccata cgtatgtcat tatttttggt gtagtcatct ttgcatggat
    49141 actgactttt gtcgttccag caggaaagtt cagcacgcaa gatattgaat acaaagatgc
    49201 aaatggcgaa acaagtactc gtactgtttt acgtcaagat tccttccgtt atgcttacga
    49261 gctggataag tcgtatgtgt ttgatcaatt agaagaactg caagatcatc cagcagaacg
    49321 tgaaaaactg gatgttccgg aaaaaggatt ggaaaaagtc attgctgacg gagaaaaaaa
    49381 tcttacgcag gaaaaactag atgaaatctc cttgacagat gatgtgcttt acgatcagta
    49441 cggcgaaaat atctatgata cttctaaaaa attgcataaa acagccaaaa tatggggaac
    49501 agatgatttt ggcggctttg gtttcttaaa ttttgttttt gaaggactag tatctggaga
    49561 taagtatgga tctgctgtag ggatcgctgc attgatcctt gttgttggag gtgcttttgg
    49621 tattattatg cgtaccggag cgatcgacgc aggtatctat gcgtttatca gtaaaactaa
    49681 gggactggag cgtttagctt taccgctatt attctttgct ttttcattcg gtggcgctac
    49741 attcgggatg gcagaagagg taattccatt ctcaatggtg atggttccat ttgtcattgc
    49801 gttaggatat gactcgatcg tagcagtaac cgtgacttat gtcgcatctc aagtcggaaa
    49861 tgcgacctct tggatgagcc cgtttagcgt agcggtggct caagggattg ctggaatccc
    49921 cgtgttgtct ggtgcgacat tccgattgat tatgtgggta gttgttactg cattagccgc
    49981 tggttatatg atgatatatg cagaaaaaat ccgtaaaaaa ccagaaagtt cgttgactta
    50041 caaatcagat gattatttcc gttctcatat caaaaagaca tctgatgaaa ataaaaaatt
    50101 catgcttggg cataaattga tcttattaga gatgttagtt gtccttgtct ggatcgtttg
    50161 gggcgtgact caaaaaggct attacattcc agaaatcgct tctcaattct ttgtgatggg
    50221 attagttgct ggaatcattg ctgttctttt caaattagat ggaatgaaag tcaatgacat
    50281 cgcttcttct ttccaatctg gtgcagctga tttagctggt acagcaatcg tagtaggtat
    50341 ggccaaaggg attcttcttg tcttgggagg atctgatgca tctgttcctt cagctttgaa
    50401 tacgattttg catgggatcg ggacggcgtt gaccggtgtt ccagctgtca ttggtgcttg
    50461 ggcgatgtac atcttccaaa gtttgttcaa cttggttgtt acatcaaatt caggacaagc
    50521 agctttgact atgccaatca tggctccact ggcagattta gtaggtgtat ccagacaagt
    50581 agcagttctt gcttatcagc ttggttcagg ttttatggac gcttttacac ccgtatcagc
    50641 cagcttgatt ggtgtgctag gtgttgcacg gatcgaatgg gcaaaatggg caagattcca
    50701 aatcaagatg caaggattcc tgtttgtttt aggaactatt ttcatcatga ttgccattgc
    50761 aataggtctg cagtagtact ggagacctgt aaataaaaaa gtaatccaaa cagtagataa
    50821 ggactccaag aaccgtcatt ttacggtaaa atcaaaggag taaagatcct atcgtttgga
    50881 ttatttttta agatcctatc atcagttata cttaaagaaa gaggaaaaat gtatgaaaat
    50941 cattcgacaa attgaagtgt ttgcaccaga ttacttagga aaaatggatg tactgattgc
    51001 cggtgggaag attttggctg tagaagaaca gctagaaggc ggctacgaag gagtggaagt
    51061 agaagaactt tcaggtgagg gaaaagtact aaccccgggt ttcattgact gtcatttcca
    51121 tattttaggt ggaggaggag aaggcggtta tcaaaatcga acgccagaag tcacattgag
    51181 ccaattgact acagctggtg taacgacagt tgtcggttgt ttgggaacag acggagaagg
    51241 tagagatatg actgcgttga tcagcaaagc gaaaggtctg gaagcagaag gaatctccac
    51301 ttatgtatac gaaggttcgt accgattgcc ggtaaaaaca gtaacagatt ctatcatcaa
    51361 agactttttg acaattgata aaattatcgg aatcggagaa atcgcagtat ccgatcaccg
    51421 ttcttctcag ccaagttttg aagagttcgc tcgtgcagta gcagatgctc gtgtaggagg
    51481 catgttatcc ggaaaagctg ggatcatcaa tgtccactta ggcggaggaa aaagaaagct
    51541 agagctattg acacgaatcg tagaagaaac agaaattccg atcacacaat ttttgcctac
    51601 tcatgcaaat cgcacaccag aattatttga agcttgcgtg gcatttgcca aacgtggtgg
    51661 cacgattgac ttcactgcta gcgaagatcc tgatttttgg gagaagacag atggtgaagt
    51721 tcgcttcagc aaagcactga aacgattgat cgaggaagat gtttctttag ataatttcac
    51781 gatgacctca gatggacaag gaagcttgcc ttattttgat gaaaacaatc atttcctagg
    51841 gttaggagta ggaagtgcca aggcattgct agtagggatc aaagaagctg tgcaaaaaga
    51901 aagtatccct ttggaaatcg ccttacgagc tataaccagt aatccagcac gtatattgaa
    51961 attggataaa aaaggaaaaa tcgaaattgg tgctgatgca gatctgtgta tcttggataa
    52021 agaaacgctt gatattgata cagttatcgc taaaggagaa ataatggtcc aagaaaaaga
    52081 agtcaaagta tgggggactt tcgaaaaaag tttttaatca acagctctaa ctatcttttt
    52141 tagaaaacga gcgttctgtt tgtctgtatc tgttgttgat gttaccctga aggtagatca
    52201 ataaacaaac taagaggagg aagcacaatg gcagatttaa aaggacgttc taaagatatg
    52261 aaagataaag tagtcggtga aggaaaagaa gcatacggca aagcaacaga cgacaagagc
    52321 aaagaaacag aagggaaagc acaatcacta ggtgctgaca tcaaagaaaa agctcgaaat
    52381 ttaggcgacg aagtcaaaga caagttttct cgaaaagacg aaaaaaaata aaaaccactt
    52441 attactaatt gaatcaagca aataaaaaat ccgaaccata tctgcgagac agatatggtt
    52501 cggatttttt atttgatcat tatcctgttt tttaaacttc gattttttga aattttttat
    52561 tttttagttc aaagacttca tcacagcttt ttgctacttc aatctcatga gtcacgatga
    52621 taatacagcg attttgttca tgggcgattt cttggaaaag tttgacgata tcttgtgaag
    52681 ttgtttcatc tagatttcca gtaggctcat ccgctacgat tagttgatgt tcacagcaga
    52741 tagcacgaac gatagcgact cgctgctgct gacctcccga aagtttggtc acctgttttt
    52801 ttgctaatat ttcatcaatt cctacacgag ccagtcgatc taaagcaact tgtcgataat
    52861 tctcttgctt ggtcttagtg atttccattg ctgctatgac gttgtctaga gccgataaat
    52921 aaggaagcaa gttgtaagct tggaaaataa tcgagacatc atttttacga taacttctta
    52981 acccgatttt gttcagtgaa cgatcttgat agtatacctt tccttctttt ggtgcatcta
    53041 gtccagaaat aagcgaaaga aaagtcgttt ttccagaacc acttgctcct aaaatagcgt
    53101 acatttttcc agcttcgaaa ttcagttcta catctttata aagcgcatct tgcggatctt
    53161 gataccaaaa tcccaattgt tctgtccgta acatcaaatt cctcctttag tttaatagga
    53221 tttttcttgg gtttaatctt aatatcccta tagaagctaa aaagacagaa aacagactga
    53281 ttccaaatgc tactccggct aatagtccca attgtgcagg tttgacattg atttccaatt
    53341 cgctgacttg atcagaaaca gcaaatggat tattcgtggt tccttgttga ccatcgcgtt
    53401 gaccgccttg ttcttgtctg ttacctggca tttgtccacc gccaggagct tgctggtttt
    53461 gtgtcgtggt ttctgtctgt tggtcaagta gctgctgtcc cacggcattc gcgacgacgt
    53521 ttccgctaag cgaagcaact cctaatgcaa gaatcataca aatagccact tcggtaaaca
    53581 attggagaat gattttactt ctggattctc ctaaagatag caagacgcct aactcatgcc
    53641 gacgctcccg aatggtaatc ataatgatca gagtaagtat gataataccg gctacagcca
    53701 ctagtaaaac aacattttta gaaaaacttg ccacgttgtt taaaggttcc aacattgact
    53761 gatacatgga atcatttgat tgtaagctaa atgtatctgt gtcgatcagc ttctcagctt
    53821 ctttgagaaa ctcatccatt ttatctggat cagatagagt gtaaatagca gaatctatcg
    53881 tgttatcgtc agatgtccca tttagttcat ttgcaaaagt gtaagaagtg taaagtgtat
    53941 tcgacggatt catgaagttg aatttcatac ccatactgcc gcttgtttct ctggattcat
    54001 aaattccttt gatcgtcatt tcataagtgg tatcttcatc ttcagtactc gtgattgtga
    54061 aagtatctcc gactgccagg tcatttgttt ctgctagagt agaatcaatg actacattgt
    54121 ttgtgccttt gtcgctgtca tctattcctt caccatccgt gatttttgct gttccatcag
    54181 aaaaattact attttgtgca gttgctgaca caccactgat ttgaaagtct gcttgagtca
    54241 tttgcggatt cccgcccatt cctccagcag gttcaccgcc tgcatcagta gtttctgaac
    54301 tgtcttcact tgaatcagaa ctagtgatgg cagttattcc atcttttgcc atagctgagg
    54361 cggaactttc aaaggaataa ctctttacat tatctaattc agctattttt tccgcgtccg
    54421 ttaaggaaac tggtgtaaga gaaaaactgc ctggatctgg acgttcttca gtggtagaac
    54481 cgcttgaaga agtttgttcc tgttttttaa atgaagcttc tcgattggca cttaaagtca
    54541 ctgttgctcc aacttctttt tgtgcttgat tcgctgcttc ttctgcagcg cttcgaatcg
    54601 tgaggccagc tagcacaaaa ataagaatgg ctgtgaacac ggcaaacaat aacaatgaac
    54661 gtccccattt tacttttgta cttttccatg cacgtttcat aaaattcata ttttgcatcc
    54721 ctcctagtag atgcatttga taatagacaa cctatcttaa agctagctta aatcttatgc
    54781 tgtttgcaca ccatcaacat gaggttctgt atatataaaa agtcactata gttattgcaa
    54841 aaaatgtggt aaaatgaaaa aagtatgttt caaaccgacg aagaagaaat gaaagaggaa
    54901 tagcaaaaga aatcctagat gctacagagg gatttttacg tgcatagttg ttctaacaat
    54961 tgctgatact agcgatttag tttatttgtt gtataataat ggggaacagc tgaatactta
    55021 tataagtatt ctggctatag cgtttcgcaa aagatccatt ttgttaatga agtatatcca
    55081 aaataaaatg cccatccaac tgtcagaacg cggatgtgct ggtaattttc ctgctgattc
    55141 tccataagtt gagaaatagt gattttgcat atgcttcatt ggaatggctc atatatttag
    55201 ataaagaaga aaatcgacat ctttaaactt ggatgtcata agaagaggtg aagtttgtga
    55261 gtaccattaa aattatccca ttaggcggcg ttcgtgaaaa tggaaaaaac atgtatgtcg
    55321 cagaagtggg cgaggatatt tttattttag attgtgggct aaaatatcct gaaaatgagt
    55381 tgttggggat cgacgtcgta atccctgatt ttacgtattt agaagaaaac attgatcgtg
    55441 tagctggtgt ctttttaaca catggacatg cagatgcgat cggggcactt ccttacttgt
    55501 tgtcaaaaat ttctgtacca gtattcggga cagagttgac gatcgagtta gcaaaattga
    55561 atgtcagtcg taatgaagca gccaaaggat ttaaggattt ccatgtggta gatgagcata
    55621 cagaaataga ctttggtgaa acagtagtga gctttttccg taccactcat acgataccag
    55681 attcagtggg gatcaatctg aaaacaaaag aaggtagtat cgtttatacg ggagatttta
    55741 aatttgacca aacggctatc ccaatgtatc aaacagatta tgcacgattg gcggaaatcg
    55801 gcaaagaagg agtcttagcc ttactaagtg aatcggcaaa tgcagaaaat cctcagcctg
    55861 tagcttctga agcccaaata gcagatgaag tatttgatac gatcaaatat tgggaagggc
    55921 gtatcatcgt cgcttgtgta gcaagtaatt tgcaacgagt gcaacaagta ttggatgcag
    55981 cagaaaaagc acaacgaaaa gttgtcttga ctggtcaaga tttcgaacga attattcgca
    56041 cagcgatgcg tttagaaaaa cttcaattac caagtgaaga tctgcttgtt acgttgaaag
    56101 acatgaaaaa ctatgatcca gaagaactga tcattttaga aactggccga atgggtgaac
    56161 ccatcaagtc tctgcaaaaa atggcaaacg gtacacaccg taatgtcaag attgaagaag
    56221 gagatttggt ttatatcact actacgccaa gcatcgcgat ggaaaccatc gtggcgaaaa
    56281 cggaagatat catttatcga gctggtggaa cagtgaagtt gatctctgag aatatgcgcg
    56341 tttctggcca tgccaatcct aatgacttgc aattaatgat caatttgatg aaaccaacat
    56401 attttgtgcc agttcaagga gagtatcgtg aattagctgc tcatgcagat ttggctcatg
    56461 cagtagggat gccatacaaa aatatctata ttactggacg cggagacgtg ctggaatata
    56521 agaacaagcg tatgagtgtt gcaggaacta caagtgcaga aaatgtaatg attgatggat
    56581 taggcatagg tgatatcgga aacattgttt tacgtgatcg aaaaatcttg tcagaagacg
    56641 ggattttcgt agcggttgtc actatcagtc ggcgagaaaa gaaaatcatt tcaaaacctc
    56701 aaattacttc acggggattc gtttacgtaa aagctagccg tgatctgatg aaagaaagca
    56761 gcaatatgat tgaaacaatc gttgagaaac atttagaaag caatgatttt gagtggagca
    56821 aattaaagca agacatccga gatcaattag gccgttactt atttgaacaa acaaaacgcc
    56881 gcccagtgat cttgccagtc attatggaag ctactcaacg tcgaaataaa aaataaacaa
    56941 aaagagtaag atgaacctct ctatagagtg ctcgtcttgc tctttttttg cgaaaaacaa
    57001 ataatttttg aatacagcat ccctcgcttt ataataaacg atagaataaa gggagtgaat
    57061 caatgatgag tcaaacaaaa gtcgaacgtt atttagaaga acaaaagatc agctatcaac
    57121 cacttgattt tagtcatgtg gtagaagaat ctttcacaga agaactacaa aaaagaggga
    57181 ttgatccagc tttgatatgt aaaactctcg tagtgaaagg aaacaaaact ggggtgatca
    57241 tcgcattgat tcctttgaac gatcacttag attacaaaaa aacgagacaa gtgacgaaag
    57301 atcgtaaagt tggttttcct ggaatggatt ttgtattaat gcatacagga tatccccacg
    57361 gagcaaacac ccctattgga ataaaactcg cacatcctga ttattgtttt ttagcagaca
    57421 gttctttaaa agaaaaagaa gaagtaattg tgtcaagcgg tgaaatcggg agaagccttc
    57481 ggataaaagt agccgattta gaaaagatcg tccatcctat ttacgctgat ttaattagtt
    57541 aagggacgag aagagaagct aagcagagca gagacctcaa acttgagatt atatctgctt
    57601 ggtacttggt gcatcctgta ttatctgtta caattgcttt gtacatactg tactatcaat
    57661 ccaatgaaaa tatatttagc agctatattt tttcattgat gtgcaagtga tgaaatcgtt
    57721 tttaataaaa aagatacaga gaaaacgcga ggtgtaaaat atgaaaatta cgtatcatgg
    57781 acattcctgt ttaacaattg aaatggaaaa tggccaacgc gtgatgattg acccgtttat
    57841 tacaggaaat ccattgacag acttaactgc agaagaagta aagacagatt ggttgctgat
    57901 tactcatggt catagtgacc acataggaga tatgattcct attgcaaaag aaaatcaagc
    57961 cacaattatc agtattgttg agattgctga ttatgcgaac agcagaggag tagattcatt
    58021 cggtatgaat atcggtggaa aacatgcgtt tccattcggc gtggtaaaat tcgtacatgc
    58081 acagcatagt tcaagctatg aagtagacgg tatcgttcag tatatgggcg agcctagcgg
    58141 aattattatt caagcagaag gaaaaacgat ttatcatgca ggggatactg cttatttcag
    58201 tgatctagga ttgcttgcag aagaattcga tattgatgtc gctttcttgc cgattggcga
    58261 taactatacg atggggccag aagatgcagc aaaggctgcg caaacaattc gtgccaagaa
    58321 agtagttcca atccattaca atactttccc tgtcattgaa caagatcccg aatcttttgt
    58381 agagttactg gaagatagtg aaggaaaaat aatgagcgtc tcggaaacgc tggaagtgta
    58441 ggcagaaaat ggcgacaaaa catgatttga ttttagaata tattgaaagt ttacctgttg
    58501 gcaatcgaat ttctgtaaga agcatcgcaa aagaattgaa tgtcagtgaa ggaacagcgt
    58561 accgtgcaat caaagatgca gaaaatgtcg gactagtttc aacaattcaa cgagtaggga
    58621 ccatccgtat cgaacgcaaa ttaaaaaaac atattgaacg tttgacattt ggcgaggtcg
    58681 tcaggatcat tgaaggggac gttttaggcg gggcggcagg attagacaag gtcttgaata
    58741 aattcgtcat cggcgcgatg actaaacatg ccatggaacg ctatattacg ccaggatcac
    58801 taatgatcgt cggcaaccgg gcggaagtcc aaaaattagc attggaagat ggcgccgcag
    58861 tattgatcac aggaggattc aatacgactg ctgagattgc aaagctagct gatgatcttg
    58921 aaatgccgat cttacgcacc tcttatgata catttacagt cgcaaccatg atcaaccgag
    58981 cgttaagcga ccaattgatc aaaaaagata tcatgcttgt cagtgatatc tatatgccag
    59041 ctgaaaagac tcattatttg cagcagacag atacgatttc tgattatcag cgtttgtcag
    59101 aagaaacgca gcattcgcgt tttccagtcg tcaaccgcca tcatcgtttg atggggattg
    59161 ttacggcaaa agatgtttta gggaaatcgc caaaccagat catcgatcgg gtgatgacga
    59221 aagaaccaat cagtgtaaag aaaacaatga gtattgcctc tgttagccat caaatgatct
    59281 gggatgggct agaagtcatg ccggtcgttt ccgatgactt gacattggaa ggcttgatta
    59341 cccggcaaga tgtaatgaaa gcgatgcagc ttgtccagcg acaaccgcag attgcagata
    59401 cgatttcgga tcagatatct ggaaatatcc atacgattga tactgaccgt gaaggaaatc
    59461 gtttggaaaa ccctaagttc aaattcgtag tagcaccaca aatggtcaat ggcgttggaa
    59521 ccatttcttt tggcgtactt agcgaaatca tttctgatgt cgcacaaaaa acaatggtga
    59581 tgaaccaaaa acgaaatatc ttgattgaac aagtgaacct acattatttg cggctgatcc
    59641 aattggaaag cgaattagac attcgtccac gtgtattgga aatcggcaga cgttccgcta
    59701 aactggatat cgaagtgttt attgaaaaca ccatcgtttc caaagcaatc gttgtttgtc
    59761 aagtaatgga acgttcttag aaagcaggag tgaaatgaca gtacagcaag aaatagtaga
    59821 tacaataaaa aaatacgata aaatcattat ccacaggcat ttgcgccctg atcctgatgc
    59881 attaggatca caagtaggat tagccgaact attacgggaa agtttcccag aaaaagaaat
    59941 acgtcaagta ggtgaaacga ttgaagggct tcgcttttta gcagaaatgc aagaagttga
    60001 agatgtcttc taccaaggag cgctagtcat cgtgactgat acagctaatt cacccagaat
    60061 cagtgatcaa agatatcagt tggcagaaaa actgatcaaa atcgaccatc atcccaatga
    60121 tgacccttat ggagatcttg tgtgggtaaa tacaaaagca agtagctgta gtgagatgat
    60181 tgcagaattt gctttgatgt ttcctgaatc tttaaagatg aacgttaagg ctgcacggtt
    60241 actttatgca ggaatcgtcg gagatacagg gcgctttttg tatccctcca cgacgtcccg
    60301 tacattagag attgcttcga tattgagaaa ttatccattt gatgcaagtg ctttgaacag
    60361 agagattgaa caaatgccga tgaaagtcgc taaactttcc ggttatcttt atcaaaatat
    60421 ccaggtggat gaaaatggtg caggaagaat aatccttccg caagaaattc ttgataaata
    60481 tggaatcgat gattcagaga cagcttcgat cgtttcactt cctggagtga ttgacgaagt
    60541 gctggcttgg gggatttttg ttcagcagcc ttcagggtat taccgcgtac gtttacgttc
    60601 taaggggccg atcatcaatg aattggctaa acgccatcat ggaggaggcc atccattagc
    60661 aagtggtgcg aatgcaaaag atttagcaga agtagaggaa atctataaag agatccaaga
    60721 tatatgccaa tcgtataaga gcagaaaaac agaatgatac ttcgttcgaa aacgtgcctt
    60781 ttgtagtaaa aatcacaaat gtatcttttc aagatcttct ttttccgtta caatagtgct
    60841 cactaaagat tttaaaggag aaagaagatg acattaccaa attgcccaga atgtggctca
    60901 gagtacacat atgaagatcg aggcttgttg atttgcccag aatgcgggaa cgaatggaac
    60961 aaagaagaac aagaaactgt catagaagac ggattagtgg tattagatgc aaatggaaac
    61021 cgtctgttag agggcgatag cgtgacagtg attaaagact tgaaagtaaa aggtgcgtca
    61081 ggtgccatta aacaaggaac aaaagtcaag aacatccgtt tagtagaagg cgatcataat
    61141 atcgattgca aggtagaagg atttggaccg atgaaactga aatcggaatt tgtgaaaaag
    61201 aattaaagaa tattcaaggt cttttcacat tcttttccta ctactaatga taaaataaag
    61261 taaacgaaaa ggagtgaaac gaaaatgtat ggttatggaa tgtatggttt tttagatccg
    61321 acatttcttt tggtcattct tggattagtt atttccggaa ttgcgtcagc gtacgtcaat
    61381 agtactttcc gaaaatacga tcaagtgaga agcaaaaaca atgtgactgg tacacaagca
    61441 gcacaatata tattacaaag tcaacagata aataatgtcg gtgttcaaca aattgccgga
    61501 gatctcacag ataactacaa ttcaggtaat aagatgttga gtttgtctca agcaactgca
    61561 cagtctactt cagttgctgc gataggtgta gcagctcatg aatgcggaca tgcggtacaa
    61621 gatgcttcgg gttatgtccc attgaagatt cgtgcagcac ttgttccagc agctaacttt
    61681 ggttcgatga tttcgttccc cttgattatg gtaggtgtat tgcttagctg gaactctacg
    61741 ttaatcaata tcgggatttt cgctttttct ttagcattac ttttccaatt ggtgacatta
    61801 ccagtcgaat ttaacgcgtc tcggcgagca atccaaattt tgagtgaagg cggactactg
    61861 acggaagaag aagtaccgat ggcaagacac gtattatttg cagcagcact gacttatgtt
    61921 gcagcagcgc tttcgacatt cctgcagctg ttgcgcttga tcttattgtt cggcggcaac
    61981 cgaagagatt aaaataaaga agttgtgaaa tcagcgcttt gatctgagct aataccgaga
    62041 gttagctgat tgaataccat ttatttggaa
//
LOCUS       DADLIO010000007        61939 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.007, whole genome shotgun sequence.
ACCESSION   DADLIO010000007 DADLIO010000000
VERSION     DADLIO010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 61939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61939
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.007"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            120..983
                     /locus_tag="JOX41_000562"
     CDS             120..983
                     /locus_tag="JOX41_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAY6448329.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1112..2734)
                     /locus_tag="JOX41_000563"
     CDS             complement(1112..2734)
                     /locus_tag="JOX41_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAY6448330.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            2983..3504
                     /locus_tag="JOX41_000564"
     CDS             2983..3504
                     /locus_tag="JOX41_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448331.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(3690..5420)
                     /gene="spxB"
                     /locus_tag="JOX41_000565"
     CDS             complement(3690..5420)
                     /gene="spxB"
                     /locus_tag="JOX41_000565"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HAY6448332.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5585..6403
                     /locus_tag="JOX41_000566"
     CDS             5585..6403
                     /locus_tag="JOX41_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005232914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HAY6448333.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6506..6703)
                     /locus_tag="JOX41_000567"
     CDS             complement(6506..6703)
                     /locus_tag="JOX41_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448334.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            6872..7450
                     /locus_tag="JOX41_000568"
     CDS             6872..7450
                     /locus_tag="JOX41_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HAY6448335.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            complement(8495..8998)
                     /locus_tag="JOX41_000569"
     CDS             complement(8495..8998)
                     /locus_tag="JOX41_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAY6448336.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            9357..10382
                     /locus_tag="JOX41_000570"
     CDS             9357..10382
                     /locus_tag="JOX41_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAY6448337.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            10705..11583
                     /locus_tag="JOX41_000571"
     CDS             10705..11583
                     /locus_tag="JOX41_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448338.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            12059..12175
                     /locus_tag="JOX41_000572"
     CDS             12059..12175
                     /locus_tag="JOX41_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HAY6448339.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            13103..13441
                     /locus_tag="JOX41_000573"
     CDS             13103..13441
                     /locus_tag="JOX41_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448340.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            13535..13765
                     /locus_tag="JOX41_000574"
     CDS             13535..13765
                     /locus_tag="JOX41_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448341.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            14165..14536
                     /locus_tag="JOX41_000575"
     CDS             14165..14536
                     /locus_tag="JOX41_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HAY6448342.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(14810..15502)
                     /locus_tag="JOX41_000576"
     CDS             complement(14810..15502)
                     /locus_tag="JOX41_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAY6448343.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(15505..16290)
                     /locus_tag="JOX41_000577"
     CDS             complement(15505..16290)
                     /locus_tag="JOX41_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAY6448344.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            16527..17927
                     /gene="lacG"
                     /locus_tag="JOX41_000578"
     CDS             16527..17927
                     /gene="lacG"
                     /locus_tag="JOX41_000578"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HAY6448345.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            17952..18269
                     /locus_tag="JOX41_000579"
     CDS             17952..18269
                     /locus_tag="JOX41_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAY6448346.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            18282..19955
                     /locus_tag="JOX41_000580"
     CDS             18282..19955
                     /locus_tag="JOX41_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAY6448347.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSGMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            19969..21600
                     /locus_tag="JOX41_000581"
     CDS             19969..21600
                     /locus_tag="JOX41_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinogalactan endo-1,4-beta-galactosidase"
                     /protein_id="HAY6448348.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(22091..23656)
                     /gene="guaA"
                     /locus_tag="JOX41_000582"
     CDS             complement(22091..23656)
                     /gene="guaA"
                     /locus_tag="JOX41_000582"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HAY6448349.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(23715..24638)
                     /locus_tag="JOX41_000583"
     CDS             complement(23715..24638)
                     /locus_tag="JOX41_000583"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HAY6448350.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            24834..25439
                     /locus_tag="JOX41_000584"
     CDS             24834..25439
                     /locus_tag="JOX41_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAY6448351.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            25747..26763
                     /locus_tag="JOX41_000585"
     CDS             25747..26763
                     /locus_tag="JOX41_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAY6448352.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            26904..28205
                     /locus_tag="JOX41_000586"
     CDS             26904..28205
                     /locus_tag="JOX41_000586"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HAY6448353.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            28251..28913
                     /gene="deoC"
                     /locus_tag="JOX41_000587"
     CDS             28251..28913
                     /gene="deoC"
                     /locus_tag="JOX41_000587"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HAY6448354.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            28934..29332
                     /locus_tag="JOX41_000588"
     CDS             28934..29332
                     /locus_tag="JOX41_000588"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HAY6448355.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            29398..30480
                     /locus_tag="JOX41_000589"
     CDS             29398..30480
                     /locus_tag="JOX41_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HAY6448356.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            30692..32254
                     /locus_tag="JOX41_000590"
     CDS             30692..32254
                     /locus_tag="JOX41_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6448357.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            32247..33380
                     /locus_tag="JOX41_000591"
     CDS             32247..33380
                     /locus_tag="JOX41_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAY6448358.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            33380..34336
                     /locus_tag="JOX41_000592"
     CDS             33380..34336
                     /locus_tag="JOX41_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAY6448359.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            34435..35601
                     /gene="deoB"
                     /locus_tag="JOX41_000593"
     CDS             34435..35601
                     /gene="deoB"
                     /locus_tag="JOX41_000593"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HAY6448360.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            35625..36443
                     /locus_tag="JOX41_000594"
     CDS             35625..36443
                     /locus_tag="JOX41_000594"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAY6448361.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            36460..37167
                     /gene="deoD"
                     /locus_tag="JOX41_000595"
     CDS             36460..37167
                     /gene="deoD"
                     /locus_tag="JOX41_000595"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAY6448362.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(37465..38151)
                     /gene="gpmA"
                     /locus_tag="JOX41_000596"
     CDS             complement(37465..38151)
                     /gene="gpmA"
                     /locus_tag="JOX41_000596"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HAY6448363.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(38323..38904)
                     /locus_tag="JOX41_000597"
     CDS             complement(38323..38904)
                     /locus_tag="JOX41_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAY6448364.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(39037..39720)
                     /gene="rpiA"
                     /locus_tag="JOX41_000598"
     CDS             complement(39037..39720)
                     /gene="rpiA"
                     /locus_tag="JOX41_000598"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HAY6448365.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            40039..40452
                     /gene="rpsL"
                     /locus_tag="JOX41_000599"
     CDS             40039..40452
                     /gene="rpsL"
                     /locus_tag="JOX41_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007085295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HAY6448366.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            40536..41006
                     /gene="rpsG"
                     /locus_tag="JOX41_000600"
     CDS             40536..41006
                     /gene="rpsG"
                     /locus_tag="JOX41_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HAY6448367.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            41100..43187
                     /gene="fusA"
                     /locus_tag="JOX41_000601"
     CDS             41100..43187
                     /gene="fusA"
                     /locus_tag="JOX41_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HAY6448368.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            43359..44546
                     /gene="tuf"
                     /locus_tag="JOX41_000602"
     CDS             43359..44546
                     /gene="tuf"
                     /locus_tag="JOX41_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAY6448369.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            44953..45261
                     /gene="rpsJ"
                     /locus_tag="JOX41_000603"
     CDS             44953..45261
                     /gene="rpsJ"
                     /locus_tag="JOX41_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HAY6448370.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            45292..45921
                     /gene="rplC"
                     /locus_tag="JOX41_000604"
     CDS             45292..45921
                     /gene="rplC"
                     /locus_tag="JOX41_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HAY6448371.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            45949..46572
                     /gene="rplD"
                     /locus_tag="JOX41_000605"
     CDS             45949..46572
                     /gene="rplD"
                     /locus_tag="JOX41_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HAY6448372.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            46572..46862
                     /gene="rplW"
                     /locus_tag="JOX41_000606"
     CDS             46572..46862
                     /gene="rplW"
                     /locus_tag="JOX41_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HAY6448373.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            46901..47734
                     /gene="rplB"
                     /locus_tag="JOX41_000607"
     CDS             46901..47734
                     /gene="rplB"
                     /locus_tag="JOX41_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010747214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HAY6448374.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            47777..48055
                     /gene="rpsS"
                     /locus_tag="JOX41_000608"
     CDS             47777..48055
                     /gene="rpsS"
                     /locus_tag="JOX41_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HAY6448375.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            48078..48425
                     /gene="rplV"
                     /locus_tag="JOX41_000609"
     CDS             48078..48425
                     /gene="rplV"
                     /locus_tag="JOX41_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HAY6448376.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            48439..49095
                     /gene="rpsC"
                     /locus_tag="JOX41_000610"
     CDS             48439..49095
                     /gene="rpsC"
                     /locus_tag="JOX41_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HAY6448377.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            49098..49532
                     /gene="rplP"
                     /locus_tag="JOX41_000611"
     CDS             49098..49532
                     /gene="rplP"
                     /locus_tag="JOX41_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HAY6448378.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            49522..49710
                     /gene="rpmC"
                     /locus_tag="JOX41_000612"
     CDS             49522..49710
                     /gene="rpmC"
                     /locus_tag="JOX41_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HAY6448379.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            49735..50001
                     /gene="rpsQ"
                     /locus_tag="JOX41_000613"
     CDS             49735..50001
                     /gene="rpsQ"
                     /locus_tag="JOX41_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HAY6448380.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            50059..50427
                     /gene="rplN"
                     /locus_tag="JOX41_000614"
     CDS             50059..50427
                     /gene="rplN"
                     /locus_tag="JOX41_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002460061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HAY6448381.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            50464..50772
                     /gene="rplX"
                     /locus_tag="JOX41_000615"
     CDS             50464..50772
                     /gene="rplX"
                     /locus_tag="JOX41_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HAY6448382.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            50800..51339
                     /gene="rplE"
                     /locus_tag="JOX41_000616"
     CDS             50800..51339
                     /gene="rplE"
                     /locus_tag="JOX41_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HAY6448383.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            51358..51543
                     /locus_tag="JOX41_000617"
     CDS             51358..51543
                     /locus_tag="JOX41_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HAY6448384.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            51579..51977
                     /gene="rpsH"
                     /locus_tag="JOX41_000618"
     CDS             51579..51977
                     /gene="rpsH"
                     /locus_tag="JOX41_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HAY6448385.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            52009..52545
                     /gene="rplF"
                     /locus_tag="JOX41_000619"
     CDS             52009..52545
                     /gene="rplF"
                     /locus_tag="JOX41_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HAY6448386.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            52706..53062
                     /gene="rplR"
                     /locus_tag="JOX41_000620"
     CDS             52706..53062
                     /gene="rplR"
                     /locus_tag="JOX41_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HAY6448387.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            53083..53583
                     /gene="rpsE"
                     /locus_tag="JOX41_000621"
     CDS             53083..53583
                     /gene="rpsE"
                     /locus_tag="JOX41_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HAY6448388.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            53598..53777
                     /gene="rpmD"
                     /locus_tag="JOX41_000622"
     CDS             53598..53777
                     /gene="rpmD"
                     /locus_tag="JOX41_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HAY6448389.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            53821..54261
                     /gene="rplO"
                     /locus_tag="JOX41_000623"
     CDS             53821..54261
                     /gene="rplO"
                     /locus_tag="JOX41_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HAY6448390.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            54261..55556
                     /gene="secY"
                     /locus_tag="JOX41_000624"
     CDS             54261..55556
                     /gene="secY"
                     /locus_tag="JOX41_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HAY6448391.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            55618..56265
                     /locus_tag="JOX41_000625"
     CDS             55618..56265
                     /locus_tag="JOX41_000625"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HAY6448392.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            56456..56674
                     /gene="infA"
                     /locus_tag="JOX41_000626"
     CDS             56456..56674
                     /gene="infA"
                     /locus_tag="JOX41_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HAY6448393.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            56707..56823
                     /gene="rpmJ"
                     /locus_tag="JOX41_000627"
     CDS             56707..56823
                     /gene="rpmJ"
                     /locus_tag="JOX41_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HAY6448394.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            56841..57206
                     /gene="rpsM"
                     /locus_tag="JOX41_000628"
     CDS             56841..57206
                     /gene="rpsM"
                     /locus_tag="JOX41_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HAY6448395.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            57234..57623
                     /gene="rpsK"
                     /locus_tag="JOX41_000629"
     CDS             57234..57623
                     /gene="rpsK"
                     /locus_tag="JOX41_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HAY6448396.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            57703..58641
                     /locus_tag="JOX41_000630"
     CDS             57703..58641
                     /locus_tag="JOX41_000630"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HAY6448397.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            58669..59049
                     /gene="rplQ"
                     /locus_tag="JOX41_000631"
     CDS             58669..59049
                     /gene="rplQ"
                     /locus_tag="JOX41_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HAY6448398.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            59321..60160
                     /locus_tag="JOX41_000632"
     CDS             59321..60160
                     /locus_tag="JOX41_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAY6448399.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            60136..61005
                     /locus_tag="JOX41_000633"
     CDS             60136..61005
                     /locus_tag="JOX41_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAY6448400.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            60995..61792
                     /locus_tag="JOX41_000634"
     CDS             60995..61792
                     /locus_tag="JOX41_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HAY6448401.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
BASE COUNT        19613 a        11075 c        13187 g        18064 t
ORIGIN      
        1 tcacaacctc ttattttgat tagaacttgc gaaaataaac cggttaaagt gtgtctagcg
       61 caagagattt gctataatag acgataaggg taaaatgtaa cgagaagggg ttgaaaaatg
      121 tgtatcaaat tgtaacagat tcttgttgtg atctgccata ccatgtatta gcaaaagaaa
      181 aagttgattt tttatcaatg aatctccaat tgaatgatca agagttagta gatgacctcg
      241 gaaagacatt caattatgac cgctacatga atcagctgaa aaatggtgcg atgcctacga
      301 catcacaaat caatgttggc cgatatttag aatttttccg ttcttatgcg gaaaaacaga
      361 ttcctgtttt atatgtggct ttttccagtg gattaagcgg ctcttacagt agtgcgcttc
      421 aagcggttga attgctgaag gaagaatatg aagaccctga gatctatgtt tttgatacaa
      481 aagctgcaag tattggggaa gggcttttag tattggaagc tgtaagattg aaaaaagaag
      541 gtaaaagcat cgaagaaacc ctagagtggc tggaaagtaa ttatttgaaa gtccattcat
      601 gggtaacagt agacgatctg aaatatctag aacgaggcgg taggatttcc aaagcaagtg
      661 ctactcttgg cagtctattg agtgtaaagc ctattattac ggtggataaa gaaggaaggc
      721 tgacgaatgt tgacaaagtt cgaggaagaa acaagtcgat ccagacaatc gtcaatgaga
      781 cggtaaaaac aatcgttgca ccacttgatc aaatcgttta tgtggcttac gctggggatc
      841 tagagagcgc ggagaaggca aaacggcttt tggaagagca gataaagatg aaagatgtga
      901 agctttatcc cttaggacca acgatcgcca gtcacacagg ctatggctgt atcgcgattt
      961 tttcgatggg aatcagtcga taaaagcagt aactcattct gtaaaaaagc ccagaaattg
     1021 attgtaacaa aaacagcgac tcttaaaaga tagatgagca tcctatctct tagaggtcgc
     1081 tgttttttta ttttttaagc taaataggcc attatgccca taactcgttc aattgttttt
     1141 gaatatctgc attttccaaa aattcatcat atgtcgtatc agctcgatcg atcacacctt
     1201 tatccgaaac ggcaatgatg cggtttgcca atgtttggat aaattgatgg tcatgtgacg
     1261 caaataagat tgagccagta aatgccatca agccgtcatt caatgctgtg attgattcta
     1321 agtctaaatg gttcgttgga tcatctaata caagtacgtt agctttcgaa agcatcattt
     1381 ttgaaagcat gcaacggact ttctctccac cagataaaac attcactggt ttcaatactt
     1441 cttcaccaga aaacaacatt cttcctaaga agcttcttaa gaaggtgtta tcatcttctt
     1501 ctttacttgc atattgacgc aaccagtcta aaatcgttag atcagtatcg aattctttcg
     1561 ttgtatcctt tggtaaataa gaattacttg ttgtcacacc ccaacgtact gttccagtat
     1621 ctggcgtaat ttcacccatg ataactttga atagcgttgt tgttgttata tcattttctg
     1681 cgacgaaagc gaccttgtct tctttgctca aattaaaaga tatatcatct aaaattttct
     1741 ttccatcaat cgttacactt acattttcta cctgcaataa gtcgtttcca atctcacgtt
     1801 caggtttgaa tccaacgaat ggataacgtc tagaagaagg ttggatatcg tctaaagtaa
     1861 ttttttcaag cattttttta cgtgaagttg cttgttttga ttttgatgca ttcgcactaa
     1921 agcgggcaat aaattcttgg agttctttga tttgttcttc ttttttggca tttgcgtttg
     1981 cttgaagttt agccgctagt tgactagatt ccaaccaaaa atcataattt cctacataaa
     2041 gtttgatttt accaaaatct agatccgcca tatgtgtaca tactttgttc aaaaagtgac
     2101 ggtcatggga tacaacgatc acagtatttt caaaattgat caaaaattct tccagccaat
     2161 tgatcgattg gatatccaga ccgtttgttg gttcgtctag caaaagaaca tcaggtttac
     2221 caaatagtgt ttgtgctaat aacactttta ccttttgtcc accagttaat tcactcattt
     2281 gctgatggtg caattcttca gggatgttca gaccttgcag taaaacagct gcttctggtt
     2341 cagcttccca tccattaagc tcagcaaatt ctccttctaa ttcagctgct cgaataccat
     2401 cttcgtcagt gaaatcctct ttcatgtaaa tcgcatcttt ttctttcagc acttcataca
     2461 gacgcttgtg tcccatgatg actgtttcaa gtacagtata gtcttcatag tcgtaatggt
     2521 tctgtttcaa tacggccatc cgttcatctg gtcccatagt aacggaacct gtggaaggct
     2581 gcagatcccc tgataacact ttaaggaacg ttgatttacc tgcaccattt gcaccaatca
     2641 agccatagca gtttccgggg gtaaatttaa tattcacatc atcaaatagt ttgcggtctg
     2701 aaaagtgcaa actcacatca tttacagtaa tcaatttttt tcctcacttt tatcattatt
     2761 agttttgaca agtcttatag aattatatag gggaaaggta aaagattcaa ggcaatcgaa
     2821 cattctttgt gtttcacgtg aaacagaatg aaaaaaataa aaataaaagc ggagcgaaaa
     2881 tagctactat aggatttatt agtttgcaac agcataattt ttgacgttat ttataagagg
     2941 gagtactata aaactgtaaa agaaatgaaa gaaggattga aaatggatga aaaaagaacc
     3001 atcgactggg gctcattgat tttgggaatt ttatttgtac ttgtctcatt gttatcattt
     3061 caagaccctg tcggaaattt agttgcaatt gtagtagtct ttgcgatttt tgcctttatt
     3121 aaagggatat ttgaactgtt tgtacggaac agattaaaag agctaacagg atataaagga
     3181 aagatgccct taataatcgg gatcatcgat attctagttg gcgtcttttt cttattcaat
     3241 attggtgcag gagtcgcagc attgcctttt gtttttgcag tatggtttat tgctgattca
     3301 gttttagcgt tatttactgc tgacttggca agaggagtaa gtgaaggata ttattggttt
     3361 acgatcatcg tcaatatttt aggaatttta ttaggaattt tcttattgtt taatccaatt
     3421 tcttctgcgt tgacattaag ctttttagtt ggattctatt ttatgttatt tggtatcaca
     3481 catatcgtct atgcatttag ataagtaaaa tcaaacaaat aaaaaagccg gcttccgatt
     3541 acagttttac tgttgtaatt ggaagccggc ttttttatca tggacaaata tgcacgaggt
     3601 gatttttagg tgtcgagaca aatttatgca aaaatgtgag aagctatata cacaaatttt
     3661 atcttaatac tcgaagcata gcgcagttgt cacaacctct tttcatataa ttcattcaat
     3721 actggcaaat catggacttc atatttttct ttgaatgctt ggatttcttc ttcagaatat
     3781 tttcttggat ctaaatgcag atcttctact ggcaatgggc gcttgttatt gatcttcaca
     3841 tcgattacta caggacgatc tgattttgca gctgcatcaa aggcaaatcg aagttgcgag
     3901 tattctgtga ctgtaaagct atttgccccg agcgcttctc caactttacc gaaatctgca
     3961 tcttctaaaa atacaccaaa tttcttttgt tccgtatctt cttgttctgc ttcgatgaaa
     4021 ccaaaagaat cattcgaaaa gacaacatta ataattggaa gctgatattt gacttgtgta
     4081 atgatatctt gcatgaccat agcaaacccg ccatcaccac ttaaggtaaa tacttgtttt
     4141 tctgggtagc ttagttgtgc ggcaattcct cctggcacac cattacccat agttgcgaac
     4201 catccagatg tcgtatgttt ttgtttaccg ttcatattca ataaacgaat agaatggata
     4261 gtcgtgttac cgacatctgt gacgaaaatc gcatcgtctt cagcaatacg attgatttct
     4321 ttatagacag cctctggacg aatcggttct tcctctcgat cttcaaaaga tttcaaccaa
     4381 tttacccatt tttctttatt ttcttgattt gctaggtacc agctatcagc agggcgagca
     4441 tcccctaact cgacaagtct ttgcaaagct gtgtttgcat caccgaggat cgacaaagat
     4501 gtttcatggc gtcgtccaaa ttttgacgca tcgatatcga tttggataaa ttcagcagtt
     4561 ggattaaaaa atgcacgtcc aaatgggaag tcgctaccga caaataagat cagatcggct
     4621 tctgccaatg cttcatttcc gggtttagta gcgacacgtc cagcaaaacc aagaaagttt
     4681 tcataatcat caggaataat tccttttgct agaacggaag cgacaacagg aactgaaaaa
     4741 tgttctgaga attctttgat ttgcggaaat ccgtttcgcg ttccttgacc aacataaaga
     4801 actggttttt ttgctttttc aagataaggc aaagcagcta gcaaatcttt ttcttctggt
     4861 aatatcacac ttgttttgtg agtgtgagcg gtggagaaag gttgttcgtc aatttcttca
     4921 aaaccaagat caacagggat agtcacgata gccacgcctt tatgctcata ggcggcttta
     4981 atggcttcat ctactacatg cggaagactt tgtggtgtca tgactgtacg attgtatacg
     5041 ctaacatctg cgaaaatagg attttcattt agttcctgga aagagttata gttcatggat
     5101 gtagaagcaa cttgtcctaa gaacgctact agaggcacat ggtccatctg tgcatcatac
     5161 aaaccattga tcaaatgtgt cgcaccaggt cctgcagagc cgaagacagc gccgactttc
     5221 cccgttaatt ttgcatctgc agcggctgcg agtgcgccga cttcttcatg acgaacttga
     5281 atgtagttga tttcggtttt ttcttgatat agcgcatcca taattgaatt gaaagatcct
     5341 ccgggaatgc cgtaaatatg gtcgataccc cagctttcaa gaacttttac cattgcgatt
     5401 cctgcattga tttttgacat ggtgtttcac tcctttagca atgatgatac ataaattttt
     5461 tgtatctaga gtatagaact ttttatcgaa aatcccaact aattcgtctt ttcacaaaaa
     5521 tgtagtcatg tttttgggaa tatgctagag tagtacatag atagattcaa gagaggggaa
     5581 tggcatggtt gaatggctat tgagacttga accttggcag caagcacttg ctgggacagc
     5641 ttttacttat tttatgacag ctcttggtgc cgggttggtt tttttcttta aagaaatcaa
     5701 aaaagaagtg ctaaacttga tgttaggatt tgcttctggt gtcatgattg ctgcaagttt
     5761 ttggtctttg ttagatccgg ctattacaaa agcagaagaa aatggagata ttgcttggct
     5821 agttgtaagt attgggtttg gtttaggcgg tgtgttttta tatatggcag ataaaacact
     5881 gccccatatg cattttggac cacaacatga agcagaagga ttgcctaccc atttaaaacg
     5941 gacgatcttg cttgtttttt ctattacatt gcataacatt cctgaaggtt tagccgtggg
     6001 ggtagcattc ggtgcagcag caactgcgga taatccgaca gccgctatat tagccgctgt
     6061 ttcggtggcg ctaggtattg gtatccaaaa cttcccagaa ggagcagctg tatcaatccc
     6121 gttgcgacaa gaaggtctga gtcgtaaaaa ggcctttgtt tacggacaag cttctggaat
     6181 cgttgaacca attgctggag tgattggagc gctactagta acgaaagtgg agctgctgct
     6241 tccttatgca cttgcttttg ccgcaggagc aatgatttat gtcgtggtgg aagaattgat
     6301 ccctgaagca cagcagacat tgtccagcaa acgtcatttt gcagtttttg gcgtcatgag
     6361 tggatttatc attatgatga ttttggatgt ggcattagga taaataaaaa aaatatatat
     6421 gatatatcaa atagggccgc gaacttatat cgcgacccta tttttttagt aagttatatc
     6481 ataatgaagt gaatggtatc atacattaat aatagttttt tctatgtgta tttcctttga
     6541 tccagcgaac aagccagatg ataagtgcga ttgggattag aactttgacc gcaaaccata
     6601 aaagcccgct taggacactg acaaaaagac tgatgacgaa gctagctgca attagcacta
     6661 aaagaaccat gaagatattt aagaacatat ttttttgacg catacaaaac cctcctcttg
     6721 ttcattcttt actatagaaa aagtataaca gggattgttt aaaaacacct ccaactgaag
     6781 actgattttt acttcatcta cttaaatgat caaacaattg ctttttctct ggtttatcat
     6841 ctaaaataga gcggaaaagg aggagaatat catgcctaaa aatcgtcttg aagcatttac
     6901 agatgctgta atcgcgatta tcatgactat tttagtttta gaacttcatg aacctaacgg
     6961 agacacgtgg gaggcgctcg ctgcattagg ttaccgattt tttatctata ttgtcagttt
     7021 tatcatttta gcgatttatt ggaacaatca tcatcattta tttcaagttg tacataagat
     7081 aaatggacgg gtcttatggg cgaacagttt ctttgttttt gcgctttcgc tttttccgtt
     7141 tgcaacttca tggatcagtg agtacatcaa tagcctggct ccagaaatga cttatggttt
     7201 tgttaccttg accgctaata ttgcgtatta tatcttggca aaagaacttg tcaaagcaaa
     7261 taaaggccac gagaaagcat tgaaggcgat gttgaataat tacaagaaat cgtatctatc
     7321 gattggtttg aatgtgttag gaattgtctt agggtattta gtagcgccag tagccgtgct
     7381 gatcgcaaac atcgtgattc tagctgcttg gatcatccca agtcgtacca tcgaatcaca
     7441 atatcggtaa aatgatccgt gtttaaaatt taagagaaaa atatagaaaa aataaataaa
     7501 cgatcaaata tccgagtgat actagtattc aaagagggat gcagatggat caaaaaagaa
     7561 ttcatgtagg actgattact agttttgtca cgatgcttat ttatttggat caaggtcatt
     7621 tgacttggac agtagttggt gtcgtaggat ttttgacatt attcacagca ataaaaaaat
     7681 aaacatcttt atgtaatctg atgttctatc tatttaagaa aagcatgttt acagcagtat
     7741 gattctgttg taaacgtgtt tttatttgtg gaaaatttaa tttttagaaa agtgtatcga
     7801 aaaatagata gttagttttt ccacagtgga taacttcgta agagataaaa ataaaaaatt
     7861 agtcaaagaa gggcgtatag atttcttttg ataggagata tacaacagaa atgaataaat
     7921 attaacgtgt tttcaaacag tataaaacgg tgtggttttt ggaataaaaa aataacatat
     7981 ctcattttac acttttgtta ttttatactt aaaaaataac gacacagaaa ataccgtgtc
     8041 tcagatttct ctactacttc taaaaactac tgtttttttc ctttgaaatg ccttcaaaaa
     8101 gtaggatcag gcagaatata ctggcagaat caaggagaag ggagcctaaa taaggagaaa
     8161 aaccatagaa aatataaagt aattacttat aaaacaagct ttttatagaa aaataatata
     8221 cctgagtagg gtataaatta agacggaatt cctttctaga ttgagatatt gactaggaag
     8281 aatgttaaga ttttaagcct ttaagctaaa aaaaaaccct ttttgttaaa taaggggaat
     8341 atagcctgtc agtttcaaac tgcaagtcgt cctgctgcaa taatatagta gattagagat
     8401 gaaaatagat ttttttaaac caatgactga ataaaaagac cgtcatagat acacattgga
     8461 atgtgtctat tacggtcttt ttttacgaac gattttattg aagacggaca gttcgggtca
     8521 aaaataaaaa agctacgatc agaaataaga ataaaatgta tcccaaaata atggctagac
     8581 ggtctaactt atttgtcgat agatgtttgt ttagaagttg ataggcccat aaacctatca
     8641 gtcctcctgt tgtattagtt atcaaatcag tgatgtccgc tacgccaata ccgaatagga
     8701 attgaatcaa ttctgccaag aagcttacaa ggaaaataat ccctaatttt ttagaaaaag
     8761 aaagtctctt gaaattgaca ttcaaaagca ccccaaaagg aaaaaagaca atcaagttat
     8821 aagtggtctc acgtaatacc gtcgtatttt caaaagaaaa agtagaaaaa gggacgagat
     8881 tgacattgct gtaagaataa gtgagaaatt gtggaagatt aaatgatagc ttgaataaaa
     8941 tcaaccataa tagaaagaat aaataaatcc ctaataaaaa ttttgataca taccgcatag
     9001 acatctcctc catttaaaaa gtataccatc gaaaaccgct gaaaaatcat aaaaaagtat
     9061 gaagtttaag gaccaacgta gttatcgtac gaaaattaga agcttttttt tgttgggaat
     9121 ccggtttctt taacaaagct aagatagcga gttgcttgga aaagttgcta tcttttttct
     9181 gtcaaaacga ctcggaatgt tcgttttttg ttctaatttc tccaagttgt ttactttttg
     9241 atactaagtt tatgaaaaat caagaaatag ttgttatact aggtaatgct gacaaacggg
     9301 attggcattt catcttggtt cagctttttt tccaattact aggaaggagg gatagattgt
     9361 tcaagactta ttttcgtttc aataaaatac aagataatcc ttttcgtatc atgaatctga
     9421 tgctacttat ctttattgta ttatggttag gttacataaa tcatgatttt ttgatttcaa
     9481 gtttttcatc attagggatc tttacttttt tctattatca aaacataccg atgaaatatt
     9541 tgctgaaacg tatgtttctg atcggttgcg gactgttggt tgctttcgtt ttggggatct
     9601 tatcgactta tgttttatgg cttgaaccat ttgccgtagc tttggttgct ttttccagca
     9661 gattcgtgtt gcgattattc catatttcta aaccaggtgg cttgtttttt gcgatgcttt
     9721 ctgccatggg aacgagcatg cagctgccaa tcgctcaatt accgatcgtc tcactttatt
     9781 tttttatggg tgtcgttttt gccctgattg cggcagtgat tacaaaatta ctggattcac
     9841 ggcctgagca gacaattgaa aaagcaactt taaaagaaag atttcacgaa gagcctttag
     9901 tgatcattga ttctgttttc tacagcgctg ccttatttct ttccgtttat gtcagtcacg
     9961 gcttgaatct gcataatcct tattggttga ccttgtcatg tgcatcgatt ttgctagcag
    10021 aaaacttgga tgcgatgaag catcgacaag tccaatatct gattggatcg atgggtgggt
    10081 tatgtgtgtc ggcattcttg tcatttgtgc cgtttacgca gttgcagacc atttttctga
    10141 tcacttttct atatggaatc gcacaatttc tagttgctag aaattatgca gttgctaata
    10201 tttttcttaa tccgatggcg ttgatgctat ctacacttat tcgtggagca tacttgattt
    10261 ctttgatcga atatcgtttt ttagggatcg tcataggaag tttcatcggt ttaggtgttg
    10321 cgtgggtaat gacggttggt ttgcaacatt atttaacggt tgttcgtcaa aaattagaat
    10381 agaaggacaa atatatgtgc caaaagaggt tatgacaaga tttttgtcac aacctctaat
    10441 tcaaggtgtt caaaagccag attctcagca ttaagtcaaa ttcacacaaa aatgtggaaa
    10501 ggaactttca aaaaaatttt atatttattc tatcaaaaaa ttttgtttat gatggtaact
    10561 gaataaactt tcctgagatg gtcaatgctt tccttgaaag tcttacagat attctttctt
    10621 catagaaagt ttaagtttta tagttagtgt acaataaaag tatgtttata ccatatggtg
    10681 tccggataat cagtcattta aacaatgagg ttcaaagata tgaaaagggg aaatttgatg
    10741 aagaaaataa gcaatgaaat ccaaattctg gcagaaactt taactcttcc caaagtcgtt
    10801 atagagcaaa tgattgtaca agcaaaaaac atccttgatg aggtgtttga gcaatatagt
    10861 catgaactaa tggatcctaa taaagcaaag gcgactgcaa agaaaataga caaagtctat
    10921 gaagaggaac cttttgcagc attagctatt tatctatatg cagcttctca aagttggaaa
    10981 aaaatttatc aaccattgaa gattccaaga actatctatt tggcaacaat gaatgctttt
    11041 actagattta ttcatgaaca tttccaagta acaggaagct atcgctttga ccgtggtttt
    11101 tggatttggc attacactag tggcttgatc tttcggattg gtgaattgga gtacgaaatg
    11161 acatattttc cgaaagggta cacggatcta agattagaag gaaagcagtg cctttctctt
    11221 catattcctt ccgatgcaga tttatctcag aataagataa gagatagtta cgaaagtgcc
    11281 attcgttttt ttgaacttta ttttcctgat taccattacc aagtgatgta cacagatact
    11341 tggttactat cacccaatct tactaaatgg ttgaaaaaag agtcaaaaat ctgtcttttt
    11401 gcagccgatt atcgattatt atcagttgat gaacaggacg atagtggagt cccttggatc
    11461 tttggacgag tagatgccca aatacatgat tatccagaaa gtacgagttt acagcgacaa
    11521 gcaaaagagc aattgcttgc aggcgagcac attggctctg gcttaggtat tcttacttca
    11581 taagtttagt acttcgaaat agtttaaaag agcgtgagac aaaagtaaag aacacttttg
    11641 tctcacgctc taaacacgta taaacggcgg aagcagaagc aactccttcg gaaataagct
    11701 gaaattcaca aaaatttgaa aagcaatttt cgtgaatttc ttcttatttc ttggagttaa
    11761 acgcttctgt cccagcctct tttttagtgt tctatcgaac acacagtacg ttcaataggt
    11821 aaactagcta taacaataga tattaaagtt aacggacaag agggcctttt ttaggtagct
    11881 aaaacgtaat aatgaaaatt tatttccaga gataggagtc aatcagctag tctgatcgac
    11941 tgttttaaca agttgacttt cattttaact tttgatacca tttaaaacac aaatcgtaat
    12001 tgtttcgatt tgtgtttttt agcatgacta caatcaaaga agaaagtggg tcgtccatat
    12061 ggaaaaaaca gatatctcaa gtgcataccg ccgcttgaaa agcccaaata tcaaaacacg
    12121 aaaacgtgcg ctgaagatca tcaaagatgt gaaacggaat agtgggaaaa ggtaagaaga
    12181 aggaaactta attaaaaaaa tagccgaaaa acgtttttcg gctattttca ataatcggtt
    12241 tttgtgtaag gtttccgaaa gaactgctgt tgattttcca tttttaacat atgataaatt
    12301 ggtagaatct ttcttttcaa attgatacca ttccctaatt ccagttatat agttaactac
    12361 agaaccacaa agcacgtacg tttataaaag tattatctgt agttattttt caattccctt
    12421 tcaacctctt attttgacca gtagtattga tcactttacc ttttaacacc tttgttcgtt
    12481 tttgaaacat ttttagtcaa gaatggaaac gtaactacat aatcaaaggt tttgcgaaat
    12541 atttcatgaa atatttcatg tagaagcgag caatacggtt gcaaataacc attatcgttt
    12601 aataagcagt tacgaaagct cccaatatct ctaacgttca gctcactcca tttcttttct
    12661 tcaaaaaaat cagtgattcg tatctctttc tatttgtcga aaaagttaac tttaaaaagt
    12721 aacgccgaaa aaatatgcaa aaaaataaaa aagcagttac tattgctaga ataacatcaa
    12781 ggaataataa gttttggttt tcagataata gtcgataagt tgtgtattgg aattttagat
    12841 acagtaataa agtatttttc atgaaatttt gtgagaatca ctattacaag tatctttaat
    12901 aaaattaatg gttaaggagg aacttaaagt agaatgtaaa tgaatagttg tagtcagtcg
    12961 attgtgatac tagactcaaa gttgcaggaa taagtttttc aatttgtgat tggaagataa
    13021 aaaatgaaaa agaagggctt ttttttatac tttgttgatt gtagtgttta ttttccctct
    13081 gtttagccaa gtaacatttt ctatgactca accagtttca agtgaggaac atgataacct
    13141 ttttcgtgct acagaagagt ttaagaaata tcaggaaaat attgttccgg agactccatt
    13201 agctagtgag ccaattactg atattgatgg aaaccaaata ggatggtata tacagtacga
    13261 agttatggtg gtaaataatg actcaatagt aaaaaataca gtaggcttag agctaacacc
    13321 gattgaaaag gtgagttcat tgttaacgta tatttatact gatgaaagtg acgagactga
    13381 gatcatttta acggattact caaaaattgc tactgataaa aagtatatat tgtggatgta
    13441 gacactagtg aaatacttta tgatatagaa attgatgaaa atttactaga tgtagcacaa
    13501 gaaatcgatc atcaaaagca ggaagctatt cgatatgctg gtagaaaagg gaaaagaaaa
    13561 tatttattac gtgaatgtag caaaagttag agaagatgaa aatgagtgga aagaattcaa
    13621 gagtcgctac tcaattaact cgactccgac atttacagtt tacagagaag gatcgataga
    13681 aaaaactgtt ttttggacta aagaaagtgg aatgtcttta gctgaagtag aagagttttt
    13741 ggattatgtt agtatgcaac agtaagggag ttcttattat gaaaaatttt gacacatatt
    13801 atgttattgt tttttcgata tctttgctgt taatattact aactttaatg cagtataaag
    13861 agtatccaga gtattttatt ttaacttttg tatatttagt aagtagctac acacttctat
    13921 ataaattcag aagttcttct agagtttcta aagtttgttt cttaattagc ttattgattc
    13981 tataatattt ttgatttata taggaaatta aaaatattat agaatcaaca ctcagagaac
    14041 gggttggttt ttaatagatt taataagtac tgataatgaa atttctcctg gttgggaaaa
    14101 cgaagttggt taccctgtag aagaattttt tcaagattac tttgcggagt atgccgatag
    14161 gataatgaga gattacgtaa cagataaaac tcaagaagtc atcaatcaat cccagtcatt
    14221 aaatgaatta tctgataagg cgaaagaaga agcagttgcc attatttctt cagggattag
    14281 tgactatatt gatatgagtg gtgaaatcaa ttatggcgat aaagacaaaa ttgtacgcat
    14341 gataaaagct tttatcaaaa cttttgatgt gaaggcagat cttaagttta atgatactta
    14401 cctagtagga aaattaatta atatccttgg gacagagaaa gatacggaaa cgtttatttc
    14461 ctctttgtct atgttgttta cagataagca tttttcaact cagcttggtg gagaggaact
    14521 agtggaaatc ttttaaccat tacgcccagc attaataaaa gtatatcaaa aaagtactcc
    14581 tgatgatttt taagattggt ttgagaaata atgtgaaaac actattttta atgttaatta
    14641 tagatagaga tgaacgcgtc atatggttaa aagaatgaaa aagtcaaaga tacactgcta
    14701 tatttcacta aggatatagc agtgtatctt tcatgtcgtt tcactggcag ttttttataa
    14761 aaggaggtgt gcatttcagt tgcttttctt tggtagttag ttgaatcgtt taagaattaa
    14821 cggatgtggc agacaggtgc tctgtccaaa aaccagtaaa atctttgatg gttccatctt
    14881 tatttagctg tgcctgttca aatactgttt tgtttttacc gaatggatca attgcaataa
    14941 ttgttccgat ccccgcacgt ttggcagcaa gtaatcctga gtaagcatct tcgataacaa
    15001 gacaatcagc cggagctaag ctcagtttgt ctgccgcttt aagaaaaata tccggttgcg
    15061 gtttcccagg gaaagagccg tcgtcataga caatcttgtc ccagtcaaac cagcgggcta
    15121 aatcgaaaat atcaaaataa aaagcaacat tctctttgac agtagccgtg gcaatcgtta
    15181 atggaatctg ttggtcagtc agctggtcaa gagtcgcttc aagccctttt gtcaactgaa
    15241 gctcgttttc attttgcaag caaagcatac gataatagct ttctttttct tctgacaata
    15301 cggcgatctc agaggcggtc aaatgctctg aaatgaaatg tttcaaaatc tccgtattcg
    15361 tccgaccatg aatatttttt aaaatatcct cgtctgataa accatctttt gtatgatcat
    15421 gtatcatatg cagccaagca gcttcatgca gatgagagtc caaaaacatt gttccgttga
    15481 aatcaaatat aatccctttc atagttacgc tcctatagtg gtattttcgg ttgaatcagc
    15541 aatttgcaga tcgacatatt gtgcatagtg ctcttgaacc tcccgcgaga tctggcgatc
    15601 cgtaatgagc agatcgaaat catgcaaatt ataaaacaca taaaaatcat ctcgattgaa
    15661 ttttttatta tcaacgagta gatatttctt acgggaatta tttagagcga tctgctgtgc
    15721 ttctccttct tcggtactgt aagtagagat cgcttcgttg tgaacgccat ttgaactgat
    15781 aaatgctttt gtaaacttta gtcttcttaa attgtcgttg gtgatcggtc cgacaaatgc
    15841 gccggtattt ttccggaaat caccgccaat cagtagaatt tctggtccat ctgcttgagc
    15901 aagaatatca aaaactggat aattatttgt aatgatccga attttcttgt tcagtaaatg
    15961 cgtcgccaat agttcgattg ttgtacctgg tcctaagaaa atcgtttctc cctcgtgaat
    16021 caaggaggct gctgtggcag caatttcttt tttttcttga atctgcagag tggctttttc
    16081 agtgtgagaa agttcttgat ctaaagtgta ggaaagactt tgagcccctc catggacacg
    16141 cagcagcttg cccgattttt ctaattcatc taaatctctg cgaacggtca tatcagaaac
    16201 atctaattga ttgatgattt cattaacggt aaggattcct tttttattga ccatttctac
    16261 gatagtaagc aatctttctt ttttcaacat tgtcttcacc tctaatttaa ggataatcta
    16321 tcatataaac ggacaacagt caatctaatt cgaacaaaag taaacattta gggtggtttt
    16381 tatgtttgtt acaatagatt ttattgctgt tttctggttt ttatgattat ttgtgtttgt
    16441 ttttgttgac aaatgttttg gatgcgttta caatgcaatc agttagaaag agcgaaaact
    16501 gattatagat ttgaggagag atgtacatgc ttaaattacc agaagatttt atttttggcg
    16561 gagccacagc agcctatcag gttgaaggag ccactaagga aggtggcaaa ggcgctgttg
    16621 cttgggatga ctttttagag gaacaagggc gattcagtcc cgatccggca agtgattttt
    16681 atcatcaata tgcaaaggac attgaattgt gtgaacgttt tggtgtaaat ggtctaagat
    16741 tatccattgc ttggagccgc atttttcctg atggagctgg gaaaccaaat ccagaaggaa
    16801 tcgcttttta tcatcgtgtg ttcgaagaat gtaagaaaag aaacgtaacg ccgtttgtga
    16861 cgttgcatca ttttgatacc cctaaacgtt tgtttgacca tggagatttt ttgaatcgag
    16921 aaacaataga agcatttgtt tcctatgcca ttttttgttt tcatgaattc aaagaagtca
    16981 aggtgtggag tacctttaat gaaatctatc cagttgcaac caatcaatat ttgttaggtg
    17041 ttttcccacc aggaatcaaa tatgatttta caaagatcgt cgcctgtctt cataatatga
    17101 tggttgctca tgcccgtgta gtgaactatt tcaaagaaaa cgaacttccg ggtgaaattg
    17161 gtgtagttca ctcattagag acgaaatatg cggcaacaga cgcgccggaa gataagcatg
    17221 ctgccttttt agacgatgca ttgtcgatcc gtttcttatt agatgctacc tatttaggct
    17281 attattcaac tgaaaccttg actgctcttg atgagatatg tgaagcaaat caggccagct
    17341 atcattttcc tgaagaagat ttcgttgaat tgaaaaaagc atccacgcgt aatgactact
    17401 tagggatcaa tcactaccaa tgccattttg tcaaagctta cgatggagaa aatgcaatcc
    17461 atcataacgg tacgggtgaa aaagggacct ctgtttataa agtgaaggga atcggagaac
    17521 gtatttataa agaaggaatt cctcgaactg attgggactg gctgatttat ccagaaggtc
    17581 tatatgactt gttgctgcga attaaaagcg attacccaca ttacaacaaa atctatatca
    17641 ctgagaacgg gatggggtat aaagatcagt ttgaagatgg cattattatg gatcagccga
    17701 gaatcgacta tttgagagtc tatttggaat ccttaagcaa ggcgataaca gccggggtaa
    17761 atgtgaaggg gtattttttg tggtcgctta tggatctttt ctcatggaca aatgggtata
    17821 acaaaaggta tggcttgttt tatgttgatt ttgaaaccca gaagcgttac ccaaaagaat
    17881 cagcttactg gtacaagttg gtcagtgaaa ccaaaacgat tatttaataa gtgataatgg
    17941 aggaagaaaa gatgaataaa gaggaattac aaatgcttgg ttttgagatc gttgcatatt
    18001 caggcgacgc tcgcagtaca ttattgaaat tattgaaaga agtaagacaa ggaaactttg
    18061 aacatgttga ttcggcgttg aaagaagccg acgaaaattt aacccttgca cataattcgc
    18121 aaacaaaaat tttagcggaa gaagcatctg ggaaagagat ggagatggga ttcattttta
    18181 tccatgggca ggatcattta atgaccactt tattgctgag agatctgatt caagacttta
    18241 ttgtactgta cagacagaat caaggatagg agaagaacgc tatggatgga atcattaaac
    18301 aaatcgaaaa agggaaacca ttttttgaaa aaatctcacg taatagttat ttaggagccg
    18361 ttcgtgacgg atttttaaca gcgatgccag ctattttatt ttcaagcatt ttcattttga
    18421 ttgctgcggt tcctgagatt tttggttacc aatggcctga atctgtctcc acatggctat
    18481 ggaaagtcta taattattcg atgggtgttg tagggttact cgtttcagca accactgctc
    18541 gctgcttggc tgattcgatg aatcgtcgct taccgaaaaa caaagtaatc aacaccacct
    18601 ctgtgatgct ggcctctgtg gtaagtttcc tgttgttaag cgtctctccg attgaaggtg
    18661 gattttcaac ggaatatatg gggacaaagg gactactggc ttcctttgtc gctgcatttt
    18721 taacagttaa tttatataag ttttgtgtgc tgaaagatat taccattaaa atgcctaaag
    18781 aagttcctgg aacgatttcg caaaccttcc gagatatttt tcctttctct ttttcagtat
    18841 ttgcggccgt tttaattgat ttaggcattc gacaaatctt ccaaatctca tttgcagaag
    18901 caatcattac ggtgctgcag ccgctattta cagcagctga cgggtactta ggaatcgcta
    18961 ttatctgggg agcgatggcg ctgttttggt ttgtcggtgt tcatggaccg tcgatcgtgg
    19021 agccggcaat tgcggcaatt atctatgcca atgtggaaac caatctgcaa ttgttcaatt
    19081 ccggtgaaca agcttctaaa gtactgacgg tgggtttagg gaattttgta ggaactatgg
    19141 gaggaactgg ggcaacattg gttgttcctt ttatcttcct actctttgct aagtctaagc
    19201 agttgaaggc agttgggaaa gcttccttta ttccagtaag tttcgctgtc aacgaaccat
    19261 tgctatttgc ggcacccatg attttgaacc cttatttttt tattccattt ttgttaacac
    19321 ctgttgtaaa cgtttgcctg ttcaagtttt ttgtcgatgt attgggcatg aacagcttta
    19381 tgtacgtttt gccttgggca actccagcac cgatcggttt ggttctagga acgggcatgg
    19441 gtatcttagc ttttgttcta gcagcggttc taatcgtcgt tgacttcctg atctatctac
    19501 cattttgcaa agcatacgat gctgtcttag tagagaaaga agcacaaaaa gcagaggtga
    19561 tcgcaaccga ggaaggtgct tctgccgatg tacgtgagga agtacctgtg gcagcgagtc
    19621 aagttatcag cgatgcaaat aaagaaatca atgtgttggt actttgtgct ggcgcaggga
    19681 caagtgggat gttagctaat gctttaaaaa aaggtgcatc tgaatcgaaa gcaccgatca
    19741 gtgcaatggc gggtgcttat ggttctcatt acgaaatgct gcaggatttt gatatggtgg
    19801 tcttagcacc gcaagtcaat tcttactatg atgatatcaa agaagacacc gatcgcttag
    19861 gaatcaagct ggttgcgaca aaaggagcag aatatatcgg attaacgaga gatcctgaaa
    19921 aagctgttca gtttattctg aaccaatttc aataaaggag gagccataat gaaaatggga
    19981 atttggttgc gtaaagctgt tttatttgca gctgtgttag gggctttggg ggctgtttca
    20041 aaaactgttg aagcatctgc cagcgaattt attcgcggag cagatatttc gatcctgtca
    20101 gatatggaaa aatctggtgc aaaatattat gaagacgata tttcaaaaga tgccttagag
    20161 attttaaaaa ataatggtgt caactatgtt cgactgcgtt tgtggcagga tccttataat
    20221 agtaatggag aaagttatgg agcagggaca aatgatctgg aaacgacgat tgaccttgca
    20281 aaacgagcaa aaaatctggg acttaaggtg ctgctggatt ttcactacag tgatttttgg
    20341 gttgatcctg ggaaacagaa tcttcctaaa gcatggcaag gtctgacctt tgaagaaatg
    20401 aatacggcat tgtacgacta tacaaagaac gttctgtcgg aaatgaagca gctggacgtt
    20461 tatcctgata tggttcagat cggcaatgaa ctgaatagcg gaatgctctg gccttatggc
    20521 aagtcttggg gagaaggcgg gggagaattt gatcgattgg ctgctttttt gaagtctggt
    20581 atccaagctg ttcgagacac tcaacctaaa acaactccag taatgctcca cttagctgat
    20641 ggtggcgata caggagcatt tacttggtgg tttgatgaaa tcacgagtcg aggtgtgtca
    20701 tttgatttaa ttggagtgtc gtattatccg tattggcacg gttcaatgaa tgaacttcaa
    20761 accaatatga atgcgatcag ccaacggtat ggtaaagaag tgatcgtagt tgaaacagct
    20821 tatgggcata caacagcgaa tgccgatact atgccaaatg cttttggtga agccgaagca
    20881 gctgcggggg gatatgaacc aacaccgaca ggacaagcag agtatttgct ggatcttgcc
    20941 gatcggattc aggcagtacc gaataatcgc ggggcgggct tcttctattg ggaacctctt
    21001 tggtacaacg gaaatgtgag ttgggcaaca caagcaggta tgaattatct cagtgttcaa
    21061 tccactatgg gaaacgaatg ggacaaccaa gcgatgtttg attttgctgg aaacgccttg
    21121 ccaagcttgc gtgcgtttaa acaagcaggg gcgcaaataa atctagttaa aaatgcaagt
    21181 ttcgaaagcg atggaccaac gaccagtcct tccaattggc aaacctggtt tcaacaagga
    21241 accgctaagg gtacgatcaa aacggaagcg ggcacttttt ttggggacta caaactaact
    21301 ttttggcagg atcaagcata cgaggcatca gcttatcaaa atgttagtgg cataagcaaa
    21361 ggaacttaca cattgagtgc ctatgtaatg tctgggggag agtttgatac taatcagtta
    21421 tatatcaaaa attatggtgg agcggaacta aatactgcgg ttgttaaaac aagtgaatgg
    21481 acaaaaatta caatcaaaga cattccaatt acaacaggtg tttgtgaaat tggggtttat
    21541 agcaaggctt caggaaatgc ttggacgaac gttgattttg tttcattggt gaaacaatag
    21601 actgcggatc gtttcgattc aagatcggag gttcccttca gccacatcgt tagcgtagaa
    21661 ggcaggaatc gaacctgcac ctcgcctttg ccaaaaataa ccagaaacga tttccagtca
    21721 tttttaccaa aacgagtaaa gcaccagact tcatctacac tttgtattat gctaaagaga
    21781 gttcaacgat ttcgtaagaa gcaatgaaaa aattgcaaaa agttgtgcag ataacataaa
    21841 gtttgtttaa gaaagggtaa ccttagaatt ccgtcgtgaa tatgatttga gcacttagat
    21901 ggatagaaaa aagttctcgg aaaacagttc gtttttcgag aacttctttt tatgataaga
    21961 atgaaacaaa ttaacttata ttatagtctc ttttggtagg gaaccatctt atttttaatg
    22021 aaaatcaagc attttagcta ttgaagaatg ttgatttata gggattcccc ctccatatta
    22081 tgttggctct ttattcccac tccactgttg ctggtggttt agaagtgatg tcatacacga
    22141 tacggttgac gtgggctact tcgtttacga tacgtacaga gattttttgc aagacttccc
    22201 atgggatacg ggcaaagtca gcggtcattc cgtcgattga agttacagca cggataccga
    22261 ctgtgtagtc gtaagtacgt ccgtcaccca taacaccgac agagcggatc cctggaagaa
    22321 cagtgaaata ttgccagata tcacggtcaa gtccagcagc tgcgatttct tcacgcaaga
    22381 tagcatcaga ttcgcgtacg atttctagct tgtcttcagt gatttcgcca agaacacgaa
    22441 taccaagacc aggaccaggg aatggctgac gccaaacgat tgaatcaggc atgcctaact
    22501 gagtccctaa ttcacggact tcgtctttga ataatgtgtt taatggttcg atcaattcaa
    22561 attgcatatc ttctggcagt ccacctacat tatggtgaga tttgatcgtc tgtgctgttt
    22621 ctgtaccaga ttcgataacg tcagtataca acgttccttg tgctaggaaa gagacgcctt
    22681 cttcaccagc aagttttgtt gcttcgtcat caaaaacata tacgaattca ttcccaatga
    22741 ttttacgttt ttgttctggg tcagatacac ctttcaactt gtctaagaag cgatctcttg
    22801 cattgacttt gatgatgttc aagccgaatt ttccgcctag actttccatt acttgttccg
    22861 cttcgccttt gcgtagcaga ccgtggtcaa caaagataga tgtcaattgg tcaccgatcg
    22921 ctttttgtaa aagaacccca acgacactag aatcaacgcc acctgaaaga ccaagcaaga
    22981 cttttttgtc accaacttgt tcacggattt tttctacttg catatcgata aagttatcca
    23041 ttgtccagtt accttcacag tgacaaacat caaaggcaaa gtggcgcagc aattcgattc
    23101 cgtattcgga atgacgtact tctgcatgga attggatacc ataaaaatta cgtgttgtgt
    23161 cttggataga agcaatcgga caatctttgc ttgttccgac tgtttcaaag ccttcaggaa
    23221 ctttagttac caagtcacca tggctcatcc atactgtttg ttgttttggt gtttctttaa
    23281 acaagacagc ttgatcgctt gttacttcta acaaggcttt cccatattcg cggtttttag
    23341 caggctctac ggaaccgcca agtttgtacg tgatcaattg cataccatag caaatcccta
    23401 atacaggaat acctaaattg aagatctcag gatcgatccc aaatgcattc tcatcatata
    23461 cactgtttgg tccgccagaa agaatgattc cctttggatt catcgctttt acttcttctg
    23521 cagtaatgcg gtggctcaat aattcggaaa agactccaag atcacgaata cgtcttgtga
    23581 tcaattggtt atactgacta ccgtagtcta atacgataat cttttcaacg ttcgtcatat
    23641 cggcaacgtt tgtcaaattt attaccccta tccctttaaa ttttatctca aaatagtcaa
    23701 actattttaa aatgctaata ttttcgcatg aaaatcgaat cgatgatatg attttcagtt
    23761 ttatggagaa ttatatcggc tcttcctcgt gtaggcaaga tatattcctg taaatttttc
    23821 aaattcacat ttttccatac atcttttgcc attttaaagg cttcttcacg atctccgata
    23881 gcaaaacgat aataataatt ctctggattt tggaaagccg tatccagtaa cgcaccaaaa
    23941 cgatccaaat accatttttc gatcagcacg ggatcggcat cgacatagac agaaaaatca
    24001 aaaaagtcgc tgacgtagat ttgctgattc gcaggtaatt gaagcgtatt gatcccctca
    24061 acgatcaaga tatcaggctg ctggatcaat tcgtacttgt ctggaatgat atcatacaca
    24121 tcatgtgagt aaacaggtac ttttatctct tcctgaccag attttacacg gttcaagaaa
    24181 tcgatcagca tctccatatc ataactttca ggaaatcctt tacggtccat gattccacgc
    24241 tcttttaata tacgatttgg ataaagaaat ccgtcagtcg tgatcagctg aacgtttctt
    24301 cgtttgaagg tacgagacaa aatcgtctgc agcagtctgg ctgttgtact ttttccaacg
    24361 gctacacttc cggcgatccc gataataaaa ggcggtactt ctacgtattt atgaagaaat
    24421 aaacctttac tcaagaacaa agattcaaat tctttcatat aaagataaat cagatgagca
    24481 agaggtacat agatatctcg aacatcctgc atggaaatgc ggtcattcaa acttttgata
    24541 ttatctagtt catcttgtgt caaaggtgct tgcccattac gataaaattc tcgccattct
    24601 tctcttgcca cacggtagta gttcattgga tcattcatat tagcctcctg cgttctccca
    24661 tcaatggaac tattttaaca caaaataaac gcaaacccca ccacttaaga gagattgccg
    24721 atctttttgt ataatcttta taatagaaag aaacggagtc ttattcttga cttgcgcacg
    24781 gatacataaa aggatagact gttgtcatga aagaaatgag aaggatggaa gacatgacaa
    24841 atcattacta ttctgaacgc ccagatacgg cgcacgattt tgaacaatgg gcttttgagt
    24901 taaaaggcag aacctttcaa tttgtaacag attctggtgt attttcacgt gaaacagtgg
    24961 attatggttc acgtgtcctg attgatgctt tcgattggga agagttacct gatgaaggaa
    25021 agatcttaga tgtgggatgc gggtatggac cgattgggtt agctttggca tttgcgacac
    25081 agcggtttgt tgaaatggtc gacattaatg aacgagcggt aagtctagcg caaggaaacg
    25141 caaagcgtaa ccaaatcgaa catgttgata tccatcaatc gaatatctat gaagcagttc
    25201 atgaagaaac ctatgcagct atcgtaagca atccgccgat ccgtgctgga aaaaaagttg
    25261 tacatgaaat tttgacaggc gcatatcctc ggttgaagaa gggcggtaca ctgacaattg
    25321 tgatccagaa gaaacaagga gcgccgagtg cgcaaaagaa aatggaagaa acatttggta
    25381 atgcagaaat cgtcacaaaa gataaaggat attatatcat caaaagtgtg aaagaataac
    25441 tagctgaaaa atagtggagc gacgaaagag tggaactggg cgtgcatgta cgggtacgta
    25501 tcagttcttt ttttgttgag aagtttttaa aaacaaagaa ctattttttc ttcaaaaaga
    25561 aatagtagga acagagtcgt tgttttttac gataaaataa ataagataca gaacttgtat
    25621 agaaggctgc caagtcggta gataaaggag gtttttatca aaaaacatac tttccttttt
    25681 tctctattct tttcttgggg gttttggtac actgataggg aatttagata gaagggagcc
    25741 aataggatga agctgaccat cagagatatc gcagaaatgg caggcgtatc agtaacaact
    25801 gtctcacaga ttttgaataa caaaggaagc agatttagtg ataagacaag aaaaaaagtg
    25861 ttgtcgatcg tgaatgaaca tcattataag cccgattatt tcgcttcaaa tgtgatcaat
    25921 cgacattcaa agaccatcgg aatgatcgtc cctgatgtca ctgatttctt cttctccaaa
    25981 ctgatcgaag gtgtagagag ctatttgaat cctttgggct atgtgatcat gttatgcaat
    26041 tctcgtcata gccaagaaaa tgagatcaag tatttacaag agctttccca ccgctcagtg
    26101 gacggaatct tgctggccac accaaatatt ttacctgaga aatatgcatt agacagcggt
    26161 ttttatcaaa aaatgccaat cattttaatc gatcgcggat tgaatcgtcg ggataacgga
    26221 cggcttatcg taaaggaata tgagggcgcc tatcaagctg tttcgctgtt tattgaaaat
    26281 ggccatacga agatcggcat gctgaaggaa accactggat actatcaatt agaagaacgt
    26341 ttcaacggat atcgtcatgc gctgaaagat catggcctgc cttttaatgg gaaatttgtt
    26401 gaacatggag agttgactgt ccaaggtgga tatactgcat caaaaaaatt actcaaacat
    26461 aaagatatca cggctatttt ttgcgggaat gatgccatgg cgatcggatg ctatcaggcg
    26521 atcgatgaat tgggcaaaaa aatcccagaa gatatctcag tcataggatt cgatggatta
    26581 aagctgtcag aatacatgat tccgcaattg acgacagtgc agcagccaag ttttgatatt
    26641 ggattttatg ctgcacgttt cctgatcgat acgatcgaat ttcctcaaag aaaagttccg
    26701 aacaaagtgt tcgaaacaaa attaattatt cgtgagagcg taaaagtatt gacaaagggc
    26761 taactcggcg gtatattgct tatgtaagca tttacaaagg ctagttagtg ctttttttat
    26821 ttttagtaaa ccagtttact aaagtggttt acctttccta aaaataatgt ataataccga
    26881 atgaagacaa ggaggatcag gcaatgcgaa tggtggatct gattgaaaaa aagagggatg
    26941 gaaacgagct gtcgaaagag gaaatcgagt acatcgtcac gaactatacg aatggaaaga
    27001 ttccagatta tcaagtcagt gcattattga tggcaatttt ttatcaagac atgacaaatg
    27061 aagaaatcac gaacttaaca ttggcgattg ctaattctgg tgatgtcatc gatttgagtt
    27121 ctcttgaagg aataaaggta gataagcatt cgacaggtgg cgttggtgac acgaccacat
    27181 tgattttagc ccccctagta gctagtgtcg gagtgacagt ggctaaaatg tctggacgcg
    27241 gtctaggtta cacaggtggt acactagaca agctagaagc aattcccgga tttcagatcg
    27301 agctttcgga tgaagaattt gtacgcattg ttaatgaaag taaagtagcg gtaattggtc
    27361 aatcaggaaa cttggcaccg gcggacaaaa aattgtatgc cttgcgtgac gtcacagcga
    27421 ccgttgattc tcttccgctg attgccagtt cgattatgag taaaaaaatc gcggcaggag
    27481 cagatgcaat cgttttggat gtgaccactg gagacggtgc tttcatgaag aacatcgaag
    27541 atgcaagacg tctggcaaag accatgacga gcattgggaa actggctaac cgagaaacag
    27601 tggcggttat ctcagatatg tcagaacctc ttggcgaagc tatcggaaat agtctagaag
    27661 ttgtcgaggc aatcgaaaca ttacaaggaa atggtccaga agatctagta gaaatgtgct
    27721 acgccttagg aagccaaatg gttgttcttg ctggcaaagc taagacaacc gatgaagcaa
    27781 gaacgttgct tcaagaagct ctggaatcag gtaaagcgtt agcaaaattc aaagaaatga
    27841 tccaaaatca agggggagac ccagcgatcg tggaacatcc agaacgaatt ttgactgcac
    27901 gctacacaat ggagcttcct gctaaacaaa gcggagttgt gtcaaaaatc gtggcaaatg
    27961 aattaggaat tgctgcaatg atgctaggtg ctgggcgtaa aaccaaagaa gaagatattg
    28021 atcacgctgt tggattgaaa ctgcataaaa aaattggtga cactgtgaca aaaggtgagt
    28081 cactattgac gatctatagt aacgacgaag aaatcacttc tgtcattgaa ttattatata
    28141 aaaatattga aattggtgaa tcggcaatga agccaacgtt gattcatgac atcatcacag
    28201 aataaaggaa aaaagcggac tttaccgttt taaagaaaag gggaaaagaa atggaactaa
    28261 accgaatgat cgaccatact attttgaaag cagacgcatc taaagaagct gtgatgcaaa
    28321 ttatcgaaga agcaaaaaaa taccattttt attctgtctg catcaatcca gcatgggttg
    28381 cgctagcgaa agaacaatta caaggtgagc cagtagccgt atgtacagta atcgggtttc
    28441 ctctaggagc aaacacaccc gagacaaaag catttgaaac aacagatgcc atcaataacg
    28501 gtgcagatga agtcgatatg gtcatcaata tcggtgcttt gaaatcaaag gatgatcaac
    28561 aagtccaaaa agatatcgaa gcagttgttg aagcagcaaa agatcgtgcg cttgtcaaag
    28621 ttattattga aacatcgtta ttagatagag aagaaatcat ccgagcttgc gaaatagcaa
    28681 aagctgcagg cgctgatttt gtcaaaacat caactggttt ctcaacaggc ggagcaaagg
    28741 tagaggatgt ccgtttgatg cgtgaaactg taggaccaga aatgggtgtc aaagcttccg
    28801 gcggtatcca taacgaagaa gaagcaatgg caatgatcga agctggtgct acaagaatcg
    28861 gaacaagcgc aggagtagca atcgtatctg gttcaactgg tgaaggctat taattttttc
    28921 aaaggagaag ctcatggcag aactcaaaca agaatggatc aacacagcta ttgaagcgtt
    28981 agataaagcc tatgttcctt attcccattt tccggtaggc gcttgtctcg taacggaatc
    29041 aggcaagatt tatcaaggca tcaacattga gaatgcatca tttggattaa cgaattgtgc
    29101 cgagcgcaca gcttttttca aagcagtatc tgaaggagaa aaaacattta cgcatctagt
    29161 cgtagcgggg cacacccccg atcctatctc tccttgtggt gcatgtcgac aagtaatggc
    29221 agaattctgt tcccctgata tgccggttac gctagtagga gacaatggtg tgacgaaggc
    29281 aacgaccgtt cgtgcactgc tgccttatgc atttactgaa aaagatctat aactcatgtt
    29341 cattcagtca gctgactgtt gaaaaataaa acaattattt taggaggctt tacagaaatg
    29401 aaaaaagcaa aattatttgg tttaggtgct gtcgcactag cagcagggtt atttttaggt
    29461 gcatgcggca acaacggctc tactgattca tccggtggca aaagctcatc agacacaaca
    29521 actgcagcat tgatcacaga cacaggtggt gtagacgacc gttcattcaa ccagtcagct
    29581 tgggaaggac tagaaaaatg ggggaaagat caaggacttt cacgaggaaa tgatggcttc
    29641 caatatttcc aatcttcaaa tgaatcagat tacatcccaa atattgacca agcattgaat
    29701 gctggattca aaacgatttt tggtattggt tataaactaa aaccagcgat ccaagaacaa
    29761 gcaacaaaca atacaggtac gaactttgtt attatcgatg atgtcatcga tggattagat
    29821 aacgttgtat ctgcaacttt caaagacaac gaagcttctt atcttgcagg tgttgcagca
    29881 gcttatacga ctgaaacaaa cgtagtcggc tttatcggcg gtgtaaaagg tgaagtaatc
    29941 gatcgttttg atgctggatt caaagccggt gttgatgcag gtgcgaaaga attaggaaaa
    30001 gaaatcaaag tattgaatca atatgctggt gacttctctg ctccagataa aggacgttca
    30061 attgctcaag gtatgtatgc acaaaacgca gatatcatct tccatgcttc aggcggtaca
    30121 ggtaacggtg tattccaaga agcaaaatca ttgaacgaat caggcgacaa aaaagtttgg
    30181 gttatcggtg ttgaccgcga ccaatcagac gaaggcgaat acacattaaa cggcgaaaag
    30241 aaaaacttca cattgacatc tacactgaaa gcagttggaa cagtagtaga agatttggca
    30301 caaaaatcag cggacggtaa attccctggc ggcgaacaca ctgtttatgg attgaaagaa
    30361 gacggtgttg gtctaacaga aggacaactt tctgacgaag cgaaaaaagc agttgatgaa
    30421 gcaaaagaaa aaatcatttc aggtgacgta aaagttccag aaactcctga agaaaactaa
    30481 aaccatttct atagccttgt tagacacatg tttgacaagg ctatggtttg attagaacaa
    30541 gaattgttca tttatccaag ctgccttgtg acagtttgga taagggaaca actccctgaa
    30601 gtaatgtttg tttcaaaaga agaacgctca ctaagcgtga atcttagtca atcgttgccc
    30661 tagatagaaa tcgttaggat gtgaaaaaaa ggtggttcaa gaaaatattg tcatagaaat
    30721 gcagaatatt accaaagaat ttggaacatt caaggcaaat gacaacatca atttacaagt
    30781 aaaggcagga gaaattcatg cgttgcttgg agaaaacggt gctggcaaat ctacattgat
    30841 gaacgtgctt tccggattat tagagccgac atcagggaaa attttgatgc gtgggaaaga
    30901 agtaaagatc acaagtccga ccaaagccaa ccaattaggg attgggatgg tccatcagca
    30961 ctttatgctt gttgatgcct ttactgtaac agaaaacatc gtgttgggaa gcgagcctag
    31021 tcgcgcaggg atgcttgacc ataaaaaagc acgaaaagag atccaaaaag tttctgaaca
    31081 gtatggattg tcagtcaacc cagatgctta cgttcgtgat atttcagttg gaatggaaca
    31141 acgggtagaa attttaaaaa cactttaccg aggagcagat gtactgattt ttgatgagcc
    31201 gacagctgta ttgacccctc aagaaattga tgaattaatc gtgatcatga aggaattagt
    31261 caaagaaggc aagtcgatca ttttgattac gcataagtta gatgaaatca aagcagtagc
    31321 tgaccgctgt acagttatcc gccgtggaaa aggaatcggt acagtcaacg ttaaagacgt
    31381 aacctcacaa caattagccg atatgatggt tggaagaacg gtttcattca aaacgatgaa
    31441 aaaagaagcg aagcctcaag aagtcgtttt gtctattgaa aatctagtgg tgaaagaaaa
    31501 tcgtggatta gaagccgtga aaaacttgaa cttagaggtt cgtgctggcg aagtacttgg
    31561 tatcgctgga atcgatggaa acgggcagtc ggagttgatc caagctttga ctggtttgcg
    31621 aaaggcagaa agcggacata tcaagctaaa aggggaagac atcactaata aaaaaccccg
    31681 aaaaatcact gaacatggtg taggacacgt gccagaagac cgtcataaat acgggttagt
    31741 cctagatatg acattatctg aaaatatcgc actacaaacc tatcatcaaa aaccttacag
    31801 taaaaacggc atgctgaatt attcagtaat gaatgaacat gccagagaat tgatcgaaga
    31861 atatgatgtt cgaacaacga atgaacttgt tcccgcaaaa gctttatcag gcggaaatca
    31921 gcaaaaagca attatcgctc gtgaagtcga ccgagatcct gatctgttga ttgttgcaaa
    31981 tccaactcgt ggactggatg taggtgcgat cgaatttatt cataaacgtc tgatcgaaca
    32041 aagggacaaa tacaaagcag tgttactgat cagtttcgaa ttagaagaaa ttttaaatgt
    32101 ttcggatcgt attgctgtta tccatgaagg agaaattgtc ggtatcgttg atccgaaaga
    32161 aacatctgaa aatgaattag gtctattgat ggcgggctat accttagaag aagcacgaaa
    32221 agagttagaa aagggggctg gcgcacatga atgatcgcag cgaaaaattc cgtaatttat
    32281 tagtgcctgt actttcagtt gttttaggat tgatcttagg cgcgatattg atggctgctt
    32341 ttggttttca gcccatccaa ggttattctt ctatgctaga tgcagccctt ggttcgcaaa
    32401 gagggatagg tgaaacgtta aggcaagcaa cgccgttgat ttttacagca ttaggttttt
    32461 ctgtagctaa ctcagctggg tttttcaata ttgggctttc tggacaagca ctttgcgggt
    32521 ggatcgtcag tgtctgggtg gcacttgcgt ttccagatct gccaaaagtt gttttgcttc
    32581 cgttatgcgt gatcttaggt gccttagctg gtgcgatggc agcggctgtt ccaggtttac
    32641 ttcgagcatt ttttggaaca agtgaagtga tcgtaacaat catgatgaac tatatcttat
    32701 tatacgtaag cacatttgct ttacatgaag tgatgcctga aagctatcgc tcaagtttgg
    32761 actcttccaa tatgatcagt caaaatgcct cactgcggtt accatggtta acacaagctt
    32821 ttggcggctc tcgcgtaaac tcaggattat ttttagcaat catcgcgctt attttcgttt
    32881 ggctgctgat gaagaaaacg actttaggat ttgaaatccg ttctgttgga ttgaatcctt
    32941 ttgcttctga gtatgcagga atgagtagta aacgtacgat cgttttgtcg atggtcattt
    33001 ctggcgcttt ggcagggctt ggcggtgtgg ttgaaggatt aggaacgtat caaaacttct
    33061 ttgttcaaac gacttcgcta tctattggat ttgacggaat ggctgtttcc ttgcttggtt
    33121 ctggatcagc aatcggtatt cttttatcag cgatcttgtt cagtattttg aagatcggtg
    33181 gacttggcat gcagacagga gcaggtgttc cgtttgagat cgtcaatgta tcgattgctt
    33241 tgattatctt ctttgtcggg atcaacttcc tgattcgttt cgtcatggct aaagtcttcc
    33301 aagggaaaaa acaagaagag atcgttgcga caatagaatc gaaaccaacg aatcaaaacc
    33361 atgaaggggg cgaactataa tgtcgactat cgaattaatt gccttgatcc ttacttctac
    33421 actggtttat tcaacaccgc taattctaac gtcactaggc ggaacttttt ctgaacgaag
    33481 cgggatcgta aacgtagggc tagagggaat catggtcatg ggtgctttta gttccatcgt
    33541 tttcaacttg acgatgagtc catcacttgg ttctatgaca ccatggatcg ctattttagt
    33601 gggtggcgtc gtaggtatcc tattttctct gattcacgca gtagcaacag tcagtttgcg
    33661 tgctgaccat attatcagcg ggacagtaat taatctgatg gcacctgctt taggtgtttt
    33721 cttgatcaaa gcatggtatg gtaaaggtca aactgataac atcacgcaga atctggggta
    33781 tttttctttc ccaggattag cagatattcc ggtcattgga ccaattttct ttaaaaatac
    33841 attcttacct gcttattgtg ctattttgat tgctgtccta gcttgggtga tcatcttcaa
    33901 gacgaaattc ggcttgcgcc tccgttcagt tggtgaaaat cctcaagctg ccgacacatt
    33961 aggtatcaat gtatatgcta tgcgttattc aggcgtactg atttctggct tgttaggcgg
    34021 tatgggcggt gctgtttttg ctcagtcgat ttccggtaac ttttcagctg gtacgatcgt
    34081 tggacaaggg ttcatctcca tggctgctat gatctttggt aagtggaatc ctttaggggc
    34141 aatgggtgcc tcattgttct ttggttttgc tcaaagcttg agtatcattg gcgcacaatt
    34201 accagttatt tcttcgattc cgccagtatt gctgcaaatt gctccatatt tgctgacaat
    34261 cattgtgctg gttgttttct tagggaaagc ttctggtcca aaagcaaacg ggaagaacta
    34321 tatcaaatca aaataatctt ttagcgaata aaaagggtgg gttacgggaa gtgtttttcg
    34381 tctcgccctt tttgttttaa aggcaataaa aataaaaaga aagaaggaat aatcatgttt
    34441 aaacgcgtac atctgatcgt catggattca gtaggaattg gagaagcacc agatgccgat
    34501 aagttcggtg atgttggttc tgatacatta ggacacattg cgaaagaagc aggattgaac
    34561 gttccacatt tagagcagct tggtttagga acgatccgtc ctcttgaagg tgtggaatca
    34621 gtgaaagatc atcaaggcta tgcgacgaaa ttagaagaag tttctgtagg gaaagatacg
    34681 atgacaggcc actgggaaat catgggattg aatatcaaaa ctccatttcg tgtgtttcct
    34741 aatggattcc ctgatgatct gatcaaacaa atcgaagaat tttctggccg taaagtcgta
    34801 tgtaacaaac cttatagcgg aacagctgtt attgacgatt acggtgaaca ccaaatgaaa
    34861 acaggcgatt taattgtata tacttctgcc gatcctgtcc ttcagatcgc ggcacatgaa
    34921 gaaatcattc ctttagaaga attatatcgg atttgccaat tcgttcgtga tataacaaaa
    34981 gatgatccgt atatgattgg ccgaatcatt gcacgtccgt acgtgggtga accaggagac
    35041 ttcacacgaa caagcaatcg ccatgattat gcgttgaatc cattcggaca cacagtcctt
    35101 gattctttga aagaagcagg aaaggacgtg attgctgttg gaaagatcaa cgatattttc
    35161 aacggacaag gaatcactga atctgtccgc acgaaaagca atatggatgg cgttgaccag
    35221 ctgctgaaag ttatgaaaaa cgatttttca ggaatcagct ttaccaattt agtagatttt
    35281 gatgcattat acggtcatcg tcgggatgta gtcggctatg cgcatgcgat tgaagaattt
    35341 gacttacgaa ttccagaatt gcttgaagcg atggaagaag acgacttgct aatgattaca
    35401 gccgatcacg gaaacgatcc gacgtttact ggtaccgatc atacgcgaga atatgtaccg
    35461 ttattggttt acagtaaaaa aatgaaagaa caaggggcat tgcctcaagg atattattca
    35521 gatatttcag caacgattgc tgagaacttt agtgtttctt cgactgaaaa tggcgaaagc
    35581 ttcttgaaat tattaaaata atctttttaa ataggagaaa gcaaatgacc aagttaagcg
    35641 agatgttaca agaaacgacc cagtttatcc ttgataaagg agtaaaagaa attgattttg
    35701 gtttgattct aggttcagga ttaggtgaat tagcagatga aatcgaagat gctgtaatga
    35761 tttcttatga tgagatcccg ttctttcctg tttcgacagt agttgggcat gcaggaaagc
    35821 tagtttatgg gtctctggca ggcaagaaag tgttagccat gcaagggaga ttccactact
    35881 atgaaggtca ttccatgcaa acagtgacct atccagtacg tgtgatggcc ggactagggg
    35941 cccattcagt cattgtgact aatgcatgtg gtggtgtcaa cgaatcattt gtaccaggag
    36001 atttgatgct gattaccgat catatcaatt ttactggtga aaatcctttg atcggtccga
    36061 atgaagatgc aatgggccct agatttccag atatgagtca agcttatacg cctgactatc
    36121 aagcaacagc aaaagcagca gcagaaaaac taggtttgga tcttaaagaa ggcgtatata
    36181 tgggctattc tggaccaact tatgaaacgc ctgcggagat ccgaatgtct cggacaatag
    36241 gagccgatgc agtagggatg tcgactgttc cagaagtcat cgtagcagct cacagcggat
    36301 taaaagtgtt aggaatctct tgtattacca acttagcagc aggtatgcaa gcgaatctga
    36361 gccatgaaga agttgtagaa acaactcaga gagtcaaaca atcttttaaa gcattggtta
    36421 aagaaacatt gacattattg taataggagg aacaataaaa tgagtgtgca tattgaagcg
    36481 aaagaaggcg agatcgccga taagatttta cttccgggag atcctttgcg agctaaatat
    36541 attgcggaga cttttttgga agatccagtt tgttacaatc aggtacgcgg tatgttaggc
    36601 tttaccggca aatataaagg agaacgtatt tctgttcaag gaacaggaat gggaatgcca
    36661 tcagccacca tctatgccca tgaattgatc cagtcgtatg gtgtaaagaa attgattcga
    36721 gtaggtacat gcggtgcatt gtcaaaagac gtccatgttc gtgatttagt actagcacaa
    36781 ggtgcagcga ccagttcttc gatgatcgaa aaaaatttcc aagcctttca ttttcctcca
    36841 atcagtgatt tcaatctatt actgaaagca tatgagatag ctaaagaaaa gggctatacg
    36901 gttcatgtag gaaatgttct ttcggaagat tctttctaca aagatgattt gacagagacg
    36961 ttccaattag ctgaacttgg cgttttagga gtggaaatgg aagcagcggc tctttattac
    37021 ttaggcgcga aataccatgt gcagacatta agtttgatga ccgttagcga ccatttgatc
    37081 accggtgaag aaacaacagc tgcagaacgt caatctacgt tcaatgaaat gatcgaagta
    37141 ggattggaaa cagcgatagc agaataagaa ggaaatgaaa aagctgccct gcattaagta
    37201 ataagaacat ccaagcaaaa atagctcctc atgtttttga cttggctgga cttattattg
    37261 caaatgtaag cttttgaaca ccgtttacca agaggttgtg aatctgccgt ttaactctga
    37321 gtcacaagga acaatttcaa aaaacagctt ttcatgtttg atgaatattg tgacttgtga
    37381 ccgagaagtt ggcaggagaa aaccgtttat acgaaaaaag ggactgtgac aaatcgtgtc
    37441 acagtccctt ttttatagtg ttttttatag gtagtatttt ttagcaactg ttaagtcatc
    37501 atttaattca taaacaagtg gttgacctgt tggaatttca agatccatga tgtcttcgtc
    37561 agagatacct tcgatatgtt tagctagggc gcgtaatgag ttaccatgtg cagctactaa
    37621 aacagttttg ttgtctagta atgctggagc aatttcatct tgccagaatg gcaaagcgcg
    37681 ttctaatgtc actttcaagt tttctccacc aggaatatcg cgtttgtcta acattgcgta
    37741 acgacggtca tttgctgcag aaccttcgtc agtttcttcc attaatggag gaagagtatc
    37801 gtaagaacga cgccagatgt gcacttgttc gtcgccgtat ttttcagctg tttctttttt
    37861 gttcaaacct tgtaatttac catagtgacg ttcgtttaag cgccatgatt tgatttgtgg
    37921 tacccaaagt tgatctgaat attctaagat caagttacat gttttgattg cacgagttaa
    37981 aacagaagtg taagcaacat caaattcgat tccagcttct ttgattttgc gtccgccttc
    38041 ttttgcttct tcgattcctt ctggtgctag atttacatca gcccaaccag taaattggtt
    38101 caatgcattc cattcactaa gaccgtgacg agaaaaaact aattttggca tgtttagctc
    38161 tccttttaag ataggtttat atttctgaaa ttttcagttc tgttttattg tacaattttt
    38221 tggaagagat ttccatcgaa aaattagata agattctatg agaaaacaag tagagaatat
    38281 aaaaaaacga acagtgccca cgcaactgtt cgtttttagg tattagatgc ataattgctc
    38341 gatttctttt tcaggtaaat tgatatattt ataacatgtt ccaactgaaa caccgcattt
    38401 tgaagaaata aattggatcg tttctttttt ttcataatag agacgtcgga tttttttgat
    38461 cgtttttgca tcgatttttg gtcttccgcc gatttttcct tttttacgag cttcatctaa
    38521 tccaactaat gtacgttctt tgatcaatgc gcactccatg tttgctaggt tttccattaa
    38581 ttggaaatag atttttccca tttcgcgcgt atcgattcct tcatcaagac taatcaagtg
    38641 cagcccgcga tctttgaata attgcgtgag ttctgttaat tgccgcgtag atttgcctaa
    38701 tcgatgaagt tggcaaatga ctagtgcatc gccttgttgc atgtcagcga tcactgactc
    38761 caaatgaaca gcagtagaat cattttgttc cacttcatat gtctcatgga aaatttcttg
    38821 acaaccaaag tcagataatt gatcaacctg agttgttaaa tcaacgtcat ttatggttgt
    38881 gcgtgcataa ccaataattt tcatggtgat tcctttctag cagtgatttt ctaactggat
    38941 ataacagtaa aaatgtagca taaagtacgt caaaaagata gttttttcgc aaattttccg
    39001 ctgtcttttt ttattggatg atcaagcagt ttttctttat ttacgacgga ttgcgtcaag
    39061 aatctcaacg cctttttctg agccgacaac tactttagaa accatgttta ggaaaagccc
    39121 atgttctact accccaacaa gttcatctaa ataggtagct aagctttctg gctgttcgat
    39181 gacttctaga tgcagatcaa tgatgtaatg accaccatct gtggttaaga cttctccgtt
    39241 ttcgtctgta cgcaagacgg gttggaatct tttttcttca aaaatatgaa gtagctgttg
    39301 ggagccataa gggatcactt caactgggag tgggaacttc ccaagtttat cgactaattt
    39361 agaagaatca acgatccaaa tcgtttcttt tgagtacgta gcgactattt tctcgaaaag
    39421 caaagcagcg ccgccgcctt tgatcccttg aaaatcagca ctgatttcat cagcaccgtc
    39481 tattgtcaaa tcgactacgg ggacttcatc aatactcttt aacggtattc ctaatttttc
    39541 cgcttgttct tttgtcgcat ttgaagtagt aactcctgtg atacgtaaac cttcttcacg
    39601 catacggcga ccaatctctt ctaccatata ataggcggtt gaaccggtcc cgagacctac
    39661 gatcatcccg tcctttacga atttcgcggc ttcaatgcca gctaattgtt ttaaattcat
    39721 ctttgcgtcc accttttttt agtttgagca tcgtgctttc ctcactattt tagcgtgatt
    39781 tacggtaaaa agataccatt cttttttatt ccaataaagc tttttcaaaa aaaattgcat
    39841 ctcttgttga catgtttttt cattcgtgat attctaacaa aggtgcttta tctacaggtt
    39901 tctgtgaaga aacgtgctga ctgtttatca aagcatattt gataaggatg cagacattgc
    39961 atttattttt tatcacaaaa aaagaaccac ctggatgtgt ggaactagac gcaaatcgtg
    40021 ggaaggagga aacaaggaat gcctacaatt aaccaattag tacgtaaacc tcgtaaatca
    40081 aaggtggaaa aatctaattc acctgctttg aacaaaggat ataacagctt taagaaaact
    40141 caaactaacg taaactcacc tcaaaaacgt ggggtagcaa ctcgtgtggg tacaatgaca
    40201 cctaaaaaac cgaactcagc tttacgtaaa tatgcacgtg ttcgtttgtc aaacttaatt
    40261 gaagttactg cttatatccc agggattggt cataacttac aagaacacag tgttgtatta
    40321 ttacgcggtg gtcgtgtaaa agacttacca ggggtacgtt accatatcgt tcgcggtgct
    40381 ttagatactg ctggtgttaa cgaccgtaaa caaagccgtt ctaaatacgg aactaaaaaa
    40441 cctaaagctt aattttaatt attaaacaaa tgaaacttgc ttctactata tagaagtaat
    40501 tactatgaac aatatttcgg aaggaggagt tacggatgcc acgtaaaggt cctgttgcaa
    40561 aacgtgatgt tttaccagat cctatttata actcaaaatt agtaactcgc ttgatcaacc
    40621 gtgtaatggt tgacggaaaa cgcgggattg cagctaacat tatctataat gcctttgact
    40681 tgatcaaaga atctacaggt aacgatccat tagaagtgtt tgaacaagca atgaaaaacg
    40741 ttcaacctgt tcttgaagtt aaagcacgtc gtgttggggg ttcaaactac caagtaccag
    40801 ttgaagttcg ccctgaacgc cgcgttactc taggtcttcg ttgggtagta aactacgctc
    40861 gcttgcgcgg tgaacacaca atggaagaac gcttagcaaa agaaatcatg gatgctgcaa
    40921 acaacacagg tgcttctgtt aaaaaacgtg aagacactca taaaatggct gatgccaacc
    40981 gtgcgtttgc tcactatcgc tggtaagatt ctctctgttt ggtcggcttt tataagtcga
    41041 cctcagatag tgtccttatt tttagcaact agatagtaaa gagaggagaa acaaggagaa
    41101 tgaccagaga attttcttta caaaacactc gtaatatcgg tatcatggcc cacatcgatg
    41161 ctggtaaaac gactgctact gaacgtatct tgtactatac tggtaaaatc cataaaattg
    41221 gtgaaactca tgaaggagct tcacaaatgg actggatgga acaagaacaa gaacgtggta
    41281 ttacgatcac ttctgctgct actacagcac aatggaaggg tcaccgaatc aacatcatcg
    41341 acacaccagg acacgtagac ttcacagttg aagttgaacg ttcattgcgt gtacttgatg
    41401 gtgctgtaac tgttcttgat gcacaatcag gtgttgaacc tcaaactgaa acagtttggc
    41461 gtcaagcaac aacttatggt gtacctcgta tcgtatttgc aaacaaaatg gacaagatcg
    41521 gtgctgactt cttatattca gtatcaactt tacatgaccg tttgcaagca aacgctcacc
    41581 caatccaatt accaattggt gcggaagacg acttcacagg aattatcgac cttgtaacaa
    41641 tgaaggctga aatgtataca aacgatcttg gaacagagat cgaagaaaca gaaattcctg
    41701 aagaataccg cgaattagct gaagaatggc gcgaaaaatt ggttgaagct gtagctgaaa
    41761 ctgatgaaga acttactttg aaatacttag aaggtgaaga aatcactgaa gctgagttaa
    41821 aagaaggtat ccgccgcgca acagttaacg tagaattcta cccagtacta tgtggttcag
    41881 catttaagaa caaaggggtt caattactat tggacgctgt tcttgattac ttgccatcac
    41941 cgttagatat cccagctatc aaagggattg accctaaaac tgatgaagaa gtagaacgtc
    42001 ctgcagacga cagcgctcct ttctcagctt tagcatttaa agttatgact gacccattcg
    42061 taggtcgttt aactttcttc cgtgtgtact ctggtgtttt acaatcaggt tcatacgtac
    42121 aaaacgcaac aaaaggcaaa cgtgaacgtg ttggtcgtat cctacagatg catgccaact
    42181 ctcgttcaga aatctctgaa gtttacgctg gagatatcgc tgctgctgtt ggtttgaaag
    42241 acacaactac tggggacaca ctatgtgatg aaaagagtct agttattctt gaatccatgg
    42301 aattcccaga accagttatc caagtcgcta ttgaacctaa atcaaaagct gaccaagata
    42361 aaatgggtgt ggctttacaa aaactatctg aagaagatcc tactttccgt gctgaaacaa
    42421 acgtggaaac aggcgaaaca atcatcgctg gtatgggtga acttcactta gatatcatcg
    42481 ttgaccgtat gcgtcgtgaa ttcaaagttg aagctaacgt aggtgcgcct caagtatctt
    42541 accgtgaaac tttccgtgct ggcactcaag ccgaaggtaa gtttgtacgt cagtctggtg
    42601 gtaaaggtca atacggtcac gtatggattg aatttacacc aaatgaagaa ggtgctggtt
    42661 tcgaatttga aaatgcgatc gtcggtgggg ttgttcctcg tgaatacatt ccagctgttg
    42721 aaactggttt gaaagatgct atggaaaatg gtgtcttagc tggctatcca ttagtagata
    42781 tcaaagctaa actttacgat ggttcatacc atgatgtcga ttcaaatgaa actgccttcc
    42841 gtgttgctgc ttctatggca ttacgtgcag cagctaagaa agctaatcca gtaatccttg
    42901 aaccaatcat ggctgtagaa gttgttatcc ctgaagatta tttaggtgat gttatgggtc
    42961 acgtaactgc tcgtcgtgga cgtgttgaag gtatggaagc tcgcgctggc ggccaacaag
    43021 ttgttcgtgc gatggttcca cttgctgaaa tgtttggtta tgctacaact cttcgttctg
    43081 ctactcaagg tcgtggtaca tttacaatga catttgacca ctacgaagat gtaccaaaat
    43141 cagtacaaga agaaatcatt aagaaaaacg gcggaaaagc tgaataattt cttgaaaccg
    43201 gatagtcctg caaagagatt atccaaagag actatatttt taatatagtt tcgtgtaaaa
    43261 taattatcga tgatatgggc atgtggtgta ccttgtgtac atcatatacc tatcagacaa
    43321 ataaaaaata tattgtattt ttaggaggac attttaaaat ggcaaaagaa aaatttgacc
    43381 gttctaaacc acacgttaac attggtacta tcggacacgt tgaccatggt aaaactacat
    43441 taacagctgc aatcacaact gtactatcta agaaaaacgg cggccaagct atggcttacg
    43501 atcaaatcga tggtgctcca gaagaacgcg aacgcggaat cacaatctca acagctcacg
    43561 ttgagtatga aacagataca cgccactacg ctcacgttga ctgcccagga cacgcggatt
    43621 acgttaaaaa catgatcact ggtgctgctc aaatggacgg agctatcttg gtagtttctg
    43681 ctgctgacgg cccaatgcct caaactcgtg aacacatcct attgtctcgt caagttggtg
    43741 ttccttacat cgttgtattc ttgaacaaag tagacatggt tgatgacgaa gaattactag
    43801 aattagttga aatggaagtt cgtgacctat taacagaata cgaattccct ggtgacgatg
    43861 ttcctgtagt tgctggatca gctttgaaag ctctagaagg cgacgcttca tacgaagaaa
    43921 aaattcttga attaatggct gcagttgacg aatacatccc aactccagaa cgtgacaacg
    43981 acaaaccatt catgatgcca gttgaagacg tgttctcaat tactggacgt ggtactgttg
    44041 ctacaggtcg tgttgaacgt ggacaagttc gcgttggtga cgaagttgaa gttgttggta
    44101 ttgctgaaga aacttcaaaa acaacagtta ctggtgttga aatgttccgt aaattgttag
    44161 actacgctga agctggagac aacattggtg ctttactacg tggtgttgca cgtgaagaca
    44221 tccaacgtgg acaagtttta gctaaaccag gtacaatcac acctcataca aaattctctg
    44281 cagaagtata cgtgttgaca aaagaagaag gtggacgtca tactccattc ttcactaact
    44341 accgtccaca attctacttc cgtacaactg acgtaacagg tgttgttgaa ttaccagaag
    44401 gaactgaaat ggttatgcct ggcgacaacg taacaatgga agttgaatta atccacccaa
    44461 tcgctatcga aaacggtact aaattctcaa tccgtgaagg cggacgtaca gttggtgccg
    44521 gtgtcgttac agaaatcaaa gcttaattca cttaagtttt aaagtaaagc aacatttatt
    44581 cggacgtaat cgctcggaac gaaggtctta ggatctttgt tccgagcttt tttatttatt
    44641 gcaggatcag gaaaaaagac aggagtatta taaatagaag aaacacgaaa taaaagagtc
    44701 agtattttct aaatgaaact ttatgaaaac aaaatgtttt ttacaagaaa aagccttgct
    44761 ttgtgagttt atatatatta taatgacaaa ggtgcgttta ctttagtgaa ttgcacagac
    44821 gtaatcagaa tgatttcgtc ggctaagaaa cgagaggttg cgacacgccc ggacgctttg
    44881 ccacgaacga gcgtgacgga aattttcgtg gagctatgtc tacttttcaa aataggcgaa
    44941 ggagggaaca agatggcaaa acaaaaaatt cgtatccgtt taaaagcgta tgaacaccgt
    45001 attttagatc aatcagcgga taaaatcgtg gaaactgcaa aaagaactgg agctagcgtg
    45061 tctggtccaa ttccattacc aactgaacgc agtctttaca caatcatccg tgcgactcat
    45121 aaatacaaag attcacgcga acaattcgaa atgcgtacac acaaacgtct tatcgacatt
    45181 gtgaacccaa caccaaaaac tgttgatgct ttgatgaagc tagacttacc atctggtgta
    45241 aacatcgaaa tcaaattata aaactaaaac aaaaataatg gaggtgtact catgaccaaa
    45301 ggaatcttag ggaaaaaagt gggaatgaca caaatcttca ctgaatctgg tgaattaatt
    45361 ccagtaactg ttgtagaagc tactccaaac gtagtactac aagtgaaaac aatggaaacg
    45421 gatggctacg aagctattca agttggttac caagatatgc gtgaagtttt atcaaacaaa
    45481 cctgcgaaag gtcatgttgc aaaagcaaac acggctccta agcgcttcat tcgtgaattc
    45541 aaaaatgttg agctaggaga atatgaagta ggaaaagaaa ttacagtaga tgttttccaa
    45601 gcaggagaca ttattgatgt aacaggtact acgaaaggta aaggattcca aggggttatc
    45661 aaacgccacg gacaaagccg cggaccaatg gctcacggtt ctcgttacca tcgtcgtcct
    45721 gggtcaatgg gtccagttgc acctaaccgt gtatttaaaa acaaacgtct tgctggccgt
    45781 atgggtggca accgcgtaac tatccaaaac ttggaagttg tacgtgtcga tgcagaaaga
    45841 aatgttatct tgatcaaagg taatgttcct ggagctaaaa aatctttaat tactatcaaa
    45901 tcagctgtga aagctaaata attgtaggaa gaaaggagga actaaggaat gccgaatgta
    45961 gcattattca aacaagatgg aagccaaaac ggtgaaatca cacttaacga agaaatcttc
    46021 ggaattgaac ctaatgaaag tgttgtttac gatgcaatcg taatgcaacg tgcgtcatta
    46081 agacaaggaa cacacgcggt taaaaaccgt agcgctgttc gcggcggcgg acgtaaacca
    46141 tggcgtcaaa aaggaacagg tcgtgcacgt caaggatcta tccgctcacc acaatggcgt
    46201 ggaggtggcg tagtctttgg accaacacca cgttcttaca gctacaaact tcctaaaaaa
    46261 gttcgtcgtt tagcaatgaa atctgtattg tcagaaaaag ttgctgaaaa caacttggta
    46321 gcaatcgaag gcttgaactt cgacgcacca aaaacaaaag aattcaaaca agttcttgct
    46381 aacttatcta tcgactctaa agtattggtt gttctagaaa aaggtaacga ctttgctgct
    46441 ttatcagcac gtaacttacc aaacgtttct gtagtaactt ctgataatgt gagtgtgcta
    46501 gacgttgtat caaatacaaa agtgttagca acacaaactg ctcttactca aattgaggag
    46561 gtgcttgcat aatgaactta ctagacgtaa tcaaacgccc agtgatcact gaaaaatcaa
    46621 tgcttgccat ggatgacaag aaatacactt ttgaagtgga cactcgcgca aacaaaactt
    46681 tagtaaaaca agcggtagaa gctgcttttg acgttaaagt caaaaacgtg aacatcgtga
    46741 acgtacgtgc gaaattcaaa cgtatgggca aatatgcagg atatacaaaa aaacgtcgca
    46801 aagcgatcgt tacattgact gaagattcaa aagaaatcca attattcgaa gctgctgaat
    46861 aagcactaat agataactca ttaaattagg agggaaaaac gtggcgatta aaaagtacaa
    46921 acctacctca aatggtcgtc gtaacatgac aggttctgat tttgctgaaa tcacaacatc
    46981 aacacctgaa aaatcattgt tacaaccatt gaaaaaccat gctggacgta acaacaacgg
    47041 ccgcatcact gtacgtcatc aaggtggcgg acacaaacgc caatatcgcg tgatcgactt
    47101 caaacgtaac aaagataacg ttgttgcaac tgttcaaacg atcgaatatg atccaaaccg
    47161 ttcagctaac atcgcgttag tacactatga agatggagtg aaagcttaca tcttagcacc
    47221 taaaggacta gaagtgggta tgaaacttgt ttcaggtcca gaagcagata tcaaagtcgg
    47281 aaatgctctt ccattagaaa acattccagt tggtactgtt atccacaaca ttgaaatgaa
    47341 acctggtaaa ggtggacaat tgatccgttc tgctggtaca agtgctcaag tacttggtaa
    47401 agaaggcaaa tacgtattga tccgcttgaa ctctggtgaa gttcgtatga tcttagctgc
    47461 atgccgtgct acaatcggtt ctgtaggtaa cgaacaacac gaattaatca acatcggtaa
    47521 agctggacgc tctcgttgga tgcgtaaacg cccaactgta cgtggtagcg taatgaaccc
    47581 taatgatcac ccacacggtg gtggtgaagg taaagctcct atcggacgta aagcaccagt
    47641 ttctccttgg ggtcaaccag ctcttggtta caaaactcgt aacaaaaaag ctaaatcaga
    47701 caaacttatt gttcgtcgtc gcaaaaataa ataattactt tgaccatgtg tcgcacattt
    47761 tgagaggagg ttcaccatgg gtcgtagttt aaagaaagga ccttttgtcg atgagcattt
    47821 aatgaaaaaa gttgaagctc aagcaggggt tgaaaagaaa aaagttatca aaacttggtc
    47881 acgccgttca acagttttcc caagttttgt tggatatacc atcgcagttt atgatggacg
    47941 taaacatgta ccagtttaca tccaagaaga catggtagga cacaaattag gtgaatttgc
    48001 acctacaaga acttatcgtg gacatgctgc tgacgataag aaaacgaaac gctaatttga
    48061 ggggaggata aatccaaatg gcagaacaaa tcacatcagc taaagcaact gcaaaaacag
    48121 ttcgcacttc acctcgaaaa gcccgtttag taattgacct tatcagaggt aaaagtgtcg
    48181 cagatgcaat ttcaatcttg aaattcacac caaacaaatc tgctggaatc attgaaaaag
    48241 tattgatgtc agcagttgcg aatgcagaaa ataactttga cttagatgtt gaaaacttgg
    48301 tagtaagcga agcttttgtt aacgaaggac ctacaatgaa acgtttccgt cctcgtgcaa
    48361 aaggatcagc ttctccaatc aacaaacgta caagtcatat cacggtagtc gtatcagaaa
    48421 aataaggagg gataatcagt gggtcaaaaa gtacatccaa ttggaatgcg tgtaggcatc
    48481 atccgcgact gggatgctaa atggtatgct gaaaaagagt atgctgagtt cttacacgaa
    48541 gatttaagaa tccgtaaatt tatttcaact aaacttgctg atgctgctgt atcaacagtt
    48601 gaaatcgaac gcgcaacagg tcgcgtaaac atttcaattc acacagctaa accaggtatg
    48661 gttattggta aaggcggttc tgaagtcgaa agcctaagaa aagaattaaa caaattaact
    48721 ggtaaaagaa tccatatcaa tatcgtggaa atcaaaaaac cagatctaga tgcaaaatta
    48781 gtaggtgaag gaatcgcacg tcaattagaa aaccgtgttg ctttccgtcg cgctcaaaaa
    48841 caagccatcc aacgctcaat gcgtgctggc gctcaaggga tcaaaactca agtatctggt
    48901 cgtctaaacg gagcagatat cgctcgttca gaaggatact cagaaggaac tgttcctctt
    48961 catactttac gtgcggacat tgattacgca tgggaagaag cagatacaac atacggaaaa
    49021 ctaggagtta aagtgtggat ctatcgtgga gaaattcttc caactaaaaa aaacactgag
    49081 aaaggaggga aataatcatg ttagtaccta aacgtgtaaa acaccgtcgt gaattccgcg
    49141 gaaaaatgcg cggggaagct aaaggcggaa aagaagtagc attcggtgaa tacggtttgc
    49201 aagctgttga ttcacattgg atcacaaacc gccaaatcga agctgctcgt atcgcaatga
    49261 ctcgttacat gaaacgtggt gggaaagtat ggattaaaat tttccctcac aaatcttata
    49321 ctgccaaagc aattggggta cgtatgggtt ctggtaaagg ggcacctgaa ggatgggttg
    49381 caccagtaaa acgtggtaaa atcatgtttg aaatcgcagg cgttcctgaa gaagtagctc
    49441 gtgaagcgtt acgtctagct tctcacaaat taccaatgaa aactaagatc gtaaaacgtg
    49501 aggaaatggg tggtgaatcg aatgaaggtt aaagaaatca gagaattaac cactgccgaa
    49561 atgcttgatc aagaaaaaca attaaaagaa gaattgttta atcttagatt ccaattagca
    49621 acaggtcaat tagaaaacac tgcacgtatt aaagaagtac gtaaatcgat tgcacgcatc
    49681 aaaactgtgt tgcgtgaaca agctaagtaa ttatggaagg aggccattaa gcgtatgact
    49741 gaaggaagaa atcaacgcaa agtttatcaa ggtcgcgtgg tttcagacaa aatggataaa
    49801 acaattaccg ttgctgtcga aacaaagaaa aaccacccta tctatggcaa acgcatgaac
    49861 tattctaaga aatacaaagt gcatgatgaa aacaacacag caaaagttgg cgacatcgtg
    49921 agaattatgg aaactcgtcc attatcagct acaaaacgtt tccgtttgtt ggaagtagtc
    49981 gaagaagcag ttattatcta ataacacgag attttcctat atagattgaa tgcaaaatct
    50041 gaaaggagga tacacaacgt gatccaagca gaaagtcgtt taaaagtcgc tgataactca
    50101 ggcgcacgtg aaattttgac gatcaaagtc cttggtggat ctggtcgtaa aactgctaac
    50161 atcggtgatg tgatcgttgc tacggttaaa caagcaacgc caggtggggt tgtcaaaaaa
    50221 ggtgacgtcg ttaaagccgt tatcgttcga acaaaatcag gagctcgtcg tacagacggt
    50281 tcatatatta aatttgatga aaatgctgca gtgattattc gtgatgataa aagccctcgt
    50341 ggaacacgta tctttgggcc agttgcacgt gaactacgtg aaaacaactt catgaagatc
    50401 gtttcactag caccagaagt tttataatct tgagacactt atcaaaggag gtgcgaaaca
    50461 gttatgtttg ttaaaaaagg cgataaagtt aaagttatca ctggaaaaga caaaaacaaa
    50521 gaaggcgttg tactagcagc gttcccgaaa aaagataaag ttattgtcga aggtgtaaat
    50581 gtcgttaaaa aacaccaaaa accttctcaa gctgctcctc aaggtggaat tgttgagatg
    50641 gaagcgccaa ttcatgtttc taacgtgatg gtggttgact ctactggtgt agctggccga
    50701 gttggctaca aagaagtaga cggcaaaaaa gtccgtgttt ctaaaaaaac cggtgaagtt
    50761 ttagataaat aaaagtttaa ggaaggaggg tcttactgaa tgaaccgcct aaaagaaaaa
    50821 tatcttaaag aagtaactcc atcattgatg gaaaaattta actatagctc tgttatgcaa
    50881 acacctaaag ttgaaaaaat cgtcatcaac atgggtgttg gtgatgcggt atcaaacgct
    50941 aaaaacttag ataaagcagt tgaagaatta actttgatca ctggtcaaaa accaatgatt
    51001 acaaaagcta aaaaatcaat cgctggattc cgtttacgtg aaggaatgcc aattggtgca
    51061 aaagttacat tgcgcggaga aagaatgtac gaattcttag acaaattggt ttctgtttca
    51121 ctaccacgtg tacgtgactt ccatggtgta agtaaaaaag cctttgacgg tcgtggaaac
    51181 tatactttag gtattaaaga acaattgatc ttcccagaag tagattatga tttagtagat
    51241 aaagtacgtg gtatggacat cgttattgta acaacagcaa actctgatga agaatctcgt
    51301 gagttgttga cacaattagg catgccattc caaaaataat taaaggaggc gaactacgtg
    51361 gctaaaaaat caatgattgc taaaaacaaa cgtcctgcaa aattttcaac acaagcttat
    51421 actcgttgcg aacgttgcgg acgtccacat tcagtttatc gtaagttcca tctttgccgt
    51481 atttgcttcc gcgaacttgc ctataaaggt caaattcccg gcgtgaagaa agctagctgg
    51541 taaaaagtaa attcgcataa gaaggaggta aaagatcaat ggtcatgaca gatccaattg
    51601 cagattttct aactcgtatc cgtaacgcaa acatggttaa acatgagtct ttagaagtac
    51661 ctgcatcaaa aattaaacgt gacatcgctg aaatcttgaa acgtgaaggt ttcgttcgtg
    51721 atgttgaata catcgaagat gacaaacaag gcgtgatccg tgttttccta aaatttggta
    51781 aaaacggcga acgtgttatc acaaacttaa aacgtatctc taaaccaggt ttgcgtgctt
    51841 atgtcaaagc tgacgaagta ccaaaagtat tgaacggttt aggtatcgca atcatttcga
    51901 cttctgaagg tgttgtcact gataaagaag ctcgtgaaaa aaatatcggc ggcgaagtta
    51961 tcgcttacgt atggtaatca agtagaatct acaaggaggt gtctttaagt gagccgtatc
    52021 ggaaataaag tcgttgttat ccctgaagga gtaacagtta ctcaagacgg aaacaacgtt
    52081 acagttaaag gaccaaaagg tgaattgact cgtacttttt cagcagatat caaaatgaat
    52141 atcgaaggaa acgaagtaac tttcactcgt ccaaacgaca gtaaagaaat gaaaacaatt
    52201 catggaacaa ctcgtgcgaa cttcaacaac atggttgtag gtgtcagcga aggtttccaa
    52261 aaagcgttag aactaatcgg ggttgggtac cgtgcacaat tacaaggatc aaaacttgta
    52321 ttgaacgttg gttactcaca tccagtagaa atcacaccac cagctggagt aactgttgaa
    52381 gtaccagcta acacacaagt aattgttaaa ggtgcgaaca aagaagaagt tggcgaatta
    52441 gctgcaaaca ttcgtggaac tcgtcctcca gaaccttata aaggtaaagg tattcgttat
    52501 gttggcgaat atgtacgccg taaagaaggt aaaactggta aataatcgtt tagaaaaatt
    52561 gcatagaagc cagcagcagg aaaaaggcat ttggctgaag tttaccttca aaaaaataca
    52621 tttttacttg tgccgcagct tctatttttc gaaacgtatt tactgcttga aatagtagta
    52681 caataaaaat aaagaggtga caattgtgat tacaaaacca gataagaaca aaacacgtca
    52741 aaagagacat cgtcgtgtac gtaacaatat ctctggtact gctgagcgcc cacgcttgaa
    52801 cgtttttcgt tctaacaaaa acatctacgc tcaaattatt gatgacgtag cgggtgtaac
    52861 gctagcaagt gcctctacct tggataaaga aatttcaggt ggaacaaaaa cagaagcagc
    52921 acaagctgtc ggtaaactag ttgctgaacg tgcagctgaa aaaggcatta aagtagtagt
    52981 ctttgaccgt ggtggatacc tttaccatgg ccgtgtgcaa gctttagctg aagctgctcg
    53041 cgaaaatgga ctagaatttt agaagaagga ggaataccat tcatggttta tatcgatcca
    53101 aaacatttgg aattagaaga ccgcgttgtt gcaattaacc gtgtaacaaa agttgttaaa
    53161 ggtggacgtc gtctacgttt tgctgcttta gttgttgtcg gtgacaaaaa cggacacgta
    53221 ggatttggta caggtaaagc tcaagaagtt cctgaagcaa tccgtaaagc aattgaagat
    53281 gcgaagaaaa acttagttga agtacctatg gttggttcaa caatcccaca cgaagtaatc
    53341 ggtgctttta gtggtggtag aatcctaatg aaacctgctg tagaaggttc tggggttgct
    53401 gctggtggac cagttcgtgc cgtattagaa ttagctgggg tagcagatat cacttctaaa
    53461 tctttaggct caaatacacc aatcaacgtt gttcgcgcaa cagttgaagg tttgaaacaa
    53521 ttgaaacgtg cagaagaagt tgcagaactt cgcggcaaat cagttgaaga attaatcgga
    53581 taaggaggac aacaataatg gctgaattaa aagttacttt aaaacgcagt attatcggac
    53641 gtcctcaaaa ccaacgcgat acagttaaag cgttaggtct tacaaagatt aacagttcag
    53701 tggttaagcc ttctaatgaa gcaattaaag gcatgatcaa tactgtttct cacctagtgg
    53761 acgttgaaga aatttaattt agaaaaatca taactagaac attaaggagg tgccaaacct
    53821 atgaaacttc atgaattaaa acctgctgaa ggttcacgcc aagtacgtaa ccgtgttggt
    53881 cgtggtactt catctggtaa cggaaaaact gccggacgcg gacaaaaagg acaaaaagct
    53941 cgttcaggcg gcggtgtgcg tttaggattt gaagggggac aaacaccatt gttccgtcgt
    54001 ttaccaaaac gaggattcac aaacgtgaac cgtaaagact atgcagtcat taatcttgat
    54061 gtattgaacc gctttgaaga cggagctgaa gtaactcctg ttgctttagt tgaagctgga
    54121 atcgtgaaaa acgaaaaagc tggaatcaaa gtattagcta atggggaact aaacaagaaa
    54181 ttaactgtga aagcagcaaa attctctaaa gcagctcaag aagcaattga agcggctggt
    54241 ggatcaatcg aggtgatcta atgtttagac tattaaaaga tgcttttaaa gtaaaagaca
    54301 ttagatcgaa aatcctattt actgtatttg tgttgtttgt atttcgccta ggtgcacata
    54361 ttactgtacc aggcgtaaat gctgcttcat tgcaaaacct ttcttctttg ccatttttca
    54421 acatgttgaa cttggtaagt ggtagtgcga tgcaaaactt ttccattttc tcaatggggg
    54481 tttcaccata cattactgct tctatcgtca ttcagcttct tcaaatggac atcgtgcctc
    54541 gatttgttga atggtcgaaa caaggggaag ttggtcgtaa aaaactgaat caagcgactc
    54601 gatatctgac attagtattg gcatttatcc aatctgtcgg tatcactgct ggattcaatc
    54661 aatacgctca attaggtttc gtgaataatc ctaacgtagc aacttacgta acgatcggtt
    54721 tgattctaac agccggtacg atgtttgtta cttggctagg agaacagatc acagaaaaag
    54781 gtatcggaaa tggcgtatca atgatcattt ttgcaggtat catttctaga ttgcctgaaa
    54841 gtatcagaga aatttatgaa gattacttta taaatattga tccttcagac atatggaaat
    54901 ctgctatttt tgtggccatt ttactagtag cggtcttgtt gatcgtgaca ttcgtaacat
    54961 ttttccaaca agctgaacgc aagatcccga tccaatatac gaaacgcgta gctggcgcgc
    55021 ctacaagcag ctatctgccg ttgaaagtaa atgcagctgg agttattcca gttatctttg
    55081 ctagttcgtt tattgctacg ccaaatgctg ttttacaagc attgagcggt agattcggtt
    55141 ctgaaaactg gtacaaagtg atgatggaga tctttaacta taatacagca cctggtgcta
    55201 cgatttatac gattctgatc gttgccttca ctttcttcta cgcctttgtt caagtaaacc
    55261 ctgagaaatt agcggaaaac ttgcaaaagc aaggaagtta tataccaagc gtacgccctg
    55321 gtaaggggac tgaagagtat gtctcaagat tactgatgcg tttaagtaca gttggtgcag
    55381 tcttccttgg tttagtggca ttgcttccaa tcattgctca aatggtttgg gatcttccac
    55441 aatcaatcgg attaggcggt acaagcttac tgatcgttat cggtgtagct ttagaaactg
    55501 cgaaacagtt agaaggctta atgctgaaac gtaaatatgt tggattcatt gagtaagaaa
    55561 gcgtgttgag gtttcccctc aacacacgtt ctcacacatt tattaggagg gaaaacaatg
    55621 aacctcattt taatggggct gccaggcgca ggtaaaggaa cacaagctga aaaaatcatt
    55681 gatgcttatg gtattccgca catctcaaca ggagatatgt tccgcgcagc gatgcaaaac
    55741 gaaacagctc ttggcctgga agcaaagtct tatatggata aaggtgcatt agttcctgat
    55801 gaagtaacaa atggaatcgt gaaagagcga ctagctgaac cagatacaga gaaaggcttc
    55861 ttattagatg gctttccacg tacgctagat caagcaaaag ctctggacgc aatgctaaaa
    55921 gatttgaata aaaaaattga tgctgtcatc gatatccatg ttggtgaaga aatcttggtc
    55981 gaacgtctag ccggccgatt tatctgcagc aattgtggag caacttacca taaaattttc
    56041 aaccctacaa aagttgaaga cacatgtgat cgttgcggtg ggcatgaatt ctatcaaaga
    56101 gaagatgata aacctgagac ggttaaaaat cgtctggcta tcaacatcaa aaatagtgaa
    56161 ccaatcttgg cttattataa agaacaaggt ttgctaaaca ctattgatgg tgctcgtgaa
    56221 atcgatgctg tatttgcaga tgtacaaaaa atcattgaaa aatagcacga ttgcccgtag
    56281 ccgacttgca ttatgcagtt actcttgtca agttcaataa attatgatag aatatgtcag
    56341 tccgacttct agagaatcct ctagatgatc cattttgaga attttgaggt gggaactgca
    56401 gtttccgcca ttttatcgtg tgaaaatgcg aaacaagtac aaggaggtac tgtgcgtggc
    56461 aaaagaagat atgattgaag tcgaaggtac agtcgtcgaa actttgccga atgcaatgtt
    56521 taaagttgaa ctagaaaacg gacaccaagt tcttgctact gtttcaggta aaattcgtat
    56581 gcattacatc cgtatcttac ctggtgacaa agtaacggtt gaattgtctc catacgatct
    56641 taaccgtggc cgtattactt atcgctttaa ataattgtac tccgtaaaac tacaggaggt
    56701 attatcatga aagtaagacc atcagtaaaa ccaatgtgcg aacattgtaa agtaattcgt
    56761 cgtaaaggac gcgttatggt gatttgccca gcaaatccaa aacataaaca acgtcaagga
    56821 taattggagg tgctataaat atggctcgta ttgcaggagt agatattcct cgtgataaac
    56881 gtgtagtagt ttcacttact tatatctatg gtattggtaa cactactgct aaaaagatct
    56941 tagctgatgc tggtgtatct gaagatgttc gcgttcgtga attaacgaat gaacaaacag
    57001 atgctatccg tgcagaagta gataaattaa aagttgaagg ggatcttcgt cgtgaagtga
    57061 acttgaacat caaacgtttg atggaaatcg gttcttaccg tggaatccgt catcgccgtg
    57121 gattgcctgt tcgtggacaa aacacgaaaa acaatgcacg tactcgtaaa ggcccagctc
    57181 gcgctatcgc tggcaagaaa aaataattct taagtgaagg aggttaaaac ttcatggcag
    57241 caaaaaaagt gaatcgtaaa cgccgtgtga agaagaatat agaagcaggt attgcacata
    57301 tccattctac attcaataac actatcatca tgatcactga tactcacgga aatgcattag
    57361 cgtggtcatc agctggttca ttaggtttca aaggaagcaa aaaatcaact ccttttgccg
    57421 ctcaaatggc agcagaaact gctacaaaag cagcaatgga acacggatta aagactgttg
    57481 aagtaacagt taaaggacct ggttctggac gtgaagcagc aattcgttca ttacaagcta
    57541 caggtttaga agtgactgca attcgtgacg tgactccagt tcctcataat ggtgcccgcc
    57601 ctccaaaacg ccgtcgtgtt taatgagtgc cgctcatttt gagttttatc agtaacgtca
    57661 ttgaacaaga cacttttcgt tttgaaaggg gtaaagataa gaatgattga gttcgaaaaa
    57721 ccaagaatcg caaaaattga tgaagaaaaa gattatggca agttcatcgt tgaacctctt
    57781 gaaagagggt atgggactac tttagggaat tccctacgtc gtattttatt atcttctttg
    57841 ccaggtgctg ccatcactaa tattcaaatc gatggtgtac tgcatgaatt ctctaccatc
    57901 aaaggtgtta gagaagacgt cactcaaatc atcttgaaca ttaaaggctt agcgctgaaa
    57961 atgtatggcc aagaagaaaa aacccttgaa atcgatatta ccggacctgc tacagtaact
    58021 gctggcgata ttatcgttga tagtgatgta gaaattctta acaaagatat gtacatctgt
    58081 agtgtctctg aaggagctac gttccatgct cgcttaacag tgaaacctgg acgtggttat
    58141 gttcaagcag atgaaaataa aaaagaagat atgccaattg gcgttcttcc agtcgattca
    58201 atctacacac ctgttcgtcg tgtgaactat caagttgaga acacacgtgt tggacaccgt
    58261 gaagattttg ataaattgac gatggagatt tggacagatg gttcaattga accgttggaa
    58321 gcaatgagtt tgtctgcgaa aatcatgact gaacatttgg atatttttgt gaacttaact
    58381 gatgaagcaa aaaatgctga aatcatggtc gaaaaagaag aaacacaaaa agaaaaaatg
    58441 ttggaaatga cgatcgaaga gttagacttg tctgttcgct cttacaattg tttgaaacgt
    58501 gcaggaatca atactgtaca agaacttaca aataaatctg agcctgaaat gatcaaagtc
    58561 cgtaacttag gacgtaaatc attagaagaa gttaaagcaa aattgcacga cttaggttta
    58621 ggtttacgta aagaagatta aaacctttta cgaaggaggg aaaccaacgt gagttatcgt
    58681 aaactaggac gcacatctag ccaacgtaaa gcgatgttgc gtgatttaac aactgattta
    58741 ttaatcaacg aacgtattgt gactactgaa gctcgtgcga aagaagttcg ctcaactgca
    58801 gaaaaaatga tcactttagg taaacgcgga gatttgcatg cacgtcgtca agctgcggct
    58861 ttcgtacgta atgaagttgc cagcgtgcgt gaagaaaatg aggacatcgt cattgaatca
    58921 gctttacaaa aactgttcaa cgatattgca cctcgttacg cagaacgtca aggcggatac
    58981 acacgcattt tgaagacaga accaagacgc ggtgatggtg caccaatggt tgtcttagaa
    59041 cttgtctaaa atcacactaa taacatcact ttatagatga ttcttttaga gtgttatgat
    59101 gttggaagat atttttccga gtctagctca gcgctgctcc tcaagcgaat atcgcttggg
    59161 gagtaagcac tcatcataaa gtgttttttt ataccttcaa ttacctgtca tgacagatat
    59221 gtttgaaggc ataaaaaaac attttaagcg agaaataatt gaaaattttg tctttttttg
    59281 atagtgttag taggaacttt aggatgaaga aggagtaatc atggagccaa ttattgaatt
    59341 agaaaagata aattataaat accagccaga tgatcttcgc cccgcattga aagatgtctc
    59401 ctttacaatt gataaaggtg agtggatcgc tattattgga cacaatggtt caggaaaatc
    59461 gacacttgcc aaaacgatca atggattgct tctgccagaa tcagggatcg tgaaagtggg
    59521 aaatcaaata ttggatgaag aaaatatttg gacgatccga cagatggttg gaatggtttt
    59581 tcaaaatcca gacaatcagt ttgttggttc gacagtagaa gatgacgttg cttttggtct
    59641 tgaaaatcaa gggattccca gagaagaaat gctagtgcgt gtgaaagatg cacttgagaa
    59701 agttagaatg gctgagtttg cttcacgcga gcctgctcgt ttatcaggag ggcaaaaaca
    59761 acgtgttgcc attgccggcg tggttgcctt acgacctgat atcattattt tagatgaagc
    59821 aaccagtatg ctagatccag aaggtcgtga agaagtgatc tctacgatca agaagatcaa
    59881 agaagaaagt caattgaccg ttatatctat cactcatgat attgatgaag cagctaatgc
    59941 caatcggata ctagtgatga gacaaggcga acttgtccgt gaaggtacac caaaagaaat
    60001 tttttctgct ggtcctgaac tgatcgactt aggtctagat ctaccatttc ctgaaaaact
    60061 gaagagcgca ctgaaagaac gtggggttga tgtgcccagt gaatatatga cagaagaaag
    60121 gatggtggat tggttatgga catccgtttt gaacaagtag acttcactta tcagccgaat
    60181 acaccatttg aacaaagagc cttatttgac atcaatatga cgatcaaaga aaacagttat
    60241 actgcattag tagggcatac cggaagcggg aaatcaacct tacttcagca tttgaatgcg
    60301 cttgttaagc caacaagcgg tacagtccat attggagaac gagatattca gccggatacg
    60361 gataataaga atttaaagcc catccgaaaa aaagttggca tcgtctttca gtttccagaa
    60421 gcacagctat tcgaagaaac ggtagcaaaa gacattgctt tcggtcctaa aaactttggt
    60481 gtcagcgaag aagaagcact agtcctagca aaagaaacat tagaacaagt tgggctggat
    60541 gaaagctatt tggaacgttc gccatttgaa ctttcaggag ggcaaatgcg tagagtagca
    60601 atcgctggtg tgcttgccat gaggccggaa gtacttgtat tggatgaacc aacggcagga
    60661 cttgatcccc agggcagaaa agaaatgatg gagatgtttt ggcgtcttca taaggaacag
    60721 cagatcacta ttgtattagt tacgcattta atggatgatg tagccaattt tgcagattat
    60781 gtctatgtgt tggaaaaggg acgaatcgtt aatagcgggg agccgcaaga ggtctttcaa
    60841 aacattgaat ggctaaaaga aaaacaacta ggcgtaccta ctgccaccga gtttgcagaa
    60901 gaattaatgg ctaaagggat gaactttgct accttgcctt tgacagctga agaattagca
    60961 gacgctatcg tccattatgc tggaggaaat gcccatgatg aataaattga tatttggtcg
    61021 ttatatgcct ggagattcct tgatccatcg attggatccc cgagctaaat tattagccag
    61081 tttttatttt atcggaatca tttttttagc aaataattgg gaaacgtacc ttttgttggc
    61141 atttttcaca ttactttctg tcttcttgtc aaaagtagat ttgaaatttt ttatccgagg
    61201 cattcgccca ttgatctggc taatcctctt cactgtagct ttgcaggtct tgtttacaag
    61261 tggcggagaa acttattgga gttggggtgt tttccatatc actgaatttg gtgtgatgaa
    61321 cggcctcttt attttctgtc gattcgtgtt gatcattttt atgtcgactc tactcacgct
    61381 tactacaccg cctttggaat tatcggatgc gattgagtac ttgcttcgtc cattgaaagc
    61441 cgtacggttc ccagtccacg aaatttcatt gatgctgtcg attgctcttc gttttgtgcc
    61501 tacattgatg gacgaaacag aaaagatcat gaacgctcag cgcgctcgcg gtgttgattt
    61561 tggtgaagga aacctagttc agaaaatgaa agcagtcatt cctttgctga ttcctttatt
    61621 tgtcagcagc ttcaaccgtg cggaagatct tgcgactgct atggaagcaa gaggctacaa
    61681 aggtggggaa ggaagaacga aatatcgtgt attgcattgg cataatagag acacgatggt
    61741 tatcattgct tttgtattat taactgtgct actgatcttt ttaagaggat aaacgttcag
    61801 tgggccgcta tctattcttt tcttgctgat ctgtttgcaa gaaaggatgc aagcagtgta
    61861 tgacaagaaa tattagggtc tgtggcagac taaggtcaca ggcctctttc ttttatctga
    61921 aaagaaagaa cgaaaaaat
//
LOCUS       DADLIO010000008        61527 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.008, whole genome shotgun sequence.
ACCESSION   DADLIO010000008 DADLIO010000000
VERSION     DADLIO010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 61527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61527
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.008"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(<1..2327)
                     /gene="esp"
                     /locus_tag="JOX41_000635"
     CDS             complement(<1..2327)
                     /gene="esp"
                     /locus_tag="JOX41_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HAY6448402.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKYFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAG"
     gene            complement(2944..3378)
                     /locus_tag="JOX41_000636"
     CDS             complement(2944..3378)
                     /locus_tag="JOX41_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448403.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            complement(3395..4600)
                     /locus_tag="JOX41_000637"
     CDS             complement(3395..4600)
                     /locus_tag="JOX41_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HAY6448404.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            5294..5680
                     /locus_tag="JOX41_000638"
     CDS             5294..5680
                     /locus_tag="JOX41_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAY6448405.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            5774..5965
                     /locus_tag="JOX41_000639"
     CDS             5774..5965
                     /locus_tag="JOX41_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAY6448406.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            6479..6811
                     /locus_tag="JOX41_000640"
     CDS             6479..6811
                     /locus_tag="JOX41_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAY6448407.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            7107..7262
                     /locus_tag="JOX41_000641"
     CDS             7107..7262
                     /locus_tag="JOX41_000641"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HAY6448408.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            7538..8878
                     /locus_tag="JOX41_000642"
                     /pseudo
     CDS             7538..8878
                     /locus_tag="JOX41_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(9119..10735)
                     /locus_tag="JOX41_000643"
     CDS             complement(9119..10735)
                     /locus_tag="JOX41_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HAY6448409.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            10853..11071
                     /locus_tag="JOX41_000644"
     CDS             10853..11071
                     /locus_tag="JOX41_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAY6448410.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            11266..11727
                     /locus_tag="JOX41_000645"
     CDS             11266..11727
                     /locus_tag="JOX41_000645"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAY6448411.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(11920..12159)
                     /locus_tag="JOX41_000646"
     CDS             complement(11920..12159)
                     /locus_tag="JOX41_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448412.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(12183..13706)
                     /locus_tag="JOX41_000647"
     CDS             complement(12183..13706)
                     /locus_tag="JOX41_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HAY6448413.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            complement(13724..13846)
                     /locus_tag="JOX41_000648"
     CDS             complement(13724..13846)
                     /locus_tag="JOX41_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HAY6448414.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            complement(13876..14859)
                     /locus_tag="JOX41_000649"
     CDS             complement(13876..14859)
                     /locus_tag="JOX41_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HAY6448415.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(14883..15032)
                     /gene="rpmG"
                     /locus_tag="JOX41_000650"
     CDS             complement(14883..15032)
                     /gene="rpmG"
                     /locus_tag="JOX41_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003550836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAY6448416.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(15053..15430)
                     /locus_tag="JOX41_000651"
     CDS             complement(15053..15430)
                     /locus_tag="JOX41_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448417.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(15462..15641)
                     /gene="rpmF"
                     /locus_tag="JOX41_000652"
     CDS             complement(15462..15641)
                     /gene="rpmF"
                     /locus_tag="JOX41_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HAY6448418.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(15656..15925)
                     /gene="rpsN"
                     /locus_tag="JOX41_000653"
     CDS             complement(15656..15925)
                     /gene="rpsN"
                     /locus_tag="JOX41_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HAY6448419.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(16448..18220)
                     /locus_tag="JOX41_000654"
     CDS             complement(16448..18220)
                     /locus_tag="JOX41_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002841847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6448420.1"
                     /translation="MRMQMIGGLTMKSFYKNKFALSDQGAEALTKASISSFFVYCINM
                     VPAFIIMMLIDELVLENTKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLR
                     VQIADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVM
                     LLVGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEI
                     NSFNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLL
                     TGEVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSP
                     LKSFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDY
                     DEGCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAA
                     RLANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLD
                     AENEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSE
                     IYKNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(18174..19928)
                     /locus_tag="JOX41_000655"
     CDS             complement(18174..19928)
                     /locus_tag="JOX41_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6448421.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(20038..20607)
                     /locus_tag="JOX41_000656"
     CDS             complement(20038..20607)
                     /locus_tag="JOX41_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HAY6448422.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(20625..22049)
                     /locus_tag="JOX41_000657"
     CDS             complement(20625..22049)
                     /locus_tag="JOX41_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAY6448423.1"
                     /translation="MKELFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSG
                     KSTLLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTN
                     TTSELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLS
                     LNSKLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVK
                     NRTVKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDIN
                     FDVKVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQF
                     FTESVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSK
                     TNLFLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGG
                     IKKDIKLRVEDSTLIEQIFNDITK"
     gene            complement(22051..22719)
                     /locus_tag="JOX41_000658"
     CDS             complement(22051..22719)
                     /locus_tag="JOX41_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HAY6448424.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFATSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(22849..23433)
                     /locus_tag="JOX41_000659"
     CDS             complement(22849..23433)
                     /locus_tag="JOX41_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAY6448425.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLI
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(23764..23997)
                     /locus_tag="JOX41_000660"
     CDS             complement(23764..23997)
                     /locus_tag="JOX41_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HAY6448426.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(24012..24962)
                     /locus_tag="JOX41_000661"
     CDS             complement(24012..24962)
                     /locus_tag="JOX41_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HAY6448427.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSINSKDKDKVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(24959..25801)
                     /locus_tag="JOX41_000662"
     CDS             complement(24959..25801)
                     /locus_tag="JOX41_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAY6448428.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAIGMNVSFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGASSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERSL"
     gene            complement(25803..26522)
                     /locus_tag="JOX41_000663"
     CDS             complement(25803..26522)
                     /locus_tag="JOX41_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAY6448429.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKKLKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGE"
     gene            27214..27360
                     /locus_tag="JOX41_000664"
     CDS             27214..27360
                     /locus_tag="JOX41_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAY6448430.1"
                     /translation="MNKKQTCAFLGIDNNTLDKWIRIYNFPVIRVGGVVRFDVEDIKD
                     FMNT"
     gene            27432..28658
                     /locus_tag="JOX41_000665"
     CDS             27432..28658
                     /locus_tag="JOX41_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAY6448431.1"
                     /translation="MPTKLSNGKYKTNLRYPKRFKEITGIASEKYQKTFPNRQLAIKA
                     ENDMKKKIEKVLREENANSLELKGKITFKKFYESKWLPRYELGQTIRSNRPPSDITIS
                     NTKDIFRLHILPMFGEYAMNYLNINTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQSITAPKKNALEEKRIQEGKQALSSKELTNWIEAVNDDFNNHLL
                     TFHDYTLFMITLYLGDRKSETYALQWKYIDFEKQTVRLKHTLDKYQRKKFTKGRKDTV
                     IQVPEVVMTLLSEWKSVQADQLLKLKIKQTLDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPDLVHLSPHKLRHTYATIARQGGADMNQISNALTHSDISTTKIYVNTPDIV
                     DKAVFEAFQRGLNKCD"
     gene            complement(28746..29138)
                     /gene="rpsI"
                     /locus_tag="JOX41_000666"
     CDS             complement(28746..29138)
                     /gene="rpsI"
                     /locus_tag="JOX41_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HAY6448432.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(29154..29597)
                     /gene="rplM"
                     /locus_tag="JOX41_000667"
     CDS             complement(29154..29597)
                     /gene="rplM"
                     /locus_tag="JOX41_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HAY6448433.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(30116..30583)
                     /locus_tag="JOX41_000668"
     CDS             complement(30116..30583)
                     /locus_tag="JOX41_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HAY6448434.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(30703..32241)
                     /locus_tag="JOX41_000669"
     CDS             complement(30703..32241)
                     /locus_tag="JOX41_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HAY6448435.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            32321..33007
                     /locus_tag="JOX41_000670"
     CDS             32321..33007
                     /locus_tag="JOX41_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HAY6448436.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(33208..33735)
                     /gene="msrA"
                     /locus_tag="JOX41_000671"
     CDS             complement(33208..33735)
                     /gene="msrA"
                     /locus_tag="JOX41_000671"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAY6448437.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(33819..34496)
                     /gene="pgmB"
                     /locus_tag="JOX41_000672"
     CDS             complement(33819..34496)
                     /gene="pgmB"
                     /locus_tag="JOX41_000672"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAY6448438.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(34493..35623)
                     /locus_tag="JOX41_000673"
     CDS             complement(34493..35623)
                     /locus_tag="JOX41_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAY6448439.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(35623..37806)
                     /locus_tag="JOX41_000674"
     CDS             complement(35623..37806)
                     /locus_tag="JOX41_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HAY6448440.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(37803..38828)
                     /locus_tag="JOX41_000675"
     CDS             complement(37803..38828)
                     /locus_tag="JOX41_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAY6448441.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(38873..39700)
                     /locus_tag="JOX41_000676"
     CDS             complement(38873..39700)
                     /locus_tag="JOX41_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAY6448442.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(39697..40764)
                     /locus_tag="JOX41_000677"
     CDS             complement(39697..40764)
                     /locus_tag="JOX41_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HAY6448443.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(40790..41626)
                     /locus_tag="JOX41_000678"
     CDS             complement(40790..41626)
                     /locus_tag="JOX41_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAY6448444.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(41623..42492)
                     /locus_tag="JOX41_000679"
     CDS             complement(41623..42492)
                     /locus_tag="JOX41_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAY6448445.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(42562..43845)
                     /locus_tag="JOX41_000680"
     CDS             complement(42562..43845)
                     /locus_tag="JOX41_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAY6448446.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(43859..45544)
                     /locus_tag="JOX41_000681"
     CDS             complement(43859..45544)
                     /locus_tag="JOX41_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HAY6448447.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGTRVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            45819..46844
                     /locus_tag="JOX41_000682"
     CDS             45819..46844
                     /locus_tag="JOX41_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAY6448448.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(47439..51092)
                     /gene="rpoC"
                     /locus_tag="JOX41_000683"
     CDS             complement(47439..51092)
                     /gene="rpoC"
                     /locus_tag="JOX41_000683"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HAY6448449.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVET
                     ITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISN
                     FTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPE
                     TNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVIT
                     EVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSI
                     DPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTD
                     ILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRV
                     LTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEA
                     QMAAEDAMNNQTK"
     gene            complement(51171..54788)
                     /gene="rpoB"
                     /locus_tag="JOX41_000684"
     CDS             complement(51171..54788)
                     /gene="rpoB"
                     /locus_tag="JOX41_000684"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HAY6448450.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            55516..56484
                     /locus_tag="JOX41_000685"
     CDS             55516..56484
                     /locus_tag="JOX41_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAY6448451.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            56502..57407
                     /locus_tag="JOX41_000686"
     CDS             56502..57407
                     /locus_tag="JOX41_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAY6448452.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            57404..58210
                     /locus_tag="JOX41_000687"
     CDS             57404..58210
                     /locus_tag="JOX41_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAY6448453.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            58367..59335
                     /locus_tag="JOX41_000688"
     CDS             58367..59335
                     /locus_tag="JOX41_000688"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HAY6448454.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDVKLAAAQGD
                     SVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTIIAASACVK
                     AIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLNFSVPQNH
                     FPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKSFVLGKTV
                     SFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(59652..60176)
                     /locus_tag="JOX41_000689"
     CDS             complement(59652..60176)
                     /locus_tag="JOX41_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinB family protein"
                     /protein_id="HAY6448455.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            60463..>61527
                     /gene="scm"
                     /locus_tag="JOX41_000690"
     CDS             60463..>61527
                     /gene="scm"
                     /locus_tag="JOX41_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HAY6448456.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSS"
BASE COUNT        18661 a        12347 c        10307 g        20212 t
ORIGIN      
        1 cctgcggtga aggttacttt gtggtagcct gcaggaatgt tttctcctgg attttcataa
       61 atatctttac ttacagttac tgctaaatcg gtcgtgccta cagaaccatc ttggtaaaca
      121 attttaatag gaattgttcc agtaatcggc tccgattctc ctacaccttt agctggagtg
      181 aatgtaacaa taccagtgtt tgcatcaaca cttgcattac cgaagtactt attatagaca
      241 tctgaaattg aaaaggcatc tttagctaaa ggaacatctg gtttatcaaa tgtaggtttt
      301 ccactttgaa ctgtcgtttc tggagttgtt gttataggta cgtatgttgc atcattttcc
      361 atagcttgag aagcttttac agcaaactct acatccacgt cgaaagttcg atttccgatc
      421 ttaacagtta caataccttt cgtactatca gtaacgttag aagtatcagg ctctgttttc
      481 catgaatact ctgcatcttc aggtaagttt ttattattcc gaattgattc tttagcatct
      541 ggtttaaatc caactaccac ggtttgttta tcaaccgctt ttggtgattc cttaataacg
      601 gttgaacctt cttctggttt atcaaaacct ggagaaacga tttggatttt taattcatct
      661 ttcgcgatta atttacttga atctacaccc gtaaattcaa attctacagt atctgaaatt
      721 ggagccccat ctttttcatt tggagcgata gttttttctg ctaatacagt accttcttta
      781 tcaacaagtt gggctttgtg acctgttccc gctaactcgt ggatgaatac tttcccctta
      841 actgttgtgt caacatcata tacttcttct aattcaggtt tcccgatata tggattcgtg
      901 tctccgctct cttctttatc gtcagggttt ccatcaccat caatatcttg caaataataa
      961 taacctgttc cataagtgtt ctggattaat tttttattcg tatccgacaa ccaagaatca
     1021 aagatgaaat cttcaccaaa tggtttattt tcttcaactt gtgctgttgc tttcatatct
     1081 tctaagattt catctaatgg cttagtcaat tgtaaaacat atcgaataac gactggacgt
     1141 ggacttgcat tagcaaaatc gataagttta gttaaatcat tattagttat tgaacctatg
     1201 ccataatttt catgaccttc ccgtcgctcg attgctaaat cagctacttt tgttccggat
     1261 tcaaacgaaa catcatatgt tactttgtca gcctgaacca tgtgcatctg tatacccgct
     1321 acatatggaa ctaatcgttc atcaattttg taattagcat accaaggcgt gccctttgcg
     1381 gaagatgaat atgagaaatt ataatttttc gttaacttat gatctaagat tatagctcca
     1441 ttagcacctg tggatcctga accatctttt gtttgagtat taggtttctc atattttgca
     1501 cttactgatc catgtttaaa ctggtcagga ttattttcag atacatctaa gctattatag
     1561 aaatcatctg aatctgttaa aaagtagccc gtactatcaa tacccggtac aattttatca
     1621 tcgtcttgat gacttaccaa gtagattcga tacattaaac gatcggtctt gagattgtct
     1681 atgcctatct ctttaaaaat ttcatctagg ctcttttcaa acgtaattac cccattagga
     1741 gcggtttgcg tatcggttgt ttctgcccca gcaaataatc catcacttgc acgaatataa
     1801 ttgaccttcc aaatatttgt aggtctaccc agcgaatcat taattcttac aaaggtccgt
     1861 ctagaagatc caattccttt ctttggatcg acctgaattt tttctacata tttagctaat
     1921 cgttcatcta attgaagacg gatttcccag tttttagttg atgctgcaat attatgtttt
     1981 ccgtaaactt caaatccaat tgtattgcct tttagtgtgt ctccagttag ttcttgagga
     2041 ctaaattgta aatccgaaaa gttataattt ttcgtataac caggattctc ctgaaaagta
     2101 ttccccgaag ctactttgtc acctacttgt acggagctta tcgctgtttc aagtgggctg
     2161 cttggagaaa tttcatcttg tgctttaact agttcagttg ttcccaagac aagaccaaca
     2221 ccaatcaaaa cagatgcaac cccaacactt aattttttga tactgtactt caatactcgt
     2281 ttctttgttt tttctagaaa tactctctta ttattcttgc taaccattat tcaaatcaac
     2341 tcccttaata attactttcc tagtaagaat aaaagataaa tctgatacgt attattcaca
     2401 gaataggaat cttactaacc ttatgttaac taatttactt agagaatttc atgaacatta
     2461 caacaaaaaa agtacatttc ttcatgtttt tttcggatat ttgtgctttt taaccattca
     2521 gcagctgaaa acatataaaa agatatgtat gtattctttc tgaaattaag ttcatttcta
     2581 tgcgatgaag catgttttca aaatattacc ctttcttaga ttaaacttca gagtattcaa
     2641 ataacggaat aaggagcctt atcccgcatt actgaatgag actgtgacat aagtaaaaag
     2701 gtgacttcaa attccttctt cggaatttga aatcaccttc tttataatta taaagtatcg
     2761 gtttcacagc atttctgaat gattcctaga atcttaaacg aatgattgga gttatcaaca
     2821 ttttttcact cgtttttagc gaaacaaaaa atgacatttg tcacagcctc attaaattat
     2881 tgattctttt tctttataat tgaattgtcc atatttaaag tgtctagtac tctacatgaa
     2941 taattaattg ctttcactca aatacttata atctattaac ttgtagttgt ttaacttttc
     3001 tgaaaaagtt agacccacgt aataatcttc ccagctttct ctttcaatta actgatccaa
     3061 tttttgataa tccataaatt catcatgtat caaaaagaat aaataacttg atattttagc
     3121 atctagctta atcagattaa ataatgtttg tttaaaattg ctaccattaa tatgactgat
     3181 agattctcta gcttcttcac ataaactttt tactttatta attactactt tgtcatattc
     3241 atttaacaca ctattattac cattacttag acgctcagat tctacgaaac aactcaaatc
     3301 agaaatttcc caaaaaaatt ttttgttaaa atccaatttc ctcaactcct ccaaactacg
     3361 taaatgatat agtctcataa taaaataaaa cctctcagct aatgttgttg aaattgtcca
     3421 ctaaacctaa ttgatattgc ttaggagata cacctgcgta ctttttgaat actctcgaaa
     3481 agtgtgaaga atctgaaaat cctaaaccta aagaaacttc actgatagta tggtttgatt
     3541 tcaacattat tttagccgta gaaatttttc gcttagagat ataattataa atcgtaatat
     3601 gcatttcatt cttaaagctt tctcttaatt tagtttcact tacagaaaaa taattagcta
     3661 tttcctttac agtaattctt ttatagatat ttaagccgat gaattgaacg acagaagaaa
     3721 ttaagggaga aagatgctct atcttagttt ttccgatttc cttagtataa taaacaatcc
     3781 cagaatccct cacttttaag acctcaggta acgatacagc taattcgttt tcttgtatca
     3841 aagcatctct actttgatac gcttctatta tatccattcc taatgttata gacgtttgtg
     3901 ctaacttttc aaaaacaatg atagaataat ttttttcaga ccgaatcgta tctccactaa
     3961 cacttggaat tattccatta ctcagattaa aaaccatgtt ttctaaattt cgaatatctc
     4021 catttttaac atattccagt attttatttt cataaagaaa cagatatatt tctggatcgt
     4081 aattttgtga taacagatta tctattttga tttgctcgat agttttactt agattttctg
     4141 tatattcaat taacggttca tggaatagat cttctatttt tccagtaaaa aaataatgaa
     4201 ctaaaatcag aatatctcga atgtctccta aagaatacaa agtcaaattt tgcaatgaat
     4261 tatagagtcg ttctctatca gccattgcaa cattcaaatt gttcattttt agtttaaaaa
     4321 aaactttatc aatattattt gctctaaatg gaccaaataa gtaatatctg gttttaaaca
     4381 tgtatagaag aaacatctca ttaaaatcac cagtaaagaa atggaaatct ttagtttttt
     4441 taatattatc agttagtaac tttttataat cataaaaaaa ataagtagtt ctatctgagc
     4501 gatactcttt tataatactg aattcggaat taaaaaccac gataggtaac tttaaacaaa
     4561 catgaagaga ctttaataag acttctttat ctgaaaacac ttttgtttct ctctttcctt
     4621 tctacatcat taaatagtat tttatacgtt atctaaaata ctattcctct gtcaaaataa
     4681 gctaacttac ttcattataa aatatccact tatcgctttc atgtatattc caccgtaaaa
     4741 agtacatttt atcaccgaga actcatcatt tttcatcatg atgaatacta tttacatata
     4801 tctagttcaa agacaataat tattatgatc cgttattatc taagcactat acagataata
     4861 ggaatttttc gtttctaaat attccaattt gggaatccaa taaaaatttt cgttcaaata
     4921 cgtgtctatt cgaactcttt tctagttgtt aattatgaag ggggaagaaa taaaaaatac
     4981 aatctataca cgaataagaa tattatccaa aaggaggttt tagaaaagat ttattatacg
     5041 taaaaagctc aagacatttt cttagccata aggacatgtt tgatatttaa gaagatatat
     5101 gaattttctt ttctaagtat aaagataact atccattatc aactaaaaaa acatttttga
     5161 aaataaacat cagcagtcct atcaatgcat gtgagcttat agaagttatt cgcagcgcag
     5221 cataattgca ttagcttctt ttcgtgtttt ttgcctcttt tccctttaaa tcttaatgga
     5281 ggaggtgtgc aatatgtcag ataacgacga acgcgtaaat gcccagttga ttcgattctt
     5341 tgaaaaggtc attttgaaca ccgctaatac ttattataaa aaacaagaag aaattcaaaa
     5401 acatgaacaa cttgatcaac tcccaccata tttgtttact aaagatacta taaaatttaa
     5461 acaaccgatt aatgttttaa atgtgactct ccttgttgaa gatataaaat tagcaaaaat
     5521 ccttcctttg ttgaaagaac ctgaacaaat ttttcttatc gaaaaattta tctttgataa
     5581 aactgataaa gaaattggaa aggttctggg gattacaaga cagggtgcga caaatttaaa
     5641 acatcgactt tacaaaaaaa ttcaaaaaat gctggtttaa tatctgcata ataactaatt
     5701 ttgtatgctt ctttgctcgt tctcctcctt cccaaagaaa tagattataa gtccatggga
     5761 agaaggtaga tttatgaatt ctttaaaaga agatttcatt ttagcaaagg ctggaaatga
     5821 agaagctgtt gaggcaattc tcaaaagatt tagctctttg attcataagc aatcctggag
     5881 aactggaaaa tatgatcaag attgttatca agaatgtatg cttgcaatat atctagctat
     5941 ctcgaaattc gaaattaaag aataactcaa ctaagggagt ctgtgacata agtaaaaaga
     6001 tagtttcaaa tttcgaacaa taaatttgaa actatcttct ttataattat aaagtatcga
     6061 ttttacagcg ttctataatg attcatagaa tctaaaacga atgattttaa ttatcaacgt
     6121 tttttaattc gtttttagct taaaaataac ttttgtcaca gtctcactcc taaaattact
     6181 ttatttacgt atgaagtggg caggaggtcg aatccagaac tgggctatgg tacttcaacg
     6241 aggacttctc ctctagaatt gaaaagcatg cgatttacct tccgtaacga cggtagattt
     6301 attcaactat gtgtccaatc aaaatttgtc tgatttcaaa aatagtcaag agaattttgg
     6361 ttgttaaaaa ctcttatcta tcaacttcca cagtttagtt gacaaaccct gatactaagt
     6421 tgggctatga tacacttttc ttgactatca gttacgttac cggaaggaat gaactctatt
     6481 gagaaaaaca tatgatcgta aatttaaact aaagatttca caggatatcc ttgagaaaaa
     6541 agtaactacc aagaaaattg ctgaagaata caatatctct cgtccaacaa tttcccgatg
     6601 ggtttcagaa tatcgtcgat acgggaaaaa tgcttttgct ggacaaggaa aaagattacc
     6661 tgataaagca gatttctaca ttcttgaaca ggaaaataaa cgactaaaag aggaagacga
     6721 gtgttctacg aacacaaaga tcgatacgga tctccaggga tcactcaaaa actttacgat
     6781 gaaggaatcg aaatcaataa acgtgttgta gctgttctta tgcgtgaaat gaatttatgc
     6841 acaagaggat ttcatcgacg caaatcttct catggtagag aaaaaacaat caaagaaatg
     6901 gtaaaaaaat gttgaatcga taatttgaac agaaccaaat tgatgctgtt tgggtgatgg
     6961 atattactta cattccatgt aatgacggtc gcctctattt gtccacctat attgacttag
     7021 caactcgtat tctacgttac tatatggtag attcacacat gaaaaaagag attgtcgtcc
     7081 gtccattaca aatttattaa ggagaattgc ctacggtaat tcattccgat agaggtagcc
     7141 agcatcggtc ttttatttat caagagctgt tgaacgacca ccacatcaca cattcagtga
     7201 gccaaactgg gactcctgtt gacaatgcag taattgaagc gtttcatcga tcaatcaaat
     7261 gagaattaat cgactccaac aaatataaaa gtaaaataga gatgaaggtg ttaatccaag
     7321 attatttaga agactactac ccaaacaaaa gaatccatac aaaatttatg atgactcctt
     7381 gacaatttga agcgaagaaa ataagggatc tataatatct agtgttggtg acgccttctg
     7441 ttgccaatac tttttctttt ttctaataaa cgcaaacaga caccttaaaa tcctttagaa
     7501 taaagtcgac gaaaaccatt caaaggagtg tttcaagatg tcctattcag agtttaccaa
     7561 agagttacta gatattctag acctaaatct tatctttcat gaagatgcct ttcgcaaaga
     7621 gcgaatcaat gacgaaacat gttttgtttt tgatggcaca ttgacctatc aaccggagga
     7681 atgctttcat cgccactatc aaaatgaaca aacgatcatt aaatagggct ggaaaaaagt
     7741 atccatctta ttgaatgatg tcagtaacta caagaccatt ctgcggatta acaaacagcg
     7801 cttcaaatgt aaacactgtg gaaagacttt tttagcagaa gattcagtta gtgatcgtcg
     7861 ctgctccatt gctcgcagag tcaaacaagc cattcttgag ctattaagcg aacctctttc
     7921 tatgtctttg atcgcacgta tgaagcacat ttctccgacc actgtcattc gaatacttcg
     7981 cagccttcgg cctaaaacca tttctttgag ccagctgtta ccagaagtgg tgtgtttcga
     8041 tgaattcaaa tcagtgaaaa atgtctcggg agccatgagc tttgtcatga tggacggcaa
     8101 gacccatcaa ctgattgata ttgtggaaaa tcggcaactc aatcctttac gcgactattt
     8161 cttgcgctac cctataaaag tccgtgaaca agtgcgtcta gtggtttcag atttctatac
     8221 accctatcgc acattggtga aagagtgttt tccgaatgcc cgaatcgtcg ccgatcgctt
     8281 tcatattagc caacacattg gtcgggcttt taccaaccac cgaattcaag taatgaagac
     8341 ctttaaaaaa ggggatcgtc ggtcgaagca cttaaagaaa tactggaaac tacttcaaaa
     8401 gaatgcgtgg gaattgaaag gtcagcatcg ctactggcgt ccgtcatttc gagatcatct
     8461 gacagaagca gagatagtcg atcggctatt atcttatgat gattccttaa agcgaggcta
     8521 cgaagtctac caggattttc tttccgttat cagaagacaa gatgttcctg aattcgtcgc
     8581 gctcctaaaa gaagactaca aggagttgcc agagcactac caaccagtgt tcacgacctt
     8641 caagaaatac caaacagaaa tcaaacgagc gttgcgcgtt ccctattcca acggccctat
     8701 agaatgtttg aataaccata tcaaagtact aaaacgaatt gcctatggct atagaaactt
     8761 tcaaaactac cgagaacgaa tctttttata tcgaggaaaa tattttaaga aaactaagaa
     8821 tactacccaa ctgactaaag ccagaacaac aacacggcta gacaagatag ctgtctagcc
     8881 gtgtgagtat ctcgattatt ctattgaatt tcttcaccaa cactcattga cgaagagcca
     8941 aaataagtaa tctaaccgac tgttaactaa accattgcag gtcccgttaa agatacttgt
     9001 gcctgttgtc accgcttctt tttcttgtcc acaagcgctt aacacactta ataaagcccc
     9061 tgctattatt aataataata tctttttctt attaaaaacc tcctcatcta tttccagatt
     9121 agtaaatgta gtaatctgtg ctttcttttt tctcaatact aataactaac ttatggggta
     9181 aacaaatact cgtttgaccg ggttttgaga tccatccagt tctaaccgcg atttgatcag
     9241 gactattatc ttctttaact cgaattcttc catctttaat ctcaacaata ttatattgtc
     9301 ccttcgcagg atgataattc acgagtttat gattgatctt atccaaatcg aagcgatcca
     9361 tttccttgcc atcaattcga acgatggcat atttgatagc atcttcagtt gtttcattct
     9421 ccttttctat agagaataca aataagggaa taaaagaggt aataatcaaa atgccaataa
     9481 ttatgacatc gcctatcttg acaccagctt ttcttaaaaa tttcattaac gatatctggc
     9541 taaacatatt agactttttc catggaaatg gtgaaatttt tcggaaatta tctgcattaa
     9601 gagaatcagt taaacaaccc tcaagttgtt ccttaataca ttgttgatcc atcttcatac
     9661 caataaaaac tagtttatta atgcgttcac caaacaacgg atgccaggct tccttcaatt
     9721 cgggattttt ttgtataatc atttgacact caattttagg taaactagct acccaataat
     9781 ttaatgattc aatactttta tagctacccg atgtttcaaa gatcgtcgaa aaatcactat
     9841 gttgggcaaa ccaaagaaac ccttttgctc ttgtaatatt gccaggaaaa tttttatccg
     9901 taagatgggc aaatttttgt gcgtcaagga gtaaccgatt tcgatagata aaacttgaga
     9961 taccatattc ttctgtttca ggaatatgat tttgatagcc aagctctaac tctttgaacc
    10021 agcccactga ataggaagtc tcatctatat taaaaagatt tgtatttaga attttcgata
    10081 agtctacttc acctttaatt gtcctaatta ttttggcatt ggactgtaac ttagcaatta
    10141 gaccgttaat tttgtaaatc gtcttggttg acactaagtc actattattt aaaagtaata
    10201 tgttacaaca ctcgaattga tcaattaaca agccacgaat atcctgttct tcttcaacta
    10261 cattaccttc agcttttctt tcctgaatct tttcacccgt ttcgaaatta tcccaaaaac
    10321 gttttacatc cactactata ataatggcac caatctctaa tcgttgggtc aaatcaatgt
    10381 ctaaagggtt tttagctaat ataattgctt gaataattgg aattggtttg ctgattcctg
    10441 aagcttcaat aacaatttga ttcaagtcag aaaattgcac taattgatct agttcaacaa
    10501 tcaaatcttc gcgtaatgta caacaaatgc atccattcgg catcgaaaca agtttttctc
    10561 cagttctttt aaaacctttc ttgtcgacta ataccccatc aacatttact tcccctatgt
    10621 catttacaat gacagcaatt tcctttccgt gatcaccgta cagaatatga tttagaagta
    10681 tcgtttttcc tgaaccaaga tagccagtta agattgtaat aggtattttt ttcataggga
    10741 acctctttct ataccttgaa tttacacttt aagtgcaaca cataaaaatg agtcataatc
    10801 gatatccaac tagtataagt ttgtcgagaa cactcctaga aggaaaataa ttatgagcca
    10861 gtatcgtcat cttactatac tcgaacgaga aagaatcttt ctgcttcacg aagaaggatt
    10921 ttctattagt ataattggca acgacattca gcatagcccg tttactattt tacatgaact
    10981 gagaagaaac aagaaaaaaa ctattcacct tccaaagcgg aaaaaaatta tgcttatcga
    11041 agaaaaaaat gcggacgtta tcacattcta aatgatccgt gagtttggtc aattgttcgt
    11101 catttatttg tcgattttca gtggtcgcca gaggaaatct cgaatcgttt gaagcatgaa
    11161 catatggact tttcaattag ttttatcacg atctaacgtg caatttgcaa tgatcttttc
    11221 gatacagaac ccctctcaca cggcaataaa ggcctgatcc gttcattgca ccatcgagga
    11281 aaaacaagac atacaaaaaa tcatgtcgag tctcgtggaa agatttgcct tactcattcg
    11341 atccatggcc gtccaaaatc cgcagatgat agaagtgatt ttggtcattg gaaagccgat
    11401 attgtagctg gcaaaactgg tggtacttgt ttagtgactt tgacagacag aaaatcatgc
    11461 ttccttttag caggaaagaa ggtccccaga aagaaagccg cttatgtgag cgagaaaatg
    11521 attgaacttt taagcagtat tccaaatgag gcggtcaaaa cgatcactcc agatagagga
    11581 aaagaattct ccaatcattt cgcagttaca gaagcattga ataatatgcc cttttatttt
    11641 ccagatcctc atgcccttgg caacaatgaa caaattaaaa tacgaataga ctcattcgag
    11701 aatacttgcc aaaatcgaaa gagatagcta cggtagataa ctcaacgata aatcagatga
    11761 ttgaaaaact gaataacaga cctagaaagt gtttagattg gagaacacct tatgaagtct
    11821 tctttgataa agtgttgcgc ttgatttgac aattcaagac ataataaaaa gcagatcaaa
    11881 tccaaataag ggaaaaatga tctactctgg tattatcaat taattggcca agctattatg
    11941 ccgttttgct aaacgtctac ttcttccagt attgaccttg ataaaacaac aatcaggatc
    12001 ccgttttaat actctatgaa ctgtgtcaat actaacatgt aaagttgcag caatatcagc
    12061 taatgtactc ccatttaatc tcatttgctt tgcaaatcga taacgccgat aagcatcaat
    12121 attcttggaa tccatagaca ataatacttt tcttaccatg tatttcctcc aaaaattgaa
    12181 ttttaatgag ccatcatttc ttgagcaatt tcatgtttag acaatgaagc tggatagaaa
    12241 gtaggccaat tatgcaattc attatagagt ttttcttgac tttctccacc aaagaaaata
    12301 tggaaatgct ctgccttact tggtgcaatt ccatgatcac taaattgaat atatttaaaa
    12361 cgaccagcac ctgcatcatc agtttcaaaa ttaaaacgaa caccacggtt tcctttttca
    12421 taattcaaaa ttttgtatcc aacatatttg tatgtgtatt gatgatgttc accgttgact
    12481 acaaaatcaa tggtgttgtc tttaatgttg atagtatcaa tatctgtctt atagccagta
    12541 gtataataat ctttgtactc ggcagctgtc atgtctttat tgatttttgc tttgtaatcg
    12601 aaaacttcat ccaaaattcc atcttttaac aacggataaa cagattgcca ttcgcctgta
    12661 taatcactca attcgcgatc cttcacatcg gcatctttaa agtacccatt agcaactgtc
    12721 ttttcatcct tcgcttcttt ttctggaact acctcttcac cagcaaccat agttgttttt
    12781 tctaacgctt ttagattgtc ttccattact gaaacataat cttcaccatt atccatttgt
    12841 tcttttgtaa gactttcaag aggattcagt acttccaatt ttatcccagc ttcgttggcc
    12901 aaagtttttg caattttatc attagcattc ttttcaaagt aaatataatt gatcttattt
    12961 tttttaacat actcttttaa ttcagctaat cgaccagaag atggctcttc ttcaggactt
    13021 agtccagcaa taggaacttg tttcaatcca taatccaaag ctaaatatcc aaaggctgcg
    13081 tgttgcgtca caaaactttt ttgtttcgct tctttaagac tagtggtata gtcagcatcc
    13141 aaccgtttca gtttagtcaa atacttttca gcatttgtct caaatacttt tgcttttttc
    13201 ggatacaatt taactaactg atccttgata tttgaaactt ccttaattgc cattttgggt
    13261 gaaacccacg tatgaggatc tagttcatga tggtgatctt cttctccgtg atcatgatct
    13321 tcttcttcac tacctggcaa taaaatcatg tcttttgttc cttctactac attaggccca
    13381 gctttcttcc aactttcttt agcttttggt acccatgatt ccatgttttc gttatgatat
    13441 acaaaaacat cagcatcatg agcttttgcc atatccttag ctgagggctc atagtcatga
    13501 ggttctgatc ccgctggaac cattaaatcc acgttcgctt catcgccgac gatgtttttg
    13561 gtgaaatcat acattggata gaatgttgtt acaatttcta attttccatc tttatcattc
    13621 gatacttttg catcattagt gctggagcaa gctcccaata atcctagagc tgctatccca
    13681 ataagtccta cactgatttt cttcattctt tttccttcct taattatgct aatttcttca
    13741 ttttatttcg tttatgttct ttgataattt ttaatgccct ttttctagtt ttaatattcg
    13801 ggcttttaag tcgtcgatat gcactagata tatccgtttt ctccattaga aattaccccc
    13861 aatcactact tatcattatt tgctttccgc cagtaattta tcaaaactct gtttgatcct
    13921 ttcttcatcc aacatttttc cgattagaat aatagtggtt tggtcttttt gtcgagtggt
    13981 gtattgaaaa ttaacctgtt cgtttacctc ttgcatggca actataaaat cctgctcttg
    14041 taaagcaatc aatcctttaa aacgatacag gctcccttgg ttggttaaaa tcagccagtc
    14101 aatccattgg agtaaaaaat ctttttttat gtcttgatct gaagttaaga gaattgattt
    14161 aaactcatgt acttgatggt gttgatgata gtatttgcca ttatagtgat tttctgatga
    14221 atcactttca aaaactaagg gatgattaaa ttttttcaaa ttataaaaat cctttttttg
    14281 aatcgtttca ctatgtgtga acattcgaat atcggataaa gggttaatac ttttgatttc
    14341 tctctgtaat ttttttagtg cagataaatt caagttttgt tttctagaca caaaaatgcg
    14401 atctgccatg acaagttgct taagggcttg tggttctctt tcaataagtt caaaactgtc
    14461 actatcaata acagtcaata aactatcgat atatactctt cctcttagtt gaggcgctgt
    14521 taaaagtgtt tgaatgattg gttggggatc tgctatacct gtagtttcaa tgatgatttg
    14581 tgaaattggt tgttgatgtt cttctattgt ttccagtaaa gaaatcaata ttgctaataa
    14641 atcactgcga agactgcaac acatacatcc attatttagt tgtaacaccc gttcctcgct
    14701 atgaactaat aatttgtgat caatcccaac ttcaccaaac tcattttcaa ttataataat
    14761 ttcttccctg gggtagggtg agacttgcaa ggcttgattg attagcgttg tttttccagc
    14821 ccctaaaaac ccagaaacga ttgtaactgg tatgcccatt ttgtcacctt tttaccactt
    14881 agctatttca cttctttaaa aattgcccgt ctgcgcaatt ttggcgaata cttttttaat
    14941 tctaaccgtt cagggttatt ccgtttattt ttgctggtga gatacagacg ttctccagtt
    15001 tcgacacatt ccaaaataat attttgacgc ataaatcttc ctccttcaat acttatcgat
    15061 cttcaagata tgcttgaatt tgttgtgcat cttcaaaagt taactcgcca gattccaatt
    15121 gtgaaactaa attttctttc atatcaacag gtatctccca ataaccatcg atacattgaa
    15181 ataactcctc gtcatactct tcaaaaattg gatagattct taaaaaatca tcaaatgata
    15241 agccttggtc ctcatagtaa tctttgacta atccattttc aattgcctgt tgggtcggta
    15301 aacccgtttc agtaataatt cctctctcta ccatcgaacg ataaaaagtg catttatcta
    15361 gcgattgctg ggtcgtttca agataatact ttaatccttc ttcaactaaa ggtgggtaaa
    15421 taatttccat tttgattccc tcctaaaagt tatatattaa actattttga agctccttta
    15481 attactttct ttccattata gtaccctttt aaagatacat gatggctacg tctataatca
    15541 ccattcgctt cgtcaaatga aatttctggt tttactacag tttgatgagt tcttcttaac
    15601 cgtttcttcg ccttagatgt ttttcttgct ggtactgcca tgatatttcc tccttttacc
    15661 aacttgcttt ttttactcca ggaatcaacc cttgatgggc aagttctcta aacttaatac
    15721 gggacatacc gaactttcgc atataccctc ttggacgacc atccgtctga tcacgaagcc
    15781 tcagacgatt cggatttgaa tctcttggca atttagcgag agcggtgcga tctcctgcgg
    15841 cttttaattc ctgacgttta tctgcatact tttcaatcat cgccatttgt ttctttgctt
    15901 tagcaatttt cgactttttt gccatatacc tttatactcc ttttattttg atttagacac
    15961 ctcaaatcgt aatcgttacg ttttgacact gatactttac caacaagagt tgctcttgtc
    16021 aacaataaat aacatgaaat aaaactcata tgaatagata actatttgaa aacgaattta
    16081 tcggtacata gagataatca aatcatttaa aagaatatgc agtttaggct ctgaaaaata
    16141 agaattcact tttattagtc caatcaaaca caaataccgt tttaagtagc ttttcctcta
    16201 cttaaaacgg caatatgaaa gaaactataa ctttttattc aatcttttat gtttaactgg
    16261 tttatcgcca attttttaaa actttgatta ttccttatat tataagaata gacattaagt
    16321 gaactaattc aatcatactg attctttcgt gtattcaaaa ttagatgctg tttaataaaa
    16381 ttattctttt tgaaaaagaa ttataactat atcccaaaaa ttgtaggtta atttaaagcc
    16441 tatttcatca tcgtgattga gcttcttttt catagacgaa tttctcagat agtttagttt
    16501 tctttatgag atttttgtat atttctgacc ttcgatacaa ctcattatga gtaccttgat
    16561 caactagttt tccttgatcc atcactacaa ttttatttac cttttcaata gacttcaagc
    16621 gatgcgatat aattagtact gtcttatctt gtattaaacg atttaaactt tcctgaatac
    16681 gtttttcatt ttccgcatct aaactggcag taatttcatc taaaattaaa attggcgcat
    16741 ttttcaaaaa agcccgtgct atggataggc gttgtcgctc tcctccagaa agtgaacttc
    16801 cgttttctcc gaccaatgta tgataaccgt caggtagttt ttcaataaag tcttcgcagt
    16861 tagctaaacg agctgctttt ttcacttcct catctgacgc ttgactattt ccaatacgta
    16921 tattttccaa aatacttgta ttaaacaaag ttacctcttg aaaaacaata gcgattttgc
    16981 taaacaaaga agctggagat acacgtttaa tatcataccc atcaattaaa atacagcctt
    17041 catcataatc atacagtcta gacactaatt tcaagatact agttttcccg gaaccactag
    17101 cacctactaa cgcagtcact tctccttgtt tagccgtaaa agagatatga tctaaaattg
    17161 gggtattgtt atcatatgag aaagagacat ctcgcaactc aatgtcaaaa gatttcagag
    17221 gactatctga tccctcttgg atactggttt ccttcatagc tctaattcgc tgtattttag
    17281 gagctaaata aaatatttca agcactgctt ctttcataga atcgaaggaa tcctttattt
    17341 ttattgcggc tagtaagtaa ccaacgacgt agagtatagt cacttcaccc gttaacagta
    17401 agtgaacacc tactagaatg actactgcta aactaacata tgagaaaata gaggataagg
    17461 ccatgactga aaaagtactt aattctacct ttaaatgaat cctttcactc tcttccattt
    17521 ttttgaaaag tctgtcttga acttttttag atagattaaa gctattaatc tcttgctgca
    17581 attctatagt ttcttgaaat tcttccgagt tttctctcaa agtatcgtaa tatttagtat
    17641 tggctttcgt ttgggatttc tttgataaca agattaagac aaaactaaat aacgttggca
    17701 aaataacagc taatcccatt ttgacattac caaccaaaag catcactgaa ataaaaggga
    17761 aaaacagagc cataccgccg gctttaggta ttgcatgact catcgcatgc tcaatacctt
    17821 caacgtcaga catgatagtt tgagataaat ctgataaatt atgttttgaa aaataggata
    17881 atggtaaatt tgacaaatcg tctgcaattt gcactcttaa atgcgcactt tctttataag
    17941 tactattata taagttttca tactccctat ctaacaacca atacatgaaa agcaaagtaa
    18001 caaacgatac ggcaaaataa agccaacggg gctttgtatt ttctaaaact aattcgtcta
    18061 tcagcatcat tataatgaat gctggtacca tattaatgca gtatacaaaa aaactagaaa
    18121 tagaagcttt agttaaagct tctgcgccct gatcacttaa agcaaatttg tttttataaa
    18181 aacttttcat tgtcaagcct ccaatcattt gcattctcat aattagtgac caattgttta
    18241 tacacttgat gtttagccat taattcatta tgatttccac gttctactat tttcccttct
    18301 gacaagacaa gaatttcatc tacagattta atgctggata atcgatgagc tatcataata
    18361 actgtttttt ctttcatcag atgttgaaaa gccttttgta gttcatactc attatctgga
    18421 tcaatagatg cactggcttc atccataata acaatctttg catcttttaa aattgctctg
    18481 gcaatagcta tacgttgttt ttctcctcct gacagataaa ctcctttact accaattaag
    18541 gtatgctctc tttcgggaaa tttttctaaa atcgattcgc aaccggctaa tcttagcgcg
    18601 tcaaatactt tacttgctgg cgcttgagga tttgctatag aaacgttatc gtaaatactc
    18661 tgattgaata gtttcgtatc ttgaaagaca aaagcaattg tgttaataat tgtgtctttt
    18721 gaatagtgat ttaaaggctt accaccaatt ttaatctgtc ccttatccac attgtagaaa
    18781 cctgaaatta gtttagctat cgtactcttt ccgcttcctg attttcctac taatgcataa
    18841 attctttttt gttctaaaac taagttgaaa ttttctaaaa cacactcttc tttgtatgaa
    18901 aagctgacat tttcaaatgc aatgtcacaa tttttaatct gtgtctcgtt cccatatttt
    18961 agttggtctt gcttcatttc taaataaagg gagtctagtg tttcgactgc atatcttgct
    19021 tcaaacaagt gcatacttac atacattatt ctcatgaaag aaacaaaaat aattccactt
    19081 aaaaaaaaca acatcaacaa gtcaacagct aatatcttgg gagtggtaag agaagttata
    19141 aaaaaggtta taggaactat caaaatgcaa actatgccaa aaaatagcca ttgaaaaaga
    19201 acaaaaggtg ttttcccact caaagaatac ttatatgcaa acttagcata atcgttaatt
    19261 gctttattca aggctttaaa tgatgttact ttagcaccaa atatctttat aacttgaatt
    19321 ccgcggatat attctaccgt ttcagagctt aacacatcta acgattcttg atatttttga
    19381 ataaaatttg tattctctgt cattttcttt aacaagaata caccaattac taacatggcg
    19441 attagaacca atccaatttt aaagttaatg aaaaagccta aggcaactga taaaacaggt
    19501 gttactatgg cttgagcact atctggaatc aagtgagcaa ttgccatatg tgttttagcc
    19561 gcgttgtcat caattgtctt tcgaatatat cccgaagaat ttaaatcaaa aaaacgaaaa
    19621 cttgcttctg ttaaaccgct aattcccttt tttctcaaat tagtctctaa gcgaaaccca
    19681 aggatatgag aaaataagcc agaaaaaata taaaataaag ctcctaaagt taaccaagca
    19741 acagtttgaa ccgcataact cttagctaaa tattcatctc ctacaataat tagagactga
    19801 agaaatttgt aaatactgta atatccatag actgttaata cgacagaaaa atcagaaaat
    19861 aaagtggcta accatccgta gtatttcatt ttagggacat aactaaataa ttttttgtat
    19921 actttcattt tttcctcccc cgcattcaat ttcttctctt attcgtttac aactgttaat
    19981 gctttccgta atagcgtaaa ttagagatgt acaaacagat aaaaggtaaa ctacgttcta
    20041 ttttttgtat ttttttaaga cttttcttcc aatcaataca ccaatcatag ataaacttgc
    20101 tacaactaac actgaaatga ttccccatat acctaccgca tagtggatca ttgcatccat
    20161 tgttgcagca gattgtcctt tatctatcca atcttgacga aaacgatctg taaagaacca
    20221 tataggaatc cactgtccgg cagcactgcc taattgcatt agagcccaag acgcaacttg
    20281 aggaattgct cgatcatatc caaatacaga tagaataata tcagctaaga tcgccatact
    20341 aatcgaactg ataaaccaag gtaagtacgc cccgcccatt aacgtaaaaa ataacaataa
    20401 aacaattgtg taaatagtaa aaattccttt tctagggtag ttatagctaa tataaacaaa
    20461 tatgattcca gataataatc caaaaatccc gggggatatg ctgtgaccaa acgccccacc
    20521 aatactacta accattattg aaaaaaagta aattactagg gaaataactg tagctaaacc
    20581 aataaaaata taatcttttg ttttcatata tattctcctc aattctattt cgttatgtca
    20641 ttaaaaatct gttctatcaa agttgaatct tctactctaa gttttatatc tttttttatt
    20701 ccaccatttt ttaaataaat aattctattg catgttttat aaagaaattc cggatcatga
    20761 gtagctataa ctactgcacc cttttctttt aagtctttaa taaggtcagc aatcctttcc
    20821 atattaatat aatccaaccc acttgtaggt tcatcaaata gaaataaatt agtttttgac
    20881 aatgaagcta tagaaaccaa taatctttgt ttttctccac cggataaatc aaacggtaat
    20941 tgatctttca ttttataaag ttccattttt tttaaaattt tttcttgctg atctttacta
    21001 actatttcat tccccagggc taactcgctc ctcactgatt ctgtgaaaaa ttggtaatcc
    21061 atttcttgca ttactaaaaa cggcgatgac aaattttttt tattttcgat tatctttcct
    21121 ttggtagggc gaataatctt catgagtatt cttagtaagg ttgttttccc cacaccgttt
    21181 ttccctacca aaccaataac atctccaact ttgacatcaa aatttatgtc ttttagaata
    21241 ttttcataag taatttcttc aacttttaat acatctgcac ttaccttttc gatataggga
    21301 acttcaatcg aactattaaa aatgtcaaat ttccttaatg cgttattgtt ttcagttttt
    21361 aacaactgaa tagttgtagt ttttacagtt ctatttttaa caaatagaac ttgatcaatt
    21421 aattctttca aatagtaaaa acgatgttca gctataacaa tagtaaatcc tttatttttt
    21481 aaatcacaaa gtaagtcagc aagtttctta gtcgctttga agtccaaatt tgaagacggt
    21541 tcatccaata taattaattt agagtttagc gataaactac atccaataga aattttctgc
    21601 cgttcaccac ttgatagcga aaaaatgttt ttatctaata tatttgaaag atctaataat
    21661 tcagctaatt cattgattct tttatccata tgctcttttg taaatccaaa gttttccatc
    21721 gaaaatacta actcactcgt tgtatttgtt gtaaagaatt gtcctctagg atcttgactt
    21781 acgtagccaa tattttttga tatactttct tgtgttaagg attgtagcga gttattttca
    21841 aataaaattt ccccaaccaa ttttccgtca taaagtcttg gaataagtcc attcattaac
    21901 tttaatagtg tggatttccc actcccagaa gaaccagtaa tcaatgtaag actgcctttt
    21961 tttattgaaa aattaaggtc aacaagcgct tgttccttaa catccttata tgaaaaagaa
    22021 acattgttaa attcaaacaa ttctttcacc tcaaatcaaa atacttaaga aaaaaatagt
    22081 aacggaaaac aggatgatat agtctaataa gctcatgttt gttttatagt aagaacttct
    22141 tttcacagga gattctatcc cctttgttat tgcattagcg gtcatttctt cagcaatcat
    22201 agttgcacgt ataagaacgg gaactaacag aaattccaaa tattgcagag gctgaaaaaa
    22261 agacaagcga atgtttctca tttttaaaga ttctttaatc attcttattt cagaacgata
    22321 agtcggaaag aatctgatca ctactgtaat acttaacatt atttttttcg gtaaatgtat
    22381 tttttctaaa gaggataata attcattgct agtatagaca ctaaccaaca accatgagat
    22441 cattacgacc ggcaacattc gaaatacaat atataaggat gtcgcaaaaa atatagtaaa
    22501 aaactctatc ttgatagcat caataatttt cattactaaa aacagaactg aataaatcaa
    22561 gatgaaataa atacatgtct ttattttacg aaacatcaat actaaaactg tagcaataat
    22621 gaaacacccc acttgaaata tatttccctt tcctaaaaaa ataatgaccg gaaaaaaaat
    22681 atttaaagta atcaaggtta acggattgat ttttgacact ctttcacctc caaaaaataa
    22741 gatcgcactg ttatcttaag ctgataaaaa tgcaccgtta ttcagataac agtgcgatct
    22801 tatcaaaaag cataactgag aacaattctc aatgcaagct ttttttaatt aactcagtaa
    22861 ttcaatccac ccaggaacag aaaattgata caatcttctg gttaatagca tagtcttttc
    22921 ttttgaatag ctatgcttca atatatcata gaatgtagcg tagaatgagt aaatgtagaa
    22981 gtggatttct tcttcattaa agactaaatt ttgattgatc attccgatag tctttaactt
    23041 atctagacaa cagactgtct ttttcgtcac aaatgatgta attttttcaa caatatcttg
    23101 atatttggtt ccagctgatt ggaataaaat caaatcgaat atacgtttat tctcaaaaat
    23161 ataattaata aatggatcta attcattgaa gttctctctc caacttttct ctatatctat
    23221 attttctaag tttaagaggt atttggtaaa ctcttcatta tacatattaa taagcgcatt
    23281 aatatgcggc tgaataattt cttcaaataa cgcttcctta gaagtaaaat gtttataaaa
    23341 agcacccgta gttacgcctg cggtcaggca cagttgcctt atcttagttt gctgaaatcc
    23401 ttctttttca aaatggctta gtccactttc tattaacttt tggtgagtta taatataatc
    23461 tctggtttct atgggtactt cctcctaata agatgaatta actttattat cttacacagg
    23521 acttgaagtt tcaatcgtta acgtttatta ctgaactcat tccttagagc taaactaatg
    23581 agaaagagca gaataactga tacaaaaagc aatcctacaa gaattaatag actcatctaa
    23641 atcattcacc ttttctaaaa taatccgaga aagatttaaa aaaattatat ccagctatta
    23701 ggataagtcc tatcataatc actccaatag ccattttctt atcctcccta aaaataaagt
    23761 cttttactta aaaccttttt tgtaatcgtc aataaatttt ttccctttat cagttaattg
    23821 aaatcctata tctaaatagt cctcatatct aagtttagcc agcatctcac ttacagatgc
    23881 tggactaaca cttagaactt ttgctaaatc attatttttt aatttctttt ttctttttga
    23941 taattcctga attgctagta aataaattag tatagtagtc gttttaattt gtaccatacc
    24001 taccctccaa attatttcga aaggccttca gcaattttat ccaggttcca tttcatcatc
    24061 gcatagtaac tatcaccatc ttgtcctttt tctgcaattg aatcagtaaa aatcgttgaa
    24121 tagataggaa tattggtatc ttttgatact gttttcattg gtctatcatc cacactgctt
    24181 tctacgaata aggagggaac ttttgttgtg cgtaattttt caactaagtg ttttatttga
    24241 tctggtgttc cttcttcttc agtgttgatt tcccaaatgt aagcagaagg cacattatac
    24301 gctttcgaga aatatttaaa gcatccttca cttgtaacaa tcattttttt atcattcgga
    24361 attgaagcaa atttagattt agcttctttg tctagagaat ccaatttttc aatatactta
    24421 tctagatttt ctttatagaa ttttttatta tcaggatctt tttccgctaa ctgtttttca
    24481 atatttttag cgtaaataat accgttttct aaatttaacc aagcatgagg atcttccttc
    24541 cctttctcac tctgaccctc taagtaaata acatctatgc catcacttgc tgcaaaatag
    24601 tctttgtttt cctctttgtt cgcattttta actaattttg taaaccaagc atttcctcca
    24661 gtttccaagt taacaccgtt ataaaaaatc aaatctgctt ttgaagtttt ttgaacatct
    24721 tcaggcaaag gttcatattc gtggggatct ttcccaatag gtacgatact gtgtaaatca
    24781 attttatctt ttgctatatt ttcggtaata tctgctaaaa tcgaattagt aactactact
    24841 tttaattttt cgttcgaagc cactttatct ttgtctttac tatttattga acatgccccg
    24901 aatataaaaa gagcaatcaa aatccccaga cttcccagta ctgctttcca ttttctcatc
    24961 ataacgatct ctccttcttt cttaaaaatt tttgttttgg tgagattaga aaactaatta
    25021 caaataagaa tgccgctgtt aaaacaatac ttgatcctgc tgctatgtta aaactataac
    25081 caataaacaa tccaagcaat gatgaacttg ctccgactgt tgcagaaata aatatcatag
    25141 ttttcaagct atttgcatat aaatatgctg tagctgctgg tgtaattaac attgcaacaa
    25201 ttaatatagt tcccacactt tgcatagctg ttactgctac taaagttaat agaaccatca
    25261 atagataatg ataaaaactg acattcatcc ctattgcttt tgccattaat ggatcaaaag
    25321 aagtgattaa taattcttta aaaaatagaa ctactataac caacactaaa accgaaacgc
    25381 caattgtaat ccacttatca atatcttgta cagctaaaat atttccaaat aaaatatgaa
    25441 ataaatccgt tgagctattt gcaactccta taaggataac tcctagtgct aaaaaagaac
    25501 tgaaagtaat accaattgct gtatctcctt ttattacact attgcttttt ataaaagtaa
    25561 taatgataga agctaataga ccaaatacaa tcgcaccaat aaaaaaatta atacctaaaa
    25621 tataagaaat tgctactcct ggcaaaacag catgagaaat agcatcaccc ataagagaca
    25681 ttcctcttaa aataataaaa caacctactg ttccagaaac aatccctata actacagatg
    25741 taattagagc attctgtaaa aagtgaaagt catacagacc attaataaaa ttttgaagca
    25801 tattattccc cctctccaat aaatatagta tctccatagg ctttttttaa attttcttca
    25861 ttaaatacag attctacact tccgtgagca attagatttc gattcaaaag aataatatta
    25921 tcaaaatact tctttacctt gcttaaatca tgatgcacaa ttagcactgt ttttccctga
    25981 tgtttcaatt tttttaacgt atccataatt attcgttcac taactaagtc tatccctaca
    26041 aatggttcat ctaaaaatat gaaatccgca ttttgagcaa gacatcttgc taaaagtaca
    26101 cgttgaaatt gtcctccaga taattctcct atttgatgat tagaatattt tcccatatcg
    26161 accttttcca aagcctttga aactctttgc cattctgcat ttttaattct ttgaaaaact
    26221 ttcattccgg catatgttcc catagataca cattctttta cttttattgg aaaagtaaaa
    26281 tcaatatcag ctttttgctc tacatatgca atcttcacca gttttttatt gatatcttca
    26341 ttattaatgg agacctctcc ctgatgaggg ataatattta acattgcttt aagcaatgtg
    26401 gattttccag caccatttgg accaataata cctgttaaag caccttcttg tatttttaaa
    26461 gaaatctcgt tcaatgctaa aaaatcgtta taacaaacat taagcttttt cacttctaac
    26521 ataactttct ccttctaaat gataatgatt atcacgatca tatggtatac aaaaattata
    26581 ttttagtcaa ccctaaattt tatagtttag atttttttct gttgctgaag attagaatga
    26641 caaaactatt tgaaactacg cgtatagtaa gtagctttca aaatatataa aaaaggagcg
    26701 ttctcaaatg agaacatgct cctaaaacta ctttattggc gtatggaaaa attatacttg
    26761 aagtggatag cgggttgaat aagttgataa gcatcaaaac atttataaaa attattcaag
    26821 actatgtctg ttccatatac aaatatgaaa atcagtaaac tccatttaac ttttttcgta
    26881 gtgtgtcttt ttatacatgt ttatcgttat taatagtgaa taggaaaaaa actatttttg
    26941 atcattgaca attaaataca atttttgaat aacgatccct gctattcgag ctagaaactc
    27001 aagtacgcca tgacctgatt agcgacaaat acttagagat ttctttttgt tctgggaaaa
    27061 caaaatgcca tgacaatagc agcaaataat gatacttccg taaggctcgc cgtaaactgg
    27121 ggagaggtga aattcctatg tgcttaccca aagcaattca aaaatttcat aactactatt
    27181 ttaggagatg attttataga atccagagtc tacctgaata aaaaacaaac ctgtgcattt
    27241 ctaggaatcg ataataatac tctagataag tggattcgta tatataattt cccagtaata
    27301 agagttggtg gtgtagttcg ctttgacgta gaagatatta aagactttat gaatacttga
    27361 aattttcttc tcgccgcata tactaaaatt agtgaaatat actgccttac tttttttaag
    27421 gagtgaggat tttgcctaca aagctttcaa atgggaaata taaaactaat ctgagatatc
    27481 caaaaaggtt taaagaaata acaggaattg catcagaaaa gtatcaaaaa acatttccaa
    27541 ataggcaatt ggcgattaaa gccgaaaatg atatgaagaa gaaaatagaa aaagttttga
    27601 gagaggagaa tgcaaactca ttagaattaa aaggaaaaat aacgtttaaa aaattttacg
    27661 aatctaaatg gcttcctaga tatgaattag gtcaaacaat tagatcaaac aggcctccta
    27721 gtgatataac cattagtaat acaaaagata tatttcggtt gcatatttta cctatgtttg
    27781 gtgaatacgc aatgaattat ctaaatatca atactgagat aatatcagat gaattaacca
    27841 aaaaatcgaa agaatatgca aatataaaaa tcataaaagg atatgttcgt tccatgttcg
    27901 atattgcaga aatactaaat tatatcgaat ttaatcgaac tactaaaatt attcaaagta
    27961 tcactgcacc taaaaaaaat gctttagaag aaaaaagaat acaagaaggt aagcaagcac
    28021 tatcatcaaa agaacttact aattggatag aagcagtaaa tgatgatttt aataatcatt
    28081 tacttacttt tcatgattac acacttttta tgattaccct gtatcttggt gatagaaaaa
    28141 gtgagactta cgctttgcaa tggaaatata ttgattttga aaaacaaacg gtccgtctta
    28201 aacatacttt agataaatat caaagaaaaa agtttacaaa aggtcgaaaa gataccgtca
    28261 ttcaagtacc agaagttgta atgacattgc taagtgaatg gaaatcggta caagctgatc
    28321 aattgttgaa attaaaaatt aagcaaacgt tagatcagta tctctttact tatactaaac
    28381 catctggaga agtaaattgt cctgttcatg ccgattacct aaactatcga atcaattcaa
    28441 ttaaaagaag gcatcctgac ttagttcatt tatctccaca caaactccgt catacttatg
    28501 caactatagc tagacaaggt ggagcagata tgaatcaaat ttcaaatgct ttaacacact
    28561 cagatatttc tacaacaaag atatatgtga acacaccaga tatagttgat aaggctgttt
    28621 ttgaagcttt tcagagagga ttgaataagt gtgattgata tgtgttctta aatgtgttct
    28681 taaaaacaaa agaagcactt tccaaataat tgaaaagtgc cagaaacgtt gatatataaa
    28741 ggatattaac gttttgagaa ttgtgaagct ttacgtgctt tcttaagacc tggtttttta
    28801 cgttcgacca tacgtgcgtc acgagtaagt aagccagcac gtttaagagc taaacggaag
    28861 tcaggatcaa cttctagcaa tgcacgagcg ataccatgac ggatagctcc tgattgtcca
    28921 gcgtatcctc cgccgtttac gttaacaaat acgtcatatg cgccttttgt ttcagtaaca
    28981 gcgaaaggtt gattgattac ttcacgcaag tcagcatgtg gaatgtattc ttcaacatct
    29041 tttttattta cagtaatttt gccagttcct ggtactagac gtacgcgagc aactgcgttt
    29101 ttacgacggc ctgtgccgat atattgaact tgtgccaatg aaattccctc ctattagatt
    29161 aagtttgtga tgtctaaaac ttctggttgt tgtgctgcat gtggatgttc tgctccaccg
    29221 tatacgttca attttgtaaa ttgtttgcgg cctaaagtgt ttttaggaag catacctttt
    29281 acagaagttt cgatcaaacg acgagaattt ttagcacgca attcgccagc agtgattgat
    29341 ttcaatcctc ctgggtagtt gctgtgacgg taataaattt tgtcagtcgc ttttttacct
    29401 gttaatttca ctttgtctgc attgatgacg atgacgaaat cgccagtatc caaatgaggt
    29461 gtgaaagttg gtttattttt accacgtagt acagatgcaa caactgttga aagacgtccc
    29521 aatggaacat cagttgcgtc tactacatac catttacgtt ctacttcgcc tggtttggcc
    29581 atatatgttg tacgcacgtt attttcctcc aatttaagtt ctgatgtttg acatacactt
    29641 cgagtttccg gggctctttg tggggcaaac aataccattt aacatattac ccgctaatct
    29701 agtcaatgtc aacgtttttc tgcttgattg aaaaatttat atgaaacttt acttcttttc
    29761 tttcttttat ataaaagggt cgtttcctgt caaaatgaaa aacaaaaaga ggctgtgaca
    29821 aaagtcttgt cacaacccct tattttgaat aaacggtgtt ctcctgccaa ctcctcggtc
    29881 acaagtcaca atatccataa aacataagaa gctgtttttt aaaattgttt cttgtgactc
    29941 ggagctgaac ggcaggctta caacctcttg gtaaacggtg ttcaatcagc tgaccctcgg
    30001 tattagctca aaaaacggca aaatatgagg aactattttg acgtttgttt ctctaatact
    30061 caggtcaaaa cgctgatttc acaacctctt tttcggtcaa gttcaacaac agtttttacg
    30121 cgtcgatctc tggcgctttg cccaaatgag cttggatcat ccagatacgt ttttctgtgg
    30181 ctgttttgaa ttcgataaag atatcttgtg ttggatcgtc gccttcttct ccagaaactt
    30241 cgattccttt ttggtaaaga tctgctagat aacgatagcc tgcaacaagt gtttccaaac
    30301 gttctggaat agtacgatcc cagcggccaa tttcatcagg gatttttgtg ttatctgcaa
    30361 attcacgcaa tgtagaataa ggtgaaccgt ctaatgtgat caagcgttcg gatacttcat
    30421 ctaactgagc gttcaaatca tccatgaact catccatcat tgggtgcaat gtaaggaaac
    30481 ctggtcctct catgtaccaa tgtgtttggt gaacaacaac agacatttgg cttagatctg
    30541 caactaattg atttaatact tctttggttt gttggaattt catctttctt gcctcctaac
    30601 attttcttac acttaaaata atagtagact ttcaatgaaa agtacaacaa aatcatttac
    30661 ctgagaacga ttttcagttc gcttttttat ccgtaaagcc aatcattttt cagaatcagc
    30721 taattcttct cgcagttgag caaattgctg ataagtctgt gctaaatgct tttgtgtcga
    30781 aacaaataat ggatagattt tctgatattt tttatgatca gtttcttgta ctccaacttg
    30841 ctctttcaat tctatcaatt cctgtgcttc actgatactt tggatctttc cgatgcttct
    30901 ccagcctaaa atcacagctc ctaatgcgga tgcttctgtg acagtaggga aaacaagcgg
    30961 gtaacccagt acatcagcca tcatctgacg aaaaatcgga gattgagcaa acccgcctgt
    31021 agcacggatc tctgtgagct gattttcctg gcaaactcct tttaaaatcc gataaaggtt
    31081 gagacagatc ccttctagaa tcgccttcat catttctttt tctgtatgtt gccgctgtaa
    31141 accgataaaa ctgccaaacg catctgcgtc ccaaagcggt gctcgctcac caagtaaata
    31201 gggatgaaaa atcagaccat tggcacccgc tggcacaaaa gcgatagccg aaagcagtgc
    31261 atcatatgga ttttctcctt tttctttagc agattgaacg acttcctgta aaaatgtatg
    31321 ccctgcccaa tcaaagatgc cagcaccatt gctagtcgct cctcccacta cccaatgttt
    31381 ctgatccaga acataacaaa acgtctccat ttctggatgg aactgaggct gagtagtaat
    31441 aaaacgaagt gctccgctcg ttcctacggt caaagcggcg atcgtatcac caaaagcacc
    31501 taaccctaga ttagaaagcg gcccgtctgc ccctcccaaa acaaatgata tatcatttgg
    31561 caaacctagt tctgctgctg tttttgatgg tagacctgtt acttgatagg tggaaggaaa
    31621 gacttgcggc aattgctcta ttcgaatgtt caagtagtca agcacttctt ctgcccattg
    31681 gaattcatgg atatcaaaat atccagttcc tgaagctgtt ccgtagtcgc tgatcagttc
    31741 gccaaacaat ctataaaaga tatagtcttt gataccgaca aaataagcag tttttttgaa
    31801 taattcaggt tggctgtttt gcagccactt gattttgttc aatggtgtca ttggatgaat
    31861 cggcgtccca gtctgccgat aaaattcttt gccaagcacg gtatatttca gtttttctgc
    31921 ttcgtccgct gctcggttat ctgcccaagt gatcattcga gataacggtg ttttctcttc
    31981 atccaacaat atcaggccat gcatcgcaga ggagaaggag acaaattgaa tgattgtgtc
    32041 tgaaggcaac tgtttaatta cttcttttat aacggtgcag acaccttgaa agatcaattc
    32101 ctgatcttgt tctgccatcc cttgtgtttc ttggatcaaa gggtagcgaa aataagcgga
    32161 tgctgcttct tgggcttcat ctgtgaaagc aactgctttg gtttgtgtgg ttccgatatc
    32221 taatccgatt gaaacgttca ttttttcacc tcaaatttta tgtatgtaca aaaatttagt
    32281 ttaagcttgc gtatcttggt tttgaaaagg gggagatggc gtgttacttt attttatcat
    32341 tggttgctgt atcggatcat ttttatgttt aaccgcccag cggattccgt taggtcactc
    32401 tattatttat cctagatctc attgtgtcaa atgctgtcgt tcgctttctt ggtatgaatt
    32461 gattccgatt ctctcgatca tcgtccaacg atttcgctgc cgctattgca ggtgtcggtt
    32521 gcccttctac tatttgttgg cagaagcctt atgtggtggt ctttttgcct ggttctttac
    32581 tttttcttcc gcaagaaatt tttcgacgtt catatggatg ctttcggctt tgctattttc
    32641 gttgatggat ttattttact tcatggtcca ttctcacacg ctattctgtt cttgggcaat
    32701 tttatggatt ttttggttgc aggccggcgt cttccaatgg caaagtgtgc tgttaacgtt
    32761 tatcgtaggc ggtgtgtgcc ttcgctatgg tcaatcctat ctcggagctg gcgatactct
    32821 gttgatgctt tcttggagtg gtggcttgtc tctagaagag ttgcttcaga tcttgtttct
    32881 tgctagtctg tttggaatat ccgttttttc tgtttacttt atctgtcata aaaaaaagtt
    32941 ggaaaagctg cctttcattc cttttttgag cagtgcgttg ctgattgtcc ttcatcttag
    33001 gtattgaaaa aaggttgtga caaacgactt gtcacaacct ctgatatata gtgttctctt
    33061 accaaatcct tgtgacttgg agctaggcga caggttcaca acctctccac taaatggtgt
    33121 tcaatcagct gaccctcagt attagctcaa aatgctggtt ttacaacctc tgatatacgg
    33181 tgttccataa gtagcttttt cggcttctta tttcttgacg ccccaatgtc gacgaaggaa
    33241 acctgcacgt ccagaacctt ctcgataaag attgtaatgg agcttgtttt tcttgtaata
    33301 atcctgatgg taatcttctg caggataaaa ttcgcttctt ggttcgattt ttgtcacgat
    33361 tggcttatcg aatcgcccgc tgtcttgcaa tgcttgtttt gaacgctctg caatatttcg
    33421 ttcttcttca tcattatagt agatcactgg acgataagaa tcaccgcgat cagcgaactg
    33481 tcctaatgcg tcagtcggat cggtttgctg ccaatagatt tccaccaact gatcataaga
    33541 aataacttct ggatcatatt cgatctctac tgcttctgta tgccctgttg tgcctgttgt
    33601 tacttgttca taagttggat ttggtacatg cccgccagta taaccggatg tcacagaaat
    33661 gatccctggc tgctcttcaa atggtttgac catacaccaa aagcatccgc ctgcgaaaac
    33721 tgcttttttt gtcatataaa atcccccttt tttctcatca taccttgatt tccaaaagga
    33781 ggataacgtt ttgcttgtga cagaaaaaac ggaaactatt atatacgtga tacggcttct
    33841 gataaatgcc aaaacgaacg tacttgatca aaaacggtta aatcaggaat cacatattca
    33901 gcagaaggaa gatttatgtt ttcacctatt cccaatacat gcatgttacc agccaaagct
    33961 gcttgacaac cagcttctga atcttcaatg accaagcatg catttggcgg tacattcaat
    34021 tgctgtgctc ctttgagaaa aacttctgga tcaggttttg cttttgatac ttgcgtgccg
    34081 tcaataagga catcaaaata acttgtcaaa ttcgtttttt ctaaaatgag gcgtgcattt
    34141 ttgcttgctg atcccaatcc gatcttgatg tttgtttttt tcaagtactc aagaacagct
    34201 attgcaccag gcaaaacgga tgtttcatcc attttttgaa tcgcttgaag atatagattg
    34261 tttttttgct cagcaaaggc tgatttctct ttttctgaga atttctgttc catttttcca
    34321 aatgacagca atcgctctag tgactcggtt ctggatattc ctttcagttg ctcgttttct
    34381 ttctcagtga atggaatgga cagctggtta gctaaaacca gccacgcttc gtaatgataa
    34441 cgagctgtgt ctacaagaac gccatctaaa tcgaatagtg ctgctttgat tttcatcgat
    34501 tacctccttg aaaatgaacg acttgaagta aagatgcgat gtttttagct gtgcgatgaa
    34561 gattatcagt ggcttgctgt aaagcttctt gtaaaggcac agctgcagga aggatcggaa
    34621 aaacggccga aatgccaaca tctgctgctt tttcgcttcc tttaccaaca cttccgcaaa
    34681 tagctatcac aggaacgccc tctggtactc ttctagcaat cccaactggc gcttttcctt
    34741 ttagactttg tccatctaga cgtccttcgc ctacgattac gaggtctgct tgctgtaccc
    34801 gtttatcgaa ctccagtaaa tccaatacgt agtcgatgcc agagactatt ttccctgaag
    34861 caaatgctaa cagtcctgca cccattccac caccagcact actgcccgat gcctcgatta
    34921 cttgaggggc aaatctcata taaaaatcat gcatggcttg gtcagccact gctaattcat
    34981 tttctttcaa gcctttttgt ggtccgaaaa caaaagaagc gccttctttt ccgcataaaa
    35041 gattagtaac atcagtaatg acagtgattt tggctttaat cagctcaata ggcacgttcg
    35101 ttttatcaac tgtagcaatt ttacctagat tttctcccag tgcttctact ttttgattat
    35161 cttgatcgta aaaagcataa cctagacctt ctgccatgcc gatgccgcca tcgttggtac
    35221 tacttccgcc aacgccgatg atgatgtgtc gaacaccttg ttgcaacaat tgtcgtatca
    35281 gttctcctac tcctcgcgtg gataacctaa gtggctgttg ttggtttagt gggacatctt
    35341 tcaatccgac gatttctgcc atttcaaaaa tcgcagtttg accgtctgaa gcgtactgga
    35401 tttctttgtt tttgccaaat gcattagtaa cgactgctgt ttgccgcttc aaccttaaac
    35461 tgtctgctaa tgatgaaacc gttccttctc ctccatcgcc tataggtagc agatcatatt
    35521 cagcctgaac aaaaacttct tgaaaacctg attgaatggc ttgtgctgcc tctaaggctg
    35581 tcagactttc tttgaaagaa tctggcgcaa tcagaatacg cattattttc ccctccgttc
    35641 caagatcagt tctttttcca gctggtattg gtctccattg acaaaaatag gtaatgtttc
    35701 tttcgtctct ttttttatta ctatttgttt ttttgtcaaa acaaatagca acctgtgatt
    35761 tttccaaata aaaggaaaag aaattttttc ccatgctgaa ggaagtcttg gagaaataga
    35821 aagagttcca ttcgttactg taatacctga aaaaccaaat ataactgcta gccatagtgc
    35881 tcctaatgaa gcagcatgaa ttccgtcatc tgatgaatgc ggatctggtc ctaaatcaat
    35941 caggcacgct tcttggaata aatgatacgc ccattccatt tcttggatac ggcaagcctc
    36001 tatggcgtga atcgctttac tcaacgatga gtcgtggatt gttttgtttt catagtaatg
    36061 caaattctta gaaacgattg gttgagaaaa atactcaggt aataagtata acagcatgac
    36121 aagatctgct tgcttgctga cttggagttc atttacttcg ctacgggcat aatcaagtaa
    36181 aatagactgg ctgccaggac gttctttgta agtggtcaaa tcaataactg gcttactgag
    36241 atacgtgtca tcttgcggaa tcagctgttc tttgttaggc actggcaaat ataacttatc
    36301 taaaaaattt tgacattctt tcaaaaaaag cggatcgcca gcttgatatt taacagctaa
    36361 ggccacatta taatgcgcca gatagttcgt atatgcatta ttgtcgatat attctgtgta
    36421 ttcatctgga ccaatgactc tgtgtatctc taaatgatca tcgactttta cagctctgct
    36481 cagccaaaaa gctgctgttt catgaatgag cgtttttccc tttgtttcta aaaacgattg
    36541 atcctctgtt gcttggacat actcttgaac ggcataagca aggtctgcac tgatatgatg
    36601 ttctgcggca gctgaagcaa cttcttgtct tgttccggtt ttgatattca atgcagcaaa
    36661 tttgggtgtc tcttcctgac cagtgtgtgc gctttcccat gggaaaagtg caccttgata
    36721 gtgataatct cttgcttttt gccgtgcgcc ttctaatcga tcataacggt acagcagcaa
    36781 attctttgct acttcaggaa actgatataa aaagaaaggc aggataaaaa tttccgtatc
    36841 ccagaaaaca tgccctttat aaccttcgcc agttagtccc ttcgccccta cactaacact
    36901 tggatcattg cggggagtca taatctgtaa atggtaagca gcgaagtcca tcgctaactg
    36961 atcgaaagaa gaatcgcctt ggatcgttat ccgatgctga tgccaaaaat ctgtccaata
    37021 agacatcgac tgctctaaaa tttctgtata actaacgctt ttctgggctt gggcaatact
    37081 tttcttaaac gggtctgttt gctgaagaga ggtagagagc acgatgatct tctccagcgt
    37141 aaaggacgta ttttttctga tcttttctga aaaggaagcg gtgatccggc gattttttgc
    37201 ttggaataca cctgctttat tgaatttagc tgcaatccca atatcaattt tactttctgt
    37261 tgtctggtag gatgcactga tcaaatcgtc accaaatact cgcagttctt tttcaaccaa
    37321 ctgctgtgta ccaaaattgg tttgctgtcc atcgataccc gttttcacat ctacttggca
    37381 gtcttcggtc aacggcttga tgaccacttt cagggctgcc tgatggagat tattttgatc
    37441 agcaacacga caagtaatga cttccacttt ttttccttga gcagtttcaa tgagcgcata
    37501 gcgtttaagc tctcccattt ctaaatctag tgcccgctcg tatgcaagaa ctttcatcgt
    37561 ctcaagagaa aaatgttcac cgtcgatttt tatttcccat ctgatgacat ctgggagatt
    37621 cactaactcg gctgattctg ctcctaaagg tcggttatat acaccagctg caaacattcc
    37681 ccttacttga ttccgatagt cttcctcctg gcttcctctg ataccaaaaa atccatttcc
    37741 aatggtcatc tgactcgcat acttattgat atactctaaa tcaaactgtt tttcttctac
    37801 tttcataagg taataacttc tcctgtttct gccgaacgat ataaattttc caccagattc
    37861 tggatgacat atccttgcca gccatctgca atcatctgag tctggtcacc gagcgcccga
    37921 ttcacaaaat gagccatact tagttcatgt gggtcattaa ctggcgtggt cttttgtaag
    37981 gaaaccagct ttccatctac atcttcgaat agttcgcctg gatacagatt agcacctgcc
    38041 tgatcgccac aaaaagccac attcagtttg tcttctctga tattcaaagc aaacgaagta
    38101 ttcagttgga tgatcttgcc gttttctaat tccagtgtgc caaaaattgc atcttctact
    38161 gtgaatttgc ttggatccca tttcccgaat ttccctgaat tttttttcgt accaattttt
    38221 tggaagctgt acgcccgaac gctttttact ttaggaaatc cagtaatata catcgctgta
    38281 tcaagcatgt gaatgccata atcgatcaaa ggcccgcctc cttgaagttc tttgtcgata
    38341 aacgttcccc agcctggaac accagaccga cgaagcgcat tcgcttctac gtaataaata
    38401 tccccgagaa catcaagatg attcttgatc attgttgctt cgtcagaaaa acgatgctgg
    38461 aatccataag ccaaaatctg cccgttttta tcggctgtct ctgccatctt tcttgcttga
    38521 tcagctgtca tagctggtgg tttctcgcac atcactgaag cattagcttc gagggcagcc
    38581 aatacatgtt cgaagtgaaa gcgattgggt gtacagacac tcacgatatc gggagaaatc
    38641 tcattcagca tttgtgtaac tgatgtatac gcatgagaaa atcctgtacg tcggcaaaag
    38701 tcttctgctc gctggctgac tggatcaacc acagcggcca attctaagac atctgatctt
    38761 ttttgataat aagcagcatg tactttttct gctacttgtc cagcgcctat gattgctact
    38821 ttcttcattt atttctccct cctttgctta tttacttatt gttattcttt ctctattctt
    38881 tctctaaatc atttaaatga cgcgctgttt ccagacagtt tttcaagtat tgcaatgatt
    38941 cctgataaat tttcacttca ttttctcctc gcaaacgaca ttcatatacc atataacctt
    39001 catactcatt ttgaagtagc gtttgaaaat ggcgagtaaa atcaattgcg ccagatcctg
    39061 gttggtagcg atgattatct gctaaatgga tatgacccac atactctttt tgcgtagtca
    39121 atgcttttga aatatcatct tcttcaatat tcatatgata aaaatcagcg atgatctgca
    39181 catgtttcaa ttgattagag tcaatgtaat gacgcgcatc cgctaacaaa ttgatcatat
    39241 ggtcttggta tcggttcaaa ggctccaaat aaataaccgt acctgtttct tcggctactt
    39301 tatctaaata acgaagtgat tcgctgactg ctttatagtc tccttctttg cttcggggtg
    39361 aaaccatcgg cggtaatcga taagtgaaca ttccccaagc tgctgggata acgattcctt
    39421 tgcctccaac ctcgcttagt gcacgcaaaa tctcagcaat ttgacgtaca ccattaagac
    39481 gccgttcttc gataaagtca ccgatccacc catcgtagcc gttacaagct gtcactactg
    39541 ggatccctgt ttctttgatt gcctgtttga ctgtgtcgat attttctatt aacaacttac
    39601 cgtcgatttc gtattcttca aatccacagt ctttgataaa tctaaatttt tctaaaatgt
    39661 ctcttgggaa aaatgcttga tcttgcgtac cgaatttcat tgttctcctc ctcggacttg
    39721 aacgcccatt ttgatacttt cttctgggtg ctggtctaca taacgcatgt aagcttctgc
    39781 gctttctgca aatggcacaa ctggatcaat gatttcttca caatccaagt aaccgttcat
    39841 caataattcc caacatgtgt cctcgattcg tttacggttc catcttgggt aatctgggtt
    39901 tggttcacta gatgctcgag caaagacgat ttttgcatta ttgaaatgtg cttcgcgacc
    39961 aagattaaac ccagctggaa aaggtttagc aaaggcaaca taagaaatga tcccgccata
    40021 gccgatccct cttaaagaag cttgtaatgc ggcagcactg ccactcgttt caataactga
    40081 atctactcca cgtttatctg tcaattcctt tagacgaaaa ccgacatctg ctttcatagg
    40141 atctagcgtg taatcggcac cgtatttttc tgctaattct ctacgctgcg ctatgggatc
    40201 gatcccaacg atggtagtag cacctgcttt tttagctaat tgaatcgcaa tttgcccgat
    40261 agcgcctaaa ccgaagattg ctacagcatc acctgctcga acatgtgctt cccggatacc
    40321 acctaaagcg aattgagcag gatcgtaaca tactgcattt ttccattgat ccaaccgatc
    40381 aagtttacgt agtttataat tatcaacacc gtttgtaatc agcgtttcac gaatgggtcc
    40441 ataagtgcag actaactctc ctttttgata ctctgtcacc aaactgcccg tttcttcgat
    40501 cgtaccgaca atcatatttc ctaattgaaa ttcgccaaat accacaccgc gttggcttcc
    40561 ttcttctctt ggcaagaata ggcgccattc ttctgaaaat tcttcatcga taaatggact
    40621 taatcctcta aagtcgacaa tttctgttcc tggttttgga gtagcgaaaa ttactcggat
    40681 acgtacttcg ttcttttcga tctcacggtc ttcgtaatct ttgaatccgg ctattcttgg
    40741 ttctaatgca actaattttt tcatcttttc tttcctcttt cttttctttt tatcctttta
    40801 cgccgccttc gactaaatca cctttaataa atcgttcaga taacgcatac ataatgatga
    40861 ctggtaaagc ggtcaccaat gaagcggcca tcattcgtcc ccaaatgtag tctggtgtac
    40921 tgaataatgt gttcaaaccg attggtaaag taaatttttc ggaggtcgac aggaaaatcg
    40981 aagcaaataa ataatcattc cacgaaacca taaagcaata aacgaagaca gaaatgattc
    41041 cagaaatagc caatggtata atgatccgaa taatgatctg gatccggcta agaccatcga
    41101 tcattgctgc ttcttcaata tcagtcggaa tcgtgtcaaa ataacttttt agcatgaata
    41161 tcgcagtagg aagtgtttga acgaccatcg tgataatcag tgctgtattg gtatcataca
    41221 aacctagacc ggaaatgatt ttaaataatg gaacaacgat caaaataccg gaaaacatat
    41281 aaacggtgta aaagctagca ttgattttcg agcgagcttt gaagcgtagt tttgacaaag
    41341 cgtatgcccc gctgatccca atcactactg cagttacgga ggctatcaag gagatcacta
    41401 aactattttt gaaatacatg atgaatggaa aaatctcagc attgaaaata tcctgataat
    41461 gttcaaaagt ccattctttc ggaaaaatag tttgtgtcgt tgcaattgct tcttgtgaat
    41521 ccttgaatga tgtcatcagc atgatcaaaa atggaaacaa attgacagct aatagcaaca
    41581 aaatcgtcgc gtaaaataag attttcctgc tctttttatt tttcatttca agtccacctt
    41641 ctttcgtgag agcaagacga ccgctgcaat aatgatgaac aatagaatcg atatagctgc
    41701 tgcttttcca agatcattga acgcaaaggc tgtctgatac aaataaacgc ctaagatatt
    41761 gactttattc gtcagtagat agacatctgt aaacatatag aacatccaga tagatcgtaa
    41821 aacaatcaca gttgctagta ctggtttgat tgccggcagt gtcacgatct tgaacttctg
    41881 ccaagcattt gcaccgtcca tttcagctgc ttcataaagc gttttgtcga ctgtttgcaa
    41941 aatagccaaa aatgaaataa acgcatacgg atagtatctc cagatagcaa acaaaacgac
    42001 cataaagaag ctagcaactg gctggtcgaa ccacagcggt gcttcgttga aaagctgcaa
    42061 cctatctact aacagatcat tgacgattcc ataactatta ttgaacatat atttccaagc
    42121 aaaaatcaaa gaaatagatg gcgtaacata acttaataaa atcagtgaac gcaccgtttt
    42181 cctaaatctg aacttgcggt taagcaaaat agctacggct aatcctaaag ctgtactgcc
    42241 tgctacaact aagaatgtgt aagcaactgt taaacctaaa gaacgataaa attcactatc
    42301 acttaaaatt tcaagataat tgcttaatcc gataaaaacg gcgtctgagt taggattcag
    42361 cggcatatcg aaaaaactga tctgaatatt ggaaagcatt ggaatcagca ctaaaacagc
    42421 taataaaagc atgcttggtg ctaaaagtcc catggctaat tttaagtcag aatgtttcct
    42481 tggacgattc attgaaacct ccccctgata atctgccaat agctatctac ttttttcgaa
    42541 caccattggc agaacttctt gttatttcgt atttttttgt gcgtcagcta aagcttgatc
    42601 gacatcttcg tttccgacag ttacttggtt cactgctttt ccgatcacac ctgagcttgt
    42661 gatatctccc attttcgtga aattcttttc cccgactagt ccaaagactt gtacttcatc
    42721 aaaagcacta gcaatctcag atggcagctc gccaaaagac ttgatgactt cattttcttt
    42781 gtaaccatcc agttcgacta cttgtttatt cactggttga gcaccaccag gagacatcaa
    42841 gacccacttt tccatgtttt tcggttgaga taagaaagct gtgaatgctt cagcagcctc
    42901 tttttgtttc tcgtctagac cagaagaaat cgtcaatcca gatactgtgc catagacagc
    42961 ttgatctttt tgtgttggga tagcaaaacc gatattttct gagttccccg cttcataaac
    43021 agaaggcaaa atgtaagttg aatagattgc cattggtgct gttccattca tgaaagcatc
    43081 tttgatttct gtcacatcat tagagcctgg catcgtgtat tgggataagt tttgataaaa
    43141 cgacaatgct tctctcatct tttccgtatc gatcgttacc tcgccttcat catccaaaac
    43201 atttgctcca tttgacaaag caaattgaga gaacgcttgc tcactcattg ttccttcagc
    43261 agtaggcata gcaattccat attgtttatt ctctttatct gtgaaatgtt gagcaatttt
    43321 taaaatatca tcccaatttt ctggttctga aaaaccagct tctgataatt tttctttgtc
    43381 ataccaaata ccttgaaccc agccgctaat tggtgcagca atatagcttt ttccatcttc
    43441 tgaacgaaca aggtttttgg ctccgtcata ataattatct tctccagctt cctcgataac
    43501 gttttggact gccgtctgat caatcagttc atctttatcc atcactttag caaaatcctg
    43561 actgacttcc attacttctg gtaatttacc ggaacgagct aacgtaacga tttttgtatt
    43621 gaacgctgat tcttctaccg gcacttgctt gattttgatg tctggatttt ctttttcaaa
    43681 atcagcaacc agttcattga tcacacttaa tcgttcctgt tcgacagaag agtgcatgaa
    43741 ttgaatcgtt gtctgttgtg attcgttaga gctttgactt tcaccacaag cagtaagaag
    43801 aaatccagta gctagcagac aggtagtaac aataattttt ttcatttttt tccacctctt
    43861 attttattat tttcagccac atatattcat acggctggaa tatcaacttt cgttcttgac
    43921 tgcaatggat aatttgtcca gaaaacaggt ctaggtaatc tccttttggt aaaagataac
    43981 ctgctgattg attggaaaaa ttatggataa ctaagacttt ctcttccttc gcttcgcgaa
    44041 taaaactgat aaaagaatct gctgagtcca gtaagtaaat caaactattc ggatggaagg
    44101 ctttttcttt ttttcgaata gatagcatct gggtcaattc accatatact gctgttctta
    44161 atggatctgt ctgcaactct ttctcaatat ctgctaacaa aaatttttgc cgattgattt
    44221 ttcgattctc tcctgttttt tctacgcctt tgtaatcatt tcgacttccc agcacacttt
    44281 gaatataaat tgccggcacg cctggtaacg ttaccaaaaa tgaatgagca gctaaaaagc
    44341 gtttgcttct ccattccgtc gtatctgttg gagaacttaa cgcatctaga tacgtagcgt
    44401 ttatctcata tggactggtc gttccatctg ggtttttctt gtagtttact cgggtaccct
    44461 ctttcttcag ctgttccact aattcaagga tcgttttttc cggcagaata cctcgtaccg
    44521 gattcaatcc gataccgtca tgggaggcta aaaaattaaa aaaagttgtt tttttcgatg
    44581 cgaaatcgat ggtttttaac cattctttca acttacttgt attacccgaa cgaatcgctt
    44641 gaagggtcaa aggtggtagc gaaaactgat agaccatctg tgcttcattc tcgccattcc
    44701 caaaataact gatattatct ttgtgtggca catttgtctc agtgatcaat accgttcctg
    44761 gagctgcttc atcagcgatt gcacggaata attggatgat tttatgcgtt tctggcaggt
    44821 gtatacaaga agttcctagt tctttccata aaaatcccac agcgtccaag cgaataaatg
    44881 aagcgccttt ttctaagtaa aacaaaagaa tatcgatcat tttcaataaa acttctggat
    44941 ttttaaaatt caagtctact tgatcttcgc taaaagtcgt ccatacgtgt ttttctttcc
    45001 cgtttttgtc aatgaacgtt gtaagtaacg ggctggtcct tggtctagtc acgctgcttg
    45061 tatctgtatc cagtggcaaa tcaataaaaa aatctttgta cgtatcattc aagtttaaat
    45121 attcctgaaa ccaagtactt tcggcagaca tatgattgca gacaaagtcg aacattaacc
    45181 gtgtttcgct tctcatttct tctatatctt cccatgtgcc caaacggtcg ttgattgcct
    45241 gataatttac aacggagaaa ccatcatcag atgtatatgg gaaaaatggc aagaaatgta
    45301 caactctaaa tgtatctgcc aaatactttt gataaaattt cttaaatgta cgcaaagttg
    45361 gttgctgctc ttcaaaaaat tgatccccat aagtaatcaa gaaaatatct tcttcgtccc
    45421 aatgcagttt gcctgcctgg cctttcttct gctgataaac actgactttt tgttcaatca
    45481 tagaggcggt tttctcagac aaatctgagt cgcgataaat cgcttgtaaa agttttgtat
    45541 acatcggatt cccctttctt ttttgggagc gttcccaacg atttgatcat attatggaaa
    45601 acgcttactg tcaatagcat ttttttaaat aattttgata tacacaaaaa tacaaataag
    45661 aaagcttatg tatcaataat taatagcttc ttaaaaaaat atggtctctc atgatcatgc
    45721 aagctattcc taaattttca aaatcataga caaaaaagaa tgtctattgt actatggaat
    45781 tattctaaaa cgctcccaaa aaggaggtgc atataaaatt gaaacctact atttatgaca
    45841 ttgcgaaaaa agctaatgtc tcaaaatcaa ctgtctccag agtattaaat aaccagccaa
    45901 atatctctga taaagcaaaa gcaagtgtac ttcaagcaat caaagaattg aattatgaac
    45961 cgagcaaaat tgcaagagga ctgtcaggaa atggttttga cgcgattcta gcattatctc
    46021 atcgtacttc tcatacgacc tatggcaatc cttttttttc agatgttatt caatccattt
    46081 ctgccgtttc tgaacaaaat aacttcgact tgattctaca aacggcaaaa acaccagaag
    46141 aagagctaga aaaatgcgcg aaaaagatcc aagaaaaaat gatccgagga attattattt
    46201 taagctctac gatggatgaa acacttcttt ttgaattgga tcaatacaat attcctattg
    46261 tggtaatcgg aaaagtcgga aacgactaca cgaacatcta ctcagtggac acggataatt
    46321 tccaggatag ttacgatttg gtggaaacac tgatcaagaa tggacaccgt catatcggct
    46381 gtctccatgc tccgacagaa gtttatgtat ccaatgatcg tctcaatggt taccgtcaat
    46441 gcttatttga tcaccaccta gatatccgta atgaatggat tatagacggc ggctttcgct
    46501 tagaagatag catggcagca atgaatgatt taatgaagct acgagaaaga ccaactgcga
    46561 ttttttctac cgatgcatta aaatcattga gtatttacaa agtggcagaa caatctggaa
    46621 agcagatacc tgatgatctt tcgatcgcag gattcagtga tcccttattg tcctccctat
    46681 tttcgccaca gttgactcgg atagacattc cgacaaatca gttaggaatc aaagccacag
    46741 aacttttatt ccaactaatc caccaccaat accctgaaga aaaaagaatc attctttcaa
    46801 ccgagattac tctcacagat tcgatccaac aacaagaaat gtagaacaga attataaaag
    46861 aacagaaaca ctgaggataa gtcagttact ctgttctttt ttcaatcact catccctcgt
    46921 taccccctcc cggtatttta gcgaattttt cttattttcc atctgtttta gatagctgtg
    46981 gataactata atgtttgtgt taaactattt tttccacagg gaagaaaaaa ctatttttaa
    47041 ccacgttgtg tataagtttt tatagttcgt ttttttaaac acatttaccc ttatttcaat
    47101 ccatgttatt tggggatact tatctctaaa acataaatag aataacagac atgtctactg
    47161 gttttgtttt attcgaggaa ttattcaata atagctagca aaatattaaa aataaccgct
    47221 ctatcttccc atcaatttat tttgcattca aaaaatgatc tatctttact tttgttgatt
    47281 gacttctctt ggaagatgat cgttccgata ccttaattgg atacgaaccg atgttgttaa
    47341 gatcctttcc cacttttctt ctagttagac aaattatttt agacaaacca aaaaagaggt
    47401 tgtgacaata atttgtcaca acctcttttt taaaatatct attttgtttg attgttcatt
    47461 gcgtcttctg cagccatttg cgcttcaata tctgaaatac tgtagacatt ttcgcttgct
    47521 acaccgactt cttttggttc catgtcacga taacgttgca taccagtacc agctgggatg
    47581 atcttaccta taataacatt ttctttcaaa ccaagaagag gatctttctt accgcggatc
    47641 gcagcatccg tcaagacacg agttgtttct tggaatgatg cagcagataa gaaactattt
    47701 gtttctaatg atgcttttgt gatacctagt aagacaggtc gagaagttgc aggaacgcct
    47761 cctgagacta gcgtattgta gttttgatct ttaaagtctg cgatgtctaa taatgtacct
    47821 ggtaagatat ctgtatcacc tggatccatt acacgaactt tacgcagcat ttgacgaacc
    47881 attacttcga tatgcttgtc gccgatttct accccttgca tacggtaaac acgttgtact
    47941 tcacgaagca agtagttttc aacagataat acatcgcgaa cttgcaacaa ttgttttgga
    48001 tcgattgatc cttctgtcaa tggtgcacca cggtggatca tatcgccttc tgctactttc
    48061 atacgtgctg tataaggaac agtatacgta cgtgtatctg tttttccttt gattgttact
    48121 tctttggtac gtgttgcagg atcttctgag atatcgatga catcccctgt tacttctgtg
    48181 atcactgctt gccctttcgg attacgtgct tcaaagattt cttggacacg aggaagacct
    48241 tgagtgatat cgtctccggc aaccccacct gtatggaatg tacgcatcgt caactgagta
    48301 ccaggttcac cgattgattg agcggcgatc gtaccaactg cttctccgac ttcaacgtca
    48361 gagccagttg caaggttgcg tccgtaacaa tgtttgcaga caccatgttt tgtattacat
    48421 gtgaagacag aacggattgt cactgtttcg acacctgcat caacgatttg ttttgcgatg
    48481 tcttcggaaa tcaattggtt tcctgcaatg atcaattcat ttgtttcagg atgacgtact
    48541 tctttacggg tgtaacgtcc cactaaacga tcttctaatg attcgatgat ttcatttccc
    48601 tcgcggatgg cttggatttc aagacctcgg tcagtaccgc aatcttcttc acggatgatt
    48661 acatcttggg ccacgtcaac cagacgacga gtcaagtaac ctgaatcggc agtcttcaag
    48721 gctgtatcgg tcatcccttt acgagccccg tgagttgaga taaacatttc caagacggat
    48781 agtccttcac ggaagttcga aatgattggc aattccatga ttcgaccatt aggagcggcc
    48841 atcaaaccac gcattccggc aagctgtgta aagttggaaa tgttaccacg agctccagaa
    48901 tcagacatca tgaagattgg atttttcgct tccaaacctt ccatcagttt ttgttggatg
    48961 ctgtcttttg cagcattcca aacagcaatg acacgttcat aacgttcgtc atctgtgatc
    49021 agaccacgac ggaattgttt tgtaatagtt tcaacttgtt tatgggcatt ttcaatgatt
    49081 tcttgttttt cattcagtac actgatgtca gcgatcccta ctgtgatacc ggcatgtgtc
    49141 gaatgtttgt accctaagtc tttcatacgg tcaagcatct tagaagtttc tgttactttg
    49201 aatcgtttga agacttctgc gatgatgttt cctaagtttt tcttcttgaa cggtaatact
    49261 aattcttgct ctttgatatg tgcaggaata tcagtaccag cttcaacaaa gtatttgtcc
    49321 ggtgtttgga cggtcaagtt gaagtctgtt ggttcattca gataagggaa ttcaggaggc
    49381 atgatctcgt tgaagatgat cttaccaact gttgtgatca tcgtacgttc tttttgccat
    49441 tcagtaaatg gtttttcacc taatgagtta gggttcacac cgatacgtga atgtaaatga
    49501 acatatccgt tgcgccatgc gataacggct tcgttttgat ctctgaagac cattccttcg
    49561 ccttcgcgtc cttcttcttc cattgtcaag tagtagttac ctagaaccat atcttgggaa
    49621 ggagtaacaa ctggtttacc atctttaggg ttcaagatgt tttgagcagc taacatcaac
    49681 atacgtgctt ctgcttgtgc ttcttcattc aatggaacgt ggacagccat ttggtctcca
    49741 tcgaaatcgg cattataagc ttcacataca agtggatgca aacggattgc gcgtccttgt
    49801 actaaaactg gttcgaatgc ttggatacca agtcggtgaa gcgtaggtgc ccggttcagc
    49861 aatactgggt gttccttgat tacgtcttct aaaacatccc atacttcgtc ttcttgacgt
    49921 tcgattttac gtttcgcatt tttgatgttt gaagctagtt cgcgttgaac aagctcacgc
    49981 atcacgaatg gtttgaataa ttcaatggcc atttcttttg gaagtccaca ttggtacatc
    50041 ttcaagaaag gtccaacaac gataacggaa cgacctgagt agtcgacacg tttacctagc
    50101 aagttttgac ggaaacgacc ttgtttccct ttcaacatat gagaaagaga tttcaatggg
    50161 cggttacctg gtccagtaac tggacgtccg cgacgaccgt tatcgatcaa tgcatctact
    50221 gcttcttgca gcatacgttt ttcattttga acgatgattc caggtgcatt caagtctaac
    50281 aaacgtttca aacggttatt acggttgatt acacgacggt aaagatcatt caagtcactt
    50341 gttgcaaaac gtccaccttc taattgaacc attgggcgta aatctggtgg aataacaggg
    50401 ataacgtcca taaccatcca gcttggttga tttcctgaag cgcggaatgc ttctaaaata
    50461 tccaaacggc ggattgcacg tgtacgtttt tgtccttgtg cagatttcaa ttcttctttc
    50521 aattcggctg cttctgcatc tagatcaaca ttatcaagta attgtttaat cgcttctgca
    50581 cccatagcag cttggaattc ttgtccatat tgttcacgtt tttcgcgata ttcgcgttct
    50641 gtcaacaatt gttttttctc taaattcgta tttcctggtt cgatgactac atatgaagca
    50701 aaataaatga tttcttccaa agcgcgtggg ctcatgtcta atacaagacc catacgtgaa
    50761 ggaatccctt taaagtacca gatatgtgaa acaggagctg ctaattcaat atgtcccatg
    50821 cgttcacggc gaactttcga acgagtaact tccactccgc atcgatcaca aacgattcct
    50881 ttataacgga tacgtttgta ttttccgcag gcacattccc agtcttttgt aggaccaaaa
    50941 atccgctcac agaacaaccc ttcgcgttca ggttttaagg tacgatagtt aatcgtctca
    51001 ggttttttta cttcaccgta agaccagctt ctgatttttt cgggagaagc caaacctatt
    51061 tgcatacttt cgaatttatt tacatcgatc aaaaggggtt ccctccattt catttaatgg
    51121 caaaccgcaa gacggctgat cttcgaccgc cttgcagctc atagaccgga ttagtctaaa
    51181 ttatcttctg cggtttcaaa gttttggatg acatcgtctt tttcatcttc cacttgttca
    51241 gcagctttct tttctaattc tttggcagtt tgctgttcgg caaattttgt caaagcatca
    51301 acagtgatca aatcgtcgtc ttcatcgtcc atgtcgcgaa gttcgatctc tgtttcttcg
    51361 atatccaaga cacgcatgtc cagacctagt gattgcaatt ctttcaccaa tacgcggaat
    51421 gattccggta cacctggttt tggaattggt tcacccttga cgattgcttc gtatgttttc
    51481 acacgtccga ctacgtcatc tgatttgtat gtcaagattt cttgtaaagt ataagccgca
    51541 ccgtaagctt ccagtgccca tacttccatt tcaccaaaac gttgtccacc aaattgagct
    51601 ttacctccca atggttgttg tgtaaccaat gagtaaggtc cgattgaacg tgcatgcaat
    51661 ttgtcatcga ccatgtgagc aagtttgatc atgtacatca caccgacaga cacacgtcca
    51721 tcaaatggtt cacctgtacg tccgtcgtac agaacagttt tcgcatcgct ggccataccg
    51781 gcttcacgaa ctgtttccca tacgtcttca tcacttgcac catcaaatac tggcgttgct
    51841 acgtggatac ctaactgacg tgcagccata cccaagtgta attccaatac ttgcccgatg
    51901 ttcatacgtg aaggcacccc taaaggattc agcatgatat cgattggtgt tccatcaggt
    51961 aggaatggca tatcttcttc cggcataata cgggatacaa cccctttatt tccgtgacga
    52021 ccggccattt tatccccttc atggatttta cgtttttgaa cgatataaac acgaactaac
    52081 atgtttacgc ctggtgacaa ttcatctcca gcttcacgag taaagatttt cacatcgtga
    52141 acgataccgc cgccgccatg tggtacacgt aatgatgtat cgcggacttc acgagctttt
    52201 tcgccaaaga tcgcatgcaa tagacgttct tctgcagata attctgttac cccttttggc
    52261 gtgactttcc ctacaagcaa atcgccatct tggacttctg caccaatacg gatgataccc
    52321 atttcgtcta aatcttttaa tgcgtcttcc ccgacattag ggatttcgcg tgtgatttct
    52381 tcaggtccta attttgtatc gcgggcttct gattcatatt cttcaatatg gatagaagtg
    52441 tatacgtcat cttttaccaa acgacggctc atgatgatcg catcttcata gttgtaccct
    52501 tcccaagtca tgaaaccaac taaaacgttt tggcctagag ccatttcgcc ttgttccata
    52561 gatggtccgt ctgccagagt atcccctttt tcgactttct cacccaaatg aacgattgga
    52621 cgttggttgt agcttgttcc ggagtttgaa cgacggaatt ttgttacatc gtatttatct
    52681 aatgcaccgt tgtcgcggcg tacgcggatt tcagaagcat caacgtattc aacgacaccg
    52741 tcatgtttac ataacaaagc agctcctgag tcatgcgctg atttgtattc cataccagta
    52801 ccaacccatg gtgcttgagg attgatcaac ggcactgctt gacgctgcat gttggcaccc
    52861 atcaaggcac ggttggagtc atcgttttcc aagaaaggaa tacatgctgt cgcaacggca
    52921 actacttgtt taggtgatac gtccatgtag tctactttat caatagatac ttctaagttt
    52981 tcactttgag cacgagccat aacaacgtct tgagcaaatg ttccatcttc attcaatggg
    53041 ctgtttgctt gggctacgat gtaatggtct tcgatatcag ctgtcaagta gtcgatttgg
    53101 tcagtaacac gacctgtttc acggtctaca cgacgataag gtgtttcgat aaatccgaat
    53161 ttatttactt tcgcataact ggacaaacta ttgatcaacc cgatgtttgg gccttcagga
    53221 gtttcgatcg gacacatacg gccatagtgg gagtagtgaa cgtcacgaac ttcataaccg
    53281 gcgcggtcac gagtcaatcc gccaggtcct aaggctgaaa gacgacgttt gtgtgtcaat
    53341 tcgccaagag ggtttgtttg atccatgaac tgtgacaact gagaagaacc aaagaattct
    53401 ttgatacttg ccacaactgg acggatattg atcaattgtt gaggtgtcaa tgtttcagta
    53461 tcttggatcg acattctttc acgaaccaca cgttccatac gtgctagccc gatacggaat
    53521 tggttttgta aaagttcacc gactgaacgg atacgacgat ttcctaagtg gtcgatatca
    53581 tcgacattgc cgataccttc catcaagttc aagaaatagc tcattgaagc aatgatgtcg
    53641 gctggacgaa ccgtttttac agctgcttct ggatagccgt ttccgatcac gtttacttca
    53701 cgttcagggt ctcttggtga aaatactttg atgacttgga cagtcattgg atctgtgacc
    53761 acaccgtctt ctgatggata gtaagtcact gaatttaggc cattatcaat gaaaggagct
    53821 agtgtttcca tgacttggtg agtcagaact gttccttttt caacgatgat ctcgcctgtt
    53881 tctggatcaa ctaatgtttc agctaatgtc agattcaata gacgtgtttt caaatctaat
    53941 tttttgttta ctttgtaacg accaacgttt gctaagtcgt aacgttttgg atcgaagaaa
    54001 cgagcattca gcaagttacg tgagctgtct gctgtttttg gttcgcctgg acgcaaacgt
    54061 tcgtaaacgt ctttcaaacc ttcttctgtt cttgagtcgc ttgcgttttt atgcaagtct
    54121 ttttcgactg tattgcgtaa tgtttcgctg tcgccgaaga tttcaaagat cgtatcatcg
    54181 gaaccaaatc ctaacgcacg aactaatacg gttaaaggaa tcttacgtgt acggtcgata
    54241 cgtacataag agatgtcttt tgcatcagtt tccatttcta gccaagctcc acggttaggg
    54301 ataacagtag aaccgaatcc ttcttttccg tttttgtcga cttttccatg gaaatagaca
    54361 cctggtgaac ggactaactg agaaacgatt actcgctctg ccccgttgat gatgaatgtt
    54421 ccttgttctg tcattaatgg gaaatcaccg aagaatactt cttgtgcttt gatttcgcca
    54481 gtctcgcggt ttgtcaaacg caatgttaca tgtaatggtg cagagtagtt tgcatcatgc
    54541 gcacgagctt ctgctactgt atactttggt tctttcaatt cataatctac aaattccaaa
    54601 gatagattgc cattgaagtc atcgattggc aaaatgtctt caaacatttc tctaagtccc
    54661 tcatctaaga accattggta agagtctgtt tgaatttcga tcaaatttgg taattccaac
    54721 acttcactga ttcttgcgaa acttctacgt tcgcgatgtt ttccgtattt tactacgtgt
    54781 ccagccaagc tcttcacccc tctaaaatgt cattcaaaaa gactacccga tcaattgtta
    54841 caataatatt tcaaatatta tttttaggta acaacagaca ttttttgcgg cttttaggca
    54901 aaaaaaaacc aaaaatagaa cattctcttg aaaccttact tcgtgagctt ctacttttgt
    54961 ttccttatat taaagccgaa acggacaata tttcgtttct gccttttctt catcagatag
    55021 tttttgcaac ttcatatact acacttattt tctataaaag tcaacacttc ctggcgtttc
    55081 ttctgctttt tcgcaacatt ttcttaatgt tttcaatttt atgttttcaa ttatctgaca
    55141 attcttaatt gacagacctt tttatctcgg ttatacttta gaaaattcat tttgtggagg
    55201 aacttctatg cgaaccaaca tcaaccaaat cgcaccaaca caactgaata acttttactt
    55261 tagctacttt agataggttt gtattcatca tgatggatac aaacgttaaa cgacagtttg
    55321 tatctatgat ggctaaagaa ctttgtattg cagcaaaaag ccacgtagac aaaatgctaa
    55381 gtggctgagc agtgaaaata caaagtaaaa gtatcaagca ttctactttt tcaatttatt
    55441 ttccgacttt tcaatccatt tggacatttt gtctgaatgg attttttgtt tcccaaaatt
    55501 aaggaggaaa aagaaatgaa aaaaaatata atcatcggat taggcgctgc cctgctacta
    55561 gctttaggag gttgcgcaca aaaagacaat tccgcagagg catcagatgg acaaaaaaca
    55621 attggcgtat tgcaacttgt acaacataac tcgttagatg ctgcctataa aggattcaaa
    55681 gaaggattag cagaagaagg gtataaagaa ggcgataatc taacaatcga ttatcaaaat
    55741 gcccaaaaca atcaagacaa cctgaaaagt atgagtgaga aactcgtcaa agaagatcct
    55801 gatttgctac ttggaatcgc cactccagca gcacaatctt tattaaatga aacaaccact
    55861 atcccgatga ctgtcacagc ggtcacagac ttggaacaag cccatttagt cacatccaat
    55921 gaaaaacctg gcggcaatgt gactggcacg acagatatgg tgccaatcga aaaacaaatc
    55981 ggcttactgt taaatatcgt gccagacgcc aaaacaatcg gcatcatgta taacaacggt
    56041 gaagcaaact ctaagatcca agctgatttg gcagaaaaag aattgaaaaa agcgggcgtc
    56101 aaagtcaaag tactgacagc aaattccaca aatgatgtcc aacaagtgac gaaaagtcta
    56161 gctaaagatg tagatggaat ctatattcct actgataaca cgttcgcaag tgcggcaagt
    56221 gttgtcggtg aagtcgcaaa agaaacaaaa acacctgtcg ttgctggcgc agttgatcaa
    56281 gtcaaagacg gcggtctagc aacagtagga atcgactacg aaagcttggg taaacaaaca
    56341 gggatcatgg cagcaaaaat cttagacggc aagaatccaa gtgaacttcc tgtcgaaaca
    56401 gcgaatgatt tggaactgta tgtcaataaa gacatggcca aagcattagg catcaatcca
    56461 gacagcatca aagaagctga ataaaacaca ggaggattct catgacaaat ttgctctctc
    56521 ttttcttatc atctgcatcg caaggggtct tatgggccct acttgcgatt ggtgtatacg
    56581 tcactttccg tatcttggac attgccgact tgactgctga aggaagcttt cctttaggtg
    56641 cagggatcgc ggcagtaagt attacaaatg gctatcatcc attgacagct tgtcttctag
    56701 gctttttagg gggtgcggca gcagggcttg tttccggact gcttcacaca aaattgaaaa
    56761 ttcccgccct tcttgcaggg atcatcacca tgactggttt atattctgtc acatcccgtg
    56821 tgatgggtgc gccgaacatc tctttattgg gtcagccaac gatctttcat tgggtcgagt
    56881 cattcggcat aacaaaagac aacgctgtac tgatcgtcgg tctgcttttt gctttgatcg
    56941 ttgtatgttt acttgttttg ttcttacgta cagaaacagg acttgctatt cgtgcaactg
    57001 gcgataatct ggcaatgagc gaagcaaacg ggatcaacac agataatatg aagatcatcg
    57061 gttatatgat ttctaatgga tgcattgctc tttctggctc cttgcttgcg caaaacaacg
    57121 gctttgctga tttaaattct ggtattggaa cgatcgtaat tggacttgct tctattatca
    57181 tcgcagaagt tttgttacgt aaccagccac tatttctccg tctcttgact gtcgttttag
    57241 gtgcggtcat ttatcgtttt attttagcgt tagtcttcga actgaatgtt gaaccaagtg
    57301 attcgaaact tgcttctgct ttcgtgctag tgatctgtct ttctttcccg cagatccagc
    57361 aaaaattcca tttacctcaa aaaaagaaag gcggtagtgt caaatgaatg acgtcttaac
    57421 attggaaaat ctccatcata cctttgaaaa aggaacgatc aacgaaaatc atgtcctgaa
    57481 aggcattaat ctttccttag atcccggcga cttcgtgacg atcatcggtg gaaatggggc
    57541 tggtaaatct actttgctga acagcatcgc cggtacattt tctgtcgatc agggtcaaat
    57601 tttattgaat ggaaaaaata tcacgaaaaa atctgttgtc gaacgttcga aatccatcag
    57661 tcgcgtattc caagatccta aactagggac agccgttcgt ttaacggtag aagaaaatct
    57721 tgctcttgct atgaaacgag gaaaaaaacg cggcttcttc cgtggtgtca aaccacaaga
    57781 ccgaacattt ttcaaagacc agctggttcg gctaaatttg gggttggaaa atcgtttatc
    57841 ctcagaaatc ggtttgctgt ctggaggaca acgtcaagct attacgttat tgatggccac
    57901 attacagcgt ccagaactga tcttattaga tgaacacact gcagcgcttg accctgctac
    57961 ttccaaaacg gtgatggaat tgacagaaaa gctgatcact gagcagaatc tcactgcttt
    58021 tatggtcact catgacatgg aagacgcgat ccgctatggg agtcgactga tcatgctgca
    58081 tcaaggaagg atcgtcgtag atatccagca agaggaaaaa cagcagctca cagtgcccca
    58141 attattagcg ttgttcaaac aaaacagcgg cacggcatta aaagacgatc aagtactttt
    58201 atcttcataa tcagaaagag gatgggacaa aaaatgaacg cccaccctct tcttttttct
    58261 ctttccttct ttcgtttttg ctttatgtat caaccgttgt ttcttcgaaa actattttgt
    58321 tctctccttc ttcctgatag aatggatggg aaaggagctt gatgccatga caacgaaaga
    58381 caaggtactt caattattga aaaagacacc agattttctt tccggagaaa agttggcaca
    58441 gcaactggaa gtttcccgga caagtatttg gaaagccatc aaagaattgg aaaaggcagg
    58501 ctatcgtttt gagcacgggc ctacagggta tcgttacctg ccctctgacg tactagatgc
    58561 aaaagaaatc cagcaagagc tacggtcgtt tattcctgat ttgaaagtac aaacgatgtt
    58621 gacttctgaa tctacgatga aagatgtcaa actggcagca gctcaaggag attctgtttc
    58681 gaagttattt gttgctgata cacaagaaca agctcgtgga cgttttggac ggcctttttt
    58741 cgctgaacct ggacgaggaa tctacatgag tctcttgctc catccagaca aacggtttga
    58801 tgaattgcct caatatacga tcatcgcagc cagtgcctgt gtgaaagcca ttgaatctgt
    58861 aaccggtcgt tctgcttcga tcaaatgggt caatgatatc tacatggatg gaaaaaaagt
    58921 ctgtgggatt ttatctgaag cagtcagtga tatggaaagc ggcaggatca gtcatatcat
    58981 cattgggatc gggcttaatt tttctgttcc tcaaaatcat tttccagctg atctccaaga
    59041 aaaagccatc tctgtctttc ccgacggaca agctagtgtc acaaggaatc agctaatcag
    59101 caaaatctgg caagaattgt tcacttatct ttctcaccca gaaaaagcgt tggacttcta
    59161 taaagaaaaa tcattcgtat tgggaaaaac cgtgtcgttc aatcaaaaag gaacgactta
    59221 tgtcggtctt gcaaaagaaa tcggtgatca tggcgaactg atcgtccaaa caaatgaaca
    59281 gaagatgagt ttgtcttctg gcgaaatcag tctcacatct atccgtacgc aataattatc
    59341 agatttcaca aaaggacacc tgatctcata cagtgtcctt ttttctgaat tctcttcaaa
    59401 agactctcct tattctatca gctgacagtt tctctatcct ctagaaaaag gtattctaaa
    59461 aatatctata aagcatggta cactttcttt aaatgaatca atgcaaaaaa caagagagtc
    59521 atcagtttac acgatcaaaa gagatagcag gccgcttcct ttttcaatct tatagataga
    59581 ccatgggtaa cgataaaaac aaaaaagaac ttgcgactta ttttgccgta agttcttttt
    59641 tagctagtgc cttaatctct taatcccaac aaacgtctcg catagatcac ctgaccagag
    59701 tgcatagcag catcatcaat aatagaaacg agacgcattc ctcgtgtgac tggtggtgtc
    59761 cagttctcgt caattacttc atctagctcg gaaggttcca gccttcttaa gtaagaaata
    59821 gcaaaatcag cagctcctcg caagtatcct agcagatctt ctatttgatt agcttggatc
    59881 tgctttgctt gttccagact atgcttccaa tcttgttcgt tatctgctat cgtcatcgga
    59941 aaccggcttt cccagtcttg actatgccaa attggagaag ttcctgctaa atcagcaatc
    60001 tggaaatcta attctcgagc ggtatgccaa gccagccaag tcattgattt gatctgcggg
    60061 gctctatctt ccactggaaa acgattggcc tcctcaatag agacgccttc aaacaaacgt
    60121 tcaaaccgat cgtatgcccg atccacactc tcgcatagca tatctaaata atccatttat
    60181 tttcctcctt tttatttatc ctacttactt tttcctaatt ctaggatacc tacttatatg
    60241 ttactacaca cccttatttt ttacacttta acagtcacca tcatcaatag tttggagatt
    60301 gaaagaaaaa gatagtgtcg aactatcaat tgaacaagaa gcaacaatat gaacgtttca
    60361 ttaatattct ttaaataaac aatgattttt caaacgaaca gtttaagact aggagaaaaa
    60421 gagtataata ggaaaatgtt tgaaaggaaa ggaaggggaa aaatgaaaaa aagggcaagt
    60481 ttactagtcc tagttgcttt gttgttcaat atcttttcgt atggtgtggc cgtttcagcg
    60541 gaaacataca ttcctaaaga ccctgggaat atttataatg atctaactgg taactatggc
    60601 ttgttaggaa ttgctagtca attccacgta tttgctaaaa ataagacaac tgtgaatgca
    60661 catacagacg gaaatatagc aacacatgaa cttgatgcaa aaaataattt tggtacagag
    60721 cttcatgaag gtttattgaa ccaagaaata aattatatac aaaaaactga ttctttcgct
    60781 aattcttcag gcatacctac aggtagcaca agaatgaata aatttgtcgt tggcagtaac
    60841 gtggatgtag cacttcaaga tggtcatcct acagtcaatg gatccaggct tgatcactta
    60901 actccagatg atttttataa agatcgtgct gggcatgaat atattgattt cgagcaggaa
    60961 tttgctaaat tgaatgtagc agcaaatgat cttgcaacga tcactccagc taaaacatat
    61021 actgctgcag attttccaga catgaacaat cggacaatcg atttaactga tttatcagat
    61081 accgggtttt tattggtaaa tatcgatgca gaagtgttaa cgatgaatac gccacttcaa
    61141 atcattaatc caaatgatca agtagttgta tttaatgtca tcaacagttc ttctgcattg
    61201 aacgtacagt caccaatcaa atacaatgat cgttcaaatc atgaaacaga agatttttcg
    61261 gatgcgaata tctcttggaa ttttggaaat gagatgactg atttgacaat cagtgctcct
    61321 tttcaaggaa caatccttgc gcctaatgct actatccgca ttactcaaaa ccaagacgga
    61381 acgattatag gaacaaatgt gattttagat gcagctacca atcgttggga tcctaacgaa
    61441 atatttatca gcgacaatgg tacagatacg acagacacaa gcgacagtac agatacatct
    61501 accacaagtg atagctcaga ttcatca
//
LOCUS       DADLIO010000009        55470 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.009, whole genome shotgun sequence.
ACCESSION   DADLIO010000009 DADLIO010000000
VERSION     DADLIO010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 55470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55470
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.009"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(75..1442)
                     /gene="nhaC"
                     /locus_tag="JOX41_000691"
     CDS             complement(75..1442)
                     /gene="nhaC"
                     /locus_tag="JOX41_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HAY6448457.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(1551..2972)
                     /locus_tag="JOX41_000692"
     CDS             complement(1551..2972)
                     /locus_tag="JOX41_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAY6448458.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(3215..5092)
                     /gene="tdc"
                     /locus_tag="JOX41_000693"
     CDS             complement(3215..5092)
                     /gene="tdc"
                     /locus_tag="JOX41_000693"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HAY6448459.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(5383..6639)
                     /locus_tag="JOX41_000694"
     CDS             complement(5383..6639)
                     /locus_tag="JOX41_000694"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HAY6448460.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     gene            7219..8520
                     /locus_tag="JOX41_000695"
     CDS             7219..8520
                     /locus_tag="JOX41_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAY6448461.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(8589..9188)
                     /locus_tag="JOX41_000696"
     CDS             complement(8589..9188)
                     /locus_tag="JOX41_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAY6448462.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            9442..10323
                     /locus_tag="JOX41_000697"
     CDS             9442..10323
                     /locus_tag="JOX41_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6448463.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            10336..11946
                     /locus_tag="JOX41_000698"
     CDS             10336..11946
                     /locus_tag="JOX41_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HAY6448464.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(12023..12682)
                     /locus_tag="JOX41_000699"
     CDS             complement(12023..12682)
                     /locus_tag="JOX41_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAY6448465.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(12965..13630)
                     /locus_tag="JOX41_000700"
     CDS             complement(12965..13630)
                     /locus_tag="JOX41_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448466.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(13777..14382)
                     /gene="dhaL"
                     /locus_tag="JOX41_000701"
     CDS             complement(13777..14382)
                     /gene="dhaL"
                     /locus_tag="JOX41_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HAY6448467.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(14410..15393)
                     /gene="dhaK"
                     /locus_tag="JOX41_000702"
     CDS             complement(14410..15393)
                     /gene="dhaK"
                     /locus_tag="JOX41_000702"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HAY6448468.1"
                     /translation="MKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRVVAKNQKAEQ
                     VGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEADSGKGVLLIV
                     KNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAGTVLVHKIVG
                     DAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDEIEYGVGIHG
                     EPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQFVFMNDVLA
                     LLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTISW"
     gene            complement(15395..15790)
                     /gene="dhaM"
                     /locus_tag="JOX41_000703"
     CDS             complement(15395..15790)
                     /gene="dhaM"
                     /locus_tag="JOX41_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HAY6448469.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            15944..16264
                     /locus_tag="JOX41_000704"
     CDS             15944..16264
                     /locus_tag="JOX41_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HAY6448470.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(16376..17245)
                     /locus_tag="JOX41_000705"
     CDS             complement(16376..17245)
                     /locus_tag="JOX41_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAY6448471.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(17341..18645)
                     /locus_tag="JOX41_000706"
     CDS             complement(17341..18645)
                     /locus_tag="JOX41_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAY6448472.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(18642..19151)
                     /locus_tag="JOX41_000707"
     CDS             complement(18642..19151)
                     /locus_tag="JOX41_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448473.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(19326..21461)
                     /locus_tag="JOX41_000708"
     CDS             complement(19326..21461)
                     /locus_tag="JOX41_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAY6448474.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(21544..23199)
                     /locus_tag="JOX41_000709"
     CDS             complement(21544..23199)
                     /locus_tag="JOX41_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAY6448475.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(23201..23515)
                     /locus_tag="JOX41_000710"
     CDS             complement(23201..23515)
                     /locus_tag="JOX41_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAY6448476.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            23685..23945
                     /locus_tag="JOX41_000711"
     CDS             23685..23945
                     /locus_tag="JOX41_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HAY6448477.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            23959..24273
                     /locus_tag="JOX41_000712"
     CDS             23959..24273
                     /locus_tag="JOX41_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur reduction protein DsrE"
                     /protein_id="HAY6448478.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(25003..25557)
                     /locus_tag="JOX41_000713"
     CDS             complement(25003..25557)
                     /locus_tag="JOX41_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HAY6448479.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(25683..27612)
                     /locus_tag="JOX41_000714"
                     /pseudo
     CDS             complement(25683..27612)
                     /locus_tag="JOX41_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(27918..28634)
                     /locus_tag="JOX41_000715"
     CDS             complement(27918..28634)
                     /locus_tag="JOX41_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HAY6448480.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(28635..30458)
                     /gene="glpO"
                     /locus_tag="JOX41_000716"
     CDS             complement(28635..30458)
                     /gene="glpO"
                     /locus_tag="JOX41_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HAY6448481.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(30472..31968)
                     /gene="glpK"
                     /locus_tag="JOX41_000717"
     CDS             complement(30472..31968)
                     /gene="glpK"
                     /locus_tag="JOX41_000717"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HAY6448482.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(32104..33564)
                     /locus_tag="JOX41_000718"
     CDS             complement(32104..33564)
                     /locus_tag="JOX41_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAY6448483.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(33554..34849)
                     /locus_tag="JOX41_000719"
     CDS             complement(33554..34849)
                     /locus_tag="JOX41_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAY6448484.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(35181..35858)
                     /locus_tag="JOX41_000720"
     CDS             complement(35181..35858)
                     /locus_tag="JOX41_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HAY6448485.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(35888..36979)
                     /locus_tag="JOX41_000721"
     CDS             complement(35888..36979)
                     /locus_tag="JOX41_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HAY6448486.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEKAYKELYLPSPLYNFLKARYQ"
     gene            complement(37080..37514)
                     /locus_tag="JOX41_000722"
     CDS             complement(37080..37514)
                     /locus_tag="JOX41_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAY6448487.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(38098..39555)
                     /gene="ascB"
                     /locus_tag="JOX41_000723"
     CDS             complement(38098..39555)
                     /gene="ascB"
                     /locus_tag="JOX41_000723"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAY6448488.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(39552..41447)
                     /locus_tag="JOX41_000724"
     CDS             complement(39552..41447)
                     /locus_tag="JOX41_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAY6448489.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(41505..43280)
                     /locus_tag="JOX41_000725"
     CDS             complement(41505..43280)
                     /locus_tag="JOX41_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAY6448490.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(43330..44826)
                     /locus_tag="JOX41_000726"
     CDS             complement(43330..44826)
                     /locus_tag="JOX41_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAY6448491.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(45020..46642)
                     /locus_tag="JOX41_000727"
     CDS             complement(45020..46642)
                     /locus_tag="JOX41_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HAY6448492.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(46970..48283)
                     /locus_tag="JOX41_000728"
     CDS             complement(46970..48283)
                     /locus_tag="JOX41_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAY6448493.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(48528..48752)
                     /locus_tag="JOX41_000729"
     CDS             complement(48528..48752)
                     /locus_tag="JOX41_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448494.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(48772..49140)
                     /locus_tag="JOX41_000730"
     CDS             complement(48772..49140)
                     /locus_tag="JOX41_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAY6448495.1"
                     /translation="MIQKTRVMLYVNDVEMICRFFVEKIGAEISETIELPEEFKSIVL
                     SISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETIYENMEEPGEITDNNGILT
                     FNFSDPEGNYFVIGKAESSD"
     gene            complement(49336..50046)
                     /locus_tag="JOX41_000731"
     CDS             complement(49336..50046)
                     /locus_tag="JOX41_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448496.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(50064..50561)
                     /locus_tag="JOX41_000732"
     CDS             complement(50064..50561)
                     /locus_tag="JOX41_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAY6448497.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(50598..51050)
                     /locus_tag="JOX41_000733"
     CDS             complement(50598..51050)
                     /locus_tag="JOX41_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003331879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAY6448498.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(51185..51790)
                     /locus_tag="JOX41_000734"
     CDS             complement(51185..51790)
                     /locus_tag="JOX41_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAY6448499.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(52240..52860)
                     /locus_tag="JOX41_000735"
     CDS             complement(52240..52860)
                     /locus_tag="JOX41_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAY6448500.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(52862..53731)
                     /locus_tag="JOX41_000736"
     CDS             complement(52862..53731)
                     /locus_tag="JOX41_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HAY6448501.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(53754..54161)
                     /locus_tag="JOX41_000737"
     CDS             complement(53754..54161)
                     /locus_tag="JOX41_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAY6448502.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(54180..55469)
                     /locus_tag="JOX41_000738"
     CDS             complement(54180..55469)
                     /locus_tag="JOX41_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAY6448503.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
BASE COUNT        15780 a        11768 c         9549 g        18373 t
ORIGIN      
        1 aaaagcaatt ttcttgagtt tcttcttatt tcttggagtt aaacgcttct gtcccagcct
       61 cttttttcct tccttcaatt ttttacacgt cgacgattca ataaaaaacc gcctaatatt
      121 gtaaagacag gtgcaagaat cgagaaaaag gcgaatggca agtaatgcaa cgcgctaact
      181 ttcatcgttc ccataatgaa tgtgccgctg actccccacg gtacgagaga attgacggtc
      241 gcacctgaat ccgctagtgt tcgtgtcaaa taggtttttg ataagccaac gtcatcaaaa
      301 gaacgcttga atgtttctcc tggaagaatg atggacagat actgttctcc aacgatcaga
      361 ttgattccga tacagctcaa ggcagtaaac ccgactaaac gagaaggtcg gtccatcttt
      421 tcttttaatt cttgaacgat ggtatcaacg atcagatatt tgatcagtaa cccacctaat
      481 gccaatgcaa gtaaaatcaa actagcagaa cctaacatac tcatgatccc gcctcgagaa
      541 agcagttcat ctagctttgg atcaggtgta tttgcgacat aaccattcat caagatgtct
      601 gctgcttttc cgaccgtcaa acttttctca tggataaaag aaagaacgag agcagctgtc
      661 gatcccgcta gtaatgtagg gatagccgga atttttttga ttgccccccc aaataaaata
      721 actagtggaa tcaatgtcca aggagagatc caaaagctcg ctttcatgtt ttggatcatt
      781 tcattgatac tagctagatc ggctgaatga ctgttatgtc ctaatatcgt ataaaaaatc
      841 aacgaaagga cgaatgctgg gaaatccgta taacgcatac cagcgatatg ttcgaataga
      901 ttaactcctc caatacccgc tgccaagttg gtcgtatctg ataaaggcga gcagttattc
      961 cctaaaaagg caccggaaac gactgcgcct gtagtcattg catcattgaa tccaagtaaa
     1021 tgaccgatcc ccaaaaaagc aattccaatc gtcgaaatcg ttgtaaatga actgccgaca
     1081 gtcactccga caattgcaca aacaagaaat gctgtcggta aaaagaaacg cacagaaaca
     1141 agtttaaatc cataaaccat aatcgtaggg atggttccag ataaaatcca tgaagcaact
     1201 aagacaccaa tcaaaagaaa aatcaggatt ggaatgatcc ctggagtgat tcctttgatg
     1261 atcccgtcat ggatctcatc ccatgtgaac tttttaaatc tgccataaaa caacaaacac
     1321 atgaaagctg caaggatcgg gatatgtggc gagagctgga atccgatgat cagtactcct
     1381 aggagtgcca acaacacgat caatacagcg atactttctt ttaaagaaat atttttattc
     1441 atcgtcgatc tcctatttca aatgaaaagg ccctgccatg aaaaaactat tcacttggca
     1501 ggacctccta ctaaatcagc gacaaaacgt cggctgaaag acttattttt ttatttttct
     1561 tctaaacttt tttctacctc aatcccccaa gaatctttct tgaagtgatt gatgatcaat
     1621 ggaataacga acatgaccac tgtgatagct gctactaata atgcatcact caatgtcgct
     1681 gtacctaatg tagcaaatac gacaacgatg atagagaaga tcagcatgca gctgactacc
     1741 caagctaatc cgtttccgtt tttaccaatt cggtaaggac gttcgaattc tggatgtttc
     1801 ttacgcattt taagcaatga aacagcaatc aaaatgtaca cgatacaata aataacagtt
     1861 gtagcatttg taagtgtcaa gaatacagca cttacgtcat ccattacacc ataaagcaaa
     1921 gcaaataatg aaataacgat tgattgtgtt agaacgacat ttctagatac gccgtatttg
     1981 ttttctttat ggaatccgaa ttttggtgga aggaatcctt cacgagctac ttggatgatt
     2041 gtttttgatg gtccagtaac ccaagctgat aattgtaaaa gcacaccaat aaataccatg
     2101 aagctgaaga tatttccgat cacttctggt aagcctagga tttgacagtc aatcaagata
     2161 ggctgcgtga tatttgctaa ttccattttt ccatctggta cgacatttgc tacaagcatc
     2221 gcattgatga cattcaataa aactaatccg atcaaagcga taaatacgcc ttttgtataa
     2281 ttttttgttg cgtctttcaa acgaggcatg taaacagaac tcatttcgat cccaacaaaa
     2341 ataaatgtga taccagctaa gtatttcaat gaatcaatat gttccaagtc agggaaagct
     2401 tttgaccatg aaaagtcacc tagatagccg tttgagacta gtccgacttt gaaggctgcc
     2461 aaaacaccta aaacgaacat gatgactact gggatatata cccctagcca tacaccgatg
     2521 ttcccgccga cttttgccat atcgaatttc aagttcaaga tcgtgatgat ccagtagata
     2581 actaaaatac aacctaaaac gaaccagtga ttattgccaa gttctacatt accaaatgtg
     2641 tttcctaaca atggtcctaa agtagaagcg accattacca tacctgggaa catttgcacc
     2701 cataatagcc atgcaacgac aaatccccat ttgctgccca gtgctgtttt tacccataac
     2761 tgaggaccgc cttcttgagg aagcatcgtg gaaagctcac cggaaaccat tgatatcgga
     2821 ccggcaaaaa acaaaactgc aaaaattgaa taaaaaatca atgtccaacc gactgcggct
     2881 aacgtaggaa tactccgaac cgttgcacac agtgccattg tcagaccgat aaaggtccca
     2941 agacccattt tacttacttc agatttactc accgttgaca ctctccttga ttttttggat
     3001 aaaataacgg tgtctttgaa gtagtttcag caataaacga aacaattcag cgaatatttg
     3061 aggggattct ttgagtttat tgcttgaagg gtttcttcaa agacaacctc aaaacaaagg
     3121 gatcgaagag cttaggtctc cccttgctct tcagatccaa acatgcgtca gaaacagtta
     3181 gtattcaagc tgttttctaa catgattacc ttgcttattt tgcttcgctt gccaataatt
     3241 ggtctgcgta gattttttcc aatttttctt gaagagctgc tttgattttt tcagcatatt
     3301 cttcaaagtg ttcttctttg ttcatgtatg gtgtcattac gctggcacgc aatacagtta
     3361 cttttccggc acggttccat tcttcatctg agaatcctag ttggttcaca aattgtaatg
     3421 ggctgttgcc atagtctggg atagcaaagt cagtatgtga agttaagaac tcattaccgt
     3481 aaatgcttcc tttcacgtat gaagaataat catatacgtc atggttcaat ttattcattg
     3541 caactaagtc atcgttgcct ttttctttga atacatagtc taccatattg aaatctggat
     3601 aagttaatgg atgaacttcg atttctttgt ctcctacttt aaatgacaag tcattcaaga
     3661 agttgtagaa acgatgtgca ccttcgattg atgcacccat taatttacca tatcctgtga
     3721 cattcaaagg taagacatgg tgtgctgccc aaacgctggc tgctgttgcc cctgcttttg
     3781 aaccttccaa gatataagcc ccaagtaatg ctgggatatc tgcgcctttt tcaaatacat
     3841 atgtcgcaaa gtaagagata acgtctctca tgcggatatc tttgatgacg ataccaccgg
     3901 cagaatatgg aacatagccc attttatgtg ggtcaatcgt tacagattct gcttcttcga
     3961 ttgctttata tgcactgtgt acttcttcta agatataatc tttgttttct gtaaagacat
     4021 tgtatttgta atgaacatct tttaaatctt caaatggaat gaagttgttg tcttcgtcta
     4081 agaaaatcgc acggccgtat ccgccataag cagcatctac gtgtaagtag aagtaaatac
     4141 cgtctttttc taatacgcga cgcaatgcaa cgattttatc gataccgtcg attgctcctt
     4201 cttctgttga tcctacaaca ccgactacac ctaggattgg tgttttttca gctgctagac
     4261 cacgaacgat tttttcaagt tcgttgatgt ccatgcgata gttgtggtca actggcactg
     4321 gaatcacttg gtctaaaccg ataccgatga tgtcggcagc ttttagccat gaatagtgtt
     4381 tagtttgtgg aaccaaccat tttcctaatt tttctaaatg ttttccgcta cgtgctgagt
     4441 gagctttgat ttcgtcgatt ttttctggga cgctgtctaa cagattcatg atttcttctg
     4501 ttgacaagtt cattaattcc caatcgcttt ttccagcaac tagttcaggt gtcacttctt
     4561 tcattgcaag cggcaatgat ttgatgttgc gggcatacca aagtccttct aagtttgcta
     4621 aagaaccatc agcaacgatg tggccccagc catctttata gctcattaat tttgcaaatt
     4681 ccattcctac ttcttcttcc atttggcttg ttgcaggaga agattcatag gcaacgttat
     4741 taccattcca tagcatagca aaattgtacg ctagtaaaga tggcatcaat gtttcagagt
     4801 tcatatgacc ccagtaacgt ccggcattat gccaaggaac ggaatgggta cgcatccgcg
     4861 ctgaaatttc tgatagaaca tcctttgttt tattcacagt gtgttcaaaa ctagcactgc
     4921 ttttttcttc tggcgtaata ataggcatgt cttgaggcat gtagttttga cgccagccta
     4981 aatgttcatc caccaattca ttcaacaaag ctttatagat ttggccgttc tcagctttgt
     5041 ccccaatgaa tagggcattt aggtttagat ctttcgacaa tgattcactc atagtgaaac
     5101 cctcctaaaa aaatatttaa attttgtcga gccctacatt acacctgttc ttctattctg
     5161 taaactaagt tttggcctga tttttaatca tattttaata tgtatcaatt atccgaattg
     5221 ttcacacttt tgaaataatt aaaaaaaacg agggaattta caaatgtaaa ctccctcgca
     5281 aagattgtat taacgacaac cagcgttcta ttttaggatg ggtttcaaaa ttggaatgtt
     5341 gtaatagtat ttcccttttt caaggtaaaa acttactaaa ttctaatcaa ttactttggc
     5401 caaaaagtaa tttttcttac cttttcgaat aaccacaaac ttaccatcga attcatcgga
     5461 tggatttatg acaaaattta aatcggtaac gcggtcaccg ttaatactta tagctccgtt
     5521 tgaaacatct tcacgtgctt gacgtttaga tggttcaatt tttgtggaaa caagcagttc
     5581 cacgatattt tcaggtgtgc ttgaaatttc aacgttcggc attttaccga atccttgcgc
     5641 gatttcttcc gcatttagtt ctttaatatt tccagagaac aatgcttgcg ttattttttg
     5701 cgcttctttc aagtcttctt cactatgcac aaatcttgta acttcttctg ccaaacggcg
     5761 ttgtgcttca cgtttctcag gttctgtctc tacttttttc gctaagtctt cgatttcttc
     5821 ttgagacaag aaagtaaaga atttcaagta tttcactaca tcgcgatcat cttgattcaa
     5881 ccagaattgg tagaactcaa atggtgaagt tttcttcgga tcaagccaaa cggcaccgcc
     5941 tgcagttttt ccgaatttcg ttccgtcagc cttcagcatc aatgggatcg ttaaaccgaa
     6001 cgcttctgct tctggtcctt ctaattttcg gattaggtct aatccagctg tgatatttcc
     6061 ccattggtct gctccaccga tttgcaattg cacatcgtat gttttatgca gatgcaaaaa
     6121 gtcgatagat tgcaggattt ggtaagtaaa ctctgtaaat gagattccta cttccaaacg
     6181 gctggcaacg atatcttttg ctaacatcgt gttgatgttg aagtttttac cgtagtctct
     6241 caaaaattca agtaaagaga tttttgacaa ccagtcgtag ttgttcacaa atgtgatatt
     6301 tgcatcttta ccaaacaatt ttctcatttg attggaaagt gcgtccacgt tatgttgcac
     6361 ttgttccatc gtttgcaaca cacgttctgt tttgcggccg cttgggtcgc cgatcgttcc
     6421 tgttccgccg ccaatcagaa tatatggatg atggcctgcc aattggaatc ttttcatcat
     6481 cataaatgga atcaaatgtc cgatatgcat cgaatcacca gttggatcaa cgccgcaata
     6541 aagtgaaatg ctcttttctt caacgagctc gcgaagtctt tcttcgtttg tttgctgatt
     6601 aatggcgtcg cgccaagtta attcatcaat aatattcatt ttactgacct ccgtgtagtt
     6661 tttttatgaa agcaggaacc tgctagcata tgtaattaat tatttcttca ggataggata
     6721 ggaaataaaa aaagtccctt ggcatataag ccaagggacg aaatctcgcg gtaccaccca
     6781 atttgtatgt ctagatatcc aacatacctc tcgaacattt aacgctgtcg cgtggcaatc
     6841 actgccaaag actcctgaaa tgtaattcgc tttaaagcat gtactggttt gcagcgacca
     6901 ccagctttct gaaacattgg ctttaacaac tacttcgttt cgatcttcgt cttgttatta
     6961 ttaatatgtg tctatcatag agcgcaactt tttctttgtc aacagaaaaa ggatattttt
     7021 tttaaattcc tcattttttc ttttttgaat ccgctctaat tccgaacatt ttattttcaa
     7081 ttattgttaa aagaaataac tttttctgta ttttttctgc aatttatcga gaagtcactt
     7141 tactttgcct cttattcttt cttcgttaca ataaggaatg ggacaagtaa aaaaatgaaa
     7201 aagcaaggga cgaggtatat ggaaaaaaag caaaaaatta ttttaggagc cacttctgct
     7261 ttaactatcg ttattttaat tctaagtttg ttttttgtca tccgatcatc tacaaaaaaa
     7321 gaaccaatca ttcctgaaaa aaaaataaca gaaaaagcaa aagaaccgac agatgataag
     7381 caacaactag ttactcaagc aaaaaatctg gctcaaagct acgattatga ccaagcgatt
     7441 gcgttattgg aaaaagatag taagaacgga tctactgaaa cacaacagct tcttcaaaca
     7501 ctaaaaaagg agaaagaaca actgatcgac tggtctgatc ctactcagat ctctcatgtc
     7561 tttttccaca gcttgatcgt ggacccgcaa aaagccttcc actctcaaca ggcacaagga
     7621 tacaaagatt atatggtgac tgttgaagaa ttcaaccgtt cgatcgaaca actttatcaa
     7681 aatgattttg ttttagttaa tttgaatgat ttgatccaaa aagacgaaca aggaaatctt
     7741 tcctttaacg ggcttgcgct acctgaagga aaaaaaccat tggttctttc acaagatgat
     7801 gtcagctatt atgaatatat ggataattcc ggttttccta gccgattggt cgtatcaaat
     7861 aacaatgaaa tcaaaaatgt ctataaagag aaagataaag aagaaatcgg tgactttgac
     7921 atggttcctc tgatcgatgc ctttgtcaag aaacatcctg atttttctta tcgaggcgca
     7981 aaaggtacct tggccctgac aggttacaac ggagttttag gttatcgaac atcaaaatct
     8041 caatatggag acaatgaaaa aacaaaaaaa gagattaaag aagctaaaaa agtggcggaa
     8101 cagttgaaga aagacggctg gagctttgct tcccatacat ggggtcactt gaatatgact
     8161 caagcttcac tagaagatgt aaaaaaagac aatgaattgt ggcagcaaga agttgcacct
     8221 atcctaggaa aaacaaatat tctgatttat ccatttggtg cagacatcag cgactggcag
     8281 ccttattcag cagaaaatca aaaatttgct tacttgaaga gtcaaggttt cgatattttc
     8341 tgtaatgtcg atgcttctac accagcttgg ggacaattag gtacggattt ctatcgaaat
     8401 gctcggatca atatcgatgg cattcgtttt caatctgatt tagacggaaa aaatcctatt
     8461 cttgatccat tcatcaatgt ccatgatgtc tatgacaaag aagcacgcga atctgcttga
     8521 ttttacgtca tttatgaacc aaaaaagccg aactgacatt ttatcgtcag tttcggcttt
     8581 tttatgcttt atttcttctt cggtgcgatt cccttgatca ggacttctgt ccattctgct
     8641 gtatatggaa gcagttttgc gtatatctcc ggcttagaaa ttccttctac cattgcttga
     8701 aaatagagga tcaagaactc atccgaatat ttcaaatcca cttttccttc tttccgccct
     8761 cgatggaaaa gatcaagcat gatactgaaa ctttcttgcg tatacgcatc catcgcgtca
     8821 gaaaattctt ttttttcttt ttttgtatag tatgtcatca aatcgatata aaattgtttg
     8881 ttcactcgat tgagataacg gattttgttt tcactcatgg caatcagtgt ttcttcaaat
     8941 ggaagatttt ccgcaatcaa cgctttcgct tcttgcccta aatcattcat aaatgcaaaa
     9001 aatacttcat aaatcagccc ttccttgctg ccaaaatatt taaaaatcgt cgctttactt
     9061 acctgagcgt tctcagctac cttatccatt gtcactccag cggttcctat gtctgtgttc
     9121 atcaagtcaa aagctgcttg taaaatctct ttctttttct cttgtgctct cttttcaaaa
     9181 ccgttcattt gtagagcctc ccgtaatttt aaacttttat aatatatata gttcaaattt
     9241 attctgaggt ttattataac tatctattga gaaagtatca agctagcaat tccttgttta
     9301 tgaattcatt gacagaaatt tataaaaaga atattatgta ctaaaataat aaaaaaagtt
     9361 ttataaaaag gtataaaacc tttttattaa actatttaat cttgtttagt atatattttt
     9421 agaaaaagga gtggggtttt tatggcagaa atcgtcaaag tcacacattt gaaaaagagc
     9481 tttggtcgtt tcgaagcttt aaaagatgtc tctttcaccg tacattcagg tgaagtcgtt
     9541 ggatttatcg gaccaaatgg ttctggaaaa tccacgacga ttcggacact tttagggatt
     9601 ataaaaaaag acggcggaac ggcaacgatt tttgggcaag atgtatggga agatagttta
     9661 tctatccatg aacgtctttc ttatgttcca ggcgatatct ctttgtgggg aaatttgact
     9721 ggaggagcga tcatcgatct cttcatgaag cttcatggaa aagggagtgc tcaaaaaaaa
     9781 gatgaactga ttcaacgttt ctctcttgat cctaagaaaa aagcaaaaaa ctattcaaaa
     9841 ggaaatcgcc aaaaagtggg cttgattgct gctttggctg ttgattcgga tctctattta
     9901 tttgatgagc ctacttctgg tttagatcct ttgatggaaa cgattttcca agaagaagtt
     9961 gaaaaattga aagaacaggg caaatccatc ctactttctt ctcatattct cagtgaagtc
    10021 gagcgactag cggataaagt cgtgatcata cgcgaaggaa cactcgatga agaaggaaca
    10081 ctcgatgaat tgcgtcattt gactcgttcg accatcacta tagaaacaga agcagagaat
    10141 agtcacttag cacaattgaa cggtgtccat gactttgtgc aaaaaggtca cctcgctcaa
    10201 tttgctgctg ataacgaagc tttcgatgtg attttagctg aagcgtccaa attaggtgtg
    10261 aaaaaatttg aatctattcc accgactctt gaggatttat tcatgagaca ttatgaagga
    10321 tgaggaggaa gcgaaatgac tgataaattt tcacgctggt ccaccctttt ttctcaaaac
    10381 cttagccgtg actggaaaaa gatcctgata tggctagtcg gtgtcactgc tttttctggt
    10441 ggttttgtcc ctgcgtttga agaattgact tccggacaag gattagctgg attatacgaa
    10501 accttgcaaa acccggcaat gattgcaatg gtcggaccaa ctccagcttc gaatgctgct
    10561 gagtatactt taggagcgat gtatgcaaat gaaatgttgc ttttttgcag tttgtttgct
    10621 gctgtgatct ctgttttaca cgtggtgagc caaacgagaa aaaaagaaga acttggtctg
    10681 attgaactta ttcgttcctt tcgagtcgga cgtcaagcaa actctttagc tgtcatcgct
    10741 gaaagtattc tgatcaattt gcttttagca atatcgatca gctgtacgat gatttttttc
    10801 caagcggatt cgatcactgc agaaggtgct tggctttttg ggctatctgt aggtagtatg
    10861 gggattttgg ggagtgccgt tgcactgttt gctgcacaac tgatgccaag ttcagccagt
    10921 tcgaatggtc tgtctttagc gtttttaggt ggactttacc ttctacgagc aataacagat
    10981 gtagctgatt cctccctttc gatgtggaat cctttaggct ggtcttattt gacctatcca
    11041 tttacaacta acaactggat tcctttgctt tatttgtttt tgttcagtct aatcttgata
    11101 atcagttcat ttgttttaga ggaacatcga gatttgaaca ccggctatat ccccgaacgt
    11161 gaaggaaaac cgtatgctaa acgttctctt ttatccttgc gtggtttatt attctatcta
    11221 aataaaggga tgacaatcag ttggcttatc acttttggtt tgatgggggc ggcatacggc
    11281 tctatctacg ggaatatgca acagttttta gaaagtaacg acttaatgaa acagatgttt
    11341 atccaatctg gcgtctcaat tgaaaaaaac tttacaagca cgatcatggt agtcttgatt
    11401 tgtctagctg ctattttacc aattgctagc atcaatcgtt tatttacaga agaaacccac
    11461 ggacgtatga atcagctgtt cgcaacaaaa atttctagga accaacttta ttggaccaat
    11521 atgttactag ctattctatt tgctatattg gcaatcctga ttagttctgg tgcactaggg
    11581 ctttctgctt tggcttcgat gaaggatgcg aaagacatgg atctattgat gtttcttaaa
    11641 gccgggttca atttcctgcc tgccgtttta gtgtttatcg gaattagtgg ctttctattc
    11701 ggatggcttc ctcgaatcgg taaacttgct tatatctact tagcttactc ctttgcactc
    11761 aattactttg gcggaatttt ggatttacca gaatggtttt ccaaaacagc tgtccctagc
    11821 tgggttccac ggatgccaaa cgattctttt gatctttccg tgttccttac gttatcatgt
    11881 atcagccttg cactgttcgt ccttggttct attggttata ggcgaagaga cttactagaa
    11941 ggataataaa aaagcatgta caatttcatg ctagcctcca aatctgggtc aaaaatccaa
    12001 catttggagg tcattttttt atttacaagt cttctaactg ctctttatca atgatccaga
    12061 cttctcgatt ctttcttttt acataaccat tctcctctaa taatttaaat tttctagata
    12121 aagtttcggg ggtcgtaccg ataaatgcag caagttcttt cattttcatt ggcaggaaaa
    12181 agtgatcctt ccctgtcgct ttagctaagt caagcagata gacagcgact cgttcttcta
    12241 ctttttccat catcaaaaaa gttgtctgct gctgtacttt tgttaatttc tcaacgttga
    12301 ttgctaaaag tttcagacta agggcgggat aatgcagtaa gagttccgag aaatcttttt
    12361 gtctcaatat gcaaatttcc gttttttcta gtgcttcgcc aaataaagac tcatttggaa
    12421 cgcctagcaa ctggctctct ccctcatatc cgcccggctc tattactcgt aaaagctgtt
    12481 cctttccgct agcagataat tgatacactt tcatactgcc ggaggccacg atcactaatt
    12541 gaggttctcc attcggcgca agaatctgtt ctcctttttc cacatagtga tgtttgacaa
    12601 gtgcgtgtac tttttcttga tcttgctgta ctaagtgatt gaacaaagga acaaatgaaa
    12661 cacataaatg atcatgactc ataatctctc ctccttctaa acagctattt ctaataaaga
    12721 aacataactt cccttattcc aactgataat tttcttttat catagcataa acgtcaagcg
    12781 aaccagatac cagcaaatag agtggatttc tttttgtccc ttgctttatt ttccttcttt
    12841 tgagacctta agtaattgat tcctatcaat tttttaaata tttacttttt gaataatcaa
    12901 aaacaaacct tcactcgcaa gccgagagta aggtttgttt ttcgcattgc ttatttcgtg
    12961 ttgtctattg aaatttttcc gcacctagct tttgatatag tggtgctagt tcttgtaagg
    13021 tttcagcggt tatttgctca acgtgttcga tttcttgcgg atagaagaat agtttaccca
    13081 tttgaaaggt tcggtctctc atcgcttttt tcaactcttc ttgtttcttt gtatcggaca
    13141 aatagtcaga caaagctaag tggtcgtcaa gttcatgttc tggttgcggc catatgtaat
    13201 aatccttgat atcgactgtt ttgctccact ctttcagtat cgcaagcaac tggttatacg
    13261 ctgcaatgct accatatcgt tcttcgcttt tataatgttg gtacatcaaa tagatttggt
    13321 attgtttttg attcaacaaa actgctagac aggcattctc gtcttgacga gattcgcttc
    13381 ggtacgcgct ccaaaaatga ctgcgtaaat tccagccatt cgtccagctt tcgattttag
    13441 gtttgctcat gccgtacata tcaggcaaaa gtgcagctgt ctggagctga atctctttcc
    13501 atttttgcca gtgttcttta tattctttct tgatttgttc aatcttatct gttggatggc
    13561 tctctttgag ctgtttgaat gcgtagattg gtcgatcaaa caactgataa tctgattttc
    13621 caagttccat tgtttcgcct ctttccgtta tcttttgtat tctacctgaa ttttgcgata
    13681 tggacaaata gaggttgtga aaaagctgtt ctgcatcaag tcataagaac agccaaacaa
    13741 aaaactgcga tgagcatcac cgcagtttta ttgaacttaa ggttgattga tcacatctaa
    13801 aagcgttgaa aataaaatgg cactagaagc agctcctggg tcgatatgtc cgattgcacg
    13861 ctctcctaga taggaagctc gtcctttttt agctaccaag actttggtgt gttcttttgc
    13921 ctggtcaatg atttcttttg ttaaattccc tgccttcaat gcctctgtga ctggcagcca
    13981 aacatctaac atcgttttat cgtcagcttc tgcctttcct cggctttgaa tacccgctgt
    14041 tccctgctcg atcacttcgc ctaatttttc ttgagaatca atagaatcga cctcttttgt
    14101 cgctttcatc atgttcatga atgcagatcc gtataacgga ccagaagccc caccgacttt
    14161 cgatatcatc gccatagaga atactttgaa tgtatcgctg attgtttcag gatgatcggc
    14221 ttgaaaagct tcttcataag ctgaaacccc tcttcccatg ttatttccat ggtctccatc
    14281 gccaatcggg gtatctagat cactgagata ttgtttgttc tgattgattg cctctgcaaa
    14341 ttgcgtgagc cattcttgga tttcttgaac ggttagtttc atattatcac ccttttatct
    14401 tgagattttt taccatgaaa tcgtctgtac attgctttct aaagaatctt tccattgtgt
    14461 ctccgtcaag tcgatcagtg ttagagaaag accttgcata tctagtgagg tcataaaatt
    14521 accgactttt cggaaaacta cattgacgcc tctttcttcc aacagagcta aaacatcatt
    14581 catgaacacg aactgttcca tcaaaggcgt cccgcccatt ccgttgacta gtacacctgc
    14641 ttcttttggt aaattcgagt aatcatctaa aatcttagta acaagttcct ttgccagtac
    14701 tttagaaggc tgcatctttt ctcgacgata gcctggctca ccgtggatac caacaccata
    14761 ctcgatctca tcttctccta gttcgaatcc tggtttccct acttctggta cagttgctgc
    14821 tcgaagcgct agaccgatcg tcttagttgc ctgtacgacc ttttctccca gttctttcaa
    14881 ctcagctagg gaagcaccgt ttcttgctgc atcgcccacg attttgtgta caaggacagt
    14941 acctgcaact ccgcgttttc cagcagtata cgtactattt tcaacggcga tatcatcatc
    15001 tacgatcaca ctttctactt caatatcgtc catagcagct aattcctttg ccatatcgaa
    15061 gttcaatgca tcccctgtat aattcttaac gatcagcaaa actccttttc cactatcggc
    15121 ttccttaata gccgtctgaa tctgatctgg agttggagaa gtaaacacat caccaagcac
    15181 cgctgcactt aacatccctt cccctacaaa cccggcatgg gatggttcat gtccgcttcc
    15241 tccaccagaa accaaaccaa cttgttccgc tttctgattc ttggctacaa cacgggaaga
    15301 ttctacacga tgaacaagtt ctggatagct ttttactaat ccttccagca tttcttcgac
    15361 aatattgctt ggatcattca tgattttttt caatttattc ccatcctttc tttccggcat
    15421 tttgtgcttc tgttaagatt tgctgagtat catctgttat accggcagtg atggctgctg
    15481 caaaagctcc ttccactaaa ggcgcatcca ccagatgata acgttgctgc tgctcttctt
    15541 ccaacatgtc ttttgccagt tccgagttca ataccgcgct accgatatcc gcaaaaacaa
    15601 aataactagc tgcatcgctt gattcattga ctgcttctac gattttcatc gggtctgatc
    15661 cgatctcgcc atttattccg ccgagagaaa aaatttgcac ctcttcggat ttttgcatct
    15721 gctcaatcat ttctttaata ccatctgtta ctttttgact atgagaaata agcaaaatac
    15781 tttttttcac aagaatcttc ctttctttta catagttgct aacgattggt ttcgctttca
    15841 ttaatgaaca attcaagtat ataataaatt tctaattttg ggaaaatatg tgtagtgctt
    15901 cttgaagttt gttatacttt aattaaaaga gaggagtgat cgaatgatta caacaacaac
    15961 gaacagtgta gagggaaaag ccgtagtagc ttataaaggg atcgtttttg gtgaggtcat
    16021 tactgggatc catgcattta aagacttgga ggcggggttg cgaaatatct ttggcggccg
    16081 ctcaaaaagc tatgaaaacg aactaatggg tgcaagagaa gaagcacttg ccgaaatggc
    16141 cgaacgtgca aaagcattag gagctgatgc gatcattggc gtaaaaatgg actatgaagt
    16201 attaggcagc gacaatggca tgctgatggt cacatgtagt ggaacagctg tctccacgag
    16261 ataagtaggg gacatctgtt ttaataacta aagagagatg ggacatgtag tggcactcaa
    16321 gaattagatt tttcagtcta acttcgaggt actctacctt cccatcctct cttttttatt
    16381 tctttttgcg gatgattccg taagctgctg cgactaacac acccgcccct gctaaggaat
    16441 aactgacaga agctgttttt tcatttgttt ttggcaaagt ctgacttgtt gatttggatg
    16501 gctctgtcgt ttgctgaact gtttctgtcg tgcttccaga ggtcactgat ttttctcctg
    16561 ccgaatgcaa aatatctttt attcgttgga aactagctgc taagtcagct ttttttgctt
    16621 caaaatcatt agcaactgtt tgtgcttcgc tgatctttcc gtggattgct tgactggccg
    16681 ctgtgatatc cgcttgagtt tgacttagct ttccagaagc tgtttgagca acctgattta
    16741 attgctgatt gaattctttt gcttgttgga tcttcccgtc aagatctgtt tggacagctt
    16801 ccgcttttgc tttcgcttcg gcaagctttt tctcaagttg tgcacggtca tttcccactt
    16861 tatttttaag atcagctaaa tcttgatcga ttgctgcttg gtcttctttc aatttgtttt
    16921 ttgcagcttc taatgcttct tcgagttctt ttcttttatt ttccaagtct tgcaaatgat
    16981 cgatttggtc agaagaggta gaactattta ttgatgtatc ttctgaagat gaaatcgttt
    17041 ctcctgaatt atctgtcggt acattggaag tcatttctgt ttccgaggca ccgttttcag
    17101 caccagaaga gcttatggtt gttgaaggtt ctgtttgagc aggttcagaa gtttccgcaa
    17161 aagctgtctg tcccaataag aaaatactgg aaacagcaat tggccagatt aacggcttca
    17221 ttcttttttt catcactttt cccatcctta ctacttttta actaatttct tattataagc
    17281 aaaaatgttt ggaagaacca taaacacaac aggctgtttg tctaaaaaac ggtgcatctt
    17341 ttattttttt gtacgttccg ggcttttcca tgtcccgctt ccataaccta aaatcgtttt
    17401 gactgctgga atgaaagtcg tcacgatcgt tatcgcgttc actatccaga acaaaagcat
    17461 atatagtggt gcgaaaagaa ggtatttcaa ttttcttcgt cgatcatcta caatcagcga
    17521 agctagcaac tggaaaaatc ctgcgaccat ttcaaagcag atgaacacaa aactgaatgt
    17581 aaaagtaata taaatctgtt cgtagtttcc ttgatataca taatgcccga ttaatccagc
    17641 aaaaagaact acggaaatac aaaagaatat tgaccagaca atactcaatg tttgatcaat
    17701 gaagatgatc gttcttccaa tatgtttaaa aggatggagc atcacttttt tgaaattcgt
    17761 cagccagact tctgttccac cttttgccca acgttttctg tgtcgatata gcatcttcaa
    17821 cgtcacaggt acttccatga aaaagataat ctcaggagca aaaacagata accagtcatt
    17881 taactgatga tcccaagcaa tactgatgtc ttctgtcgct cgatcttgtc tgaatccgcc
    17941 cacatcgatc aaggcttctt ttcgatacat cgtatttgct ccactgtacg cataaagacc
    18001 accgaaaaca gctgactgtg ttcgtttaat gatgcccacg atacttgaga attcaaccgt
    18061 ttgagatttt gcaatcaatt tggtacgatt ttggacatcc atatttgcag tgaccgcagc
    18121 aatatgtctt gcaccagggc gaatgaaata attcacatac ctaatcagtg catctggctc
    18181 cggtaccgtg tctgcatcat tgcttaaaat caatttccct tttgcaaagg caagtccgat
    18241 attaaacgcg tgggcttttc ctttattttt ttcgatccga accacacgaa gattagcgta
    18301 ttttttcatc agtctagcta atatttctgg tgtttggtcc gttgaaccat cgtctgtcac
    18361 taatacctca tagttgtgat aattcaattt cgtcatcaaa tactcgattg tatattcgat
    18421 cacaatttct tcattatggg ctggcaccat gatcgtgatg aacggttcga cactcaaggg
    18481 aacatctacc cattcttttt gcttatgttt gtataaaaac acataacacc agacaccaat
    18541 aaaccataca aatccgccta aaatcggata agaaacgaga aaaaaataca taatagacaa
    18601 acaagtatct aagaataaat tacctgtatg ggtgattgag atcatttcag ttccacccca
    18661 ttttctttat acaaatctgc aatgaatgtc gtatctagat ttttctcttc ggagacagaa
    18721 taaaaacgga ccgtttctct ctcttctttt gttccaaaac gttccgtata cacttcttca
    18781 agtaattctt gtcttttttt caatttttca tcttcatatt caaaagattt atttactttt
    18841 ttgtatagat ttcgattgtt ccacctagtc aatacaaatg aggtaatcag gaaactgaaa
    18901 aaaatcaata caaaaaagcc gattaagaaa tacagcattt tcttttctga taaaaaagcg
    18961 tacaaggaaa aatccttggc tctttctggt ctcgttaatg ggaaaaagac ccatataaaa
    19021 ggaagaacaa cgatcatcca tcctaaaaga gccactaacg tttgccaaat ctttaaccag
    19081 taattacctt ttgaaaaata cttatctttc accaaaattg atgcaacttc ttctcttgtt
    19141 acttttttca tatcctcacc tcacgttttt ttgttacgac gtaggagttt accatacatt
    19201 tcatttcttt tcacataaag tgttcctaaa tttttcctaa gaaaaagaac aaaacatttc
    19261 tcatcagcaa atgaaaaata ttttgttctt tttatcagtt gttcttttta ttttttatct
    19321 cttaattatg ttgctctttc caatacgaca atgcttttca ttcctctaga tatcgccgtg
    19381 tacatttgtc tgcgtcttct ttgctcatct ccatcgtttt caaatggata taagattaca
    19441 tgatcaaatt ccagtccttt tgctagactc aaaggaatga tttggcagtt ttctaatcca
    19501 tatgaatttt ttttaatcga ttcttgtagc gtttgggttt cctcttctgt ttgggtgata
    19561 actgccgctt tttctccttt tagagaaacc aaaatctcag ctagtatttt caacaattct
    19621 tcagaggatc gaaaagagcg gtattcgggt tcttttcctt gcggtcggat cgatacgatg
    19681 tcgatcttct cttgatccac agcataggtt ttgaaaagct ctgtgattgc tccgctagaa
    19741 cggtaactat ttctaagatc ataccgatgg atcggcagat ggtagtcgtc gaaacaacgc
    19801 ataatatcag caaaagtagt ggaagaatta aagattgcct gattctcgtc acctactaaa
    19861 gtaaagtgag tttttggaaa taattcgatc aatagaccta attgtgccag ggtataatct
    19921 tgtacttcat caatcaatag atagcgaaat gctggtacat ttaccttttc aacaagtaaa
    19981 tgacgaatag ctaatataat gactgcttca tcaacagtac gtgtgggttg ccaagcataa
    20041 gctgagccat atcgtttttc ataaattctt tcaaacaact gatgctcatc cacccatgcc
    20101 atttcttcga tttgtctggt tatttttcga tatttttttt gtaaaagttt ccttgcataa
    20161 gctacaatac tttgttccga atcatcagaa atcaatttac cgaataattc caactgccta
    20221 tcttctgtca acgagagtac ctgattctgc acagcaggac tttttgcttg tttcaaaaga
    20281 tgattcttcc attcgctcat cagtgccttt ttcgttgctt gaagcctatc gatcaattta
    20341 ggatgagcag gaactttctc atatattttt tcgatcgttt ttttagaaag gactgttttt
    20401 ccatttttag taagtccacg gataaaattc ggatgatcta aaaacaaagg atctgattgt
    20461 tttagattat cgataaactt tttgctacgc aaacgttctg tctgctccga tacattttct
    20521 cccgtgatac gtttgaaata agcctcttca ccttctattt cctctgctga aagctgtgaa
    20581 accagctgta tgatggttag attcagtgga tttctttcac ctaatgatgg taggacattc
    20641 gaaatatagt cgataaaccg atgattaggt gatagaatca gcaagtcatc ggatgtcatc
    20701 gtatctcgat ataaatagag cagatacgca atacgctgca tgatagcaga ggttttacca
    20761 cttcctgcta cgccatttac caagatattt tgacttttca catcccgaat gattgtgttt
    20821 tgttccgatt ggatcgtagc agtgatagcc ttcatttcat tggtctcatc ttggcctaag
    20881 acttctaata atacgtcatc ttgaatagct acagacgtat caaaaaactt gaccaaacga
    20941 tctctttcca aaagaaattg tcgtctttct ttaataaccg tatcgatttt attttgacga
    21001 accgtataag aagatggacc aatcatgtta ttgtaaaaaa gttcggcaat tggtgaacgc
    21061 caatcataaa caagattttc atctgcatca tctgtgaaat ttgctgtacc gatataaaag
    21121 gattcttttg gctcattatc cagaaagtct acaacgactt ttccaaagta gggacttttc
    21181 aataaacgtt cgatctttgc tagctgattt tctgcgtttt tctgtttgat attcatctga
    21241 tcgatttctc tatttttcat ttcaatcatc gaaaaagtat ccaggttatc taagtaactg
    21301 tcaaaattca atcgaagctc gccagccatt tctttcaacg actggtttcc ttctattttt
    21361 gccgtatcca tcgattcccg cagttcgttt tttttatcaa ttagcttttg atacacgttc
    21421 ttcagatatg cttcttctaa ctgtttttgt gtgttgacca tacacattct cctctttttt
    21481 taaagtggtg gaaccgatta gtttacctct tttaagagtc gaatgcaagc tttttaacga
    21541 gtatcatttg ttaggatata tcagttcttc aggtcggaca gtttgatata aagaaaatgc
    21601 accatcaagg ttttttacgt ggtagccaga ctgcttcaag attctttccg ctagatagct
    21661 acgtaatccg ctatgacagc tgacgatata ttcttgttgg ctgtctaatt catttaatcg
    21721 gtcccgaagt tcattcaaag ggatatgttt ggcttccttg aatttgccct tttccaattc
    21781 ttctgctgtt cgcacatcta ataaaatttt tccttttgct agttctgtcg gcaattcatg
    21841 ccattgtacg gtttcactaa gcccttctgc aatgttcatt gctgcatatc ctagcatgtt
    21901 tactggatct ttggctgagc caaatggcgg tgcatacgtc aattctaatt ccggtaaatc
    21961 gaagatcgtc aaatgccctt tgattgctgt tgctaaaata tcgatccgtt tatccacacc
    22021 ttttgcccca acaccttgtg caccataaat ctcgccagtc tctggatgga agatcaactt
    22081 cagtaaaata tctgttgctt ctggataata gcttgcatga tcttttcctg atacatgaat
    22141 gacttcaaaa gacagttcgt tttctttggc tgttctttca cttaaaccgg tggatgcggc
    22201 agtcattcca aacgttcgta taattgctgt tccaataccg ccttgatttc ttcgagaaat
    22261 tccggaaatc gtgtccgcaa cttgtctacc ttgacgattg gctggtgaag caagagaaat
    22321 aagtgcatct tttccagtga tttgctgttt tacaacgata gcatccccca ccgcataaat
    22381 atcaggaata ttcgtttgat aacgttcgtc tactaggata cccccgcgta tgcctaattc
    22441 gattccagcg gtcactgcta gctggttatc aggacgaaca ccaatggata aaataactaa
    22501 atcagcaggg atggtacgcc catcatccag tcgcaatcgt ttcccgtggt cttcaaatcc
    22561 agcgacagca tgagaagtaa tcacttctac tccttgatga gacaattctt tttctataaa
    22621 agctgccatt tcttcatcca gtgttggaag aatatgtggt gcttgttcga tcaccatgac
    22681 ttctaaacct cttcttttta ggttttctgc catttccaat ccgatgaatc ctgcaccaac
    22741 gatcacggca cgctttggct gtttttctaa tgcatgcatc actttatcga tatctggtac
    22801 atttctaata gaaaaaacat tgtcggcttc tgttatccct ggaatcgatg gaacaactgg
    22861 ttttgcacca ggagataaaa ccaatgcatc gtactgttca atgtgttttt gaccctcatg
    22921 tacgacttct accgttttgt tttcgggaaa gatggctgtc acttcatgat ttggacgcac
    22981 atctaaacaa aaacgagcgg ataatgattc tggcgtttgg acaagaagat tttcccgttc
    23041 actgatttct cccgaaagat aataaggcaa gccgcaattt gcaaaagaaa catacggtcc
    23101 tttttcaaaa acaacgattt ctgcatcttc cattaatcgg cgaagccgtg tagcagcaga
    23161 cattccacct gctacacctc cgacaataac gattttcatc ttatttccct cctactgttc
    23221 gatcaaacca ttgattcatg ccaccacgta cattcactac atcataacca gatttcttta
    23281 attctttagc tgcttgttta ctcctcatcc ctgattgaca aatcacatag acggtctttt
    23341 ctttgtctcc atcatatctg tttatacttt gtaatggaac atttttagct ccttttatat
    23401 gcccgccccg gtattctgca ggtgttctaa catcaagtaa cgctggattt tccaaaagct
    23461 tttcctttaa ttctgggact gttatcgatt ttattgattg aaatagcaaa ttcattttct
    23521 gcacctcatt tacattttta taaatacctc atggggtata ttaaacagga gctttattaa
    23581 tatgtcaacc agaatgactc ttcatttttt tcactacttt ttatatttgc ataaaatacc
    23641 gataaggggt attatctaat tataaaaata gaggagaatg tgttatggag attgataata
    23701 aaaatatcct gaaccgtttg aaacgtacag agggacaaat tcgtggtatc caaaaaatga
    23761 tcgaagacga aaaagaatgt atggatgtca tcactcaatt aagcgctgtt cgttctagta
    23821 ttgatcgcgt aatgggcatg atcgttgcag ataatctgaa aaattgcttt gagaaacctg
    23881 atagtaatcc agaagaacaa gcggctaaac tagaacaagc gatcaagatg attattaaaa
    23941 agtaaaggaa tgatttcaat gaaagtcgtt ttccatattg atgaattaga aaaatggtca
    24001 gaaacaggga aaaacgtaaa aaacctgata aaagcttctc cagaaacgac gattgtcgta
    24061 tctgtaaatg gcatcgcgat taccggttat ctagactctg ccaatgcaga attcttagat
    24121 ttgcaaggag tcgtttttca cgcttgcgcc aatgctatgc gtgctaatca tatttcagaa
    24181 agttctttac ctgaacaagt aatcgttgta ccagcaggtg tccttgattt agttgaactg
    24241 caatcccaag gttatgctta tatcaagcct tagtcagtag aggttgcgac agaagtgatc
    24301 agcttcaaga aatttcggct tatttttcga agaagctact tctggaaaac cgtgaatcaa
    24361 aggttgtgaa aacgctgtcc tgcatcaagt aataagaaca gccaaacaaa aatagcttct
    24421 catatttttc gtttggttgg gcttattacc gcagatgcaa gcttttgaac accgtttaag
    24481 gaagaggttg tgaaatcagc ggtttgacct aagtattaga gaaaaaaacg ggaaaatagc
    24541 tcctcatatt ttgccgtttt ttgagctaat accgaaggtc agctgattga acaccgttta
    24601 aggaagagat tgtgaaaaag tcgcttagtt tcgagtatta agaaaaattt tgtgaaaatg
    24661 gatttctaca tttttgcata aatttggctt aataccgaga aactggcttt tgaataccgt
    24721 ttaaggaaga ggttgtaaaa tcagcggttt gacctgagta ttagagaaac aaacggaaaa
    24781 atagctgctc atattttgcc gttttttgag ctaataccga aggtcagctg attgaacacc
    24841 gtttaccaag aggttgtgag cctaccattt aactccgaat cacaagaaat aatttcaaaa
    24901 acaacttctc ctgtttttgg ttcggttggc ttattatcga gaagtagcta ctgggagtct
    24961 atttatcaaa aaaaggaatg cgacataggt cacacccctt ttttattttc tttgaaacat
    25021 ctttcggtac tcgacagcat acaagacaaa agattgtaaa agaccgtaag tgatgacggc
    25081 aaaaatgact ctcacccaca gcgttggtaa ttctgggaaa agcagcaaaa ggatcatgcc
    25141 aacatagatg acagcagtcg ctactttgcc ataccacttc gctccactta atttgatatt
    25201 tttagatagc ccgattaatc cagctacaaa cataaagcct tcttttatca agaatagacc
    25261 aaacaacagc caaagccacg gtcgatacca tgccatagac aaaatcagaa aaagttgtgt
    25321 caatttatct gcaaacggat caagcacctt ccctaagtct gttacctgat tatatctccg
    25381 agcaatgacc ccgtctagat aatcagacaa acctgagaca acaatgaccg ctcctgctat
    25441 ataaaatgac tgtctcagca caaaataaag ataaatcggc agcaaaaaaa tacggaatat
    25501 cgataaaaga ttcggaatcg tttgtatttc tttacgccag tctgtgctta atttcatttt
    25561 atcgccctac ctcctcagca ctcttttctt tttattttag cttacacggg gaataaaacc
    25621 aatgatttca ctgtttttat ttttctttac agacactgat attatgagct aatttgagat
    25681 aatcacttgc tgttttcatc gtttactctt ctttcttcct gtcgtttgcg catttctttt
    25741 actagtactt tatgagcttt ttttgatcct cgctctaggt cacgctgccg tttacgtgtt
    25801 ttataatcga taaacagact gtctaaatcg taacctgtcg ggtacagatc ttctgctgaa
    25861 cgcaccagac gaacacgctg acgaggcacg tggattattt ttttgtctaa atatacatca
    25921 atcgtatctt cacctatatc ttcataaact aacgcttctt tttggtattc attgacaaat
    25981 atccgatcac cttttgcaaa gagctgacgt tcttttttat tctccttcct atttgtaact
    26041 gctgtcttag gaagaaattc ttttttctgt gtccgatagg ctttttccgc caagtaacgc
    26101 tctgcttgat ggatcaattt catcgacata tccattttat gagcaatcca caaagcttgg
    26161 ctttctcctg tttcttccaa cccgcaactg atatttagga cgaagtgctt cccgatcgaa
    26221 agccatagca gccggcacaa aatcttcatg atctccggcg aatttcttga tttctccata
    26281 atgggtcgtg gcaatgatca atgccccttg ctcatacata gattccatga ttgcgatcgc
    26341 tagtgcagcc ccttcatttg gctctgttcc actgccaatc tcatctaaaa gtaccaacgt
    26401 attccttttt atctttttca aaatagcagc gatgttttgc atatgaccag aaaatgtact
    26461 caacgcattt tctaaatttt ggtggtcacc gacatcgacg aaaatctcat caaagacagc
    26521 aagctctgtc ccttcttttg ccggaacttg cataccgaac atcgccatca aagtcaataa
    26581 accgactgtc ttcaacacga ctgttttgcc tccggcattt gctccggtga taatcaagcc
    26641 tcgatagtct ttaccgattt caacatccaa tggtaccgca tgctcaggta aaaatggatg
    26701 tctgccttgc ttgataatga tatgttccga tttattgatt ctaggtgtgc ttccattgat
    26761 ttctcggcta aattttgccc gagcaaagat gatatctaac accgtgatcg tttcgatcaa
    26821 taaatcgatc acttcttcgt tttctgcgat agcaccagtc aatgccgcca ggacttgata
    26881 ttcttcactg atttcttcag cttttaacaa ctgatagtgt tcattcaatt tagaaatcac
    26941 agttggttca ataaaaaccg tcgttctttt atttgattca tcgataatcg ttccatctat
    27001 tttattttta tagctggctt tgataggaat cgtatagtat tcgccttttt gaacaatcat
    27061 tgcttcttgg atcatttctt tgtttttcgg atgacgcaag aatttcagta attttgactg
    27121 gatttctttt tcgattagtt gtaattgttt gcgtacttta cgcaaattac gtgacgcgtc
    27181 gtcactgact ttattatttt ttattttctg gtcaatcaac tcttctacat ttatcaaatc
    27241 aggaagatgt ttgctataag caaacaacaa gggtgtctgg tattgattct tatcaaaaaa
    27301 ctttgtgatc atccgactgc ttctaagaaa atccgcatat tcgatcaaat cggttggctg
    27361 cagaatcaac ccttttttga cttgttctgt cagtgcatcg atcctcggca accccataaa
    27421 tggaacatgc tgactgcttt ctaagatcaa gcgtgcttct cttgtttctt cttgacgatc
    27481 caagacagtt tgtaggtttg tcgagaccgt catatcgctg attcgttttt tgctatagtt
    27541 tccaattgct cttgcttgga tttccttttt gatccgatca aattgtaatt gactaatcat
    27601 ttcgttgtcc atattctctc cttttcttga agagatacct gtcccaaaat aaataagggc
    27661 ctagagataa ataaaaggat agaacacagc ttaaaaaagt catgtcctat ccttattaga
    27721 atacaaagat attgttttcc tgacaggtac cgtttcataa gcacaccaaa taaactttgt
    27781 ttattggcta ttcgacttac tgattagata ccagctacac tcacaaaaca taccccattc
    27841 ttctaggtct tatttatttt ccacttaact atagcaagac acattttggt tgtcaaactt
    27901 tagtatgttt tatagattta caccattaat gaatagacac ctaccgcgat aattgctccg
    27961 atcattggac ctgcgattgg tacccatgaa tatgcccaat ctgaagttcc tttattagct
    28021 attggcaata ccgcatgtgc taatcgagga ccaaagtccc gagcagggtt gattgcatat
    28081 cctgttggcc ctcctaatga aagaccgatg gctaagatca atccacctac agcgaatacg
    28141 ttcgttccag gtgcaaattc gttttgtcca aaagctagca acccaagaac taatacaaat
    28201 gtaccaatta attctgtgat cacatttgct ggataattcc gtatagcagg acctgttgca
    28261 aacgttccta aaatcgcgct ttcatctttc gttgcattcc aatgtggcaa ataagaaagc
    28321 caaacaagaa tggcccctgc aaaagctcct aaaacttgcg caatgatgaa aggaacgaca
    28381 agattccaac taattgcccc tgtcatcgcc atagctagag agactgcagg attcaaatga
    28441 gctgggccca tgaatccaga aatatagaca gccattgtta cagcgagtcc ccaaccaaat
    28501 gcgatgacaa tccagccaga agcctgtgct ttacttttgt ttaaattcac agccgcacac
    28561 acaccatctc caagcaaaac taggatcagt gtcccaataa actcccccat gatttgagtc
    28621 atatcactgt tcatttattt ctcccccttt agttcccgca gatctgattc tgcaatcaat
    28681 gcttctaaac gtttagtctg ttgcgccttc tcctcttctg tccattcaaa atatccagca
    28741 attgcatcga tcacaggttg cttgatctca tcaagctgat ctcgttcaaa caacagatga
    28801 tttgtacgac gaatgagata atcgcctggg gccaaaacca tttcttcttc taaaccataa
    28861 cgtaaccgag ctgactcagc gagactcaaa ccaggataag gtgccatttc ttttgctaat
    28921 tcaaagatac gtcgggcatt agtcccgtaa aaatcagcga tataagtagc atcttcttcc
    28981 tctaaaccgg ctgctactcc ttcttttgct aattctgtca ctgtttcttc taatttagtt
    29041 ggatcgaagt ttccacctga aatctgatat tttttagagt cgatttcttt cgtctctatt
    29101 ccgtattctt cttttaataa ttggcgtatc aatcgcaaag ctccttctgc catcttacgg
    29161 taatcggtga ttttcccacc agataaagtc agcaaaccat ctggttctct ttctaaagaa
    29221 ctacctctgg aaatcgtaga aggtgctttt tcatcacggc tgttttccaa atggttcaac
    29281 acgtcttcta cttcagcacg agaaactttg ttttccttat attcacttac tgtatcgaca
    29341 actttattga agctcttgtc tgaaatcgat ccattatctc caccattgta atcagaacca
    29401 gaattaccaa tcaacagtgg acgaagtcct gcccagcttg cttcgatatc attcaatgtg
    29461 atatttgctt ctggatagcg atgattgatc acatccaata gataatctac atcttcttgt
    29521 gtgactttcg gatccgtaaa atctccttgg taatccgtat ctgtcgtacc aaagtaagtc
    29581 ttgttttctc ttggaatagc aaaaaccatc cgcccatctt gctttcctgt atcgaagtat
    29641 gtgggttgcg gtacaggcag ttttttcgca tctacaacta aatggatccc tttagttgga
    29701 cgcattttag gagagactgg acgcgtaaaa ttcaagtttc gtactttatc tacccaagga
    29761 ccactcgtat tgatcactaa ttttgctttg atttcgatca cttcatctgt cagcaggtca
    29821 cgagctttga cgccaacgat ttgatcgcca tcatataaaa agccaaccgc tttcatttta
    29881 cttactagat aagccccatc ttcggcagcc tttttgatat tatcaatcac taaacgggca
    29941 tcattgttgc ggaaatctag atagacaccc gcgcctttta gcccttcttt tttcaaaaac
    30001 ggttctcttt ccaatacttc ttctggtgtc agcgtataat tctcatattt ggttcctgtc
    30061 acatttgcca gtttgtcata aaggtccatt gctactttga ccgagaacat attgaaggtt
    30121 gttgctcctt cgccctcata gattggcaaa agcattggat ctggttttgg gatgtgtggg
    30181 gcaatacttt gtacgactgc acgttcacca actgtgtcag ctactacttc cacatcaaat
    30241 gtcttcagat aacgaatacc gccatgaaca agtttggtcg agcgagagga agtcccttct
    30301 gcaaaatcct gcatttcgat caatcctgtt ttgattcctg atgctgctga ctggactgcc
    30361 acaccggcac cagtgattcc gccaccgatg atcaacagat ccaattcttc ttgctgcatt
    30421 ttttgaatgc tatcttgtct tgtcttgttt gaaaacatat ggatttcctc cttattcaaa
    30481 tgcttgggta gcttttactg cttttttcca accgttgtaa agtttttctc ggcgctcttc
    30541 ctccatttga acttcaaata gcttgccagc ttcataaaat tcgcggatct cgtctgtatc
    30601 tttccaataa ccgacagcta atcctgctaa aaatgctgcc cctagcgccg ttgtttccaa
    30661 gttttctgct cgttggatcg gtacattcaa gatatctgtt tggaattgca tcagatattc
    30721 attgtttgct gcaccgccat ctactttcaa tacaggaatc ttgattccag tgtcatcttg
    30781 catcgtatcg atgatatctc tcacttgata agcaatcgac tgtaaagtag ctttaatgat
    30841 atcttctttt gtcgtaccac gtgtcaagcc aaacatagcc cctcgtgctg cctgatccca
    30901 ataaggagca cctagcccaa cgaatgcagg aacaacataa acctcatctt cgcttgtaga
    30961 gcgtttcgct gcgtcttctg aatcgctagc tttttgcaac atttgaagtc catctctcag
    31021 ccattgaatc gaagaaccag ccacaaaaat acttccttct aaagcatagt aaacctttcc
    31081 atttatgccg taaccaattg tcgtcaataa attatttttg gataattgcg gtttttcacc
    31141 ggtattcatg acaataaatg aacctgtacc ataagtattc ttgaccatgc ctggttcgaa
    31201 tgccatttgt ccgaataatg cggcttgctg gtctcctgcc atccctgaaa ttggtgcttc
    31261 gcttccataa aaatgataac cttgcgtata accataaact tctgagttag aagtgacttt
    31321 tggtaacatc actcgaggaa tatttagtaa atctaaaatc tcctgatccc aatctagctg
    31381 atggatattg aacaacatcg tccgactggc attcgagtaa tcagtaacat gtgcttgtcc
    31441 atcggtcagt ttccatacta accaagaatc gatcgttcca aacatcaatt cgcctttttc
    31501 agctcgttct tgcgcgcctt ctacatgatc aagaatccag cgtatcttcg ttgctgagaa
    31561 ataggcatcg atcactaacc ctgttttttc gtggaaaaat tcttgatagc cttcattttt
    31621 taagttatct gcaattccag ctgactgtct ggattgccaa acaactgcat gatagattgg
    31681 acgtcctgta tctttttccc atattactgt tgtttcacgc tggttcgtta tgccaatccc
    31741 agcaatctga tttggtttga tccctgattc gatgaacgct ccggcaataa ctgactgtac
    31801 agaattccag atttcatttg catcatgttc cacccaactt tcttgcggga aatattgcgt
    31861 gaactctttt tgagaactgc cgatgtgtct tcctttcttg tcaaagataa ttgctcgtga
    31921 gctagttgta ccttggtcaa tcgccatgat atacgttgat tctgtcattg tgattccctc
    31981 cattatatgc aaacgctttc tttaactact cttatcatac tactgtttta aaaaaagaaa
    32041 ctgtcaaaat tttattcttt ttttcttttt ttgacagttt tttattatga agctattttt
    32101 taatcaattc ttttcttttt tcagcgtctc tattcttctt ttcaatcgaa taatgtcgta
    32161 aggtgacgca aattctgaca gataatattc acactgtttt ttgtttctct ggcaaaatgt
    32221 gatcaccaaa tcatattctt taccttcttc ataacttcca atctcaatac cgccgattcc
    32281 cctcagttct ctgatcagat attgttgaaa agcaatacga taaatcggca gactttctaa
    32341 atcgattcca atcactactg gttttgcaat ataaaaatcg atcatcaaaa gaacattggc
    32401 atactggatc atcaggtaac taagctcact atcttcagct cttttcctcg gcaattgctg
    32461 caccgctgtt tcctgtaatt tcgccagtaa ctgtgttaag gaatgcccga gcattttctg
    32521 ctgctgttcc aaaagccgat cacgctcata gacttcgatc tttccaacaa agaaaaacca
    32581 ttcattgttg atctgggaaa tttggtagcc tactgccttt tcttctttga ttttcaaacg
    32641 acgaggacga taatgccata acatcgtttc ccgaatgtaa gtatctaaaa cagcggttgg
    32701 taactttttg ctccgtgtca aatcatactg ataaaatatt tcttcgtcta ctatcgaaaa
    32761 agaaacaaaa aagctgtaaa acatcattgt ttcgtataca ttcagttctg ctgctgttcg
    32821 actaagatgc atcacgatga ttggatcgat tgcttgataa agccggtccg actgatagag
    32881 taatttcttt tctttcaaag ttgcgtacgt acttttttca ttcaatagtc tttttttcgt
    32941 aatcccgagc cagcaagcaa tctgtgcttc tgctgatgcc gtaaacgttg tttctaatac
    33001 acggtccaat cctagaatga acggtctttt ttctggtgta ttttgcaaaa aaagcggtcg
    33061 ctgatcttcc gggatatatt ggaatagttc ataataaaaa tatcgtatct gtagctcttc
    33121 tccgtataat tgaccgtttt tgatttgtaa tccaaattcc tctaagagct ggttcaattc
    33181 tttgatcttt cgaaaaacag aagactcact gatattaaac gctgtcgcta atcgaacgat
    33241 ggatacttgc tgatgttcta ataaatagac gagcatctta aacttcaagc tttcctgcaa
    33301 taaaaacaat agaatttttt ccaaacttac atcttcgtcc aacacaagca gcgcctgata
    33361 ctcatttcgc tgtacttcta cttttttttc catcattcgg ccaatcaatt caatatcttc
    33421 caaatattga tcaaacgagg cttttgacag ttggacatgc tctctcaaac cattgataga
    33481 ggctgttccc ccttgcagaa caaggtttcg caaaatcagg atctgtaact gctcttttct
    33541 ttctaataat gcttcaatct tcataggcag tattcgccac ctttgaccac accatatctg
    33601 gcacacggta ttctggctgg aaaaatagct catgttcttc taactgttca aacgtccatc
    33661 cttcttctac tgcaattgtc agttggtcaa gaaggtggaa catctctttt ttgctttgga
    33721 gctgtgctcc aagaatcttt ttttcagaat caaatagaaa tttgagttta actttgcttt
    33781 gatttattgc tgtaagcttg tagtctacgt atcctgtttc aattttttgg ggataaaaaa
    33841 tgctctcttc ttctgtcaaa cctacgcttc ctaagaaata gccaaaccac tgattgccga
    33901 ctggacgata ggttccctga tcctttgtct gtgagccact aattgtcttg ctgacatttc
    33961 gtgctgtacg gacagcgtta tttactagag aaacatacat tttttcattt gttggacgaa
    34021 aagttacttg gatcgcatcg ccaatcgcat aaacgtcttt ttgagacgtt tgcaagtagt
    34081 catctaccca gatcgttcca tcatcattca atgttaattg ttcttcccac atctgattgt
    34141 cgggacgaga atgattagcc agcaaaacaa gatcatagtt ctcctttctt ttttccgtct
    34201 ctacaatagc ggtttcattt tcggtcaaag acacaacttg ttcttctaaa aaaagtgaaa
    34261 gcccttgatt tttcatttcc tttactaacg gttctgtcat ttcaggatct agataacgaa
    34321 aaagaattga ctttcggctt tcgtaaagat ggatttgttt ttttcttgat gccaaccctt
    34381 cagctatttc gattcctgct tgtcctgcac caataattgc aattttcttt gcattcatga
    34441 tcttttgctg aagagccgtt acgttttgta tctttttaac tgggtgaata agcgttgatt
    34501 ctgcagaaat atttcgaaac ttttgatttg aaccagtcgc tagaatcaaa cgatcaaaat
    34561 ccaatttttt tcctcctgct aaaacgactt ttttttcttt caatcctatt actgtctttt
    34621 ctgtgtaaac atggattcga tagcggtcag tcagttcttc tttcgtgatc caagaaagtt
    34681 gtttttcact ggtaaccttt ccttttaata tcaaattgaa cccgctggga atccatccta
    34741 acttcgattg cttttcaatc aaatatattt cacttgttgg catcaattgg cgaagataaa
    34801 tagccgcatg aatccctgca aacgacccgc cgacaattac aatgttcatc tgcattcctc
    34861 tttcttataa ggtgttctac tgctaacttc tcaatcagaa aacacagtat tcataactcg
    34921 ctttcaacct tatgatacat agcgatgcag cagaatcaac cctctccatc ataccgtgtt
    34981 ctaggtctgc ttctcaataa tgtactagtg gacctaattg aagagtatca tttctgaaga
    35041 gatgtttcaa aaaatgtact cttataaaag aaaaaaactc gccttttacg tacctctgtc
    35101 caaataggaa acagaaaaga acgaaaagac gagttttagc gtgtgtaatg taatagttag
    35161 aatagacaca tcatttattt ttaattcttt aatgcttcaa caactgcttc gcctaattga
    35221 tgagcagatt gaggattttg ccctgtaaga agccgcccat caatttgaac cacttctgaa
    35281 aaagctgctc cagactgata gtttgctcct ttttctttca aagcatcttc tgctaagaat
    35341 ggtacttcat tcgttgtacc atttgcttcc tcttcttcat tactgaaccc agtcactgta
    35401 cgtccagcta aaatagattt tccagactca tctgtaactg gcaacaatcc tacaacaccg
    35461 tgacaaacag ctgagaccag cccttcattt cgatagattt gtgaagcgac tttcccaaga
    35521 tctattgctt ctggaaaatc ccacattgtt ccgtggccac cagcataata aaccgctgca
    35581 taatcatttg catccacatc atcaggacgt aaggtatttc ccaaggcccg atttctgaaa
    35641 tcttcatctt cataataggc ccaatcgatt tcatccatat tcaaaacact ttgcggttct
    35701 aaaggtacat atccgccttt aggactgaca aaatctgcat cgatcccatt ttttactaat
    35761 acatcataaa aatgagtcag ttcacttaac cacaaacctg taggacgctc gatcttttcg
    35821 tacttttcta catttgttaa tacgatcaat actttcattt tcccatcctc tttctataaa
    35881 aattgcgtta ttgataacgt gctttcaaga aattatataa tgggcttggc aaataaagct
    35941 ctttatatgc tttttcaaaa ggtttcgtta caaattcatc ctcacggttt tccaataatt
    36001 tctctgccca gtcaggatcg acgatcattt gctgtccaat tgctgcaagt tctgcatatt
    36061 tcaatacctg ctctacatct tcgcgattgc ggatcccacc gacaccaact aaagggatct
    36121 ttccttgaat cgtgttatgg accacttcaa gaatcgattt atcgttgtat ttatcagaac
    36181 gagctattcg atcatacata tttaatgaaa catgcagata atctagtttt gactcacgta
    36241 atcgttcaag aagccagatc gtgtcttcaa aacggatacc tggtgtttca tattcttctg
    36301 gtgagaaacg ataccctacg atgaatggtt ttttagcata ttgttcaacc gctgagaaaa
    36361 ccgttgttaa taattcttca ataaaacgat aacgattttc caagctaccg ccccattgat
    36421 cctctcgtct attcgaatgc ggagagaaaa attgttggat caaatacgta tttgctccat
    36481 gcaactcgat tccatcaaat cctgattcaa tcgctctacg tgtggctttg ccaaatgctt
    36541 ggattgtttc aacgatttct tcttcactca ttgctcgtgg tgtttccgca tcaggacgtt
    36601 ttgctgcaac tgcacttgca gatacaggct gttctccaga taaagttgct cgacttgtca
    36661 ttcgtccacc gtggaaaatc tgaataatcg cttttgcgcc ttctccttgg attgctttcg
    36721 ctagctcact taatcgagga atcatttcat catgagcgat gctgagttca cctggccagc
    36781 cttttccgat atcttggaca tttgcagcac cagtaataac agcaccaaga cctttagaac
    36841 gttgtttata ataagtgatc tcatcttcgg tgatcactcc attgaaaaag ctgagttgtg
    36901 tcgtcatagg cgacagcatc aatcggttct tcaattgaac tcctgaaggt aaagtaattg
    36961 attgatcaaa ttgtgacatt gtcattcctc ccataattcg ctctgattaa cctatcgaga
    37021 atcatctatc attaaaccac tcgattagtt gtacatgcaa ctaatttgct taaaaaattt
    37081 tatttttttt gtaacttatc tgttgcatca ttcattgtct gggctaattc tttacttgct
    37141 tcatttccca aaactgcttt gtatgactga tgaagttctt cccagctacc atcgacttcc
    37201 ttagcaaatt ggcgtccttg ttctgtaaga taaactaatg acaagcgacc ttcgctaact
    37261 gttttgacgt atcctttata ttctaatttt tcaacaaaac gagcaatcgt tgatggggcg
    37321 gaatagagca tttgtgcaat atctttttgt ggtattccat ctttttcttt taatatcaat
    37381 aaaataaaac cataagttgg tgccagacct gtccttctaa acgcttcatc agctaattta
    37441 ttcaacatgc gatctagctt tttcacgcta aagaaaagac attcatctaa cgctttttca
    37501 attggctttt ccatttcatc ccctccattg gcgtacatat catagtatga tttttatttt
    37561 ttgtcaaaaa acacggaata atgtccgcct cctctgtcta gatttgaaaa aaagaagtag
    37621 ccatcttcaa agaatttcgg cttgttttcg acaaaactcc ttctggaaca ccgtgaatca
    37681 gaggttgtga aaaagtcgtt tagttttgag tatgaagaaa aattttgtga aaatggcttt
    37741 ccacattttt gcataaattt ggcttaatac cgaaaaactg gcttttgaac accgtttata
    37801 tcagaggttg tgaaaaagcc gtcctgcatc aagtaataag aacagccaaa caaaaatagt
    37861 tcctcatatt ttgtcgtttt ttgagctaat gccgatggtc agctgattgt acaccgttta
    37921 ttgagaggtc gtgagcctgc cgttgaactc cgagtcacaa ggagcaattt caaaaaacag
    37981 cttctcatgt tttatgacta tggtgacttg tgatcgagga gttggcagga gaatactgtt
    38041 tattcgtaaa gaaggggctg tgacaagact tttgtcacag tcccttattt ccttttatta
    38101 taggatttcg ccatttgatt ggatgacttg tctgtaccaa tcaaatgatt ttttctttaa
    38161 ccgtttcttt gtgccattcc cttcgtcatc ttgatcaaca tagatatatc cataacgttt
    38221 tgacatttgt gaagtagaag cgctgacgat atcaatgcag ccccacgacg tataaccaaa
    38281 taaatctact ccatctttga tagcttcctt catctgctca atatgctgct tcaaatagtc
    38341 aatgcggtaa tcgtcttgaa cggttccatc ttcttctact ttgtctatag ctccgagtcc
    38401 gttttcagct atgaacagtg gtttttgata cctatcatat aattgattca aagcaattct
    38461 caaaccctta ggatcaatct gccagcccca ttcacttgat ggaagatacg gatttttaat
    38521 tcctccagtt attaagtttc cttggacccc ttcccaattt tctggatgag cactgactgc
    38581 actagacatg tagtagctaa aagaaacaaa atcaacaggg taggctgcta agatttcttc
    38641 atcacctact tctattttta agttgacacc tttttcttca aacattcgtt gcgtatacgc
    38701 tggataatat cctcttgctt gaacatcact aaagaacaaa gaagttcttt gctgctcaat
    38761 tgttttttga atatcatccg gatcacaaga atacggaaca agaagctgat agctgatcat
    38821 acaaccgact tgtgaacctt tgataatttc atgacaagct tttgtagcta aagcacttgc
    38881 tataaactga tggtgtgcac cttggtattt cgcttgttcc aaatggggat ggttttcttc
    38941 aattactcct acgctaacaa aagggtgatg ttttacacag ttgatctcat tgaaagtcat
    39001 ccaatatttt actttatttt tatagcgttt gaatactgtt tcagcgaaac gaacgtaaaa
    39061 ctgaataagc tttcgattag gccatccacc atattctgta accaaatata acggcatttc
    39121 ataatgggaa agagaaacga ctggctcaat cccatatttt agacattcgt caaacacttg
    39181 atcataaaaa aataatcccg cttcattggg tgtttcttca tcaccatgag gaaaaattct
    39241 tgtccatgcg atagacatcc gatagcattt aaaacccatt tcagcaaata aacggatgtc
    39301 ttctttaaag tgatgataga aatcatttcc gtgtctttta ggataataat acttgctgtt
    39361 gggatcctgc gccgctttta cttgctgatg cgtcatcata tgccattgat ctgtccattt
    39421 ttctttaggt aaatcgctgt cgaatgtata cacatcagac acagataatc ctttttcatc
    39481 tacatcccat gcaccttcac attgattggc cgctgtcgct ccgccccata aaaatccttc
    39541 tggaaatttt ttcatatcga tccccctaaa cttgctagtt ttcttgtttg attatttttc
    39601 ttatgactag taatgatatt tttgaatcta ctactatttg taacaataac cattgtggtc
    39661 ggatcatatc cctctttgat taattcttgc aaatctactt ccatcaataa atcgccttta
    39721 cgtacttttt ttccatcaga tactgcactt tgaaagtatt tgccatttaa attcactgta
    39781 tcaataccga tatggatcag tatctctgct ccttcttcac tgactacccc aattgcatgt
    39841 ttcgttggaa aaactgttga aacttccccg tttacagaac tgtagatttt tccgtccgtt
    39901 ggaatgatcg caaacccttc tcctaaagat ccactagcaa atgttggatc gtttacttca
    39961 gataaatcaa ttatttcacc tgctgcagga gtacttaaca ctatatcctt tgaggattct
    40021 tcttcgattt catccttgta gccgaaaaga aaagttagca tacaggaact gatcatcgct
    40081 aagaaataac tagcaactag ccaaacaaat ccttcaccaa tataaatcgg gaaagacaaa
    40141 atacttcttg tagcaactgc caaagcaccg gctcctgcgg caccagctac tccaccaaat
    40201 atagctccac atatacaagc aatgtaaaat ggtcgtttat atttaagagt cacaccataa
    40261 acagcaggtt cagtgattcc aaataatgct gtgataaatg cagataaaga taaacttttt
    40321 actttcttat ttttcgtttt caaaaatacc ccaagtactg ctcctgcttg cgcagctacg
    40381 gcagtcatac atgctggacc tagcgtatca cgaccgtaga aagaaagatt gttggtcatt
    40441 actggtacaa gtccccaatg taacccaaaa atcactaaca cttgccaaaa tccgccgata
    40501 acagcaccag ataaaacagg gctaaagtta taaacagcta aatatccagc tgcaatcagc
    40561 tgacttgcat aatctgcaat tggacctaca actaataaaa taattgggac catcacgatg
    40621 atacaaatga atggtgtcaa taaatttcga atactttcgt gcaagctttt gcgaatctta
    40681 ggctcaatat aagaaagaac ccatacagct aaaattgctg gaataaccgt acttgtatac
    40741 cttgctagaa tcacgggcat ccctagaaat cgcaaggtta tgctatcact atatgcactg
    40801 acaatcgtag gataaacgag agctgctgca ataaccatag cgatgaaacg atctgtattg
    40861 aacttttttg cagcagtata tgccaaaaat ataggcaaga aatagaaaaa tgcatcagct
    40921 gctgcattca aaatgatata agttcctgat tcagtagtta ataaattcaa actcgtacat
    40981 aaggcgagta ctcctttgat caaaccactt cctgccaaga cgcctaaagt cggggcaaaa
    41041 acagcggcga tcatgtctat aaaagagttt aaaatgcctt ttttctcagt tcctctcttt
    41101 ccactagatg catcatcttc tagtttcatt tgtttggata atacgtcata cacttcattt
    41161 actgcatttc ctactacgac ttgaaacatt cctccagctt cgactacagt gatcacacct
    41221 tctagttgct ctaccttctc cttatctgcc ttcttattat cttttagggt aaagcgtaac
    41281 cttgttgcac aatggtaaac attgctgaca ttttcttcgc ctccgacaaa tcggacaata
    41341 tctttcgcta attgtgaata gtccattttt acttccccct tgttaattaa tgccgtagca
    41401 atccttctta caagataagt atagttctta gaaaacggtt tctccattca attagtaccc
    41461 cttctaatag cgaacgaaac tgtacaatag tgtgtatggt ttacttagcc gagcaaatca
    41521 ctcactgctt gaaagaaaac aagtatatcg tttctcttat agtcaaagga gacaaaaaaa
    41581 acacgcttga tcttcctttg ctgatgtata agtggtatct caagctgata ctctgtgatt
    41641 tttgtttcta cttggctttt gataagacag cacaacaaag tctcggcatt taacggaagc
    41701 ataactaggt cagaactagg agagattagt tgctgaatgg aatctatctt tttatggatt
    41761 tttatttgat tttcttcttt gtagtaatga tcaagcagtt ttgttttctt tttttcttca
    41821 actatggtca gcttttcacg caaaatctga taaatctccc aagattcaaa ctcatctaga
    41881 acactaggta gataaatcaa atcatcccac tcaaaaataa gctcttgctc agtagtcaaa
    41941 attgcatcat attccgttat tttgtttgat tgatttttga aaagatacac tggttctatc
    42001 cggcattctt tgatccacat gttcatactt tgttgaatct gtttttttag tgtattcaaa
    42061 atactaattg gctggttact aacaatcagt atctcccctt gttttcgaaa aggattcaac
    42121 gcttcggcaa gatacaaaac aaaataagcg ctttcagcta aattgggacg taattgaaaa
    42181 tgtattggga agaaacgccg aattaaataa atttctaaag gataacggga gatgatcttt
    42241 tgtacaaaat gattcatggt attatgtccg gcatccatcc tcgttttcat ttgtttgata
    42301 tgggttagca aaaattctgt ttcatggaac aataacgaaa caggaagatc taaaaaacga
    42361 ataatcgttt gctcaaatgc tcttagattc ttctctattt ctttgttttt ttcatcatta
    42421 atcatcaaat aatttaactc taatagtcga ttttcaattg cttgtttttc ttgattggaa
    42481 aaagaatagg gtagttctga tgataacttt tttgtgaggg tctctaccat cggaataaat
    42541 aatgtatacc tgtttgtttt ttctaaaagt tcttctcttc gaagaatggt caaaacgaga
    42601 taccgagaaa atcgtatgaa gtcctctcct gaaacaatat aattatatga tataagaacc
    42661 tcttttaatg tcttttggac agtcggcatg atattggaaa aaattgtact gatttgttga
    42721 ggaaaccttg cgtgttggat caccgtttct gttccaacaa gagataagaa aattcttttt
    42781 gaattttctt cagcaatgat ttttagtcct tttgtcgacg aaacttccag ttctaattta
    42841 ggattgcgct cgatccaacg caaaatcgtt tttatttgta atgatacggc tgtttttgaa
    42901 agaaagaaaa tgtctgctat cttttgcata ctgacatacc ctttttgaaa caataagtac
    42961 gtcacaatag ttgaagctcg gaaatccatg ctggaataga ttttatgttt cgtcacctct
    43021 tgtatgattt gctgtttagt ttcagattca attgattcta aaaaataacc tgaacgttta
    43081 tttgactgga taatgatttt cttctcgtag atagcaagca tatttttgat ttcagtttgg
    43141 atcgttttct tgttggtacc taaagcttca gctaattctt cgcttgttat ccaatgattc
    43201 ttatttctta atactacaag aatttggagt tgtcgtttat ttaagtccat ttgcttacac
    43261 ctcctctttg ttataaacat acaggaaaaa cctctcaaat gacaatagtc acttgcagag
    43321 gtttaaaaat catttgaaga aagatctata ttcaaggttt ttaccattag actggataat
    43381 ttgtttataa tattcaaaac tatctttttt caatctccta aagcttccgc tcccatcatt
    43441 ttgtctatcc acataaataa agccatatcg cttcctcatt tcccctgttc ctgccgatac
    43501 gatatcgatt ggtccccacc ataagtaacc aatgatttgg caaccatctt ttattgcctc
    43561 agcaatttcc tgaagatgta tttttagata ctcacaacgt tttggatcgt ggattcgatt
    43621 caattcatct ggtgcttcat ctagtccaat gccattttca actatgaata atggtaattc
    43681 ataacggtct gtcaattcat tcatgacata acgaaaccct agaggatcaa ttggccaact
    43741 ccaaggttcg ggagattttt ccttcaaaaa gggattatcg aaaccatttg ctccgccagt
    43801 atctacgcgc atttctgctt cttttttata gacagcgcta cgataataac taaatgcaat
    43861 ataatctgcc gtgttagctt gcaagcactg ttcgtctcca tctaacatta ctggtgcaca
    43921 gtcttcttcc ttccatgtcc tgtaaatata agctggataa tgccctcggc acatgacatc
    43981 ggagaaaaac catgaattgc gtttaaattg cagtgaacca aatacattct ctggatcaca
    44041 gtcatatgca taagtcgcta atgcagaaaa gctacacata atacccatct tagcatttgg
    44101 atcgattttc tttaataatt gagtagcacg ggcgttcgct agaaacatat gatgacaggc
    44161 ttgataaatc actttttttg ttagtgtagc aatgggttca agtttatctc tagcagggaa
    44221 tgtaaccaat ccagcagctg cataaggcat acgaaaagca ttattgatct cattaaaggt
    44281 catccaatat ttcactttcc cttggtagcg ttcaaagacg gtctgcgcat aaaattcaaa
    44341 aaagtcgatt aattttcgat tttgccaccc cccatactct cctaccaatg ctaagggggt
    44401 ttcataatga ctaagagtaa ttactggctc gatatcatat cgatttaatg tattgattag
    44461 tctgtcataa aatacgagac cagcctcatt tggcttctgt tcgtctcctc ttggaaatat
    44521 tcgtgcccat gagatgcttg ttcgaaaagc ttttaaacct aactccttca gtaaacgaat
    44581 atcctcttca aatcgatgat aaaaatcaat cgcttcatga gaaagataat ggagtgattc
    44641 gtctaaagca atctcccaaa tctttttttc ttcattccac tgaatactag gatgctggtt
    44701 catgatcccg ataagcgtat ctgtcacatt aggtaatttg ccgtcttcca accatgcacc
    44761 ttcacattga ttagcagcta ctgctccgcc ccataaaaaa ttttctggaa atatttcctg
    44821 atccataact atctctcctc gctatcaaca atttcttact tgaagtatag ctcgattcat
    44881 caaaacaaga tattctaact atttcggcag aagagaagaa aaaaattgaa tgctactctt
    44941 catttttaat atttatatat aacaaataca taagacgatc cccgaaagaa aacactcgtt
    45001 aaccatctaa gcaaacgatt tattttactt ccaacacaaa tgcttcataa ggtcgtaaat
    45061 caactttgcc gtctggtaac tgtttcagag gataatttga cacaataacc cttaaagctt
    45121 cacgtggaat agtgaacgtc tgcttttcac tggacatatt acaaataacg agccattgct
    45181 ggtcttcata tatgcgagaa taggcaaaga catgctcagg cgtcttttcc actaattcat
    45241 agtctcccca gacgatgatg tcatgttttc tacgcaaatc gatcaatttc ttgtacatat
    45301 aaaaaacaga atcttgatct gctaacgctt cttctgcatt gatttcttta taatttggat
    45361 tgactcgaag ccatggaatt ccagtagtaa acccagcatg ttcacgggcg ttccattgca
    45421 taggcgtcct agcattgtct cttcctttcg ccttgattga ttccaagatt tcctcttttg
    45481 taaatccaga agaaatcctt tcgttataca tattgattgt ctcaatatct tttgcttccg
    45541 cgatatcatc gattgggcaa ttcgtcatgc ctaactcttc tccttgatag atataagggg
    45601 tgcctttcat catatggagc aagatagcaa acatcttggc actttctttt cgatacacat
    45661 cgtcatttcc ccaacgagaa acaattcgcg gaagatcgtg attattccaa aataaactat
    45721 tccatccttc atcacctaaa gatgtttgcc atttggataa tacttttttc agttcagaga
    45781 tactcaaggg tttcaaatcc catttgtctt tgccttcttg ctgatctaat cctatgtgtt
    45841 cgaattggaa gaccatggat aattcatttc ttttaggatt ggaataaagt ttagcgattt
    45901 cggtagttgc tccccatgtt tcgccaacag tcatcagatt tttgtcacca aaagttgctt
    45961 gattcatttc ctgaagatac tcatgcagtt taggtccatt acttgtgatt tctttatccg
    46021 gttctttgcc aatcatatcg atcacgtcca tacgaaagcc cccaatacct ttatcgatcc
    46081 agaaattcat catttgataa atctcttggc gaacctgttt atttttccaa ttcaaatcag
    46141 gttgacgctt gctatacaag tgcagaaaat attgccccgt tttttcatcc aactgccaag
    46201 cagaaccact gaatattgag cgcaatctat taggctcttt tccattgacc ggatcacgcc
    46261 aaatataata gtcccgataa ggattttctt tatttttacg ggcctcaatg aaccacggat
    46321 gttcatcaga agtatgattc accaccagat ccatgatgat acggatattt cttttctttg
    46381 cttcttcaat cagttcttcc atttcttcca tcgtaccgaa ttctgccatg attgcttgat
    46441 aattactgat atcataccca ttgtcatcat tcggagactc gtatactgga gaaagccaaa
    46501 ttgcatcaat acctaaatac gccagataat ccaacctgga aataatcccc cgcaaatctc
    46561 caataccatc ttgatttgaa tcttgaaaac ttcttggata gatttgataa acaactgaat
    46621 ggtgccacca tttttgttcc atgattttcc tcctataaat ggatgtttct attttttgct
    46681 taatcattta ttttagtctc tctcactaaa aattgtaacg ctttcaaata gctattgcac
    46741 cttgttatcg gtaacagaat aaaacaaaaa aacagctgag gaaattccct caactgtttt
    46801 ttgaaaggat tgatttatgc agggaagaat gctgatttca caacttcttt ataaacggtg
    46861 ttcactcagc tgtcccttgg tattagctca aaaaacggca aaatataaga aactattttt
    46921 tcgttttttt ctctaatact caggccagaa cgctgatttc acaacctctt tatttcacat
    46981 tcaatatcca catgaatccc acaaatacaa agaacagacc atacatgatt ggagatactt
    47041 cttttcctct tttagctgct aacatggtaa ttggatagaa gataaaacct aatgcaatcc
    47101 catctgaaat actataagtc aaaggcatgc cgatcaagat caagaatgaa gggatcgcaa
    47161 tctctaagtt tccccattcg atttgtcgca aagattgtgc catcaatact cctaccataa
    47221 tcaatgctgg tgcagttact tgtgaagtaa caactgatag taatggagaa aagaacaagc
    47281 ctaacaagaa gaaaatccct gtagtaatag ctgtgatacc tgaacgtcct ccaacggcga
    47341 taccagctga tgattctaca aatgcaccaa caggagaagt accaaataag gaacccgcaa
    47401 gcatagctgt tgaatcagaa gctaaagctt tccctacacg aggcatcttg ttgtctttca
    47461 tgaaacctgc ttggtttgct aatccaacta aagttcctgc tgtatcaaag aaagtcacaa
    47521 gcaagaatgt cagcactacg acccacattt gaagagaatt gatgtcccct acatgtttta
    47581 atgcaactaa aaatgttggt ttcaaacttg gtgctgcggc aacaatttca gaaggcattg
    47641 gaatcaaacc tgtgaccaga cctaaaatcg ttgtagctgc catcccgatg aagatgccac
    47701 ctggtacacg ccgaacaagc aagatagcag ttacgactaa tccaaaaatc gtcaaccaag
    47761 tagaaccaac gttgagtgat cctaatccta ctaatgtaga ttcattcgaa acgatgatcc
    47821 caccttcgct cagaccaagg aaagcgataa atagaccgat accgccagaa atcgcatatt
    47881 tcaaatctgc tgggatcgca tcaatgatca tttcccgcag cttgaagatt gtgatcaaaa
    47941 taaaaatcaa agaagcaacg aatacgccgg ctaatgctgt ttcccatgga atccccattc
    48001 ctaaacaaac agaataagca aaaaaagcat tgatcccaag agcaggtgcc gttccaattg
    48061 gataacgggc taataccccc attaaaacac agccgatcgc actggctaat gcagtcgcag
    48121 taaacactgc tccttcatcc attccagaag cacctaatac agttggattt acaaataaga
    48181 tataagccat tgagataaat gttgtaaatc ctgccagtac ctcacgtttt accgtggtgt
    48241 tcaatttttc tatttcgaag taggaaagta ttttttcctt catcttccat ccccctaaat
    48301 ccgaacatta taaataaagt ccgttaaaat ttcgatttat taataaaaca acgtgtttta
    48361 tcatatacta aaacaaaaca taagtaaaca aaaaattcgg attttaagca aaatccgaac
    48421 gttccatctg attaaatccc tttatctcaa agttcatgaa cattcacttt ggattacaag
    48481 aatttcttta ttgtgttaat aaagtttctt cattctagtc tcaaaaatca atagtgtgat
    48541 ttgattttac catttcgttt ctgttcttct ttgatgaatt cttttgtatc gacaggattc
    48601 agattattta gtccgccaaa acctgtatcg accatttttc cccagccttt tgtcttcttt
    48661 tttcctgatt tgagattctt tgctcgaagc ttctcactat gttttgctcg ccgatacttc
    48721 aaataacctt ctaatcttcc cattagatcc actgtttttc ctccttttta ttcaatcaga
    48781 cgactcagct tttcctataa caaaataatt gccttcaggg tcagaaaaat tgaaagtcaa
    48841 gatgccattg ttatctgtga tttctcctgg ttcttccatg ttctcgtaga tagtttcaaa
    48901 ttcatccgta aaaaatacta aagaaggcgg tggtcctaat acctctggtg aaaacttctg
    48961 cacaaatact tttgggaata cgcctaattc taattctttt gagatgctga gtacaatact
    49021 cttaaattct tctggcaatt cgattgtttc agaaatttct gcaccaattt tttctacaaa
    49081 gaatcggcaa atcatctcta cgtcattgac ataaagcatc acacgtgttt tttgtatcat
    49141 catttgaccc ttctttctat ttgattttct ttcctgtcta taaactgatt ccattatatc
    49201 acgaaagcgc aaacaccttg tgtttgatac tattcaagaa aaataaagca atagtttcta
    49261 ggattgcttt cctccacaaa ctttttttac aaaaaaaaaa cggcaatgaa tgccgctctt
    49321 cttatttcga ttcttttata attctgcttc tgattcatct ttggttagtg tgtgtctaac
    49381 actagttacg ccaaatgttt gatcgatttt ttccttcaac gcttcgattg cctgtgcgcc
    49441 acgtgccgct tgttcagcat tgatggattc aatgaccagc accgctgctt gtgtttcttc
    49501 cgtcagcatc gttctttggg cttcacgcca gttgagacag cgacagatcg ctccttgttc
    49561 atcatagtag atgatttctt ccggaagtgc cggagcatcg gaatctgcac ctaaaggcag
    49621 gaatgattcg ccaccttggg cttttcctaa atgcagattt cctgcgatct tttcgatatc
    49681 ttctccgccg caaggtacgc caaaagacaa ggaaatacta ttatagatat ctacaagcgg
    49741 attgattggg aaaaattccc gttcttgatt tgcacgtttc agtaaagctt caatagaaga
    49801 acgtgcacct tttttagtct tgaatgtggt aaatgcctga cgccactgag caatgacttc
    49861 gttttggctg aatgtttctt ctgtaaggta atttcttgct tcttttgctg cctcattcaa
    49921 taattgatga tacgtttctt cactttcttt tgttacgtgg ttatcgatac catttacgga
    49981 taagatttcg atggttgctt caggaaatac ttcccagaaa ttggtatcca ctattacttt
    50041 tttcatctgt tcacacctct tgattagaat aattgcttga tgaatagata gtctgtttgg
    50101 ggatcatctc ccatataaaa aacatgttcg ctgtatttga taaatccttt tttacgataa
    50161 aaagcgagcg caacatcgtt gtgttcccaa acaccgagcc aaatggctgt tttttgcttt
    50221 tcttttgctt tttcaatagc tgtatctagt aaaaatgtac cgataccttg atgtttaaat
    50281 ttttttcgta catagattcg ctcgatttct aaaaaatgat cagccatttc ctcagattga
    50341 ctcgttcctg tatttagttt caggtaaccc gcaggctctt gatcgatact cactaggaaa
    50401 aaatcggttt ctttatcttt tagctcttct gtaagttttt ctagtgcata agcttgtgtc
    50461 aagtaatcag ctaaatgctc cggtgaatta tcttttccaa atgtatctgt aaatgtttcg
    50521 atactaattt gttgtagtaa gtctacatct gaaggcgtca tttttcgaat ttcgtattta
    50581 ttcacggctt cttcctttca atagatcctt ttattgcctt ttttgacaaa attccaatct
    50641 tcgctaacat tcttgcatac tttatttaaa agatattcca attgttttgc ttcttcgtca
    50701 gaaagaccat ttaatgcgac tgcattggag tagttgtttt ctcgaatgat gaaaggatag
    50761 atttctgctc cttttttagt cggatagagt ttcttgattt ttttattttc tttatcttcc
    50821 aaacgttcga tcatcccatt ggattctaat ttcttgattg ctcgggcagt cgttgtacga
    50881 tctactttga tcatttctgc tagtttttct tggatgattc caggattttc gcaaatacgt
    50941 actaaataaa gatactgtcc tcttgttaaa tcgacttctt tgaattcgat attgctaata
    51001 gaatctagcg ctcgggcaat cattccgatg tctcgaagga tttcagccat ttcatcccac
    51061 ctttattttg tttgtaagac tagttcacct ctttttgttg caaatgcaac tattttcaat
    51121 aaaaaaatca agttcttttt taataactag taaagtatat tcttttcttc ttttacgaaa
    51181 aagctcaatc acaatagatc tggtttttgt tttctaaaat aagtaactgt ttcttcgttg
    51241 ttcgcttttc tgatagcttt ggcaactctt ctatactaaa aaatcccatg ttggaagttt
    51301 cattattctc aataaacttg gcctcttcac cgtggatcgc acaagcaaaa acaagtttat
    51361 aatactgaaa aagctgtgga atatcttttt gtttattcgt atcaaaaact gctcgcaact
    51421 gagtagtttc tactgttaat cctgtttctt catagacttc tttacgcaca ttttcttcag
    51481 gagacaatcc tatttcagca aatccaccag gaagtgacca ttctttcgtc cgtttatctt
    51541 cgattagtag gaccttgcca tcttttttga tataggcacg aacatctact tttggtgttg
    51601 gatgtccttc tccaatcgtt gtgagcgctt ttatttcttc gaaagtttct tttcctattt
    51661 cactgatcag ttccaatgaa atcgtccgga tctcctcaaa acgctcttta tcaaatacat
    51721 cttttccata atatagacca gcttgagaaa gtgcgagtag tcttttgtat tgagccaact
    51781 tcttgttcat tctcttccct tcttttttag caaatgtatg actatgtaat caagtataga
    51841 agactggttt aattacggca aataaatata atgaaatctg caataaataa aagaatgtta
    51901 aaaaactcga gaacaaaaga cattcgactt ctctggggct gtgaataaat ggcgttcaaa
    51961 agcttgcatc tgcggtaata agccccacca aacgaaaaat atgacgagct attcttgtct
    52021 ggctgttctt attaattgag gcaggacagc tttttcacaa cctccccact aaacggtgtt
    52081 ctcctaccaa ctcctcggtc acaagtcaca atattcatca aacatgagaa gctgtttttt
    52141 tgaaattgct ccttgtgact cggagctgaa cgacaggctc acgacctctc ggtaaacagc
    52201 gttcaaaagc caatttttcg atattaagcc atttctttgt tacttattgt cattgatttc
    52261 tttttctaat ttatccaata gtggagtgta atccacttga gtatagtctg ttacatcaaa
    52321 ttcatatagt gttcctaact ggaatttgtc atattttcgg tcggcgatga tctttttgaa
    52381 tgcttctttc gtaatatgat tggtcccttt cgttcgatct tccaatacgt caccatagtg
    52441 ataatgatcc atgatatagc tcaaatgacg atctgattca cgatcacgtt tgtaccgacg
    52501 ttgccataac acttcaaagt ctgctgttag gcgaatcgtg atcacctgat atccgtatct
    52561 atctgctaat tcttggagtc gtgctttttg cttatcacta aaaggatact cggacacaat
    52621 cactttcttt cctgcttcca tatacaaatc aagtgctttg taatagaaag gataaacttt
    52681 cgtcctttct tgttccgccc gttcttccaa attgttaaac ccgatggatt ctgcatagta
    52741 ttccttgatt tcatcgagcg tgatggcata catatctgga aatcgttccc gtagtttatt
    52801 cataagatat gtttttcctg taccaggact accagccaga agaatgaaat actttttcat
    52861 ctcatttatt tcctaagtta attggacttt ccaagttcat aaacagtcca atcttatgct
    52921 tgacaatttc ttttactgct tcatttgctg gaatcacatt atggcgaaga gacttgttga
    52981 tttctgtttc actaaaggtt tctttagcta ctttcgtcca gttgactaaa agctccgttc
    53041 caacattgaa tttgcggatc ccgttattga tcaattcagg ataatcttct tctttcacac
    53101 ctgttcctcc atggataact agggggacat caactactgc atcgatttct ttcagcaagg
    53161 gaatgtttac ttctgttttt gatttgaatt gtccatgatt cgtaccgata gcaatagcta
    53221 atgcatccac gcctgtagct tctacaaatt tcactgcgtc ttccggtctt gtatatacct
    53281 tgtcattttc agcgacatgg attccttctt ctgtaccgcc gattgttcca agttctcctt
    53341 ctacggaaac accgtgcgca tgggcatatt ctactactgc ttttgtcttc aggatatttt
    53401 ctttgaaagg cagatgggac ccatcataca tgacagaagt atatccgctg tcgattgctt
    53461 ctttgatatc atcaaagtct cgggcgtggt ctaagtgcaa gactgcatca accatttctt
    53521 cttctgcaat agctgtcatt acattgacta acacatgcat gccgatatat ttagcggtat
    53581 cgacacttgt ttgaataatg atcggcgaac ccatttcttt tgctgcgcct agcatagcag
    53641 gaagcatttc taggttatgc gtattaaaag ctccaactgt aaaattcaac tcttctgctg
    53701 tttttgttac ttctttcaat gttgtataca tcttttattg ccaccttatc tttttatttg
    53761 tttcctttga tcgttacttg ttttgcaatt tgtcgcatct catccatttt gcccatgtag
    53821 taatcgatcc cttgatcatc accagcacga gcagcatctg cacgcttctg gttatagagg
    53881 ctcatcagtt ttttataccc atctccgatc gtctgtttat tttccaaact cttttctaaa
    53941 tattggatgg cttgatcgtt cacatacaat tcagaaaatt taagtccaac ttgttcataa
    54001 agtttcgcta atttatgctt atcttgggta gtggaaatct cttgtttcaa ttgtgtaatc
    54061 tctgattgaa tcttttcggt cgcttctggc gatagggctt tttcttcttt tgccagaact
    54121 tttttcggtt ctttttcttt tttcttaaaa aatccaaaca tcattttccc tactttcaat
    54181 taaaatgctt tcaaaactgg gcttaagatc caggcatata agagtgctgc ggctactgta
    54241 tctacatcgg ttgctgtagc attgttgaat cccatcgaat taaagatcgt tactagcaaa
    54301 gcgggcaata atgtaataaa gaaaccatga gcaataccgc caatgatcgc tcctcggcgt
    54361 ccgccaactg cgttgccaaa tatccctgct gtccctccgg caaagaaatt ggttagcata
    54421 ccaggtaaaa tcatcgctaa gccgaacatg ggcaaagtaa acatggcaat aatcgtacca
    54481 atcgttgtcg taatgaaacc taaaatgaca gcatttgggc tataaggaaa gaaaactgga
    54541 caatctaagg cagggatcgc atcaggaact aatttcatag ctatccctcg aaatgccggc
    54601 acgatttcac ctaacagtag acgtacacca gctagcaata catacacacc cactacgaat
    54661 tggatggctt gtaaaaaggc aaacatgata tagttttgat ctcctgataa ttcagaagcg
    54721 aatggttcgc ctgcaaataa aacagtgatg atatatagcg ggaccatcac gaccatgaca
    54781 gacaaataag tatcttgcag aaattcgaaa tgtgtcggca acttgatatc ttcgatcgac
    54841 tttttatttt cgcctttctc accaaaaagc ttagcaacac cggcttcaaa taagtacccg
    54901 atcgtacaaa aatgacctaa agcaatatca tttgatccag tgattttacg aatgatcggt
    54961 tgcgctactg ccggcatagc aatggcgaaa caagctccga taaaaccacc gaccaagatc
    55021 aatacgatcc ctcgcagacc ggcaaaatag ccaaagactg tcgtcatcgt tgccatccat
    55081 aaaattgctt gaccagttaa aaaaatgtac ttccattttg tgaaacgagc caaaataata
    55141 ttgaatacaa aaatggctaa gaacgtcagt gcaatatctc tacctaaacc caaatcattc
    55201 attgcttgac cattgataga ttcaatagaa gggatgatcc cttgcatatg aaatccttca
    55261 gtaaagattt tcccgaaata agttaaactt ccaacgatga tgctcgaacc ggcactcaac
    55321 acttgaaatc ctaggagtgt ctttaacgtg ccagagatga cttgtcctgc tgatttcttc
    55381 tgcagtagta gacccaacat agcaatcaat gcaatggtga tcgatgcctg agtcaaaata
    55441 ttttcgatga taaaattgat aacgcccatg
//
LOCUS       DADLIO010000010        54371 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.010, whole genome shotgun sequence.
ACCESSION   DADLIO010000010 DADLIO010000000
VERSION     DADLIO010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 54371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54371
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.010"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(26..328)
                     /locus_tag="JOX41_000739"
     CDS             complement(26..328)
                     /locus_tag="JOX41_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAY6448504.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(353..2446)
                     /locus_tag="JOX41_000740"
     CDS             complement(353..2446)
                     /locus_tag="JOX41_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAY6448505.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(2935..3699)
                     /locus_tag="JOX41_000741"
     CDS             complement(2935..3699)
                     /locus_tag="JOX41_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HAY6448506.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(3810..4679)
                     /gene="mdcB"
                     /locus_tag="JOX41_000742"
     CDS             complement(3810..4679)
                     /gene="mdcB"
                     /locus_tag="JOX41_000742"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HAY6448507.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(4704..5780)
                     /locus_tag="JOX41_000743"
     CDS             complement(4704..5780)
                     /locus_tag="JOX41_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HAY6448508.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(5804..6397)
                     /locus_tag="JOX41_000744"
     CDS             complement(5804..6397)
                     /locus_tag="JOX41_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HAY6448509.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(6401..8077)
                     /gene="mdcD"
                     /locus_tag="JOX41_000745"
     CDS             complement(6401..8077)
                     /gene="mdcD"
                     /locus_tag="JOX41_000745"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HAY6448510.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(8067..8366)
                     /locus_tag="JOX41_000746"
     CDS             complement(8067..8366)
                     /locus_tag="JOX41_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HAY6448511.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(8468..10114)
                     /gene="mdcA"
                     /locus_tag="JOX41_000747"
     CDS             complement(8468..10114)
                     /gene="mdcA"
                     /locus_tag="JOX41_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HAY6448512.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(10121..11032)
                     /locus_tag="JOX41_000748"
     CDS             complement(10121..11032)
                     /locus_tag="JOX41_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAY6448513.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            11152..12009
                     /locus_tag="JOX41_000749"
     CDS             11152..12009
                     /locus_tag="JOX41_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAY6448514.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(12196..12558)
                     /locus_tag="JOX41_000750"
     CDS             complement(12196..12558)
                     /locus_tag="JOX41_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448515.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            12904..14343
                     /locus_tag="JOX41_000751"
     CDS             12904..14343
                     /locus_tag="JOX41_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAY6448516.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(14350..16902)
                     /locus_tag="JOX41_000752"
     CDS             complement(14350..16902)
                     /locus_tag="JOX41_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HAY6448517.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(17016..18347)
                     /locus_tag="JOX41_000753"
     CDS             complement(17016..18347)
                     /locus_tag="JOX41_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAY6448518.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(18313..19791)
                     /locus_tag="JOX41_000754"
     CDS             complement(18313..19791)
                     /locus_tag="JOX41_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAY6448519.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(20096..21931)
                     /gene="tdc"
                     /locus_tag="JOX41_000755"
     CDS             complement(20096..21931)
                     /gene="tdc"
                     /locus_tag="JOX41_000755"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HAY6448520.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            22401..23828
                     /locus_tag="JOX41_000756"
     CDS             22401..23828
                     /locus_tag="JOX41_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAY6448521.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(23920..24285)
                     /locus_tag="JOX41_000757"
     CDS             complement(23920..24285)
                     /locus_tag="JOX41_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HAY6448522.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(24282..24647)
                     /locus_tag="JOX41_000758"
     CDS             complement(24282..24647)
                     /locus_tag="JOX41_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HAY6448523.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(24839..25087)
                     /locus_tag="JOX41_000759"
     CDS             complement(24839..25087)
                     /locus_tag="JOX41_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448524.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            25086..25214
                     /locus_tag="JOX41_000760"
     CDS             25086..25214
                     /locus_tag="JOX41_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HAY6448525.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            25271..26965
                     /locus_tag="JOX41_000761"
     CDS             25271..26965
                     /locus_tag="JOX41_000761"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HAY6448526.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            27032..27238
                     /locus_tag="JOX41_000762"
     CDS             27032..27238
                     /locus_tag="JOX41_000762"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448527.1"
                     /translation="MFLIWLDLLPQMQAFEHRLPRGYEKAALHQVIRAAKLKQLLMFL
                     TWLDLLPQMQAFEHRLPRGYEKGV"
     gene            27616..28749
                     /locus_tag="JOX41_000763"
     CDS             27616..28749
                     /locus_tag="JOX41_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HAY6448528.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            28780..29100
                     /locus_tag="JOX41_000764"
     CDS             28780..29100
                     /locus_tag="JOX41_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448529.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(29129..29593)
                     /locus_tag="JOX41_000765"
     CDS             complement(29129..29593)
                     /locus_tag="JOX41_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAY6448530.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(29725..30978)
                     /locus_tag="JOX41_000766"
     CDS             complement(29725..30978)
                     /locus_tag="JOX41_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAY6448531.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(31007..31324)
                     /locus_tag="JOX41_000767"
     CDS             complement(31007..31324)
                     /locus_tag="JOX41_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAY6448532.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(31350..31670)
                     /locus_tag="JOX41_000768"
     CDS             complement(31350..31670)
                     /locus_tag="JOX41_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAY6448533.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(32134..33549)
                     /locus_tag="JOX41_000769"
     CDS             complement(32134..33549)
                     /locus_tag="JOX41_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAY6448534.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(33566..34882)
                     /locus_tag="JOX41_000770"
     CDS             complement(33566..34882)
                     /locus_tag="JOX41_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAY6448535.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(35032..35730)
                     /locus_tag="JOX41_000771"
     CDS             complement(35032..35730)
                     /locus_tag="JOX41_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HAY6448536.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(36019..37008)
                     /locus_tag="JOX41_000772"
     CDS             complement(36019..37008)
                     /locus_tag="JOX41_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-glyceraldehyde 3-phosphate reductase"
                     /protein_id="HAY6448537.1"
                     /translation="MYIADSARYEKMEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQ
                     REILRGAFDMGITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMW
                     EGPYGEWGSRKSIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGK
                     ALYIGISNYNGEDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGA
                     ITFSPLAQGLLTNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQS
                     LAQMALAWNLRQKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            complement(37088..37921)
                     /gene="msrA"
                     /locus_tag="JOX41_000773"
     CDS             complement(37088..37921)
                     /gene="msrA"
                     /locus_tag="JOX41_000773"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAY6448538.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQVERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(38096..39730)
                     /locus_tag="JOX41_000774"
     CDS             complement(38096..39730)
                     /locus_tag="JOX41_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448539.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            complement(39717..41564)
                     /locus_tag="JOX41_000775"
     CDS             complement(39717..41564)
                     /locus_tag="JOX41_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448540.1"
                     /translation="MFFFIFFSYLKVIKIDSFLVYHTSAMKNLTQNLLKKDNSSILKI
                     ELKKENNKSMKISKKAFLLVVLILLSTLYSVNFMRNAQEIYTTGDLSFHLSRIKGLSS
                     IFEGPINYTTFNNYGDGLNYFYPFLTIIPAVVFYGISNNLILSYVLYIWLLNICTILI
                     SFYYGEKFFKKIDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVLYYAYGLI
                     FNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIKFVVVNLV
                     KAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNNDITTYTM
                     GLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPISLLQFPWR
                     ILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAKVIQSKHG
                     HIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKYKAADNNI
                     TYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENKIEITTKY
                     TPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
     gene            41551..43188
                     /locus_tag="JOX41_000776"
     CDS             41551..43188
                     /locus_tag="JOX41_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HAY6448541.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSKGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(43333..44073)
                     /gene="truA"
                     /locus_tag="JOX41_000777"
     CDS             complement(43333..44073)
                     /gene="truA"
                     /locus_tag="JOX41_000777"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAY6448542.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(44264..44899)
                     /locus_tag="JOX41_000778"
     CDS             complement(44264..44899)
                     /locus_tag="JOX41_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HAY6448543.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(45046..46287)
                     /gene="sstT"
                     /locus_tag="JOX41_000779"
     CDS             complement(45046..46287)
                     /gene="sstT"
                     /locus_tag="JOX41_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HAY6448544.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            46485..47483
                     /locus_tag="JOX41_000780"
     CDS             46485..47483
                     /locus_tag="JOX41_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448545.1"
                     /translation="MFLSNFFVRCLFLKKIKKESYGFLTIFVACIMMVLQRILISAVT
                     IPTYATNPGRFYIYTFLQTSVVIGANLIPLYMGYQYQKIARLKVLHYLSRFAFIFLIA
                     TLVCNIFFYVQAGSLNIRDYWLILTPISQNYFTYAVSCTLLFCSIPYTVGFLNKLSKT
                     TIKYLLLFLTIGLVGCSTLFNKDPFALQNGQSILWIFYLFLMGYGLKEWNWKEKVRYK
                     LPQVFISLIVLFGLIILMTQISLIIRGNTDTALRFSKPYSLFAMYYTFSSFLFLEMLS
                     DKLGIKGRGNFLAVFLIVTQVICNFPLVSYRVSTFMKREFPNSGKAWLINIGQFFI"
     gene            47496..49514
                     /locus_tag="JOX41_000781"
     CDS             47496..49514
                     /locus_tag="JOX41_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HAY6448546.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(49574..50290)
                     /locus_tag="JOX41_000782"
     CDS             complement(49574..50290)
                     /locus_tag="JOX41_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HAY6448547.1"
                     /translation="MKKRILVTIGLAFLLAGCTNGNESKKESTKETAKATVATTTTTS
                     TESKSTAASTETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNAD
                     KSAQLEAFMTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEW
                     SESGTGQADYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFN
                     ETANNELKNGFNQIVYGQAN"
     gene            complement(50517..51059)
                     /locus_tag="JOX41_000783"
     CDS             complement(50517..51059)
                     /locus_tag="JOX41_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAY6448548.1"
                     /translation="MNIVEEKFVQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLQQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            complement(51064..51291)
                     /locus_tag="JOX41_000784"
     CDS             complement(51064..51291)
                     /locus_tag="JOX41_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper resistance protein CopZ"
                     /protein_id="HAY6448549.1"
                     /translation="MKKIIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSAKVKEA"
     gene            complement(51370..53250)
                     /locus_tag="JOX41_000785"
     CDS             complement(51370..53250)
                     /locus_tag="JOX41_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HAY6448550.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIMIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDEVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDRFSQYYTPTVLLIALVVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQTGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAKLKQAGAKQLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLR
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSNFESLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLNGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            complement(53439..54053)
                     /locus_tag="JOX41_000786"
     CDS             complement(53439..54053)
                     /locus_tag="JOX41_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAY6448551.1"
                     /translation="MKLTFKPLEKKDYKKAIYFAVEGMNFERYMENELLLNLYGRYFL
                     YMELNRATQILALYAEDELAGVLLAEIKGEKKKHRSFGQQIYVKIFDFLQNIFAKESK
                     GAYETANEQMLAAYLKKHSPDGEIIFLAANPDLKTKGIGTKLLTEFEKREKGKEIFLF
                     TDSGCTYQFYERRGFERLKEKISKIKILDKEIDLRCMLYRKIIQ"
     gene            54195..>54371
                     /locus_tag="JOX41_000787"
     CDS             54195..>54371
                     /locus_tag="JOX41_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAY6448552.1"
                     /translation="MKKTDRRVKKTEKALAETLSTLLVNKKIQAITIRELTETADVHR
                     STFYTHYKDIYDLYD"
BASE COUNT        16640 a        11007 c         9028 g        17696 t
ORIGIN      
        1 tttttaccct cttttctttt tgtatttaga taactccctt atcttgcaga actggggtga
       61 ttttttcttc aatttcattt tttgaaacaa tatttttcaa atagatcatc gccgttttag
      121 gatcaactgc gaacttttcg aactgcgaac gaaaattttc tgctgtgatg atcacatctg
      181 gtttcatgga aactgcggaa gaaatatcac aatggtccag tttggcttct actcctaatt
      241 tgttcaaaac atcctcagca gacatctgtg ctgcaaaact acttcctaaa cctgcaccgc
      301 atacgaataa aatgttcaat ttgttcatct ttgttctccc ccgtatcatt tattatttct
      361 caactactga aaaaagcagt tgtttgaaat cttcgatatt tgtgcattca atcaatcgat
      421 ccaacttctc ttcgttgttg atcaattcaa ttagttcttt catgatgttc agatgcgagt
      481 aggagtctac tgctgccaaa caaaaaataa tctttactgg atccatttca ggattaccga
      541 aatcgattgg ttgctcaatc gtagctacgc tgactcctaa tttattgacc ccatcttctg
      601 gtcgggcatg ggctagtgcc atgtgtttgc caatcacgat atacggtccg taatcattca
      661 ctgcacgaat catcgcttcg acatagcgct cttcgacaat gttttcttta accaatggtc
      721 tagcagctag ttcaatcgat tcctcccaag tagtggcttt ttctttgatc atgatattgc
      781 tgtccgtcaa aatatctttt aacataggct ggatctccct tttgttgatt tctaaattgt
      841 ttgtttcgaa taatttttct aacttgccat agatgattcg atctactcgg ccaccacttt
      901 ctttcatgac atctattatt tgagtgaata actccgtcga ttcatgactg ttaggctcta
      961 accgctgtag ttcttcattt cttttcaaaa agtcttctat aaccaagata ttcgtctcag
     1021 ttaaaatcgg atcgacaact aaaagcggct tatttcgata attcaattga aaggtgctga
     1081 aaaccagatt gacatccaat ttatctacta attcgatttc ttttgaactt aaaactgcag
     1141 taatctcgat ctgaggaaac ttttctttca gattctctgc taacagattt ccagtagcca
     1201 tcccatggtt acagacaacg actgatttat aaacataatt caagtctcgc ttgattacac
     1261 tggcgatcgt cgaaaagtgg atgacaagaa aagctatctc gtcctccagt atcttgccac
     1321 caattacttc ttcgatcgta ggaacaaaat gagtgactgc gcggtagatt gggaaataat
     1381 ttgttcggat gttttctttc aatggattca tgacttggat atgattcttg attcttacaa
     1441 tcagtgcagc catgtgctta tagagatttt cgaataaagc ttcttccttt agatggaaag
     1501 gtacgtgtgt ctcgttctct acaaattgga tcaattggat cgttagtaat tgagcttgta
     1561 cccactcgat tgaattggag atatctctag cattgaacgt ctcaatagtg aaacgaagat
     1621 aatttctttc tacttgcggg acattgtcca attgaaattc ctcgatcatg tggtcaataa
     1681 atgcagaaaa gctactgtct tttatttctg tatttttcca attaatggca gagataaatt
     1741 catgtttcct gattcgctgg atccagatca atgtaaaaag caggatttgt tttttataaa
     1801 tatcatcttc ttgtttcaac aacttattgg aatagatctc ctgtattttt ttgatttcca
     1861 ccaaaggaaa ataatggaga aagatttttt gagccggtgt taattgtgca tcttgattca
     1921 taaagaagtc ggtcattccc agattctgat tgataaaatc atagatcatc gtacggatag
     1981 atcgttctga acctttataa accagtcctt gctttccata actgacgatc tctatcccat
     2041 aactgaccag tgttgctcgt aaccgtctca tatcttcatc taatgtactt ttagagattt
     2101 gaaattcttc ttcttttttg tttagatgga tcgggattcg gctgtaagca acggctaaaa
     2161 ctagatcaaa aatacgttcg cgccgattca aaaagccgtc tttcacatct tttatttcag
     2221 tttctaatcg agcttgcttt tccttttcca gcttcaacaa aaaacctttg ttgcgaattg
     2281 tacggatctc cggaagcttt ttactgctca accagatatt cgcttcaaga acttcctgac
     2341 ggatcgtccg ctgactgaca ttgaactcac ttgctagatg ttttgctttt actggatatt
     2401 gggctgtcat gattctgtga agtatttcaa ttgttcttgt tttcatagaa atgatctcct
     2461 tctgatttca agtatatggt tccgcttaca taataaaaag tagatatttc tgccacttga
     2521 agtggaaaga aagtaagcaa agcaaacaaa aaataagcca tatgcttttt catctcctca
     2581 acgaaaaaga catacgccta ttattacaaa aattttgccc atctatacaa aaaagaggtt
     2641 gtgaaaaagc tgtcctgcat caagtaataa gaacaactaa actaaaatag tgcttcctat
     2701 ttttcgtttg gttgttctta ttatcgcaga tgcaagcttt taaacaccat ttagtggaga
     2761 ggttgtgaca gagatgttca gccttgagcg ataagaagcg attttgaaaa atcgcttccc
     2821 atattttaca aaatcgtgcc ttattgccga taggctatct ctggcacacc gtttattcag
     2881 aaaaaggagc tgcgacaagg cttttgtcac aactccgttc ataaatattt cctgtcaatc
     2941 cagcataatc ggctgaataa aatcggcttg ccatcttttt tctttctcag aaaaatcaaa
     3001 ataccatatc tgagaaaaat actgtcgttg tgtcttactt cctgagatca atcgcccatc
     3061 ttttcgatcg actgaataat cacagcatct gaaatcaatt cggatggcaa aactattttc
     3121 gtggatctgt cgataatttc ctacttcctg aatagttatt tttttagtat gatttcttac
     3181 accgtctgct ttgttttttt gcagaacttt ctgatgttcg gcaaacagct tgtctgtata
     3241 acagcttctg gctttttcag gagtttcttc ttcccaagcg gattggatct tcatgaatat
     3301 cttttggatt tccagaaact gtgctttctt ttctttagcc gttcctgaca tgcgggacaa
     3361 tatctccgct ttcagccttt tcttttgtct tttattcttg acgatagaaa aagcagaaac
     3421 ccctcctact gacaaaacag ctaatgcaag aaatcccgtt tgctcataac tagaaggacc
     3481 tgtacctgga ccataatacc cataagaatc tctgccgtaa gaacgactgc caaaataact
     3541 gcccccatat gaacgaccac caaatgaacc tctgcccgaa cttcgaccgc tagatgtacc
     3601 tccaccatga ccacccgcga cagcgaatcc ttgggtcggc agagcaaaca aacataggcc
     3661 cactaacaaa atgattgcta aataattgat ttttttcatt gtcttcctcg ttatctttta
     3721 ttacaaaaaa ctatttttat gatagccttg ctaaaaggaa gagtcaataa ccagatgcat
     3781 aaactgtttt tttagcaatt ttgtcttatt tagtcattga gtaacatcgg acaaatgtat
     3841 gtgtcggcag tccataattc ctctatcttc agcatgaaca agcttgcaga caagagatct
     3901 gcgcttcctc caggagagat ttggttttcc tgacaaaagt gcaacagtgc tgtaaatgga
     3961 cgatttggta aagcactttg actagcagca tgagcaagtt tttgcatttc cactaacgtt
     4021 ttctgatcac tgcgatgcaa tacgcatgtg tcatctagcg aactcatcaa aactaacaac
     4081 atatgcattt gtttctgtac atatgaatca ttatctagct ccttagctgc ttgaattgca
     4141 agcctgatat gcggataccc taatatcgct tcttcatatg caccatttac gccatatttt
     4201 tgcttcaccc tatgaccatg agtggttttt ttatgacgat attttgtatc aggaaaagca
     4261 gcaagcttgc tgacatcatc aagtattttc gataaagaaa aaggctgttc catactgatt
     4321 ttttgtgcaa tgacactgat caatagcccc attgcccaaa tcgctccttt atgggtattg
     4381 atgccatttg tagcaatcag cattgccttt tccgcttttc gcccaatctc agcaattctt
     4441 tctcttaact cctgatcaat agcatgatgc catgctattt gagccatttc ttcaaaaaaa
     4501 ggagttagcg tcttagcaga cttaagaaat aaagcatagt ccatatcgga atgtgcaccc
     4561 gcatccagtg catccactaa tccaggtttt ggacttaatg ttacttctgc gatcaatgct
     4621 tcctctacca acgcagcgag ttgctgagtc actgcttttt ttcgttcgtc atttatcatg
     4681 acactcactc cttcttccta ctattacttg ctgaaacctt ttttgatagc tacccaaatg
     4741 atatgaagta accagcttaa agcaaatgca caacttgccg tcattagata agctacaaga
     4801 atcatgactc ctgaaggtaa ctgcagccaa ctatctttaa acaataataa cagtacttgg
     4861 aaaacaaata cattggctaa atacgtacga taagcataaa cagacaacca tttgaacaat
     4921 ggcaattttg gcgaatcgtt tacaatcatt ttggaagcgc ctatgaagac agcaaagatg
     4981 atgactaaac tgtataaact ttggatcgta ttcaagtaag gtgcattcgc aaagctcaag
     5041 tctcctggat gtgcgagcaa tgaacggaca gaaaagaacg cgataactaa ggcaacaggt
     5101 aagaaaagat aacgtactct gtccaaatat tgatagactt tttcgtgata aacaaatgcg
     5161 gctaccccat aaatcatgaa actagcaaca aaccgatcta ataagtacca gctgtcatga
     5221 taaggcccag tcaatacttg tgtttgatag aacagatacc atgcgacata taaaatcgtt
     5281 gaaccaatca atactggcca tacatatttt ttattagcaa atactttgta accgagccaa
     5341 acaaaaaacg gcatgaacaa ttggatctgc agcatcataa cggtatacca taaatgaggc
     5401 gctccatcac ctgtgacata tttcagtaaa aagcttgcag tatccgtata cggagtttgt
     5461 tgttggactg ctggaaatag ccaaagataa gccgtcgtcc atagaagata cggaacgact
     5521 agttcaaaaa acttttcttt caaaaattcc caataagaca aatgctgact tgtttttacc
     5581 atattataaa caattgcaaa aataaacatt ggtgctgtgt atttaacgat gacgtaaaag
     5641 gtaccaagaa aagctgtatt tgttgcgctg tggctgtttg ccaaagcaaa gctcaatatc
     5701 gtttgcatca taacagccgt tacagctgat actttctgga agtcacttac gttgattttg
     5761 atttttttgt tttcaaacat ctctttctct ctctttttct ttattaccaa agttctttgg
     5821 ttaatttagg tccttcgact gttttcaata gaattttttt ctctggctct ctcaaatact
     5881 cttttagtga aaaaccgcct tgccgagtca ctacttgggt atcgaattgc tcaaaaaaag
     5941 caggatgcga ttgaattacc tgaattggca attcaatcgg tgaatttgcg tacagcagca
     6001 aatcaaaatc actggtttct tttactgccg gaatcccagt cgataattca aatcctaagc
     6061 tgccgccgat tccccattta catcctgata atatgtttct agcagcatga aattgctgat
     6121 aaacaggata atccatgatt ttctcttgtc tatacgattc ttgttcgatg atgtcccacg
     6181 gatgaatgac ttgtttgacg gcatgttttg agatttctgt tgaccatctc tgattgcggg
     6241 caggtccacg taaaccaatc ggtagtattt ctgcgtgatc cgtcgacgca cgacgaactg
     6301 ttccgaacat cttttcagtt agaacgaccc attcaggcaa ggtgaaccct tctatttcat
     6361 gtttatcaaa aaggacaata tcatgtgctt gaatcatttt ttatgcatcc cattcttcgt
     6421 ccattttggc acggacttta tttgtttcga cacgtccgaa tgttttggct gtttcgtttg
     6481 tgtatcgatt tgtcagcatc gtgtcatttg tattgcggac atcttgaatg gcttcattga
     6541 ttgcttcgat gactttgctg acattttgtt ctgaagcagc ttggtcggtg atatcttcta
     6601 ggaaatgata gatcgctcct agttttgtat aattattgat atcgtaagcg atagctggaa
     6661 ctttttcagc agctgcttcg atttcagcaa ccgaacgttt tgtcacacgt gcagcacttt
     6721 ctttagacat cgcttggacg gtaatttctt tattgtttaa agcaatcaag cggcttgatt
     6781 gtaatccatg tgctaaaaat gcacctgaaa tagcatttcc tgcaatcaat ccaataactg
     6841 gatgtccagc ttgacggagt tttgcataag cagcagcact attagccaaa gccacatgga
     6901 taccgatcaa ttcttcgtta tagccgtatg cttggcttgg tacatcgatc acaacgatga
     6961 ttggccgttt cacttttttg tctttatctt cttcgtaaac gtgatccaaa atttgtccca
     7021 tgcggaaacc ttcaactaaa ccaacttcac cgtttcgtac acggtacatc gggtttttag
     7081 gatcaggtac gattgatgtc acgatggctt cttctatgaa tttacttgat ttaccataat
     7141 acacagtact aatagaagaa gttggatttt tcatgccagt tagtgccgca aaccaatcgt
     7201 aaccaacact tgctgcagct ggttcatttc cttctgctac ttctggtaag tcaattgatt
     7261 ttgcttgatg gttagcaatt gcttcattgt aatcgtcaat ggccattggt tttgaaagat
     7321 ctaaagaatc aagtaatgat aaataaaatg ctgagctttc actgcgatgc gtgtcttttc
     7381 gttcgtccat tgctgcgatg acagcagctt tgattgcttc tacactatca gtcactaatt
     7441 catcaatgat ttttgattct acccgttgac gagatcctaa tgtattccaa atcaagtctt
     7501 tgtcactaga atcaaattct cgaacgcctg cttcttgttc aataacttct ggtccattca
     7561 aaccgactct cgcttttttt gttgcgatta aataactcat taatgctgaa gtaatcgaca
     7621 taccgccaaa tgatcctaca cgtcctggaa tcaaaccgat gactggtaca tattgtttta
     7681 gagcaatgat tacatttccg atttctgaaa tagataacag tccgtagttt gcttcttgca
     7741 aacgaacacc acctgtatct agtacaatga ctggaaagat ctcatttcct tttttatttt
     7801 cttctaacac atgttcaagt gcagcaacga tttttgcacc ggaaacttca ccgataccgc
     7861 caccttggaa ttttccttcc atagcgatta ctactgcttg tttgccattg atcgtgccac
     7921 ggctgacaac gatcccgtca tcactttcag ggacgattcc ttgtgctggt aaacttggcg
     7981 cgatgatttg atcgaatgga tcaatcaatt cacgtccatt gtcaagtaga gcgttcactc
     8041 gttctctggc gtttaattct acaaaactat ttttcatctg aaagttcctc cattgcttgc
     8101 gtcaatcgta ggtacacaac tcctggtgta gcaccgaagt cattgatcac gatatctgct
     8161 gaaattggat aacgatcaaa aaatctcgtt aatacattgt tccatacttc gccgaagcca
     8221 tcgcttcctg tacaaatttt tacagtagat tctgtttttt ctgttggaaa catcaagatt
     8281 tccaaatctc ctgaaccgac cactcctaca tggattttct tattgatcgg ctgtttcgtt
     8341 ggatatttat aagctaattg ttccatggat ctctcccctt tttgtaaaac agagcataca
     8401 cgttctgctt attcgtcttt cttcttccat ctgggtaaat ggcgacaaaa ggtttttctc
     8461 gccaatttta tgaccaagtt ctgaatttca ttggtggttc atacaggcca tctgaccatt
     8521 cgatcaaatc atcgatggtt tgtgcagcta ataatgaacg tttcgcttca ctacgtttga
     8581 tgcctagatc ttctggtaat ttcacgatgc cggctgcacg caagctatct agtgattctt
     8641 tcgtgctagt cattccaaga ggtgtaacac cgccaattgc tgcaattgct gcttgtcgtt
     8701 cttcttttgt ttttgctttg tacaaataag caattccttc ttctgtcacg atatgtgtag
     8761 tatcttcgct ataaatcatc actggtgcat tggctaagcc tgcttgtttt tgaacagcta
     8821 gtgcatctaa ttcttcgaca aagactggtt ttttatttga accatatgtt tcaaccattt
     8881 gaacaactaa tttttggcct ttccctaatg gatcatcatt gtcgcgaagt gattgccatg
     8941 ctggtgtaga atgacgacga ccgccaggat tatgtcccat gttaggcgca ccgccaaaac
     9001 cagataaacg tccttttgtt acggtagaag agtttccttc gtaatctaat tgcaaggttg
     9061 aaccgataaa catatcgatg gcatattgtc ctgcagcttg tgataatgtt cggttactgc
     9121 gcatcgtgcc gtctttaccg acaaaaaaga catctgggcg agcagcaata tatttttcca
     9181 taccaacttc gccaccaaaa ctatggatgc tttcaaccca acctgattcg atggctggaa
     9241 tcatcgttgg atgtgggttc aatacccagt tcttcgcgat tttccctttt aaccctagtg
     9301 attcaccata agttggcagt aacaattcga tagctgctgt attgaatcca ataccgtgat
     9361 tcaaagattg tacgccgtgt tctgcgtaga ttcctttgat tgccatcatt gccattagaa
     9421 tttgcaattc tgtgatgttt tgaggatctc gtgtgaataa agcttctaat tgataaggtt
     9481 tatctgcttt cacgacaacg tctacccagt caccagggat atctacacgt ggtaaagaat
     9541 cgacaacttc gttaacttga acgatcacga taccatcttt gaaagctgca gcttcgatga
     9601 ttgttggtgt ttcttccgta ttgaaacctg tgtacaagtt gccgtcttta tctgctttat
     9661 ctgcagctac taaaacaaca tttggaatca aatcgatgaa taagcgtcca taaagttcca
     9721 aataagtatg gatatcacct aatttcattg tgccgtcttc aatcatttgg gcgacacgca
     9781 agctttgtgc accagcataa gagaaatcga tcttgcttgc gattcctttt tcaaaaatat
     9841 tcaaatgttc tggtcgtgag atactagaca tgatcaaatg cagatcattc actttttctg
     9901 catctacttt ttcaagactt tctgaaagaa aacttgcttg tttttgattg tcgccttcta
     9961 atacaacttt gtcgccggga gcaatcagtt tttccattac ttctacgatt ttttcagttt
    10021 ctacatactt gccattgagc aagttgctga ttttttccaa tcgctgcgct tttttttcgc
    10081 gtttagaagc ccagttgcgg tttggttttt ccataattag tcatctccat ttttgatata
    10141 gaaacgtggc gtcatcaata ccatgttggt ctagattgat cgtacggatc cctttatcta
    10201 caccaaattt tgtatgaatc agctttgtca aagtattgcc ggggggaaat tcaatcgtca
    10261 gatccattcc taattctttt gccaagtcca tcatttggtt ccactgcaca gggaaagcta
    10321 ggttttccaa caaatcttta cgaatctctt ctgcgtcctg agtggctctt ccatccgtat
    10381 tttttatata caaacatcta gcatcagata gatggacaga ctgcatatac ggcttgaatt
    10441 tcttgaccgt atcattcatc aagagacagt gagatggcac agggactttc agcagcttcg
    10501 ctgtttgcgc ttggtgccgt ttggcttctg ccaacgtaac ggataaacct tcgatactcc
    10561 cagataacgt atgttgcatc ggacaatttt catttgacag ataaactgga tggtcaggat
    10621 caaatgtttt tgctacaatt tcctcagctt cgcttctcgt cacacctact actacgccca
    10681 ttgcataacc gcttggataa gcttctttca ttaagactgc gcggtgatag actagttccg
    10741 ctgcattctc aaatctcaaa gatcgacaag caacagctgc acaaaaagca ccaatcgaat
    10801 gtcctgctgc aatatcaggc tgaataccgt ttttttccat ttcatctaaa taaaatactg
    10861 cttttgtcag taatgctagc tggataaaaa ccgtatcttg atagttttct tctttatcaa
    10921 ctaaccgata ccccgtcaca ttttctaaac gttccatgta catttcaggg atatccgcta
    10981 acatccctaa cttctgactg ccttgtccag gaaataagaa acctgtactc atgagcctcg
    11041 cctcctcagc acttactttt tccactgcta tcttagtcaa tttctgctat aataaaaaat
    11101 gccaaaaaaa gaaaaaacca taacaaaaag gtatggatgg gatggataat tatgaaattg
    11161 cttcatctgc agtattttaa aaaagtattc gaaacaaaaa atgttaccca agcagccaaa
    11221 gaattattta tttctcaacc tgccttgagc cgtgcgatca aacatttgga aaacgaatta
    11281 ggtgtccctt tgttttacca tagcggcaga aacattgaga cgaccgttta tgcagaagaa
    11341 ttttatccat atgcagtcaa gacattagac acattagaag aaggaatcaa attattgtct
    11401 tcggtcaatg agaagatcgt tacttccgtc atattgtatt tagaggtagc ctctgtttct
    11461 attccgaact tggtccgaat ttttatggaa aagcatcctg atatccaatt aacgatcatg
    11521 caacatcatt taccagatga tattaccgat cctgtactgt acatcacttc ggagatgaag
    11581 cctggcatga ccaatattcc tatcatgaaa gaacctgttt atgtcgccat tcctaagaaa
    11641 catcctcttg ctaaaaaaga acatctgcaa ttagaagata tccaacgcac ccccatcttg
    11701 atgctgtcaa agagcaacgc cttccgtcat acactggatg cagcacttga agcgaaaagt
    11761 atcgaattga cgatcagttc gacgacagat gatcctgcga cattacgttc tattgtcaag
    11821 caaggattag ctgttagctt tttcccaaaa gtttcttggt cttacgataa aaatgatcct
    11881 ttcgtcttgc gggaaatcaa agatttgccc ttgacacgaa caatttattt atcttctagc
    11941 ttcacagaag atcatccttt gatcaaaatg attgcaaaaa cgatgcggga attttattta
    12001 ggaaaataaa aaaaaaagag ctgggacaaa attcttgtcg cagctctttt ttcgaacaaa
    12061 cggtgttcca gaagtaattt cttagaaaat aagccgaaat ttcccaaaaa tttgagaagc
    12121 aattttcgta aattccttct tatttcttga agctaaacat ttctgtcaca acctcttctc
    12181 tattgtccta gacattcatt gcgttgattt aaaacttcca tcaatcaaat ctgctagttc
    12241 atctagcttt tctattttac gtagatcaat agagatccaa tgttctttat tcatgtgata
    12301 ggctggaaaa tacccctctt ttcctcgcaa aattccgcca agttcaggat cgaccttcaa
    12361 atcaagaata ttgatgatcc tatggtcact tgcatcatca tagatttttt cttctggaac
    12421 agacatcagg accccaaacc attttttgct tttttgatgt ctgaatacgc aataatcagg
    12481 aaatttttta aaaatatatt ctggagacaa attgtatgtt tcattgatgt gatcgattag
    12541 ttcttttttc gttagcatct gcttccatct ctttcttatt gattcgcttt attcaaagat
    12601 accacgtaag aatagaaaaa tgaatacaag tagttgctaa tcaaatactt cgatattttt
    12661 cttttttatc aactcttaaa tgttcaatcc gcctgtgttg gtcttgctac catctactat
    12721 taaaatgttt attattgttt gcccacctat tttttgattt tagtggtatc atttttcaag
    12781 ttcatgatga aattcttatc atcagtaaat gctccagaaa aataaacaat gattgaaaaa
    12841 tcagttgaaa cttgaccacc gtttattttc tccgtattct tagaatagaa gggagtctga
    12901 ttgatgtatt cactaatgaa aaaaatcatt accgaaaaag atattcgacg tcatgtttct
    12961 ttagtagaac aattgctgaa tcatacaaag ataaccgtaa atgaattagc tgaaatcata
    13021 gggacaaccg aacgaacgat tttttctgac cttcaatcta ttcgctctca gctgcccgaa
    13081 ggctgggaca tcatcagcga tcaagcagga atcagtttgc aaaaccagca aaatttatta
    13141 acaaatgacc tttgggagat ttttttcaaa caatcagtca gtgtcgaact gctgaaaaat
    13201 ctgcttttta caaaaaaagt tgctgtccct gattttctag ccgaccatgg gctttcttat
    13261 gggacattga aaagacatgt gactaaaatc aatcagcgtt tagcaagtta cgacttgcag
    13321 atcgatttga cgaaatatac agcttgtatt cttggaaaag agcgtgcgat tcgtactttt
    13381 tatcatcgat tgctgattcc tttcactcat aacaactatt ttttcgagga ttattcgatc
    13441 catgaatccc attattttca atttttaaga aacctcagtc aaactgaact agcggttgaa
    13501 acagaagaga ttttcggaac atgttggttc tttatcaata cgatccgtat aaaagcgaat
    13561 tgccgattag attcttctat ccataccaac agcacactct cctccctgta tgactctgca
    13621 ttgaaaaaat tgtatttaac ggaaggtatt tatcttaaag acactgagct ttcttttgct
    13681 tctttctgct ttctggaaag ttggaattac aacaataact atggacaaga aaccgctcgc
    13741 tgcctgcatc attctccatt tttagaggtc ctcgaaacgt ttgtagagga actagcttca
    13801 gagctgtctc ttgatcaact aaaaaaaaca tctctgactg ataacttggc tctcctcata
    13861 ttaaaatatc atgaatcgcc gatattgatt gaagcattgg accgtcaata ccatcgtttt
    13921 ttagaaacat atgatcagca atatgcacac ttgtatcaac agaaagagaa tttactgaac
    13981 gatctaaaaa aagaaataga aatcaatgaa ccaaattact ttctccaact cttgtctcta
    14041 ctgatccaac aaacgatttt ttctatcaaa ccgaatttgt tcaatgtcta ttttattttc
    14101 caaggagaac cttcatggaa ggcgttcttg cagcaggaat taaaagatta cttaggaaaa
    14161 cgtgtctgct tcttacctat cgaactaacc gatctttcca ctatttcttt tgaaaaaaca
    14221 gatatcttga tttccaattt ccctctagat tctctagata tccctattgt atacatttct
    14281 tctattccaa cgaaaaatga gctcaatcgt ttgactgaac tcactttcaa aactttttta
    14341 tagtaacggc tagcgactgt attctctagc tgttttttct tttttgcgaa acagtttgtt
    14401 catgatccct ttttctattt ctacaactaa gaatagaaga atcacatttg ctccaatcaa
    14461 taactgttgt gtcatcgtta aacttactgt accgatcagc tgctggccga ctggtagaaa
    14521 aataaccatc ccttgcaata aagcaaggat acctaatgaa agaaaaagcg ctttgttttg
    14581 caaaagacct tggttcaatg acggcttgga caactctctg caattgatca tgtaaacagc
    14641 ttgagctaag acgatatttt gcagaagaat ggtttgctgt aagctttgcc cttcaaactg
    14701 catagccaat aaataggcag gaaccatgat cagtagggag acatagatga tccgaaacaa
    14761 atgataacca gataggattc cttgctttgg atctcttggt gggcgcttca tgatttctgg
    14821 atctggcgac tcgaacccta gtgcataaga taaagtgatt gtcgttacca tattgaccca
    14881 taaaatctgt actggggaca aaggtagcgg gcgattcagc ataagtgccc aaatcaagat
    14941 caatccttga gctaatgcag ttggcaagaa gaaattgatg gttttttgca aattatccaa
    15001 aatccgccgg ccctctttta cggcttttgc aatcgtatgg aaattatcat ctcctaaaac
    15061 catatcagct gcctgtttgc ttacttcact acctttgatt cccatagcaa ttcctacatc
    15121 ggatcttttc aaagcaggtg catcatttac gccgtctccg gtcattccga cgatttctcc
    15181 atttttctgc aaagctttaa caattcgcag tttatgttct ggtgtcgttc gagcaaagac
    15241 atcgactatt ggcacttgct gaatcaactc ttcatcagac ataagatcca aatcgatccc
    15301 ttctaaaact ttggcagtat gttttaagcc aatttgttcc gcaatcgctt ttgctgtgtc
    15361 tttgtgatcc cctgtaatca ttttcactga gatccctgct tgttggcatt cctttacagc
    15421 tttgactgca ctttcttttg gcggatcgat caatccggcg atccctgcaa aagttaattg
    15481 ggttaaagtc tcatgcgtga gttcctgttt cgaatctact tttttataag caaatcctaa
    15541 aacacgctga ccttttctcg caaattctgc agctgtctga ctccatgctt cttgttctgc
    15601 agaagaaaga gttgatttag caaataatac ttctggtgca cctttgacgt aaatcaccgc
    15661 tcctttttcc tccgcatgca tcgttgccat atatttgtat tcagaactga acggaatctt
    15721 tgcttctatt tttttcaaag gtagattggc tgtttctgtg tgtcgaatca gcgcaacttc
    15781 tgtcggattg ccacttaaat tttctgtttt ctgttcttct tttgttttta attcctgaca
    15841 gtttttcata atggacaaca cgcaggcttc ttcttttgca gctacatcca caactgtcat
    15901 ttcatttttt gtcaatgttc ctgtcttatc tgaacagatc actgtcatag aacctaatgt
    15961 ttctaccgaa ggaagtcctt tgatgatcgc cttttctttt gccatttcat gtactccaac
    16021 ggatagaatc atggtcaaaa cagctggcaa tccttcgggt accattgaca ccaccaaagc
    16081 aatcgtagcc gaaagaagga tatgccaatc cataccatat cgaaatgtcg taaaaataac
    16141 taagaatagg ctcaaacaaa gaatgccttg aaaaatttgt ttgtttaatc ggttgatttt
    16201 tttaatcaga ggcgtcgttt gttgttcgac cgattgcaat gcttgattga ttttaccgat
    16261 ttctgtcgtg tttcctgttt ctacaacgac accgactgca gaaccagatt gtacaagcgt
    16321 tcctgaaaaa cccatatttt tctggtcgcc gatcgattct tcttctgtca aaacggcatg
    16381 acttttttca gatgcttctg attctcccgt caaaatcgat tcttccacta ataaatcatg
    16441 tgcttcgatt aatcggatat ctgctggaac gacatctccg gcacgtaaga caatgacatc
    16501 tccttttacc agttctttcg cagggatttt ttcttgcatc ccgtttgata gtactatcgc
    16561 ttcttgtccc atcagctgct tcaaaccatt caatgattct tccgcttttc tttcttgcca
    16621 gtaactaacg agtccattga cgatcactac gaataaaata atacttcctt caatatattc
    16681 actagaagca aatttcaaaa aagaggcaat gatcaacacg atcatcagca gatcagtaaa
    16741 atgctttgct atttttttcc atcgttttgt ctgctgcctt gcttttattt cattatatcc
    16801 ttgatcagtc aggcgtttct gtcgttcttc ttgcgacaag ccttctgttg atgtttgata
    16861 gtttttcaat acatcttcta ccgtcaatct gtaccagttc atcctatccc ctcctgttta
    16921 attgatactg ttattatacg cagggaagtt ttttcaggcg tatcgattat ttcagggggg
    16981 tctgaaataa ttcgttttgc aaaatgtatc tgggcctaac tgatatttct attgcttatt
    17041 cttttatata caaaatttaa gaatacaaac cagataacca ataaaaaagg aataaagcgt
    17101 gtcgtgcttt cgaataacaa gctgaaagca attgaagtaa aaaacaccaa caaagcaaga
    17161 tctttatatc tttgtgtagt gttccgtttc ttttctttaa taaattgaac atgtgcacac
    17221 aagatcgaag accacacaaa tagaaaacaa ctcgttgtca tgcctgccaa aagctgaaaa
    17281 aacaatcgac tatcagctac aaaaaaatgt agacaaagac cggcaaaaaa taacattcct
    17341 gtaattaaaa taccgtgtaa aggtacgcct ttcttagaaa gcgcacaaaa ccaatggggc
    17401 aaactttttt cttttgctgt ttgatataaa atcctgctag tactgtagac tgcactattt
    17461 gctgaggaca aagaagcaac caaaatcatt agattgacaa ttgctgctcc gccttggcaa
    17521 tggatcactt gcagcatagt cactaaagga ctttctttta aatctaaaca atgccatgga
    17581 acaacaaata aaatcgacaa aatcgttcct atatagaaaa agagaatacg ccaaggcaga
    17641 cagttgattg cttttttcaa attcttttgc ggatcacttg tctcgccaac ggttaagccg
    17701 atcatttcaa ttccagcaaa actgaataaa accataggaa atgagactac cattccagca
    17761 aagccaaacg gtagtaattc atcgatctgt ccaaaatttt ctttgattcc gatagactgg
    17821 gtatgaaaat ctgagacact caatcctata cccaataaga taaaaaggaa aatccccaag
    17881 atcttgatga ttgagaaaaa agattccaat tcaccaaacc acttgactgc aacaaggttg
    17941 actgccatta agatcattag tgcgctacct ccgcttatca aagctggtac atgtacaaac
    18001 cagaaatgga tatacaatcc tattgctgtt aattccgcaa gtccagctcc aagccagcaa
    18061 agccaataag tccaattgac aaaaaatgcc cactttttgc ctaaataata gtcaacgaaa
    18121 tcactgatag agttaaatgt actatttgct aaaaataaat cacccatggc ccgcatcaaa
    18181 ccataaatag ccaaaccgca tatcaaataa acgagaataa cagctggccc tgctgatgca
    18241 attgcctttg ctgaacctaa aaataatcct gttccaattg cgccacctaa tgcgattaac
    18301 tggatatttc gattagttag agtccgtttc attgccggtt tttccatcaa gttcaccttt
    18361 ttctttttca agcagcatgg cgacttcctg ttcccaagaa ggtttcttta ttttttcaat
    18421 acagagtggt actacaaaca aaatgacact gatggctgtg actgcaatta gattgatcca
    18481 tgttccagct ttcatcgtca gtccgacaga aaatccgatt gccgcaaata aaacaataac
    18541 gacagtccaa actccaagat tgctcttttt ctcttttttt ccaattctaa atggtcgatt
    18601 caactttgca tgtgtataac gcaatctcaa aactgcgatc cccatgatga catagacgat
    18661 acagtagata acagtagttg aatttacgag catcaaaaat gcttgattga cgccaggaat
    18721 cagcaaataa aaaagtgcaa agattgagat aatgacagac tgagtcaaaa taacggattt
    18781 ggatacgtca aattgattcg tcttccaaaa attgaatttt ggtggatacg caccttttct
    18841 agcactttct gtcactgtct ttgctggtcc tgaggcccaa gcagataatt ggactgctac
    18901 accaatgaag acaagtaaac taaacagatt cacaataaga tgtggcaaac caagaatttg
    18961 gcaataaatc gaaatagatt gcgcgatatt attcaattcc atttgtcctt ttggtacgac
    19021 atttgctaca actaaagcat tcaaaatatt gacgaaaaat ataaaaatta acgcggcaaa
    19081 tactccgcga atatacgttt taactggatt ttccaatcga gtgatataca cagaggacat
    19141 ttcgatacca gtaaaaataa acatgatcgg cgcaaaataa acaaatgagg atgcagtcgt
    19201 agtatctggt attaatttgt cccatgaaaa actgcctaat gttccggttg gtacgatccc
    19261 aactttgatc cacgcagcaa accctaataa gagcatcatc gtcaaaggca cgtacaatcc
    19321 taaccaaaca ccgacttttc cgccgatttt tgccatatca aatttcaaat tcaaaaaagt
    19381 gatgatccaa taaacgacta aaatgacaac taatgtaaat ttgctgttca aaccaagcgg
    19441 cacattatcg ataatattac caaacaacgg agcgagtgct gaagcgacca tcaccatccc
    19501 aggaaacatt tggacccata acagccatga gacaacgaac ccccattttt ttcctagagc
    19561 attcgatacc caaagttctg gaccaccttt ttggggaaac attccagcaa attcaccaga
    19621 gatcaatgag attggaaaag cgtacaataa tactgcaacc agcatgtaaa aaatcatcgt
    19681 ccagctcgtt gctgctacat ctggaatatt tcgtacactt gctacaaggg cgcaggtcat
    19741 tccgataaag gtcatggtcg tgatttgctt tgatgaacca gtatctttca tctttattcc
    19801 ttctttcaat agcgacatat gtttttgttt tcttttattt ttgttcaaga acagaaatga
    19861 caaggtttca tcgattcagt acaaaaccca gtatcaccga aacatccatt gaacgatctt
    19921 agtgaactgg gtttgataca tgaaacgaac gatccaactt atagaacgtt ttataaaaaa
    19981 gaatatcttg gcgaggaata tatgaaaaac agggggaaat acaattgttt tgatgaagca
    20041 aataattgtc tgttctccat atgtctcttg ttattctttc acacaaaaat cagttctatt
    20101 ggatgatttc gtttagtttc ttttccattg ctttggcgat tttttttgta taaaaattga
    20161 aaattcgatc atcattcaaa taaggagtca tgatagccgc acgtagcaga gtgattttct
    20221 gttctttttt ccattcttct ttcgttagac ccattctttc aacaaaacga atcggagaat
    20281 caccgtaatc ttcttgtgta aatgtagtat gagaagtaat aaaccgttca ccataaacat
    20341 cgccatccat ataagaagac cgatcgaaca ttttttcatt taattcattg atagcgttca
    20401 aatctgtaca gccttgttct ttgaataccc aattgaccat attaaaatca ggatgattca
    20461 atggatagac ttcgattgtt tttcctttaa cagtaaaagt cagatgatcg agaaattctc
    20521 tgaatctttg agctgcctcg attgaagccc caatcaattg accatatccg gtcacattca
    20581 atggcaatac acgatgtgct gtccagactg cggcggcggt tgctccagct tttgatcctt
    20641 ccaaaatata agctcctaac atatctggag cctttactga tttttcaaac acatatggcg
    20701 cgaaataaga aatgatattt ctcatatttt tatgtttgat tacgattcct ccagcagcat
    20761 aagggacata gcccatctta tgaggatcta tcgtgacaga atccgcttct gaaatagctc
    20821 tgaacccttc atatacctct ttgtcaatcg ttacgcagtg gtggaaaaca tgatgttctt
    20881 caaagaattc agctaaggaa gcatacggca caaattctcc tgcttcgttt agaaacagtg
    20941 aacgcgcata gccgccatat gcggcatcaa catgtaaata gaaatagatc ccttcatctt
    21001 ttaacctttc tcttaattgg acgattttat ctacactgtc tacttgacct tcttctgtcg
    21061 ttcctacgac agcaaccaca cctagaattg ggattttttg tccagctaat tcacgaattg
    21121 ttttttccaa agcattaata tccattcgat aatcctcttg aactgggata gcaaccatct
    21181 gatctaagcc gactccgcaa atatctaacg ccttcatcca agaatagtgt tttgtttgag
    21241 ggaccagcca tttccctaat ctttggatat tttttccgct acgggaagaa gctgctttga
    21301 cctcatccat ttcttcgtcc gtaaagcttt cggtcatttc caaaatttct tcaacagata
    21361 aattcaaaag ttcccactca gacatttttt tcactttttc aggcagcact tccttgacag
    21421 ctaaaggaat cgatttgatg caacgggcgt accataatcc ttcaagatta gcaatagaac
    21481 catctgctgc aatgtgtccc catccgtctg tcatattgaa taatgaagca aaatcctgtc
    21541 ctacttctgc ttccatttgc gaagttgcca tagaagattc caatgcaaca ttatttgggt
    21601 tccacagcat cgcatagttg taagctaata aagcaggcat caatgtttca gcattcattt
    21661 gtccccagta acggcctgct gaatgccatg ggatcgatcc tgcgcgtaat cgctgactga
    21721 cttcatccaa gacctctatc atatggtcgc gggtggctag ataatctgga gtgagcttat
    21781 ctccttcgct aattgcaggc atatctgaag gaatataatt ttctctccat ccaagatgtt
    21841 catctaccat cttgttcaac aacattttat aaactggtcc attttcagct ttgtcgccta
    21901 taaagacggc cttgatatcc atatctttca tttttcttcc ctccatattt tgttggtcaa
    21961 tgtcttgcag atacatgtgt ttatctgtaa cacctcttca ctatagcgcc aaaaatgaga
    22021 attttttttt tataacatca aatccacgta gatttttaca aacaaaaata aataaagtcg
    22081 gatttttctg ataattcaac gcaaaaaagc gaacaatttt tcaataaatc agtcttctaa
    22141 aatagataac ctaaaaaaag cgaacaaaca aataaaatga ctgtccttca ttcactaaac
    22201 atatttttat ttttttatat tgttaaaaat tcgcaattta ttttttaata gaattatctg
    22261 ttttccaaat tttataacat aaaaaacctt ttttaacggc atttatatgc tttttcagaa
    22321 attaactgat gatttcaaaa agaaaacatg tcataatatt tcccatattg tgcaaaaaaa
    22381 tacaaggcgg aggctctact atgattgaag aatatattga gaaaaatatt ttaagacagc
    22441 tgtttttatg tgggcaattc tatgtaaata aagaagtcaa tctagaaaag ctctccaatc
    22501 tcctgcatgt ttgcaaaacc actttactca atgatatcaa taacataaaa aaagaatttg
    22561 aagaacagat cgcttataca catcgggaaa aggaccgtta cactttatat ttttcagaac
    22621 atatacctcg atgcaagatc atgcagcaat tgtctcaaaa ttcgttgttt ttaaaaactt
    22681 gtctgcttta tttggaagaa gatgaacctg attatcttca attaactgaa tgtgaattca
    22741 tctctgtcag caaagcttat tcattaaaaa aacaagtatt agcttatttt aatgactgcg
    22801 ggatcgaaat cgaccgctac tcccctcgat tcactgaaat ggaaagacgt ctgctgcttc
    22861 ttaatgtgtc gtatcgttta ggcggtttta attcttggga gctacctgaa tcgttttttg
    22921 aacgtgccga tcgtttcatt gaatccgtaa cggaaaatag tggcagattt tatgataaag
    22981 aaaataaaga aatcttatcg attggttttg ctatcagttt cctacgccag caagtgtgtg
    23041 ctgtgacaat agattcaaaa tttatcgaag aaatcaaaaa acgtcctatt tacaattatg
    23101 tcgaatcagc atgggaaaac actgatttcc aaacctatta taaaaaagaa gaattcgcct
    23161 ttattttgac actattcaat ctttgtaatt atggtttcca ttcttatcag ttgattgcgg
    23221 aagactttca acagctacac caagtgttta ttgacaatac tcccgaaata aaagaactag
    23281 ttgctacctt tgaatctcac ttcaatcaag aattattcgg aaaccaaccg ttcgaacgtg
    23341 cgctgattca tctgatgcgt tcggcttggg ataactatca attattcatg ccagaaaaat
    23401 tttatctttt aaatgaggaa cagacaaatt tatataaaga agtccagaca attttttcca
    23461 gctggtccag ccagttacct tatgatctac ggttgaatcc taattgcatg cgggcttttg
    23521 tgatcgaatt gagcggaatt ctccgtctga caaaagaaca tctgactatc tatatcgtca
    23581 caaattcgga tgttcattat ctgatttatc gggaagcctt ggaagctgta actactttcg
    23641 attttcaagt tgcaccaaca atttattcaa gtatatctga tataaagaag tatgcgcagc
    23701 agtcctcaaa ccgggtatta tgtgaacgta cattatatac accagatgcg gtccaatatg
    23761 aaaatattat tcctatttcg atcaatacga tcgatcgagc tatcatttca gctgtgcaaa
    23821 acaaataagg ggctgtgaca aaaatcatgt cacagcctct tatttgttga agatgcccat
    23881 ttctgtaaca atctcttgat acacgtcagg ctcacaacct cacttatttt ggacatctac
    23941 gggtccgatc tctttattta aaaaataaga aatgatggtt cggataacta ccaacgccgc
    24001 tagttggaaa atatcctgca aggtaggttt gataatcgat tcgatgatcc cagctgaaac
    24061 aagaatttcc aaacttagaa gtatatagcc tcccaacatc tttttaatag cattgttctc
    24121 gctgactcgg tcgctttgca cttttgtatg gacaaataaa tatttcaaaa aatccttgat
    24181 tgatagacaa acaccccaaa ccaataaaca gatagcaaag atatcaagtc ccagtacaag
    24241 tttttcgaaa tatggaagaa gaaactgcat caactctgtc gtcatcctac ctctcctctt
    24301 ctttgttttt ctttgtcttc tatttcctga ttcaagaaat aagaaatgac tgttcgaatg
    24361 ataataataa gtgcaagctt caaaatatct gtccaagtcg gcttgataac tgactcgatg
    24421 atatcagcaa cgactagtac ttccaagctt aacaaaatat aacttgctag cagttttctt
    24481 gtatctgcat tacgagtatt acgttctgca tagtttttct tgacatgaga ccaatcaaaa
    24541 agtttgaata gaacaagaac gatcccgaca attaagatac cgatagaaca aatatttaaa
    24601 atagcaatga tccattctag aaattcaatt aaatttgagc gaaacatata cgctacctac
    24661 tttcttttaa tttgttccta ttcttttatt gtaaaagaaa gttaccttgt tcgtctattt
    24721 aaaagttgtt ctaatgataa cggttcgctt aaatttttct ttttcactct cccatttttc
    24781 tccctccatc cataaatcgt ggaagtatcc aaaacaacgt agcaagttaa aataaggctt
    24841 agtccgtcat cagcttttca aagaagcact gtctcggtgc tttttttgta cccaaatttc
    24901 taaaaataga accatacacc tcctcaaatc ttttcttctt acctacccta tttttattta
    24961 caggaaaatc agacacttct tcttttttgt caaaatttcc tttttcttct cgtcctatca
    25021 tttggcattc taataaaaac gaactatcct tggatataga aagagaaaac aaggaggcgt
    25081 ttttcatgag taaaaaatta atcaaagtcg gcatcggttt aggtttgctt gcccttggcg
    25141 ctgcatatct aggaaaaaag acaggactat tcgaagatga cagtcattta tatgatgaat
    25201 tcgaatcaat ctagcatcct atttagttga atcactacgg acatacttgg aagacattgg
    25261 aggaatcaca atgagaaaaa gtaaagcaat aatgattggt gccggtattg ccaatatggc
    25321 agcggctgtt tatttgattc aagaaggcaa atggaaaggg gatcagatca ccttttattc
    25381 attggatgat cacggttcaa atgatggtgc accgaccgac actgtagtgg atgaatattg
    25441 gaataaaaac catccattag aaaaccaaaa aggctatatt gctcgaggcg gtcgcatgct
    25501 taattaccgt acctatgtag atttgatgga tctgttaagt cgaatacctt ctgttactga
    25561 gccagggatg actgctgaag aagatacgag agattttgat gcaaaacacc gaacctttga
    25621 caaagcacgt ttgatggaag gtggcaaagg aatcattgat ggcggaaaac tgggattcaa
    25681 taataaagac cgtattcttc tgactaaact gattgctatg cctgattcag aagaagaaaa
    25741 actagacaat atcactatcg aagaatattt caaagatgat ccacactttt ttgaaacaaa
    25801 cttctggttt atgtgggaaa caacatttgc tttcagaaca cgtagttctg ctcaagaatt
    25861 gcgtcgctat atgcatcaaa tgatttatga attcactcaa atcgaacatc tagtgggcgt
    25921 caatcgaaca cgttacaatc aatacgaaag tattatgctt cctttgatcg agtacttgaa
    25981 agaacaagga tgcaaaatca ttttgaaccg ccgtgtcact gactgggaat tcaaagaaac
    26041 accgatgcaa gatgaaatca ctgtgactgg tttgaaaatt accaatacac tgactcaaga
    26101 agaagaatac gttgtggtcg atgaagatac agcagttatt ttcactaatg ggtccattac
    26161 agattcagct actttaggag attacgaaac accagctgta gaaaatatgg attatggtgc
    26221 agcttctagt ctctggaaaa aagccagtga acgtttctac aacttgggaa atcctgacaa
    26281 attctttgct gatcgagatg caagcgaatg ggtcagcttt accctgacga cgaaaaacca
    26341 tttgttgttg aatgaaatca cccgtatcac gactcaagaa ccaggaaatg ccttgaattc
    26401 atttatttca accacaccga tcacgccgtt aggccaaaaa gatgtcaata tgtctattgt
    26461 cgtgcatcat caaccgcatt ttacgtctca gaaaccaaat gaaacagtta tttggggtta
    26521 tttcctttat ccaagacgac gtggcgaatt tgtggataaa cagtatatta aaatgaatgg
    26581 aaaagaaatg ctagaagaac tgattggaca actttcaaaa gtagatcctg gaccagtgaa
    26641 tattcgtgaa aaagaaacag aaattttcga cagcgtaata aataatatcc ctgtctatat
    26701 gccttatgct tccgcgttgt tcaataatcg tgccaaaagc gatcgaccaa aagtcattcc
    26761 taaacattcg accaatctgg cctttacagg agaatttgtc gagcagcctt atcagatgat
    26821 ctttactgaa caaagtgctg tacgttctgg agaaatcgct gctttccatt ttgcgggtat
    26881 tcctatgtcc cgtcttgtca aaacaccgcg ttacgacaaa gatattccta ctctagctcg
    26941 tgccgcaaaa aaaatgtttg aataatcaag aggttgtgaa aaagctgccc tgcatcaagt
    27001 aataagaaca accaggctaa aacagcttct tatgtttttg atttggttgg acttattacc
    27061 gcagatgcaa gcttttgaac accgtttacc aagaggttat gaaaaagctg ccctgcatca
    27121 agtaataaga gcagccaagc taaaacagct tcttatgttt ttgacttggt tagacttatt
    27181 accgcagatg caagcttttg aacaccgttt accaagaggt tatgaaaaag gcgtttagtt
    27241 tcgagtatga agaaaaattt tgtgaaaatg gttcctcacg tttttgcata aatttgactt
    27301 aataccgaga aactgatccc ttctgtcata acctcttttt atttatgtct gtttcttttt
    27361 gaaaacaact attttttcaa cgtttactct cttgccaatc caacatcatc taacggatac
    27421 aactatttca atgattacca ttacactaaa aaatcggaaa cacacctctc cgaacacaaa
    27481 tacataagac tatagaatgt ttcatttaag aaaaaaagcg tttcattatc aaaaaggtaa
    27541 gatctccttt aaaatgaaat tatctgtagt actaataatg cagacaattt tatgaatctg
    27601 aaaggagcat ctccaatgaa agcagtcact tggcaaggaa aacagaaaat ggaaatcaga
    27661 aacgtagatg atccaaaaat attagaacca acagatgcaa tcatccgtat cacagcaaca
    27721 gccatttgcg gctccgatct gcatctttac catcatggtg aagcagtttt ggaaaaaggg
    27781 tatgttgtag gacacgaacc aatgggaatc gttgaagaag tgggatctca agttcaaaca
    27841 ttgaaaaaag ggcaacgtgt ggttatccct tttaatatta gttgtggtca ttgtcatttc
    27901 tgcctgaatc acatggaaag ccaatgtgat gaatcaaatc cagatcagtt atatggcggg
    27961 cttttcggat ttggcaagtt gaacggtaat cattggggtg gtcaagcgga atatctaaga
    28021 gttccttatg cagactctac ttcatttgtt gtaccagata atgatcttcc tgatgaaaaa
    28081 gttttatttc tatcagatat tttgcccaca gcttattgga gcgttgaaaa cgcaggagta
    28141 aaaaaaggcg atacagttgt gattctaggt tctggtccag tcggtctatt cgctcaaaaa
    28201 ttcgctgtta tggctggagc agagcgcgta atcgcagtag atccagtaca gcaccgtcta
    28261 gataaagcgg ctaattacaa tggggttgaa acttatttct tagaagacac ggcacaagct
    28321 ggaacagaat tgtatgaact ggctaaaggt ggcgcagatg tcattatcga ttgtgtagga
    28381 atggacggat tagagcctgt caaagaaaaa gcgaaaaatt tagtaagctt acaaagcggc
    28441 acaatctctc cattacagat ggcatcgcaa gctgtcaaaa aatttggaac agtccaagta
    28501 actggtgttt atatgactcc agcttcttct tacccgctgc aagaattttt tatgcgggat
    28561 atcgctgtca agcatggaca ggcaccaatt atccatctaa tgccaaaaat ttacgcaatg
    28621 attgcagaag gactattcga tcctacacaa atcattactc attcgctgcc actatcagaa
    28681 gcagcacaag catatgagat ctttgacaaa aaagaagata aaaatataaa agttgttttg
    28741 aaaccttgaa ttcagtaaaa aatacaggtg attttcttta tgcccaaaat caaacgaaat
    28801 acccatgaga tcgaaatagg aaaagaagaa gatatcgaaa tacgaggacg tcgcttccgc
    28861 ttctatttcc aaaatcgtta cacattgatc tcactggctg tcgatttatt aaccgggatt
    28921 ttctatattt ttggaagcct tgcttcctta actaaaatcc ccgatcgata tggcacctat
    28981 ttttatttgg ctggtgctat tttcttgacg attcgtccta ttctcagaat cgtaaggaac
    29041 atttttattt acgacgaaaa aaaagcaatg aagagaacaa gcaaaaaaaa agaggcatga
    29101 gaatttttca aatctcatgc ctcttttttc accctatcgt atcactttga tacagacgag
    29161 cggtcgtccc actttcttcc ttgaccattg tcaaaaatgt ccactcgtat cgttcataaa
    29221 acgtggtatg atctgtaatt aagtaaagtt tttcgtaccc aagttgatgc atttcttttc
    29281 tgatttccgc taatatccgc ttggctatcc cctgcttacg cttttccggt tcaacaaaca
    29341 gggcacaaag atttggtgtc agatcagggc ggttatggaa gtcgttttca atgacgcccg
    29401 ctcctccgac gatggtttct ttttcatcta agaccacata ccattgagga atactttcct
    29461 tattagcgat tccagtacga atactttcct catacacaac agcaggaact ccccattttg
    29521 atgaaaacca attcgcgctt tgttttacta attctgggtg ttctcttaat ttgatccagt
    29581 tatatgtaac caatgtttaa acctccgact aaaataaaac gtttacaaaa attatacaag
    29641 tctttatgaa aattagcaat gacaacaata gtgatgtaaa aaaaaaaacg gaaaacaatc
    29701 acttgttctc cgttttttga ttaatcaagc atctaaagct tcttttcttc tttcttggat
    29761 cgtagctacc ttgacgaacg gtagatagat caaaatagaa agaaccaaat tgacagcggc
    29821 tagtacacca cctgcaatac tttttgttgc caatacaccg ccaataattg gtggagttac
    29881 ccatggaggc ataacggtag ctgctggcac taaacctgta gaagtcgcaa agtaagcaac
    29941 actaactaag accattggtg tcaaaataaa tggaatgaac atgatcgggt tcaacacgat
    30001 aggtaaccca aacatcgttg gttcattaat attgaagaca cctggcgcaa tcgacaagtt
    30061 tgttacaacc atatatggtt tgtttttacg tcctactaaa taaatagcta acagtaaacc
    30121 taaagttgca cctgttcctc ctaagttgac aaagctgtca aagaaaggtt tgttcacgat
    30181 aaacggtgcg ctatgtccag ctgcgattgc attaacgttt gcttcaatgg ctggcgcatt
    30241 gattgtttgc atcaaaggat cgaccatatt cgctccgtgt aaaccaaaga accataagaa
    30301 tggtgtgata aatgcaagca gtaaggcaga tggataagag tttgcaagtc ccataaatgg
    30361 ttcttggacc actgtataga aagaacctac gatatcatca acaccgaatg cagcaaaaat
    30421 tgcagcaact aaagcaaacg cagagatagt gatcattgct ggtagtaatg aagcaaatgc
    30481 ttttgcaact gccggtggca caccatcagg cattttgatg atcaattttt catttccgct
    30541 taaacgtaca aagatttctg ttgaaataat cccaacaata atagcaataa acaaaccgtt
    30601 tgagctcata cctaatgctc cgcctaaagc gaagaaagag cctaaagaaa tcacacctgc
    30661 ggaaacaccg tcttttcggt agccgttagc taaatgataa gcaagcaaga aagcaatcaa
    30721 gacagaaaga atggcaaatg taccgttcca agcagcagcc ccgaatcctt tccatgattc
    30781 accaccaaaa attgagttca tcaattcttg gaacccggga atcggtaagt tattgatcat
    30841 tactgctaat gctcctaaga tcattaacgg catactcacc ataaatgagt cccgaatcgc
    30901 aactaaatgc cgttgtgcac caatttttga tgctacaggt ataaaatgtt tctccataaa
    30961 tgcaacaaat ttatccataa atcttccctc ttttctttac tgtagattac gcgttcaatc
    31021 gacgatacag atcaatgatc tcttttgcta aatctgtaaa agctatagat gtcatcagat
    31081 gatcttgact gtggaccgtc aaaagcgtga cttcaacgtg atttccttgt gcttcttgtg
    31141 tcagcatctc tgtttgagag tgatgtgctt ggactaaaga ttcctctgca tctttgattt
    31201 tttcatctgc taaagtgaaa tcaccttttt tcgcagcagc aatcgcttcc attgcatcgc
    31261 tttttgcatt tccgccaaac atgatcagac ccatgatggc ttctagattt ttttgatctt
    31321 ccatttattg tatcctccga taatttttat tatttgttta ttagtttttc tgcttggtcg
    31381 agtacttttt caccattcat catgccatag tcagccatat tgattacatc taaaggaatg
    31441 cctttaggtg ctagcttttc agcaaattga ttttgcataa agcgtacttg cggtcctaaa
    31501 agtaaaacgt ctacattttt agattctagt tgattatccg catctgaagc agatacagca
    31561 aagatgtctg cttccattcc ttttgcttct gctgcctttt gcatttttgt gactaggaga
    31621 cttgtactca ttccagctga acatacaagc atgattgttt tcttttccat tttaaacacg
    31681 ttcctttcta tacttacact tgtatataag caagtagcgt gccaacttta aaagcgcttt
    31741 aaaaagttga tatcatcaca tttaaggtct ataccaagtt gcatacacac taaaaaagaa
    31801 agcgcacact aaacacacaa attaattttt attacctttt ttcttttaac gtgcacaaaa
    31861 aaagttgtga cacaaaactt gtcacaactt ttttcaaata aacggtattc aaaagcttgc
    31921 atctgcggta ataagtccaa ccaagttaaa aacataagat gttgttttta ctttgctatt
    31981 cttattactt gatgcaggac agctttttca caacctctca ataaacggtg ttcaatcagc
    32041 tgaccctggg tattagctca aaacgctgga ttcacaacct cttttatttc aaataaccag
    32101 taaatacaat gaacatctac aaaaaacttc tatttattta tagatttcgt caggcaaatc
    32161 caattctctc ttatcaatca aagtctgata ccacgaagca gattttttca atgttctgct
    32221 tcgttcatcg ttcaattcga ttcgaactaa tccatatcga ttcttaaatg cattcattgg
    32281 tgacacacag tcagtgaatg cccataacat atagccttcg caatttgcgc cttcttctgt
    32341 tgctttgatc aagtaatgca aatgctgtcc gataaattcg atacggtaat catcttgcac
    32401 gattcctttc tcatccatat actgttcttc atattctctt cccataccgt tttctgttat
    32461 cagccaaggg atattatgat aattttcttt tagatacatg gctatatcat acatgatttt
    32521 cggatagatt tcccatcccc tggaattatt cattttcttc ccaggtaaat caaagacttc
    32581 ataatatcgt tcaggatgga aaggtgtctc ttcattccat tgataacgag gggcgcgaac
    32641 gcgtttagga taatattgat tgattccaag gaaatctact gtatgatgct gaatcgtttc
    32701 taaatcctct gttgcaggat cgaaataaat cgattgtttt tgacacaact ccaggaactc
    32761 ttctgtgtag tatcctttta ccatcggatc aaaaaatact cgattataaa acaaatcata
    32821 catataagca gctttttggt cttctggaga attggatcga gcatagacca tttcaggatt
    32881 taaaatacag ccaatccttc caccataatt tccgctgcgg taaatctcta ctgctttagc
    32941 cgttgctaaa actttatgat aattccacat catccacttt tttgtgtttt gttcatgcgg
    33001 ccagcgaaca gcatccaaat agcaacgcgt ttggggaacg attggttcgt tgaatgtaaa
    33061 ccagtttttt accctatcac cgtaacgatc aaaggcaatt tgagcatact tagcataaaa
    33121 atcaactact tttcttgaag accagccatc atatttttcc aaaagaaaag ctgggacttc
    33181 ataatgttcc aaacaaatca tcggttctac gtctgcttcg atcaaagagt cgatcatttc
    33241 acttatatgc tgagcatatt cttcatctac tatacagttc tcataatcag taaaaaaacg
    33301 agcccaattg atagaagtcc gataatgtgt cagatggatg gatttcatca gatccacatc
    33361 ctgctggtat tgttccataa aattagttgc tacggctggg ccatacccat tatgccaaac
    33421 aaaatgttca tttttatacc agctatctat aaacgaatcc tgtccttctt tttttccttt
    33481 ccaaccttcc gtttgccaag cagaagatgc agcaccaaga ataaaatttt ttggaatagt
    33541 aattttcatg atttcctcct gttttttaga tcccatcatt ttccacacga tttgctactt
    33601 ttacaaatgg cagatagatc aaaatagaaa caataataca aacaagttgc gtaataactg
    33661 caccgatatt tcctgctgtt gccagataag cattgacgat cggcggcatt ggccaaggga
    33721 ccattacaac tgctttcgcc gcaaatccta aagcggttgc aaaataacca atcgttccag
    33781 tgataagagg cgttaagata aacggaatag ctaaaattgg attcagcatg atcggcatac
    33841 caaaaataac tggttcattg atgttgaaga tcccaggagc aagggataac ttggtgattt
    33901 gtttcatatc ttcccgtttt ccaactaaca atactgcaat cagtaaaccg atcgtgactc
    33961 cagacccgcc catactcata tacatatccc aaaatggcat agtaataatg ttcggtactt
    34021 cttttccagc ttcaaaagct tccgtattta cagcaattgc cgctaaaagc aacggttccc
    34081 gtatcggctt caccatttga tttccatgga taccaatcac ccaaaagact tgcgcaataa
    34141 acatcaatag caaaataccc ggtaaccctt gtacgacacc ttctaatggg cgttgtacga
    34201 cattgtaaat gatatcataa aggtacattc ctgtaagttc tttgatgata aatcccgcag
    34261 ccgcgatacc cgatacagtc agaatcgtcg ggaataaagc agaaaaacta gcagaaacat
    34321 tcgttggcac ggtatcaggc attctcagct gtagtttctt ctgtttcctc aaccagcaat
    34381 aaagttcaat agaaaggatg gagaccaaca ttcccaaaaa taaccctttc gtatctgtat
    34441 attgtttagc caatacgttt tctactataa cagtctgatt ttcattcact aattcataaa
    34501 cagttggatt aacagataaa taagacatca ctgcgatgat accagggaat acaccatcca
    34561 ctttattcag cttggctaat tcgatcccta tcagaaaaac agcatagatg gtcaagaaac
    34621 ttagtgtgac atagctgatg gcagatgcga taggctttaa ttcttctaaa aaacgcaaga
    34681 aacttatctg tgctaagcca ttttccgagt caaagaccat tgctgaaaac aatgtgccaa
    34741 aagcacccgt aataattacc ggaatcaatg cagcaaatgc gttttttatc accatgatat
    34801 accttaaatt attgattctc gttgccacgt tccctaaaac attggctaat ttatccataa
    34861 aactcattcc agatcccctc attcctgctt cttctccttg acgtcatctc tttttgtcta
    34921 ttagtcagcg cttacatttc gatgaacaga aactatttac tcctcttttt taccaaatat
    34981 aaaacaaaaa ttcatctgat gtatttatca taaaatacat cagatgaact gtcaattagt
    35041 ttctttttct cctattattt tctgtaattc tctccgattt attgccatat ggacagtcat
    35101 tgcatcaaac gcagcaagtg cattccgcct ttcgatggcc tgaacgatct ctgtatgaat
    35161 atcgatcgtc tcgattttca gatgctggat atcataattt ttattaaaca aagcaattga
    35221 ttcattaatg attgggataa tatgcagcaa ggctacgttt ccgctagctt ctgcaatcat
    35281 cgtatgaaaa tcgatgtcta attgaacatg ttcttgtgtg ccttctcgaa aagaagtttc
    35341 aatcttttgc gttaattttt tcatttggac gatttgattc ttcgttgcat attccgctgc
    35401 caaacctgcc atcttaggct ccaataaata tctcagttca aataagtctc gtatcatccg
    35461 atcctgatct tcaatcaaag aaaaaccgag tgggtcattg gcaatccctc gcttatcact
    35521 gacaaatgtc cccgctcctt gccgaacttc aaggatattc ctggaagcta gagcccgcac
    35581 agcttctcgc accgtgcttc gccccacctc taaataatcg gacaattcat attcattcgg
    35641 cagtttatct cctacttgca actgcatttc ctttaaatat ctaaggatct tgtcagtagt
    35701 tacttctact agggttttat tttcttccaa accacatacc tccttttcat ctgatgtatt
    35761 ttttcgtaat tattataaca cgtttgaatc atctgatgat tttttgtata caaaattgat
    35821 taatccgttc atagacatac aaacgaagaa gatatttacc ataaaaaaga ctaggataaa
    35881 attcactcct agccttcgat catttttatt ttgaacgaca aaaaatatga tgttcaataa
    35941 cagacgatct tcattcgatt cttgatgtca tcttttgttt tttttaatat atggataaaa
    36001 agtttgatta catcgtttct attctagaat ttggtcgatt ctcaattctt cttctggtga
    36061 gaaatctaaa ttatccatca ttcgaacact ttcttgtaac tgacttaacc gacttgctcc
    36121 gaccagtaca cttgtaacag atttttgtcg caaattccat gcaagggcca tttgcgctaa
    36181 tgattgtcct cgtgatacgg cgattgtttg cagtgctttg attttttcca gagttgatcc
    36241 aacttgttct tctgaaagga atggtatttc cttacgatgt gctctagaat cttcaggaat
    36301 accatgtaga taacgatttg tcagcaaccc ttgagcaagc ggactgaacg tgattgcccc
    36361 tagcccttct tcttctaata ctggagatag atcgtcttct agtagtgcac gagaaaacat
    36421 attgtagcgc atctgatgaa taatgaacgg tgcttccttt ctttttaaaa tttcagtcat
    36481 tttttttgta tcttctccat tatagttgga tataccaata tataatgctt ttccttgtct
    36541 tacaagttgc atcaaagctt ctgctgtttc ttccaaaggt gtatcagggt ctgggcgatg
    36601 atgatagaag atgtcaacat aatctagccc cattctttgg agactttggt cacaacttga
    36661 aatgatggat ttacgagagc cccattcccc atatggccct tcccacatat gataacctgc
    36721 tttgctagaa ataatcagtt catcacggta ggcttgaaaa tcttctctaa aaatacgccc
    36781 aaagtttttc tctgcagctc cagcagggcc tccataatta ttcgcaaggt cgaaatgggt
    36841 aattcccatg tcgaatgcgc ctcttaaaat ctctctttga ttatggatag gatcataatc
    36901 accaaaattt tgccataatc cgagagataa aatcggtaat ttcaaacctg aatgaccgga
    36961 tttacgatat tccatttttt cataacgtgc actatctgca atatacaatt tttctcctcc
    37021 tcatcaaatc tttttaaaac gctttctttt ttctattttt agtttactac attttaaaga
    37081 aaaggagtta atcaaaatga ttttttcgta tatttttttg ccatttgttt tttactcgtt
    37141 gatagatcag aaattgatta cgtgcttgct ggattttttt ataacgtttc ggttgttttt
    37201 tgtaaaattg ctgatgatag ttttctgctg gccaaaacgt accggctggt tcgatttttg
    37261 tgacgattgg ttggtggaaa gttcctgaac tgtctagttt ctgttttgat tgttccgcta
    37321 attctttttg tcgttcgact tgataaaaaa tcactggacg atattgcttc cctctatctt
    37381 gaaattgtcc aaatgtatct gtgggatcag taatttgcca atagattgtc agcaactcgc
    37441 tataacttat ttctcttgtg tcataaatga tctccacagc ttccacatga cctgtgtaac
    37501 caccacttac ttgatcataa tttggttttt caacatgtcc gcccgtgtat cctgacaaaa
    37561 cagataggat cccttttttc gattcaaacg gctcgaccat acaccagaaa catccccctg
    37621 caaatactgc acgttcttga tagtcagcat cttgcatggc atgcttggaa aagtcatatt
    37681 tttgctcctt atcaaatcct tccgtaatca ataaataaaa gtccattaca tcaggcgtca
    37741 gattcattcg gatagctaat ggacgtagtg ttgcttctag ttttgataac tgttctttaa
    37801 cggatatatt ttctcttatg tcattctttg tctgaatcaa tacttttcgt tcccaatctc
    37861 gtgtattcgg attcaaaatc agattataaa gtgtttgaat gaatatttgt tcctcatcca
    37921 tagattctcc tcctttccga agaagacaag ctagtgactt tagctgtaat ttatcataaa
    37981 gtgaggaaat aagcgattac ttcatccccc tacagatttt tcgtataaaa aagagagaat
    38041 ccttatcgac agattctcct ttttaatcaa tttattttat aaatgaaaag ttaatttacc
    38101 ttttatggaa aactatttta aaaaataaac ataaatatgc agttaatgta acaagataag
    38161 aaataatagt cgttactgta taacttgtgc ttactttaat atcagcaact cctttgactc
    38221 cgcttatttg taccaatcca ttagcattca cctgctcctt tacaggttga tgatttattt
    38281 ctacattcgt tcctaaataa gcatatacag gaagtgtgat tacttggctc ttctcattag
    38341 ttactctata tatgatagaa ctaccagttg ttttataagg aaggtttacc cattgactgc
    38401 caatctttgc ttcgtgtttt attatatgct ccttattctc caatgaagcg ataggagaat
    38461 aatcatataa aaaataatcc attcctttag tggtatacgc ctctactgtt tctttgttta
    38521 caacaatatg tcccggctga gaaattattt tttgattgaa atttttttta ctagaaacag
    38581 ttaaagtgat taataacaaa acagtcataa ataaataaaa tagttctctt gtcttattgt
    38641 atcttctatt tttgaaaaat atcatcgtta atatcagaga agagaatatt atttgcaagc
    38701 ttaagatccg ccaaggaaat tgtaacaatt tggctggcgt attttgcaga agataccatg
    38761 gcaccaaact agttgtagct agccaagtca aacacgtacc ataataaatc tttttttcta
    38821 tgtttgttaa ttttttaaat aaaatcaggg gaatacataa agataacaga ccaactagtc
    38881 ccattgagta agtagttaag tcgttgttca tagcttcagt cagactatcg aacacattag
    38941 atgcatgagc atataaattt gtcacgctag gtttgttgat tttttggtag agcatttgtt
    39001 caaacatcgg ataccaaaaa gcactcgtca gaaccaatgt cattcctgcc gcactaaata
    39061 attttttaaa tatagcaata aaatctgcat tcttgaaacc tttagaaacc aaacgaataa
    39121 aaataaaaat gataattaat gctgtactca ttaatgttga tagtacatgg ctgtacacta
    39181 gcaaactcat actcaatgct agctttacag acggatactt ttcttctttt ccagagatga
    39241 tttgataagc ataaaataat acagggataa caagtgttat tgcgatagct tcggcaattg
    39301 cggaacgata gtagatgtct actgtccgat aagcagagaa aatatagaga caactaaata
    39361 aaaatgccgc ttttttttgt tttaaaaacc gctcgccata atgataagct acgagtgttg
    39421 tacacaagtt caataaccaa acgtaaataa tatagcttac aatcaaattt tttgtcatcc
    39481 aatataacat tacagctgga aaaaaagtca gaaagggata aaaataattt acaccatatc
    39541 cagtataatt gaatgtctca taattaatcg gactggtaaa aatagtcgat aaccccttga
    39601 ttcgagataa gtgaaaagaa agatctccag tggtataaat actctgtgta tttttgaaaa
    39661 agatgaaaga atatatacta ctaactataa ttaatccact caatattact acttttttat
    39721 ttattttcat tcttcttgtt tatctccttt ttagtcacat atcgagaatc tttcaactta
    39781 ttaggtgcaa atcgtttaaa acttgaatac accactaaac aataagtcag aatactgatc
    39841 cataaagcca tgagagcagt tggagtatat tttgttgtaa tttctatctt attttctcca
    39901 gcatttacat ccacattcac taagccatgt tttttataag agtcatttac gactttaccg
    39961 tttactttta cctgtgtacc taaataagca tatactggta ctgtcacttt ttgctttttg
    40021 ttgcttgcca ctgtgtaagt aatgttatta tctgcagctt tatacttccc tttttcccac
    40081 gattctccta cttttacttc atgtttttct aagtgaggcc tttcttttat cgcttctgtt
    40141 ggggcgtaat cgtataatcc tcccatatct gatgttgtat aacgtgggag tgtttcttca
    40201 ttgataacaa tatgaccgtg ttttgattgg ataacttttg cgtaattttc ttttgctgct
    40261 atagacgtga cgagtagaaa caccacagta gcgccaatga ttaaccatga atatttttta
    40321 ttcatagtct ttttcataaa aacaagcgtt atgatcattg aagaaaaaaa gatttggata
    40381 cctaagatac gccaaggaaa ctggagtaag cttatcggtg ttttttgaaa caaaaaccat
    40441 ggaaataaat tagttacgca tacccatgta gaaactacgc caacatagat gattttttct
    40501 tttttctcca tttctttcag tatgaataaa ggaaaaatca acgcaaccaa tcctaataac
    40561 cccatagtgt atgttgtaat atcgttattt aacgcttgaa tgatactatc tgaaatagaa
    40621 agtgcttcta gctgcaaatc tgttttgaag ggactgtgta tttcttgata attcatctgc
    40681 tgcaacatag gataccaaaa atagctagtt aatgcacaag tcaaaaaaac agcctttact
    40741 aaattcacga ccacaaattt tatatcgttt tttatttgct tgcttaaaaa caaacgaact
    40801 ataatcatac aagcaatcaa tgcactacac aatagtgtag ttaagacatg agtatacaca
    40861 agtagactta tactgacaga taaagcgatg actttttttt ctctattgaa tatcaatcca
    40921 taagcataat ataaaacagc tgggataatc gtaagagcga ttgcttctgc aattgcggat
    40981 cgataataga tatcaactgt tcgataagtt gcaaaagtat ataaacaact aaataaaaaa
    41041 gcagcatcta tctttttaaa aaacttttct ccataataaa aactaatcag aatcgtacaa
    41101 atatttaata accaaatata tagaacataa cttaatatta agttatttga aattccataa
    41161 aaaacgactg caggaattat tgtaagaaaa ggataaaaat agttcagtcc atctccataa
    41221 ttgttaaatg ttgtatagtt gattggccct tcaaaaatag aagataaccc tttgattcgt
    41281 gaaagatgaa aagataaatc acctgttgta taaatttctt gagcatttct cataaaattt
    41341 actgaatata aagtactaag taagataaga actactaaaa gaaatgcttt tttacttatt
    41401 ttcatagatt tgttgttctc cttttttaat tctattttca gtatactaga attgtctttt
    41461 tttaataagt tttgcgttaa atttttcata gcactagtat gatatactag aaaagaatca
    41521 atttttatta cttttaaata ggagaaaaaa atgaaaaaaa acaaaaacca aataatagat
    41581 atcattttta tgttatttct aagttttgct tacgtcatcc ctctattcat gtctaaggga
    41641 atctatcata gtgtcaatca ggatacttac tttcatttat ctcgaatcat aggactagat
    41701 aatgtatgga gttctccagt aaacttcaat aacttcgatc atcatggaac aatgatgaat
    41761 attttttatc catggcttac tctttatcca gcttttttat tttataaaat gatgggaaat
    41821 cttgttttaa gttataatat ctactatttt tttatcactt ttttaacaat ggtcgtttct
    41881 tatttttcta tgaaacaaat aaaaaacaat cgttatattt cgctgttatt ttcgattatt
    41941 tatacatttt ccgcctatcg tgccattgac atattccatc gtgcttcatt gggagaagct
    42001 gtcgctttaa catttttgcc tttgatacta atggggtgtt acgaaattta tattagagat
    42061 taccaaaaat ggtactggtt gtctattggc atgacgctag tagtgtatac tcatttactt
    42121 tctgtcgcta tggtttctgt atttattgga ggaacgttgt ttctttcttt ttatttttgg
    42181 gaccaaaaaa tcgctagact cttaagtctt ttaaaagcta ccgtcctcac ctttttttta
    42241 agtgcgggat tcttaattcc ttttattcaa caatctagag cacaagaatt gaaagtccca
    42301 ctgggaaaag aattaagtgg tatggctcct agtgatatgc tgacacatat tttaaataat
    42361 aactataaca actatactat tggattattc ttatttctcg gattgattgg tgcttttatt
    42421 tttataaaaa aattaactgc tgatgattta tttattttct ttcttggtgt atttgttctt
    42481 ttttgttcaa ccaatttatt tccttggcaa ctttttaacc atacaccagt taagagtcta
    42541 caatttgtct ggcggttaaa tggtttttct tctttattta tagcctatac gatgagtata
    42601 gtgatctatt atattttttc tactaaaaat aattcatgga aaataatggt ctttacgttt
    42661 cttgcactaa tattgcatct ctcaggagta agcaattcta tccatgctaa caaagattca
    42721 ttaacactta tagcacctga agacgctgtt gctatagctg aaaattacaa tcatactgat
    42781 tatgcaaaca aagagtcaat ctatcatcct gatatgatta ataatgatca atatttacta
    42841 ggtaaccagg aaataaatcc aacaactcat tttatgagta acaaacttac aattgaatta
    42901 gataattcga ataataaaaa tactgtcttg acgacaccta tttatcgtta taaagggcaa
    42961 gtggcttcta ttaatggcaa actagtacaa acaaaattat ctaagtttgg cacaactgaa
    43021 ttaactattc ctccaggtat aaataaagtc gttattactt atcagtacac aaaactagca
    43081 attgcttcaa gatatttatc tatcgttact ttgattttat ttttacttta tcgatttact
    43141 ttttctaaac aaaaacaacc gagaagagaa gtacaacatt ctcactagat ttttatttaa
    43201 gaaagacttt ttagctgtac acataaacag gctaaaaagt ctttttttat atttctttaa
    43261 tttgcttcat acattattta acatcgatat ttatactgtg aaacatgcgt ttcatccatt
    43321 atcaaagtat ttttatcgat aataaacttc atccaaaaac agaccttgtg cagggacggt
    43381 ttctcctgca tgttgccgca ctttgctttc aaatatttca tcgattgttt ctatcggcat
    43441 ggcacctgtg ccgatttcta gtaatgtccc catgataatc cgcaccattt tatataagaa
    43501 tccgtctccg acaaaagtaa aatgaagcat ttctcccttt cgttcgatag ataattcatc
    43561 aatcgtacgc actgtggatt tttttgattt tttcaatgca gaaaaaccaa tgaaatcatg
    43621 tgtacccact aatttttcgc aagctgcatt cagcttgtcc atatccaact cttgagggaa
    43681 ataaaagctg tggtttcgct caaatgctga aggaatcacg ttgttccaaa cataatagct
    43741 gtattttttg cccaccgcat tatatcttga atggaagcgc tcaggcattt cttcgattct
    43801 tttgatgaca atatcccgcg gaaggtaacg attcataaag tcgatcattt ctgccagtcc
    43861 aatttctgtg tttgttttaa aatttgctac ttgtcctcgc gcatgggtgc cagcatctgt
    43921 tcttcctgat ccaataattt ctatctcttc atttgtcatc tgatgcaata ctttttcgat
    43981 ttttccttga atggttttat cgtcatctcc aagtctttgc catcctgaat atctttttcc
    44041 gtcatattcg attgtcaact tgatgtttct catattttag tggctcctct gtcttccatt
    44101 tggtcttctc tctacctttt taagattgta gcacaaaata tagctccttg cttctctaag
    44161 acagaagcta tacaagaaaa ctgtggaaat atatatttca gaaaaacaaa aaacagccac
    44221 cggatgaagt atccgctgac tgttcaattt gacggctcaa gttttactgt ttgagatgca
    44281 agatactcaa ccaggcaatg ggcacataat taaagaaaaa actgattctt tggcaaaaac
    44341 ctattttatt cagtaatggc caagaattta tagaaggaat tcttgccagt ccataaatcg
    44401 ccgcaaaaag caaactgatc acagacagtc caaggtataa gtggcttacg tccatttgcc
    44461 cattttttcg atagatcaag aaaagaagaa ctggaaacaa taaaaaacca ctgtaaccta
    44521 aacctgatcc gatattatgg acccatgtcg agacattcca cgaagattca tgggtattga
    44581 tactgaacaa acctgtaaag atacaatcac ctataccata gaacgcgatg gctgctgtaa
    44641 ctagggtagc taacacacga gatgtactaa caaatgcagc atacaatgca ggcaatgaca
    44701 ggatgaaaaa gatccctgaa accacagacc aaataagaaa cgcttttctt acaggactgg
    44761 aaacctctcc aaatacactg atcacgctct tcatttgatc taattcagga taatacaatc
    44821 ctaatacgta cggagtcaaa aaatcactca gcacgcctaa taataaaaag aaaaaaccaa
    44881 atttacgtaa aaaatccatg atacgcctcc aataacaatt acctatgctt ttaattgtta
    44941 ttataaacga ctttatcttg atttaacaga aacctctatt tacacgaaca tctatataac
    45001 tcattaaaaa ctcgaatcat tttaaaaata ctaaatatct aacgttcaac gttcacttaa
    45061 tccatctaaa caatctttca atttgatttt ttccccactt cttttacgcg cgcctagctc
    45121 tcctattgca gtaaacaaca gatcacttga cgaatttaag gcagtttcca ttgaatcctg
    45181 gataacaccg ataataaatc caataccgac gatttgcatc gcgacatcat tagagatacc
    45241 aaacaaacta catgctaatg gaatcaataa cagtgaaccg cccgcaacac ctgaagctcc
    45301 acaagcagct aaagcagaca aaatacataa aaggactttc aaaacaaaag gtgcttcaat
    45361 ccctaaagaa tgtacagcag tcaacgtcat caaggaaatg gtaatcgcgg caccgcccat
    45421 attgatcgta gcacctaacg ggatcgatat ggaataagac tcttttgtca atttcaatct
    45481 ttcagccaac atcatgttta tcgggatatt tgcggcagaa cttcgggtaa agaaagcggg
    45541 aagtgcgctt tctttcaaac aaaagaaaat caatggatag ggattttctt taataaacaa
    45601 aaacgtgagg aatgggtaca caactaatgc gacaaacagc atcgtaccga tcaaaacaag
    45661 taaaagctgc agatactctg ccaatccagc gattccagtc gtagcaattg attgataaac
    45721 caatcctaaa atccctatcg gagcaaatgc aataatcact tgtacgactt gtgacaacgc
    45781 tatagatatc tgatccacca actcttttgt cgattctgaa cgtgctcgaa aagctagtcc
    45841 caacaataca gcccagaata agacgccaag gtaattcgca tcaataagag attgaacagg
    45901 attttgtgtg acattcgtca acatagtaga taaaacactt tccaaacttt gcggtgcttt
    45961 ttcagatact gtttcttgta aagtaatagg aacagtaaaa attgaactta caataactgc
    46021 tacaagtgca gaaagcaatg ttcccactaa atataagatc aaaataggct tcacgaatgt
    46081 cttattccca attttatgct tggcaattga cgccatcgtc aagaaaaaaa ccagaatagg
    46141 tgcgattgcc ttcaagcaac tgacaaacaa cgttcccaat attgaaataa atgtccatgt
    46201 ggggaaaaag ataccaaaca atattccgac taaaatacca acaacaatac gttgaactaa
    46261 cgacatatcc aaaaacttct ctaacaaatg accacccttt cacaatttta acaatcattg
    46321 tatcatttta tgcaaagaaa ctaaaggtat aattttctaa aaattctaac aatacaaaca
    46381 accatttctt gctaattttg tactttttct gtctacacgt tgttttttga gatattctaa
    46441 gttaggatgt tattaatggg caacttatca ggaaacgttt tcttatgttt ttgtccaatt
    46501 tttttgtgag gtgtttattc ttgaaaaaaa taaagaagga gagttatggc ttcctgacaa
    46561 tctttgtcgc ttgtataatg atggttttac agcgtatatt gatttcagca gtcactattc
    46621 ctacatatgc aacaaaccct ggtcgattct acatctatac atttttacaa acttccgttg
    46681 ttattggtgc aaatttgatc ccactttaca tgggttacca atatcaaaaa atcgcccgtt
    46741 taaaagtttt acattattta agtcgttttg cctttatatt cctaatagcc acactagttt
    46801 gcaatatctt tttttacgta caagctggca gcttgaatat tcgtgattat tggcttatcc
    46861 taacacctat cagtcagaat tactttactt atgctgtttc ttgtactttg cttttttgta
    46921 gtattcctta tacagttgga tttttaaata aattatcgaa aacaacaatt aaatatctac
    46981 tattattttt aacaattgga ttagttggct gctctactct atttaataaa gacccgtttg
    47041 cattacagaa tggacagagt attttatgga ttttttattt atttttaatg ggttatggtt
    47101 tgaaagaatg gaactggaaa gaaaaggtcc gctataagct tcctcaagta tttatcagct
    47161 tgattgtttt attcggtttg attattttga tgacacaaat ttcactcatc atcagaggaa
    47221 atacagatac agcgctgagg ttttctaaac catattctct cttcgcaatg tattatactt
    47281 tctcttcgtt tttattttta gaaatgctat ctgataaatt aggtataaaa ggaagaggaa
    47341 attttcttgc tgtatttttg attgtcactc aagttatatg taatttccct ttagtttctt
    47401 atcgcgtatc tacatttatg aaacgtgaat ttccaaactc agggaaggca tggctgataa
    47461 atatcgggca gttttttatt tgatatttat tagcagtgtc cctcctagtt atctttttat
    47521 tttatataca aaaaatccgt ttcattcatc gtttcatcga atacttcgct tttgattcga
    47581 ttgaacaatt aactcagcgt tggaaaaaaa gaattcattg gctttttgtt cataaaagtt
    47641 attttttagt tgcagcattt ttttactgct ttaccttcgt gcagattttc gttttagaac
    47701 caaaagaagg ttggaaagaa actatccagg ttgccttaaa aatatttact cagcgacaag
    47761 cacccatgat cctgacaatc atcattatta tgggattttt cttcttacta ttgttgattt
    47821 ccaatcgttt ttggtacgcc ttgactgcta ccttgatcat taacttactg ctcactattt
    47881 cgacagtaat caaaatggaa atgcgggaag agcctgtctt tccttcagat ttaaaaatgc
    47941 tgaccggatt gtcagaacta ttatcgatgg ttagcccagt cttattaatc gtgggcggat
    48001 tgatccttct cctattattg attactagta ttattgtaca acgtagacta caaaaacagt
    48061 attccttgaa gattcattgg aaacgtcgat ttatcagtat cgctgtatta ttaggatgtt
    48121 tttcgggtgt ctttttcatt aatcacaaaa attcgccttc tttcttgctg tttaatttat
    48181 ttaaagtaaa caagactttc tttaaccagc aaggcgccgt aaaagataac ggaccagtca
    48241 ttcaattcct aaacaatatc gacattaaaa tcatggaaga acctgctggc tattcgaaag
    48301 aaaaaattaa tggaataatg aaaaagtaca acacaaaggc agatgaaatc aaccaaacaa
    48361 gaagtgactg gttaaacaat cagacgatcg ttctcaattt aagtgaaagc ttcagtgatc
    48421 ctgcacgtgt ccctaatctg acagtaccta cagaccctat tccttacatc aaaagcatta
    48481 taacagaagg aacaggagga ttgatgttat ccgtcggtta tggtggcgga acagctaaca
    48541 tggaatggga aggactgaca ggcttgagta tcagtaacct gtctgcttcg ttagttacac
    48601 cttataccca gctagtggag cgtcagaaaa taagtccaaa tattaccgat ctattcgatg
    48661 aaaaaatagc catccatcct tttacagctg ctctttatcg cagaaaacaa gtgtttgata
    48721 aatttggttt tgacaggttc tattatttag acagtccgga taaattaact tatacggata
    48781 aaatagaaca aagcccacgc atatcggatg attcagcata caaagaaacc ttgaaagctt
    48841 tacaaagcaa tacggaaacg tcacaattca tccaattatc cactatgcaa aaccatatgc
    48901 cttatgatga ttactatagt gaattgaact acactgctga aggaactgct gtcattccta
    48961 atagaagaaa agaattacaa acttatatgc aaggccttca ctataccgat acagcagtaa
    49021 aaaaattcat ccaagaaatc gacaaaatcg ataaaccgat tacctttgtt ttttatggtg
    49081 accatttacc cgcaatctat agtgggaatg attcgaaaaa atatggatta gaacagcacc
    49141 agacagatta tttcatttat aacaacaagt atagtcgtga acaagcagct acgttaaata
    49201 aagaagttgt tgctcctaat aactttggtg ctatggctct tgagcatgcg aatatcaaag
    49261 taactcctta ctatgcgttg ttgacagaag tatctaatca tctacctgca ttaacaattg
    49321 atcctacaga aagcttgtct aatcgtttta atggaaaaca ggtctttgtt acagaggata
    49381 gtcaaattat ccaagaaaaa aatttaactg agaaacaaaa agaaattcta gaagattatc
    49441 gtctgataca atatgatctt gttgcaggta accagtacag tgcaacatgg gcgacacaaa
    49501 aaataaaaga ctaacaaata aactgagcaa ggggttgtga taaaagacat gtcacaaccc
    49561 cttgtttatc tcattaattt gcttgtccat aaacgatttg attaaagcca tttttcaatt
    49621 cattattcgc tgtctcgttg aagtaaagat aattatcggg attcccctga ttttgttgtg
    49681 tcaccaatac ttttggctga ttttgctgaa acccgaatag atagacgtgc tttttcagat
    49741 atggttctgt ctctgcatcg gaatagacgg ctgtgatttg atagtctgct tgacctgtcc
    49801 cactttctga ccattctgca gaaacaggca ctccaccaat agccatcttc cactccccgt
    49861 tcaaaatagc ttgagggact ttaagaccat ataagtccac actcatttga ttcgtataac
    49921 ttttgtattg ttgtcccatt gtttggcccc atttggtcat aaatgcctct aattgtgcgg
    49981 atttgtctgc attccacagt gtttgttcaa cttgttcgct gctttctgaa gaggaagatg
    50041 aagcctctac agaagaactt gaagtagatg tttgagttgt ttcagtcgtt ttggaagact
    50101 ctgacgaagt agaggtatct gctgtttctg tacttgctgc agttgacttg ctctctgtgc
    50161 tagttgttgt agtagttgca actgttgctt tcgctgtttc ttttgttgat tcttttttcg
    50221 attcattccc gttggtacaa ccagctaaca aaaaagctag accaattgtt actaaaatcc
    50281 tttttttcaa ttaaaaaact cctttcgatt actcccactt ctttattcta tcaaataagc
    50341 aatgtgattt tattgatttt tcgtattttc tcatcaatct ttcaaatctt ctaaaaactg
    50401 agaagcaccc gctgatgttg tctgtaatac atcagcgggt gcttctttta ttttaatctt
    50461 cgtgattttc caatttacct cacgctttat atttgtattt gaagaaacat agacttttag
    50521 tcatcatcgt cttcctcatc caaatcttgt cggacagttt ttccttggag tctttgtact
    50581 tggtagatga tttctttatt gaaacttaaa agttcaacaa gcaattgttg caagccatat
    50641 ttttcttctt tttcagctaa tttgattgcc cgtgtgataa agacattttg gaaatcaaaa
    50701 tcttttgcaa agttttccaa cattgttgag gctggtaaat atttgttttg accatgttcg
    50761 taaatttttc cataacgcat gacttcttct aaagtagacg gaacgatttc attttcaatc
    50821 actaactcat gagagatttt attgaaccat ctcgcttctt gatcagcata ttctgaaaaa
    50881 agggtactta attcttgcga agatgtaccc aaaacataca attgtgcttg gatcaatttc
    50941 atttcttcta atttaaaatt tgctaataca tgccccacca tggcgccagc agttggttta
    51001 tgatggtcga tatctgcttg ttttgtttct tgaacaaatt tttcttccac tatattcatt
    51061 gatttacgcc tcttttactt ttgctgattg gacttcataa cctaattttt ccacaactgc
    51121 agctaattgt tcagggtgga cttcatctgg atcaaagttt gctttgattt tgctcgcatt
    51181 aaacaaaact ttcgtattgc ttaccccagg ctgttgagaa accgcatgtt cgattttttg
    51241 catacagctt ggacaagcta gtgtatctaa ttgcataata atttttttca tcgtagttct
    51301 tccttccttt ttcttgatag tcttattcta gattacagct tccataaaaa aattgattct
    51361 tatcaagttt tacgattttt cttctttgct ttcgtgtcca aaatacaata aacgcatcgc
    51421 gttaaagata acgatcaaga tactagcttc gtgaacgaac atcccactag ccatgtaaat
    51481 aaacccggca aataagccgt tgagtaaaaa taagacgaca ccaatggcaa tcactacatt
    51541 ttcacgggta tttaaaacag ttttcttagc caagcggtag gcatgaacca acgattcaaa
    51601 attagattgc atcaagacaa cgtcactcgt ttcgatagca acatccgttc ctgatcccat
    51661 agcaatcccg atatcagccg cagccaaaga gggagaatca ttgattccat ctccaataaa
    51721 agcaacgcgc aatccttgtt cttggtattt tttcacaaat tgaacctttt cgtctggtaa
    51781 taattcagca tggacttcat caatgcctaa catatcagct acataatcag cagtcatctg
    51841 attatcacct gtcagcatca ctaactgttt tgctcctgct tgtttcaact tagctaattg
    51901 ttcagcgact tctggtcgaa tcacatctga cacacctatg atttgagtga tttttttgtc
    51961 gattgctaca ataatgaccg agctgcctgt ttgttgtaat tgatgtaaat cttgtacttg
    52021 ctttggtgtg agagaaagtt tgtgagcggc aatcaatttg gtgttgcccg cacaaactgt
    52081 atgaccatca atctcagctg tgattccttg tcccttgatt gtctgattat ctttgactgc
    52141 taattgttga aaatcaatgt ctttctcctg agcataatgg atcacggcgc gccccagagg
    52201 atgatcggat aacgtttcta atcgagccac taaagctaag ctgtcccctt catcctctgt
    52261 atagttcttg atagtggata cagcagtagt tcctttggtc aatgtaccag ttttatcaaa
    52321 gacaaaagta tcgattttgg aaaaagtatc cattgcttca ccgcctttga ctaagatgcc
    52381 ccgtttcgct ccattaccga ttcctgctac attcgaaaca ggcgcaccaa tgactaaagc
    52441 gccaggacaa ccaagaacca aaacagtgat tgctaaacga aaatcacgac taatcagacc
    52501 aacaaccaac gcaataagta aaacggttgg agtataatac tgagaaaatc gatcaatgaa
    52561 tttttccgca tgggatttgg tatcttgtgc ttcttctact aattcgataa ttttggcaaa
    52621 ggtcgtatca tctccgacct tagttgcttc aatcgtcacg tagccatctg ctaaaatcgt
    52681 tccagagaag acttcatctc cactgatttt gacgacttgt cgtgattcac cagtcactgc
    52741 ggcttcatcc gcataccctt tcccgtcaat gactcgtccg tccacaggaa tagctccacc
    52801 agtttttact aagacgatat cgccttcttc cacgtcatcg atttccactt cttcagtcgt
    52861 tccatcttct tggacaacac tagcagtaga tggggccatc tcggtcaaag ccttgattga
    52921 ctcccgcgtt ttggtcaatg ttttttgttc cagatagcta ccaaacaaaa acaagaatgt
    52981 aacgatagct gactccttgt attctccgat cataaaggca ccaagcacag caatagtaac
    53041 gagtaaatca attgagataa ctttgacttt cactgcctga tacgcatgga tcataatagg
    53101 tatgaccgca ataatagaag ctatggctag agcaatgtta tagaacaaga caaaaccagt
    53161 aaattttccg ataaaaccaa aaataatcaa cacagctgat aaggcggtga tatgatttcg
    53221 atgctcttgg atccactttt gtaatttcat ctttctccct cttttccttt cattcttacg
    53281 agactaagta tagatactta tccatcataa aaaattgacc actatcaagt ttagtcaaaa
    53341 aggcggtttt cttttggtag aatacactac aaaaaatagt tagcaagaag actcactaaa
    53401 agtgatcttg ccaactattg tcgtttctat cgaaattttc attgaatgat tttcctgtac
    53461 agcatacatc ggagatctat ttctttatct aagattttta tcttgctaat tttttccttt
    53521 agtctttcaa atccacgtcg ttcatagaat tgatacgtac agccactatc tgtaaaaagg
    53581 aatatttctt ttcctttctc tcttttttca aattctgtta gcaacttggt accgatgcct
    53641 tttgttttca aatcaggatt tgcagctaaa aaaatgatct ctccatctgg cgaatgcttc
    53701 tttaaatatg ctgcaagcat ttgttcattt gctgtctcgt aagctccttt actttcttta
    53761 gcaaatatat tttgtaaaaa atcgaatatc ttaacatata tttgctgtcc aaaagaacga
    53821 tgtttctttt tttctccttt tatctccgcc agcaaaacac ctgccaactc gtcctctgca
    53881 tacaaagcaa gaatttgagt tgctcgattc aactccatat acaaaaaata tcttccgtaa
    53941 agattcagca gaagttcatt ttccatatat ctctcaaagt tcattccttc aacagcaaaa
    54001 tagatagctt ttttgtaatc tttcttttct aagggtttaa aagttagttt catcatttcg
    54061 cctcctcaac ttcaatgatt gtgttatact tacattataa tagacacagt gtctactatc
    54121 tataatcaat catctataag tttgtcgatt aagcgacagc tttgctttga tatgtcggat
    54181 aaggagatag gtaaatgaaa aagacagata gacgcgtcaa aaaaacagaa aaagctttgg
    54241 ctgaaacact atccacatta ttagtaaata aaaagattca agcaatcact atacgcgaac
    54301 taacagaaac ggcagatgta catcgttcga ctttttatac acattataag gatatctatg
    54361 atctatatga t
//
LOCUS       DADLIO010000011        53719 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.011, whole genome shotgun sequence.
ACCESSION   DADLIO010000011 DADLIO010000000
VERSION     DADLIO010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 53719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53719
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.011"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            160..840
                     /locus_tag="JOX41_000788"
     CDS             160..840
                     /locus_tag="JOX41_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAY6448553.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            930..1964
                     /locus_tag="JOX41_000789"
     CDS             930..1964
                     /locus_tag="JOX41_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAY6448554.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            1978..2313
                     /locus_tag="JOX41_000790"
     CDS             1978..2313
                     /locus_tag="JOX41_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448555.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            2297..4777
                     /locus_tag="JOX41_000791"
     CDS             2297..4777
                     /locus_tag="JOX41_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448556.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            4833..6392
                     /locus_tag="JOX41_000792"
     CDS             4833..6392
                     /locus_tag="JOX41_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAY6448557.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQISYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            6389..7753
                     /locus_tag="JOX41_000793"
     CDS             6389..7753
                     /locus_tag="JOX41_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAY6448558.1"
                     /translation="MKIVIIGASHEGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            7924..8994
                     /locus_tag="JOX41_000794"
     CDS             7924..8994
                     /locus_tag="JOX41_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAY6448559.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            9009..9677
                     /locus_tag="JOX41_000795"
     CDS             9009..9677
                     /locus_tag="JOX41_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6448560.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            9697..10275
                     /locus_tag="JOX41_000796"
     CDS             9697..10275
                     /locus_tag="JOX41_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAY6448561.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            10676..11587
                     /locus_tag="JOX41_000797"
     CDS             10676..11587
                     /locus_tag="JOX41_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAY6448562.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(11965..12882)
                     /locus_tag="JOX41_000798"
     CDS             complement(11965..12882)
                     /locus_tag="JOX41_000798"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HAY6448563.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELDKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            13084..13521
                     /gene="zapA"
                     /locus_tag="JOX41_000799"
     CDS             13084..13521
                     /gene="zapA"
                     /locus_tag="JOX41_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HAY6448564.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            13579..14127
                     /locus_tag="JOX41_000800"
     CDS             13579..14127
                     /locus_tag="JOX41_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HAY6448565.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            14242..16602
                     /locus_tag="JOX41_000801"
     CDS             14242..16602
                     /locus_tag="JOX41_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HAY6448566.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKIENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNTYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            16689..17003
                     /gene="trxA"
                     /locus_tag="JOX41_000802"
     CDS             16689..17003
                     /gene="trxA"
                     /locus_tag="JOX41_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HAY6448567.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            17185..18963
                     /gene="uvrC"
                     /locus_tag="JOX41_000803"
     CDS             17185..18963
                     /gene="uvrC"
                     /locus_tag="JOX41_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HAY6448568.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTCQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMVKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            19108..20007
                     /locus_tag="JOX41_000804"
     CDS             19108..20007
                     /locus_tag="JOX41_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6448569.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            20000..21262
                     /locus_tag="JOX41_000805"
     CDS             20000..21262
                     /locus_tag="JOX41_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAY6448570.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPIRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            21423..23321
                     /locus_tag="JOX41_000806"
     CDS             21423..23321
                     /locus_tag="JOX41_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HAY6448571.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(23651..24370)
                     /locus_tag="JOX41_000807"
     CDS             complement(23651..24370)
                     /locus_tag="JOX41_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HAY6448572.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLVEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     gene            24707..25039
                     /locus_tag="JOX41_000808"
     CDS             24707..25039
                     /locus_tag="JOX41_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448573.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            25026..27029
                     /locus_tag="JOX41_000809"
     CDS             25026..27029
                     /locus_tag="JOX41_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HAY6448574.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            27048..27518
                     /locus_tag="JOX41_000810"
     CDS             27048..27518
                     /locus_tag="JOX41_000810"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HAY6448575.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            27539..28123
                     /locus_tag="JOX41_000811"
     CDS             27539..28123
                     /locus_tag="JOX41_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HAY6448576.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            28138..29124
                     /locus_tag="JOX41_000812"
     CDS             28138..29124
                     /locus_tag="JOX41_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HAY6448577.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            29114..29425
                     /locus_tag="JOX41_000813"
     CDS             29114..29425
                     /locus_tag="JOX41_000813"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HAY6448578.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            29447..31228
                     /locus_tag="JOX41_000814"
     CDS             29447..31228
                     /locus_tag="JOX41_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HAY6448579.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            31221..32597
                     /locus_tag="JOX41_000815"
     CDS             31221..32597
                     /locus_tag="JOX41_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HAY6448580.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            32604..33239
                     /locus_tag="JOX41_000816"
     CDS             32604..33239
                     /locus_tag="JOX41_000816"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HAY6448581.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            33269..34624
                     /locus_tag="JOX41_000817"
     CDS             33269..34624
                     /locus_tag="JOX41_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HAY6448582.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(34816..36210)
                     /locus_tag="JOX41_000818"
     CDS             complement(34816..36210)
                     /locus_tag="JOX41_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAY6448583.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            36302..37273
                     /locus_tag="JOX41_000819"
     CDS             36302..37273
                     /locus_tag="JOX41_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HAY6448584.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            37270..38052
                     /locus_tag="JOX41_000820"
     CDS             37270..38052
                     /locus_tag="JOX41_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HAY6448585.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(38221..38592)
                     /locus_tag="JOX41_000821"
     CDS             complement(38221..38592)
                     /locus_tag="JOX41_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAY6448586.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            38726..39169
                     /locus_tag="JOX41_000822"
     CDS             38726..39169
                     /locus_tag="JOX41_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HAY6448587.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(39212..40021)
                     /gene="yidA"
                     /locus_tag="JOX41_000823"
     CDS             complement(39212..40021)
                     /gene="yidA"
                     /locus_tag="JOX41_000823"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HAY6448588.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(40040..41407)
                     /locus_tag="JOX41_000824"
     CDS             complement(40040..41407)
                     /locus_tag="JOX41_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAY6448589.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(41391..42221)
                     /locus_tag="JOX41_000825"
     CDS             complement(41391..42221)
                     /locus_tag="JOX41_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HAY6448590.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLEDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            42384..42821
                     /locus_tag="JOX41_000826"
     CDS             42384..42821
                     /locus_tag="JOX41_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HAY6448591.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            42897..43517
                     /locus_tag="JOX41_000827"
     CDS             42897..43517
                     /locus_tag="JOX41_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HAY6448592.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            43706..44212
                     /locus_tag="JOX41_000828"
     CDS             43706..44212
                     /locus_tag="JOX41_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HAY6448593.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            44229..45128
                     /locus_tag="JOX41_000829"
     CDS             44229..45128
                     /locus_tag="JOX41_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HAY6448594.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            45215..46099
                     /locus_tag="JOX41_000830"
     CDS             45215..46099
                     /locus_tag="JOX41_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAY6448595.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(46291..46362)
                     /locus_tag="JOX41_000831"
     tRNA            complement(46291..46362)
                     /locus_tag="JOX41_000831"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(46327..46329),aa:Arg,seq:ccg)
     gene            46422..47756
                     /gene="rpoN"
                     /locus_tag="JOX41_000832"
     CDS             46422..47756
                     /gene="rpoN"
                     /locus_tag="JOX41_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HAY6448596.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            47959..48996
                     /locus_tag="JOX41_000833"
     CDS             47959..48996
                     /locus_tag="JOX41_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SorC family transcriptional regulator"
                     /protein_id="HAY6448597.1"
                     /translation="MLDEIKMIESVAPDIIEVLQERYKILRNIYWMQPIGRRSLSESM
                     GITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSLENFMDQLLGTHQTEQQLA
                     EYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEGENIIAVMGGTTMAVVAEQ
                     LSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKANGNHRALYVPEQLSLATYN
                     SLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEKELVMLKQANAVAESFGYF
                     FNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAIRAYMKNAPKQTWLITDEA
                     AANEILKGVTL"
     gene            49037..50038
                     /gene="gap"
                     /locus_tag="JOX41_000834"
     CDS             49037..50038
                     /gene="gap"
                     /locus_tag="JOX41_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAY6448598.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            50148..51338
                     /locus_tag="JOX41_000835"
     CDS             50148..51338
                     /locus_tag="JOX41_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HAY6448599.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            51442..52197
                     /locus_tag="JOX41_000836"
     CDS             51442..52197
                     /locus_tag="JOX41_000836"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HAY6448600.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            52313..53611
                     /gene="eno"
                     /locus_tag="JOX41_000837"
     CDS             52313..53611
                     /gene="eno"
                     /locus_tag="JOX41_000837"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HAY6448601.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
BASE COUNT        17827 a         9355 c        11351 g        15186 t
ORIGIN      
        1 ttaataaaaa aggaagaata ttcatgtaaa cgattttatt gtttttttct cttttataca
       61 aaaagggtca taatttcaag taagcggatg aattcatgag gattttttgc atactgtctc
      121 tactatactt aggtcactaa gaaaaaggag tgatttatta tgaaaaagaa catgattggg
      181 acattattac tttcaacact tcttctaggc ggcttggcaa caccagcttt tgctgagggt
      241 caagcgactt caaaaggaga tattaccttt actgaaccaa caaataccgt ggagcctctt
      301 aaccctactg atccttcaaa accagtagag ccagcagatc cggaaaatcc agcaactggc
      361 cagacaggtc ctttaacact ggatgtagtt cccgaattgc catttggtac acacgagatt
      421 gaaagcggaa caaaaacgta tcaagtagac gcttcaaaaa acgatacacc ttatctccaa
      481 gtatcagatc gtcgaggtgt aggtgcagat ggccaagcac aagggtggaa cgtgacagtt
      541 tcggtttcag attttgtaaa cggttcacaa gttttgcaag gcgctgaatt agattttgga
      601 acatccactg ttaaaagtac gtcagataac gaatccactg gaccaactag tcaaactgta
      661 actgggttga gtaaagcaag tgcagcgaca ccaatattta cagcagcaaa agatcaaggt
      721 ctgggaacat ggctttctgt ttatgatcca gcaaatatca cactgaaagt gccgaaagca
      781 gcagctggaa cattcacggc tgatttgact tggaacctcg tggctggccc agtagcatag
      841 agtatgaaat aaattcaaca aactgcggtg aaaatactat aggtgaagga ttttttaccg
      901 cagttgttgt tgaaaggatg tggtggacaa tgaatcaaag taaacgactg tttgtttcgt
      961 ttttttctat tttaagtcta tttttcattt ttccgtcaat cagccaagca aaggattcag
     1021 caggagactt tggaatcaaa ccggtatttc cagagaacca aatagataaa gcaatcggtt
     1081 attttgattt attagtggca ccggaacaaa atcagacact agaagtaatt atcagcaatt
     1141 cttcagatga agaacgaaca tttgaggtct ctgtcaatcc ggcggtaacg agtgatggtg
     1201 gaacgatcga ttatagtcaa aaaaacccaa cgttagatga gacattgccg tttgatgtcc
     1261 gtgacgtttt gctcattgcg aaaaaggaaa tcaatgtatc agcacatgca gaaacaactg
     1321 tacctataga agtgaaaatc ccagcaaaaa gctttaaggg acgtgtatta gcgggtattc
     1381 atgtttcacc taaagaagaa gctgaaacag aaaatgctac agaaggagca caaatcaaaa
     1441 atcgtattgc ttataatctc gcagtcgttt tacaagaaag tcaagagacg atagaaccgg
     1501 atctgaaact tttatcagga gatttggacg aggtcaacgc aaagccaact gttcagcttc
     1561 gtttccaaaa tcctcagcct aggattatca gcaatttgat atttacgagc aagatctttt
     1621 atgaaaatca gctttatatt gaaaatacgt ctaatgcatt tttagttgca ccaaattcga
     1681 attttcactt gaatcttgat ttagctggtg ataaagcaaa agccggcgat taccgcgcag
     1741 aaatcatagc aaaatcaggc gacagtaatg aatggcgatt tacacaaaac tttacgatca
     1801 aaaaagaaaa agcacaaaaa gtaaatgaaa attccgtttt tgcagtacaa gaacaatctt
     1861 tcccatggct ttatgcagga ttggttgctg cagttctagt gttatggttg attttgctgt
     1921 ttttgtgggt ccacaagaaa aagaaaaaag gagaaacaac atgatgaggt gatttcgttg
     1981 aaaacatcga tcttattggg agggattatt gcaagtttgc tgttcttcag ctggcaagag
     2041 ccagtccaag cagataccaa aagttcaggt acgattacat tttatgatct aagtccaatt
     2101 ccgcatccaa gtggttcagt caatggcgca tcaaaacagc agacacagct accgatttat
     2161 aaagaatcta atcaacatgg cgtattcccg gagacgaatg aacaaaagat ccgttttctt
     2221 tatttgatca ttggtataga attatggctt cttgcgtggt tgttgttatg gagaagaaag
     2281 gaaaaggagg atgaacatgt tgctacaaaa taaattttca ttttttcgct ccttcttttt
     2341 tacttcgctt tttgttttaa gtatatttat cttttcacct tcggcagaag ctgttggagc
     2401 aacgcctcct gccatttctt atgatccata cacgtatgaa aatatcgtac ctccaaatgg
     2461 tggacgtagt gcagtcaatg gcgggaagct tgtccaacta actggggcta accaattgcc
     2521 taaattgact gctacttatt tgaacgatgg ttcaaatgat ccttggaaag gtggcacggt
     2581 ccgttttcat tgggaaagcc atgtgaaact aacaaatgta cttgatttgg tgaatatcac
     2641 tgcacaagga tttgcatttg tggcgatcat caatttgccg gaacatgtat caagcagtga
     2701 tgtattaaaa gcaattgact ggaacaacgc ctacttgtat attgccggtg cccccatcaa
     2761 ggttactagc ggaagtttat tatcagcagg aagccatacc ttgcgttttg ggatggggtc
     2821 gtgggataca aatactctat tgacagatat tattgctatt attacgcgag gcgaattcaa
     2881 cgtggacgat atcccgcttc aatttgatgt tacagctaat gtcgcgaaga tgacagaaaa
     2941 cggagataaa tatgatacga gtccaaacaa aattttgacc aagggtaaat tacaaccttc
     3001 tatgtctaaa aaggccgttt tttctgttga tttttatgat tcgaataata ttatccaaga
     3061 tcgtatgttc aattcgattt tagctccagc tgcaggtaga ttttatccta aattaactgg
     3121 cggaaacttg aatccaggag catatgcatt ttctgcaagt gcagagataa atacgtggaa
     3181 tagttacatc tcaccaagtg attcaacagg aaaatataat acatttgctg ataccacaga
     3241 atacgtggat ggaaataacc agaaccttcc aggctctacc aatagtcgga cattgacgat
     3301 ggggctgact gaaggacgtt ttgatcagtt gccatttagt cgctttgatc gcgtagtcaa
     3361 ctattttaca ggaaaaaacg ttacacaagg agcaatactg actcatactc cagcaagcac
     3421 aagtggattg aatcagacag ccaatatcgt gtacagtggg aaagatgcgc aaggcggatt
     3481 gctttctcct gttgctttaa aggtattgga gcagtacaag ctagacggaa cggttttacc
     3541 aacaaactta acagccgata gtcagtgggg aaagctcctt tcttctgcat cgtaccaagt
     3601 cacggccaat tggtcagcaa ctgaactaaa aaagggttcg atccattaca ggctttattc
     3661 gaaaggaacc caaaaattag cgacaggatg gacagatcaa cttttccaaa cgatccaatc
     3721 aaataacggg ggtgtaaata cagctacttc tacactacct gcattggctt cagggcaata
     3781 ttattttgat tatcgcttgg tggacgatgt acttactaac atgtatccgt cttttgcgta
     3841 caaatggcag tctgaacaag ctggaatcac cactcttcct caaataacag tggctaattt
     3901 tccatctgtg agtgcagata gtcagctaaa aaaccttagc agacaacctg agacaggaga
     3961 tcccctgtct gctctatcag gagatacgat tcaagaaaat gtgacattca cgttaacaaa
     4021 atctggggat gcgataaccg acaaaaaaat cacgatctca cttcctgaaa atactactta
     4081 tatcaatggt tccttaaaat taaatggtac aactatcgca gataccggca ttcaacaagg
     4141 agtttctgtc ccagcagatc tattgagcaa aataggagat accattcatc ttacttacaa
     4201 ctatcaatta aatactgtag atacttcttt acaatccgtc agcatactga caaaggcagc
     4261 tgtactttcc agcaatatta cattagcaga tggtgctaag cttcctaacc cagttgtcca
     4321 aacatctgct aaaacaattc ttgtccccaa acaagaatta acattagtta atgtaccaga
     4381 tgattttaca tttggtaacg atctccccaa accgttgaag acaagttatt atgaatcaaa
     4441 aggcgatttt tcttttgatg tgcgggatac tcggcttcca agcacgtctc cttggcaact
     4501 gacaggtaca ttgacttctt tatttaagaa tgatcaaggt caagaattaa gcggaacaaa
     4561 attatacttc aatcattctg gatcaaagca attgattcag caaggtcaaa acacgttgat
     4621 ttatgagagt gatggaacag ctaaaggaga ggttctcgtt gactttcccg ataccgatgg
     4681 tttactctta gaggtaaata gcagtacgaa tgctcaacct ggcgcaacgt atcaaggcat
     4741 ggtcacatgg gaactgacag ctgggccaac cagctaagtg attagaattt gtatggatct
     4801 gtgataactg tcacagatcc tctttttcaa ggatgagaag gaaacttctg ctgttaaaat
     4861 cagaaatgct tgaaggagtg gacttggaac ttttcagttt gcttgaaaaa aatgaacaac
     4921 ggcaaatcaa acttttccaa cttttattag aggaaaaagg agaggtttcc gttaataacg
     4981 tacttacccg cttatcagtt gatcgggcta ccttgaaaga agatctgttt tatttacaag
     5041 ctaacttgga aaatatcaaa caattggaaa ttgttatcca agaagggaat attttattaa
     5101 tcagacatgg aaatatagca gcagtcgatg tttattatca ttgttacttg cgctattcta
     5161 caaaatatca gatacttctt tatctgttgg aaaatggctc atttgatcgg cagaaacttg
     5221 tcatggaact taatatcagt tcggctactt tgtctcgcag agtgaaggaa ttaaatgatt
     5281 ctttaaatga gtttcatctg aaaataaaaa gcgggcggct gaccggtcca gaaagtcaaa
     5341 ttagttattt ttatttccaa ttattttggt ttggacgtcc ctatcttgaa aacaaaaaag
     5401 aatacagtga tttatcagga aacacttttt tagatctgct gcaaaaagag tttagttttg
     5461 ctattacaga agaaggacga ttgaaatttg aaatatggct ttccattatg aagaagcgaa
     5521 tgcgctgtac gaaaaaatcc aaaccagatt atagcaatct tcctgttgga ttgtttcaaa
     5581 cgacacaatt tttattggac ctccatacat ttttgacccg ttacttcttt caatatgcct
     5641 ttccttggaa tcaaaatgaa acgttggttt tttatctttt catgatcagt aactttacat
     5701 tagatacaca taactcgcat gtccaggagt ttttgataag cgaaaaatac aaagacgacg
     5761 tagtagctca attgaatcga acgtttaaac aatcgataga agaatatttc tctttttatg
     5821 tttttccaga agagatttcg caaaagattg cgttgacagt gatgcaaaat cacgctcatt
     5881 ttgcctattt tagaggatgg atgaatattt ttggccaaga aggattaaaa cagcggttaa
     5941 ctgaagtaga agataaacaa ttcctggttt tatgtgaaag attggtcaga caaacatttg
     6001 ctattgttga ttttactgaa gtagacgagg aaaatgcccg ctttgaatta tttgctcgct
     6061 atgcatctat tttacggacg ctgatcaagc agttagaatt acgtctgcaa attgcttatg
     6121 atcttcctta tgaaaggcta atggcggata tcgtgaaaga aatcatccag gaacaattgc
     6181 tgaatacgat caaatatgat ttagtcgaat acgagaaaga aaagcagtat gatatcattt
     6241 tgactagcca attgaaagag tacccgtcac agaagtccgc taaagttttt gtattcacta
     6301 gcaacgaata taattatgat ttcccctatt tgaaccaatt tttaaaagaa tgttatttag
     6361 aaaaattgaa tttaaggatg aataaaacat gaaaatcgtg atcattggtg cttcccatga
     6421 aggcatcaca gctgccctaa atctaagaaa acttcaaccg aaagcagaag ttttactgat
     6481 cgatgaagat cataaagatg gactaggcta tgtttcaaat ggaatcaacc tttatttaaa
     6541 aggaaagata cgtagtttag ctgaagttgc ccataacatg cggactcttc aagaaagtgg
     6601 ggcaaaactg atcaccgaat ggagagtaac tgaacttgat ccagacaaac atcagctcat
     6661 cctcgcatcc aaagaaggaa aaaacgagac cataacctat gataaattaa tcgtagcgac
     6721 aggttcctct cctgtcacct tgtataaaca aattgaagct gaaaatgtct acacctataa
     6781 aaatctagtg caatctaagc aagtacttgc cgctttaaaa gaagcaaaag aagtagtgat
     6841 cttcggtgct ggttacattg gattggaatt agcagatgct ttgagaaata aaggatacat
     6901 tattcatcta gttgattata tgccgaatgt tttatcaaga tatttcgata aggatatgat
     6961 caacagtttt caaaatcagc tgcaaactaa gcaaataaat ttttatccaa atgaattctt
     7021 gatcgattgg aaaaaatcag aagagaaagt agtatccgta caacttctgt ctcaaacaat
     7081 aaaggcagat atggtcattt tttctgccca aactcgtcct aatacgacat tgttaaaaga
     7141 aaaagtggct ttgtatgagg atgagactgt gatagtcaat gaatatctgc agacaagtga
     7201 tccggacatc tatgcgattg gagatatcgt cccagtcagt tttgacaaaa ataaacggca
     7261 tctcttttta cctttagtta ctcgagctgt acatatggca agagcagtag cgctaacttt
     7321 gagtggtcag ccaaccgctt acgacctcag acaaaagata acagcagcag tcattataga
     7381 ctacttttta ggaactgtag ggctgacaga agatgaagcg ccattcttgg aacaaaatac
     7441 cggttcgtgt tcaggagaat ttgatctatt tccacaatac gacgaagaaa acaaaacagt
     7501 aaatgcaaag ctgatctacc atccggatac attagaaata attggcggac agctgataag
     7561 ccaagaattc ttattatcag atttgaacct gcttgcggat atcgtgaaac acaaaactac
     7621 gattccacag ctagcagttg aggattttgg atttctgtct gaatacacct ctcgttttca
     7681 ctacctcaat gagttagctt ttaaagtact agctaagaga gcaaatagca atagagtaga
     7741 taaaagactg tgagaaatat cacggtcttt tattgtgtgg ggatataata aatattaatc
     7801 aatcgagaat aaaaaattca tataatgaaa tagcggaaga attttttgag cataatattc
     7861 gccaaaaatt tatcaagtga taaaattgtt gtataaaatg attatttcag gaggaggagt
     7921 taaatgtttt tagcattaaa tgaaattatg cattcaaagt tacgttatgc gttagttgca
     7981 ggggtgatgt ttttgatcgc ctacctggta ttttttttga ctgggttagc ttatggctta
     8041 gctcaagata atcgaacagc agtcgacaag tgggaggcag attcgattgt gctttcgaaa
     8101 gatgcaaatt caaatctagg gatgtccatg attactaaga agatagcaga agaagtcgaa
     8161 ggtgggaaag tggcgtatct tgcccaaaca cctggagtcg tgactagtaa agacagtaca
     8221 gaagaaggaa aaatcaatgt tagcttcttc ggtatcgata aaaatcaatt catcatgccc
     8281 aatcttgttg aaggaaaagc ttttgataac gatgatgagg cagtaggcga tattagtttg
     8341 aaagaagaat atggtctagc cataggagat acagttaagt tatctggtag tgacaagacg
     8401 tttaaactaa ctggctttac ggatcatgcc aaattcaatg tctcaccagt tctctataca
     8461 accatcaatg cttaccaaga aatccgcttc gaaaaagaag atacaagtga aaatgcacgg
     8521 attaacgcaa tagttgtcag aggtaaaatc agtaatttac ctgaagattt agaacagatc
     8581 aaaatttcta aattcatcaa tgaattacct ggatataatg cgcaagtatt gacttttgga
     8641 tttatgatcg gatttttgat cgttattgcg gctattgtga tcgggatttt catttatgta
     8701 ctgacgatgc aaaagattaa tatctttggt gtaatgaaag cacaagggat cacaggagga
     8761 tttattgcgc gttctgtagt ggcacaaaca ttcattttat catttgttgg tattcttctt
     8821 ggtctattag gaacagtggg aacatccctt gttctacctg atgcggttcc attccaaagc
     8881 aattggctgt tttttggcgt cattagcttg ttgatgttag tagtagctgt gttaggcgca
     8941 ctattttctg ttcggacaat cgtaaaaatc gatccgttga aggcaattgg ataagaagga
     9001 ggaagaacat gaaagcaata gaatttaaag aagtagaaaa aagtttccaa gatggcgacc
     9061 aagtagttaa agcattgaaa gaaacaacca tgagtatcga taaaggggaa tttgttgcaa
     9121 tcatcggtcc ttctggttca ggtaaaagta cttttttgac tttggcaggc ggattgcaga
     9181 cgcctagcag tggctctgta tttatcaatg atcaagaatt cagtaatcaa aaagaaagcg
     9241 aacgcgttaa actacgtttt aaagaaattg gctttatttt gcaagcttcc aatctggttc
     9301 cttttctgac agtaaaaaag cagttattat tagtagataa gattaaacat gaacatcgtc
     9361 aaaaagaagc aaacgaatta tttgagcagc ttggcgtgga taagttgatc aacaagtatc
     9421 cagaagaact atctggtgga gaacggcaaa gggtcgcaat cgctcgtgca ttgtacaatg
     9481 atccgtccat tattctagca gatgaaccaa ctgctagttt ggattcagaa aaggcacgag
     9541 aagtagtcga tatcttggca aaagaatcaa aagacaaaaa taaagcaacg atcatggtta
     9601 ctcacgatac acggctgatt gacaaatgcg atagaatatt tatgatggaa gatggtgtat
     9661 tgaaagaaaa agaataacca aaaagcaggt ggaaaaatgg tccatcgata caacaaagat
     9721 acacagcaaa aaattttgaa agaagcgact gacttgttta tgtccaaggg atatctcggc
     9781 acttcaacaa gagaaatcgc acaaaaagtt gggatcaccc agcccaatct ctatcattat
     9841 ttcggtgata aagaaaaact atatacggca gttttagaaa accacttaaa agatgttgga
     9901 aaagctttga gagaaatcgt tcaaacaagc gaaacgggat ttcaagtaac cttgacaaaa
     9961 atggcgcagt ttttgattga gacacatctg gtcgatttgt ttctgatgct tcacgatctt
    10021 gaaagcaatc tttcaaagga aacaagagat catcttttct ttctatggaa gaaaaattat
    10081 cgtgaacctt ttgaagaaat cttttcagca aaccaatctg tgctaagaaa tgggatttca
    10141 aaagaaatcg cagcaaggca ttttttctta gtgttagcac cttacatcac tcggtcgaaa
    10201 agacctgtgg aagaaccgct aaatgtggcg caattgatcg atttatattt gaatggtgta
    10261 ttaggagaag cgtaaagctg ttatataggg agaaaatagt taggtgaaga agcaagatat
    10321 gacgaagatc gttatatctt gcttctttat ataggtagtt tttcataaat acaaatttgt
    10381 tattctctca tgattatcag ggtatatttt tatttattat gtcggtgttc caggaagtgt
    10441 tttaatttaa taacgaagaa attaattgtt tgtagaatga aggaaactat ttattgggta
    10501 gatgaatcac cacgaatagt caaaaggaga tttcaggata tgccaaaaat gaaaaaaatc
    10561 attttagcag taatgttatt ttctacggtt atatctttta cagccccttt tttgcttact
    10621 taagctgatt ttaagttttg gcccttagtc tggatctacg aggtgagagt caagaatgaa
    10681 aaaaataatt ggagcttttg tatttgcaat cattatcatt attatctgtt ttcaaataga
    10741 tgtttttggt caaaaaaaga tagttggaca aacggtcagc agtacgaaca gtacggttac
    10801 aaagacaaag gaatcatttg atgatacaga acaagagaca ttaatcaaaa tcggaaaaaa
    10861 tgaccgtaca ctatatacag atgactcgct aactacccca cttgcaacta taaacggcgg
    10921 agagctggcg gagtttcttt ctgaaacaaa aaatgcttat cagatcaaga caaatgatgg
    10981 ctatactgga tatttagccc tcgaagatgg aaccaaagtc acaaagaata tacaaacaaa
    11041 accggaagag ctatctgatg cagtgattgt attagatcct gggcatggcg gaaatgatac
    11101 tggggcatta agcaatgatg aacaaacaga agaaaaagat ataacattaa gtacagccat
    11161 aaaagtaaaa aaggcgctag aggatgctgg agcaacggtt tatttgaccc atactacaga
    11221 tgaattagta cagcttggag atatatgcga ctacagtgaa gaaaaaaagg cagatgtctt
    11281 tatcagttta cacgcagact ctacggaata tgcgaatgaa gcaactggaa tcacgacata
    11341 ttattactat ggacaagagg aaacattagc acagacaatt gctgactcct tcactgatct
    11401 gcctctggat tcaagaggaa tctccactgg gaactatcaa gttcttcgag aaaatcttca
    11461 accttctatt ttaatcgaga tgggttatat gaataatgat agtgatttaa aggaattagt
    11521 aacagacagt tatcagcagc agattgctgc aagtttgaca caagcattga ccacttattt
    11581 tcagtaataa ataagcccag ccaaacaaaa atagctcctc atatttttcg tttggccggg
    11641 cttattatcg cagatgcaag cttttaaaca ccgtttaagg aagaggtcgt gagcctgccg
    11701 ttcaactctg agtcacaagg agcaatttca aaaaacagct tctcatgttt gatgactatt
    11761 gtgacttgtg accgaggagt tggcatgaga acaccgttta agaaaaaggt tgtgaaatca
    11821 acgttttgtt ctgagtatta gagaaacaaa cggaaaaata gttcctcata ttttgccgtt
    11881 tgttgagcta ataccgagga tcagatgatt gaacaccgtt tattcggaac aagggactgt
    11941 gacatgactt ttgtcacagt tccattattt ttttagtagc ttcaaagctt tttctgtatt
    12001 ggcaaaatga agtttggcat atttttcaag cataggcatg ccgcctttct ccaatagttt
    12061 tgccgctact tggtcagatt tcgttccagc tcctgacgga agggtgattc cagcttcagc
    12121 tgatgctttg tctaactctt ccaaaaagct ggcacgactg atgatagaag cagcagcaac
    12181 agctaaatga tattgttctc ctttagtaac gaagtacagt ttttcttgta attgattttt
    12241 ttctaaacgc gcatattttt taaaatttgc ttccggcgta aactgatcga tcaaaatcgc
    12301 ttctggtttt tctggctcga ttttttttag cagcaaatgg atcgcttgat tgtgcaaagc
    12361 gactttcatc cgaacggcat tgtattttgg ttggatctca ttgtattttt ctggagataa
    12421 gacaagcagt ttatagggga tggttttttt taagatgtca gcaagctgga tgatttggct
    12481 atcttttaac tcttttgaat ctctaacacc aagtttacgt aattctgcaa gctgatcacg
    12541 tttcacataa gcagcacata ctgttagcgg accgaaatag ctgccatttc cgacctcatc
    12601 actacctaaa acggataatt gactgatatt ttttggcaaa gaagaggctg tttttgctgg
    12661 cttggcttgt ttatcctgtg cctcccccca tttatcagct tctattgctg cattcgtacc
    12721 ttgaaacatc acttttccgg atgtataagc ggtaatggtc gtcccgtctt tttttgcagc
    12781 aaagctagta taaggaatct gtttatttaa caaataagag cgatagtatg ctttcatttg
    12841 actaagttgg tcgtttgttg ctttgataat gacgttgctc ataaaattct cctcgttttt
    12901 atacataaaa ctataccgca actcacgact tttcgttttc taagagattg cgagacatag
    12961 cattttttta aagtttatca tataatagtt aagtatgtga aaaatatttg tggagaacgg
    13021 tgaaagaacc aacttcatgg tacactaaat aaaactttca tcaaatagga ggaaatgatt
    13081 cgtatggcgc acgaaaaaac acgctacaaa gcggtgattg ccaaccaaac atatactatt
    13141 atcggacggg aaaccaagca tcatatggat atcgtaacga agctgatcaa tgaacagtta
    13201 gcagaattga aacaattatc accacaaatg gataatgaac aagcagcaat cttgatggct
    13261 gtcaatgcgc tttcggatca attgaagaaa caagaaagaa tattggagct ggaagaagaa
    13321 acagcagaat taaagaaaaa aatgatcaaa tttacagagc ttgaaaatcg tgtgaaacgc
    13381 attgaagcaa tcgagaacga agctcgggaa gtattgaaag aaaatggtca agcagatcat
    13441 accattaaaa atcatgtgga agcacaacag attttaaacg agaaacgaaa aggacaaatt
    13501 aaacaaaaat cttctaatta agatcctttt atcaaaataa gaaaaattta aaaaagttag
    13561 aagagaaagg aacgtagcat gctgagtttg ctgattttat ttttattgct aattgcgttt
    13621 ttttctggag cacgtcgcgg gtttgctttg caaatcatat tcgcgattgg atatgtattg
    13681 tcatttattg ctgcccagca tttttacaaa ccattagcaa gtcatttgga attatacatt
    13741 ccatacccag ctgtcacccc aacatcaaag ttagcatttt ttgatcaggt atttgccttt
    13801 cacctagatg aagcttttta tgcaggaact gcttttctga ttattttgct aattggctgg
    13861 ctgcttaccc gatttgtggg ggtttttgtc catggattga cgtatgtgcc gatcttgaga
    13921 caggtagact ggattgcagg aggcatcctg tcactaatca tggcttacgt tactatattt
    13981 ttgattttgc agttacttgc ctttgttcca ttagatgtgg tccaaaatca attcggcgag
    14041 catagtttcg ctcgttttat cgttgagaga acgccatttc ttaccaacaa gatgtatgag
    14101 ctttgggtaa cgaatatttt gaattaagga aaatagtgct ggaaaatatt tcgttttttg
    14161 tacagagtag tttatttaag aaggctgcgt agcgtatgtc cggcacagct cttttttcat
    14221 agtgaaagat aaggtgataa aatgaataac cgaatccttg aaacattgga atttgaaaaa
    14281 gtcaaacaga tggtcagaca atttgtagtg actgcacaag gaaaagaaga actggcagaa
    14341 ttggtaccag tgagtgagaa acaaacgatc acaaactggc ttcaagaaac tgaggatgga
    14401 ttgaaagtgc aacgtctgcg aggcgggatc cctataccta aaattgaaaa tatccgtccc
    14461 catatgaaac ggattgagat cggagcagac ttgaatggag tggagcttgc acaagtttcc
    14521 agagtattgt ctacgacaag cgaattgaat cgtttcattg atgatctttc tgacagtgaa
    14581 atcgaatttg cacgtttgta tatgtgggca gatcagttag tcacgatccc tgttttgagc
    14641 cgccgtttaa aggaagcaat cgatgaagac ggacgcgtga ctgatgacgc ttctcctgag
    14701 ttaaagagca taagacagaa cattcggcga agtgaacaag ctgttcgtga acagttagat
    14761 gggatcgtcc gtgggaaaaa tgcaaagtat ttaagtgatg cgatcatcac catgcgaaat
    14821 gaccgctacg ttatcccagt caaacaagaa taccgcggtg tatttggcgg tgtagtccac
    14881 gatcaaagtg cttcaggtca gactttattt attgaaccaa aacaagtggt ggatttgaat
    14941 aatcgtttgc gtcaatacca aatcgctgaa cgaaatgaga ttcaacgtat tttaagtgaa
    15001 ctttctgctg aacttgttcc ccatcgtcaa gaaatcatcc acaatactta tgtgattggt
    15061 aaaatggatc tgatgaatgc aaaagcacga tttggtaaag aagtaaaagc catcgtgccg
    15121 ggaatcagtg aagacaatca tgtcgtcttg aaacaagcaa gacatccact gatcgatcag
    15181 gaaaaagtag tttctaatga catcacaatc ggaaaagact atcaagccat cgtcattaca
    15241 ggacctaaca caggtgggaa aacgatcacg ttgaagactt taggtctgtt acaactgatg
    15301 gggcaagcag gattaccgat tcctgcaggt gaagaaagtc aaatcggtat ttttgaggaa
    15361 gtatttgcgg atataggaga cgaacagtcg attgagcaaa gtctatcgac cttttcttct
    15421 catatgacga acactgtaga tattttatca aaagtcaatg aaaaaagtct ggtattattt
    15481 gacgagctcg gtgcaggaac agatccgcaa gaaggtgctg ctctagcaat cgcaatctta
    15541 gatgatcttg gtaaaaagtc tgcttatgtg atggcaacaa cgcattatcc tgaattgaaa
    15601 gtttatggat ataatcgggc aaatacgatt aatgccagca tggagtttga tgtggataca
    15661 ttaagtccaa cgtatcgttt gctgattggc gttcctggac gaagcaatgc gtttgaaatc
    15721 tctagccgat taggtcttga tacagaagtt attgatgaag cgaagcagtt gatgaatgat
    15781 gagagccaag atttaaacga aatgatcaca gatttagaga atcgccggaa aatggcagag
    15841 accgaatatc tggaaatgcg tcattttgtt tctgaggcac aagaacttca cgatgatttg
    15901 aaagaagctt acagctattt ctttgaagaa cgtgaaaaag aaatggaaaa agcaaagaaa
    15961 aaagcaaatg aagtcgtgtc agaggcggaa gaaaaagcag aaaaaatcat tgctgatatt
    16021 cgtaaaatgc aacagcagat tgggcaagga aatgtgaaag agcatcagtt gatcgatgca
    16081 aagacccaat tagcaaatct acatcaagaa gaaactttga agaaaaataa agtattgaag
    16141 aaggcgaaag aacaaaaaac gttgaaaccg ggagacgaag tgttggttac gacttacggc
    16201 caaagaggga cgcttttacg taaaaacggg aatcagtggc aagtagaaat cggtatatta
    16261 aaaatgaatg tgtccgaaga cgagctgacg cctgttgctc ctcaaaaaga gccgacacaa
    16321 cgagttatcc atgctgtacg atctgaatct agtagtcacg tgccgaatca attggacctt
    16381 cgaggaaaac gatacgaaga agcgctaagt gaggtagatc aatatttgga ttctgccatt
    16441 ctagctggtt atcctcaagt gactattgtc cacggaaaag gaacaggcgc acttcgcaag
    16501 ggaattactg attatcttaa aaaccatcgg agcgtcaaaa gctttgagtt tgcaccggca
    16561 aaccaaggcg gaaatggtgc gacaattgtt aaatttaagt aaagcttact aaaggtaagc
    16621 agatggttcg ctatccaagt atagaaatgc tatactagtc atagatttta aaaatggagg
    16681 tctttgatat gtcacaagta attacagata agacatttaa tgaagaaaca gataaaggac
    16741 ttgtattgat tgatttttgg gcaacttggt gtggtccatg tcgtatgcaa gcaccgattt
    16801 tggatcagtt ggaacaagaa tatgatgaag aagaattcag aattgctaaa atggatgtgg
    16861 atgaaaatcc agaaactcct caacaattcg gtatcatgag cattccaaca ttaatgttga
    16921 aaaaagatgg tcaagtagta gaaaaagctg ttggtgttca ttcaaaagaa caactacgtc
    16981 aaatgatcga tcaatattta taaaaactta cagcaaaaat aagctgaggg tgggactgaa
    17041 tccagttccg tcctcggttt ttttgcggtt gagttaaggt tattcaaatt aatatttttt
    17101 gagtataatt acgttgtcag gctggattgt ttttttgaca gacatgctat aataacttta
    17161 attgaatatg aaggggagta ccagatgaac gaacgaatca aaaacaaatt agctttactt
    17221 cctgatcagc ccggctgtta cttgatgaaa gataaaaatg gaacgatcat ttatgtcggc
    17281 aaagccaaaa tattaaaaaa tcgtgtccgc tcatatttta ctggtagcca taatacgaaa
    17341 acggaacggc ttgttagtga aatcgaagac tttgaataca tcgttacaga atcgaatatc
    17401 gaagcattgc tcttagagat caatctgata aagaaaaatg atcctaaata caacattatg
    17461 ttaaaggatg ataaaaccta tcctttcctt aagataacga atgaaaaata tccccgtttg
    17521 gtgattactc gtaaggtact aaaagacaaa gcactgtatt ttggaccata tcccgatgtc
    17581 ggtgcggcga atgagacaaa gaagatcctc gatcgattat ttcctctgag aaaatgcaaa
    17641 cctagtcaga cgaaggagcc ttgtctttac tatcatttgg gacaatgcct gtgtccttat
    17701 tatttcgacg tagatccgaa agtctatacg aaaatcgttg atgaagtgaa aaacttttta
    17761 aacggaggac acgaaaaaat cgagtcagag atccatcaga aaatggaaaa agctgctgaa
    17821 aacatggagt ttgaaaaagc tgcagaatac cgagaccaga tccgtgccat tgagacaatc
    17881 atgacttgcc aaaaaatgac aaatactgat ttactggatc gagatgtatt tggttatgcg
    17941 attgataaag gatggatgtg tgtccaagtg tttttcgtaa gacaaggaaa gctaattgaa
    18001 cgagatgttt caatgtttcc tttctataac gaagcagaag aagatttctt gacttacctc
    18061 ggtcagtttt atcaggaaaa tgagcatttc attcctaaag aagtcttgat tcctgatacg
    18121 atcgacaagc ccagtgtaga agctttgtta gctacgaaag tgctgcaacc aaaacgagga
    18181 gaaaagaaaa aattagttga attggcgagt aagaatgcct cagttgcttt gaatgaacgg
    18241 tttgatctga ttgccagaaa acaggaacgg acgatcggag cagttgaacg tttaggaaac
    18301 gcgatgaata tcccgacccc aatacgtatc gagtcttttg ataactctaa tatcatgggg
    18361 acgaatcctg tggctgcgat ggtcgtattc attgatggaa aaccggcaag aaaagaatat
    18421 cggaaatata aaataaaaac agtcaacgga ccggatgatt atgcatcaat gagagaagtc
    18481 atctatcgca gatattcgcg agtgattcgc gaagggttgc ctttacctga tttgatcttg
    18541 atcgatggag gaaaaggaca agtagatgtg gcaaaagatg tcttagaaaa tcaattagga
    18601 atcgatattc ctattgctgg catggtaaaa aacgataaac ataaaacaaa tgagttgcta
    18661 ttcggtacag atttggctgt agtaccgctt gagcgaaatt caccagagtt tttcttactc
    18721 cagcgaatcc aagatgaagt ccatcgattc gcaatcactt tccatcggca gctacgcagt
    18781 aaaaacagtt ttgcttcccg attagatgaa attgaagggt taggaccaaa acgaaaaaaa
    18841 atgctgctta aagagttcaa atcgttgaaa aatatcacag cagccacgac agaagaatta
    18901 caagaaatcg gactgccgaa aaatgtcgca caaaacgtat ttgataaatt acatcaggaa
    18961 tgaggaaagg gcactttaca aagaaagtaa agtgtcctat cattttatgt acaacaaaaa
    19021 gagcgtttac gttttgttgg taaataataa atcgcttacg tctggtgtct aaggatatat
    19081 gtgatttctt gaagaaggag tgaagaaatg ttagaagtca aggatcttgt taaaactttt
    19141 gggaactaca cagctgtcga tcatgtctct ttccaaatcc ccgatggaaa aatcatgggg
    19201 ctaattggcc aaaacggggc tgggaagaca acgacttttc gtttgatctt ggattttttg
    19261 acacaagacc aaggagaagt gttatggaat ggccatcatc ttggggagaa agattatgat
    19321 gtcatcggtt atcttccgga ggaacgggga ctttatccga aagtaacgat tcaagaccaa
    19381 ctgctttatt ttgcagaact tagagggaaa tcaagaaaag agattgaacc aaaaatcgac
    19441 ttttggatgg aaaaatttca ggtaaaaggg aaaaagacgg ataaagtaaa atctttgtct
    19501 aaaggaaatc agcaaaaagt ccagctgatc gccacgttaa tccatgaacc taaattgatc
    19561 attttggatg agccattcag cgggttagat ccggtaaatg ctgaattgct aaaagatgga
    19621 atattggaat tgaaaaaaca tggttcatgt gtcatttttt ctagccacaa tatggataat
    19681 gtagaaaaaa tctgcgatca tttgatcatg ttgcgaaacg gaaaaatggt tttgaatgga
    19741 aaagtacatg agattcgtga atcatttggc cgtacgaagt tattcttgga atctggttta
    19801 agccaacagg aagtagaaga aatcgaaggc gtgaaaaaag tgatccttca tgaagacaat
    19861 acgttagaga ttaccttaga agatcctgaa gctgggaaag aaatctttac tcgtgcgact
    19921 cagttcggct acattcctat gtttaaccag caaccgccaa ctttggaaga gattttcaaa
    19981 ttgaaagcag gtgaaatcga tgcgtaagtt ttggattatt accaaagatg tctatttaaa
    20041 aaatgttaag tcgatttctt tcttgatcat gatattagtc ccttttatca tgctgggtat
    20101 catttatgta gcaggaaact ttgctcaaca aaatagtgat gtcaataaaa tcggcgtatt
    20161 ggctgataat gagcaaatca gtcagcaaat gagccaagtc aaaacagatg attttgagtt
    20221 caaagcagtt gattctgaag aaaaagcaca aaaagagctt tcggaagaaa aaatcgatgc
    20281 gtatttagta gtctcaactg agaatgataa gataaatggg atgctttata gcgaaaattc
    20341 attaggacaa agtacacaac tactgataca acaacaactg actggcttgc aatcgatgct
    20401 tcgagcgagt caattaggca tttcaccaga agaagtagct agcttgagcc aacaagcaag
    20461 tttgactcga caaaaagtca attttgattc aaaaggaaaa atgacagtcg gagaagataa
    20521 ctcgacagtc caatacgtcg taagttatgt agcaacgatt gtcttgttca ttattatttt
    20581 gacgtatgcg cagatcattg cacaagagat cgcttctgaa aaaggcacgc ggatcatgga
    20641 agtgatcctg tccagtacga ctgcacaaaa gcatttttac ggaaaattaa caggtgtttt
    20701 acttgttgca ttaacgcaaa tggcattata cggtattatt tttggtatag gatacagtca
    20761 attcaaagat atggaaatgg tcaaaaatat attagacggt atctcattgg ataacttgat
    20821 tggaccattc ttgtggtatt ctcttctatt catgatcttt ggcattttga ttttttctgt
    20881 tttagcagct ttatgtggct ctttggtcaa caaagcagaa gatacagcaa aagcaatttt
    20941 gccagtgact tatctatctc taggcggata catgcttgga ttgatactag gagcttcaga
    21001 tccaaacaat atcgttattc ggatcacttc gtatattcca ttcttatctt catatattat
    21061 gccgattcgc ttagcaaatg agacagtcgg tatgggtgga gcattgattt ccttgttggt
    21121 acttgtagcc gtaacattct tattgatgat cttgtctgca aacatgtaca aatcgaatgt
    21181 actcgtttat agcgaaggcg gattatggag ttcattgaaa caatcgattt caattatgag
    21241 gaatgaacga aaaaaagcat aaaacaatcc taaaatacag aaggaagctg gacatctatt
    21301 gttcccagct tctttttgta tagacctatt ttatttattt tactatattg gatatatatt
    21361 cattgaaaat agtgtataac aactttataa tattgagtat accaattttt ggaggcgttt
    21421 taatggaccg ttatttagat ttactttcag aaaaattccc ctcaacggag gatgtcatca
    21481 cggaaatcat caatctcgaa gcaattttgc agcttccaaa aggaacagag ttatttttga
    21541 gtgatataca tggcgaattt cctgcttttg atcatattct gcgtatcggt tcaggaaatc
    21601 ttaaagaaaa gatcaaagac cttttttctg aacaaatgac ggaaacggat atcagccaat
    21661 tcactatttt tacggcttat ccagaatatg cattaacgac tgattggtac aaagaacaag
    21721 ataaatcgca gctgatccat catttgatcg atcttttacg gtttacgaca gtcaaatata
    21781 cccggtcaaa agttcgaaaa ggattgccga aagaatatag ctatatcatt gaggaactct
    21841 tgtatatcga tgaccgtatc aatggaaaaa aagactatgt aaaaaaaatc attgaacaac
    21901 ttgttttgat gaaggaagaa gaaaaatttt taacgaaact tgcacagacg atccaaaaat
    21961 ctgtcatcga tcatttgcat atcgttggag atatttttga ccgaggaact caagcagcca
    22021 aagtgatgga tcgaatcatg gatttttctt ctgtagatat ccaatgggga aatcatgata
    22081 ttttgtggat tggtgcgtat tgcggctctg aggcatgttt actgacactt ttacggattg
    22141 cagcacgcta taattattta tttgaattag agaaagaata tgggttgaat ttacgtccat
    22201 tgttttcttt tgctcatcaa acttatcaga agaatccagt atttgcgcct aaaaacagta
    22261 aaaatctatc cgaaagagag caagaagaat tagaaaaaat ccatcaggca ctttctatcc
    22321 ttcaattcaa atcagaacat cagttattgg atcgtcgacc tgaatttaaa atggacgatc
    22381 gtaaattgct ggaaaaaatc gactatgaag catcaacgat tgatttagaa ggtcagctct
    22441 atgagttgaa aggaacttgt tttcaaacga tccagccaga tgatccaaaa aaattcttgg
    22501 aagaggaaca aaaagtgatt gatagtttga tgtattcatt ccagcactct ttgagaatgc
    22561 aaaaacatat gacgtttttg atcgaaaaag ggggaatgta tctcacgaac aatcagcatg
    22621 tgctgtttca tggctgtata cctgtagacg agaagggaca gctcttagca tttgaattag
    22681 accaatctta tcgcggaaaa gaactgctgg gcttttttga aaaacagata actgaaagcg
    22741 caaaagatct gactgcaaaa gaagatttag caaccgattt gatttggtat gcgtggagtg
    22801 ggccattttc gcctttattc ggcaagagta aaatggcgac ttttgaacgt tattttctca
    22861 cagagcctca tacgcacgtc gagaaaagca atccttatta tcacttgcga gatgaagagt
    22921 ggttcagtga aaaaatttta gcagaattcg acacaaaaga agaagggtca gcaatcatta
    22981 atgggcacac gccagtaaaa gtaaaaaaag gggagtcacc gatcaaagca aatggaaaag
    23041 tatttgtcat tgacggaggt ttatccaaag cttatcaaaa aacgacagga attgccggtt
    23101 attcactatt atgcaattct tatggtttcc aaatcgtgac acattatccg tttttgccta
    23161 ttgaacaaca atttgcaaaa aaatccgacc aaacaaatgt gaaaaaagta atcgaacagc
    23221 aactaccacg caaactcaat cgtgatacaa caaaaggtat ggaactgcag cagcagatta
    23281 cccagctcaa aaggctgttg gactatcgaa aggacgattg agaagaattc cagtgaacat
    23341 tgttccatag actggagact gagacaaaag tcgtgtcgca gtctcttttt ccggataaac
    23401 ggtgttcttc tgccaactcc tcggtcacaa gtcacactat tcaacaaaca tgaaaagctg
    23461 ttttttgaaa ttgctccttg tgactcagag ttgaacggca ggctcacgac ctcttggtat
    23521 aaacggtgtt caaaagccag tttctcggta ttaagccaaa tttatgcaaa aatgtgaaaa
    23581 gccattttca caaaattttt cttaatactc gaaactaaac agctttttca caaccccctc
    23641 agaaagtcta ttaaaattca ttcacaaaga aatcgaataa gcgctgttca gatggatgta
    23701 cacggtgggt aagttccgga tgccattgaa caccgaggat tttatgcata tcatctttgc
    23761 tttgaaccgc ttcaacgagt ccatcgttag aaaaagcgat ggcttttaat aaaggtgaaa
    23821 gatctttgac tgcctgatga tggtaagaat tcacaaaata tggatcgggg agaaggttgc
    23881 ttaacaaact gtctgaaaca atcttgactt cgtgagtcgt aaattgcggg gcagtgggct
    23941 gttgttcatg ttttactgac cactttggat ataatgaaag atcttgataa agtgtacctt
    24001 ccaaaacgac attcaatagt tggagtcccc ggcagactgc aaaaattggt tttctttgtt
    24061 tcaatgcttc caagatcagt gcctgttcaa attggtctcg ttgaatattt gtttccgtta
    24121 gctttggatg aggatcttcc atgtaaagtt gtggactgac atcttgacca cctgcaagaa
    24181 taagtttgtc gatttgtcca atcagttgag gagctgaatc tggagacatg actggcagaa
    24241 taagaggcaa tccttgagca tctaaaactg catccacgaa tccttgcggt gtatagctca
    24301 cttgatttcc ttggaaagta tctgttgctc gaatcagttg atttccggca atgccgatga
    24361 ttggtttcat ttgtattccc cctaaagtag acttattgta acaaggattt aaaaaaaatt
    24421 aaactatgta agacttgccc ctatacttat ctgttcttgc tgtgttacta tctgtaaaga
    24481 gaaatttcgt gtgaaattca tgacgatagt tgaaaatatt gcttaatttg ttataataaa
    24541 aagtaagcag aaataaaaag gttgggcgta agcttcaagg atctagttct tcaaggggtg
    24601 agaaggacat tttattgaag gggcctgcct atactaagtt atctttagag gtacatactt
    24661 tcaatgaaaa aagaaagcat gtacctcttt tttaaatcga aaggaagtga agcaagtgtt
    24721 agaagctttg gaacaaatcc gaaaagcaga agaagaaaat gaaaagcgtg ctcaaacact
    24781 gcggcagcag ctgaagatct atgcaacaga aaaagagcag gaattggaaa cgatccaaac
    24841 aaactatcga caacaactaa aacagttggt ggaagaaaaa gaacaatttg aaatacaaga
    24901 attagaaaaa gaaaaaatga aattgaaagc agaagcagac aaggtgcaag caactttgaa
    24961 agatcaatat caaaagcatc agagtcaagc gatcggtgcg atcattgaaa gggtgaaaga
    25021 aacttatggc cgtcactaag atggaaaaag tgaccctcat ttcagataaa agaaatcagg
    25081 agaggatttt acaagcagta caaggaatcc aaaacgttga aatccgggat ctgtatcaaa
    25141 atagaacaaa caaccagtgg gtggagaagt attttccaga taccacgatt attgataaag
    25201 aagcaaaatt aagcgcttta ggtaatcggt tgaaagacat ccaagaagct atccaattca
    25261 tacaacacca cggcgatagc cgtcaaaaga aactccattt gaaacgtcaa gaactttcct
    25321 tacaagattt ggaagccaat tattccgaag aaaatttcat aaataaattg aaagaagtcc
    25381 ttgatttaaa agaaaagtgg gaacaactaa ctgaagaacg tgatcgttta gaagaagagg
    25441 aagaatggct tcttcattgg caacagctgg atattgctcc aagtatgtat gcaagtaaga
    25501 cgaccatttt tgagatgggg actgtgagtg cagcaaattt tgaaagtttc aaggaagaac
    25561 tgagtaagct tgatgacgtt tatatggaag aaatagatta tacgccaaaa caagtttatc
    25621 tttcgtatgt tgctttaaaa aaatcagttg ctgttataga agaaattgct gggaaatacg
    25681 ggttcaataa agaaacgtat ccttatgaac aaaatcctaa agaaaaactg caagagacca
    25741 agcagcaatt atccattgtt cacgagcagc aaaagaagat aacgacagcg ttaggtcagt
    25801 gcagtggcta tatccaagaa tttgaatggg tagaagaagt cacacttgcc gttgcagaac
    25861 gagaaaaaat aaaagaacgg tttatccatg cgacttatct gatcgttttg caaggttggg
    25921 tagatgcaga agaaaaacag aatttgctgc atgtgttaaa cgaaaccgta tcagaagaag
    25981 atatatacgt cagtttcgaa acaccaaact cagaagagat tcagcaggaa gtccctacta
    26041 aattgaaaaa ccatccgctt gtcgaacctt ttgaattgct gactgaaatg tacagtctgc
    26101 caaaatatga agaagtagat ccaacacctt ggatgacacc attttatctt gtcttcttcg
    26161 ggatgatggt cgcagatgtt ggttatggtt tgctgatgct cattgggaca atactagctc
    26221 aaaaactact tgttctacca cgcgggatga aacgtttcgt aaaattcttt gagattctct
    26281 cgataccatc gatcatctgg ggattgatct acagttcatt tttcggacag tcattaccaa
    26341 aagaactgtt tggcatccgc ttgcctttcc caatcctatc tacgacggat gacgtcaata
    26401 cgattttgat tttatccgtg attttcggtc tgatacagat tttggttgga ttatttgtgg
    26461 cagcaaagga aaatatcagg agaaaagatt acttgagtgc tgtcagtgat ggatttgcct
    26521 ggcaagggat cctaattggg atcgttattg cgttggttgg tgccatgttg ataaaaaata
    26581 cagcatttgt ttaccttggc gctgggctat cgatcattgc tgccttatgt atcttgatcg
    26641 ttccgattat ccaaacgccg tctaaagtca aaggtgctgc caaaggtgcg tataatcttt
    26701 acggactgac cggctatatc ggtgatttag tcagttatac acgtttgatg gcattgggta
    26761 tttcaggcgg aagtattgga gcggcattca atatgctagt tgctttcatg ccgccagctg
    26821 ctcgattcag tgtagggatc cttttgatca tcgctttaca cgcactgaat atgtttttga
    26881 cactgctaag tgcctatgtc catggcgcac gattgcagta tgtcgaattt tttgggaagt
    26941 tttatacagg aggcggacgt gcctttgatc cgctgaaaac ggcggaaaaa tacgtcaaca
    27001 tcaatcacaa gaaaaaaaac aataaataat tggaggattt ttatataatg atggattact
    27061 taattagtca aaatggtgga atggtatttg cggtattagc gatggcaaca gcgacgattt
    27121 tttcagggat cggttcagct aaaggtgttg gaatgacagg tgaggcagca gcagcattga
    27181 caacaagtca acccgaaaaa ttcgggcagg ctctgattct gcaattgctt ccaggcacgc
    27241 aaggtttgta tggattcgtt attgcctttt tgatttttat caacttagga aatgacatgt
    27301 cagttgtaca aggactgaac tttctaggtg cttctctgcc gattgctttt acaggcttgt
    27361 tttcaggtat tgcccaagga aaagtcgcag cggcaggtat tcaaatttta gcgaaaaaac
    27421 ctgaacatgc tacaaaagga atcatttttg ctgcgatggt tgaaacatac gcgattttag
    27481 gtttcgttat ttccttccta ttagtgttga atgcctaagc ataaaggagg aaaagcagat
    27541 gaacgccatt gaaaaaatca tctctcagat gaacgaagca gcagagcagg aaagagcggc
    27601 gttagaacaa gaagagcgaa tgaagatcga tcaaaacttt gaacaaaaac gtacgcaagt
    27661 tgaaacagaa catcaaaaac aaaaagaaaa acaaatcgaa ttactcgaaa aaaaataccg
    27721 tcagctaagg aatcgccagc aagtagaagt acgacaagaa aatttgaatg cgaagcagga
    27781 atttttaaga cgattgtttg cagatgcggt aactgaaatg gaaaattggg atgaatctga
    27841 acaaatccag tttatcaaaa atgcattgta ttcattacct ttgacaggaa aagtagcatt
    27901 cattgctgga gaaaaatcag cagcctatct ttctcagacg ttgttggatg aatggaacaa
    27961 tgaacttccc tttatgatgg ttttaagtga tgaaactgtt gctgatcaag cgggttttct
    28021 gataaacgat caaggagttc agtataattt tcttttcagc agccttgtac aagatatcca
    28081 aggaacgatg agttttgaga ttgccaatca attattcgaa taaggaggga tcagtgtatg
    28141 gaataccacg aactaaatcc cttgattcgc ggaagagagc ttgaactttt gtccaatgag
    28201 acatttgaac ggatgattca aacaaattct gtcgaagcac ttggtgaaat attgaaatcc
    28261 acgatttaca gtccatatat ttatgacgga tatgaatatg acttcgaaca gaatctttta
    28321 aaggagcaga gccgtctatt tcgctggtta aaggaatcag caccggagcc tgaaatcgtt
    28381 tggatctata cgatgcgtta tactttccat aatctgaagg ttttgacaaa agctgagatg
    28441 acaaatcaaa atctggacca tttgtatatc gacgatggat tttattcatt agaaaccttg
    28501 aaggatgcca ttcatacgca agtttcaaat gaacttcctg aaagcattat ggacagtata
    28561 cgagaagtac gtgattattt tgaagagtct accattcttc agggaattga cgtgatttat
    28621 gatcgacagt ttttgacaga gcagcgacgg cttgccgata agctaggata tcaagaattg
    28681 ctgacagaag tcattgcttt tattgacttg accaatatca caacgatggc tcgaggaata
    28741 ttgcagaaaa gaacatatgg gttcatgacg acggtacttt ccagctcggg aagtatcgaa
    28801 aaagaagtat ttttgaactt tgtagataaa gatatggaag attacacgaa ttttctatta
    28861 gagacagatt atgctgattt tctgcgccct gtcatccgtg agggaaatat tgatctcgta
    28921 aagcttgaac agttgaaaga tgattatcta agttcattgt atcaagaagc acaaacccag
    28981 gctttcggac cactgccact actagccttt ttgaacgcaa aagaggtaga aagcaaaaac
    29041 cttcgtttac tggttatcgg caaaagaagc catttcgaat cagaaacaat cagaaagcgg
    29101 gtgagacaag tctatgacgc ataagatcgg tgtagttggc gacaaagatt ctgttttgcc
    29161 attcaaattg tttggctttg atgttcgtta tggtacaacc aagcaaaccg ttcgtcaggc
    29221 aattgaagaa atggcaaaga atgagtatgg cgtgatttat gtcacagagc aatgtgcagc
    29281 attgagccca gaaacgatcg aacgttacaa ggaacaaatg atacctgcta tcgtattgat
    29341 tcccaatcat caaggatcat tagggatagg gctggaagaa attcaaaaaa acgtagaaaa
    29401 agcagtaggt caaaatatct tatagtatga aaaggagata gaaattttgc aaattggaaa
    29461 aatcataaaa gtctccggac ctcttgtaat ggctgagaac atgtctgatg ccagtatcca
    29521 agacatgtgt ctagtgggag atctaggagt tatcggagaa attatcgaga tgcgtggcga
    29581 tgtggcgtct attcaagtat atgaagagac ttctggaatt ggtccaggcg aaccggttcg
    29641 ctctactggt gaagctttat ctgttgaatt aggaccaggg atcatttcac aaatgtttga
    29701 cggaatccaa cggccattag atacctttat ggaaatcaca caaagtaatt tcttagggcg
    29761 cggagttcaa ttgcccgcat tggaccatga gaaaaaatgg tggttcgaac caacagtaga
    29821 agccggagaa acggtgagtg ctggagatgt tatcgggatc gtagaagaaa caaaagttat
    29881 aaaacataaa atcatggtgc caaatgggat aaaaggaacg atcaaaacaa tcgaaaaagg
    29941 ttcattcact attgatgaaa cagtatgtgt cattgaaacc gaaaatggtg acaaaaattt
    30001 gacgatgctt caaaaatggc cagtaagacg tagtcggcca atcaaagaaa aattaaaccc
    30061 ggatgcaccc atgatcactg gacagcgagt gattgataca ttcttcccag tgacaaaagg
    30121 aggagcagca gctgtacctg gtccttttgg tgcagggaaa acagtcgttc agcatcaaat
    30181 tgcaaaatgg gccgatgtgg acatggttgt ctatgtggga tgtggcgagc gtggaaatga
    30241 gatgacggat gttttaaatg aattccctga attgattgac cctaatacag gagaatcgtt
    30301 gatggaacgt acggtattga ttgctaatac atcaaacatg ccagtagcag ctcgagaagc
    30361 ttctatctat acgggaatca caattgcgga atatttccgt gacatgggtt atgacgttgc
    30421 tatcatggca gactccactt cacgatgggc agaagcactt cgtgagatga gcggacgttt
    30481 ggaagaaatg cctggtgatg aaggttatcc agcttatctt ggttcacggc ttgcggaata
    30541 ctatgaacga tctggaagag tcattgcatt aggatcagaa ggtcgcgaag gaagtataac
    30601 cgcaatcagt gctgtatccc cgtctggagg ggatatttcg gaaccagtca cacaaaatac
    30661 attgcgggtc gtaaaagtat tctggggtct tgattccagt ttagcccaaa aaagacattt
    30721 tccttcgatc gattggatac aaagctattc tctttattca acagaagtag ggaagtatat
    30781 ggatcatatc cttcaagctg actgggcatc catggtcacc gagggcatgc gtattttgca
    30841 ggaagaacag cagctgaatg aaatcgtgcg tttggtaggg attgattccc tttcagataa
    30901 tgaccgtctg acattagaag tggcaaaatc cattcgtgaa gattatttgc agcaaaatgc
    30961 ttttgatgat gtcgatacat tcacttcaag agagaaacaa ttcaaaatgt tgaagatgat
    31021 cttgaccttt ggtgaagaag gacgccgtgc gttgtcgtta ggtgcttatt taagtgagat
    31081 catggacggt accgtatcga ttcgtgaaag gatcggacga agcaaatata tcccggaaac
    31141 agaattagaa aaactagatc aaattattgg tgaaatcaag caaacgatgc aaacgatcgt
    31201 ttcagaagga ggcatgagca atgattaaag aatatcgtac gatcggtgaa gtcgtcggtc
    31261 cattgatggc ggttgaaaaa gttgctggtg tcaaatatga agaattaatc gaagtccgta
    31321 tgcaaaatgg cgagattcgt cgtggacaag tattggaagt ccaagaagat aaagcaatgg
    31381 tccaaatatt cgaaggaaca agtggtatca atttacgtga ctcttctgta cgatttttag
    31441 gccatccttt agaactaggt gtatcggaag acatgatcgg tcgagtattc gatggtttgg
    31501 gacgaccgaa agataacgga ccagagatcc tgcctgaaaa gcatttggat attaacggag
    31561 aagtaatcaa tccagtagct cgggattatc cagatgagtt tatccaaaca ggtatctctg
    31621 caatcgatca tttgaataca ttagttcgtg ggcaaaaatt accagtattt tctggctctg
    31681 gtcttcctca taaagaatta gctgctcaga tcgcgcgaca agcaacggta ctcgattcat
    31741 cagatgattt cgccgtagtc tttgctgcta ttggaatcac ttttgaagaa gctgaatttt
    31801 tcatggaaga ttttcgtcaa acgggcgcaa tcgaccgttc tgtcatgttt atgaatttag
    31861 caaacgaccc tgcaatcgaa cgtatcgcta ctcctcgtat ggctttgact gctgcagaat
    31921 atcttgctta tgaaaaggga atgcatgttt tggttatcat gacagacatg accaactatg
    31981 cagaggcatt gcgagagatt tctgcagcac ggcgagaagt tccaggaaga agaggatatc
    32041 ctgggtatct ttacacgaac ttagctactt tattcgaacg agcaggaaga atccgcggac
    32101 taaaaggatc ggttactcaa attccgattc taacaatgcc agaagacgat aaaactcatc
    32161 caatccctga cttgactggt tatattacag aaggacagat catcttgact agagagcttt
    32221 acaagagtgg gattcagcca ccaattgatg tactcccgtc tctttcgcgg ttaaaagata
    32281 agggaactgg acccggaaag acaagagaag accatgcagc tacgatgaat cagctttttg
    32341 cagcctatgc acaaggaaaa caggcaaaag aattagccgt agttttaggt gaatctgctt
    32401 tatctgatgt agacaagatc tatgcgaagt ttgctgagcg gtttgaaaaa gaatatgtca
    32461 atcaaggatt ctacacgaac cgttcgatta ctgaaacact tgatctaggg tgggaactgc
    32521 tatcgatgtt gccaagaacc gaattaaaac gaatcaaaga cgacatgctg gacaaatatc
    32581 tgccagaagg gaagtgagtt ctgatggcac gattgaatgt gaatccgacc cgcatggaat
    32641 tgactcgatt gaaaaaacag ttgacaactg ccacaagagg gcataaatta ttaaaagata
    32701 agcaagatga actgatgcgt caattcatcc tgttgattcg aaagaacaac cagctgcgtc
    32761 aagaaatgga agagtctatg acagaagcaa tgtctgattt tgtattggca aatgcttcga
    32821 tcacggaacc tttcatcgaa gaattatttg ttttgccggc ggaaaacgtt gatttgtcta
    32881 tcgtagacaa aaatatcatg agtgtaaaag tacctgtgat gaattttgaa tatgatgaac
    32941 agctgacaga cacacctttg gaatacgggt atttgaattc cagtgccgaa ctggatcggt
    33001 caatcgatcg gtttactacc ctgcttccaa aacttttgga actgacagaa atcgaaaaaa
    33061 cttgtcaact gatggcgagt gaaatcgaaa agacacgtcg gcgagtcaat gcattagaat
    33121 atatgacgat ccctcaatta gaagaaacga tctattatat tcgtatgaag ctggaagaaa
    33181 acgagcgcgc agaagtaaca aggttgatca aagtaaaaaa tatgggtacc actgactaag
    33241 tggtatcttt ttttaaaaga ggaaaacgat gattaaacaa agcaaacaaa taaagaaacg
    33301 tttgccggct gttcagcttc tcgcattagg attttttctc ctgattttag ttggcggcgg
    33361 cctacttacc ctaccatttt ttagtaatag tgggcatggg acaaatttta tcgatgcgct
    33421 tttcactgca acttctgctg tctgtgtaac gggattgaca acattgaata cagcagagca
    33481 ttggaacagt gctggtcaat ttttgatcat gcttttgatt gagatcggcg gtcttggttt
    33541 tatgatggtt ccgattctat gctttgcatt gataaagaag aaagtcagtc tcagcacacg
    33601 tattatatta aaagaagcgc tgaatctaga agaagtatca ggtgtgatga agctcatgct
    33661 ttacatccta aaattggcct ttgtgatcca attgattggt acggttgctt tatcttttgt
    33721 atttgtgcct gaatttggct ggttgaaagg tatctggtac agtttgttcc atgcaatctc
    33781 tagtttttgt aatgcagggt ttgatttgtt aggagacagt ttagccaatc accagcaaaa
    33841 tgtttatttg atcatggtgg tatctgcttt gatcatttct ggtgggttag gcttcatcgt
    33901 atggcgtgat ttactggaat atcatcagaa aaagaagatg acgattcatt caaaaatcgc
    33961 attaaccgtt acaggtaccc ttttattagg cggattcgtt gtgttctttt tcacagagcg
    34021 caatggggca acgctagtgg aagggaatat gtttcaacga ttggcaaaca ccttttttat
    34081 gagtgtgaca cctagaacgg ctggatatta ttcagttgat tacctccata tgagccatgc
    34141 aggtctgatt ttaacgatgt ttttgatgta catcggcgga acatctgggt cgacggccgg
    34201 cggattgaaa acaactacgt taggtgtgtt gctgatccag atgcgttcga tgttgaaagg
    34261 acgtacgaga gcggaagcat ttggccgtac catccgacaa ggcgcagtgt tgcgggcact
    34321 tactttattt tttgttacgt tgacgttgtg tgtagtcgcc atcatgattt tatcggtgac
    34381 tgaaacgata cctaaaactt ctggcatcga atatattgct tttgaggtct tctctgcgtt
    34441 tggtacagta ggtcttacga tgggattgac gccagacttg actgcaatag ggaaattgat
    34501 cattatagcg cttatgtaca ttggacgagt tggtgtattg actgtggtct tctctctgat
    34561 gacaaaagca caaagaacac aatcaaaata caaatatcca gaagaaagtg tcatgattgg
    34621 ataatttcat cttctgacag aaacctagtg atttagtaaa ataagaaaat aaaataattt
    34681 ttcttgcttc ttggatactt taagtgcaaa atgttcgttt attttttgag gcactacccg
    34741 ttgttgaacc tcgggtagtg cctctttttt attgaaagga atcaataaga tttgattcct
    34801 ttatttatca ataggttata attcatattt ttttattttt tcttttacga tacttagtcc
    34861 agaagctaaa atttcaaggt tattagagga tagggaaatt cgaacgaatg catctggttg
    34921 cgcacgtgta gtaaagcgtc tggaatgata aagtcggata ccgttagcaa gaaagtcatt
    34981 ctcaattatc ttagggtcaa tctcaggatc aactggaaga attcgatagt aagggacacg
    35041 attcgttggt ttttctactt tgaaaagaga atcaaaaagc tgattggctc tttttgtaag
    35101 acttaattta gtttctaaga tcctatttgc ttcatttgaa tggaggattt gagtgatgac
    35161 ttccacatct aatccagaag ttttcacatt tatattaaaa attgcttgtt ctatcttgct
    35221 ttggacatgt actggaacta caagataagc aactcgcaat ccagaacaaa taaattttgt
    35281 cattccagct aagtagattg tttggttagg taataaattt tggaaaggag gaatgatcgt
    35341 atgttgatag taagttgtta aaaatgaatg gatatcatct tcaataaccc atagaccttc
    35401 tttttcaatc acttcggcta attgctctcg tcttttgtga gagatttgaa accctatagg
    35461 attattacaa gaaggcataa gaaagacacc atgaatcttc ttttttctac attcctgaat
    35521 caatatatca ggtcgcattc cttgctcgtc aaaatcaatt ggaacgatct ctaaatgata
    35581 taactgagcc aattcaatga aattagcgta tgtatatcgg tctgttgcta ttctatcacc
    35641 tggagagaaa agtgcagaaa gtgtgatagc caatccattt tgaacaccgg aaacaataga
    35701 tagagattct aaggacggaa tgactccttg agtttttaac caatttgctg cagtagtcaa
    35761 ttgaaaattt gtgcctttgg gatcttggta attaagcaaa ccaacaagat ttgggttatt
    35821 actagttgat tgaataaacg ggacaacgaa tttattacat tcttcaaaag aactaaccag
    35881 accaaaatca atgatatgtt cggttacttc attggtagag atggtgatgg actcaaagac
    35941 attgggagaa ataaatgtgc cacttccaat attcgtatac agcaaacctt tctcaattcc
    36001 atatttataa gccttgccaa cggtagtaaa atttaaatct aaataatcag ctagctctct
    36061 ttgggagggt aactgagtgt ttttctgtaa tttattcttt aaaatatctt gttctaattg
    36121 ttgaatcaac gatcgataat aaggacgctt caatttttgt ttgtctggtc gccaagttaa
    36181 cgggtaattg tcataagaat taataggcat tttctccact ccttaaaatt gtataccata
    36241 caattttacc attgattgta ttgattttag aagttaatct tttgtgagga gggaattgtc
    36301 tatgaaaatt attaattttg aggaagtagt agcttctttt agttttgaag aagcgattca
    36361 agtaatgaaa aaatgttttt ttgattatga aagtggtaaa atcagccaaa atcctcgatt
    36421 ggtggaaatt ttacctgacg gaaaaggcaa aaatatgttt gcgatgatgc ctgcttattt
    36481 gggggagaac agatattttg gcacaaaagt cattaccgct tttccggata atcatcagta
    36541 tcatttacct tctcatttag gagagatttt cttgtttgat gctcaaaacg gactacccaa
    36601 agcattgata aacgcaaatg cagtcacctg gattcgaaca gctgctgtat ctgcgctggc
    36661 aacagattac ttagcaaatc cgcatgcaga aacacttgct ttaattggag ctggtcaaca
    36721 agcattgtcg catttgactg cgatttctac cattcgtccc atcactacag tgtttgttta
    36781 cgatatttta gaagaaagac gaaatacttt tatcgctaaa gctaaaaaac agtatcctaa
    36841 aataacgttt ataaatgcaa tatcagtaga agatgcagta cgtccagcgg aaatcatttg
    36901 tacgttgacc tctagtaaag aggcatttct tcaaaaagag tgggtaaggg aagacgcaca
    36961 tatcaatgct gtgggcacat ttactcctga tacaagagag ataagtacat cgttgatgga
    37021 aacttctcaa atctatgtag atgattactc agctgcctta acagaaagcg gggacctgct
    37081 tatagccatg gcagaaggag atttagagga atcttgtatt gttggtacat taggcgaatt
    37141 agtttctgag aaaaaaacat tttataaagg agaatcgagg ccgacgattt tcgacgcagt
    37201 tggtctagct attgaagatc tttgttgtgc agaatatatt tataacaaat tagagaaagg
    37261 ggctttaaaa tgaacttaga ttattacgta gttgatgcat ttgcagatga ggtgttcaaa
    37321 ggaaatccag cagcggttta tgtgctagaa gaatggctgc cagaaggtac gatgcaaaaa
    37381 attgccattg aaaacaattt atctgaaaca gcatttacag tgaagaaaaa ccaagaattt
    37441 gagcttagat ggtttacgcc agatcgagaa atcgatcttt gtggtcacgc gacattagca
    37501 acagcatttg ttttatttaa ctattacaaa atacctgatg aaacgattaa attttctact
    37561 caaagcggta atctatttgt gacaagaatt aaagattatt attacatgga ttttcctagt
    37621 attatgccga aaaaagtgcc gatattgtct gaatatgaag aagcgattgg ggctaagatt
    37681 aaagaagcct acttagcacg tgatttattt ttcgtattag aagatgaaaa aacggtggct
    37741 aaattgcagc cagattttac agctatcaaa aattttgaat taggaatagg agtcatcgtg
    37801 acagcagaaa gtgtgcaaaa agactttgtt tctagaacct tctttccaaa attaacaatc
    37861 aatgaagatc cagtatgtgg atcagcacat tctaatctta ttccttattg ggcagaaaga
    37921 atgaataaaa caaaattgtc agcttatcaa atgtcatcaa ggggcgggga tctagaatgt
    37981 gaattaaaag aagatcgtgt gataatagga ggaaaagcag ttttgttttc taaaggtacc
    38041 tcgtttattt gatttctttc aaatgaatta aaaataaatt ggtggagagt ggcaacctta
    38101 tagctacaat ggttgttaaa aaaagacgca aactttttca atttaatgaa aagtttgcgt
    38161 ctcattttaa ttattggtgt ttgtttttta ttcaatcaag agtaaaatgc cccatactaa
    38221 ctatcctcgg atgacttcga ttttataacc atcagggtca atgacaaagt agtaagaagg
    38281 cgcagtgcca ggtaatcctt ttaagtcagt aatctcaaga ccagcagctt tatgttgctc
    38341 gtgtaatttt tctagatcat cagctgctat agcgatatga ccatagccgt ctcctagatc
    38401 atacgcacca tgatcatagt tgtaagtcaa ctctaattca tagtcatccc caggaagtgt
    38461 caaataaaca agtgtaaatt tgttttctgg aaaatcacgg cggcggcttt cttcaaaacc
    38521 aaatgccttt tgataaaatt cgattgatgc ttcaagatct ttcactcgaa cacatgtgtg
    38581 agccattttc atagattcat ctctcctttt ccttttactc aatcataaca aaaagaagta
    38641 aggaaatagt tgatttgtgc ttgttcatga gaaatttctc atgtaaaatg gatagaaaat
    38701 aaaactgtta aggtggaaac tattcatgga taaaccaatt tttggtgaaa aaaagcaatt
    38761 tgctgattat caaacccgtt atgcagcata tattgtcata gaaagagatc agcagattgc
    38821 agtaatcgag gctccaaatg gtgctttttt tcttcctggc ggggaaattg aaggagaaga
    38881 gacgaaagaa gaagcgattg tccgtgagct gatagaagaa atgggaattg tggcagaaat
    38941 ttcttcttat ctgggagaag ctgatgagta tttttactcg aattatcgtg caacttatta
    39001 ttataatcca ggatatttct ttgttgctga ttcttggaag cgtataggag aaccaactga
    39061 aaagaccaat aaaatttggt gggtgagccc tcaagaagcg cttgtgaaat tgaaacgtgg
    39121 tagccaccga tgggcagtcg agagatggat cgaaaaaaat aaaaactgaa agaaagcgag
    39181 tagatcagct ttctctcagt ttttttattt attacagtac atattttttg attgcttcag
    39241 ctacaccgtg ctcgtcgttt gatgaagtga tgacatttgc tgcttctttg acaagagaaa
    39301 cggcatttcc cattgctact cctagaccag catattcaat catggataag tcgttctcgt
    39361 tatctccgat agccatgatt tcatcttgat caataccaag gtgctgtgcg agattcgcaa
    39421 ctgccgcacc tttacttgct tctttattta gtacttcgaa gtaatagggc gcacttttga
    39481 ccgttgtgta tttatcacgg aaagtttgcg gtaaacgcgc aattgctgca tctaaaattt
    39541 ctggttcgtc gatcatcatc attttgacga tgttcatgtc tggtgtcatt tcttcaggtg
    39601 ttcgatattt tagcggcatc ttgactaaac ttgcttcgtg gatcgtataa gcgctgatat
    39661 ctcgattagg cgtgtagatc gctttgtcat cgatcgaatg gagatgactg ccgacacggc
    39721 gtgccattac ttcgatctct aggaaatctt catgtgtcag tccgtgacgg gcgatgattt
    39781 tacctgattt cgtttgttgt acgagtgccc cgttataagt aataacgtaa tcattatctt
    39841 gaaaaaggtt caactcgttt aactgttcct ggacacctgg taagggacgg ccagtgcata
    39901 aaacgatcga aacacctttt gcaacagcag cggcaatcgc ttcttttact tcttttgtta
    39961 cttctctttt ctcatttaat aaagtaccat cgatgtcgat agcgactagt ttgatagaca
    40021 taatttcctc caatatattt taatttattt caatcaatgc gccattacgg atatggctgg
    40081 caaattcttg ataagtttcg tcaaataaat cataatgatc acgcaaggac ggatcaacca
    40141 tttcttttgg aaagaaaaat cgctcatctc cttgttcttg tcccgctaat gcagcaacaa
    40201 gctgactaac ctgtgataat tctatcaaag ttccgtcatt tcgcaaaatc tcgatttgtg
    40261 tgcgatgtct gccttgttct gggcgataaa aatcataagg tagatcgtag ctagaattca
    40321 cagcagtgta ataaacagga ttatatccga ccttttctac taacaaagtg agttcttgga
    40381 ctaattttga atcccggttg ccagaaaaag tagcagattt cagtggttta cgattcaaaa
    40441 aacgtttagc taaatcattt aaaataggat cagcagattc agaccattga gtaaagtaag
    40501 tgcccaagac cccatcatca agtttgaggt attcttctaa agtaaagctt ccgtcaagaa
    40561 atggcagaag taattgagaa tggagttcaa aactgctggc atcttcttga tacaactcgt
    40621 gtgcgcgatg aagcagatgc tccaaaatta cttccatacc acgggaaaca ggatggaagt
    40681 acacttgcac atacatttga tatcggctaa cgatataatc ttccactgca tgcatgccac
    40741 tcatggaaaa agcgatcccg ccttcataag gacgaatcac acgtaatatt cgggtaagat
    40801 caaatgttcc atattctgtt ccagtgaaat aagcatcccg aagcaaatag tccattcgat
    40861 ctgcatcgat ctgactagaa atcatttgga caacttgtgg gttggggtaa gttttttgga
    40921 tcacactagc taccttttca ggaaaacctt cttctactcg gttaagaatc tgatacactt
    40981 ctgtttctgg agaagtgatg atctctacag tgatggcttc atgattcgta tggaagatat
    41041 gttcaaatgt atgagagtaa ggaccatgac cgacatcatg caacagtgcc gcacataaag
    41101 tcaccagccg ttcctgatca tcccagcctc cgttgcctat tttttctttt gaaaaatttc
    41161 gagaaaagat atcgcagatt cgtcttgaaa tctcataaac gcctaatgaa tgagtaaaac
    41221 ggctatgttc tgctccgtga aaagtgaaag aagaagtgcc taattgttta atgcgtcgta
    41281 gacgttggac ttctttcgaa ttgatcaaat ctaagattac ttgatgctgg acatggatat
    41341 agttatggac tggatcacga aaaacttttt ccataggcag catttgatat ttataagggg
    41401 ttgtcataat gtagctcctt tatgttatta cgttgttcca ttctctggat ttggttgttc
    41461 cattgctcca gctggatttc tttttttagc cagtcggtag aatcctgtaa atcacttgca
    41521 gaatacagct tttcaaaagc ttttgcaaat gcttctttga cttcttttac aaaaaggggt
    41581 tggtcaagca gttcttcaag tgttgccatt gtagcaggat ccactgcagg atagccattt
    41641 gtaccaaagt cttcttttaa agcagattga taaaatcgct tcatgacttg cccacgtttt
    41701 tcctgattac cgttgacact taagtacatc ataacagaaa tcccattttt gatccgacgc
    41761 tgagcgatac cggcaaattt tttgccatgg atgcttaaat cataagttcc aggacaataa
    41821 gaatgggtga tttcgaatgc ttgtatcggt gcctttggaa aagcgtattt agtcaatagg
    41881 agcatttgct cgtaagcgtc atctatggtt attttttttg tgtcactttg ggggaaaatc
    41941 aaagaaatat tcaaaattcc ttcatctgat acgatcccta atccacctga atttctgatc
    42001 actggagcgt aacctgcatc ttccagtgtt tggatcccgt cacttagaaa aggagttcga
    42061 acatccttca tacctaagat gactgtgcag tcatattgcc agaaatgtaa aaagatttgc
    42121 tggtgttctt tagaatattc cgttaatata tctgttaatg caaaagggga aaagtcgttt
    42181 ttttgataaa tgtgctgatc tagtcgaatc gcagggttca ttcaaccggc tcctttgtat
    42241 aaattcatat tttctacaat attatactct aaaatcaaag agttgttttg gaaaaaaggt
    42301 tttctgtaaa aatggacaag ttggttgaca aaacaaaaga aactaggaac aatgtagcta
    42361 tgagaagtaa aggagaatga ataatggaat tatcacaagg aacaccgatt tcaatcaaat
    42421 tgcgtacaaa agtaaaacag caaggggaag tgcaagattt ttattttgat ttgaaagggc
    42481 aaatggtgac aattggcgat acgctgtaca tacgttataa agagattcag gaggagacgg
    42541 gcgatgagat tcctgtaacg atcaaattag ttccagatgg tcatgtacag ctgatccgtg
    42601 caggagaaat gcggatgcgt ttgaaatttg gctataaaga acggttagaa acatcctatc
    42661 gaacaccata cggtatgatc cagattgcta cttttacgaa agaactgcat gttagtttga
    42721 aagaccgtcc cacagcaggg aaggttcgaa tcgattatga tctgttcatg ggaccggaaa
    42781 aaatcggcga atattatttg accttggatt ttacagcgta aatataaaag aaaagtttga
    42841 ttttttgtgt ctgattttgt atgataagga gtagactgtg aaaggacgtg tcctgattgg
    42901 aaattagtgt atttgaaggt gcaaacaaaa gcgaattatc aatgatcgaa gtagcacacg
    42961 cgatcttaga acaacgtggc gatgtcatgg atttttctga tttagctaac cagatccaaa
    43021 actatcttgg gaaatcagac agtgaaattc gtgattcact cgcacaattt tatactgact
    43081 tgaatattga cggcagcttt atctcattag gggataatcg ttggggcttg cgttcatggt
    43141 atgctatcga ttcgatcgat gaagaagtaa accatggaat ggacgaagag gatgaagata
    43201 ctccacgtcg ccgtaaacgc aagaaagtca acgcctttat caatgatgat gaagacgcga
    43261 tcgattacaa tgacgatgac ccagaagata cagatctgac agaagaagat gacgatgatc
    43321 tgtttgatga cgatgatgat gaagatgaag aaatcgctgc ttataattct gacttgcaag
    43381 aaatcggagc agatgacccg acagatgatg aagaagactt gccaggaaat atcgaagaag
    43441 atttaagtat catagacgaa gacgatgatg atgaagatta tgaagaggaa gaattttctg
    43501 actctgaaaa agaataaaca ttattttctt acgagaggtt gtgacagaga cgatcagcct
    43561 atcagaataa ggaggtgtga cacgattttt gtcacacctt cttttttgta tataaaaatc
    43621 ccaagtaaat acataaaaaa taaaaaaatt gaaactttta gcgcaccttg tacgtcatat
    43681 taagtgaggc agaaaggagt ggagaatgat ttttactgga tataagaaaa aacggcagat
    43741 cgaaaaatac cgtcacctgc tgaatggact catcgaaact gattatcaaa aaatgttccg
    43801 tatcacgatg aattacgtac atgataaaga agaggcctta gatgtgatgc aagatagttt
    43861 tcataaagcc ctgaactatt ttgaaaaaga aaaagagatc gagcatttta gtgcatggtt
    43921 ttatcggata ttgatccgca cggcattaga tagttggcgc agacaaaaaa ggacgcctgt
    43981 ggacttattt gaaattcaag atatccccca acagttacct ttagaaactt ccgttgcaga
    44041 gctccatatg attttagata aaatagacag tccggaaaaa gagattctga tcctctactt
    44101 ttttgaagga tttcgtttga aagaaattgc gactatcttg gatatgaatg aaaacacagt
    44161 taaaacgaaa atgtaccgct cattgaatgc tttacgtcaa atcctagaat gaaggagaga
    44221 agagtgccat gtattcccaa aaagaaaatt taaaaaaact aaagaaaact tataaagaac
    44281 aagcaattcc caaagggctt aaagaggaga tccgccagcg ttttattatc gaagagcaat
    44341 catttataaa agcaaagcgg agaaagagac gtctccaagg gttcggagta tctttggcta
    44401 tcgtaatgat tacaacaagt agccttcttt ttaatagtca agttcgaagc tttgcagaag
    44461 atttacccat cttaggatca gtcattgaat tgatcttagg cgaacgcttt actgatcgat
    44521 ctgaaaaaat cgatattcag gtaccgaaga tcaatacaca aaatgagaaa gaaaataaaa
    44581 caattcatgg attaaatcaa aaatactttc gcgaaggaca agcagatttt gaaaaagctg
    44641 aaaaagaata tggaaatttt gaaacggatc attaccaagt tttgggagat tatcagaaaa
    44701 tcgtagacga taaccggttt ctcgtgattg aaaggcagat cacccaaaca gcagcagata
    44761 gccatgttga aaaaagatac gacacaatcg acaagaaaaa cagtgtccag ctctcacttc
    44821 cacttttatt caaagatgac acctatctat ctgttttgac aaaagaagtc aaacggcaga
    44881 tggccgaaca agtcaaggaa gatccatcta agtactattg gactgagcaa gatattcaag
    44941 aagggacgat agaaaaacca acacttgtta cgcctacacg aagtttttat ttgaacaaag
    45001 agcatcaatt agttttgact ttttctcaat acgaaattgc tcctggttat atgggtacac
    45061 cagaatttgt cattcctaag tccgtgacaa aaacgatttt ggcatcggaa gattatttgg
    45121 atcattagac gagaagtagt tgcgactagc agtttcaatt ttcaagtaag tacaagtaaa
    45181 taataagaag agaaaaagag aaagaagaga tatagtgaaa agaaattatt tagttatcag
    45241 tattattgct ttatccgtgc ttttgttttt cgaaattact tcggtggcct ccttgatcac
    45301 cgaagtaaaa ggacaaacac actcttcgga gcattcgtca caatctttca aacaatcaga
    45361 acaatcaacc attaaaagcc aatcaactga aacagctaac gtcaaagaag ccattcaaga
    45421 atcagcggaa aaggtacaaa gtcagtcatc acaatcaaca caagacagta caaaaacgag
    45481 ccgagatccg gctgtcaaaa gcgtcgcaat cagctttgat gatggaccag gagcgaccac
    45541 aacaccgcag cttctgcgaa tcttaaaaga aaaaaacgtg catgccactt ttttcgtctt
    45601 aggagaaaat acggcgcagc atcctgaaat cgtgaagcag acagctgaag cagggcacga
    45661 gattggcaat cacacatacg atcatcagaa tctggccact ctttctgccc agtcgatgac
    45721 ggaggaagtg acgaaagcag acactgagat caaaaaagtc actggcaaaa cccccacttt
    45781 tgttcgtccg ccctatggtt ctgtcacgaa tgtaggagca acgatcatcc agcgaccgat
    45841 catcgaatgg tctgttgatt cagaagattg gaagacaaga aatcctgatt tgattttgca
    45901 gaagatccaa gcaacagtat acgatggggc aattatttta ttccatgata tctatcctga
    45961 aacgattcgt gccgttcctc aagtgatcga ttatctgaaa gagcaagggt atcgcatcac
    46021 gacagttggg gatttattag ggcatccaac ggctgtcgag aactattatg gcagaaacga
    46081 tcatcggcca gttcagtaag tgagacaagt atctttaata aataacacat tttaataagt
    46141 agttgaacac ataactacct tacttgcaaa ggcttaacaa tatctataca ggtacaacaa
    46201 aaaactgtcc accaattttc tttggcggac agttttcact taaaaataaa gaagcaacta
    46261 ttcgtaaatt atgctaaaat agcagtagaa cgcgtcctga gggaatcgaa cccccgtctc
    46321 aagaaccgga atcttacgtg atatccacta cactaaggac gcaagcactg ggataattgt
    46381 aactaaacag ataaaaaatt acaaggggat tggacaaaaa aatgaaattt gagcaaaatt
    46441 tttcacaaaa acagcagcag acacagaaac tagccatgac gcaacagttg caacagtcca
    46501 tccaagtttt acaatataac agtgaggagc tgttggcatt cgttgagaat caagcaatgg
    46561 aaaatccatt ggtggaagtt gttgagccgg aatggcagcc agattacata aaagcttctt
    46621 catcttctta tgaaggagaa gagacaaatt acctaaatca gattcctgat acaaaagggt
    46681 ctttatttga ttcattgatc gaacaagtcc atttgaatta ccgagatact tttttgagga
    46741 aaatcgttct ttatcttgta gaatacatcg atttgaacgg atttttgacg attagtttag
    46801 aagaagccgg aaaagagatt ggagctacgc ctatccaaat gctcgatgcg ttgactctga
    46861 ttcagcaatt agaaccagct ggagtaggtg cacgtagttt gcaagaatgt ctcatgcttc
    46921 aaacagaacg agatgattat gcgccggaat tagcttatat cgtgttggaa gaatgttttg
    46981 aggaactggt ggagcgaaaa tggaaagaaa tcgcacaacg tttttctgtt gatctacatg
    47041 ctgttcagca gatattcgac tatttacaaa cgttgagtcc aagccctggc cggattttcg
    47101 accgtagcag cgaattgtac attattcctg atgtccgggt attagtggac gacgataaaa
    47161 atgtacaagt tatctcaaac cgaaaaaatc agccaaatat acgctttcaa gagagttact
    47221 tcaaacaaat gtcacaacaa gcagataaag aaactgaaaa ttatttaaaa gaacggaaac
    47281 aggaattcga atggttgaag aaaacgatcc tacaacgtgg ggatacaatt ttgcgggttg
    47341 ctcaagtcat tgtttcccgg caaaaagctt tctttatcga caaggaacgt ccaatcaagc
    47401 ctcttacgtt aaaggaagtt gcaactgaga tagatgtgca tgaatccacg gtcagtcgtg
    47461 cagtcaacgg gaaatatttg gaaacagact tcggtgtatt tgaattaaaa aaatttttca
    47521 ctacacgaat tcctacgaat agtacagaac agacagaaga cctttcagca gatacagcga
    47581 agaaaaagct gcaggaatta gtcgatcaag aagacaaaaa caagccgttg tctgaccaga
    47641 aattggttga attgctgaaa aaagatgaga tagcgatctc aagacgaaca gtagcaaaat
    47701 atcgtgattt attaggaatc ccgagttcat caaaaagaaa acgttatgat aactaatcag
    47761 tcaaaagact agaaaaagta tttcactttt tctagtcttt ttagttgaaa aacgagagca
    47821 aaactgttag acttacagtc gtgaggttga gatttccctt tattgatgtg aaattcgaat
    47881 agttaatttc tttttttatc gtatatgggt cgttttaagt ctacattgga cgtaaagtgt
    47941 ccaactaagg agatcgctat gctggatgaa ataaaaatga ttgaatctgt tgcaccagat
    48001 attatcgaag tgttgcaaga acgctataaa attttacgaa atatctattg gatgcagccg
    48061 attggacgtc gaagtttatc ggaaagtatg gggatcacag aacgagtatt gcgaacagaa
    48121 acagatcttt tgaaaaatct gaatttgatc gacacctcaa aaagcggtat gacgctgaca
    48181 actaagggcg aagaagttta tcaaagcctt gaaaacttca tggatcagct tttaggtacg
    48241 catcaaaccg aacaacagtt ggcagaatat tttggtaacc aacgctgtat cgttgtttca
    48301 ggaaacagcg aagagcagac caaagtggct gatgcattcg gcgaagcgct gagcgaagcc
    48361 ctagaccgac tacttccaga aggcgagaat atcatcgctg tgatgggagg aactactatg
    48421 gctgtggtag ccgaacaatt gtctaatctg gaaaataaga aacggcataa cctgtttgtc
    48481 cctgcaagag gcgggattgg tgaagcgata actgtacagg caaattctgt cagtgcaaga
    48541 atggctgcta aagcaaacgg taaccaccgt gcactttatg ttccggaaca attaagtctg
    48601 gcaacttaca attctttact caatgagcca tctatccaag aagtcttaaa cttgattagt
    48661 gaagcgaatt gtgttattca tagtattggg cgtgcattac acatggcagc acgtcgtaag
    48721 atgactgaaa aagaattagt catgctgaaa caagcaaatg ctgttgcgga atcttttggc
    48781 tactttttca atgaaaaagg tgaagtcgtt tataaggtcc ctagaatcgg catagaattg
    48841 caagatttgg aaaaagtccc gatcatcatg gcaatcgcgg gcggaaaatc aaaagctaaa
    48901 gcaattcgag cttatatgaa aaatgcacca aaacaaacgt ggctcatcac tgatgaagct
    48961 gctgcaaatg agattttaaa aggggtaacc ctttaaaata aatatttttt tgattttcat
    49021 aaggaggaaa tcttaaatga cagttaaagt aggtattaat ggttttggac gtattggacg
    49081 tctagcattc cgtcgtatcc aagatgtaga tggaatcgaa gtagtagcaa tcaacgactt
    49141 gacagatgct aaaatgttgg cacacttgtt aaaatacgac acaactcaag gacgtttcaa
    49201 cggaacagtt gaagttcatg aaggttcatt caacgtaaac ggaaaagaag ttaaagtatt
    49261 agctaaccgc aacccagaag aattaccatg gggcgaacta ggcgtagata tcgttctaga
    49321 atgtactggt ttcttcactt ctaaatcagc agctgaaaaa catttaacag ctggtgctaa
    49381 acgcgttgtt atctctgctc ctggcggaaa cgatgttcca acaatcgttt ataacacaaa
    49441 ccacgaaaca ttaactggta aagaaacagt tatctcaggt gcttcatgta ctactaactg
    49501 tttagctcct atggctaaaa cattgaacga caaatttggt gttgttgaag gattaatgac
    49561 aactatccac gcttacacag gtgaccaaat gactctagac ggacctcatc ctaaaggtga
    49621 cttccgccgt gcacgcgctg ctgctgcaaa catcgttcct aactcaacag gtgctgctaa
    49681 agctatcggt ttagtaattc ctgaattgaa cggtaaatta gacggagctg ctcaacgtgt
    49741 tcctgtacca acaggttcat taacagaatt agtaacagtt cttgaaaaag aagtaactgt
    49801 tgacgaaatc aatgcagcaa tgaaagaagc ttcaaacgaa tcttacggat acaacacaga
    49861 cgaaatcgtt tcttcagata tcgttggtat gacttacggt tcattatttg atgctacaca
    49921 aactaaagta atgacagttg gcgacaaaca attagttaaa actgttgctt ggtacgacaa
    49981 cgaaatgtca tacactgcac aattagtacg tactttagaa tacttcgcta acttataaga
    50041 tagacaaacg tacaagtgta aattatagac atgtacattt aaaagcgggg aagcaatcgc
    50101 gcttcttccg ctttttttga taataagttt attcaggagg aaataaaatg gctaagaaaa
    50161 cagtgaaaga tatcgattta aaagacaaaa aagttcttgt ccgtgttgac ttcaacgttc
    50221 ctttgaaaga cggcgtgatc actgacgaca ctcgtatcaa agcagcattg ccaacaatca
    50281 actacgttct agaacaaggc ggaaaagcaa tccttttctc tcaccttgga cgtgtaaaaa
    50341 cagaagaaga taaagaagga aaatctttag ctccagttgc aaaacgtcta ggcgaattat
    50401 taggtaaaga agtaacattc gtacctgaaa ctcgcggaga acaattagaa gaagcaatcc
    50461 gcaacatgaa tgacggcgac gttgtcgtat tcgaaaatac acgatttgaa gatattgacg
    50521 gtaaaaaaga aagcaaaaat gatacagaac taggtaaata ctgggcttca ttaggcgatg
    50581 tatttgttaa cgatgctttc ggtacagctc accgtgcaca tgcttctaac gtaggtatcg
    50641 cttcaactgg tatcccaaca gttgctggat tcttgatgga aaaagaaatc aagttcatcg
    50701 gtgaagcagt agaagaacca aaacgaccaa tgattgcaat ccttggtggc gcaaaagttt
    50761 ctgataaaat cggcgtaatc gaaaacttga ttcctaaagc agataaaatc ttgatcggtg
    50821 gcggaatgac ttacacattc tacgaagcaa aaggaatcaa gatcggtaac tctctagtag
    50881 aagctgataa agtggaacta gcaaaagaat taatcgaaaa agcaggcgac aaacttgtct
    50941 tgccaatcga caatgtctgt gcaccagaat tttcaaatga tgttgaaaca caagtaatcg
    51001 aaggagacat tcctgatggt ttgatggctt tagacatcgg cccagcatca gtaaaattat
    51061 ttgctgatac attacaaggt gcaaaaacag ttgtttggaa cggacctatg ggtgtatttg
    51121 aaatgagtaa ctttgctaaa ggtacaatcg gtgtttgtga agcaatcgct aacttagaag
    51181 gcgcaacaac aatcatcggt ggcggagact cagctgcagc agcagaacaa ttaggatttg
    51241 ctgacaaatt cacacacatc tcaacaggtg gtggcgcaag cttggaattg cttgaaggta
    51301 aagaattacc aggactagca gcaatcaacg ataaataaac gaccaagttt gctcaattct
    51361 gacgagtaat cgatcaaaag gtgaagggag ttttcatgac tccctagcca tttttcaata
    51421 aattaaggag tgtgttcctc aatgcgtaaa cctattatcg caggtaactg gaaaatgaac
    51481 aaaactgcat cagaagcaaa agaatttgct gaagcagtaa aaaacaaaat cccttcaaat
    51541 gacaaagttg attcagtcat cggatctcct gcattattct tacaagaatt aatgacatca
    51601 gctgaaggta cagaactaaa aatctcagca caaaactgct actgggaaaa ctcaggtgcg
    51661 ttcactggtg aaacttcacc agcagctctt gctgatctag gtgttcatta tgtgatcatc
    51721 ggacattcag aacgtcgtga atatttccat gaaacagacg aagacatcaa taaaaaagca
    51781 aaagctatct ttgcaaatgg tatgacacca atcctatgct gcggcgaatc tttagaaacc
    51841 tatgaagcag gcaaaactgc tgaatggatc gaaggacaaa ttacagctgg tttagctgat
    51901 ctttcagctg aacaagtgtc aaacatggtt attgcttatg aaccaatctg ggcaatcggt
    51961 actggtaaat cagctgacgc acaaatcgct gacgaaattt gtggagttgt acgtcaaaca
    52021 gttgaaaaac tttatggaaa agaagtatca gaagcagttc gtatccaata cggcggttct
    52081 gtaaaaccag aaaatattgc tgaatacatg gcaaaagaaa atgttgacgg tgctttagtc
    52141 ggtggcgcaa gcttgcaagc agattcattt ttgtcattgt tagacgctgt aaaataattg
    52201 ttgaaaattt gcgaaaaatg caagaaatgt ttgcactaat gagcaaaatt aactaaaatc
    52261 gtatatgagg gaaatccctt aggaaaaaac aaactcaaag gagagacaaa acatgtcaat
    52321 tattactgat gtttacgctc gcgagatctt agactcacgt ggtaacccaa caatcgaagt
    52381 agaagtatac acagaaagcg gagcttttgg ccgcggaatg gttccttcag gtgcttcaac
    52441 tggtgaatac gaagcagttg aattacgtga cggagacaaa gctcgttatg gcggtaaagg
    52501 tgtaactaaa gctgtcgaca acgtaaacaa catcattgct gaagcaatca ttggctacga
    52561 tgttcgtgac caaatggcta tcgacaaagc tatgatcgct ttagacggaa ctcctaacaa
    52621 aggtaaatta ggtgcgaacg ctattttagg tgtttctatc gctgttgcac gtgcagctgc
    52681 tgactaccta gaagtacctt tataccacta cctaggcgga ttcaacacaa aagtattgcc
    52741 aacaccaatg atgaacatca tcaacggcgg atcacatgct gataactcaa tcgacttcca
    52801 agaattcatg atcatgcctg ttggcgctcc aacattcaaa gaagctctac gtatgggtgc
    52861 tgaagtattc cacgcattag cttcaatctt gaaagctcgc ggattagcaa cttctgttgg
    52921 tgacgaaggt ggatttgctc caaaccttgg ttcaaacgaa gaaggttttg aagtaatcat
    52981 cgaagcaatc gaaaaagctg gctatgtacc tggtaaagac gttgttcttg ctatggatgc
    53041 tgcttcttca gaattctacg acaaagaaaa aggtgtttac gtactagctg actcaggcga
    53101 aggcgaaaaa acaactgacg aaatgatcaa attctacgaa gaattagttt ctaaatatcc
    53161 aatcatctca atcgaagatg gattagacga aaacgactgg gacggattca agaaattaac
    53221 tgacgtatta ggcgacaaag ttcaattagt tggtgacgac ttgttcgtaa caaacactca
    53281 aaaattatct gaaggtatcg aaaaaggaat tgctaactca atccttatca aagtgaacca
    53341 aatcggtaca ttaacagaaa ctttcgaagc tatcgaaatg gctaaagaag ctggctacac
    53401 agcagttgta tctcaccgtt ctggtgaaac agaagattca acaatctctg atatcgctgt
    53461 tgcaacaaat gctggccaaa tcaaaactgg ttctctatca cgtactgacc gtattgctaa
    53521 atacaaccaa ttactacgta tcgaagacca acttggtgaa gttgcagaat acaaaggttt
    53581 gaaatctttc tacaacttaa aaaacaaata attcttttct aatgaagata catgatcgac
    53641 tattgaaaga tagtcgagta tgatcactta gttaagtaat cgaactctct acttgctgaa
    53701 atatcagcag gtagagagt
//
LOCUS       DADLIO010000012        49849 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.012, whole genome shotgun sequence.
ACCESSION   DADLIO010000012 DADLIO010000000
VERSION     DADLIO010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 49849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49849
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.012"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(105..629)
                     /locus_tag="JOX41_000838"
     CDS             complement(105..629)
                     /locus_tag="JOX41_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAY6448602.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="JOX41_000839"
     CDS             complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="JOX41_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HAY6448603.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(1218..2198)
                     /gene="pta"
                     /locus_tag="JOX41_000840"
     CDS             complement(1218..2198)
                     /gene="pta"
                     /locus_tag="JOX41_000840"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HAY6448604.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(2351..3031)
                     /locus_tag="JOX41_000841"
     CDS             complement(2351..3031)
                     /locus_tag="JOX41_000841"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HAY6448605.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            3157..4026
                     /locus_tag="JOX41_000842"
     CDS             3157..4026
                     /locus_tag="JOX41_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAY6448606.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            4052..4567
                     /locus_tag="JOX41_000843"
     CDS             4052..4567
                     /locus_tag="JOX41_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448607.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(4614..5177)
                     /locus_tag="JOX41_000844"
     CDS             complement(4614..5177)
                     /locus_tag="JOX41_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAY6448608.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(5232..5411)
                     /locus_tag="JOX41_000845"
     CDS             complement(5232..5411)
                     /locus_tag="JOX41_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448609.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(5488..5997)
                     /locus_tag="JOX41_000846"
     CDS             complement(5488..5997)
                     /locus_tag="JOX41_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448610.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(6093..6473)
                     /locus_tag="JOX41_000847"
     CDS             complement(6093..6473)
                     /locus_tag="JOX41_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAY6448611.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            6803..7552
                     /locus_tag="JOX41_000848"
     CDS             6803..7552
                     /locus_tag="JOX41_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HAY6448612.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(7873..9090)
                     /locus_tag="JOX41_000849"
     CDS             complement(7873..9090)
                     /locus_tag="JOX41_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAY6448613.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEESTLRSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFSNRLTPYALTLIRLFPHPDFVLASTRTKIKNKLINETRKKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQKKALATQMIKKAEGSPCFLLYQTFP
                     GIGALTAALLLGELGDITRFKTHKQLNAFVGIDIRRYHSGKYTGQDRINKRGNPKARK
                     IIFFTIRNMIRQQRAAPNHIVDYYYKLKKQPIPKKDKVATVACMNKLLKCMHAMVRAH
                     TEYDYAYAVSVDH"
     gene            complement(9348..10625)
                     /locus_tag="JOX41_000850"
     CDS             complement(9348..10625)
                     /locus_tag="JOX41_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448614.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(10704..11348)
                     /gene="pcp"
                     /locus_tag="JOX41_000851"
     CDS             complement(10704..11348)
                     /gene="pcp"
                     /locus_tag="JOX41_000851"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HAY6448615.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(11547..12491)
                     /locus_tag="JOX41_000852"
     CDS             complement(11547..12491)
                     /locus_tag="JOX41_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HAY6448616.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(12493..13179)
                     /locus_tag="JOX41_000853"
     CDS             complement(12493..13179)
                     /locus_tag="JOX41_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HAY6448617.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            13653..13973
                     /locus_tag="JOX41_000854"
     CDS             13653..13973
                     /locus_tag="JOX41_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HAY6448618.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            14127..15032
                     /locus_tag="JOX41_000855"
     CDS             14127..15032
                     /locus_tag="JOX41_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAY6448619.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            15029..15802
                     /locus_tag="JOX41_000856"
     CDS             15029..15802
                     /locus_tag="JOX41_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAY6448620.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(15983..17407)
                     /locus_tag="JOX41_000857"
     CDS             complement(15983..17407)
                     /locus_tag="JOX41_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAY6448621.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            17618..18064
                     /gene="nrdI"
                     /locus_tag="JOX41_000858"
     CDS             17618..18064
                     /gene="nrdI"
                     /locus_tag="JOX41_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HAY6448622.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(18129..20111)
                     /locus_tag="JOX41_000859"
     CDS             complement(18129..20111)
                     /locus_tag="JOX41_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAY6448623.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(20125..21021)
                     /gene="murQ"
                     /locus_tag="JOX41_000860"
     CDS             complement(20125..21021)
                     /gene="murQ"
                     /locus_tag="JOX41_000860"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HAY6448624.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(21024..22085)
                     /locus_tag="JOX41_000861"
     CDS             complement(21024..22085)
                     /locus_tag="JOX41_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAY6448625.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(22296..22823)
                     /locus_tag="JOX41_000862"
     CDS             complement(22296..22823)
                     /locus_tag="JOX41_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAY6448626.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            complement(22890..24392)
                     /locus_tag="JOX41_000863"
     CDS             complement(22890..24392)
                     /locus_tag="JOX41_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HAY6448627.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(24650..25771)
                     /locus_tag="JOX41_000864"
     CDS             complement(24650..25771)
                     /locus_tag="JOX41_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAY6448628.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            25897..26838
                     /locus_tag="JOX41_000865"
     CDS             25897..26838
                     /locus_tag="JOX41_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAY6448629.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(26988..27884)
                     /locus_tag="JOX41_000866"
     CDS             complement(26988..27884)
                     /locus_tag="JOX41_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HAY6448630.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            28153..29493
                     /locus_tag="JOX41_000867"
     CDS             28153..29493
                     /locus_tag="JOX41_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAY6448631.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            29711..30154
                     /locus_tag="JOX41_000868"
     CDS             29711..30154
                     /locus_tag="JOX41_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HAY6448632.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(30658..32076)
                     /gene="nhaC"
                     /locus_tag="JOX41_000869"
     CDS             complement(30658..32076)
                     /gene="nhaC"
                     /locus_tag="JOX41_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HAY6448633.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(32479..33702)
                     /locus_tag="JOX41_000870"
     CDS             complement(32479..33702)
                     /locus_tag="JOX41_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HAY6448634.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(33733..34572)
                     /locus_tag="JOX41_000871"
     CDS             complement(33733..34572)
                     /locus_tag="JOX41_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HAY6448635.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(34589..35269)
                     /locus_tag="JOX41_000872"
     CDS             complement(34589..35269)
                     /locus_tag="JOX41_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAY6448636.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(35271..36344)
                     /locus_tag="JOX41_000873"
     CDS             complement(35271..36344)
                     /locus_tag="JOX41_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAY6448637.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     gene            complement(36991..37662)
                     /locus_tag="JOX41_000874"
     CDS             complement(36991..37662)
                     /locus_tag="JOX41_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAY6448638.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(37749..40427)
                     /gene="mgtA"
                     /locus_tag="JOX41_000875"
     CDS             complement(37749..40427)
                     /gene="mgtA"
                     /locus_tag="JOX41_000875"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HAY6448639.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            41086..41523
                     /gene="ndk"
                     /locus_tag="JOX41_000876"
     CDS             41086..41523
                     /gene="ndk"
                     /locus_tag="JOX41_000876"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HAY6448640.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(41545..42411)
                     /locus_tag="JOX41_000877"
     CDS             complement(41545..42411)
                     /locus_tag="JOX41_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAY6448641.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(42571..44664)
                     /locus_tag="JOX41_000878"
     CDS             complement(42571..44664)
                     /locus_tag="JOX41_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAY6448642.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(45413..46036)
                     /locus_tag="JOX41_000879"
     CDS             complement(45413..46036)
                     /locus_tag="JOX41_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448643.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(46195..47592)
                     /locus_tag="JOX41_000880"
     CDS             complement(46195..47592)
                     /locus_tag="JOX41_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAY6448644.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(47624..48595)
                     /locus_tag="JOX41_000881"
     CDS             complement(47624..48595)
                     /locus_tag="JOX41_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAY6448645.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            48969..49394
                     /locus_tag="JOX41_000882"
     CDS             48969..49394
                     /locus_tag="JOX41_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448646.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
BASE COUNT        14359 a        10386 c         8798 g        16306 t
ORIGIN      
        1 tattcaaaaa aaatggactg cgacacgact tttgtcacag tcccttcgtg tgtttttctg
       61 ccttctcaaa aggatgacag tttctcactc ttttcctatt tcttctattc aatcaaataa
      121 ctcattttat atacatctaa aaattcacct agatctgttc ttgcccctct aggcatgacc
      181 gcttcgattt ggaagcccat ttttcggtaa aggtgtacgg ctctttcatt acgaacttga
      241 acgtcaagct ccaatcgaaa aagtacaccc atttccttcg cccaactgat gatttcttct
      301 agcataagag tgcctagtcc cattccccaa tattcctgca gaatactgat accgacttct
      361 cccacgtgag acaaacgaaa ttgactgtct gccttgacag atgctgttcc aataatcgtc
      421 ccttcataga ttgcaagcag caataaatta ttattgcttt cgtatatata atccaactct
      481 tcttctaagg tttctggtgg taacaggagt tctgcttcat ccaaaactaa aaattctgtc
      541 tccttattaa cttgtcccat catcaaaaga atgtcttttg catctcctgg cactgcttcc
      601 cgcaagatga tcccaacttc ttcactcatg attttcagcc catttttcta gaattcgctg
      661 tttgaaggtt tcactttgct ccccgtatga gattagtttc acataccgct tttctaaatc
      721 tgtatcactt ttttctaaaa tcagttccaa ataatcctcc ggcagtgctt cttctaatag
      781 atttccccat tcaacaacgg aaagcccatc accttcaaaa tattcatcta accctaaatc
      841 tgctccgcta gctgctaccc gataaatatc catatgatac aacggaatcc gaccttgact
      901 atattctcta ataatcgtgt atgtcggact tttgatcatt tgcgttatcc ctaatccttg
      961 ggcaattcct ttcgtcaacg ttgttttacc cgcacctaga tcaccagtca atatcagatt
     1021 gtcacctggc attgcggaat gaccaattgc ctctgcgaat tgttctgtca ttgttaatcc
     1081 tgatagttcg atcatttttc atcttctccc gctcttcttt ctttttgcca gtatatcgcg
     1141 taatgaagtt tttttaaaga aaaaatgaac tagtcaagaa cagcagctgc tgtttttggc
     1201 tagttcgcgt gtatttgtta atcaatcaat gtttgtgctg ctgtgataat cgataattta
     1261 tatacatctt cttcatttgc tccacgagac aaatcagaaa ccggtttgtt caagccttgt
     1321 agaattggtc cgattgcttc aaagttaccg aaacgctgag caattttata gccgatattt
     1381 cctgactgca attctggaaa tacaaagact gttgcttgac cagctacttc tgaatctggc
     1441 gctttcagtt gtgcaactga aggaacataa gaagcatcaa attgcaattc gccgtcgatc
     1501 atgtattgtg gcgctagttt tttagcgatt ttagttgctt caactacttt gtctacttct
     1561 ggcgatttcg ctgagccttt tgtcgagaag ctcatcattg ctacttttgg ttcgatatcg
     1621 aacaattctg ctgtttttgc agaatctacg gcgatttcag ccaattcttg cgcagttgga
     1681 ttcacgttga tcgcacaatc cgaaaagaca tatttttctt gatctcttcc acgtaccatg
     1741 atcatcgctc cgcttgtccg actgatgcca ggctttgttt tgatgatctg aagtgctggg
     1801 cgaacagtgt cgccagtcga atggatcgct ccagagacca ttccgtctgc aatccccata
     1861 tacgtaagca tcgtaccaaa gtaattcaca tcttttaaaa tcttttctgc ttgttctttg
     1921 gatgcctttc catttctacg ttcaacaaaa gtatccacca tttcatccca cttatcgtaa
     1981 ttatcagggc tgatgatcgt aaagctagat gttttgattc ctctggcatg cgctgcattt
     2041 cttatttctt cttcgttccc tactaaaatg ggttccacaa gttcttctgc tttcaaccgg
     2101 gcagctgcgc ctaaaatacg agcatcagta gcttccggga aaacgatttt gatcccacgg
     2161 cgaacaattt taaatcttaa actatcaaac aattccacaa gatgacctcc agacgttttt
     2221 atatgtatta tcatacacta ttccagaaaa aaagaacagt ttattttatc tgtatcagtc
     2281 aaaaatgctg gaaaaattaa gtttttcaca tacaaagcga actgcactat aacaggaaag
     2341 cgctgtttta ttacactgtt tcaggcagtt gccaatcaat cggttcttct cctaacgcaa
     2401 ggagcgcatc attcgttttc gagaagggtt tggaaccaaa aaagccacga cttgcagata
     2461 acggactggg atgtggagat gttatgatga tatggcgact cttatcgatc attttgattt
     2521 tttcttgtgc cggttttccc cacaagataa acacgattgg tttttcccgt tcatttaatt
     2581 tttcaatgat cgtgtctgtt aatctttccc aacctttccc gcgatgagaa tacgcttgcc
     2641 cttcccgaac ggtaagaacg gtgttgagta aaaggactcc ctgtttagcc catgacacta
     2701 gatttccatg ttgaacaggt gcgattccaa gatcatcata aagctcttta tagatatttc
     2761 ttaacgatgg cgggatcttt acgccaggtt gcacagaaaa agataagcca tgagcttgat
     2821 tttctccatg ataaggatct tgtcctaaaa tcaccacttt aacttcttca taaggagtca
     2881 attccaatgc ttcatagata tgatacatat ctggatggat cttttgggac gcatattctt
     2941 tttttaaaaa ttctcttaga tgcagataat aatcttttga aaattctgag gacaaaactt
     3001 cttgccaact gttatgaatg atttctttca aaaactccac ctcctaataa aaagaataac
     3061 tcacattttc ttcaatcaca agggacaatc ttcaccctca gcacttgatt aatatggtaa
     3121 actaggaaca agaagcagaa aggaacgata atcattatga tcaaattaat tgcatcagat
     3181 atggacggca cattattaga tgcccatatg agtgtttctc ctgaaaatgc cgaggcgata
     3241 cgttttgcaa atgatgccgg tgttgagttc atggtcgcta ctggtcgaaa ctatcaagaa
     3301 gctcgcgcag ctttagatga ggtaggaatc gattgtgcga tgatcacttt gaacggggca
     3361 caggtatttg ataaagaagg aaattcattg tttaccgtgt cgattccaaa taatcaagca
     3421 atctctgttt tagatattct agatgctaac ggtatttact atgaagtagc aaccaacgat
     3481 ggtctttatt ctgaaaatca agcgaaacga attgaaagtt ttgcttccat ggtggctacc
     3541 catttacctc accttacgta taaaatggcg attgccatgg cctcagctaa gctggagtta
     3601 ttgcacatca catacgtgga cagtattcgt gctattttgg aagaaaagaa tctggaagtt
     3661 ttaaaaatta tttgttttca tacagaaggg ccagctgtat taggtccagt tggaaagcag
     3721 atttctcttt taggcgatct agccgttact tcctctggtc aaaacaatat cgaagtgaac
     3781 cataaaaacg ctcaaaaagg aattgctgtt gcccatgtcg ctcacgagcg tgggatttct
     3841 ttagaagaag tcatgacgat tggcgataac ttcaatgatg tcagcatgct gcaagtagca
     3901 ggagtcagtt tcgcaatggg aaatgcagaa atcgaagtaa aagattatgc caaatataca
     3961 acggacacaa accttgaatc tggcgtagga aaagccatat tgcgcgcgat tgcagaagac
     4021 ttgtagtttt atctagaaaa gagggatata gatgtcagaa tttttcattc aggaaaagca
     4081 gcttggacgt gcaactcgga caattgtcaa aaacgaaaaa ggacattccc tgtttttgat
     4141 ggttggtcgc tggggaacaa agggcgatgc attgtctctt tatgccatga atggcgatct
     4201 cgttgctcac atcaagcaga taagcctgac attcggtacg cgttttgagc tgtataaaga
     4261 gttcgaaaag gtgggaacca tgcagaaaat attcaattgg cccggtgact tttattatat
     4321 tcgtagactt cactggacag tccaaggtga tatctataat catcaatatc aaatccatca
     4381 tttcaatcag caaatcatga aaatggataa agcaacactt ttttcaggag attactatgt
     4441 attggatgtc tcaaatgatg aagatgctcc agtttgtatt tgtattgctg cggttttaga
     4501 ttactggctc taccgtaaag acaaaagtcg cgataagcct gtttcttacc gacttaactt
     4561 aagttaaaaa gatgtacctg aaatgcggaa atacgcattt caggtacatc tttttagata
     4621 ttcttttgca tatgatcata aagatgacca ctgatcatcc gctgaccgac aactttgaag
     4681 tcatggcgtt cgtataattt tttagccttt ggattttttt catccacact tagaccgatg
     4741 acggagcgat tagctttctt cgccaattta ggtaatgctt ctaataatcg cgaaccgatg
     4801 ccttgtcctc taaaatcttc tgatacactg atagagtcca aataccattc gttgggaaac
     4861 gtttctttat caatgaacaa acgtgtagac gcatctagct gatatttctc taagataggt
     4921 accagtggct gatcgatgat tgattcttct tcatctgtat aaccgtaagc aactcctgca
     4981 actttaccgt ctatttcttc tacgatacct cgtgaataac tgtaacgata atttggatca
     5041 gtgattgctt cttctaaaat ctctaaagtc ttttgttccc ctgtctgctt caaaaatggc
     5101 agttccatat cttttagaat cactaagatc aatggggcga tttctggagc atcttctttt
     5161 ctcgcaaaac gaatcatagt ttcctctcct tttctccatt ctaacatgca gaaaaagaaa
     5221 tcgcaaaatc gttattttaa aaaatcttca atcttttcag taatgaaata accatgagta
     5281 acgattcttg ccgcttcagt tcggcaataa gggcagacga ctggcatttc tttatcatta
     5341 tgttcgacta cattattgac ttcttcgtat gcaaattttt ttccgcaatt agggcatttc
     5401 attttttcca tgttatctca acttcctttc atctttactc tcttagctta ctcttatatt
     5461 gtaaaaaaga gaagcaatat ccttcttcta tgcagatatc catacctgac ggtcctgttc
     5521 tccatctatt aatcggactt tataataagg acgttcatct ttgactagaa gtgtccactc
     5581 tttcactttt gcttttttcc cgtagtagct gactgcttcc ttcatcgctg cttgcggttg
     5641 tttgaactct tccgtttttt ctatatcaaa aagatgttct gcggcctttt ccgtgtcatt
     5701 tcgtacggtt gttttcccag tggatggatt gactgctatg acttgtcctt cacaaaaaaa
     5761 ctggtattca tatgttgcat tcgtaggatt ctccaaatct ttttcaactg caaaatgaat
     5821 agcagatatg ttatgttctt ttgtttcgtt ttttacgatt gctgctgctt ttttcaatga
     5881 gatccgatat tcctggtcac taatatcatc catgtgaaaa gcggcattga gcagtcccgt
     5941 cataccggta atccctatta cgatgagggc agcaacacca aacatcattt ttttcattct
     6001 tcattctcct gtttcttttt tttaaagaat atcaagaaat gaacgaatga aaaatcgaat
     6061 gaaacgaaaa aaaagtgaca attttgttat ctttattcgt gcagttctaa tggcaatccg
     6121 tctggatcaa agaaaaacgt catttttttt cctgtaaagg tatcttctct aatcggttct
     6181 gattcgatcc ctaaggactg caattctgca attgtttctt caatatcgtc tactttgaaa
     6241 gcaagatgac gcaagccaca agcttctgga tagtttggtc gttgtggcgc attagcaatt
     6301 ccaaaaatct ccaattcagc acttcctagt ttcagatcta atttatagtc atctcgttct
     6361 ttgcggtaat tttctctgat tacttcaaat cctaatttat taacataaaa atcacgtgat
     6421 ttctgataat ctgaaacaat gatggctata tgatggatcg ttgtaaggtt catatgagca
     6481 ctcctattct tcgtttaagc tcggatctat attaatctcc agttccattg taaatgtgtc
     6541 agattgaaaa aaatagctgt ttttcctttt tataagaaaa aaggcaaaaa aaacagaaag
     6601 taggtcctcc aagacactct tcctgttccc aatataataa atgaaagtaa gaaattatat
     6661 tttcaagaaa acaaacagaa aattatcata acacaaatta tttataattg aaagactagt
     6721 tttttttcaa gaaaagcata caatagattg tgttagtaaa tacagaacac actacattta
     6781 gtgtcttaag gagtcctcat acatgaagtc atattttcag tttttagctc atcagctaaa
     6841 aggctggccg caacaaaatt attatctttt ctttttcagt cttggctgcc aggtcatgac
     6901 tcttgtcaat agtcccatca cttggctgtc cgttattaca tttatcggta ccacgcttgg
     6961 tgtattgtgt attttatcca tcaatgcggc aaaatcagtc aacggtattt taggtatttt
     7021 gtctgcgatt tgttttatta tcgttgggtt ttcagcaaag aactatttaa gtatcggtga
     7081 acagattgct tatatgatca cattggatat ccccgtattg ttaagtaaag aatggaatca
     7141 taatatggct tcaaaaatcc gaaaattcac tggaaaaagc tggtttatcg caatcatcag
     7201 tactttcctt gtctatcttg tttcaggatt cctgattggt cgttatacag atgatcctcg
     7261 gccgtgggta gatgccattg ctttttctat tagcttgact gctggtatca tcagtttctt
     7321 gcgttacaac aaccaatatt actggtggtt agcttcaggg cttgctcaaa tggtcctttg
     7381 gtatatttca tttacgcatg gatctgcaag tttggcgatg ttcgtgaaca gctctgttta
     7441 cttgctgaat gatgtccttg catttaccgt ttcaccttgg tataaccaaa aagaacgtga
     7501 acgtatgcaa aaaatggaag aagaatacta caacgcacaa caacacgcat aaaaaaactg
     7561 agcgtgggac aaaagtaaag aacacttttg tctcacgctc taaacacgta taaacggcgg
     7621 aatcagaagc aactccttcg gaaataagct gaaattcaca aaaatttgaa aagcaatttt
     7681 cgtgaatttc ttcttatttc ttggagttaa acgcttctgt cccagcctct atttcctacg
     7741 attagtcaag taaaaggtgc aagaaaaata gctcgtaaac gaaagcgaca aaatcaaagc
     7801 acaccaaata aagccccgtt cgtaaaaaat tttcgatctg ggcaaagaag tggtatactg
     7861 taagtggttt agttaatggt ccactgagac cgcgtacgca tagtcgtact ctgtatgtgc
     7921 cctaaccata gcgtgcatac atttcagaag cttgttcata caagcaactg tggcaacctt
     7981 atctttctta gggataggtt gcttttttaa tttgtagtaa taatcgacaa tatgattagg
     8041 agctgcgcgt tgctggcgaa tcatatttcg aatggtgaag aaaataattt tccgtgcttt
     8101 gggattacca cgcttattga tgcggtcttg gccagtatac ttacctgaat gataccgtcg
     8161 gatgtcgatt ccgacaaagg cattcaattg tttatgggtt ttaaatcgtg tgatatctcc
     8221 taattcaccg agcaataaag cggctgtgag tgcgccaatc ccagggaacg tttggtacaa
     8281 caaaaagcaa ggagagcctt cggctttttt gatcatttgt gtcgccagtg cttttttttg
     8341 ttcgagtaaa tcttggagaa gttcggcgta atagatcgtt ttttgacagt ggatactgtc
     8401 tttttcaaca gctggatagg cacactgtgc atagtggatg atttgatctg ccttttgctc
     8461 ggcacgattc gcggagattt ttttccgtgt ttcgttgatc agtttatttt ttatttttgt
     8521 ccgagtagat gccaatacaa aatctggatg gggaaaaaga cggatcaatg tcaatgcgta
     8581 aggggtcagc ctgtttgaaa agaactgttc aagctctgga aaagtcaatt gaaggcagtt
     8641 gtgtaaatcc atgcgcagac gagtgatttt cttctcaatt tcttgataaa aacgggctaa
     8701 atcgcgcatc tctaagtaaa aattgctttg tacttctttt ggctgacgtt gatttttaag
     8761 atgagtctgt gcgagccggt gggcatccga tttatctgtt ttccaactgc gtaaggtgct
     8821 ttcttccatc tgttttttcg cctctaacgg gtttaacaaa cagtaagaaa agtgatgatc
     8881 ttgaaagaac ttttcgactg gtctggaata aatccccgtt gcttcaaaaa caatcaatgg
     8941 acgctcaggc aagtgctgga tctcttcgag taatgcatga aatcctcttt gagtgtgttc
     9001 aatctcgtct tcaaataagc aggtgtcgtc tttgtatagg acactgtagc tgtgtcccat
     9061 tgaaacatct aatgcaagaa tgtaaggcat ttgttttcct cctttttaag ttttgaaaga
     9121 actttactgc ttcatttcga ttccaatttc ctatacacgg gctcatggcc ccaacatacg
     9181 taaacctgat tctaaaatga cagtaaagaa gttcggtttt tgatagggac tcgtagtcct
     9241 caaggctttg ttcgaacttt ctttcactct tcactataat ctaaaaatag aaaatagagg
     9301 agaacatcat tcgtcaatga tgttcccctc taatcttagt atgtttttta tagtaattcc
     9361 ttcagatact ttcttgcctc atcattgaaa cgcagtgatt cttctaactt ctgataatat
     9421 tccaacgctt gtttctgagc ttcagtaaaa cgataatgtt ttcctttcca tttgtcgatt
     9481 gtctcttgca catttccaga ttggatatct ttcactacta gttgccattt ttcttttgag
     9541 actgtacggt ctttcttatc agcagattgt atagcttctc gttctttacg caatactttt
     9601 aaaaaaccat ttctgactat ccgaggaatg ctgtcgaaga acccttctgt aaaaccatag
     9661 cgacaatatt gcttccaaat aaatagatag atttttggtt ggatgaatcg ttggtttttc
     9721 gcaaaatatt ccatctgagc agtgacttct ggtgttcgtt gacgttttgt ctttctcaac
     9781 acggaaataa atgtttcaaa ataagcatta ggatgtactg gcacttcttc atatacgatg
     9841 gattgccaat ctttacgtaa aaatgcgcga tagttgatca agaattcttc tacatccttt
     9901 actaattctt ctgcaaagtc gtcaaatagt tcttttttta tctgtcgctt ttttgactgc
     9961 ccattgatgt gttcacttat tttcttgatt tcattttcca atgcttgata atccgctatg
    10021 taaatcggca tttctacttg gcgaaattct gcgagccgct gagctaattt tatatccggt
    10081 aaatatggct gtttcatccg acgattttgg tacaagacaa aacagtattt ttgccatagt
    10141 ccttcaggaa aatcgatatt cttctgctta agccataata attcgtctaa ggccagatca
    10201 acttttgtca ttccctgatg gatcgaagct gccactgtcg gagagacatg caggtgatcg
    10261 gcaaagtggt tgatgcctag ttttaggatc tttccggttt ttggcgattt aacgatgtat
    10321 tgcactttta attctctacc acactcacaa tacaattttt gctggcttcg ttttgttcga
    10381 aaaaacggat tgatcttgaa gtcagaaaac acccaatctg ttgcagctaa ataatgttct
    10441 tccataaaac gagagctgat tagatatcgg cggtgcttat cgactagttc ccgctgtttt
    10501 ttcgttaatt ttgcatagat ctcccaacgt tgactgcttg tgtattgttt agaaattttg
    10561 atgggatagc ttttgctgat ttcttttgga aaccattctt caaagacgga ttgccattct
    10621 tccacggctg tttctttcct ttctaattac aaaaagctgg ctactaacat aacgttagca
    10681 accagccagt gtttcttgct aaattagtga gttgttccgg catttccgga aatatcttct
    10741 ttattttcta ctgctgcttc aactgcataa gtcaaagaag aagcaatgtc ttctaaagac
    10801 atagaaggcg tacccactgg acgatcgatc acttgatcgg gtgagaatgg cacgtggatg
    10861 aacccacctc gaattgccgg gaattgtgtt tcgatcaaat gaagcaaacg atacatgata
    10921 tcattgcaga caaatgttcc tgctgtataa gagatgtacg ctggtagacc atgatcttgt
    10981 acattttttg tcattgcttt gattggcaat gaggtaaagt aagcggctgg accgttttct
    11041 tctaaagccg tatcgaatgg ctgatttcct tcattatcag ggattcttgc ttctgctaga
    11101 ttgattgcga cacgttcgaa cgagactgct gaccgcccac ctgcttgtcc gacacagatc
    11161 acgacatctg gttggtgctg ttggatggct tctttgacta cttgactgct tttttcgaat
    11221 acggtcggta cttccacttt gatgatttca gcaccgctga tttcatctgg catttttttt
    11281 actgcttcat aggctggatt cactttgtcc ccaccaaatg gatcaaaacc tgttactagt
    11341 actttcatct gttgttcctc cgtccgattg atttaacata tggttatctt ttatcatacc
    11401 attttccttg aacagcgtaa ataaaggaaa caatagttta aataacataa cagatcaaac
    11461 ttaatatatt cttataaaaa aatagtgttc cactacaatg ttagaagagg ttgcgacaat
    11521 tattctgtca caacccctct cttctattat ttaaatagaa tcatataagc aatttggaaa
    11581 actagcataa ataacgcaat aaacaactgg tttttgatca ctccgtattt gtctttcatc
    11641 tccagcatcg ctacaggcac gatattgaag ttagcagcca tcggtgtcag cagggtccca
    11701 caaaaaccgc aagtcaatgc aaccattcct attaacgctg gattcgctcc atgactaaat
    11761 acgaatggtg caccgatccc aaccgtcatc acggtgatgg ccgcaaatgc attccccatg
    11821 attaccgtaa atatcaccat gccaagagcg taaatgatga tgccgatgtt cacatttcct
    11881 tctggaacga tcgtacctac tgcattggaa atcactgtcc caactccagc gcttgtaaat
    11941 accgcaccta gagaagctaa aagcattggc aacatgctta acggccctac tgtgcccagc
    12001 atatctgctg catcatctaa aaatgtactt ggtcgattat ctcgagaaaa gaacatcaag
    12061 attagcatgg ctgcaaaaac accgacgccc acgccgacta aagcacctaa attggtaaat
    12121 agagcaaaca agatcgcaaa gacaccgata ctcaaagctg gaataaaaat tttcattcct
    12181 agtttgtctg acattttttc catatattct tttgatggaa gccggctttc tcctttgctg
    12241 actttcttag caattgctgg tatggtcatc gcaaagatca agccaccgtt cacgattgcc
    12301 ggaagccatc ttcctcctgc aataactacc cctaagaccg tccagaaaaa ggctgaccca
    12361 taacgatgag gattggtttt atctgttaaa tttcttactc cagtgtaaat caatacgagt
    12421 cccatcacga tataaaggat ctccagtaat ttatcgccta ataaaatatc aggatttgta
    12481 aaaaagtcca tcttattgcc cctttcctgg ataatatttc ttcgctaatt tcttttcttt
    12541 aagatagaag tagacacttg ccacaactaa agccgtgata gccactggaa cttccactaa
    12601 agcaagctgt cccaatgtta cgtcatatcc tagatctttc agtgttgatt ggactagcaa
    12661 cgcccctgct cctccgatga atagtacttg gccaaagaac cagcagacat tttccatagc
    12721 tgaagccata ccttttagtt cttcttcatg cttaggatgg acttctaacc cttttgattc
    12781 gatggtcccc aatgccatcg gtaaaatgat tggacgaaca aatccagcaa ctccaccaaa
    12841 actcacgtta aaagccgcaa agatcattcg aaagatccca taaatatcta caatcatacc
    12901 agcagatact ttcttgaatc gcttgatcaa ggaagccgct gattctttca gaccatttct
    12961 ttcaagcgtt cctgttgcca acataatgat gataaaaatc gccatcccgc gattgtttac
    13021 aaaacttgta cctaaaagtt ctaacattcc ttgaatgcca agaccgccag tcaaagctgt
    13081 aacaactaaa gcaaccatta cgatcaatat cgagtctaat ttaaatgcaa acccgagaat
    13141 aacaatcaag acgcctaaaa ggctaagata attttccata tattttcctc cataaaatga
    13201 caatattttt ttaattataa agcaaaacac ataaaaaata tagttgtttt ctcacgaaat
    13261 agacactatt tttaaatatt tttcgttatt tttttatcac aaaaattatc ttacttattg
    13321 taaggtaaag ctttttttaa tttattgccc gataatatat agaaataagg tctagttact
    13381 gtttttttta aatgattaat aaataacaac ttctttctat gaaattgcaa agcattcatc
    13441 ttcttttccg ctaacgatat atccgtcagt gcttggtaca ctttactaaa aagtatgaga
    13501 ttgccgatat ctggataggt gtgctatact acagaaaaag atatacaatc tgccaccggg
    13561 taggataaag aggatgatca ttccattagg tctttgaagg gatgattttc ctctttttgt
    13621 gtattttttt atagttaagg aggaatgtaa gtatggcatg gatggaatta atcatagcag
    13681 gaattttgga agtattctgg tcaacgatga tgaaatggag tgatggtttt tctaaaatca
    13741 attattcttt ttacacagtg attggcatga ttgctagttt ttactttttg tcaaaggcaa
    13801 tcaaaagttt gccgatgagt ctctcttatc ctatctggac agggattggc gcagttggtt
    13861 cggtcataat tggtgtggtc ttgtttcatg ataagctgaa tctttccact tggttctttg
    13921 tggggatgct actcatcagt atcattggca tcaagattac tagcggccac tagacacttg
    13981 gaataagtac tgatcagaaa aaataagcct ttttatttaa tattcaattt ttttatgaaa
    14041 aaataagaaa taagtccaat gacctagcga cttctccact catcaggtgt atgcttgtac
    14101 tatctataga aaaggagtga atatttttga aaagtctttc ggtccaagaa ttatccaaga
    14161 actttggtca caaacaagcc ctcagcgatg tcagttttag cttatcccct ggcaaaatcg
    14221 ttggattagt aggtcctaat ggcgctggaa aaacaacgat catgaaagct attttaggac
    14281 tgatccatta ctcagatgga acaatctgta ttggtgaaaa tgagatttct ccctctagtc
    14341 ataaagggtt ggaacaagta ggagcattga tcgaataccc gggtatctat ccattcttaa
    14401 caggctatga tcatctgaag ttattctctg aaaccaacga tgtatctgct atcgacacta
    14461 tcgtgaatca gctcaagatg gaaaagtaca ttcacaaaaa agcgaaatcc tactcgttgg
    14521 gaatgaaaca aaaattggga attgctcttg ccttactgaa ccatccgtct atcgttattt
    14581 tagatgagcc gatgaacggt ttggatccac aagcaacaag agatgtgcga aaaatcatta
    14641 ccgacttggc tactcagggc acctctttct tgatctccag tcacttactc agcgagcttg
    14701 aaaaaatggt cgatgagctg atcctgatca atcaaggaaa gatcatcaaa caatgtacaa
    14761 tggctgaatt gaaccaaaca gcgcaagatt tcatcgttat ctctacaaca aatgatctag
    14821 ctgctcgaac gatcttgaca gaagctggat atactttgga agatcctgat aaaatcaagc
    14881 ttttaaaaga aaacgaagaa ttattaggaa ccgtgatcca gctattgtct gcacaaaata
    14941 tccatgtgac agacgtccag catctgacga atgatttgga atcttctcta ttggaaattc
    15001 tggattcagt aaagggggaa gaagaaaaat gacattgctt gtaaaacaag aattatttaa
    15061 attgatcaag aaaaagtcaa ctgctgtttt atctgttcta ttagttgttt tgctcatagg
    15121 aacagcactt ctagccaaaa aatacacgac gatcattgat ccagttgaaa tgactgctca
    15181 gctttttagt gccacatctt ggattgtctt tatcatgatt gcagctgcaa gcacgatcat
    15241 ttcgatggaa gcacaatatg gtacattgaa aaatctcctt tatcgaaagt attctcgagg
    15301 agaaatatta gtaagcaaat ggatcacatt agttatttat tctgtttatt tatacctttt
    15361 agctattatt gtcactgtgt tgatgaaact gattcttttc ccttcgattt ccttcacgga
    15421 gaaggtttct actggtcaaa cactgatcca aagcttgttc acttatactt tgggtagtta
    15481 tatcggttta tggctgattt taagtttagt gttgatgatt gcttgcttta tcaatagttc
    15541 cggcgcatcc atctcagcag gaatcgtctt ttattttgct tcgtcaatca tatctggtat
    15601 ccttattgca ctcatccaaa aatgggagtg gatcaaatgg aatccgatca gtatgttgaa
    15661 tctgcaaaac caaattggaa acgaagagat catgaagcaa ttgactcatc tttctactaa
    15721 tcaaatgcta ttcggtaatt tagcttacat cgttttgttc ttagcattag gatatctcgt
    15781 atttaagcga aaaaatgtat gatgactcat caaaaaagag gctgtgaaag agacgttcag
    15841 ccttattgcc gattggctgt ctcttaaaca ccgtttattc tgaaaaagga gctgtgacaa
    15901 catttgtgtc acagctcctt tcctagtatg tttttgaata aacgacaggc tcacaacctc
    15961 tctttatact tcttttatac ttctatacgt gaagcatccc agtggcaaat aaaaccattg
    16021 caatcactcc gaccatcgtc acacctataa gtaaaatctt atctaagtgg atatgttgta
    16081 caggctcgtt ttgctcctta cgtgctttga ggtaaaaata aatgcctggc aagaaaagaa
    16141 caagaacaag cattacttca ttaaaggcta cgactagcat agcccatact tgaaaggcac
    16201 ttgctaaaag ccctactaaa aattggaccc attctttccg ctgataagaa agtttcattt
    16261 ggtacaatcc taagaaaagc cacgtgaaga aaatagctgc tgtaccaagt gtgtaagcaa
    16321 agttataagc actgtcagtg aataataatg aaagtaaaaa gacattcgta cataacgtcg
    16381 tcaatacgat agcataagtt ggtgccccat ttttgttgag ttttccccat gctttaggca
    16441 aaagtccgtc ttcagccatg tttcccattg tttcaatcgg taagatcgtc catgagagcc
    16501 aaacaccaac taaagaaatg atcaaaccgc cgttgatcac gactgctccc catttaccaa
    16561 ccatcatttc aaacacatag cccatagcag gctgcgcctt gatcgtttgc agctgattca
    16621 tcgtcattgt cccatatgga agcatggaaa ccaagacgta aataataatc aagccgaata
    16681 tccctagaat cgttgctttc ccaacatctg attgtttttt tgctcgtgaa cctacgacag
    16741 aggctccttc aataccaaca aatacccaaa gcatcaccat gatgcaactc aatacttgac
    16801 tggaaaacgg gatcggctgt ccattcgcat tcaatataat gtcgctagaa aagttatcaa
    16861 tgaattgttg gatcgaaaac gtgctgatag ctactacaat aaataaaaat aatggcacta
    16921 atttacagaa tgtgacgata gcattgacga aactagcatt ttcgactccc cgattcacta
    16981 gccatgcata tccccataaa aagactgtac tcatcacgat cgatgccaga ttttgcccac
    17041 cttcaaatac tgggaagaaa tatcctaatg cgctcatcaa caatgttgca aaagctacgt
    17101 tgcctaacca gcatgtgagc cagtaacccc aaccgctgat aaaaccagcg aaacggccaa
    17161 aaccttcttc tgcgtaacta aagatcccgc cttttaaatc tggacgtttt ttattgatat
    17221 tattgatcga caaggagagc atcaacattg ctgttcctac gagtacccaa ctgaaaatag
    17281 ctgggccgcc agccgatccg gagatgtccg tcataatacc aaatacgcca cctccaatcg
    17341 ctgaaccaat tactaaggca gcaagtggaa ttaaaccaat tccttttttc tgttgctctg
    17401 tatccatgta agcatcctcc aaaataaaac cgcttttatc aaaaagtata acaaaccttt
    17461 tttattttta cttaattaat aaaaacttta atagaaatat aattctaccg gcttttttct
    17521 cattatacaa gcaaagcgcc tagtcccttt ccaaattaca ccaccaaaaa acttaaaaaa
    17581 gatgctatac taaaaggaaa gaattggagg atgatccatg aacattttat atatatcgat
    17641 ttcaggaaat acgcgtgcct ttgccaaaca tctagcagaa tatgctgaaa aaatgcatgc
    17701 agaagatcct gtcaatcctg aagttacttt aaaagaaatc catgaaaata gtgattttac
    17761 gaaagaaaca gaaccatttt ttactttcgt tcctacttat ttagacggcg gaaatggttt
    17821 agataacggt gatacagaaa tcttgaccga aacgatgcgt gaatatctgg aacatgaaga
    17881 caatcataaa ctttgtcttg gtgtagtcgg tagcggaaat aaaaacttca ataatcagta
    17941 ttgtctaaca gccaaacaat atgcacaaac atttggcttt cctttcttgg cagattatga
    18001 attacgggga acaccatctg atgtgacacg aatttatcag attttagcag aaaacaataa
    18061 ataataaaaa agaagaagct gaaaaataga tttcagtttc ttctttcgtt tctattgttt
    18121 ctatcatatt aagctttgac atccatcaca ggtgcttttg cttttgcttt acctgttttt
    18181 tccaagacaa agttttttac acgatccata ttggttacca agacgatcat ggatgtttct
    18241 ttgcctgctg ctttgatcgc ttctaagtca gcttctgcta caagcgtatc aggtgtcact
    18301 tgctgccctt ctgttacttt cacatcaaat ggcgtaccgc ctaagtcaac tgtgttgatt
    18361 cccatatgaa gcaagatttc taaaccattt ggcgttgtga tcccaatagc gtgtttcgtt
    18421 gggaagacag agctgactac cccagtaact ggagaataga tatgtccgtt ttctggttct
    18481 acaaagtagc cttcacccat catcttttgt gcaaaaactg gatcacttgc tttatctaaa
    18541 gaaacaactg ttccgtcagc aactgatgag aggatagtca cactttcagc tgaagtttga
    18601 ggtactactt tttcaggcac ttcatttact gtggctgttt cagtcgctaa ttcttctttt
    18661 tctaaacggt ctttaggaat accgaagaag aatgtagcaa cgaagccacc agcataagct
    18721 gccaataatc caaggatgta gcctaaccat ttaccgtcag agatcaatgg gatcaaagcg
    18781 gctcctgaag gtccaatagc gatagccccg acatttccga tcattccgat cactgccccg
    18841 ccgatacctc caccgataca agcagtaata aatgggcgtc ctagaggtaa tgttactccg
    18901 taaatcaatg gttcgccgat tcctaggatc ccgactggta aagctccttt gatcatttct
    18961 gttaattctt tatctttttt gcagcgaatc cataatgcca atgctgcacc cacttgtcct
    19021 gcaccagcca tcgcaagaat tggaagcaat agcgtacgac cagtttcatc aatcatttgc
    19081 acatggattg gagtcaaaat ttgatgcagt ccgaacataa ccatcggcaa gaataatgtg
    19141 cctagaacga agccggcaaa tgctccacca acgccaagta cccagttgat cccaccgacc
    19201 atgccatcag aaatgaaacc tgctaaaggc atgatgaaga aaatttcaat cagaccgatg
    19261 gcaatcaatg aaagagttgg tgtaacgatg atatctaccg catcaggtac tactttatgc
    19321 agttttttct caacgattga caatagccaa acagcgaaga tgacacctag gatcccacct
    19381 tgtccagctg caagagcttc accagtaaat aagtttttca gtggtgcttc cggattcatc
    19441 cctgtcagca tcacaacggc cccgataact ccaccaagag ttggtgttgc accaaaaact
    19501 tgtgcagcat tgatacctgt atagataact aggtagctaa acatcccgtt tttcaagatg
    19561 ttcatcacat cgatatattg ttgccatgtt gctgcatcaa gtgttccggc tgtgactaag
    19621 tttgctaaaa ctgcggcaat ccctgccacg atcccagtac cgacaaatgc aggaatcatt
    19681 ggcacaaaga tattagaaat gtcttttaat accgatttga ttttagatgg tttttgtttc
    19741 gatttttgtg ccgctttcat ttcttgtgcc cgttcgttta cacggtcttt tccagatgct
    19801 gatgaatttg ctgtagctgt acttacagaa gaaagttttt ctcctaattt cacgcctgcc
    19861 aaatcaacca tttgctgtgc tactttgttc actttcccag gtccgatgat gacttgaagc
    19921 tgttcatctt ctactacacc aagcactcct ggaatcgctt ttaattcaga gacatttaca
    19981 agatcatcat tgatgatctt catacgcaca cgagtcatgc agtggacaat gctttctaca
    20041 ttgcccatgc cgcctgcccc tttataaatt tgttttgcca gttcttccaa agtcagttcg
    20101 ttttttgcca tggtcttttc cccctcataa ggtccctttt acaaatccgt ttgcttcagc
    20161 taattttgct tgagcttcct ctttatcact atttgtcaaa atcatgacga tagccagctt
    20221 aacattttga tctgcttctt caaagtactt ttcagctgtt tcgtaatcag cttctgtcgc
    20281 ttgcatgatg attcgttttg agcgttcgat tagtttttca tttgttggtt tgacatcgac
    20341 catcaagtta ttgaatactt tacctatacc aatcatactg atagtagaaa tcatattcaa
    20401 gataagtttt tgtgctgttc ctgacttcaa tcgagtagag cctgtcaaaa attctggacc
    20461 tgcatcgact tcgattggga aatccgcgtg tttactgatt tcggcttgtt tattgcaaga
    20521 aatcgttcct gtgacagcac cgatcgattt tgcgtaatct aatccaccga tcacatatgg
    20581 tgtacgaccg ctagctgcga taccaataac tatatcattt tttgtcaaat tcagcttgat
    20641 tagatcttct tgccctagct cataagaatc ttcggcccct tcgacagcta cagtcattgc
    20701 ttcttctcca ccagcaatta gacctatgac catttccggt tctacaccga atgtcggtac
    20761 gcattcagca gcatctaaca cacctagtct tccacttgtt ccggctccca tataaatcag
    20821 acgtccacct tttttaaagg actcaatcgt gttagcaatc actggttcga tacttgtcag
    20881 ttctttttca accgcagcgg ccactttctg atcttctttg ttcattagtt gaacggcttg
    20941 agaaatactc atctcatcta atccaaaagt ttcttggttt ctgcgttccg ttgttaggtt
    21001 ctctaaattg attttgctca tttttatctt ccttcttttc ttataaattg atagttcata
    21061 ccagctttga tttggttgat caatggtagc tcttctttga taactttagc tactacattc
    21121 actttttcat ccgctggcaa atcatatttg gttaattgga tctcacccat atagcgcaaa
    21181 tacttttcgt tatctaaagt aatagaccct ttcatacgcg tagctgtatt tcttgctggg
    21241 ataggcggaa tctctcgaaa acgtgcatct acgcttcgta tgacatctct tgcatcgtct
    21301 tgccgattcg tatgcttccc taatatatat tcgtaaaatt cttcatctac aggttccgta
    21361 tggagcaaga ctgtctgttc tttttggaaa gaagcaaatt gctcctgaac gttttctgac
    21421 agacctgcat ctccgatgta aacaatatcc gtgttacttg ctaatagatc tagagcgcct
    21481 gcaagaggat ggatccctcg atgttcttcc aaagttggca atccttgata tagtgggcct
    21541 ctcaactctg tatctcctgg tacaaaacct tggacaagga gaccttgaat tttgagccat
    21601 tgattttttt tctgatacca ttctttgtcc agccctgttt cgggacgtgg ataataatta
    21661 tgccaagctt caatctgtga gaaatcagct tctgcttctt tcaattcatc gatatcttta
    21721 ggcgtgatcg tgctagcatt caaactgatt ttcaattgat gtgaccagtc ggcaatctgc
    21781 tgattggaaa tatgataatc cattcttaaa cctgttacac caattgcttt caaaggcgtt
    21841 agatcttcta atgaaaaacc cgctcgttcc aatgcctctc ctgaaatatc gaccatcaat
    21901 tctagtttat tctttttcgc ttcgcttcct agttcgatca atcgcttttg atatgccgaa
    21961 acatcatctt ctggtatatg catggaagtg aaaataccga caaagccatt ggatgccatt
    22021 tggcggatat actgtttctt ctcttctgac aaagaatcgt tcataaatat tgaaaagcca
    22081 aacatattat ccctcttttt ctgtatccgt cttcatttct atgactagag tatatatcta
    22141 aagaaacaaa atttcaatac ttttattaaa ataattaaat ttcatttcta aaggttgagt
    22201 ttatattatc aaaagaattg tcataaccta aaaaaggcac tgctaagcaa aagcagtgcc
    22261 ttgaaatatt ttatttaaat aacacaaaaa cataattact cataagaaac caattctgta
    22321 ttatctacca tgaatgtaaa gaacccctca ttaggcatcg gatgaaaata agcattgatc
    22381 actcttatca aggcattatg gcaaactaac agatagacat tttcttcgtc ttcgatgcat
    22441 tctttcaata aaggaacgat ccgtgcatac acatctaaga ctgactcccc atttgggaat
    22501 cgtacagcga acgctaaacg tgctttttga aagttctcat ctttgcttgg cagtccatca
    22561 taatccccaa aatccatttc taccaatcgt tcatcaacgg tcagcggcaa gctgagacga
    22621 tcagcaactg cttgtgctgt atctcttgct cgttgaagag gggaatggat gattttcgtg
    22681 attggaacag gcaaatctac taccttttct gctagtttct gtgcctgcat ctgtcctttt
    22741 tcagtcagcg gcacatctgc ccgtccgcaa actaatcctt gtgcgttcca agttgtttct
    22801 ccgtgtctcg ttacataaag catgtgattc tctccttcgt tggcaaagtt ccccttaacc
    22861 ataccttgtt gttcttgaga ttacaagggt tagattctct caagagaaat aatctcagta
    22921 gatactttat ccaggaaggt ttgatcatgt tccactagta acatggcagg tttcacgttc
    22981 aagatcagtt gttctaattg ttcttgattg aagacatcca aataattcaa tggttcatcc
    23041 catgtatata gttcagctgg ctgtgataaa gatttagcca attccacttt tttccgttgg
    23101 cccatactca tctgctcgat cttgttatga aaaacatctc tttccatccc aagctttcgg
    23161 aggttgttca aaaatgcttg gtagtctact tggtttttct ctgcaaattc cgccaacgtt
    23221 cctcgattgt cttcataatt ttggcttgca taactaatgc tcagatgttt tggctggtat
    23281 ttttctccta taaccttgcc gttgaatgcc cccagaagat aatggataat ggatgacttt
    23341 cctgcaccgt taggacctga aatcgccacc cgctgatgag gctcgattgt aaaatgaatt
    23401 ggctcgaata acagattttc ataccctaat tgaagatctt ctacgcttaa aagtcgctta
    23461 tggtgagacg cttggctatt catcgtcaaa gaatcgatat attcgatatc ttttaatagt
    23521 ttttctttct cgctgatctg ggtctccatc cgattcacga ttgctttgga tcgtttcatc
    23581 gtccgtgcag catcagcacc cactgctcct ttattcactc gtctagattc agtatcgatg
    23641 aatccgactt gtttctttgt tttatctcct tctcgggaac gagaccattc ggctttttca
    23701 gctgctgttt tctttagcct actgacttct tttttcaatt tttcattttg agccatttca
    23761 aattcatcac gaagtttttt ctgttcttca tagatagaga aattcccttg ataaagttcc
    23821 agttgacttt tttcgattgc taaaacatgg tccactactt catcgataaa tccccggtca
    23881 tggctgacca cgatgaagcc ttgttttttc tttttcaaat aagccgctac ttgttttcta
    23941 ccagagatat ccaaatgatt cgttggttca tcgattaacg ggaaatgagt gtcatccaca
    24001 aataaaagtg ccagtaggac ttttgtcttc tctccccccg atagtgtgct gaattctctc
    24061 cataagattt caggatctgt ttgcatcaat tggagctctc tttcgatttc ccatatctca
    24121 aaatccgtaa tatcatttaa cacgtaatag gttaaacgtt ctttatcttt tgtctgttgc
    24181 gggaaatagg caaattcttg ctgatggatt acttgccctt gataaggtag tttgttttgt
    24241 agaatattca gtaaagttgt ctttcctcga ccgtttcgtc cgataagtcc tagtttccat
    24301 tgtgtgtcaa aatttagatt tgcttgttca aataataatg tgccttggct gtcgtagccg
    24361 aatgtcagat tttttatttc gattttagac attttccatc acctcgtaaa aaaagaccag
    24421 tcctattttc agaactggct aaagaggatg caagggttgg atacacacaa aaagacccat
    24481 acatcgaaaa aaccaagcca atcccgaaaa tctgcacact gcttccttgt ctccacaagg
    24541 tacagtctga atgcagcttt catcaatcga cttaattttt caatgcacgg atccctcact
    24601 ttgtcctata tttgaaatta cgatagcata aagaaaatga ttttgtcaac tacttcggga
    24661 ggatggtgaa aaatctgcta agtgtctgtc ctaagatttt tgttttttct aatgtttgcc
    24721 tgtgttccat tgcttcttct aaacctattg gacccaaatg aatacttaag acaattggga
    24781 gaaaatcaga aagtccttct agctcttggt ctctacttcc gcaaatagcg attattggtt
    24841 ttcgatattt ttttgcaagc actgctacac cgtatggaac ttttccgtgg atcgtttgct
    24901 gatcgatccg cccttctcct gtaatgatga catctgcttg ttcgatcttt ttttccaatc
    24961 cagtgatttg gctgactaaa tcgaaaccag aaaccatctt cgctcccaac aaaaaaaggg
    25021 ctccaccaat accgcctgct gctccacttc ctggaatatc atctaaatcc acctcccaga
    25081 aatcttttat ttgctgagca atctttcctg cttgtttatc taagaaagct agcgtcgtat
    25141 ctattcctcc tttttgtctt ccaaattgcc aagcagctcc ttgttgacct gtatatggat
    25201 tggtaacatc tgcagcgata atcaatttta ctttagaaac aagaacgttt cttcgatcaa
    25261 aatgaagttt tttagtagat aataaaggat ttccttctgt gtacccttct aaagaagcac
    25321 ccaaggattg gagtaatcct agaccaccat cgctacaccc gcttcctcct aaagtgacaa
    25381 taatttgttc tacttcttga agcagtgcat ctttaataag ttctcctaag gcataactgg
    25441 aagcaagtcg gatagtttga tccgttggtt tatcaagtag atctaacccc aatgcttgtg
    25501 cagattcgat gactgcggtg ttttttcctt gccaagttgt caataaatag ctgatttttc
    25561 gctgacggaa taagagatcc atcccatcaa tggtacgcca tgttcccctg agcgcgtaat
    25621 agattgcttc tgcagtattt tctccgccat ctgcaatcgg cacattgatt tttcttcctt
    25681 tacgatcttc ccagccattt agaactgcct gatttagttc aaatgaagaa gcacttcctt
    25741 taaatgaatc aattgccgcc aaaatatcca tctgtatccc tcactttctt cttaagtaag
    25801 acactttttt tcattttttt caaacaaaac aatgctattt tcttccattt ttctatatac
    25861 taaaagggaa ctcattgaat aaaggagaga aaaaacatga aaatcgcaat agctggggcc
    25921 ggagcaatgg gcagccgaat cggattgatg ctacatcaaa gcggaaatga ggtcctcttg
    25981 atcgatcgtt ggcctgctca cattgaagcc attcgtacaa atgggttgat tgctgacttt
    26041 aacggtaaag aagtggtcgc aaaactgcca atctattcac cagaagaaat catcgaaagc
    26101 aacgaacacg tggacttgat cgtagcatta acaaaagcca atcaattaga tgatatgttt
    26161 tgttcgatcc aatccattat tactgacaat acttatgttt tgtgtttact aaatggatta
    26221 ggtcatgaag atgtactgga aaaatatgtg ccaaagaaaa atatcttatt tgggatcacg
    26281 atgtggacag ctggtctagc tggtcccgga aaagtcacat tgttaggtga tggagaaatc
    26341 gaactagaga acttggaacc agaaggcgaa gcatttacaa aaaaagttgt agaagtcttt
    26401 caagaagcaa atttaaatcc gatctatagc cataacgttc gttattccat ttggcgaaaa
    26461 gcttgtgtaa atggaacatt gaatggttta tgcacgattt tggattgtaa tattgctgaa
    26521 ctaggcgcgc aaaaagcggc agagagcatg gttcgaacaa tcgtatctga atttgcttct
    26581 atcgcagcaa aagaaggaat catactagat caagaagaag tgtaccaaca tattgcttct
    26641 acttatgatc ctgacaacat cgggttgcat tacccatcta tgtaccaaga cctgatcaaa
    26701 aaccatcgtt tgactgaaat cgactacatc aatggtgcca tttggcgaaa aggacaaaaa
    26761 tatgatattg ctacaccata ttgtgccttt ttgacccaat tagtccatgc aaaagaagga
    26821 atccttggcg cagaataaaa ggctctctga tgagaatcag ctgaatcagc agctggttct
    26881 ctttttttaa gcccaataaa agatcaaaaa gaaaacacaa ctctcatgat gccataagaa
    26941 ttgtgcttgt ttgtttcagt acataatctc ttcaaaatgt aggtttttta tttgttttca
    27001 acagaggaga ggtcatattc gtattgctca taaatagtgg aatcgttagt gataaatcgt
    27061 tttgcccaat tttctgcatc ataaaattcc aatagctctg ataggattgg cttaaatggt
    27121 gtatgcagaa attccggtaa ttcatctaaa tcacgttctc gaagcaaaaa aatattttca
    27181 ggacgataaa aatgataatg agcaatcgct tgattatccg tcactagttt cttttgaaaa
    27241 tacatggatt caaatgtccg caaagtcact ccttgctgac cctcccgcaa cagttccaga
    27301 atcccgcgcg attcccctgt ttttttcagg tactcttcat aagtaagata tccaggttgt
    27361 tcattccctc gatgtggaag aatgaaatag ttggtcgtaa catctctttt tataaattcc
    27421 tgcttatagc tttctgctcg ttcttttctc ccattattcg ttgcaccaaa aaatagatcc
    27481 gtctttggtt cgctagaaga aaaattcata tgtttcgaat aaaatgaact attatgtttc
    27541 agcccaagtt cttttgcttc caaaaaatca aaatgataaa tctcatcgat tgccggttca
    27601 tcttgtgcct gcttcagcat cgcctcgtgt tctgctttga agtgattcca aaaaaataac
    27661 acaatttttg cattggtaaa tgggcgcacg cgtcgagcca tctccatatc aaatccataa
    27721 tctaaaaaaa cgatcagctg ataatttgcc aactgttgtc tagctgattt aatgaattcc
    27781 gactgtagta aatcttttcc ggaccaaaca tctaaagagc ggatggaagg caaaaaataa
    27841 agtgatttat tttttgcaac tagcagtacg tcatttttgt tcatcttttc cgcctcactt
    27901 tctctgtcac tttttcctat gatagcctgt ttaaatagta aaaagccagt aaaacgtttc
    27961 ctatatttgt atgaaaattt aacatttgta tgaaaatatg atgaaataaa tcattcttct
    28021 attaaaattc gcctaaaagt tttctgaata gttgtaattg tctgaaaatt tgttatcatt
    28081 agtcattgtt aaatattgct atttattctt aatataaatt ttgattgtga atttaaaaga
    28141 aagaggtcat ttatggaaga taaaaaattg aaaaaacaac ttagctccag acatatcacc
    28201 atgttagctt taggtggagc aatcggtgca ggtctattta aaggaagtgg cgaagcgatt
    28261 gggatcgccg gcccttctgt attgattgct tttttgattg gtgggctgat tttatatatc
    28321 gtgatgaaag gtctgggaaa aatcgtttta agcggtggcg acacgcatca cggattatct
    28381 ggtttgatac gcccttatct aggtgctcat tctgctgatt ttactgattg ggtctactgg
    28441 tctatgtgga ttatcaatat catcgctgaa gctgttgcag ctgcttcctt tttgcagttg
    28501 tggttcccgc acattccagc ctgggtattt gtttttatgt tggctgtttt aactacgatc
    28561 atcaatcttt attcggtacg gttattcgca gaaacagaat attggctggc ttttgctaaa
    28621 atcagtgtca ttatcttact gatcattttt gctacttatc ttgtcggtca gcaaatgttg
    28681 ggcacaggcg ttttccctac ccttcagcaa ttgactgacc atggtgggtt tactcctcat
    28741 ggtatgaagg gaatcatcag ttctttgctt gtagttatct attcttacgg cggttctgaa
    28801 ctgattgcta tcacggtaag cgaagcagat gatcctaaac gtgcgattcc taaagcaatc
    28861 aaaggtgtca tgggaagaat catttccttt tacatcattc ctttgttttt gcttttgatt
    28921 ctttttcctt ggaatacttt agcaggcacg aatgtcagtc cttttgtgat ggtatttgaa
    28981 aaaatgaata tcccatttgc agcggatatc gtcaattttg tgattgtcct tgctttgttc
    29041 tcatctatca attcgggtgt gtatgcatct tcaagaattt tgttcttccg tttgaaggat
    29101 cgaaaaggtt cctctagaaa actagctgtt ttaaacaagc atcaagtacc gcaacgtgct
    29161 gttttatttt gtaccagtgt tctttatctt ggtgtagctc tttcttattt tgtcggtgac
    29221 aaattatttg gctatctggc aggttccctt tcgtatacag tattattgat ctggatcatt
    29281 atcagtgcgg catcctttgt actggcacta agaaaaggaa cattatggga taaaggaatc
    29341 agcttttttg cattagctgt cttaggattg attttccttg gtatcctgtt cacgaactcc
    29401 attggggtaa ctgtattgac tggcctgctt tacctgttca tttatttcag ttatcaaaaa
    29461 aagaatgatg cgttcgtatt gacgaatgaa tgaaatcgat agaaaatttt attttattta
    29521 tgtggaatag atggagctat tgaagaaagg agttgtgaca aaagtcttgt tgcaactcct
    29581 ttttccgaat aaacagtctc atgacctctt ggtaaacggt gttcaaaaac cctctgtgca
    29641 aaataattga ttgttctcca tgctcatgac atgatagaag aaaggaatga aaaaaaggag
    29701 tttgttttaa atgaaaaagt attggaagtt tttgttgatg atcggtgttt caacggtagt
    29761 tatgtttggt atgatgtact tgaatgtcta tgcgctcgat catatcttct tcagtcgtac
    29821 acgagtattc atggcgttga tgatgggtgc agtcatggca gtcatcatgc tgttgttcat
    29881 gtggaaaatg tatgaaaaca aaaagataaa tgttatgatc ttagccgcta gtcttcttgt
    29941 ttttgccggt tccttgttta tggtacgaag ccaaactact gtcaacgaca cagcttggat
    30001 gaaggccatg attcctcatc attctatcgc tatcctggca agtaaacgag ctgatttaaa
    30061 agatcctgaa gtaaaaaaat tagcggaaga aatcattcag gcacaagaag aagagatcga
    30121 caaaatgaaa aaaatgatca aagaaatgga atgaccatta tccgtccaaa taaaaaaaga
    30181 ggatgttcca gaagttatca gcttcaagaa ataagaagaa gctacttctg gaacgccgtg
    30241 aataaggggt tgtgaaaaag ctgccctgca tcaagtaata agaacagcca aacaaaaata
    30301 gcttctccta tttttcgttt ggttaggctt attaccgcag atgcaagctt ttgaacaccg
    30361 tttattaaga ggttgtaaaa tcagcgttct gacctgagta ttagagagac aaatggaaaa
    30421 atagttcctc atattttgcc attttttgag ctaataccga gggtcagctg attgaacacc
    30481 gtttatcgag aggttgtgaa aaagtcgctt agtttcgcgt attaagaaaa attttgtgaa
    30541 atggctttcc acatttttgt ataaatttgg cttaataccg agaaactggc ttttgaatac
    30601 cgtttattcg taaaagggat tgtgacaaaa gtcttgtcac aatccctttt tatgttttta
    30661 ttgttctaat tgcgctgtct tgcttactgc ttcttgcggt ttcacaaatt tttttgagat
    30721 tccccaacct gtgaaggcac tgaccatcga aaacacagga gaaagcaaac tgaaaaatac
    30781 gaatggcaag taagtgagtg taggaatacc aaatgtactt gctacgaaac ttccggcaat
    30841 tccccaaggc actaagtagt tgattactgt tccaccatct tctagcgttc tacctaatac
    30901 agttggatca aatcctgctt tttcataagt ttctttaaat gcattaccag gcagaataac
    30961 agataggaat tgttcaccaa taaaaatatt tactccgata cttgtcatca atgttgtaaa
    31021 aatcaaattt ggtgtgttcg tcatctttct tgatactcgt tccatcacgg ttgagatcaa
    31081 gccaaattcg atcaacaatc cacctaatga caaagttaga ataatcaatg acacagtagg
    31141 catcatactt tcgattcctc cgcggctaag cagtgaatcg atttgttggt ttccagtatt
    31201 tgaaacaaac cctgattcga tgaccccagc caacttcgtt aaggaagttt gtgggttttg
    31261 aataaaaatc attcctactg ctacagcgat attcaacaaa atcgttaaaa ttgccggcac
    31321 ctttttccat gcacacagta acattaaaaa taaaggaatc agtgaccaga ttgaaatagt
    31381 aaagtttgct tctagaacat cagtcacttc acgaatagat gaaagacttg cggctttact
    31441 tgtgtgtcct aaaatcatga ataaaaagaa agaaacaaca aatgccggga cagttgacca
    31501 catcatatgc ttgatgtgtt tgaacaaatc ggcatcaaca atagctgctg ctagatttgt
    31561 tgattcggat aatggagaca tcttatctcc aaaaacggca cctgaaacaa tagctccaac
    31621 aaccagcgct ggatttaagc ctagtgttgt cccaataccg aaaaatgcaa tcccaatcgt
    31681 tgacataaca gtaaaggcac tccctacagc gctacctacg attgcacaca caacaaatac
    31741 agaagggaca aaccactgga cactgatcaa tttgaaccca atgaccatta gagttggaat
    31801 gatccctgct tgtatccata cagcaatcaa tgaaccgact aaaataaaaa taaagattgg
    31861 gatgattcct ggtttgatgc cattgatgat tccttcgtgc agccaatctg tcgggtatct
    31921 ttttatcact gcatacaaca tgaccattcc gatcgctgct aagatcgtga tattaggtga
    31981 gacctttaat ccgacaacgc caatcgcaat gcctaaaaca ataaccatta atacaagtgt
    32041 tgcttctaaa aaacttggtg ttcctttttt tcccatgata atctctcctt ttttagttgt
    32101 tcttatgttc taaaaaagtt aagatatcgg attactccgc cgcaattcat ccgcgattcc
    32161 tcctttataa aaataaaaag acctgtttta aactaaggac gaatgactcc gcggtaccac
    32221 cttaattaaa aacagatctg tttttcactt tcaaactttt attcaaatgt atggactttc
    32281 catgtaattc gtcaattagg cttgatcggt tcacagcgac caccgacttt ctgaacaaaa
    32341 cacctaaccg ctactgcgtg aaaagttgac ttgtacgaag tttaccttcc ataagatcat
    32401 ttgtcaatga aaaagaaaat attttttcat ttttctgaaa attattttta taactttcac
    32461 acacaagatt attttttact agaaagtagc gccctcttgt ttttttcttg ctactatttc
    32521 ttgatgttct tgcttgattc tttctaatag ctttggctct ttcaacagat caagagctgt
    32581 attggcgagt agttctgctg caatcgcaat agaagcaagg cctttgtcac ttttagcagc
    32641 agctttgaat tcttctgtgt gtccggcaat atatgtctca gagattgcta ccgtaggctg
    32701 gattgttggt atgacttggc tgacatttcc tacatcagaa gaaccgagac ttgttctttg
    32761 ttccgtttct atttcttcat ctggaacacc tgcttctttt gcatgctgga agaataagtc
    32821 atcaaaagaa ggagtaacga tgacatcatc aactgcattt tggaacaatc caaactcaaa
    32881 agtcgtgccc gtacttatcg cagcacctcg tacgatattt tccacttttt catatacttt
    32941 atctaatgtt tgccgatttc ctgcacgtaa atagaaacgt ccagcagcgt aatctggaat
    33001 gacgttggca gctactcctc cgtctgtaat gatcccatgg atattgacat cttttggcaa
    33061 ttgcaagcgt agagcgttga ttccattaaa cacttggatc aatgcttcca aagcatttac
    33121 tcctttttca ggtgctgctg ctgcatggga agcgacaccg taaaatttga tgtcgactgg
    33181 atcattcgct aaagattctg tcgttttccc ataacgaaaa gctggatgga cgcataacgc
    33241 tacatcgaca tcctcaaaaa aaccttctcg aacaaagctg cctttagctg atccgttctc
    33301 gcccccttct tcccctgggg tgccatatac acggatttct ccaccagttt catcaatgaa
    33361 ttgcttcact atgctggcgg ctaatacgga gtaagtacca aacaaattat gcccgcatgc
    33421 atgaccaata cctggtaaag catcgaattc tgccaaaaag gcaattgtgg gaccgggttt
    33481 attggaaata taacgtgcat caaaggctgt tcggtgtcca gctacttctt tttctaccca
    33541 aaacctttct ttttctaatt gtttaatcaa cgctgctgag gaataaaact catagttact
    33601 tacttcagga tgttcgtgga tatctagagc aagtgcttga tattctggta aacgatattg
    33661 gattagatcc ttcaattggt ttgttgagat tgttgttgtc ataaaaaatt cctcctatgc
    33721 tagtcatttt tcttattttc tcccgaatgt ttcccatgca ggcacgcttg atccttttga
    33781 tgttttctcg attactttga ctgtgtcttc tgtttgataa gcgtctacta ttttttgata
    33841 cgttttattg ttttcatctt cttttcttgc aacgatgata ttcacataag gacgtgcatg
    33901 gtcatccact ggttctaaga agatggcatc agaagcagga ttaaatccag catctacagc
    33961 tacaccgcta ttgatcactg aaatgtctac atctgacaaa gcacgtgctg tttgggaagc
    34021 atctaattca gaaatgtcta gattttttct attctcggta atatcagaaa cagtgggcgc
    34081 ttgtcctttt gccttatcca ctttgatcaa tccagcagtt tgcaataaca gaagagctct
    34141 gccgccattt gtaacatcat tagggattgc tacttttgct ccgtctttga tatcagctac
    34201 atccttcaaa gtgttagaat aaattcccag cggtgcattg acagtatttc cgatcgatac
    34261 taaatcagtt ccgtgttctt tattgtaatt gtctaaaaag aattgatgtt ggaaagaatt
    34321 caaatcaatc gatccatctg ctaaagccac atttggttga ttgtaatctg taaatttcac
    34381 gtattccaaa ttaatgttct cctttttcaa acggtctttc acgttgtccc atacatctgt
    34441 atcttctcca ataatcccta gttttacgat agtttctttt ttgtcagttg tatctgcttt
    34501 tccttggcta caccctgcca accaaataat tgctacaaat gtaatgacta caaaacgaat
    34561 aatttttttc attttttctc ctccactttc aatgtgtaat ttttttaatc agttgattac
    34621 tgataaattg acttaaaaaa actaagatta gaatcaataa tgtagccaca atcgttacat
    34681 ctgtttggaa tcgattatac cctctcgata tagcaagatt ccctaatccg cctgcaccta
    34741 ctgctccagc catggtagtc agtccgatca cgttgatgat agtcaacgcc gagacccgaa
    34801 tgataccagg caaaccttct aacaaataca cacgtaaaat gataccgatt ggactggttc
    34861 ccatcgcttc tgccgcttcg atcaccccag gatcaacttc tagcagtgcg ttctcgattt
    34921 gacgagcaaa aaacggaaca actccaaaaa tcaatggcac taaagctgct ttcgcaccaa
    34981 tcgtcgttcc aactaagaaa cgagtagtca atgctaaaag agaaagcaag ataatgaaag
    35041 ggatggaacg aatgatattg atcagcttat caagtatttc aaatagcaga cggttagcta
    35101 gtaatccatt agggcgtgtc actactaacg tcacacctaa gatgattcca atcatcccgc
    35161 caatgaatgc tgtccaaaaa gacatatata gtgtttgctt cgtcgcttcg acaaattcat
    35221 ccggaatcaa ataaacattg ggcaaatatg ttttaaagaa atcagtcatt ttatcttcct
    35281 ccttcgatca ctttgatacg actatctaaa tcgttttttt gtaaaatatt tatttttaca
    35341 ccagatttga tcaaataatc caatgctttt ttccgctgtt tggtttctcc agctaaagta
    35401 acgatcaaac tccctaacgg cgtttcttgt aataactcta cattgccata taaaatattc
    35461 gctgttactt gatatttgct gtacagatga gcgattagag gttcgttcgt ctgatttcca
    35521 atataactta attccaccag ccatttattg gcgatctgat cggcaaaagc agaatgggca
    35581 atgatcgttt ctaatgcttg gtcaagatga gtagctgttc gaataaaatc tttggtcaat
    35641 tcttcttcag gattgctgaa gatctggatg ctgctacctt tttcaacgat tcttccatct
    35701 tccataaccg ctaccttgtt gcagatttct ttgacaactt gcatctcatg agtgatcagg
    35761 acgattgtta aacctaactg gcgattcaat ttttttaaca atgcaaggat ctgaagggtc
    35821 gttttcggat caagtgcact ggttgcttca tcacataata ataccttagg ttcattcgcc
    35881 aaagctcgtg cgattgctac tcgttgtttt tgtccccccg acagttgttt aggataagca
    35941 gatgcttttt cttccaaacc gacaagttcc agtagttcat tcactttttg acgacgttcc
    36001 tgtttcgatt ttccagaata ctttaaagaa aaatcaacgt tgtcaaaaat agttcggctt
    36061 tccattagat tgaaatgctg aaagatcata ccgatggcct ttctttcttt tcgcaattct
    36121 ttgggagaga gctgactcag attcgtctga ttgacaatga cttctcctgc tgttggtttc
    36181 tgcagcaaat tcatcacacg aactaacgta cttttccctg cacctgagta accgacgatt
    36241 ccataaacat cgcctttttc aatcgttaaa tctacagaat ctactgcctg tatctctttt
    36301 tctttttgtt tgaaacatac agaaacatct cgcaattcaa tcattaaaat tcctccttat
    36361 ctaaaaaaag cgtcctcaag aaaatgaaaa tgtcattttc ttgaggacgc ttttttgcgt
    36421 gttaccacct catgttcaag ctgtgttcac acacaactcc tcttcaagta cgatcatact
    36481 ctagcaagat atcggtcgca gccgtcatcg ccttacatct atgctcggga tgaattgctc
    36541 gatggccatt ttccaatagt cgttccttgc ttcttctcag ctaccgaagc tctctgtcaa
    36601 aggttcttct atcgtactta ccatttcaat gcaaataata ttcaaaaaaa aagtcctttt
    36661 actaacataa actatgtcag taaaaggacg acgtatcgcg gtaccacctt ttttcggaag
    36721 tttccttccc tcaagcccaa catctcaaaa agagagattg gcgttcgttt taacggtcga
    36781 acagttccga atttgcctac ttatcgacaa attattctcc aaggccattt tcagcttttc
    36841 ttacttgact cttctcacca gccagagcct ctctgcaaag tttccaaact tactttcctt
    36901 ttcaacgaaa tcgatatttt gttgttggga ttaatctaca tgaggaaaac tgaaaagtca
    36961 agtacgaaat tcaaattatt ttttctatat ttatttttct gtttttttat ttaacatttc
    37021 aataacagtt cgaagatctt ttccttccgc aagaagtttc aatttttcct tttcttcgac
    37081 ggtataattt cggacaaaac tggaatcagg tatcaaaaca acgcctaatc ctgctcgtga
    37141 agcagctgtt gctcctacta aagaatcttc cactgcaaag gctgaactag cttctaatcc
    37201 tgttcgttcc aaagctgtca gataaggaat cggtgaaggc ttgttctccg acacttcgtc
    37261 tccgaatgta aacgtgtcca agtaatcagc taatttaaag tgatccaaga tatctgttgc
    37321 tcttttcgta acagtggtcg tagcaatgcc tagtttcata tgacgttctt ttaagtctgc
    37381 caatatttct tttgcatatg gttttaagtg gatggctccg cttgtcagct gttgataaaa
    37441 atattcttca cgcttcgctc ggacttcctg tactttttca gggctacctg ctgctttcac
    37501 taaaatatca aaactttgtt tccagttttt tccgccccaa gcgtcaacga tttcttttgg
    37561 gatatggata tcaaattgct gaaatcccca aagccagcca tcacgatacg ttttttctgt
    37621 gtcaactaac aaaccatcta aatcaaatat tgcacctttc atctatacat taatcctttc
    37681 caaaacaata cacatagttt agcacgactg gtccaaaaag aacagaagca aagaaccagc
    37741 cttctcgttt ataagagttc ttggaatcga cggatataga ttttcttcac agctgtcaca
    37801 agcgccagat aagcgatgac tgtagcaaat aaccataacc agtaattgcc aggaagtggc
    37861 atcaagccta attcagcacc aaaacttgta aaaggaagga cagaaccgac aataattcct
    37921 aatgtagtga taacaaacat ggcaaatgtt gcgttgcttt ggataaatgg tactttcggt
    37981 gtacgcagtg catggagcac taaggtttgt gtccatagtg attcgacaaa ccatcctgca
    38041 tggaataatg cgatgaaaat cactcgctgt gaactatcca atgtatggaa acttccgccc
    38101 actacagcag gacaaataac aaaatacatc aacaagtaag tagtaatatc aaatatcgaa
    38161 cttgttggac caaagtaaac catgaattcc ccaatactag atgcattcca tttttttggc
    38221 tcgtccaaat attctttatc catccgatcc catggcaagg aaatgcagga aacatcatag
    38281 atcagattca aaaacaaaag ttgtaaaggc agcattggta aaaatggcag gaacgtactt
    38341 gcaatcagca cggaaaacat attgccaaaa ttagaacttg ctgtagcctt gatatatttc
    38401 atgatattcc caaaagtttc tcgtccagaa agaaggcctc tttccaaaat cgtcaaatct
    38461 ttttctaaaa ggatcacgtc tgcagattct ttcgcaatat ccacagctgt atctacagaa
    38521 ataccgatat cagccacttt cattgcagga gcgtcattga taccatctcc taaaaatccg
    38581 acagtatgac catttttacg taaagctgtc gtcaaacgtg ctttttgctg aggattcaat
    38641 tttacgaata cttcatggtc ttcagctact tgtgctaatt catgatcact catttccgag
    38701 attttctcac cggtaaccaa ttcattgatc tctagaccta cttgacggca cactgaacgt
    38761 gtaactaatt cgttgtcccc agtcagaact tttacagcta caccatgttc tttcagagct
    38821 ttcaacgctt gtttcgttgt ttcttttggt ggatcaagga aagcaagata accaatcaaa
    38881 accatgtctg actcatcttt gactgaaaat tctccaacga cgcttggatt ggtcttttgt
    38941 gcgacaccaa tcactcgtaa gccatcttca ttaagtgact gtacttttgc aagtacggct
    39001 tcttttcgtt cttttgttaa tggtgtaaca gtaccgccaa gatcaataaa tttagaaatg
    39061 ttcagcattt cttcaatcgc accttttgtg atcatttgtg ttttaccagc tggatcagca
    39121 accacaacac tcatacgacg acgttcaaaa tcaaaaggaa tttcatccac tttttgataa
    39181 ttgatcttat ctgtatctaa agtttctgtt gcttcatcaa tgatagccac atctaacaaa
    39241 tttttcagcc ctgtttgata gtagctattt agatacgcat ggcgcaaaac acgatcatct
    39301 tcatttcctt cacaatccat atgatattca agaatgattt tatcttgtgt caatgtcccc
    39361 gttttatccg tacataacac atcgattgca ccaaagttct ggatggcatt caaatttttg
    39421 atcactgttc cttttttggc catcacactt gctcctttga ccaaattcgt cgtaacgatc
    39481 attggaagca tttcaggtgt tagaccaact gctacagata gtccaaaaag aaaagcttct
    39541 agccaatccc cttttgtaag cccattgatg acgataactg ctggagccat caatgacata
    39601 aatttgatca gtagcatgga tgttttatgg atgcctaatt caaagcttga ttgaattggt
    39661 ttttcagata gcgtttctgc tacatgacca aatagtgttt catttccaac agaaacaatg
    39721 attccttccg cacttccact gatgacatta cttcccataa agacaagatt ttcgtaactt
    39781 gtttcgcttt gctgatcgtc ttcacatact ttcgcatgct tttctactgg atagctttcc
    39841 cctgtcaatg ctgcttggga aatgaataaa tcctttgcgg acaataaacg catatccgct
    39901 ggtatcatat cccctgctga aagccgaaca agatctccac agacgatttc ttccatagga
    39961 atctctgtgt actttccatt acgttttaca gctgccgtta ctttcacaag tgatttcagt
    40021 ttttcagccg cttgattgga acgtacggac tgaatcaacg tcattgtccc gctgacgata
    40081 accatagtga agataatggc tacaccgaaa agatctttat ctccaggagc tgctaataca
    40141 tattccgtga tgaatgaaat aattcctaat gcgatcaaca ctaatgtaaa tggcgtgatg
    40201 tatgctttca atatttctac aatgaatggt gtttttttgc catatgaaat cgcattttca
    40261 ccgtaatttt ctcttgaacg ttcgatttgt tcttctgtca atccatttgc tgatgcatgg
    40321 aatagttcaa ataattcttg tttcgttttt ccagcaaaag ctgcatagat tttttgtgta
    40381 tctttctttt tttccatctc aatctctcct ttgtgtccaa aagacagctg ttctcgctgc
    40441 ttttggtctt tagctattca tcggatcgat agagaaaaaa ctgaaagggg ctgagaacag
    40501 atagataata gccctggcct ttcctctaga tccttgtttt tcgaatgact gtcatccatt
    40561 tgttctcatc tcctttacta agtaatttta attcatgact tccaatcatt tttcgaatag
    40621 ttatttttcc aattagacca cctccttttt atttttcacc gatggggatt tgcggcaaca
    40681 aaaaaacctc tcgccaaata ctcagcgaaa ggtttgaaaa agcatattaa aaaaagcttc
    40741 tcagatctca tcgttgagtt ttgacactgt acaacgtaaa aagcagatac ctgcttttag
    40801 ctaccttatg aaaagcctta tctcgacaat tcctgttcta cccattggcg tctctcgacg
    40861 tttttgggca gtagcctatg tttgtatagg agcctcacct aacaaatctt attcggtttt
    40921 ccttcgttaa tataacaact aaaaaagagg atgtcaaatc aattttccat gtttttcata
    40981 ctttttttaa aatacacacg ttatattcct gtctcacgcg gttttatttg tctcattttc
    41041 cacctcccgc tataatagaa atatagtagg aaacgaggtg ctgttatgga aagaacactt
    41101 gttattatca agccagacgg cgtgagacgc catttagtcg gaagcatcat ccaacgtttt
    41161 gaagcaaagg gactggccat tgctgaaatg aagtttgaaa ctatgactcc tgaattagca
    41221 aaagaacatt atcagcactt gactgagcgc agtttttttg atgaactgat cgattacatg
    41281 acttccggtc ctgtcgttta tcttgtgctg gtcggcgagg aagtgatcga tatcgtccgt
    41341 aagatggttg gagcaacaaa agctgccgat gctgttccag gtacgatccg aggagactac
    41401 gcgctgccgg ggactgaaaa catcattcac gcttctgatt cccgtgatgc tgcggtaaaa
    41461 gagatcgccc gctttttccc gccattcgat ataaacaaac cgtctgaaaa agcggcgaag
    41521 tgatacaaat tctaaactgc tggtctagtt gctgggttca gcaatggcca gcagtttttt
    41581 ctctaaggac ctccgttgat tctttcctaa catatattcg agcactgtga agaattcttg
    41641 gtagtctttc gtcttttctt cccctaaagc agcagaaatc aatctttgat aataatctgc
    41701 catcaatgtt tcatagatca ctgtacttct ttctttatgt gctaagctcc gtttcatatc
    41761 ttcattcaca ctacgtgcct ttttcaaccg accattttct atataaaacg aagtcaggtt
    41821 cattaaaaaa gtaaagagat actgctcatg attgttcaac tgtgctaatc gtcgcattct
    41881 ttttttgatt ttcaaataat tgttctcaat gaaccgatca ctgaatatcc aaggaaaatc
    41941 agctagaata gatagttcaa attgaccata gtctggtatc tgcatcaagt attcttcaat
    42001 gattcggcat tcataacgta aaaattcaaa ttctgtctca gatacttctg ttttttcgac
    42061 catgtgaaga ttcaaaacca aataatacag atcttctgtt ttcttaaaat gcctacggtt
    42121 attgctgatc tctttataag gatcaaagct gtcttcttgt acccgatcta gcattcgtct
    42181 ttttttcttt aactttattg gttcatccag ctggtttcgc atccattcat attctgcaag
    42241 tgtcatgttc attcgctcta aaaatgatct caatgttaca aatgacattt ttttcactga
    42301 atttgtctca atcccgacta gagaagtctt aaaacagatt ccttccgcta attgggactg
    42361 tgtcaacttc ttgttgactc gaagtttctt gatcaattca ccatcataca taatagttct
    42421 cctttttaat ttaaattttt ccacattcaa taaatagata cgttaaaaag gaaaaataca
    42481 cgaaaaaaat aaaaaaatgt ttttttcata aaaaatacca accttcaagc attagaatgt
    42541 tgtctaacta ctgaaggttg gtttgattgt ttattgatta tttttttgct gttcaacgtc
    42601 tgttcttgtt actggatata agttggttgt tgttttatta ccattttttg aaaagacact
    42661 tgtcgaatgt tcgccttttt gcttttcgat tgcttcatta cgttccgctt catttttata
    42721 gtcatatttt ttcggatcaa tcgtctcaaa tccgtttggc acataaaacc gcaagagatt
    42781 ttcctgattc agcttatctg aaagacttaa cgcagtcttg actttttcct gatctttgga
    42841 gatttcctca tcgattcctg ctgctttcgt atcgatgatt tctcctgtct gattattgta
    42901 agcttttcct cctaggacgg tgtatttggg tgtcacaaag ttcccatttc gaaaagcaac
    42961 tacttgatca tgctgagaag ataataagtc tgtaccaaaa tgaagataat ctttatcatc
    43021 gattcccaat agatgtagta atgtcggcaa aacatcgatt tctccaccgt attcatgatt
    43081 gactgtccct ttagtataac caggcatatg gatcatcaat ggcactcgtt gcatctgtgc
    43141 gttgtcaaat tcatcccatg tatctggatc tttaccaaga gcgcttgcta aatctttatt
    43201 atctgtattc gagatcccaa aatgatcccc gtaaatcaca aagattgaat tttggtaaat
    43261 accagatttt ttcaaatacg taaaaaattg ttccaatgat tgatccagat aatgtgccgt
    43321 tcgaacataa ttatctactg tgctattgcc agtattcaaa gatggaaagt cgaaattctt
    43381 gtcatccgta taataaggcg tgtggttggt tacggaaaga aatttcgtgt aaaacggctg
    43441 ttgtagatgc tcaagatatt gggcagattc tctgaataaa tctttatcta atatcccata
    43501 acctaacgtt tcgtcggatt catcaaaata agatcgatca aagaaattgt cataacctaa
    43561 gtttttatat acatgatctc tattccaaaa actagctaca ttcccatgga aaacagcgct
    43621 tgtatagcct tgcttttgtc caaggatcgc tggtgcggct tgaaagacat tgtctgaccc
    43681 aagttctgtg aataatgagc cttgaggtaa accaaatgtg ccagtttcca acatattttc
    43741 agcatcactt gtctttccct gtcctacttc atgaaagaaa ttgtcaaagc tgatcgttgc
    43801 ttgattctgg aaaatactat ttaaaaacgg tgtgacttct tgtccgtcta ccttcatatt
    43861 aatcaaaaac tgctggaaac tttctaaatg gagaacgatc acatttttcc ctttagcgat
    43921 cccaaatgtt tcgggatttg gctctgcata atgtttcttt gtataatcta aaacttcatc
    43981 aatcccatta ctgcttgcat gcgcgcgaac actgctagtc attcctgttt tgattccgtc
    44041 ataaatagta tacgcatcga ttcctagata tttgacaata tatgaacggt caaatgttcg
    44101 ctgcagcaat tgtggacggt tggcttcgct cagcgctaga tttcctgaaa aaataagccc
    44161 tgaaagacag gtaacagcga tagccatcgg tttgccgaca gggttgcttt tgataggtat
    44221 tttcttgacc ttcaaccaaa ccagtagccc aatgaacaca gcgatatcca gccagtagat
    44281 gacatcatgg ggcttcatca aagaaaagga gcttcctgac aatccttgcg acactttcga
    44341 aaagcctaat acagatttga ctgtaatgaa atctgtgaat tcccgataaa aaataatatt
    44401 caagtacaac aaaagcgtat ttaaaatatc aatgatcaaa agaatagcta acgctggctt
    44461 tggcttttta atatacaaag aaaggccaaa aaacaataag gtagtcgcaa ttgggttgat
    44521 ccacaagata aagtactgga tcgtaccttc cacacctaat gaaaaatctg catagtaggc
    44581 aatgatcgtc ttcagccaga aaaagaaaac agctgtcaaa acgattgcta aacgattttg
    44641 gcacaatttt ttaagttgtg tcacgtatat cacttctctc tattcacatt ttttcttatt
    44701 ttgctcctga aaaatgaaaa tttcctaaaa aagttgttat cttaagattt ttttattctt
    44761 tctaaagatt attccgtcca cttttcacag cataaaaccg ctgcgatgta agcgattaaa
    44821 ctaatgaaga gataaaagtc ttgtggtgac cgcttcactc cacggtattc aaaagccagt
    44881 ttctcggtat tcgtacaaaa aaagaggctg tgacaaaatt cttgtcgcag ctccttattt
    44941 cttgatgcag gacagctttt tcacaacttc ttccttaaac ggtgttctcc tgccaactcc
    45001 tcggccacaa gtcacaatat ttataaaaca tgagaagctg ttttttgaaa ttgttccttg
    45061 tggctcagag ttaaacggca ggctcaagac ctcttgatac acggtgttca atcagctgac
    45121 cctcggtatt agattatgtc aggacgctaa ttttacaacc tcttggtaaa cggtgttcaa
    45181 aagcttgcat ctgcggtaat aagcccaacc aaacgaaaaa tataaggagc tattttttga
    45241 aattgctcct tgtggctcag agttaaacgg caggctcaag acctcttgat acacggtgtt
    45301 caatcagctg accttcggta ttagctcaaa aaacggcaaa atatgaggaa ctattttgcc
    45361 gtttgtttct ctaatactca ggtcaaaacg ctgatttcac aacctctgtt tttcattgtc
    45421 cataggattg atattgtcct tgtgatgact cattcgtaat aattgaggct tgattttctt
    45481 cacttcccgt tatcgtttgt ccactgccag aatctgaagg acttgttcct gtcgactcgt
    45541 ttttttgaga agagacagtt gttttcttga cttgttcatt tgtctttttc cattccgcta
    45601 aacgatcggc gaccactttt ttgtctactt tttcagaata agcggtgatc acttttccat
    45661 ttttcaaacg ggctactttg tcgccatcat gagtcaaaag caaaacggtc aaatgcttgt
    45721 ctttaaattg atattgtctg agagaaatcg cactaagtac gtcatcgata ttaataaatt
    45781 gattttcttc ttttcctttt ggcaaataaa tgtccaattc gcctttttcg taattggcag
    45841 ttattttata ctccgcccac caataagttg agaattcttt tttgaaatta tctactgatt
    45901 ctttgcttgc tacgattttt tctgtttctt tctgagcaag atctgctgtc atttttcctg
    45961 aaaatgctgc ggataaaata agcagtaaga aaaaaccgaa taaccaaaag agaagaaacg
    46021 gtcttttttt cctcatgctt tcctccactc ctatttaatt ttgactattc tattatatac
    46081 aaaaaatgaa atagaaagac aaaaaagttg aaaaagatcg taaataattg aacttctttt
    46141 tcacaaaatg gtaagaatgg agaatttcac gcatttgctc tcaactattc tttcttaagc
    46201 ctcaaatccg tttttatctg atacgtcttt gaaccaatga cccgattttt tgattgttct
    46261 ttttccatct tgtgctaagt ctactgaaat aaagccatat cgattcttat atgcattggt
    46321 ccacgaccag ttatccatac atgtccacat atgatagcct aaacaattgg caccttcttg
    46381 aatggcttga tggacatatt tcagatgaga ttggacaaat tcgatccgat aatcatcgtg
    46441 gatcatgcca tcttctttga taaatcgtgc ttcgttttct acacccatac cgttttcaga
    46501 aataaagcag tcgatatttc cataatgatc tcgtacattg atcaaaatat catagattcc
    46561 ttgttcatag atctcccatc cgcgataagg attcatttta cgaccaggca tttcataatt
    46621 gtcgaaataa tcctcaggca ttggaccgtt tttagtatcg attggtgttt cttttgcttt
    46681 tacccggcgt ggctggtaat aattgatacc taaaagatct actgtatttt ctttgataac
    46741 cgtcaaatcc tctgcatgga tcacaggcat gagatcaagt tcttttacta tctcaatcaa
    46801 ttcacttgga aactcgcctt ttacagctgg atcaaggaat gaacgattga agaacgcatc
    46861 tgctatttgc gctgctttaa catcttcagg gtttgattcg tctcttggat agcttggtgt
    46921 cagattcaag atgataccaa taacaccacc ttgctccatt tcatggtaag atttgatggc
    46981 taacgctgaa gccaacgctt catgatagcc aacttggatc gcttttttca tatctgactc
    47041 ttctggataa tgccatcgat ataaataacc tgcttcgact ggaacgattg gttcattatg
    47101 agtaaaccat ttttttactt tcgaaccaaa caattcaaaa caacttttgg catatttttc
    47161 ataggcttca accgtttctc ggttcaacca tccgcctttt tcttgcagat acatcggcat
    47221 atcgaaatga tacagattca caaagggttc gataccgttt tcaatcaact catcaaaata
    47281 acgatgatag aaacgaacgg cttcttcgtt gattgttcca gattcatcag gtatcaaacg
    47341 gctccattgg atagatgttc gaaatgaatt atgcccagtc tgtttcatca actgtacatc
    47401 ctcttgatac ttcgtataaa cttgcgaggt tttttcaggt cctacttgat caaagaactt
    47461 ttgcggttct tttttgtacc aataatcaaa aatgttctct ccttttccat cgcctgaaat
    47521 ccttccttct gtttgtgggc cacttgctgc agaaccccac caaaaatttg ctggaaattg
    47581 atattttttc atcaaagcac ctctttttct tttttagttc gttttagttg attccatgta
    47641 tgatattttc catcacaatc actttttcat tttcttcctc ttcttttttg attcgtttta
    47701 acagctgttc tgctgctcgt tccccgattt tatctgttgg tggcgtgatc gtgattttcg
    47761 gaaggatact cagatcgttt ttatctaaat aatcatagtg actgaacgca atatccttcc
    47821 cgattctgac accttcttga ttgaaacatt cgatggcacc aatcgacata ttgtaattgc
    47881 tgacaaaaat agcagttgcc cctttttcta ataatgcttt tgccccgtaa tagccgcttt
    47941 ttctagaata gtctcctgta aagacctcta attggatcga tggatcattt tggaccgctt
    48001 ctttggctcc tgctaaacgt tctcttgcta cgtagtctgt ttgagtggca gcaataaatc
    48061 cgattttttt atgtccttgt tcaccatgat gagcgatcac ttttgctaca ctttctcgat
    48121 cattcactaa tattgtatca atacctgctg gtccttctgg acaattcaat gcgataactg
    48181 gaatactcat ttttgtgagc atttcaaatc cagaccactc ttcttcggat aagaagacaa
    48241 tcagcccatc gatcacatgc ttcatcaggt attcaatttt ttgttcaatt ttttctggct
    48301 gatcggcaaa cccgcttaat aataagctat acccattttc ttcagctact ctttcgatcc
    48361 ctgagacaac ttccgaccca aaacggctgg aaatcccgtt tatcaaaagt ccaatagaga
    48421 agcttcgatt attcttcaac cctttagcaa tgatgttttc tttatagtcc aacgctgaaa
    48481 tcgcttctgc tatttttttc atgttctttt ccttcagttg ctgaccattc aagtaacggg
    48541 aaactgttcc cactgaaaca ccagccatct tagccacatc acggatcgat gccatacatt
    48601 ctcactcctg ccagttacat ttgatttctc tttcttgttg ttcgattatg atgaccgcat
    48661 tctttgcata gtgttgcttg tcatcaatat ccatataact aaagtcttca gtagagcaac
    48721 ttcctctcac tattaattat acttaaacaa gtatttgaac cggttcattt ttaatatagc
    48781 atttttttaa aagattgcaa cactttttta aaacgctttc tgaaagtggc ggattttttg
    48841 cctttttaaa attttattct aaaatttact ctatttgtgg gtgttttgtg cgtttttctc
    48901 ttccatccgt ttgaagtttt acattccaat ggtataattt ctttatccta tcaaatgggg
    48961 gaagtatttt gaagaaatta atcgtactat ttattttgtc tgcgggactt ttgacattga
    49021 ctggctgtga tttgtttggc ggctctgacc aatcctcgga cgaaacaacc gattcttctg
    49081 tcttaaaagc ggaaaaagca gataccacca acagtgtata tacgctaaaa gtacgtaaag
    49141 atatggattt atccgcggga cagttgacat ttacagataa aaaaatggaa tggacacgca
    49201 cgtatcagac acaaggaact gattcttctg aatcatctga agaaaaaaca gtgctgacag
    49261 atatcaagat cactaccaaa gatgacgaat atattatttc aggaaaagaa aataaaaaag
    49321 aaacaacagt catatttaca aaaatcggta attaccgttt gaaggatgag gatggcaaca
    49381 tctacagtct atagtgccgt ctgttggatc ttcttttgtt tctccccttc ttttctgcta
    49441 tagtaaagaa gcaagatgat tgtaaaggag acgaaatgga tgatcgatag tcctgattat
    49501 tgtacatgta ataacaacaa aaatatccat acagaattta atgaccaagg aagcttgagc
    49561 atatgcgaca actgtcacaa actagtcaaa gattcattta aaacatttga atcttatcct
    49621 gttcaaaatt atgtaaaaag tagaagaaga taaacaaatc caagcaaaac tcactatggc
    49681 tgatttttat gaacttcaaa ctcagcttct tcctttgatc aagcttcatc agtaaaacaa
    49741 acagtggatc atttcagttt acaaatcaaa gagtaaagat ttatttattt caaatatttg
    49801 aatataaaat aaccaaacga tagaaaggct tattctacat cacgtagta
//
LOCUS       DADLIO010000013        48346 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.013, whole genome shotgun sequence.
ACCESSION   DADLIO010000013 DADLIO010000000
VERSION     DADLIO010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 48346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48346
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.013"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            125..1168
                     /locus_tag="JOX41_000883"
     CDS             125..1168
                     /locus_tag="JOX41_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HAY6448647.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(1230..1694)
                     /locus_tag="JOX41_000884"
     CDS             complement(1230..1694)
                     /locus_tag="JOX41_000884"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HAY6448648.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            1940..2887
                     /locus_tag="JOX41_000885"
     CDS             1940..2887
                     /locus_tag="JOX41_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAY6448649.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(3098..5170)
                     /locus_tag="JOX41_000886"
     CDS             complement(3098..5170)
                     /locus_tag="JOX41_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAY6448650.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(5103..5480)
                     /locus_tag="JOX41_000887"
     CDS             complement(5103..5480)
                     /locus_tag="JOX41_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HAY6448651.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(5609..6169)
                     /locus_tag="JOX41_000888"
     CDS             complement(5609..6169)
                     /locus_tag="JOX41_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAY6448652.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYLSLRFLG
                     YFTKEPTIDPEDSYFWMINNFIATLP"
     gene            6319..7611
                     /locus_tag="JOX41_000889"
     CDS             6319..7611
                     /locus_tag="JOX41_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAY6448653.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(7671..8789)
                     /locus_tag="JOX41_000890"
     CDS             complement(7671..8789)
                     /locus_tag="JOX41_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HAY6448654.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(8803..10224)
                     /gene="arcD"
                     /locus_tag="JOX41_000891"
     CDS             complement(8803..10224)
                     /gene="arcD"
                     /locus_tag="JOX41_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HAY6448655.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(10470..11591)
                     /gene="mnmA"
                     /locus_tag="JOX41_000892"
     CDS             complement(10470..11591)
                     /gene="mnmA"
                     /locus_tag="JOX41_000892"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HAY6448656.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            11995..12594
                     /locus_tag="JOX41_000893"
     CDS             11995..12594
                     /locus_tag="JOX41_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphatase"
                     /protein_id="HAY6448657.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(12732..14018)
                     /gene="efmA"
                     /locus_tag="JOX41_000894"
     CDS             complement(12732..14018)
                     /gene="efmA"
                     /locus_tag="JOX41_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HAY6448658.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(14289..14633)
                     /locus_tag="JOX41_000895"
     CDS             complement(14289..14633)
                     /locus_tag="JOX41_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HAY6448659.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(14770..15906)
                     /locus_tag="JOX41_000896"
     CDS             complement(14770..15906)
                     /locus_tag="JOX41_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAY6448660.1"
                     /translation="MKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGRHAH
                     EKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIEHPA
                     VLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLMPIK
                     EIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKRDGV
                     NIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLILDTL
                     EANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNIEPS
                     HVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(16095..17069)
                     /locus_tag="JOX41_000897"
     CDS             complement(16095..17069)
                     /locus_tag="JOX41_000897"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HAY6448661.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(17149..18024)
                     /locus_tag="JOX41_000898"
     CDS             complement(17149..18024)
                     /locus_tag="JOX41_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HAY6448662.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            18154..20061
                     /locus_tag="JOX41_000899"
     CDS             18154..20061
                     /locus_tag="JOX41_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HAY6448663.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(20602..23880)
                     /locus_tag="JOX41_000900"
     CDS             complement(20602..23880)
                     /locus_tag="JOX41_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HAY6448664.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(24151..24696)
                     /locus_tag="JOX41_000901"
     CDS             complement(24151..24696)
                     /locus_tag="JOX41_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAY6448665.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(24708..25400)
                     /locus_tag="JOX41_000902"
     CDS             complement(24708..25400)
                     /locus_tag="JOX41_000902"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HAY6448666.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(25419..25703)
                     /locus_tag="JOX41_000903"
     CDS             complement(25419..25703)
                     /locus_tag="JOX41_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448667.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(25716..26279)
                     /locus_tag="JOX41_000904"
     CDS             complement(25716..26279)
                     /locus_tag="JOX41_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAY6448668.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            26507..27169
                     /locus_tag="JOX41_000905"
     CDS             26507..27169
                     /locus_tag="JOX41_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     protein"
                     /protein_id="HAY6448669.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            27293..28489
                     /locus_tag="JOX41_000906"
     CDS             27293..28489
                     /locus_tag="JOX41_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HAY6448670.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(28590..29966)
                     /locus_tag="JOX41_000907"
     CDS             complement(28590..29966)
                     /locus_tag="JOX41_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAY6448671.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(30003..30869)
                     /locus_tag="JOX41_000908"
     CDS             complement(30003..30869)
                     /locus_tag="JOX41_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HAY6448672.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(30958..31983)
                     /locus_tag="JOX41_000909"
     CDS             complement(30958..31983)
                     /locus_tag="JOX41_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAY6448673.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(32001..32675)
                     /locus_tag="JOX41_000910"
     CDS             complement(32001..32675)
                     /locus_tag="JOX41_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAY6448674.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(32859..33752)
                     /locus_tag="JOX41_000911"
     CDS             complement(32859..33752)
                     /locus_tag="JOX41_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAY6448675.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(33826..35523)
                     /locus_tag="JOX41_000912"
     CDS             complement(33826..35523)
                     /locus_tag="JOX41_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAY6448676.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(35516..36829)
                     /locus_tag="JOX41_000913"
     CDS             complement(35516..36829)
                     /locus_tag="JOX41_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAY6448677.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(36829..40866)
                     /locus_tag="JOX41_000914"
     CDS             complement(36829..40866)
                     /locus_tag="JOX41_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HAY6448678.1"
                     /translation="MVVDERIDNQELQENETDTEDSAEIQRSEENEMEKLDEPIVPSG
                     QALQRIQRQLFNGILERLGPTATQDPYEYIYPSGEVENEQHRYPKFTTNDYTKVLGNW
                     TQSNERYQGDKGSPYDGENLIDDSDYTNGGANWRNYDYATNNGSTAGEEDRNVPAQTV
                     QLWGNERNFENSYLDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEKK
                     EISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMVN
                     FYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETLY
                     KDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDVL
                     FRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGSS
                     NNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAIG
                     RNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVSP
                     FGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYKF
                     SPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSSS
                     IRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFETK
                     MPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEYT
                     SGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNIN
                     KLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDGK
                     YVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRLY
                     DNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTLD
                     GAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQPL
                     HLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIIDG
                     VLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPNDS
                     SLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTLK
                     VEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYILL
                     AAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(40879..41337)
                     /locus_tag="JOX41_000915"
     CDS             complement(40879..41337)
                     /locus_tag="JOX41_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAY6448679.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(41635..42153)
                     /locus_tag="JOX41_000916"
     CDS             complement(41635..42153)
                     /locus_tag="JOX41_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAY6448680.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(42155..42771)
                     /locus_tag="JOX41_000917"
                     /pseudo
     CDS             complement(42155..42771)
                     /locus_tag="JOX41_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
     gene            complement(42768..43631)
                     /locus_tag="JOX41_000918"
     CDS             complement(42768..43631)
                     /locus_tag="JOX41_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAY6448681.1"
                     /translation="MTANDGLFQKDQCESANKKILSYVLMTVIGIILIIPLLWMVFTS
                     LKPMEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFI
                     AYGFAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGN
                     AFNIFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWN
                     DFLGPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFI
                     EGMDLTGGSKG"
     gene            complement(43618..44529)
                     /locus_tag="JOX41_000919"
     CDS             complement(43618..44529)
                     /locus_tag="JOX41_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAY6448682.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(44570..45904)
                     /locus_tag="JOX41_000920"
     CDS             complement(44570..45904)
                     /locus_tag="JOX41_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAY6448683.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKIFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            46112..46942
                     /locus_tag="JOX41_000921"
     CDS             46112..46942
                     /locus_tag="JOX41_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HAY6448684.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(47186..47435)
                     /locus_tag="JOX41_000922"
                     /pseudo
     CDS             complement(47186..47435)
                     /locus_tag="JOX41_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(47626..47820)
                     /locus_tag="JOX41_000923"
     CDS             complement(47626..47820)
                     /locus_tag="JOX41_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448685.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
BASE COUNT        13913 a        10335 c         8613 g        15485 t
ORIGIN      
        1 tattcgaaac aagaggtcgt acaagacttt tgtcacgacc tcttgttctt ttgtcaaaat
       61 actggtttag tgctactatg ttcgagtatg cttttagtat ttattgacga aaggaaccga
      121 tcaaatgaaa tcattgtcac atccaataaa atctgtaaag gattcagcgg tccgcgaaat
      181 cttacccggt ttactgcttt cttttgccat cgctgccttc agcaggcttc ttgctattta
      241 tctgccacag ttaggtggag cgactattgc tattttattg ggtattttat taggaaatac
      301 tttttttaaa cagcctgttc tagcaatcgg cacaaaattt gctgaaagca aactattaga
      361 attctctgtt tttttactag gtgcaactgt cacagctcaa acgattgctc aaattggtgt
      421 aaaaggaatt gtttttgtgt tactgcaaat gtcagtcact atcatcggtg cttacttgat
      481 tggtaaaaaa ctgcaattca gcgatacttc ttctttgatg atggctggag gaaacgctgt
      541 ttgtggttct tctgctattg cttcaatcgc cccttccatc catgcgaaag aggaagaaaa
      601 aggacagatc atcacactag tcaatctact gggtactgtg atgatgttga ctctcccttt
      661 tcttggatta cagttgtttg gtggaaatct cattgaaaaa agtgcacttt tgggtggtac
      721 actccaatct gttggtcaag tagtcgctgg ggcaagctta cttgacaatt ctgttgtcga
      781 attcgccatg ctatttaaga ttctacgtat tatgatgctc gttgttgttg tctatctgtt
      841 tgaaaaattc atgcacaaga aacaaccagc tctgtttgaa acgccaactg atacgcagaa
      901 aaaacgaaaa ttaccgcttc cttggtatgt attagggttt gtgatctttt gtttggtcaa
      961 cagcttgttt tctttacctg tagttattga ccaatcggca cattttatca gcagctggtt
     1021 tgagatcact gctttagcgg caattggtct gcgtttagac tttgcaaaat tcatgaaaga
     1081 aggtacacgc ttcttatctt atggattagc tgtcgggctt ctccaaacag tgatggcttt
     1141 actatttatt tggctgatca aagtttagaa tgaacatgaa aaaacagttg tgattctcgc
     1201 atggaacaat gtccgaatca caactgtttt taattttgca gatatccttc taacaacaac
     1261 aattggcgtt tgatttcaac cccatctatt gcgtttccca tatatcctgt cagttttcca
     1321 ttttgcccga tcactcgatg acaaggaata acgattggca atggattggt tcgatttgcc
     1381 tgcccaatcg ctcgcacagc tttcggacta tcaacagcaa cggctacttc tttatacgtt
     1441 cggatttctc cataaggaat ggtcgacaaa gctttccaga cattttgctg aaaaggcgta
     1501 cctctcttta tagataaagg aacatcaaat tcttttcttt ttcccgcaaa atattcttca
     1561 aactgttctt gtgtgcgcgt taaaattcgc tgattcgctg attcgctttc tgaaattggc
     1621 tgaaaagata cagcagtcaa tccggattca tctgcatcta accataaaaa gccgataggt
     1681 gtgtgtattt tcattttgtt tgctcctagt caatagactg gaacttcctc ctttttctct
     1741 atccaaaact acttgccaac taataaaaat tgttcttaaa agtttgataa accgaggaaa
     1801 catggtaaac taaatacgtt agtttacaaa aagaatacct gttcttttac gtaaaatcaa
     1861 attttaaagg tgttatttaa ggtttattaa attttgaatg taaaccatat ataaacatac
     1921 gattgaaagg atagaaacga tgaaagtatc aattgttgtc ccatgtttta atgaagaaaa
     1981 aactgttcct cttttttttg atgaggttga aaaattcaaa ggtgcccatg agttcgaata
     2041 tttgtttatt gacgacggat caaaagacgg tacgttagca gcaatcaaga agctagcctc
     2101 agcttatcct tatgtccgct ttgtctcatt ttccagaaat tttgggaaag aagcggctct
     2161 gtacgctgga ttgcaagctt ctacaggaga tttagtgacc gtgatggatg ttgatctgca
     2221 agatccgccc gaactgcttc ctgagatgat caaccggatc actacttctg atatcgattg
     2281 tgtcggcacc cggcgttcga ctcgtgaagg cgagcctgcg atacgcagtt tctttgcgaa
     2341 aaaattctac cagttgatca ataaaatcag cgatacagaa atggtcgatg gcgctcgtga
     2401 tttccgcttg atgactcgtc aaatggtgga tgccgtccta gaattaacag aatacaaccg
     2461 attttcaaaa ggattattta gctgggtcgg atttaaaaca gaatatattt cttatgaaaa
     2521 ccgcgaacgt gtggctggcg aaacatcttg gtccttctgg aaattattca actactcgat
     2581 tgatggtatc gtgaacttct cggatgcacc gttaacgatt gcttcattta tcggcgcttt
     2641 gtcttgtgtc ggttctggta ttgcaatttt gttcattatt ttgcgggcat tgttgtttgg
     2701 tgatcctaca tcaggatggc cttccatggt ctcgatcttc ctgttcattg gtggaatcca
     2761 attgttatgt cttggaatca tcgggaaata tattgggaaa atcttcttag aaacgaaaca
     2821 gcgtcctgtt tatatcataa gagaaacaga aaaagtgaag ccaaatgaat tgaagcctca
     2881 ccaataatat acgtcaaatg aagtaaacat ttttttaaat gaaaaaggac tgtgacaaaa
     2941 gtcttgtcac agtccttttt tccgaataaa tggtgttcca gaagtagctt cttcggaaat
     3001 aagccgaaat ttcacaaaaa tttgagaagc aattttcgta aattccttct tatttcttga
     3061 agctgaccac ttctatcaca acctctttca tatcttatta cttcttcatt gctgctttta
     3121 gtgctgctgc taatgggctt tcttctggtt cttctgcttg tgcatatttt ttcagcaagc
     3181 gtcgttcttc atgtttggtc attttcttct tctgctcttt tttatcaagc aatttttctg
     3241 tcgttccatc gtatttacaa cggaaataag caccgttttt accttcgatg atttccattt
     3301 tccggtgaca ttgcgggcat cgatgattag agacttttgg atcttttctt ctgcggtagt
     3361 tgcaatctga attggtgcag acatagattt tgccgtcacg tgtgtttttc tcgcgcagat
     3421 tggccccaca ttctgggcat ttcttttggg taatcgagaa atcttgatat tcttgtttgc
     3481 ttgatttgat ctcattcacc aagcgttttg tttctttttc gattccattc aagaaggttc
     3541 ctgcttgttt ctttcctgca gcaatagctt caaggtcttt ttcccagctt tctgtcaaat
     3601 ctggtgttac taaagaggga tttaccaata ctaataattg cttaccttta ggagatactt
     3661 gcagtccttg aggggtacgt tccatcagtt cagatttgat tagtttctcg ataatctctg
     3721 cacgcgtagc tggggttccc agactgtatt tttccatttg accaagcaag cttgcttctg
     3781 acaatggttt aggcggtgca gatagttctt ttttgatggc gaaatcggga ttgattctca
     3841 ttcctttttc ccatttgact gtttccgtct cagtttcagt ttcgcctttc catcctgctt
     3901 ggacgacacg attttgccga aaaatgaatc gttctttacc aaattcaacc gtaacttttg
     3961 tttggctgac tttatggggt tgagcaaaca gtcctaaaaa acgagagaca atcatttgat
     4021 agatttttcg ctcttcatta cttaattttt cataacgtgc tctgttttca gttggcaaaa
     4081 gtgcatggtg atcggtcact ttactgtctt ggaatacttt tgtctgttgg acgatggctc
     4141 cgtttttcaa atactgcttg acctcaggag caaagtcgct gactgcttgc aatcgttctt
     4201 tcatcgtact tttcatgtca tttgtcagat atttgctgtc tgtacgcgga taagtaacga
     4261 tcttatgggt ctcatacaaa ctttgtacaa gacttaatgt tttctttgca gaatagccat
     4321 agcgttgatt ggcttctctt tggatctctg ttaaatcata aggcaatggc gcagattccg
     4381 tttttaattt ttcttggact tctgtgacag ttcctttgct tgtactgatc aattgaacaa
     4441 gtttttgtgc ttcttcttgt gtttttaaag caaattgatt tttttgaagc attttggctt
     4501 gttcttttcc agcttgcaac gtgatcgtga aatacgtttg tggacggaac tgctcgattt
     4561 tcttttcttg gtctctcact aatgctagtg tcggtgtctg cacacggcct gctgataaat
     4621 tatccgcgta cttcacagtt aaggctctgg tcacattcaa tcctaccagc cagtccgctt
     4681 ttgcccgggc aagagcagat tcatacaatg catcatattc tttcgcaggt cttagttgct
     4741 tgaatccagt tttgattgct ttatctgttt gagaagagat ccataaccgc ttcactggtt
     4801 tattgaaatg cacatactct aagatccagc gagcaacaag ttccccttct cttccggcat
     4861 ctgtcgcaat gactgcttct gagacatctt ttcgctgagc cagctgcttg attgctttta
     4921 attgatgtcc tgttttagga agtggtttga ttcctagttt tttagggatc attggcaacg
     4981 tgtccatttg ccagctctgc cattccttat tcagatcttc cggcattttc aatcctaata
     5041 aatgaccaag ggcccaagta acgatcacct tgggtccttc ataataattt ttgtgctttt
     5101 gattagcacc aagcaccttg cttaggtctt tcgcaacgct tggtttttcc gctagaatta
     5161 gttgtttcat aaaattcctt tctgctttct actgtgatgg gctgatgatt tttcaacaac
     5221 gcaagtccct tgtattgctg taaatcatcg tcacactctt cacaccagcg ctcatctccg
     5281 tcattccaaa aggcgctgag aaagttactt tttgcattga tatattcata attttgatgg
     5341 atttcgttcc attgtttttc gtacgcttgt cgtgcttctt cgaaagactc gaatgtttct
     5401 tcttcttcaa tatcttcttc ccagtcttca aaaaaccacc aaggctcatt gtccccgaac
     5461 atggtaatta cttgatacat actcgtgctc cttctttcag cttttctaga ctcatcttag
     5521 tcacttttca agaaagttgc aagaattttc tcttataaaa gggtcattta atgaacatct
     5581 taaaattgtt acaaatgaat ctgattgttt aaggcaaagt agcgataaag ttattgatca
     5641 tccaaaaata gctgtcttct ggatcgattg ttggttcttt tgtaaagtat cctaaaaaac
     5701 gtaaggaaag ataaccgtgg atcatactac gaagttccct gcttcgatga actttttctt
     5761 ctttcgttaa ttgaaaagcc tcaaatatct gcaaaatgat ctgattcgtt tcatggattc
     5821 catctaataa aacagcttca ttggtatgcg gtacactgat cagtaactca tacactgctt
     5881 gatttgaaaa agcaaaggat cgataagttt ctgcatagat ctgcagtgct tcctgaccac
     5941 tttttcccac aagagcccgt cgcagctggt cattaagttc ctgcagaagt ttcgctgtta
     6001 gcgctgtttt gacatcacga atatttttga aatggttata cagcgaggga gccttgatat
     6061 ccaagcgttt ggctaaatgc tgaaaggtta tttgctgaac atccatctct tctgctagtt
     6121 ctcgaaagca gtcgatgatt ttctcttgag acagatttct ttttttcatt tccatgtttc
     6181 ctctcataaa ataaatcctt cactctttca gtttaccacg aaaaagaaag agaaaaaaga
     6241 gactttcatt gataaactac atattgtagt ttataataaa gagctgtaga tgaaaatttt
     6301 cagaaagaag gagtctaatt ggctgcaaga ataaaggaaa aattatttag gaaaagagaa
     6361 acttgggaac aaaacttgtt tgtcttatgg tttggaacat ttatggctgg tatcggattt
     6421 agtttagtca tgccttttat gtcactttac atagatacgt taggtaatta tagtacgtca
     6481 caattgaact tttggagcgg attgactttt tcatctactt tcttggtgac tacgcttatc
     6541 tctccttggt ggggaaaatt agccgaccaa aaaggaagaa aattgatgct gttgcgtgct
     6601 tcattaggaa tggcaatcgt catttctttg atgggttgcg tgactagtgt gtatcaatta
     6661 gtcgcattgc gtctgcttca agggattttt tctggttata tcagtaatgc cactgccctt
     6721 gtcgcaactg ggacgccaaa agaaaaaagt ggtcaagttc ttggaacctt agcaactggt
     6781 tctgttacag gaacattact tggaccgctt cttggcggga tctctgcttc agcgtttggc
     6841 tatcgcccta cctttttcat tacagggatc atcttatttt tcgtcttctt gttgagtctg
     6901 tttttcgtcc atgaaaaatt tgtcccagtg aaaaaagaaa acatggtttc tgccaaacag
     6961 attttcaaag acttgaaata tccacacgtc gtcatcggta tgttcgtcac aacgatgatc
     7021 atccaagcat ccaacaattc cattagtcca atcatcagtc tgtacattcg ccaattgctg
     7081 catggacatg ggaatgttac gttgatcagc ggaatcattg cttcgatacc tgggattgcc
     7141 actttgatag ccgctccaag atttggtcgc ttaggtgaca agattgggag tgaaagaata
     7201 cttgcgattg gtttgggttt tgcgattctg gtttatatcc caatggcatt cgtcacgaat
     7261 gtttggcaat tagctgcctt acgttttttg attggtatct ctgatgcttg tctgctccct
     7321 gctgtccaag cattgatcac aaaatattcg cctcatcaag ctgctggacg gatcttcagt
     7381 tataaccaat ctttccaagc aactggtaac gtagtagggc ctatgatcgg ctccagtgtt
     7441 tccagtgcat ttggttatcg cggcgtcttt ctttcgactt ctcttcttgt tttggtcaac
     7501 ttcttgcttg tacgacacaa tacacaagag atccatcagc aagaaactgc agaagaaaaa
     7561 gcttcaggag tctccatagc ttcagggcac tctccttctc atagacaata agcgtaaatg
     7621 aaaaacactg cttgaacagt tgtcacagac tgtccttgca gtgtttttgt ttaggcctgt
     7681 tttttcaaga actcagataa gaggaataat cccttttcca aggtttcttt tttacaacag
     7741 taacctagtc gggcatgctt cggtaaatca aaggcacttc ctggtactaa tagtactcct
     7801 gtttcttcta ataaattgat acaaaatgtc tggtcatctt cttcgatggc taatttaatg
     7861 aaagaagtag agacgtaatt gggagcgaca agttcaactt tcggttcatt ggctacccat
     7921 tgttttaaaa tcacaaggtt ctctgtaatg atctttttgt ttcgcgccaa tattttttct
     7981 ttattcttca atgcatgtac agcaagatca tctgacagga ctccgccgca aatcatcgtg
     8041 tagtctcgat actttcgaaa aacttctgcc aactcaggtc cagtagctgt ccagccaata
     8101 cgaatacctg gaatggagta ggttttggat agggaattgg ttgctatacc tttttcatag
     8161 acatctacga tcgacaagaa ttcaccttta tccgttaaag gcgcatatac ttcatctatc
     8221 aatacatatg catctactgt acgagcaatt tctgcgattt tttctaaagt tttccgatct
     8281 agcaatgtgc ctgtaggatt gtttgcacta ttcaaacaga tgatttttgt ttcaggtttg
     8341 actaaggctt ctagctgttc taaatcaaac tgccaatctt cttcttcctt caaatgaaca
     8401 aagtcaacag cggcacctaa agatttgggg atgtcatata attgctgata agtaggaagc
     8461 atcgaaacaa catggtctcc tgcttccact aacgcgtata gagctaaaag attagcacca
     8521 gtcgctccat tcgtttgtaa gatgttttcc ggatcgacgg tttgataaag agaagcgact
     8581 tcttgtttga aaacatctga tccttcgatc cagccatagt ccaatggttc gtttttgcgt
     8641 ttttcgaaaa atttacttac gctagtccca tctaagccaa cgagttcgtc taatgtcaat
     8701 gcttcgatcg agctttgtgc aatatcatat accgctttct tttcccattt atttagccat
     8761 tcttctacac cgaaatttgc gattttcatg tttctttccc ccttatatct tgatccagcc
     8821 tacagcaagc aacccgattg aaagcagtgc ggccacacaa atcagcccaa tcattacttt
     8881 ttcttttccc gtaatttgat gtttggtttc acgacaagcg atccagtaga agcaaaaacc
     8941 aggaagatag gcaatactac ataaaaggac ataagaaaat cctgctaaaa tgatgcccat
     9001 caattcaaaa actacagcaa tcccaccgat cactacttgt tttttgattc cttcttttaa
     9061 agaaaactgg acttgataga tcccgacaag tagataacaa atcaaaattg ccgctgtaca
     9121 taaagaatag gcaaattgat aggcataatc agtaactaag aaagtcaata agaatagatt
     9181 agtcaagatt gcagtaacaa ctaacgaata agttggggca ttttttttat tcgtttttcc
     9241 ccaacctttc ggcaacagac cgtctcgagc catcaacatc gttgtttctg ctgggagcat
     9301 cgtccaagac aaccaagaac caatgatcga aataatcaag ccgatattga tcagcgctgc
     9361 tccccaattt cccacgattc cttttaaaat atttgccata gcaggttgtg aaatagttgc
     9421 taactcttct tgagataaga cgccgtatgg caagatcgaa gcaaggatat agataaacaa
     9481 taaacaaagc agaccaatga tcgatgcttg ctgggcttct gaacgtttct tcgcgcggtt
     9541 ggctaaaaca cttgcgcctt cgatccctac aaagacccac atcataacca tcaaacaacc
     9601 tttaatctgc aaccagatcg ttccttgctg ccctgttcca ttcactagat tatcagatac
     9661 gttaccccaa aaatcagcag tgaatatatt cactttaaat gcgataaata caaatattaa
     9721 aaataggaat aatggcacta atttacagat cgtcacgatt gtattgatga cgctcgctcc
     9781 ttcaactcca ttgtttacta ataaagtcag accccaaata aaaatacttg caaataaaat
     9841 agaaggaaca ttttgtccac ctttgaatat cgggaaaaat tctcccatgg cgctcatcag
     9901 catcgttgca aaagcaacat ttcccagcca cgcagacaac cagtaacccc aaccactgat
     9961 gaagccacct aatttaccaa atgaagcttc cgcgtaaccg aaaataccac catctagatc
    10021 tggacgcttt tctcctaaat gattcagcga taataccaaa gctaaaatac caatcccaac
    10081 gattatccat gaaaggatcg ctggccctgg agctgcagaa ctagccagat cacttgtgat
    10141 cccaaacaca ccgcttccga ttgacgaact gacaaccaga gcaaccagtc cccatttgct
    10201 aatacccgtc gatttctttt ccatttccat caccctcact tataaaattg aacaaatcac
    10261 ttgcaaaaga ttcccttcta ttttgcaact gctcttgctt aacaaaaagc aactttattc
    10321 atattattgg atattatgaa ctttttacac aagtatttca agtataaaat gaataaaaat
    10381 taattttatt gcaaaaaaac agctatgcta tccaaaagaa aaggtgtttc ttttgttagc
    10441 catagctgtt ttgattcatt taatatcgct taaacgtatt gtaaaacttt tgtttcttga
    10501 tatgcgtggt cgatcaaacc accacccaga cattccattc catcataaaa tacaactgct
    10561 tgtccaggag tgattgcacg tacaggttcg tcgaatacga cttctgcacg attatcatcc
    10621 aataagcgaa ctgtcacagg aacgtcttgc tgacgataac ggaatttcgc tgtacacttg
    10681 aattcttttg gcattggttc attcgtcgta aagtggattt cacttgcatc caagcttgtg
    10741 gcatacaatg caggatgatg gaacccttgc cccacatata atgtgtttgt cgctagatct
    10801 tttcctacaa caaaccaggg ttcttgcgaa tctcctccgc caccgatccc tagtccttga
    10861 cgttgaccaa tcgtataata catcaagcca gcatgttgtc ctttgacttc accatcaaga
    10921 gtgaccatat ttcctttttt tgctggcaga tagttgctca aaaattgttt gaagttcttt
    10981 tcaccaataa agcagattcc cgttgaatct tttttcttag cagtcgcaag gcctgcgcgt
    11041 tcagcaattg cccgtacttc tgatttttcc atgccgccta gagggaacat cgtttttgaa
    11101 agctgttctt gtgataattg gctaaggaag taagtttgat ctttattatt gtctactcca
    11161 cgaagcatgt ggaccacgcc gttttcatcg cgagtgactt gcgcataatg tccagtagct
    11221 acataatcgg cgccaagatc cattgcataa tccaagaatg ctttgaattt gatttctttg
    11281 ttgcacatca cgtctgggtt aggtgtacgt cctgcgcggt attcggctag gaaatattca
    11341 aatacacgat cccaatattc tttttcaaaa ttcacagagt aataaggaat cccgatttga
    11401 gcagctactt tcgctacatc cttataatct tccgtggccg tgcatacacc gttttcgtcc
    11461 gtgtcatccc aatttttcat gaatattccg atcacgtcgt atccttgttc ctttaacaaa
    11521 agtgctgtta cagatgagtc gacaccgccg ctcatcccta cgacaacgcg tgttttgctg
    11581 ttgtctgtca tgatatcacc atcatttcaa ttagattctg aaacatctac gagttgaagg
    11641 tcgcaacttt tcagtatttt acattatacg tcatatttct gaaaatttca tcccttaatt
    11701 atcaagtcgt aaaaatactg ttctactgga cctattcagt acacaaacat gatagtcaac
    11761 caaaaaatca ctcatctttt gagcattcga tataaaaaat tggcatactc ataaaaaggg
    11821 ccagcctttc ggcaataagg aataatttta taaattgtga aaaactattt ttcaaaattg
    11881 cttcttatcg cttaaagctg cacgtctcat ttacaacctt ttctttttag atgttatgag
    11941 ttgctcagat aagtgatttt gtttactcta agaaaaaagg gaggcaaaag atacatgaat
    12001 tactttatca gtgatatgca ctttttccat gaacgcttat taggaaaaaa cgactttgct
    12061 ccgcggctct ttgcaaatgt ggatgaaatg aaccaacagt tgatcactag ctggaatgca
    12121 gtaataaaag aaaccgacca tgtttatcat ctaggcgacc ttgctatgca tccgcaatat
    12181 gaaaaagcaa atgcagaaat tttggaactg gtcactcaac tgcaaggaac aatccacttg
    12241 atcaaaggga accatgacag tcgcgctttt ttccgttatt tagaaaaaaa tgatcctagg
    12301 cttactgacg gaagtcccaa attttatttt tatgatgtag gtgccatcgt taaattcgac
    12361 catcaacaat attacttgac tcattatccg atgttgctcg ggcctaacga cactatccgc
    12421 aatcttcatg gacatatcca tcattacagc gtacctatcg agaacgatgt caatgtaggc
    12481 gtagacgcac cggaaagaga actcttaaag gaaaaactac catttggcac tccgttatct
    12541 gagcaacaaa tcaaagaaat ctatgaagca aagaggaagt acgataggtc gtgaaaaaac
    12601 tgccctatat caagtattaa acaaataaag ataattactc atatttttca tttgagtagg
    12661 cttattgcca caggaacatt aggatcagaa atggagttgt aacaagactt ctgtcacaac
    12721 tccattccat actattcgtc tttttgctca tggtgttctt ttaccagttt tttctgtaat
    12781 tctttatcat aatttcgggc agctgacgtt aaaaataaaa cgattccgca taataaaatc
    12841 ccgattccgg aaaacaagaa cattttttct acccctaaac gatcagctaa tggtcctgca
    12901 aataataatc caattggacc tgccaggttc atcaaagagt tgaagttccc taagacacga
    12961 cctaaaacat tcgattcata actctgctgg atcattgcca tcagcagtgt attgaaatat
    13021 ggcgttgcac aacctgctcc tgcattcaag ataagaaagt acaagaaccc ttgactatcg
    13081 tttggaacca atccgcttgc accgatcgtc aggcccataa tgatgtaggc tataataata
    13141 ggtttcattc ggtctttcca tgttcctata aaactgatca gtgcaccgcc taagagcatt
    13201 ccgactgcgt agactacttc cactgctccc gcctgtccaa cggaaccacc aaagtaatct
    13261 agcgtcatca atggatacag actgattgct ggcatgaaca acagcatcac aaatgcacca
    13321 ttgatcgtta tgtaccataa ccctttatta tccatcaatt gctgcagccc aaattttgca
    13381 tctttaaaaa tagtaagcgg aacttccaat atttcaggag aaacttttgg gatcttcaca
    13441 aaaatcaata agccgacacc aaaaactgcc cccaatacat ctaataaaat aaggtaattg
    13501 acaggaacga ctgaaaacaa agccgcacct agagctggcg caatgatgaa attcgctgat
    13561 tggaccattc ctaactgtcc attcgtcctt gttatgtgag aagatggaac gattgtcggc
    13621 ataatcgact ggatcgttgg catttggaat gtttgtgcga ccgaacgcat aaacaaagac
    13681 acaaaaacta gccaaatcgg gaaggattct gaaatcgttc cgactactgc taaaataagc
    13741 gcgaaaatcg ctacaataat atccgtgaca atcaaaagag cttttttatc ccagcgatcc
    13801 actagcggtc ctacaaatgg gcttagtaaa accatgggaa tcattcctag taaagtagca
    13861 aaactcaaaa ttgtcgccga accggtttct cttgtcaaat accagatgat cgcatattgg
    13921 acgaccatac tagtgattcc tgacaaaaac tgtcccgata aaaagaacaa ataatttctc
    13981 ttccaattcg ttaaaacgac cgactgttca ttttccataa acatccctct tttctttttc
    14041 attttgtata gcgtttgcac aacaatcatt atacgggatt cttttttcaa aaaatacctt
    14101 tttccctaaa taacaatcgt ttcaatttaa atttctttac ttagaaacaa taaatcagca
    14161 aaatattaaa aataacaaca tgtgttaaat ttaaaaataa aaaagacaac taatttgcgt
    14221 cgtccttaca aagttagtca tctaacaata ggccgtttca aaactagttg tctttttata
    14281 tccacagatc attcgacttt ttcgaataac ccacggctaa tcatcccatc catcagaaaa
    14341 taaaatttat cttggctcat tttctgtttt ggatctttga aaatattgac tgctttcaat
    14401 ccatttgctg tagtgatcga cattttcaat gtttgaatat cttttgatac agtgattttt
    14461 aatttgaatc cttctttgct ttgcggcgtg gcatctaatg gtcggatcaa ttgataattg
    14521 cctccgtttg tttctgtaaa tccattatcg cgcaatgtat atctttttgc atcaggatgc
    14581 aaacgatagc taattggtgc gcccagtacc gttgctgttg tttcaaatgc catgattttc
    14641 acctcgataa aattagtttc tctttattat aaaagtttat cctgattttt actaggtttt
    14701 tcagttaagt tccctaaaaa atgaaggcgt tctctcagac atctgttcat ataagaatga
    14761 cttcactagt tattttttga cagcacgaac taattgatca aggaaatact ggatgtcgtc
    14821 ttcggtattt cccaaaccaa agctgatacg gatggattct tttagtatcg gtgtatcttc
    14881 tccatacatt gcttctaata cgtgtgaagg ctcgatattt cctgctgtac aagctgaacc
    14941 agtagaaata gcgaccccat taagatcaag cttcatcagt agcaaatcat ttgcttcgcc
    15001 aattaagcga agattcaaca catgagggag tttattcgtt aaatcaccat ttacttgata
    15061 agggatttcg tttgcttcta atgtatcaag aatcaattgc tggaatcctt tatatttgtt
    15121 gttacgtgct tcacgttctt caggtgacag cagttcaact gcttttgcca taccccagat
    15181 ccctgctaaa ttttctgtac ctgcacgccg cttttcttcc tgctccccgc ctaaaagcaa
    15241 tgcagggata tttactccgt ctcgtttata taagaaaccg acgccttttg gcccattgat
    15301 tttatgagca gagatactta ataaatcgat tcctaattct tctggatgga tcgtttggtt
    15361 tccgtacgct tgtaccgcat ctgtatggaa ataagctgga tgatccgcta aaagttcacc
    15421 gatttctttg attggcatca aatttccgat ttcattgttc ccgtacatca cagagaccaa
    15481 gatcgtatct tctcgtaacg cttttttgac ctcttcgatc gacagattcc ctttttcatc
    15541 tacaggcaga tatgtaacgt caaacccctt tgtctctaaa tatttcatgg tattaagaac
    15601 agcaggatgt tcgatagctg tagtgattag atgtctgcct tctttttgac gcgagaacgc
    15661 tgtttctaag atagctgtat tatccccttc tgttccccca ctgttaaaga tgatctcgtg
    15721 aggttttgct tgcagactgt ctgcaatgat ttgtcttgct gtttccaatt tttcatgcgc
    15781 gtggcgacca aatccatgta tgcttgaagg atttccaaac gtgtcttgca tgattgccgt
    15841 catcgcttca attacttgtg gatgcatggg ggtagttgcc gcatgatcca gataaatagt
    15901 tttcacttca ttcatccctt ccaaattatt gctaggcaca ttctagcata aaatagcgaa
    15961 caaaccaaag aagagctcat ttttgtctag aggacgtttc atgggcatag aaaaaaggag
    16021 ctgtgacaaa agtcttgtcg cagctccttg aagctgctca cttctgtcac aacttctttc
    16081 cctctttttt ttgtttattc gaattctttt tcttccagac ggaataacgg actcatcggt
    16141 gtattttcat ggatgcgttt gaccgcttca cccattaatt ctgaacatgt aacgattgtt
    16201 aagttttctg gatgacgatt ttcttctgtg aaaacagaat cagtgataca aatatctttg
    16261 attggtgcat tgtctaaaat acttttcgca tgatcggaca ataatccatg tgacgcacag
    16321 gcatatactt cttttgcgcc gttttctttt aatacatttg ctgctcgtgc aagcgttgct
    16381 cctgtgttca agatatcatc taccatgata catgtctttc cttgaacatc accgatcaca
    16441 taaccaccct cagttgaagc atcatctgca tgatctacga tggctaatgt gctgttcaaa
    16501 tattctgaaa gactacgtgc acgctgaaca ccgctgtttt ttggcgaaac aactacgatg
    16561 tcatctcccg tcagacctaa ttgacggtaa taatgagcaa acaacggcat cgtaaataaa
    16621 ttatctacag gaatatcaaa gaatccttgt acttgaaccg tgtgcagatc taaagtcagt
    16681 actcgagttg cccctgcttc ttcgatcaag ttagcgatca atttcgcagt gatcggttca
    16741 tgaggtttcg ccgtgcggtc ttgcctagca tacccatagt aaggcaatac gacattgatc
    16801 gttttcgcac ttgctcgctt cattgcatcg atcatgatca gtagttccat atagtaatca
    16861 ttgacaggtg cattcgttga ttgaacgata tacacatgat cccctcgaat actttcttcg
    16921 atattgatgg aaatctcgcc atcactaaat tgcttcacga cgcttttacc taattctgtt
    16981 ccgaacactt tcgcgatttt ttcagctaat ggacggttgc cattcaaact aaaaatcttc
    17041 aacgtgtcat cctgatactt attactcatg tagtcctccc caaaacttct ctattcttcg
    17101 atagtttaac atatttttcc aagattttct gttaatttca gcaaattctt aaggaagtga
    17161 aactgttccg ttactccaac tggcaggaat gactttatga taatcgcccc agttgtcgtg
    17221 tactttgtaa taacgttctc ctgtttcagt ttcaaaataa gcgtacgctg tcacccaatg
    17281 attgccatat gtactgccaa gtactttcaa aataccaatc atcacaggtt tgccttcacg
    17341 tatacgtttt gtagctcgct gccatgaacc tagaagagtt gctcgtgcac gctcatgatt
    17401 gccattcttc tttaaaaaac tagaaatccc tgtactaacc tgaaaaggaa tcgtaggaag
    17461 tcctagtggt tggatctggc tacgcaatgc cttcgtcaaa accaacgaat cagccgtatt
    17521 tttcttgcga atctcatttg gaagcatcca ccccttacga tagtcttgat aataggcaag
    17581 gagaactgct gccgcgtaag taccacaaag atagcctgag ggggtagccc atttcttata
    17641 cctcaaaaaa cgttcttctg gcaatcccac ccagcaattt gcgagttcct ttcctgacct
    17701 tttttcttcg atcaaaacgg gaatatcttc ttttctgttg atccatctag ataactcgat
    17761 tggctcttca ttgatcagct tccatttttt acaagaaaga ccctcttgat aagtatattt
    17821 tgctggagaa tattctaccg gatgtcctga ttgatcgata atcacataac tttgatcttc
    17881 aaaaaccaga gctaaaaaaa gcaatttact ttttcttgac tgcagctgct gagtgctggc
    17941 taatttttta atttttttat ctactttgaa atataaaggt ttatccacta cttgattcag
    18001 ttgggatcgc ctcctttttt tcattataag tgaaggattg aaaaaaacaa atcagtttga
    18061 ttgttcgaat tttcaatttt ttatgttcta tttgttaatt ccttcatttt gtaagataat
    18121 gggcacacga aacaaaaaag gagcgatcga tgaatgaaca aagaacgatt gaaacaagat
    18181 ttctatgaag cagtcaatga agaatggcaa aaaacagcaa aaatccctgc agataaacca
    18241 gctacaggcg gtttccaaga tttagttgac gggatcgacc aacttttgat gggagaaaca
    18301 gacgatctgc ttgcccatcc agaaaaagtg tcttcagaaa aaatgaaaca tttccttgca
    18361 tattatcaac tggcaaacga ttatgaccga agaaatgagt tgcatgctca accgcttcaa
    18421 cctataatcg aaaaagttga atcattgcag tctttcgacg aattgaataa gcaatttcca
    18481 gaatggctgt tggatacatt accattgcca tttaatctgg atgtagatgc agatatgaag
    18541 aatgcgcaaa cgaacgcctt ctttgcttat ccgccttctt tattccttcc agataagacg
    18601 tattatgcat cagaccatcc caacggtgca caactaatag gcgttttctt tgatatggct
    18661 gttcagttat tagagcttgc cggcaaagaa aaaagtcagg cagaagcaat cacggaacaa
    18721 gcagtgcaat ttgataaatt gattgctcct catgtaaaaa gtgcagaaga aaacgcagat
    18781 tacagcaaaa tgtataatcc gcaatctttt gatacattta ttaaatacac agataaactg
    18841 gacttgaaaa aacttgtcac gggtttgatt gggacaactc cagataaagt gatcgtaact
    18901 gatccagtgt acttcgatca tttgaatgac atcctgacag aagctcattt tccgttattc
    18961 aaaagctgga tgatcattaa aacagtacgt tctcttagtg gttatctatc agaagaattc
    19021 cgccaagtca gcggaatcta ttctcgcgta ttgtctggaa cagacgaagc aatgcctcag
    19081 aaaaaagcag cgtattacct tgcctctgga caattcgatc aagtagttgg cgattactac
    19141 ggaaaaaaat attttggcga agctgctaaa aaagacgtag aacaaatggt gaaaaaaatg
    19201 atcgccgttt ataaaaaacg tctagaagaa aatgactggc ttggggatgc aacaaaagaa
    19261 aaagccgtca taaaattaaa taacttaggt atccaagtag gctaccccga taagatccca
    19321 gcattattcg accagttcaa aacagtacct gcagatcagg gtggtacttt gctttcaaat
    19381 actcttgttt tcagcaaact cacattaaaa gatcgtttca gcaaatggaa caaaccagtg
    19441 gatcgttcag aatgggaaat gagtgctgac acggtcaatg cttattatca tccatttcgg
    19501 aatgtgatcg tctttccggc agcgatcctt caagcaccat tttacagtct agaacaatca
    19561 agctctgcta attatggtgg aatcggagct gttatcgctc atgagatttc ccatgcattt
    19621 gataataacg gcgctttatt tgacgaatat ggcaacttga acaactggtg gacagaagaa
    19681 gatcttacac aatttcaaaa caaagcacaa gcaatgatcg aagaattcga tggtctgcct
    19741 tttgctgacg gaaaagtaaa cggaaaatta accgtttcgg aaaatattgc tgatgcaggc
    19801 ggtctaagct gtgcattgga agcagcaaaa acggaatcag atctttctat cgaggaattc
    19861 tttgtcaatt gggcaacgat ttggcgtaca aaagcaaaaa aagaatacca acaactttta
    19921 ctgcaaatcg atgtccatgc ccctgctaaa ctccgagcaa acgtgcaacc aaaaaacctt
    19981 gacgaattct atgaaacatt tggtatcacg gaacaagacg ctatgtatct agcgccagaa
    20041 aaaagagtgc gaatctggta agaggttgtg ccagaagtgg tcagcttcaa gaaataagaa
    20101 ggaatttggg aaaatcgctt ctcaaatttt tgtgacattt cggcttattt ttcgaagaag
    20161 ttacttctgg aataccatgt attagaggtt gtgaaaaagc tgcttagttt caagtagtaa
    20221 gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttgactta ctaccgagaa
    20281 actggctttt gaacaccgtt tatcgagagg ttgtgaaatc agcgtcctga cctgagtatt
    20341 agagaaaaaa acggaaaaat agttcctcat attttgccgt ttgttgagct aataccgagg
    20401 gtcagctgat tgaacaccgt ttagtggaga gattgtgaaa aagctgtcct gcatcaagta
    20461 ataagaacag ccaatcaaaa gcagcaagga gaacctcatc tataaaaaga tagaaggaag
    20521 tgagacatct attggtctca tttccttcta tttttacttt cctcagtcaa ttgttttaca
    20581 tcataaaagg agaaattcca cttatttttt tcgctgtttc atgacataaa caactacacc
    20641 gattaacaaa attcctccag ctaatgctag caacgggtta ttaaattctc ccgtttttgg
    20701 gagtccttga gtgccatttt tttcactttc ttttgctgtc ctatccggat gagaaggttt
    20761 tccatttggt tttccatttg gtgattcatt tcctggattt tctctttctg gtttgtcatt
    20821 tcccgggggc acatcggcag tttctcgcac agtgatcgct ttttgctggg taacagattc
    20881 tgtatgagca gaccattttt ccccatcaaa tatttccgaa cgataagtga cttctagcgt
    20941 atattctcct tttgaaggtg ctgaaaaaat agcggtatga ttagaaaatt gagcacttga
    21001 ctgtgtttca acgatttgga tcttttctgg gaaataacgc atatcttcaa agacaggcgt
    21061 tccttgattt ggtgtgaaag ttgacacaaa aactgtaaaa ggcttcagtt caatgatatt
    21121 tccttctgca ttctccgcca caccatttgc ttcttgtata ataatcggat tattttgttc
    21181 atttggtttt gtctgatttg gttcttgtac gattgcatac tctggatatt ccgaagacgg
    21241 tgaggtttct ccgtcaaaaa tagcacctac agataatgga agaccatcca ctctttcctt
    21301 ttctgtttga cgattccccg gtttaatctg catcagtcca tgaacatgga tacttccatt
    21361 ttcatagcgc gtaacaggct gctgaccttc tttcgaacat gtatttagag actcgatcca
    21421 atcttttgat atggtatgtc caagagtatt ttctgattgt ttctctcgtt cattccaata
    21481 gtagttcaac gagtggtaga tttgatcttc gttttgattc aatgggcgga tctgctctct
    21541 catctcaaga ttctctgttc ggaaagataa gataccagaa gcatggtagt ctgtgtttcc
    21601 tgctgaagag gtataaagag ccacattata tgaaccgtta ttaaaacttg tactgctatt
    21661 gacgataata tctgttccgc tattggaatc gattcctttc gcaagatttt cgaaagacaa
    21721 actattgatc aattcatgag ggcccgttaa agaagaaccg cccattttga atccattacc
    21781 gttaccttct ccctcaattc ctggtaccca gccgtttcga taagcaactg agtttttgat
    21841 gattactttt ccgatcgaac ctgtttcatt tttagcaaaa aggtcccaac cgtcatctgc
    21901 attatgatac gcgatacaac cgtcaaatac atttccttct cctattgtca gtttggccgc
    21961 aaatccatcg gcatcttcaa atcctggatc ggcattttca aaagatgtac agttcttgac
    22021 taagttatgc gcgggccatg cttcgaaagg atcatttgag ctaccgctga tttggattcc
    22081 tgtatttcca ttccgataag catgaatctc ttcgatcaaa ttatgatttc cagaaatctg
    22141 taatcctttt tgcatagctg cactatttgt aatgtcaaac cctcgtaaac cccagtagtg
    22201 actgaacagt gtcatcccat ttccagttcc tttaaaatca agtacaggac gcttgttttc
    22261 tggatttttc tctgcaatca actgaatcgg gttttctctt gtcccgttaa cgccttttgg
    22321 aatcgtcaat cctctttcga aggaataagt tccaggcgcc atgacgattg tctgcccagc
    22381 atatgcgtat ctcaatgctt gtgtcagaga taatggattt tgtctgcttc cgtttcctgc
    22441 atctgaccct tctggtgtta cataaactgt cgaatattta ggtttacggt agtccactgt
    22501 atgaagaatc tcttttgttt cataactagt catctctacg tattcttctg gcggatagtt
    22561 tttatctggc gtaaaactga aagtaaattc gttcgttcct tccatcagtt ttgtctgata
    22621 atcaaattcc cgattcgcag tgatagccaa gttttttgcg ttcttaagca cctctcctgt
    22681 tgctttattt ttaattgtca ataatccgtc agcatttgct ctaaaggaca tagtatgatc
    22741 ttggtttcct gaatgattac tagaggtcac agtgtaaatc ggatcaatca agcgagtagg
    22801 tctttcttgc ccaggaggat ctgtcgcagg atctgagtaa gcaacttcga ttccttctac
    22861 cttgatcgtc atattccttg ctgcagcaaa tcctgcataa ataaccgatt catctgaagc
    22921 gtataatttt tcccagtcat acatgatgtc agaagccatt tcttctcctg tttcaggatc
    22981 gtaataatat gcctctaaac cagtattcgt ttttttcatc tctacgtcca gtttagtaat
    23041 cgagttcgtg gccggaaaca gattcccatg accgtttccg aatatattat aagaacctgt
    23101 ttctttttcc aagaaccctg ctgaagtctc taaaggtgtt gtttccactg agacactccc
    23161 aggagctggc gcagcttgcg gatcttcaga tgatattcct gtgattgccc gtgtccccaa
    23221 tccaagtcgc atcgtatatt tgctgccgct cgtgttgacc acttcttgtc tatccgagtc
    23281 ccagacatat tcgatccgac tgcctagtat ggcaaatgaa tttgaataaa atgcctgccc
    23341 aaacaaatga ttttttggta ctgcgtctct taccattaaa gcaaatcctt cttgggcatt
    23401 cgtataggtc caagattcta tttcgatcgt cgcccgcatc ctaaagttga tgtctttggg
    23461 gattgcttga taataatagg tcattccatc tgatccgctt gactggaatt ttccgccgtt
    23521 attcgtggaa gagagccgca cgccgtcttc taatggttca atggcatacc tactagcact
    23581 tgtgctttct ccgaaaacaa cccctttcca ctcttcattt gcttcttcag attgcttttt
    23641 tgtcttttca ttttctgatt ctttcatcat aggatcattt ccttcttccg tatccatatc
    23701 ttcactagtt cttggtattt cctccattgt tgacatccct tcaatgttca cgtgtgcatt
    23761 ttcttcgttc acagactgtt gttcgttagc agcaacttca acgacagaaa ttaaaaccgg
    23821 ggtactgagc ataaggagat tcatcattag cgcactgtat tttatacgtt tttttaacaa
    23881 gtgtattcct cccgtaacaa attagaaagc gtttacttaa agtattacct aatttatttt
    23941 tactgtcaat aaaaaacaaa attataataa gtgtatttta taaaaagaaa aaatataact
    24001 taagttgttg ataataaaga gatttattaa cggaaaaaga ataagttttt ttaaaataac
    24061 gtataaaaaa gagcataaaa caaagtcgtt tgttttatgc tcttctttta ttattttgtg
    24121 ctttttattt tatcaaatca ctttgttttt ttataaaatt tctgcgccta gtgtggactc
    24181 aaaatgtctc aatgcccatt catgtccaac gggatcgaaa cttgccacgg aatctttgaa
    24241 aatatggagt ttgtatccta gattatacgc atcgactgct gtatgcaaca cacagatatc
    24301 tgtacatacg ccggtcaaat aaatatctgt gatctggcgt tctcgcaaac ggatgtctag
    24361 atctgttcca ctaaaagcgg aataatgccg tttgtctatc caataaacat tttcctcttg
    24421 ctcatagtct tggtataaac tttttaaaga gccgtacaat tcccgtccac ccgttcctat
    24481 cacattatgc ggaggaaata agcggttctc cggatgaaag gaatcttttg gatcatgcgc
    24541 atcaatggca aaaacgacaa aatccttttg atcaataaac ttctttgtat gagcagtcag
    24601 ctttttttca attacttgtc ctgctgtccc agtagtcagc tttccatcct ctgcaacaaa
    24661 atcatatgtg tagtcaatcg agatcaatgc gttcatctta gtcctcctta tacgagatgt
    24721 ttgacaaatt cgatcaccat ttctgctgat cgtttgcctg cgtcttcgat aaattcgtca
    24781 aagctttgtg tcgccgagtg atctgctgtg tcgctcattg cacgtacgat caaaaatggg
    24841 atattgaact gacgagctgt ttgtccaaca gcggctcctt ccatttcgca agctaatgct
    24901 tcagggaaat tcgttaagat ttctttgatt ttatctggcg agtcgacaaa tgtatcacct
    24961 gtaacgatca atccttcttt tgcgttcaaa ttcgttgctt ttgctgcttt aaccatttca
    25021 ctgcgcaaat atgtgcttgc ttcataatat agaggcattc ctggtaattg tcctgggttg
    25081 tagccaaatc ctgttgcatc tgcatcaaaa taagctactt tgtctgatat aacgatgtca
    25141 cctacttgta agccttcacc gattccgcca gctgaacctg tattgatcac catgttcacg
    25201 ccgtattgtt ggatcaacag acttgtggta atagatgcta agacttttcc tataccggaa
    25261 cgtacgacga tcacttcgtg gttacctaat gaacctgaaa taaataaagc gcctgcgcgt
    25321 tcccatgata atggttcgct taggttctct ctcaaaattt ttacttcttc ttccattgcg
    25381 ccgataatac cgattttcat ctttttaatt ccttctttct atataaatgc gattgctaaa
    25441 aaaaccacac ataacattag gataacaata ataagagatt tcatcaaaaa agagttccat
    25501 ttggtcgtct tttcccgttc gctgatcctt gttttcgtga ttggtttatt ctttttgctt
    25561 tctttacgat aaaagctggc aatctttttt tcttcttgct gataagctgt ttctgctttt
    25621 cgctgttttt ttaatgactc gcttgcttgt gcttgttgtc gcttgcgaag ttcgcttcgc
    25681 gtaataagcg gtcctttggc cataagccga tccctctact ttcctttggt caatagttcc
    25741 cagtattgaa tcgcataaat cgtctttgca tcacaaatca actgatcttt catcgcttgt
    25801 tgcgcctctt caagagttag atgatacaac tccagtactt cgtcttcatc ttgtgctaaa
    25861 ggattctcga ccttctctac cccttgtgca tgataaatat gaaggacttc atttgcaaaa
    25921 cctggtgaaa gatacatcga agtaagatgg ctcagcgact tcgcacgata gccagtttct
    25981 tcttctaatt ctctagctgc tgtcatttcg ggattttgtc cttctcctgg atcgattttt
    26041 ccagctggaa tctccaaaat cactttttct aaaggttttc gaaattgttt gacaagaagc
    26101 agacgatctt gttcgtcaaa agcaatgatc ccgacaccgc caggatgaaa taccagttct
    26161 ctcttcgaag ttcctccatc tggcaaacga acttcgtcta cagcaacatc aataattttt
    26221 ccgctataga tttctttgcg actgattgtt ttttcttcaa attgctcatt gttcagcata
    26281 tcttctcctg ctttctttgt aatcataact gctttttttt catttttcaa tttttctcaa
    26341 aaactcctta ttagtttacc atagataaac cttagatttt ctctaaatat agaaaatcct
    26401 tctttagtcc gatactcttt ctagtagtcc gtatgctaaa ataagtatgt aatcgaataa
    26461 cgaaaagaat tcaatactca acgataaatg acatggaggg tttattatga taaaacgaaa
    26521 ttggccgtgg cttctagcat tggtcttgct atttctcttt gtccgaaaca atagtttttc
    26581 ttttgttcta ggacttttat tgataggtgt agttttagtt ttgtggggac tctttggttc
    26641 gcgcaggaaa aagggaaaac aagaagaaat tcctgcactg actgacgaac ttgaaactca
    26701 ctatgaaaaa agcggtatga cagcgaatga aatttcattt tttcgacaaa caatgaatca
    26761 aacaaaaaat gagatcaatc aattgcaaat gaatatgcag cagacagcca aacttaaagc
    26821 aatcgatctc cgccatgatc cagtcaaagc agcgaaagct ttattcaaag aattggtgaa
    26881 agaaccaaac cgactgcatg aagcaagtca gtttctttat acgcatctgc cgaatctagt
    26941 tgatttgaca aataagtata atgagatcaa tgaccatgag atcaaaaaca aacagaccta
    27001 tgaaaaacta gaagaaagcg cgcagatcat cgaccagctg tcagctttaa tcgcacaaga
    27061 ttatcaaaaa ttcgttgctg aggatctaga tgatatcgac gtagagatat ctgttgcgaa
    27121 acagagctta aagcgtgata ataaatatga accagaacaa aaggattaac tcttttgttc
    27181 ataaaagaag actcggaaca ttcagatgat gtctggctgt ttcgagtact ttttctaaag
    27241 tagagacatt catgtaagaa tcgagaacag attcaacaag gaggaatttt ttatggatca
    27301 taaaccgact gaaacaaaag atgttacacc agttaacgat acacttgaag atttattgaa
    27361 caacccgttt tcaactccaa cagatacgct gaccacttca caacaagcgg agattgatca
    27421 gctccaagag caacagacag ctgctcgttt aattgacaaa ctaccggcgg aacgccaaga
    27481 acaagctaaa cagctagcag caaaaatcga tgctaatgat gcacagtctg tcatcagcta
    27541 cggatcggct gcccaagcaa aattaagtga attctcacaa tcgatgttga atcatgtgca
    27601 agcacaagat attggtcctg taggagattc cttaactgaa ctgatgtatc gtctccaaga
    27661 agccaatcct gacgaactgc gtgccggaga agggaacatc ttccagcgtg tcttcgggaa
    27721 ggtcaaacaa tcgatctatg aagtgacagc aaaatatcaa aagattggtg cacaaattga
    27781 caagatttca gtgaaattag ataaagaaaa agacggtctg ctaaaagata atctgatgtt
    27841 agaacagctt taccagaaaa acaaagacta ctttgatgca ctgaatattt atatcgctgc
    27901 tggagaattg aaaatggaag aacttcaaac aacgatcatt ccagaagcga tgaaaagagc
    27961 agaagaaact ggcgatcaga tggatgttca gattgccaat gattacacgc aattcctaga
    28021 tcgtctggat aaacgtacgc atgatcttcg cttagctaga cagatcacga tccagcaagc
    28081 accacaaatc cgtttgatcc aaaacacaaa tcaggccttg gctgaaaaga tccaagcatc
    28141 tatcgctaca gccattccgc tgtggaaaaa ccaagtcgtg atcgcattga ccttgcttcg
    28201 tcaaaaagat gcagtaactg ctcaacgcca agtctctgaa acaacaaacg acttattgaa
    28261 gaaaaattca gaaatgctga aaatctcagc catcgaaaca gcgaaagaaa atgaacgtgg
    28321 aatcgtggat atcgagaccc ttcaaaccac tcaaaatgat ttgatcgaaa caatccaaga
    28381 gacattgcgt atccaaaaag aaggaaaaga aaaacgtcgt catgcagaag tagagcttgg
    28441 acacatggaa gaagatctga aacaaaaact gttggattta acccaataga tcacctttcg
    28501 cttgttacta aaacaaacgc ccaacaacag tttattacaa ctgttgatgg gcgtttttct
    28561 tatctttctt ctaacttctc cattggagtc tatttctcat tcatcttgct gtgtccatag
    28621 ccatagccaa aataaatgat cagtccaata accattacga taccgaacac gatccatgtc
    28681 acagtttgca gacgaagcat caatacaata caagtcaaga tggagacgat tggcaatagc
    28741 ggaacgaatg gcactttgaa ttctccagct tttggtttgc caaacatttt tctcaacttc
    28801 agtaagccta gactaacaag catcaaatag gcgagcgcca tgatattcgt tagttccgct
    28861 aatacattca atgggaaaaa tccggcaaag aatacagctg ccacaccagc ggcataagtc
    28921 gcttttttcg gtgtacgatg cttttgatcg atttctgtca taaacttagg aagtaagcca
    28981 tccttgctga cagcaaacag taaacgagca agtgaataca tcatcgagat cgttaccgtc
    29041 agtagcgtta aaattgcccc tacagcgatc accgcgccca ctgttccatg tcctacatac
    29101 ctcattgcaa aagccactgg gtcattgact cctagttcag tatacggaac gattcctgtc
    29161 aagatcagcg tcacgatgat gtaaaggaca gtagcaatca gtatcgaacc aatgattcct
    29221 cttggcacat ctttttgcgg gtttttgact tcctcggctg ccattgcaac ggcatcaaat
    29281 cccaagaaag caaaaaacac aagagctgca ccatctagca caccggaaaa accaaaaggc
    29341 atgaatggct gccagttatc aggtttaacg aaaaatattc ctacaatgat aaacaacgcg
    29401 atgataccaa atttgacata taccatggca ttattcaaac gtaatgcttt cttggcttca
    29461 agcgacacga tgtaagtgac gaatatcact acgagcaccg caatcaagtc aatgtatgta
    29521 ccattttccg gattgtaccc gccagttaat gcttgtggaa gttcggcccc taaacttttc
    29581 aaaaaacctt gcatatagcc agaccatccg gaagcaacag aggaaaccgc tagtaaaaat
    29641 tccccgatca acaaccaccc tgtcagccag gcagcaaatt caccaaatac aacatacaga
    29701 taggcatatg gcccaccaat cactggcact cgcgaagcaa attctgcgaa acttagtcca
    29761 gacaaaatga caacgattgc agctaagaca aatgaaagtg acagtgctgg accagcattt
    29821 tgattggccg caacccctgt caccacaaat attcccgtac cgatgatcgc accaattcca
    29881 agcatgatca aatcagacgt ttttagttct tttttcatct cactcgtatg attgagattg
    29941 atctctttct tacgaaacaa atccattgaa gttcctcccc attttaggtt ggaaaacagc
    30001 gattaaactg ttttcatata ccctaaaagg ataccaccta aaatgactaa aaggcaacca
    30061 acaataacat aaatgagctc ttttttcgtt tttctttcgc caaggatgaa aatcccacct
    30121 aaagtagaga taatgatccc catttgtgaa agtgagaagc caacagctaa accaagtgat
    30181 ttgactgtta gaagcatgca gatgtttcct aagccccata ataatccaca gatcatgttt
    30241 ttccacacaa actgatcgac tttaacttta cggaaagcaa agaagcttgc gcctaagatc
    30301 attccgatac tttgaggtaa gataattgac atcgcatcca aattcgccca gttgacgatg
    30361 atggtatata caccataacc aatcgtagag aagatcaatg ctctaaaacc cttaccaaaa
    30421 tcaagcattt tattatctgt atctattttt ccttcgtcat cttgtcgggc agtcaaatac
    30481 gcaccgctta caagaagagc taaagcaata ataccgtata cataatcttt cgtttgtgtc
    30541 cattcatgga agaaaacggc tcccgcaatc gtattcaaaa ttaattgaaa accagtagac
    30601 aatggtagcc ctacagaaac acccatgtac ttcattccat ggaactgtcc attttgtcca
    30661 acactccaag ctaagccgga taaaaatccg atcaagaaaa tccaaggggt gattacagga
    30721 ctaacaacga aaaagacaac taaagaaaac agaaatgcac cgatcgtcat tcctagtgtt
    30781 tgttgattgg catcgccacc aattttacca cttactaaac caatactacc ccatgccaac
    30841 atagggacta atgctattaa aatttccata accaatctcc ttttatttca catgataaga
    30901 aacttatcag cgaaaacgtt aacaacacaa gcactttttt tcgtttctaa cgattttcta
    30961 acgtttttca ttataaaaat ttaagattgg gaaaaataaa gtcattgttg tcccttttcc
    31021 ttcagttgat tcagccgtca aatggatacc taatttttcg gccagatttt ttgctaaata
    31081 aagtcctaat cctgttgaat gtgttttgct aagtcgacca tttctcccag taaatccctt
    31141 atcaaagatc cgtttcaagt cttccgctgg gataccgatc cctgaatctt taactgaaag
    31201 gctgactcct tgcgcttcct tttctatgct cacaatgatg tttccgtgat ccggcgtata
    31261 tttgatggca ttactaagca attggttgaa gataaaagcg atccatttag catcggtcaa
    31321 aacagtatga tcctcaccaa cgatctcgta gcgaatattt ttttggataa aataatttgc
    31381 ctgactgcgt atcacaggct gaatgattcc ttttagtcca tattcttgga tgaggtagtc
    31441 ccgcgagaaa ctgtcgagtc ttgcataata caaaacttgt tctacgtatt catcgatttt
    31501 tgataattca ttttctagta atgtatactt ttgatcgtca atatcgaact cgatcgaacg
    31561 aactagcaat ttagaagcgg aaagtggcac tttgatttca tggacccatg agtcaatata
    31621 atctttttgg tcttgttgat tactgattgc tgattgcatt acttcttggt gttcacggat
    31681 cagctgattg atatattctt ctaccagttt ttcttcttct gtcctcccac cactcaaata
    31741 attttgcaaa ggggaagttt tttgtatgtc ggctaatttt ccccaccatc ttctcttgct
    31801 caagtaacca cccagcagat aaaaaatcag aaagacgccc tcaatcaaag ctaaataagc
    31861 aattgtgctc aaatcaactt tgatgtttgg cgccagccac atcacaaaga tcgtcaatgc
    31921 aataaaaaac agccatccca agatcaatgt ccactgatct ttcaaatatt taaaaaaatt
    31981 catcttaacc gctcatcctt tcagggaacg atatatccct gtcctacttt tgtttcgata
    32041 tatccttgga tacctgcctg ttcgattttt cggcgtaacc gattgatgtt gactgtcaat
    32101 gtattgtcat ctacaaatcg ttcgtcatcc cacagtgctc gcagcaattt ttcccgactt
    32161 aagatctttc cattgtgctt catcaaaata aataatagac gatattcatt tttgctcaaa
    32221 tcaatgatct ctccgttgat ttccatactt ccgttgtcaa cattcaacgt aatgccattg
    32281 tggctcatca tttcactaga taattctgtg tagttgtaag aacggcgaag taatgcattg
    32341 atttttgcaa tcagtacatc gatttggaaa tgttttgtca caaaatcatc tgcccccatg
    32401 ttcatagcca tgatcatatc catattcgta ttcctgctgg agataaaaat gatcggtact
    32461 ttcgatactt cacgtatttt ttgacaccaa taatagccat ccaaaacggg aagattaata
    32521 tctagtaata caagctgtgg ttcttctctt tcaaagtctg agaacacttg attgaaatcg
    32581 gtcgttccaa aggtttcaaa ttgccatttc tcaagttcct ccatgatcaa ttgtcgaatg
    32641 atctcttcgt cttcgactac catgattttt gccataaaaa atccctccat ctttcttctt
    32701 gctactacaa tatcaaagaa gcccttgtga aacaagttgg cttacctgga aaatgtcatt
    32761 ttagcaaacg ttaaaaaaaa ctggaaatat gcgatttaat cgcgtttgtc tcttccaagc
    32821 agcttaaatt tattatgtta ttcttaataa ttggtctatt atctgttatt tttctttcgt
    32881 tgtttttgtc ttttaaattt tcgataacac caataaccga aaagcgttag cactagcaat
    32941 atacctagaa ggagtataag taatcgataa agatggtatt tttttgtctg ttctatcttt
    33001 gaagagactt cttctgtaaa gggaactcgt cttcctgtca ctagtaatcg gtgagtgttc
    33061 acggtgtaag gtgtacaagt gataagtgtg actagatcct gcttttctct aattgctaat
    33121 gtatttgttt ttgttggaag gacaacaatt ttctcaacga cttcataagc gagcatccga
    33181 ccatacactt caagatagaa tcggtcatct tgctccattt cttcaagatc cgtaaagagt
    33241 tttttctcag caataccgct atgggcggta atcacggaat gtgtactctc tcctccagtt
    33301 ggaaaagagg tgccttgcag gactgtcgct cctctatcta acaaaagatc attcgtttca
    33361 tcaaataaag gcaagctaac attgattttc ggaatataga tggctccgat catatgttgt
    33421 tcgtaatatt cttttcctgg attttggaca tttctaaccg cttgctcaaa aggatctttg
    33481 acttgtccca ttcctgggat tactgatgta tgagcaagcg tctgattttt cttttcatgc
    33541 actgctaatt gttgctcatg tttttcttct ttatcgcgtt caagctgctt ttgataattc
    33601 tcgatccttc tttgatccaa ataattgctg agagcatctg ctaaaaatgg atatgtaaaa
    33661 actgcagctc cggcaagaaa catcactgcc ataaataatt gtaataaaag actgatttgg
    33721 gtttgaggtc tattacctat tttctttttc attttcttca ccttcttatt taaaaaaact
    33781 gcagcaacct ttataaaacc gattgctgca gcttattttt gttgcttata cttcagactt
    33841 cattttagat ttacggtacc agctgtacgc tccaatcatc aaacttattc cgattagtaa
    33901 gaatgccaag agcccgttcc caccagtagc aggaagtgac ccgcgtttca tattcggtac
    33961 tctttctggc cctggatttt ctactcctac gatctgaatt tcttcattat agcttccata
    34021 agagatgata aattcagtaa aggctgcctc acctgttgga agtacataac cttctggcgc
    34081 catggtctct ttcatttgat aggttccata atctaaccct tgaacctcaa agtatccatt
    34141 tccatctgcg acaaattctg ttgcttgtcc gcttgttgcc cactcaattc tatctgctcc
    34201 tgattcataa acagctaaag gcgactcccc tttataaaat attgcgtatt cagaacggtc
    34261 ttcattccac aattcgaatc ttgcatcttt aagcaattca ctgcttgatg catcatattt
    34321 ttcaaacttt cttccacctg ttgtgacttt ctctggcggc tctactcctt cttcataatc
    34381 aaattcatca tttcgtccga tttcaataac cgctgtgttg ttatggaaat catccgcttc
    34441 tagttctgtg gaaaccttca aattatacgt gatcgttaaa tctcctccac gtgcatctgc
    34501 taatctacct aaagtatcta ctttggctac tccattttct tctgtcaaaa tcgtcacgac
    34561 aaacccgttg cttactactt ctactatata atcttgtcct tttgttaaaa tcgtctcgcc
    34621 ggctcgcact tctatttcct gatcataata agttagacca actgtaggcg tatctgtgat
    34681 tttgtaattt ttgataacag cgcttccgtt ttcaaggaca gaatcgatga aataaggaat
    34741 aggtgctgtg atcgtgtaag aagccgtttt tcctctttct agatcaatat aagaaatcgt
    34801 ttcttgttct ccagcttcat taataatcgt tacttgtcta aggtcgcttt cctctacatt
    34861 catctgttta tctgcttctc tgatttcgtt tttcggatac aaatgcacat ctgtattgta
    34921 tgtgtctttc catgtagaac catcccacac gccatccacc atatcaggca tcatcactgg
    34981 catcataaca accattggag acgcgattct ggaaatatga gctggcgaat aagtttctaa
    35041 gaaaagatag actttatctc tagaagaagg tgcttcttcc gtcacttgga cggtagagaa
    35101 taccgcttct ccagcttcat tcgttgtttg tttgtcaata cttgtcagtc gatattttaa
    35161 aaaccaactt tctgtgtgcc gtttttgaat ccattcaatc gcttcggcag aattaagacc
    35221 gtcttctcgt tccggtgtta aaggattatc tcgaatcaaa tcgtaatata cttccgttac
    35281 gtcaaacaaa tcaaaatcga ctcctggaat attttcttca ccaaaatccg tagaaaccaa
    35341 tccgctattc ggtcgttctt ccggaacaga tgagaaacct tttttgtgta atgtaatcgt
    35401 cacttcactt ggtttttgtg cgacttcttc ggctttgact agttttccgt tcccgaaaat
    35461 ccctattccc gcagtaacga gtaacagtac actcattccc gtgacaatca tttttttatt
    35521 catttttttc tccccgttct ttttttatta ataaaacagc acctaacaat aaaagaattc
    35581 ctagtaaaga aatcaacgtt cttgcttcat tcgtttgcgg gaatacggac cattttcctg
    35641 attgacctgg attgcttgga ccactcggct ctttcggttt gtccgttgtt tcttttacgg
    35701 tctcgttata aacacgtggt gttgcggatt cataggcaga gactggaact ttcccggatt
    35761 ctaattcagc catctcctgt ccgttaacta ctacatattg tggttggcct tttgcatcca
    35821 cccaaaattc agggatgatg acctcgattc tcttacttgc ttcatccatc tcgtaacctt
    35881 ccacaccttt taattcttca aaataatagg tgccagaagg caagaaacgt tgtcctgtcg
    35941 taacaaggcc ctctttatcc gaaatgaatt tgcttacatt tttgtcattc aaaggatcat
    36001 tgtctgctgg tttgatccat tgatttttca agtcattagc aggagccata tctaaataat
    36061 atttcccccc ttctatcatc tgatatagag caaaaacagc accttctaat ggttttcctt
    36121 tttcagttgt tcctctttga cgtccatact tgaagaagta tggatctctt agataaccga
    36181 catttttagg atagatatga atctcttgca gttcctcggt tgattctgtc gggtgataaa
    36241 ttggcaaaat agcagcaatt gggatagctg tctgatcgat atcaacatcc aatccaactt
    36301 ctggatcaat cgattcttcg aaaatcaaat aaactgcatc ccgatcttgg tttttcttag
    36361 gtgctttgat acgtgcaatc ccgtctccta atccgccaac cgtatctttc ccagttgtta
    36421 ccgaagtccc tatttggaca agcctttctt ctgtgattag ctgacggata ttgtttctgt
    36481 tcgtttcagc gatttgctgg acgaattctt taggagtcat gttttcagca gctttttttt
    36541 catgataata atcggtcatg tcgtaaatgg caaatgtcgc tccatttagt ggcaccgtct
    36601 gtgaaatgat atctgctgtt tcccctgctt cctcagagat agccaagcca tcattttcat
    36661 ggtattcaaa ttgatcgtta taatcgatat ctcgaatcat ccgtttatgc aacacgaatt
    36721 ccacgacatc ttcccctgat tcttctgccg acatcgcatg tggaagaagg actgctgcaa
    36781 gcggtagtaa aacaagtaat tgaagcatca aacacaacag ctttttcatt accttgctcc
    36841 ctccttttta gattgtctga caaacaaacc ataggctgct cctgcaagcg ccatgaagaa
    36901 tgcagcaagc aggatataga ataatcgtcc ggatcctcct gtagcaggca acggattttc
    36961 aggatcgttc ccgacactaa gctgtaatct gattcgattt gtctccaaaa gttcatattc
    37021 taactcttgc tgtagatcag gcgtctctgc ttcttcgttt ggataatacg aaatctcaac
    37081 ttttagtgta cccgcttctt ttcctggaac tacccgatca ttttctatgt caggttcttc
    37141 tcgataacta atttctaaaa taaagtaacc tggaagtttt ctatagctgt caggtgactt
    37201 cacttccttg atccgataga ccccttccaa caagtctgaa gcattgaata gggaagaatc
    37261 gtttggatct ggtgccaagc ctccctcgat gatttcatac tctcctgcac tattttgttt
    37321 ctcaattgaa aattctgcgc cttcaagacg tcggctattc atactgtcaa ttttcaaaag
    37381 ttccaaatcg attggcgcta gttcatcttc taaggttact tgtagtacac catcgatgat
    37441 ttcatagcct tccggcaagg gagcagtttc gtcttcgatg accgtatctt caatgataaa
    37501 cttaccttct tcattcagtg caaactggaa cacttgatca gatagccgat acccatttgg
    37561 tgcgacagat tccgagacct catattcacc aatagacaga tgcagaggtt ggtcgtaatt
    37621 taaatcgaca tacttttcta ctcctacggc acgagaatag aagtatccga tcccaggcaa
    37681 acgtttcgat tcttctggtt ctaacggatt accagtgtat gctcgataca gcgggaagga
    37741 agaatccccc actttcctga tatcgaaacc tgcaccatct aatgtatggc cttcatggtc
    37801 taattttcta actcggatct cccgataatc aaacgtattg taagcagtga atgctaccca
    37861 taaacgatcc tcttcatctg ttgtatacgt gagatattgc caattttctt cacctgtttg
    37921 cttgagttgg atagtcccta tagcattatc gtaaagtcgc aagatccatg tgtcattttc
    37981 atcaggttct ttgaaacctt ctgggttctg gctctcaatg attttgtatt ctgcatagtt
    38041 ggtagtttct tcactatcct tataaacaaa tgaatctggc tctccgattg gatgaataac
    38101 tttctcacca tccacgatta catatttccc gtcttcatct actgaataga acgtgagtct
    38161 ccctttctct tcctctactt cgttcacacc agaaagccct ttcgctactg gatatccgat
    38221 ttccagtccg ttaccatctg tttcataaag ttcaaactct gcgccattga ttggcatatt
    38281 actgccttca attagtttat tgatattcat gtggattggc ttgaattcat ttcgcatttc
    38341 cagtttgaca tacaactcat catactctgt gccttctatg ttaggctctt gtacaacaga
    38401 aagcttgtga tattctcctt cataatagga attcggatct ttaccttccg gtccgccgac
    38461 tctcgaacca gatgtatatt catctacaag ctcgtagtga cctaacatct catcttcgtt
    38521 ggctgcatat tttttgattt ggaattgata cgtctcatct actaactgat aacgtggtgg
    38581 tccagcgatc tctctgatcc aaaatatgtc gctgactgct ccagtttcat ctcctaaaat
    38641 cggcatcttc gtttcaaaga tcgctattcc gtccgtggta gttttacttg tttcgattgg
    38701 ttcggcttcc ccactctctg gattttggtc atataatgca aattcgactc cagccaacgg
    38761 ctcgccattt tgacccttct tgctgacttg gaaattacgg cctttatgtt cgtaacgaat
    38821 ggaagaagat gggaaataca tccgtccagt agtgatatca ttctcataat cctccaggtt
    38881 ctgaatatag gccatattgt tcactgtgca aaaatttccg tcttgagctc ccgcatcaag
    38941 ttttacttgg tacttgatcc tgaccatttc cccttcacct aaagaaatcg gagaaaattt
    39001 ataagcttgg ttttcccgtc cgacatacgt tgtcggagtc gccactactt ctggtggggc
    39061 ttgtccatga cgttcttcat cccatatttc tggctcttgg tacttcatgc cgttttctcc
    39121 tggatctaga tggtaaaact gaatatctgc cgatctgcca gctccaaatg gtgagacatt
    39181 aaaaccagtt tcatcataaa gtgtggcttg ctggatcgtt ctcttgaagg tagaagagat
    39241 atcctccaag gctgtaacaa tgtcattctt gttgttcgca ttgtaatatc gcggtgttac
    39301 gccatcttct tctaaatcag caatattttt caatacattt cgtccaatag catctagtcg
    39361 ttgtctcccg ctaacgtttc catcgattcc taaaccaatg gagaagatac ttggcgggtt
    39421 ctcttgatac ttgtttttca gccaatgatg ataagcaact gtgttgatcg cagatgactt
    39481 ttcttgcgaa gtaggactgc cattcgtatt gttattagaa gaaccatcac caacccagtg
    39541 agtcgcttta ttatctcctt cttttacctc tccataacga tagtgtacat ttacttcatc
    39601 ttctggacgg ttaaagtcag atgcataggt aactggatga gtaaaccctg cattagaagt
    39661 attcccagaa aactcctcaa aatttctgaa caaaacgtca ttatcttcag caatcttatc
    39721 ttccatcaca gtccagttgc tccaagctcc attagtgctc gtacgataac ttgactgaat
    39781 cggtgcataa ctgaaggtcg gtgtcccatc tcccacaacg attaggattt tttctggatt
    39841 tctattttct ccgccattgt ctttatacaa tgtttcatag ccatttttaa gccctagtgt
    39901 aagcggagtt cctccgattg gtgtacgatt taatgctgta ttctcacttc ccgtcaaacg
    39961 attgatatca tttgtcaatg gaaagatgtc cgaactgatt tgctcatggt tattgatagc
    40021 tgtactatta tggtaaaaat tcaccatacc gattcgaata tccagactcg ggtcagagag
    40081 cagatcttta ctcatttcgt ttactgcctc aatcaacgca gcatttttag tttgactatt
    40141 ggtcccagcg gttaattcac tcatactcgc tgacttatct agaacaaaaa cgatatcgat
    40201 tggactgatt tcctttttct cgcccccgat gacatctaga tagacattgt aaagggttgt
    40261 tgcatcttca ggatgtagat cagatgctgt gctgcttggc agaacaggtt ctacccattt
    40321 tttgatgtac gccccgttat aatccaagta actgttttca aaattccgtt catttcccca
    40381 aagctgaacg gtttgagctg gaacgtttct atcttcttcg cctgcagttg atccattatt
    40441 agtagcatag tcgtaatttc gccagttcgc tcccccgttt gtataatcac tatcatcgat
    40501 caagttctct ccgtcatatg gcgagccttt gtctccttga tagcgttcat tgctttgtgt
    40561 ccaatttcct aacacttttg tatagtcatt cgttgtaaac ttcgggtagc gatgctgttc
    40621 gttttcaact tctccgctag gatagatata ttcatagggg tcttgcgtag ctgttggccc
    40681 aagacgctcc aaaataccgt tgaataactg gcgttgaatg cgctggagtg cttgaccgct
    40741 gggtacgatt ggttcgtcca gcttttccat ctcattttct tcgctacgtt gaatttcagc
    40801 ggaatcttct gtatcagttt cattttcttg taattcttgg ttatctattc tttcatcaac
    40861 caccacttga agaggtagtt acccttcgtt cacatcgggg atcttttctg tttcaaaaat
    40921 caatgtgccg gtttctgctt cttttgaata aacttttccg acataccatt cttgaccatc
    40981 gatcgtctcg acttttaggt cttctccatc ttcatcatag gaggatagac ctgttccacg
    41041 aacgtttttt acggtaccaa tcccggcggc tgccgcatcg attgctaaac gtattctacc
    41101 ttcattggca ctttcctttt tttcaaaagc cagatgccat tcaagggttt cttctttttc
    41161 aatatacttc ccttcaattt ttgcatagtc ctcatctaag aatacctcat cctcctttgt
    41221 ttctgttgac tcagcagcta catccagggt cgtcatatga tagactgact ggaaatatgg
    41281 tccaaatagc aaactgacag ttactaactg caaaagcttc aattttaacc ctttcacatc
    41341 cttatactcc tttcaaaaat atttgtcttc tttcacaaca atcaacaaaa caatgcccat
    41401 ctaattataa tttaatttaa ttttaatttt aaatcaaatg atatcctttt tagttaaaaa
    41461 acaccaatta tacaacattt attattaaaa ttaaattata aaattttata acgttctcat
    41521 ttaacaaaac ttaagttatt aagacaaatg aataaacaac tacgctttcc tcgaaacaaa
    41581 aaaataaagc acaaatgcgc atttacgcac tcatgcttta ttcgtacaat taattcagat
    41641 aacggcagcg cataggatgc caataacact tcctaaaata gctcctccta aaatgtcagt
    41701 aggataatgt aaaagtaaaa aaatcctcga ataagcgatc aaacaagcaa ataaaaaggc
    41761 taatattcct gcaactggac ttaattcgaa caacgcagct actgataaaa aggctagcgc
    41821 tgtatgtcct gaaggaaaag aagaagtctt cggtttactt gtgtaaagga caagccgacg
    41881 atttttttca taaggtcttt tccgtcttgt cgtttttttg ataaaaagca aaccaacaaa
    41941 aaaatagatc aaactgccga taagaatggc tagaccatat tctctagtat caggtatcaa
    42001 gactaaaaca gcagcaagga gcaaccaaat aaaaccacca ttagagatat tactgataaa
    42061 tttcaaaaaa ttgatttttc gactatccgt tttccgttgc ttggcgaact tgttgataat
    42121 actatcatcg attttagcaa tcaaacgcaa catgttattc ctccttttta agaacctttt
    42181 cttgcgtacg atggataaaa agcaggactt gaaaataaaa caagaaactg aaacctaata
    42241 aagcaaaata gattggtcct gcaaaccaga atgcgacaag aaggatcaac gtgcctgcca
    42301 aatagaaaag cgcgcttttg aaatcattaa aaaacaagaa aaatgcagta atccaagaag
    42361 cttctttttg ttccagttga agcaagattt tgtaactaaa gagaagcgcg cttaatagaa
    42421 gcaaaaacaa cgtagtatac atcaatgtat agccaattcc cccaccccaa tagcggaaaa
    42481 tctgataatc gatcaataga agaagaaaat aaacacttgc taaactatct tgctttccat
    42541 aaagagagaa gttctcacga aactttttcc agaatagtga accgagcttt ttctcttcat
    42601 ttttttgtaa tgataaatca tatacagaac tgttcgactt gcagttccta atgtgaaaac
    42661 aggcaagacg cacaggaacc atagtagctg taaatggata agacgtggaa tccattcaat
    42721 gatttctaag aaataatcat tggctttttt accaatcgat cgattcatca tccttttgaa
    42781 cctcctgtca aatccatccc ttcaatgaaa taacgttgtg caaaaaagaa cagcaaaatc
    42841 gtcgggatca agacaagtgt tgctcctgcc atcagataat tccattgtgt cgttgcttgg
    42901 ttctgaaaaa cttgcaagcc aatctgtaac gtgtattttt cttgatcttg gatatataac
    42961 agaggaccta agaaatcatt ccaagctgcg ttgaaggaat tgatcgcaat ggtaatcaag
    43021 gcaggtttcg tcaatggaag catcaaatga ctccaaatat acaaatgatt cgctccgtcg
    43081 atttcagcag cttcgatcaa ttcattattg atcgataagt aaaattgacg catcagaaat
    43141 atattgaacg cattgccgaa gaacgatgga acgatcaggg gcaaataagt acctacccag
    43201 ccgatcttgg agaataatac atattgaggg atcatcgtta caaaccccgg gatcatcatc
    43261 gtagaaagaa ccaaagcaaa catcagcttt ttcccaggaa aatcaagctt cgcaaatcca
    43321 taagcaataa aagaatttga aaggacatta ccgatcacta ctagcacagt gatgaataat
    43381 gtatttcttg catagcgcca aaaaggaaag gcggcaatcg tatccagata gttttcccat
    43441 acgatttttt ctgggaaaaa ggtcggagga taacgaacga tttcttccat tggtttcaat
    43501 gaagtaaaca ccatccaaag caatggaatg atcaaaatga ttcctattac tgtcatgagg
    43561 acataactta gtattttttt gtttgccgat tcacactggt ctttttgaaa taatccatca
    43621 tttgccgtca cctccagaat aatagaccca cttaggtgca agcttcaaat tgacaaacgt
    43681 cagaaccaac acgatcagaa acaggatcat tgacatagcc atcgcataac ccatatcaaa
    43741 agctacgaac gccttgttcc acatatgcag attataaaaa agcaaagaat ttgcaggtcc
    43801 gcctgttcca tttttcgtca tgacataagc ttcttgaaaa atttggaaag aaccgatcgt
    43861 agaggtgatc acatcgtaaa aaataatagg agtgattaat ggcaaagtaa tacttttgaa
    43921 ctttccccaa acgcctgctc catcgatttc tgctgattca tataaagatc taggaacatt
    43981 ttgtaatgta gctaagtaaa gtagcattgc tcctccagaa ctccatattt tcatcaaaat
    44041 caacgcaggt ttcgtccatt gtggatcaaa cagccaagct ggtccaggga tatggaacca
    44101 gcccagaaat gtgttgatca atcctgcaga tggagaaagc agctgcatcc ataagatgta
    44161 gactgctact cctgataaga ctgccggtaa atagaaagct gtacggaata cactgattcc
    44221 tttgattttt tgattgagta ctgtggctaa aaacacactg aaaatcgtcg tcagcggtac
    44281 attgaagatg acgaaataaa cggtgttgta taacgatttc caaaataaat catcgtgaac
    44341 gaacattctt ttgaaatttg ctagaccaat gaaattcatc ttggatgtca aattataatc
    44401 ggtgaaacta ccaataactg aaaaaagcat aggccctagc ataaatacca agaacccgat
    44461 aataaaaggc gagataaata aataggccca tcttgcttct tttttctttc ggatagataa
    44521 acgcttcaaa ttttcttgcc tcctctgtac ctagacagtc aaaaatggat tattgatttt
    44581 gcttgactaa gttttctact gctttttgtg catctgccaa tccttctttt ggtgattttg
    44641 ttcctaaaag aatctggtca atctgttcat tcactaatgt cgtgtaatcc ggagcatcta
    44701 aaggaactgg tgtgatcacc gtatttttaa agttttcgtc cgccatttga tagatcattt
    44761 ttcctttatc cgttaggttg tcattattca ctaaattctc attggctgtc ttgctcgcca
    44821 tgatatcaaa acttttttcg ccgaattttt cttgtacttc tggagaagaa agatatttga
    44881 tgaattcata agaggcctca ggatcttttg ctccgtatgg tacttccaag acgaatccgc
    44941 caccccacga ccaatggcct gaaccttctt ctttttctgg gagctgcatc acgccaaaat
    45001 caaaatcatc cggtgcattt tccatcaaac tagagtaata attgatattt tgggcacgca
    45061 tggctactaa tccggaaata aatggatcag atacaccaga cccaaattcg gcttctaatt
    45121 tattgatcgt atttttccca taataatctt gccagtcttg gatccactcc aaggcttcca
    45181 ctttattttt agtatcaatc ttgacttttt catctttgtc aaaccaacta gtcccgttat
    45241 ctgcgtttag cgcccataca tcagccccta aattccataa tggataaaaa ccgatgcgtg
    45301 taaattcttt tccttctttt ttatctagtt tacgtgctgt ttcttctaat tcatcccaag
    45361 ttgtcggtag atcttgttca ctgattccag cttctttaaa tatcttttta ttataaaaaa
    45421 tgacttgtgt atctgtattg aatgggatcg cataaggatc accttcatat tctactgtat
    45481 cccaaagctg cggataaaaa tccttagaag tgtctttttc tacatatttg gagagattag
    45541 ttgcttgctg tgcttctgct ctttgggcaa cggaatttat gtcctgtaca ataacatcgg
    45601 gtgcatttcc agctgttatt gcagataaag atttagtcca gatgtcaccc catggctgat
    45661 acttataatt tacatggatc tcgttttgtg attgattgaa atcctcaatg atttcttcga
    45721 tagcttcttt tcgtgcaccg gatccccaaa aggaccagaa atcaatattt tttcttccat
    45781 cacttgtttt ttcagaagaa tttgctgcac ttgaactggc atcgcttgca ttacttgatc
    45841 cgcatcctcc taataaaaac aatgctgaac ttgccagcaa ccctgtaaac aataattttt
    45901 tcatatttta cctccaaatt ttaatgtaac cgatgccggt tttaatataa cgatatcatt
    45961 ttgttctgaa aataacaatt tataaggtat gattctaaaa aaattattaa tgataccaat
    46021 actttatata attcgcgagc gctttctttg aattttttaa tctttcgtag cagaatgaga
    46081 atgtattaaa aatagattag gaggaatttt gatgtttaga caccagaaag aattgcagtt
    46141 tgaagcaaaa ccagatcgtc cgaatccatt aatcgcgaaa tatctgcagg agctgatcgg
    46201 cggccaatat ggcgagatga gtgtagctat gcagtacctg ttccaaggct ggagctgccg
    46261 aggagaagaa aaatataaag atatgctgat ggacattgca acagaagaaa tcggccacgt
    46321 ggaaatgttg gcgacaatgg ttgctcgttt attagagggt gcgcctgttg aagatcaaga
    46381 agcagcgatg caaaaagatc caacaatcgg tgccattatc tctggaatga atccacagca
    46441 cgcgatcgta gctggcttag gacctcgtcc tgctgacagc gtgggcaatc catggagcgg
    46501 tgcctatatc attgcgagtg gcaacttgtt agcagacttt agagctaatt taaatgccga
    46561 atcacaagga agacttcaag tagcacgtat ttacgaaatg atcgatgatc gtggcgtaaa
    46621 agatatgctg tctgttctcc ttgcaagaga tagctatcat caaaatctat gggaatgtgc
    46681 agtgaaagaa ttagaagaaa aagaaggttc aatcttagtc ccaagtactt tcccgcgtga
    46741 caaagaacga aaagacattg cttatgactt ctataacttc tcagagggag accaaagtag
    46801 tgaaggttct tgggctagtg gcaaagcact ggatggcgaa ggcgaatatc aatggttgaa
    46861 agaacctaag atcgaaggcg ctgcaccaaa attagaacca gtaacaccaa aaatgtatgg
    46921 gacacctcca ttcaagaaat aaatatctac ccgtagaaac acccgttttt tgttccacac
    46981 gctttgtgag caaaactgac taaagtcatt aatcataacc acccttcaaa agggtggttt
    47041 tctctagagc tataagctca aatcaccggc cagcgcctaa agacgctggc tttcatattt
    47101 tatgttcaag ccatattgcc tttgccagtt ttgcccacct cttaaaaggt ttatgtacta
    47161 ctccttagcc cttaaaagga tcgtcttact ctcgtacact cagcttatct aacgcactat
    47221 catgtttttc ttgttcttga atgtactttt tgatggtcgc ttcattttgt cctacttttg
    47281 tcacatagta tccttccacc caaaagtgtc gatacccaaa tttatatttt agatttgcac
    47341 aatctcttga tgatctcctg aatattggct cgatattgat tataaattat ttttcttcta
    47401 tactttggtg tgaatacaat gtggtattta cacatctact ttgtacgggc taaactattt
    47461 ccctttattg ctccacccgc atagcaagtg gttttgtatt tcaatcgctc ggcgcgctca
    47521 attaggtcta aagacaataa atctaaaaac ccgctgcttc actgacagaa acaacgggtt
    47581 ttcagaaaaa aatgaaatga aaaagatctc ttacggcaat ctattttatt tttttgattt
    47641 tttataaatg gaaaatgctt caagaagtcc aagaaataaa gccgtataaa aacaagaacc
    47701 tatgaaatct ttatttatta gatattcaac agaaatcccg ataacactag ccaacaatat
    47761 atttatcaga agtgtaaaat aaggatgctt tttatagaat agaactagtg ttgttttcat
    47821 agactctcct ttcttcatat ttccaattaa tcacaaattc acggcattac tagaaaaatt
    47881 aaaggggcgc agaagtggaa aaatactctt cgactttccc tacaaaccag gccatcttgt
    47941 gtttaataac tataccaaat ctaaggtacc tctaaatcta aattccattt gtggcggtga
    48001 cctccaattt ttaactcttc tatctcccat ccagtataca taaccttgat acttcgacca
    48061 cttatatatc gaacacacaa atacctatcc attgcaggag tactacctaa cttagttgct
    48121 acttgcatct aaataacagc tgaaaagata ggacttactc ttagtaaagt atctgaacta
    48181 ttaattttta aactatcatt tttatcctca actacatgca catctgttgc aacttcactt
    48241 tctgtctcat ccagataaat gattaaggaa tcgggaattg caatatcttc agctgacgct
    48301 ggaatagttg agctaaatta gtcatcatat ctttattata aaataa
//
LOCUS       DADLIO010000014        45442 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.014, whole genome shotgun sequence.
ACCESSION   DADLIO010000014 DADLIO010000000
VERSION     DADLIO010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 45442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45442
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.014"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(<1..250)
                     /locus_tag="JOX41_000924"
     CDS             complement(<1..250)
                     /locus_tag="JOX41_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAY6448686.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQMLKVKEKLTILELKRTR"
     gene            complement(435..1445)
                     /locus_tag="JOX41_000925"
     CDS             complement(435..1445)
                     /locus_tag="JOX41_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAY6448687.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(1625..1969)
                     /locus_tag="JOX41_000926"
     CDS             complement(1625..1969)
                     /locus_tag="JOX41_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAY6448688.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(1962..2396)
                     /locus_tag="JOX41_000927"
     CDS             complement(1962..2396)
                     /locus_tag="JOX41_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HAY6448689.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            2534..3271
                     /locus_tag="JOX41_000928"
     CDS             2534..3271
                     /locus_tag="JOX41_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6448690.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            3264..4475
                     /locus_tag="JOX41_000929"
     CDS             3264..4475
                     /locus_tag="JOX41_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAY6448691.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            4682..5461
                     /locus_tag="JOX41_000930"
     CDS             4682..5461
                     /locus_tag="JOX41_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HAY6448692.1"
                     /translation="MEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAAL
                     SREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLKT
                     MLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHGD
                     VNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDEM
                     LEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            5531..6193
                     /gene="trmB"
                     /locus_tag="JOX41_000931"
     CDS             5531..6193
                     /gene="trmB"
                     /locus_tag="JOX41_000931"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HAY6448693.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(6291..8045)
                     /gene="ade"
                     /locus_tag="JOX41_000932"
     CDS             complement(6291..8045)
                     /gene="ade"
                     /locus_tag="JOX41_000932"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HAY6448694.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            8177..9106
                     /gene="cpaF"
                     /locus_tag="JOX41_000933"
     CDS             8177..9106
                     /gene="cpaF"
                     /locus_tag="JOX41_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component"
                     /protein_id="HAY6448695.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            9063..10112
                     /locus_tag="JOX41_000934"
     CDS             9063..10112
                     /locus_tag="JOX41_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HAY6448696.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            10109..10387
                     /locus_tag="JOX41_000935"
     CDS             10109..10387
                     /locus_tag="JOX41_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HAY6448697.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            10362..10832
                     /locus_tag="JOX41_000936"
     CDS             10362..10832
                     /locus_tag="JOX41_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HAY6448698.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            10849..11151
                     /locus_tag="JOX41_000937"
     CDS             10849..11151
                     /locus_tag="JOX41_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448699.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            11168..11539
                     /locus_tag="JOX41_000938"
     CDS             11168..11539
                     /locus_tag="JOX41_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HAY6448700.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            11511..11870
                     /locus_tag="JOX41_000939"
     CDS             11511..11870
                     /locus_tag="JOX41_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448701.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            12042..13049
                     /locus_tag="JOX41_000940"
     CDS             12042..13049
                     /locus_tag="JOX41_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAY6448702.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            13074..14258
                     /locus_tag="JOX41_000941"
     CDS             13074..14258
                     /locus_tag="JOX41_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HAY6448703.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(14695..16278)
                     /locus_tag="JOX41_000942"
     CDS             complement(14695..16278)
                     /locus_tag="JOX41_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAY6448704.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(16856..16999)
                     /locus_tag="JOX41_000943"
     CDS             complement(16856..16999)
                     /locus_tag="JOX41_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HAY6448705.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(17222..17701)
                     /locus_tag="JOX41_000944"
     CDS             complement(17222..17701)
                     /locus_tag="JOX41_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAY6448706.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(17774..18058)
                     /locus_tag="JOX41_000945"
     CDS             complement(17774..18058)
                     /locus_tag="JOX41_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448707.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(18136..18330)
                     /gene="ssrS"
                     /locus_tag="JOX41_000946"
     ncRNA           complement(18136..18330)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="JOX41_000946"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(18402..19688)
                     /locus_tag="JOX41_000947"
     CDS             complement(18402..19688)
                     /locus_tag="JOX41_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HAY6448708.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            19826..20497
                     /locus_tag="JOX41_000948"
     CDS             19826..20497
                     /locus_tag="JOX41_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HAY6448709.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            20463..20951
                     /locus_tag="JOX41_000949"
     CDS             20463..20951
                     /locus_tag="JOX41_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HAY6448710.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            20964..21911
                     /gene="prmA"
                     /locus_tag="JOX41_000950"
     CDS             20964..21911
                     /gene="prmA"
                     /locus_tag="JOX41_000950"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HAY6448711.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            21912..22676
                     /locus_tag="JOX41_000951"
     CDS             21912..22676
                     /locus_tag="JOX41_000951"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HAY6448712.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            22909..25122
                     /locus_tag="JOX41_000952"
     CDS             22909..25122
                     /locus_tag="JOX41_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HAY6448713.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            25133..25579
                     /locus_tag="JOX41_000953"
     CDS             25133..25579
                     /locus_tag="JOX41_000953"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HAY6448714.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            25750..27009
                     /locus_tag="JOX41_000954"
     CDS             25750..27009
                     /locus_tag="JOX41_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HAY6448715.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(27098..28045)
                     /locus_tag="JOX41_000955"
     CDS             complement(27098..28045)
                     /locus_tag="JOX41_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAY6448716.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            28439..29731
                     /locus_tag="JOX41_000956"
     CDS             28439..29731
                     /locus_tag="JOX41_000956"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HAY6448717.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            29746..31515
                     /gene="aspS"
                     /locus_tag="JOX41_000957"
     CDS             29746..31515
                     /gene="aspS"
                     /locus_tag="JOX41_000957"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HAY6448718.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            31624..32499
                     /locus_tag="JOX41_000958"
     CDS             31624..32499
                     /locus_tag="JOX41_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAY6448719.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            32765..34648
                     /locus_tag="JOX41_000959"
     CDS             32765..34648
                     /locus_tag="JOX41_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAY6448720.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(34723..35007)
                     /locus_tag="JOX41_000960"
     CDS             complement(34723..35007)
                     /locus_tag="JOX41_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAY6448721.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(34997..35731)
                     /locus_tag="JOX41_000961"
     CDS             complement(34997..35731)
                     /locus_tag="JOX41_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HAY6448722.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            35860..36483
                     /locus_tag="JOX41_000962"
     CDS             35860..36483
                     /locus_tag="JOX41_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HAY6448723.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            36675..37796
                     /locus_tag="JOX41_000963"
     CDS             36675..37796
                     /locus_tag="JOX41_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HAY6448724.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            37803..40931
                     /locus_tag="JOX41_000964"
     CDS             37803..40931
                     /locus_tag="JOX41_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HAY6448725.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            40950..44144
                     /locus_tag="JOX41_000965"
     CDS             40950..44144
                     /locus_tag="JOX41_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAY6448726.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(44290..44997)
                     /locus_tag="JOX41_000966"
     CDS             complement(44290..44997)
                     /locus_tag="JOX41_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAY6448727.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
BASE COUNT        14593 a         8055 c         9497 g        13297 t
ORIGIN      
        1 aacgggtacg ttttaattct aaaatagtca acttttcttt gactttcaac atctgagtgc
       61 gtgtcgtata ggaaccgttg cggataatac gaatcgatcc acagtgttca caatgggaag
      121 gtgagtcatc caatctccct ttaataaact gcgcttgaac gcctttatat tctttttcaa
      181 tcagccattc ttcatcaaaa aataaatgtt tatctgttaa tccgagtaat tttctagtat
      241 gattatccat tgagagactc ctttggtagg gtgacgtttt ggtcgactaa attttaccaa
      301 aagtgagtct ctttttgagt tgaaacgaag aaaaaagtgt tagtagaaaa tcgctttcga
      361 ttttccacca acacaaaata ttatagaacc aacaaaaaaa gcgagacata agtcttcgct
      421 ttttttgttt tcttttattt tgatgaatca gttgtttctt cagttgaaga ttcttttgtt
      481 gaatcagttg attttgtgtc agaactcttt gttgaagctg tagtttcact tgagtctttc
      541 gtacttgatg aagttgttgt gaatgcactc aacacatttt caaaggcatc atctttgatt
      601 tttacatttg catcttttaa ttcttcaccg attactttag ttgtgaatgc attgtcactt
      661 agtttagttt cagtagcgat atcttttagt tgatctttgt atttatccat gtcattgcct
      721 ttattttggt ttttcaccat tttgacaacg tagtattctg tcgcataaga agtaggattt
      781 gttgtagtaa taacatcgga gatctcaccg tctttcaatt tgaaagctgc ttcttttact
      841 tctgcaggaa tagttgttgt cgttgagtcg aatttaactt taccgccatc ttcttttgtc
      901 tctgtatcag ttgatttgtc tttggctaat ttagagaaat catctccatc atccgctgat
      961 tttttcacat cttttgcttc atcttcactt gataatttga tgatttgtgc ttctacttct
     1021 ggatggaaag atttccaagc agttttcaaa tcgtcatctg taatatctac gtgagctttc
     1081 aagccagctt caaaagctaa attgttacga atatattctt tataagtatc tttcgtatat
     1141 ccagcagctt ctaattgtga ttcaaaagta tcacctaatg atttcgcttg tttgtcgtat
     1201 tctgcatcca cttgcttatc ggttacttta tcgccatatt tgttattgaa tactttataa
     1261 atgatcatcc gttgtactaa ggattggttc gatgattcaa gttttgcttc atcatagaaa
     1321 tcagatacag tgatcgttcc gcctttcatc gttgcgatat ctttattagt atcgcctgaa
     1381 caagctgcta gagttaaaac agccaacgca ctagtagctg ccaaaataat tgattttttt
     1441 ttcattaaaa tttgcactcc tgtaattagt tattattttt atatattaac tataccatat
     1501 cccatttcct ttaaaaacgt tgtcgtggta gtttcaaaca aaattcaaaa tttcatcaca
     1561 ttcctaggaa atacgcaaac ttttctcact tatatagtta aatctgttga gaaaataatc
     1621 attattatat ttgttcagga tactctggca gatcagcttt tagtttttct acttgttcat
     1681 tgatttgtgt gatacgtggt tcggcttgga atttaaaatc ttcgatatct tttttgattg
     1741 cttcttggaa agcaggaatc acagattcag ctgtttcttt tgtttcgatc aatgcgcttt
     1801 taaaatgatt caggctgtta tttaaatcat ttgtcagagt tgttgcttct tccaattctt
     1861 cgatcagttt ctttcttgtt tcattcccgc tcctgggcgc caataacaga cctccgacag
     1921 tgccagcagc agctccaaat aacagtcctt tgaaaaagtt tttaatcatc gcaggacacc
     1981 tgctttacga ttgtttcttg aatagctttt agttcttccg atccataact atcttgatga
     2041 ttgacaaagt gaatagaaaa atcatcctct ttgctgtagc gagggactaa atggatatgt
     2101 gaatgaaaaa cagattgata ggctagttca cggttgttat tcaagatatt aagacctttc
     2161 atttctggaa aagctttttc caatgcttga gcaatcttag gcacacgcga aaaaacctct
     2221 cctgcaagtt cgggatcata ttcaaaaata tctgctacat gacgtttagg cacaactaat
     2281 gtgtgtcctt tcgttgcttg agagatgtct aaaaaagcat agaccttgtc gtcttcatat
     2341 attttatagc ttgggatttc ttgattgatg attttgcaaa aaatacagtt ttccatataa
     2401 aacatccttt ctataaagaa taaatacttc agcttaactt taccataagt taaagctatt
     2461 gtaaggaaaa aaacaaaata ccgtcatttt cttcgtggta taataaataa aaataaatgg
     2521 cggaggaaaa agaatgagtt taattatcga tcatgtcaca ggggggtacg gacatctccc
     2581 tgtgttaaaa gatatcagtt tcgatgtaca gcctggagag atagtagggt tgattggact
     2641 gaacggagca gggaaaagta cgaccatcaa gcacattatc ggtctgctgg aagcttcaaa
     2701 aggaacgata gaaatcaatc atctatcctt aaagaaaaat acggaagaat atcgcaaaca
     2761 aattgggtat attccagaga ctccttcttt atatgaagaa ttgacattga gagaacatat
     2821 cgaagtcact gcgatggcct acgatatacc tatggatata gcaatgaaaa gagcagaaaa
     2881 gttgttggag acttttcggt tatctaatcg tcttgactgg ttcccagcta atttttcaaa
     2941 gggaatgaaa cagaaagtga tgatcttatg cgcctttttg atcgagcctt ctttatatat
     3001 catcgacgaa ccatttttag gcttggatcc actagctatc aatgcattgc ttgaattgat
     3061 ggtagaaatg aaaaaagaag gagccggtat tttgatgtct acgcatattt tagctactgc
     3121 agaaaaatat tgtgatcgtt ttgtggtctt acataacgga gagatacgag cagacggttc
     3181 tcttgagatg ttgagaaaag aatttcagct gccggattct tctttggacg aaatctatat
     3241 tgctttaaca aaggagcagg cacatgagta gtttttttca aaaacgttta gcaagacatc
     3301 aaaagaaaat gatgaaatat atgcgttatg tattgaacga tcattttgtt ttagtttgtc
     3361 ttttcttgat tggcggtgtg ggattatatt attctaattg gttgaaaacc ctgcagccac
     3421 cgtttgcaat tggagggctc ataatctctg tattttggat gctctgttta ttcgtgggta
     3481 agatggctac ttttgcagag gcagcagata ttgttttttt acttcctaaa gaaaaagaaa
     3541 tgcaaaccta tttggaacga gcttttcgct attcttgcat ttttccgttg atctttttga
     3601 tattggcatg cggattggcc atgccattag tggtggttag tacggagcaa tccttttcga
     3661 tgtttttcgt ctatctgatc atattatgga gtttgaaatt cagtcatctg caaatcaaga
     3721 gagcagaatt gtttcgacta gatcaacaag ttattcgtta ttggaaatta ggctggtttt
     3781 tttcttctct gatctttttg tttctatcat tttattggct aatatgggca ggaatagcag
     3841 gtgcattagt acaggcaagt ctatattact ggtttttgtg gaagcaacaa gaaaaaggat
     3901 tggattggga gaaaatggtg catgtagaag aacataggtt gcatcagatc tatcaattta
     3961 tcaatttatt cacagatgtt cctgaaatta cggcaaagat caaaagaaga cgctatttgg
     4021 atcctatatt gactcatatt aaaagagaat caaaaaacac ttatctttac ttgtttgcaa
     4081 gaagattggc aagaggttct gattttagtg gtctttattt ccgattagta attataggtg
     4141 ggttattgat tgccggagta gtcgactttt attttagtct gattatcggt ttcttatttt
     4201 tatatttgat cggtttccaa ctgttacctt tagcgaacca gttccgctat atggttctcg
     4261 ttcagcttta tccaatccat aagaatcaga agaagcaggc gattcagtat ctactcacat
     4321 gggtattaat tatcgcgtcg gttatttttg gtttgattgc tgcagtcgta ttagatgggc
     4381 agcagcgatg ggttccgcta gcggcttatt tgattgttac tatgctcttt gttaaactat
     4441 atgtaccaac tcgtttgaag aagatgtcag actgaaaaca aagctgtgta gggtaaaaat
     4501 gagaatgaaa aatagagcgt tgacagtaag aatgctgttc gttctatttt ttttgagaaa
     4561 agctggtttt ttgaatggca attaaatgaa aaagaacgta tatgtgcttg acgtgtagtg
     4621 ttcaggcgac tagaataata agtactgcaa aacaaagagt aagaggacgg gagaatgcat
     4681 gatggagttt cagttagacc aagagtggcg gttacgtccc atcaaaggcg acacaggaaa
     4741 aacatacata ggcatgcgtg atgaggacaa agtctttatt aaacgaaaca cgactccgat
     4801 gttggctgct ctttcaaggg aaggaattac accaaaactt gtttggacaa aacgaacggg
     4861 gaatggcgat actttgacag cacaagagtg gctggaaggt cgcttgctga ctcctaatga
     4921 gattggtcaa agaaacgacg tgattgatgt tttgtaccat ttacatcatt caaattctct
     4981 taaaaccatg ctgacccgta tcggtggtcg tgtcatgacg ccggagaaga tgctgcaaaa
     5041 atatgaaaaa gaattaccgg aagaactcca gaaaaatcaa tttctgcaaa ttgtccatcg
     5101 ttttcttcgt gagcagatcc cgtcaataga taaggaaaac ttatcagtag tacacggaga
     5161 tgtaaaccat cgtaattggt tagtatgtaa aaattattta tatctagtcg attgggattc
     5221 aatcatgttt gcagaccctg cggtggatat tgcaacgatt ttaggaaatt atgtgccact
     5281 gtctagctgg aatcagtggc tgatcagtta tggcatacgc ccgactgacg aaatgcttga
     5341 aaaatttcat tggtatgcgg ccatgaattt gctccaagaa atcaccagat attgcaaacg
     5401 tgaagatcat cgacggatga acgaagaaat tttacaatta aaacgaattt tcagtggctg
     5461 aggtttggcc caaactctgc ggagatttgg ccagaccttt ttaattagag gaaaggaatg
     5521 gagataaata atgcgtgtcc gaaatcgtcc gggagcagcg gaaatgttag cggctcaccc
     5581 gaattttgta attagtgatc caacattgtg gaagggaaaa tggaatgaat tgtttgaaaa
     5641 cgatcatcca atccacattg agattggtat ggggaaaggc cagttcatca ctggaatggc
     5701 aaaagcccat cctgaaatca attatattgg agtagaaatg caggtcagtg ttgtttcgat
     5761 tgcactagac aagttgatcg aacaaccgct tcctaacctg aaacttctac atgtggatgg
     5821 atcagcgttg acagagtatt tcgctgacag cgaagtagat caaatctatc tgaatttttc
     5881 cgatccatgg ccaaaaaaac gtcatgaaaa acggcgattg acatataaga cttttcttgc
     5941 tgtagatgaa cagattcttc gtccaaatgg agaaatccat ttcaaaacag ataatcaagg
     6001 attgtttgag tattctctgg caagtttttc tcaatatggc atgatcctca aacaggtatg
     6061 gttagattta catcaaagtc aatttgaagg caatattatg acggagtatg aagaaaaatt
     6121 ttcttcaaaa ggtcaacgta tttatcgagt agaagctcaa tttcaagata agaccaaaaa
     6181 gaaaagtctg tgaaactaac tttctgcttt cataaaaaca ttaatatcca taaataaatc
     6241 ccagaaaatg aacattacag atgtaatgta ttttctggga tttatttgat ttaaaatgta
     6301 tttatttcat cggtttttcc acaaggtgga atcaattgga agcgagaaaa tgaaaataat
     6361 cctttgtcgg tgatcttcaa ttcgggtatg acagataatg ttaagaaaga aagtgtcaaa
     6421 aaaggatcaa aggttttagc tgctcctagt tgatgtgctt tagttattaa ttcattcaac
     6481 tgttcataga cgatcgaaaa aggttcctgt gtcatgattc cgcctatagg aagagaaaca
     6541 caagctattt cctgctgttt gttgacaacg gtcatcccgc cacctttttg aatcaaaaga
     6601 ttagcagcat acagcatatc ctcgtcgttt gtcccaacga caactagatt atgcgagtca
     6661 tgggcaatcg ttgtcgctat cgctccttgt ttcagctgaa atcctttcac tatgcctaat
     6721 ccaatgtttc ccgtttgatg gtgacgctcg atcaccgcaa tctttaattg gtctttttcg
     6781 attgaaggaa tgaatcgttc gccttgtcgg tccacttttt ctaccaaatc tttagtcact
     6841 agactattcg ggataatttc gatcacatgg gcttgtgaag aagaaagaag cagctctaac
     6901 gaatgtggat ttaatggttg agcgtttagt tttggcagac aacacgtata tgaatttgaa
     6961 tgatcagcaa ataaatggtc ttggagttgc ccagattgaa caactaatgt tcccttatag
     7021 aaaacttcat gaattggcag cttggtaaga tcgtctgtta agaagaaatc agcttgatac
     7081 ccaggggcaa tcgcacctag tgttttcaaa tcaaaacatt ctgctgcatt caatgttgcc
     7141 atctgaatgg cttgtaatgg atcgattcca agtgcaatag cttgacggac gatatgatcg
     7201 attgatcctt cttttactaa atcattgatc agtttatcat cggtgacaaa gaagcatctt
     7261 cttgaatttt caggtgtgat cgccggtagt agcgatgcca gatcttttgc aacggtccct
     7321 tctcgaacca ttaaatacat accaagatcc aaacgttctt tagcttcttt tgcagttgta
     7381 gcttcatgat ccgtccgaat acctgctgca ggataaacat ttaactcttc catgccgata
     7441 ccagctgcat gcccgtcaat ttttttctta tgctggtgca tcaattggat cttttctagg
     7501 atgtctgttt cattatttgc tactgcttga tagttcatga cttcagctaa gcctaaaact
     7561 tcgggttttt gtaaaaaagg ggctaatttt tttgcattta aatttgcacc attggtctca
     7621 aaaggggtta caggtacaca agaaggtagc ataaaaaaga tattcatgag tgtttgtctt
     7681 gcatcttcta tcataaactc aagacctgta ctcccagcaa tgtttcctat ttcatgggga
     7741 tctgtcacta cagtagtaac tccatgaagc aaggatactt ttgaaaattc gcttggtgat
     7801 aaaagtgagc tttcgatatg cacatggcca tcgatgaatc ctggcactag atattgccca
     7861 ttagcattat gtacgctttt tccttcgtat tcaccgattc ctacgatcat tccttcgcag
     7921 attgctacat ctttttccat gatttctttc gtaaagacgt tgacgatctt agcatgcttg
     7981 atcactaggt cagcaggctt ttttttactt gctacttcga tatatttcct taatgttgtt
     8041 tccaatggag tgcctcccaa gataaatttt tataagtata acataaattc ggtttttgcc
     8101 aatatttttt tgtaaattca ttttatttga aacaaaaaga tcaaaaagac gtatgttttt
     8161 tgtggagggg agaataatgg aaataaaacg attatcggat caaatgataa gtgaaagttt
     8221 tgccaaacat gcccaagacg tatatatatt gccagcttca gaagtatttt acatctattt
     8281 tcgctatgga aaaaaacgaa cattctggaa gaaagtctct tcggcagatg gacagcaact
     8341 gatctcaaga tttaagtatt tgggacagat ggatatcgga gaaaaaagaa aagctcagtt
     8401 aggtgcattt acttattctt tagaaaaaca ggaagttcgt ctgcggttgt cttctgtagg
     8461 agattacctt caacgagaga gtttagtgat tcggctatta tacggtactt ttgaaacacc
     8521 ccatcgttgc tttagttctc gagattttgc aactatttta cagaaaaccg tcagacgtgg
     8581 attatacctt ttcagcggac cagtcggatc aggcaagact tctctaatgt atcggttggc
     8641 tttggaagaa aaattgcaag tgattactat cgaagatcct gtagagatag aagaaccgtt
     8701 ttttctgcag ctacagatca atccgaaaat agcacagact tatgatacac ttttgagact
     8761 cgcattacgg catcgtccag acttgctaat cattggcgag ataagagatg aatcaactgc
     8821 acatgctgcg gtaagagcag cactaacagg gcaccgggtt tttgcaaccg tacatgcacg
     8881 caatcttgaa ggtacattgg tcagaatcca tgaactgaca aagaaaaaag aagagctatc
     8941 tgaatgttta gctggtgtca tttatcaaga acttttggaa gatgccaatc accatccttc
     9001 tgttttatgg agttatcaat ttatggagga agaatcagta aaaaaatcat gggaggaaag
     9061 ttatgaagaa gctcaggaaa atatttggca gtcagaacta ttctaaagga ttaacaagaa
     9121 gccagcaaaa ccagtttgca caaaccatgg gagaactgct tttatctggt tttagtctgc
     9181 aagaatccct ttatttatta ctcacgatcc gttcgtttcc acctgttatt ttggcaaata
     9241 tccaacatca gctaaaggaa gggcaagcgt ttagtgaggt actttcgcaa ataggatatg
     9301 gagcagagca actggtacag atcgagttag ctgaacgtca tgggaatctg ccgacaactt
     9361 tgttggaaat tgccaaacag tttcggcttg ttgaaggatt tcgcaatgat ttgaaaaagc
     9421 tgcttgcata tccgatgcta ttgctcacct ttttgctagg tatcttgttt agtatgcggt
     9481 tgttcgtttt gcctcagctt attggttcag gaatggtcat gcaagagcat tggggtattc
     9541 agctgataca agtctttcat tggtatgttc tactattcat cctagcggtt actctattgg
     9601 ctttactagt aaggtatcgt ctgatgaagt tgtctcctgt tgatcagagt gaatggataa
     9661 gcagacaatt attgattgga ccgatatatt ccttgtatca atcggcttat ttgtcactag
     9721 agattggaaa gctttttcat gaaggtttcg aattaaggca aatcatagtc tgcttaaagg
     9781 aaacgaaaca agaaagtctg attcagcatc ttgcctctaa gttgattcaa ggattggagg
     9841 caggtatgtc attggctgag cagttccaga attatcgttt tctatcagaa gaattcagta
     9901 aaattgtttt acagggagag gcaaagggaa gtttaggtaa agaactgatt ttttacagcg
     9961 aatggacaag aaaacagctt ttcaaacgtc ttcatcactg gatgcatttt attcagccaa
    10021 tcattttttt gggcgtagcg gctttgattt tattagttta tgccgctgtt ttattacctg
    10081 tttacggaag catagaggag gttttgccat gaaaaagaga aaaatatctt attatagcgg
    10141 ttttacattg atcgaaatgc taatcgtctt actgatcatc agtgtattag tgttgttgtt
    10201 cgtccctaat ttgtcgcgtt ataggaatca tgtagaccaa gaaagtcgtg aagcgatcat
    10261 ccagttggta gacacacaaa aagagctcta tgcgcttcaa aataatggaa gagttcctac
    10321 tgtggaggaa ttgttgaatg aaggctatat caaacgagaa catgcagaaa tctatcagcg
    10381 gccttgaagg taaggtttta gcatcaggat atacgttgtt tgaatcactc ttactgattt
    10441 tattacttac aacgatcctt tcttttccag ttctcgcatt ttctgcatgg aagaatgaat
    10501 tggcagtcta tcaatttttc ggccaatttg aaaaacgaat ctattctacg caaaaaatcg
    10561 ctattgtgaa tcagatccaa acaggctttt attggaatag tgaagagaat caaatcattt
    10621 ttcatgttcc gaatccagat aaaataaatt gggaagtatt agatattcct gatgagatta
    10681 ccttgaaacg ccatgcttct attacttttg ctgctagaac cgggaatgaa agttcactaa
    10741 aagcttatca attttattgg gaagaaaaag agcggacgat tacgtatcaa ttccagatag
    10801 ggagtggtcg ctatacaaaa agaattgaat aaaacaggat ttgttttgtt ggagtccctt
    10861 acagcgctta tgatcgcttc tgtctgtgtc tacttagtga gctttggcca gctgtttttg
    10921 cttcaggcag aaaagaaaag tggggaggaa ctgctattta ttcgaatgat ttatgaagat
    10981 atcaagacgc agcggatgta tcacaaaaga ccagagcgaa gggaagaaat gatcccatac
    11041 gatatccaaa ttgtcgataa taatggagta atcgaaaaag tgtttgtcaa tatggagaaa
    11101 gaagcgatca gtattgaaaa aacaagtaat tccagcattt acgctgattg aatgtctaat
    11161 tggactgatg atattgagca gtctattgct cacattcaat cttttgattc agcaaaccat
    11221 ccaagtaagt gaatttttgc agcgtaaaga tcaaaaagag tggctaatat ttttagcaca
    11281 attagaagaa gaactcaaga gcagtcacaa tgtctctgtg aaaaatcagc aactgcacta
    11341 cacgatcgag gataaacagt atatcatcga aagatatcag gcaatgatac gtaaaagaag
    11401 aacttccggc ggacatcaac ctatgttaac aagtatcact gagcttcaat tattggaaaa
    11461 agaacacaca atttcttttt atgtacactt tgaaaatgga gaagatggat atgccatatg
    11521 gacaaaaaac gatcagtaga aaatgttata agggctctat tttattttct gtcttgcttt
    11581 tatttctttt atgtacgttt ttattgatgg cagcattaga aagctaccgt ttgtcaatgg
    11641 atcttaatat acgaatcaaa aattattata tagcaaaaat aatgaagcag atggctttat
    11701 cggaacagtc tacgcttgcc gaaagttcgg aaggagtttt ttactacaca actggatctg
    11761 taacatatca gtgggtacaa cagtccctat tcttagaggt ggaagtctca ccgtttatct
    11821 ttcggttcac agaagaagta aaaaatgata cagatactag tacagaatga tggaatgttc
    11881 gtgaaaacgc cctcttttct gttataacac tgtttttaat aaaaaaatgt ttgccgtttc
    11941 acaaataaaa aacagtgaaa acgattgaaa ttttgtcaat tgttcgatag aattaaacag
    12001 gtgaaaaaat tgttataata tatctagaaa tgaggtgcac catgttacca gaaaaaatgg
    12061 aacaagggtt taatcaaaac ctggaagcta ttcagctttt acagaatgca ttgggaactt
    12121 cctttttaga agcctatgtc gaaaatgcag aaaatttaat agatgattat caagtacgtg
    12181 tggtggatgg agtgccgaca aaagagacaa cgcaacggat cacagctctt tatgaagagt
    12241 tgaagaaact ttctttcgag ccagaagaat ggcgcagact gtctcaatta cttttattga
    12301 agggcagcca gacagaacat ttgcaggcga accatcaact cactcctgat agtatcggtt
    12361 ttttatttgt ttttcttatt gaacaactat acacaaataa aaaagcaccg gttaagattc
    12421 tggatattgc ggcaggaatg ggcaacttgt tattaacagt tcttttaaac ctatcgaatg
    12481 cggggtacca aacagaagga attggtgtgg atattgatga tacattgttg gctgtcgcag
    12541 cttctacaag tgatttgaca caagcaaatg ttcaatactt tcatcaagac gggttgcagg
    12601 aattattaat agatcctgtc gattttgcaa tcagcgattt gccaatcggt tattatccga
    12661 atgacgaaaa agcaaaagag tttttaacaa gtaccgaaga aggccatagt tatgcacatc
    12721 atttattgct agagcaatca atgaaatatg tgaagccgga tggttttggt ttgtttttga
    12781 tgccgagtgg atttttagaa acggatcaaa gtgaagaaat caaaaaatgg tttaaagaag
    12841 aaggttatct tcaaggaatg attcaattgc cagatgaatt gttccgtaat aaacaatcgc
    12901 aaaaaagtat tttgatctta cagaaaaaag gaccacaagc acaacaagta aaagaagtct
    12961 tgcttgtgaa acttgcttca ttaaaagaac cagagaaggt gacggaattt ttcaacgagt
    13021 ttaaaaactg gaaatcatct gctctgtaat cattcaacga gaaggagagt catatgtcta
    13081 aaacaattgc aatcaatgct gggagttcaa gtttgaaatg gcaattatat caaatgccag
    13141 aagaaaccgt agttgcgaaa gggatcgtcg aacgtatcgg tttacaagat tctattttta
    13201 ccatcaagta cggcgataat caaaaattcg aacaaatcat ggatatcgaa aaccacgaag
    13261 tagcagtaaa aatgctgtta gatcagttga ttgaactgca aattttaagc tcttatgatg
    13321 aaatcaccgg agtagggcac cgtgttgttc acggaggaga aacttatggg gattcagtag
    13381 tgatcgatga gaaagtaatg gaccgcattg ctgaattagc agaatttgct cctttgcata
    13441 atcctgcaaa cttaatgggg atcaaagcgt ttaaaaagat tttacctgac attttgagtg
    13501 tggctgtatt cgatacatct ttccactcaa caatgccaaa gcaaaattat ttatatagct
    13561 taccggtgtc ttattatgaa gatttcaaag taagaaaata tggcttccat ggcacaagtc
    13621 atcgttatgt gtcggaacgt gcggcaaaat tattgaacaa accgatcgaa gaactaaaaa
    13681 tcatcacttg ccacttagga aatggtgtat cgatcacagc agtcgatgga ggtaaatcca
    13741 tggatacttc tatgggattc acaccattag ctggggtgac aatgggtaca cgttcaggtg
    13801 atatcgatcc agctgttctc ccatatttaa tggaaaaatt agagattgat attgatgaaa
    13861 tgatcaatgt tttgaacaag aaatctggtc tgctaggcct aacaggattg tctagtgata
    13921 tgcgtgatct tgaaaagaac tatgaaaaag aacatattcg tttagcttat gacattttcg
    13981 tggaccgcat ccgaaaatac atcggcggtt atgtgacaac gatgaatggt gttgatgcaa
    14041 ttgtctttac tgctggtatc ggcgagaatg acggacatgt acgtagtgaa atcatcaaag
    14101 gtatgtcttg gtttggttgt gaaatcgatc cagcgttgaa tgaattgcgt ggtgaagaag
    14161 tagatatctc tacaaaagaa tcaaaagtaa gagtattagt gatcccaaca gatgaggaac
    14221 taatgattgc ccgtgatgtg gagcgtctgc gcggctaagc caaagcattc gttaggataa
    14281 aagatgaaac gcatgcaaga gggaattctt gcatgtgttt tttttgcgga gaagaccgca
    14341 aaatggtaat ttaacttcaa tttcccttct tttttacagg atcttcttag ggaattttgc
    14401 ttggaaaagt ggtcaaaagg gaaaagactg gcattttatt tattgatttt caggaaaatc
    14461 ccaatatttt attttcattc atctttataa gggacattac atatgtaaaa agaaaaaaca
    14521 tttttagatc agcctcgtgg gctgtcgact ttattcttcg ctttatgttt agctagaaaa
    14581 ccgatccgaa acattcattg atcgaataat aaaaacttga ttttccacct gtactttgcc
    14641 tgaatcgtga aagcacaggt atgaaaatca agttttttgt tgcgaaaaaa cgtcctagtc
    14701 aatcagttgg ccgagcggct ggcggctgat ctgctcctga tcaataacga gtgcttcttg
    14761 gaagtgttgc tgcaaaaagt agcggtcatg gctgactgct aggagcgttc cttgatagtc
    14821 ttgcagcatt tcttcaattt cttctcgagc atagctgtcg aggtgattgg ttggttcatc
    14881 caaaatcagg acgttgattt tttctaaaaa gagtttcagc aacgccaaac ggattttttc
    14941 accaccggat aaatctttga tccgtttacc cacatcgctt tgataaaagc cacttttggc
    15001 taattgccgt cgagcgactt cttcgtttcc agtcaatgtg atggcgtaag ccagcaaacg
    15061 gctatcggga tcggcaaact gcagctgctg cggcaaataa ccgatttgca agctactacc
    15121 taatttgatg gtgccaccgt aaggcttttc ctcaccgagt aataatttga gtaaggttga
    15181 ttttcctgca ccattgtcgc cgatgatggc taaatgatct ccacgataga ctgcaaaact
    15241 gctgtctttg aatagtactt gatcagcgta ctgctggtgc aagttttgaa tgatgaaaac
    15301 ttctttgcca gattttccac cattagacaa gctttgcagc cgatttttcg ggggaggtgg
    15361 cggtttgacg agtgtcagtt tcgccaggcg gcgttccagt tctttggctt ttttgaagaa
    15421 ggactcattg tctccttcat gtgcccactg acgaaaacga cgaatcatga ctttcaaccg
    15481 ctggacttct ttttgctgca gttcgtaatt ttttgtcagc tcagccaagc gagcttcttt
    15541 caagactcga aaacggctgt agtttccggg atactcaatc aatgcacctt cttccagttc
    15601 ccatgttttt gtggtgactt gatcgagaaa ttgccgatca tgagaaacga ccagaaccga
    15661 tttttttgta ttctgtaaat agttttccaa ccagcgaata ctgttaagat ctaaatgatt
    15721 ggtcggttca tcgagtaaaa gtaaatcggc atcggctgct aaaattttgg ctaaagcgac
    15781 tttaactcgt tcgcctccgc taagttctgt taaccgtgct tcctgacggt gtggaatccc
    15841 taagccttgc aagatcgctg caatccggtc ttctaatacg taaccgccta gttcttcaaa
    15901 gcgatgctgc agctcaccgt aacgggccag acacttctct aagtttgtat ctggttctgt
    15961 catcaatgct tcgtagcgac tcatttgctg tttgaggtcc tgtatctcag cggcagaatg
    16021 gagcaagtag tggttgacgg tcgcttcgga aactgtaagt tcttgttcga ccgtcccgat
    16081 ctttaagcct tttttgcgac tgataacacc gctgtcgaca ccttctctgc cggtcaagat
    16141 ttgtaaaaag gttgatttgc cagttccgtt gataccgact aaggcaattt tttcaccagc
    16201 ttcaatttga caggataaat cctcaaataa tggattcccg ccgattgttt ttttaataga
    16261 aattgcttgt atgatcatga tctctctcct tgagaccact caaaaaggcc atggttatcc
    16321 atggcctgtg ttatttaaac tcagattatc atgagaaaaa taccttgaga tggccattga
    16381 ttttacgtga attcaactgt tttggacaaa cttgtcccgt caacagcaac tgtaaaacca
    16441 attgcatggc taaatgcgat atggtatcgt tggtaatttt cattacttgt tattttagtc
    16501 atgcgcatca tagtattttc cctccttcgt gtagttgtct tttccagtgt acctgaaagt
    16561 gtcagaaagt tcaactagcg ctgacattta cttaatattt atcgatgtgt aattctgtca
    16621 gagagctttt tttatctgac tgagggtaat gtctcgtgga ccacatcatt gtattctgag
    16681 ctaaaccagc gttcaggcga aatcatatgg tgtttgataa aaaactttgt ctacatgact
    16741 tccttttgcc atttgcttaa taccgttgca ttaaacagct cttctctttg gaaatctcac
    16801 caacatcgcg ttcaggagta tcgttgtggt tgcaatggca agcggtagcc tttcatcaat
    16861 tcttgaatga tttaccgaat gtagcacttg ccttctcgcg gtacccgaac ccgaaataaa
    16921 attttagttt ggcgataaaa tcggtatccg ccatcgatac ttcatatttt ttcgtatcag
    16981 attcatcgga aacttccaca ttgacgaacc aataagcttt ggcatgctta ggtcgtttta
    17041 aaccacacca gggcgactaa tcgccctggt gttcactttt ttttatttta cttgaactca
    17101 ttgactgttt tccctttatt ttaaacatta taaagaccga tgagtgcttg ccgcgtcttt
    17161 tgtttttatc acggtttttt gtgcaaaaaa acctgccgat agttggcagg tcgtctacgt
    17221 gttaagcttt ggtgtggtct ttagctggca attggttttc taaatcagtt cggacaacaa
    17281 gcacatcgca agctgcgttt ctaataacat attcagaaac agaaccaata aataaacgtt
    17341 ctacagcatt caatcctgtg gctcctaaca taatcaaatc tacttgatta tcttctggga
    17401 tttctctggc aataatttgt tttggtgagc catattctac gacagaggtt acattattca
    17461 agccagcttt cttcgcattg ctttcataat ctgccaatgt ttgctttgcc atttcagtag
    17521 cttgttctgc aagcattcca tcaaaggatg aaacggtttg gaaagaacgt gtgtcaatga
    17581 catgtgctaa tagaagttct ccgttatttc ggatagctac attgaccgcc tttttaaaag
    17641 ctaattcagc ttcatcagaa ccatctacgg caaccatgat ttttttgtat tgttgtaaca
    17701 taagcattca ctcctcaagt caatcgtatt gtactctttt attgtagaac actttaggga
    17761 aaaagagaat tatttactgc tttggttcag caattttttt tgcaaatcgg atactgaagg
    17821 tggcagaaac aataattacg atcagtaaaa agaccaaggc aataaagcgt tgattgaaaa
    17881 aagctgttaa aatacccatt acgcctaaaa cagcatatgc agctccgtaa aattgtagga
    17941 atccttgatt tttatcattt ttgttgatca atacaaaaaa gatatcctgt ttattaaata
    18001 aataatagct aacgaataat aatactaaag tggcgataat cattaaaatc ctaatcatga
    18061 acaaatcctc caaaataagc aacaaataga aaaagcaatt tgccaagagc aaattgcttt
    18121 attctttaaa agatggtaat ctccgttaat gccgttgttt gtcctgtagt attgatcccg
    18181 cgaattcaag caggtgggtc ccatggtcgt agcttcgaac taccaaatga taaggcatgt
    18241 taccagcagt gacacaagac gggtcccaag atatcaataa aaatgttcgg tcaacacaca
    18301 aagaggacaa ttcgaacatc acagatttcc cacctctata gtagcatatg aatttaaaaa
    18361 gagcaatgag agagctcgca gaaacagaac cgttttcttg tctagttttt tggaggatgc
    18421 tttttccact cttttatacg gtaatactgt tgacccagag cctgttcata tttccctgta
    18481 tcttttggct gataatactg agcattcttc agtttatctg gtaaatattg ctgattgacc
    18541 caagcctgat caaaatgatg aggatactga taacccacgc cacggttgag tgatttcgca
    18601 cctttgtaat ggctatctct caaatgatca ggaacatctc cagctttgcc ctctcgaata
    18661 tcagcaagtg ctgcatctaa tgccatgtag gcagaattgg attttggcga caagcaaaga
    18721 tcgacgacga cgtctgctag tgggatacgt gcctcaggca atcccaattt ttcagcagct
    18781 aatacagcgt tcactgtacg agccgcagca gcaggattac ctaaacctat atcttcataa
    18841 ccgataacca tcagacgccg gcaaatactt gccagatcac ctgcctcaac taaacgggcg
    18901 agataatgaa gtgcagcatc cacatcactt ccacgaatcg atttttgaaa agccgaaata
    18961 acgtcataat gagcatctcc atttttgtca tgggtaagag cttttctttg gacacattct
    19021 tcaatgatcg acagtgtaag atgaatcctt ccttctttat ctgaaggagt cgatagtgta
    19081 gccagttcca gcccattcaa tgcactccgc aaatcgccgt tcgttgcacg cgaaaggtga
    19141 agaagagcat cttcgtctaa ctggattgct tgttgtccaa ggccgcgttc tttatccctt
    19201 aaagcatgtt cgactgccaa ctggatgtct tgttctgtta atggtttgac ttcaaagatc
    19261 tgtgtacggc tgcggatcgc tggattgatg gtaatataag gattctcagt agtcgctccg
    19321 atcaagatga ttcggccact ttctaaatga ggaagcagaa aatcctgttt tgttttatct
    19381 aatcggtgta cttcatccaa taagaggatc actgtaccac tcatttttgc ttcttccgct
    19441 acaacttgta gatccttttt tgaatctgta gcggcgttta gcatgcgaaa tgcataatta
    19501 gtagagccgg cgatcgcact tgcgatactc gtttttccag taccaggagg tccatataga
    19561 atcatggaag agagcatgcg agcatcgacc atgcggcgta tgatttttcc ttccccgact
    19621 agatgctgct gaccaacgac ttcatcgatc gttcgaggtc tcatgcgata agccaatggc
    19681 tgttgcatag gattttcctc cttcttgttt ttacgtccct taattatatc atatttagca
    19741 agatgcctag aaagaacagc cttctgttgt tttgttttca tagcttatcc aactaatatt
    19801 gtgtatgata aagtaggtga gaaaaatgac ggataaacaa aagatagatg aatttttttg
    19861 gaataaaacg acgccagaag tggcacggga tttattgggg atgtatttgg agcatgacac
    19921 accagaagga agattagctg gatatattgt agacgcggaa gcatacctag gtccagaaga
    19981 cgaggccgcc catagctatg gtttaagaag aacaccgcgt gtgcgggcaa tgtatgaaaa
    20041 accaggtacg atctaccttt acacgatgca tactcatcgg attttgaaca tcattactca
    20101 gccagaaggg attcctcaag gagtaatgat acgtgcaatc gaacccgccg caatgattga
    20161 tcaaatgagt aaaaatcgtg gcggaaaaac tggtccagat atcagcaacg gtccgggaaa
    20221 attagtggaa gcattagcaa ttcctcaaga actttatggt cagtctatag cagatagttc
    20281 gttacgctta gtttttgaga aaaaaaagac accaaaaaag atcaatgctt tgcctagaat
    20341 cggtatccca aacaaaggtg tatggacaga aaagccgttg cgttttgttg tgtcgggaaa
    20401 tccttatatc tctttacaaa gaaaaaacca aatcgagaaa gattggggtt ggaggaaaga
    20461 aaatgaaaaa gaaggatcta ttaacatatt tagatgaaat aattgaaaaa caagtgacag
    20521 actatgatgt agctttagat tgggatacaa aaaatcatac gatcgagatc gttgttcgct
    20581 tgtttgcaga aaataaagca caatttgaga ttgatgatgc agaagggatc gtttcgcaag
    20641 aaccaattat cgaatttgaa gacggcgtac ttctttttaa tcctcagaaa tctgtttttg
    20701 atgaacgcaa ttatctagca gtaatccctt atgaaggaaa aaaagggttg gcaaaatcag
    20761 tagctgattc tttagtggaa tatctaaatg aagtattagc tcaagggcaa agcgatttgc
    20821 ttgatttttt ggatgaagac gatgacgaag ctgtattcga gcttcactgg gataatcagc
    20881 aactagcaga attagtagaa gtaaaacagc aaaatgaagc agatacttat ttaccgtacc
    20941 caagttatta aggagtgaca gatatgaaat ggaatgaagt aaaagtagaa actgaaagtg
    21001 aagcagtcga agcagttgct aatattttga tggaggcagg ggcgagtggt gtcgcgattg
    21061 aagattcttt agatgttgaa cattttcagt cggatcaata tggtgagatt ttagataaaa
    21121 atgattttac atcgctgaaa gaaggcgcac tagtcatggc ttattttccg gaaacgactt
    21181 tcttaccgga aatcttgcct tttatcaaag atcgtatcac acaattacct gagtttggtc
    21241 tagctattgg aaaaaataaa gtaacagtta gtgaagtaga ggaaagcaac tgggcaacag
    21301 cctggaagaa atactatcat ccggtgcgta ttacgcgaat gctgacggtt gcgccaagct
    21361 gggaaaacta ccagacagaa gatcctctag aaaaaattat cacactagat cctggtatgg
    21421 catttggcac aggcactcat cccacgactt ccttgacatt gacagcacta gaaacagtct
    21481 tgcgtggtgg tgaaacattg ctagatgtgg gaactgggtc gggcgtgcta agtattgcag
    21541 caaaatatct tggtgcaaaa gatgtctatg cctttgattt agacgaagta gccgttcgtt
    21601 cggcgaaaga aaatatggat atgaatgaaa tagccaaaga tgtccatgta tcagctaacg
    21661 atcttttgac aggaatcgag attgaaagtg atgtaatcgt tgcgaacatt ttagcagata
    21721 tcatcttatt gatgatccca gatgcttggc gtttactgaa gcaaacaggc acgctgatcg
    21781 tttcaggaat cattgaagag aagaagcaaa tggttctgga tgccatgtta gaacaagggt
    21841 ttatcgtgga tcaaattttc cagcaaaaag actggtatgc aattattttg aaaaaaccag
    21901 aggtggaata gatgcagcgg tattttttaa aagaatcata tgaatcaaaa gactattttg
    21961 ttttagaagg ggaaaactat caccacattg tacgggttat gaggatggaa cccgaggatg
    22021 aagttttttt ggcattcaat gatcaaatag ccattgttgc agaaatcacg gagattactg
    22081 aagaggctgt ttatctgaaa gaaattaaaa aagaagaaaa tcaaaaggaa ctgccaagtt
    22141 cgattaccat agcgagtggc tatcctaaag gggaaaagct ggattggatc gttcagaaat
    22201 ccactgaatt aggagcgcaa gcttttcttg gtttcccggc atcagcctct gtcgttaaat
    22261 gggatgcaaa aaaacgtatg aaacgacaac aacggcttga aaagattgct caagaggcag
    22321 cggaacaatc ccatcggcag atcgtgccat cagtagagtt attggaaacg aaacaagatt
    22381 tatttgagcg gctagatgat tatgacgtgg tcttggttgc ttatgaggaa tcagcaaagc
    22441 aaggcgaaaa atcaaatgca gccaaaattc ttagtgaaac aaaaccagat agtcgaatct
    22501 tagctgtctt tggaccagaa ggtggattat cccgcgatga agtcgattat tttgtagaac
    22561 acaaagggat actttgtgga ttaggaccaa gaatccttcg tacagaaaca gcacctcttt
    22621 atttattaag tgctgctagc tatcaatggg aattaatgaa tccttctttc agctaacgtt
    22681 cttcattaat aaaagagtat cgacagaaag aattgaaaaa atagtcaaca atttgtataa
    22741 tagaaacaat tatttataca atggatacga aaaatcgttt gaaaaagctt ttaaaaagcg
    22801 aacatttccg taaaaaaacg tataactgca cggattttgg gacaattatc aaacagatat
    22861 ttgtcccgat tcccgtttta ccgaaaaaag aaagggggat cgattcctgt gacaaaagaa
    22921 gaaattttaa cgggacccgg tgtcataaag ctcgttagtc aatacatggg tcccgaacat
    22981 gtagcatttg ttgagaaagc atgcgaatac gcgactgctg cacatgacgg acagtttaga
    23041 aaatcaggcg aaccctacat tattcatcct atccaagtcg caggtatatt agcagattta
    23101 aaaatggatc cccatacagt ggctacaggc ttcttacatg atgttgttga agatacagaa
    23161 atcactttag aagatctgag agaagaattt ggcgatgacg ttgctatgtt agtggacggc
    23221 gtaaccaaat tagggaaaat aaaatataaa tcccacgaag agcagctagc agaaaaccac
    23281 cgaaagatgc tgctagcaat ggctcaagat ttacgagtta tcatggtcaa attagctgat
    23341 agactacata acatgcgtac gttgaagcac ctgcgagaag ataagcaaag aaggatcgct
    23401 caggaaactt tagaaatcta tgcgcctctt gcacatcgtc tagggatcag ccggatcaaa
    23461 tgggaattag aagatacagc acttcgttat ctaaatccaa aacagtatta ccgtatcgtc
    23521 cacttgatgc agacgaagag agaagaacgt gaaaaatacg taagtggtac tgttgaagat
    23581 attcgaatag cgacagaaga gctggggatt tttgcagaaa tctatggacg gccaaaacac
    23641 atttattcaa tctatcgtaa aatgaaagat cagaaaaagc agttcaacga aatttatgac
    23701 ttgctagcta ttcgagtgat cgtagattca atcaaggatt gttatgctgt attaggagca
    23761 atccacacaa aatggaaacc aatgcccggc agatttaagg attatattgc catgccaaaa
    23821 gctaatatgt accaatcttt gcatactacc gtgatcggtc cggcaggaaa tccggtagaa
    23881 attcaaatcc gaacacagga aatgcatgaa atcgctgaat tcggggttgc tgcacactgg
    23941 gcctataaag aaggaaaaaa tgaaaaagta gaaccagatg gtatgacgaa acaattaagc
    24001 tggttccatg agatactcga acttcaagac gaaagctatg atgcttctga atttatggaa
    24061 ggcgtaaaag gagatatctt tagtgataaa gtctacgtct tcacaccaaa aggagacgtt
    24121 actgagttac caaaaggatc cggaccattg gactttgcat acagtatcca tacagatatc
    24181 ggtaacaaaa ccactggtgc aaaagtaaat ggcaaaatgg tgcagcttga ttacaaattg
    24241 aaaaacggag atatcattga gatcatgact tctccaaatt catttggccc aagtcgcgac
    24301 tggttgaaat tagttgctac tagcaaagca agaaataaga tcaaacgttt cttcaaagcc
    24361 caagatcgag aagaaaatgt gatcaaaggc cacgaatccg tggtcaaatg tattacagat
    24421 ctaggattta cgcctaaaga tattttgacg aagaacaaac tgcaagaagc actcgatcgt
    24481 tttaattatc aaacagaaga tgatctctat gcagctgtag ggtatggaga agttagcccc
    24541 ttgacgatgg ccaatcgtct gactgaaaaa gaacgtaaag aacaaaaaat cgagcagcaa
    24601 aagcaagaag cagaagaaat catgaatcag ccgaaaaaag aacctgacaa aatgaaagta
    24661 cgtcatgaag gtggcgttgt cattcaaggg gtagaaaact tactaattcg tatcagtcgc
    24721 tgctgtaatc cgattcctgg tgatgatatc gttggttata tcactaaagg cagagggata
    24781 tccattcatc gtcgagattg tccgaatgtt cagcctgaca aaccaaatgt agcagaacgt
    24841 ttgattgaag tcgaatggga agatacatcg aatacacgaa aagagtatga tgcagatttg
    24901 gaaatttacg gctataatcg ttcaggctta ttgaatgatg tacttcaaac agtcaatgcg
    24961 ctaacgaaaa atctcaacag cgttgaagca cggacgaata aagataaaat ggcgacgatc
    25021 catttgacgg ttggtatcca gaatttatcc cacctaaaga gtatcgtgga taaaatcaaa
    25081 gcagtacctg atgtctacag tgtacgccgg acgaatggat aggaggacag atatgagagc
    25141 agttgttcaa cgggtaagta aagctgctgt gtcagtcgat cagcaagaaa ttggaaaaat
    25201 tggctacggc ctacttgttt tattaggcat tcatgaaacc gatacgcaaa aagatgtgga
    25261 ctatctggta aaaaaaattg cacaaatgcg tatttttgaa gatgaacaag gaaaaatgaa
    25321 tattagtgta gaagatgtgg gaggacaaat tttaagtatc tctcaattca cactgtttgc
    25381 ggatacgaaa aaaggaaatc gaccaagctt tgtggaagcc gcacgaccag aaacagctat
    25441 tcctttatac gaatcattca atgaaggaat cagaagtcgc ggcatcacag tcgctaccgg
    25501 acaattcgga gcagatatgt cggtttctct cgtcaatgat ggacctgtaa cgatcattat
    25561 tgattctaaa aacaaataaa gtaatctggt tttcactagt aaaaactatg aaacacgtcg
    25621 cttaagttag actgataaac tctaacttaa gtggcttttt tgtctgcaaa aagcgcttct
    25681 tttgtcagca gtcggaaaaa aagttaagct taaattatac aagttatttt ttataggagg
    25741 ttgctgaaga tgaaagaagt accagtagta gatatcaaaa tcacagattt aaaaaaattg
    25801 tatcaaaaag gatacaacat gttggaggag ttacgccatg aagcggacgc tcccgtcgtc
    25861 aaagcaaaga ttttcaataa agaagctatc acgatctacg gatcatcagc agcaaaagta
    25921 ttttatgatc caaggaattt caaacgaaaa ggtgctatgc caaaattagt attgaagaca
    25981 ctttttggtc aaggtggagt acagactttg gatggagctg ctcatcacca tcggaaaaat
    26041 atttttatgg atctaatgac accggaaaga atggaagatt atcatcgtat cttagataag
    26101 aatctgacac aagcacttga agcacagcat ggtcaatttg aactatttga tttaagtaag
    26161 atggttttct ttacatctat ttgcgagtgg gcaggtatca atttatcagc gatttctaaa
    26221 gatgaggtcg aaaaattagc agaatatcaa atctctatga tcagcggaac gtttacttct
    26281 ccgattgatc acataaaagg tgtcgaaaat cgcaaaaaat cagaaaaatg ggcgcaaggc
    26341 ttgattgaag aagctcgaca aaatcctgtg gctggaaaag aaaatgtggc attatatgct
    26401 tttgccaatg ccacagattt agatggtcag cttttacctc tggaagtggc agctgttgaa
    26461 ttattgaaca tcatccgtcc aacggttgct ctaactgtgt gggcggcatt gatgggacat
    26521 gcacttttca gtagaccaga tttgtatcag caattaaaaa atgacttttc gacgttacaa
    26581 gatccgttta ttcaagaaat gagacgctat tatcctttct tcccaatgct acctgcgatt
    26641 tcgctgaaag aagtagaagt agatggttat cgtataccag aaggcagttg ggttatttta
    26701 gatttatatg gaacagacca tgatgaacga acagttgaag cgccagattc ctttatgatc
    26761 aaacggtatg tagggaaagc aaaagatatt tcctataaag aagaatatga gatgattgca
    26821 caaggcgggg gaaattttcg acaaatgcat cgctgtgcag gagaatggat cactcttcat
    26881 agtctacgtg tgttttccga tcagctagta aataagtttg agttctctgt acctgaacaa
    26941 gattggacga ttccattcaa tcagtttccg acttatccga atagccgagc gctactttac
    27001 aagaattaga ttagcataaa cttatcgaaa aaaaggaaga tcaaacagtg ctgatcttcc
    27061 ttttttcata ttactataaa ttgataaggt caattgatca aaatccacga aatgcttcat
    27121 caatggtttg ataatcttca ttggataaat gcaaatctaa agcttggaca ttgtcagata
    27181 cttgctctgg acgcttagct ccaggtataa ctacagacac tcgtggattc ttcatgtacc
    27241 aagctaaaac aagttgcgca ggagtggctt ggtatctttt agcaatgggg cgaagtacat
    27301 cgacagcggt taaaatttct ctgaaacgtt ctccttggaa atctggattt ctttttcgag
    27361 gatctccttc accaaattgt ttttcctcac caagttcata ttttcctgtc agcaaaccgg
    27421 aagcaagagg aaaataggga acaaaactga ttttgttttt ttcaagataa gggaataatt
    27481 ctttttcagc ctgccgatgg atcaaactgt atttatcttc tactacatcg acatatccat
    27541 ctgcattcgc ttctttcaat tgttctaacg tgaagtttga cacaccgact gctcggattt
    27601 ttcctgcttc ttttaattcg tgcaatgtag caactgattc attttttggt gtgctttcat
    27661 ccggaaagtg gatataaaaa atgtcgatgt aatcagtttg cagacgtttt agtgcatctt
    27721 ccaccgattg tttgagaaac tcaggagaat tatcaaatgt tcgcccttta tttggtacat
    27781 gagcagcttt tgtagcgatg acgacacgtg agcgatcata ttctttttcc ttcagtacct
    27841 cgccaatcag ttcttcggaa cggccgtttc cgtaagcata agcggtatcg atcaaattga
    27901 tcccgctatt caaagctgta cgaactactt gttttcctgt ctcatcttcc aaaccgtcaa
    27961 aaagattatg tcctccaacg gcatttgctc ctaatccaag ctgttctgcg tagacttgtg
    28021 aatgtccgat tcttatttct gccatagctg attcctcctt tttgtctagt ctaaaacaaa
    28081 ataccaaaaa gctgaactaa aacgtttttg tgaggggaaa tagtcagata tctcttgact
    28141 ttgagactgg tttttagtag gttataagta atatcgaatg tcaatgaaag agcgagtaag
    28201 tttttgaaac tttacaagag aggatcatcg aggctgaaaa tgatctaaag tttcattagc
    28261 ctaaagacac tctggagatg gacgagtgaa aagccgtccc gcgtacgagc gttattcgta
    28321 agaggaaaga gaaatctttc aaaattaggt ggtaccgtgt atgaatttca ttcacccttg
    28381 ttcatgatga acaagggtga tttttttatt tacatagcta agaaagggag agaaaactat
    28441 gagtttccaa agaccaaaag gaacaaatga tattttgcca ggcgaatcag aaaaatggca
    28501 gtttgtcgaa gaaacagcac gtttattatt cagagattat cagtataatg aaatgcgtac
    28561 accgattttt gaacactatg aagtgatatc ccgaagtgta ggggatacaa cggatatcgt
    28621 ttcaaaagag atgtatgatt tttatgacaa aggggaacgc catgtgacgc ttcgaccaga
    28681 aggtacagca ccaatcgttc gttcttttgt tgagcataaa ttgttcggcc cagagtatgc
    28741 gaaaccgttc aaaacttttt atatgggacc aatgtttcgc tacgaacgcc ctcaaaaagg
    28801 acggttacgt caattccatc aaatcggagt agaagcattt ggatcagaaa accctgcaac
    28861 tgatgtggag agcatggtga tggcacttga tttcttcaaa cagttgggga tcacgcaaat
    28921 ccggctagtc atcaattcat taggtgataa agaaacgcgt caagcctatc gtcaagcatt
    28981 gatcgactat cttttacctt ttgaatcaga gctgagtgaa gactctaaac gccgccttca
    29041 tgaaaatcca ttacgcgtat tggacagtaa agacaaacga gatcaaaaat ttgtggcaga
    29101 agctccatct atcttagatt atctaagcga gcctgctcaa aaacattttg ataccgttgt
    29161 ttccatgctg gatgcattgg ctgttcctta tgaaatcgac agtaatatgg ttcgcggact
    29221 agattattac acacatacga tttttgaaat catgagtgac gcaccaaaaa tgggggcaca
    29281 agcaacgatt tgcgcaggcg gacgttatga caatctagtg gaagaactag gtggtccttc
    29341 aacacctggc ttcggatttg caatgggtat cgagcgatta ctcttgacta tggaggcaga
    29401 ggaagtagtt atccctgcat ttaatgagtt ggatgcttac gtggtcgcac tcggagacga
    29461 aacaaatatc gaagcattga aagtggtcca agcgattcga aactttggtt tttcagctga
    29521 ccgcgacttc atgaaccgta aagcaaaagc gcaatttaag acagcagata aagcgaatgc
    29581 caaattagta ttggtgatcg gtgaagatga gcttgctagt caaacgatta atgtcaaagc
    29641 aatggcaagc cgaaaagaaa aaagttttcc attagaagag atatatgaac attttgatga
    29701 agtctatgat gaaatgactt tattcgagta ggaggaaaaa aataaatggc acaaagaacg
    29761 atctattgcg gattagtttc cgaacaacaa ttagaacaaa cagttacatt aaaaggatgg
    29821 gtacaaaaaa gacgagacct tgggggagta atctttatcg acctacgtga tcgtgaagga
    29881 atcgttcaaa tcgtctttaa tcctgaaatc aacaaagaag catgggaaat cgcggataaa
    29941 tgtcgcagtg aatacgtgat cgaagtgact ggggaagtta gaagacgcgg agaaaatgca
    30001 gtaaatccta aaatggccac tggtgaattc gaagtgattg caagtgaaat cgtgattttg
    30061 aatcaagcaa aaaccccgcc atttcaaatt gaagatgatc aagcaatcag tgacgaaata
    30121 cgtttgaaat atcgttattt ggatctgcgt cgtccaaaaa tgactaaaaa catcaaatta
    30181 agaaatgcga caacaaaagc gattcgtcat tatttagatg ataatgactt tctcgatatc
    30241 gaaacacctt acctagggaa atctacacca gaaggcgcaa gagactacct agttccttca
    30301 cgtgtccatg ctggacattt ctatgcgttg ccgcaatctc ctcaattgtt taaacaattg
    30361 ctgatgaatg ctggattcga ccgttattat caaatcgttc gttgtttccg cgatgaagat
    30421 ttacgtggag accgtcagcc tgaatttacg caagtagata ttgaaacaac gttcttaaca
    30481 gcagaagaaa tccaaactta cacagaggga ttgattgcga aggtaatgaa agaagttcgc
    30541 ggtatcgaag tcacattgcc atttcctcgt atgacctatg atgaagcaat ggctcgctac
    30601 ggcagcgaca aaccggatac acgttttgat atggaattga tcgatctaag cgatacagtc
    30661 aaagaagtag aattcaaagt cttccaaatg gctcttgaaa acggcggtgt cgtgaaagca
    30721 ttgaatgcta aaggcgctgc agatcgctac tcacgaaaag acatggatca gttaggtcaa
    30781 tatgtaggac aattcggagc taaggggctt gcatggctga aagtagaaga agacggattg
    30841 aaaggtccaa ttgctaaatt catgggagaa gcaacagaag caatcattaa agcaacagat
    30901 gcaaaaccag gtgacttgct gatgtttggc gcagataaaa gtgaaatcgt cgctgctgca
    30961 ttaggtgcta tccggacacg tttaggaaaa gaattaggac taattgatga atcgaaattc
    31021 aatttcttat gggtaactga ttggccacaa tttgaatttt cagaagaaga aggtcgatat
    31081 gtctctgctc accatccatt cacgatgcca aaagaagaag atatcccgtt attggctgaa
    31141 gaccctgcaa aagtctatgc agaagcttat gatatcgtct tgaacggtta tgaattaggc
    31201 ggaggttcta tccgtattca tactcgtgag cttcaagaaa aagtactaga aactctaggc
    31261 tttacaaaag aacaaatgga agaacaattt ggtttcttgt taacagcttt agattacgga
    31321 ttccctccac atggcggtat tgcattagga ttggaccgtt ttgcaatgtt attagccgga
    31381 gaagataata ttcgtgaagt cattgccttt cctaaaaacg gaaaagcagc agatgtgatg
    31441 agtgatgcac caagtatggt ttcgccttta caattgttcg aattgaatat tgatgtaacg
    31501 aatatagaag aatagccgat aaaaaggtaa aaaggatttg tcgaatacgc ttcttttgac
    31561 aaccttgatt taattgaaaa acactttata atgaagccat aacatataaa gcggggcttt
    31621 tccatgaaaa aaacattcga aaattgggct tatcatgatt acacgaccaa gctttcggta
    31681 tctatcgttt atgcgttgat cgcatcagtc gcattgaatt tcttttatca gccaggacat
    31741 atttattcaa gtggtattac tggtctagct cagattttga cgactttgtc aaaatcactg
    31801 ataggattcg aagtaccggt atcaacaact ttgtatttac tgaatatacc tttgtttgta
    31861 ttggcgtggt taaaaatcgg gaagaagttt acaattttca cttttatcac agtcactttg
    31921 acctcccttt gtatccatat tttaccggaa acagtcctat ctaccgatcc aatcatctgt
    31981 gcgttgtttg ggggggctgt gatgggacta ggtattgggc tagcgttgag aaacggccta
    32041 tcatcgggcg gtctagatat cgtgagtatc acgattcgta aaaaaacagg aaagtcgatt
    32101 ggttctattt cgatctactt caatgcattg atcgtttttg ttgccggaat tctatttggc
    32161 tggcaatata tgttttacag tacgttgtct attttcgtca gtggaaaagt aactgatgtc
    32221 gtttatacta aacaaaagaa gatgcaggta atgatcgtaa cgaaacatcc agaaaaagta
    32281 gtaaatgaaa tccaaaactg tatgcgtaga gggatcacga tcatcaatga agcagaaggt
    32341 gcttataagc atgataagca gacagtattg atgacgatcg ttacacgata cgaactgcct
    32401 ctacttagag aagcaatgaa agcttctgat ccacaagctt ttgtaagtat tgcagaaaac
    32461 gtccagatac ttggtcgttt ctatgaggat ggcatttaga tcgagtttga caaaaattca
    32521 tgaaatactg ctgtagacag acgttcgttt gtctgcagtt tttttctacc atagtagaat
    32581 cagcaaagaa aaactgcttt tttatttgaa attttcttaa agttgaaaaa aagcatgttt
    32641 atttttttaa atttatggga tgatagaaaa aaatagtaga gaaaggacac gattctactt
    32701 gctattttca cttaataccc gtatattacg aatgaaaaaa gtttatgaaa agttggaata
    32761 ttgaatggaa aaacaaaaaa ggttaaaaaa cagccgctac atcactgggt ttgatgggct
    32821 ccgttcatta gctgtggtgg gtgttatctt ctatcacctt ctgccaacta gtatgaaagg
    32881 cggctatttg ggcgttccga tttttttcgt cgtatctggt tatttgatca cggatctgct
    32941 gcggcaggaa tgggaacaaa atggaaaaat caatatttgg caattttatg tcagaagaat
    33001 gaagagactc tatccggcac ttgtttttat gcttgtgaca gcttcggctt atatcacttt
    33061 gtttcagcga gggctgttaa acaatcttcg aggagttgtg gtcagcagct tactgtatgt
    33121 caacaactgg tggcaaatca ataacggttt atcttatttc gatcgatttg ctaatgagtc
    33181 accgtttacg catatctggt ctttagcagt agaaggtcaa aactatttgg tttggccgat
    33241 cttgtttgta ttgttgatgg tatttgttcg taaaagaaaa tggatctttt atactgtgtt
    33301 aggtacatcc ttcctctccg ccatcttgat gatgatcttg tatacaccag gaggcgatcc
    33361 aacccgtgtt tattacggta ccgacactcg tctgttttct atatggttgg gaagtgcgct
    33421 tgcgtttgtt tggccaagta cgcgtttaaa gaaaaacatc ccgaaacaag cgaaaaatat
    33481 tctgaatatc gctggaggaa tctcgctttt ggcactgatt ctttgcttct tctttttaga
    33541 tgatcattac aatttcatct attacggagg aatgctccta gtgagtctgt tatgcgtagt
    33601 gctagttgca gtgacagcac accccggagc aagtttgaat cgatggctga caaatccagt
    33661 atttacttgg attggcaaac gaagctatgg catttatctg tatcagtttc cagttatgat
    33721 tttttatgaa gcaaaggtga ctgatattgc cgatcatgtt ttgttgcata ctttagtgga
    33781 aatcacattg attctaatca tcagtgaact ttcttatcga tatgtggagc gtccgctagc
    33841 acgttttgat tatggtcgta cattccaagt gatgaaagga tggttcagca aaccgatcat
    33901 cagtaagagc aaaccatggg ttgttccagg cacattactt gtagcaattg cactcgttgg
    33961 tttcgttacg gcaccgaaaa acgctgtaac agccgatcaa aaacaactgc aggcaaaaat
    34021 cgctgaaagt aaaaaattag cagaagaaac cagaaacaat tcagaaaaca ccactagttc
    34081 ggttgaccaa gcgatccttg ataagtacga gttgtccaag gcacaaggga ataaggcaca
    34141 aaaattagaa ctaacggcat ttggtgattc agttatgttg gatgctgcaa cggatctaca
    34201 agaactttat ccaaaagtag tggtagatgg agatgtcgga cgacaattat atgccagtgt
    34261 accgtacatt gaaaaattaa aggaacaaga tttgttgaaa gacactgttc tgattggact
    34321 aggaacgaat ggctcattct cggaagctca gtttgatagt gtgatggatg caatcggtga
    34381 tcgaaaagta tactgggtca atgtccgagt accgacgaag cgctggcaaa atgacgtgaa
    34441 tgcgatgctt gaacagatga cgaaaaaata cgacaatatg acgctgattg attggtacag
    34501 ctacagtaat gaccatagtg actggtttta tgatgatcaa gtccatccaa atcctgaagg
    34561 gatgacacat tacattcact tagtcagcga agccttgcta ggaggaagtt caagtacgaa
    34621 cagcagtgag acaaacgtga cagaatgata gctacaaaaa acttcaggca aaaacatttg
    34681 tttttgcctg aagttttttt atatttaccg tgtttttaac attcatatag attcaggaag
    34741 caaaacggtt gagtgtgtct gtaaataacg ttctttttgt tttcgggtga gttttttgaa
    34801 tgcagcttct gcttttgttg cttcgcttct tgaagaaaat acttctgcat ggatcatctt
    34861 aacaggtctt cttttttgaa gacgagtata tttagcacca gtaccattgt tatgttcctc
    34921 taatcgtcta gaaagatcgg ttgtatatcc accataaaat gtctgatctt tacagaataa
    34981 tacgtaaaaa taatgttcat ttgccataga gcatctcacg aatctctgca gtgtattctc
    35041 catccatatt gtaagtgatc aatggtggag cgactttgaa tccgtctaat ttgccttctt
    35101 tgattccttc aactaacaaa atatttgcct cttttccagg ttttgggtaa acaaattgga
    35161 tccttttagg tgcaattcga tagtcttcca tgacctgaat gatttctaag aaccgatcag
    35221 gacgatggac catagtaaag cgtccatttg tttttagtag cttacttgaa atatcgatca
    35281 cttcttctaa cgtcgtatga atctcatgac gggcgattgc caggtgttta ttagggttcg
    35341 ttttatttgt tggcagccct ttgaaataag gtggattaca gacgactaag tcacaagaat
    35401 tatgtcgaac gacagataag ctgtctttca gatcgatggt gtggacagtc atttgttcat
    35461 ttaaatggtt aagcgcgata ctacgtcttg ccatgtctgc tagacgaggt tgaagttcga
    35521 tagcgtcgat agccgcctgg gttcgtttac ttaaaaaaag tccaactgcg ccatttcctg
    35581 cacaaaggtc aacaatcttc ccttttttag gtacacggga aaagtgagca agcagcacag
    35641 catctaaaga aaaagaaaac actttggaac tttggataat cttgatatct tctgcgtata
    35701 attggtcgat tcgttcgtct tcgtgaagca tggattccct ccaaaatgaa aaaaatagtc
    35761 gtctgtatta tactattttt attaaaaaga accaaggtgg cttgtcaaac ctctattttt
    35821 tatgcatact atgaccataa gaagggaaag gaagagacta tgttttatcg atttatgcgc
    35881 ggggtagttc gagtactatt agccttagtt aatggaaatg cccgctatga gaataaagaa
    35941 gttttaccgc aagatgagaa ttacatacta gttgctcccc atcgtacttg gtgggaccca
    36001 ttatatctgg cggtagctgc agcacccaag gaattcagct ttatggcaaa agaagaactg
    36061 ttcaaaaatc cagttctgcg atttatatta actcgatcca atgcttttcc agttaaaaga
    36121 gaaaatccag gaccaagcgt cattaaaaca cctgtaaaga ttttgaaatc gacaaatttg
    36181 agtttgatca tgtttcccag tgggacaaga catgctacag aacttaaagg cggaatggca
    36241 ttgatttcca gaatgtctaa agcgaaaatc gtgccagctg tatatcaagg tccgttgaca
    36301 cttggggatc tgttcaagcg tcagagagtg acagtgcgtt tcggcgaacc aatcgactta
    36361 tcagatatca agaaaacgga taaagaaggt atggcggaga tcgaacgacg aacacaagca
    36421 gcttttgaca aattggacaa agaagtgaac cctgatttca aatatgaagt caaaaaaaaa
    36481 taaaatgata agtttatgcg tgggcggtct tttgaatcta ctgtcctgtt cagttcagac
    36541 tttttcaatg aaaacgaggg agagacgtca agtctgccct ctttttgcgt tccaatatgt
    36601 aaaatagaag acaggtgtca tgtaatggat caaagtgtta taataattag aaggacattt
    36661 tttgaggtga ttgaatgcgt tttttacata cagccgattg gcatatcgga aaaaaactac
    36721 aaggttatga cttgattgaa gaccagcgtc atgtactatc ttctatacta gatatcgcga
    36781 aagaagaaaa agtagaggca atcgtgattg ccggagactt atatgatagg agtgtcccag
    36841 ctgttgatgc cgtagaatta tacaatgaat tgatggtcga ttggaattta aaggaaaaga
    36901 tcccgatttt tgctatatca ggaaatcacg atagcagtac gagactttca gcgggtacgc
    36961 catggttcag ttattcgaac tattttttgc gaacacagct agcagaagca tttgaaccag
    37021 tcgagtttaa aaacgtacaa tttttctttc ttccttactt tgaaccaatt gcagcgagat
    37081 tatattttga agatgacaat atccgaacga tcaagcaagc ggtagccaag gtgatagata
    37141 aaatgcagga gctatttgat tcagaaaaaa aacaagtatt gattagccat ttttttgtaa
    37201 tgggaagtgt aaaatctgat tcggaaacga aaatcgaagt aggcgggttg gattcgatcc
    37261 ctggtgaact acttacaccg tttgattatg tagcactagg acatttgcat aatcaagctg
    37321 ctttgagaca ggataatgct cgctatagcg gttccccatt gaaattctct ttatctgaga
    37381 tcaaccaaaa aaaaggcgta tggatcgttg acctgacaac aggcctggag ttgaatttta
    37441 gggagatcga acccctgcat gatattgaag aaataacagc gagtttcaaa gaattgctgg
    37501 atcctgcctt ttatcagtcc gtcaatcggg agaattacat ctatatctat ctcactgata
    37561 gaacgatcat cccgaatatg atgaaccagc ttcggcaaat atatcctcgt attttgggga
    37621 ttgaacgggc aaacggtcga gcagaacaaa caaagcgcaa acgaaaagta ctagaaatga
    37681 aagatcctca aaaattagca gaagcatttt ttagtgaaat gacggaagag cagctaactg
    37741 caaaccaaga aaaatggctc ggagaaacgt tgcaagaaat catggaaatg gaatgatcaa
    37801 gaatgaaacc gaaaaaatta caacttaaaa attttggtcc ttttatcaat gagaccgtag
    37861 atttttcacg tttgacagaa gcaccgcttt ttttgatcag cgggaagaca ggagctggca
    37921 aaacgacgat ttttgatggg atcaccttcg cactttttgg tgaaacttcc ggaagacttc
    37981 gctctggaaa agagatgcgt tctttgtttg ctacaccaga cgaagaaaca agcgtgactt
    38041 tttcttttga acatcagcag atgagctatg aaatcgaacg aaaaccagaa caagttttag
    38101 caaaacgaaa aggaaacgga acaaaaaaac aggcagccaa agtaacgttg accatttttg
    38161 atgggaaagg aaaagaaata aaacaaatca caaaacgtac agaagcagat cagttgatca
    38221 gagaactgat gaatctcgat gcgaaacagt tttctcaaat cgttttacta ccccaaggag
    38281 aattccgtaa ttttttggtt tcatcaagca gtgataaaga gactgtttta cgtcatttat
    38341 tcggtactca atttttccaa cagttcaatg agcgattaaa agaaaaagca aaacaacagc
    38401 aacaaaaatt ggatcattta gagcaagagc tgcatcttct gcaaaaaagg tttgttttag
    38461 tcaaagaaga ggaaccagca gcagggtttg aagccgtttt agcccaatgg acaaaccatc
    38521 aggcaatact cgaaaaacaa atcacggaag aaaaagaagc tctaacggaa cttcaggaaa
    38581 aacaaaagca actagaaaat tcctactatc gttttgaaag cttgaaaaaa agttatgaag
    38641 aaaaaacgat attaataaac aagcaaaagg aattagctgc tcaaaaagac gaaatagagg
    38701 aaaagaaacg atggattggg tattatgaat ttacgcaacg attagtcgaa ccaatccagc
    38761 gcctacaaga aataaaagtt gaaaaaatag aactgtcaca aaaaagtagt gagcaaacaa
    38821 agaaactagc gatgactacg cagaattatg aagagtggca aaaaaatgaa gcaaaccgcg
    38881 tacgccgaca aacaaaaatc aaagaagctg ctcaaaaact gcaaaacaaa cagatgatgg
    38941 tgccaattgt cgaatcctta cgtagtaaaa aacaagacgc agaacaatta acaatttcat
    39001 tggataaaga agaattgaat gccgagaagc tgtatcaaaa tctcgctatc tatcaggaaa
    39061 gaactcgaat tcttcaagaa aatttactgg atcaggaaaa actgcaagaa gatcgtcttg
    39121 cttttggaca gttaaaatat ctagatgaaa agcagcaaga aatagaaaaa caaaaagcaa
    39181 aagacactgg gtcgctcgca cagataagag aagaactcaa aaaagcaact gaagaaataa
    39241 caaaaaatag tcagctattg aaagaacaga cagaacaagc agaacagctg aaaagccaat
    39301 gggcaaagca gcaaattgct cgtcttcagc tttttttgcg tccaggggag ccatgtcttg
    39361 tttgtggatc aacggaacac cccatacaac aattaaaaca cgaacagcca aataaggaag
    39421 atatcttaaa agtagaacaa caactggcag aagctgagtc tgctgtagaa agaactcagc
    39481 aaatcattgc caaaagtgaa gcacatgaaa ataatcttca acaacaatta tcagatttag
    39541 aacaaaaaat catggcaacg aatatacaat tggctgaaca agaagaacac ttgcaacagg
    39601 ctttgaaaaa ggcatttcct gagataacag aacaaaaaac aaaaacaact cttgtagtaa
    39661 tcgaacaatc tttagataga cgaaaaagca agatggccaa tgcaagaata gagctggaag
    39721 aaataagaca acaagcagaa aagctcgaac aacaattagc tgtctacaaa cagcagcaga
    39781 cagaaaaaaa taatcagctc cagcaactgc aaggagaaat caaaagttta gaacaacaat
    39841 tgcaagatac ggatagtaac tgtttagaag aggagatacg acgacttgaa aaacagttag
    39901 aagaagactc gaatcaacta gctgttgagc agaaagcagg agtgcaattg ttgcaagatc
    39961 ttcatacgct tcggacacag cttgatcttc aacatgaaca aatagaaaaa atagatgaaa
    40021 aaatagaaaa ggaacaagaa agaatagcta aaaagttaga aagccagtcg tatttttcaa
    40081 caattgaaga aatctgtgca tttgcacaac agcaagcaca atataaagaa aaccaacgta
    40141 cagttacttc ttatcatgaa gagcaattag tgacagctga ccggctgcgt caattagaaa
    40201 atatccagct aactgagaca ttcccagata cagaagagat cagccaacag ttagaagaaa
    40261 taagacgtat gatcgaaata aagcaagaaa agatatacgg tttacaagaa caaaaaatta
    40321 gtaatcaaaa aatctacgat gaatgtcttt cgatttatca cacaagccag acgaaattag
    40381 atgagcttac gcaattacag cagctttcgc aaacattcaa cggagaaaat cctaagaaga
    40441 ctagtttgga acggtatgtg cttcaggttt atcttcaaga agtgttacaa gtagcaaatg
    40501 atcatctcca acgtttaacg aaaaatcgtt atcaatttga gctagcggat accattggca
    40561 gttatcgagg gaaaaccgga ttagaaatca atatctatga tgatcaggca ggtatgtctc
    40621 gaagtgcgca taccctgtct ggcggtgaga gttttattgc agcactttct ttagcattag
    40681 ctcttgccga tgtgatccag acacaagctg gtggtgtagc aatcgatgca ttgtttattg
    40741 atgaaggatt tgggtcatta gatgaagaag ctttggaaat ggcaatggaa gctttagaaa
    40801 cgatcgaaag tgaaggaaga atgatcggca tcattagtca tgtaagagaa ttgaaagaac
    40861 gagtattaca acaaataaga attgatacag aaggtagcgg acaaagcaaa atacgctatc
    40921 aacttggata aaaagggaga ttggtaacta tgaaatggag tattccagaa aaagtcattg
    40981 cacgtggacg tcaatacttg caagaaggcc gagtgttatc ggttgtccct gaccaagaag
    41041 aaaacgtgtg gcatgcagaa gtcttgggca gtgaattgta tatggttgat ttggatggta
    41101 cagcaaaaga gatagattac tgccaatgtc cctattggga ggaacataaa tattgtaagc
    41161 atacagttgc tgtggaactt tatttacggt cgaaaaatct atctcgtatc atgaaaaaag
    41221 accagccaat gctagaaccg gtaaaagcaa caagtgaggg agaaatcatt gcaaaaggtt
    41281 tttctcgtct aaaaacacaa aacaatcctc aagcggtgca acctttgatt attgaatacc
    41341 aagtagaaac gattgagact aatcagtatc acccagagct ttctattttg gcactttact
    41401 tgcgtatcgg ttcattggca tcaccgaaaa aaacatatat cgtaaaaaac atctatgatt
    41461 ttttacaagc ttacacagaa aaagaaactt acactgttaa taaacagtac cagtttcgtc
    41521 tagataaacg ggcgtttcaa aaagaagatc aaaaaatact cacgcatctt gcaggaagtg
    41581 ctcagacgca tcaattatta ggtacgaacg gcttacaagt caaaggaaaa ctagataaaa
    41641 gatatctgct tctcccagta gaacaagccc gcttcctgtt agagcagatg aatcagacta
    41701 cacgtttgca tctgcagata aatgaacaaa acgatcaagg aatacaattt tccgatcaaa
    41761 acaaaccttt atcattcaaa gtggaaaaat ttggagaaga ttatttgctg caagcattga
    41821 atgattttga ttttttcttt atgcattatc agtggggagt tatccaaggg acattttatt
    41881 ctctgacgaa atatcaacaa acggtttatc aaacttggaa acaattgatt cgccgattgg
    41941 agaaaccaga agtagtgttc aagaaaaaag aattaccgtc tttgtttaaa gagattatcc
    42001 ctctgctgtc agagatcggc gacgtagcta ttgcccctgc agtagaagag gaagtagcag
    42061 atatccccgt cgaatttatt ttctttttcc gaaaagcaaa aggaaaaatc caagctcgag
    42121 tcgatttcgt ctatggtgaa gtcatctatt cgactgaccc gaagcatgag gtctcgacag
    42181 aacaggcttt tcaggtgtta cgtgacacag tagaagagaa acgagtactt gatctattca
    42241 gaatgtatcg ctaccagaaa aatgaaactg gttatgaacg tccattgcca agcggggaag
    42301 aactatatgc ctttttccgc acagaactat ctgtcttccg tcagtttggt gaagtcagac
    42361 ttggaagaaa attgcgagag ttgtatttag atgcgcataa acatcaaccg aaaatcgaag
    42421 taaccgagac cggttcatgg ctcgatattc gattcgatgt gacagggata gaggagcaag
    42481 aaatcgatca tgtcctgcaa agcttgctga gaaatgatgc tttttataca ttagaaaatg
    42541 gtcaggttct ttcttttgat tcagaagaat ttcaacaaac aagccaagtg ttgcaacaat
    42601 tacgggaatc gatacgtaca gaagaaggaa cgatccatgt acctaaaaat caaggattga
    42661 tcattcaaaa tcaattggaa aaaagcaatg ctacttttag tgaatcgttc caaacgatgg
    42721 tacaagatct cattcatcca gaaagatacc aggcacagct tcccaaagga ttgaatgcaa
    42781 cgatgagaga ttatcaaaag caaggttttc gatggttgaa gatgttaggt cattatcagt
    42841 ttggcggtat tttagccgat gaaatgggac ttgggaaaac actacagaca attgcctttt
    42901 tactttcgga aaaagaagaa cggaaaagct tctctgcttt gatcgtagcg cctgcgagct
    42961 taatttacaa ctggcaggca gaggtgagaa aattcgcccc ttctttaagt atccaagtaa
    43021 tcaatgggaa taaaaaagaa cgtgaagaat tactggctaa agacacagat atccgagtga
    43081 cttcttatgc cagcttaaga caggatctag ctaattatca gtcgcaaaaa attgattatt
    43141 tgattcttga tgaggcacaa atggtcaaaa atagcagtac gaaaactgca caagcattga
    43201 gagaattagc tgtacctcag cggtttgcac tgagtgggac accaatcgag aataatttag
    43261 aagaattgtg gtcattgttt gcaacgatta tgccaggatt tttcccgact aaaacaaaat
    43321 tcagggaact tgccgcagaa gaaattgcgc aaatgattcg accgtttatt ttacggcgag
    43381 ataaacaaac tgtgttgaaa gacttgccgg aaaaaacaga gatgaatcta tattctgcac
    43441 ttacagaaga acaaaaaact gtttatttag cttacttgcg tcaaatgcgt gaagaaatca
    43501 catcaatgga ttctgaagca ttcaagaaaa accggatcgg gatacttgct ggtctgacaa
    43561 gactgcgaca aatttgctgc gatcctcgtc tgtttattga agattaccaa ggcggttccg
    43621 gcaagctcga acaagtaaaa gatctactgg tagctgccaa agagaacaaa cgaagagttt
    43681 tgctgttttc tcaatttaca gggatgctga ctatcttgca agaagagtta gccgagctag
    43741 ggatctcgac attttattta agaggcagta cgaaaccaca agatcggtta agtatggtag
    43801 acgcatttaa tgctggcgaa aaagatgttt ttctgatttc cttaaaggct gggggaactg
    43861 gattgaatct cacgggagca gatacggtca tcttgtatga cctttggtgg aatcctgcca
    43921 ttgaagaaca agctgctgga cgtgcacatc ggatcggaca aaaaaatgtg gtagaagtgt
    43981 ggcgtatgat ctctgaagga acgattgagg aacgcatgga ttcactccag caagaaaaac
    44041 gcgaactgtt ccaaaaagtg atccaaggta atgaagaaca gttgacgaaa ctgactgaag
    44101 aagacatccg catgatttta agtgtaggag aaatcgagga gtaagagact cgaaaaagcg
    44161 ttcagtaatg ggtaagaaag cctttctaaa gaagcgattg tttatttgat ttaaaaaata
    44221 gcaaggaggc tgggattcca ttttatccca gcttccttgc tatcattttt ttatttctat
    44281 ttttaaaggt tatacaaaga ttgtcttcat tgtctctaac agctgatcaa aagaagaaat
    44341 ctcgatatcg caaattggag tctgttcaat tttgcgttct cgatggttga accaaagcgc
    44401 ttgccagtta gcactttttg cacctagaac atcattgtcg taattatcgc caacgtataa
    44461 ggtctcttct ggaagcatat gaaattcttt ctcagccagc tgaaaaatct ctttttctgg
    44521 tttttggaaa cctgttgctt gagaaatgag catattgcgg gaaggaatcc aattgttcaa
    44581 ttgaagttgc ttcagttttt ttgtctgatg gtcagtcggc ccatttgtga taattcctaa
    44641 tgggacattc ttttccttca agaaatcgag ggtttttttg acctcctcat gcaagcagat
    44701 attatcaagt tcttcctcgt aaattttttg aaataagagg ccatcttctt ccgtaatatg
    44761 agggtagtct aaatctttta gtgattggct gatccgatgt gctcgcatat attctagtgt
    44821 ccaatctcct gccattactt ttgggaagtt ttcatcacta tgatggcgga accggatata
    44881 tagtggatgc atatctgcat ctgaaacaag cggaacgact cttttgaccg cgtttcgaaa
    44941 tggctgctgc tgatcataca tcgtatcatc aacatcaaac acaactgatt taatcaaaat
    45001 tttacacgcc tttcggtttt cattgatttt ttcacaaatc cttgactatt gtaacagaaa
    45061 aaattgtcta aaaaagctga taaataaagg tttttcttac tatatttcta tttccttgac
    45121 agaataaggt ttttatattt cagttttttt cactaaaaat cgtgaaacac gtcaataagt
    45181 ttgatgaaca aattaatcat tatggtagaa gtcgattgat ttattttaat gcaatctctg
    45241 tggaattttc gaaagattta tttttttaat acagtctcaa tataactatt caaacataaa
    45301 ataacgttat ttgatttatt tgtttatagt aaattttatt tagtaatcat tgctttaaaa
    45361 tactacgctt atataacaga gaaaataagc gttataataa agaacagtat tatttaaaat
    45421 gacagaaaac attactatta aa
//
LOCUS       DADLIO010000015        44881 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.015, whole genome shotgun sequence.
ACCESSION   DADLIO010000015 DADLIO010000000
VERSION     DADLIO010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44881
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.015"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            212..604
                     /locus_tag="JOX41_000967"
     CDS             212..604
                     /locus_tag="JOX41_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAY6448728.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="JOX41_000968"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="JOX41_000968"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HAY6448729.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3165..4775
                     /locus_tag="JOX41_000969"
     CDS             3165..4775
                     /locus_tag="JOX41_000969"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HAY6448730.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5067..5936
                     /locus_tag="JOX41_000970"
     CDS             5067..5936
                     /locus_tag="JOX41_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HAY6448731.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="JOX41_000971"
     CDS             6101..7372
                     /locus_tag="JOX41_000971"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HAY6448732.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /locus_tag="JOX41_000972"
     CDS             7369..8664
                     /locus_tag="JOX41_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HAY6448733.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="JOX41_000973"
     CDS             8763..9026
                     /locus_tag="JOX41_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HAY6448734.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="JOX41_000974"
     CDS             9471..9920
                     /locus_tag="JOX41_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAY6448735.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="JOX41_000975"
     CDS             9977..11395
                     /locus_tag="JOX41_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAY6448736.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="JOX41_000976"
     CDS             11395..12255
                     /locus_tag="JOX41_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HAY6448737.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="JOX41_000977"
     CDS             12429..13202
                     /locus_tag="JOX41_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAY6448738.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="JOX41_000978"
     CDS             13349..13714
                     /locus_tag="JOX41_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HAY6448739.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="JOX41_000979"
     CDS             complement(13862..15070)
                     /locus_tag="JOX41_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAY6448740.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="JOX41_000980"
     CDS             complement(15089..15367)
                     /locus_tag="JOX41_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448741.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15560..16216
                     /locus_tag="JOX41_000981"
     CDS             15560..16216
                     /locus_tag="JOX41_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAY6448742.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            complement(16658..17455)
                     /locus_tag="JOX41_000982"
     CDS             complement(16658..17455)
                     /locus_tag="JOX41_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HAY6448743.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="JOX41_000983"
     CDS             complement(17452..18636)
                     /locus_tag="JOX41_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HAY6448744.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="JOX41_000984"
     CDS             complement(18661..19908)
                     /locus_tag="JOX41_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virion core protein"
                     /protein_id="HAY6448745.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="JOX41_000985"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="JOX41_000985"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HAY6448746.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="JOX41_000986"
     CDS             21888..22202
                     /locus_tag="JOX41_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HAY6448747.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="JOX41_000987"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="JOX41_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HAY6448748.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /locus_tag="JOX41_000988"
     CDS             22887..23531
                     /locus_tag="JOX41_000988"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HAY6448749.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="JOX41_000989"
     CDS             23546..23875
                     /locus_tag="JOX41_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448750.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="JOX41_000990"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="JOX41_000990"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HAY6448751.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="JOX41_000991"
     CDS             24863..25687
                     /locus_tag="JOX41_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HAY6448752.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="JOX41_000992"
     CDS             25680..26027
                     /locus_tag="JOX41_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HAY6448753.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="JOX41_000993"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="JOX41_000993"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HAY6448754.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="JOX41_000994"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="JOX41_000994"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HAY6448755.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="JOX41_000995"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="JOX41_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HAY6448756.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="JOX41_000996"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="JOX41_000996"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HAY6448757.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31684..32451
                     /locus_tag="JOX41_000997"
     CDS             31684..32451
                     /locus_tag="JOX41_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6448758.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="JOX41_000998"
     CDS             32441..34483
                     /locus_tag="JOX41_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAY6448759.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34764..34913
                     /locus_tag="JOX41_000999"
     CDS             34764..34913
                     /locus_tag="JOX41_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HAY6448760.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34924..36438
                     /gene="dltA"
                     /locus_tag="JOX41_001000"
     CDS             34924..36438
                     /gene="dltA"
                     /locus_tag="JOX41_001000"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HAY6448761.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36435..37640
                     /gene="dltB"
                     /locus_tag="JOX41_001001"
     CDS             36435..37640
                     /gene="dltB"
                     /locus_tag="JOX41_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HAY6448762.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37685..37918
                     /gene="dltC"
                     /locus_tag="JOX41_001002"
     CDS             37685..37918
                     /gene="dltC"
                     /locus_tag="JOX41_001002"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HAY6448763.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWCTPNKIIQQATALKG"
     gene            37921..39189
                     /gene="dltD"
                     /locus_tag="JOX41_001003"
     CDS             37921..39189
                     /gene="dltD"
                     /locus_tag="JOX41_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HAY6448764.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39330..40412
                     /locus_tag="JOX41_001004"
     CDS             39330..40412
                     /locus_tag="JOX41_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HAY6448765.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40412..41215
                     /locus_tag="JOX41_001005"
     CDS             40412..41215
                     /locus_tag="JOX41_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HAY6448766.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41285..42025
                     /locus_tag="JOX41_001006"
     CDS             41285..42025
                     /locus_tag="JOX41_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAY6448767.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42036..43040
                     /locus_tag="JOX41_001007"
     CDS             42036..43040
                     /locus_tag="JOX41_001007"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HAY6448768.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43085..44848)
                     /locus_tag="JOX41_001008"
     CDS             complement(43085..44848)
                     /locus_tag="JOX41_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448769.1"
                     /translation="MLFLTGIAYFFYFIFSPADSNQMKEIKDSWVFYTKDDPDFKFDS
                     KYTRTIPTVDKDETFIMETTLEKPLDEANLLIKGNHQWITVYLGEKILYQRKDYQEES
                     NPGLSLAVIDLPANYIGKKLTLTVSSPYQNYAGLPPKVYLGTTGPLISFIYSQSVPQV
                     LTMIIAVFIAIGTFFYTIYLMYKQKRLEYSLILLSCFALALGFEAVSEDILSGILFEP
                     FVHSFLSHLFIILTSAFIICYYWSRMFYYKKWYGIFCTFQLLIFIGVLLYATFTPAEL
                     PELMPIANIASVISTLVTSLACIGEAYKNNRFYVACTPWIVLVAIIHCLIYIQTALGI
                     YQTTINWSTILYIIILIVIISYNLIDHILNTDKDRRQVDFLKIKNDLLEQHYEQLRQH
                     IQEVNTLRLEFVQEMENLQDLMHTDQTKAKNYVEKILEEAKNFEMLCSFCNHQVTNLI
                     LARYQKLAAKRNIQITFQADLPEELPINDDDLAQLLIHALEHSFRETHAIENPLYRKI
                     YLSIHEQEEHFVICCEHSAHYDTNLFSRGITEELDDQERFDLMMMKDVADRYTGTLTQ
                     EKDTFIDRITVQLSRNYPNPV"
BASE COUNT        14426 a         7832 c         9344 g        13279 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtag ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcgaaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga
    34561 tttttgtcac aacctcttta ttttttatat tttttaaaag tacgagaaat tataaagaaa
    34621 aaagcagtga tttgatgtgc tatttttata aaagctatgt gacaaaactg ttagtaaaaa
    34681 aacggtttct gtaagctaga cacatgtttc tttttgtcaa aattagttac actttgtgtg
    34741 aggttatatg aggagggaat ccaatgaaca aatggcgttc taatccaaaa ttgaattatt
    34801 ggggaaaatt catcattcga acaatttttt atagtgcagt actgctgttc ctgatttatc
    34861 tgtatcacta taaaaatatt caaggaggaa cttttatcta taacgaattt taggaggaag
    34921 agtatggaaa tcaaaacgat tattgaagca atcgatgatt ggggaataaa tgaacctgat
    34981 cgagttgctt atcaggcgga tgagacgcat acttttggtg aattgaaaca agcatcagac
    35041 gcacttgctt attatttaga aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc
    35101 aatttggagt ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg ccatgcctat
    35161 ttgccgattg aagagcatac acccaaggag cgtatcctat cgatctttcg ggtggctaaa
    35221 ccatctatgg tcatcagtat cggggactgg atagaagata ttccttcggt tcctgtcata
    35281 acaaaaaaag aatttcaaga aatcaagaag ataccagtag gattttatcc cagaaatagc
    35341 gtaaaaggta cagaaaattt ttatattatt tttacttctg gtactactgg agaaccaaaa
    35401 ggcgtacaaa tcagtcatga taatctagtc agctttgttc aatggacgat ggaagacttt
    35461 gggatcaagc ctggtatgca tttcttagcc caagcgccat tttcttttga tttatcggta
    35521 ttttctattt atcctgcatt agtttctggc ggaatgctga agccgttaaa taaagcagtt
    35581 gttcaagact ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt
    35641 tctactccat catttatgga tatttgcttg atggaaccta cattcaatgg agaaaatgtg
    35701 ccggaattgg acatgttttt attttgcgga gaagaattga cgaaaaaaac tgcagaaagt
    35761 ctacttgatc gattcccaaa tgcacggata tataatactt acggtccaac agaagcaact
    35821 gtagctattt caagtattca gattgaccag catgtactag atagttatga ccgactaccg
    35881 attggctacg taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa acctgtttca
    35941 aaaggagaaa cgggtgaaat cattattgca ggaccaagcg tatcaaaagg ttacctgaac
    36001 aatcccgaaa agacagctgc tgcgttcttt tgtcaaaatg acttagcaag ttaccataca
    36061 ggggatgcag gtagactaga tgaatatggg cttttatttt atgaaggacg tatggatcag
    36121 caggtcaaat tacatggata ccggattgaa ctcggggata tcgaacatta tctgctccaa
    36181 gacaaccgaa tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag
    36241 ctggttgctt ttgtcgtatt agaaaacaaa acgaaacagc cggattttca gttgactaaa
    36301 tctatcaaag aacaattact agaagttgta atggattata tgattcctca gaagttccat
    36361 tatgtcgatc tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa attaacagct
    36421 gaggtgaatc ctgaatgatg ttacctcata tgatccctta tgcagagccg ttttattttt
    36481 ttcttttagc cattgcgctt gtaccgatcg ttctatcttt attgatatgg gaaaaaagat
    36541 taccagttta tcaatcagca gtgacacttt tctttttatt tgtcagcttt ggaggtaatt
    36601 attggcaaca gggagcggcg ctgattgggt atgttttgtg gcagacgata cttgtatggg
    36661 gctattttgt ttatcggcaa aggaaaaatc agacaggatg gttttttgcc gccgttattt
    36721 tagcgataat tccactgttt ttaacgaaag tgactccttt ttttgaacat ggaaaagcat
    36781 cgttacttgg ttttttagga atctcttatt taacctttaa atctgtacaa atgatcatgg
    36841 aaataagaga tggcatgatc aaaacatata agccatttcg ttatatccag tttctgctgt
    36901 tctttccaac aatctcttct ggaccaatcg atcgctatag gagatttgaa aaagatcagc
    36961 tccatccgcc tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc caaaatattt
    37021 ttgtcggttt tttatataaa ttcattatcg gttattattt tggtcaagta ctgcttcctg
    37081 tagtgggacg cattgcctta cagcatggtg gtatttcatg ggcattagta ggttatatgt
    37141 acgtgtacag tatgtatttg ttttttgatt ttgctggcta tagcttattt gcagtcggta
    37201 caagctacat gatgggatat cagacaccaa tcaatttcaa taaacctttt ttatcatgga
    37261 atatcaaaga attctggaat cgttggcata tgacgctgtc cttttggttc cgtgattatg
    37321 tatatatgcg attgatgttc ttcatgatga agaaaaaatt ttttaaaagc aagatcgtaa
    37381 tgtcaaatat cggttatttt gctttgtttc ttctaatggg tatatggcat ggattgacgt
    37441 ggtactacat cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga
    37501 tccgatttaa gaagaagcat aaagagcagt tgccttctaa caaatttacg catggcttag
    37561 ccgtattttt gacatttcaa gcagtatgtt ttagcttcct gattttttca ggatttttag
    37621 ataaactttt ttttagctaa cgaatagtga catattaatt tatataacaa aggagaaaag
    37681 gaaaatggaa gaacaaattt tatcaatctt agaagaaata acaggaacag atgaagtaag
    37741 aaaaaatcgt gatattgatc tatttgatga agggttgctt gattctttag catctgttca
    37801 attattagtc gagctagacg gagagctgga tatccaagtc cctgtatctg aattcgagcg
    37861 agaggattgg tgcacaccga ataaaatcat tcaacaagca actgcattga agggttgagt
    37921 atgaaaaaga aactttttgc tattttcggc ccggttgttt tagctgttgg cttactgttt
    37981 gtgtttttta cctcctccta tcaagtagat atctctaatc cagaaacgat tagacgtgcc
    38041 tcttcttcca tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta tgcattatct
    38101 gaaaaacaat atattccttt ttttggctca agtgaattaa gcagaatcag tccatttcat
    38161 ccgtctgttc tggcagaaaa ataccagcga aactatcgtc catttttgct gggagcaccc
    38221 gggacacaat cgttaagcca atatatgatg atgcgttctg caggagatgc tatgaaaaac
    38281 aagaaagtcg tctttattat ttctcctcag tggttcgtta aaaatggtgt aaaaactgat
    38341 tactttaata cgtattattc tgaacttcaa acatacgact ggttgttttc aatgaagaaa
    38401 gtaacgcctg ctgatcgcta tttagctaga agattattaa ctttctcaaa agtaaaagag
    38461 aatgatacgt tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa
    38521 tctttgaatc agctgcgcag ccaatggaac atgctgaaga gagaggatga agtattcagc
    38581 aatattgggt tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa
    38641 caataccaag aaacagaatt atccatttta gcaaatcaaa ttggagaacg agaaacgacg
    38701 aataatccat tcgggttgaa aaacgatttt tatacgcatc gtatccgagc ccacgagcca
    38761 gagctcaaac agtcacaaaa aaattgggat tatcgttttt cgccagaatt ttctgatttt
    38821 cagctggtct tggatcaatt agcaaaaaac cataacgaag tattgttcat catcccaccg
    38881 gttaacgaga aatggagcga ttataccgga ctatctcaag aaatgttaca aggatttgcc
    38941 aaaaagatca aatttcaatt aaatagccaa ggattcaatc gaatagctga ttttgtcaat
    39001 caagcgggta ccaactattt tatggaagac acgatccatc taggctggaa aggctggttg
    39061 gctgcagatc aacagatcag accgttttta gaagaaaatc atattactgc tagtaagtat
    39121 catcttgacg atgctttttt tagcaaatct tggcaacatc aaataccaga taaactacaa
    39181 ttaaaataaa gaaaacaggc gagtgttgct cgcttgtttt ctttattttt gaatattctg
    39241 aataaaagat aaaaatacca agtttgcctg aacaaaaatc ataagcaatg gtataatcac
    39301 aatatgaata tagaaatggg ggaaaacatt tggatacaaa agaagaacag ctacttattg
    39361 atttaacttc tgcaaaagga gtacctggaa atgaagaaga ggtaagagaa gtattcagag
    39421 aatatgccaa accattcgct gatgatattt tttatgacgg tttaggcagt gtgattgcca
    39481 aacatggtgc tggcggaggc cccaaggtct ttatttctgg acatatggac gaagttggtt
    39541 ttatggtaac aaaaataacc gaaaaaggat tcttggaatt ccaaactctt ggaggttggt
    39601 gggggcaagt catgcttgct cagcaagttg aaatcaaaac acgtgaaggg aaaatcgtcc
    39661 acggtgtgat tggttccaaa ccaccacatg ttttaacacc tcaagtaaga aataaacctt
    39721 atgaaataaa ggatatgttc attgatattg gcgcatcaag ccaagaagaa gccaaagagt
    39781 ggggcatacg tcctggagat atggtcactc catatattga atacaaacga atgaatggca
    39841 gtaaatattt actggcaaaa gcatgggata atcgtatcgg gacagctgtt tctctgcgag
    39901 tattagagaa tctatctaaa gaagcacacc caaatgtttt attcgcagga agcgatgtgc
    39961 aagaagaagt aggcttgcga ggtgctcgaa caagtacaca ccttgtaaat cccgatattg
    40021 cttttgcttt agatactggt acagcaggag acactccagg aatgacacca aaagaagcag
    40081 attcgatttt aggaaaaggc ccacagattt tgatttttga tgcatctatg atcccgcata
    40141 aaaaattatt gaattttgtt attgatgtag cagaggaaat ggatattcca ttccaatata
    40201 cagtgatttc tggcggagga actgatgcag gacaaatgca tttgacaaga gatggtgttc
    40261 cgtctgtagc cattaccgtt cctgttcgtt atctgcattc ccatacatca gtgattcatg
    40321 aagatgatta tttgaataca gtgaaactag tcacagaatt agtgaaacgg cttgatagtg
    40381 aaacagttga aaaaattcgg agttatgaat aatgaataat agaataccta tttctgaata
    40441 tcggaaaaaa gcacgagttt ctttggaaaa tcaatgggga atcaatactt ggcttgtttt
    40501 cttatctata atatttacga gcgtcatcca gaactttttt gacggtttca gtccttttcc
    40561 ggaagaaagc atgcagcagc acttattgag ttttctagtc gataatttac ttttattcgc
    40621 attcaactat gcattgtttt acattgcgct agtagttgta cggggtggca gaccaaaaag
    40681 taacctttta ttttcagttt tccaaagaaa gtattttggt tcgatacttg gcatcaattt
    40741 gatcaattca gtcatcaact ggctactcaa cagtttaatc tttctgccca tgtttttaat
    40801 cagcggagtg agtacttata tgcagctgct tttcagttca aatgcggtac ctacgggtgt
    40861 catgccagaa gattttcttg atatcagctt tgttttatcg atgataggga tgatttttgt
    40921 ttcagcactc atcatgagta ttgttggcgg tttattccaa tttgctgcat ggacaaagtt
    40981 cgactatcct gatttgtcgg ttattcaatg tttgaaatat ggctggtttt tattgaaaga
    41041 tagaattggt acgtatattt tgttgcagct gtcttttatc ggctggtatt tgctaggagc
    41101 aatcgctttg ttcatcggtc ttttgtgggt cattgtttat gtgaatgtgt cagttgcaga
    41161 attttatgaa caagcacgga ttgaaaaagg aggtccagac gcctatttta cttagcatgt
    41221 aagcagttta ttcatcaaaa aaataacttt tgtggtagga taaatctttg agggggaatg
    41281 tacgatgaaa ttaactgttt taggatgctt aggagcgtat ccttataaaa atcaagggac
    41341 aacaggttat ttgcttcaat ctgacgggtt caatttgttg atcgatgcag gtagtgctac
    41401 gctgatcaaa ttacaagaac accttgatcc acttgatcta gatgctgtga tccttagcca
    41461 ttatcatcat gatcatattg ctgaccttgg tgtattacag tattactggc aacttcatcc
    41521 taagagaaat ccggagacat tgctttcaat ttatggacac acaaaagatt ccattcactt
    41581 tgaagaattg acgttggaaa atgtctcaaa aggacatcct tattttgaag ctgaagaatt
    41641 aaaaattggt ccttttctga ttacttttat ggaaacaatc catccagtag tatgttacgc
    41701 catgcgtatc gtagaagaaa caacggggaa agtattcgta tttacaggtg attcaggtta
    41761 tttggaaagt ttcgctgatt ttgcgaaaga tgctgatttg tttctagcag atacctatct
    41821 ttttgaagga aatgaacatc atcatgccca tttcacttca aaagaagctg gagaacttgc
    41881 gaaatcagct aacgtaaaga aacttgtact tacacaccta cctcagtttg gtgatttaga
    41941 acaattgaaa aatgaagcgc aaaaggcagc aggcaaaggg attgatatag aacttgctgc
    42001 agttgacaaa gtgtttaaca tttaggagga agaacatgat ttttgtacca aatgaaaacc
    42061 acgacccaag aatcaattta gcaattgaac aatatttgct gcaagaaatg cctttagatg
    42121 aacctatttt gctcttttat atcaatgaac cttcaatcat catcggcaga aaccaaaata
    42181 cgcttgaaga aatcaatcga gattatgtgg aagaaaatgg cattcatgtt gtccgtcgct
    42241 taagtggagg cggagctgtc taccatgatt ttggaaacct gaactttagt tttatcatgc
    42301 ctgatgatgg ggattcattc cgtgactttg cgaaagtaac acagccaatc atccaagcac
    42361 ttcatgaatt gggtgttgct ggggcggaat tgaaaggccg aaatgatcta gtcattgatg
    42421 gcatgaaatt ttctggcaac gcgatgtatg ctaccaacgg tcggatgttt gctcatggaa
    42481 caattatgtt cgactctgat atcaatgaag tagtcaatgc attaaaagta aaaaaagaca
    42541 aaatcgaatc aaaaggaatc aaatcgatcc gttctcgtgt aacgaatatc aaaccatttc
    42601 ttccagaaga aaagcaaaaa atgacaacag aagaatttcg tcaagaaatc ttgttgaaaa
    42661 ttttcggcgt agagtcagta gaagaagtaa aaacgtacga attgactgat gaagattgga
    42721 aaaaaatcaa tcgaatctct gaggaatatt atcgaaattg ggattggaat tacgggaagt
    42781 ctccagattt caatttctct cgccaaaaac gtttttctat cggttcgatt gaagtccatt
    42841 tgaatgtctc agaaggaatg atcaaagaag caaaaatctt tggcgatttc ttcggactag
    42901 gagatatctc tgacgtggaa aaaaaattgg ttggacagaa atatgataaa gcatctctat
    42961 caaaaatagt cagccaaatt gatgtgaaga aatattttgg tgcgatagaa ccagaagaat
    43021 tgcttacctt actttattga aaataaaaaa tagcggaatc cacatatatg gattccgcta
    43081 ttttttatac aggattcggg taatttcgag agagttgaac agtgatccga tcaatgaaag
    43141 tatctttttc ctgcgttagt gttcctgtgt aacgatccgc tacgtctttc atcatcatta
    43201 agtcaaaacg ttcctgatca tctaattctt ctgtgatgcc tcgactaaat aggtttgtat
    43261 cgtaatgtgc actatgttcg caacaaatga cgaaatgttc ctcttgttcg tgtatcgaca
    43321 aataaatttt tcgatacagt ggattttcga tggcatgagt ttctctaaag gaatgctcta
    43381 aagcgtggat caaaagttga gccagatcgt catcgttgat aggaagttct tcgggaagat
    43441 ctgcttggaa ggttatctga atattccgtt tggcagctaa cttctggtaa cgcgctaaga
    43501 taagatttgt cacctggtgg ttgcaaaaag aacacagcat ttcgaaattt tttgcttctt
    43561 ctaatatctt ttccacatag tttttagctt ttgtttggtc cgtatgcatt aaatcttgca
    43621 gattctccat ctcttggaca aattccaggc gaagtgtatt tacttcttgg atatgctgtc
    43681 gaagctgctc ataatgttgc tccaacaaat catttttgat ttttaagaaa tctacttgtc
    43741 tccgatcttt gtcggtattt aagatgtgat cgattagatt gtagctgata ataacgatta
    43801 gaatgataat atataaaatc gtagaccaat tgatcgttgt ttgatagata cctaatgccg
    43861 tttggatgta aatcaagcaa tggataatgg ctaccaagac gatccaaggt gtacaagcta
    43921 cataaaaacg gttattctta tatgcttcgc caatgcatgc aagtgaagtg actaaagtgc
    43981 ttataacact agcaatatta gcaatcggca ttaattcagg aagttctgca ggagtaaaag
    44041 ttgcataaag cagaacgccg ataaaaatca aaagttggaa cgtacaaaaa attccgtacc
    44101 attttttata gtaaaacatt cggctccaat agtagcagat gatgaaagct gacgttaaga
    44161 taataaataa atgagataaa aaagaatgaa cgaatggttc aaaaagaata ccacttaaaa
    44221 tatcttctga tacagcttca aatcctaatg ccaaagcaaa gcaacttaag agaataagtg
    44281 agtattcaag acgtttttgt ttatacatca agtagatcgt atagaaaaag gtccctatag
    44341 cgataaaaac agcgattatc atcgtcaata cttgcggcac tgattgtgaa taaataaaac
    44401 taatcaatgg tccagttgtt cctagataaa ctttcggtgg cagtccagca tagttctgat
    44461 aaggagatga gactgtaagg gtcaattttt ttccgatata atttgctggt aaatctatca
    44521 cagccaatga gagtccggga ttgctttctt cctgataatc tttccgttgg tataaaatct
    44581 tttcgcctag atatacagta atccattgat ggtttccttt gattagtaaa tttgcttcgt
    44641 ccaacggttt ttcaagtgtc gtttccataa tgaatgtttc gtctttatcc acggtaggaa
    44701 tcgtacgagt gtacttgctg tcaaacttaa aatcaggatc atcttttgta tagaaaaccc
    44761 acgaatcttt tatttctttc atttgattgc tgtccgcagg agaaaaaata aaataaaaga
    44821 aataagcaat tcctgttaaa aataacaatg ataatataat gattatgctc cactttatac
    44881 g
//
LOCUS       DADLIO010000016        41565 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.016, whole genome shotgun sequence.
ACCESSION   DADLIO010000016 DADLIO010000000
VERSION     DADLIO010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41565
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.016"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(65..595)
                     /locus_tag="JOX41_001009"
     CDS             complement(65..595)
                     /locus_tag="JOX41_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448770.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(694..1044)
                     /locus_tag="JOX41_001010"
     CDS             complement(694..1044)
                     /locus_tag="JOX41_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HAY6448771.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(1201..2730)
                     /gene="ahpF"
                     /locus_tag="JOX41_001011"
     CDS             complement(1201..2730)
                     /gene="ahpF"
                     /locus_tag="JOX41_001011"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HAY6448772.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     RTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(2740..3303)
                     /gene="ahpC"
                     /locus_tag="JOX41_001012"
     CDS             complement(2740..3303)
                     /gene="ahpC"
                     /locus_tag="JOX41_001012"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003756453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HAY6448773.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(3447..4109)
                     /locus_tag="JOX41_001013"
     CDS             complement(3447..4109)
                     /locus_tag="JOX41_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAY6448774.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            4293..5939
                     /locus_tag="JOX41_001014"
     CDS             4293..5939
                     /locus_tag="JOX41_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HAY6448775.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            5930..7012
                     /gene="uxuA"
                     /locus_tag="JOX41_001015"
     CDS             5930..7012
                     /gene="uxuA"
                     /locus_tag="JOX41_001015"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAY6448776.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(7120..8673)
                     /locus_tag="JOX41_001016"
                     /pseudo
     CDS             complement(7120..8673)
                     /locus_tag="JOX41_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
     gene            8821..9962
                     /locus_tag="JOX41_001017"
                     /pseudo
     CDS             8821..9962
                     /locus_tag="JOX41_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(10088..11167)
                     /locus_tag="JOX41_001018"
     CDS             complement(10088..11167)
                     /locus_tag="JOX41_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAY6448777.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVIDFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(11276..11716)
                     /locus_tag="JOX41_001019"
     CDS             complement(11276..11716)
                     /locus_tag="JOX41_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAY6448778.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTSLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTPQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(11773..12183)
                     /locus_tag="JOX41_001020"
     CDS             complement(11773..12183)
                     /locus_tag="JOX41_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAY6448779.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(12364..12798)
                     /locus_tag="JOX41_001021"
     CDS             complement(12364..12798)
                     /locus_tag="JOX41_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAY6448780.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVSFEERKQLFEKYM"
     gene            complement(12898..13746)
                     /locus_tag="JOX41_001022"
     CDS             complement(12898..13746)
                     /locus_tag="JOX41_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAY6448781.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAVLGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLFFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFVFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            14135..15901
                     /locus_tag="JOX41_001023"
     CDS             14135..15901
                     /locus_tag="JOX41_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HAY6448782.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETRRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVRDHLDYLTDLGVNGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVYDREDKLYFTRELEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            16003..17262
                     /locus_tag="JOX41_001024"
     CDS             16003..17262
                     /locus_tag="JOX41_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAY6448783.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            17409..18710
                     /locus_tag="JOX41_001025"
     CDS             17409..18710
                     /locus_tag="JOX41_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAY6448784.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            18713..19564
                     /locus_tag="JOX41_001026"
     CDS             18713..19564
                     /locus_tag="JOX41_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAY6448785.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            19577..20392
                     /locus_tag="JOX41_001027"
     CDS             19577..20392
                     /locus_tag="JOX41_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HAY6448786.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            20543..21709
                     /locus_tag="JOX41_001028"
     CDS             20543..21709
                     /locus_tag="JOX41_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAY6448787.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            21939..22586
                     /locus_tag="JOX41_001029"
     CDS             21939..22586
                     /locus_tag="JOX41_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis protein"
                     /protein_id="HAY6448788.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            22670..23614
                     /locus_tag="JOX41_001030"
     CDS             22670..23614
                     /locus_tag="JOX41_001030"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HAY6448789.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            23749..25200
                     /locus_tag="JOX41_001031"
     CDS             23749..25200
                     /locus_tag="JOX41_001031"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HAY6448790.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            25221..26057
                     /locus_tag="JOX41_001032"
     CDS             25221..26057
                     /locus_tag="JOX41_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAY6448791.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            26057..26716
                     /locus_tag="JOX41_001033"
     CDS             26057..26716
                     /locus_tag="JOX41_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAY6448792.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSIHQS
                     I"
     gene            26842..27531
                     /locus_tag="JOX41_001034"
     CDS             26842..27531
                     /locus_tag="JOX41_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448793.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PKDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            27537..28493
                     /locus_tag="JOX41_001035"
     CDS             27537..28493
                     /locus_tag="JOX41_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HAY6448794.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            28537..29049
                     /locus_tag="JOX41_001036"
     CDS             28537..29049
                     /locus_tag="JOX41_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAY6448795.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSGVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(29305..29853)
                     /locus_tag="JOX41_001037"
     CDS             complement(29305..29853)
                     /locus_tag="JOX41_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAY6448796.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(29942..31123)
                     /locus_tag="JOX41_001038"
     CDS             complement(29942..31123)
                     /locus_tag="JOX41_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HAY6448797.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(31359..32867)
                     /locus_tag="JOX41_001039"
     CDS             complement(31359..32867)
                     /locus_tag="JOX41_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HAY6448798.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATCLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            33026..33217
                     /locus_tag="JOX41_001040"
     CDS             33026..33217
                     /locus_tag="JOX41_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448799.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            33420..34337
                     /locus_tag="JOX41_001041"
     CDS             33420..34337
                     /locus_tag="JOX41_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HAY6448800.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            34330..35403
                     /locus_tag="JOX41_001042"
     CDS             34330..35403
                     /locus_tag="JOX41_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448801.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            35551..36069
                     /locus_tag="JOX41_001043"
     CDS             35551..36069
                     /locus_tag="JOX41_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448802.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            36050..36442
                     /locus_tag="JOX41_001044"
     CDS             36050..36442
                     /locus_tag="JOX41_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HAY6448803.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVVFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            36518..37453
                     /locus_tag="JOX41_001045"
     CDS             36518..37453
                     /locus_tag="JOX41_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HAY6448804.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            37586..38365
                     /locus_tag="JOX41_001046"
     CDS             37586..38365
                     /locus_tag="JOX41_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HAY6448805.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            38358..38675
                     /locus_tag="JOX41_001047"
     CDS             38358..38675
                     /locus_tag="JOX41_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HAY6448806.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            38919..40529
                     /locus_tag="JOX41_001048"
     CDS             38919..40529
                     /locus_tag="JOX41_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAY6448807.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            40686..41534
                     /locus_tag="JOX41_001049"
     CDS             40686..41534
                     /locus_tag="JOX41_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAY6448808.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
BASE COUNT        13647 a         7466 c         7984 g        12468 t
ORIGIN      
        1 acaatccaaa agattttttt ggattgttgg tttttatacg gtctatttta ataactaaaa
       61 atgattaacg tatagtcatt tttcttattc tgatgaaatt gataatctcc tggatgccca
      121 tgaaaatcaa aataaagccg aatatttgga atagaagcat caaacttttg aatggattga
      181 acaataagac gaatccgcca atcaacaaca gaatactact ataaacactc caacttttag
      241 cttttgtatt catgctgaag aacaactgga acaagctgtt gatgataaca gctaatccaa
      301 gaagaatcgg caggatagaa acgattgcag gtgcaaaagc atagacgatc agagctaaga
      361 tcaggaaaaa aagaccactg aacagaccga tactccaaga acctgttttc cttttaaaac
      421 ggtaagcctc aaaaagattc aacaacccaa gcaaaacaag ataggcggtg atcagataac
      481 cgataaaatg aaaaacagca gaagggttta gcacaatcgc aatcccagaa ataatataaa
      541 cagcagctct taataaggcg tatttttgaa tattttgttt aatcgtctca aacatataag
      601 aaaacctcct ttgacttatt ttaacgtgaa ctagtcattt taccaaatta aatgttacaa
      661 aatgagcgaa ggagaagaat atctctggaa aaatcaactt ctgaggatct tttccatttt
      721 tttgcctttt gctagctcat cgatcatttt atctaaataa cgaatttctt tcatcaagtt
      781 atcctcgatg tcttctactc gtacaccaca aacaacacct gtaatcaagg aacgtgaagg
      841 attggggaca ggggcttccg caaaaaattg ttcgaaagtc acttgttttt gtagttgata
      901 ttctagttct gtttgggaat aacccgtcag ccaacaaatg atttcatcta cttcctcttt
      961 tatacgatct tttctctccg cttttgctac atacatagga taaacgcttg caaaacttgt
     1021 cgtaaaaata cgattttgcg ccataatcag tcacctttct ttttttcaaa ttatttacta
     1081 cttatagtat ataagaaaaa gagaagaaaa agcgattatt caaaaaaaca aaaaggattg
     1141 tgacaaaatt cttgtcacca tccttttttc cgctctctga ctttttacaa tcttcatagc
     1201 tcaagtgcgc atcagataat cgaatgctcc taaagctgca gtagctcctg aacccattga
     1261 aacaatgatt tgtttgtatg gactatctgt acaatcacca gctgcgaaaa cgccggggat
     1321 attcgttgcg ccatttttct cggtcactat ttcatttctt ggattcattt cgatcgttct
     1381 atctagccaa tccgtattag ggagtaagcc gactagaatg aatactcctg aaacagctag
     1441 tgtatgcatc tccatcgtac ggcgatcgat ataggagaga gattctacct gattcgtacc
     1501 gctgatttct ttcgtcgctg catgtttgat aacagtgaca ttcgcaagag agactagttt
     1561 atcctgtaag atttgatctg cttttaattc tggtaagaat tctagaacat atacatgttt
     1621 tgctaaccca gccaaatcga ttgctgcttc aacaccagaa ttaccaccac cgataacagc
     1681 aatctctttt cctttaaata aagggccgtc acagtgtggg caataagcaa ttcctttatt
     1741 tttaaactct ttttcgcctg gtacattgat agaacgccag tgcgcacctg tcgcgatgat
     1801 ggcggttttt gctttaagtg atataccgtt agctaagcca atattaataa aatgttgctc
     1861 tttatttaag gaaacggcct gttgattcat cataatgtcg atagggtaac tacgcacatg
     1921 actttctact tgctgcatca attttggacc ttctgtgtaa gaggtaccaa tcatattttc
     1981 aatccctagt gtttcaacga cttgtccgcc gaaagaatca gcgacaagtc ctgtacggat
     2041 tcctttacgt gctgcataga tagctgcact actagctgct ggtccaccgc caatcactaa
     2101 tacatcataa ggttcttttt caaacaactc ttcttcaatc aaagggccag tgattttttc
     2161 aacaatttgt tcgatcgtca tgcgtccgct actaaattct tctccattta aaaacacagt
     2221 tggcactgcc atgatttttt tatcatcgat ttctttttgg aacatcccac cttcaatcat
     2281 cgtatgagta atatttggat ttaatacagc taatatattc aatgcctgta caacgtcggg
     2341 gcaattatga caagtcaagc taacataact gtcaaaatgc aatgtttgtg ttattttttt
     2401 gattttaaga ctcaaagatt cactgatttt cggtgcccgt ccactaattt gtaacatagc
     2461 cagtaaaaaa gaggaaaatt catgaccgag ggggatacca gcaaaaacga ttccactttc
     2521 tttgccaact ggattgatag aaaaactagg tgtgcgcatc gaatctcttt tttcccaaga
     2581 gattttagga gacatttctg ctatttcctt cgtaaattca gctagttttt gactattttc
     2641 actattatcc aaactaacag aaaaaacaat aggagattca atcagtgcta aatattgttc
     2701 gagattttgt ttagtttctt tgtctaacat atccaccacc taaatctttc caacaagatc
     2761 aaaacttggt ttcaatgttt cgccactttc tttccatttt gccggacaaa cttcacctgg
     2821 gtgggtacgt acatattgag cagcgcgaat cttatcaatc agtgcactag cgtcacgacc
     2881 gattccatct gcattgattt ccatagcttg aacgattccg tctggatcaa taataaatgt
     2941 tcctcgctga gctaatcctt gctcttcatc caaaacatca aaaatacgag aaatctgatg
     3001 agacggatca ccgatcatca cgtattcgat tttaccgata gcatctgatg tatcatgcca
     3061 tgctttgtga gtaaagtggg tatcggtaga gcaagaaaag acttcaacac ctaaagattt
     3121 caatgtactg tattgttctt gtaagtcttc taattcagta ggacaaacaa aagtaaaatc
     3181 agctggatag aagcaaagaa tactccagtt ccccataaga tctttttcac tgacttctaa
     3241 aaattctcct tgatgataag catgtgcatt aaattcttcg atttttttcc caatcaatga
     3301 catagtaaaa cctccaataa taattattta tttataatta ttgtaattta gttggagttg
     3361 caaagtcaat ggatattttg ttatttaata aagattactc aaaaacgaag gttaattata
     3421 aaaatagaag aggtcgcaag aaaatgctac tgctggaaat actcgggata acgttgagta
     3481 acagtttcct gttctttcag catcatgtgt aagtgcaatc ccgtttgaaa tcgagcttct
     3541 tctggttttt tatcaactaa agccttgagt aaatcataat gttgttccat gatcgtttcc
     3601 catggaagcc cctgaatggt cactcgtaac cagcggaaac gttctaaatg ggtattatgg
     3661 tcatctaacc agttccaaac ttcttttctt cctgcaattt cgaaacaagc ttcatgaaat
     3721 aaattatctg cacggaaaaa agcgcgttcg tcatttattt tgactgcttt ttcttgttct
     3781 tctaaaatcg tttctagcac tattcgtgtt tgtgtgtcca atttggaaca acattcaatc
     3841 atgatttgct cttccaactg ttctcggaca aagcgagcat tttctgcaga aacaagatta
     3901 attttggaaa catacgtacc actttgaggt atcgtataca cgagttcttg ctgacgtagt
     3961 tgaatcaatg cttcgcgaat gggagtccgg ccgatagcaa gatgttcctc cagtgccttt
     4021 tcagatattt tccttccagg ttctaagtca gcatagataa tttgtttacg aatcgcttga
     4081 taagcttgtg attgcaagct gcttttcatc tttattcctc caaaatcatt tctatgaacg
     4141 tagtataaca gaagaggtct gaaaaacaat ctggtatgtc acattaacta gtaaatttgt
     4201 ataaatagta aaattttggt tgacatagcg atttttattg cataaaattc acttgaatac
     4261 aaaaactaat atgttagttt aggaggggaa aaatgattga tttaaacaac tggaggaact
     4321 ttatccctga attatctcaa aaagaagtag aaatacctca ttttgaccgt gcatcattaa
     4381 gagaaaatgg acaaaaaaat cctgtctgga tccatttcgg tggcggaaat ctttatcgag
     4441 gatttcatgc agaaatcgct caacgtttag cggatctagg cgaattgtcc actggtgtca
     4501 ttgtttgtga aacattcgat gaagaaataa ttgaaagggc ttaccaagat tttgatgatt
     4561 tgattcttga agtggtcatg ccaagcagtg gagagttcgt caaacgtata ttagctgcga
     4621 cagctgacag tctgtattgt catccagatt gttctgaaca ctttgataag atgattcgac
     4681 actttgaaaa tcctagttta caattagtta cttttgctat tactgaaaaa ggttatcgat
     4741 tgaaagatac aaataataaa tatataggac cgattgcagt cgatataaaa aatggtccaa
     4801 agaagccatc acatacaatg agtattcttg ctgtgctact ttataaacgt tttttatctg
     4861 gagcttggcc gattgcactt gtctctacag ataatttttc acaaaacggt agtcaattac
     4921 gtacttcttt gctaacgatc gcaaaagaat ggcaaaagga aggttatgta caaaatacat
     4981 ttatccaata cttatcgaat gaagaaattg ttgcgtttcc atggacgatg attgatcgta
     5041 tcaccccgaa tccttccttg tcagttagca aaatgttggc aaaagagggc ttttcaaata
     5101 tgtcgatttt ccaaaccgca aaaggaaata atattgctcc atttgtcaat acagaggaca
     5161 tccattattt aatcatggaa gatcattttc ccaatggacg tccgaaattc gaaaaagctg
     5221 gggtattctt gactgatcgt gcaacggtag ataaagcaga tacgatgaag gtgacgactt
     5281 gccttaatcc tttgcatacg tctttagcta ttatgggttg tttactgggg tataggagca
     5341 tagctgagga gatgaaagat ccagatttat cgctgctagt ttctgaaatc gggtacaatg
     5401 aaggcctccc agttgtggag tctccaggta tcattgatcc aaagatcttt ctggaagaag
     5461 taattactgt gcgcttttct aatccaaata ttcctaatat gcctcagcga atcgccacgg
     5521 atacctctca aaaggtggcg attcgttatg gtgagacgat taaaaaatat atggaaatag
     5581 aagttaaaga cccgcagaca cttgtattca taccattgac tctcgctgct tggcttcgat
     5641 accttattgg cattgatgat caaggaaaac cattcatccc gagtccagac ccactattga
     5701 cagaccttca gcataagctt tccgatattc aactgggtac gcaagataca tcacatattc
     5761 atgagaaaat ggctcctatt ttgtcaaata aagaaatttt tggtgtagat ctttaccaag
     5821 cagagcttgg cagaaaaata gaagaaatgt tcatcaagat ggtagcagga ccaaatgccg
     5881 tacgaaaaac attacaggat tacttacaag aacatggagg aaatttatca tggaaatgac
     5941 ttttagatgg tacggatcac aggaagaaaa gattacctta gatgaaatca gacagattcc
     6001 tgcggtcaaa gggattgtag gcacattgat ggatatacca gtaggagagg tatggcctag
     6061 ggagaggatc aaagaactaa aagaagaaat tgagtctcgt gggttaacac taaaagtaat
     6121 tgaaagcgtc aatgtgcatg atgccattaa aattggatta ccttcccgtg agcagtatat
     6181 cgaaaactat aagcagacaa tccgaaactt ggcagaatat ggaatagaag tcatctgcta
     6241 taattttatg cctgtatttg actgggtgaa atctgacctt gactaccgct tagaagacgg
     6301 ctcatccacg ttagctttta tatctgatga tattccagat gatccaagag aaatcgtcgc
     6361 gcgcatcgaa cattccagca atgaatttgg attgccggga tgggaacctg agcgcttagc
     6421 tcctatcaaa tccttgcttg aagcctatgc atcagtagac gaagaaaaac ttcgagaaaa
     6481 ttttgcctat tttctccaat caatcatccc aacatgtgaa gaggtagggg tcaaaatggc
     6541 tgtacatcca gatgatccgc catactcgat ttttggatta gctcgaatcg taaagaatcg
     6601 agaagattta gattggttgt gtcgcatagt agacagccct tataacggaa tcactctttg
     6661 tacagggagt attgcagaag atccagaaaa tgatgtatat gggattttag cagaattttg
     6721 ccaaagagat cgaatcccat ttgcacatgt tcgaaatatt aaatttttag ctaatcgaga
     6781 tttctatgag gcaccacata aatccgaata cggttcatta gacatgtacc gcatactaaa
     6841 aacaatgtat gacaacggat ttaacggata catccgtcct gatcatggaa gaatgatctg
     6901 gaatgagaca ggaagaccag gatacggctt atatgatcga gcattaggtg ctgtttatct
     6961 aaatggatta tgggaagcaa tcgaaaaagg aaacaaaagt aaagataatt agtgaaaaaa
     7021 actgtaattt tattatgtaa ataagaagga tgttcaaatt cttgatacat aaatccggag
     7081 gttgttaata agcattcgga tttatgtatc ttatttggtc taggaagtaa cttgattttc
     7141 ttttttcgat tgatccatga gtgcttcttc ttttaattca aagatatatt ctgagatcct
     7201 cataatcact tttttccagt cttctggtgt gatgattcct tttaaaatat agattttttt
     7261 gatatgagaa ggcaattgtt tcaaagggca gtcgctgata acgatgttgc agttctccat
     7321 aaaatcattt tgtattttga tcgattcatt tgaaaaaatt tgttctatct taacgatcag
     7381 atctttactg atataaaaat cacgcgtata gttcacacca atcacaattc gcggctgttt
     7441 tttgtagcga tcatacaaat gtactaggtc ttcaaccatc cattgcacat tttccttttc
     7501 taaaataact ggtaacaagt gttgattttg ttctctgaaa tccatataaa attgttcaat
     7561 ggcggtttgg acttctttca atacgctatg ttcttgataa agcatgaaag taggaagggg
     7621 cgtatttggt tgattgaagt taagaaatcc attataaagt ttatttcgtg cgaatgccaa
     7681 tgagtaaaga atcttttctt tttcaggtat aaacaaatca aatacagtac aaagggactc
     7741 caccatttct cttgaataaa gaacatgagg aacgtttgct ttttttaaaa gtttgtattg
     7801 ctccaagctt gtttcttccg attcgatttt cgtgatagaa agtcgagcta aaatattcac
     7861 taagatgcgt tgttcgcgac aaattggcag attaggtcgc aaaatatcta cagagagatc
     7921 aataaaaaag tcaatatatt catactctgt gaattctttt tgtacgtctt tcacagaagt
     7981 tgcaggaaaa ttctctttac atatttttaa tagaaaatat aatttatcta tcataccgct
     8041 atttagtcgg tcaagtactt cttttttaaa aaaagtattc atcataaaag ccactacttg
     8101 cggatcttca tcataaaatt ctgtagcagt acttgaaaag atgttccaat aaatatctaa
     8161 tgctgcatat tgaatttgta cctcttttcc agaaaaagac tttctgccat tattagaaaa
     8221 ggagatagac aaaccgtact atgctaaaaa tgcattaatc tttttcattt tcgtatacaa
     8281 ataagaggca ctatagtttg tttgctgact gaaactgata atcgaatttg tctgacagct
     8341 gaacaaagaa gtcaagatct gataactgac tgattcgttg cagtatcttc caaatagacg
     8401 ataatagcag taagccggat caattccttc aaaattcaac tttaaaaaag gtttttgctt
     8461 atcaatatgc agttctgtta gattgagacg ctcaaagtct tgttctaatt ctttgatgta
     8521 tagtaaaaaa tttgattcag acatatggaa atgatctgct aaatattgtg tagtaataaa
     8581 gaaacgatgt tcagatagga aaagaaaaat atctaatttt gtattgcttt ttttcttcaa
     8641 gataaacgtt ttaatcgctt cttgagtttg catgaaagag gctccttttt acttaaattg
     8701 ttaaaacttg aaaatattac tgtttttttc ataaatttag acaaaaaaac agtaaacata
     8761 taggtagaat ctctactatc ttatttcttg catacaaaaa aatcaaggag tgagagagtt
     8821 atgagatatt caaccatctt aatatcaaca tttgcagcct taagcttatc gcttactata
     8881 aatcagacag tccacacaga ggagacagaa acagccaaat ggacagaaac caagtgggcc
     8941 aacgtcaatc gaattacctt tcaggatgaa ttttcatcct tcaattcagg agtcgcaaaa
     9001 ttaagaaaag gacaaacagc gaccatcaaa gcaaaaattg actattcggg agacttagca
     9061 cctatactac aatcagctgt tacatttgag aatgttgatc ccactttgtc gattggctat
     9121 gacgagaaca ctttgactat ccaacacaag caagcgatat ttaccttcac cgttacatta
     9181 aatcaggact tgttaaaacc agcgcttttt actgtcaagg tatcagatgg actaccgaac
     9241 gatcatcatt taacgccgta tagtcagcgg cagacaattg agcaagattc agccatcgac
     9301 tcaggaggag atcttgttga agaaccaaca gataaaccag aaaatgaaaa taagccagaa
     9361 gtaccgccta cagaaaatcc agacggagaa cagaaaccgg aaatagaacc tggagaagaa
     9421 cccgatacag aaactcaacc agagccagac aataaatcaa aacctgaaat aacccctgga
     9481 gaaaaaccag atgtaactcc agaaccagat acggattctg gaaaccaaac agtaccggaa
     9541 acaaatccag acacagataa tgaaactgaa aatccagaaa aaccagaggt agatccagaa
     9601 gaaaaaccag atgtgactcc agaaccagat acggacgcaa gagaccaagg aataccagaa
     9661 aaaataaaca aaaaaacaat tcaagaggat ggaaaaaaag agagtaaaaa atcaaatcta
     9721 gcaattctaa aaataaatga agagcagctg aataaaaaat cacgaatatt tgatagcgcc
     9781 caatcagctg aaaccttaaa aagtagcaag gatacaacct ttgctgtcct gaaacgaaaa
     9841 ataaacagct accaaaatcc ggagagtcac aaaacaaagt tatactgtgg agcggaatca
     9901 ttctattaag tatagcaaca atgctttctg caaaaagatt taaacaaaac agatctctct
     9961 aacatttgaa taatgtctgt gaacgcattt ttcaaataaa aagaaatatc cagaaaatga
    10021 ccccaaaata ccagattgaa atctgatatt tggggtcgtt catactttat ctttcttcat
    10081 atttatttta agggatatct gtttcttttg gaagatggtt cgggatcttt ttcactttca
    10141 atacatctaa aaagaaggta aagatcggaa tgccgacaat caagccccaa acgccaaaga
    10201 accgttcgct aacaagtaag accacaaatg tataaaaaat cggcagttct gttttgctgg
    10261 acatcaactt cggattcagc acataagact caattagatg gacaatcaaa atcgtaatca
    10321 ggatataaac aacatctcgg atgcctcctt gggaataagc tatgaaagat agaggaatac
    10381 aagaaatgat aacacctgct actgggatca gacttaaaat gaaaatcatg atcgctaaac
    10441 tcagcagctg atgaaagcca aatacagcca aggcgattgt agtgagcaac gtatttaaaa
    10501 gagcgacaac aaattgagct tctaatacca aaccaaatgt attgacaaac ttatcggcaa
    10561 aatagtaaat atcttgaaag aaccaagaaa attcactttt taaaaacaat cttgagaata
    10621 caattgtttt tttcttttca atcataaaaa agaaacttaa gatgaatgac atagcaaacg
    10681 ccactgccat ttttcctata tcctgtaaat agccaagcgc aatcgaagcg ccattttgaa
    10741 gctgttcaaa aaaatcgttt cgctcaatat aagtatggat atattgtaaa acaggatctg
    10801 catcttttgg ctgatgctcg taaaaatcaa taacggactg gatcatatca aatgtttgat
    10861 gaataagcat cgggatatac tttgtgaatg ccagatagat aaggtaaacg atcagtgtat
    10921 aaatcatgat agctaaaaca cctgtaggga ttcggacaaa tcgctgaatg atttgaacaa
    10981 gatgaatcat caaataagta aagataaatg tgagcaaaat ggttgtaatc atacttctaa
    11041 ctaagaaaag aacaaaaacg acaaataata aaacagtgag acggcgtatt ttttcattcg
    11101 ccaaaaaacg ctgataaacg gtcaaatcga caacctccaa ataacaaaaa ataaacacgt
    11161 tattcattat atgatggaat atgaaaataa gaaagagaaa gagcaaaaag aaaaaccgct
    11221 aaatgacgtt atcttatgag ttggttttcc tcataaaatc gttcatctag cagtttcagc
    11281 cctttttctg gtcttgatga aaattatcta gcatttttcg ggtcagatgt tgcagtgtat
    11341 ccaattcttc ctgttcaagt ggaagataag acttgatctt ttgtggaata ccttctgctt
    11401 gtttttgcaa cgcagcacct tgaggagtca gcgtaacatt tacgattctt tcatcacccg
    11461 tttcacgctg acgattaata taattttttt ctgctaactt ttttagtaag ggagtcagcg
    11521 taccagaatc cagacacaaa tcatttccta gctctttcac tgaagtcttt ttcttttccc
    11581 ataaaactaa catcacaaga tactgggtat aggtaagatt cagcggcttg aggagggaag
    11641 tgtagtgtct aatgatttcc ttagaggcgg catataaagg aaaacatact tgattaacta
    11701 aatatagatc ttccattttt ccacctccgc tgttttacta tagtgtatca tagcggattt
    11761 acacaaaaaa gtctattcac taactgcttt cagagtaact tctatatttc cagctgtagc
    11821 ttttgaatac ggacacactt tatgcgctgc ctctaataat tcttgcgttt cttccagaga
    11881 aagaccttcg atagatcctt caatctctac acctaagaca aagctcgttt cactttctga
    11941 ataaagggaa acttgtgcac tgacagtaga agccccagag atattttttt gctgtttgat
    12001 caattctaat gcactgttaa aacatgcact gaaaccagct gcaaacaatt gttcagggtt
    12061 ggttgcattt tcgacgcgtt taccaggagc tgcaatattc aattcgaatg tacgatcggg
    12121 attatgaact tctccagagc gtccgcctgt gttgatcatt ttcgtagaat acattttttt
    12181 cataaaatta ccacctttaa ttatatttta tacaattgaa ttttacacaa tataattgtg
    12241 gaaagcaaag aaatggattg gcataagata aataagagaa agcacatgaa acagacgcgc
    12301 tttctcgaat agcaaacata tacaaaaaaa tatcagagac aaaaactaat ctcatcataa
    12361 acattacata tatttctcaa aaagttgttt tctttcttca aaacttactt cacgatggac
    12421 ctgatgaagc atccataaat aaccaaaagg atctctgaac attgagttag tcacaccaaa
    12481 gtccatcatt tctgtcattt cttgaatctc tacacagcca tttcgtaatg ctttattatg
    12541 tgtgtcctcg atatcagaga cgatgatatt gaaccagatc gtatttggat gttcagcagt
    12601 aggagcagtc aaaccaagag acgtgttttc atccagcata tggaatctcg tgccatacaa
    12661 ggtaaaaatg acttcattat tgcctctagg gtaatctgtt gcctcaatca gttgtatttc
    12721 atcaaagatt gtttgataca gttctagtgc tttcaaacta tcatttaata caaaatctat
    12781 ttccgttcct ttatgcataa agatctcctc tccttttcag tcgaacagtt actagattct
    12841 tttattatac cagttaaaga aaacgcattc aaaaaaatag cggatttact taccaactca
    12901 ttcgattgga tgataagtaa atccgcgtcc cattacttct gctacgctgc tgacaatgac
    12961 aaaggcactt ggatcgattt cttctatcaa tggtttcatt cgggaaaatt catgatcagt
    13021 cacaacgatc aataaaacct cttttgactt tcgattatac ccgccttttg cctctagcag
    13081 ggtaaggcca cgtccaatct cagcacttaa gcgaaggcgg atgtcttcca aataatgttc
    13141 actcatgacc ataacagatt tctttcgatt gatacctgtt tcgatataag tcatgacaat
    13201 tgaagtgatt gcaatagata aaatagcata aagaaactct tctattccaa aaacaaacag
    13261 attaagagaa acaacgaatg cgtctgtaaa aaataagcca atcgaagtat tcaagtggaa
    13321 atatttttta aaaatgaggg gagggatcgt cgtaccgccg ctagaagagt tgtttttata
    13381 taaaatcgca actcctaaag caaaaatcgc acttccaaaa atgacagaca acaaccgatc
    13441 tgaagtaatc attgtttctg gaactattgc aatgattaaa ggaaaaaaca agcttccgaa
    13501 aagtacttta aaaaagggtt ttttacctaa aaatagaaga gctagtacca acataacgat
    13561 attcaacact aaaataacta tagctcggtc aaatcctaaa acagcttcca gtaatattcc
    13621 tagaccgctg acacctccag cagcaatatg atgaggccct aaaaacatat tgatagcgac
    13681 tcctaatatg aagagggcaa aaataatctt aatgtatgtc catataaatt gtctcgtttc
    13741 tttcatttat ccacttcctt aattcattaa taatactctt atcttattat aacttacttt
    13801 tcaccttaag ttaactttaa ttaataaaaa aattaggcta gtctaaatta ttatgtttca
    13861 ttcttctaga atatacttct acgttaaaaa ctgttaaaaa acttttactt tagaaaattg
    13921 gagaaattga tcgcttaaga taaattcagg acactaaata gtacaggaag tagattaaaa
    13981 cttttaaaag ttttaagtct atctatttgg caagtttaaa aaataaaaat tcggtatcaa
    14041 aaaactgtta ccgataacat ttttgaaagc gttgtctttt gtttctctat cacttatagt
    14101 gatgacgtca tattaaaaca caaggaggaa atcaatggat acagctgcaa tttatcatcg
    14161 accggaaagt gaatatgcat ttctatatac gaatacaaga tttcgtattc ggcttcgtac
    14221 taggaaaaat gatatcaaaa aagtatatgt gctttgtgga gatccatata ccataacaac
    14281 tgaaaaatgg tatcaaaaac aacgaccaat gaaaaaatgt ctaagtacca atgttcatga
    14341 ttattgggaa attgaagtga cgagcgaaac aaggcgctta cagtatgcgt tccatgttgt
    14401 tggggaagat aacacggact gtttttacgg tgatcaagga atttttcctt atcgagaaaa
    14461 tgtgattact gaaccaaatt tttattttcg aataccttat tttcatcaaa tcgatcgatt
    14521 cactattcca gaatgggtaa aagaaacagt atggtatcaa atttttcccg aaagatttgc
    14581 aaacggggac aaagcaaatg accccgaaca cactttacct tggggaagta aagatccaga
    14641 ccgagaagac ttcttcgggg gagatttgca aggtgtgagg gatcatttgg attacttgac
    14701 ggaccttggc gtcaatggca tctatttttg tcccatattt aaagccacat ccaatcataa
    14761 atacgatacg attgattatt atgaggtgga tcccgctttt ggcgataaaa aacttttaaa
    14821 aaacttgatt gatgaagcac ataaaagagg gatacgtatc atgttcgatg ctgtattcaa
    14881 tcatatgggt gtccattcac cacagtggca agacgttctc aaaaacggag aaaaatcgat
    14941 ctataaagac tggttccaca tccgtttttt cccagtagat tcttatcaga tgactgactt
    15001 accagaaact gctgaaaata tcccatatga tacttttgct tttactccat tcatgccgaa
    15061 actaaataca gcaaatccag aagtgcaaaa atatttgctg gatatcgcaa cttattggat
    15121 aaaagaattc gatattgatg gatggcgtct tgatgttgct aatgaagtcg atcatcattt
    15181 ttggaaaaaa ttcagagaag cagttacaga aatcaaacca gacatctata tccttggaga
    15241 gatttggcat tcctctcaag cttggctgca aggggatgaa ttccatgcag tgatgaatta
    15301 tgcattcaca gattcgatta aagattattt tgcaaaaaag aaaatcacag cttcacaaat
    15361 ggtcagtgga atgaatcatc agcaaatgct ttacagagat caggtgaacg aaggaacatt
    15421 caacttatta gattctcatg atactgccag gatcttgacc ctttgccaag gtaacaaaga
    15481 attgatgaag tctgtgatgg cctttatgtt tcttcaaaaa gggtctcctt gtatctatta
    15541 cgggacagaa atagggatga ctggtgaaga tgacccggat tgccgcaaat gtatgatatg
    15601 ggagaaggag gaacaagatc tagagctatt cggttttata aaagaacttg tttctctaag
    15661 gaaacagttg tctaagatta tttctgaagg ttctactcag tggctaatag tatatgatcg
    15721 tgaagataag ctctatttca cacgggaact agagggacag atcatctatg tttactttaa
    15781 tcagtcaaaa gaaccttggg tagtagaaca ggaaaatgag gtgattctta gtcaaaattg
    15841 tcagttgtta gaagacggga aagcagagat acgacaatac ggatttttga tcatgtgttg
    15901 aaaactgtta ccggtaacaa caagaaagcg tttgcaaatg aagatttgtg cccattataa
    15961 taagggtgta acagcacgtt gaatacacag gaggaaatga agatgaaaaa aagaagtgtg
    16021 aaacagttgg gtttagggtt aatctcttta ggaatcttag gcggattagc ggcttgtggc
    16081 aatggtaact cttcagcaga aggggaagcc gatgaaggaa aaacgttaac agtttccgtt
    16141 gattctggat ataaagatta tataaacgaa ataaaaaaca ctttcgaaaa agaaaacgat
    16201 gtgaaaatca agctagtaga aaaggacatg ttcgatcagt tggaatcatt agcgttagat
    16261 gggcctgctg gaaagggacc tgacgttatg atggcagcat atgaccggat cggtgcgtta
    16321 ggacagcaag gacatctggc ggaagtaaaa ctgggaaatg aagcagctta cgatgaaaca
    16381 gacaaagccc aagtgactta tgatggaaaa atctacggag aacctgcagt aatcgagacc
    16441 cttgttttgt actataacaa agatttagtc gatacagcac catcaacgtt taaagatttg
    16501 gagaatctat ccaaagacag tcgttttgct tttgagtcag aagcaggaaa aaatacagga
    16561 tttttagcta aatggactga cttttattat tcctatggtt taattgcagg ttacggtggc
    16621 tatgtatttg gtgatgatgg cacaaatcct tcagatatcg gtttgaataa tgcaggtgct
    16681 gtagaaggaa tctcttatgc aacagattgg ttcaaaaatg tttggccaaa gggaatgcaa
    16741 gacataaaaa gtgcaggaga cttcgccagc cagcaattca tgtccaataa aactgcagca
    16801 atcattgacg gtccatggca agcgcaaaca tacaaagaaa acaatatcaa ttatggtgta
    16861 gccaaaattc ctactctaaa taatggacag ccttatcaac cgtttggcgg aggaaaagga
    16921 tgggtagtca gcaattatgc taaaaacaaa gacctctctc aaaaatggct tgattatgta
    16981 acgaatcagg aaaatcaaga aaaattcttt gaaatggtaa atgaaatccc tgcaaaccaa
    17041 caagctaggg aaacagcaaa ggctaaaaac gatgaattaa caacagctgt gattgaacaa
    17101 tatgaaacag ctcaagcgat gccaaacatc ccagaaatgg gcgaagtttg gacaggtgca
    17161 gaaaacttga tgttcgatgc agcatcaggt tcaaaaacac caaaagaatc cgcagatgaa
    17221 gcagtaaaaa caatcagtga agccatagaa caaaaatact gattaaaatg ataaccgtcc
    17281 atttttataa aaaatggaac aggtgcttca gataaaagtg gcaagagcga gatggaaaat
    17341 tatcttgctc ttgttgccat tatcttaaaa gcagtttgcg gtttagcaag tttagagggg
    17401 gcattcagat gcagcaagat aaaacaagca atatcaacga aaaaaaaatc acgctttgtt
    17461 cacttattcc agggatgggg cagtttgtaa atggccaagc ttttaaaggt atcgtttttt
    17521 tcgccatatt cgtcctattc attggtcaga tgcttctggg cggatttcat gcattggtag
    17581 gattggttac tttgggaagt ataccaatgg aagatcattc attatttatt ttgattgaag
    17641 gcactttgca attcatcatt acaatcattt tcttgatttt ttacggtttg aatcttttag
    17701 acgcttatcg agtagcgaag atgcgtcaag agggcaaaaa aatcaatcgg acgatgaagg
    17761 aagtcataca taatataggt gatgaaggtt ttccttatct attgacactt cccgcttatc
    17821 ttctcatgat ttttacgatc attttcccag tcctagttac attgttcact gcatttacta
    17881 attatgactt caatcatatt ccaccagcca gtttaattga ttgggtaggg gctaaaaact
    17941 tttttagtat cttcttttta agctcatatc gtaatacttt ttttgcagtc ttttcgtgga
    18001 ccgtgatttg gactttatgt gcaacaactt tgcaaatcac ccttggtatt ctcacagcgg
    18061 ttgttgctca ccagaaattt attaaattca aacgtatttt cggtatcatt ttcttattac
    18121 catgggcggt cccagctttt attactatca tgagtttttc gaatatattc aacgatagcg
    18181 taggtgccat caatactcaa gtgattcctt tcataaacca gcttcctttt gtagatatca
    18241 gtgcaatctc ttggaaaacg gacccgaact ggacgaaagt agcaattatc ttagtgcagg
    18301 gctggttagg atttccctat atctatgtga tggttacagg aatcttacaa tcgatttcag
    18361 aagacttata tgaagcagca aaaatcgacg gagcaaatgc atggcagcgc ttttcaaaca
    18421 tcacgcttcc tgctgtcttc ctagtggcag cgccaacatt tattacacag tatacgggga
    18481 atttcaataa tttctccatg atctatctgt ttaacaatgg tggtcccgga agcgtaggcg
    18541 gaggagctgg ttctactgat attcttattt cctggatcta taaacttacg actggaactt
    18601 ctccgcagta ttctatggct tcagcaatca cgttgattat ctccgtcatc gttatctgtg
    18661 tgtcattgct ggtatttaaa aagacaaatg cgttcaatat gggggattaa caatgaaaaa
    18721 atttcattcg agtgctcgat tccaaaaacg actttctcac ttttttactt acttttttct
    18781 tttaatactg tcagtcatta tcatctatcc gcttttgatc acagcaagta ctgccttcaa
    18841 gtcaggaaat attgcagctt ttagtttaga tctttcaagt gactggactt taggaaactt
    18901 tactcggcta ttcagtgaaa cactttacgg gacttggtat aaaaatacat tgatcatttc
    18961 tgtcctaaca atgatcgtac aagtgactgt agtaactttg gcgggctata cttatagtcg
    19021 ctatcgtttt atcggccgca aatcaagttt gatgttcttt ttagtgattc agatggtacc
    19081 gactatggca gcattgactg ccttttatgt catggctttc ttattagaag cgctcgataa
    19141 gtactggttc ttgacaatga tctatatagg cggtggaatt ccaatgaata cttggctgat
    19201 gaaaggatac tttgacactg taccaataga tttagatgaa tctgctaaac ttgatggggc
    19261 agggcatttc aggatttttt tccagattgt attaccgctt gtcaaaccga tgctcgccgt
    19321 tcaagcatta tgggctttta tgggaccttt tggggatttc atgttagcta agttcctgct
    19381 tcgaacacct gaaaatcaga ctgttgctgt cggcttacaa acatttattt ctgatgtgac
    19441 aaaccaaaga gtctctcttt ttgctgctgg ggcaattttg attgcactac cgatttgtct
    19501 attattcttc tttttacaaa agaactttgt taccggcctg acatctggcg gaacaaaagg
    19561 ataggagcag agtatcatgc aaacatttcc gttaaactat ttttccgcat tacgtacgcc
    19621 aactcaagtg tttgcgggac gcaaactatt atcatggcct aaatttttct tgatatttgt
    19681 atttttagtt tccttgatgg tcatgcctgt gactcttttt tatgccaatc agatccaagc
    19741 gattccatta gaacaatttc tatccgttca ttcgctgatc gatgaacaag gaacccaaaa
    19801 attttctgaa cttgaattat ctgaaactgg gttacaagca tcgcaacaaa cgatagctgt
    19861 gacccctgaa attttggtag gtgtgtcttt atctgagaaa caacaatccg atcatggaac
    19921 ttttattgat tttgagaagg aacaatgggt gatccaacaa aaggataaat ctggtatacg
    19981 ccgctatacg atgaattata gcccatcttt ccaaccagat tctgtacgta cgcccgaaga
    20041 tttccaacga tttttagaaa gagaatttta tgccagtaat cgtccaacaa tcattttatc
    20101 ttatagttta agtcttggtc ttgtcctatt tgtcatgacg agtctcattt tattcggggc
    20161 ttcctttttc ttgtggatga caagaaaaag ccaactttca tccattcata cattcaaaga
    20221 gagtgcaaat ttgatgctga atgttatggg aataggttcc atggcagcag cagttgtagg
    20281 gtttatccac tttgacttta tcttgatgct aagtgtccaa acaacgataa ctgtcttgct
    20341 gcttttatgg gtttttgtca aaacaagatt caaagataag cgtgtcgaat gacaagttta
    20401 agcgatttat gcgacaatga atgtgaaaaa aatgaaaaat aaagtagttt ttgaaaaatt
    20461 tctgaaaaaa ttaaacttct tagttgattc ttttcttttt tagtattaac gtaatagggt
    20521 agttttttta aggaggaaaa tcatgttaga gaaaacttta tacaatcaat tattttcacg
    20581 ttctttctcg ctccctgtcg aagtaaatta ttgggacggt acaacgaaac aatacggaga
    20641 tacggacact cctccccaaa tcaaaatcaa tatccatgaa gaaatcccaa tgaaagagat
    20701 tacaagtaac gcttctttgg cactaggaga agcctatatg gatcatcgaa tcgagatcga
    20761 gggaagtatc caagcattga tcaacgatgc ttatcagcaa gcaaacagct ttttacgagg
    20821 aaaagattat ctaaaatggc tgccaaagaa agaaaaacat acgaaacaaa aaaacaaaga
    20881 agatatccat gcgcattatg acttaggtaa cgacttttat aaactttggc tagatccaac
    20941 tttgacttat tcttgtgctt atttcaatac acctgaagat acgttggaac aagcacaaat
    21001 caataaagtc catcatatct tagacaaact ctttatcaaa gaaggcgaaa cgttgcttga
    21061 tatcggttgt ggctggggaa cattgatgtt cactgctacc aaagagtata atgtcaaggc
    21121 aactgggatc acactaagtg aagaacaata cgatttgatt accaaaagaa taaaagaaga
    21181 acatttagaa gataaatgcc gtgtattatt aatggattac cgcgaactaa aaggcgaaac
    21241 gtttgatcat atcacaagtg taggtatgtt cgaacatgta ggttctgaaa atcttgaagg
    21301 ttatttcaaa gtggtaaaag atttattgaa accaaaagga acagctttga tccatggaat
    21361 cagccgacaa caaggcggtg cgacaaatgc ttggatcaat aaatatattt tccctggcgg
    21421 ttatgtccct ggtgttactg aattagttga taatattaca aaaaacgatt tgcaactgat
    21481 tgatttggaa agcttacgtc gtgactacca attgacatta gaacattgga caaagaattt
    21541 tcatcaagtc caagatcaag tcacgaaaga aatgggtgat tccttctatc gaatgtggga
    21601 tctatattta caagcttgtg cagcttcatt tgaatcaagt aatatcgatg tgattcaata
    21661 tttgcttgtt caacctggaa acaatgacat cccaatgcat cgtgcataat tgaggcaaaa
    21721 gtactgttta aagactattt aaaaagaagc taagttttat gatgctccag aagtgaactt
    21781 ttttgtctaa cttctaggat tgtctctaaa gcttagtttc tttttcttta tattttcata
    21841 ataaaagttt ggttctttaa tttttaaaca tgacagaaaa ttttttcttc gttatacttg
    21901 taatagaata ctattttata acaaagggga tcgaatcaat gaaaaaaact gttatttata
    21961 ctagtttatt tgcagctttg tttttagctg cttgtcaatc aaataccaat caaggcacat
    22021 ctgggaatac gtcttccagt agcgaacagc gctcttcaca ggtatcggac tcctcaacaa
    22081 aagcaagcac atcttcgtct agccagacaa aaagttctag tgaagcaagt actcagtcag
    22141 atatcaaagt gtctgcagct cgtgcgatcg aattgttcca agataaatac ccagatactg
    22201 caattactag tttggaatta gatagtgatt ggggatctta cttctacaag atagaaggtg
    22261 tcgatgatca aaaagaatac gaagcaagaa ttgatgctca aaatgaaaaa atggagacag
    22321 agaatccaga aactctagat cgagatgaac aaaatggtca aaagaaaaaa gaagatggtc
    22381 tggatgttga taaattgatc acgattgagg aagcagcaaa aatcgccgtc gacaaagtag
    22441 gaagcggtac ggcaacagat tgggatttgg ataaagattt aggtactact tattgggaag
    22501 tcaaagtaaa agacggcaat caaagtacat cagtcaagat caatagccaa acaggcgaag
    22561 tactgtcaac tgaacaagat gattaagaat ttcttcggaa aacaagagtt gatttttctt
    22621 ttagtcatga tacactagac aaaataactt gtttgaagga gcgatttact tgagtttaga
    22681 aacgaccttt gccaatcata tctttgccaa tcctttgatg aatgcatctg gtgtccactg
    22741 catgactacc caggaattag atgaactggc tcattcagaa gcaggagcat ttatcactaa
    22801 gagctgtacg atcaatgaac gaaaaggaaa tcccgaacca cgctattttg atgttccttt
    22861 agggagtatc aattctatgg gacttccaaa cttaggtttt tcttattatc tagagtatgc
    22921 tcttgcgtat gaaaaagtgc aggaaaacca aaatcaaccg ttattttttt ccattgccgg
    22981 gatgagtgtc caggaaaact tggaaatgct tgagaaaata gaaaaaagtg ggtttaatgg
    23041 gatcactgaa ttaaatttat cttgtcccaa tgtgcctgga aaaccacaac tagcttacga
    23101 ttttgaggcc acttatgaaa cactgaaaga agtattcagc atcttttcta agccgctagg
    23161 aatcaaattg cctccttatt ttgattttgc tcattttgat cagatggctg atatcttgaa
    23221 tcagtttcca ttgacctatg tcaatgctat caacagtgtg ggcaatggtt tgtatatcga
    23281 tacagaacaa gaagcagtag tcatcaaacc aaaagaaggg ttcggcggca ttggcggaga
    23341 gtatatcaag ccgactgctt tggcgaatgt tcgcgctttt tatacacgtt tgaaaccaga
    23401 aatccaaatc attggtacag gtgggattcg gacaggacaa gatgcatttg aacatctgct
    23461 atgtggcgca agcatgttac agattggtac agagcttcat aaagaagggc cggaaatttt
    23521 ttctagaatc ataaaagaat taacgcagat tatgtcagaa aaaggatata cgtcaattga
    23581 cgaatttaaa ggcaaattac gcaccatttc atagcaaaga gacgaaggtc atgattgatc
    23641 ttcgtctttt tttataaaaa acactcgtct gttcattcct gtgcaagcgt actcattgta
    23701 tgttagacga acttgtggga aaataacaga ggcaaaaagg aggataatat gaatgatgca
    23761 acagaattag caaaagagct taaagaaaaa gaatttagtt ttcaagaact agttacggat
    23821 atacagaaaa aaataaagaa gcaaaatcat gaattgaatg cgtttgtcgc gcttgaacca
    23881 ttcgagagta attcccacga gctattgatt ccccagtcag aaaaagggcc attggctggt
    23941 atcccatttc ctttaaaaat gctcggtcaa gaaaaaaagg gatggctagc tacttcagga
    24001 tctcgtttat ttgaaacaca ccgagcttct catacatcta attatgtgcg gcaagcagaa
    24061 gcgataggtc tagttccttt tggacaaacc aatgcgccag agtttggttt caaaaatatt
    24121 acagacccag tcatctatgg cccagcaaga aacccttgga accttgaatg tacaccgggc
    24181 ggatcaagtg gaggagctgc tgctgcagtt tcatcaggaa tcgttccttt agctggtgct
    24241 agtgatggcg gtggttctat tagaataccc gcttcgtttt gcggattgat tgggctgaaa
    24301 ccttcgcgag ggacgatgcc agttggtcca tatgcttgga gaggatggca aggagctgct
    24361 attgatttcg gcttgacagt ttctatgaga gacacggagg ctttatttta tgggatgaga
    24421 agtatccatt ccggtgcgcc atatcaagta tcgccagttg agtggcaaac acatccaaga
    24481 aaaaaacggt tgaagatagc tttttgtgtt gattcaccga tccactcaca gattagtgaa
    24541 gaggcagtac ttgctgtaaa aaaagctgta gatttccttg gaaaagaagg gcatgatttg
    24601 acagagattc cttacccact agatggtcgt aaactgatca cgtcttatta tcagatgaat
    24661 ggcgcagaaa cagcagcaat gatccgctcg attgaaacag gcatccagcg agctgtcaga
    24721 aaagaagaac ttgaacccat ttcttggact ttgttccaat atggtcagaa gctctctgcc
    24781 gctacttaca tcgattctct gcatgtatgg gatgaagcag caattgtcat ggaaaaccta
    24841 catcaagaat acgatctatt cctttcacca acgactgcat ttaccgcccc taaaatcagc
    24901 gaagatttgc aaagtgatgc gataagagca cagatggaac acatcagtga ttgttctgaa
    24961 gtagaaggtt tagacgttgt ttcttccatg tttgaggaga gcttgaagat cacaccttat
    25021 acacagttgg ctaatctgac tggacaacca gcaatcagct tgcctactca tttgacaaaa
    25081 gaaaacatgc ctctaggaat ccaatttatg gctgccagag gaagagaaga tttgctattt
    25141 caaatcggct atctatttga agcaaatcat cagttccatt taccaaatcc atggaaatag
    25201 cagaaacaag gagaagaaga atgaagaaaa aaagattgtt tgctctaata actagtgcct
    25261 tttttatttt aagcgcttgc ggtacagctg ccgctaatca ggaagataac agctggagta
    25321 atgtagaaaa aaagaaagaa ttagtagtag cgacttctgg cacactgttt cccgcatctt
    25381 attataatga tcaaaatgaa ttagttggtt atgatgtaga tttggcaaaa gaggtggcta
    25441 aacggttaaa tgtcaaaatc tcctttaaag aatacaacgt ggatggacaa atcacttctg
    25501 tttcaaaaag agaatcagat tttgctgcga acgattttgg tatcacaaaa gaaagagaaa
    25561 aaaaattctc cctttcagag actttcaaat attcatttga cagtatgatc gtacgaaaaa
    25621 aagatgattc aggaatccac tcacttgaag atcttaaagg gaaaaaagca gctggcgaac
    25681 ccaatactag ctatatgcgt ttagcggaaa aacacggagc taaattagtc acatatgaca
    25741 atgccacgaa tgatcagtat ttaagcgatg tagcaaatgg tcgaacagat gttattctaa
    25801 atgattatta tctgcagaaa atggccgtat ctgctttacc agatatccct gtaaaaatac
    25861 tggagaacgt ttatttcaat gaaaacgaaa gtggtttttt attgaaagaa ggaaatgatg
    25921 ctctgaaaaa gaaaatcgat ggcgtattaa aagagatgaa agaagatggg acgacaaaga
    25981 aaatatctga aaaatatttt caaactgatg tttcagtcaa accgaaagaa acgatggctg
    26041 agtcggtgag tgagtgatgt actttcccct aattgatttt tccctcatgt ggacttcact
    26101 tcctttcgta ctgcaaggct tggtatacac attagggatt ggcttcgtgt cgtttctttt
    26161 aggaaatttg gtagggttgc ttttgacagt tttaggtctt ttggattggc tgcctctgaa
    26221 tgtatttatt cgtttttatt tatcgttctt tagaggcatt cccgcactag tcctgctgtt
    26281 tctgttatat ttcgggttac cttatcaatt aagtgcctta acggcttcag tcatctgctt
    26341 tacgattacc agcagtgcat ttattggtga aatctatcga ggatcactag caggcgtttc
    26401 ttcaggtcag tgggacgctg gtttagcttc tggtttttct ttctttgggg tattgaaata
    26461 tatcgttttg ccgcaagctt ttcgaatctc agtaccggca ctcagtaacg tagctatgga
    26521 tctagtgaaa ggtacttcgt tagcagcaac aatcacagtg ccagaaatat ttcaaaaagc
    26581 aaagatcata ggcggtcgga cattcgatta tttttctctc tatattttag ttgcactgat
    26641 ttattgggtc atttgtatcg ggatcgaaaa agtgcaacag tatttagaaa aacgttctat
    26701 ccatcagtca atctgaaaaa tagaaatggt gctagcgtgg ctggcaccat ttctattttt
    26761 tgtttcttgt atattctgcc tagtatttta aaaccatttc atgtaaaatg taaatcgaaa
    26821 atatgttcgg aggtagaaaa catgaagacc ccgctaacca tcgaaataga atcctcgtta
    26881 taccaatatt gcatcgagca aggcggcttg gttgtagaag aagtcacgat gcctgatgac
    26941 caaggaattg tagatacgct tagctgcttg acaaaatttg atggaagccg agaatggcga
    27001 tgctatgagc tgaaagtgac aaaagcagat tttcgctcta cagccaaact gtcatttgtt
    27061 ggacattata attattttgt tttaccaagt aaactatatg aagaagtaaa aactgaaatc
    27121 cctacaggaa taggtgtttt agtgtatcgt ccgtacacgg ttgaagagga gatgcctgcc
    27181 tctggtacat ttctgattgc gaaaaaagca gcaaagaaag agcttgctgt accggaagaa
    27241 gctttgacaa accgcttcat ggcttcttta ttcagggaag taagaaaagc aaagcaaatg
    27301 gagcgaggcg taaaatattt tccaaaagat caattgtaca aagaattgaa aagacgttca
    27361 gaaaatcaag atccattttc taacgaacga tattatgaac ggtttttaga ggaaatagct
    27421 agtcaggcaa tcaatgagtt gcaagaagaa gttatcgcgc ttcagcatga ttatgaatat
    27481 ttgaggcaac aacagcagat ccgtcggttg cctacagagc cattggagtg aaaaatatgt
    27541 actatcctta tttaagagga aaacaatttg acctattagc attaaaagaa gcactgtcgc
    27601 gaggattgct ctccaataaa atccaaccag tgatcgaacc agtacgtgat tccgctacgc
    27661 ttaaaaatgt gatcgaatta tttcaaaaaa agcaccatcc aatcgctgtg atccaaaatc
    27721 cccaagtagg acaattcaaa ttattcgatc agcatgtgca cagttggaca gtcaaagaaa
    27781 atagctctgt cgtccctgca cagatcttaa cgccagaaaa tctcagtgaa gtactggatt
    27841 cacctccagc gtttcttgtt ttcgatggac agcactaccc aaaagataca gaggtgtgga
    27901 aacagttggc aggagttgat tcgaaatttt tgataccaga tactagtcgc tttcgcatct
    27961 ggctgcccga aaacaaaatt gtgatccgtg actcttttca aacgagaaag catgttgaaa
    28021 gttatgcaga taaaacagat gactttttta gtgatgacta tctttttttc cacgcagacg
    28081 gatatattgg attttctgat ttcacgatcg aaggtagccg ttatttcgat aaagggttcc
    28141 ctagccgagc gcttgctatc catctaacgt atattgatgc ttacggcaat atacgcgtga
    28201 aacattttgt ctctgacagt aacgactctg ctaaagacca agcattgaag tttcttgaag
    28261 caggagataa aatgaaaaaa tggatcatgc gtcaccatca tcaactcttg attacttcag
    28321 gaatgattga attattggct ctttaccagc aacaaaaatt ccctggactg ggagtgttga
    28381 aaaagtggtc acttatgcat catttggaac ttattagtca cctgctagat catccaaaag
    28441 attggcttaa atattattca aaagttcagg aactatatga agtgatccaa tgattagata
    28501 atgtaaatga aaaaggaata gaaaagagga aactggatgt atattcggca aacaaggaaa
    28561 gaagaagtag aagaagtggt agaaatcatt aatgccgcag cggatttcat tgcttcgcaa
    28621 ggctctcctc aatggcaaaa cgggcagaaa ccaacaaaag aaacgatttt gaacgatatt
    28681 gaaagaaaag aaagctatgt attaatagtg gaagatcaaa ttgctggaac agctgcatta
    28741 gtctcaggcg tggatcccgt ttacacaaaa atagatggta gttggaaaga atcaactggt
    28801 ccttatttat cgattcatcg tgtcgcttta gcagaaagta ctcgaggaaa aaaactagca
    28861 aaaccgttct tagaacattt gttgacgatt gcagccagca aaaatatcca agatatccgt
    28921 atcgatactt atccagctaa tgaaccgatg gaaaagacca tctattctgc tggattcact
    28981 tatcaaggga tgattgaatt tccttttgaa cacggcgaaa gaaaagcata tcaaataatc
    29041 atcaattgac tataaaatca tctgagcaaa gataaagaca ttaacactac tgaaaaaaac
    29101 aatcatatga tagccaagag gttgtaacag aagtggccag cttcaaaaaa caagaaagaa
    29161 tttccgaaaa tgcttctcaa atttttgtgg aattttagcg tattttacga aatagctgct
    29221 ttctgaaact cccttcatcg agaggtcgtg acatagcttt tgtcacgatc tctcggctta
    29281 tcctacgagt attattcgat acatttatat caataatcct ttttttattt tatctgcagc
    29341 ttcttggaac gctccatcgt ttgacacgac taaaagtgag gggatagctt tcaaacgttt
    29401 caactgtgct aaatcttcta cataaaccgc cagtctggct gaaatctgtt cagatgaatc
    29461 tccacgtttt ttcaggcgcg attgcaatgt ttctttagag atcgtaataa agataggacg
    29521 gactaccgtc ccgaaatact catataaatg ccaaaaacca tttgctgtca aaacggcgta
    29581 acaatttcct actgtcagtt tctttttaat ttctgcttta ctggaaccat atttatgttg
    29641 agcatattgg tcccactctg caaactcatt tcccttgatc atctgattga atgtattgtc
    29701 agaaacaaaa taataatcct cttgatcttt ttccccaggt cttggtgatc gattcgtgta
    29761 agtaatgatc ttttgttccg gctgaaaaat agcttctgcg agtgaagttt ttccagaacc
    29821 agaaggaccg ataaatacat agcaataatt cattgtcatt tctcctttga tgattgaaca
    29881 agtgaaaaag ctttggaaaa tatttccaaa gcttttaaaa gtaactttgc ttttttgtat
    29941 tttataccag caagccagtc acaatagcac ttaaaaagct gactaaagtc gctgttagca
    30001 aaattttcaa tccgtgtttt gcgacaagat ttcctttttc ttcatttaat cccttcatcg
    30061 caccagaaat gatcccgata gaagagaagt tggcaaatga aacgaggaag acagatataa
    30121 ttgctgttgt acgctcagta aaatggaaat taccatttgc taattctgtc atagcaacaa
    30181 attcatttgt aaccagttta gtcgccatga tactaccggc atccactgct tctttccatg
    30241 ggattccgct gatgaaggca agaggggcaa agatgtaacc taggatctct tggaaagtga
    30301 tgccgaatat cccgtggaag atagcattga tcatggcaat caaagcaaca aaaccgataa
    30361 gcatagcagc aaccgtgatc gccacatgga aaccatcaag aatgtattct cccaacattt
    30421 ggaaaaatgt ctgttctttg ttttcttcaa tgatcagctc atcttctttt tcttctaata
    30481 catagggatt tacaattgaa gccagaatat aaccgccaaa taagttcaaa acaagggcag
    30541 tgatcacata tttagaatcg atcagtgcca tataagatcc gacgatcgac atagaaactg
    30601 tagacatagc cgatacactc atggtgaaca aacgtttctc agataggaag ggtaattcct
    30661 tttttatgga aataaaaact tccgattgtc ctaaaatagc agaagctact ccattataag
    30721 attccaattt gcccatcccg ttgattttac ttaatcctag accaacagct ttcataaata
    30781 atggaagaat cttgatatag cgtagaatac cgataatagc agaaataaat acaattggca
    30841 tcaatacgga aagaaagaaa ggtgcacttc ctttatttgc tacaccggca aaaacaaagt
    30901 caacaccttg cccagcaaaa gcaagaagat gatcaaacat ttttgccaat acagaaacaa
    30961 ccgctgtacc aaaagttgta cgtaataata cgaaaccaag aacaagctgt aaaacgaaca
    31021 tcacaattag tggtttcaat ttgattgctt ttttgttact gctgatcaaa aaagcaagcc
    31081 ctaatgtgac aaataaacca ataataccta ataaataact caaataatca ctcctattcc
    31141 aaattccgtt ttattttacc tgttttgcaa ataaaatact aatctttagt gaaattttca
    31201 ttactttttt agagtgaaac gcattcattt tccattagaa aataaagcga acaaaataaa
    31261 aggtttaaaa agtgtaacgt cttagtaaag tctataaaaa aacgaaacta tcgattaagc
    31321 taatagtttc gttttcaaca tttataagta aactttttct attggtaata tagattttcg
    31381 gaagggtaga caggtgcgca ggtaatatcg attcctagtt ttttcaatgt ttgttcatca
    31441 tttttattga ccatcacagt agagtgggct tgtgctccct caagttcagc tagtttatca
    31501 taagcaactt gagcgattgg attcgttact gcactgattg ataaagcgat caagacttca
    31561 ttgatgctta gtgcatccaa agaggaatga agtgtctttg atttcaatcc ttgtattgtt
    31621 tcaagaacta atggtgacaa taaaggaatg tcatctgcga tatgggctaa atgttttact
    31681 gcatttaaga taactgccgc tgacgcatcc atcaatgaac ttgtacgccc ggtaatgatg
    31741 acttcatctg gtaattcgat tgcaatcaca gcagaaggat cttttgtagg actttgcgct
    31801 tgaatcttat ctgcatagtc atgggcaggg actaccacgt ttcggtcttc aggacgtaaa
    31861 ccgacttctt ccataatcag tttgattcga ttaactgctt cttcgtcgat caatcctttt
    31921 ttgaagtcgc attctgtttg gaaataacga cggatgattt cttgtttaga ggcttcttgg
    31981 acaacggtat catccacgat cccaaatcct acacgattca cacccatgtc agtaggagat
    32041 tgataaacag attctttacc agtaattttt tcaataatac gtttgattac aggaaatgtc
    32101 tcaacatccc gattatagtt cacagctact ttattgtagg catcaaagtg gaaggaatcg
    32161 atcatattga catcttttag atcgactgtg gctgcttcat aagcaatgtt cagcggatgt
    32221 ttcaacggaa cattccatac tgggaaagtt tcgaacttgg agtaaccagc tgcatgtcct
    32281 ttttggcttt catgatacag ttggttcaag caagtagcga gctttccact tcctgggcca
    32341 ggagctgtca ctacaacgat tggtttagtt gtttcaatat actcattttt tccaaaacca
    32401 tcttctgaga cgattttttc tacgttgact ggatagtctt cgatttctga gtgtttatag
    32461 accttgatgt ttcgtctttc tagtttattg ataaagactt tcgtggcagg ctgtccacta
    32521 tagcgagtga taacgacact gttgattaat aagccataac cacgtaattc atcgattaac
    32581 cgcaagatat ccatatcata agtaatccca taatcaccac ggatcttatt acgttcaata
    32641 tctccagcat agacgcaaat cagtatttca gcttgatctt tcaatttttg cagcaatttg
    32701 attttcgcat cttcttcaaa tcctggaagt acacgtttcg catgcttgtc gtcaactaac
    32761 ttcccaccaa attctaaata taatttgtca tagtggttca ctcgttccaa aatatacgct
    32821 gactgctctt caatatattt ttctgaatca aaaccaattt ttttcactag gttccctcct
    32881 taagtactaa agcatttttt catttttttg aggattcgtc aactggaaga gcgaaattcc
    32941 tcaaaaaaac aaagaaaatg gtttaaacca acttgtctag atagttattc attggtatga
    33001 tagtttttga taaggaaggt gctacatgaa aaaaagacag aaaaagaaaa acgcatataa
    33061 acactatatc cgttcgattt ttaccggtta tgaaagaatg cttgaagatc ccgaattgga
    33121 acaattgacg tttacttatc taaacgaaga aacgcagcta actcgtgatg agcatcagcg
    33181 cattcatttc acaacaagag atctgcctag taaataaaaa ataagataaa ggtcatcgga
    33241 ttcgattctg tcctatcaga tggaaagact agttgatcga aaaaaaggct gtaccaaatt
    33301 ttggtgcagc ctgttttatg gagcattgcc cgctcttttt tataacaatt ttttacagaa
    33361 aatggtacta ttgaagtatt aataagtgaa aaacagatga gtaagaggag gcaagtagta
    33421 tgaaagagcc agatacaaat gcaaattatg agccagacga actagaggag acgaacgcgg
    33481 atcaggatac aggacaagaa tcgtcttctt tttacgatat caaagaaaaa gcaagcatga
    33541 atctttccca attattagaa gacttacagg cttttgaaaa agctgtccgc gaagaagata
    33601 tccctgagat ctaccgttta tacaatggcc gattgaatga agaattaaaa agaagctcaa
    33661 atgaaaatca cgagatcgat caattgctga tgcgtaagat ccatgatcgt tttttacagg
    33721 aatttccttt tatggaacaa gtagaaaaca tctcgccaac gatgagctat tacaaaatcg
    33781 gcacttatta ccatgatcgg cccacggtcg gtattgatgc aagtctgcca gaaatttttg
    33841 ttttgcctaa gatcgatgaa gagtgggaga aatattccca accggagtca acggactatg
    33901 acaaaaaaat caatgagcta gacgcaaagg tgatcactgc tcagacagaa attgaacgtt
    33961 tagatgaaca aataaaagaa atcaatcgac aaatgactga tttgaacgac aataaaggat
    34021 tcttgaatcg taaaaaaatc gaggaagaaa ttcaagaatt agagaagaag aagcaagtac
    34081 tatctaatga aaaattaggc tggcttcctt atattgagac gcctgaaaca atccagcagc
    34141 aaaaagaagc attgaagcaa gaagcaagag cagaccagct tcgtgcagcc atcgtagaaa
    34201 aagaacaaag gcaaatcaga cgctatttcg gtagcaaaga gggattcggt caagcaatcc
    34261 atgaattctt gatgaattat cttggcaatg agaatcctaa taatcaatct aatgaaggag
    34321 gttccgagta tgaatgaaca cgatgaagca gaatggacaa aaaatgaaga acaaacagaa
    34381 gatcatgaag aaacgaacac ttcattggaa gaacaaacaa gtaatcctct ggatgacaca
    34441 gaagaaatcc ctatgctaga ggaaacaaaa atacatgaaa aagaaaaagt aactccgacg
    34501 aatacgaata ctgcagaaaa cacccatgct tacgaaataa ctgaaaatcc cgggtattta
    34561 gaaggaaaag agcaagatca tcaagatatc gtcagtttga ttgaaacagc ggaagcagaa
    34621 ttagcggatt tacgtatgag aaaagatttg atcgaatcag attttccaca attattagaa
    34681 tcatatgatc gttttatatt gaatgaagaa ccaatctcca cgatcggaaa gacaagcctg
    34741 atcgaatact tcacgtatga attactgaaa ccgttgaatg atattggtct ggaacggtca
    34801 aattcagctt atgacacatg gaaaacaaga catttttcga tcaattatac gttgaatgga
    34861 caaaacgaat tagtcttttc ctttgtatta ccgaccatcg atcaacgata ccaagtggaa
    34921 tcgatgagtc tcctaaacgt atcaccagag acaatggaaa tcaatgtcca agatgaccgg
    34981 gtgctttctt tgatccgaca ctggtcagtg gatcgagtat tctctgcagg gcagatcacg
    35041 atattcaatc acaaattgaa tcaattatta gcccatgcaa gaacacttgg ttttaccgtt
    35101 aatcagacat tactagacaa tacgaagcca cttcgtttga atcttcagag cgaatttgaa
    35161 ttgacgaatg aagtattgga tgatattttt atcgtggcaa tgaaaaatcc atcctacgat
    35221 atggaaaaga tcaacgaaac tacttatcaa gtacgattag ataaaggaca gtctttaacg
    35281 ataacaacaa acgaaaaaga tcaaacagtc ttgtcgatct catctggaga ctacccacga
    35341 tctgtcattg atttctttat caattacgaa ttcttggtcc cattaatggt gagaaagtcc
    35401 tgattggata agttggatta ccagatgtca ttcagataat tctgttccaa aggacttgcg
    35461 gcagttatcc agaataattg tcacaagtct tttctgtatg tactaaatgg acgtgaataa
    35521 cttgctgatg aaggagggat ttcattagga atgtccacaa ataaaatagc acagcttagc
    35581 ttattgtctg ctgcttgtgt agcaggtagg atcgcttttc aatttattcc gaatttccag
    35641 ccaatgactg ctattttttt atttatagta ctttacttaa gcttaaaaga tgcgttaatt
    35701 gtcatgagtc tttctattgc gatcagcagt ttttattttg gtgttggacc atgggtcatc
    35761 ggccaatgga tcagctatac tgttgttctg agtttgtttt caatcgtctg cttgagaaaa
    35821 acagtgcaaa ggaatctatg gttaaaggga gtctgttttt ttctggcggg catggtttac
    35881 ggaataggta tgaccgtttt tgatacgctg ttatatcgtt tgcctcaacc ttggatctat
    35941 taccttcaag gggtgtcgtt tgatttgatg cacagtatag gcaatgttgt gttctttctt
    36001 gtttttctgc cagtcgtcaa acgtttttac aatcattcag gaggaaaaaa tgaaaaaaat
    36061 aatttatagt ttgcttgcaa tgagtgtcag tatactcatt ttgacaagtt gcagtacaac
    36121 ctatacacaa tcggcttcca accaaaagga ggaagtaaaa acatcgcaaa aagcaacaat
    36181 cacgttacaa gaaaatggtc aaaacttttc ggaaaaagaa gtggtcttca aaaaaggcga
    36241 tgatttactg agtattttga aacgaaattt tgaagtcaaa gaagataacg gcttcatcac
    36301 ttcgcttgaa gggcactcac aggatgagaa aaatcaactc tattggatgt ttactgtgga
    36361 cgggaaaagt gctactactg gtgccaaaga gatcaaattg aatgatggac aatcggtcat
    36421 tttcaatttg tctaaactat aagtttcata aaaaactgtt aaagggcgaa tattgccata
    36481 attcagtgag ttcagttgat gaaagaagga aaataacatg gaaaatttta aaaaaagcgg
    36541 aatgttttcc gtaattgctg ctctaggggc taatattcta gttgctatca gcaaatttgt
    36601 cggctatgca atcagtggca gtgccgccat gctaaacgaa agcatccaca gtatcgttga
    36661 ttgcagcaat cagattttgc tgttattcgg tgataaacaa gccaataaag gacagagcga
    36721 gttgcatcaa tttggtgaag gacgagcaaa atactttttc agtacaatcg tcgcaatgat
    36781 gcttttcttc ggcggtgggg cacttggggt gatggaagct tttgaaaagt tgacgcatcc
    36841 atcccatgaa gtgggtaatc cgatcattgt tatagcaata ctgttatttg gtttggtaat
    36901 cgaaggaagt tcgttacgcg tggcaatgaa agaaatcaaa gaattgaata ctgaaaaact
    36961 ttccacgatg cgctttttgc gcgaaagtcg acacagtgaa atactgatta tttttacgga
    37021 agacttgtgt gctgtaatcg gtttggtctt ggctttagca ggaacaatat tgacttatgc
    37081 aaccgggatt gctgcatttg atgcgatcag cggattgctg atcggtttct tgctgatggg
    37141 agccgccatt ttcctagcaa aagaatttta tagtctgatc atcggtgaaa gcgtgacagc
    37201 aagcgattta tcaaaaatca agttagcttt tgaacgtcct gagatcagtc ggctgatcga
    37261 tataaaaaca gttcatttaa gtccaacgga gattttagtt gcagcaaaag cagatatcgt
    37321 tggtaacaaa gagaatgaag cttactcggt catcaatgat attgaaaaaa atatgcgtca
    37381 gtctcttcct gacaagaaga tgtatatata cattgaaaca gataaatatg acccaaatta
    37441 ttctcgtaaa taaaacgttt attcatgaat tgaagcaaaa atgagaaaaa tataatcttg
    37501 tttttaaata aaacggctac aatttagcga atttatgtta caatgagtcc gctgtttatt
    37561 tgttgtaatt aaaggagata ttttaatgaa caaaaagaaa agtgcgccat ggcttcaagc
    37621 tttgcatgca gtgatgccac tttgtataag ctatatacca gtaggattag cttgcggagt
    37681 attgttgcaa aaagttggat ttgatcctct cttatcagga ctgttatcga ttctggtctt
    37741 ttccggtggc gcgcagtttt tagttgcatc tatgcttacg acgcaagcat catttgcaac
    37801 gacattattg atggttttct ttttagaatt acgctataca ttattaggag caagtcttgc
    37861 cggttttatg aaaaaagaaa agcggacgtt tttggctgtc ttttctcaat cactgaatga
    37921 tgaaaactat gcggtgaact acttaaagtt ttcaactgac ccttcctgga ataaaagaaa
    37981 ggctttatat gtcaattggt tctcaatgac tgcatgggcc ggtagcaata tgatcggtaa
    38041 ttttttcggc tcggtgattc gagtagatgc tgaccttgtc cattttgctt tgacggccat
    38101 gttcattttc atgtttatca tgcagatgaa aagcgcacta ctgatcttta caggtttatt
    38161 ctcaggcgta ttaggggtcg tattcatggt attattccaa aatactttcg gattgattgc
    38221 agcaacagtc attgcttcat ttgccggatt tatgctggag aaggcattca aaaaagaaaa
    38281 agctaagaaa ctaagagacc gcggtaaaga tgtcaatgag ccgctcttca acttcccgga
    38341 acaggaggcc aatcaccatg actaaactat atttgctact tttagttgct tgtctgttca
    38401 tcgtggcata tatcccgcgc ttgttcccga tgctttattt tactcatcga aaagtgccat
    38461 cctggttcag tgactggatg aaatatgtac cggtggcatt atttgcggcg ttagctttta
    38521 aagatgtttt cattactcat gaacatctgg atattgcttg gaatatcaaa atagctgcaa
    38581 tgattctagt agcaggcgtg gcttacaaaa cacgttcgat ggcgttgtca gttttgacag
    38641 gacttgcgtc tgtctttttg ctgtctatgc tttaaactgt tttattttat taaaaacaga
    38701 gattgcgaca taagttgttc aaactgatct atccgaactg catttgcaac agtcaattct
    38761 ggatgcaagt ttattcgtag ggataaaaaa gattagtgtt ggcttatgat gcaagctctt
    38821 ttttatttta ggaattagag agggatttgt ccttctatga ttttttgcta taatagggaa
    38881 gatgtttatt ttatgaaaga atagttgagg gaatttaaat gaataaaaaa ttgatgcaag
    38941 gaacattttg gctaaccttt gctaatcttc tatgtaaagt tttaggggta gtctatttga
    39001 ttccctggct aagtatgatg gggaacaatc aagatggtat gcttgctacg acattgtata
    39061 atgttggcta tcttccttat ggattgttcc tgatgcttgg tacagtcgga tttccaaatg
    39121 cgattgcaaa aaaagtagct gtagccacaa aagaaggaga taacgctgct tgtcggctga
    39181 tttttagaag tacgatcaat atcatgtttg tcatcggtat cgcctctgct gcactgatgt
    39241 atttatttgc tcctttacta gccggaatca gtccgattgc taacgttaat aatgggatac
    39301 tagctatcag aagtttatgc ccatctttga ttgctatccc aattcttagt gcaatgagag
    39361 gatatttcca aggaaaaaat gatctgcggc cttatggaac ttctttgatt atcgaacagg
    39421 ctgtgcgagt gatcgttatc ttggctggta cttattactt gcgcgtattg actgacggaa
    39481 ccatattaga agctgtattg atcagtacag tcgcttcttt cttcggtggg ttagctgcga
    39541 ttatccatat gtatatcgtc ggacgcagaa aagacttctt cgaacttaaa gattttttga
    39601 tttccagccg ttatttcgaa agagaaaacc gatctgcctc tgtctctatc attcgggaaa
    39661 cactaccgtt tatttttgtc ggctcagtca ttactatcgt tcaaatgatc gaccaagtaa
    39721 cgatgaaacc actgcttcac tttttccgtc cagagatcgc agatcagcaa ctggaattct
    39781 tattcagccg tgcttctgtc aatccaaata aattgacatt gatcctgatc tccatggtag
    39841 gaacagtagc tataagcagc ttgccaatat taagcacgat gaagaaaaaa gatcggatac
    39901 aaatcgaaaa aacagtagga gatagttttt cgattgcgtt attgattctt cttccttcat
    39961 tgactggaat gtctttatta gctggaccac tatacacatt gttttttggc tatgatcctg
    40021 aaagtgtcgg atatttccaa atggctttgc tagcttcttt gtttttctct ttattcacga
    40081 tcctatctac gatgcttcaa tctttgaatc accatcgttt tgcgatccga ttaactgtag
    40141 aagcaattat cctgaaagtc atcttccaag taatcggatt aggattagtt ggcggatacg
    40201 ggatgagctt atcaaatggc ttagcattcg gtattgtctt tgttcgcggc tatcacttta
    40261 tgtgcaaaga ataccgaata gcacctttag caaagatcag caattttttc ttaaaaactt
    40321 tccgctccac cctgattatg cttgcagtat gttttgccgt tttctttttg ctgaatcagc
    40381 gattgtcaat ggaatcaaaa agctatgcaa tgatttattg tgtggctgta ggaagtattg
    40441 gcggcttagt atttttattt tctcaattcg gaaaaaatgg gtttcgaatg ttgaaaaatg
    40501 ttaaacatca tagcagaagc aaagaatagg ttaactaatc gttttttgct gtcacttgaa
    40561 aaacggcaac tcgtatgatt acgcttgtcg tttttctatt ttccaatttt agtttcatat
    40621 ctaatcttac ttatgatata gttataaggt ctggaaaaat tctttgaaac gaggaaatta
    40681 aacacatgaa acttgcagta gttacagata gttcggcata tctgccggaa cgtatcaaga
    40741 accatcccga cttattcgtt attccaatcc ctttgattat ggatgggaaa atttataacg
    40801 aaggaatcga tatcgaagcg gatgaatatt atggactttt aaaaaacagt aaagattttc
    40861 ctactacttc acaacctgtc gtaggggaag ttttgggttt atatgaggaa ttgaaagaga
    40921 aagggtatga cacgatttta agtatccatc tttcttcagg gatttctggc tttgtcaaca
    40981 cattatttgc gatgaaagat gacatcagcg gagtaacggt cattccttat gactctaaga
    41041 tcactagtat gccgatggga cacatggtag aagctgcctt agacttaaat gatgaaggtc
    41101 agtcccttga tgaaatactt gcacatatcg atcgaatccg agataatacc tatgcttatc
    41161 tgattgtaga tgatttgaac aatttagtac gaggaggacg tttgacaaat ggtgcagcgc
    41221 tgattggcag cttattaaaa atcaaaccga tcctgacatt ttctgaaggg aaaattgttt
    41281 tattcgaaaa aatccgttca agtaaaaaag catttgctcg agctgaagaa attattggta
    41341 gaagaaataa cgaaatacaa ccgccagtca aactttacgt gatacatgca aataatttag
    41401 aagtagcgat tgcggagaaa gagaaattgc agaaaaaata tccaaatgca gaaatcgaaa
    41461 ttggtcattt cggaccagtc attggtacac atttaggtga aaaagccatc ggcattgcca
    41521 tttcagcgca ataattcctt ttattcaaaa aacataccaa aaata
//
LOCUS       DADLIO010000017        41482 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.017, whole genome shotgun sequence.
ACCESSION   DADLIO010000017 DADLIO010000000
VERSION     DADLIO010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41482
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.017"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            214..498
                     /locus_tag="JOX41_001050"
     CDS             214..498
                     /locus_tag="JOX41_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HAY6448809.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(779..1198)
                     /locus_tag="JOX41_001051"
     CDS             complement(779..1198)
                     /locus_tag="JOX41_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HAY6448810.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(1200..1784)
                     /locus_tag="JOX41_001052"
     CDS             complement(1200..1784)
                     /locus_tag="JOX41_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HAY6448811.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(1831..3306)
                     /locus_tag="JOX41_001053"
     CDS             complement(1831..3306)
                     /locus_tag="JOX41_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HAY6448812.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            3487..3798
                     /locus_tag="JOX41_001054"
     CDS             3487..3798
                     /locus_tag="JOX41_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448813.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(3913..6249)
                     /locus_tag="JOX41_001055"
     CDS             complement(3913..6249)
                     /locus_tag="JOX41_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAY6448814.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            6391..7059
                     /locus_tag="JOX41_001056"
     CDS             6391..7059
                     /locus_tag="JOX41_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAY6448815.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERVGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            7062..8105
                     /locus_tag="JOX41_001057"
     CDS             7062..8105
                     /locus_tag="JOX41_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAY6448816.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(8342..9223)
                     /locus_tag="JOX41_001058"
     CDS             complement(8342..9223)
                     /locus_tag="JOX41_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAY6448817.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            9382..10110
                     /locus_tag="JOX41_001059"
     CDS             9382..10110
                     /locus_tag="JOX41_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HAY6448818.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            10266..10583
                     /locus_tag="JOX41_001060"
     CDS             10266..10583
                     /locus_tag="JOX41_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAY6448819.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            10576..11184
                     /locus_tag="JOX41_001061"
     CDS             10576..11184
                     /locus_tag="JOX41_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HAY6448820.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            11200..12030
                     /locus_tag="JOX41_001062"
     CDS             11200..12030
                     /locus_tag="JOX41_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HAY6448821.1"
                     /translation="MRLKHFLITGIGLMLTGGLLAGATYTLGAQKSLTWDNGPRLIDM
                     VTETKKIKDANKIVIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKK
                     STGAIISLEDTSAQITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSF
                     NEFTGGTITAKDELGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSL
                     HEMENSGYTIQTSGESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD
                     "
     gene            12168..12656
                     /locus_tag="JOX41_001063"
     CDS             12168..12656
                     /locus_tag="JOX41_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HAY6448822.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            12707..13579
                     /locus_tag="JOX41_001064"
     CDS             12707..13579
                     /locus_tag="JOX41_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HAY6448823.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            13755..14117
                     /locus_tag="JOX41_001065"
     CDS             13755..14117
                     /locus_tag="JOX41_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAY6448824.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            14126..14878
                     /locus_tag="JOX41_001066"
     CDS             14126..14878
                     /locus_tag="JOX41_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6448825.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            14892..16694
                     /locus_tag="JOX41_001067"
     CDS             14892..16694
                     /locus_tag="JOX41_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAY6448826.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            16971..18011
                     /locus_tag="JOX41_001068"
     CDS             16971..18011
                     /locus_tag="JOX41_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAY6448827.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(18063..20207)
                     /locus_tag="JOX41_001069"
     CDS             complement(18063..20207)
                     /locus_tag="JOX41_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAY6448828.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(20564..21937)
                     /locus_tag="JOX41_001070"
     CDS             complement(20564..21937)
                     /locus_tag="JOX41_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAY6448829.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(21937..22332)
                     /gene="rbsD"
                     /locus_tag="JOX41_001071"
     CDS             complement(21937..22332)
                     /gene="rbsD"
                     /locus_tag="JOX41_001071"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002829567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HAY6448830.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(22360..23277)
                     /gene="rbsK"
                     /locus_tag="JOX41_001072"
     CDS             complement(22360..23277)
                     /gene="rbsK"
                     /locus_tag="JOX41_001072"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HAY6448831.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(23385..24398)
                     /locus_tag="JOX41_001073"
     CDS             complement(23385..24398)
                     /locus_tag="JOX41_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAY6448832.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(24479..25078)
                     /locus_tag="JOX41_001074"
     CDS             complement(24479..25078)
                     /locus_tag="JOX41_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAY6448833.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            25264..25965
                     /locus_tag="JOX41_001075"
     CDS             25264..25965
                     /locus_tag="JOX41_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6448834.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            25975..28686
                     /locus_tag="JOX41_001076"
     CDS             25975..28686
                     /locus_tag="JOX41_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAY6448835.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            29137..30765
                     /gene="treC"
                     /locus_tag="JOX41_001077"
     CDS             29137..30765
                     /gene="treC"
                     /locus_tag="JOX41_001077"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HAY6448836.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(30825..32006)
                     /locus_tag="JOX41_001078"
     CDS             complement(30825..32006)
                     /locus_tag="JOX41_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAY6448837.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            32258..33781
                     /locus_tag="JOX41_001079"
     CDS             32258..33781
                     /locus_tag="JOX41_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HAY6448838.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(33850..34578)
                     /locus_tag="JOX41_001080"
     CDS             complement(33850..34578)
                     /locus_tag="JOX41_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAY6448839.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(34591..35871)
                     /locus_tag="JOX41_001081"
     CDS             complement(34591..35871)
                     /locus_tag="JOX41_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAY6448840.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(36012..36614)
                     /locus_tag="JOX41_001082"
     CDS             complement(36012..36614)
                     /locus_tag="JOX41_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory regulator AgrB"
                     /protein_id="HAY6448841.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            36859..37065
                     /locus_tag="JOX41_001083"
     CDS             36859..37065
                     /locus_tag="JOX41_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448842.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            37377..38096
                     /locus_tag="JOX41_001084"
     CDS             37377..38096
                     /locus_tag="JOX41_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAY6448843.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(38177..38860)
                     /locus_tag="JOX41_001085"
     CDS             complement(38177..38860)
                     /locus_tag="JOX41_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HAY6448844.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            39078..41264
                     /locus_tag="JOX41_001086"
     CDS             39078..41264
                     /locus_tag="JOX41_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAY6448845.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
BASE COUNT        13464 a         7347 c         8321 g        12350 t
ORIGIN      
        1 aggaagaggt tgtgagcctg ccgtttaact ctgagtcaca aggagcaatt tcaaaaaaca
       61 gcttctcatg tttgttgact attgtgactt gtgaccgagg agttggcagg agaacaccgt
      121 ttattcgaaa aaaggaactg cgacaagact tttgtcacag ttccttcttt tttttgctat
      181 gctatactag atgtaaaaaa taggagaaat aaaatgaggg aaatttattc ttttgaatca
      241 aaaatctatg cttccgaagt cggcaagggc ggggcatata ttatttttcc gtatgatata
      301 agaaaagaat tcggtgctgg aagagttaaa gtccaagcaa cttttgacaa tgtgccgtat
      361 gaaggcagta tcgtgaatat gggcgtgaaa aatccagatg gttcagtctg ctacatcctt
      421 ggactacgaa aagatattcg taaaaacatc ggaaaagaaa tcggtgatat tgtagcagtt
      481 acagtgaagc aaaaataaaa gaggttgtga caaaagacgt gtcacaacct cttgataaac
      541 ggtgttcaaa agccagtttc tcggtagtaa gtcaaattta tgcaaaaatg tggaaaccca
      601 tgtttacaaa atttttctta ctactcgaaa cgaagcggct ttatcacaac ctcttgataa
      661 acggcgttca atcagctgtc cctcggtatt agctcaaaaa cggcaaaata tgagaagcta
      721 tttttccatt tttttctctc atactcaggt cataacgctg atttcacaac ctcttctttc
      781 ataatggttt ttcaccatct ttataataaa ctggttcttt gatatggaaa tctatttttt
      841 ccaaccaatc taaaatcttg taacctaact cttctgacat cggaaaagag gcgttgattt
      901 gtgcattgga gatatggtca acatggatac cggaagtgat cgtacaactt cccggaacgg
      961 cagttttgat gatcacagct attttttcgg ctaagacatc gtctttatgg aaccgaccat
     1021 cgtggctagg gaaacgtaca gtttgcatct ctgtatcacg agaaaatgta gtgactgttc
     1081 cgatatgtgg tgtatctccg cctgttaaag tgatcaataa gtctttaccg attactttaa
     1141 cagcagcttg gatcgtgaaa cctagtttgg ttacttcaac tatcgtttct ttttccatat
     1201 taatcaccct gccaacgttt tgaatgctca tttacaattt caaattgatc caaaagtttc
     1261 attgtatggt gattaacaag atcttggatc gtttgaggct gattataaaa agcaggaatt
     1321 ggtggtatga tttgcacacc tagtcgtgct aatttagtca agttttccaa gtgaatggca
     1381 tttaatggcg tttcacgagg aacaatgact aactttcgtt gctccttcat tgttacatca
     1441 gcagcacgtg caatcaggtt gtcgcctaaa ccaacagaga tacctgcgac tgttttcata
     1501 cttgccggta cgatgatcat tccatcggtc aaaaatgatc cgctggcgac agcagcacct
     1561 aaatctttgt ttgaataatg gtaatcaaac aggctttcga attcagttag tgataagtcg
     1621 gattccagct ttaagttctg ttttgcccat ggactgatga ttccgtgtgt ttctatcatc
     1681 ggatattctt ttagtttctt cactaggttg atggcataaa tggtgcctga agcgccactt
     1741 acaccaatca cgattttttt cttccgttgt gccaattgtt ccattttccg cactcctttt
     1801 tatgatgtca aaacagttgc agatcattca ttatttcaaa tatttttccc aatcttctac
     1861 ttcttggaat tttgcacgta caaaatgttc tttcatatcg aaaggaactg taccgtcaaa
     1921 gatagttttt gcacttatcc cacggaaacg aatagagcca ggattatatt ctggtaattc
     1981 tgatgggtcc aatggatggt tcctcattcc tgggatcacg atgatatctt tatctccttg
     2041 gaaacgagtg ttgaaagtcc aaactacatc gttcatgtcg aaaatatcaa catcttcatc
     2101 gactaaaatg actgtcttca attctttgaa ggctgataaa gcaagaatag ctgcttgacg
     2161 ctgaatacct tcatccgctt cgttttcttt acggatttgc atgatggtca tcaatttacc
     2221 accacctgca ggaggattgt agacatttac tacttttcct ggaatagctt tatcgaccaa
     2281 ggcaagaata cttgcttctg taggaatacc ggccatagat acgtgttctt cactgggacc
     2341 aatcgttgtt tgcatgattg gattgtcttt tcggtgagta actgctttga ctttcactac
     2401 ttgtacagct ggattagcat ccccagtata gccaggaaat tctggcattg cttttcctga
     2461 gttcgtgttg atatcttctt gcattgtttc atttggcatg atttctgctt caatgatgaa
     2521 ttcagcacga gcaataccca cttcatcgac tgctatacca tcaacgattt gaataggttc
     2581 gttacgcaaa gctcctgcac accatagttc attgtagcca agtggagtgg taggtggttc
     2641 gaaagtcgtg ccaatggcaa ttgctggatc taaaccaata ttgatagtga taggcattgg
     2701 tttattcaag gcttcgaatt gtttttggaa gtgaccaatg tggcgtccgc caggcatgat
     2761 gtacataccg atcgtatctt tatcttctag aaccatacga tggatcgtta catcgctcat
     2821 tgttttttct ggatctgatc ctaagactac acccattgtg atgtatggac cagcatcttc
     2881 aggagtattt gtaggtgcag gcaaaatgtt gcgaatatcg aagtctgcat cggtagctag
     2941 atgaacgact tcttgtgctg gagcgtctgc tttgtctact ttcacaggtt tgattggatt
     3001 ttctacagcg tctttcaaga aacgaccaag tgttcgataa tcatggtgca aaatttcacc
     3061 tacacgttta cgactagcca ttgttccgat gttcacacgt gtgccgggga aacctttgat
     3121 attgttgaaa gtcatagctg gtccttcttg agtcggacgt tttactgtac cgccagcacc
     3181 gatataacgg taaacaccag ataattctgc ttcaggatcg atttcaatat ctgtttcgtg
     3241 atattgacct ggaagtgttt ttagttcttc gatgactttt cttaaatcat acggttgatc
     3301 tgtcatgaga gattcctcct tagttgtctt tacctatcta tagtaaaagg tgaaaaagag
     3361 gaaaacaatt caacttgttc ggtaaagtat tctacaatgg aatggatgcg tttttttgat
     3421 aatagaataa actatgatat acttatcact aaaagaaagc gcatacttag tgttggagga
     3481 aggaaagtga aaaaaatgga ggagtcattt cctaaagcag taaaagtgga aaatatagcg
     3541 aatattttga aagttacatt tgaaaacgga gaagtaaaat acgtgaaatc tcattggaca
     3601 gaagagataa ccgatgcctt gcaatttgga aaaaaaggaa gaggaaaaag aaaaaatctt
     3661 ctcgcacttt ctcgtaatat gtggattggg actgaagtaa cgattgaagc agatggaaca
     3721 gtattcataa atggaaaaga caggtatacg ccagaagagt tgtggtacaa aggaaagaaa
     3781 agtataccag aattataaaa aataattaaa aaaaacagcg cgaaacaagg aacatattac
     3841 ttcctcgttt cttgctgttt tctactattt cagcgctctt atgactcaaa tctaaatgtg
     3901 gttgtcacaa ccttattctg cacgcaaagc gatagcggcg tcttttttcg ctgccattcg
     3961 tgcaggaaga tgaccgccaa gcatcgtcaa tatagtagag acgatcacta gaataatcgc
     4021 atggacagga tttagttgag caacattttt tagatccgtc atgttgtata agatgctatt
     4081 gatagggaac gtagctagcc atgcaataaa cacacctaat atcccagaag aaatacctaa
     4141 aatacacgtt tctgcgtcaa atacgcgagt gatgtctttt ttacgtgcac ctaaagcttt
     4201 tagtacaccg atttcttttg tccgttcaat cacagatgta taagtaatga tactgatcat
     4261 gatcatactt gttactaaag agatccctgc aaaagcaata aggacataag tgatagcatc
     4321 catcaatccg ccagtcagtt cagtcatcgt tccagctaaa tcagtataaa tgattttatc
     4381 ttcatctgat ttgcctttat tgtaatcatc tagataatcc aagatctttt ctttgtcttc
     4441 aaaattgttc ggataaatca tgatacttga aggcaagctg tctccaccta aataactaag
     4501 caatgtttgt ttggcatttt cgtcaacttt ttcagtagtt aagacattta caccactgtc
     4561 tctttgagct ttgacgattt ctgattcttt gttttcgttg acgatttgag tcgttaattg
     4621 atcgctataa gcgattcctg gagataagag attcattgta gaagaagatt tcacgcgtag
     4681 gatccccgag atcttcaatt catcagaagc attctgatac atcgcatcat aatctgtatt
     4741 agggataaaa ttcccagttg gaagttttgt atagtaagta ttgttgttta ctaatttgaa
     4801 tgttgtacca acgatatcat caaaatcaag tttttcgtct tctttcacat caaatccaag
     4861 attcttcaat gcgttgatat tagtattatt attgccgtct acgatcagca cgacatctgt
     4921 tgctgaggct ggataacttc cggcaagtaa agaataattg tcttttaaaa agttttcttt
     4981 gctagtgtca agctgtgtag ggaaacttga cactcccaca cctgtcattg ctgacatcgt
     5041 actagataaa gaaagagatt ccgtatcagg attttgattc gagaagctga caggctgtac
     5101 tttgccattt acatcacgta aaagattgat tcctgtagta cgggtaaatc cgatattatt
     5161 acttaagtta ggatcgatgt ctgttacgta atcgacgtat gtttgatcaa tcttattcgt
     5221 gtgctgtgct ttatcttctt cgctgacttt tgcagtaatc gttttgctgt ctggataatc
     5281 cgctttgctt gcacccaatc cggcatcgtc acgagtctgg ttagtcgtta ccttagaaat
     5341 agtaatcgga aatttcgcca tcgtttcagc ttgcgtgtta tcgatttgtt tttggaatcc
     5401 agaagaaagg gacagaacga tcgcgattcc gatgatccca atactggaag caaaggaggt
     5461 caagaaagta cgtccttttt ttgttcggat attgttgaag gaaagcttta acgctgtcca
     5521 aaaactcatc tttgttctgc gtaagttaaa ttgatcatct tttggtcgtt cgatgtgagg
     5581 atgggaatct gttaagatct taccatcaga aaattcaatg attcgatctg cgtattgatg
     5641 ggccagttca ggattatgtg tgaccatgat cactaatttt tctttcgata actcttggat
     5701 caattccatg atctggatac ttgtttctgt atctaacgct ccggttggtt catcgcacaa
     5761 aaggatatct gggtcattgg ctagtgctcg agcgatggcc actcgctgca tttgtccacc
     5821 agataactga tttggctttt tatgcatatg atttgtcaag ccgactcggt gcaatgcatc
     5881 ttctgcccgt tttcgttttt cgtctttaga aacaccactt aatgtcatcc caagttcaac
     5941 gttttcaata atgcctagat gaccaatcaa gttgtaactt tgaaaaatga aaccgataga
     6001 gttgtttcgg taggcatccc agtcactgtc cttaaagtct ttagtagact ttccgttgat
     6061 taccatatca ccggaatcat aattatctag tccaccaatc acattcagca tagtcgtttt
     6121 accagaacca ctaggaccta aaatcgctac gaattctttt tgtctgaaag cgacagacac
     6181 accatccaat gctttggtgg tggtttcgcc gactttataa tattttttta tatcttttaa
     6241 ttgaagcata atcacccttc tcccgtattg aaatattcgg tatactaata agtatatcag
     6301 aacaatgatc gtagtatacg aaataaatgt taactgaaga tgaactacaa gaaaaaatct
     6361 agaaattttt caaaaaacag agggagatca atgaatcgta ttttagtagt agaagatgat
     6421 ccgcaattac agttgcttta ccgttctgtg ttggaacgag tgggcttttc agtcatcacc
     6481 gcattgaatg gagaggatgc gctgaaaaaa ctagaagcga cacgtataga attaatcatt
     6541 acagatatca tgatgccgaa aatggatggc tatgacttgc tagactcatt acgtagcacc
     6601 agatttgaca cacctgttct aatgattacg gcaaaggccg attttgagga taagaaacgc
     6661 gggttcaaat taggagcaga tgattatatg acaaaaccca tcgatgtcaa tgagatgatc
     6721 ctacgtgtgg aagcattgct tcgacgttca aagatcaatt acagcagtag cttgataatc
     6781 ggacaaacaa aattagagct agatgcttat acagtgttac aagatcagca ttcgttgatt
     6841 ctgcctcaaa aagaatttct gcttctgtat aaattactgt cttatcccaa caagatcttc
     6901 actcgccaac agttgatgga tgatatttgg ggattagata cgaatacaga agaacgaacg
     6961 atcgatgtac atatcaaacg tttaaggacc cgttttgaaa agacggaaga ttttcaaatc
     7021 atcacagtac ggggactagg ctataaggcg gttatttaaa gatgaaaaaa aagctatttt
     7081 cacaattatg gatctatttt gctagtattg tcttcatttc gatcttagtg acactgctgt
     7141 gttttctcgg ttttattttc ttattgtctc gacattctat ctcgcctgct gaatcggctg
     7201 gaaaaccaac gttatacccg ttattcgtct ttgcggggtt cagtatggtc gtgggtacag
     7261 gaatatcgat ttttgttggg cggcgtatcc tgcatccaat cagtgcgcta gggacaaata
     7321 tgagtctggt agcaacggga gatttttcga ttcgaatgga tgaacagcag aaagtagcag
     7381 aagtacagca actgtataaa gatttcaacg ttatggtcca agaactcaat agtatcgaga
     7441 cactgaggaa tgactttgtg tccagtgtat cccatgaatt caaaacacca ctagcaacaa
     7501 tccaaggata tgttcaattg ttacaagccc caaatctctc tgacgaagaa cgccaaatat
     7561 ttttatatcg gattatcgaa agtatcacgc agctttcaca attaacagag aacatcttaa
     7621 aattgaacaa actggaaaac cagcgtatcc aactggaaaa gaaagagtat cgattagatg
     7681 aacaaatcag agaagtaatc gttttttttc agcctaaatg ggagaaagaa cagctagaat
     7741 tggatatcga acttgctgca gtaaattaca caggcaatga agagtttttg taccaagtgt
     7801 ggctgaatat catggataac gccataaagt acaatcaaat caatggacag attcatatca
     7861 aactatttga gacagccaca gagattgtac tggaagtgac cgattcaggt gtaggaatga
     7921 atgaagagac cagagatcga atgtttgaaa aattttatca aggagataca agtcgtcaaa
     7981 tttctgggaa tgggctagga ctttcactgg ttaaaaaaat tctagaactg catgatggac
     8041 gtattgatta tagcagtatc gaaggagtag gaacgacagc aatgatacgg ttaagtaaac
     8101 aataggaaaa agaataaaac ccctaaaaat tctattgaag gtttttaggg gtttttagtc
     8161 gtttttttgt gattagggaa atgttcttac ggttcttttg gcataaaaat cgctgctttc
     8221 ttattgaact acgagaaatg ttagaggtgt cattgaaaca aggacatgat gcaagaaaga
     8281 gagcgaaagt catgcgtcgc tctctttttt tgggtggata gatggacaga aaatgtaggg
     8341 cttagttttc ttcttgattt aaatactccc aaaatgtatc tgaagccaaa gaatgctcac
     8401 cgactttacg agtaaatgca agataactct ctgttgttgg agaaataggg agaatcacag
     8461 tattttcttt taatagattc ttgactgttt tttccataac aatagcaatc cccatgtcat
     8521 ttgcaatcat attgatgatc aagtcgattc ttgctccttt ataagagatt tttggttcaa
     8581 atccagcttc gcgacacaga tctagtacag gttgatacaa gttcgtagtg gggccaagga
     8641 gcaaaaagtt ctcctttttc agttcgctta gatccaattt ctttttacta gctaaaggat
     8701 gatttttagg tagaactgct acaaaatcgt ctgtttcagt aggcaaccac tcaatcgaac
     8761 ttggtggggc ctggaaactt ctagcaaagt ggatcgtgtc actatgttca ttggcgtcat
     8821 tgtaagttaa ttcgacactt tccacttctt tcaactggac tgtaaattca ggatggcgtt
     8881 tcaaaaactc ggtgattttg gaaaaacctt tataattgat cattgtcggt atcgttaaga
     8941 tatttaatga aagattgttg tctttcgtat aggtttcaag cacttcttgc atagcatggt
     9001 attgttctac gacatttttt acatatggga gcaataagct tccagcttcg gtcaattcga
     9061 tttttctatg ggcgcgttcg aataatttga cgtctaattc tgtttctaac gaaagaatct
     9121 gtttagaaat atttccttgg gtggtgaatt gtcgatcagc agttttggtg aaattcattg
     9181 tttcggctaa atcaagaaaa acttcgaatt tatggatatc catcatattc ctcctactta
     9241 ttccaataaa gaatacttta acacaaaaaa tgaattggtg taatcttctc tgtctgttac
     9301 aatctttctt gcagcgaaag caataattac agaaattttt ctgatttttt tcgcttcgta
     9361 gaaaaagaga ggagtttttt gatgccaact ggagttttga tcaatgtagg ttccgttttg
     9421 tttggcggac taattggcgg attagtagga aataaattaa gtgaacattt taaagcacag
     9481 ctgacgatgg tttttggtgt gtgttcgatg gggatgggaa tctattccat tgcgccgatg
     9541 aaaaatatgc cggctgttat ttttgcttta gtgataggaa cagcgattgg tttgattgtt
     9601 catttaggta atgggataaa taagggggct gcgctgatgc aagtacctat ttctaaaatc
     9661 ttccctagtg aaaagcttgg tatgacccac gatgaattta tcagcacatt agtgacggtc
     9721 attgttctat tttgtgcaag tggtacgggg atctatggaa gtttagattc tgggatgaca
     9781 ggagacagta cgattttgat ttctaaatct gtccttgatt ttttcacagc agctattttt
     9841 gcgtgtaatt tagggtatgt cgtttctgtg atagcaattc cccaattcat tattttttat
     9901 attttgttct tattggcaaa atttatttat ccattgacta caccagacat gatcttagat
     9961 tttaaagctt gcggcggatt cttgatggtc gctaccggtt ttagaatgat caacgtgaaa
    10021 atgttcccag tagctgacat gatacctgca atgatcgtta tcatgccact gagctggatg
    10081 tggacaaatt ggattatgcc actgttataa taaaaatcaa agagaagcca ttttttgctg
    10141 actaaaaagg atcaaatctt ttagtcagtt tttttgtatt tgacaaactg attttgaaac
    10201 tatattatat gttgtataat atagattgaa ataaaatatt acacttgaga atagaaggtg
    10261 acgtaatgca catccagatt ccaactgttc ttcttgatgg tactgtgcta gcagcattaa
    10321 gcaaggaaga tatgtatggg tatgccttaa caaaaatcgt acaagaaagt ctctctgtca
    10381 gtgaatctac actatatccg gttttgagaa gattgaaaaa agaaggatat cttgagacct
    10441 atgatgaacc ttttgaaggc agaaaccgtc gatattactc gttgacacca atgggaagtc
    10501 gtcatttaga agaaattatt gatgaatgga ttgtttttcg agattcttta gaccggttat
    10561 tggaggagag cacaaatgaa tgaatatttg aatgaagttg tggatcatct tcaagaaatt
    10621 cctgaagacg atcgttttga tttgatccag tattatgagg aatatttttt agattctgga
    10681 aaaacattag atcagatcat tgatgaatat ggtacaccaa agcagtttgc cttaaaatta
    10741 aaaatcagtt acttttcaga agaagaacaa gcagaaaacg agttagtgaa aaatccaaaa
    10801 agacaaattc gcctgatttg gttaatcatt atcggtttat ttgcttctcc tgtcctcatt
    10861 ccactagcac tggggtttat attggttatt gggggactat tggttgcttt actagcgctc
    10921 atttttagta tctatgtttt atgtatcagt atcttaggtg ttggcctatt catgatcatc
    10981 tcaggaatca gtgtgtttgg acaatcgatt ctgagtggat tattctttat cggtgtcggt
    11041 ctgttcgcca caggaagcgc agtatttatt tcgccactgt tgctgaaagg aacaaaaggg
    11101 cttttttatg tcatgatgaa ctttgttaaa tggatgggac gacgttttat tacaaaaaga
    11161 gatctgcatt cagcgggcgt ttgaaggagg acacataaat tgagattgaa acattttttg
    11221 attaccggta ttggtctgat gcttactggt ggcctcctag caggtgcaac ttatacatta
    11281 ggcgctcaaa agagtctgac ttgggataat ggtcctcggt tgatcgatat ggttactgag
    11341 acaaaaaaaa tcaaggatgc aaacaaaatc gtcatccatg cagaaaatca aacagtttcg
    11401 gtcatacgcg gattggattt tgagataaaa acgacttatg ataagacaga aaagccagaa
    11461 ataaaggaga aaaatggcgt gttgactgtg aatgcagtca aaaaatcaac aggtgcaatc
    11521 attagtttag aagacacaag tgcacaaatc actattgttg tccctgcaga tcatgaatta
    11581 tctgaattga caatcgaagg gaataatagt gcaattgata tcaacgaagt atcaatcaaa
    11641 aaagtgaata ctaagacaca tgatggctgg gtatcgttca atgaatttac aggaggaaca
    11701 ataactgcga aagatgaatt aggctcactt cgattagatg aggccaatgt ggataacttg
    11761 atcgtcacag gtgaaaacag caacttccat ctagaagaca gtttgatcag caaagaagga
    11821 aaagtcatcc taaacggtgg caatttatct ttgcatgaga tggaaaacag tggctatact
    11881 atccaaacgt ctggtgaatc ttatattgaa aaagactacc agccaataac aaatactttg
    11941 ttagaacaag gacagaaaaa gctaaagatc actgctaaag acacatcgat caatattacg
    12001 acggatcaag aggacaatga aacagattga tcctgtactc aactggatat tttaagaaaa
    12061 aacagcaaag atccttccaa tctttgctgt ttttcatcgc ttaacgcaca taactatagt
    12121 aaaataagaa agaaaatatc taaaaagaaa acagggtgaa agagtatatg aaggtagaag
    12181 aaggtcaaag agaaaagtta aaaacagaaa tggaaagatt acatacttat atcactcaac
    12241 taagccaaac cttctatgat ccagacaaag aaaaagtgat ggttaattac ccgaacaatt
    12301 cagaaggtcg ccaattagag caagtgtacc atgaagtttt caaacattta ttgacggtga
    12361 agaaagagct ggattattat tctttaccga ttatcgatac aggaatattg aagtatgatg
    12421 ggaagaagga acgatttatc tttaaatctg ttcgggaaga tttgcctctt tcagcaggga
    12481 tggatctaga ggtcttggta gaagactatt ttacagaaga aaagcactgg gttcgaacaa
    12541 aattggatta tttaccgcag gcagccggag ggacacaggc aagcggttgg tacatcactg
    12601 aagacaaaga gttagaacta gaaggtgtaa tggcgcgtat tcgaaaaaaa aattaaaaaa
    12661 gtaacattag atatttattg aaggataaag gagcgcagga agtagcatga gagaaaaaag
    12721 agcattttat atcaatggtt atgcagggat tgtcggattg gtcgtattag ctttagttgg
    12781 attgtttttc ttctatttag gtatgtggca agcgaaagtt tgggcacttt ttttaagtat
    12841 ttttctttgg ttgatcacgt tattgttgtt aagttcggca actgtagtca gtcctaatca
    12901 agcaaaagta attttgtttt ttggacaata tttaggtacg attcgagaaa atggcttttt
    12961 ccttacgata cctttggcac aaaaaatgac tgtttcgttg aaagttcgga atttcaatag
    13021 ttctgtttta aaagtcaatg atttggatgg aaaccccatc gaaatctcag cagtagtagt
    13081 ctttaaagtc gttgatacag caaaggcatt attcgatgta gcgtattatc aagattttgt
    13141 agaaatccaa agtgagacag ccattcggca tatcgctagc caatacccgt atgatacatt
    13201 caatgagaat gatttgacgc ttcgaggaaa cacgacggca gtgtctgacg agttgcaaaa
    13261 agagctgcaa gagcgtttag cagtagcagg tgtcgaagta atcgaaacac gcttgaacca
    13321 tttagcctat gcaacagaaa tcgctagtgc catgctccaa cgtcaacaag caaaagccat
    13381 tttgtctgct cgacaaacca ttgttgaagg agctgtcaca atcactcaaa tggccttaga
    13441 gcaaatcgaa gatggacaag aaatcaattt caccgatgat cggaaagtcc aattgatcaa
    13501 taatttactt gtctcaatca ttacagacaa aggaacgcaa cctgttatca atacaggcga
    13561 catgaaagac cgtaagtgac atactttttg taagatagga agaaggagtt taggacggat
    13621 tattgtcttg aactcttttt ttagttgttt taaagaaaat gacaaaattg aaagaagaat
    13681 gatagttgat tcgaaggcag aattgttcgc ttttttctat aatcagtata taaagtaaga
    13741 gagaagggga aaaagtgaaa aaacttctga tcggtctact tgttttcatc gttgtggtac
    13801 ttgcaggggt gaaaatcgca gattacgtag ttatgggtgg agaagaatac tatgtacaaa
    13861 ttacgacaga tggtacaaaa acagtttcaa aatcagactc tggacaagaa acagtcaact
    13921 atagatatat cctgcctggc tatacgaaag agggtaagga aaaagaactg gacttcaagg
    13981 gacaattgac tcgaccgctt cgtaaaggag catatttaaa aatcacctgg aacaaaaata
    14041 aaggtgtcac ttcgtatgaa gaagtcgaaa aaaaagacgt gccgaaaaca gcactggaaa
    14101 aactaattaa agggtaggga aagaaatgaa caaaatagtc gaagtacaga atgtaacaaa
    14161 agtatacgga aaaaacaatg agaaaaagac gcaagcatta agcggcatca gcttcgatgt
    14221 agaaaaaggc gaatttattg ggatcatggg cgcttctggt tctggtaagt cgacactttt
    14281 gaatatttta tccacattag ataaaccaac agatgggcat atccgaatca atcaaaaaga
    14341 tgtgaccaca ttaaaaggaa atcaactagc agattttcgt gcgaatgaga ttggctttat
    14401 tttccaagat ttcaatttat tagaaagctt gacagcacaa gaaaatatcg ctgttcctct
    14461 ttctttacaa ggcgtcagac caaaagaaat caagcaacgt gtccaaaaaa ttgcagaacg
    14521 tttatccatc tctcatattt tggaaagcta tccttctgag atttccggtg gacaaaaaca
    14581 acgggtcgcc gccgcacgtg cattgatcac acaaccaacg attctattag gggatgagcc
    14641 tacaggtgcg ctggattcca aaagtgcccg ggatctttta gatacgatgg acgaattgaa
    14701 tacaaaagat catgtatcga ttcttcttgt gacgcatgat ccgttttctg caagttattg
    14761 ccaacgtatt ttattcatca aggatggcgg tatccatcaa gaagtgaaac gtggagatca
    14821 aagccgtgat tccttctatc gagaaatact atctattctt ggaaacttgg aacagtaggg
    14881 ggagattgac tatgctttgg aaattatcac ttactgggat caagagccgt ttaagagact
    14941 acttggtgtt attctcagga ttagttatgg catctgctat tttttacatg tttgaatcaa
    15001 tggcaagcaa cgaagctttt ttgaaaagta atacgatcgt tgcggctaca gttatcattt
    15061 tccgattcgg ttctgtttta ctagggatca tcacattcgt ttatatttta tatgcaaatt
    15121 cctttttgat gacgatgcgg caaaaagact atgcaatgtt tatgatgctg ggagcaaaag
    15181 gcagaaaaat cgcacagatg attttttctg aaacattctt agtagggatc gcagctactt
    15241 tagtgggttc agctgtcggt gtaggattga caagtatcgt ccaccgatta ttagtggatc
    15301 agttagatct caatatttcg cattttacac cttttagtat tcacgggttg ttgatcactg
    15361 ttttgttttt tgctgttttg tttttattag ctgctgttgt caatgctttt tcgattgtca
    15421 aaaaaccgat tttagcattg attcgtgcgg atcagacacc aacaagaatc aagcagcata
    15481 aattcttgtt tttccttgaa gtagtactgg gaattgcttt tctaggctgc ggttactata
    15541 tgatgaaaca cgtggggacc tatcaagtct ttggtatagg ggtagcctta gttacgatcg
    15601 tattaggaac ttatttcatt ttccattctg tgatcatttt ctttttatca ttactaaaga
    15661 aatcagaaca gatttcattg aaaaaattga acaatttcac attgtcacag ttaaactttc
    15721 gtattcgtga atatacacaa atgctctcaa tggtcgctat gctgtttgcc ttggcactgg
    15781 gcgctttgac ggtaggatta ggttttaaaa atgaaattgc agacttgaca gaaaacaatt
    15841 ctggatatga tctagtgatg aataatcctc gggcagaaga tcagcaaaaa atcaaagaac
    15901 tttcaccaac actttctgct tcttatactc aaaaagaaga tgcgggaacg atttactata
    15961 atgcaagtga atttgcggct caaccattga tcatgataaa acatgaagat ggaacaccgc
    16021 cgaagatcac gaaagaaaaa gttcctgcta aaaaaatgaa tgaactgact gtacaagagg
    16081 aacttcgaag ctatgaattg ccggaacagc aagaaaaaga aatcaaggta gtcagtcaat
    16141 cagaatttga tcaactgaac ttgccacaat ccactttaca gctagttcag gtaaaagact
    16201 tccaagcaaa cctgaaacca atcgaaacac ttgttgctca aaataaaatg aacaatccat
    16261 ctttgcaaaa agtagagtac agcaaccaga aatatgaaat gtatgaagtg tataatggtc
    16321 tattctctgg ttttgaattt atgggattct tcctaggttt agctttcttg accatgcttg
    16381 ctagctgttt gatgttcaag atcttgtcag gaagcaagag tgacattgct cgttatgaaa
    16441 tgcttgaaaa gataggaaca cgacgcgggt tgcttaaaca atcgatccgt agagaagtag
    16501 gcgtgttatt cttagcacca ggaatcttag gtgtagtcca tgtcttattc ggattacaaa
    16561 tgtttggtct attcatgcaa aatccataca aagatatttg ggttccgttt acgatattct
    16621 tcgtattgta tttcatctac tatgtactga cgacatggtt atatactgga atcgtattga
    16681 aaaagagatt gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa gcaaaaatag
    16741 ctcctcatat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt tgaacaccgt
    16801 ttgttcggaa aaagaggttg tgacaatatt tttgtcacaa cctttttttc acggtctttt
    16861 attagaatat agtaaatttt ttctcgttac tcacggaata agctgttaag aaaacggttt
    16921 ccatgtatac tggaatcagt gcaaatgaaa gaaaagaggg tgcaaggaac atggaaatca
    16981 atgaacaaaa ttttggcgaa aactatcact tgattacgat cacgaatcaa aatgggacat
    17041 ctttgtctgt cagtgatctt ggggcacggg ttgttcattt tcaaacaata atcgataatg
    17101 aaaaacgaga gttgatctta ggttttgatg aagcaaaaga atatctagaa aaagaccctt
    17161 atatcggtgc ttcaatcgga cgtatggctg gacggattac gaatggcaca ttcaaattag
    17221 atgatgaaac gttcgaagta aaaacagacc cggacactgg tcattgttta catggtggtg
    17281 cacctagctt tgaagccaag cagtggcatt atacagtcat caatggtgaa aacgaagcat
    17341 cggtcatttt ctatcagact agcccagata tggaaaacgg atttcctgga actttagatg
    17401 tagaagtacg gtatacgctg acgaacgatg atacatggcg agtgacggtc caagggatca
    17461 gtgaccgcaa aacagtattc aatcctacaa atcatgtcta tttcaattta accggtgatc
    17521 cagcacagtc aatcgacgaa catatacttt ggttgaatag ccgattattt gctacgctca
    17581 ataaagatac aacgcctaca ggagaagtag tttcagtaag tggcacagca tttgacttcc
    17641 aacgtcctaa aaaattaggt gaggtctttg ccagtgattt tcgccaatca atgatagtgg
    17701 gcggcatcga tcatccattt ttgttgaaaa aacaatctgg tttactaaat gctgcggaat
    17761 tgacaagccc agatgaaaaa gtatcgatcc aagtaaaaac agatgcttca ggaatcgtga
    17821 tttttacagc aaattttgga gaagatggac cggaaatgcg cgggaataaa ttagtaaatc
    17881 atggcggtat cacatttgag actcaagaac tgccaggagc ggagcgactt gaaagttttg
    17941 gagatgtcac tctggaacct aaccaagtac gcgagtttgt aacggaatac aaaataaata
    18001 taaagaaata gaataaatta aaaagggagt gtgacagtgt cacatcccct ttttaattta
    18061 ttctatttct ttaaaggcag atcaagccag aatgatttgt ctaaacttaa caaggttagt
    18121 acaggaacag ttgcagcttt aactgtacga gtagttgttt ctggtatctg tcttgccgta
    18181 aaattgttcc acaaatccca gattgaagcg acacggaaga tggaagaagc gttgttgacg
    18241 cgttttatcg ttgaaaattc taatcctgtg attggcacgc catctgttgt ccatttgatt
    18301 ggcacatcga atcgcttaga catattgagg atttcagcgt ttgcttcttc agttgttgct
    18361 gcttcttttt tcggttcatc atattttgtc aggtcgtacg cttcgatgat cgcgttcaat
    18421 ttttgtgaat attggcgatc tgtagcataa cgtccttcca aatatttggt tgcttctttg
    18481 tagtcttttg tttccgactt ccaagttggt ttgtagaaat caggattgcc agtcagtcca
    18541 tttttgatca agtcggcata gtcttccaaa ctttccttgt aagaaggata tttacggaat
    18601 tgtgcgcgga tttggtagct ttgtccggaa ctatcttgtt caagtgtatt gaaggtcacg
    18661 ctgcttcctt tatatgatcc tttgatacca aaaaggttat gatttggttc gcttgataat
    18721 aagctgtttc cagatccact ttcaaggata gcttgagcca tcatgactga tgcgtagatt
    18781 ccttcttttt gcccgatttc ctgtgcatca tctgcaatct ttttcaagaa ctgatcagtt
    18841 gtttggtttt gactgaaatg gaacgagcca tctaatccat ctaaaataga tgagccgcct
    18901 gtcagcgaac ctgaagcagc aggtaaacct gctaagttta ctcggacagc aaaatcaggc
    18961 gtgaaatctg aaatagaagt tactcgaact ttatctcctg gttgaggcgc atggataaat
    19021 tgtccgttcc caatatagat acctacatgg tgagtaacac cggaagaagg tccccagaag
    19081 acgaggtcgc caggttgggc ctgacttact ggaatctgcg tacctgcata ttgctgttcg
    19141 cctgtccagc caccgatata atgaccggtt gctttcatat atacgtaata agtcaaacca
    19201 gaacagtcaa aagtatttgg accttttgct ccccatacat atggttttcc aagatgcttg
    19261 aatgcttctc gaacgattgc ttgttggaca ttcgttgtat ttgtaggcaa tacagcatca
    19321 attggtgatt ttacaacaaa atcagaagaa gcagaagatg gattctctat accgctttga
    19381 tttgctgtat ttggacgaga tgaagcattg ttcgttccgc cattcgatga accattgttt
    19441 ggatggtttg gttctctctg agtatttcca ttgttattcg atccagatgg gtttgtttga
    19501 ttcgaagaat tcccgctgtt cgaattattg ttattattgt ttgaattatt tgaaccatta
    19561 ttattgttgt tattacccac atctggtttg tttggcgttt ccggatctgg tgtactaggg
    19621 acttcttcac taggatcagt tggtttctct gttgaagtat ccggtccagc tttaaattct
    19681 gcagtaatag ataaattgtt cgtacctact gtaaaggtct ttgcatcata atttacttct
    19741 ttggcaccat taacagcgac tgaagcaatt tgttcacctt cagctggcgt aatagtgtaa
    19801 gttaccttcg tttccgctaa taaaccttct accgttccac tttccgtaat atccaaaggt
    19861 tgctgttcag gggaatccgc tgtcgaagca gtcagttgga tcttaccaat caaagaagga
    19921 gcaattgtaa gggaatatgt ctcggctggc ttttcatttt ctgatggatc agccggatca
    19981 atttcagttg gctcggtcga tcctgttgtt gagttagttg ttccagttgg gtcttctgta
    20041 aaagaatccg ttgtttcact agtagctgag ctggatgtag tcgtatctgt tgtgactgtt
    20101 tgatcagcta tttgattatc tacggcaaat acggtattgg tcgacaaaac agacggagca
    20161 atcagccaag tagcagctag caaacgtatc gtttttttat ttttcataat aaactagtcc
    20221 ttttcctttc attgattttc tgtcttattc agcattcatt agacattttt tggaacagat
    20281 aatcgtgtcg aaaagctttt tcttttcata aatctgtctg tgtattctaa ataaaacaat
    20341 ttgtaaataa gcaacgagca ttcattcgtt tttctttgac gttcatttta ttgcatagac
    20401 cacctttgtt tggggataaa caagtgggga taaaaatggt tatgcatatg taaattatac
    20461 caaagtttgg aaagtatcac aaaaatttat aaaaataatg atcctaaaaa gaaaaagact
    20521 gaaatatgtg ataaacatct catacttcag tctttttcat taactattca taagacatta
    20581 ggtcttcatc aaacccgcta acgagagtag tgatcattgc tacgactaga ctaacagcca
    20641 gtcctgctaa gtaccagaaa aaagtaccgg aaatgaatgc aggcaatgtg gtcagactac
    20701 caaatacaaa agcgatcgct ttcacttggg caaatcccat tacagctcca ccagcagctg
    20761 caccaatgca agcagcaaca aatggttttt tcaatgggat cgcaattccg taaacagttg
    20821 gttcggtcac tcccgcaagt aaaatcgaag caaaagcaga accggagatc gaacgggttt
    20881 ttgaacgttt acttcgcaga aatacaccta aagctgcacc agccattcca aaattggctg
    20941 ctcctgtcaa cggaacgatt cggtcgaacc cataagcaga gatattactg atcatgacag
    21001 ggtttacagc ccattggata ccaaatatta ccaaaatatt ccaaccacca gcgatgattg
    21061 cgccactgat cggtccgtta atatccatca tccaagtaat tgcggcagct aaaccttcgc
    21121 caaggtaaac acccgcaggc ccgaatacca ttaacgtcaa aggaaccgtg ataactaatg
    21181 aaagtaaagg tacaaatact aattgcatat tttcgcgaat atattttttg aggaattttt
    21241 caacaaaaga ataaaagaaa atacctaaaa tcgccggcat gacagtagac gtatactgca
    21301 tcagtactac aggaatcccc agaaaatcag tagctgcttt gccactgtct gaaagtaaag
    21361 aggtcagatt cggttcaatc agtgctgcag caatgacagc cgcaatatat ccattcactt
    21421 taaacgtttt ggcagcagaa aaagcaagaa agattggcag aaaataaaag acggcattcg
    21481 acgcagcaga caaaatatga taagttccgc ttgtttcact aagccagcca atcgtagtcg
    21541 ctaaaacaac cagacctttt aatataccag aaccggcaaa cagcggaatg atcggcgtaa
    21601 agatttccga tatcaaacca aatagttttt cgatcggatt tagcttttct ttcggagctg
    21661 aatgatcgat ttgacgcgtc aattccttgt aagcaggagc caatccctga tccatgatta
    21721 tttctgcata tctatcgagt aaaatgaaat acttaatgga agggatttgc tgttttaatt
    21781 tttctgcatt ggctactggc tgttttttca atttgatacg aagccgagtc gcacatggaa
    21841 ggacagaatc aatattgtct tttcctccca actgttcaat cagcatatga atctgctcgg
    21901 acagtaccat ctgttcagga ttcattgtcg tttccattag aagaccactc cactcactaa
    21961 tataatattg gcgtaaggtg tcatttcgcc tgtacgaata aatgcatgac agttattcaa
    22021 ctcttttttc atttcttcat gtgggataaa gctaatcggt gtatctggta acaataattt
    22081 gattttttcc aatatttccg ggttcattgt ctttatttct tccgccaatt caatcgattg
    22141 tacctcaagt tcttctaaaa cgttttctaa aacagataaa aaacttggaa gaccgtttga
    22201 gacagccaaa tctatttttt cagtaccaaa ggggacaggc atgcctgcat ccccgatact
    22261 taatttatca aagtgcccca tttgtgcgat tactcgtgaa atatctgaat tgattacttt
    22321 tccttttttc atgtttgttt cttcctctca ttgttaattt tagactgctg attgttctaa
    22381 agcttcgcgg taagggatag aaggttgcgc accataagac tgcacagcaa cagaagaggc
    22441 tagatttcca taaaggatcg cttctttcaa gttactaagg tctggctgaa gtgtgctgct
    22501 taatgcgcca ataaatgtat cacctgcggc tgttgtgtca acggcatcca ctttaaaagc
    22561 agggacgata ccgtgttctt tttctgtatg atagaaagcg ccggcactgc ctagtgtaat
    22621 gattactgtt ccaataccta attcatggag tttttcggct gctgcgacca aactgttatg
    22681 atctgtcact ctgattcctg taatgatttc tgtttctgtt tcatttggta taatgatatc
    22741 tgtcttttca agtagttcag taggaatcgt ttcacgagct ggtgcaggat tcaggatcgt
    22801 tgtttttcct gcgtcttttg caatagaaaa agctaggatc gtcgcatcta agctactttc
    22861 aaactgagca ataataaagt cactgtttgt aatcagttgc ttgtttttta ggacttcttg
    22921 ttcatggaaa gcattatttg cccctgcatg gatcaagata ctattttctc ctgctgcgtc
    22981 taccataatc attgcttgtc cggttgtggc gccttggatt tcagctatcc cagatgtatc
    23041 gatgttttct tttgtcagta gatctaataa ctgttgtcct tcgctgtcag ccccaacgcc
    23101 tccaataaaa gatgtccgtg cgcctgaacg tttggctgcc actgcttggt tggcaccttt
    23161 acctccgcca gcgtgaaaaa tctcatgcgc atgcatcgtt tcgcctggct tgggcatgtt
    23221 ggttaaacga agggtagtgt ccatattaat acttccaatt actgtaaccg tgttcatttt
    23281 acaaacctcc aactatctca tttattttga tgggaaaatt attttttaaa acgttttagt
    23341 aaaacgtttt aatagttcga taaaaatata gcacaccttg aaagctattt caagggtgca
    23401 gttgaaaatc ttttttctaa tcgtacaggt aatctttttt cttcccattc tttttctggg
    23461 aattggatcc gatctaacaa taacttggca gatgtttgtc ccaattcgaa gattggttgt
    23521 gcgatcgttg tcagtttcgg cttgatatac tcgcacatat ctatattatc atagccaata
    23581 atgctgtagt cttcagggat gctttttcca gcttcctcta atccgcgata taatccaaaa
    23641 gctaattcat catttaaagc aaacacacca gttgcagcag aatcaagaag ttctgctgtg
    23701 atctggtagc caccttgttt tgagaactgt gtaggtaaga ggatcagttg gtcgtgaggg
    23761 atttggtaaa catcaagagc agatttaaac ccctcaatcc gagcgtggac attttccggt
    23821 ggattttcag gatagacaag ggcgatcgtt tgatgtccta gactaagcaa gtgcatgccc
    23881 gctaggtaac caccgcgaaa atcgtctgtt cgtacggcat cactaaatcc ttcagatttt
    23941 ttctgatcca aaacaatgaa gggccggcct tgttttttca aattttcgtt gattgcatct
    24001 gtagagacag cagaagtcgc gataatgaat ccatccacac ctcgacgtgt gagctcggct
    24061 agatattcga tttctttttg atgatcagaa tcagcattac ataatatcgt gacgaaattc
    24121 tgcttataca agatatcctc aattcctcgc atcagtgtac tgaagaatgg attcgtgata
    24181 tcaggaacga gtacaccaat tgttttcgtt tccttggtaa tcatttgtct agcaaaatag
    24241 tcaggctgat agcctaattc ttctttggca gctaaaactt tctgaacagt tttcggactg
    24301 aatttctccg tatttccatt taatatcaag gagacagttg tgattgaaac gccggaaagt
    24361 ttagcgactt ctttgattgt gatctttttt ttcaccatgt tcatactcct atctaaatcc
    24421 tgtggttatt ttcccatgaa atcaaaaaga agtaaatgaa aatcacgtgt gccagtactt
    24481 atttgctttg ttggatagct tcgattattt gtttcgttga gcgtactcgt gcagttttcg
    24541 gaaatatctt ttttatgaac aattgatggg attctttgtc acgatcactg caagcatctt
    24601 cagcaagcac gatatggtac ccgtgttgaa aggcatctaa tgcagtagca tatacaccgt
    24661 ttgttgtcgc tacaccgctt aaaatgatag tttcgattcc acgccggcga agttgaagat
    24721 caagagaagt accaaaaaaa gcacttggat tgtattttgt gatagtcaac atattatctg
    24781 tatctttcaa agaatccttc aaaagtaaat cagtgaattc tggaggtaca gaagcagtca
    24841 ttccacccat atcagtttgt tgactcaaat aagggaaagt ggagatgtct acgttcacta
    24901 aaactttcaa ggcagcggta cgtttcaatg ttcttactaa caaatcattg tttgtcagaa
    24961 tagatgctgc agtgtgtgga gagagtgtac cgttatttac gatctctttt tgcatgtcga
    25021 tcgcgacaaa agcagttttt gataaatcaa aaatcatatt ttcctttaaa tcattcatga
    25081 tgttccttct ttcaaataac aatgtttttt atgtaagtaa atcataaatc gtttatttgt
    25141 caactaaatt aaaggattcc tttctttagt ctagagaaat tcagtggtaa aataaataag
    25201 tgtgagaaaa cgcattcgat gcatagatat agcgagaaat atcgtgaaaa tggaggaatc
    25261 agagtgaagt atgtcgaagt aaaaaatgaa tacaaacgat acaaaatggg agaaacgacc
    25321 attacagcaa atgacgatat ttctttttca attgaaaaag gcgaattagt gattatactt
    25381 ggtccaagtg gagcaggaaa gtcaacgatt cttaatattt taggtgggat ggatacacct
    25441 gatgaaggtc agatcattat tgatgacaca gatattgcgc aattttcaga taaacagctt
    25501 actgcttacc gacgaacaga tgtagggttc gttttccaat tctacaatct cgttcctaat
    25561 ctaacagcaa aagaaaatgt ggaattggca acggaagttt ctcctgatgc gcttgatcct
    25621 gtagaggtat tgaggcaagt gggcctagct catcgattga ataactttcc gtcccaatta
    25681 tcaggaggcg aacagcagag ggtttcaatt gctcgtgcac tagctaaaaa tcccaaactt
    25741 cttttatgtg atgaaccgac aggcgcgctg gattttgaaa cgggcaagca agtattgaaa
    25801 ttattgcaaa acgctagcag acaacacggc aataccgttt tgatcattac acataattct
    25861 gctttagcgc ccatcgctga tagagtcatt cacattaatg atgctaaagt aaggtctgtt
    25921 gaattaaatg atcatccttc atccattgat gagattgtat ggtaggggga ttttatgaaa
    25981 acaagaacat atcttaaagc aggttttcgc gaaattcggc aatctaaagg acgattcatt
    26041 gcaatcatcc ttattgtcat gctaggaaca cttttatttg taggtgtcaa aactgctgga
    26101 cctgtcatgc aaaaaacgat ggatcactat gttggtacag caggactttc tgatttgcaa
    26161 atcgtttcta ctggtggctt gacacaaaaa gatattgctc aagcagaaaa gatcccagat
    26221 gcaaaagtag aaacaggaaa acagatctat tattccaata ctggcaaaaa cgaagtgatt
    26281 caaatatttt cttataacaa aaataacaag cagaacaagc tacaattaac tgatggaaaa
    26341 ctcccggaaa aaccaaacca gcttgtattg gatgaaaaag cggaagatga agggtataaa
    26401 atcggtgata tttatcagat tgattcagat gaattgaaag aaaaagagta taccatcacg
    26461 ggctttgtcc gttctccatt gttcatcaac aatttggaga gaggatacgc gaacgtcgga
    26521 aatggtagcg tcgattattt tgtctattta cctgaatccg tttttaaaac agatatttat
    26581 tctgtcttat atcttgattt tacaaacgta aagaatttga atacgtacag caaagcttac
    26641 aaagataaaa tggagcaaaa tcaagaaaag gcagaaaagt atttacaaga tcgacccgaa
    26701 gaacgcttag aagagctgaa aaaatcggcc aacgaagaat tagaaccggc acagcaaaaa
    26761 atagcggatg gcaaagcaca aacaacgcaa gcaagaacac ggttagaaga tgctaaaaaa
    26821 cagttagcgc aacagtcagc aactatccag cagcttcctg aagcgcaacg aacaatcgct
    26881 gttcaaacat tatctcaaca agaagctcaa cttgctgaac aagaaaggca attagttgag
    26941 aaagaacgtg aactggcctc tgcagaggaa gaattgaatc gaaatgcaga aaaaattgaa
    27001 aatttaacta aaccatcata cctatacaat gaacgttcag aaaatgtcgg ttttcaagaa
    27061 tttggtgatc tgtctgatcg tatcgctgcg attgccaatg tttttcctgt tttctttttc
    27121 tttattgccg cattgatcac ctttacgaca atgacacgta tggtagaaga aaaccgcagg
    27181 gaaatcggga cattaaaggc gttaggttat acgaaagttg aaatcgcaaa aaaatatgca
    27241 atctatgcaa gtctagcctc agggataggt attgttttag gaacgatatt aggaacgaat
    27301 cttttgccaa ggatcatttt tgagctgtct aacgagcggt atgatattgg gagtgcgctt
    27361 attttttatg actggccgcc gattttacaa gcagctgccg cattcttcat tgccgcattt
    27421 ggcgctgcaa tgatcgtttt attcaaagat ttaagagaac ggcctgctgc attgcttcaa
    27481 ccgaaagcac cgaagccagg gaaacgcatt tttcttgaat acatcactcc gctgtggtca
    27541 cgccttagct ttaatcaaaa aatcagttac cgaaatctct tccgatataa gtcaagaatg
    27601 cttatggcga ttatcggaat tgctggatgt gccgggctga tggttgcagg cgtgggattg
    27661 aaagattctc taagttctgt ttcagccaaa caatttggac cgatcattga ctatcaagca
    27721 atcgttacat tggattcatc cacggaagat agtcgtcaaa aagcagcgga tatgctgcag
    27781 aagcaagaaa aagtaaatga gatcctagct attcatactc aaaccgtaga attgagaaaa
    27841 aaaggacatg cttcgcaaag tctgacagtg atcgtaccaa gtaaaacagc tgatttggat
    27901 cgttttatcc atttaactga tcttgaagag aacccacgct ccttgcctaa aacaggaatc
    27961 gctattacgc aaaaagtagc agaactattt gacttatcta caggagatca tatttcgctt
    28021 tatgatgaag atcaaaaaga atggaaagtc gaagtaaaag aaatcgtgaa aaactatcta
    28081 ggtagcttta tttatatgtc ccctgaatat tatgcttcag ttactgatca atcgatgatg
    28141 gataatgcat ttttgctgcg tacagataag atgacaacaa aagaagaaga aatgctttcc
    28201 gagaaactgc ttgccacaga cgctgtgaca aatacgtctt tcatgtccaa acaaatcgaa
    28261 acgcaagaag aatcaatggc gaacttagac tcggttgtct taatctttgt cgtattatca
    28321 ggactgctgg cttttatcgt cttgtataat ctaactaata tcaatatttc cgagcgtgta
    28381 cgcgaattat ctacaataaa agtccttgga ttttttgata aagaagtcac gatgtacatt
    28441 gttcgagaaa atatcatctt tactctttta ggaatcatcg gaggatttgg tgtaggatat
    28501 atattgactg acttcatctt gcaacaagcg tctatggaga atgtcatctt tccattagtg
    28561 atcacatggt gggcttatgt cttatcagca ggattaacta tcgtatttac ggttattgtg
    28621 atgattgtta cccatttcaa attaaagcat atcgatatga ttgatgcgtt gaaatcgaat
    28681 gaataaaaac agaggttgtg aaatcagcgg tttgacctga gtattagaga aacaaacggc
    28741 aaaatagttt ttcatatttt gccgtttttt gagctaatac cgaaggacag ctgattgaac
    28801 accatgaatc agaggttgta aaaaagccgt cctgcatcga gcaaaaagaa tactcaaata
    28861 aaattagctc ctcatgtttt acatttgaga agactgattg ccgtagataa aagcttttga
    28921 acaccattta tagaagaaac aagaatattt tgctatttta aacaagagga tagacaaata
    28981 catgtctgat ctcttgtttt ttattgggca acagacctct tagaatgtat aaagataaat
    29041 tttacaaacg ctttcggttc agttataata ataaatgata acttgtatat ataagttgtg
    29101 gtaggtaata aatcagttga atggaggtaa atatccatga catttaaaga caaagtcatt
    29161 taccaaatct atcccaaatc ttacaaagac agtaatggtg atggaattgg agatttaaaa
    29221 ggaatcaaag aaaaactccc gtatctgaat gatctaggca tcgacatgat ttggctaaac
    29281 cctatttatc caagccctca aaaagacaac ggttatgata tctctgatta cacagccatc
    29341 gatcctatct ttggtacgat ggaggaattc gaacagctaa tagccgaagc aaagaaatac
    29401 cggatagaaa tcatgctcga tatggtgctg aatcacgttt cgacagaaca tgaatggttc
    29461 aaaaaagcac tagcagggga ccagcattat caggacttct tcattttaag agaagagcca
    29521 acggattggg tatcaaaatt tggtggaagt gcttggtcgc catttggaga tacggggaaa
    29581 tattatttgc acttatatga tcggacacaa gctgacttga actggcggaa ccaagcagta
    29641 agagaggaac tattcaaagt tgttcgtttt tggatggaaa aaggggtaaa aggattccgt
    29701 ttcgatgtta tcaatgttat cggtaaagac gaacaattga aaaataataa agaaaatgat
    29761 ggcaaacctg aatatacgga caaaccaatc acccatacgt atctaaaaga attgaaccaa
    29821 gcaacgtttg ggacggattc cactatcatc acagtcggtg aaatgagctc tacgacgatc
    29881 gaaaattgta tcttgtatac agaacctagt agagaagaat tatcaatggt ctttaatttc
    29941 catcatttga aagtcgatta tgaaaatggg aataaatggt ctactcctcc atttgatttt
    30001 gcagaattaa agcgactatt tcatacatgg ggagaaaaga tgagtgaggg taacggctgg
    30061 aatgctctat tttttaataa tcatgatcag ccacgtgcgc tcaatcgatt tgtagctatc
    30121 gatcagtatc gaaaacaagg agcagagatg ctagcaacca tgatccattt gaaccgtggg
    30181 acgccctata tttatatggg agaagaaatc ggcatgatcg acccagacta ttcatcgatt
    30241 tccgactata ttgacgtaga aagtttgaat gcttataagt tactccttga acaaggattc
    30301 acagaaaaag aagcgtttcg tcggatcaaa gcaaaatctc gcgataactc tcgaacaccc
    30361 atgcaatggt cagacacaga acaagcagga tttactacag ggaaaccttg gttaaaagtt
    30421 ggaggcaagc tagaagagat taatgtagaa aaagaactat cttctgaaga ttctattttg
    30481 tcctattaca agaaattgat tcggctgaga aaaacatatc caatcgttgc acaaggagat
    30541 tatcatgctt atgaagcaaa tcatccggaa gtttatggct ttcttcgcca atttgaagga
    30601 cagcagctgc ttgtattaac aaatttctat gataaagata caaggatcgc catcccagaa
    30661 ggattcacag aagccaatat tcttatcgat aattattccg atactgttct tcatcaaagt
    30721 ctggagctaa aaccatacca ggcaattgct ttgctgaaaa attaaaacaa aaacacaaaa
    30781 cgtcgttcct acgagctatt ctcgtaagat cgacgttttg tgttttattt aaaataatct
    30841 tcttcagaaa atgaagagtt ttcatactct cctttatcgc cataaaattt attgtagcgt
    30901 tgtttgaatt tacggaaaat aaaagtaacg agtaatttga ctaacgtata gataggaata
    30961 ccaaaaataa cgcccacaat tcccattaga tcacccatga caagtaaaac gattaagatc
    31021 gtaatcggat ggatctgtaa acgatcaccc attactcgag gaatcaccaa gtcaccgtgg
    31081 agaagttgta cggcaaacca gacaatgaca aatttgacag ccataaaagt agagtcttgg
    31141 aatgcaatga tcaaacctgg aaagaaggcg ataaacggcc caatatatgg aatgatacat
    31201 aacaacccag cagaaatagc taaaacacta gcaaattcta atccgatcag taagaaacaa
    31261 acccagtaga ctgctccaag gataaatgaa gcaatgattt gcccctttag aaatgaaccc
    31321 aattgttgat tagcaatctt tgtcaaattt ttaaaatctg tacgaaatgc tggtgggaca
    31381 atcgctaaaa ctgactgata aaatttttga ggatctctca aaaggaaaaa agcgacaatt
    31441 ggaccagtaa ataaagtaat aaaaatagct gtaacagttg aaaaaatgtt gctgatccgt
    31501 tgtgcgccac tttcccaata atttccaata aatccagcta tatcagacgt cacgtcgtca
    31561 atagaagcga aaaattgatt aaatgaatcg gcaaaaggtg ttttctccaa aaattgtcgg
    31621 agactctctt gaaaatcttg aaacaaatct ggcaaactac tgatcaatgt ctttgcctgt
    31681 tcttcaagaa aaggaataag ccatatgctt ccaagcccca ataaaaataa aataatcaca
    31741 taaacgataa tgactgacaa gttcctcgaa aggtgcttgc tcaaacgttt gatgactggt
    31801 tccaaaagat aatacaagat cagtgcaaac aataatgggg gcaagatagt agcgataatg
    31861 attccgacag gcttgaatat aaacgagatc tgatggaaaa aataaatgat cagcgcaagt
    31921 aagataacta ttcctaaaac atagtaagag gtttttcctc ctaaaaagcg gatcaaacga
    31981 ttcgttgtat ctgtttcttt tttcactctt tttcctcctt tatctataaa ttcattatag
    32041 acaaaagcgg gtataaaagg aaaatgatag aggttgattg caaaaatatc gtcaatcatt
    32101 catataaact ttctcatcaa ttaaaataag aaaacgcttg acagttcttt taaccatatg
    32161 ataaattaaa tcctgttgct aaaacgtaac tattacggtt tgcgaaaagc gaatcggaac
    32221 attcaaatga aagaagatga gaagaggagt gtcataaatg aaacgattga taggtatatt
    32281 ggccatgctg gttttagcag gtatgttaac tgcttgcggg gcaagtggga aagccgagga
    32341 cagtaaagaa aaattgagcg tgatgacgac cttttatccc atgtatgatt ttacaaaagc
    32401 aatcgtcggg gatgaaggag aagtagagtt attgattcca gcagggactg attcccacga
    32461 ttatgaacct tctgctaaag acatggcaaa gatccaagat acagatatct ttgtttataa
    32521 tgatgaaaac atggaaacat gggtccccgc aatccaaaaa acattacaag aaggcaatgt
    32581 ccatacgata aaagcgacag aaggtatgct tttacttccg ggaagtgaag aaggacatga
    32641 tcatgaccat gaacacgggg aagaaggcca tacacatgag ctagacccac atgtatggct
    32701 agctccaagt ttagcaatca agcaggtagc aaacatacgt gatcagctga ttgaagctta
    32761 cccagaaaaa caggaagtat ggacaaaaaa tgcagcagcc tataccgaga aacttcaagc
    32821 actccatcag ctttatcaag aaacctttaa gcaagcaaaa caaagatctt ttgtcacgca
    32881 acatgctgca ttcaactatc tagcgttaga atatggattg aatcaagtat cgattgctgg
    32941 tctttcttct agtgaagaac cgtctgcggc gagaattgct gaactgaaac actttgttaa
    33001 agaacatgga atcaactata tttattttga agaaaacgcc aaagatagta ttgccagaac
    33061 gttagcaaac gaagcaggtg tatctttaga agtattgaat cctttggaag gattgacgaa
    33121 tgaacaaata gaaaatggag aaaactatct ttctatcatg gaagcaaacc tcgaagcgtt
    33181 gaaaaaaacg acagagacag aaaacccgct agaagatact ttgaccccca aaaaagaaaa
    33241 gagcgtctac aacggttatt ttgaagacga ggatgtacaa gatcgctctc tttcagattg
    33301 ggcaggaact tggcaaacag tagatacgta tgtagaagat gggacttttg atcctgtttt
    33361 tgaatataaa gaaaaattga atcaggataa gacagcacaa gaatataaag aatattatac
    33421 gaagggctat caaacagata ttgcttcaat caagatcagt gagaaagaga tggcatttac
    33481 gtttaagaat ggaacaacga aacgttcaaa ttatcgttat gtagggaaag aaatcttgac
    33541 ctacgaggca ggaaaccgtg gcgtaaggta tctattcgaa gcagaagata aggaaagtgg
    33601 cgcttttaga tatattcaat tcagtgatca cacgattgca ccggctgact ccgaacattt
    33661 tcatttatat gcaggaaatg aaagtcaaga agtattgctg aaagaaatgg agaattggcc
    33721 aacattttat ccagatacaa tggatggacg tgaaattgca caggaaatgc ttttgcactg
    33781 ataggcaaaa aagaaccgaa gggtttggat cggctggtca tttagtcggt ccaaactatt
    33841 cggttctttt tatgaaatca atttctttaa tccacggata gaggctggga tggtctcgcc
    33901 gtttgccaac gtgacttctc tggttttttt attaatcgac cgcacatttt gtgtattgat
    33961 aacataggat ttatgacaac ggataaaatt ccgatgcatt ttctcgattt ctttgatctt
    34021 ctcatagaat tgtaattggg catgagtcaa atggacttcc agtttatgtg gcgctcctag
    34081 cgaagtagaa aaatattgga tgtctttgat cggtaaaaat ttgatctcat cattaaactc
    34141 tattttgaag atatcttttt ggatttggga catttgaaaa tcttcgaaaa ttttgctcag
    34201 gatatgctcg acattttctt ttaaatcata aagatcttct ttgacgatat aatcagtcgg
    34261 ttcgatgttg ctttttaaga ttttcatcga catttccgta tgggaagtca catagattat
    34321 ttttcctaaa ggatctaatt cacggatcaa tttaccgatc gctacaccat ccatttcact
    34381 gtcttctagt tcgatatcta aaaagtaaat accaaaagaa gaagttctga tcttggctgc
    34441 attgagaagt tcttccggat cagaggtaga aatatggaca taactgtcta agttttcaat
    34501 catgattcta tttttgatca ccgttgataa aacttctaat tgttttggat cgtcttcaca
    34561 aatataaatg ggaatcatat cattactcct ttattttatt tgtatataaa tcgtttgaga
    34621 aaaacgctgg ttttcaattg atgtttcaag gaaaagataa ggattggtct ttgtcaattc
    34681 atccaagata aacaagccaa ggccttcgtt ttttggattt gtttttgttg agaacccttt
    34741 ttgtttcaac tggtttaacg gtaatgtatt tgttgttgta ttgatcacac gaatcatcac
    34801 ggaatgattc ttcttgagta tggtcaattc gatttttttc ttctttgcag cactagctcc
    34861 ttcaatcgca ttgtccaaga taataccaag catacgtaca aggtttaccg tatgtttcgt
    34921 atccagttcg attggctcag gaaaatgaag ctggacgatc aacccttttt cctgtgccat
    34981 catgagtttt aatgacagta aactacggat ctcaggaact ttcatattat ccaacatact
    35041 tagattggcc ggaaaaaggt tcatcatctg gcgtgtaggt aatatcgttt gatcataata
    35101 agaccgtaat ccttctaagt cgccttctga aatatagctg tgaagagaaa aaagcagatt
    35161 ttggtaatca tgtttgaatt ctctcaagtc ttgatagttt ttttctagat ctttgatata
    35221 atcctgttgc atcctgactt gttgctctaa taactgatca gctaatttct tattagagat
    35281 tttccaataa taaaccaaga tgatcaggcc aacacacaga tatagaatga aaaaactcgt
    35341 attcaaagct aagacatcag gtgtttcacc agaaaaacgg gtataaaaaa taatgatata
    35401 gtatgtaaat aatatcaatg tcccgatcgt accgatcata cggcggtcca cagtgtgaaa
    35461 ccaagtctct aacgattttt ttaaacaaaa agctaataaa gcagataaaa aagcggataa
    35521 gacaatgtga aaatactgca atgaatctcc tggttcaata accgaagatt tcaaaacaaa
    35581 aaaatcgccg atgcttgtta agtgatctcc taaaagcgac gtcaataacc caaaaggaag
    35641 cgcgtaaacc aattgttgac gcgaagtcga aaagaagaaa aaagtaagca tcagcattcc
    35701 tatagcaatt agagcagtaa aaatccctaa aatcgaatag acccatccaa tcaaaataca
    35761 agaaatcaga atgactcccg caaacagata tttgtatcgg atgtgatggt caatcaataa
    35821 gatacaaatt gtgtaaatca aatattgcaa cgctatggac cataaaaaca taaagtacag
    35881 ctcccattga tttttaccaa attatagcac aattggcgta ttattttttt aatttttcag
    35941 ggattttgaa ttcagaactc ataccaaagc agcagccaga tacaaaaaag tcagataagt
    36001 tagttaattg tttaatgatt gtttttttca tgaaagattc ctccaaaatt catcaagtag
    36061 tttgtaatag gaagcaacgt agctatttct aaaacaatcc caagtagcaa ataggtagaa
    36121 aagtaagaag ctgagaaaaa taacgtaatg agagaaaaaa ttagaaacat gctgatcgcc
    36181 ttctttaata atgggggacg tttctcgggt tcaatgggat tgattgctgt acctcttgat
    36241 ccatagcgaa gcagtaacaa aaagcagctg attaacaaaa agaccatcat tgggaaggag
    36301 atagtcaatt gcagatgttt catcaccaag ggaacgcccc ataaataaag tagtgtccac
    36361 agcagacaaa cgaattcaga gtcggaatgc aatccataag catatctgcg gatgcagata
    36421 taagaaagaa aggtgattcc tgtttccgcc catgagcctg tcaccagaga aaagactaga
    36481 acgaccgcta gttttccaag attattcaat aaaacttcta agacaaattt tacttggaca
    36541 tacaccatat cttcttccga tttgtctccg ctgaataagg cttctaataa tttgttcaca
    36601 actttatctt tcatctcata cgtacctcca ccacaaattt tatgctaaaa aaaataaaaa
    36661 acgtcttttg tttcataaaa agtggttttg acatcaaaac cgtcatgatc tcctaaaaaa
    36721 atcttcgttt tccaagaacc ttaccaaaaa aagtgacagt tttgatacga aaagtacttt
    36781 ttatgacaag tttgtgcttt ttcgagtgat ttatgttaaa aaattactga ccttataaaa
    36841 ggtgatggag ggattcttat ggaaaatgaa caattgtttg aagtcggcga aacatatgca
    36901 tttaaatctg atttatttga atcaccaata aaaggaaaaa tagaaaaaat ctatgaaaat
    36961 agtgtgatga tacgtgtcat gaaatgcgca gtagaagaca atgataccgc tcataatctg
    37021 cactggcagt tagttgtacg caaatcaagt acaatagaag aataaaaaca gataaaatgt
    37081 tgagagcata aagaggttgt gagtctcccg tttagctctg agttacaagg aataatgtta
    37141 aaaaacagct tttcatgttt tatgaatatt gccttgtgac cgaggtgttg gcaggagaat
    37201 actgtttatt tgaaaaaagg gctgcgacaa gacttttgtc acagccttta ttttcatgaa
    37261 taggagttac ttttggctac ttttagagaa gtagctttta aggagcagat aaagtcaagg
    37321 cttttatttc tataaatgaa gtagtaaaat gaagaacaga ttttattaca ggaaggatgc
    37381 cgataattgt gatcattgtt gcaggaacga tcggtgcagg gaaaagcaca ctaactgaaa
    37441 tgcttgccca agatttagaa acaaaacctt tttatgagaa cgtggaagat aatgaagtat
    37501 tgccgctatt ttattctaat ccagaaaagt atactttttt attacagatt ttctttttga
    37561 acaaacgctt tttggcaatc aaagatgctt tcagccatga tgacaacgta ctagaccgct
    37621 ccatctacga agatagtatg ctgtttcatt tgaatgcaga tttagggcgt gtttctgaag
    37681 tagaagtaaa gcagtatgaa ggtcttttag aaacgatgct gaaggagtta gaagaaattt
    37741 cgccacaaaa gaaaccagat ctactggttt atattcgtgt atcctttgaa actatgttag
    37801 cgagaatcaa aaaaagaggc cgggaatatg aacagctaga acaagatcct gaactctatt
    37861 cctactataa agaactcaat cgacgatacg aagagtggta tgaacagttt gatatatgtc
    37921 ccaaaatagt gatcgatggg gacaaatatg atttcgtagc cgatccggca tgtggagaac
    37981 aaatcgtaca agaaatcaag atgcgggcaa agaaaatgac agaagaggca gatgcccagt
    38041 cgatccgcta cactacaaat aacccgaaag caaagggaat ctttacaact aaataatata
    38101 aaaactaagc aaattgctca ctcgcagata tttctctgtg agcagcatct tgcttagttt
    38161 ttttgattca ttgagatcaa atagtgaacc gattcgtatg ataaaattgc cataaatgaa
    38221 atgtctgagt gagggccatg atcaaaaata aaatggaaac gatcaaaatc gaatgggcgc
    38281 caaacagatg atgacagaaa acaaggacaa tagctcctgc gataaaggca agaacgacac
    38341 ttagatagtg gaaaaatcga tcaaaatctg ctttttcttt agaaatacaa taatcatata
    38401 agttcgttgc tacccctttt aaatttccag ttgtaaataa attagtgtag gcacgcccgt
    38461 tgattttatc aaaagctacc cactggatcg atgcagtaaa agcaatcaaa atcgttacta
    38521 atgcgggatg ctcatggacg ggtgtcaaac taacaaagaa aaaaatcact gcttcataat
    38581 atagaacaaa caagcgccag aaatgttttt ctttttttct aaaataatca attagatact
    38641 ttgttagaag aatccctaag aaaaagaaaa gggtagacaa tactttttta ccaacactta
    38701 gccattctcc gtcaaatgct tggatgatcg atagaatgat attgccagtt tgagcagagg
    38761 caaaagcacc atattggata taagtataac tgtccatggc tcctccgata aatgtcagca
    38821 aaagtcctat tgtacgcccc tcgtgaaagg aagtctgcat ttttttcatc accttttatg
    38881 aatatttttg tcttccttat cttagcataa acgattgaaa aaaaggaaaa attttcagaa
    38941 aactaaaatc atatcgcttc ccattttcat ttttagaaag gtctgttagt ataaagaaaa
    39001 aatagacaac gaaactttaa ataaccaact tgaaataaac aaattcaaag aagaaagatg
    39061 ggaaggaaat caatcagttg aatgaaaaag aaattctccg attacaaaaa gaattgaaac
    39121 gctgggagaa caagtataaa aagcttcaac aagtctttcg gctacaagaa gaaatcattg
    39181 ctacctatga agcggcttat ggcgaagcac ccggacttat tgaggaagaa gtacaagtaa
    39241 aagaaagtga aggaaacagc tctttcttta aaatgatgga gaaacgttcc tataatcgct
    39301 tcaatcaaga acaaaaagca gctatcacat atgatatgaa gaaacatctt cgaatcatag
    39361 caggagctgg gagcggcaaa acgcaaacaa tctgtgcaaa agctgtttat ctgatgacgc
    39421 aaaaacaagt agacgaagaa cgcatactaa tgatcacttt tacaaggaac gctgcaaatg
    39481 aactaaaaaa acgagtagat aatttcagcc agagaaaaac cgctgtccat atcggaacat
    39541 tccatagtat cttttttagg atatacaatg aaatttgtcg aaaatttcct gaagtagcaa
    39601 tgcaaggaat acaaggagac ttttcaaagg atactgcaca aaaagtgaat gctgttttgc
    39661 aacagctgat acgtaaatat aatctttata tatttgatca atatggagaa aaaacgattg
    39721 cttctcggtt agactattgg cagaatatga acctttcagt agaagaaatg gttcagttag
    39781 ttaaagaaaa atatgattcc attgataaga atgcacgaca gccgatatca gaacgactgt
    39841 atggattgct cacggaactc caagaacaaa aaagaagcca gcaattgcta gagttcaatg
    39901 atgtactcca aaatctgaaa agcgctttgg agaatgagga gatccagcat tatatcggcc
    39961 aaaaatatga ttatctattc attgatgaat ttcaagatac taatccactt caatgggaaa
    40021 tcgtgaaacg gatgacaaag gaaaacagga tcaagttgat tgttgttgga gatgatgatc
    40081 agagtatcta tggattcaga ggatcagagc cagcatacat caagaacttt gaaaaagaat
    40141 atcctaccaa aactcttttc ttattaacta attatcgttc tcgggcagct attgtccaag
    40201 gagcaaatag attgatcagc tataataaaa atgatcggat accaaaggcg atgattccag
    40261 cacaaaaaga agcaggtgtt atggaagcct atttgttttc tgatactaaa gcagaaagtc
    40321 agtggctaat caaacaaatt cagacattta ttcaaaaaaa tgggaaatat aaggaatcaa
    40381 tcatattata ccgatcagct tcacaaacgc agcagcttgt ccaatctctg ctgaaaacga
    40441 atattccttt tgtactggaa gcagatagtc catatgaagg tatctttggt atcaagtctt
    40501 tccaacattt ctatcaaaaa attgttcatt ggcaaacagc actgaatctg caaaagaaaa
    40561 atcaggccta ccagcaattg ctccggcagc tgatggcaga ctgctacctg aaaaaaagtg
    40621 aatgcgatca atacttttct cctaaatatc aaaatatagc cgttgcagat tatattttgt
    40681 cgataagccc caatttaaaa tcgaaatctg cagaaatccg agagtttgag gaagcgttgc
    40741 gtaaaacaga ccagcatcaa gaaatctatt cgcttgttca aagctatctt catctgccac
    40801 gtatagctaa ggaaatcgac cagagtgatc aagaatggat acgagaagaa gtaaagcagc
    40861 atgctacttt cagaagactc caagccttat cgcaagaaac ccaagcgaca gctaaagaat
    40921 taaaaacccg cttgattgct tacagacaag gaaaacttga tgcactatgt atccagagca
    40981 ttcacaaaag taaaggtctt agttaccgaa atgtcttttt gattggttgt aacgaaggaa
    41041 gtttgcctta taacggagcg acagaaaaga aagtaatcga ctttaatgaa ataaaagcag
    41101 aaccagtaac gacgatagaa gaagaacgaa gactatttta tgttgcgatg actagagcaa
    41161 gaaatcgtct gtatctatgt gtacctcaaa tgaaaaattc aagaaaattg aaagtatcga
    41221 gatttatcaa agaaaccggg agtcgtgtga aaaaaggaaa gtgatagaag agagggtgtg
    41281 acagaagtgg tcagtttcaa gaaagaagaa ggaatgtacg aaaattgctt ctcaaatttt
    41341 tgtgaaattt cagcttattt tcgaagaagc tatttctgga acacagttta ttcggaaaag
    41401 ggaggtgtga caagaatttt gtcacacctc ccttatttat tttgaaaatg agaatactat
    41461 tatcaaaata gagaatatat ag
//
LOCUS       DADLIO010000018        39616 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.018, whole genome shotgun sequence.
ACCESSION   DADLIO010000018 DADLIO010000000
VERSION     DADLIO010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39616
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.018"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(<1..316)
                     /locus_tag="JOX41_001087"
     CDS             complement(<1..316)
                     /locus_tag="JOX41_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAY6448846.1"
                     /translation="MWIETKTDKNGKKVYKYNERYIDPKTRKRKKVSITYKNKSRETQ
                     KVALLELNKKIDIKLNEKTLHKPDLTFHELVEEWLVIYKRQVKESTYYPTNNILNTIK
                     KKI"
     gene            complement(432..998)
                     /locus_tag="JOX41_001088"
     CDS             complement(432..998)
                     /locus_tag="JOX41_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448847.1"
                     /translation="MAKKVMGQDGKMYKVKKPFYKRVWFWLLAVVVVFIAIGSQGGSD
                     DAKNTVAETTKESVTEVSSAESVAESTVVEEETETTETTIEEVTQEESVPREYRNALS
                     KAESYLGWAGMSEQGLREQLEFEEYPSDAIDYALANVDVDYNEQALAKAESYDDWASM
                     SDSQLYDQLIFEGFTNEQAQYALDNLPQ"
     gene            complement(1134..1787)
                     /locus_tag="JOX41_001089"
     CDS             complement(1134..1787)
                     /locus_tag="JOX41_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448848.1"
                     /translation="MKKVSVMLLLSTALLLSACSNNKKAESTDTTSNQETKISKTKET
                     TETSSSTSKSTSKTDSSSTVTSSNQATAEPSPTVISSSQSTIQTAPQEETYEQMKQRT
                     LQSTPADRANWSNKEWEAFGVALYENGLTTDDAGNIISQDQKEQQAASQQNPEDQQTS
                     AQQDADTLSLTDFVNKYGMSPVAWKVQNGMSEEEALRTTQQKTSGEVQLGFSKYGIQ"
     gene            complement(1837..2265)
                     /locus_tag="JOX41_001090"
     CDS             complement(1837..2265)
                     /locus_tag="JOX41_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAY6448849.1"
                     /translation="MEMDTINLVEELKRKYQSANPFYICEKMGIKIQYVPFIENPKGQ
                     FQEIRDRAIIFLNDELRDSEERFYICAHELGHAIFHRGLSSYYVSTRTSRSKSESEAN
                     CFAANLIVSLYKEDNDQYPKKIEELKNLYGLPESAYRFLI"
     gene            complement(2270..2644)
                     /locus_tag="JOX41_001091"
     CDS             complement(2270..2644)
                     /locus_tag="JOX41_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAY6448850.1"
                     /translation="MSLVTKIKELADEKHVTIAEVERQVGISNGQIRRWDKASPKSEN
                     LKKVADYFGVTTDYLLGNNNVPKWATKEEVVELDKLLDSNVNMSYGGETLTPEQIQRV
                     KDILIATFWDIVKEDKEKGKKM"
     gene            2948..3133
                     /locus_tag="JOX41_001092"
     CDS             2948..3133
                     /locus_tag="JOX41_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAY6448851.1"
                     /translation="MSENLDLKIRAEMRKRRMTFKELAALIGISGAYLSDILNGNRDG
                     KKAQQHIETVKKILDIR"
     gene            3146..3394
                     /locus_tag="JOX41_001093"
     CDS             3146..3394
                     /locus_tag="JOX41_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448852.1"
                     /translation="MTKLKKQDFVKKYNYSPSTYQRRMSELKNTAIFSAAYERVTGQE
                     VWINTELYDKFLSFKSYNRLRTRKVTPKEFIEKHLVDL"
     gene            complement(3697..4155)
                     /locus_tag="JOX41_001094"
     CDS             complement(3697..4155)
                     /locus_tag="JOX41_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448853.1"
                     /translation="MIKILSDYQVAITLIISISGFFLSLYNLFKDKRKITLSYFLVKH
                     DRSNRMILTGVIANPSKMPNSIIECTYLYNGKKINCSHYHANGFDMGSIHKSSLLSPI
                     PLAQAISPGYSVAFSEVLDMKDILPGEKLVMVIRTANYQKKFKLKLKDSF"
     gene            4323..4640
                     /locus_tag="JOX41_001095"
     CDS             4323..4640
                     /locus_tag="JOX41_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448854.1"
                     /translation="MLIATDTLDRIFLKDEYKLRNIDASGILVFDLYDNGKIGIYQAS
                     DIEETNLAFEQIDDSVELDLDEAILAFEQIAKLLKEAQKNGNSLPTQRVIYQSPGTGR
                     TIG"
     gene            4573..5052
                     /locus_tag="JOX41_001096"
     CDS             4573..5052
                     /locus_tag="JOX41_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HAY6448855.1"
                     /translation="MATLYQLSESYIKVLELAEQLDEEILRDTLDSINEAIEYKAENL
                     AKIVKEVEGKAELIDSEIKRLQERKTSLLNNAKSIKHYLQEEMEKTGKTKIKGELFNI
                     GIQNNPVSVNVINENLIPKGFFTPVPPKLDKKQLKEELKHGDIPGAELVQTKGLRIR"
     gene            5502..5933
                     /locus_tag="JOX41_001097"
     CDS             5502..5933
                     /locus_tag="JOX41_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448856.1"
                     /translation="MKNKLAKTTAIIGLALGSGVIGYAASNAFQDLDTIKANFNTVLQ
                     YGQTKSQRVSELESQLSNNTRTQEQLKAEIEQIKSDKQKEIEAKQREVEQKQQEIATK
                     QQEADSLRQQLSTVQNDKEQLEQRVSELRQYTDQKVGELGK"
     gene            5930..6256
                     /locus_tag="JOX41_001098"
     CDS             5930..6256
                     /locus_tag="JOX41_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HAY6448857.1"
                     /translation="MKELTIYDPNISWAKHTIKVSFMIWGYKGYVTYKVGGNTKGLSL
                     IAIDSDDLYDANFEDNPVNFRDLDEDWFSMELTNDKGDSTLVEDEFDRLGDYIVGVEI
                     IAHEPE"
     gene            6375..7061
                     /locus_tag="JOX41_001099"
     CDS             6375..7061
                     /locus_tag="JOX41_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012197638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAY6448858.1"
                     /translation="MQIKKATDIEQTKGTYLIYGAPGKGKTSTAKYFPGKTLILDIDR
                     TSKVLRGEKNVDIVYIDNEDTWNDWGNTLADLTTNYVGVYDNVVVDNVSELERCILSS
                     LGAEGKNNGVPSQGDYQYMQFRMVNSLRYMKNLDSNLIWTAWEEIDLWTDSDGSSYNI
                     ALPQINRKIRNNILGLCDVVGRLMVKEDDERGFILQATDSTYAKNQLDNRSGCKQSEL
                     ILDGIVRLPE"
     gene            7036..8385
                     /locus_tag="JOX41_001100"
     CDS             7036..8385
                     /locus_tag="JOX41_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAY6448859.1"
                     /translation="MELYDYQNDLVDRARQAYVDGYKAPCIVSPCGSGKSVMVAEIAK
                     RTTRKGNRVLFLVHRRELIDQIKDTFQKMGVDNQLVNFGMVQTVVRHLKTIKKPQLII
                     TDENHHGLAASYRKIYEYYSDVPRLGFTATPIRLNGSGLGDVNDLLIEGVSAKWLIEN
                     HRLAPYEYYAPKLIDTAELKKASTGDFTKKSMDKAVKNTIYGDVLKHYKTLAEGEQAI
                     AYCHSIDASKHTAEIFNDAGYKATHIDAKTPKDERADIIEAFRNHEIKILCNVDLIGE
                     GFDVPDCSTVIMLRPTQSLSLYIQQSMRGMRYRPDKTSIIIDHVGNVNRFGLPDMDRE
                     WSLDTKKKTKTDSDLSIVQCAFCFGAYERPKGDNICPYCGELQPIEERKSELEIDESA
                     ELMKVGETKITLNFENNKYYNMTEDEAESIEDLYAIARAKGFKPGWAYMAAKRKGWL"
     gene            8376..8849
                     /locus_tag="JOX41_001101"
     CDS             8376..8849
                     /locus_tag="JOX41_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAY6448860.1"
                     /translation="MVVGMGGIFGKKAEDVQGSIINGVTIIGDTGKRDSSGNQIVIAR
                     NKNNEVFESSLSNIKRGVVNGTGEESGYVNLKKANEKYHVEGTYVKALSVGGTKGVNW
                     DKRRNKWKARLYFKGEYVLQKDFNTKEEAIQARLAAEEKYFKPILEKYENKKEND"
     gene            8851..9351
                     /locus_tag="JOX41_001102"
     CDS             8851..9351
                     /locus_tag="JOX41_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010050472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF669 domain-containing protein"
                     /protein_id="HAY6448861.1"
                     /translation="MTGFNLDFSKAQQGNEIKDGTYEVVVNKAVENATKSGAEFIDID
                     LIVRNDVDQPFQNKHIFAKIWKAKATGKYNEGMIMAIAQALQLEDGKSYNGFDELLAD
                     FVLKTASVRVKTEESNGYKNVNVKSWDKTNTRGVMNHQFKNGDEPSFGPERSRATTVR
                     NDNLPF"
     gene            9366..11678
                     /locus_tag="JOX41_001103"
     CDS             9366..11678
                     /locus_tag="JOX41_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HAY6448862.1"
                     /translation="MYEKIPKELKNLKQWCVYKLVWDEKRQKHTKIPYNANNGHKAKS
                     NDESTWSDFQTALAAIDHYGMSGLGFFFKPPYFGIDIDNAEGEVERFKSGDIEENIIY
                     EFIESMRSYAEYSQSGTGIHIIARGELPGGRRRKGDVEMYQNGRFFVMTGNAASKYLE
                     ITEPNPKDIKRLYDRYVGDEKIIQFKEENPLMNTVDLPVEEIIKRAESSSQGARFKVF
                     MNGGWEAFYSSQSEADMAFANDLAFWTGRDFEKMDEIFRASAMIRSKYDQKRGSATYG
                     ESLLNKAIADTNSVYNPKRKSDFKIFIKDQEQPKEEKYYSYDDTGNADRFTDIYGTLV
                     KYSYIDKSWYYYDGKVWLQDNTGEVRKMIDTTVDIMGKEPLTIPEGADDETKEALMKA
                     KEKHVKRSRSNAGKNAMMDELKHRLSVLPEEFDKDKTLFNTQSGYLSLHDGLLHEHEI
                     DKMFTRVSNVEYTESVDCPMWEEFINQIFDNDQELIRYIQKCVGYSLTGSTREQCMFI
                     LYGHGSNGKSVFLEIISELMGNYAMTMQAQTIMVKQSQSSANSDIARLKGARLVTSSE
                     PNEGVRLDEGLVKQLTGGDKVTARHLYGKEFEFEPEFKLWLATNHKPIIRGTDDGIWR
                     RLNLIPFTVQIPDHKKDKNLKFKLQTELQGILKWAIDGCLLWQREGLEKPKSVVAASQ
                     DYRNEMDQIGTFIETCCETGPGLKISGGELYKVYREWASDNGEHTFTNTKFGREISKK
                     YSKEKAGGFMVYKGITLKPRKYDNVRELFK"
     gene            11925..12242
                     /locus_tag="JOX41_001104"
     CDS             11925..12242
                     /locus_tag="JOX41_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HAY6448863.1"
                     /translation="MKSEHQIQDEIRIALSKHGCTIFRSNAGQVTTIEGRQFYGMPKG
                     FPDLCGHRNSDGKAIYIEVKNERGKLREDQKRFAEFLNGQPVLYGVARSVEEALKIVE
                     ESS"
     gene            12239..12400
                     /locus_tag="JOX41_001105"
     CDS             12239..12400
                     /locus_tag="JOX41_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAY6448864.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIHRLEE"
     gene            12397..12702
                     /locus_tag="JOX41_001106"
     CDS             12397..12702
                     /locus_tag="JOX41_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448865.1"
                     /translation="MSVDKKAAMKRIIELTHSENWQEDKEIVAEVQKLGKSMWSEKTK
                     RRTPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRAKRENVDSKGRQFKHWEKK"
     gene            12702..13016
                     /locus_tag="JOX41_001107"
     CDS             12702..13016
                     /locus_tag="JOX41_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448866.1"
                     /translation="MEELITKVEQWAKDKGLDQADSSKQMLKTIEEIGEVAASLARKD
                     EYGLRDGIGDVVVTLIILAMQNDMDLYECLNQAYNEIKGRTGKMVDGVFVKSSDLEDS
                     DE"
     gene            13009..13539
                     /locus_tag="JOX41_001108"
     CDS             13009..13539
                     /locus_tag="JOX41_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HAY6448867.1"
                     /translation="MNKKVLIDKQALIDELMKIPGVGSNSDALETIKRFPSYEPQKPV
                     VPKFVAELLDYYRQSTDVDLLALLITFHDWYYRKTKDGEHEEAIDWLVDHPEIYMRAW
                     LFGYELEKEPLYCVIINGRYLVKVFSNTNVVILVPADEFSQYVTQKFQLTEKQIKAID
                     ERYWPFAVPVDEVVEG"
     gene            13536..13805
                     /locus_tag="JOX41_001109"
     CDS             13536..13805
                     /locus_tag="JOX41_001109"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448868.1"
                     /translation="MSDPYITKLEKLSEDFEKNKNKLTKDKLIELVRLVIRGAITREK
                     AQQNIEIFARSVRDGLEKKVKQNEQQTPQNNKTKKTGTECTKDKV"
     gene            13935..14222
                     /locus_tag="JOX41_001110"
     CDS             13935..14222
                     /locus_tag="JOX41_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448869.1"
                     /translation="MKLKDGFYSSSHGIGGLMLDMPTKNPKTREKPKFKVGDMVRCEA
                     EGFIYPFCGYVEHLYNHSAIIRIENTMECDKWLAKSKENLAVARLVDMEVI"
     gene            14709..15122
                     /locus_tag="JOX41_001111"
     CDS             14709..15122
                     /locus_tag="JOX41_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HAY6448870.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGRIIAYK"
     gene            15903..16133
                     /locus_tag="JOX41_001112"
     CDS             15903..16133
                     /locus_tag="JOX41_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448871.1"
                     /translation="MRNYWYVSLTNEYPRTIDDCSVRVVRSVQIKGKYSIVEMLREAT
                     PNEVDKCKLIYCGHGYWKDEYIQQNIERWIDR"
     gene            16318..16863
                     /locus_tag="JOX41_001113"
     CDS             16318..16863
                     /locus_tag="JOX41_001113"
                     /inference="COORDINATES: protein motif:HMM:NF024252.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAY6448872.1"
                     /translation="MHMHIGEKIYKLRRLNNETMNDLVKQTGVSKSWLSDIESGKKQR
                     VDFNKICAIAKHYKVSLEYFRDDYLDSDEHEDIIPLTGETRVKSVKSLEQSLKYLNNK
                     QEPNLLEIKLKDTDSVPEVWYKGERLDELPKGLVDVSYHWKTDDFTNDDRGANDITIQ
                     YFSSFNDKYPDKKTIGHKRDM"
     gene            16864..17181
                     /locus_tag="JOX41_001114"
     CDS             16864..17181
                     /locus_tag="JOX41_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAY6448873.1"
                     /translation="MKEVRPRDEIDKLYKTKRWRDLRQVVIARDFGMCQECKRRGRNT
                     RGTIIHHIVEAREDLSLFWSVDNLECICVACHNREHPERSGGKKKPKPKSHIVKMYST
                     PER"
     gene            complement(17338..17502)
                     /locus_tag="JOX41_001115"
     CDS             complement(17338..17502)
                     /locus_tag="JOX41_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzC family protein"
                     /protein_id="HAY6448874.1"
                     /translation="MGELYKPGEDNKPKGTYKEVGPRGGNVQGGQEVKIDPGDRLPPT
                     SQKGNKWTKK"
     gene            17604..18125
                     /locus_tag="JOX41_001116"
     CDS             17604..18125
                     /locus_tag="JOX41_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HAY6448875.1"
                     /translation="MPQPAKSAKLQLLNGNPNKKNTEELRKRAAAEDKLKMATDKIKP
                     PLWLDSLGKDTFEFIADELLSVDLISNPDVHTMALYSNWYSQYVSLEKQLRKLQREYK
                     LNYALAKKEAEARGEPFNEPNELIGNPLSRQMDTASRNLRSFGADLGLSPAARAKLAI
                     KMADDGGDDDDDF"
     gene            18097..18552
                     /locus_tag="JOX41_001117"
                     /pseudo
     CDS             18097..18552
                     /locus_tag="JOX41_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010965199.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
     gene            complement(18592..18750)
                     /locus_tag="JOX41_001118"
     CDS             complement(18592..18750)
                     /locus_tag="JOX41_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014967994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix domain-containing protein"
                     /protein_id="HAY6448876.1"
                     /translation="MDKYGLKNRIRISNAIDKDLYEGLKKMSEETMVPMSKLLDKAIE
                     LLLKESQK"
     gene            18843..19604
                     /locus_tag="JOX41_001119"
     CDS             18843..19604
                     /locus_tag="JOX41_001119"
                     /inference="COORDINATES: protein motif:HMM:TIGR01453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAY6448877.1"
                     /translation="MKKYIIYKHLNKINGKIYIGVTNDIGRRWRSGGIEYKPPKNETQ
                     HHRSFWNAIQKYGWENFDHLIIEEDLTMKEAFEKEKFYIELYDSTNKKKGYNIAKGGN
                     GGIIYKVHPKGMLGKKQSKEFSSNHSKWAKNHKNNCMTNGDVVWGVTHEHPKGMLGKH
                     HSKESIMKKKAYSGENAVTSKPIVAIERDGTKREFHSAKLCMAYYSISTCVFYRLLKD
                     GAPYVINPKANYRNKEKILAIEGIMFKHKEDTEVS"
     gene            19791..21143
                     /locus_tag="JOX41_001120"
                     /pseudo
     CDS             19791..21143
                     /locus_tag="JOX41_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329397.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
     gene            21159..22379
                     /locus_tag="JOX41_001121"
     CDS             21159..22379
                     /locus_tag="JOX41_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAY6448878.1"
                     /translation="MSILDRLRSFGRAKPKASKQEYFLNDPGLIPYLVGKDEISEGIF
                     SVISRVSNVFASLPLKMIDVEFGQPDDCPAYNLLSEGPRYFTKFDFFRDVEVLRNYQG
                     NAYVQIFRNINGEVADMALVKPGACHPVIDMDSGELYYQVTATDKGSYKQVIYVHYME
                     MLHFKQPRFGGLEGTDPTKVLTNTLGYDREVRKISLSQLKGSNEGLKVKFASNMDEEA
                     KKATVKNIADFYRQNGGLLVEENGVEIERLQRELVDSKLLDTDKVSRSRIAMVYNVPE
                     HFIGNNQSSYSSQEQLNMEFLTYNLVPTVNQYEAELNKKTLSRTEKAKGYRYKFNVAS
                     LLRADTQARGQFYQIMRRGGAYSANDVRRFEDLQPINKTGMDDYHISGDLYPIDMDPT
                     LRKTTSSKSVAENG"
     gene            22414..23091
                     /locus_tag="JOX41_001122"
     CDS             22414..23091
                     /locus_tag="JOX41_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HAY6448879.1"
                     /translation="MKKVTLSGDVVDNDTAWLYDWFGINCISPGKISAALTEAAGDEV
                     ELDISSNGGDVLAASEIYTAIRAYPGKVSGNVVSIAASAASVIACACEPLRISPTAHI
                     MIHNAWVTTSGNAEELKANAEMLSSVDESIVNAYEIKTGLDRKKLADLMAKDTWLNAQ
                     TAVAEGFADEIMFAEAPVTVLNASQPVIPKNAVTKLKNLILKAEAPQEETLLQKKLKA
                     LNGGKNE"
     gene            23088..24281
                     /locus_tag="JOX41_001123"
     CDS             23088..24281
                     /locus_tag="JOX41_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAY6448880.1"
                     /translation="MNLEQLKNAWVEAGSKVSDLNAQLNAALVDDEKTEEDVVSLQAQ
                     VKAARAKRDGLKEQVANMEAEQVLNVKKEPLDKKDENLKNKFIKDFKAMVNGDPAIMA
                     TLTSNTDESGNAIGLTIPVDVQTTIHTLVRRFDSLQEYVNVEKVTTTSGSRVYEKWSD
                     ITPLTALDTEDGEIPANDDPALYLIKYLIKRYAGISTVTNSLLKDTAENILAWLSKWI
                     AKKVVVTRNTKILAAIDGIKAAQKKDVTDVDGIKDIVNVQLDPAIEATSMFITNQDGF
                     NVLDKVKRADGSYLLQKDVASATGYTFLGKPIKKIASRFLPNKGTQATPKYPLYIGDL
                     KEAVTLYDRENMSLLTTNIGGGAFETDTTKVRVIDRFDVQLVDDEAVVLATFTTIANE
                     TPAKV"
     gene            24296..24622
                     /locus_tag="JOX41_001124"
     CDS             24296..24622
                     /locus_tag="JOX41_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HAY6448881.1"
                     /translation="MILDPKMDLGEIKNALKIDTDDDDVEVSRAAQAAIAYIRGAIGN
                     DKPSFYKQENETVDLINLAILQLADHYYNARSATVSGNLREYDLGFTSLILQLKASYL
                     LFVEEE"
     gene            24626..24961
                     /locus_tag="JOX41_001125"
     CDS             24626..24961
                     /locus_tag="JOX41_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HAY6448882.1"
                     /translation="MPLIQTGNLNQRIKFVRDTTVKDEDGQVVPTSTTILTCWASVQT
                     QRLNDIKTSIGTALEGTLTFIIRYQQKSELTNDMKVRWNGKTFEIITITKGEFAKDFT
                     TIIAKEVSK"
     gene            24958..25353
                     /locus_tag="JOX41_001126"
     CDS             24958..25353
                     /locus_tag="JOX41_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448883.1"
                     /translation="MSVEVDATEVYKALREVKANVQRVESPALRKAGEYAQEELRQNT
                     PYWDGTKSNGKRGSYMQEHAKNHVVTSSIKNGLVEVGYDKDVSWRMHFIEFGTIKQRP
                     KGFVQKTQKQIEKQVTQIIADEVKRRLGL"
     gene            25350..25721
                     /locus_tag="JOX41_001127"
     CDS             25350..25721
                     /locus_tag="JOX41_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448884.1"
                     /translation="MKTAVSQVYSILNSNEKTKNIDFYTNSVPESAQTVPSLPVGRIT
                     EISGNYEDFASNNPLTIQFNVQVDVWVSTMKEVDAFYFALDEVMRGNGWQCAYTEQTD
                     DEDLEGAKRIIKRYVANISLN"
     gene            25737..26297
                     /locus_tag="JOX41_001128"
     CDS             25737..26297
                     /locus_tag="JOX41_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAY6448885.1"
                     /translation="MATVGFESVIFGVKTGAGGTLKELVADKSKGGAIEAKITGLGAT
                     SNTTYASNVPFFIASKGVSSPKVTLDVADLMDNGIYSEIIGAKTVDGANVIGSETEAP
                     YVSVVMVTANKEGKRLFMGLTKGKFSHPDIDMKTAEDKGVELQTDSIEGEFISDERGY
                     VYLTAVESEGMTLQKFKDLVNNKEGE"
     gene            26422..26733
                     /locus_tag="JOX41_001129"
     CDS             26422..26733
                     /locus_tag="JOX41_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448886.1"
                     /translation="MIELQLKLDGKKKTFKQQDISARAMRECIKFYEKAEKADLTDLE
                     AIDSMIAITADIFQDPAVTFDAILDGLTASELVPALESVFEQINELGNNEKKQTASKK
                     K"
     gene            26757..26948
                     /locus_tag="JOX41_001130"
     CDS             26757..26948
                     /locus_tag="JOX41_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448887.1"
                     /translation="MDQIYKDLIEAGWTMRDVDEADYHYLLHLFGEVESGEEYVDGAD
                     FIKQFLSAEDLVKLEEGGK"
     gene            26948..30796
                     /locus_tag="JOX41_001131"
     CDS             26948..30796
                     /locus_tag="JOX41_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HAY6448888.1"
                     /translation="MAGKGQPAGNIKLGISLDSTSFGNTLDEINAKVKQAESNMRANL
                     KAYDSAGRSYEALSQKTKDLSTVMEGQNAKVRELTKRRDEAISKYGEESKQVANLNTQ
                     INNATAKYNAYSRQLNDTKKELVYSKTAVNDLSNEIKENERQMNAEVKALKAAGDESG
                     AFEAKQKGLAKQTELSEKAIEEQRKVVKLMADEFGDSANETEDAKRALEKLERQSQIS
                     SRQLEALKSSSDQSGKEIEDFGDKSTRSARKLDGLKDKLSSLKSAFSFGAVAGLAHNA
                     ISSVVSGVQGLVGEAVNASDSLMKFSKTMEFANFGKSQIESSKKEMKDYADKTVYGLE
                     EILNTTAQLASNGIPNYTELTKAAGNLNAVAGGSSDTFKSVAMMLTQTAGAGKLTTEN
                     WNQLADAIPGASGLLQDAMLKNGAYTGNFRDAMAQGQITSDEFNQAIVQLGMNDGAVK
                     AATSTDTLSGSWEQMKSTVINGLQSIIEKIGVENITGFINRVTKGIENSIPKITQFIG
                     WLRDIGTWIVENREPLTWIVGIIGGITLAVKALNVASMLLAITGGTLAAPFVAIGVAL
                     GALAGALVIAYTKSETFRNIVNAAFTAVKNVVMSVINNLVEYYKMLWSVLQWLWEKIK
                     EWASWIGNKFIEMKNSVVNTVQNLWNGVKNFFSNGVGDTWNKVVGWVKNIFNKATELK
                     NNVSDVIGNLWNGIKDTFRRGIDTVFNWFSELPTKMKNAIIGGKNAIVDAFKSIFNAA
                     LKAIGKPVNAIIHGASWVLEKLGAEPLQEWDVPQYATGTPAGGHPINGPMMVNDGRGA
                     ETVITPDGRAFIPKGRNVVLNAPKGTHVLTAEETAQLQGSKAPKYRYKKGTNFFGNMW
                     DSVKKVAGNVGHTIKNVVGDVWDFISDPGALARKVLGGLDVLGGLTKYPLEVGKGILS
                     KATSALTEKITGLFSSGNLDTSVGTNGVYKYLADVAKSVMKKFPGFVATSGYRPGDPY
                     SHGKRNAIDIALPGVTGGSPRYTEAANYAFDKFASKIGYVITNGKVRDRSGQSGQPAT
                     GAWEPWPDGDHYDHVHLNGVKDPQNTQISGDSVGGSGVERWRNVAIRALKMTGQYSTA
                     NLNALLNQMRTESNGNPNAVNNWDINAKNGTPSKGLLQVIDPTFRQYAMPGFNSNIFD
                     PLSNILASIRYALSRYGSLTNAYRGVGYANGGIVNQHQIAEIAEGNKPEIIIPLDKAK
                     RSRAMQLLSIAMDKLGVSPKTYGNATTVSSDYEILEAIEKQAATTNQLLSLLLAFFKG
                     NSRTDRDLALDIQKILVRRM"
     gene            30797..31669
                     /locus_tag="JOX41_001132"
     CDS             30797..31669
                     /locus_tag="JOX41_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448889.1"
                     /translation="MRTVLLRNRINEEIDLSTEDYFATGLSNMGFEVKKEHVGQWGNF
                     RESSESVEISEFQSSVIISVHGFREKELYNSLVQFLSEGPFELEFAFDGETMVRRCSL
                     KSLSKTEIDPKTSLLTDTLELYFTSNWYSVKREKLIQRPNVVKTRGKVFPYKRSYIYT
                     QNLWEKKGVFKFNNNSVYLTNSKERMSPLKIRVIGKCSNPYWEVIQNSQIIATDGYFI
                     DMTETQTLEVSSLFEDTTAILKDIAGVESSVYQQQDYTKTNFVQAPTGEFSIVFHVGG
                     ADVEIELYEERDLF"
     gene            31666..32715
                     /locus_tag="JOX41_001133"
     CDS             31666..32715
                     /locus_tag="JOX41_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448890.1"
                     /translation="MILAVTLFHRDLMLYNEHLFSNSFEFGVDEINEEASSFTMDKYV
                     PVKTGDFLLAKYIPSGKFAYFGVITSQEDEKISCKSLLSLADSEIPTARVSGDNYEEH
                     IRRLIEYYLLNDPTKQLKDILDVKAESATSHSYQATDTNKHKLSAYILNGFKKYNVKW
                     YFKGIQNRKIYTGIRAVNESIYIKDNSSEFSDWDVFVQAPGAGNENKLLIVDKAMKDI
                     EKPIILSTWYLDEENNLTQDGSKENITKPTVNLVNIYDQTAEDKASYEDVAKSELKGN
                     TYSHEIKVNVVRNAKNLNVETIETGMFATISYKGKIYKSVLTAWRISSDKEFVELTFG
                     NIRSRFMDYFEDNGG"
     gene            32719..33543
                     /locus_tag="JOX41_001134"
     CDS             32719..33543
                     /locus_tag="JOX41_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448891.1"
                     /translation="MVSNVDGYQFENVKVSAENDARLYHVLYNRKNQVIDGYDQSMNL
                     SSSGLTVKVAAGAAIIQGRMVVVRQEESITVPANSSGYIALTVDLTQEVIPGSILPES
                     EEYEWTNNQVKLEFITKVIKGNLNNGDKVYNLPLCSVNSTGSTVSISKISDSYELTLS
                     KGEILWRGTALMHDTQTVQPSKKIWQTVSGFLLVWLPYENGQAIEDRYVTTPFYKERV
                     TFTNVLGEIVSGFDDYHKKWFSKRINYNSNTNIFTGAASNASGDNANMVLRYIVSF"
     gene            33561..35621
                     /locus_tag="JOX41_001135"
     CDS             33561..35621
                     /locus_tag="JOX41_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HAY6448892.1"
                     /translation="MANLEIKLSANKRQPYLRHRVVGRVGDGGLTTINVQLLEEDEIT
                     PFVINLNGTLKFVGEVSNGNYTEGEPEIIDSTNGLISYTFTKSNFSTSHQFKQAYFEY
                     VDPNGKKVTFQNFIIDVLERVDINSEQAKYYISSLEKLQSEMQTTFNQFISDKQVQYD
                     QIYSKYNELVRLINESDKQVNDRIDQTNQQIGDLGKLKKMYSNSIDFGGYDYSGNPNL
                     LSKLSYDLIENQNTSAGTLSKGENSFKYNKISAEVEGGVELYYKRRGIANWLPSNKTL
                     VMTVKLRAGADYSPVDGKLILIRYRYVDSGTGKIVLDLPINSNSITQEWKEFSITGTT
                     PTFSPQAYHPWIQFRAQDGVLGEIEMSYDIKIEEGSTATPYQPNLLDDSYWLGKTPLG
                     ENLITNAKFPIITRSNPISGFDISEELIIGETYTVSLKGTKPATKEFHLYYGEANYQQ
                     LQYQATLLPVEGLTDVWSATFTARNTSETTNLLRVALWQKPNSATYDTVQIDWLKIEK
                     GDTRTPNISQFKYFGEGLKDSNNPNDYSWDVTPEYTEKSLNNTVSLTEPQSIEGLKNF
                     EDGIQSKGKSVLTSDDNKYEVVTLTVTNGNTGSAKLYREGKTVTIYFFALNGKSSGGN
                     DSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSDYTFAI
                     TYTI"
     gene            35784..36230
                     /locus_tag="JOX41_001136"
     CDS             35784..36230
                     /locus_tag="JOX41_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448893.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGVRSDGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYEALEHENGNLKQLNAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            36232..36369
                     /locus_tag="JOX41_001137"
     CDS             36232..36369
                     /locus_tag="JOX41_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HAY6448894.1"
                     /translation="MFSFSDVKMMYDWGCFTDDQVRLFVPLCITDEEADRIISKEESA
                     S"
     gene            36404..36646
                     /locus_tag="JOX41_001138"
     CDS             36404..36646
                     /locus_tag="JOX41_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAY6448895.1"
                     /translation="MKEEALQDVVERLVRIETKLDNYESLREKADSAKDLADKAYSVA
                     LNNAEDIKEMKANNKWSWGYMIGLGITIIGYFLTKL"
     gene            36662..36859
                     /locus_tag="JOX41_001139"
     CDS             36662..36859
                     /locus_tag="JOX41_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAY6448896.1"
                     /translation="MILPDKYYQVIKWTVLTVLPAASVLVATLGKAYGWNGTDMTVLT
                     INAVATFLGVITGVSAYNLKK"
     gene            36870..37886
                     /locus_tag="JOX41_001140"
     CDS             36870..37886
                     /locus_tag="JOX41_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAY6448897.1"
                     /translation="MKKKIILSLSLIMALFLLPINGFAYTINNEFNLGVNEGSSQVAN
                     NQYILLHETANETATGRNEAQYMKRSWYNAYTAYIVGDGGIVYQVGQPGYVQYGAGSY
                     ANANSPVQIELQHTHDKVTFEKNYKAYVELARDSANKYGIPLTLDTPYNQPGIKSHLW
                     VTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANP
                     TLSDGTNHSHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYR
                     PDVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLN
                     IPKR"
     gene            38001..39209
                     /locus_tag="JOX41_001141"
     CDS             38001..39209
                     /locus_tag="JOX41_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448898.1"
                     /translation="MTAEIGIMNKSGIVLASDSASTIGDSKVYNTAKKLFTLDSMHSV
                     GIMIYGNAEFNGIPWEIIITQYKKSIGSSVFNTLEEYADNFIEFVKTASFIRSEQTEQ
                     EQMIGVFQKIISGLFESIEVDINFLISQGTQIDKDVLVKLLQTKMNTNLSQQSQTFIL
                     DIEKALFLSNYGEILKDILNSISTMEGVSEAISEEIQSYVYEIIIRDDVYSSPTGIVI
                     AGYGRMDIFPKLYSYNMFGFVMNILKYSEYESAQIGNDNGSLRSTILPFAQSDVVNTV
                     VQGVDPQITNYLSSQVDSFDDNGKNTYINIIKNISEFQQNQFIFPLLNMIALLPVEET
                     AIIAETLLNLTSFKRKYTTSVETVGGPIDVLAITPNDGPIWIKRKHYFDIDNNIGYRL
                     RKERANDYNN"
BASE COUNT        13724 a         6608 c         8511 g        10773 t
ORIGIN      
        1 gtatcttctt ctttatagtg tttaatatat tattcgtagg ataatatgta gattccttaa
       61 cttgtctttt gtatataact aaccattctt caacaagctc atgaaatgtt agatcaggct
      121 tatgaagtgt tttttcgttt aattttatat caattttttt atttaactct agcaatgcca
      181 ctttctgagt ttctcgagat ttatttttat aagtaatgct cacttttttt ctttttctag
      241 tttttggatc aatatatcgc tcattatatt tatatacttt ttttccgttt ttatcagttt
      301 tagtttcgat ccacattgtt ttcatctcct atttgttgct ataataggaa tagataagta
      361 agccgattat agcaggttta tttttcatca cgtccacaaa ctttggcgag ggaggggcgt
      421 gtttttgtta gttattgtgg taggttatct aaagcgtatt gtgcttgctc atttgtaaaa
      481 ccttcaaata taagttgatc gtacaattgc gaatctgaca ttgatgccca atcatcgtaa
      541 ctttccgctt tagccaaagc ttgttcgttg taatcgacat caacattagc cagcgcataa
      601 tcgattgcat cacttggata ttcttcaaac tctagttgtt cacgcaaacc ttgttcagac
      661 ataccagccc aacctagata gctttcagct ttgctcaatg catttctgta ttcacgagga
      721 acactttctt cttgagtaac ttcttctata gtagtttcag tagtttcagt ttcttcttca
      781 acgactgtag attctgctac cgattctgca gaagacactt ctgtcacgct ttctttagtt
      841 gtttcagcga cggtattttt agcatcatca ctgcctcctt gcgaacctat agcaataaac
      901 accacaacaa ccgctaacaa ccaaaaccat acccgtttat aaaacggttt cttaacttta
      961 tacattttcc catcttgacc cataactttt tttgccattt aaatatccct cgcttcttgt
     1021 tataatatat ttgtgatctc agaaatgagg tatgagtccg tgttgcagca cgggcttttt
     1081 tctttataac ttttttagag attataggca aaatagtagg gcataaaaat gtattattga
     1141 attccgtatt tagaaaatcc taattgaact tcaccggaag tcttttgctg tgttgtacgc
     1201 aatgcttctt cttcagacat tccattctgt actttccatg caacaggcga catcccgtat
     1261 ttgttaacaa aatcagtaag tgataaagtg tcagcgtctt gctgagcgct tgtttgttgg
     1321 tcttctggat tctgttgaga tgctgcttgt tgttctttct gatcttgact gataatattg
     1381 ccagcatcat ctgtagtcaa tccattttca taaagggcca cgccgaaagc ttcccactct
     1441 ttgttggacc aatttgcacg atcagctgga gttgactgta aagtgcgttg tttcatctgt
     1501 tcatatgttt cttcttgagg tgcggtttgg attgtactct gactggagct tataactgtt
     1561 gggctaggtt ccgccgtagc ttggttggag cttgtaactg ttgaactaga atctgtttta
     1621 gatgtagatt tgctagtaga tgaactggtt tcagttgttt cttttgtttt acttattttt
     1681 gtttcttggt tagaagtggt atctgttgat tcagcttttt tattatttga acaagctgaa
     1741 agtagcagag cagtacttaa caacaacata acgctaactt ttttcatttt ataattcctc
     1801 tttctcgttg taatatgtgt gctaacacgg gcttttttat ataagaaaac gataagcgct
     1861 ttctggaagc ccgtaaagat tctttaattc ctcgattttt ttaggatatt gatcattatc
     1921 ttctttataa agagaaacaa tgagattagc agcaaagcaa ttagcttcgc tttcagattt
     1981 gcttctagat gttcttgttg atacataata gctggataag ccacgatgaa aaatagcgtg
     2041 acctaattcg tgagcgcaaa tgtagaatct ttcctcagag tctcgcagtt catcatttaa
     2101 aaagattatc gcacgatctc taatttcttg aaactgcccc ttgggattct cgataaaagg
     2161 aacgtattga attttaatgc ccatcttttc acaaatataa aaaggattag cggactggta
     2221 tttccgcttc aactcctcga ctaaattaat cgtatccatc tccataagct cacatctttt
     2281 tgcctttttc tttgtcttct ttcacaatat cccagaaagt cgctatcagg atatctttta
     2341 cgcgctgtat ttgttcgggt gtcaatgttt ccccaccata agacatatta acatttgagt
     2401 ctagtagttt atcaagttca accacttcct cttttgtagc ccacttggga acattattat
     2461 ttcccaataa ataatcagtt gtgacaccaa aataatcagc aactttcttt aagttctcag
     2521 attttggcga ggctttatcc catcttctta tttgtccatt agagatgccc acctgtcttt
     2581 ctacttctgc tatagtcaca tgcttttcgt ctgctaattc tttaatctta gtaactaaac
     2641 tcattattat caacctttca aagctgaaaa gaaaataaat agcttaaaag ttatattttt
     2701 ggttgacaat tagcttttaa gctagtatat ttaattcgta agctaaattg ttagctaaat
     2761 aagagcaaca aaaaactcta ctaatttaaa acattctctc ggtcgccaaa cttagaaatg
     2821 ttattttaga ggctttttat aagtcttatt taactatgta ttcataatag cttaaaagct
     2881 aataggtgtc aacgatttag ctaatttttt agcttacaaa ttatttgttt agaaaggagc
     2941 tatttttatg tctgagaatt tagacttaaa aattcgagcg gagatgagaa aaagaagaat
     3001 gactttcaaa gaactagctg cgcttatcgg tatttcagga gcttatttat cagatattct
     3061 aaacggcaat cgtgatggaa agaaagcaca acagcatatc gaaacagtga aaaaaatatt
     3121 ggacatccga tagggggggt aggcgatgac aaaactaaaa aaacaagatt ttgtaaaaaa
     3181 atataattat tctccatcta cttatcaacg tcgaatgtcg gaactaaaaa atacagcaat
     3241 tttctcagcg gcgtatgaac gggtcacagg acaagaagtt tggatcaata cagaattata
     3301 cgataaattt ttgtctttca aatcctataa caggttacgc acaagaaagg taacacctaa
     3361 agaatttatc gagaagcatt tagttgattt ataaaaaaca gaacattttg agaggtgaag
     3421 gttaatgggt aaattcaaca gagcattagt attcagcgca ccgctaatcg tctatgcttt
     3481 agggctttgg ggaagtagac aagcgttgat aggaacgatt gtgtacatgg tttggatttt
     3541 tatagggctg gatgaagctg agtacaaaac aaaaaagcca gtcgggaggg actgactaat
     3601 gagtaaggac gatattgtat ttctgttaat tatgttttgt gggattggat caataataat
     3661 taatttgtat ttgattatta aagaaaaatt tttcaattaa aatgagtctt ttagctttaa
     3721 cttaaatttt ttttgataat tagctgttct tatgaccatt acaagttttt caccaggtaa
     3781 tatatctttc atatctaaaa cttctgaaaa agcgactgag tagccaggag agattgcttg
     3841 tgccaacggt ataggagata aaaggctact tttatgaatg cttcccatat caaaaccatt
     3901 ggcgtgataa tgtgaacaat taattttctt accgttgtaa agatacgtac attcgataat
     3961 tgagtttggc atttttgatg ggtttgcaat tacgccagta agaatcattc gattacttct
     4021 atcatgctta actaaaaaat aggagagcgt aatttttctt ttatctttaa ataagttata
     4081 gagggataaa aaaaatcctg aaatagaaat gattaaagta atagcgactt ggtaatcgct
     4141 caaaattttt atcaagtaat tcaccacctt tttactcaaa ttatatcaaa aaggagagaa
     4201 gaaataatgc aagaattagt aattttgaaa aataaaaaaa gacacgaacg ccggcaagca
     4261 tgatcgtgtc agggaaataa actatctttc tatattttac cacagaaagg aatgaaccgt
     4321 aaatgctaat tgcaacggat acactagacc gcatcttttt aaaagacgaa tacaaactgc
     4381 gcaatataga tgcgtcagga attttagtat ttgatcttta tgacaatgga aaaattggta
     4441 tctatcaagc aagtgatatt gaagaaacaa accttgcttt cgaacaaatt gatgattctg
     4501 tggaattgga tttagatgag gcaatcctag cttttgaaca aattgcaaaa ttattaaagg
     4561 aggcacaaaa gaatggcaac tctttaccaa ctcagcgagt catatatcaa agtcctggaa
     4621 ctggcagaac aattggatga agaaattctt cgcgatactc tcgattcgat taatgaagcg
     4681 atcgagtata aggcagaaaa cttagcaaaa atagttaaag aagtagaagg gaaagctgag
     4741 ttaatcgata gtgaaattaa acgtctgcag gaacgtaaga catcgctttt gaacaatgct
     4801 aagagtatca agcactattt acaagaggaa atggaaaaga ctggtaaaac gaagattaaa
     4861 ggtgaattat tcaacattgg aattcaaaat aatccagtat cggtcaatgt aatcaatgag
     4921 aacttaattc caaaaggatt ctttacccct gtgcctccca aattggataa aaagcaattg
     4981 aaggaggaac tgaagcacgg agatattcct ggtgctgaac tcgtccaaac aaaaggtttg
     5041 aggataagat gatgaaggag gagaaataat ggaacacgaa aacgtaaaag acgctttgaa
     5101 agctgctatc gaaatcgcgg aagctaaagg aataaaggtt gacggcaaac cagcaactgt
     5161 ccatgacatt caaaatttga cgaaagaaca tctttatttt atcgccgact tgcttggttt
     5221 gtcggaattg tatttagaca aataacccca cacggaagga gtggctaggg tggttgtatt
     5281 acaagtaata gtctgcgtaa cattcatttg gtcgtgcata ccggtttgta tatatatcat
     5341 gaagaagctt cgccctgagt cttacaaatt atacgcaatt tacagcataa cagtagctct
     5401 tgcatttaca ttgtttgcaa tttctaggct tccgttttaa tcgtgggaat gaatttttaa
     5461 tgaactaaat tatctataaa gcaaaaaaag gagaaacaac attgaaaaac aaactagcaa
     5521 aaacaacagc aatcatcgga ctagcactag gtagcggcgt tatcggctac gcagcaagca
     5581 atgcgtttca agatttggac acgatcaaag caaatttcaa cacagtccta caatacggtc
     5641 aaacgaaatc gcaacgtgtg tcagaacttg aatcacagct atccaacaac actcgcacac
     5701 aggagcagct gaaagccgaa attgagcaaa tcaaatcgga caagcagaag gaaattgaag
     5761 ccaagcaacg agaagtcgaa caaaagcaac aggagatcgc tacaaagcaa caggaagccg
     5821 atagcttgcg ccaacaacta tccacagtgc aaaacgacaa ggagcagtta gaacagcgcg
     5881 tgagcgagtt acggcagtat acggatcaaa aggtagggga gttggggaaa tgaaagagtt
     5941 gactatttat gacccaaata tttcatgggc taaacacaca attaaagttt cttttatgat
     6001 ttggggttac aaaggatatg ttacttacaa agtgggcggt aacactaagg gtttatcatt
     6061 aatagctatt gattcagatg atctatatga tgctaatttc gaggataacc cagttaattt
     6121 ccgtgacctt gatgaagatt ggttctctat ggaacttact aacgataaag gcgacagtac
     6181 acttgtagaa gatgaattcg acagactagg tgattatatt gtcggtgttg aaattattgc
     6241 gcacgaacca gagtaggaga gtgaatacaa aatgattaaa agaatcacta tatcagttga
     6301 agaagatagt ggatcaacaa tgcagcatac cgacaatcga aaaacttttt taaccaatag
     6361 aaaggagaat tttgatgcag attaagaagg cgacggatat cgaacaaacc aagggaacat
     6421 atttgatcta cggtgctcca ggaaaaggta aaacttcaac ggctaaatat tttccaggga
     6481 aaacactgat ccttgatatt gatcggactt caaaagtcct tagaggtgag aaaaatgtcg
     6541 atatcgtata tatcgacaac gaagatacct ggaacgactg gggcaacacg ttggctgatt
     6601 taactaccaa ttatgtaggt gtttatgaca acgtggttgt cgataatgtc agcgaattgg
     6661 aacggtgtat tctgtccagt ttaggcgcag aaggaaaaaa caacggcgtt ccttcgcaag
     6721 gcgattatca atatatgcaa tttagaatgg tgaacagcct acgctatatg aaaaatttag
     6781 acagcaacct tatctggacc gcatgggaag aaatcgattt gtggacggat tcggatggat
     6841 cttcttacaa catcgctttg ccgcagatca atcgaaagat tcgaaacaat attttgggat
     6901 tatgtgacgt tgttggtcga ttgatggtaa aggaagacga tgaacgcgga tttattttac
     6961 aagccacaga ttcaacctat gccaaaaatc aattggataa tagatctggc tgtaagcaaa
     7021 gtgagctgat tttagatgga attgtacgac taccagaatg atttagtcga tcgtgcaaga
     7081 caagcctatg ttgatggtta caaggcacca tgtatcgtat caccgtgcgg ttctggaaaa
     7141 tcagtcatgg ttgcagagat cgctaaacga accacacgaa aaggcaacag agtgttgttc
     7201 ttggtccatc gtcgtgaatt gattgatcag atcaaagata cgtttcaaaa gatgggcgta
     7261 gataatcagc ttgtaaattt cggcatggtt caaacagtcg tacgacatct taaaaccatc
     7321 aagaaaccac aactgatcat cactgacgaa aaccatcacg ggttagcagc gtcctacaga
     7381 aaaatctatg agtattattc ggacgttccg cgattaggtt ttaccgcgac acccatccgg
     7441 ttaaacggta gtgggttggg ggatgtgaac gacttgctaa ttgaaggagt atcggctaaa
     7501 tggttgattg agaatcatag attagctcct tatgaatatt atgcacctaa attgatcgat
     7561 acagccgaat taaagaaagc ttcgactgga gattttacaa agaaatcaat ggataaggca
     7621 gtgaagaata ctatttatgg cgacgtgttg aaacattata aaacgttagc agaaggtgaa
     7681 caggcaatag catactgtca cagtatcgat gcaagtaaac acactgctga aatattcaac
     7741 gatgctggtt ataaagcaac acatatcgat gcaaaaactc caaaagatga acgtgcagat
     7801 attatcgaag cgttcagaaa tcatgaaatt aaaatcctat gcaatgttga tttgatcgga
     7861 gaagggtttg atgttcctga ttgttcgact gtaattatgt tgagacctac tcaatcgtta
     7921 tcattgtaca ttcagcaatc gatgaggggg atgcgttacc gaccagataa aacgtcaatc
     7981 atcattgacc atgtgggtaa tgtgaaccgt tttggattgc ctgatatgga tcgtgaatgg
     8041 agtttagata caaaaaagaa aacaaaaact gatagtgatt tatctatcgt tcaatgcgcg
     8101 ttttgttttg gtgcttacga acggccaaaa ggcgataata tttgtccgta ttgcggagag
     8161 ttgcagccga ttgaagaacg aaagtcagag ttagaaatcg atgaatcggc tgaattaatg
     8221 aaagtcggag aaacgaaaat tactttgaat tttgagaaca ataaatatta caacatgacg
     8281 gaagatgaag cagaaagtat agaggactta tatgccatag caagagctaa aggatttaaa
     8341 cctggttggg cttatatggc tgctaagagg aaggggtggt tgtaggaatg ggcggtattt
     8401 ttggtaaaaa agcagaagat gttcaaggtt caataataaa tggcgtaaca ataataggtg
     8461 atactggaaa aagagatagt tcaggcaatc aaattgtaat cgctagaaat aaaaataacg
     8521 aagtttttga atcttctcta tctaatataa aaagaggtgt tgttaacggg acaggcgaag
     8581 agagtggcta cgttaattta aaaaaagcta atgaaaaata ccatgttgaa ggaacttacg
     8641 ttaaggcttt gtctgtcggt ggaacaaaag gcgttaattg ggataaacga agaaataaat
     8701 ggaaagcacg attatatttc aaaggagaat atgtcttaca aaaggatttc aacaccaaag
     8761 aagaagcaat ccaagcacga cttgcagcag aagaaaaata tttcaaacct atcttagaaa
     8821 aatatgaaaa taaaaaggag aatgattaac atgacaggat ttaacttaga cttttcaaaa
     8881 gcgcaacaag ggaacgaaat caaagacggt acgtacgaag tggtcgtaaa caaagctgta
     8941 gaaaatgcaa ctaaatcagg cgcagaattt atcgatatcg atttgatcgt tcgtaacgat
     9001 gtggatcaac cgttccaaaa taaacacatt ttcgcaaaaa tctggaaagc caaagctacc
     9061 ggcaaatata acgaaggtat gatcatggca attgcacaag cgctacagtt ggaagacgga
     9121 aaatcatata acgggtttga tgaattgctg gcggactttg ttttgaaaac cgcctcagta
     9181 cgcgtgaaaa ctgaagagtc aaatggatat aaaaacgtca atgtgaagtc ttgggataaa
     9241 acgaacacac ggggcgtaat gaatcaccaa ttcaaaaatg gtgatgaacc atccttcgga
     9301 ccggaacgtt caagagcgac aacggttaga aatgacaatc ttccatttta attgaggtgt
     9361 aatcaatgta tgaaaaaatt ccaaaagagc ttaaaaatct caaacaatgg tgtgtttata
     9421 agctagtttg ggatgaaaag cggcagaagc acacgaagat cccttataac gccaacaacg
     9481 ggcataaagc caaatccaat gacgagagta cctggtctga ttttcagacc gctctcgctg
     9541 ctattgatca ctacggaatg agtggactgg ggttcttttt caaaccacct tatttcggca
     9601 ttgatatcga taatgctgaa ggtgaagttg agcgatttaa atcaggtgat atagaagaaa
     9661 atattatcta tgaatttatc gaaagcatga gatcctatgc tgagtattct caatcaggta
     9721 ctggcatcca cattattgct cgcggagaat tgcccggcgg aagacgcagg aaaggtgacg
     9781 tagaaatgta ccagaacggc cgattcttcg ttatgactgg aaatgccgca tcaaaatatt
     9841 tagaaataac tgagccgaat ccaaaggata tcaaacgcct atatgatcgc tacgttggag
     9901 atgaaaaaat catccaattc aaagaagaaa atccgctgat gaataccgtt gatttaccgg
     9961 ttgaagaaat tatcaaacgt gctgaatcgt cttcccaagg ggcaagattc aaagtcttta
    10021 tgaacggcgg ttgggaagct ttttattcct cgcaatccga agcggatatg gcgttcgcca
    10081 acgacttggc tttttggacc ggtagagact ttgaaaaaat ggatgagatt ttcagagcgt
    10141 ctgcaatgat ccgtagcaaa tatgaccaaa aaaggggatc ggcaacttac ggagaatctc
    10201 tactaaataa ggcaattgct gatacaaatt ccgtctacaa ccccaaacgg aaatctgatt
    10261 ttaagatttt tatcaaagac caggaacagc caaaagagga aaaatactat tcgtacgacg
    10321 acaccggcaa cgcggatcgg tttactgata tctacggaac gttagtcaaa tattcgtaca
    10381 ttgataaatc ttggtattac tacgatggga aagtttggct acaggacaat accggcgaag
    10441 ttcggaaaat gatcgatacg acagtagaca tcatgggaaa agaaccgtta acgatccctg
    10501 aaggcgcaga cgatgaaacc aaagaagctt tgatgaaagc gaaagaaaaa cacgtcaagc
    10561 gttctcgcag caatgccgga aaaaacgcta tgatggacga attgaaacat cgactatccg
    10621 tattgccgga agagttcgac aaagataaaa cgctgttcaa cacacaaagc ggctatctgt
    10681 ctttgcatga cggtcttcta cacgagcatg agatagacaa aatgtttaca cgtgtttcaa
    10741 atgtcgagta cacagaatcg gtcgattgtc ctatgtggga agaatttatt aatcagattt
    10801 ttgacaatga tcaagaatta atcagatata tccagaaatg tgtcggatat tccctgaccg
    10861 gatctaccag agagcaatgt atgttcatcc tctacggtca tgggtcaaat ggaaagtcgg
    10921 tatttttgga aattatttct gaattgatgg gaaactatgc gatgactatg caggcacaaa
    10981 cgatcatggt caagcaaagc caatcatcag caaacagtga tattgcacga ttgaaaggtg
    11041 cgcggttggt cacttcgtca gaaccgaatg aaggcgtccg actggacgaa ggtctggtca
    11101 aacaattgac tggtggtgat aaagtcacgg ctcggcacct ttatggaaaa gaattcgagt
    11161 tcgaacctga attcaagttg tggctggcaa cgaaccacaa gcccatcatc cgtgggaccg
    11221 atgacggcat ctggcgacgg ttaaatttaa ttccattcac tgtccaaatc ccggatcaca
    11281 aaaaggataa aaatctgaaa tttaaattgc agacggagtt gcaagggatc cttaaatggg
    11341 caatcgatgg ttgcctgttg tggcagagag agggcttgga gaaaccaaag tcggttgttg
    11401 cagcgagtca ggattatcga aacgaaatgg atcaaatagg tacatttatc gaaacgtgtt
    11461 gcgaaacagg tccaggacta aaaatatcag gcggagaatt atacaaagtt tatcgtgaat
    11521 gggcatcaga taatggcgag catactttca ctaacacgaa gtttggcaga gagatttcaa
    11581 agaaatatag caaagaaaaa gctggtggat ttatggttta taaaggaatc acattaaaac
    11641 caagaaaata cgataacgtt agagaacttt ttaaataaat ctggagggtt ctggagggtt
    11701 gagaacgaaa ccctccaacc cttagaaacg ttgatatatc agtatttata ttatattttt
    11761 ctttctttct ggagggtttt aaaaaaataa taaagtatta aagtaaaaaa taaaaagtaa
    11821 attatataaa aaagaatagg tttttgggtc tgaccctcca aactctccac caaaatcttc
    11881 ctaaatgctt tgataccaac gattaaacag tctggagggt tacattgaaa tcagaacatc
    11941 aaatacaaga cgagatcaga attgccttat caaaacatgg ttgcacgatt tttcgatcca
    12001 atgcgggaca agtgacaacg atcgaagggc ggcaatttta cgggatgcca aaagggttcc
    12061 cagatctatg tggacatcgt aattctgatg ggaaagcaat ttatatagaa gtaaaaaatg
    12121 aacgcggtaa gttgcgtgaa gatcaaaaaa ggtttgctga atttttaaac ggtcaacctg
    12181 tactatacgg tgttgcacga tcagtggaag aagcattgaa aattgtggag gaatcatcat
    12241 gacaacagaa gaagtgattc aaatgcgtat tcgaagcctt cagcgtgaga ttgacgatct
    12301 ggaacggaca aaggcagtga tggtcaatga aacggcgagg aaggcaatcg atttgcacat
    12361 agagaattta agaagggaaa tccatcgatt ggaggaatga gcgtggataa gaaagcagca
    12421 atgaaacgaa tcatcgaact gacacattct gagaattggc aagaagacaa agaaatagtt
    12481 gcagaagtcc aaaagctcgg taaatcaatg tggagtgaaa aaaccaaacg gagaacaccg
    12541 agaaaaattg caatctggca tggtgaccga attctagtaa caggtactgc tgaacagtta
    12601 tctgaaatta ctggattaag caaaaacatt atctgggata gagctaaacg cgagaacgtt
    12661 gattcgaaag gtcgtcaatt taaacattgg gagaagaaat aatggaggaa ctaatcacaa
    12721 aagtagagca gtgggcaaaa gataagggat tggatcaagc tgattccagc aagcaaatgt
    12781 taaaaacgat cgaagagatt ggggaagttg ccgcttctct agctagaaaa gatgaatatg
    12841 gtttaagaga cggaattgga gacgtagtag taaccttgat tattttagct atgcaaaatg
    12901 atatggattt gtacgagtgt ctgaaccaag catacaacga aatcaaagga cgcacaggaa
    12961 aaatggtaga tggtgtattc gtgaagtcga gtgatttgga ggacagcgat gaataaaaaa
    13021 gtattaattg ataaacaagc attgattgat gaattaatga aaatacctgg tgtgggatct
    13081 aatagtgacg ctttagaaac gattaaacgt ttcccatcgt atgaaccgca gaagccagtt
    13141 gtgcctaagt ttgtggcgga actactcgac tattatcgtc agtcaacaga tgttgattta
    13201 ttagctttat tgataacttt ccatgattgg tattatcgca aaactaaaga cggtgagcat
    13261 gaagaagcaa ttgattggct agttgatcat cctgaaattt atatgcgtgc atggctgttt
    13321 ggctacgagc tcgagaaaga gccgttgtat tgcgtaataa tcaatggtag atatcttgtc
    13381 aaagtattca gcaatacaaa cgttgtcata ttagttccag cagatgaatt ttcacagtac
    13441 gttactcaaa aatttcaatt aactgaaaaa caaatcaaag caattgatga aagatactgg
    13501 ccgtttgctg tgccagtgga tgaggtggta gaaggatgag cgacccatac attactaaat
    13561 tagaaaagtt gtccgaagat tttgagaaga ataaaaataa actaactaaa gataaactta
    13621 tagaactggt taggttggtt atcagaggag ctattacaag agaaaaggcg cagcaaaaca
    13681 tagaaatttt tgctcgtagt gtccgagatg gattagagaa gaaagttaaa caaaatgaac
    13741 aacagacacc gcagaataac aaaactaaga aaacgggaac tgaatgtact aaagacaaag
    13801 tttgaaaaag aatatggaat ttcagcagaa gaaacatata aagtggcaag tcagtgtgtt
    13861 gctgatgcga gcggcgctat tcgtaagttt ggaatttcga tattaagtga tgatcgtaaa
    13921 tgggaggaaa aagaatgaaa ctaaaagacg gattttactc cagcagtcat ggtatcggcg
    13981 gtttaatgct agatatgccg acaaagaacc ctaaaacacg tgagaaacca aaattcaaag
    14041 tcggtgacat ggttcgctgt gaagcagaag gattcatcta tccattttgt ggatatgtag
    14101 aacatctcta taatcactca gcaatcattc gtattgaaaa cacgatggaa tgtgacaagt
    14161 ggttagcgaa aagcaaagag aatttagcag tagcgagatt ggtggatatg gaggttatat
    14221 aaacagcgaa aaaatgtact tctaagagaa aaatttattt tttataaaaa taggaaagta
    14281 tcattatgaa aaagaccaca gagataaata aacctaccac ataaaaaatg aatatttctt
    14341 gcgattcaat ataggtatat ttaacaattt gtacaataaa aaatactata ggtaaaaaag
    14401 ataacatgag gagcttattt gttctagagt gtttgacaaa gtaacaaaat gcgacgatac
    14461 caatacaaac gggaatccaa aataacagca tgctccacat agtcactcaa ccatctccta
    14521 tacgctttat tatcaataga taatatcatt tttcgtaata aagataaaaa aataagtaag
    14581 gcttctcatt aaaatataaa aaagacagcc gaccactgac tgcctatata agagtattga
    14641 aataaaaagc tgctgatata ataaattcca caagtttatt atatcacata aaggagcggt
    14701 ttgacttgat gcaattgtta cgagaggtag atttcaaaca gacaagatgt aatgcgagag
    14761 atgtgctgaa gaactttcgg cgtttggagc ggatggcagg tcgctctttg atagatatta
    14821 agtcgccgat tattacggat atgccgaagg cgccgaagca cggcaataag gcagaagacg
    14881 caatcattca gatgatggat atagaagcgg agagagacgc gattctagca gccttgatgg
    14941 ctcttagtct gattagtcgt cagatactct actatagctt ttgtgtgcca gatagcttct
    15001 caaactacag aattagccgt gaagtgggtt attcagaaag aagtatacaa cggatgaagt
    15061 cggaagctct aatagagttt gcagaagcat ataaacacgg aagaataatt gcttataaat
    15121 aatttggcgg ctttttggcg gaatgatggc ggtttttagc tatttaccag tgatattatg
    15181 gtagtgtcga aagattagtg ataggtctaa gacaaaataa taataaaagg aacatcgttt
    15241 tattattgtt tcacaattaa gcttcgatag acagcaacgg aaatattaag aataaggatg
    15301 tgaattttaa ctccttctaa attgttctta ttatctatca tccgttgctg tctattgttt
    15361 ttttaattat tcacacgata actaaaggtg agcgaagaga aatgattcca ttaataattt
    15421 caatttttgc gctttgtctt aatgtctata tgattggatt taaaaatggg caaaataaaa
    15481 gatagtagta actaagaaag aaatttttat attgtcactg tggcggaaag ggtagacgct
    15541 aagcatgtgt gctaggtcaa tgcttcggca actatgcaat gttcgattca ttgccagtga
    15601 ctttggcaac cgaggcatcg gcggtttaaa aatatagggg tgcgcaattt cgtacgcgtt
    15661 ttgtgcatcg tgtaggttgc tattacatat tagatcactc gttgagtggt ctttttattt
    15721 tacataaagg aggtaacaac gatgtataga ccacaatact tagaacagaa gtatgaagta
    15781 atcactgtgc aaaacggtaa cggtgagata gtacgaaagt atagaagacc aataaagagc
    15841 gatacatata aacgaaagga aaacaatgaa gttatttctt ttcgcagaag gagaaaagcc
    15901 aaatgagaaa ctactggtat gtatcgctaa ctaatgaata tcctcgaacc attgatgatt
    15961 gttcagtgcg tgttgtgcgt tctgtacaaa tcaaagggaa gtactctatt gtcgaaatgc
    16021 taagagaagc tacaccaaac gaagtggata aatgcaagct gatatattgc ggtcatggct
    16081 attggaaaga cgagtatatc caacaaaaca ttgagaggtg gatagataga tgagttacct
    16141 cgaacatttg aaacgttgct acatgcattc taagaataaa cttcctgaca gctacactgt
    16201 agatgatgtt gctatacatg tattgaagac tgagagccat agcagtcctg atggtagcag
    16261 taaggagcag acgctcgcgt ggttcaagtt ctttaagtgg attaaggagg aagagtaatg
    16321 cacatgcaca taggagaaaa gatatataaa ttgagacggc ttaataacga aacaatgaac
    16381 gacttagtta aacaaactgg agtgtcaaaa tcatggttat ctgatattga gtctggaaaa
    16441 aagcaacgcg ttgattttaa taagatatgt gcaatagcca aacattataa agttagctta
    16501 gaatactttc gggatgatta tttggatagt gatgaacacg aggatattat tcctttgaca
    16561 ggcgaaacaa gagttaaatc agtgaaatcg cttgaacaaa gcctaaagta tctgaataac
    16621 aaacaagaac ctaaccttct agagatcaaa ctaaaagata ctgactcagt accagaggtt
    16681 tggtacaagg gtgagaggtt ggatgaattg cctaaaggat tagtagatgt ctcgtatcat
    16741 tggaagactg atgattttac taatgatgat agaggagcga acgacatcac gattcaatac
    16801 ttttctagct ttaatgataa gtatccagat aagaaaacaa tcggacacaa gagagatatg
    16861 taaatgaaag aagttagacc tagagacgaa atagacaaac tatacaagac caaacgatgg
    16921 cgagacctaa ggcaagtagt aatagctagg gacttcggca tgtgccaaga gtgcaagcgt
    16981 cgagggcgga acacaagggg cacgatcatc catcacatag tcgaggcgag ggaagacctg
    17041 tcactgttct ggtccgtaga taaccttgaa tgtatctgtg tagcttgtca caacagagag
    17101 catccagaga gatcaggcgg gaagaagaaa ccaaaaccta aatcacatat cgttaaaatg
    17161 tattcaactc ctgaaagata agtttgcagc gaaatgaagg tagcccccct actctaaaag
    17221 attaaagagt aaggcttgag aagaacggtg ctgtccttcc ttcgtaaaaa gaccgctttt
    17281 caagtttttt ggagaaaaag gaaaaagccg accaatttaa gccggctttg gacgaagcta
    17341 tttcttagtc catttgtttc ctttttgaga agtagggggt aatcggtcgc ctggatcaat
    17401 ttttacttct tgtccgcctt ggacatttcc accacgagga cccacttctt tgtaggttcc
    17461 ttttggtttg ttgtcttcgc cgggtttata gagttctccc ataggaatcc ctccttaaca
    17521 aatttcggca cagcactgcc gataacctaa ttataaggat tgtgataacg atttcaatct
    17581 atcttttgaa agaaggtgat attatgccgc aaccagcgaa gagtgcaaaa ttacaattat
    17641 taaacggaaa cccaaataag aagaataccg aagaactccg caagcgagcg gccgcagaag
    17701 acaaattaaa aatggctact gacaaaatca aaccgccgtt atggctagat tcgctaggaa
    17761 aggatacctt tgagtttatc gccgatgaat tgctgtctgt ggatttaatc agtaatccgg
    17821 acgtccatac aatggctcta tactccaatt ggtattcgca atacgtttct ttagaaaaac
    17881 agcttcgaaa actacaacga gagtacaagt tgaactatgc gcttgcgaaa aaggaggcag
    17941 aggcgagagg tgagccgttt aatgaaccta atgaattaat tggtaatccg ctctctcggc
    18001 agatggatac agcgtctcgg aatctccgtt cttttggcgc tgatttagga ctatcaccag
    18061 cagccagagc taagttagct attaagatgg ctgatgatgg tggtgatgac gatgacgact
    18121 tctaatattt tggatatgtc ttacacagaa cgtgtggact attggcaaag ctatcttgag
    18181 gagcaagctt cttggggtgg ctttttaaaa tgtccatatc cggaattgtt aactacttgg
    18241 tatgcggaac gattaatcga tggaagcata ccagccagca aagaaaatat tcaagctgct
    18301 aaacggcata tgcgtgattt gcagcgccaa ggaacagatg attttccttg gatctttgac
    18361 gaagaaaaag gtcaccggcc tattagatat atcgaaaaaa aatgtaaacc aactgaaggc
    18421 gactttggtt cgtttgtttt gcaaccttgg cagcatttca taattggatc catgtacgga
    18481 tgggtacatc gtgatacagg agagcgtcgc ttccgcgagg ctcttatttt tgttggacgt
    18541 aaaaacggta agttttgccg tttaaaaatc gggcaaaatc ggtgaaaacc tttatttttg
    18601 gctttctttt agtaataatt cgatagcttt atcaagcaat ttagacatag gaaccatagt
    18661 ttcttccgac atttttttta atccttcgta taaatcttta tcaattgcgt tagaaattct
    18721 aattctgttt tttagtccgt atttgtccat gtgtgacact cctttttatt ttactataac
    18781 atccgattcc accgcttgca actaccatca attgatggta gtatataaaa gaggtgagta
    18841 gattgaaaaa atacattatt tacaaacact taaataaaat aaatggcaaa atttatatcg
    18901 gtgtcacaaa tgatattggc agaaggtgga ggagcggtgg gattgaatat aaaccaccaa
    18961 agaacgaaac ccaacaccac agaagttttt ggaatgcaat acaaaaatac gggtgggaaa
    19021 attttgatca tttgattatt gaagaagact taacgatgaa agaagctttt gagaaagaaa
    19081 agttttatat tgaactttat gactcaacta ataagaaaaa aggttataac atcgcaaaag
    19141 gcggaaatgg cggaataata tataaagttc accccaaagg aatgctaggg aaaaaacaat
    19201 ctaaagaatt ttcttcaaat cacagtaaat gggcaaagaa ccataagaat aattgtatga
    19261 caaacggtga tgttgtatgg ggtgttactc acgaacaccc aaaaggcatg ttgggaaagc
    19321 accacagcaa agaatcaatt atgaaaaaga aagcatatag tggtgaaaat gctgtaacct
    19381 caaaaccaat tgtcgcaatt gaacgggatg gaactaaaag agaatttcac agcgctaagc
    19441 tttgcatggc ttactattcg attagtacat gtgtttttta ccgactttta aaagatggcg
    19501 ccccttatgt gataaatcct aaagcgaact acagaaataa agaaaaaata ttagctatcg
    19561 aaggaattat gttcaaacat aaagaagata ccgaggtaag ttagtagatt gcgaaaggtt
    19621 actaactacc gtaacgcgta ggagttgaat aaatataatg ctcccaagag tgtccgacag
    19681 cagataattt gctgaaaatg tacgctaaac tgggccagaa ctgactgacc gatgaaaatg
    19741 agggtgacct ccagagtgcg agataaaaag ctcgcagata ataacaatcg aaaacatcac
    19801 taatttcagg cctttccaca tacatggtcg cttatgatga tgaacaaggc gccaacgttt
    19861 acgtattggc aaatgctcgt gatcaagcaa gcttgttgtt tgataaggcc gcagaaatgg
    19921 tcaaacaatc gccggcgctc tttaagaaat ttggtaagcc taaacgatca agtattaatt
    19981 atgctcccgc cttttctaaa atggaaccac gcgcctcaga tagccggaaa ttggatgggc
    20041 taaacactca ctttggtatt tttgacgaga tccacgagtt tacgaattac aatctgatca
    20101 acgttatcaa gaaatcaaga ggaaccagaa aacagcctct gatagtttat atcacaactg
    20161 ctggatatgt attagatggt ccgttgatgt cttattttga gcaaggtgtg gactgtttgg
    20221 aacatttgga agatgacatc gatgaacgga ctttctatta tctggcaaaa cttgacagtg
    20281 cggaagaggc tgatgaccca agattatgga tcaaagccaa tccgaatatt tgtctaatga
    20341 attttgttgg catgctagat gactatgtta aggataaaaa agatccaaaa gaatatgctg
    20401 actggattac caagcaattt aacttgtttt ccgatatcga tgagctgtca tttgtcgata
    20461 tgcctaccat taaacgaaac aataaaacca tcgatattga aacgctcaaa ggtaagaagt
    20521 gtgtcggtgg ttttgacttg tccgaaacgg aagactttac cgcagccgtt ttagaatttc
    20581 cgcttgaaac aggcgaggta ttcattttgc aacacacatg gatcccacaa gctagatttg
    20641 atcgagataa caatcaagag cgtatcaaag cgtgggagaa ggtgggagat ctaacgatta
    20701 ttcctggtga ttacgtcaat tatgaatacg tcttaaattg gtttgtagaa aattcgaaaa
    20761 tctatgacat tgtaaaaatc aattatgaca aggccaaggc gctacgatta aataaagaac
    20821 tagaaaatgc aggatttgaa accaacgaga ttcggcaagg gtttctatca ttaggtgggc
    20881 caatgcaaaa cttcaaggaa atgctattgg acggtaaggt gattttcaac aattccaagc
    20941 tttaccgatg gtatctatcc aacgtcaagc tggtgatgga tcgcaactca aactggatgc
    21001 cgtctaagca gtccaagagt agaaaaatag atggttttgc agcaagtttg aacagccacg
    21061 ccgaagtgtt gaatatgttg gttaatcctg tcggaaccgg gaaagtaacc tattactcga
    21121 tttccgattt aatgaatatg taagaaaggt gtggaggaat gagtatttta gatcgtttgc
    21181 gttcttttgg ccgagcgaag ccgaaagcga gcaaacaaga gtattttttg aatgacccgg
    21241 gattgatacc gtatttagtc ggaaaagatg aaatatcaga agggattttt tccgtaatta
    21301 gccgtgtatc gaacgttttt gcgtctctcc ctctcaaaat gatagatgtg gagtttggcc
    21361 aaccggacga ctgtcctgca tacaacttgt tgagcgaagg ccctcgatat tttacaaagt
    21421 ttgatttttt ccgggacgtg gaagttttga gaaactacca agggaatgcg tatgtgcaga
    21481 ttttccgaaa tatcaatgga gaagtagcag atatggcgtt agtaaaacct ggtgcttgcc
    21541 atccagtgat tgatatggat agcggggagc tttactacca agtaactgcg actgacaaag
    21601 gcagttacaa gcaagttatc tatgtacatt acatggaaat gcttcacttt aaacaaccga
    21661 ggtttggcgg cttggaaggt acagacccca caaaagtatt aacgaatacc ctcggatatg
    21721 atcgagaagt ccgaaaaatc tctttaagtc agcttaaagg aagtaatgaa gggctaaaag
    21781 ttaagtttgc tagcaatatg gatgaagaag ctaaaaaagc tacagttaaa aacattgctg
    21841 atttttatcg acaaaacggt ggactacttg tggaagaaaa cggtgtagaa atcgaacgtt
    21901 tacaacgaga gctggtagac agcaagcttt tagatactga taaagtatct cgctccagaa
    21961 tcgctatggt ctacaatgtg ccggagcatt tcatcgggaa taaccagtcg agttactcct
    22021 ctcaggaaca gctcaatatg gaatttttga cgtacaatct agtaccgacc gttaatcaat
    22081 atgaagcgga actaaataag aaaacactat cgagaaccga aaaagcaaaa ggttatcgat
    22141 ataagtttaa tgtcgcaagt ttgctaagag ctgacactca ggcaagggga caattctatc
    22201 aaatcatgcg acgaggcgga gcatactcag cgaatgatgt ccgaagattt gaggacttgc
    22261 aaccgataaa taaaaccggt atggatgatt accatatttc cggagaccta tatccaatcg
    22321 atatggatcc aacattaaga aaaacaacct cgtctaaaag cgtagccgaa aacggttagg
    22381 tttttttagt ttgcaccgaa gggaggtgga aaaatgaaaa aagtgacgtt aagcggcgat
    22441 gtcgtggata acgataccgc gtggctttat gactggtttg ggatcaattg tatctcacca
    22501 gggaaaattt ctgccgctct tacagaagca gcgggggatg aagtagaact tgatatctca
    22561 tcgaacggtg gggatgtcct agcggcaagc gaaatatata ccgctatccg tgcctatccg
    22621 ggaaaggtat ccggaaatgt tgtgagtatt gcagcaagcg ctgcaagtgt aatcgcttgc
    22681 gcttgcgaac cgcttagaat ctcacctacg gcacacatca tgattcataa cgcatgggtg
    22741 accactagtg gcaacgctga ggaattaaaa gccaatgcag aaatgttaag cagtgtggat
    22801 gagtctattg ttaatgctta cgagatcaaa acaggactcg atcggaaaaa acttgctgat
    22861 ttaatggcga aagatacttg gttaaatgct caaacagcag tagcagaagg gtttgcagat
    22921 gaaattatgt ttgcagaagc accagtaacg gtactcaatg cctctcaacc ggttattcca
    22981 aaaaacgcag taactaagtt gaaaaattta atactcaaag cggaagcacc gcaagaagaa
    23041 acactcttac agaaaaaact aaaagcctta aatggaggga aaaacgaatg aatttagaac
    23101 aattaaaaaa tgcgtgggtc gaggcgggaa gtaaagtctc tgacttaaat gcacaactca
    23161 atgcagcatt ggttgacgat gaaaaaacag aagaagatgt agtaagtttg caagcacaag
    23221 taaaagcagc acgggctaaa cgggacggat tgaaagagca agtggcaaat atggaagccg
    23281 aacaagtctt aaacgtcaaa aaagaaccat tagataaaaa agatgaaaac ttgaaaaaca
    23341 agtttatcaa agactttaaa gcgatggtca atggtgatcc tgctattatg gctactttga
    23401 catctaatac ggatgaatct ggtaatgcta tcggattgac tattcctgta gatgtgcaaa
    23461 cgactattca tactttggtt cgtcggtttg actctttgca agaatacgta aacgttgaaa
    23521 aagtgaccac taccagcggt tctcgcgttt atgaaaaatg gtctgatatt acaccgttga
    23581 ctgctttgga tactgaagac ggtgaaatcc cagcaaatga tgatcctgca ctttacttga
    23641 tcaaatactt gatcaaacgc tatgcaggta tttccacagt aactaacagc ttgctaaaag
    23701 atactgccga aaacattttg gcatggttgt ctaaatggat cgcgaaaaaa gtagttgtta
    23761 ctcgcaatac aaaaatcttg gcagctattg atggaatcaa agcggcacaa aagaaagatg
    23821 ttacagatgt tgatggaatt aaagatatcg taaacgtcca acttgatcca gctatcgaag
    23881 ctacatctat gtttattaca aaccaagatg gcttcaatgt tttagataaa gtgaaacgtg
    23941 ctgatggatc ttacttgtta caaaaagacg tagcttctgc aactggatat accttcttag
    24001 gtaaaccaat caagaaaatt gcttctcgtt tcttgccaaa caaaggtacg caagctactc
    24061 ctaaatatcc actgtacatt ggtgatctga aagaagccgt tacattgtat gatcgcgaaa
    24121 acatgagctt gctgacaacg aatattggtg gtggagcttt tgaaacagac accactaaag
    24181 tacgcgtcat cgatcgcttc gatgtgcaac tagttgatga tgaagcggtt gttttggcta
    24241 cttttacaac tattgcgaac gagacaccgg cgaaagttta aggagctgat tccttatgat
    24301 tcttgatcct aaaatggatt taggcgaaat caaaaacgca ctaaagattg ataccgatga
    24361 tgacgatgtg gaagtaagcc gtgcggcaca agctgcaatt gcatacatta gaggggctat
    24421 cgggaatgat aagccctctt tttataagca agaaaatgaa acggttgatc tgattaattt
    24481 agctatcctg caattagcag atcattatta caacgctcga tcagcaaccg tgagtgggaa
    24541 cttgcgagag tacgatttag gttttacaag cctaatcttg caactcaaag caagttattt
    24601 gctttttgtg gaggaggagt agcgtatgcc ccttatccaa acaggaaatt taaatcaacg
    24661 catcaagttt gtccgagata cgacggttaa ggatgaggac gggcaagttg tcccgacttc
    24721 tacaaccatt cttacttgct gggcaagtgt gcagacacaa cgcctgaacg atattaagac
    24781 gtcgattggt acggctttgg aaggaacact gacgttcatt atccgctacc aacaaaaatc
    24841 agagctgacc aatgatatga aagtgcgttg gaatggaaaa acgtttgaaa tcattacgat
    24901 tacgaaaggc gagtttgcga aggacttcac gacaatcatt gcaaaagagg tttcaaaatg
    24961 agtgtagaag tcgatgcaac cgaagtgtac aaagcgctta gggaagtaaa agcaaacgtt
    25021 caacgagtgg aaagcccagc acttagaaaa gctggggagt acgctcaaga agagttacga
    25081 caaaacacac cttactggga tggaacgaag tcaaacggta aacgtggttc gtatatgcaa
    25141 gaacatgcta agaaccatgt ggttacaagc tcgataaaaa acggattggt agaagtcggc
    25201 tatgacaaag atgtttcttg gcggatgcac tttatcgagt tcggaacaat caaacaacgt
    25261 ccaaaaggtt tcgtacaaaa aacacaaaag caaatcgaaa aacaagtaac acaaatcatt
    25321 gctgacgaag taaaaaggag gctaggactt tgaaaacggc agtatcacaa gtctattcaa
    25381 ttctgaatag caatgaaaaa acaaagaaca ttgattttta caccaatagt gttccggaat
    25441 cagctcaaac agtacctagc cttccagttg gcagaattac agagatatcc ggcaactatg
    25501 aagattttgc aagcaacaat cctttgacca ttcaatttaa cgtacaggta gatgtatggg
    25561 tgtcaaccat gaaagaggtt gatgcctttt attttgccct tgatgaggtt atgaggggga
    25621 atggttggca atgcgcatac acggaacaaa cagatgacga ggacttggaa ggtgcaaagc
    25681 ggattatcaa acgatatgta gcaaatattt cactaaatta aaaggagaga aaatagatgg
    25741 caacagtagg attcgagagc gtcatttttg gcgtaaaaac aggtgcaggc ggcactctaa
    25801 aagaattagt agcagataag tcgaaaggcg gagcgatcga agctaaaatt actggattag
    25861 gcgcaacttc taacacaaca tacgcttcaa acgtaccgtt cttcattgca agtaaagggg
    25921 tttcgtcgcc aaaagttacg cttgacgtgg cagacttaat ggataacggc atttacagcg
    25981 aaatcattgg tgctaaaacc gtggatggtg caaatgtaat tggttcagaa actgaagcgc
    26041 cttacgtgtc ggtagtcatg gttacagcga acaaagaagg aaaacgcttg ttcatgggat
    26101 tgacaaaagg aaaattcagt catccagata tcgacatgaa aacagctgaa gacaaagggg
    26161 tagaattgca aaccgattcc atcgaagggg aattcatttc tgatgaacgt ggctatgtat
    26221 acttaacagc cgtagaatca gaaggaatga ccttacaaaa attcaaggac ttggtaaata
    26281 acaaagaggg ggagtagtta accctgcatc tacaccaacg acagatacag ggacaccaaa
    26341 agaaccagaa ccaaaaattg atacacaagg ttagccattt ttggctagcc ttattttttg
    26401 taaaaacaag gaggaaaaca aatgattgaa ttgcaattga aacttgacgg aaagaaaaaa
    26461 acattcaaac aacaagatat ttccgcacgt gcaatgcgtg agtgtatcaa attttacgag
    26521 aaagcggaaa aagcagacct aactgattta gaagcgattg attcaatgat tgcaattaca
    26581 gcagatattt tccaagatcc agcagttaca tttgatgcta ttttagacgg tttgactgcg
    26641 agcgagttag taccggcatt agaaagtgtt tttgaacaaa taaatgaact gggaaacaat
    26701 gaaaaaaagc agacggcgag caaaaagaaa taagtttttc tgaagctagg aaagcaatgg
    26761 atcaaatcta caaagattta atcgaagcag gttggacgat gagagatgtg gacgaagccg
    26821 actatcatta tttgttacac ctttttggag aagtggagag tggcgaagaa tatgtagatg
    26881 gtgctgattt catcaaacaa tttttatcgg ctgaagactt agtaaaactt gaggaaggag
    26941 gtaaataatg gcaggaaaag gacaaccggc aggaaatatc aagctaggga ttagtttaga
    27001 tagcactagt tttggtaaca cgctggacga aatcaatgcg aaagtcaaac aagctgagtc
    27061 gaatatgcgt gccaatctaa aggcttatga ttcagcagga cgttcatacg aagcacttag
    27121 tcaaaagacg aaagacttgt ctacggttat ggaagggcaa aacgccaaag taagagaatt
    27181 aacaaagcgc cgtgatgaag cgattagcaa gtatggcgag gaatcgaaac aagttgctaa
    27241 ccttaacaca cagataaaca atgctaccgc aaaatataat gcttacagtc gccagttgaa
    27301 cgacacaaaa aaagaattgg tgtattccaa aacagccgtc aatgatttat ctaatgaaat
    27361 caaagaaaat gaacgacaaa tgaacgccga agtaaaagcg ttgaaagccg ctggtgatga
    27421 atctggtgct tttgaagcaa aacaaaaagg gctagccaaa caaacggaat tatccgagaa
    27481 agctatcgaa gaacagcgca aagttgtgaa actgatggct gatgagtttg gcgattcagc
    27541 aaatgaaacc gaagatgcaa aaagggcatt agaaaagtta gaacgacaaa gccaaatatc
    27601 tagcaggcaa ttagaagcac tcaaaagctc cagcgatcaa tcaggaaaag aaatagaaga
    27661 ttttggcgac aagtccacaa ggtcagctag gaaactggac ggactaaaag acaaattaag
    27721 ctcgctaaaa agcgcatttt cgtttggtgc agttgctgga ttagcgcata acgctattag
    27781 cagtgtagta agtggcgtgc aaggtttggt tggcgaagca gtaaacgcat cggattcatt
    27841 gatgaagttt tccaaaacca tggagtttgc taactttggg aagtcacaga tagaaagctc
    27901 gaaaaaagaa atgaaagact acgccgataa gacggtttat ggtttagaag aaattctgaa
    27961 cacaaccgca caattggcat ctaatgggat tcctaactat acagaactaa ccaaggcggc
    28021 aggtaacttg aatgccgttg caggcggttc tagtgataca ttcaaatccg ttgccatgat
    28081 gctaacgcag acggcaggag ctgggaaact aacaactgaa aactggaatc aattagcaga
    28141 tgcgataccg ggtgcttcag gattgttaca agacgctatg ttgaaaaacg gagcttatac
    28201 aggaaacttc cgtgatgcaa tggcgcaagg tcaaatcact tccgacgagt tcaaccaagc
    28261 aattgtacag ttaggtatga atgacggagc agttaaggca gccacttcta cagacacatt
    28321 gagcggttct tgggagcaga tgaaatccac tgtaataaat gggctacaaa gtattataga
    28381 aaaaataggc gttgaaaata tcactggttt catcaacaga gtaacaaaag ggattgaaaa
    28441 ttctattcct aaaattactc aatttatagg ttggttgaga gatattggaa cgtggatcgt
    28501 tgaaaataga gagccactaa catggattgt cggaatcata ggcggaatta cattagcagt
    28561 aaaagcattg aacgtagcaa gtatgttgct ggcaattact ggcggaacat tggcagcccc
    28621 ttttgtggcg attggtgtag cattaggcgc actagcaggt gctttggtga tagcttatac
    28681 aaaatctgaa acatttagaa atatagtcaa tgcggctttt acagctgtga aaaacgtagt
    28741 tatgagcgtt atcaataatt tggtggaata ctacaaaatg ttgtggagcg tgttgcagtg
    28801 gctttgggaa aaaataaaag aatgggcttc atggattggc aataaattca ttgaaatgaa
    28861 gaacagcgtt gtgaatacgg ttcagaacct atggaatggc gtgaaaaact tcttcagcaa
    28921 tggcgttgga gatacgtgga ataaggtagt cggttgggta aaaaacattt tcaacaaagc
    28981 aactgaattg aagaacaacg tttctgatgt aatcggtaac ctgtggaatg gtatcaaaga
    29041 cacattccgt agaggtatcg atacggtatt caattggttt tcagaactac caacgaagat
    29101 gaagaatgcc attattggcg gtaaaaacgc cattgttgat gcgttcaaaa gtattttcaa
    29161 cgcagcactt aaagcgatag gtaaaccagt taacgcaatc atccatggag cttcatgggt
    29221 actagaaaaa ttgggcgcag aacctctaca agaatgggat gtaccacaat acgctacagg
    29281 tacaccagca ggtgggcacc caatcaatgg tccaatgatg gttaatgatg gacgtggagc
    29341 agaaacagtt atcacaccag atggtagagc cttcattcct aaaggacgca atgttgttct
    29401 aaacgcacca aaaggaacgc atgtcttgac agcagaagag accgcgcaac ttcaaggttc
    29461 taaagctcct aagtatcgtt acaaaaaagg tactaacttc tttggtaaca tgtgggatag
    29521 tgtgaaaaag gttgctggta atgtaggtca cacaattaaa aacgtagtag gtgacgtgtg
    29581 ggactttatt tcagacccgg gagcgttagc tagaaaagta cttggggggt tagatgtatt
    29641 aggtggattg acaaagtatc cattagaagt aggtaaaggc atcctatcta aagcaacaag
    29701 tgcactgact gaaaaaatca ctgggttgtt ctcatctggt aacttagata cctccgtagg
    29761 aacaaatggc gtctataaat atttggctga tgttgctaag tctgtgatga agaaattccc
    29821 aggatttgtg gcaactagtg ggtatagacc aggtgaccct tattcacatg gtaaacgtaa
    29881 tgccattgat attgcattac caggcgtcac aggaggctca cctagataca cagaagcagc
    29941 aaactacgct tttgacaaat tcgcttccaa aattggttac gtaatcacta atgggaaagt
    30001 tcgtgaccgt tcaggacaat caggtcaacc agcaactggt gcatgggagc catggcccga
    30061 tggagatcac tatgatcatg tgcatttaaa cggtgtgaaa gacccacaaa acactcaaat
    30121 ttcaggagat agcgtgggag gcagtggggt agaaagatgg cgcaatgtag caattagagc
    30181 gttgaaaatg accggtcaat acagtactgc aaacttaaat gcattactaa atcaaatgcg
    30241 tacagagtca aatggtaatc ctaatgcagt taacaattgg gatattaacg ccaaaaatgg
    30301 aacaccatca aaagggttgc tccaagtgat tgacccaaca ttcagacagt atgcaatgcc
    30361 aggattcaac agcaatattt ttgacccact atctaacatc ttagcttcaa tcagatacgc
    30421 actatcaaga tatggctcac taacaaatgc ctatcgtgga gttggttacg caaacggtgg
    30481 aattgtaaac caacatcaaa ttgcggaaat cgcagaagga aacaagccag aaattattat
    30541 tccgttagat aaggctaaac gatcaagagc gatgcaatta ttgtctatcg caatggacaa
    30601 actaggagtt tctcctaaaa cttatggaaa tgcgacaact gtttccagtg attacgaaat
    30661 cctagaagcc attgaaaaac aggcggcaac aacgaatcag ctgttatcgt tattgctggc
    30721 atttttcaaa ggaaatagcc gaactgatag agatttagct ttagatattc agaagatctt
    30781 ggttaggagg atgtagatgc gaactgtatt actgagaaat agaataaacg aagaaattga
    30841 tttgtccaca gaagactatt ttgctactgg gttgagtaat atggggtttg aagtaaaaaa
    30901 agaacatgtg ggacagtggg ggaatttcag agaaagcagt gagagcgttg aaatatctga
    30961 atttcagtca tctgtaatca tttctgtgca tgggtttcga gaaaaagaac tgtacaattc
    31021 acttgtgcag ttcctatcgg aaggtccgtt tgaactggaa tttgcttttg acggcgaaac
    31081 aatggtaaga agatgcagtc taaaatcttt aagtaagact gaaatcgatc cgaaaacatc
    31141 gttactaaca gacactttag aactatattt cacatcaaac tggtattccg taaaacgcga
    31201 aaaattaatt cagcgaccga atgtagtgaa aacacgtggt aaggtttttc cgtataaaag
    31261 atcttatatc tacactcaaa acttgtggga gaaaaaaggt gtattcaaat tcaataataa
    31321 ttctgtatac ctaacgaata gcaaggaacg gatgtccccg ctaaaaattc gtgtgattgg
    31381 gaagtgttca aatccgtatt gggaagtaat ccaaaactca caaatcatcg caacggatgg
    31441 atacttcata gatatgactg aaacacagac tctagaagta tcaagccttt ttgaagatac
    31501 aacggcgatt ttaaaagata ttgcaggggt agaatcttct gtctaccaac aacaggatta
    31561 tacaaaaact aattttgttc aggccccaac tggagaattc agcattgtgt ttcatgttgg
    31621 gggggcagac gtagagattg agttatacga ggagcgtgat ctgttttgat tttagcagtc
    31681 acgctttttc atcgtgattt aatgctttat aacgaacatt tattctctaa cagttttgaa
    31741 tttggtgtgg acgagatcaa cgaagaggct agtagcttta cgatggataa gtacgttcct
    31801 gtaaaaacag gcgattttct actagcaaaa tatattccta gtggaaaatt tgcatatttt
    31861 ggtgtaatta cgtcgcagga agacgaaaaa atcagttgta aaagcttact tagtttagct
    31921 gatagtgaga taccgactgc acgtgtgtca ggagataact acgaagagca tatccggcgg
    31981 ttgattgaat actatttgct gaatgatcca acgaaacaac taaaagatat tttagacgtc
    32041 aaagcagaaa gtgcgacctc tcattcgtat caagctaccg atacgaataa acacaagtta
    32101 agtgcgtata ttctcaatgg tttcaaaaaa tacaacgtaa aatggtattt caagggaatt
    32161 caaaacagaa aaatttatac aggcatacgt gctgtaaatg aatcaattta cattaaagac
    32221 aattcttctg aatttagcga ttgggatgtg tttgttcagg cgccgggcgc tggaaacgag
    32281 aacaagctat taatcgttga taaagcaatg aaagatatag agaaaccgat aatactgtca
    32341 acatggtatt tggacgaaga aaacaatttg acacaagatg gatcgaaaga aaatatcacg
    32401 aaaccaactg tcaatttggt taatatctac gatcaaaccg cagaagataa agcatcctac
    32461 gaagatgtgg caaaatcaga gttgaaaggc aatacgtatt cgcatgaaat caaagtgaac
    32521 gttgtaagaa atgcaaaaaa tttgaatgtc gaaacgattg aaacagggat gtttgccacg
    32581 atttcttata aaggaaagat atacaagtcg gttttgacag cttggcgaat atcaagtgat
    32641 aaggagtttg tggaattgac tttcggaaac ataagaagtc gttttatgga ttattttgaa
    32701 gataatgggg gataaaaaat ggttagcaat gtggatggat atcaatttga aaacgtgaaa
    32761 gtaagcgcag aaaatgatgc tagactttat cacgttttat ataatcggaa aaatcaggtt
    32821 attgatggtt acgatcagtc tatgaattta tcttcaagcg gattaacagt aaaagttgct
    32881 gcaggagcag cgattattca aggtcgtatg gtcgttgttc gacaagaaga aagtataaca
    32941 gttccagcaa actcaagtgg ttatatagca ttaacagtgg atttgacaca agaagttata
    33001 cctggatcta ttcttccaga atcggaagaa tatgaatgga ctaataatca agtcaagcta
    33061 gaatttataa caaaagttat aaaaggtaat ttaaacaatg gtgataaggt ctataattta
    33121 ccactatgct cagttaattc tactggatca actgtttcaa tctcaaagat atcggatagt
    33181 tacgagctga ctctctctaa aggagaaatt ttgtggaggg ggactgcgtt aatgcatgat
    33241 actcaaactg tccaaccttc aaaaaaaatt tggcagacag tttcaggttt tttgttagta
    33301 tggctcccat acgaaaacgg gcaagcaatt gaggatagat atgtaactac gcctttttat
    33361 aaggagcgtg taacttttac taatgtttta ggagaaattg tttcaggatt tgatgactat
    33421 cacaaaaagt ggtttagtaa acgaataaac tataattcga atactaatat atttacaggt
    33481 gcagcaagca atgcaagtgg agataacgca aatatggtgc ttaggtatat agtttctttt
    33541 tagttaggag gtatggaaga gtggcaaatt tagaaattaa attatctgca aataagagac
    33601 agccttatct acgtcaccgt gttgttggta gagttggtga tggggggctc acaacaatca
    33661 atgtacaact tcttgaggaa gatgaaatta caccttttgt aattaatcta aacggtactt
    33721 tgaaatttgt gggcgaagtt tcaaacggta actataccga gggagaacca gaaataatcg
    33781 attcgactaa tgggttaatt agttacacgt tcactaagtc aaatttcagc acgagtcatc
    33841 aattcaaaca agcatatttt gaatatgtag atcctaacgg caaaaaagta acttttcaga
    33901 acttcatcat agacgtgtta gaacgagtgg atattaattc ggagcaagcg aaatactata
    33961 tttcttcatt ggaaaaatta cagagtgaaa tgcaaaccac tttcaatcag ttcattagtg
    34021 ataaacaggt ccaatacgat caaatctact cgaaatataa cgaattagta agattgataa
    34081 atgaatcaga taagcaagta aatgatcgta ttgatcaaac caatcagcaa atcggcgatc
    34141 tcggcaagct gaaaaagatg tacagtaaca gcatcgactt tgggggctat gattattcgg
    34201 ggaatccgaa tttgttaagt aagctatcat acgacttaat tgaaaatcaa aatacttcag
    34261 ctggaacact ttctaagggt gaaaactcgt ttaaatataa taagatatca gctgaagtgg
    34321 aaggtggagt agagttatat tataaacgaa gaggtatagc taactggtta ccctctaata
    34381 aaacgcttgt aatgactgtt aagcttagag ctggagcgga ctatagtcca gttgacggaa
    34441 aacttatact gattagatat aggtatgttg acagtggaac tggcaagatt gttttagact
    34501 tacctattaa cagtaattcg ataactcagg aatggaaaga gtttagtatt actggaacta
    34561 ctccaacatt tagcccacaa gcataccatc cttggataca atttagggct caagatgggg
    34621 tacttgggga aatagaaatg agctatgaca tcaaaatcga agaaggctct acagctacac
    34681 catatcagcc taacttactt gatgactctt actggctagg taaaacaccg ttgggtgaga
    34741 atttgataac gaatgccaag ttcccaatta taacacgaag caatcctatt tctggttttg
    34801 atatttcaga agaattaata ataggtgaaa cttatacggt atctttaaaa gggactaagc
    34861 cagctactaa agaattccac ttatactacg gagaagcaaa ttaccagcag ttgcagtatc
    34921 aggcaacttt acttcctgtg gaaggattaa cagatgtgtg gagtgccact tttacagcca
    34981 gaaatactag tgaaacgaca aatttactta gagtagcgtt atggcaaaaa cctaattctg
    35041 caacatatga tactgttcaa attgactggc tcaagattga aaaaggcgac acacgcacac
    35101 caaatatcag tcagtttaaa tactttggtg aaggcttgaa agacagtaac aatccgaacg
    35161 actacagctg ggatgtcaca ccagagtata ctgaaaaaag cttgaataat acggttagtc
    35221 tgactgaacc gcaatccatc gaaggattga aaaatttcga agatggtatt caatcaaaag
    35281 gaaaatctgt attgacatca gacgacaaca aatatgaagt cgtaacctta acagttacaa
    35341 acgggaatac cggatcagca aagctttatc gtgaaggaaa aaccgtcact atttattttt
    35401 ttgcgttgaa tgggaaaagc agtggtggaa atgattcaac gatactaaca attccagaag
    35461 gctatcggcc accaattagt tttgagcaac tggttggctc gatagaccgt tctactttga
    35521 acagtgctca gttatctatt ggtgcagatg gagccattaa atggcgaaga aactcaagtt
    35581 atggatcgga ttataccttt gcaattactt acacgattta gaaaggcgtg aatcgatatg
    35641 aaggcagcat atagaccaat tgaaccttac ggattcgagc aaatcattgt gaatgatgaa
    35701 gaacatttac cggaagaatg cacagaagtc gaaccaccga ttccaaattg gaaaccgaaa
    35761 ttcaattact gggagggaaa taaatgaaaa acatttggaa atatggccgt actggcggag
    35821 agtatgcagg aaaagtattg gacgacatgc ttgtatccgt tccttacaca gatcagccac
    35881 cgctcgaagg ggttcgttca gatggcgaac cgctaacgat tgctgatcag atgtttgatc
    35941 ctaaattgaa ccaatggatt attttagcga acgcgttaga tcacaacgat ttaaacaatc
    36001 tcaaagcgat gtacgaggct cttgaacatg aaaacggcaa cctaaaacag ctaaatgcca
    36061 aactcatgct aagcgatgta gcgattaaac aggaaaatac tgcattgaaa gaaaaagctg
    36121 acagtttagc acaaatcaat tcaaaaatga tgcttgcttc gttacaaaat agcaaagaca
    36181 tttcagaaat taaagagcaa ctaaatccag cttcaaaggg aggtgagtag tatgtttagt
    36241 tttagcgatg tgaaaatgat gtatgattgg ggctgtttta ctgacgatca agttcgtcta
    36301 ttcgttccac tatgtatcac agatgaagaa gcagatagaa ttattagcaa agaagagagc
    36361 gcatcttaag tgatgcgttt ttttgttgga aagttggtgg aacatgaaag aagaagcgct
    36421 ccaagacgtt gtggagagat tagtaagaat tgaaacaaaa ttagacaact acgaatcact
    36481 tagagaaaaa gctgatagtg caaaagattt ggcagacaaa gcctactcag tagcgctaaa
    36541 caacgcagaa gatatcaaag aaatgaaagc caataataaa tggtcgtggg gttacatgat
    36601 cggtttaggc attacgatca ttggctattt cttgactaaa ttgtaaagga gttaagaaga
    36661 aatgatttta cccgataagt attatcaagt cattaaatgg acggttttaa cagtattacc
    36721 agctgcatct gttttagtag ccacgttagg aaaagcgtat ggatggaatg gaacagatat
    36781 gacagtactc actatcaatg cagtagcaac atttttaggc gttatcactg gtgtgtctgc
    36841 atataactta aaaaaatagg aggaaaaaaa tgaagaagaa aatcatttta tcattgagcc
    36901 taataatggc tcttttttta ttgccaatta acgggttcgc ctatacgatc aacaatgaat
    36961 ttaatttagg tgtaaatgaa ggtagctcac aagtagcaaa taaccaatac atcctattgc
    37021 atgaaacagc aaacgaaact gcgacaggac gaaatgaagc gcagtacatg aaacgttctt
    37081 ggtacaatgc ctatacagcg tatattgttg gcgatggtgg gatcgtttac caagttggac
    37141 aacctggtta tgtacaatat ggcgctggtt catatgctaa tgcaaatagt cctgtgcaaa
    37201 tcgaactgca acatacgcac gataaagtaa cgtttgaaaa gaactacaag gcatatgttg
    37261 aattagcgag agattccgct aataaatacg gtattccact tacattagac acaccgtata
    37321 atcaaccagg aatcaaatca catttatggg taactcaaaa catttggggc gatcacactg
    37381 atccgtatgg atacttatca gaaatgggtg taagtaagga aaaactggct tacgatttag
    37441 ctcatggatt tacagacgaa aacccaacga cttctgagaa caagcctgtc attgatccaa
    37501 cccgagcagg tgcagcaaat ccaactttat cagatggaac gaaccattct cacattgatc
    37561 agtttggaga aatcgaaaat gcgaacttac acgtcgctgg atggcacatc gctaactata
    37621 aatacgagta tattttcatt atggactaca atactgggaa agaattagct cgagtaagag
    37681 ctgatggaat ttatagaccg gatgtaaatc aagcttataa tacttctgga aacgttggct
    37741 atcatgtatc ttttaacatg cgcaatttcc ctaataagaa agtatacgtc atgatgcggg
    37801 caacgaatga tccagaagga aacactaaag gcggtgcgca agatttccat gacaaacgtt
    37861 ggtatttaaa tattcctaaa cgataaaaat agctcctcgt tgaggagcag tacatagaat
    37921 tgaaaattaa cgttaaatca aaaaaatatt tacaagatgt ttatttaagt agataataaa
    37981 agaaaaaagc aggtgaaatt gtgacagcag aaattggtat tatgaataaa agtggaatcg
    38041 tgttagcttc agattcagca tctacgattg gagatagcaa agtatataat actgcaaaaa
    38101 aattatttac tttggattcc atgcattctg taggtatcat gatatatggt aatgctgaat
    38161 ttaatggtat tccttgggaa ataatcatta ctcaatataa gaaaagcatt ggtagttctg
    38221 tttttaatac tttggaagaa tacgcggata attttataga atttgtcaaa acagcatctt
    38281 ttattagaag tgaacagacc gagcaagaac aaatgattgg ggtttttcaa aaaataattt
    38341 caggtttatt tgagagtata gaagtagata ttaacttttt aataagccaa ggtacacaaa
    38401 tagacaaaga tgtcctagtg aagttattac aaacaaaaat gaataccaat ttgtctcaac
    38461 agtcccagac attcatttta gatattgaaa aggcgttatt tcttagtaac tatggagaaa
    38521 tattaaaaga tattcttaat agtatttcta caatggaagg tgtttcagaa gctatatcag
    38581 aggaaattca aagttacgtt tatgaaatta taattagaga cgatgtttat tcttccccta
    38641 caggaatagt tatagcagga tatggaagaa tggatatttt ccctaaacta tattcttata
    38701 atatgtttgg atttgttatg aatattctga aatactcaga atatgaaagt gctcaaatag
    38761 gaaatgacaa tggttcatta agatctacta tattaccatt tgctcagtct gatgtggtaa
    38821 atactgtagt tcaaggggta gatccacaaa ttactaatta tctgtcgagt caagtcgata
    38881 gttttgacga taacggaaaa aatacctata ttaatattat aaagaatatt tcagagtttc
    38941 aacaaaatca attcatattt ccgttactaa acatgattgc tttactccca gttgaagaaa
    39001 cagcaattat cgcagagact ttattaaatt taaccagttt taaacgaaaa tatactactt
    39061 ctgtagaaac agtaggtggc ccaattgatg ttttagctat tacacctaat gatggcccta
    39121 tttggattaa aagaaaacat tattttgata ttgataataa tattggatac agattgcgaa
    39181 aggagagagc gaatgattac aataattaaa cctcaggaaa aatcccctgt tttgaaattt
    39241 aatgagagca atctagccca taataaaatg agtataactg atacagtatt tgatgtaatg
    39301 gttgagcaac aaaaaaaaat taataataac aatagacaaa gaaaagaaat taaccaatat
    39361 taatgttttt tctgttgcgt tttttgcagt cataatttaa aacctcgctc aatcttgggc
    39421 gaggtctttt tttatttttc tgaaaagtta aagtaaataa tagcataaaa taatatattt
    39481 tacaaagaat aagtacaatc tagttttttg ctattaaatg tgtaataata aatatgccat
    39541 cacaacatga agaatgaaat ccattattat ctagtctagt ccattctttt tgtttgcagt
    39601 atttgtgatg gctttc
//
LOCUS       DADLIO010000019        37151 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.019, whole genome shotgun sequence.
ACCESSION   DADLIO010000019 DADLIO010000000
VERSION     DADLIO010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37151)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37151)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37151
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.019"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(148..2301)
                     /locus_tag="JOX41_001142"
     CDS             complement(148..2301)
                     /locus_tag="JOX41_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HAY6448899.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(2595..3443)
                     /locus_tag="JOX41_001143"
     CDS             complement(2595..3443)
                     /locus_tag="JOX41_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAY6448900.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(3667..5607)
                     /gene="thrS"
                     /locus_tag="JOX41_001144"
     CDS             complement(3667..5607)
                     /gene="thrS"
                     /locus_tag="JOX41_001144"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HAY6448901.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(5944..6123)
                     /locus_tag="JOX41_001145"
     CDS             complement(5944..6123)
                     /locus_tag="JOX41_001145"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HAY6448902.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(6170..7993)
                     /gene="cadA"
                     /locus_tag="JOX41_001146"
     CDS             complement(6170..7993)
                     /gene="cadA"
                     /locus_tag="JOX41_001146"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HAY6448903.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            8271..10550
                     /locus_tag="JOX41_001147"
     CDS             8271..10550
                     /locus_tag="JOX41_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAY6448904.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(10643..11290)
                     /locus_tag="JOX41_001148"
     CDS             complement(10643..11290)
                     /locus_tag="JOX41_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448905.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(11469..12188)
                     /locus_tag="JOX41_001149"
     CDS             complement(11469..12188)
                     /locus_tag="JOX41_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAY6448906.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(12319..13470)
                     /locus_tag="JOX41_001150"
     CDS             complement(12319..13470)
                     /locus_tag="JOX41_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HAY6448907.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(13687..14427)
                     /locus_tag="JOX41_001151"
     CDS             complement(13687..14427)
                     /locus_tag="JOX41_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAY6448908.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(14431..14754)
                     /gene="rsfS"
                     /locus_tag="JOX41_001152"
     CDS             complement(14431..14754)
                     /gene="rsfS"
                     /locus_tag="JOX41_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HAY6448909.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(14811..15404)
                     /locus_tag="JOX41_001153"
     CDS             complement(14811..15404)
                     /locus_tag="JOX41_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAY6448910.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(15388..16035)
                     /locus_tag="JOX41_001154"
     CDS             complement(15388..16035)
                     /locus_tag="JOX41_001154"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HAY6448911.1"
                     /translation="MNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHLV
                     MAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIELA
                     RGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPGY
                     TTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(16048..16359)
                     /gene="yhbY"
                     /locus_tag="JOX41_001155"
     CDS             complement(16048..16359)
                     /gene="yhbY"
                     /locus_tag="JOX41_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HAY6448912.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(16375..17484)
                     /gene="yqeH"
                     /locus_tag="JOX41_001156"
     CDS             complement(16375..17484)
                     /gene="yqeH"
                     /locus_tag="JOX41_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HAY6448913.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(17481..18008)
                     /locus_tag="JOX41_001157"
     CDS             complement(17481..18008)
                     /locus_tag="JOX41_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HAY6448914.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(18188..18973)
                     /locus_tag="JOX41_001158"
     CDS             complement(18188..18973)
                     /locus_tag="JOX41_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HAY6448915.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(18966..19835)
                     /locus_tag="JOX41_001159"
     CDS             complement(18966..19835)
                     /locus_tag="JOX41_001159"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HAY6448916.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(19836..21215)
                     /locus_tag="JOX41_001160"
     CDS             complement(19836..21215)
                     /locus_tag="JOX41_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HAY6448917.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(21223..21642)
                     /gene="fabZ"
                     /locus_tag="JOX41_001161"
     CDS             complement(21223..21642)
                     /gene="fabZ"
                     /locus_tag="JOX41_001161"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HAY6448918.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(21667..22143)
                     /gene="accB"
                     /locus_tag="JOX41_001162"
     CDS             complement(21667..22143)
                     /gene="accB"
                     /locus_tag="JOX41_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HAY6448919.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(22146..23381)
                     /gene="fabF"
                     /locus_tag="JOX41_001163"
     CDS             complement(22146..23381)
                     /gene="fabF"
                     /locus_tag="JOX41_001163"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HAY6448920.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(23400..24137)
                     /gene="fabG"
                     /locus_tag="JOX41_001164"
     CDS             complement(23400..24137)
                     /gene="fabG"
                     /locus_tag="JOX41_001164"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HAY6448921.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(24149..25066)
                     /gene="fabD"
                     /locus_tag="JOX41_001165"
     CDS             complement(24149..25066)
                     /gene="fabD"
                     /locus_tag="JOX41_001165"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAY6448922.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(25173..25397)
                     /locus_tag="JOX41_001166"
     CDS             complement(25173..25397)
                     /locus_tag="JOX41_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAY6448923.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(25450..26412)
                     /locus_tag="JOX41_001167"
     CDS             complement(25450..26412)
                     /locus_tag="JOX41_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HAY6448924.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(26422..26862)
                     /locus_tag="JOX41_001168"
     CDS             complement(26422..26862)
                     /locus_tag="JOX41_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAY6448925.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            27168..28133
                     /locus_tag="JOX41_001169"
     CDS             27168..28133
                     /locus_tag="JOX41_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAY6448926.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(28190..28420)
                     /locus_tag="JOX41_001170"
     CDS             complement(28190..28420)
                     /locus_tag="JOX41_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HAY6448927.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(28506..29393)
                     /locus_tag="JOX41_001171"
     CDS             complement(28506..29393)
                     /locus_tag="JOX41_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HAY6448928.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(29482..30705)
                     /locus_tag="JOX41_001172"
     CDS             complement(29482..30705)
                     /locus_tag="JOX41_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAY6448929.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(30722..31801)
                     /locus_tag="JOX41_001173"
     CDS             complement(30722..31801)
                     /locus_tag="JOX41_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAY6448930.1"
                     /translation="MLYYISEGGRKVKVLLYFESEKMLAKSGIGRALDHQKRALTEVG
                     ISYTLDEKEDYDILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQL
                     SPIVKKYLVGLYQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQ
                     KFREYFKLSPDQKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIR
                     KIVKEDHPENVLFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVR
                     DIPVYNGWLEDSKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEE
                     LKNVYESVLNEKVSSKLKKVNQVKD"
     gene            complement(31932..33659)
                     /gene="ptsP"
                     /locus_tag="JOX41_001174"
     CDS             complement(31932..33659)
                     /gene="ptsP"
                     /locus_tag="JOX41_001174"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HAY6448931.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDTMEEV
                     VELVHEYVK"
     gene            complement(33659..33925)
                     /locus_tag="JOX41_001175"
     CDS             complement(33659..33925)
                     /locus_tag="JOX41_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HAY6448932.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            34404..36638
                     /locus_tag="JOX41_001176"
     CDS             34404..36638
                     /locus_tag="JOX41_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAY6448933.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            36786..37106
                     /locus_tag="JOX41_001177"
     CDS             36786..37106
                     /locus_tag="JOX41_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HAY6448934.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPQH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
BASE COUNT        10450 a         8038 c         6479 g        12184 t
ORIGIN      
        1 ttttgtcaca accttttttg ccgagtaaac ggtgttcaaa agccagtttc tcggtatgaa
       61 gtcaaattta agcaaaaatg tgagaagcta ttttcacaaa atttttcttc atactcgaaa
      121 ctaagcggct ttttcacgac ctctttttta ttttgccatg aacatatcat aatacgcgtc
      181 cattatttct ttagcaatcg tcaagtttat gtggtcttgt tcgtctaata agttcggcaa
      241 gacaacactg atggcaattt ccggattgtc tgttggtccg tatgccacga tattactatt
      301 gactgtcgca atatctggat gaccttccgc aaccgtttct gcagtccctg tttttgcgga
      361 aaggtccatt ttcgcactgg ctaatggttt ggctgttgtg taaggatcgg taccatggac
      421 aacttggtgg aatccttcac ggaggatcgc catattttct gcagaaatat tgaccgtatt
      481 ttctactgtt gtgccaattt ctttcttcac ttcacccaag tttccatttt cgtcattgcc
      541 atagatcgct ttgactaggt gcggctgtac tcgtttcccg ccattagcga ctgttgaagc
      601 atattgagct aattggattg gtgtatatgt gtcaaactgt ccaaatgcca aatcggtaaa
      661 gttacctgga gcataccatt ctttgccatt atccgcattg aacttcttca tataatcaac
      721 agaacgtgag atcccaggag attcattcgg caaatcgatc ccagtcgttg taccaagacc
      781 aaactctttg aaagagtctc tcaattgctg ataagcttta gcttcttcat ctaaactagg
      841 tagtcccatt ccaggtgtat agtctagtcc taacatcttt aacgccactt tgatcatata
      901 cgtattagaa gacaattccg atgctttgac tgcatcaaga gcaacttgtc cgcttcgatt
      961 aaagacagag cttttttctg aagcaccttg cagacgaatc ggctcatcaa tcaaaacttg
     1021 atttccgctg atcgcgttac ttgcccagcc tgctgtcaaa gtaccagcct tgactacaga
     1081 ccctggatca aaggcgctag taatcgtgcc taaagcattc tcggtgattt ctttggaacc
     1141 ttgttcatga ctgaaaccag tcattgctag cacttctcct gtctgaggat tcatagccac
     1201 tgcataagca ccaggcgaat actgtgcttt gccgttgttg atcaatgttt gataattcct
     1261 tttcaaaatt tcttctactt ttgattggaa ttctgcattc atagataaca ttaaattaga
     1321 acctttttcc ccagagaaga tttctttttg attcgaaaca tttccttcat tatcaaggga
     1381 aacttcatat tgggttttgg ttccttgcag gacatcttca tattgttttt ccaaataact
     1441 ttgtcctaca cggtcattcc gagaataacc ttttgctagg tatttctctg cttcatctgc
     1501 tggaagtcct tgcttttcag tcgtcacact gccaagaata cttttcagtg aacttgctgc
     1561 attatattct cgtgtccagt ctgtgccagt cgaaactcct ggaagttcag aagcgcgttc
     1621 tgccacaaca gctaactctt gatcagtaac accagagttt ttgatataga cagtgtttaa
     1681 ttcatatgca ctattcatcc gtttaaagat ggtagcaatt tttaattgct cctcgtttaa
     1741 attaatctca tcagctgtga ctttattgac catcgcacta tattgttcgc tgttccctaa
     1801 ttgcttttct tttgccgaaa gtctttttgt ggcttctttc aaatgtttgg gatcagccag
     1861 ccaaaaatct tttttatctc tatctgtcag attttcatct accggaacat cgatcagcga
     1921 gttcagcttc gttgcgattt caagcaaatc tttagccgta acttgtgttc ctctcgtata
     1981 tgtgatggcc tgattcgctt tattcgtaac taaagctttt cctgtggagt cgtagatcat
     2041 tccgcgagga gtactttctt ggaccgtaat cgtagaagta gacttcactc gcgcctccat
     2101 ctcttcgccg ttcacgatct gcaaataacc caatctagca atcaacgcaa caaataacgt
     2161 aaatataatg aaaaaaagaa aatttaagcg aaaaggaaca tgggaccggc gaaacgtttt
     2221 gttcttaggt tcttgtgcac cttttcttat tttttctaac caagaagtat ttaatatttt
     2281 tttcataaaa tctttcatca tttcctatcc ttccgcctat ttacattcat gcttcattgt
     2341 acccaaaaac ttcttaataa aaaagaaaaa atgggcggag caagaaattc tttacctaat
     2401 ttcaagataa aatcaacttt ttgtttcaca gcaatcactt aaagttacat atccaactat
     2461 ttttttcatt aaaaaataaa cttatttttg aaaattatgt tttcttaagt cgtgaaacac
     2521 tttgatggat catttatttg tggaaaacta cgttttgtta ttctaaaaaa cttatataaa
     2581 aaatagtaag gtttttattt cgaatccata aaatattctt ggattgcttc tcgtgttttt
     2641 ttcacttttt cgctaagctt ttcgttttta gccatataga aataaaaaat gatatcgatc
     2701 gtagcaaatt gggccaaaag tgaattagtt gccgcacttc gattcgtgat ttcttttggt
     2761 ctagatgttt gtacgagtac atcggctatc ttgctaagcg ggttatttcc aaattgcgtc
     2821 aacgcaatga tttcgatatt catgcttttc gccagctcgg ctaatgcgac tacatctgca
     2881 cttctacctg agtttgaaac aagccaaagc actttctttt tctcattgct gacaagttgc
     2941 gggagcaaga cgtggatatc tttttcaaaa atgattggct taccgacacg agaccatttt
     3001 tgcagaatat cttctactac taaagaagag gcgccaaccc catataaaaa aacagtctct
     3061 gccgattcca aacactctac gactttttgg atcgtttctt cttctagaat atctactgtt
     3121 tcttttatcg ctacttgtgc attgttacca agtttgtttt tgatagagta aaaggactca
     3181 tttgcttcta tatcactaaa accttcatcg attccagtct gtagttctgt tgaaatcgtg
     3241 attttgaagt ccgtcagact ttgaaaaccg atttttttgg aaaaacgtac aactgtcggc
     3301 gcactcaacc cggaagcttc tgctaattca ttagctgtca ttgtagggac cttctcaata
     3361 ttaccgataa tgtagttggc caactttttt tctgctgaag aataatcttc catcatactt
     3421 tcaatacgac taattacgct cataagttcc tccacccttt taatgatagt ctatgtaagt
     3481 ataccatatc agacccttat tcacggtcgt atactggata aaaaacaaaa aaacaatccg
     3541 cccaacagaa tatcttatcc catcaatccc acagattcta ttgagcatct gtgtctttga
     3601 ggaatacctg ttatctattg ttcggattgc tttctatcta ctactttttt acaggaaatt
     3661 tacctattag ttttctctgc tgtaattttt gacttctgct tccatagcat caataaagat
     3721 attcaaatct tctacagctg tttctttact tccataacga cgtacgttca ctgttgcatc
     3781 ttccaattcc ttgtctccaa caactaattg gtaagggatc ttttgtgttt gagaggcacg
     3841 tatcttatag cccatttttt cattacgatc atcaacttct acacgcaacc ccttcatttg
     3901 caaacgttct ttgatttcat aagcataatc gccatgtgca tcaacagaaa cagggatgat
     3961 tgttgcttgt ataggtgcca accatgttgg aaaagcgcct ttgtatactt ctgttaaata
     4021 agcgacaaaa cgttccattg tagaaacaat tccgcggtgg ataactactg gacgatgcgt
     4081 attttccccg tcttctccaa catatgtcaa atcaaagcgc tctggcaata agaagtctaa
     4141 ttgtatagtt gataatgttt cttctgtacc aagagctgtt ttgacttgaa catctagttt
     4201 tggtccgtaa aaggctgcct cgccttctgc ttcaaagtaa tctagttcta attcatccat
     4261 agcggctttc agcattgctt gggctttttc ccacattgcg tcatcatcaa aatatttatc
     4321 tgtattgttt ggatcgcgat agctcaagcg gaaacgataa tctgtaatat tgaagtcagc
     4381 atatactgcc accatcaatt caagcgtacg tttaaattca tctttgattt gatcaggacg
     4441 aacaaatgta tgaccatcat tcaacgtcat ttctcgtaca cgttgtaaac ctgacaaagc
     4501 acctgatttt tcatagcgat gcatcattcc taattcagcg atacgaattg gtaattcacg
     4561 ataagaatgg atcgtgtttt tgtagaccat catgtgatga gggcagttca ttgggcgaag
     4621 aacaagcatt tcgccatctc ccatatccat tggcgggaac atgtcttctt gataatgatc
     4681 ccagtgtcca gatgttttgt acaactcaac atctcccatt attggtgtat atacatgttg
     4741 gtaacctaga ctaacttctt tgtctacgat ataacgttcg atcgtgcgtc ggattgttgc
     4801 cccttttgga agccagaatg gcaaaccaga acctacttct ggggaaacca tgaacaagtc
     4861 aagttctttt cctagtttac gatggtctct ttcttttgct tcttcacgga gacggatata
     4921 ttctttcaaa gctttcttgt caaaaaaggc tgtcccgtat acacgttgca tcatttgatt
     4981 gtttgagttt ccacgccaat aagcacctgc cactgataat aatttaaata cttgtatacg
     5041 gccagtggat ggaacatgtg gtccacgaca caaatcgatg aattcgcctt gttgataagc
     5101 agtaatcact tcttcttctg gcaattcact aatcagttct actttgtacg gatcacttgc
     5161 aaaaatttct aatgcttcct gttttgaaag aacacggcgt tcgatcggca gattttcttt
     5221 gacgattttc atcatttctg cttcgattgc cggcaaatct tctgcagtta cttggttttg
     5281 tccattatct gtatcgtagt aaaaccctga atcgatagct ggtccaacgc caaagtggat
     5341 atttggatag aggcgacgca tggcttgggc catcaaatga gctgctgaat gacggactaa
     5401 gccaagtgca tcttcatggt ctggtgtgat gatctcaata cttgcatctt cctcgattgg
     5461 acgagtcaaa tcaacgagtt ttccgttcac tttaccagct aaagcttttt ttgctaagct
     5521 ttttgaaatg ctttcagcaa ttgccaatgt tgttgttcca gactcaaatt ctttgactgc
     5581 accatctgga aaagtaattt ttatcataat agtttcctcc ttgaaatgtt ttgattgatc
     5641 agatcatcaa gctgaaaaac aaaaaaatcc tagcatctct tgaaaagaga tactaggacg
     5701 aaaagttcgt ggttccacct aatgttcaaa cgcaaatgcg ttcctcaagc gttgtaacgg
     5761 tccgaccgcc cttgcttcaa caagggtttc gaaagtggtc atcctttggt tttctcctgg
     5821 aaaagtttca gcctagcttt tcctctctta tcgaagactc tcaaattcag ttggctttct
     5881 catcaatcaa ttatgtgttt atttaaccac taataaatag aaaaatcaag tgggaaacta
     5941 aacttatttt ttccattccc catttacacc gtatgttcct tttttcatct cattgatgat
     6001 gacatggatg tgttcttttg gtgcctgcgt gtttttatga acagcttccg tgatatcttt
     6061 catcatattt tctaattgtt ccggactgcg accttctact aattcgacat gtacgaatgg
     6121 cataatgctc tctcctcttt ctgatcgttc ttttttcaac tcgattctat catactatgt
     6181 ttgtcttggg tactgaatca ggaaaaatgg ctggatcttt ttttgctctc aaggcactca
     6241 aaatagagac cgtatccacg acttcttgca aaacagctcc gaataatgcg gggattagtc
     6301 ccgtacttgc aattaacatc aaaaaaatac aaataaagat gccaatcagt acagactgtt
     6361 tcgctattct catcgtatct cttgaaatca ctactgcttt tgctacacgc aagagatcat
     6421 ctttcaagat gaccgcatct gcactttcac tagcagctgt agaaccatga gcccccattg
     6481 caataccgat atctgcagca gcaagtgctg gtgcgtcatt cacgccgtct cctaccatcg
     6541 caacaggtct ttgatcttta gggatacttt ctaaaatggt cagtttatct tgaggcaagc
     6601 tacgggcatg tacagaatct aattggactt tttctgcaat cgtttgagca atggcagatc
     6661 catccccggt gatcatcatc aaatttttca catcaagttt tcttagctcc ttgattgtct
     6721 ttgctgcttc tgggcgaatc tgatccgaaa ataggatcgt tcctgcaaaa gatcgatcaa
     6781 ttgttacata gattgctgta ttggacgttt ctatttcttc agctgaaaca aaagaggcac
     6841 gtccaatctt tacttcatga ttattgacta ctgcttggat tccttgaccg gtcacttctt
     6901 tcagttgact aacaggatac agttggctgt ttttcacgtt gttcactaac gaacgagcta
     6961 agatatggct agattcctgt tctgcactag ctgcatacag aagtagctct tcttttttta
     7021 ttccattgac tggctgaatc gcctctactt ccaatatccc tttggtaagc gttcctgttt
     7081 tatcaaaagc aatcgttttt gtacgtgcga gcttttcaat cgttgttcca gtttttacaa
     7141 cgatcccgtt tttacttgaa cggctcattc ctgcaactaa agcaatgggc gcagctagaa
     7201 tcagtggaca aggtgatgcc actaccagta cctcagcaaa tcgtaaaggg tcttttgaga
     7261 accaccaaga aataccaccg atcaaataag caatcaacgt gaaagggact gcataacgat
     7321 cagctaaacg gacaaatcgg gcaggctttt cttttgattc ttcgactagt ttaataatca
     7381 tttgatactg gctgtctgcg gcacgttttt cagcgatcat ttggatcgat ccgtctccat
     7441 ttaaagaccc tgacataatc tgatctccag gtttcttggt ttccgggcgg gactcacctg
     7501 tcaaagaaga ttcatcgacc gaagattctc ctttggtcac tcgaccatct gcgggtacaa
     7561 gttcgccagg cttgactagt aactggtcat caatatttat ttcatcgatt actatatcct
     7621 gcaattttcc ttctttgaat cgatgggcaa ttcttggggt gttatctaac aaagactgca
     7681 gttctttacc cgctcgttta ttcgcgtaat cctctagact atctccgccc gtaagcatga
     7741 tcaatatcat caaactagcc cagtattctt tgacggctaa tgttgcaagg attgcggtaa
     7801 tcgctaatac atctacgcca tatcttcctg aacgtaacgt cttgatcatt tccaaaaaca
     7861 tcaagaaggc gagaatccct ccagtaaatg cgacaatcgc aaatgcaagg gccggctggt
     7921 gaaaaacaaa ttcacttaat aaagctatcc caccaataag caaagtaagt aaaaattttt
     7981 tgaaatgtgt cattgttttt tctcctcttt tatgtgactt agagaggtta gtaataaatt
     8041 tccagctgcc tctttcatct taagcatagt ccttgactag cactttttaa aacaataggc
     8101 cttaattgaa aacaactatc actatcagcg tttccaaaat tcatcagttc tacaaacaaa
     8161 aatattcagc aaggattact ttttcgattc atcagttaaa aagtaccttt tttcgaaaaa
     8221 ctatgctata cttttaattc gttatttacg gcggaaggag caaacatgcg atgaatgaga
     8281 aacaactaga acaaacgcac gtggatgaaa cgatcgaact aatccagatc gaacaaaata
     8341 tgctggatac aaaacaacaa gaattgactc aggaaatgaa tcattcgaca aaagacacag
     8401 ctaatcacaa gattcgagct ggttccaatg aagcttttta tgaatctgct gttgaatatc
     8461 gccaacatga gcaggaattg cttttgaaat accatactct tgaagcacag caaaaacgcc
     8521 tgcaaacgtt gtctgtcatg aaagatagtc cttattttgc ccgtatcgac tttaaagaag
     8581 accgtgaaac agaaacatta tatctaggta tcgcttcttt aagagatctg gcagaagaaa
     8641 caatcgttat tgactggcgc gcaccaattg ccaatcttta ttatgaaggt gagattggtc
     8701 ccgcatttta tgaaactgaa acagatagaa tagatgtcga tctgcagttg aaacgacaat
     8761 ttaaaatcca agaaggacgt attttatcta tggtagatac gtcggaagta atcaatgatg
     8821 actttttgct agagatattg gatgaatcat caagcaacca tatgaaaaac atcgtctcta
     8881 cgatacaaaa agcacaaaat gcaatcattc gggacacaac aagtaaagta atgctgattg
     8941 aaggaatcgc cggaagtgga aagacatccg ctttgcttca acgtattgct tttctgttgt
     9001 atcataatcg caagtggctc gaggctgaaa acgttcttct attttcaccc aaccatttgt
     9061 tttctgatta catctcgact gtattgcctt cattaggtga aagcggcgtg cctacacaga
     9121 cattcaaaaa ttatttggtg cagctgctgc cagagttttc tttactagat gaacagcaac
     9181 aagaaagtgg ttttttgcta ggggaaaaag atccgataca agtgatgaaa agcggattga
     9241 ccttagtcga tcagattgat cgctatatcc aaggcatcac aaactacggt cccttgttcc
     9301 gtgatatgaa aataaatggc cgtacgatcc tatcaaagga atcgattcgc caatggtata
     9361 aagaaacaaa tgaacaatta cctttacatc atagactttc tctattacaa acgaagctcc
     9421 tgaaaaaatt aggcggtctg caaaaagacg aaacacgtca gcaatgggtc aaagatctgg
     9481 cggaagaaca gctccaagaa ctatacgcaa cagatccaaa tcttgaatat acagaacaaa
     9541 aggagcgttc attacgtaaa aaactggcca accaaatcgt acgtaaaaga ttccgtcgaa
     9601 tccatcgagg gatcatgaat tatcaatttg tcaatataac gaaacaatat ctccactttc
     9661 tacaaactgt gccactttct cttctaacac gacataaaat cagcgagacc aggtggcagg
     9721 aacatttgac aactgttcgt acacacttgc gtcaaagaga attgcgtcaa gaggatgctg
     9781 tactattctt tttactgatg cgccgaacat atccagtgac ggttacacac aaagctcgct
     9841 atatctttat tgatgaaatg caggatttcg caccatcaca agtggcattg ctgcaagcct
     9901 tgttcccaaa agcaaatttg actttctgtg gagatctaaa tcaaaatgtc tttggaaatg
     9961 aaacgatcgt tggatcattg gaagaccttt tcgtggaccg tgaagtcact cgtttccaat
    10021 taacgacaag ctatcgctcc acaaaagaaa tcactgattt tgctaatcat tttattgtga
    10081 aagaacatca agtagaaaca acagcaagaa aaggagacct tcctttgctc atccaaggaa
    10141 caacagatga tatcaaattg aattggttag cagataccat tcgaacgact cagggaaaag
    10201 cccggtattg gcgtacagca atcatagcta aaacacaaga agaatgcgaa gctctttatg
    10261 ctcaactgcc agacgagttg aaacaacaag tccagctgat tttaaatgag agtgacttta
    10321 tgaagcgttc cattatttta cttccagcct ttttagcaaa aggtctggag tttgaccgag
    10381 ttttcttgtg ggatgtagat gcagaacatt tttcttctca gcaagacaaa ttgatccttt
    10441 acaccatgtg tacacgtgcg atgcatgaat tgaccctttt tacctccaat aatgaaagtc
    10501 ctttgttaaa caatatggat atttcatctt atgagaaaaa agtactgtaa gtaaaaagac
    10561 aactgctatc attaatgtta gcagttgtct ttttatttac aataataatt gcagaaaaag
    10621 taattcaatc atttaaggtc atttattcta tatataaatc caaatctgtt tcaggatatt
    10681 ttaatttgac aagcgaaata atcattttca gttcttccat gttttctgga tattctgggt
    10741 caaatacctt gctatgacgg ccaatcccgc cattgtcgat caatcggtaa attcgattcc
    10801 attcaatgaa ttggtcaatt gattggaaat tgctgattgg atagccgcca caatccaaaa
    10861 tctctgatac acgaaatgct aggtatgcac tatcgatcac tttatttttt ttcgtgtcta
    10921 tcttctcatt tctttcgata agaatttttt caggacgatg tttcaagctc cactctaata
    10981 gtagaaagaa agcctccatc cgatactctt cttcaaataa ccgaaaggct gaatcagaac
    11041 gacgaaaaag cagcggaatc agataatttt gtctataaat cagcattggt gcgcggtcca
    11101 ccatacactc taaataacgg ttcagatacc ctgtaccgac atagtttcct aatcgatagc
    11161 cttcaacgcc gaatcttgcg tatttttgcg ctaattttga acaatcagtt acgttcacag
    11221 ctaactcttc tactttgcgg taaccgctta agatacgttc aaaaggttct aaagtgattt
    11281 ttgcttccat attcttcccc gtccatcttc cacatacttc atatcatttc acatgatact
    11341 tatgctctca tcataccaca ggttgaatta gaaaagaaaa taaatcacac aaaaaagcaa
    11401 gacaatctgt tagtgagatt gtcttgcttt tcgaaaaaga ctgaatactt ttcgttaaaa
    11461 ctggttgctt agtcttctaa tgccacatta tggaacacat gctgtacatc ttctagatct
    11521 tccagtgcat caatcatttt ttcaaatgtt tcttgatctt ctggagatag tgttacctcg
    11581 ttttgaggga tcatttggat ctcagcgatt gaaaaatcag tgattccttt ttcttttaat
    11641 gcttcttgta tactatggaa atccgctact tcaccgtaaa cgatgatttg tccttcttct
    11701 tccattacat cgcgaacatc gatgtctttt tccattaggt attcaaggat ctcgtcagcg
    11761 tcttctcctg caaaagcaaa gattgctgta ttgtcaaaca tgtaagaaac cgctccggaa
    11821 acacccatgt tcccgccatt tttcccaaat gctgcccgta cgtctgctgc tgttcgattc
    11881 acattgttcg tcaatgtatc aacaatcacc attgagccgc ttggtccaaa tccttcatag
    11941 cgcaattcag agtatgtttc atctcctgca ccttttgctt tttcgattgc tcggtcaata
    12001 atatgttttg gtacattata agttttagcg cgatcaatga cgaaacgtag tttttggttt
    12061 gcatgcggat caggatcacc tgattttgct gccgcgtaga tttcaatccc aaattttgca
    12121 taaatccggc tattattagc atctttagca gttttctttg ctacgatatt tgcccattta
    12181 cgtcccatat tttcacttcg ctttctgatt tgatagtttc ataacgcaaa aacgtcctgt
    12241 tccattatac ttgtgaatca cgattctgtg aagctttttt tctttcttcc ttcattcttc
    12301 tcatttttag tcaattatct atactcggat tgggatttgc ccgaaattct gttccggaat
    12361 attgcctccc aattgataga tttgatcact tctaactaac agttccgctt cttgtgcctc
    12421 tttttttccg attcgggaat aaatagaaat ctcttttttt tcttttaaga atcttcttcc
    12481 agcatcggta aatccaagta gtcgaagata atttttattt tgttggacag gaatctcttg
    12541 ctttttgata ttcagcaaga cataacaaga taatcgttgg atccgtgtcc atgtatatct
    12601 ttttgttttt acctttgaca caaaatcctc aaaactatca gcagttgcag ctgctgtttt
    12661 catgcgcgat tctattcctt cggtcatctg atagatatct gtcagttcca gcaaagtaga
    12721 agataacaac cgataacgca aatacggcca ataagattcc caagtctgca gcgaacaagt
    12781 tgaaagatct tcttctgtct gaggcggcac aagtccagct attctttttc cttcttctaa
    12841 cgcatggcga atggctgttg cactggctat cctctgatct gtgatgattt tttcatgata
    12901 gcctgcactt ttacgtcgga tcggatgtaa ttccataggg tggacatact tggcattttc
    12961 ctttgcataa cttaatccca agatatgatt tggcgaagaa aaatcaagcg taatatcggg
    13021 atacagactg cgaaaaacct cagtcatttt ttgcggataa ctatacgttt gatcagacag
    13081 ttcttgaaat gcctcttcta tcctatcttg attctcttgg acaaagcgtc cgaaactgct
    13141 gtaatcaaac gaagtctctt cttctgttcc aaaacacaaa ctgtcacagt ccagtgtttg
    13201 caagattttt actgcacctt tagcaaaata gtcagctgac tgaaccgccc attcgacggg
    13261 aagctccact actaaatcca caccattttg taaagcttca ttcgcgcgat gccatttatc
    13321 gatgatagcc ggttcgcctc tttgcaaaaa attcccgctc attacagcaa tgacgacctc
    13381 tgctcctgtt atttttcgtg ccatttccac atgatagcga tgtccattgt gaaaaggatt
    13441 gtactctacg ataatcccgc agcttttcat gcgcatcctc cttcatagtt atcgataaaa
    13501 aagaaataga gacaagtaaa aaaaggcaaa aatcggaaaa aatacccgaa ctatataaac
    13561 tattctcgca aacacaatac ttctgcgacg aaaagctgca ctgcaagagc aatgcctata
    13621 tcgttcggat atataattta tgttgaagat ttattctttt cttgttaact cgagcaggca
    13681 aaaccgctag tctttgtatg ctacaaagaa ccagcgcttt gatttctctg atgctgcttc
    13741 gtctgtaaaa tcagaaaatg cttcgacttt cgaaaagccg ctgttttcca gcattcttaa
    13801 ataactttcc aatggatagg tacgctcttg atgtagttca tcttcacgaa taaatcgacc
    13861 agacccttct tgttcttcaa cgaaaaaggt aagaaaatgt tcgatgctgt gtttctcgct
    13921 tcctggataa ctatcccaca aaaaagcaaa attatcccct tgataatgat agctatattc
    13981 tggaaaaacc tcatctactt gataggtgga gtgtacgtca aataaaaatc ggccattttc
    14041 ttctaacgct tgatagactt catcaaacac ttgctgtacc tcttgtctat ttttcatata
    14101 gcacagcgaa tcagaaaaac aggtaattgc ctgatattgt ccgatttctg ataaatcgag
    14161 catattgcct tccacaaatt ggatcgatgc gtcttcttca tatgctcgct ggctggcaat
    14221 catcaacatc tcttctgaaa ggtctaaccc tgtcacttta tatccatctt ttgcaaaggc
    14281 aaccgctaat gctccagtac cgcatgccag ttccaaaata ttttttgtgt cttcttgtaa
    14341 atgacgtttc gaaaaagcta accattgctg ataaagtgtt tcgtccatca cttcatcgta
    14401 aatgaaagca aatgtttcat aagccatatg ttaatccaac cattcactaa gatcgactag
    14461 cggagcatct gaccatagtt tttccagatt atagaaattt cgttctggcg catggaaaac
    14521 atgtacgatc acatctccaa gatcgatcaa tacccatttt ccgccttctt ttccttcaat
    14581 acgttttact tcatatttgt tttcttcttc tttatcaatg atttcttctg taattgcgtt
    14641 gatttgacgt tcgctatttg ctgaacagat catgaaataa tctgccaaca aggaaacatt
    14701 tcgaacgtct aaagcgataa tgtcttctgc ccgttttgaa tctgctgctt caatcgcaat
    14761 ttttaattgt tctttactat ctatgatgat ttcctcctaa tatgagcagc ttattttttt
    14821 gctacccagt aattatatgt ttcgattgtt tttggataaa tctgttgttc ttgcgcaagc
    14881 aaatgggcca atgtatgttt tgtttcaaat gctacagctt cgtctagatc agcccatgca
    14941 atggctcgtg catcttgtac cccaggaaaa tctcgacctg gttcaatata gtctgctaca
    15001 taaatgattt tgtcaaggag actcatctta gcagccccag tcgtatgcac ccggattgca
    15061 tgaagaatct ctgcatcggt gattcctaat tcccgctcta caaacgaagc gccaacaaga
    15121 ccatgccaga ttgcattatt ataattcaat aactccggat caaaaccgtc tcttacgatt
    15181 accattttga actcctcatc tggtcgttct tttgcataat catgtgtcaa tgcagcaata
    15241 ctagcttttt caggagaagc accgtatttt ttggcaagag ccacggctgt ttcttctact
    15301 ccaagcacat gcttgaagcg ttgttcgctc attctcatct gtattttttg catcaggttt
    15361 tctctagaat aagcagtata ttcattacta tagtccatat tcatacaacc cttcattttg
    15421 aatataatca attactttat ctggaacaag gtagcggata gaacagcctt ctttgatctt
    15481 ttgacgtatt ttcgtggaac tgatgtcgat ctcaggtaca tctacccaaa ttacaggata
    15541 tggagtatcc gttgtgtatc ctggtcgacg tatacccaca aagttgacca tagaagtcag
    15601 ctcatcgatt ttataccatt ttggcaaata ttctaccata tccccaccga taataaagta
    15661 ataatctgta tccggattgt tttgcgtcaa ttccttcata gtatcatagg tgtaactttt
    15721 cccaccacga gctaattcaa tcgtttcaat ctgcaaaaaa ggattgtctt ccaccgctaa
    15781 ttccaacatg ttgagtcgat gttttgcatc aatcgtctgt ttctcatcaa catgaggtgg
    15841 ctgataagaa ggcatcaaaa atacgcggtc aagacctaaa ttccggccag cttgttcagc
    15901 catcactaaa tgtgcaaggt gaacgggatt gaatgttccg cccaagatcc ctacttgctt
    15961 tttcttctct aagaattgag gcatttcttc aggaaataat tgtgaacgaa caaatgtctt
    16021 agcttgcgta ttcatcatgg tcactcctta tattgctttt acttcttttg atagcctttg
    16081 atacttttct tttgtggaag gtttgtataa tacaataaca cgtccaatga tttggacgat
    16141 ttcgcaatct atttcttttt ctaatacttg agctgcttct tctgcaatct catctgtatt
    16201 ttgaagtaac gatactttga tcagttctct tttttctaaa gcttcttcaa tttgaacgat
    16261 cattgctgaa ttgatcccac cttttccgat ttgaaaaatc ggctgaagat gatgcgcttt
    16321 gctacgtaaa aaacgctttt gttttcctct taaactcata attttccttc ttccttaaat
    16381 caatgctttg cgtttcaata catctacacc ctttggcgcc cagcccgcaa ttactactgg
    16441 cgctgttaca gtgatccagc ctagaccggc aaaaacgatg tctgtttttt ctttcacaga
    16501 aaactcaaaa cgaacaagct ccggaaatgc ctcgacttca tcaggacgag gaggctgtaa
    16561 taatccacct acatgttttt gataaaattc gtctgctttt tccagtttcg ttcgatgaat
    16621 atttacatca tttgacacat aagcaataaa tgaagcacga ttgccgctga taaaatcaaa
    16681 tcttgcaagt ccgcccaaga aaagtgtttg cccttcattc agctgataaa ctttaggttt
    16741 gatttctttt aacggtgcaa tgatccgcaa atctttttta cctaagtagt gcgccatttg
    16801 atggcgatgg ataattcccg gtgtatcaat caaaaaatgc ccgtcatcta aaggaatctc
    16861 gattttatcc aaggtcgttc ctggaaactg cgaagttgtg attacatctt gtactcccgc
    16921 tgtatttttg atgatttgat tgataagcgt cgattttccg acatttgtta ctccgacgat
    16981 atagacatcc cgtccatcgc ggtattcttc gattttttct aatagttccg tcatctcatg
    17041 agatttctta gcactagtta ataatacatc tactggacga attcctgctt cgtaagcacg
    17101 ttccttcatc cattgtgtta atttagtttt tttcaatgat ttaggtaata tatccacttt
    17161 gttcccaact aaaagtactg gattgtcacc gacaaaacgg tgtagtcctg ggattagtga
    17221 accattgaag tcaaaaatat ccaccacatt gacgatcaat gcatcttttt gccctaattc
    17281 attcagtaag cgcaaaaagt cgtcatccgt caatgagaca tcttgggtct cattataatg
    17341 gcgtaatctg aaacaacgct gacaatagac ttccccggaa gctaaacctt tttccaaagc
    17401 cgtttgcggc gtgtatccta attcaccggg tttgtttgtt tgtataacgg caccacagcc
    17461 gatacattgt aattcttctg tcattcgatt ccacctcgcc agcccatatc agggtgtttt
    17521 gctaatagat aggccataat tcttttttcc caaaaacgat taaattgtgt cttccaacta
    17581 tctgttgcga taatgggttt tacaaggatg ctacgtatcc ctgcacgatt ggctccacgt
    17641 atatcagtca taatctgatc gcctaccatt actatctcat catctgctaa atccaattgt
    17701 ttctttgcta tgttgatccc tcttgctaaa ggtttcattg ctcgtgcaac atacaaaaga
    17761 tcaaattttt caatcgctcg cgcgacacgt tttgaattat tgtttgaaac aacaacaaca
    17821 gggattcctg catttttcat ttctaaaatc caagtaagca actcttctgt tccatctgga
    17881 ttattccatg caatcaacgt attgtctaaa tcggtcaata ctgctttgat gcctagattc
    17941 tttaattggg caggtgtaat ctgatagatg gcttctacca tccatgttgg tttgtaattt
    18001 gaaaacatgc tgtctcctca tctgcaaaaa atgaaggagc acataaagta ctcctcaacc
    18061 ccgtattata ctgcatatca gcaaaaaaaa ctacctctat actcgttcgt ctttcagaaa
    18121 aagcatttct ttacaaaatg accaaaaata aagattgatc acagaaaaat ttagaaacaa
    18181 aaaacaacta atattggcgg aacctcttgt atcgtttttc cagtaattta tgctgatcta
    18241 atcgaacaag ttccgtcaat ctttcaatca acgctttttt cataatgtgt gcgactttat
    18301 atcgtggcaa ctgctcgccg ttgaacgttt caggaataac tcgatcaacg attcctaact
    18361 cgcgtagttc tggcgcagta attttcatca actcagctgc ttctgcggcg cgactaccgt
    18421 ctttccacaa aatcgacgca aatccttctg gagaaagcac agcataaatc gtttcttcca
    18481 gcatccagac ttcatccgct aaacctagag caagggcacc gccacttcca ccttcaccaa
    18541 tgatgatggc gatgatcggt acctttaaat cagacatttc gagcagattt ctggcaatag
    18601 cctctccttc gccgcgctct tctgctccta caccgcaata tgcacctgct gtattgatca
    18661 aggtaatcac cggtctattg aacttttccg cttgtttcat cagtcgtaaa gcttttcgat
    18721 agccttcagg atggggagaa ccaaaatttc tgcggatatt ttcctgcaga tcccgtcctt
    18781 tttgaatacc gatcactgtt accggtttgc catctaatcg agcgattcca ccaacaatcg
    18841 cttcgtcatc tgcaaataaa cgatcaccat ggcattcctc gaaagaatcg aagatctctt
    18901 caaaaaaatc caagcttgtc catcgttctt tagctcttgc taactgaacg acatcatgtg
    18961 ctgtcttatc cacgatctat ccatcctttc tgtgtatgca attcaagaag cgtatggatt
    19021 ttctgtttca attccatgcg gggaacaatc tgatcgacaa aaccatgaga taataagaat
    19081 tcagcctttt ggaaatcttc tggaagttcc tgcttgatcg tctgttcgat gacgcgtctt
    19141 ccagcaaaac cgatcaagct ttggggttct gctagaataa tatcgccttc cattgcaaaa
    19201 ctggcagtta ctcctccggt cgtcgggtcc gttaaaacag ttagataaaa aagaccttca
    19261 ttgctatgcc gtttgacagc agcagagatt tttgccatct gcattagaga aaagattcct
    19321 tcttgcatcc gtgcgccacc tgaagctgtg aacaagacga ctggaagact ttcctttgtt
    19381 gctcgttcga ataatctggt gatcttttct ccgacaatcg ttcccatact tcccatgata
    19441 aaattaggat ccatcactcc aataatgaag ggaatcccct gaatggttgc tttaccagtg
    19501 aggactgctt catgaagtcc tgttttatct tgcatttttt taattttttc cgtatattcg
    19561 ggaaatgcta gcggatcttt ggttacaaga tccgtatccc attcttcaaa acttttttca
    19621 tcaataatca aagctagacg ctgccatgca ccgattcgaa aagcgtatcc gcaatgaggg
    19681 catacttttt cttcaccgat gtctttcgta taaaggatat gtttgcaatt tggacacttt
    19741 gcccacatgt tatcaggaac agatggcgag ttagcaggtt tgctctctct attaggattg
    19801 atccgaatat atttcttttt cttaaacaga gccatctatg cgcctcctat ctccgtttct
    19861 ggtgtccaat tcggtaaaaa ttcttcttgt aaaaatgctg tgctgtaatc acctgctatg
    19921 actgcaggat gactaatcaa atccatctga aattctgcgt tcgtgatgat tccttctgtg
    19981 ataaattcac ttaaggctcg ctgcatcttc attaatgctt caaaacgcgt atttccatgg
    20041 acgattattt ttgcaatcat tgaatcataa tatggcggga tcgtatatcc cgggtaaact
    20101 gcactgtcta ctcgcagtcc catcccacct gctggaagca gtaagttttg gatcttccct
    20161 ggagaaggag caaaatggaa agcaggattt tctgcattaa tccggcattc gattgcgtgt
    20221 ccttggaata ctacttcttc ttgacacaca ttcaaaggct caccggctgc tatctccacc
    20281 tgttttttta ctaaatcgat tcctgtgacc atttctgtta ctggatgttc cacttggatt
    20341 cgagtattca tttccatgaa ataaaaatcg ccttcttcat ccatcagaaa ctcgatcgtt
    20401 ccggcatttt cataattgac tgctttagct gctcgaacag cagcgtctcc tagtgcttct
    20461 ctttttgttt gtgagatcac tacagaagga gattcttcca gtactttttg attgttgcgt
    20521 tgtaaagaac aatctcgctc gcctaaatga atgacatgac caaatcgatc acctaagatc
    20581 tgaacttcta tatggcgagc aggataaatg attttttcca aatacatatc atcatttcca
    20641 aatgccgctg ctgcttcttg ctgagctgaa gaaaaatgct gtgggagctc ttcttttgat
    20701 tgaactttcc gaatgccttt cccgccacca cctgcagctg ctttcagcat cactggataa
    20761 ccaattctgt ctgctatttc caatgcttct tctactgtag ataatacacc agtacttcct
    20821 ggaatgactg ggacatttgc ttcttgcatc aattgacgcg cattgatctt atttcccatt
    20881 gcatcgatcg ttgcactttt aggaccaata aatgtgatat tgcactcttc acacatggag
    20941 gcaaatcggc tattttcaga taaaaaacca aatcctggat gaattgcttc ggcttttgtc
    21001 acgattgcag cgctcagtac ttcctgaaca ttcagatatg aatcaacggc ttttgccggg
    21061 ccaatgcaga ttgcttcatc tgctaactgt gtatgaagtg cttcggcatc tgcttctgaa
    21121 tatatcgcta cggtttggat ccctagttcg cggcatgcac gaatgatacg tacagcgatt
    21181 tcaccgcggt tagctatcaa tactttagaa aacatatttc acctatccaa tcataaaggt
    21241 taattccgct tcggctactt ttttaccgtc tactttagcg attcctttgc ctattccggc
    21301 tgaagctttc actttcaata tctcaacttc aaggtataag gtatctcccg gtgtaacttt
    21361 cttacggaat tttgctttgt ccaatccgcc gaaataagcc gtctttccct tgaattgttc
    21421 aagagaaagt aatgcaactg ctcctgcttg agccattgct tcaacaatca atacccctgg
    21481 cataacaggt tcttctggaa aatgtccttg aaaaaagggc tcattgatcg ttacattttt
    21541 cttagcaacg atccgttctc cttcaaccat ttcttccact cgatcaatca aaagcattgg
    21601 ataacgatgt ggaatgattt cttttatttc ttgtatgttc attgttttcc ctctttcctg
    21661 ctttgcttat ttttgctgaa tcctaaagag tggctgtcca tattcgacaa ctgactcgtt
    21721 ttctacaagg atttctgtga tcactccgtc ggcctcacta gttatctcat tcatcagttt
    21781 catcgcttca ataatgcaga taacttctcc tttggcaact tgatcaccta cttttttgaa
    21841 agctggtttg tcgggcgctg gttgcagata aacgattccc acgattggcg aaacaacctc
    21901 gattccatca aatactgccg attctttttc tttcattatt tctggagcag ttgttgcttg
    21961 ttcaggtatg acattgactg gctccgaaac tggcaacgtt tcgtttgttt gaaccatatt
    22021 catgcctcga cttgttttat ttttattcat atacaattca aattgacctt cacgcaaatc
    22081 gaattccgtt agcgaggatt gatcaaattg actgactaat tctctgattt cattgatatc
    22141 caaaattatt cctcccagcg tttcatgcac agaaccgcat tatgtccgcc aaaccctaat
    22201 gaattactca ttgcataagt aaaacttgca ggtttgcttt cgtttttgac aactgtcaag
    22261 tcaatctcag gatcttgttt ttctacattg atcgtaggtg ggataaattg atgttctaat
    22321 gccagcaaag ttgccaaggc ttcgatcccg ccggctgctc ccaataaatg tccagtcatc
    22381 gatttcgtgc tgctgacgta agtatctctg aaattttcac ctaatgcgat ttggattgct
    22441 tttgcttctg cctggtcatt ggctggtgta cttgttccgt gagcattgat atatccgact
    22501 tgttccggct gtacaccagc ttcttccatc gcaagcttca ttgctttaga tgcaccagaa
    22561 ccatctggag taggagctgt catatggtaa gcgtcacagt ttgcaccgta tccaacgatt
    22621 tctccataga ttttggcacc gcgagcttgt gcatgttcta aagattcaag aactagaacg
    22681 cctgctcctt cacccatcac aaaaccattc cgattttcgt caaacggaat cgaaccacga
    22741 ttaggatcag ttgattctga gagtgctgtt aaagctgcaa atccagcaat ccccatctca
    22801 caaatcgttg cttctgttcc tccagcaaga atgacatcag aatagccatg tttgatgtta
    22861 cggaatgctt ccccaattga attcgttccg ctagcacaag ctgttacgat agctgtacaa
    22921 ataccttttg cacctacacg caaagcaata tttccagctg ccatgttggc aatcgccatt
    22981 ggtacgaaca ttggagaaac tcgttttgca cctttttcat gtagacgaat aacttggttt
    23041 tcgattgttg gaagaccacc gatcccagat ccgatgatga cgccaaaccg gtcttgattc
    23101 attttttctt tatctaaacc gctcatctcc attgcttcta aagcagcgta gattccatag
    23161 atcgaaaaca tatccattcg tttgctatct tttttaataa aatatttatc gtaagggaaa
    23221 tctttgactt cacccgctaa ggtaatccct gtttctgaag catcaaattt agtgatcggt
    23281 gcgatgccat tcgtcccctc ttttaagcta ttcaaaaagc tgtctgcgtc atttccaata
    23341 ggtgaagtga ctccatagcc agtaattacc actcgattca tttgtttgct ctccttttct
    23401 tatccgtgca tgaccaatcc gccatcgaca ttgatgactt gtccggtgat atatggattt
    23461 tgtgctaaga aaactgctgt ttgtgcaata tcttctactt gtccgaaacg ctgcatcgga
    23521 atttgctttt ccgcttgttc cttgactttg tctgctaaaa cttccgtcat atcagttgtg
    23581 atgaatcctg gcgcaatggc attacatgta atgcctctag ttgcagcttc tcgtgccaca
    23641 gattttgtta atcctactac gccagcttta ctagctgcat aatttgcttg accaatattt
    23701 ccaatcaacc cagatacact agagagatta atgatggccc cttctcgctg cttcatcatt
    23761 tttttcaata cgtgctgcgt catattgaag gttccaatca aattgatatc cagacatttt
    23821 ttgaaatctt ctgcatccat tcgcatcaca agtttgtcat ttgtgattcc ggcattgttt
    23881 actaacacat ggatcgatcc aagcttttct tctgcttctt tgatcatttg tcccgctttc
    23941 tcataatcag agatgtcacc ggaaactcct acgcatttta caccgaatgc ttcgatttct
    24001 tctatctttt cttttggaat ctctccgcga ccattcaaaa tgatatttgc tccagctttt
    24061 gcaaaagcta aggccatcgc tttgccgatt cctcttgtac tacctgtgat aaatacattt
    24121 tttcctttta catccataac gttcctcctt atagtattgc tattgtttca tcaaatgtct
    24181 gcttattctc aacacgcaga actggtattg ttttatcgat ttttttcata aatccgctta
    24241 atacttttcc ggggccgact tcgatgactt gttcgatgcc gattgttttt aacttatgga
    24301 tactctcata gaaacgaaca ggttgcatga cttgctgttc aagtagtccc gcgattgttt
    24361 ctttcttcat tatttccgtt gttgtgttgc ttatgatagg aaaagaaggt tcagagaatt
    24421 gaatctgact taggtccttc gccagttttt ttgctgccgg ttctaaaata gctgtatgaa
    24481 aaggcccgct gacatttaga gggatcattc ttttgaaccc tttttctttt aatagtaaaa
    24541 cagcttcgtc tactgctttt tcttcgccac caatcacgat ctgctgaggt gtattataat
    24601 ttgcaggaga tacgatgccg tacttgctag cttcatgaca gctttcctcg atcgtttcaa
    24661 tcggcgcatt catcactgca accattttcc cgcttccagc tggggcagct tctgtcatat
    24721 aagcgcctct ttttgctact aacgcaactg cttcagtgaa ggatagcgca ttactagcta
    24781 ctaatgccga atattctcct aaactcagtc ctaaagctgc atctgggatg attccatgct
    24841 ccttcaataa gcgataatac gcgatgctga ctgttagaat agctggctgt gtatattgcg
    24901 tctgatccaa acgttcattt tctgtaaagc aaagttcagc catatcgtag ccgagaatct
    24961 cacttgcttc atcaaatgtc tgctttacaa cggcttcttc atataaatct tttcccatac
    25021 cttgatattg tgcaccttgg ccactaaata agaatgctgt tttcatgttt ttctccaata
    25081 tatccagaat atatgtttga ttcttcctat tcaaaaaggc cgagacattc ctatttcagg
    25141 aaatgtccca gcccccaacc taattttaat gattatgcag tttgtttttc tacgtaagtc
    25201 actaaatctt gaaccgtttt gattccgtct tctgtttcga ttttcacgtc aaattcatct
    25261 tcaatttcat tgatgatttg gaataaatcc aagctgtcag cttctaagtc ttcttggatg
    25321 tcagtagtca atttgatttc ttcagtttct tttcctaatt cttctgcgat gatttcttga
    25381 attttttcga ataccataat aatatattcc tccgatattg tttgcttttt atttttataa
    25441 tttaacagtc tacaactcca tgagaatact tccccatgtt aaacctccgc catagcctgt
    25501 aaatattact ttctgctgtt ttcctaaggt gatctttcca ctagaaactg cttcatccaa
    25561 taagataggg atgcttgcag cagatgtatt cccatattta tccatattgg tcaggaactt
    25621 ttcttgcggc atctttactt ttcgggcaat tttctcaata attctgaggt ttgcctgatg
    25681 caaaagcaga taatcaactg gtttgtcttt catgacttct tggatattgt ttgcaacgtc
    25741 tcgtacggca aaatcaaaaa tatctctgcc agtcatttgc aaataatacg aaccttctga
    25801 atcttctgaa tagaacggat ttttattttg ctggtagcca gcggtcaatg agctacttct
    25861 ggtaccgtca gctgctaatt tttctttcag caattttttc tgtggattcg cttctaagag
    25921 aatcccacct gctccatcgc caaacaacac agcagtcgta cgatcagacc aatcgattag
    25981 cttagatagt gtttcaccac caatcaccag tcccttagtt gagccgcagc ggatcatttt
    26041 ttcagccatg cttaacgcat aaacaaatcc tgagcacgca gcactgatat caaaagcgat
    26101 agcatgagtt gctcccaatt tcccttgtac ttgtgctgct acagatggtg tcgtgtaatc
    26161 gggcgacatt gttgctacta aaataaaatc caaatcttta gggtttagat ttttctgttt
    26221 tatcaatttt tccgccacta aaatgcataa atcagaagtc tcctgatttg ttacacatct
    26281 tcgttcacga atacccgtcc ttgacgaaat ccattcatca gaggtatcca tcatcttgga
    26341 aagatcatta ttagtaataa tcttttcagg aaggacgctg gctgttgcag taatcattcc
    26401 aaattgttcc attaaatatc ctcacttata gtcttgcaag aagtcgtgca agtttttcag
    26461 tgcatccagc aaggcatgct gttcctccgt agccattccg tctaagatgt tcttgaccat
    26521 ttcacgatga aaatgctgat ggacccgaaa tagtaacttt ccttttttcg ttagtcccaa
    26581 ctttacaacg cggcggtcat cttcactgcg gatacgttcg acatagcctt tttttactaa
    26641 cttgttaata gcagtggtca aggtcccaac agtaattgat agttctttgg ctacttctga
    26701 agttgttttt ttcttgtaca tcccgattgc ctcgatcgtg tgcatctctg tgattgacag
    26761 atctttgaat tgagattttt tcagctcaga ctcttcgatt gtcaaaatat cattgaagac
    26821 actaacaaga taatcattta ctgtttttaa atctggttcc atgttccacc gtccactaat
    26881 tagtttgatt atcaaatctt ttgatgttca aactatatct taactttttt caaaatgcaa
    26941 ccttaaaaga tcattttttt actatatgag ctttttttaa gattttactc atttaaaaca
    27001 actgataaat cagcatttat aatttctttt attagaaaaa tcatctatct cacatatttt
    27061 gattatcaaa gtattttctg tgaacagaac tatagaattc cctaaaactt gtccattatt
    27121 tcaaaatttg ttatagtctt tttattcaaa gcgtaaaagg agatcctatg ttaaaagaaa
    27181 aaatgaaaac tctccccatg ctgccgggtg tctatcttat gaaagaccga gatggtaagg
    27241 tcatctatgt tggtaaagca aaacggctca aaaatagagt aagcagctat tttcatcaga
    27301 ataaacagca ttcaaaaaaa gtattacgta tgattcatca tataacagat tttgatttcg
    27361 tcgtagtaga cacggaatta gatgctttat tgctcgagtg tcaattgatc caacattacc
    27421 gtccttttta taaccgacaa atgaattatt tcagtaatta taattatgta catattacca
    27481 ataagggatt tgtattaaca gatactccta cggctcgaac atacgggcct tttcgtctct
    27541 ataaaaaaat gccgtctatt ttgcgtataa tggaagaaac ttatcaaatg ccttggttgt
    27601 ctgaaattag tttgttagct ttgcgagtcc agcttcctga cctacaggaa atgacttttg
    27661 aacagaaaaa aaaggaactc caagggctgt ttcaaggccg aaataaaaag ctactgactt
    27721 acttgaaaaa aagacaacaa catttcatct atcagttgaa tttcgaaaaa gccggtatgc
    27781 ttcaaaaaga tatcgaatta gttacttatt ttattagacg gatccaggaa caaaagcagt
    27841 ttttaagaac accatcgctc accttcagca tgccattagc agcagatgag agtcagaaaa
    27901 agcactacct cgtttgttat ggtcaacttg cagaaacaat gattacctct ggtgacgttt
    27961 ctcctgactt ctattatgaa aagaaagaag ctcatttatc tttgaaacgt caattgtcaa
    28021 aagaagaaat cgatcctgta caaatcttga tcagttaccg caaaaaatta gaaaaagaac
    28081 agtttgaaat tgaactgtta aacaaaaaag aagctgaaaa gcaactaaat tagttgcttc
    28141 tcggcttctt ttaggcatct tcaacttcaa atgtcaatta tcctaaaatt tattggatta
    28201 agtcatagat ttccatcgct acgatatcga tattatcaaa ttcgtattgc tgatgagtat
    28261 ctgtttcagt taattcaaat gtatcggtcg ctttatcata agttactgta cacttctcta
    28321 cgccttcttt ttcaaaacgg cgaacttgca gttcattatc tgctgactcg accatagcct
    28381 ccagtcgttt tatgattgcg actaattgtg aatgtgtcat cggaggtcct ccttttctta
    28441 tttctgttat attgtatcaa aagcatagcc tacttgcatt gattttctct aaaaaaactc
    28501 gttttttatg attttttttc tggtattttt ccttcaggcc accaaagttt gatcaaagct
    28561 tgggttccgt cattctcaaa acctttatct gccaactctt catatagttt caatgcttgg
    28621 gtagttgctg gcaatacaag atccattttt tctgcttctt ctaatgcaat ctttaaatct
    28681 ttgataaaat gtttgacaaa aaaaccaggt gtgtaatctt cttttaaaat acgaggagaa
    28741 taattgctta aagaccagtt agctgcactt ccacctgaaa gcgtctcaat cactttcttt
    28801 aaatcaagtc cgtttttttg tgcatagaca agcatttccg tcattcctgt catcgtacct
    28861 gcaatcatga tctgattagc catttttgta tgctgacctt tcccagcaga accatgcaat
    28921 gtaaatgtcg taccaaattc tttgaataaa ggcagtactt gatcataaac ggcttcttct
    28981 ccaccgacca tgatcgtcag tgtaccattc tttgctccta agtcaccacc ggataccggt
    29041 gcatctaacg catctgcgcc tttttctttt gctgtttttg caattttttc tgccaggctt
    29101 ggtgtacttg tagtcaaatc aactaaaata tgtcctgaga tatctgcaga aaaaatcccc
    29161 gactgtccat agtagatttc ttctacatct ttggggtaac ctaccattgt aaagagaata
    29221 ttactttgtt ctgctaccgc ttttggtgta tctgcccaga tagctccttc tgttactaaa
    29281 ggatcagctt ttgcttttgt ccgattatag acagctactt cgtgtcctgc ttctagtaga
    29341 tggcgtgcga cagcacttcc catgacgcct gttccgataa aaccaagttt cattttttcg
    29401 acctcctaaa aatcaaaaat ccttgcttct atgctagtat acgctagaaa caaggatttt
    29461 ttcataaaaa atgtttgaat tttatctttt aaatgaattt aattttattt tgattcgttc
    29521 aatcgagtct tcttcttctt ttcttcgcat ctcttcttca tgataaacaa ccatgtcttg
    29581 ataaaattcg atcatagctt cgccgaaatg tgtagatgaa atatcataaa gtttagcttc
    29641 taaaactttt ggatctttag gaacttcact ggaaatataa tcaataagtg ctggtgcaaa
    29701 gtcttcgtcg gtttcaaaag ttttccctaa tgaaggatga tcgaacaatc ggttcaaata
    29761 agcatttcct tccacgacac aaggtgttcc ggctgccatc gcttctgtat aagtaagccc
    29821 ttgtgtttct gaagtagaag cactgacaaa ataatctgcc gctttataat aaagtgctac
    29881 atcattgttg tccacttctc ctgtgaactg cacaaattct tctaactgca gttctgagat
    29941 caattcctct aactcttcta cataaggtcc ttttcctacg ataactaatc tggcgttagg
    30001 ataagcggag atgacctgag gaaacccatt aatcaaggct tggatatttt tctcataaga
    30061 aatcctgctt aaagaaagaa tcatcaaatg gttttcctga agacctagtg actcccttaa
    30121 tttgctgata tcctgctgag tgatatcaga acgtttgaat ttttcaatgt cgataccagt
    30181 aggaatcacg cgaagcggtg ctattacacc atagctgcgt aatgtatcaa taacacgttc
    30241 acttggacaa actacacctg tcgtatgatt tgcaaataat ctagacaagt attttacatg
    30301 ggattgcctg atcacttttc ctttaccgat ataatgaagg tagtcttcat acatcgtatg
    30361 gtaagtatgg atcagaggta ttttcaactt cttagctacc atcttcccaa gtatccctgc
    30421 tccgaattct gtatgggtat gaataagatc tagttctagt tctttggcaa ccaaataagc
    30481 ataccacatg cctctaacaa caactcttcg atccttgaaa gaaataaatg gtacacttgg
    30541 cattcgaatc acatcttttt ccaacttatc cgcattagga tcggtcgttg taaaaatata
    30601 gacttcatgc ccatgtcttt ctaattcttg ttttaatgtt ttgatcgatg tagcaactcc
    30661 gctgacttgc ggaaagtagg tatcggtaaa aaagccgatt ttcatgtttt tcgcctccaa
    30721 actagtcctt gacctgattt acttttttta atttgctaga gactttttca ttcagtacac
    30781 tttcgtatac atttttaagt tcttcaccga ttttattgat acttcgctct tttgctgttt
    30841 gataaccggc ttgtgtcgta ctcggtagtt cttgattggt aatctgttgg atcagtcgga
    30901 taaattcttc gtttgtcttc cccatatagc agttcttgct atcttctaac cagccattat
    30961 acactggaat atctcgaaca agtacgtttt gtttgcttgc taaagcttct aaaacaacga
    31021 tcccttctgt ctcttcataa gaagggaaaa agaatagatc tgcacctgaa tacgcacctt
    31081 ctatgatctc tccacgaatg taaccaggaa acaggacatt ttcaggatga tcttctttta
    31141 caattttccg gatgttccga ggaatcgagt acatgggaac atgaccaaac caaataaatg
    31201 tgtattcggg catcttctta gcaatttcta cgaaatcaat gattccttta cgttcgaaaa
    31261 acaaaccgac acaaatgatt actttttgat ccggagacag tttgaaatat tctctgaact
    31321 tttgttcttt cattggatca gggtgatatt tctctaagtc gatcccattg gaaatagctt
    31381 gaatcggcac acggatacca tagctttcca acaactgttt tgaataaggt gttggcgtga
    31441 tcagatagtc cgctttttgg tacaatccta ccagatattt ttttacgata ggagaaagct
    31501 ggttcgatcc gataaaggaa tttcggaaat cttcctctgt agaatgcgca tgatagacaa
    31561 ctttttttcc ttctcttctg gctttattga ccatattatg actattgatt ccgtatgtat
    31621 tgatgtgcag gatgtcataa tcttcttttt catctagtgt ataagagata ccgacttccg
    31681 tcagagcacg tttttgatga tcaagcgcac gcccgattcc agattttgca agcatctttt
    31741 cactttcaaa atataataat accttcacct tacgtccccc ttcacttata tagtataaca
    31801 tagcctacaa actgtcactc aaacttaagc cctatttttg tctattctta ctgacaaaaa
    31861 cgttttctta aaaaagaaca aaaaaactgg cgtagctctt ttacaagcca caccagcttt
    31921 tgatacgttg tttattttac atattcatga acaagttcaa cgacttcttc catcgtatcg
    31981 cattctttca atgcacgatc agcaagttca gccattttcg ctgtgtccaa gcgtttcatt
    32041 aaactacgcg ttttaagaat agatgtcgca ctcattgaga actcatctag acccatacct
    32101 actagcaatg gaacagctgt ttgatctcca gccatttctc cacacatacc tgcccatttt
    32161 ccttcagcgt gtgctgcatc aattacattt ttgatcaaac gtaaaattga tgggttatat
    32221 ggttggtaca agtaagaaac gcgttcgttc atacggtctg ctgccattgt gtattgaatc
    32281 aaatcgttcg tacctacaga gaagaaatct acttcttttg caaacttgtc tgctaagact
    32341 gctgctgctg gaatctcgat catgatgccg acttggatcg tatcagatac ttccttgcct
    32401 tcacttatca atttttgttt ttcttcttca aagatcgctt ttgctgcgcg gaattctttg
    32461 agtgtagcta ccatagggaa catgatacgt aaattaccat gaacagatgc acgaagcaat
    32521 gcacgcattt gtgtacggaa catttcgtcg ccttgttcag ataaactgat acgcaatgca
    32581 cgatatccta agaatggatt catttcatga ggtaattgca gatatggtag ttctttatct
    32641 ccaccgatgt ccattgtacg aacaactaca ggttttcctt ccataccttc taatacagct
    32701 ttgtaagctt catattggtc atcttctgtt gggaagtctg gagaatccat atacaggaat
    32761 tcagtacggt acagaccaac tgcttctcca ccattattat ggacaccaac tagatctttt
    32821 ggtgttccga tgtttgcagc taattcaaaa tgcttgccgt cagctgtgac agtttctgca
    32881 ttttttaatt tttcccattc tgctttttgt gctgcgtaat ctgcacctgc tttttcaaat
    32941 tcagcttttt gttcatctgt aggatcgatg attacatcgc cttcgatccc gttgacagcc
    33001 aaaatatcgc cttctttgac tttagcagta atttcttttg tcccaacgat tgctggaatt
    33061 tctaaagaac gtgccatgat agcagaatgt gaagtacgtc caccaatgtc tgttacaaac
    33121 gcttttacaa aattgcgatc taattgtgct gtatcacttg gagtcaagtc atgtgcaaca
    33181 acgaccactt cttcgttgat cattgatgga tttggtaaag taacgcctaa taagtgcgct
    33241 aaaatacgtt tagcaacgtc acgaatatct gcagcacgct cttgcatata agcattatct
    33301 tccattgctt cgaacatacc gatatacata tccgttactt cttttagcgc tgattcagca
    33361 tttacgctgt tgtctttaat attttgcttg atttgaccta ccatttctgg atctgaaaga
    33421 accatcaaat gggcatcaaa tacttgcgct tctgcttcac ctaagctttg cgctgctttt
    33481 tcacgaattt gctgcaattc ttcagtagat ttagctaatg cagcatccaa acgagcttct
    33541 tcagccgcag tatcttctac tgttgcctta ctgaatgtta aatccggttg aactagcagg
    33601 taagcttttg caacggctac accgtcacta gcggcaatcc cttttagcat ttcaaccatt
    33661 attcagataa gccttctttc ttcattgttt caacgattgc tgccattgca tcagcttcgt
    33721 cagcaccttc tgcagtaata gtaacatcag aaccttgacc tacacctaaa gacataacgc
    33781 ccatgattga tttcaagttt actgatttac ctttatactc taagtttaca tcagagttaa
    33841 atttgcttgc tgtttgtact aatagtgtag ctggacgagc gtggatccca gtttctgcta
    33901 ctacgtgaaa ttctttcttt tccatattaa tcggtctcct ttaagtgagt gttgttttta
    33961 tgtgagggtt ttctttttta gtaattcaga gaatcctaac aaatgccacc ctttcatctg
    34021 taaagattaa catttttttt cgttagatac aacagttttc attcaatttc agataaaagt
    34081 attcaaatta ttccggattc tttttcatcc ttttcttcac attttataac aaacgtgttt
    34141 atttcctttt tcttgtcgct ttctcttctc ctgacgttta tcattctttc ctttgaccct
    34201 ctttgttttc atatgaaacg aattacttgc ttcccttttt atttttagta taataagagt
    34261 caaaggtcag gaatggtcaa tagagatttc accttttcta cctcataaat ctcttaaaaa
    34321 actaggggtt attcttttac ctcatgaaaa acgagatgta aaatatggat gtacccattt
    34381 ttgtgaaagg acgtgaatga ttcatgcttt gtcaaaactg cggcaagaat gaggcaacga
    34441 ttcacttgta tgccactgtc aatggtcagc ggacacaact cgattactgt cagagctgtt
    34501 atcaaaaaat caaaaatcaa caaaatggag gtctgactaa tatggcccaa aatgatccat
    34561 ttggatttgg cagtttggac gatcttttcc gttccatgtc tcgccaaatg caacagcaag
    34621 gaaattatga gcaaacacca ccaacacaat ttggcggaaa caacaacttc aatggtggtc
    34681 agccacctca aggcaataca gaaggtttat tgggagaata cggaatcaat atcacagaac
    34741 aagcacgaca aggtgatatc gatcctgtga tcggacgcga tgacgaaatc aaacgagtca
    34801 ttgaaatttt aaatcgccga accaagaaca atcctgtctt gattggagaa ccaggtgttg
    34861 gtaaaacagc agttgttgaa ggtttagcac aaaaaatcgt agatggtgat gtaccgcaaa
    34921 aattaatgga caaagaagtc attcgtttag atgtcgtatc tttagtccaa ggtactggta
    34981 tacgaggaca atttgaagaa cgtatgcaaa aattgattga agagatccgt caagcagaaa
    35041 atgtgatcct attcatagat gaagttcacg aaatagtcgg tgctggttct gctggtgatg
    35101 gaaatatgga tgctggtaat attttaaaac cagctttagc tcgaggagaa ttgcaaatgg
    35161 ttggtgctac taccttaaat gagtaccgca tcatcgaaaa agacgctgct ttagaacgtc
    35221 gtatgcaacc tgtacgggta gatgaaccaa ctgtcgaaga aacgatcagt attttgaaag
    35281 gtttgcaaaa acgttatgaa gactatcatc atgtaaaata tactgatgag gccatcgaag
    35341 cagccgcaac tttatccaat cgttacgtcc aagatcgctt cttgccggat aaagccatcg
    35401 atttgctaga tgaaacaggt tctaagaaaa acttgacgat ccaaatcgtt gatcctaaaa
    35461 caatcgagaa aaaactgcaa gaagcagaag aacaaaaagt tttagcttct cgagaagaag
    35521 atttcgaaaa agcagcttat tatcgcgatc agatcaataa acttcaaaaa atgaaagaac
    35581 gtcagctcac tgaagaggaa acacctgtga ttaccgaaaa agatatggaa aaaatcgttg
    35641 aacaacggac aggtattcca gtgggtgaat taaaagaaaa agaacagaca caactgaaaa
    35701 acttagcaga tgacttgaaa gctcatgtca tcggacaaga taacgctgta gatcgagtag
    35761 cgaaagcgat tcgccgaaac cgtgttggat taaacaaaca gaatcgtcca atcggctcct
    35821 tcttatttgt tggaccaact ggtgtaggta aaacagagct tgcgaaacaa cttgcctacg
    35881 aactattcgg ttcacaagat tcaatgattc gtttcgatat gtctgaatat atggaaaaac
    35941 atagtgtctc taaattgatt ggttctcctc caggttatgt cggatacgaa gaagctggtc
    36001 aattaacaga aaaagtacgg agaaatcctt acagtcttgt cttgttagat gaagtagaaa
    36061 aagctcatcc agatgttttg catatgttct tgcaaatctt agatgatggt cgattgacag
    36121 atgcacaagg aagaacggtc agctttaaag atacgatcat cattatgaca agtaatgccg
    36181 gaactggtaa agtagaagca aacgttggtt ttggtgcggc acgcgaaggt gttactcgtt
    36241 ctgtattgaa ccaattaaac aactacttta caccagaatt tctgaaccgt tttgacggga
    36301 tcatcgaatt cagtgcatta tcaaaagaaa acttgatgac aatcgtcaca ctaatgctag
    36361 acgatgtcaa ccaaatgctg gcagcacagc aacttcacat cgaagttcct acgaatgtca
    36421 aagaaaaatt agttgactta ggctatgatc catctatggg tgctcgtcct cttcgacgca
    36481 cgatccaaga acaaatcgaa gatggtatcg ctgaatttta tcttgatcac ccttctatcc
    36541 atgagttgaa agcaaaactg gataaagatg gaaaaatcat cgttacttct aaaccagaac
    36601 gtttggctaa agaatcagcc gaagaaacgg ctgaataaat ccagttttat agcgtgagac
    36661 ggtatttctt tgagaaatgc cgtctcattc ttttttcaga aaagtcaaaa tactgttcat
    36721 tttataaaaa agaaattata ataagagaaa caagcaatta aaaatacata aaagaggtga
    36781 gcgccatgaa attggtaaat gtaacaaaca gccattcccg tcttgtatta aaccagcttg
    36841 aaaacactga tgcccatcta gtcaaggtct acacagccgg aaataccact attgtctaca
    36901 ctgaagcccc tcaacataat gaaattctgc tgatcaatga caaacgtaaa atccagccga
    36961 aagaaatcga agatgctaaa aattatttct tagataaaat caaagacgcc gtttaccacg
    37021 aggatgaaat caaagtaatc gaattggcag gccttgttga aatctcgatt ccaaaacatg
    37081 aattaggcgc tacattagcc gtgtaaacaa attttgaaca taataattaa agagcgtggg
    37141 acaaaagtaa a
//
LOCUS       DADLIO010000020        37136 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.020, whole genome shotgun sequence.
ACCESSION   DADLIO010000020 DADLIO010000000
VERSION     DADLIO010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37136
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.020"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(<1..384)
                     /locus_tag="JOX41_001178"
     CDS             complement(<1..384)
                     /locus_tag="JOX41_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448935.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKI"
     gene            complement(569..967)
                     /locus_tag="JOX41_001179"
     CDS             complement(569..967)
                     /locus_tag="JOX41_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HAY6448936.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(964..1737)
                     /locus_tag="JOX41_001180"
     CDS             complement(964..1737)
                     /locus_tag="JOX41_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HAY6448937.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(1734..2417)
                     /locus_tag="JOX41_001181"
     CDS             complement(1734..2417)
                     /locus_tag="JOX41_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HAY6448938.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(2584..3471)
                     /locus_tag="JOX41_001182"
     CDS             complement(2584..3471)
                     /locus_tag="JOX41_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAY6448939.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(3468..4337)
                     /locus_tag="JOX41_001183"
     CDS             complement(3468..4337)
                     /locus_tag="JOX41_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAY6448940.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(4474..5760)
                     /locus_tag="JOX41_001184"
     CDS             complement(4474..5760)
                     /locus_tag="JOX41_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAY6448941.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            6033..6611
                     /locus_tag="JOX41_001185"
     CDS             6033..6611
                     /locus_tag="JOX41_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAY6448942.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            6611..7540
                     /locus_tag="JOX41_001186"
     CDS             6611..7540
                     /locus_tag="JOX41_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAY6448943.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            7537..9273
                     /locus_tag="JOX41_001187"
     CDS             7537..9273
                     /locus_tag="JOX41_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAY6448944.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(9336..10172)
                     /gene="pheA"
                     /locus_tag="JOX41_001188"
     CDS             complement(9336..10172)
                     /gene="pheA"
                     /locus_tag="JOX41_001188"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HAY6448945.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(10169..10678)
                     /locus_tag="JOX41_001189"
     CDS             complement(10169..10678)
                     /locus_tag="JOX41_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HAY6448946.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(10671..11966)
                     /gene="aroA"
                     /locus_tag="JOX41_001190"
     CDS             complement(10671..11966)
                     /gene="aroA"
                     /locus_tag="JOX41_001190"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HAY6448947.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(11979..13070)
                     /locus_tag="JOX41_001191"
     CDS             complement(11979..13070)
                     /locus_tag="JOX41_001191"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HAY6448948.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(13087..14253)
                     /gene="aroC"
                     /locus_tag="JOX41_001192"
     CDS             complement(13087..14253)
                     /gene="aroC"
                     /locus_tag="JOX41_001192"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HAY6448949.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(14255..15319)
                     /gene="aroB"
                     /locus_tag="JOX41_001193"
     CDS             complement(14255..15319)
                     /gene="aroB"
                     /locus_tag="JOX41_001193"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HAY6448950.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(15352..16374)
                     /gene="aroF"
                     /locus_tag="JOX41_001194"
     CDS             complement(15352..16374)
                     /gene="aroF"
                     /locus_tag="JOX41_001194"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HAY6448951.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(17033..18007)
                     /locus_tag="JOX41_001195"
     CDS             complement(17033..18007)
                     /locus_tag="JOX41_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HAY6448952.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(17988..19871)
                     /locus_tag="JOX41_001196"
     CDS             complement(17988..19871)
                     /locus_tag="JOX41_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HAY6448953.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(19889..22114)
                     /locus_tag="JOX41_001197"
     CDS             complement(19889..22114)
                     /locus_tag="JOX41_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAY6448954.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEEKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            22229..23263
                     /locus_tag="JOX41_001198"
     CDS             22229..23263
                     /locus_tag="JOX41_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAY6448955.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(23330..24343)
                     /locus_tag="JOX41_001199"
     CDS             complement(23330..24343)
                     /locus_tag="JOX41_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAY6448956.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(24421..24609)
                     /locus_tag="JOX41_001200"
     CDS             complement(24421..24609)
                     /locus_tag="JOX41_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HAY6448957.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(25049..25177)
                     /locus_tag="JOX41_001201"
     CDS             complement(25049..25177)
                     /locus_tag="JOX41_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HAY6448958.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(25180..26553)
                     /gene="rlmD"
                     /locus_tag="JOX41_001202"
     CDS             complement(25180..26553)
                     /gene="rlmD"
                     /locus_tag="JOX41_001202"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAY6448959.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(26664..27719)
                     /locus_tag="JOX41_001203"
     CDS             complement(26664..27719)
                     /locus_tag="JOX41_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HAY6448960.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(27729..29159)
                     /gene="gatB"
                     /locus_tag="JOX41_001204"
     CDS             complement(27729..29159)
                     /gene="gatB"
                     /locus_tag="JOX41_001204"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HAY6448961.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(29156..30628)
                     /gene="gatA"
                     /locus_tag="JOX41_001205"
     CDS             complement(29156..30628)
                     /gene="gatA"
                     /locus_tag="JOX41_001205"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HAY6448962.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(30628..30933)
                     /gene="gatC"
                     /locus_tag="JOX41_001206"
     CDS             complement(30628..30933)
                     /gene="gatC"
                     /locus_tag="JOX41_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HAY6448963.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(31039..33075)
                     /gene="ligA"
                     /locus_tag="JOX41_001207"
     CDS             complement(31039..33075)
                     /gene="ligA"
                     /locus_tag="JOX41_001207"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HAY6448964.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(33092..35326)
                     /gene="pcrA"
                     /locus_tag="JOX41_001208"
     CDS             complement(33092..35326)
                     /gene="pcrA"
                     /locus_tag="JOX41_001208"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HAY6448965.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            35481..37040
                     /locus_tag="JOX41_001209"
     CDS             35481..37040
                     /locus_tag="JOX41_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HAY6448966.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVVGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
BASE COUNT        10262 a         8064 c         6697 g        12113 t
ORIGIN      
        1 aatcttttgc tgacgtctaa aaatagaaaa agaattttcg tcatctattt gataacgcat
       61 ttgtttttgc agttctgctg cagtcagatg gatcttccca tcgtttgtat cgatcattaa
      121 accttctgga aacagttcaa ccactgctcg atcccaagat tcaagagaaa gctcgatata
      181 atcttttact ggtaattcca attctacctt aaaaaagtgc aaaacagccg acagcccttc
      241 tgcttgatag atttctccta atgttagccc ctctagatgg aactctggtg aaaaatgcag
      301 caatgtttta ttttcctgca attgaacata tagaaatgta gatcgctcaa tcagagtatc
      361 ttttaaaaca actaaaaaat tcatttttct cccccttttt tcatcatttt taaaatagca
      421 tattttgaaa agaaagtctg atgcttagag tagaatttca taaaaattta ctatttcata
      481 agtattcacg agaaaaatac aaacaaaaaa gcggaaataa cgctcatccg ccttcttgtt
      541 tgtgtttatt tcctcttcaa acgcttgtct atgattcaga cttttctcta tcgttatttt
      601 catctaaaag ttcttgcatt ccgataattt ctcgatattg atgaatctta gtgataccaa
      661 tgactttgtc tacatcaata ctaaaacaaa taccattacc tggaatatcg atgttgatgc
      721 cttgaccaat cgcatccatt actttattcg tcaaactatc gggtactaat gtcaacacaa
      781 tatctttttc tggcgaaatg tccaaaccta aaaatttccc tgaatcatgt acaccagaac
      841 ctcttccatg taagatcgtt ccgcctgctg cacctgcttc ttttgaaaag tcgataacat
      901 cttcgcccat tcctccgtca acgatcgtca caatcatgtg aagattcaat gctacaagat
      961 ctttcatttg ctttccccca atttttgcaa tctttctttt tcgattctgt ctttttcatc
     1021 ttttcgttta taaatatatc ctagtactaa agtggataat attggtgtca atgcaatcat
     1081 tgcaaccaca ccaaacccgt caatgatcgg atctcttcct tcaatttgtg cagcgattgc
     1141 cacgctcatt gataaaataa atgtcgaaca catcgggccc gttgctactc caccgttatc
     1201 aaaagccatt gctaaaaaga tcttgtccac ttttcgtcct aaaataaatg ctagcccgta
     1261 tcctgggatc aagaaataat aaagagagaa tccgacgagc aaacgccaca tagacaatcc
     1321 tactgctgcg ccgatcccaa ttgaaattac catcagcatg attttcgatc ggattctccc
     1381 ctcgctcaat tcttcaacct gtttgatcat tacatgaatc gccggctcag caaaccctac
     1441 taagaacccc attaaaaagc caaggggaac cagtatataa ttgtaaggca atcccgcaat
     1501 agcactgcct aaatgctgtc ctaccggtac ataagccata ttgactccgt gcaggaaaag
     1561 gatcaaccca atagtcgtta tcaagaaacc tttcataatg tcaaagaaac gctttttgcg
     1621 catacgaaaa ctaatgatat tcattaaaac aaataggatt acgataggtg ccactgccaa
     1681 aatgacttcc atggtaacga tttcgattcc atctatcact tgctgccaga aactcattgg
     1741 aagatcaccc ccaaaatcat cacggcaaga atcggcccta acgaagcaat accgaccatt
     1801 ccaaaactgt cattttcatt tttcttttgt ttgatcatac tagtcatccc tccggcaagg
     1861 gccaagataa atggaacagt tactggacca gtagtcactc cccccgaatc aaaagcaatc
     1921 ggcataaatt cggaactggt gaaaaatgag gcgatcaaaa cgcctatgta gcctatagcc
     1981 atcaattgat aataggatag cttgaatacg acccgaagca gcgcaaaggc tagaaatact
     2041 ccagtgccga cgctgacgat cccaatcagc aacactctgc caatctctcc gtcagatata
     2101 tcatatactt gttgtcccaa aacttgcacg gaaggttcag caatcgtgat cacgatcccg
     2161 atagcaaatc ccaaactgac caaaacggtc aaacttttct ttttgatcat atatttccct
     2221 actagatctc cgacttccat catagaataa tctgctccaa acaaaaagag cgtcattccg
     2281 atcatcatga ttgccgcacc aaccagaaat gaagcgaggt cttctccttc taacggtgca
     2341 aaaacaaacg ttaaaatgac aatcaggaca gtcatcggca atatagcagc aatcacttct
     2401 ttaaaatttt ttagcatgta tcctcctcct ttactcttta agtttacctt aaaatgaaag
     2461 agttttcgag cacaaactta aaacgttatc atttaatttt tctcaacata aaataacaca
     2521 cgtcccaaaa gtatcttttt acttggaaaa atgactttga aggaacgcgc ttattgtgtt
     2581 tttttatttt acagagccga tcattccttg aacgaattgc ttttgcaaaa caaaaaatac
     2641 gatggcagtt ggtaaagtag cgatgactaa tccagccatg atcattccat agtctggtgt
     2701 ataggaagca cccatagcag ataaaacaag cggaaccgtc cgtttatcag gagattgcaa
     2761 agctactaag ggccataaat aattgttcca gctactcatg aatgtgatga ttgcagccgc
     2821 ggcataggta tttttagccg tcggcatata cactctaaaa aaaatactta gttcttttag
     2881 accgtctaat cgagcggctt ctactagatc ttttggaaaa gatttaacat tttgtcgaaa
     2941 gaagaagatc aaaaaagcag tgctaacaga tggcaggatg acaaccaaga aactgttgat
     3001 tcccaaaacc gttccgttca attgtgaaaa cattcgatat aaagggatca tcaatgccgc
     3061 aaaaggaacc atcatcgata gcagtagaat attgaaaatt aggtcttttc gtttactttg
     3121 ataaatctca aatccatatc ctgccattga cgaaatcagc aatgcaaaca cagtggtcac
     3181 caaagcgatc atcgctgaat tccaaaggga acgagtaaaa ttcagctcat tggaaaacaa
     3241 attttgaaaa ttgatgatca agttactgcc aatctttatt tttcccgatg tgatatccac
     3301 gggtgtattc gtcattccca aaaccatcca gacaaaaggg aaaatggaaa taaatgatag
     3361 gatgcttaat gctgtatact ttaatactga cccaattgtc gaacgaagtt ctaatgcttg
     3421 ttttttgacg ttggggcgtt cgattgtttc tttttctacc atatttttca tcgactttct
     3481 cctcctactt tcgtttggat tatcgacaat atcacaataa aggaaacaat aacaaaggaa
     3541 actgctgccg catatccaaa attaggcgtg aatttataac tcaaattata gatgtattga
     3601 gatagggtgg tcgttgcatt tgctggtccc ccgccagtaa tattttgtac ttcatcaaaa
     3661 agctgcaatg tcccgatcgt cgaagtaatg gaagtaaaca aaatgattgg ttttaaattt
     3721 gggatcgtca ctttgataaa ctgctgccat ttagaagcac cgtcaataga tgctgcttca
     3781 taaatctccg aatcaatatt ttgcatgcct gaaaggaaaa aaatcatatt gtatccagtc
     3841 caacgccaag tgatcgaaag aatgatcaga actctcgccc aaattggatg agtcaaccag
     3901 ccaatcggtg tgtcaatcat accaatgccc aacaacaagt tgtttacaag gccagattga
     3961 gaaaatagac ttttcatgat cagagaataa ctgaccatcg aagtgataca tggaagaaag
     4021 atagcggttc gaaacaaccc tttatatttc aactttttat catttaaaag gttggaaata
     4081 aaaagtgcta gaaacaacat gatcggtact tgtacaagta aatacaggaa tgtattaaaa
     4141 aaagcttttt taaaagttgc atctgtcaac atccgctgat aattacctaa cccgttaaat
     4201 gtcatattga cagggggacc actttgaaaa gacgtgatca aagccaaaac catcggaata
     4261 aaaaccatga ttgatatcaa aatgactggc aagattaaaa aagcatgccc gtttttgaat
     4321 aaatctttct gcttcattct tttccctcca attctatcat tgattatcta catgaaaaga
     4381 caagaaagac aatatctgta aggcagacgt gatctttttt gtcttttcgt ttgtctgatg
     4441 aaaaagcgaa gaaattcact tttttaccac cgatcaatta gccaattgtg cttctacttg
     4501 tttttgtgta tctgctagta ccttgtctgt ctcttctcca ttgatgattc gatgaagagc
     4561 ttcagctacg actgcttcaa ttgcataggt ctcatgtccg taattcactt ctggtatttc
     4621 agatgtccat gttgaaaaat cgtcaaagat cttttgacca ctgtaaaatt cagaagcttc
     4681 ttgataagct tcttgttcat tcgcgctaag catcgtagat actagtccga tttctttcgc
     4741 aagagtgccc atcagttctt cattcgaagc aaacgttgct tctaggaaat ctttcgctga
     4801 atcttctcca gctactcctt tgatcacata ccagccagcg ccgccaaggt tagaagcttg
     4861 cgctttttgc agattttctg gaagtgcagg tattggtgca atcttccatt ttccagattg
     4921 gttttctgct ccttggatcg ttgaagaata ccaagcgcca gttgggctag aagctactgc
     4981 tcctgattgt atcgcagtta ctccagcatt ccagtcagag gtttgttcga ctagatcttc
     5041 tttcaaaaga gtggcaaaca attcaagacc atactttaaa gatgcattgt cttggatcgt
     5101 gactgtctcc ccatcttcag atgtatacca ttctcctgcc tgttgcataa tcatccttac
     5161 tcgaccaagg tcagaaggat tgacttcagc gattttcttt cccgtctttt ctttgacatc
     5221 tcgcgctact tgaatatact cgtcccactt cagattctcc atatcctctt ctgtataacc
     5281 tgcttctgcc atcagatccg tacgatagaa gtttgctgtt acgcccgaat cgaaaggaac
     5341 accgtatatt ttatctccta ctttgtttac cgcaaattta tacggtgcaa aatgatcttc
     5401 ctttacaata gcagacaaat tagcgaatgc atctggataa gaagtcaaat agccttgtat
     5461 cctataatct tcaatcaaga cgatattggg caatccttct gtattcccgc tcgctaaagc
     5521 ggtgttcagt ttctgaacga tatcatcctg agacatcgta acaacttcta tctctgtttc
     5581 ttcgttctca taaacttttt ttgcttcatt cactgctttg atattgaatg tctcatccca
     5641 cgcccagaca gtgacttttt cttctttgtc tgctgtacta ctagcacttc cgcatcctgt
     5701 taagaaacct gatgctgccg ctaaacaaac gactccagca attaactttc tgatgttcat
     5761 ttttatccgc tccttttcca tccattagtt gtttacgttt gctacattca tcataccaaa
     5821 atttgaaaac ggtttcttta ttattcagat acttcaaaaa tttctcctaa aataataaaa
     5881 aaatacaaat caactatgac aaaaggaata atcttagcat ctagaccaaa gatcgaaatg
     5941 gtgaggtttc tttaaaataa aaatatcctt gcattttctc ctagaaataa gtatttttaa
     6001 attacaagac tattcttaag gcgggtaaaa aaatgccaat acgcgtaatt cttatcgatg
     6061 atgaacagac gattttagat ggaatgaaac agttgatcaa ttggtctgag cacgggtttc
     6121 aattaatagg gactttttcc agtccgctga aagcgcttga tttttctttg gtacatgcaa
     6181 tcgatatcgt ggtcacagat gtaatgatgc ctgaattaaa tggaatcgaa ttatcgcggc
     6241 tattaaaaca gcaacaacct gaaacacaga tccttatcct ctctagctat gatgaatttg
     6301 atatggttaa agattctttt aaagaaggcg tcgctgatta tcttttaaag cctcgattga
     6361 gtcctgattt ttttctaaat tccttaactg ccgtttcaca aaaaatcaaa aaaaagccca
     6421 acaaaagccc aatcaccaat cgttatgagc agatctgcga gaatctttca cagcagattg
     6481 ctggacaaac tcgtccattg cttgaccctc ttctttttga acacaccttg tttttctgtt
     6541 atataccgaa aaacggccat tcagttcaaa acaaggctct aaacaaaaac agtcgatcac
     6601 ccattcattg atggatagcg acgattcgtt tactatttat cctgtttcta ccttttcgga
     6661 agaatccggc tatgtaatca atactgattc caaagataca cttaggaagt ttgttcaaaa
     6721 gtttcgtcaa gaagtttttc caggtgattt ttttgttgtt tctgattctt ttgcaatcca
     6781 agatatcaat gaaatattcc aagagatcag aaattgcacc aaaggacaac gtttctatca
     6841 taagggaaag aaccttgctt atcagcatga acttcttccg ttattaacca accacgagca
     6901 gcaagcaagt agttatttaa caaaaatcgt tcataaagac tacgctttag ctgtcaaaga
     6961 acttgagaat ttcttcacga cgatattgga acagcctatt gatccagctt atttgaaaca
     7021 tgaggcaatc aatcgtttct atgcattact caacgctttg gctgacgagc atgttgggaa
     7081 tgaagaactt tctttgctca agatcgccct tccttcttta ttagccgatg ctgagtattt
     7141 cgaagatttt tctattcttg tcaaagaaac acttgagaaa ctcacccact tttctgcaaa
     7201 tgcaaaaaaa gacaatttcg atatcttgac tttgatctac gagttcgtcc aggaaaatta
     7261 tgagaaagaa atcaatttac aacttttatc cgaaaaatat catttttcat atagctatct
     7321 ctcagccatc tttactgaaa aatttggtat caacttttca aaatatctaa aaaaagtccg
     7381 tatcagtaaa gccaagctct ttttgacgga aacacggctt actttgacgg aaatctgtga
     7441 gaaagtcggc tataccgaac tgggttattt ctccagagtt tttaaagaag agacaggaat
     7501 gacaccttct caataccgta aaggaacttt tgtaaaatga gaaaaaaaat caaagagcat
     7561 gaactctttg ccaaacttct gttcattttg ttcatcggtc tttttctgca agccatcgtc
     7621 atttctttgt ttatttatca tcgatcaagg gatgcctata tccagctgtt caatcaatcg
     7681 aatgatgtgg tactaaaaaa gattcaatct gaatttgaaa gtttgaatga tacaatcgag
     7741 aatacattag ccgcttttga ttctaatcca gctgtcaaaa gctatttttc caatgatcca
     7801 gcccaacata tggaacagct tcagcaacta agaacaatcc aaaaaatgaa tgactctctt
     7861 tcaaaaatcc atccaatgat cgattacgat gtattgatct ttggagaaaa tggaagaact
     7921 tttgtcggaa acgacatgct cactgccgta tctgccgatt ctttttttca atctgcgatt
     7981 gctcagagag tgaatgaacg tgctgctgat acacaaatgc tttttgcaca ccacggattg
     8041 actcttcgcg ataagaaagc acccagcgtc ttctttgtca aaaaactgaa aaatacattg
     8101 aatcacgttt acggatatgc tgttttatcg atctcatcca agcaactagc gaatcttttt
     8161 caatctgtag taaatcctga gatatcgaag atctccttca tgaacgaaga acagacgatc
     8221 atcgcatcaa atgaagaaaa tacaattggg agccgatcaa tgattttcaa aaaactaaca
     8281 gtaggtgaaa caacgatttc aaatggacag cagttgaccc gtcttcctct gtaccgccag
     8341 gattgtacat tactcagtca agtcgatctt cattctttat ctaaccaaat gggcgtgatt
     8401 tttccgatta ttttgtataa tatcgtgaca cttgcttttg ctggctcatt ggtatttatg
     8461 tatttggatc gacacacaaa atcgatctac cgcttgattg attcgctaaa acggctagag
     8521 gaagatggct taaaagctac tgttcctgta caaggaagcc atgaagtcca attgctaggg
     8581 aatacgatca atcaattgct aagtaatgct cagcatcatt atgaacagac gatccaagac
     8641 gaaaagaaga aacgttcgct tgaaatccaa actatgcaag cacagataca gccccatttt
     8701 atttataata cgctgactag cttgaaattt ttgatttggc agaaaaaaac agatgaagca
     8761 gttcaaggaa tcgacagttt cattacttta ctaagaagta cgattgggaa aaaagaagaa
     8821 gtgattccag tcaaggaaga aatcaaaagc gtacaaagtt acatcgatct tttgagtatg
     8881 cgatatggcg aaagaatctc ggctaaaata atgattcctg atgaactgca gtcattatct
     8941 atgccgaata tgatccttca accaattatc gaaaacgcct atcttcatgc ttttcacaat
     9001 aaaacgcaag gattcatcac ggtgtacggc aaaacaaaaa atcagcttct tttattcgaa
     9061 gtgattgata acggcgatgg cttcgatact gaaaatacca aacaaaaaaa tgatcatttt
     9121 tcaggaatcg gcatcagcca tgtagatgag cggatacgcc taatgtatgg cgatgcatat
     9181 ggcttaacga tccaatcagt gattgggaca ggaacgactg taacgatttg tctaccgctt
     9241 cttcctaaaa atcaatcaga atatcaaaaa taaagaatag ccaagcgctg atttttttat
     9301 tttaagttaa ataaatcaat cagtattctt gactttcatc tacgcgtctc ttctactgtc
     9361 agcactggat aacagcccaa tatttgactt tctcctccga gcatcttgat ttcttggagc
     9421 gcattctcta ctaatgtcat tggacggtcc aacaacaaat cgatcacgaa aaaatattct
     9481 cccaagctag ttttcaatgg tcgggattca atcttactta agttgatttc ccgccagcca
     9541 aaagctgcca gcattttatg aagcatccct ggccgattag caggtagtgt caagatgaca
     9601 ctcattttta ctggagctga ctgctggctg gtcatctttc ggtcaccgac gatccaaaaa
     9661 cgtgtctggt tcaactcatt atcttggata ttctcagcta agatctccaa tccaacatgc
     9721 tgtgctgttt ctaatgaagc aatcgctgct gcgtcttctt tcggatgttc tgctacatac
     9781 attgctgcag cagttgttga ttctgttgct actaaaggaa cattaggata atgcgtttct
     9841 aaaaactgtt gtgattgtgc tagtgcttgt ggatgtgaaa ggatttttgt aatctttgtt
     9901 gctggattgc ctaaaagctg ctgcttgata ggaagaacga tttcactttt aacttcgact
     9961 tctggatgtt tggaaagaag atcgattgtg tgatgaacag ctccttccaa tgaattctct
    10021 acaggaacga cagccagatc gacttgtttg cgaaacaaag cgcgcaaaca aacagggatg
    10081 gaagcatacg cagtcaattg ttctgtagga aatagctgac aagccgcctg ataagtgaat
    10141 gaactttctg gccctagata gctgacgttc atatgctttt gatcctttct ataatggtat
    10201 cgatgatctt ttctggtgtt tgattggtcg tgttgattcg atgtgtcgca ctttcttcat
    10261 accaagaaag tcgttgtgcc aataatgctt ttatttcttc tcttgttttt ccaagagcta
    10321 aaggtcgaat agacgtttca tcttgttgga tacgatcaac tagacagtcc gcttctgcct
    10381 ctaagtaaag aacaatcggc tgtgttttta aaaaacgccg attttctgca ctttggacaa
    10441 tccctccacc agtcgcgata attttgtctt catttgacag ctttcttaaa atatctgact
    10501 ccacttttcg aaagcttttt tcaccgtaat agtgaaaata ttcggcaatc gacaattgga
    10561 tatgttcctc aatctttgta tctaaatcta catactcttt ttgtaaacat tgagctaacc
    10621 ctttaccgat tgttgttttt ccagcgccca tgaaaccaat cagcaaaatg ctagccatga
    10681 gcttctcctc ctgacacaag ttctgctaaa tcgtcaaaaa atgccggata agagattgaa
    10741 acagcttcag ctccttctag ttcgcaaggt ccatcagcta tcaaagcagc tacttgcagc
    10801 atcataccga ttcgatgatc gcctctgctg gacacttttg cgccatgcag aggtgtcggc
    10861 ccatggatga tcagaccgtc tgctgtcgct tttatctttg ctcccatttt ctgtaattct
    10921 tctgccaccg catcaattct gttggtttct tttactttta attcttctgc gtctttgatg
    10981 atcgtgattc cttctgcttg agtagccact aaagctagaa tgggcaattc atcaatcaga
    11041 cgcggaatga tttctccacc aatcgttgct ttcttcaaat gactcgtctt gacacttaaa
    11101 tcagccgatt ggttctgttc attgtgattc gtctgggtaa tcgctgcgcc catctcctcc
    11161 aacacatcta agataccagt tcttgttgga ttgaccccga cattttttaa caacagttgg
    11221 ctttccggaa caagaagtcc tgctgctaga aagaaagcag ctgatgaaat atcacctgga
    11281 acagttatct gttgaccagt taatttttgc ggtccggtca ctatgatcgt tttatcttcc
    11341 actgtgatcc ttccgccaaa ttgacgaatc atttcttccg tatggttacg ggaacgttct
    11401 ttttcaacga ttacggatgt gccttctgct tgtaatgccg caaacagcaa agcagatttg
    11461 acttgcgcac tggctacagg catattgtat cggataggtg ataaagagcg ggttcctgtc
    11521 acagtgattg gtagatactg gtcattttct tctccttgca agtcagcgcc catctcgcgt
    11581 aaaggttcca tcactcgccc cattggacgt ttagacaacg aagcatcccc gaacagagta
    11641 gtcgtaaaag gctgtccagc caaaataccc atcaataaac gtatggtcgt accggagttt
    11701 cccatgtcaa ttgattcggt tggttggaca aatgagtggc taccgcgacc atgaatcttg
    11761 atcacctctt cctcttcttc gatctcgaca cctaattgtt ggaaggcatg taaagtactc
    11821 agacaatctt ctgcgcgcaa aaaattttgt atagtcgtcg ttccttcagc aattgctcca
    11881 aacatgatgc tgcgatggga aattgattta tctgctggta tcctaacagt ccctcttaat
    11941 ccatgtattt gttgtaataa ttgcatttat ccagcctcct atttgatcca gcaatgataa
    12001 ctggtattag acataatgat tctttttgct tgtaacaaat cctgttggtt tttaaaactg
    12061 atttgcagta ttcctaaaat atcttccctg gtctcttgga tcttcaaatt aatcaaagaa
    12121 actcccgctt ttccgatcag tccagttact tctgcaataa cgccaggttc atctggcaca
    12181 tcgataaata aatcaaaaaa ggcaggaatc gcgccttgct tatggacagg caactggtct
    12241 cgactttctt ttgcccgatt gaaaaaagaa aagatttccg attggttctc agtcatgatc
    12301 cattctgcta tttgtgtcat ttcttgttgc caatctgcca atcgttccaa taatatctgc
    12361 ttattgctca acaaaatatc tgtccacatg acaggatctg aggaagcgat cctagtgata
    12421 tctcgaaagc ctcctgctgc cagttgtttg gctcgcggat actcttgatt gaattgttct
    12481 gcctgattga ctaagccagc tgccagaata tgtggaaaat gacttagcat tcctgttata
    12541 cggtcatgtt ctcttgctgt aagagttaca tattttgctt tggttccgca aaatagttct
    12601 tgcagttttt caacatcttt tttcgtcttt tccaaaggtg taaagatgta ataggcattt
    12661 tcaaatagtt tagcatctgc tgcctgtata cctgatttat gagaaccagc cattggatgt
    12721 ccaccgacaa accgaagatt tttctgctca gcggatgtca cgacttgctg cttcgtactg
    12781 ctgacatccg taatgatgac gtgatcagac aagttgattc tttcaaggac atcaagataa
    12841 gctaaggttg tacggacggg aacggctaat aagataacgt ctgcttgttc tgcacctgtt
    12901 tcaaaatcac ttgcaacgta atcaacgatc tgctgttcta ctgcttgctc acgggttttt
    12961 gactgactat cccaaccaac tactatcagt tctggattgg tctgacgaat acaaagtgcc
    13021 atagaagcac caatcagtcc aagccccacg ataaaaacat gttgtgccat cttatttgcc
    13081 ccctttttag taatgtttca agtagtcacg gtactccttc actgcagctt tcaactcaac
    13141 aagcgaatca cttgggaatt ttgacaatag ctctgtcgct accacagtgg ctacaacatt
    13201 ttccgcaacg acgctagctg caggaactgc tgtactatcc gaacgttcta cacttgcttt
    13261 gtaaggttct tttgtatcga tatcaacact ttgaagtggc ttgtacaatg taggaatggg
    13321 tttcatgacc ccgcgaatga caagtggttc gccattggtc attccgcctt cgaagccgcc
    13381 tagattattg gtacgtcgga aatagcctct ttcttcttcc cataggatct catccatcac
    13441 ttctgagcct ggtaatgaac cagaagtgaa tccgacccca aattctacgc ctttaaaggc
    13501 attgatacta accacagctt gtgcgatttt ggcatctagc ttcgtgtccc attgtacgta
    13561 gcttcctaat ccagctggaa cgcctccaac gagcacttct acaattcctc cgatcgtatc
    13621 tccatttttc tttgtctgat cgatcaaatc ttttattctt tgctcaactg ctggatcaac
    13681 aactcgtact tctgacgctt cagaaatttc tttgatttct tgaatcgaga tatttccagg
    13741 tatttctgct tggattccac caagacaaat cacgtgtcct gctacgatga tgtcaagttc
    13801 ttccagaatt ttcttggcaa ttgcgccgat tgctacacgc atggtcgtct ctcttgcaga
    13861 ggaccgttca agcacattcc gaagatctcg atgatggtat ttcataccgc ctaccaaatc
    13921 cgcgtgtcct ggacgcggac gtgcaactcg ccgcagtgat tggtcttttt caggcacttc
    13981 tgctacagac atgacagttg tccaattttt ccaatcttta ttttctacca ctaaagtgac
    14041 aggtgaacca attgttttgc cgtgacggat gccagacgtg atccgaacac gatctttttc
    14101 gatcttcatc cttcctcctc tgccgtaacc agcttgtctg cgagcgagtt cgtgattgat
    14161 ttcttcttct gacagaggta atcctgctgg tagtccttca ataatggctg ttaattctgg
    14221 tccatgggat tctcccgcag tcatataacg catcttacag tcctcctaag taatctttga
    14281 atgtctctgt gggaacagga acgatttttg cttgcccaat cttttctagc aagatgatat
    14341 tcaattggct tcctcttgct ttcttatcat gggttatcgc gtggaataat tcatctggat
    14401 gacttagatc gtacgtaatc ggcagatgga atttttgaag tatcctttct aaagcagctg
    14461 tcgatccagt tggagacaag ccgatttttt ctgcatgaga agtgatggct accattccaa
    14521 tagctactcc ttctccatga ctgactaccc catatcctgc tgtattttca attgcatggc
    14581 caattgtatg accaaaattt aaaataagtc gatttccttg gtcaaagaca tcttcttcca
    14641 ctacttttcg tttgatttcc aacgtagcag taatgattgg aacagcatgt tccagaagat
    14701 ctttttcgtc tttcagctcg ttcagctgtt tccaaagcgt tgcatctgct atagctgctg
    14761 atttgatgat ttcagcgatt ccttctcgta aacgacgtac cggcaaagtt tttagaacct
    14821 caggatcaat caatacacca gctggctggc taaatgttcc gacaaggttt ttcgctttgt
    14881 ttgtattgac tgctgtcttc ccgccaatac tagaatctac ttgtgcaagt agcgtagtcg
    14941 gaatttgaac gaaatggatc ccacgcatga acgtcgaggc cacgaatgct gctagatcac
    15001 ccaccattcc tccaccaagt gcaagtatcc catcgctgcg ggtaaaatca ttatctgcta
    15061 aaaaatcgta taactcagct gcttgttcta aagatttact ggtctcaccc gccggtacga
    15121 ttgaaaggac tggttcaaaa ttagcttgtc tcaattggaa catgattttt tctgcatata
    15181 gtggagcaac gtttgtatca gtgatcacag ctactttttg aggtctccaa atcgtttgaa
    15241 gccatgatcc agcctgttct agtgcgcctt tttcaatatg aatatcgtat ttttggttat
    15301 caacatgtac agtaagcatt cgtttcactt ctttctttta aaaagctgga attaatcgag
    15361 tgtctgaatc ttttccattg cttctttcat gatcgcaact tctttcatca tgcgtgagta
    15421 agtcttttca ttcaacgatt ggggaccgtc tgaccaagca tttgcaggat caggatggat
    15481 ctctacgatc atgccatctg ctccgcttgc cacacccgca cgagccattg gtggtacaag
    15541 ttcccaaatt cctgtaccat gacttggatc aacaatcaca gggaaatgag ttaatttttt
    15601 catcaatggg acagcactta aatcaaacgt attacgtgtc gctgtttcgt aagtccgaat
    15661 cccacgttcg ataaaaatga caggagattt gtcttcgact gcaatgtatt ctgcagcatt
    15721 aagccattca ttgatcgtac cggaaattcc acgtttcaat ccaacaggtt tacctgtttt
    15781 accgacagca gatagcagtt taaaattttg catattacgt gcgccaatct gtaggatatc
    15841 gctgtactca gccaccatat cgatatgccc ttcatccatc acttcagtaa tcactttcat
    15901 tccaaattca tcagccgctt gacggatgta tttcaatcct tcttcttcta aaccttggaa
    15961 agcatatgga gaagtacgtg gtttgaaggc accacctcgc agaatttttg cgcccccggc
    16021 tttggccatt cgcgcacatt ctctgatttg gtctaatcct tcgatagaac aaggaccagc
    16081 catcgtcacg aaactgccgt caccaatttt tactccgtct acatccacga ctgtattgcc
    16141 aggatggaat tctcgagaag tcaatttgta tgtgtttaaa atacgcacag cattttctac
    16201 tccttcatag cgtgtaaatg ctccttcttg taaacttcgc gtatcacctt ttagtccaat
    16261 cactactcgt tctgttcctt gatcgattga gactttgaat ccttcttttt cgatatgatc
    16321 gacgactttt tttatttgtt cttccgttgc ttcttttttc ataattacta tcattgtttt
    16381 tcccgctttc ttttgtttac ttatctatct tggctgattt tctctacttt ttcaaggtgg
    16441 ttttacatta attcctacta aatgaccgtg tcctgttgtt ctcattttcg ctccttcttt
    16501 cctacttatg acccagataa tcaacaaaaa aagatgtccc tgtaggaaat tgcctctaca
    16561 gtgaacatct tcaacgagcc ttaaaaagcg ctgcaaaaat ataaaatagc cactatagat
    16621 gaatttctct acgtggctgt aagtcgtgtt taaaaatctt tagccatcat agatacaaac
    16681 ctggtttgtt tgtacccacg aagtcatgaa tacaaaccta tctaaaatag ctaaagtaat
    16741 acgtattcag ttttgtaagt tttctagatt tcataaaaaa tcgctccaaa ctgatgtaag
    16801 aattgtacct agtatagaca taaaaaaatc gactgtcaat catttttatg aaactttttt
    16861 taattttctg atagttaact ttgtttttca gaaaaataac aattggtttt attgaagaaa
    16921 atagtcatga acaaaagtat ctgagaactt ttttactctc ttgttcatga catatagaat
    16981 aaagcagctt tgtcttgtaa actccgtttt tcaaataata atctaaagat tgctactgaa
    17041 taataaagcc gatttcatgg tcctcttcgc tgctgattcg gtaaggtgac tcaacatccg
    17101 ctccccagct attgataccc ccgactcctc ttacttttgc aaaaatcgta agaaccgttc
    17161 gtctttctgg cggtagttct tctatatgtg ttgcctgttc cagttcttct gctttgaatg
    17221 gtaaagcgga aaaagcaaat ggcgtatcct gctgttcaaa tcgcaacgaa aaatcttctt
    17281 gatctttatc cgtattatcc aacgtttgat ttcttgttag ttctacccat ttcgtttcca
    17341 tatgcatgcc gcattcttgg ggaacaaggt atggggaaac ggggagtcct gccactttat
    17401 aaataccttc gacaccacca gccatccgat ccggatatgt ttcccctgat aggccttcat
    17461 actcaaaaaa ttttgctttc gttggcataa tgaaccttaa acccaatgcg ggtaattccg
    17521 gtaatccttt ttgtccataa taatgcatat tgacaagcat tttaccctct ccagcgattt
    17581 ggtaggaaat tgtcacttgg gtttttggta ctgtgttgat ttccagtgta aaaatgattt
    17641 caaccgtttc agcgtattca ttacttgaat attgattatt tactggagca atcggcaaat
    17701 cgatcttttt attgtccacc agtacttcta tttctttgac ttttggatac aatccggctc
    17761 ctaaccacat accggattta aatccaaatc cgctacctct gtcattatcg gtcgttgctc
    17821 gccaaaaaac tggaagtgtt tcccggtata gccattcttt tccgttttta ttgagcgatt
    17881 ccagtccgcc tcttgtataa gaaaaaatat aatgcgtatt ccccgatttg acacctaatg
    17941 tacagtcgcc gaagacgatt gcaacttttt ccgtatccat atgactttta tttactgtat
    18001 ttttcataat aatatcttac ctcctgcatg gcgggttttt cttgtccatc tgcaaaaacg
    18061 atcccattcc ctgagaattc atagtcactt ggtttatcgt caaagtcacc gccatagcgc
    18121 atcacttctc tgcctgtgat tggatcagtc acttggatcg cctgatcttt aaaatcccat
    18181 atatagcctc cttggtacat ttcataacga tcaagcaacg tcatgtaaga atccattcca
    18241 cctaacgaat tccccatgtc atgcatatat tcacataaga tgaacggttt ttccgcttta
    18301 ttttcaaggt agtcaatgat ctcttctggt ggcgcataca tgcagctttt tacatctgaa
    18361 atcgaatctt cgaatgctgg atttggaaaa ttcccttcat aatggacaag tcgatcgggg
    18421 tctacttttt tgaagtaatc gttcatttgt cgaatgtttt cttccgcata agattcattt
    18481 ccaagagacc aaaaaagaat acttggatgg ttttttaatg tttcgaaatt cgtttttgct
    18541 cgatcaagaa cagccgcctg ccactgaggt actgcacctg gtacgttgta agaaggctca
    18601 aatgcgccca ttttttgcca tgagccatgg gattcgaggt tcgtttccgc catcacatgg
    18661 attcctgctt ggtcgcataa ataataccaa gtgatctggt tggggtaatg agatgtccgt
    18721 acgccgttga tctttgcatt ttttatgata gccaaatctt tttccatatc ttctatagtg
    18781 atggcgcgtc cttttttcgg atgccactca tgtcgattta ccccgttgat aatcatccgt
    18841 tttccattga agtagatgat tttatctttg atttcgattt tacgaaaacc gaaggaatag
    18901 tcaatatact ccgttactct tttttcttcg tctatcgtct ccaattcaag cttatataaa
    18961 ttgggctgaa aatgccccca cagtgccaca ttttcaaatc catcgatgcg aatcgtcatt
    19021 tgctctttta acggatattg ctgttgatag atttccttcc catcaggatc tagtatcgct
    19081 acattcagct gactgttttt ggctacttgc tcaaaagaca aatctacttc aagtttgcca
    19141 ttttgacatt tgtcatctaa gcgaggtttg atccaaagat cttctaaatg gttttgtcct
    19201 cgagcaacta agaagacatc tctgaagatc ccaaaaaatc ggaaaaagtc ctgatcttcc
    19261 aagaatgcag ctgtacttct tttgtaaacc tccacagcta gaatattttc ttcttccaaa
    19321 taaggtgtta aatcaaattc agacggagtg aacgaatctt cggcataccc gataaaatga
    19381 ccattcaacc aaataaacat tgcttgttct acaccagcaa aatgaatcga gatttgtttt
    19441 ccctttagac cttcttctaa tcgaaaagtc gtcaaatacg aaccaaccgg attgtcttta
    19501 gcagctgaaa agatcccttc cgcctctttc tcagggcttg tcgtgaaagg gggacggcga
    19561 aatacatgtc cctcccacgg atacatcgta ttgatgtaat ggatcttgtc ataatttgct
    19621 aattcaatat gactaggaac agtgatttca tcaaaagaac aggcatcaaa atctttttta
    19681 taaaatgttt ttggtcgtac cgaaggattt ggcgaataac aaaaacgcca tgatccattt
    19741 aaagactgtt taagggagga tgtggtttct acttcttccc ttgttgcata acaaacatga
    19801 tcgctatgtg catttgattg gttcactcta aaaacttgtg gatcatctaa ccattttata
    19861 tttgctttca tacttttttc cttctctctc ataacttttt gaaatgaagc agttctgttt
    19921 ggaaatcacc ttgaaaatcg gggaagtaaa gtccaactgt catcaattcg gcccccgaaa
    19981 atatccgctt cgaggtctgt tcctgataaa gtgcctcatc atctaacccc atcagatata
    20041 cttcatggaa cgctggttga gctgaagcta gtatcctccc taaaaacaca atagcttcat
    20101 cttgtttagg agacacaaac atccatgcgg caatattttc ttcaaaagga ctcgccaaac
    20161 gataataatg gccatactgg atcaccggac gaatcgtttg ataggatata atttggtctt
    20221 ttacttgctt ttcttcttca ggagacagct ttgtcaaatc cagttcataa ccaaaaacag
    20281 cgctcatagc tgtttctcct cttgttttca acgaagtaga tctgtcggtc tgatgatttg
    20341 gtacagctga tacatgagct gtgatggacg aaatcggata agcaaggctt gttccatatt
    20401 ggattttcat acgctccact gcatccgtgt tatcacttgt ccatgactgc ggcatataat
    20461 aaataaaccc ggcatcaaac cgtccacctc caccagaaca gccttcccat aagatttccg
    20521 gataatcagt tgtcaaatgt tcaagtagtt cataaagccc gagcatataa cgatgcgcta
    20581 cttctccttg tctctgtggg tcaagggtaa tcgaatagac atctgaaagc gaacggttca
    20641 tatcccattt gatgtagtca agaggaatcg tatctaaaat ctttctcatt tgtttctcaa
    20701 tcgtctgccg aacatctaac cttgtaaaat ccagtacatg ttgtgatctg gaagcagaag
    20761 gcattctacc tggctcctgc ataagaaaat caggatgtgt tcgatacagt tcagaatcaa
    20821 ccgagatcat ttcaggttca aaccataaac caaatttcaa tcctttgcta tgagcataat
    20881 ctgctatttc acgtaatcca tttgtcaact tgccttcata ctcgaaccag tctcctaatg
    20941 aagaattgtc cgcatctctt tttccaaacc agccatcatc taatacgaac atttcgatgc
    21001 ctagctcctt tgcttcatca atgatcgcct tgattttttc actattgaag tcaaagtaag
    21061 tggcttccca gttattgacc agaatcggcc gttcagcaaa ttgatgacga cctcttgcga
    21121 ttctttcacg tagcaactca tggtggatct gactcatttt gttcaatccc tgacttgagt
    21181 aagaaaggat catttcaggt gtttgaaaag actggcctgc attcaattcc cacgaaaaac
    21241 gatggctgtt gatcccaccg acgactctca attgattgat ctgatctttt tcaagttcga
    21301 aagaatggtt gccggaataa acaaattgaa gtccgatcgc ttctccagta ttttctgtcg
    21361 tatgatgatg aactaaagca ataaagttat tcatatggtg actgctcgtt cctcgacggc
    21421 tttcaaatac ttttgttcca gataaaacag attgccgtga aatctgtctt tcattgacat
    21481 gtgctcctgg caaagcaatg acttcatcaa atcgcctagt atgggcaaag tctagctgga
    21541 aactagccgc tttttctagt ttgattgttt ctccggtttc atttcttatc tttacagatc
    21601 gtgtgatcac tgctctatca gtaaatatgg tatagaacaa atcgaaataa atcgctgttt
    21661 ctctatcctt aagtgaaatc accaacgttt gtgcctctga cttgtccatc acataagttt
    21721 gaggcaagcc ttcgatctct ggcttcccat ctgtaatata atggctgtca tatctcagat
    21781 ccagtaagtc tgatccattc ttgcgctgaa tgatcgatgc gggcgttcga aagtccatgc
    21841 tgccatgaga agagtattct tgcggtagtg tatctttcga cagagaccgg tcaggattta
    21901 agggaacatt tcctgaaaat ccacgatctc ttcggggata atttttattg tctttgtact
    21961 gcttgactgg tttgccaaaa taaatatgcg ccaatacatt gctttcttct atctttatca
    22021 gataagaaag aaatgtattt cgtaaatgga agactcggct cttttcatca aataagatga
    22081 aatttttatc tgtttttcta tgcgtaatat ccatcatttc actcccaaca aaacggaaac
    22141 cgtttacttt tttttataat tcctgtatac tgtttactaa acaattttgt caataaaaat
    22201 tttttatttt tttgaggagt gtgtaaaaat ggttggaatt agagatgtcg cacgaaaggc
    22261 aaatgtctct cctgctacag tttcccgtgt gttgaataac gatcagacga tccatgtggc
    22321 tcagactact cggcaacgga tagtagaggc agctgctgcg ttggattatg acatcagtac
    22381 tcgtaaatat atcaaaaaga gaatgccttc gattggtgtg atctctacga tcggcaaagc
    22441 gagcgaagaa caggatatct attacaaaca tttgcgagta gggatggaag aagaagctcg
    22501 acgtctgcat ttagggatga atcgaatcta taatctatct gataatccta aacaatggga
    22561 agatctagat cagttaggtg cggtgatcgt tgttgggact gttacgaaag aatcgattac
    22621 cgccttgtta aaacaaaaca tgcaaatagt cgtcgtggat aaccctgaca tccagcaaga
    22681 ggtcgatatg gtgtatgcag atcttgaacg gatgactaaa accgtactgg aattgttctt
    22741 agaaaatggt cataaaagaa tagcctatat cgggggatat aaagtcgata tggatgaatt
    22801 cggtgggaag cagatttcta taaatgaaaa gaggatgcgt gcctatcagc attttatgat
    22861 cgatcatcac ttagaaaaat atatgtctta tcatctaggt ggctggacag aaaaacaagg
    22921 tgaggtactt gcgactaatc tattagaaaa tgaatcccct cttcctactg ccattcttgt
    22981 cgggagcgat ccaatggcaa ttggtgtcta tcgggcattg aaacaaaaaa atatccaaat
    23041 tggagaagag attgttgtag caagctttga taatatcgag acaatcgcaa acctctcccc
    23101 tggcttgacc agtgttcaaa tcaatgcgaa atcaattggg caagcagctg ttcgaatggc
    23161 attggagcga attgacggta tacgggacga accaatcatt ttgacttatc ctgcacgatt
    23221 gattgttagg gaaagtttta tcccaagaac aaaaaggtat tgaaagagag gttgtgaaaa
    23281 gccgcttcgt ttcttcatac tcaaaacgaa acggcttttt cacaacctct tacttatact
    23341 tattcacaaa atccaatgtc tgctggtaac aattttgcga ttcttttagc gtgtaatcaa
    23401 attggtattc atgggtaatc tctttttttg tatctgtata aaacaaggat tgcacgggta
    23461 cctttaattc tgtcaaccga ttttctaatg cttgaccttg ctcctggaat gagtatgcat
    23521 ttccgtcagt tatatacgtt ggcggaaatt ccttagaaac atggtcagcc acactagctt
    23581 ctttcaattg ctcactcgtt ttccaatctt ttgttccaat caacgaccac gcaacggttt
    23641 tgacgaaaaa cttcataaat cgatcatccg aatgctgctg tgctgttagc ttcaaatcaa
    23701 caggtccgca ataagaaatg gttcctttca gactatcttt tggaagtagc tgtttgattt
    23761 tcatttgttt agcatacgca tcattcgttt gtatagctgc atattgcaat gcgatttgtg
    23821 aacctgcact atctccacca aaaaataatt gttccatgtc tagcaatttg tcgtcttttt
    23881 cttcagctaa taaatctttg atcagttcat tcacttgaag aacttgatta gggtattctg
    23941 aatcaggcgc taattcataa ttcatcgcaa ccactgcgat gttggcgtct gaaactaatt
    24001 ttgtcgcaaa ttctttgaca cccgatttat ctccgccgac gaatcctcca ccatgtaccc
    24061 aaaatagaac aggaacaggc cccttgctgt tttttggata gtagatgtca taagtattct
    24121 ctttatactt ggactcatac gtcaaatctg tttttttcgc cacgtttttt tctgcttgat
    24181 cgaacgtttt tttatcagtg atttgaacag tatttgaaaa catatggttg atcaagaatg
    24241 ctccaggtct gggggaaagc tggaaggcaa gaaagattgc aaacgcgatc ccaagaatga
    24301 ttccgaagaa ccatccgata aatttaagaa ttttcttttt cataaggctc cctcagtagt
    24361 tagtattaag cattctgatt ataccatagt gttatttcct atcaagctct cctagatgat
    24421 ttaatgattt tccccaaact tcttctgcaa tgcttttgac aaaagaaatt ttttccattg
    24481 ttcttcaaac aaaacatttt cttcttctgt tgaagcaaat ccacattgag gacttaagca
    24541 caaacgatcc aaaggcagat atcgtgtcgc ttcgtagatc cggtcaatca cttgctggtg
    24601 ctcttccatt tcgccatttt tcgttacagt caaaatctaa gacaactaat ttatcttcag
    24661 agactttctc taaaagaaca aaactcccag cacgttcact atcgtattct aaataatagg
    24721 cacggacatt ttcttgagta aaataatggg tctgctacgt cgtcatcccc cctgatgccg
    24781 ccaaaatcga ataataattt ccgcgtcaaa catgtatatt tagtgttgaa tcatttgaga
    24841 atatgaaaat aaaaatcttt ttgatcaatc agttaatcaa attgaaataa cgaaaaatct
    24901 gagacagaat gacgttcatt ctgacccaga tttgattttg cacaactcaa cagtccttat
    24961 tggcaaatcg ccaaaataat gtagactaac taaaaagact aagaaacaat aacaaaagtt
    25021 aacacttctt agtctttctt tagcacgtct atttattaaa gattttaggg ccttttctca
    25081 tgtttttacg atcattctta ggtgtttcca tttgtttgga tcggcctcca ccttgtttct
    25141 ttttgatcaa ttctttcatt ttttcttttt ggtccatttt tattctcctt taacgaatga
    25201 agcgactaat tcgatatgat gggtttgcgg gaaaagatct acaggctgaa ctttcttcac
    25261 ggcataacct gcttctgcaa ataacttagc atctcttgca aaagttgccg gattacatga
    25321 gatatagacg attcgttctg gtgacatttc gattgctgat tcaataaaat gatgatctaa
    25381 tccttttcgt ggagggtcaa ctacgatcac agatggtttg atcccttttt cttgccattt
    25441 tttcataact ttttctgctt ttccgacttc ataatgaaca ttttcgattt tattatttaa
    25501 agcattgaac tgtgcatctt caattgcttc tggaataact tccatcccat acaccttatc
    25561 cactctgtct gctaaagaca agccaatcgt acctattcct gaataagcgt cgatcacaat
    25621 gtctttttta tctaactcgg caaactcgat ggctgtttgg tacagatact ctgcttgttg
    25681 agtatttact tgataaaatg actttgctga gattcgatag gtttttccta atagctgatc
    25741 ttcgatatag tctctgccat ataaaacttt ttctttgtct cctaaaatca catttgtttt
    25801 ttcttcattg atattttgga tgaccgaaac cacttctggc aattcttcat gaatagcttc
    25861 agcaatttcc ttggatttaa agaatttttc tttacgagta actaaaacga ccatcatttc
    25921 atgggaataa tgaccacgac ggataatgat gtgacgaagc tgtccttcat ttttttcttc
    25981 attatatcct cgtacttgga accgttgcaa gatatctctg actactttga ttgcttgatc
    26041 gatgacagga tcttggatat aaaaatcttc gatagggact agatcatggc tattcttttt
    26101 gtaaaaaccg gtggctaact gtccatcgat acggcgaaca gggatctgtg ctttattacg
    26161 gtagccgaat ggttctgcca ttccgaccgt tggaagtaca ggaacttctg gcatcttagc
    26221 aatcttcgcc attacatgct ctacttgttt ttgtttgaag acaagctgtt gttcatactt
    26281 caaatgggct aaaggtgcga tacctatgcg aagtaatgca ttgttttcta caggctgacg
    26341 atcaggtgat tgtgtaataa atgtttcgac ttttccatat ccaaacttat tgcctgcttt
    26401 tactactagt atttctactt cttctccagg gagtgcattt tcgataaata atggataacc
    26461 atcgattttt gctaccccca ttccttcata actcaagtcg acgatttcga ctgtatatcg
    26521 ttcgtttttc tttactattt gctgttctgt catattttgc tcctttaagc ctatttttca
    26581 atcctactga actctactat aaatcagcta attacacaac taaaaccggc actgacctta
    26641 ctacgttcag caccggcttt tgattaattc ttttgattag gtgtttcgtc tgctattttt
    26701 ccgtcaccgt cgatatcttc atccgttaaa cgttcgactt cttttacgaa ttctttgctg
    26761 acaacctcta attcttcttc atctgtacct gtgattgctt catcaggaat ctgatcggta
    26821 ttggcaaaga actcaatgtg ttgatgaaga ttttggaaat gcatcggtgc ttccccgccg
    26881 tattcaccat ctaagttgat cattactggt cgattgatat catcttctgt ttcaacgaac
    26941 aaactgcttg ttttggtata gattattctt ggatcatcga catgtcgacc gccattcagc
    27001 atgagtgctg caatatgcaa gatctcaaag atatttgctg tcttcacaat gattaaagaa
    27061 aacttcccat catccaattt ggcatctggc gcgatctgtt cgaatcctcc aacagagttc
    27121 gtcagcccta ggaaaaacat cgaagcattt ccgatatatt ccccttcatc atacttcaag
    27181 cgcattttga ttggctttac tcgagggagc atctctgctc ctttcgcaag ataagcaaga
    27241 taaccaaaaa tactctttag ttctgatgga acttcataag tcaattctgt caaatagcca
    27301 cctgcagcga tattgatgaa gtaactgtta tcagaaaggc cgatgtccat ttttacggtt
    27361 tggtgttttt ttatcacttc tgctgctgct ttaatattat ctctaggaat ttttaatgct
    27421 cgagcatagt cgttcgttgt accagctggg atgatggcca ttttaggacg gtgttcaagc
    27481 ggagcgattc cattaaccac ttcgttgatt gtgccatcgc caccagctgc cactactaga
    27541 tcaaaaccta gttctgcgac tctacatgct tcattcttgg ctgaatctgg ttctggtgta
    27601 gttgcatagg cgctggcttc aaatcctgct tcttctaatg cctgtaggat atccgccaaa
    27661 ttttttttca ataattcttt tcccgaggtg gggttataaa ttacgcgtgc ttttttcatt
    27721 ttcagcctct atcgtttcgc taattcatct ttaagtagct tattcacgac accaggattt
    27781 gcttgtcctt tagttgcttt catgatttga ccgactagga agccaaccgc acgatctttt
    27841 ccatttttga aatcatcgac agattgttgg ttgttatcca aaatttcatt aatgattggc
    27901 agtagtttgt tcggatcaga taattgcacc caaccatttt tttcaactac ttcttgggct
    27961 tctccgccat ttgtgatcaa ttcacggaag acttttttgg cgatttttga gctgatcgtt
    28021 ccatcggcga tcaaacgaat cattcctgct aagttctcag gtgtcaattt tgtctcagct
    28081 aattccagtt tctcactgtt caagtaagca gaaacttcac ccatcaacca gttagatgct
    28141 tgcttggcat ctgcaccatt ttccaaaaca gcttcaaaaa aatcagacat ttcttttgta
    28201 agtgtcaata ccattgcgtc atactctgga agtccaaact cacggatata gcgttcgcga
    28261 cgagaagctg gcatctcagg caaactagct tttacttttt gaatccattc gtcatcgatc
    28321 acgaatttcg ggatatcagg ctctgggaag taacgataat cactagaccc ttctttgaca
    28381 cgcatcaaaa ctgttttatt cgttgtttcg tcaaaacggc gtgtttcttg ttggatttct
    28441 cctcctgaaa gaagaacttt tgcttgacgt ttttcttcaa aagctaaacc ttttttcacg
    28501 aaagataaag agttcaagtt tttcaattct gctttcgtac cgaactcttc ttgtccataa
    28561 gggcgaagag aaatattggc atcacagcgc atagagcctt cttccatttt cacatcgctg
    28621 acttctgtaa attggataat tgatcgcaat gcttctagat aagcgtatgc ttcttctggt
    28681 gaacgcatat cagcttcaga aacgatttcg atcaaaggcg tgccttgtcg gttcaaatca
    28741 acgtaagaat aaccgccaat accatgcatg ttttttccag catcttcttc taaatggaca
    28801 cgttcgatcc ggattttttt ctttttacct tctacttcga tttcgatcca tccgtcatga
    28861 ccgattggtt gatcaaattg ggaaatttga tatgcttttg gattatctgg gtaaaagtaa
    28921 tttttccggt caaaatgagt atctttagag atttcacagt ttaatgccaa agctgctttc
    28981 atcccgaatt ccagcgcagc tttattcatt actggcagca cgcctggata accccagtcg
    29041 atcacgtttg tattgctgtt tggttctgca ccaaaatgag ctggcgctgg agagaaaatt
    29101 tttgagttgg tttttaactc gacgtggact tctagtccaa tgactgtttc aaaattcatt
    29161 cgtctttccc tcctaaaata gctggttgtt gtttatggaa ttctgttgct tgttcaaacg
    29221 catatgccgc ttgatacatc gttttttcat caaaataatt accgatgatc tgcaatccaa
    29281 ctggtaatcc ttctgataaa cctgccggta cagacatacc tggaagtcca gccaagttga
    29341 cagggatcgt taagatgtca ctcatgtaca ttgtgattgg atcgttaatg ttctcaccga
    29401 ttccgaatgc aactgttggt gaagatggcc cgatgatcaa gtcataatct gcaaagactt
    29461 tttcaaaatc tcgtttgatc aatgtacgga cttgtcctgc ttttttgaag taagcgtcat
    29521 aataacccgc gcttaaggag aatgtaccta acatgatacg gcgttttact tcttcaccga
    29581 atccttctga acgtgagttg acatatacat catctaatga tttcacattt tcagagcgat
    29641 aaccgtagcg gataccatcg aatcgttgca aattggaact tgcttctgat gaggcaatga
    29701 tataataaac agccacaccg tattttgaat gaggcaagct gacttcttcc acaacagcac
    29761 ctaatgaacg gaatgtttct gctgctttca atacagcttc ttttacgcca ggggccacac
    29821 cttcgcctaa gtattcttta ggtaaagcaa tcttcattcc tttgatgtcg cctgtcagtc
    29881 cctctgcaaa atcaggaact gaaacgcctg aagaagtacc gtctttttcg tcataaccgc
    29941 tgatagctgt caatgctaat gcattatctt tcaccgtacg ggtcattggt ccgatttggt
    30001 caagagatga agcaaaggca atcaaaccaa aacgtgagac acggccataa gtaggtttca
    30061 tccctacgat gccgttaaaa gctgctggtt ggcggatact tcccccagta tcactaccta
    30121 aagaaactgg aatttgtcca gctgcaactg ctgctgcaga accaccagaa gagccaccag
    30181 gtacttttgt tgggtcccaa gcattttttg ttttcttgaa ataagaagtt tctgtacttc
    30241 cacccatagc aaattcatcc atgtttagct taccaacagg gatcatatct gcttgataga
    30301 ttttatccat gaccgttgca tcataaattg gttcaaaatt gtaaaggatc ttagatgcag
    30361 cggttgtcaa gatatctttt gttacgatat tatccttgat accaattgga ataccagcaa
    30421 ggacgttgct ttcatcaatc cctttttcat ctaaagcttt tgcctgttcc aatgcttttt
    30481 cttcgttcaa tgtaatgaat gcctcgacct caggctctgt ttctttgatt cgttcaaatg
    30541 ttgtttttgt caaatcttgt acagtgattt ctttcgatac aagcatatga tgcagttctt
    30601 ctagagaacg attgtgtaat tctgtcatta tgcgccagcc tccccattat cgatgattgc
    30661 gggtactttg ataaagccgt cttctgtttc cggcacattt ttcaataatt catcgcggtt
    30721 ccatccagct tgcgcccgat cttgtcgcat cacgtttact gtttcaacca cattcgacgt
    30781 aaatggaaca ccttccgtat ctacttcttc cagcatttca accatatcga tgattttacc
    30841 taattggtcg gtaaaacttg caagttcttc atctgcgaac gcaagttttg ctaatttggc
    30901 aacgtgtttc acttgttctt cactaatcgc catactaccc cttctttcta aacgagttaa
    30961 aaactttgct ctctatttta acacaagagt gccgtgtctg aaattgttta ttgaaatttg
    31021 tctgaaaaaa ctcatttttc attcttctac tgagcgactt ttagccaatg catctgccat
    31081 ttgatcttct gtccaaactt cgattcctaa ttcttgtgct ttggtcagct tgctgccagc
    31141 atcttctcct gctaccacga tatccgtttt tttcgatacg ctaccagtca ctttcccgcc
    31201 aagattttcg atcgtctctt ttgcttcttc acgagtaaat cgtgttagtt taccagtaag
    31261 gactactgtt ttttctttaa aaggagactc gacttcttgc aattgggcat ttcgaagccc
    31321 tttgtattcg aaattgacgc ctgcttgttt taattcattc atcaattcat ggacttcttc
    31381 gttactgaaa taagtgacta cactgtcggc aatgatatca ccgatcgtat caagcgcaat
    31441 aatcgactca tagtcacttt tactcaatgt ttctagatca ccgaaatgtt ctgctaaaat
    31501 ttttgctgct ttcgctccga catgtcggat tcctaacccg aaaatcaacc gctcgaccga
    31561 attatctttg ctgttgtcga ttgctgtcaa aatattattt gctgattttt cttttatttt
    31621 gtccaacgtc aataactctt cttctgtcaa tttgtaaaga tcagcaacat ctgctactag
    31681 ttttttatca tacatctgtt ctagtacgcg cggccccaac ccatcgatat tcatcgcatt
    31741 tcttgaaaca aagtggttca aaccttcttt catttgagca gggcatttag gattgatgca
    31801 ccgtaaggct acttcttcat ccaaatggac aagttcactt ccacaaactg gacaatgtgt
    31861 aggcaattgg tattcttcgc tgtctttagg tcgtttatct aacacgactt gcgaaacttc
    31921 tgggatgatg tctcccgctt tataaatcag aactgtatct ttcaagcgga tatccttcaa
    31981 cttaatataa tcaccgttat gcaggctggc acggcttact gtcgttcctg ctactcggac
    32041 tggtgtcatg atagctgttg gcgttactac ccctgttcga ccgactgtcc attcgatgtt
    32101 ttcgattagc gtttcaactt cttctggcgg aaacttgtaa gctgctgccc atctcggtgc
    32161 tttgatagta aaaccaagtt gatcttgtag cgagaattca ttcactttga tgacgattcc
    32221 atcgatttca tagggcaaat ccacacgttt gtcatgatat tcttcaatgt atgaccacac
    32281 ttcatcaatc gaatgacata gacgtttttc ccgattcgtg tggaatccaa ttttttctag
    32341 ctcttctagc gcatcatact gggtttttgc ttgcatagga ccgaaatcag ctactgtgta
    32401 taaaaaagtg tccagatttc ttttcgctgt gattttagaa tctaactgac gcaaagaacc
    32461 agctgcggcg ttccgaggat tcgcaaagat atcttttccc tctgcttctc tgtcttggtt
    32521 caattggaca aatgaccgtt ttggcatgaa acattcgcct cttacttcga tgttcattgg
    32581 ttcttttaat ttgattggga ccgaccggac agtttttagg ttttcagtga tgttttctcc
    32641 tacagttcca tccccgcgag tcgcacctct cacgaaattt ccatcttcat aacgcaaaga
    32701 aacggaaagt ccatctattt ttagttcaca gcaatagtca actacacgtc ccactgcttt
    32761 ttgtacacgt tgatcaaaag ctatcagctc ttctttgctg aaaacgtcgt tcaaactgta
    32821 aagcggaata tcatgagtga ctttttcaaa accttctaat acttttccgc ctactcgttg
    32881 agtgggagaa tcagacgtga tcaaatcagg atattgttcc tcgattgcta ctaattctgc
    32941 gtattcttta tcataaacat agtcttccac tgttggttta tcttctacgt agtattcgcg
    33001 agaccattgg ttcagtcttg tacgaagttc ttctgctcgt ttagcagctt cgtcaatcgt
    33061 catttcatgt tccatcattt accctccact actaagcttt ttcaattggc gcaaaggcag
    33121 ccaaaagacg ttttactcct tgacttggga aagccacatc tagttctaga tccttcgacg
    33181 tcccgcttac tcggacgact gttcctagac cccatttttt gtgtttgact ttatctccag
    33241 gtttccagct gttattttcc cctccagtag cacttttaga gggaacaacc gctgtctctg
    33301 gctgtttata gctatatgct gtttttttag cgaatacagg cgttttttta ggcgtaggac
    33361 gcatgccttc gatttccagt aactcctgat cgatttcttc tacaaaacga gaaggtcggt
    33421 tatattgcgt ccgtccatat aatgttctgg agaaagcatt tgttaaatac aacgcttctt
    33481 ctgctcgcgt gatccccaca tatgcgagac ggcgttcttc ctccagttcg ctttcttcca
    33541 tcaatgctcg agataaagga aaaaccccct cttctagacc aatcaggaat acaactggaa
    33601 attctaatcc tttggctgca tgcaaagtca tcaatgtcac ttgggaagca tcttcttcta
    33661 aattgtcaat gtcggaaaca agtgccagat catttaagaa gaccgttagt ttttcttctg
    33721 gtgcatcagc gtcttcttca ttttgctgtt cgaattgttt gtcgaattct tgtgtgaccg
    33781 ttaaaaattc ctccaagttt tcgatgcgtg cttgtgcttc taatgtattt tggattttta
    33841 agtcttctag atatccgcta cgatccaaaa cctctttcgt caattctgtc actgtcaagt
    33901 atgggatcat ctgagtgact tcttggatca tctctccaaa tgcacctaat tgctgtcctg
    33961 cttttccacc gatatttgcc agatccacat tttgcgctgc ttcaagcagt ggccattcat
    34021 gaagagaagc aaaactgcgt agtttttcga tagatcctgg tccgatgcct cgtttgggcg
    34081 aattaacgat acgctcaaaa ctgattgaat cttgaggatt taccagcaca ttcaaatacg
    34141 ctaaaatatc tttgatttct ttacgatcgt agaacttgtg ccctccaacc attttataag
    34201 gaatatttgc tttcaacaga gtttcttcca ttacacgaga ttgtgcgttc gtccggtaca
    34261 agatggcaaa gtcgccgtaa ttccgatgat tgcttcgaat ctcttcttgc atccggtcta
    34321 cgataaaacg ggtttcgtct cgttcattat ctgcacggta gtaagtgatc ttgtttcctt
    34381 ctttgttttc tgtccacaag ttttttggtt ttcgattgct attgttttca atgacttggt
    34441 ttgctgcgct aaggatgttt ttcgtggagc gatagttttg ttctagcaaa attactgcag
    34501 catctggata atctttttca aaatccaaga tgttctgcat atctgcaccg cgccagccgt
    34561 aaatactttg atctgcatct cccacgacgc acaggttcct aaatctacct gccaataaat
    34621 tgactagcgt atactgtgcg tgatttgtat cttggtactc atctacatga atataatgga
    34681 atttgttttg ataatacgtg agtgaatcag gatgttcttc aaataatcga atcgtattca
    34741 tgatcaggtc gtcaaagtcc atacattgat tatattgaag ctctttttgg taagcagcat
    34801 aacattttgc cgcaatctct tcgtaataac tgccttgcat ttttgcaaaa tcctgagggg
    34861 tctgcaggct gttttttgct tgagagattg ttcctaatat acttcgagga tcatattttt
    34921 tcggatcaat gttcagttct tttagtatcc gtttcatcaa ggtcagctgt tcagaagaat
    34981 cgatgattgt aaagttccgg ttatacccga taaaatcaac atctcttctt aaaatacgca
    35041 cacacatcga gtgaaaagtc gatacccaga catcttcgcc tccagatgcg agaatcgcat
    35101 tgacacgttc tttcatttct tttgcagcct tattggtaaa agtaatcgct aggatgttcc
    35161 aaggattgac ttctttttcc tcaatcaaat aggcaatgcg gtgtgtcagc actctcgtct
    35221 ttccacttcc tgcacctgcc attagcagta atggtccgtc agtgtgaaga acagcttctt
    35281 tctgacgggg gttcatcccg tttaataatt cagctttgga tgacattaac aacatccttt
    35341 cttttatcaa tcttgttaat tatagcattt tcttggcttt cattaaacta gctagttcaa
    35401 aatcatttgt ttctttttat ggatttttcc ttgtcaattc gttgatttcg cgctaaatta
    35461 aaagaaagcg aggcgtttga atggaaaaaa aaggaaaaat caagaaatta gataagactc
    35521 agatatattt tattctaaaa ggaatatttg ttggactgct gacaggaatc gtcgttagcc
    35581 tgtttcgatt atctatcgaa aagctaagcg atttagttcg aagtatctat gaaatgagtc
    35641 gggaacagcc gatttactta attggcctag ctatttgctg catccttgca gcatttttcg
    35701 tgggttatct ggtcaaaaat gaaccggata tcaagggaag cgggattcca caagtagtgg
    35761 gacagcttcg cggggaatta tcaatgaact ggttctctgt tttatggaaa aagttcattg
    35821 gcggtgtact ttcagttggt gcgggccttt ttctaggtag agaaggacct tctatacagc
    35881 ttggcgcatc cattggacaa ggagctggac aattgtttcg gagtccatct tcagaagaaa
    35941 agattttaat ttctagcggt gcaagtagcg gacttgcagc agcattcaat gctcctatcg
    36001 caggattact ctttgtttta gaagaaatcc atcactcctt ttctccactt gtttggctga
    36061 catcatttgc ttcagcaatc actgctaact tcgtctctct ttactttttc ggcttgagac
    36121 ctgttttata tctaggtgac cttccttctt tgccgttgaa atattatggt tccttagtga
    36181 tcttaggagt acttctaggc atcttaggtt ttatttatca gaatgtcttg ctggctttgc
    36241 caaaatttta caaccgattg cctttaccag cttattttca cgggttcgtt cctttcttgc
    36301 tgattttgcc aattggttat ttatggccta gtactctagg cggaggcaat caaatcgttt
    36361 tagcttttgg acatgcttcc ttgccaatca ttatgattat cggtttgttt gttcttcgat
    36421 tcgttttttc catgatttct tacggtgggg gtcttccagg ggggattttc cttccgatat
    36481 tgacattggg ggctttaatc ggtagctttt atggaaacat tatggttgat ttcgggatgg
    36541 atccaatcta catcaaggat tttgtcgtta ttgccatggc tggttatttc acagcgattg
    36601 gaaaagcacc gctgacagca attattttag tgacagaaat ggttggctct cttaatcatc
    36661 tgatgccttt aggattggct gctcttgttg cttatatcgt caatgacctt ctcggcggta
    36721 atccaattta cgaatcatta ttggaacgtc tacttggaaa tactcagacc gcctcactaa
    36781 aaggtgcaag gacaactttt gattttccag taacggcaga gagttcttta gacggattaa
    36841 tggtacgaga cttcaattgg cctaaaaata tgctgctaat ctctatacgc agaggaaatc
    36901 aggaaatctt gactcacggt gatacgatca tgaatgtagg agatattttg gttatcttga
    36961 ctgatgaagc aaacttgcca agaatcaagc aggaaatcga ggctaaatct tctatcacaa
    37021 atttgaagca atcattttaa cgaacatgga aaaactattt tacaacaact attcatctac
    37081 actacttgat tctatatgat tctataaaaa aagaagaggc tgggaaaacc cagcct
//
LOCUS       DADLIO010000021        36230 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.021, whole genome shotgun sequence.
ACCESSION   DADLIO010000021 DADLIO010000000
VERSION     DADLIO010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36230
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.021"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            232..1500
                     /locus_tag="JOX41_001210"
     CDS             232..1500
                     /locus_tag="JOX41_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HAY6448967.1"
                     /translation="MGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKSVEEIPSPVT
                     GTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETSGSASVVEAA
                     DPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPSSAPAKSEAP
                     EAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVNSKHTAPHVT
                     LHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLNASIDDANQE
                     IVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDGKLSAEDMRN
                     GTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGRVMKLSLSFD
                     HRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            1508..2914
                     /gene="lpdA"
                     /locus_tag="JOX41_001211"
     CDS             1508..2914
                     /gene="lpdA"
                     /locus_tag="JOX41_001211"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HAY6448968.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            3076..3351
                     /locus_tag="JOX41_001212"
     CDS             3076..3351
                     /locus_tag="JOX41_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HAY6448969.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            3357..4124
                     /locus_tag="JOX41_001213"
     CDS             3357..4124
                     /locus_tag="JOX41_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HAY6448970.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            4292..6121
                     /gene="typA"
                     /locus_tag="JOX41_001214"
     CDS             4292..6121
                     /gene="typA"
                     /locus_tag="JOX41_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HAY6448971.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            6382..8154
                     /gene="recQ"
                     /locus_tag="JOX41_001215"
     CDS             6382..8154
                     /gene="recQ"
                     /locus_tag="JOX41_001215"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HAY6448972.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            8268..8570
                     /locus_tag="JOX41_001216"
     CDS             8268..8570
                     /locus_tag="JOX41_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HAY6448973.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            8573..9736
                     /locus_tag="JOX41_001217"
     CDS             8573..9736
                     /locus_tag="JOX41_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAY6448974.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            9762..13190
                     /locus_tag="JOX41_001218"
     CDS             9762..13190
                     /locus_tag="JOX41_001218"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HAY6448975.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            13211..14335
                     /locus_tag="JOX41_001219"
     CDS             13211..14335
                     /locus_tag="JOX41_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448976.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            14325..14762
                     /locus_tag="JOX41_001220"
     CDS             14325..14762
                     /locus_tag="JOX41_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HAY6448977.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            14746..15084
                     /locus_tag="JOX41_001221"
     CDS             14746..15084
                     /locus_tag="JOX41_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HAY6448978.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            15203..15763
                     /gene="rsmD"
                     /locus_tag="JOX41_001222"
     CDS             15203..15763
                     /gene="rsmD"
                     /locus_tag="JOX41_001222"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HAY6448979.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            15760..16251
                     /gene="coaD"
                     /locus_tag="JOX41_001223"
     CDS             15760..16251
                     /gene="coaD"
                     /locus_tag="JOX41_001223"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HAY6448980.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            16241..17284
                     /locus_tag="JOX41_001224"
     CDS             16241..17284
                     /locus_tag="JOX41_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HAY6448981.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            17443..18171
                     /locus_tag="JOX41_001225"
     CDS             17443..18171
                     /locus_tag="JOX41_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComEA"
                     /protein_id="HAY6448982.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            18287..18532
                     /locus_tag="JOX41_001226"
     CDS             18287..18532
                     /locus_tag="JOX41_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAY6448983.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            18529..18747
                     /locus_tag="JOX41_001227"
     CDS             18529..18747
                     /locus_tag="JOX41_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HAY6448984.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            18883..19422
                     /locus_tag="JOX41_001228"
     CDS             18883..19422
                     /locus_tag="JOX41_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HAY6448985.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            19415..21688
                     /locus_tag="JOX41_001229"
     CDS             19415..21688
                     /locus_tag="JOX41_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HAY6448986.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            21726..22772
                     /gene="holA"
                     /locus_tag="JOX41_001230"
     CDS             21726..22772
                     /gene="holA"
                     /locus_tag="JOX41_001230"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HAY6448987.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(22861..23115)
                     /locus_tag="JOX41_001231"
     CDS             complement(22861..23115)
                     /locus_tag="JOX41_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HAY6448988.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(23515..23784)
                     /locus_tag="JOX41_001232"
     CDS             complement(23515..23784)
                     /locus_tag="JOX41_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6448989.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(24254..24709)
                     /locus_tag="JOX41_001233"
     CDS             complement(24254..24709)
                     /locus_tag="JOX41_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HAY6448990.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(24847..26775)
                     /locus_tag="JOX41_001234"
     CDS             complement(24847..26775)
                     /locus_tag="JOX41_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HAY6448991.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(26972..27805)
                     /locus_tag="JOX41_001235"
     CDS             complement(26972..27805)
                     /locus_tag="JOX41_001235"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HAY6448992.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(27997..28701)
                     /locus_tag="JOX41_001236"
     CDS             complement(27997..28701)
                     /locus_tag="JOX41_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAY6448993.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(28724..29350)
                     /locus_tag="JOX41_001237"
     CDS             complement(28724..29350)
                     /locus_tag="JOX41_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAY6448994.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            29676..32051
                     /locus_tag="JOX41_001238"
     CDS             29676..32051
                     /locus_tag="JOX41_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HAY6448995.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(32075..32566)
                     /locus_tag="JOX41_001239"
     CDS             complement(32075..32566)
                     /locus_tag="JOX41_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HAY6448996.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            32753..33673
                     /locus_tag="JOX41_001240"
     CDS             32753..33673
                     /locus_tag="JOX41_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAY6448997.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            33827..34171
                     /locus_tag="JOX41_001241"
     CDS             33827..34171
                     /locus_tag="JOX41_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HAY6448998.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(34361..34861)
                     /locus_tag="JOX41_001242"
     CDS             complement(34361..34861)
                     /locus_tag="JOX41_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAY6448999.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            35389..35472
                     /locus_tag="JOX41_001243"
     tRNA            35389..35472
                     /locus_tag="JOX41_001243"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35423..35425,aa:Leu,seq:cag)
     gene            complement(35796..>36230)
                     /locus_tag="JOX41_001244"
     CDS             complement(35796..>36230)
                     /locus_tag="JOX41_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HAY6449000.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT        11989 a         6327 c         7491 g        10423 t
ORIGIN      
        1 ccgtcacctg ttacaggaac ggttaaaaat gtgattgttc cagaaggtac cgtagcaaat
       61 gttggggatg tattagtaga aatcgatgca ccaggacacg aagacaatga aggggacagt
      121 ggtgtagccg cagaatccca aactccagct aaaccggctg ctgaacccac tgttgataca
      181 gaatcagctg gatcgtcaag cgaaggagtc ttccaattta agttaccgga tatcggtgaa
      241 ggaatcgcag aaggtgaaat cgtcaaatgg ttcgtcaaac caggagatac gatcaatgaa
      301 gatgatacat tactagaagt tcaaaatgac aaatcagtag aagaaattcc gtcacctgtc
      361 acagggacag ttaaaaacgt gattgttcca gaaggcactg tagcaaatgt tggggatgta
      421 ttagtagaaa tcgatgctcc tggacacaat agtgcaccgt caactagtgc gccatcagct
      481 gaagcaccaa aagaaaaagt ggaaacatca ggttcagcaa gtgtcgttga agctgccgat
      541 ccaaataaac gtgtattggc tatgccatct gttcgtcaat ttgcccgtga aaaagatgta
      601 gatatctcac aagtaactgc aactggaaaa ggtggcagag taacaaaaga ggacatcgaa
      661 aacttcttgg caggtggtcc aagcagtgca ccagcgaaat cagaagcgcc agaagcggca
      721 gcaccgaaag aagcagctcc tgcagcagaa agcaaaccag ctgcaccagc aaaaccattc
      781 aagtccaact taggagactt ggaagaacgt gtagcaatga cgccaacacg taaagctatc
      841 gctaaagcaa tggtcaacag taagcataca gctccacacg tgacattgca tgatgaagta
      901 gaagtgtcta aactatggga taatcggaaa cgatttaaag aagttgctgc tgcaaatggt
      961 acgaaactta ctttcttgcc atatgtcgtg aaagctttaa cagcgactgt taagaaatac
     1021 ccagtattga atgcatctat cgacgatgca aaccaagaaa tcgtttataa acattactac
     1081 aatatcggta ttgcaactga tacggatcac ggactatatg taccaaatgt gaaagatgca
     1141 gaccgcaaag gaatgtttgc tattgcagac gaaatcaatg agaaagcaaa attagctcat
     1201 gacggcaaac tatctgcaga agatatgcgc aatggaacaa ttacgatcag caatatcgga
     1261 tctgtaggtg gcggttggtt tacaccagtc atcaactatc cagaagtagc tattttaggt
     1321 gtaggaacga ttgcacaaca accaatcgta aatgctgaag gcgaaatcgt tgtcggtcgt
     1381 gtgatgaaac tgtcattaag tttcgatcac cgtatcgtag atggagcaac tgcgcaacaa
     1441 gcaatgaata atatcaaacg tcttttagct gatccagagc tattaatgat ggaaggatga
     1501 taaacaaatg gtagttggag attttgctgt agaattagat acagttgtaa ttggtgcggg
     1561 acctggtggc tatgtagctg ccatccgcgc tgctgaaatg ggacaaaaag tagcaatcat
     1621 tgaaagagag tatattggcg gtgtttgttt gaatgtcggc tgtattcctt caaaagcact
     1681 gatagctgca ggacaccatt atcaagagtc actagattct gaaatgtttg gagtaactag
     1741 tgaaaacgtc aaactagatt ttgcaaaaac acaagaatgg aaagaaaaca aagttgtcca
     1801 tacgttgact tctggtgttg gtttcctatt aaaaaaacat aaggttgaaa caatcgaagg
     1861 agaagcgttc ttcgtagatg atcacacact acgcgtcatt catccagatt cagctcaaac
     1921 ttattcgttc aataacgcaa tcatcgcaac aggttcccgt ccaatcgaga ttccaggatt
     1981 taaattcgga ggacgtgtgt tagattctac tggcggatta gcattgaaag aagtacctaa
     2041 gaaatttgtg atcatcggtg gcggtgtgat tggtgccgaa ttgggcggag cgtacgcaaa
     2101 cttaggagca gaagtaacga ttcttgaagg ctcaccacaa attttaccaa cttacgaaaa
     2161 agatctagta aaattagtag aagatgattt caagaaaaaa ggcgtaacag tcgtaacgaa
     2221 tgcaatggcg aaagaagcag tcgataacgg tgacagcgtg acagtgaaat atgcagtgga
     2281 cgggaaagaa gaatccgtta ctgctgatta tgtgatggtc actgtaggtc gtcgtccgaa
     2341 tacagatgat atgggcttag aacaagcggg tgtcgaagta ggagaacgag gattgatcac
     2401 ggtggataaa caaggacgta cgaacgtacc taacatctat gccatcggtg atatcgttcc
     2461 aggggcggca ttagcacaca aagccagtta tgaagcaaaa atcgctgctg aagcaatctc
     2521 tggcaaaaaa gtagctgtag attataaagc aatgccggca gtagccttca ctgatcctga
     2581 attggcttct gtaggtatga cgatcaaaga agcaaaagat gctggtatcg aagcaaaagc
     2641 atataaattc ccattttcag ggaacggtcg ggcattatcg cttggtaaaa cagaaggatt
     2701 catccgtcta gttacgacga tcgaagataa cgtgcttatt ggcgcgcaaa tcggtggagt
     2761 cggcgcaagt gatatggtct ctgaattagc tttagcaatc gaatcaggaa tgaatgctga
     2821 agatatcgcc ttgacgattc atcctcatcc atctcttggc gaaatcgtca tggatgcttc
     2881 ggaattagca ttaggtttac caatccatat ttgatttgaa taatacaggc gaaacgcaac
     2941 tgaaaaatca gttgcgtttt gttttttaga attatcaata atattattat gtaaacttaa
     3001 aaatatgaca acttcttggt ttattaccac ttcctatgct acactgaaga ggaatatgaa
     3061 ataggagagt tgaagatgca agaatatcag tatccacttg atttagattg gacaacagac
     3121 gaaatggtca ttgtaatgaa gatgtgggaa gatctggaac gtgcgaatga aaaagggata
     3181 aacaatgaag cttttttgaa gacttatcag cagtttaaaa ctgttgtcaa atccattggt
     3241 gaggaaaaac gattgggacg ggaatttgaa aaagcttccg gttattcttt atatcgtaca
     3301 gtgcagcaag caaaaaaaaa tccaaacaaa actttgagaa tgaacgggtg agataaatgg
     3361 aacagatgat tgatcatatc aagtcctggc ttgaagaagc tggtgagaaa atcaaatctt
     3421 ctcaacaaac attaacaatc tcgcaaaaat caaatcgaac ggatctagta acaaatgtcg
     3481 atcgaaacat ccagaatttt ctaatcgaaa aaatccattc ctttgatcca gaggcgaaaa
     3541 tattggcaga agaagaaggg tgtaatcaat tatcggatct cgatggaaga gtctttatca
     3601 tcgatcctat tgatggcacc ttgaattttg tgattgaagg ggaaaatttt tgtattatgc
     3661 tcgctgttta tgaatccggc gttggaaagc ttggtttcat ttatgacgtg atgagaaatg
     3721 aacttttttg gggtggaaaa ggaataggcg tgtataaaaa tgatgagcca ttgcctagac
     3781 cagcaaataa atccttatcg gaaggcttac ttggtgtgaa tagttatctt ttcggtcata
     3841 ataaatatgg aatccgagaa attgcggaaa gcagcatggg gacacgtatg tacggatgcg
     3901 ctggtcttga actagtggca atcttgaaag gaaaccacat tgcttatatt tcaaacctta
     3961 gcccttggga ttatgcagcg ggaaatgtct tattggaaga gtttggtatg gtaacaagcg
     4021 gtctttttgg tactcctttg acatttgaaa aaagggaata ctatttagca gggacttctt
     4081 gtgcatatgc agaaatcgca gaccttttga aaaaagaagg ctgaaaaaaa ggtagaaatc
     4141 attcacaaaa atgataaaaa cgagcaaaag attaattttc tcgaaaaaat gaaaacattt
     4201 tactatattt catgaaaaaa gtctgctata attagcagtc gagtaaaatt tgccctgtca
     4261 taaagaacca ataaaaaagg agttagttac attgaattat agaaacgata tccgtaacgt
     4321 cgcaattatt gcccacgttg accacggaaa aacaacatta gttgatgaac tattaaaaca
     4381 atcagataca ttagacgcac atacgcaatt gcaagaacgt gcgatggact caaatgcgct
     4441 agaaaaagaa cgtggtatca cgattttagc caaaaacaca gctgtagact ataaaggtat
     4501 tcgcgtaaac atcatggata ctccaggaca cgcggacttc ggtggcgaag tagaacggat
     4561 catgaaaatg gttgacggcg ttgtgttggt cgtagatgcg tatgaaggaa caatgcctca
     4621 aacacgtttt gtattgaaaa aagcactgga acaacatatc acaccaatcg ttgtcgtaaa
     4681 caagattgac aaaccttctg ctcgtcctga gcatgtcgta gatgaagttc ttgaactatt
     4741 catcgaatta ggagcagatg atgatcagtt agactttcct gtgatttatg catctgcact
     4801 aaatggtacg tcaagcttgt cagatgatcc agcagatcaa gaaccaacca tggcacctat
     4861 ttttgataca attattgaaa aaatccctgc tcctgtcgat aacagcgacg aaccattaca
     4921 attccaagtt tcattacttg actacaacga ttatgtaggt cgtatcggaa tcggacgtgt
     4981 atttagagga acaatcaaag taggagacca agtagcatta attaaattag acggaacagt
     5041 taagaaattc cgtgtaacga aattatttgg tttctttgga ctaaaacgtc tagagattca
     5101 agaagcaaaa gctggagact tgattgctgt ctcaggtatg gaagatatct ttgtcggtga
     5161 aacagttact cctgtggatc atcaagatgc gttacctatc cttcacattg acgaaccaac
     5221 attgcaaatg actttcttag ttaataattc accatttgcc ggtcgagaag gtaaattcgt
     5281 aaccgctcgt aagattgaag aacgtttgat ggcagaactt caaacagatg tatccttacg
     5341 agttgaacca acaaactctc cagatgcatg gacagtttct ggtcgtggag aattgcattt
     5401 gtctatcttg attgaaaaca tgcgccgtga gggatacgaa ttgcaagtat ctcgtccaga
     5461 agttattgaa aaagaaatcg acggtgtaaa atgcgaaccg tttgaacgcg tgcaaatcga
     5521 tacaccagaa gaatatatgg gtagtgttat cgagtccttg agcttacgta aaggtgaaat
     5581 gcaagatatg gtccatacag gaaacggaca aatccgtttg acattcttaa cacctgcccg
     5641 cggtttgatt ggttattcaa ctgaattcct ttcaatgaca cgtggttacg gaatcatgaa
     5701 ccatactttt gaccaatatc tgccaatgct tcctggtcaa attggcggac gtcaccaagg
     5761 ggcgcttgtt tcgatcgata caggaaaagc aacgacttat tctatcatga gtatcgaaga
     5821 acgcggtaca gtcttcgtag aaccaggtac agaagtatat gaaggaatga ttatcgggga
     5881 aaacagccgt gataatgatt tgactgtcaa catcacgaaa gcaaaacaaa tgacaaacgt
     5941 acggtctgct actaaagacc aaacatctgt catcaaaaaa ccaaaacaat tgacgttgga
     6001 agaatctttg gaattcttga atgatgatga atattgcgaa gtaacaccag aaagcattcg
     6061 cttgagaaaa caaattttag agaaaaatgc tcgtgaaaaa gcatctaaaa agaaaaaata
     6121 atctgtaaaa ggatgaagag agaaaccagc ttgttataaa aaatagctgg tttctttttt
     6181 tgtccaactc ttttctgtgg agaagtcatc tttgtcaatg gacataaatt cagaaaatac
     6241 gccgaaagac gtttaaaaga cttttaaaaa acttatttct agagagtttt tgtttcataa
     6301 taagataatg tttcacgaaa ggagatcaac ttgtccttcg aagaaaatcg aagtaaaatg
     6361 gcaagagaaa ggagcgggaa gatgaacgac ttattaaaac aatactttgg ctatgatgag
     6421 tttagacctg gtcaaaaaga aattatccag aaagtcattg atcaggaaaa tgtattagga
     6481 atcatgccta ccggaagtgg gaaatcaatc tgttaccagc ttccagcttt actattagat
     6541 gggcttactg tggttgtgtc ccctttaatc tctttgatga aggatcaggt ggacgcggcg
     6601 aatcaattag gtatacccgc cacttttatc aatagctcgt tagatggtta cgaaacagct
     6661 agacgcttcc aagaaatcga tagacagcag taccgtttac tttatatcgc tcctgaacgt
     6721 tttatcatgc cggattttat ccaagcaatg aagcgatgga acgtccgtat gatcgctatt
     6781 gacgaggcac attgtatctc tcagtggggg catgatttcc gcccaagtta tttacagatg
     6841 gcgaaccagc tagatcaact gccaaatcgt cctgtaattg ttgctttgac agctacagcg
     6901 actgtgcaag tagctgctga cataaaaaga cttttaaaaa ttccagaaaa caaccatatt
     6961 cagactggtt ttgaacgaga aaatctacga tttcaagtaa ttaaagatca aaaaaaagaa
     7021 caatatctaa tcgaatattt aaagatcaac aaaaatcaat ctggtatcat ttatgcagca
     7081 acgagaaaag aagtagaccg tctctatcat ttgcttaaaa aattcgattt ttccgtgggt
     7141 agatatcatg gtggtctaaa tgagaatgag cgaacagaaa tgcaagaagc ctttttatac
     7201 gatcgcttgc agctgattgt agcgacaaat gcatttggta tgggtataaa taaaagcaat
     7261 gtccgttttg ttatccatta tcaaattcct ggctctctag aagcatacta tcaggaagct
     7321 ggtcgggcgg gaagagatgg tctttccagt gaagccatcc tgcttttctc tcctcaagat
     7381 atccaagtcc aaaagttttt tatccagcag tcccaaagag aagaagggca aaagcaaaaa
     7441 gaatatgaaa aattaaaagc gatgacagaa tacgtgtata ttgagtcctg tcttcagcaa
     7501 tacatcctaa actattttgg cgagacaagc agtccgtgca accgttgtgg taactgttta
     7561 gatgacagag aaatagtaga agtaacgaca gaagcacaga tggttctttc ttgcttaaaa
     7621 cgtatgggtg agaactatgg taaacaaatg ctgatgaaag tcttagcagg atcgaaagaa
     7681 caaaagctgc aagctttagg ttttggacat ttatctacct atggactgat gaaaaaccaa
     7741 tcgcaaaaag aaacgatgca gttaattgaa tatttgatat cgaatggcta tcttctgacc
     7801 atcaatggtg agtatcctgt tttgaaagta acagaaagag ggatacaagt attgaaagga
     7861 caagaatctg tttatcgaaa ggaacccaag aaagtccagc agctatcgga tgaagaaacc
     7921 gatacactat ttgaagtgct gcgggaactg cgaacggatc tagcatcaga agcaggcgtt
     7981 cccccgtatg tcgtattttc agattccaca ttgaaagaaa tgagccgaat acgtccatca
     8041 agcagattgg agatgcttca gataaaagga gttggccaaa gcaagcttga taaatatggc
     8101 gaagcctttt tatctcggat aaaaaatgcg gactctaacg ttctggataa gtagaaagaa
     8161 cgaatacgta aaaatgaata aaaacaactg gttaaatctg ttttttttgc tccttatgaa
     8221 aatcaaatat gttataatta aggaattaga atgggaggta agcacagatg gattctttgt
     8281 cgaaaaaact tgcgatccaa gtattaaatg atgaagcaga acggatcaaa cgattaatcc
     8341 gaaatcaaaa caacagtctc tgtatctcac aatgcaaagc cttcgaagaa gtggtagata
     8401 cacagatgta cggcttttcc cggcaagtcg gttttgctgt ccgtatagga gtaatcggaa
     8461 agaacgaggg ccagctgatg ttaagtgagc tagaacgaga attgaatcag ttatatagtg
     8521 aggtttacca agaaatttat gataaaaaag aagttggcaa ggaggaatag acttgcctaa
     8581 gaaagtgaaa aaaaggcatc tattagacta tagcatcttg attccctatt taattttatg
     8641 tgtattggga ttgatcatgg tatatagttc tacgtcgtat ctattattag aaaacggaca
     8701 aaatccgtcc gcatcagtca ttaaccagag tattttttgg gtgcttagct tgattgctat
     8761 cgcactactt tataaaatga aaacagatgt tttgaaaaac cagcgtttga tcatggcagc
     8821 catcgcagtt ttgacgattt tgctgctgat tgttgtgttt tttggtaagg agatcaatgg
     8881 ggcgaaaggt tggctgcaaa ttgcaggatt ctcgatccaa cctgccgaat acctaaaaat
     8941 catttctatc tggtacctgt ctctgacttt atctaaaaga caaaacagtg tacaaaaaga
     9001 ttttcttggg actgtgaaac gtccacttgc aatggttatc ggacttactg cattagtcgc
     9061 tattcttccc gattttggta atgcggcagt tatctttttg attattttgg ttctgctttt
     9121 agccagcgga gtcaattatg tgtatacttt gattgtagga gtaggaggct tttgtctaag
     9181 tacttttacg atctggctga tcaatatcac aaacggaaag atcttacccg gacgtttaca
     9241 gtatatctat aatcgatttg ctatttacca aaatcctttc tcagacgaat taaataaagg
     9301 gcatcaacta gtcaacggct actatgccat gttcaacgga ggactatttg gcaggggatt
     9361 aggtaacagt atccagaaaa aaggattttt acaagaagca caaaccgatt ttatttatgc
     9421 aatcgtagtg gaagaactgg gagtgattat ggggattttg atattagcgt tgctattctt
     9481 tatgattgtg cgcattgtcc ttgtaggtat ccgttcaaaa gatccgttca attcgctttt
     9541 gtgcattggg atcggcgcaa tgtttttgat ccaagtattt gtcaatcttg gaggaattac
     9601 tggcgttatt cctttgacag ggatcacgtt cccattttta agtcaaggag gctccagttt
     9661 gctgatgctt tcgatttgtg tcggctttgt cctcaacatc agtgcggatg aaaaacgcaa
     9721 gagcttaggt ttataataaa aaaagatgta ggagtggttc gatgaaaaaa gttttagttg
     9781 ctaacagggg tgaaatcgct gtacgtgtat ttcgtgcttg tacagaatta ggaattaaaa
     9841 ctgttggaat ctatgcagaa gaagatgaat attccgtaca ccgtttcaaa gcggatgaag
     9901 catatttagt aggacaagga aaaaaaccga ttgatgcgta tctagatatt gaagggatca
     9961 tttctatcgc gaaagaatgc ggagctgacg ctattcatcc gggttacggt cttttgtcgg
    10021 aaaacttgaa ttttgcgcaa cggtgcgaag aagaaggcat catttttgtt ggacccaaac
    10081 tgcatcattt agatattttt ggagataaaa tcaaagcaaa agctgcagct atcgaagcgg
    10141 ggattgcttc gattccaggc acagatggac caatcgcttc tatagacgat gccttggagt
    10201 ttgcgaaaca atacggttat ccgattatga tcaaggcagc tctaggcggc ggcggacgcg
    10261 gcatgcgtgt agctcacgat gaaaagagtg caagagaggg ctacgaacgt gcgaaaagcg
    10321 aagcaaaagc agcctttggt agtgatgaag tgtatgttga aaaatacatc gctaatccta
    10381 agcatatcga agtacagatt ctcggggata cgcatggaaa cgtcatccat ctttttgaaa
    10441 gagattgttc tgttcagcgc cgtcaccaaa aagtagtaga agtagcgcct tgtgtctcta
    10501 tgaatgaaca gcaacgtcaa aaaatctgcc aggcagctgt ccaattgatg aaatatgtcg
    10561 ggtatgtcaa cgcaggtaca gtagaatttc ttgttgaagg agatgatttt tactttatcg
    10621 aagtcaaccc tcgcgtccaa gtggaacata cgatcacaga aatgattaca gatattgata
    10681 tcgtaacaac gcaactgttg attgctcaag gtttggatct gcataaagaa atcggattgc
    10741 ctcagcaaga aggaattaaa ttaaatggtt cagccattca atgccgaatc actacagaag
    10801 acccgttgaa taacttttta ccagacacag ggaaaatcga tacgtatcgt tcacctggtg
    10861 gttttggcgt acgtctggat gtcggaaatg cttacgcggg ctatgtagtg acaccgtatt
    10921 ttgattcatt gctagtaaaa gtatgtacgc atggtgctac ctttgaaaca gccattcaga
    10981 aaatggaacg ttgcttgaaa gaatttagaa tccgtggagt gaaaacaaac attccattta
    11041 tgctcaatgt catcacacat cctgaattcc aatcaggaaa tgcaaaaaca accttcattg
    11101 atagtacagc aacattattt gaatttcctc gactacgaga ccgcggaaac aaaacgatga
    11161 aatatatcgg tgaaattact gtgaatggtt ttccaggtat cgaaagtggc gaaaaaccat
    11221 tttatgaaga accacgtatg cctaaagatc taatcacaag aactgattac gtaacggcta
    11281 agaatgtatt agatgcgaag ggtgccgatg ctttggtcga atggatcaaa ggacaggaaa
    11341 atttgttgtt gacggatacg acatttagag acgcccatca aagtctgcta gcaactcgtg
    11401 ttcggacaaa ggatttcaag cagattgcac gtttgactgg agaaggtctt cctgaactct
    11461 tttcaagtga gatgtggggg ggagcaacat ttgatgtggc ttaccgcttt ttgaatgaag
    11521 atccttggca acggttgaga aaaattcgtt ctttaatgcc taatacgttg ctgcaaatgc
    11581 ttttcagagg ttcaaatgcc gttgggtatt ctaattatcc tgacaatgta ttggtggaat
    11641 ttgtcaaaga agcagcagcg caaggaatcg atgtatttcg aatctttgat agtttgaact
    11701 ggactccaca aatggaaaaa agtatccaag ctgtacggga tactggtaaa atcgcagagg
    11761 cagctatttg ctatactggc gatatcaacg atccaagtcg ggcaaaatac aatgttcagt
    11821 attataaaga catggcaaag gaactagaac aactgggtgc gcatatcatt gcaatcaaag
    11881 atatggctgg gctgcttaaa ccgcaggcag cttatcgttt gattagtgaa ttgaaagaaa
    11941 cgacagatct gccaatccat ctgcatactc atgataccag cgggaatgga atcatcactt
    12001 attctgctgc ttcaaaagca ggagtagaca tcgttgacgt ggcaatgagt gcaatgagtg
    12061 ggaatactag tcagcctagc atgagcagct tgtattatgc actggtcaat ggtccacggc
    12121 tgccagaaat cacgattgaa aatgcacaga aattaaacca ttattgggaa gatgtgcgca
    12181 tgtattacaa accgtttgaa aacggcttga atgctcctga aacagaagta tatatgcatg
    12241 aaatgccagg aggacagtat tcgaatctac agcaacaggc aaaagctgtc ggattaggtc
    12301 atcgctggga tgaaatcaaa caaatgtatc atactgtcaa cttgatgttt ggcgatatcg
    12361 ttaaagtaac tccatcatct aaagtagttg gagatatggc actatttatg gtccaaaatg
    12421 atcttacaga agaagatatt tatgaaaaag gcgaaacact aagtttccct gaatctgttg
    12481 tgactttctt ccaaggagaa ctagggcaac ccgttggcgg atttcctaaa aaattgcaaa
    12541 agattattct taaaggcaga cctgcattga atgaacgtcc aggtcttttg gctgaatcag
    12601 tcgacttcaa cgaagtaaaa aaagaattgg cagaaaaaat tggctatgaa ccaaaacaag
    12661 acgaagtatt aagctatttg atgtatccgc aagtcttttt ggactatcaa aaagcatata
    12721 atcaatttgg cgatgttaca ttactggaca caccaacatt tttccaaggt atacgtttgg
    12781 gtgaaacaat caatgtacaa atcgaacgcg gaaaaacgct tatcattcgt ttagatgaaa
    12841 tcggagaacc cgatatcgaa gggaatcgcg tactgttctt caatttgaat ggacaaagac
    12901 gtgaaatcac tatcaaagat aattcgatca tcagtacggt ccaaacccga ttgaaagctg
    12961 aaccgacaaa ccgagaacaa attggagcaa cgatgtctgg ttctgttttg gatgtattag
    13021 tgaaaaaagg cgataacgtt aaaaaaggtg atacgttgat gattactgaa gcgatgaaaa
    13081 tggaaacggc catcgaagca cgttttgacg gagaagtcgc acatgtatat gtgtcttcag
    13141 gagacactat ttcgtctggt gaccttttga ttgaagtgac tgagaaataa taagcgaaag
    13201 gtggggaaac atgaaaagac tgggtttgtt ttggctgatt ctgctattag ttattgtggc
    13261 attctacatg gaaccagtct tgtttccgcc aaaacttgaa gtgaaggaaa actctgatca
    13321 acaaatatca aaccaaatga caacgtggaa ataccaggag cttaaagcaa ctggtttttc
    13381 tacttatatc ggaaaaccga tcgatcagct ggaaaaggat tttggccaag cctatgatcg
    13441 attaactagc ggatttggtt ttgaaacaag atattatgaa aataaagcta gtcatctcac
    13501 atttgaagcg aacatccaag acagcagagt cacaactgtt aaagtactgc aaacagggcc
    13561 tgctgatatc gcgccgtttt atttagggat gacgatgcaa gatcttacga aaatcactac
    13621 tatctatact aatttcactt ttgagtacca tgatacagaa gttggaatcg aactaatgga
    13681 agaggatatg aattatcgtc cgctaattgc ttttgataac gacacttttg ctattttatt
    13741 ttttgatcaa acaacaaacg gcctattttc agttgtgtat ttagataaag atagtctttt
    13801 gaaactattg ccatatcaag tgtttggtga aggccttcca cattatcaag cagataaatc
    13861 ggctgattgg gaatcaatca atcgcgttaa agaacgaaaa agtacgactt tattaaatat
    13921 gcttagaaga gaagacgaac ttcccatata caatcaaaca cttgcctttc aaaaccacag
    13981 tcagctgcta ctacatgatt ttttgacaag gcctgaggaa atattgtcag aggaacgtat
    14041 ggctgattgg caaaaatcgc taggcagtgc tcaaacgaca gtgaaattct cactgacgaa
    14101 tgatgaattg gagaagttaa tcagtaaaca aaaattagaa aatactagtg ggctatttat
    14161 tcatccggcg attgacgcta ctttttcgtt tttatattgg tacagcgatc cttacaacca
    14221 tgaccgtttc atggacccgg gaacggattc tgtaggcatt gctttttcta aagaaaatat
    14281 gttagtctta ttgcaagaag aaaacggaga aagtagtgat agcagtgatc gttaacgaag
    14341 agctgtttca actggaggat caatgcctcc aagtcgctga aatgataaaa aagagtaaaa
    14401 cgatggcttc ttatcttgaa cataaacagt caatggaaga atctgcaaaa gtttgccagt
    14461 tgaaagaagc gttcttgtct aagaaagaag catttgaaaa tgtagcggca tatggtgagt
    14521 atgcacctga ttatcgtgaa aaaaaacgag ctgttcgaaa agcaaaaaga cagcttgata
    14581 tggatgagca tgttgcagct ttccgatata gtgaaacaca gctgcaaagt ctgttggatc
    14641 aaattgtcca agtacttgcc gaagaagttt ctaatgaaat caaagtagat gcaggtagcc
    14701 cgttttttga aacgaaaaaa cactttggat gcggaggtaa ttgtcatgca attagacaat
    14761 agtgaatttg aaataacaaa acgacgcggg ctgatcgtat gggtctacag cttaaaacaa
    14821 ttaaagaatc tgaaaaagtt cggcttgttg cattatgtct caagaagaat gaaatatgtc
    14881 gtgctttact taaatgaaga gacattggaa gaaacagaag aacgaatccg taaattacat
    14941 tttgttcgaa acgtagaacg ttcttaccga ccggatatcg aaatgaattt tgccgaaaaa
    15001 ataggaaaca aaacagtatt aaaagacgaa ggtttcgaaa ttgaagagct aaatacagaa
    15061 atccgattag ctgaacatct ttaaaaatct cttatgagca gtttttaaat aaaaaataac
    15121 ttggataacg atcgattttt gatcattgtc caagtatttt tttggtatac tagtaccagt
    15181 accatttcta aggagtgagt agatgcggat aatatcagga aattatggcg ggcgccgttt
    15241 aaaaagttta gcaggggcga acaccagacc aactacagat aaagtaaaag aatccatatt
    15301 caatatgatt ggaccatatt ttgatggaga gacagtattg gatctgtttg caggaagcgg
    15361 tggtttagct atcgaagcag tatctagagg ctgcagtcat gcggtatgcg tagacaaaaa
    15421 ttaccaagcg ctaaaaatca tcaaagaaaa catcgaaatt acgaaagaac cagagaaatt
    15481 taccacaata aaacttgatg cggacaaagc aatcgaacgg ctagcagcgg agaaacaaca
    15541 attcgactac ttgtttcttg atccgccata tgcaaaacaa aaaataatcg atcaaatcca
    15601 taaaatggaa gaactgggac ttttttctaa aaccgcagtt atcgtatgcg aaacggataa
    15661 aacagtcgaa ttgccagaaa ctgtggctgg attccatcaa ataagaaaac agatttatgg
    15721 cataacggcc gtaactatct atagaaaaga gggaaatcaa tgaaacgtgc attattccca
    15781 ggaagttttg atccttttac aaaaggtcac ttagatacgg tggaacgtgc ggctaaatta
    15841 ttcgatgagg tagtaattgg tgtttttatc aatacttcaa agaaaagttt gtttccccca
    15901 gaagaaagaa tgacattgat cacaaaagct gtttctcatc ttcctaatgt aaaagtcatg
    15961 catcaagaaa atcaattgac ggtagaaaca gcaaaagaga ttggtgcaga tgcgttgatc
    16021 agaggcatac gaagtatcaa agactttgaa tatgaacgag agattgctca gatgaatcat
    16081 catctatatg atgaattgga aactgtcttc ttattagcaa aaccagaata tagtcacgtg
    16141 agttccagta ttttaaaaga agtactgcac tttggcggag atgtgagcag ctacttaccg
    16201 ccagtgatca acgaagcttt agctggaaag cgtgaatcaa atgaaagcta aacaatggtt
    16261 gaaaacagta ctgattatca tatttggaat gttgatcatt ggatttgtag tagttccctt
    16321 gccgtattat gtagaatcac cgggagccac gatcgatctg aaagaactaa ttacggtcaa
    16381 tgataaggaa gataaaggtt ctgggtcttt ctctcttacc tctgttggta tcaggcaagc
    16441 tacaggtttc ttagctttaa aagctaaaat gacccctttt gaagaattga tcagtgaaga
    16501 agaattgact ggtggggcga caaatgaaga atataatcaa atgcaacagt attatatgga
    16561 ttcttcccaa aatgcagcaa tcgaacaagc gttaaaactt gcagacaagc cttataaaat
    16621 ggaattcaaa ggcgtatatg tcatgagtgt agagaaaaca tcgaatttct ttggcaagct
    16681 ttcagttgga gatacagtaa caaaagtaga cgggaaaagc tttcaaagta cagaagcatt
    16741 tatggattat gtaaaaagcc aaaaagttgg acaaacaatc gaaatcagtt atttgcataa
    16801 tggtgaagaa aaaacagctt ctggtgatct gatcgagtta ccaacagata aaaaggcagg
    16861 aataggtatc acgcttactg accataccga gatcgaatca gatacagatg ttcgtattaa
    16921 ttctggctct atcggtgggc catcagcggg attgatgttc actttagaaa tctatgaaca
    16981 agtcactggt aaaaacttgc gacatggtaa gcaaattgca ggaactggaa cgatcaacag
    17041 tgaaggagaa gttggccgaa tcggaggaat cgataaaaaa gtggcaagtg cggataaagc
    17101 tggcgtagag attttctttg caccagatga tacgatttca gacgatgtta agaaagaata
    17161 tcctgaaata aaaaccaact acgaagaagc aaaagctgcc gctaaaaaat tgaattcctc
    17221 aatgaaaatc gtaccagtaa aaacagtaca agaagcgctt gactatctag agaaaatgaa
    17281 atgaaactaa ataattaaat aggggttgtg acacgagttc tgtcacaacc cctctttttc
    17341 gtcaaaaatc ttcacgataa aaataaaaac aaaagaaaaa attgacgtaa ttagatgttg
    17401 aagggacgat tttgccagag ctcactgttt cttcaatttt aaatgaaagg agtaatgaat
    17461 gatttttact ggtcattctt tgaaaaaaga acaatgatag aaaaaatcag caagaaaata
    17521 ctagcttcac ccaaattgat catttggatg tctatgatag ttcttatctt ttgtatcgca
    17581 agtggttttt tattatcaaa tttgctattt tatagagaaa cagaagagac tgctgcaaaa
    17641 gaaatacttt cttcgtttag ttccagtgga gaagatccat cagctgaagg aaacgatgta
    17701 gaagaggatg ctcgtccaaa ggtcatgtac accgatatca aaggaagtgt gaaggagcct
    17761 ggtatctatt ccttttcttc agaagaacgg gtctatgatg tactaaagcg tgcaggtgga
    17821 ttattagaag aagcggatag cgatcgaatc aacttttctg cgaagataga agatcagcaa
    17881 gtcctatata tccctgctgt aggtgaagag ctgccagaac atcttgatca gttggcatcc
    17941 tcggaaggaa aacagcctac agcagattcc gagcctccca aaataaatat caatacagcc
    18001 actccatcag aacttcagca gattcctggg atcggatcag tcaaagcgca agaaatcatt
    18061 cgatttagag aagaaaacgg atccttccag aaagtggaag acctgcagga gatttctggt
    18121 atcggtgaaa agacagttga aaaactaaaa aacttcgtta caattaaata gaatgattca
    18181 aaatcgactg gcacgagcaa taaatggacg ctaatggata ctaagaataa tccaattcta
    18241 agagcttggc aggacgagga ggtagtattt ttggatagga aatagcttga ttgttcgcaa
    18301 agaaacatta aaaaaaccaa tgctgaatgt ctatctccaa aataaaatat ctgggattca
    18361 tattatgaat acggctgtca gcggcaataa cagtcaagct ctacgagaac gctttgccaa
    18421 agatgtactt agctatacag cagataaagt atttattctc attgggacga atgatctagc
    18481 agagcataaa caactttcta aagaaacgta ccaaaaaatc tgcagtggat gatagttcag
    18541 ctgaaaaaag actatagttc tgatcatgct ttctttatca cgccaccagc agtcgatgag
    18601 acaaaacaaa aatatcggaa taacaagttg atcaaagaat atatctctgt tctcacagaa
    18661 gtagcaaaac gccatgattg tgaagtatcg atttttatac ggaatttctt gaacaaatgg
    18721 attcgaagaa tttttataat gggctaatgg atgacggact tcatttcggc agtgaagggt
    18781 aggatctttt gtcagacagg atgattcgtt atatttaaag aatattttgt ttaagcaatg
    18841 agtacttttt aatcaacttg aaaaaacgga ggaatataaa acatgttaga aaaatcttca
    18901 aaagcatgcg atacgaataa agaaaaagtt actgataagt cacataatga acgcattcct
    18961 tgggaccagt actttatggc tcaggcagta ctgttatctt tacgtagtac gtgtacacgt
    19021 ttagaagtag gagcgacact cgttcgagaa aaaaggatca ttgctggcgg ctataatgga
    19081 gcagtcagtg gagatgtcca ctgcatagat gaagggtgtt acgtcgtgga tggacactgc
    19141 ttgcgaacga tccatgcaga gatgaatgca ctcctacagt gtgcaaaact tggtatcccg
    19201 acggaaggtt cagaaatcta tgtcacacat tttccatgtt tggcctgtac aaaggctttg
    19261 ttgcaagctg gtgtgaaagg gatcaattat ctccatgact atcgaaatga tccttatgcc
    19321 caagcgttga tcgaacaatt aggtgtatct gtacaccaag ttgctttaga ctcacagcat
    19381 ttttcaaaac ttcaaaatga attaacagga aaacatgtct agcgttttag aaaggcatgt
    19441 tcgaaatcgg ttgatttttc cggcaattac gtcgatgatt atctgtttgt tgtattacac
    19501 tgacaattgg ggttatcgtt tgcttcttgc cggaattttt ttatggtttt cgctaaaaga
    19561 aggacgtttt atcgcgtact tgtgtatttt gtgtagcata acggtatcca tttcttatag
    19621 gctacaagag tattcatttt tagaggaaaa aacaacatct gcgcaaatta ctgtatttac
    19681 agatacgatt cgtgcaaatg gtaatttttt gacaatggaa ggaaggttat cagagaataa
    19741 acaaaagctc cagctttctt atcaagtaaa cacagaagca gaattgaaaa catggcttaa
    19801 cttccgagga aagggaatag aattgactgc tgaaggcgag ttcatctctc cagcaaaaaa
    19861 gcggaatctt tataattttg accaagaagc ttacttcagg aaccatagaa tttctggacg
    19921 gttccaaatt caaaagattg aacagatcac catgcaaaat cactggcgaa actggcttca
    19981 gagaaaaaga ggatctttta tctcctttgt ccaatctgaa tttccgcaaa aaacaagtgt
    20041 atatattaat tctttattat ggggctataa agatgcagga ttcagagaac cagaagaaat
    20101 ttttagggag agtggtttgc tgcatctgtt cagtctatcg ggtctacaca tccaatttta
    20161 tttagggtgg ctgtattatt tgtttcgacg tatcggatgg ccactacacg tcagtattat
    20221 tccgttgagt ctactaacta tctgttatgt ttctattgca ggaagttcta tttctgtttt
    20281 gcgtgctagt ttgctgtttt tattgcgatt gctagtcaaa ttgctgaata agcattattc
    20341 caccatggac ttatttgcag ttgtcttttg gcttctttta ctatttgatc ctcgatttct
    20401 ttttcatgcg ggtggacagc ttagtttttt catgagtttt ttgtttatcc tgatttcttt
    20461 tgatggagat tggttgaaaa aaacggcctc tcacgtcctg tttactatga tcacgatgcc
    20521 gttgattgta tggcattttt atgagtggcc tattttaggt agtcttttta cattactgat
    20581 tgcaccggta ttcaagtttc tttttcttcc tggtgtgtta tttctcacac tcttcaatcg
    20641 ctggctgccg gaaactttac ttttgctgat agaagaggga ttaatcttat ttgagcgaat
    20701 aatcgatttt tcttcagggt cgtctctcat tataggacgt ttgccccttg tgctatctgg
    20761 gatgtatatt ttcggattac tgatttgtat ggataggttg aaagaacaac ctgtgaaaca
    20821 cttgttttat gttggtcttt tttcttttat ttttttgact ttgccatttt tacgcttttc
    20881 ttcaacgatc gcttttatcg atgtcggtca aggagacagt atctttttgc aaagtccttt
    20941 tcgaaaagaa acgattttga tcgatactgg aggtcagtta cactttgaaa gagaaaagtg
    21001 ggcgcaaggt atgatacgtc ctcctgctga aagaaatatc gttccatatc taaaaggtca
    21061 ggggataagt gtaatcgata aactcatctt gacacacgac gatacggatc atgtgggaga
    21121 attacccacg ttatctcagc attttactat caaaaaaatt tatatcggtt ggggcgctgg
    21181 acgaaatgag ccattacaaa ggcatttatc tgaagctcaa aaaaatggta ctgagatcat
    21241 tgaaatcaaa catggggaca ggatcagcgg ttattatgat ctttatgtat tgactccttt
    21301 tgaaaaggga gagggaagaa atgaagattc gattggtcta tggatggaat ataacaatag
    21361 gcgcttttta tttttaggag atttgaatca agcaatggaa aaacaattgc ttttgattta
    21421 tcctaatctg aaagccgatg tagtcaaatt aggtcatcac ggtagccgta cgtcaagtaa
    21481 cacagatttt ctttcccata ttgaagcaaa acatgggatt atatcctgcg gcgtaaataa
    21541 tcgttatggt cacccgcaca gcgaagtatt ggagacacta gaagaaaatc agataaaaac
    21601 atggcgaacg gatcaacaag gaatgatcac ctatcgctgg catccagttt ttcatcctca
    21661 tgggctagtg gaaacaatga tagactagta attctcatct gctcatggta ggataatttt
    21721 tgaaagtggt gagtaatttg agtatacaag cagagttaca aaaaatacgt aaagaaaaac
    21781 ttgcatcttg ttacttgatt ttaggaacag aaaagtttct ccaagatcaa gttcggacag
    21841 aaattgtcaa aaaaatccaa ttagagggcg aagatgactt aaatttttta agttttgaca
    21901 tggaaaatgc aagtttagat gaggtagtag ctgaagcaga gacgttgccg tttttcggag
    21961 atcaacggtt agtattcgta gagaatcctt attttttaac aggtgaaaaa gtaaacaatg
    22021 gaatcgaaca aaatactgat ttattgacgg cttatttgaa agaaccatta gaatcgactg
    22081 tattagtatt ctttgcgcca tatgaaaagt tggatgaacg gaaaaaagta acgaaacaat
    22141 tgaaaaaaac agcaattatc atcaatgtcc aacagttgaa tgaaaaagaa gtacgtcaat
    22201 atctgatgaa taccttagag aattcctcaa tcaaaatgga acgaagtgca attgatttat
    22261 tcttgaggtt gaccgactta gatttatcca aaatgatgag agagttacag aaattggtcc
    22321 tttatggaca aaatcaacag caaatcacgg taagagaagt agaagaatta gttcctaaaa
    22381 cgttagaaca taatattttt gacatgaccc aatatatttt aaaagggaag acggaacaag
    22441 ctttgcgttt atacgaagat ttagttatgc aaggggaaga aacaatcaaa attaatgcga
    22501 ttttgctttc tcaattacgt ttatttttac agacaaaatt tcttgtaaag attggttatc
    22561 agcaggcaaa tattgctgaa acattgaaaa tccatccata tcgtgtaaaa cttgccatgc
    22621 aggaagtaaa aaaattcgat gaacatttgc tggtacagtt gtttgatcaa ttagttgaga
    22681 tggattatca aatcaaaacg ggacaaatcg aaaaagaatt aagttttcaa ctattcgttt
    22741 tgcgcacagg gcagttgtta agaaatcgat aagaagaaag acgagggcaa agcatgcggg
    22801 aaggtcgttt gtttttgtcc tttttttgac aaataaaaaa atcggccgaa gccgattctt
    22861 ttatttagcg atttttttgc ttaaacgaga tttgtcgcgg ttagctttgt ttttgtggat
    22921 tagacctttt gattcagcca tatcaatagc tttaacagct tctttatata acgcatctac
    22981 gttgtcagca cctgaagcta cagcatcttc aaattttttg attgcagtac gcatagcgct
    23041 tgtttgagat gaatttttca cattagcgtt ttcgcttgta cgaacacgtt tgattgcaga
    23101 ttcaatgttt ggcattagtt tcacctccga taacttaagt tcttacgcgt gttaccgcat
    23161 aattcaacat tcattattat acctaaaggc agcgtgcttt gcaatatgaa catgacaagt
    23221 ttttttcctt aacagtcttt tattaggatt ttttttcagt aaaaacggat agtacaagct
    23281 gaaaaaaatc aaaaagacgc tattgtggga ggcaatagcg tcaaaccaaa ctagattttt
    23341 atttatctat ttaaacaaag tttgaatggg aatgtttggt actaagttat tatataacaa
    23401 agagaaccgt ttgcaaagtt ttttttgaaa agggatacga ttccctgttg ttctttgttt
    23461 ttctattaag aaactgcagt tattttataa ccagtatcct ttgatcagta aaggctattc
    23521 tggtgtaccg attattttaa tgtattcatc gatatttttt atcaacattt tttttatgac
    23581 caactggttc cgacggttcc atttgccact tacttccagc acatatttat ttaggggcaa
    23641 acgtaagata tattttgcca aatagcgatc tttaagcagg ccattgatca cacggtcctc
    23701 aagctgcaag ttgatcccag tcagcatcat tggctgttct tgtaaaacgt acgtatcaat
    23761 taaaagacct tcaaaagttt ccacaagcgt cttcctttct tttcaaagta acctgaaaac
    23821 aggcactaat tcttccattt tgatattcgt tgaagtggat gcgatcattc tttcttttgt
    23881 ccactgtaat ctagtataac aaaaaagagc agaagagcca aaaagaaaaa agagcatcga
    23941 attctatagg aagtctcatt ggcacggcct aaattattac aaaacattga ttaaaaaaag
    24001 cccctgcatc gcaggagcat cccctatatc gttttaatag gtcaatcaaa aagcagtatc
    24061 aaacacattt tgtatcaaat caggaaataa tagataagct aagcccagaa tcaaaagtac
    24121 cgctagaaga aaccagccga ttgttcctat gaaatacttt aatttttcga acattgtatc
    24181 acctcgttgt cagtatatca cggatcagta aattgggggt gttaagaatc tcctaaaata
    24241 gacaaaattt gttctatttt cctaaagcaa atacttgtaa gatacagtaa gtgataccag
    24301 aagcaatgac cggtccggcg gcgattcctc ttaagaagac aacacctaaa atcgtgccga
    24361 aaacaagtgc aacagtgatt tgtggatcag aagcaatcaa tcctacaccc ttggaagata
    24421 agacagccac tagcccaccg caaaaaacag ctacccagcc aataggggat ttaaaggctt
    24481 ctaatagatc acgtagaccg atttctcctg ttgcgatagg gattagaata gccgctgtga
    24541 tgatcgtcac cccaatattg attcctttgc cttgaagcca agggaaaaag gaacgggagg
    24601 ctggtatgag cttcataatc aaaacaaaag ctgccgctat catcagactt tgatttttag
    24661 ctaaaattgc tacaagtaaa ataattccta aaaaaagcca actttccatg aaatatattc
    24721 ctcactttct tcgaaacaat cataacatgt ttttagaaag ttacaaaagt aggaattcat
    24781 ccttcaagac ctattcataa gctgtttttt tcataaaata aacaaaatca taaaaaaaca
    24841 ctttgcttat ttgacagaag acagccgcgc tttgtatagt ggacaagact tacatttttt
    24901 tgaagaatca gaaagatcag gtaaaggtct tagtaaacgc aagccattca gaataaccaa
    24961 tattgtgctt ccttcgtgtc ctacaactcc aagaggtaga tttaaaaatt gcaggaagtt
    25021 agaagcaatc aacaagagaa taacaagaat cgaaaaaata atattttgtt tgatgatccg
    25081 ccgcattttt aaagatagcc gatgactgta gacaaattta tttaagtcgc ttttcattaa
    25141 gacgatgtct gcgatatcca tagcggcatc tgtcccttgc cccatagcga cacctaaaga
    25201 agcggctgct aaagcaggcg catcattgac tccatcacca accatcgcat ttacttggta
    25261 aagttcattc tcttttttga ctagttgtgt tttttcttcc ggagtacagc ttgcatagta
    25321 atgttcaatc cctacttgtt cagcaatggc ctttgctgtg ccagaatggt cgccggttat
    25381 catacttgta tggatgtttt gggatttaaa gtaggaaatt acttgttggg tatttgcttt
    25441 tggaatatct agcagaccta aaacagcaat taactgctga tctttagaaa gataaatcac
    25501 ggttttgcct tgattttcca aacgttcgat catttccgca atctctttgc tgattatcat
    25561 cgtctcagga tcatatgcgt gcttgccaac tttccattgc gcacctaaat aggtagtttg
    25621 taatccaaaa ccagtaattt cttctattgg taagtattgg atttcttcag gtattgtgca
    25681 atcgaaatat tgcaaaatcg catgagcaag tggatgcgtc gttttttgtt ccatagcaac
    25741 aagaagttgt tgtgccaaat ccttttcatc aaagaaaaag ctgtcagtta caactggttt
    25801 tcctttagtg agcgttcctg ttttatcaaa ggcaatcgct tttaattcag aaagcttttc
    25861 taaatggata ccgcctttga ttaaaatccc attttttgca gaatttgaaa gagcagctag
    25921 agaagctggt gtagcagatg cgacaagcgc acaaggagaa gccacaacta ataataccat
    25981 tcctcgataa aagctttcat cccaactcca acctaggaaa aagtggggga gaaggatcat
    26041 tagaggaaca gcaagcaaaa tcaattttac ataattattt tcgattcgtt cgataaatga
    26101 agctgtttga gttggcgtat tctgcgcttc ttctactaat tggataatct tagcaaagac
    26161 agtttcggaa ctcgtttttg ttactcgaat cgtgatggga tttccttgat tcagcgttcc
    26221 tgcatacatc tcatcgccta aatatttttc tacaggcaca gattcaccgc ttaatgcaga
    26281 ctcatcgatc gttgcctgtg tgctttctaa aaagccatct atcggaacag ctgctccttt
    26341 agcgacaaat accaagttat ccacctttag ttgagaaaca tctacttctt gcatttgtcc
    26401 attttctttt aataattggg ctttttgtgg ttgaagattc atcaaagcag taatttcttt
    26461 ttgactttta ttagttgtgt attcctctaa tgcaccgctt aaacaaaaga tgaatgtcaa
    26521 cattgctcct tcaaagtaat taccgatcaa acaggcacca atagcagcta aagccatcaa
    26581 taaatccaca ttcagtgtcc gatcattcca caattctttc aagccttccg atgtttgttt
    26641 atatccaccg atgataatgg cactgatata aaaaagtggg gtgatggtaa gagagaatcg
    26701 gtcgaagata aaaccgaaga tcataaataa aaggcagccg attgttgctg caaaagcttt
    26761 tttctgatta gtcatcgtta ttagacctcc ttgtcaaaac aaggatagca taataaaaat
    26821 gtaattgata ataataacag ctaaatgaga acgataatgg ttatcatttg gtgattaagc
    26881 ttgatgttgt ttttattatt tataatgatt attattaaag aaaataaaaa accagaacat
    26941 ttctcaaata agagaagtgt tctggttttt tctacattgc aataaaccaa taaccaatca
    27001 aaatgatacc aaggataata cgataccagc caaaagcggt aaagtcgttt ttcttcaaat
    27061 agcttagtaa gaatttgata gctaagacgg aaaccacaaa agatacgaat gttcctacaa
    27121 gaagaacaac agtttcttcc attttgaatg aattcccttc agctaaatat ttgacgatct
    27181 tcaagccgct tgcgccaaac atgacaggaa tccctaagaa aaatgaaaac tctgtagcga
    27241 caaaacgcga agcaccaatc aagatagatc ctaggatcgt tgcgccagaa cgggatgttc
    27301 cgggaacaag tgccaagact tggaataacc caacaagaag agctgcttgg tacgtaaagt
    27361 cattcagaga agtccaacga ggtgttttgt ttttgttgcg tttttcgaca ataataaagg
    27421 caataccgta aacgatcaaa acaatggcaa ctggtaagaa cttgtggaaa tttgcttcta
    27481 accaatcatc caaaggcaaa ccaatgatga tggctggtat gcaagcaacg atcactttaa
    27541 accaaagtgt ccacgtatct tttttttcta ccgttgattt acttggagaa aatgggttta
    27601 acttgtgaaa ataaagaacg acgacagcca agatcgcccc taattggata acgacattga
    27661 acatcgacat aaattgtgaa ctggcatcca gtttgatgaa ttcatctgct aggatcaaat
    27721 gaccagtact actgatgggc agccattccg ttattccttc aataataccg agaatcactg
    27781 ctttgataat atttgcaaaa aacataaatt ccttccttcc caattaagat acatcttata
    27841 gtataccgtt attttttgag aaacccaatc tgttttttaa tattaagaaa aacttgagaa
    27901 ataaagcaga taagtacacg aagagaaaaa agaagacaaa gccctcgttc agactttgcc
    27961 ttttatgatt ctctggtaaa aattaaaata tccccattat agaaacgagt cgcgactatg
    28021 tgttttcccg ttatcgatat aagacgtatc attgatgccg tggatagaaa atcgaccgtt
    28081 tgcataagtg acctttgtta cgctgccatt taaaagccca gcacgaacag gctgtttagg
    28141 atcgatcaga ttaagcaaaa aggcgatcgt caaaccatga gatacgacta aaacatttcc
    28201 accaccattt ttttcgcagt gatgggcgat atcttcaaat cctgtccata cacggtctcg
    28261 caatgtttca taagtttccg cccacccagc ggtatctaag ttgtatacag cattagcaat
    28321 ttgttcaaaa gaaacttctg tggtaaacat ttcatcatat gttttaaaat tcaatacacg
    28381 agggatcaca ccccacattt ccatgtcata tccaccttca agagacccga aacaccattc
    28441 tctaatcctt ttttcaataa aataaggaat ttcttttccc ttagaatgtt ctcctagaat
    28501 aatacgggca gtttcgattg cacgaccact gtcactagaa taagcaaatg aaaagtcgac
    28561 attttttaac ccgcgaccta aataatgaat gccttcttgt ccttgctttg tgaggggtgt
    28621 atcacaccag ccttgtactc gttcaattgt attgaacatc gtttttccgt gtcgtacgat
    28681 ataaagtgta gtttctgtca ttttattctc ctcctaagtc gttttaacga ttgaaaaaag
    28741 gatttgtcct tttttcctgt tcaatcgtcg ttgcatcgcc atgtcctgga tagactgcaa
    28801 attcatcagg taatacaaac agctgggtcc gaatactatg aagtaattgt tctaaattcc
    28861 ctgtatacag atcggttcta ccgatacttc ctctaaacag ggcgtcgcca gaaacgacaa
    28921 aatcatcaaa aataaagctg acgcttccta tagaatgccc tggggtaggg acgacgcgaa
    28981 aagacatgtt tcctaaagta taagttttca tttcaaattc atattctgca ggcgagacaa
    29041 taacatcagc aatatcatca tgtctaccga gtccagaaag attcaaaatc ggatcaccta
    29101 gccatttttg ctctagtggg ctgacataaa ctgggatttg ataatacgcg cgtaaaggtt
    29161 ccactgcacc gatatgatcg tagtgagtat gggtaagcaa aatcgctacc ggctgttggt
    29221 ttgttttttt gatttcttgt ttgattcgtt ccgcatcttc tccagggtca atgatcaaaa
    29281 gtgcttcttc gttgtagacc aaataacagt tttcttcaat cattcctgtt tttaatcttt
    29341 cgatatgcat gtgcattcct ccttgatagc caaaacttct ttcatccatt agtataacgc
    29401 attcattgct aggaaacaaa aacaggtact tatttctctt tacttatctg aattatcaga
    29461 ctatatgaaa agtatttgga tattctaaag agaaggaaag taagttttca tagcatttta
    29521 atatgtcctt gttacattag attcatccaa aaatccaaat tctatatcct atatccctgc
    29581 ctaatcagca gggtgttttt ttatgtttgg aaagagagct ctttttgcta aactaggttt
    29641 tttcaggtaa tcttagagag aaagaggtgg tggaaatgat caaacagtca aaaatatctg
    29701 tgcggcactt agtagaattt attttgcgac gtggaagtat cgacaatcgt aaaaaaagta
    29761 accatactgc attagaagga gcgagaatcc accgcaagct ccaaaaagat gcgggagaaa
    29821 actatgaaaa agaagtcttt ttaaaaacaa cagttcaatt agatgaatat tacctgatcg
    29881 ttgaaggccg tgcagacggt attttcaaaa gagacggtat ttattatata gatgaaatca
    29941 aaacctccga accacgattt gaagatttag aaccagaaca agtggaactt ttctttcatc
    30001 aagcaagggt gtatgcctat atctatagtc aagaacatga tttacaagaa ataaatctgc
    30061 aattgactta cttccagacg gcagaagaag tgatcacgag aaaggttgaa catcagacaa
    30121 gagagcagtt agaaactttt tttaaaaagc tgactgaaga ttataaagaa tggcttgttt
    30181 ttcaagaaaa ctggcgcact gtacgcaatg cctctttgat ggctttgaaa ttcccccatg
    30241 atgagtatag gaaaggtcag cgtgaactag cggtagctgc ttataaaacg atccgtacga
    30301 aacagaaatt gtttgtagaa gcacctaccg gaacaggaaa aacaatctct acgttattcc
    30361 ccgctttgaa agctgtaggg gaagaagagg gagaaaagat cttttatcta acggctaaaa
    30421 caataactag acaagtagct gaagatgcta tgacagcatt aaaagataca ggagctgaag
    30481 taaaaagtgt cactttgacg gcgaaagaca agatctgctt tttagatgag acgacctgta
    30541 atccagatca gtgcccatat gccaatggtt attacaatcg gattaatgaa ggtttatggg
    30601 atcttttgaa tcatgagaat cagatcactc gtgaagtcat cgaaacttat gcaagaaagc
    30661 atacactttg tcctttcgaa ctatcattag atgtcagtat ctggtgtgac gtaatcattg
    30721 gggattacaa ttatttattt gatccaactg tttatttaag acgttttttt gaagatgaaa
    30781 aaaacgagga ctatctgttt ttgattgacg aagcacataa tttggtgaat cgttcccgag
    30841 agatgtattc ggcagaacta tcttatgaaa aaacgaaacg aagtaaggaa gctataccaa
    30901 aggaattcaa aaaacttcat cgccgtttca acaaactatt aaaagaattt gattcgatcc
    30961 gagaaatagc aaaagaagat cattgggatt atcatcatca aaaagcaccg gctgaatctt
    31021 tagtaaaggc aggttatcaa ttaagcgaaa aaattaaaga atggctggca gaatttcctg
    31081 agcacccatc acaagaacaa ttgcttcctt attattttga tttgcttcat tttttgaagg
    31141 tcagtgaatt ttatgatgat cactacgaaa caacagtcga aaaaacgtat cgcgatctga
    31201 tagtaaaaga gttttgtatt gatccaagct tgtttcttga gcagtcgttg gataaaggaa
    31261 aaagcagtat tcttttttct gctagttttt caccactctc ttattatcag gaaacactgg
    31321 ggggacaaaa aagtctggct tacaaactgc cgagtccttt cccagaagga aaccagcaag
    31381 ttttcatcgc aaattaccta gagacgactt atcgaaaaag ggaacacagt ctggcaaaat
    31441 tagtagagac gattcatgct tttgctgatg gaaaggtcgg gaattatttc gttttctttc
    31501 cttcttatca atatttagat cttgcggtgg aagcattcag acagcaatat cccgacagca
    31561 atgtgctaat ccaagaaacg gacatgaatg aggaagaacg cgaacgattt ttaacaaaat
    31621 ttcaaacaaa tcccgctgaa acattgattg gattttgcgt acttggcggg attttttcag
    31681 aaggaatcga tttgagaggg gaccgattga tcggcagtat gatcgtaggt gtaggtttgc
    31741 cgcagatgaa tcatgagcag gaactgatca aatcatatta tgatgagaag gaacaccttg
    31801 gatttgctta cgcttatcag cttcctggaa tgaacaaagt cttgcaagct ggtggtcgag
    31861 tgattcgtgg catggcggat caaggaatcg ttgtattggc agatcaacga ttttctagtt
    31921 tttcttatcg acgtttattc ccacaacatt ggcaaacagc aagagaagta cgaagtgttg
    31981 gggaattgga agaaggaata cagcgttttt ggttatcaaa agaagcagta aatcaaaaaa
    32041 acgaggaatg acagacgtca gcctcgtttt ttgattaacg atagttagtg aattgcaact
    32101 cgattggtaa gtcaagttta cgtaataaag caatcacagc ttgtagatca tcacggttct
    32161 tacctgtcac tctaatctga tcttcttgga tttgtgcttt tactttcagt ttttcatttt
    32221 tgatagctgt agtgattttc ttcgcgtttt cacgatcgat tccgttgacc aaatcggcag
    32281 tttgtcgagc tttgccacct agagcgtgtt ctgattcgga aaaatggata tttttgattg
    32341 gcacatttct tttgatcagc ttaccaaata atacatcttt gatctgttcg attttgaaat
    32401 catcatcgct caatacaact agattgctgt tctctaattt gatttctact gtagaatcct
    32461 tgaagtcaaa gcgattggac aattcttttg ttgtttgctg aatcgcattt tttacttctt
    32521 ctgtattgac ttctgataca atgtcgaagc tagcatcttt tgccatagga accctcctga
    32581 tatacatata aatatttacc atacatctat cttatcatag gattagggca gattcttacc
    32641 tgtttgctaa aattcttctc atttgagttc gaagtatttt attttaatag ataaactgtt
    32701 attcttacat ttggaatacc aaagtagggg agaggtgctt gtgagtaaaa ttatgactgc
    32761 gtatcataaa aatgaaagat taaagaaaat agtggttatt ttgataaccg gattgaccgc
    32821 tgcggtcgct ttaaattatt ttttgattcc agccaatgtc ttttctgcag ggatgaatgg
    32881 gatcgctcaa atcatttcct cgcttttata tgaatggttt catatcaaga tagacacagg
    32941 aacatttatt tttcttttga atatccctgt gtttgtatta gggtttctca aagtaggaaa
    33001 acgagcaacg atccttagtt ttgtgaatgt tgtatgtgta tcggtgatga cgatgctgct
    33061 tccagtcgga cagatcactg ataatatttt gatgaatgcc ctagtaggcg gtgttttatt
    33121 aggtcttggc gtaggattat ctttaaaaat gggctttaca actggtggga tggatatcat
    33181 ctctcttgta ctttcacaaa caactggaaa aacagtcgga aactacatgc tgattctaaa
    33241 tggtatcatt gtagtcatcg caggcttctt ctttaactgg gaaagtgcct tgtatacgat
    33301 tatttccatt tatgcaatga ctcaagtaat tgatgccatc cacacgagtc atcaaaaagt
    33361 aacagcaatg atcgttaccg tcaagccaga agaggtaaca gaagaactag caaaacggat
    33421 ggtacgtgga atgacattac tgccgtctgt cggtggctat tcaaaaaaac aagggaacat
    33481 gatcatgatg gtcatcaccc gctacgaaat gtatgatctt gatcagatcg ttcatgaaat
    33541 cgacgacgat gcatttatca atattttacc aactcattca gtatttggcc ggtttgcaaa
    33601 tgaaaacgaa caaaaaatgt atcgaacaac tggcgtattg ccagaaataa aaaatcgttc
    33661 acaaaaaaaa tgaggaatca ggtttatttt agaataaatt taatctatta catctaataa
    33721 gaacattttt ataaatttaa acgagaatct tacttctaaa ttctcattta caagcagcta
    33781 aaaaaagagt atgataaata aaaatcgtgt taaggagtgt cgtacgatga gcgaagcaaa
    33841 ccaagaacgg tctggacaag aaatagaact aatcaaagaa cgtattcttg ctgccttgga
    33901 aatggtgatt gatcctgaat taggaatcga catcgtcaat ttaggcttga tttatgatat
    33961 agaattcaat cctgaaaatg gagaaacagt cattaagatg actctaacaa ctatgggctg
    34021 tccattagca gatattttaa cagaatctat ccatgacgca ttaaaagaag tgccagaagt
    34081 aacgaaagca gaagtcaaac tagtctggta tccagcatgg acgacagata agatgagccg
    34141 ttatgcacgg attgcgttgg ggatacgata gaaatcttgg ctgactagct atgagaagca
    34201 aataggaaaa acaaaaaagc cttttatcct ttctagaaga aaagagataa aaggtttctt
    34261 tgtttataaa attttgtctg ctatattata agttaattaa ataaatgtgt tctattgata
    34321 aaggacattc aaatcccttt ccttttggaa tccttctttt ttacatcagt ttgattttcg
    34381 tatagtattc tttctcatct tcacgataaa tcgcagcccc atttttttgt tgtgctttaa
    34441 gactgccaag atttttttta tttacagaca aaagtgcctc atcaatgccg attttttttg
    34501 cctcttgtag tactaatgct aatccttgtg tggcatatcc ttttttacga taattagggg
    34561 agatgccgta accaatatgg ccagcgccgt ttcttaatgt ttcgttcagt ttatggcgca
    34621 aattaaaaat tcctacatac tcatgttcat cactttctaa aataaagacg gttgcgggaa
    34681 cgtaactctc aggaagatcg attcctaaag acgttttttc gcattttttt acataatcta
    34741 aaaattcagc aaatgtatag ccataagcat tgttgataaa tccactctca tttggtccaa
    34801 agctagtttg tagctgataa gctttcttta aatctgcttc ccatagtttg atcagtttca
    34861 tcgtattcac ctctttaagt aaccttattc atttgttttc tactatagca ctattgttgt
    34921 aaatagccat gcctattttt atttattgtg tcatatcgta ttaagaatca tcgaacaata
    34981 caaatatgaa ttacaataaa aaaattattt gaagttcgtt cattcgttac ttatgatctc
    35041 tagaagaaag aaaacgtgaa ttacttcagc gtctagaatt ccagaaggat agtaatcaac
    35101 agaagaaata atcaatatcc aaatgaaaga agatagctga atcgagaaaa agaggaaaaa
    35161 agaaatgaag aaaaaaataa aatagttact aatcccagag tcgttcgttt aacattgaaa
    35221 tcgatcatat ggataaaaca gattttttca ccaaccctca atagatgatg gagttgctcg
    35281 gatgaattat ttgtgtagat ggcataaggg agggcgtaca gaaatgaaaa agaacaaaaa
    35341 tatgttcttg acaaaaaaca catgtaatcc taaactaaaa gatgtgatgc ggctatggcg
    35401 gaattggcag acgcgctagc ttcaggcgct agtgagggtg acctcgtgga agttcgagtc
    35461 ttcttagccg cataatttgt ttttttataa agagaaggta cacctggagc gatgagaaag
    35521 aaaataacat attatctaaa agaatatagg aaaaatttta aacaacggaa ccagattcaa
    35581 ataaatcaaa aaaaatttgt gtgaaggtgg gacagtttaa aacctaatag attgattcaa
    35641 atagtagatt tatagattct gatacaagaa atactggcaa acgatagtta aggaataaag
    35701 actaaactta aactcaaaaa gaggtcatgc gaaagaataa atcgcatgac ctcttactat
    35761 attttgaatg tgtttaaacg ttcaaataat gaatcttagt accaaccgtt tgcttcccag
    35821 aatgctttcg ccgcttccca agaaccataa cgtgaagtaa catattgttc tgctactctt
    35881 tcttggtttg cagcagagta gtcaccattt aagtaagaag aatctaattg gtaacggccg
    35941 atgtaacgtc cgttcgttgc tgtgtaagaa ccgcttgatt ctttttgtgc gatccattct
    36001 tttgcagagc ttgtacttgc tggagtagca gcagtttctg ttacagcagg agcaggttgt
    36061 gtttcagcaa caggcgctgc ttgtgtttcc gtttgaaccg tttcttgtac aacaggttgt
    36121 tcagcttgaa caggttcagc ttggactggt gcttcttgaa cggctgcttg aggttcagca
    36181 gctgcttgtg cagagccttc tgttgggatt gttaattgtt gtcctgagta
//
LOCUS       DADLIO010000022        34962 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.022, whole genome shotgun sequence.
ACCESSION   DADLIO010000022 DADLIO010000000
VERSION     DADLIO010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34962
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.022"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            156..1862
                     /locus_tag="JOX41_001245"
     CDS             156..1862
                     /locus_tag="JOX41_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin/fibrinogen-binding protein"
                     /protein_id="HAY6449001.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2020..2922)
                     /locus_tag="JOX41_001246"
     CDS             complement(2020..2922)
                     /locus_tag="JOX41_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAY6449002.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2919..3623)
                     /locus_tag="JOX41_001247"
     CDS             complement(2919..3623)
                     /locus_tag="JOX41_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HAY6449003.1"
                     /translation="MKKNMDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKG
                     EETKIEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSE
                     HIINGKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVN
                     PDVFFPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPI
                     QPLNGREIYYFEEFEQ"
     gene            complement(3654..4295)
                     /locus_tag="JOX41_001248"
     CDS             complement(3654..4295)
                     /locus_tag="JOX41_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAY6449004.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(4333..4647)
                     /locus_tag="JOX41_001249"
     CDS             complement(4333..4647)
                     /locus_tag="JOX41_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449005.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            complement(4635..5264)
                     /locus_tag="JOX41_001250"
     CDS             complement(4635..5264)
                     /locus_tag="JOX41_001250"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HAY6449006.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            complement(5271..5987)
                     /gene="pyrF"
                     /locus_tag="JOX41_001251"
     CDS             complement(5271..5987)
                     /gene="pyrF"
                     /locus_tag="JOX41_001251"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HAY6449007.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            complement(5984..6916)
                     /locus_tag="JOX41_001252"
     CDS             complement(5984..6916)
                     /locus_tag="JOX41_001252"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HAY6449008.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(6913..7689)
                     /locus_tag="JOX41_001253"
     CDS             complement(6913..7689)
                     /locus_tag="JOX41_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HAY6449009.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(7743..10928)
                     /gene="carB"
                     /locus_tag="JOX41_001254"
     CDS             complement(7743..10928)
                     /gene="carB"
                     /locus_tag="JOX41_001254"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HAY6449010.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(10933..12009)
                     /gene="carA"
                     /locus_tag="JOX41_001255"
     CDS             complement(10933..12009)
                     /gene="carA"
                     /locus_tag="JOX41_001255"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010744830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HAY6449011.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(12014..13294)
                     /locus_tag="JOX41_001256"
     CDS             complement(12014..13294)
                     /locus_tag="JOX41_001256"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HAY6449012.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(13313..14239)
                     /locus_tag="JOX41_001257"
     CDS             complement(13313..14239)
                     /locus_tag="JOX41_001257"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HAY6449013.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(14252..15535)
                     /locus_tag="JOX41_001258"
     CDS             complement(14252..15535)
                     /locus_tag="JOX41_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HAY6449014.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="JOX41_001259"
     CDS             complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="JOX41_001259"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015694870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HAY6449015.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(16323..17234)
                     /locus_tag="JOX41_001260"
     CDS             complement(16323..17234)
                     /locus_tag="JOX41_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAY6449016.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(17231..17695)
                     /locus_tag="JOX41_001261"
     CDS             complement(17231..17695)
                     /locus_tag="JOX41_001261"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HAY6449017.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(17700..18398)
                     /locus_tag="JOX41_001262"
     CDS             complement(17700..18398)
                     /locus_tag="JOX41_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAY6449018.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(18385..18771)
                     /locus_tag="JOX41_001263"
     CDS             complement(18385..18771)
                     /locus_tag="JOX41_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449019.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(18918..20588)
                     /locus_tag="JOX41_001264"
     CDS             complement(18918..20588)
                     /locus_tag="JOX41_001264"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HAY6449020.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            20771..21004
                     /locus_tag="JOX41_001265"
     CDS             20771..21004
                     /locus_tag="JOX41_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HAY6449021.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            complement(21103..21534)
                     /locus_tag="JOX41_001266"
     CDS             complement(21103..21534)
                     /locus_tag="JOX41_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HAY6449022.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            21613..22026
                     /locus_tag="JOX41_001267"
     CDS             21613..22026
                     /locus_tag="JOX41_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HAY6449023.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            complement(22064..23212)
                     /locus_tag="JOX41_001268"
     CDS             complement(22064..23212)
                     /locus_tag="JOX41_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAY6449024.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(23334..23930)
                     /locus_tag="JOX41_001269"
     CDS             complement(23334..23930)
                     /locus_tag="JOX41_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAY6449025.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            complement(24130..26772)
                     /gene="alaS"
                     /locus_tag="JOX41_001270"
     CDS             complement(24130..26772)
                     /gene="alaS"
                     /locus_tag="JOX41_001270"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HAY6449026.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            27160..27591
                     /locus_tag="JOX41_001271"
     CDS             27160..27591
                     /locus_tag="JOX41_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAY6449027.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            complement(27636..28985)
                     /locus_tag="JOX41_001272"
     CDS             complement(27636..28985)
                     /locus_tag="JOX41_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAY6449028.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(29055..30218)
                     /locus_tag="JOX41_001273"
     CDS             complement(29055..30218)
                     /locus_tag="JOX41_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449029.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            30347..30670
                     /locus_tag="JOX41_001274"
     CDS             30347..30670
                     /locus_tag="JOX41_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449030.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            complement(30853..32202)
                     /locus_tag="JOX41_001275"
     CDS             complement(30853..32202)
                     /locus_tag="JOX41_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAY6449031.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(32271..33224)
                     /locus_tag="JOX41_001276"
     CDS             complement(32271..33224)
                     /locus_tag="JOX41_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HAY6449032.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            complement(33326..34516)
                     /locus_tag="JOX41_001277"
     CDS             complement(33326..34516)
                     /locus_tag="JOX41_001277"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HAY6449033.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
BASE COUNT         9952 a         7642 c         6120 g        11248 t
ORIGIN      
        1 acctaaaaat ttggatttca acgatagaaa cactgttttt tatgtaatta gtccaagatt
       61 tttctagact tttgctttac tattcggcca aattggtttt tcttcttttt ttcgttataa
      121 tgaatatact tatgaaaaga aatgaggaat gaaccatgtc ctttgatggt gtatttaccc
      181 acgcgatggt caacgaattg cgtgaaacgt tactatctgg ccggatctcg aaaatccatc
      241 agccttatga aaatgaaatc gtgctggtga ttcgttcacg cggcaaaaac catcgattat
      301 tattatctgc gcacccaagt tatgctcgtg tacagattac ccaaatcgat tatcagaatc
      361 ctgataatcc gcctaacttc gtgatgatgc ttcgaaaata tttggatggc gctattttag
      421 aagacatcga acaaatcgaa aatgatcgag tgatccattt ccactttgct aaacgaaacg
      481 agttgggtga tctacaaaat atcatattga tcgttgaatt aatgggacgt catagtacga
      541 tcgtcttagt taatcgagaa actggaaaaa tactggatgc gatcaaacac attggaagct
      601 ctcaaaacac ttatcgttct ttgcttcctg gtgtagaata tgttgctccg ccaaaacaag
      661 aggtcttgaa cccatttagc tccgagaaag aaaaaatctt tcagcggctt tcccaaactg
      721 aactagatcc aaaagcaatc caacgtcagt ttcagggaat cggtttcgat atcgctcaag
      781 agctgaccaa aagattactg gaacgtccta atgaaaagat ggttgtatgg gacgaatttt
      841 tctcagccat cagccatcag cctattccta ctttttacga aacggaaaat aaagattttt
      901 tcacaccgat tgcttatcag gtattgtccg aacaggcatc tgctgtaaca gcttatccaa
      961 cactcagtca attattagat agctattatc acgaaaaagc agagaaagat cgggcaaaac
     1021 aacaaggcgg agaactgatt cgaaaaatcg aaaatgaact aaaacgaaat aaaaataaat
     1081 tgaaaaaacg tgaacaaaca ctcaaagaat ccgaaaacgc tgagaattac cgtagaaatg
     1141 gcgaactact tactactttt ctgacacaag taccacgcgg cgcaaaagaa gttgttttac
     1201 ctaattatta tgaagaagat cggccaatca aaatagcact agatccggca ttgacaccaa
     1261 atcaaaatgc acagaaatat ttccatcgat accaaaagct gaagaacgct gttaagctga
     1321 ttggcgaaca aatccaagaa gccaaagatg aaatccaata tcttgaatct gtcttatctc
     1381 aactggaaat tgccggccca atggatatcg aagcaattaa agaagaattg acttcagaag
     1441 gatacctgaa aaagaagaac ttaaaaaaac aaaaacgtaa gaaaccatct cagcctgatc
     1501 aatacttttc ttctgacgga acgctcattc ttgttggtaa aaacaatctt caaaatgacc
     1561 agctgacaat gaagacagct aaaaaaaccg actattggct tcatgcaaaa aatatacccg
     1621 gttcgcacgt catcattaaa agtgacaagc cctcagatga aacaattaca gaagctgccg
     1681 agttagctgc ctatttttca aaataccgat actctgccca agtgccggtt gatcttgtac
     1741 aggtaaagca tatccgaaaa ccaaatggcg ccaagcctgg ttatgttatt tatgaaaacc
     1801 aaaagacgat tatcgtgaca ccagaagaag aaaaaattac agctatgaaa caaaacaggt
     1861 aatcaatgag tgtttctaga atcatatttg cgtactttcc cacaacagca attagttata
     1921 aattgtttgc tacaaaaaga ggagttgtga caaaattctg tcacaacccc tcttttttga
     1981 tcaacggtgt tcaataaaca gcgttctcat ctgcttttct tagctctgct ggtccagtaa
     2041 ccgagtaagc tctttgataa atctttgagc gatttcactg agcggacgtt tcgccgaata
     2101 aatgatataa aattcattta gttcgccttc tgccaaaggg attaaccgca agtgctcgcg
     2161 aatccctcca atcacaatac cagatcctga agcgtaagca tcagtttcaa gaacgatatt
     2221 catcaaagta cctcgatcac tcgtataaat cactgtttct tgatcaggga tctcgataag
     2281 gtcttcataa aaatacggga aattatttcc atcctgtgta aaacgaactt gaggataaga
     2341 taacaattct tctttggtga tctctgcgtg ttcagctaat ggatgtcctt gccttaaaaa
     2401 aatatgcgtt ttgaattttc caatgctgcg gccacttagc tctccttgtt gtaaatatct
     2461 tctgatacca gcttgattat gctcattcat ataaataatg ccgatctcac tgtgctgctc
     2521 tttgacttct tcgatcactc tcgctgttgt cgtctccatg atccgaaatt gtttgatctc
     2581 gtctttgaat tcctcgagta gctgtgcggt caaaggacct aagaaatcat aatgctgggc
     2641 agcgatcgaa aaattgtctc tcttttcact cgttagatag tgagtttcta atgtatcaag
     2701 ctggaccaat attttctcgg cacgatttaa gaagtcttgc ccttcttctg ttaaatatgc
     2761 ccctcgattc gttcgagtaa acagcgtgat ccctaactcg gtttctaatt ctttgatacc
     2821 agctgaaaga cttggctggg agacaaacat tttctttgcc gcttctctga aactaccatt
     2881 gtttgctaca gcgaccacgt atttcatctg ctgaatattc attgctcaaa ctcctcgaaa
     2941 taataaattt ctcttccatt caagggctgg attggtcggt tgttcggtcg agcatactga
     3001 ccatcgaagg ggagaagaaa ctcttggttc agttttccta catgatccat tacaaaccat
     3061 tggattggcc cgctggtagg cggagttgtc aatgagccaa tataatggaa atggcttttt
     3121 tgctccggaa agaacacatc cggatttacc caatgctcat gtttttctaa gttccaactt
     3181 tccccatttt cttgattata cagccaacct tcctgtacca ttagctggta catgacaccc
     3241 acaactagat tctctttttt gctgttcata tgaacaaaat gaaattcaat atcttcctgt
     3301 tttccgttga tgatatgttc agaaggcaag tggaaatgaa tatctgtcaa ataatagcgt
     3361 tctttcttga actctacata actgagttgg tcaaaaggta ctaaatgaat cgtgtttttg
     3421 aattccttgt cagtaaaccg ttgcttttga taatgaaagg aaagcgtgtc tccttctatt
     3481 ttggtttctt cccccttggt caaatgaata ggcgactgca atggaaattc cgcacctctc
     3541 gcaaaccaat cacataaact cgcccaattt tccggacctt tgtctccaga atagccccat
     3601 tcgacatcca tattcttttt caactatact tccccctgca tctcatatca tttttatttt
     3661 tcttctttct ttacaatcgt tgagacggtt tctaaaaacg cctcttttcc ataaaattcc
     3721 tggttcaata gttccggaaa tatctcttta aagaaatact gaacagaagg ccgatgttca
     3781 aagcttttaa tcgtagtcac tgcctcaatg aacatctcct tataaacttt ttccgggtta
     3841 tttttgatga tttcatcaaa agattcataa agaaggtcaa ccttatctga aatggctaat
     3901 agttctcctt ctacggtttc atcttttcct tcgaacaacc gacggcgata aacttcttgg
     3961 aactcagctg gaatctcttg gttgatgaat tcgtccgtca tcttttcttc aactgtttgc
     4021 agcatccctc ttaactcttt gcttgcgtat ttcaccggcg ttttgatatc accaataaaa
     4081 cgctctgtgt agtcatgatt caatgatttt tcatagagca gtttccaatc gatcggttgt
     4141 ccattcgctt cttcaatgtc tcctagaact tgcgcaatag atgctacacg atacgaatgt
     4201 gctgcaactg tatgctctgt atatttaaaa aatccaggtg cccttgtgat cgtctctaaa
     4261 ttgttcaatc ctaaaataaa ttcattcaac cccataaaag ttacctccct ttgagatttc
     4321 tttttccgaa tatcatatca ttaaataact gatattcgca acatttccgc tctttaccat
     4381 ttttgaaaca gctcccttac caaaaaatag agaaaatcta tatataatag aaaaaagaga
     4441 agagattatt ctcttctttc tgctaaccag tcttagaaaa atgaatttta aaaaaatcaa
     4501 aaactgatca cgatagaagt ttcttttcat acctgatgaa aagatgcttc tcgcaatcag
     4561 tttttggatt tttgctattc caattgatga ttctggagac acaaatcgga tttctctatc
     4621 ttcatcaagc gcgcttaaat ctgccaattt tcaggatctt ttttccattc ttttagcaga
     4681 gttaattctt gctcatcgat ataacgatct tctaaagctg cttcaatcaa tacagaataa
     4741 ttggtcaacg tcataagagg gatttcggct ttttcgaaat ttgcttttcc ttttggcaac
     4801 tcatacgtaa agatagccgc aacaccaagg atatccgcac cttctctttt tgctgcttca
     4861 gctgcttcca agacacttcc gcctgtagaa atcaaatcct cgatcacaac catcttctga
     4921 ccttcaaata tacgtccttc gatttggtta cctttcccat gatctttcgc cttacttcga
     4981 atatagacca ttggcaaatc cagtatttcc gctacccatg cggcatgagg gattcctgct
     5041 gttgcagttc cagcaatcac ttgtacttca gggtaagctt ctttgatttt gcttgctaat
     5101 ccttttgcga tctcttttcg gacttttgga tagctcatcg tgattcggtt atcacagtaa
     5161 attgggcttt tgattccact tgcccatgta aaaggattac ttggatttaa aaatactgct
     5221 tcaatttcta ataagtcttt tgcgatactt tgttcaacat tcattttagg ttagctccat
     5281 tctgtttgaa tcgtttgata tgctttataa ggattagttg actgagtgat tggtcgacct
     5341 ataacgataa aagttgagcc gatctttttt gcctgagaag gtgtgactac tcttgtctga
     5401 tctcctgcga ctgttccttc tggtcttata cccggagtta agcaaacaaa ttcgtctcct
     5461 gccatttctt tgatcgcttc tacttcccaa gcagaagaaa ccacaccatc taatcctgct
     5521 tttttggcac agctagcata atggatcaca cttttttcta aagaaacttc gattagttga
     5581 tcggcatgca tttcttcttc acttgtagaa gtaagctgag tgatagctag aagtagcgga
     5641 cgttttccac cttctggagt cccctcttct aatcctcgca ttgccgcctc catcatacga
     5701 ataccgccag cggcatgaac acaggtgaga tcaacaccaa gctttgccaa tccccgcatt
     5761 gctttttcga ccgtattcgg aatatcgtga agtttcagat ctaaaaatac attatgacca
     5821 gcctctttta gataacgtac gatttcaggt ccttcttggt agaacaattc cattccgatt
     5881 ttcacaaaca atttttcttc tttcgggaaa aatcgaagaa agtcttctac ctcttgccta
     5941 gttgaaaaat ctaatgcaat aattggtcgt tggtctagtt gattcatcgt tcacgttcct
     6001 ctctcacttc tttgattaat ctttccagcg attcgatgcc tagttcgctc attcgcacag
     6061 ggagctcttt aattagttta ggacagatat acggatcggt gaaattcgcg gtccctatag
     6121 ctacagcact tgctccagcc ataaacatct caagaacatc atccactgtc tgcacgccgc
     6181 ccatcccaat gattggaagg ctggatatac ttgctacttg gtgaatcaaa cgaatagcga
     6241 caggcttgat tgctggtccg gagagtccac ctgtttgatt ggctaaaatc ggttttcttg
     6301 tcttaaggtc aatccgcata ccaagaagag tattgatcat cgtaaaccca tctgcccctc
     6361 cagcttcgat tgcctgagcg attggaacga tgtctgttac atttggggac aatttgacat
     6421 agacaggaac agaagaaact ttctttactg cttgtgttaa ttgaaaagca acatcagaat
     6481 ctgttccaaa agcaattccg ccatgtttga catttgggca agaaatgttc agctcgattg
     6541 ctttcacatt tggtgcttcg ccaattttgc tacaaacttc tacatagtct tcttcacaag
     6601 caccagcaac atttgcgatg atgggtaact cattgtactc ctctaattct ggaagaagtt
     6661 tatgcataac aacgtctaga ccaggatttt gcaaaccaat tgcattcaac atgccagatg
     6721 gtgtttccgc cactcttggc gtgggattgc caaagcgggc atttggagtc gttgccttga
     6781 ccatgatcga tccaagctga ttcaaatcat agtattttcc gtattctttg ccaaaaccga
     6841 aacagccgct tgccggcatg ataggatttt ttaattctag gccaggaagt ttgaccgcta
     6901 aaggattctc attcatataa ttacctctcc tattttaaaa atcggtcctt cgtcacaaac
     6961 tttcacactt tttgttcctg tttcatcttc cggcgtatga caaacgcaag catagcaagc
     7021 ccctatccca catgccatgc gggattctaa tgataactgg acattttgat gcgaagaaaa
     7081 cagctgttcc actgtcttca ataacccgtt tgaaccacat gcaaaaacag ctgtaggttc
     7141 cgtcttcgtt cctaacaata aattaccgac atttccgtgc ataccgtatg ttccatcgtc
     7201 agtagcgatt cttgtttctc ctagacgatt aaattctttt tcataataaa cgacttcatg
     7261 tgtggcaaaa cctaaaaaat gcgttggctt aattcctttt tcgactaact gttttgataa
     7321 ctcatataga ggagggacac cgattcctcc accgattata aatacttcgt ctcctgtatg
     7381 aagattggac aaatcaaaac cattgcctaa aggacccatg acatctaaat ggtctccggc
     7441 agaaagagta gagaagactc tagtcccctc accttccacc cgataaatga tacggcaagt
     7501 atttgtttcg tggtcgatat gattcaagct aatcggtcgg cgtaatagca agtctgcacg
     7561 cggcacgaga atatgcaaga actgtcctgg ttgctgcatt tcttttacta gatcaccttt
     7621 caatgtcatt tcaaaaatct ttggtgccag ctgtttttgc tgaacgattt ccatcatttc
     7681 ttgtttcatc tgtcccctcc tgcaacggtt tttcgtcttt ttgtcttaac atgtgctcgc
     7741 cgttaaatag ggttagttga aaaagcacgg gattccatca ctcgaacgat cgcatctgct
     7801 gtgtctaaag aagtaaacaa tggaatacca tgttcaactg cttctcttcg gatgatgaaa
     7861 ccgtctttag aagcatttcc ccgatcttta tcaatcgtat tgacaaccac ttgtgtttta
     7921 ccatctctta ttaagtcgac tacatttttt tctgctgctt cctcagaaat tttcgctact
     7981 gtttcaacga ccagaccatt tttttcgaaa taagcagctg tatgtttcgt tcctatcaga
     8041 ctatagccaa tttctgtaaa acgtttagct aattctagtg cttcttcttt tgtttcgtcc
     8101 gcaatcgtaa ataatacggc tccatattca ggcaagtgta atccagaagc ttcgaatgcc
     8161 ttgtacaaag ctttgtctaa ttgtctgtca gatcccatta cttctccagt cgatttcatt
     8221 tcaggcccta agtaagtatc aactttctgc aatttcgtaa aagaaaagac aggtgcttta
     8281 acatgaactt cttttgtttc tggataaagt ccgttttcat aaccaagtgt ctttagtttc
     8341 tctcccaaaa tagctttcgt cgcaatttgt gccattggaa ttcctgtcac cttacttaag
     8401 aatggaacag tccgacttgc tcgaggattg acttcgatca cataaacctc attttcatgg
     8461 atgacaaact ggatattcat catcccgaca caattcaaac ctaatgctaa gcggatcgtg
     8521 taatcttcga tcgttttctt gatcgattca gataatgttt gaggtggata cacagccatt
     8581 gaatcccctg aatggacacc agcacgctca atatgctcca tgatccctgg gatgagtact
     8641 gtttcaccgt cacaaatcgc atccacttcg cattcaccac caagcaagta acggtccact
     8701 agtactggat gttctggaga tgctttcaca gcatgttcca tgtaatcttc taaatctcgc
     8761 tggttttcaa cgatttccat cgcacgtccg cctaatacat agcttggacg aacaagaact
     8821 ggataaccaa ttctcgaagc gataaccacg gcttcttctt tacttgtagc agtatcccct
     8881 aaaggttgag gaatatccaa ctctttcagc gcttgctcga ataaatcacg attttccgca
     8941 cgatccaagt cttcgatcgt tgtccctaag atttttacac cagcagcagt caaaggttcg
     9001 gctaagttga ttgctgtctg accaccaaat tgaacgatta ctcctatcgg ctgttctagc
     9061 tcgatcacat tcatcacatc ttcgaaggtc aatggctcaa aatataattt atccgaaata
     9121 gaaaagtcag tcgaaactgt ttcaggattg ctgttcatga tgattgcttc gtatcctgcc
     9181 tgctggattg ctttgacaga atgcacagtc gcatagtcaa attcaacccc ttgtccgata
     9241 cggataggac cagatcccag tactagaatt gagggctttt ctgatcgtga actttcattt
     9301 tcatattcat aggaactata aaaataaggt gtttttgatt cgaattccgc tgcacaagtg
     9361 tcaaccatct tatatacagg aatcaaatca ttttcttttc tcatctggcg aacggcttct
     9421 tcgtttattt cccacagctc cgccactttt ttgtctgtaa aaccgttttg tttcgctgtt
     9481 ttcaatatct tgtcatccaa cggctgctgt ttcaactgct gttcgatttc tacgatatgc
     9541 aacagtttat ctaaaaagaa taaatcgatt tttgtcaaat ccgctaattc ttctatggtg
     9601 taccctcttc taatagcttc agctacataa aacaggcgat catcttgtgc tcgaaccact
     9661 ttttggatta ggtcatcgtc cgtgatgtct gccaactcag gaagttcgat atggtgtgta
     9721 ccgatttcta aagaacgcac agctttcaat aaagactctt cgatattccg accgatagcc
     9781 atcacttcac cagttgcttt catctgcgtg cctaaaagcc gttctccgtt ttcaaactta
     9841 tcaaacggcc agcgaggaat tttagctaca acataatcta atgcaggttc aaattctgca
     9901 aaagtcgttc ctgtaacagg atttttcatt tcgtctaatg ttaatccaag cgctatttta
     9961 gcagctagct tagcgatcgg atagccagtc gccttacttg ctaacgcaga tgaacgagaa
    10021 acacgcggat tgacttcaat cacataataa ttaaaactat gtggatcaag agcgagttgg
    10081 acattacagc ctccctcgat cttaagtgct cgaataatcg aaagagaagc atcacgaagc
    10141 atttgatatt catggtcaga caatgtttga ctaggggcaa atacgataga atcacctgta
    10201 tggataccca ccgggtcaaa attttccata ttgcagacaa cgattgcatt atcagccgaa
    10261 tctctcatca cttcatattc aatttcttta aaacctgcaa tacttcgttc aatcaaacat
    10321 tgggtagcgg gggaaagact taatccattt tctgatacga tacgtaattc ttcttcattt
    10381 tcacacatac ctccaccagt tccgcctaaa gtaaaggctg gacgaacgat gacaggatag
    10441 ccgattttat ttgcaaaatc tacagcttct tctactgtat tgacgatttc agactcgggg
    10501 attggctgat tcaattcttt catcaactgt ttgaatagat cacgatcttc tgcttgatcg
    10561 atcgcagaaa gctttgttcc tagaagttct atgttcaatt cttctaaaat acctgatgct
    10621 gccagctcca ttgccatatt gaggcctgtc tgtccgccta aagttggaag gagagcatct
    10681 ggacgctctt ttcgaagaat ccttgataca aattcaagtg tgatcggttc gatatatact
    10741 tgatctgcca cttctttatc cgtcatgatc gtcgcaggat tagaatttac taaaaccact
    10801 tcatatcctt cttcttttaa ggcaaggcag gcttgtgttc ctgcgtagtc aaattctgcg
    10861 gcttgaccaa tgatgatcgg accagatcca atcaccataa ttttcttgat atctgtacgt
    10921 ttcggcatct gtttactgct cctttcctgc gtccatcatt tccataaatt catcaaataa
    10981 atgtagtgca tcatgcggac caggggcagc atctggatga aactgcacac tgaaagcggg
    11041 ataatctctg tgtttgactc cttctactgt tccgtcattt acttctacat gagttacgat
    11101 gagtttttct ggatcaatcg tggcttcatc gactgcatag ccatgatttt gagaagtaaa
    11161 atcaattctt ccggtcgcta cttctcgtac cgggtgattt aatcctcgat gtccgaattt
    11221 cattttatag gtatctgcac cgttggctaa agcaaataac tggtgaccga gacaaatacc
    11281 aaaaatcggt acttttcctt ggattttttt gatcatttcg attgcttctg gcacatcttt
    11341 tggatcacca ggtccattcg tcagcatgac tccgtctggt gatagcgcta aaatcgtctc
    11401 ggcatctgtg ttatagggaa gtactgtgag gttacagttt cttttactca attctcgtaa
    11461 aatactatgt ttcaagccga agtcaatgac aatgactttc cgacctgttc ctggacttgg
    11521 ataaggtttg ttagttgaga cttgctgcac ttgattggtt gctagaacgg ttgctttcag
    11581 ctgatcaaat gcatgttcga aggaatctcc agcatcaact atactagctt tcatcgttcc
    11641 gacttcacgg attttgcgag taagggcgcg cgtatcgata cctgatattc caggaattcc
    11701 tttttgtttc aaaaatgaat ctagcgtcat ttggtttcgc cagtttgaag ctacacgtgc
    11761 atgttctttt actactactc ctttgcatgt tggagaaatc gattcataat catctctatt
    11821 taccccataa ttacccacca taggataggt aaatgtaatg atttgaccgt taaaactttg
    11881 atcagtgata gtttcttgat aaccagtcat acttgttgta aaaacgattt ctccgaagac
    11941 actagcatct gcaccaaaag cctttccttc gaaaactgtt ccatcttcta atataagcaa
    12001 acgttccata cttttattct cccttctgcc acacaagttt tccgttgaca aaagtcattt
    12061 gtgtttcgcc ttttactttc cagccgataa aaggtgtatt ctcccctttt gataaaaagt
    12121 cttctttatc gatcgtgcaa gtttgtgtaa tatcaaaaac tgctacatca gcgggggcac
    12181 caaccgttag cgttcctgca ttcaaaccaa aaatctcagc cggtttaact gccaaccaat
    12241 tgatcacttg ttccaacgtg aatcgaccag tttctacaaa atgagtatag atcagttgaa
    12301 acgctgtttc gcttcctacg ataccaaatg gtgatttcat gaaactttgg cttttttctt
    12361 ctaatccatg gggggcatgg tctgtagcga tgcaatcgat cgtaccgtca agcaagcctt
    12421 cgatcaaagc ttctctgtcc tcccgtcctc ttagcggcgg gttcattttc caaaagccga
    12481 aatcttcggg aatatcttcg tcgatcaaaa taagatgatg gggtgaaact tctgctgtta
    12541 cgtggattcc tgcttttttt gcgtctctga ttacacggac actttcttta gtagaaacat
    12601 ggcaaacatg gtaatgaaca ccagttgctt cagctagcaa cagatctcta gcaatttgag
    12661 aagactcggt tacgcttaag atcccgggaa gaccaagttc ttctgccttc ttgccagcgt
    12721 gcataacgcc gccaaataat aaagattcat cttctgtatg ggctactagg gctttattgt
    12781 tttttgcagc ttctttcata gccagataca tcgtcccagc tgtttggaca cctacaccgt
    12841 catttgtgaa agcaaaagca ccttcttcaa tcagtgcttc ttgatcaact aatttctcac
    12901 ttcgcagatt ttctgtgatt ggcgcatact gcaatacctt cacaactgca tcttttctaa
    12961 tgatgtcata tacttgtctc agcttttctg ccgtatcagg tacaggattt aaattcggca
    13021 tcgcgcatac agtagtgaaa ccgccacgag cagctgagcg agtcccagct tcgatcgtct
    13081 ccttgtatgt aaatcctggc tctctcaaat gaacatggac gtccactaaa ccaggtgtga
    13141 tcaattgtcc ctttgcatca aacacttcat caaattcggc ttctgagaat cctgtaccga
    13201 ttgctttgat tcgcccatct tctatccaaa tttctgctgg tgtcgtcata ttttttcgtg
    13261 tattgatctg accgttttta atgagtgttt tcattttttc atcctcctat aattacgctt
    13321 ttccatttag cactgcttct aagattgcca ttctgacgaa tactccattg ctcatttgct
    13381 gaacgatccg cgactgtaat ccttccacta atgaatcagc taattctaca tcacggttaa
    13441 ctggtgctgg gtgcataatg attgcatgtt tttgcaactt cttcgcacgc tcaactgtta
    13501 acccatgttc ctgatggtag ccttcttttg agaaactttc ttttccatca tggcgttcgt
    13561 gttgcacccg aagcatcatc atgacatcaa cttgatctag tagttcatcc aatggcatat
    13621 aatgtccgta cacttcgaat tcatcgtcgt accattctct aggacctgag aagaatactt
    13681 gtgcgcctag acgttttaac atctgcatat tggatttagc tacgcgagag tgagtgatat
    13741 cacctacgat ggcaactttc agaccttcaa aatgaccaaa ttcttcataa atggtcatca
    13801 aatcaagcaa gcattgggtt ggatgctgtc cgcttccgtc tcctccattg ataatcgaac
    13861 actggattgt tttactttgt atcagttcgt cataatagtt ctcatcacca tgacggataa
    13921 ccgctacgtc tacgcctaat gctgacatcg tcagtactgt atcgtatagt gtttcccctt
    13981 tttggacaga gcttgtgctt gcttcaaatt caatcacttc tagccctagt tttttctccg
    14041 ctacatcgaa gcttttatgt gtgcgagtac tattttcgaa aaagaggttt gtagcaaagt
    14101 actggcgctt ttgcggagtc caattagcac cttgcttgaa ttcctgccct ctgcggatca
    14161 agcccataac ttcttgatca gtaagtgcct caacggtcaa taaatgcttt aagctgatac
    14221 gttctgattt gatgatcata atgtttcctc cttagttttc ttcgcttcgt gaagtttctg
    14281 gtaagataag atttaaaatg atgccaagta cagttgctaa tgccattgcc gacaatgtaa
    14341 atgtgcctac ttcaaagacg agtccgccaa ttcctactac taagataact gaagcaatca
    14401 acagattttt ctttttatca aaatcgattt tgttctcgat taaaatcttc attccacttg
    14461 cggcaattac tccaaataag ataaaactga ttcctgagat gactggtcca gggatactta
    14521 aaatcaaagc gcttaatttt cctacgaatc ctaaaatgac tgcaaatact gcagctccac
    14581 cgatcacaaa cacgctatgg acacgtgtga tagccagaac accaatgttt tcaccgtaac
    14641 ttgttacagg aggacctccg acaaaggctg ccacgatttg tgctaatcca tcacctgtca
    14701 acgtcttatg aagacccggt tcttcaaaga aattacgttt agttagttta ttcaatacca
    14761 taagatggcc gatatgctct gtcatcgtca caaaagcgat gggtgccatt gttgtgattg
    14821 ctccaagata tagctttggt tcatattgta caaagggaat ctcaaagtta ggaacagcaa
    14881 accaggcagc gtctacgatt ggcttagtat ccacgattcc aaacagcaag gctacgatgt
    14941 atccgctaat aatacctagt aaaatcggaa tcaatccgag aaaacctctt agccacatgt
    15001 tgaagaaaat tgttaatcct aatgtgatca gcgctacagc aatatacttg aaatcatacg
    15061 tgccctgatt atacatagca tttgttgctg catttgccgc aagtcccaac ccgataacca
    15121 tgatgactgg accgacgacg attggaggca agattttatc cagccatgct gaaccgatct
    15181 ttttgatgat cagcgcaaca atcaaataga ctaatccagt tgtgactgct ccttgtgcaa
    15241 tcgctggata accatctgtt ttcatcaaaa gctgcatcgc tgcaatgaaa gcgaagctgc
    15301 ttcctaagta cgcaggtatc tttcctttag tagtaaataa gtacaccaat gtacctagtc
    15361 ctgaactgac tagcgcaata cctggatcga tacctactaa gatggggact aacacggttg
    15421 ctccgaacat cgtgaacaag tgttgtaaac ttaatcctac ccaatgtcct ggggttgggc
    15481 gatcgtggat atctaacacc acgtcatcat tatgaaatcc ttttttctcc gacatgtttc
    15541 tctctcctct aatcttcctc tttcaaaatc atgatgcgat cttgtccatc aagctcttgc
    15601 atctctacta aaatctcttc cgcccgagat gttggaatgt tcttcccaac ataatctgca
    15661 cggattggca attctcgatg cccacgatcg accaggactg ctaatgaaat ttttcttggt
    15721 ctgccaaaat ccattactgc gtccattgct gctcgaatcg ttcgtcctgt atacaaaaca
    15781 tcatcaatca aaataacttc ttttccttct aaggaaactg ggatgtcaga agaatgaagt
    15841 tccggttctt ctggattttc ttttttgtca tctcggtata aagtgatatc cagttctcct
    15901 acaggaatat cgatatcttc tagctgcttc aggcgttcgg caattcttga tgcaatgtag
    15961 attcctcgtg ttttgatacc taccaatacg atatcttgga tactatggtt tctctcgata
    16021 atctcataag taattcgagt caatgctcgc ttcatggtta cctgatctac tacttctttt
    16081 gcttgcattt tcattccccc tacttttttg cataaaaaaa ctcctgccct aagaggacag
    16141 gaggaatgtt tagactgagc gtatactgat acactgatag ctatactatg tcaatgagca
    16201 atctacttat ggcgcaccat acgtatcctt gctcccaccc ttcttagcct cacgggacta
    16261 aacttaaagg aattctatta agttttatgc tttcgttgtt aattactata ccgttatcta
    16321 aattaaaatg caatgttttt tcttaatttt tctaaagttt tttcaaaaac ttctggaaga
    16381 ggtgcttcaa agatcatctt ttcgtttgta gtcgggtgcg taaaacctaa catttgcgca
    16441 tggagaaact gaccattgcc tttcaaagtt ttcttcggtc cgtatactgg atctccagct
    16501 aacggataac cgatatactt catatgcaca cggatctggt gtgttcttcc ggtttctagt
    16561 tttaattcaa ccagagtaaa tccttcgaaa cgttccaata cagtaaaatg tgtgacagcc
    16621 gacttcccat cttctcttat cgcctgcatt ttccggtttt ccttcgaacg gccgattggc
    16681 gcattgatgg ttcctttttc gtgaggaatc tctccatgga ctaaagcaac atatttgcgc
    16741 aaagaggtct tatcttttaa ttgctgagct aatgattcgt gtgcctggtc atttttggca
    16801 accattagca gtccggaagt atctttgtcg attcggtgaa caatacctgg acgaataacg
    16861 ccgttgatcg tagaaagatc cttgatatgg tacatcagcg cattgaccat tgtgccatgc
    16921 gtatgacctg ctgaaggatg aacgaccatt ccttgaggtt tgtttatcac cgctacatct
    16981 tcatcttcgt aaacgatcgt caacgggata ttttctggga ccacatctaa tgtttctggt
    17041 tcggggatca agacagtaat ctcgtctcct tgttttactt tgtaatttgc tttgactggc
    17101 tgtccattga cagaaaccgc tccatttttc agccacagct gaatttgcga acgactgtaa
    17161 tcggtgaata aattagtcaa tactttatcg atcctaccag attcatggtg aatcgtcgtt
    17221 ttaagttctg tcattttttt ctttgatcct tttcatctaa aataatataa attaacatac
    17281 aaatcactcc acatacaagt gtcacatctg ctacgttaaa aatcggaaag ctcataaaat
    17341 ctgtctggaa catatctact acatagccaa gacgaatacg gtcgataaaa ttgccaatcg
    17401 caccagctag aatcaaactc aatccaatca tgaaccagcg attacctttt tcacgatttt
    17461 taatcatcaa tgtgagaatc acaacgactg caatgagtgt cactatagta aagaaccaca
    17521 tcttcccttc tagcatactc catgcggctc cagtgtttcg aatatgattc agtgacaaaa
    17581 tacctggtat aagatttttc gtctctccaa gcgctagatt atcagtgatc caccatttga
    17641 ccaactgatc cactcctact agcaaagcgc tgaatatcca ataaataatt aacaaaaaat
    17701 caatcctttt ctatttgttt ataaatatca cgaggtcgta cgatcccgag cagattacca
    17761 tcgggattcc catctttagt gataagtacg gcttccaaag tcccttgctc acgaaacatc
    17821 gcttcaacct cgtaaatatg tgttttagct ggaacaaaat gataatttgt gtactttccg
    17881 ttttggatga tcaaatccaa cgctcgttta tttgttaaat caaccggacc tttttggctt
    17941 tcttttgcta gccaaaaccc gatattacgt aaagtaatca atgctacaaa ttttccttta
    18001 ttgtataacg gaaattgtga ataccttttt tctgctacta tctttaacag ttcaagtaac
    18061 ggaagatctt gttcaaaacc tgttacacgt tttgcaaatc gaggcagcac ggtttcaggc
    18121 tgaatcagtt cttgttcgat cagctggatt cgcttgactg tccaatcatt tggctctgca
    18181 atgacaaaat cgactgcgat ccgatcatgg acgatcgcat tccttaactg agcaagctgt
    18241 aaaagatcat cttcgtattt tctgatcatt aattgttttc tttgagctag gcgtctgaca
    18301 agttcggtaa atcccatatt tcgtgcattt cccatctcgt ctctcatcca tttttcgatt
    18361 cgattgaaac tgattaaaaa aagatcagag tttgccataa ttttcctcct tgatcaaata
    18421 tgcccggttt tttatataga aaaagaacgc aatcaacaca ataactgcaa aaaaactgaa
    18481 aaataaattt tgtaggaaaa cggcccccaa cccagttgct agaaataaaa acggatagat
    18541 ttgaagaatc aagtaattca ttgtgatcac ataagcaggc tttgcttctt tcactgtata
    18601 aacggggctt tttagccaat aaaaggtgac ctgcatcgta aagggcactt ccagatcaag
    18661 cgttatcttt tgttcatgac tgagaacact gcgtttttca ttgttgattc ttagctgaat
    18721 cgagctaccc ataccgtaaa aaccggtttt tcttataaat gtcgttttca tcataccctc
    18781 ctattatgct ttagtatagc tcaaaataca ataaagaaaa agaatgatcc tagtgtaaac
    18841 aaaattaatt ccctatcgtc taaaaaaaga agctgtagtc aaaatacagc tccttcgatg
    18901 gtagattata atcaagctta aaacaatccc aacacttctc cgtcatttgt cacgtccata
    18961 ttcaatgcag caggtttttt aggcaaacca ggcatcgtca taacatctcc agtcaaggct
    19021 actaaaaatc ctgcccctaa ttttgggatg atttcgcgga tcgtgatggt gaaatcttcc
    19081 ggtgcaccta gcagtgaagg atcatcagaa aatgaatact gtgtttttgc catacaaatc
    19141 ggcagtttgt cccatccatt cttcgtaaac tcttctattt gtttttgcgc ttttttgctg
    19201 aaaacaacac catttcctcc gtaaattttc ttgacgattg tttctgtctt ttcttgtatc
    19261 gtttcttcta ggcggtataa tggcttgtaa ttagcttctt ttctatcaat caatcgtact
    19321 acagcttttg ctaaatcaac gccgccttct gctccatctg cccatacact cgctctcttg
    19381 gcaagaatcc cctgattttc acacaagtgc tccaacagtg tgagttcatt gtctgtatct
    19441 gttacgaatt cattgattgc gacgatcaca ggtagctgat attgttccat attacgtata
    19501 tggcgcttta aatttgcaaa acctactttc aaagcatcaa gattctcatt tttaagttca
    19561 tcttttttca ttccgccatg cattttcaat gcacggacag tggcgacaat caccacagca
    19621 tccggcgctt ttttcaagtt aggtactttg atatctaaaa atttctctcc gccaagatct
    19681 gcaccaaatc ctgcctctgt gacaacgtaa tctgctaatc tcaatgctgt cttggtagct
    19741 aaaatactat tgcagccatg agcgatattg gcaaacggtc ccccgtggac aaaagctggt
    19801 gttccgtaaa ttgtttgtac aagattcggc ttgattgcat ctttcagcag taatgccaga
    19861 gcgccttctg ctttcaagtc tccagcagtc acaggctgac ggtcaaatgt atagccgaca
    19921 acgatccttg caagacgagc ctttaaatct tcaaggtctg ccgcaagaca caagatagcc
    19981 atgatttcgc tggcaactgt gatatcaaac ccatcttctc ttggaacacc ttggattggc
    20041 ccacccaagc caacaattac tttacgcagt tcacgatcat tgagatcgac tacccgtttc
    20101 caaatcactc ggcgggcatc gatgttcaat tcatttcctt gatgaatatg attatctaaa
    20161 agagcagata atgcattatt agctgttgtg atagcatgca tgtcaccagt aaaatgcaag
    20221 ttgatatctt ccataggcaa tacctgtgca tatcctccgc ctgcagcacc acctttgatt
    20281 cccatcacag gaccaagtga gggttctcgc aatgcaataa cagatttttt attgatttta
    20341 ttgagcgcgt ctcctaaccc tacagtgatc gttgactttc cttcgccagc tggtgttgga
    20401 ttgatggaag taactaagat caaatgcccc tcagcgttat cctttgatcg attgattcca
    20461 gaaaaattga ttttcgcctt atatttccca tacagttcca aatcgtcttc cttaagatct
    20521 aatttactag ccacttcaac aatcggttct agctctgttt cttgtgaaat ttgcagatca
    20581 ttcttcattt gattacccct tttcacgaac tttattcaac aaaatatctt ctttgttaag
    20641 atatgccaat tatacctttt tttattcaga aaaaaaacat aaaattacag gtttttaatt
    20701 tatttgacgt acttataaat actctttata atgaaggcta tgatcagact ttagaaaggt
    20761 cgtgagtgct ttgaccacag gaattgtaaa atggtttgac aacaaaaaag gatacggctt
    20821 tatcagttat gatgacacag aagaaatttt tgtacatttt actgcgattg aagaagaggg
    20881 attcaaaact ttggaagaaa atcaagtggt cgaatttgag atcatcgaag ggaatcgagg
    20941 aacacaagct gcccatgtca agaaaggcaa cgttcagact accgatacta gtatgcatga
    21001 atagataaac aaatagagtg agacgctaaa cgggatgaac cgtacgtctc actcttttct
    21061 tttcctgtaa aaattcgttt ttttaggttc tgatttttaa aattagcttt ttcttttttt
    21121 cgtataagga taaggaattg attctgattt gggtccgttt ttttcaaaat gatcaaaaag
    21181 gactacttga tctttttttc gcatcatgaa aacagatggg gctttctcat cttgcaacat
    21241 catttgcacc ccagtattag ttggcgtcaa agatcgaatc tgtccgacag atatttctcg
    21301 gtctttccaa aaagcagcat aacgtataat cacagagttt gattttaaaa taaaagaacg
    21361 ccgcaaacct agaaatagaa aaacaagaaa aatacctaaa acaaaattgc ttttccaata
    21421 aggacctgtg ttttctaaag aaagaatcag actaaaaaac agaatgatca aggtcaatga
    21481 ccaatagatg atcgtatgtg ccagttcagg ctgccatcga atattttttt tcattctcta
    21541 acctctcacc gattcagtaa tgatataatc ttaccataac attagtttga acaaaaagga
    21601 gaatctcttt ttatgttaaa agtatacatt gatgcctcta caaaaggcaa ccctggtcct
    21661 agtggaggtg gaatcttgat tgtctatcaa ggtaaacaag aacagctatc tatcccgctt
    21721 tctataggga caaaccatca agcagagttc gaagtctttt taaaaacttt agaatttcta
    21781 aagaaaaacg acttacagaa tgaaacgatt ttctgttttt cagacagcaa aacactagtt
    21841 tctacggtcg acaaaaacgc aacgaagaac gagctcttcc ttccctacct tcaaagaatc
    21901 caagaacttc tatccgaatt ttctttattg atcctgcaat ggttgcccga aaacaaaaat
    21961 aaaggagcag ataatcttgc acgtcaggct ctccataaac aattaaaaga aaaaaagact
    22021 ctttaaatta aaaactttaa ggagtctttt tatagtttct catttaatat aaaagataat
    22081 tgtgatcaaa cgtaatttcc aattggtaat ctccgatttt ttcttctatt tgactacgta
    22141 agattctttc tagttctgta tcaacaaact ggaatttctc agggaccact acatcaaatt
    22201 gcagcgtttt tccttgatga attactctaa aatcatgaat attaagccct gtacctgttt
    22261 caagaagaat ttgctttaac tgccgcaaga tattatagta tttttcgtta tcaacaggca
    22321 ttggatccaa gtgacagaca agttccacat ccaaagactt tttaaagtct ttttctatca
    22381 gatcaataat cttatgagcc acattcaaat tcattgattc atctacttcg atgtggactg
    22441 atgcaaagcg tttattgggt ccatagttat gcaccaataa atcatgatag ccaagtatat
    22501 catcgcaagc atttaaatgc tcttccattt cttcaatctc tgctggcgtt gggcgacttc
    22561 ctaatagttc gtatacaaaa tttcgaagca tcgtcaatcc actataaagg atatataatg
    22621 ctaaagcaaa acctatatat ccatcaatac gccatccagt tacccattcg attgctgctg
    22681 aaagcaatac agccagtgta gtaaagacat cattataact atctgttgct gtagctctca
    22741 atgtttcaga atcaatggat tgcgcaataa cctgatacat tttgccttgt gcaaatttca
    22801 aaaagatgga aatgattagg acaaaaaaga cgatgggtgt taaagagaca ttttctggat
    22861 ggatgatttt ttcagcagaa gactctaaaa attgaaatcc tacataagta atgatgatcg
    22921 aaacaaataa cccactgata tattcgaagc gttcgtgtcc ataaggatgt tcctgatctg
    22981 ctggctttgc agcaatttta aatccgatca aagtcaatat ggatgaagca gtatctgata
    23041 gactgttcac tgcatcagcc ataatggaga cacttcctga aaaaagcccg atcattagct
    23101 tagagacaaa caagatcaga ttcgtaacca atcctaagat acccgctagt actccttttt
    23161 ttgtccgctg ttgcggtatt tgtttctttt tttcttcttg tttcttagcc aagtttttta
    23221 ccccttctag tttgcttgtt gctcaggtaa aaagatggag aggacgattg ttttcctctc
    23281 ctctcttcct ttttctatct atcgtgcgtc ctattactat taaaagatgg tcattattct
    23341 ggtttcaacg gtgttgctgc aaataacgct tttgctagta atggtgttat gattcccgca
    23401 cctattgctt ctggtatccc attgattgct gcaacccctg ctaaggtttt aaataaaaga
    23461 gcagagtcta caccataggc atctgccgtt gcacctgtat aaaataatcc catgaatcct
    23521 aacactaaga ctgtattgac caatgaaccc agtacccctg caaaggctga gctgatcgtt
    23581 attgatttat ttttttgata aatccagtgg aaaaccaagc ctgctactaa gccaacaagt
    23641 actctgggaa ctaccgagat aatcggattc gtgaacacta atgtatcaaa tggcgttgtt
    23701 ggcatggcat aggcacgaac aattgtagcg attccccaaa acaagccaat caccatgcca
    23761 tcttttgggc ctaatactac tgcagcaata attactgtga tatggataat tgttaaacta
    23821 atgaatccta atggaataaa ccccagccaa ggaaccatcg cttgtacgat gatgattgct
    23881 aacaagatcg cacgtaagac tagtcgaaag gtcttatttc tactattcat tttttcaccc
    23941 ctttttattt atactaatcg taaaaatttc tgtcactttc gtcaactaaa gaccatccga
    24001 atccgaccat ttgattagat gcgccatcca attgaaaaaa gtatgagggc aagacttgtt
    24061 tgtcttcgcc cccataatca tgtttcgttc aatgtttgaa cttttgtttt tctgtcaaac
    24121 gtaaacgccc tattgttgcg caacccattc tttcgcagct ttaagtgcat ctggaatacc
    24181 agcaggattt ttcccgccag cttgtgccat gtctggacgt ccaccaccgc caccgcctac
    24241 tttcggtgcg attgctttaa tcaagtcgcc agcttttagt ccagcttcat ttgattcttt
    24301 cgtcattgcc gctagcagac tgacttttcc ttcttgttcg tttgctaaaa caagaatatc
    24361 tgaaatattt ttttgtttcc attggtcagc taattgacgc agctgattca tatctttcac
    24421 ttttacttgt gctgcaatga ttgtttttcc attgatcgtt tctggatctt tgaatacatc
    24481 accagcttgt tgattcgcta acttgctagc taattgttca ttttcctttt gtagctctct
    24541 tacttgctgt tgcaattgtt ccgcttttga aacaacttct ttcaattgag gtgatttaac
    24601 aattgttgct acttgtttta gttgtttttc ttcttcttca agtagttcgt acgcttcttt
    24661 acttgttaca gcctcgattc gtcgcacgcc tgcaccaatt cctgattcag aaacgatttt
    24721 gaagattccg atgttttctg tatttgctac atgtgtgcct ccgcacagtt cgattgacca
    24781 gccgccaata tttactactc gaacgtcatg tccgtatttt tcaccaaaca aagccattgc
    24841 acccatgttt ttggctgtat cgatatctgt ttcaattgtt tcaactggga tagcttccca
    24901 gattttttcg ttgacgattc tttccatttc agctaattca tctgaagtga tttgaccaaa
    24961 gtgggtaaag tcgaatcgta aatgtccagg agcgactaaa gaaccagctt gatttgcatg
    25021 ctcgccaagt acttctttca atgccttgtg cagtagatgg gttgctgtat ggtttttgat
    25081 gatccgattg cgcatcgatt gatcgatcaa tagatgatag gtttgtcctt cactcattgg
    25141 tgcttttact tctacggtgt gcataaattg accattaggc gctttttgaa catctgtaac
    25201 aactgctacg atttcgccta cttcattcat gatccatcct tgatccgcta cttgcccacc
    25261 catttctgca tagaaaggtg tttgatcaaa gatcatttga gcttcacctt ctgcgacttc
    25321 attcaaaaga gactcacctt taacgatgac caataattga ctatctgatt cttgttctgt
    25381 gtatccaatg aatttacttt ctactttgat atctgtcaat aaagcagatt gtacccccat
    25441 tgatttttca gtactgcggg cagagcgagc acgttcgcgt tgtgcatcca tttctttttc
    25501 aaaaccagca tgatcaactt tcagtccttc atcttctgcc acctcttccg ttaattctac
    25561 cgggaagcca tatgtgtcgt atagtttgaa gatgtctttt cctgctagag tcgtcccgtt
    25621 ttcgtttttt acttcttgga tcacttgatt taagatttcc aaaccttcat tgattgtttc
    25681 attgaaacgt tcttcttctg tacggataac tttttcaata aattcttttt gttgaagtac
    25741 ttcaggataa taacttacca tgatttcccc aacaacaggg actaaacgat ataagaatgc
    25801 ttgttcaata cctaattttt tcccatgcat gacagcacga cgaagcaaac ggcgtaagac
    25861 ataccctctc ccttcattcg atggcaatgc accgtcgcca atagcaaatg aaagggcgcg
    25921 aatatgatct gcgattactt tgtaagaaat atctgttact gggttttcac catattttac
    25981 ttgtttgctt agcttttcta cggcgtggat aataggcata aacaagtctg tctcaaagtt
    26041 cgttgacgca tcttgaacga ttgagaccat gcgttccaat cccatccccg tatcaatgtt
    26101 tttatgagga agtggttcaa atgtgttatc aggcttatgg ttgaattctg aaaatactaa
    26161 gttccagatt tctaaataac gttcattttc tcctcctgga tagttttcag gatcgtcttc
    26221 tgctaaatcg ttataagctt ctccacggtc atagaaaatt tccgtatccg gaccacatgg
    26281 gcctgcaccg atatcccaga agttgtcttc tacatcaata atgtgatcta gtggcaggcc
    26341 aacttcttca tgccagatgc gttttgcttc tgtatctttt ggataaactg ttacataaag
    26401 tttttctgga tcgaatgcca tccattttgg atcagtcaaa aattcccatg cccagtggat
    26461 ggcttcattt ttgaaatagt caccaatcga aaaattaccc agcatctcaa acatcgtatg
    26521 gtgccgtgct gttttaccga cattttcgat atcatttgtt cgaatagatt tttgggcatt
    26581 tgtgattctt ggattttctg gcacaactga accatcaaaa tattttttca atgttgcaac
    26641 accagagttg atccacaata aggttggatc gttcacgggg atcaaagacg cactaggttc
    26701 aatcgtatgt cctttagatt ggaagaaatc aagaaacatt tgtcgaactt gtgcactact
    26761 taattgtttc atgtcattac ctgctttcta taaattaaat acaaaaaaac accatcacag
    26821 ccaaggacga aaactcgcgg taccaccttg attgcaatga tgtgtaatca ttacctctta
    26881 aactcgataa cgctgagctg cgtcggtatt tctaccaaaa tagaaaaagg gagcaatttg
    26941 attagtgact attctttttt cagccaagaa agaattttct gtgagtctta aaaaacaaat
    27001 catatccttt tcgtacttaa ttagtatacg cattctattg atcactgtca atatctcaat
    27061 ttttattttc atttcctttt ggtcatactc cacgattttt ggtacgataa gaataaagga
    27121 atcaatacat ctctgctatt catgacaagg aggaatatga tgaaaaaaat agttggagcg
    27181 gatgaatgga tacgcgcagc tagctgcttt ttgagatatc aagtttttgt attagaacaa
    27241 gggattcctg cagaactaga attcgacgga aaagatatcc cgcaacaaac ctattatcta
    27301 tttcttgatc aaaaaagacc agtagctact ttgcgttatg aaaagaaaac acctacttgc
    27361 ttcaagccgg aacgattttg cgtagcaaaa gaataccgag gaaaagggtt aggcggtcag
    27421 ttgcttgaag ctgctgaaaa acgggcggtt tcagaaggtt gtcagactag ttatgtagta
    27481 gctgaaatga cggctgtaga tttttatgaa aaacaagggt atcatacttg cacagaacct
    27541 tttattgaag atgaagtact ttgtatcgga atgaaaaaaa gtctagctta aaaacaagag
    27601 attgtgacac gccttttgtc acaacctctt gttttttatt tatgtgaatt tttcttattt
    27661 ttacgagcag tacggctttg ctgtctgcgt tcgattttgc gttctttttt atttttttct
    27721 gcaattgccc aatcgatttt tttcttataa ccaggcttga tctttttctt tttcttcttc
    27781 acaagaccaa tcagcgtggg atctaataca tcttttgatt tttctcgttt ggcacgtcta
    27841 ttacgatcgt atgttttgac gatttccccg tttttgattt cttttggttc aaatgagacg
    27901 cccaattttt ctatcgcatc aatggcttgc tcatcatttg gcgaatataa cgtaatggcc
    27961 gttcctttta agccattacg tccagtacgt ccgacacgat ggataaagaa gtctagatct
    28021 tctggaattt ctgcattaat aacatgagag acaccttcga tatcgatccc tctagcagct
    28081 aaatcagtcg ctacaacata ttgatactcc agattctgta cttgtcgcat cactcgtttt
    28141 ctctctcttg gggtgatgtc tccatgaatc tttgctactt tcaagccttg gtttttcaag
    28201 taatcggcaa tttcatccac atgctgtttt gtattggcaa atacgattgc taaataagga
    28261 tgaccaattg tcagcagttg ataaatcatt tgattctcat ctttaccttt tgttgaaatc
    28321 agccaatttt caatgtcttc agaaataact gcttttggtt tgatttcttc aatgattgga
    28381 ttttccatgt attttcgtaa gaatggacga agtttttctg gaatagtggc agaaaaaact
    28441 aaaaactgca gcttttctgg taatcgactt gcaatttggt ctacttcatt taaaaaaccc
    28501 atatccaatg tcatatccgc ttcatcgaca acaaatgcaa atgcggtgtg aatcttcagc
    28561 gcttgttcat tcatcatgtc taatattcta ccaggcgtgc ctactacaac ctgtggctgt
    28621 tggtgatgca gacgatttaa ttgacgctgt ttgtctgtac cgccgacaaa attcgagaca
    28681 cggatctccg gtgtagaaaa tttagcgatt tgtgtagctg cttcatagat ctgtgcagct
    28741 agttccctac ttggagctgt aataacaact tgtacttcct ctttttctgc attgattttt
    28801 tcaaacaaag gcaacaaaaa cgtatgtgtt tttcctgtac cagtttgaga ttgcccaatg
    28861 atattttttc cttttgcaat taaaggaatc aaacgttcct ggacctctgt gggctgtttg
    28921 aagccctttg cggttaacgc ttcattgata aacggtttga agcggaatat atcaaaatta
    28981 ttcattcgtg cacctcttct ctttaaatta tcacgacttt ggcattataa cacagacaaa
    29041 gcgtttttgc tcagctaatt tcgagaatca tcatcctttg tttggccaat cgtgctaaca
    29101 gtatatgtgt gactagcttt ttcataaaac agaatccgtt tttttctcaa aaatgatagc
    29161 aagatattta aaataaaaat accttgtagt aacaagacac cgagagaaat gaatactgca
    29221 ctcatctgca acaccgtatt cgttgtcgaa ttcatgattt gctgaagcaa ctgccccaac
    29281 cagcttaaac cataaaaaag aaagtacaga tacccgtagc ggatcatcaa tgcttttaaa
    29341 gaaattcgtt cgcggtcttc ttccaccaaa cggatacgca caattttttt gccaagtgtc
    29401 catccattgg ttataaacgg tacaatcata aagtataccc ctacttctaa taaaagccac
    29461 cagatatgag aagtaactgc ccctgaatcg aacgcaattt taaagaaaat cgccgctacc
    29521 aaattaataa gagataaaaa tgtccagtcg atcaaataag cgaccaagcg tcgagtcaat
    29581 gagacagtct ttcctttttc ataagaaagt tcatccattc gtcttcttgt aggaagcata
    29641 aatgtaaata acggcgtaac gacaaaacca atgattccac ccaatgtatt tgtcactaaa
    29701 tcattcacat caaataagcg gtatggtctt gggtagataa aataaagtcc acttagctgc
    29761 gtcaattcaa aaaatagaga aaggcagaaa ctagcaatca tcgttttcat aaaagaaagc
    29821 cggaaataat atcttaaata aatgccaaac ggtatgagta ataaaacatt aaaagctggt
    29881 tccaaaaata cactctgctt cattgccggc aggtaggtac taggttcaga caagaccaat
    29941 accgtgttgt ctctgaaatg ttgccatgaa gcaaataaat gcagctccat ctttggccct
    30001 gtcatttggg caaccgtctc ctttgccgga agtggtaaga tcaccaaaaa atacgcacac
    30061 aataaataaa aaacgaaaga atacaaaata actgcccttg ttactagaaa tgttccatac
    30121 tttcgatatt cataaataaa aaaaacagat gagatcgcta aggctaaaaa tggaaaaaca
    30181 atcagcgcaa aacgaatcgg ttcgatataa cttgccatat gactcctcct tgattctttg
    30241 tatctctctt atcttagcag tcctttgctg tttcaagcaa gtaacgaggc tattatttct
    30301 catttctttc aaagtaaagt aagataaaca caaagggggt gtcgagatgc tgaatatgta
    30361 ctttgttttt ggcgtaccta tttttttact gttcctttat gctacgatcg cttatgtaag
    30421 aaaaagaact acaattcatt atttaggatt tattctcctg attatttcgg gtttcatgct
    30481 agtcttcaat cttcagactt ggcagcaagc acttcttgaa atggataaaa tgactccaca
    30541 tgctttgtct aaagtgcttg gctaccctgt ctatctgatt tggcttccca ttttcatttc
    30601 tggttgcttg gttttattaa atatttatcg cggcgtacgc cgaatagttc agttacgcaa
    30661 atcaaagtaa aagacagaaa tcggttgagc ccgatttctg tcttttactt tgctatttca
    30721 tcgtagacaa aacgacattt acgtgatcaa aattaacgag tacttttgac atttcttcca
    30781 cgtactcctc atttaaataa aatattttgt ttggcagaga agtgcagttc taataaaatt
    30841 cgaatgtttt agctatctac gttttaaata gagataaatc gggataccag caagtgtcaa
    30901 tactatcccc atcgaagcta aaaaggtctg agtgataagc gtgcttgata cgataaaagt
    30961 ccctccaatg attgctacta gtggaataaa cggatacatt ggaactttgt atggtcgaaa
    31021 caaatcaggt tcttttttac gaagaagaat gacaccaaca aagaccatcg tataaaaaat
    31081 ccaaatgaca aagatcagca tatccgttag tgtatcaaaa ccaccgatca tcatcatgcc
    31141 aatagcgatg actagctcta agatacctgc ggctacagga actttagttt tatcatgaag
    31201 tttagcaaag agcttgctaa aaggcaggtt gttttctttt gccataacat aagggagacg
    31261 cattccagta agggtatagc cattgatggt tccataaaca gaaatcaaga taccaactgt
    31321 gaccagtctt ccaccgaagc cgccaaaaat catttttgca acgtcacttg ccgcattgct
    31381 gtttcctgcg actccgtcga tagatgcggt tcttaagaac accgcattta ctaataaata
    31441 aacgatcatg attccgatga ttcctaaaga aattgctttt ggcaaatctt tcgccggctt
    31501 tttcaattct cccgaaatat ttcctacgtg tatccaaccg tcgtatgcga acatcgttgc
    31561 tagcaagccc gctcccaagg ctgagaaaaa tgaaagattt tctcctgctt ggatcggaaa
    31621 cagttggaag tctactcctt cttgtcggaa caaaccgaaa atgacgatca caaacaaagg
    31681 aataagcttg cagacaagcg taatcgactg aaaagcccct ccagctttag aacctaaaaa
    31741 attgatcaac aggatcgata cagcagctgt aacagctacg ggaacaatca ttgactggga
    31801 aagaccaaat agattgacga actgtgtacc gaaaatgatc gacaaggctg ctacatttgc
    31861 tggaaaataa atcacgactt gcgcccagcc caataaaaaa gctgctgtat ttccgtaaat
    31921 ccgttcgata tatttaatca tccctcctgt ttctggaata gcagctgcca gttcagctcc
    31981 tgttagtcct gcacagacag aaatcatacc accgagaaac caagaaaaca tatgcaaact
    32041 ggcggatcct gtaacttctg ctacgcttgc ggctttaaaa aatacccctg caccgatcac
    32101 tgtgcccata acagtcgata aagcagtaaa aaatcccatc gtacgtttta attcattttc
    32161 tatttttact tcttttactg gcgtggcttg atattcttcc atcccttgtc ccctttcata
    32221 ccatagccaa tcccaaaagt ataaaaaact ttttggatgt ggttcttgtt ttataccgtc
    32281 tctaccaatt tttctttcag tttttccaac atatcctttg tcatcacatc taagtcgtat
    32341 ttcggcgaaa agccccattc ctcttgcgca caagaaacat ctagtgaatt tggccaagat
    32401 tctgctattg actgacgtac aggatccaca tcataatcca tttcaaaatc tggtatgatt
    32461 ttttgaatag atgctttgat ctcttccggg tcaaaagaca tcgccgatat attgaaggca
    32521 tttcgatgaa ccaatcgatc aggatctgca ttcatgagtt ttataatggc atcgatcgca
    32581 tctggcatat acatcatatc cattgatgta ccttgatcaa tgaaactagt gtactttcct
    32641 tctttgattg ctgaataata aatatcgact gcgtagtctg tcgtaccgcc tcctggcaag
    32701 gttgcataag aaatcaatcc agggaaacgg acaccacgag tatctacgcc atatttcaca
    32761 taataataat cacatagtag ttctccagct accttcgtta ccccatacat ggttgtagga
    32821 cgctgaagag tatcttgtgg ggtatgatct tttggagtat ttggaccaaa cgcgccgatt
    32881 gaacttggcg taaaaaattt cagctggaat tctctagcga cttccaatgc attgaccagc
    32941 ccagtcacgt tcaaattcca ggctaattgt ggttttgctt ctgcaacagc tgacaaaaga
    33001 gcagccaaat gaatcaatgt gtccacttga tattgttctg ctatgctgcg cattttttcg
    33061 taatccatta catctaggat ctcaaagata tcgtttttct caatgacttc aggcatgcgt
    33121 atatctgtcg caatgacatt ttcactgcct agttcttgac gtagccgtgt gatcaactct
    33181 gaaccaattt gtcctaaaca tcctgtcacc aatacttttt tcatgatgat cctccctgat
    33241 cttttttact actatcttca gatgattaac aatatatgcg tgaacatgtt ctctaatttt
    33301 aaatagacga aaaaactaaa tttagttaaa taatttccat ttcttttcct attttttgat
    33361 aaactgctac tgcttcatca agcatttccc tcgtatgttc cgcagtcggc atatttctga
    33421 tcctgcctgt cccaagaggc acagttggat aaacgattgg tttagcataa atcccatgtt
    33481 cgatcagctt cttagagaaa gtctgagtca ctttttcgtc tcccaaaatg actggagtaa
    33541 taggtgtttc agacataccg atgttatagc ctactttttt caattcttct ttaaaataat
    33601 tagcattttc ccaaactttt tcgacaagtt ccggatgttc ttgcatcaaa gtaatcgaag
    33661 ccaatgcagc tgcagctgca cctggagtta gcgaagtaga aaataggaat ggccgacttc
    33721 tagctttcaa ccagtcgatt agtgttttcg atccagctac ataaccccca acaacaccta
    33781 tagctttcga taacgtgccc atttgcatat cgattttgtc gcttaatcca aaatgcttga
    33841 cggttcctgc accttttcca gttacgcctg agccgtgcgc atcatcgacg taggtgatca
    33901 gtccatattt ttcaacaatc ggaataattt ccggcaatcg tgcaatgtct ccatccatgg
    33961 agaaaacacc atctgtgata tacatgattt ttttatattt cttactttct atcgcttcct
    34021 ttgctttttt ctcaaggtct ttcatatctt gatgtttaat tcggatgatt tttgctccgg
    34081 ataagcggca accgtcaata atagatgcat ggtttaattc atccgataag atagcatctt
    34141 cttttgtcat tactgcagag atagcgccca tattgcagtt gaatccagat tgaaaggcga
    34201 ttgctgcttc tgtccctttg aattctgcga ttttttcttc taattgctga tggattttca
    34261 gcgaaccatt gatcgttcgg actgctcctg ctcctacacc ataagtttcg gttgcttcaa
    34321 tacatgcttt tttcaattct tcgcgattgg caaatccaag ataattgttg gatgctagat
    34381 tgatcatctt ttttccgtct acgatgatac aagcaccatt ttcactttct agtatgtcga
    34441 tcgtattgta taaccccttt tctttcagtt gatccaattc tttctctaaa tacattgtta
    34501 gttctttgga agacattgtc tccacctcca tattcatctg tcttgcagaa cataccaaac
    34561 atatatcgtg tcattcatct acaaagcaag tatgctatat ttttgataac gcttacactg
    34621 attatgagaa ttatttaacc acatttttta tttacagtat ctttttactt tcaaatgact
    34681 tatatagtat gaacaattac cttttagata atgatctatt ttactctacc tgggcagata
    34741 aatacaacac aaccattgat agaagccctt tcgttaaaat caattgtatt ctgaatattt
    34801 aatttattta ttgcatagac caataaaaat acataaaatt tccatcttcg tttatcagca
    34861 atttttaatt ttactctctg aatatttctt aaaagtttta cttgttgaat tcgaaaaaag
    34921 gactgtgaca aaagtcttgt cacagtccta ttcttccgaa ta
//
LOCUS       DADLIO010000023        34687 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.023, whole genome shotgun sequence.
ACCESSION   DADLIO010000023 DADLIO010000000
VERSION     DADLIO010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34687
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.023"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            591..1280
                     /locus_tag="JOX41_001278"
     CDS             591..1280
                     /locus_tag="JOX41_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAY6449034.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1267..2475
                     /locus_tag="JOX41_001279"
     CDS             1267..2475
                     /locus_tag="JOX41_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAY6449035.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2769..4040
                     /gene="serS"
                     /locus_tag="JOX41_001280"
     CDS             2769..4040
                     /gene="serS"
                     /locus_tag="JOX41_001280"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HAY6449036.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="JOX41_001281"
     CDS             complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="JOX41_001281"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HAY6449037.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6578..7273)
                     /locus_tag="JOX41_001282"
     CDS             complement(6578..7273)
                     /locus_tag="JOX41_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HAY6449038.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="JOX41_001283"
     CDS             complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="JOX41_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HAY6449039.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8472..8663)
                     /locus_tag="JOX41_001284"
     CDS             complement(8472..8663)
                     /locus_tag="JOX41_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HAY6449040.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8684..9574)
                     /locus_tag="JOX41_001285"
     CDS             complement(8684..9574)
                     /locus_tag="JOX41_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HAY6449041.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9561..10328)
                     /locus_tag="JOX41_001286"
     CDS             complement(9561..10328)
                     /locus_tag="JOX41_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAY6449042.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="JOX41_001287"
     CDS             complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="JOX41_001287"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HAY6449043.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="JOX41_001288"
     CDS             complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="JOX41_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HAY6449044.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="JOX41_001289"
     CDS             complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="JOX41_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HAY6449045.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14944..15282
                     /locus_tag="JOX41_001290"
     CDS             14944..15282
                     /locus_tag="JOX41_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449046.1"
                     /translation="MSPFRSAALEEESDPRINDVVLSTGNINQKYIVRDIVFVVECLE
                     ADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQKKRDGKYFLELFAYGT
                     VIQFIQTTIG"
     gene            complement(15450..16208)
                     /locus_tag="JOX41_001291"
     CDS             complement(15450..16208)
                     /locus_tag="JOX41_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HAY6449047.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16226..17044)
                     /locus_tag="JOX41_001292"
     CDS             complement(16226..17044)
                     /locus_tag="JOX41_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HAY6449048.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="JOX41_001293"
     CDS             complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="JOX41_001293"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HAY6449049.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="JOX41_001294"
     CDS             complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="JOX41_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HAY6449050.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18172..19506
                     /gene="dnaA"
                     /locus_tag="JOX41_001295"
     CDS             18172..19506
                     /gene="dnaA"
                     /locus_tag="JOX41_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HAY6449051.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19704..20834
                     /gene="dnaN"
                     /locus_tag="JOX41_001296"
     CDS             19704..20834
                     /gene="dnaN"
                     /locus_tag="JOX41_001296"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HAY6449052.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21063..21305
                     /gene="yaaA"
                     /locus_tag="JOX41_001297"
     CDS             21063..21305
                     /gene="yaaA"
                     /locus_tag="JOX41_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HAY6449053.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21292..22416
                     /gene="recF"
                     /locus_tag="JOX41_001298"
     CDS             21292..22416
                     /gene="recF"
                     /locus_tag="JOX41_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HAY6449054.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22413..24359
                     /gene="gyrB"
                     /locus_tag="JOX41_001299"
     CDS             22413..24359
                     /gene="gyrB"
                     /locus_tag="JOX41_001299"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HAY6449055.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24379..26850
                     /gene="gyrA"
                     /locus_tag="JOX41_001300"
     CDS             24379..26850
                     /gene="gyrA"
                     /locus_tag="JOX41_001300"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HAY6449056.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDIAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27086..27385
                     /locus_tag="JOX41_001301"
     CDS             27086..27385
                     /locus_tag="JOX41_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HAY6449057.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27435..27947
                     /gene="ssb"
                     /locus_tag="JOX41_001302"
     CDS             27435..27947
                     /gene="ssb"
                     /locus_tag="JOX41_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAY6449058.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27973..28209
                     /gene="rpsR"
                     /locus_tag="JOX41_001303"
     CDS             27973..28209
                     /gene="rpsR"
                     /locus_tag="JOX41_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HAY6449059.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28352..30325
                     /locus_tag="JOX41_001304"
     CDS             28352..30325
                     /locus_tag="JOX41_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HAY6449060.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30331..30783
                     /gene="rplI"
                     /locus_tag="JOX41_001305"
     CDS             30331..30783
                     /gene="rplI"
                     /locus_tag="JOX41_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HAY6449061.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31057..32424
                     /gene="dnaB"
                     /locus_tag="JOX41_001306"
     CDS             31057..32424
                     /gene="dnaB"
                     /locus_tag="JOX41_001306"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HAY6449062.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33204..34496
                     /locus_tag="JOX41_001307"
     CDS             33204..34496
                     /locus_tag="JOX41_001307"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HAY6449063.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT        10569 a         6743 c         6858 g        10517 t
ORIGIN      
        1 ggagtgtttc ccgattcgtt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagtaattgt caactctttt ttaaaagttt tttcgatttc gtttttcgaa atcttccagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcat
      241 ttccaacatg tcaacaactt attttttatt atttaataag ttattggtgt tcttttgaac
      301 aaataataat atatcaacat cacatgtgaa agtcaataag aaaatgctta tttatcaaca
      361 tttctagctt acatgatcat tggttagttc tggtcctttt tcgttcgtct ttataactcc
      421 gagagacgta aaatcctttt gttttcagtt taatgttcat gttcttgtct tattcacacc
      481 aactagatgt ctcaccttct aaaattttcc ttaacaaagt gctgctttta tctatttctg
      541 cttttttttg ctagaataat agtaacaata tgactctgga ggatttattt atgaaaattt
      601 tgattgctga cgatgataaa gaaatcgttg aattattaag tatctatgtt cacaatgagg
      661 ggtatgaagc agtaaaggct tatgatggga aagaagcatt atctaaaatc agaacaatcc
      721 ctgatattga attacttatt ttagatatca tgatgcctga gatggatggg atgcaagtag
      781 tgaaagagct acgaaaagaa tcccaaatac caatcattat gctgacagca aaaactactg
      841 atatggataa gatcaaagga ctggtcgctg gtgcagatga ttatgtgacc aagccattta
      901 atccgttaga agtaatggct agagtaaagt ctttattacg gcgtacaaaa atgcagattg
      961 ccccagatca gcctgatgta ttagaagtaa atgcattaat catcaataaa gactctcatg
     1021 aagttaaaac aatcgatggg aaagaaatcc agttaacagc tttggaattc ggtatcctct
     1081 acttgcttgc tagtcatcct aatcgagtat ttagcgcgga tgaaattttt gagcgtgttt
     1141 ggaaacaaga aagtattgtc tctgctaaaa ctgtcatggt tcacgttagt catttaagag
     1201 ataagattga agaagcaact ggtggtgaaa aagtcattca aaccgtttgg ggagtgggct
     1261 ataaaattga cgcaagatag taaacgagca actgaaaaac gccgtcggat caatttgact
     1321 tcaaaagaaa tcagcgaatt gttagcggaa ggaatcatca cgattatcct tttgcttcta
     1381 ttaaatgttt ctattctggt tgttatcagt tcggtgatca acagttcacc ttctttgacg
     1441 aatgcgattt gggattcaaa gaatattttt gcagaacgat tgaacactga tttgttctgg
     1501 aacggccgga attttattat tccctttttc tttctattag atattggtgt tttgtattgg
     1561 cgcttgattc gaagatatcg ccaaatgcaa ttgcggcata tcatcagcga acttcactac
     1621 atcgcaaacg gaaattatga tcatcgtatc ccttttgaac tgagtggtga cttaagccga
     1681 gtggtaacaa gtatcaatgg attggtggat agtaccgtag cagcgattga agacgaacgt
     1741 aaaatcgaaa aatcaaaaga tgaattgatc acgaatgtca gtcatgatat ccgtacccca
     1801 ctcacgtcca tcattggata cctaggactg atagaagatg gccagtatca ctcagaagaa
     1861 gatcttttaa agtatacgca tactgcttat atcaaagcaa agcagatgaa atctttagtg
     1921 gacgacttat ttgaatacac taaggtacgc cagcctgctg tcccggtgaa tttttctgcc
     1981 tttgacatga tccagttgat cgaacagtta gcagctgatt ttgagttgga agcttctaaa
     2041 aaaaatatcc aaatacttgt tcaatcaaaa gtagactccc ttatcatgga tggcgatacc
     2101 gaaaaacttg tacgtgtctt caataatctt ttgacgaatg cgttgaaata cggaaaagga
     2161 gcaacgaaga tcgtaatcga agtagaacgt atcggttcag aagttgttgc aacagtcaaa
     2221 aataacggag caatgatccc acaacaggca atcgataatc tattcgaccg tttttatcgt
     2281 gtagaagaat ctcgttcaca agcaactgga ggaactggac ttggtttagc aatcgctcaa
     2341 agcattgtgg ctttgcacgg cggatacatt tatgcaaaat cagataagca atggacttct
     2401 ttcatcatgc accttccaat caagaaaaat gaaaaattac ctattgatac acaggaagtt
     2461 attgacgaaa gctgaaatat tcgctattct tattacaatt attagaataa atgaaaaaca
     2521 cagaacccag tacactttat tctttttcag agagctgatg gcaggtgtaa atcagcaaag
     2581 gataatttgg aagttccagt tcgtttacgt gccctttcga aataagaaag gtcggttcaa
     2641 cagccgttat gtgttcaaca agtgcagctg acgctgaact tgggtggtac cgcgaatttc
     2701 agactgattc gtcccaagaa taatgggatg gatcagtctt tttttatttt caaaaaggag
     2761 gaaatcatat gttagatgta aaaatgatgc gacaaaatat tgaagaagta caagaaaaat
     2821 tgatgactcg gggcgtaaaa aaagaaacat tagctgaatt catggaacta gatgaaaatc
     2881 gtcgtaagct actagtcaaa agtgaagaat taaaaaaata tcgaaatgat gtttctgctg
     2941 agatcgccca attgaagcgt gcaaaagaag atgcttctgc taaaatcgct gaaatgaaag
     3001 aagtcggtgg caacatcaaa gcattggata ctgaaattgc tgaagtggat gaaaaattga
     3061 aacaaattgc aactactttg ccaaaccttc cccatgattc tgtgccagtt ggaacagatg
     3121 aagaggacaa tgtagaaatc cgtcgttgga gcgaaccacg tacatttgct tttgaaccaa
     3181 aaccacactg ggaaattgca gaaaatcttg atattttaga ttttgaacgt ggcgcaaaag
     3241 tagccggtag ccgttttgtc tattacaaag gattaggtgc tcgattagaa cgtgctgtct
     3301 acaacttcat gcttgatcag catatttacg aacacggcta tactgaaatg atcactcctt
     3361 atatcgtcaa cagtaaagcg atgtttggta cgggacaatt tccaaaattc aaagaagatg
     3421 ttttccaatt ggagaatact gatctaacat taatcccaac agctgaagta ccattaacta
     3481 actattataa tgatgaaatt ttagatggtg cagatttacc tatttatttc actgcactaa
     3541 gccctgcttt tcgttctgaa gccggaagtg ctggtcggga tacacgagga ctgattcgtc
     3601 ttcaccaatt caataaagta gaaatggtca aattttcgga tgtagagcat tcttacgaag
     3661 aattggaaaa aatgacagct gatgcagaag atatcttgaa aaaattgcat ttgccttatc
     3721 gtgtgatggc cttatcaact ggagacatgg gcttttctgc agctaaaact tatgacttag
     3781 aagtatggat acctgcacaa gatacttatc gtgaaatcag ttcttgttct aactgtgaag
     3841 atttccaagc acgccgcgca atgatccgtt atcgcgataa tgatggaaaa atccactata
     3901 ctcatactct gaatggttca ggacttgcag ttggccgtac agtagctgcc attttggaaa
     3961 actaccaaaa tgaagatggt tctgtcacag ttccagaagc gctcgttcct tatatgggga
     4021 atctgaaagt tattaaataa agaggctgtg aaaaagccgc ttagtttcga gtattaagaa
     4081 aaattttgtg aaaatggctt tccacatttt tgcataaatt ggacttaata ccgagaaact
     4141 ggcttttgaa caccatttat cgagaggttg tgaaatcagc gaattaacct gagtattaga
     4201 gaaaaaaatg gaaaaatagt ccctcatatt ttaccgtttg ttgaactaat accgagggtc
     4261 agctgattga acaccgttta gtggagaggt cgtaagccta ccccccagct cctagttaca
     4321 aggacaaatt caaaaaacag ctcttcatat tttatgaatg ttgtacttgt gattcggagg
     4381 tggcaaggga acactgttta ttcaaaaaga ggctgggaca gaagcgttta actccaagaa
     4441 ataagaagaa attcacgaaa attgcttttc aaatttttgt gaatttcttc ttatttccga
     4501 aggagttgct tctacttccg ccgtttatac gtgtttagag cgtgagacaa aagtgttctt
     4561 tacttttgtc ccacgctctt taatgttttt aagattcaac tgaatagttt ggtgcttctt
     4621 ttgtgatttg tacatcatga gggtgtgatt cttttaatcc actgccgctc atttggataa
     4681 attgcgcttc atcacgtaat tgctgtagat tggctgcccc aacataaccc attcctgaac
     4741 gcaaaccgcc gatcatttgg aaaataatat ctgcaacact tcctttataa gcaacccgac
     4801 cttcgattcc ttctggtact aatttatttg cttcattgac actaccttgg aagtaacggt
     4861 cttttgaacc tttttccatc gcgcctaatg agcccatacc tcggtatgtt ttgaatcgac
     4921 gtccttggaa gatttcgaat tcacctggtg attcatctgt ccctgccaac atacttccta
     4981 gcatcactgc atgtccgccg gcagctaatg ctttgacgat gtcaccagaa tatttgatcc
     5041 ctccgtctgc aataatcgct ttgccatatt gacgagcaac tgatgctgca tcataaatag
     5101 ctgtgagctg aggtacacct acaccggcta ccacacgtgt cgtacaaatc gatcctggtc
     5161 cgataccaac ttttacgaca tctacacctg catcatataa agcttttgtc gcttcagccg
     5221 tcgcaacgtt tcctgcaatc aatgttgcat ctgcaaaagt tgaacggatt tcttgaattt
     5281 ttcggatcac acctgcacta tgtccatgag ctgtatcgat gatgattgca tctgcccctg
     5341 cttctaataa agcattcgca cgctcaaatg tatcgcttgt tacaccaacg gctgctgcta
     5401 caagcaatcg accatgttca tcttttgctg catttggaaa ttcgatcact ttctcgatgt
     5461 ctttgatcgt gatcaatccg cttaaacgac cttcgttatc tacgattggt aatttttcga
     5521 ttttatgttt ttgcaaaatc ttttctgcat cttttagaga ggtacctact ggggcagtca
     5581 ctaagttgtc ttttgtcatc acatcagcaa tcggcatgtg ataatctgtt acaaaacgca
     5641 tgtcgcggtt tgtaattatc cctaccaatt ttctgttttc aagtgtttca acgattggca
     5701 caccactgat acgatatttg ctcatcaatt cttctgcgtc tgctacaaga tgctgtggcg
     5761 ttaagaagaa cggatcaatg attacgccac tttcagaacg tttgactttt cttacttcat
     5821 ccgcttgctg gctgatcgtc atgtttttat ggatcacacc tagtccgcct tgtcttgcca
     5881 tagcaatggc catcttgctg tcggtaacag tatccatact tgcactgatg attggaatat
     5941 tcaacttaat atttttagct aattgtacgc tcatatccac ttcgtttggt aacacgtgac
     6001 tttctgctgg tatcaataag acatcatcaa aagtaaatcc ttttttcgtg aactttgttt
     6061 cccagttgga catttttagt accactcctc taatttagtt tatctattaa aataattgat
     6121 tttttcattt aagtcaatga tctacttgga atcaagttag ctttctcata gaataccaat
     6181 ataaagcgtt tacatctgtg tgtattaaaa gagattgtaa aaaagctgtc ctgcatcaag
     6241 taataagaac agccaatcaa aaacagcttc tcatgttttt gaattggttg ggtttattac
     6301 cgcagatgca aacttttgaa caccgtttag tggagaggct gtgaaaaagc tgcttagttt
     6361 cgagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa attggactta
     6421 ataccgagaa actggctttt gaacaccgtt tatcgtaaaa agggactgtg acaagacttt
     6481 tgtcacagtc ccttactatt atttaactat ggataaacaa aatgaggttc tttactaccc
     6541 ctagatatct agcaaaatag ctgatctttt tgctagttta tcttcttggg acggataaac
     6601 ttccaataat cccgtatttt ttcttcaagt agtaacggat tgctaaagca gttgccccga
     6661 taatgataac tactactgga tctaatactg gattgataac tggtggcaat agtgttgtcg
     6721 cagaaaacag tacgacccaa agaagtgtcg ttccacctag gataagcaat gtcttaccca
     6781 ttcctggttt cttgcttcga tctgctccgg gatattcata ttgatagatg tatttgtaca
     6841 tcatataaaa gacccagcca ccgattgcag aacctagaac gagtgtagaa aagccataag
     6901 ctggcgttgt tccacgtgaa aacaatccgg taatcgcaat catgatactt aatagaccaa
     6961 gcaacagcaa cgtattatct aaccacatca ataaaggggt ggatgaattt tttacttctg
     7021 ctggcttatt gatgattgct tccgttcttt cagagactgt cccaaacaat tgacgggctg
     7081 ttcttccgcc tttttgttct gcaactaaag taggcagaat gtcatgaagg gcttttactt
     7141 tttcttcttc agacaaattc gctgcttcta aagatttttt caaatcaaaa atgtactgtt
     7201 gatttctttt ggttaatttt gtttctaaac tattgttttc ttttacgatt gctcgtaatt
     7261 gttctggttc cattatctaa tagtcctcct tagccgttcc ttttctcaac ggtcgtcaca
     7321 aaagacattc taccatattc tacagctagt ttgatagccc ttttacacat taaagcggaa
     7381 taacattacg tcgccgtctt gtacgacata atcttttcct tctaatcgaa cacgtccagc
     7441 ttcttttgct gcatgcatgt ttccgtaatg atccaagtct tcaaaagaga cagtttctgc
     7501 acggataaat ccgcgttcga aatctgaatg gatgattcct gctgcttgtg gtgctttgat
     7561 tccttttttg aatgtccaag cacgtacttc ttgttcccca gcagtaaagt aagtagctaa
     7621 gcctaacaaa tcataagcag cacggatcaa ctgatccaaa cctgattctt cgattcctaa
     7681 agcttctaaa aattccgctt tgtcttcttc atctaattct gcgatttctt cttctgcacg
     7741 agcactgacc acgatcactt ctgcattttc ttctgcagca aagttgcgca cttcttgtac
     7801 ataatgattc gcgtctgcat ctgctacgtc atcttctgag acattggcta cataaagaat
     7861 tggttttgtc gtcaataaaa atagtgattt aacgattttt tgttcttctt cagtaaattc
     7921 gatcgttcgg gcagattttc cttcttccag tacaggtttg attttatcca gtacagctag
     7981 ttctgccact gcatctttat ctttggtttt agcaactttt gctacacgag tatagcgttt
     8041 gttgatagat tctaagtctg ctaacactag ttccaagttg atcgtatcaa tatcttctag
     8101 tggatcaaca cgtccttcta cgtgagtaat attatcatca tcaaaacagc gaacaacgtg
     8161 acaaatagcg tctacttggc ggatatggct taagaattga tttcccaaac cttctccttt
     8221 acttgcgcct tttacgattc cagcaatatc tgtaaattca aaagtcgtcg gaacagtttt
     8281 tttcggatgt acaagttctg ttaagcgttg caaacgccag tcaggtactt ctaccatccc
     8341 tacgttgggg tcgatcgtcg caaagggata gtttgctgct tctgctcctg cttttgtgat
     8401 cgcattaaac aaagttgatt ttcctacgtt gggcaaccca acaattccag cagtcaatgc
     8461 cataaattta ttcactcttt ctctgcattt ttttcaatta ctttttttaa tttcttttca
     8521 aaatctcgac gggtcatcat gacgatatgt ccgcaattca tacatctgat tttgatatct
     8581 gcgcccattc gaatgacttc ccagcgattc gtctggcaag cgtgaggttt tttcatttca
     8641 acgatatcgt gcaagtcgta cataaaaata gcctcctttt tgtttattct tcatcaaatt
     8701 gaatattcaa gatatcaaga attcgagtca aatctttttg agaaagatat tcaatctcga
     8761 tcttaccttt cccatttttt tcttggatag ctacacttgt accaaattta tccatcaaac
     8821 gatcttcgct ttctcggata taatatggtt tttcctttgc tagccttggg atttttttct
     8881 tttcttttcc atcattttga tttaactcag aaacaagctg ttccagttgg cggacagtta
     8941 aattttcagt tactgcacga ttggctaatt tcaagatcaa tgttttattt tttaaaccta
     9001 acagcgtacg ggcttgtccc atagataaac gctgatcttg taccatttcc ttgacaagat
     9061 ccggtaaaga aagcaagcgc aaataattgg cgatataagg tctgctcttt cctaaacgac
     9121 tagctacttc tgcttgtgtt agtttcaggt ttttcatcag catctcatat gcttctgctt
     9181 cttctaacgg attcagatct tctcgctgca agttttccag cactgctact tgcatcatcg
     9241 cttcttcgtc aaagtctcta acgatagcag ggatcgtttc tttttcagct agtttggacg
     9301 ctcgaaaacg tcgctcccct gcaataatct catatccttt tactgcggaa cggcgtacga
     9361 tgatgggttg aaagacacct gattgttcaa tagaattagc tagttcctgc aaagatactt
     9421 cttcaaatgt tttacggggc tgatacggat ttggtcgcag ctcattcaat ggtagctgga
     9481 caacggtatc atcttttaca tccaccgtct ctaagttttc taaatcttga aacagtgcat
     9541 cgattcctcg gcctaatcct ttacttttct tcacgactta ccacttcctt tgccaatgct
     9601 tggtagactt cagctcctcg agaacgtgga tcgtagtcga tgatcggttt tccatgacta
     9661 ggtgcttctg ataaacgaat atttcttgga atgatcgttt cgtaaacttt ttcgcggaag
     9721 tatttacgta cttcttctac gacttcattt cccagatttg ttcgtgcatc atacattgtc
     9781 agtaagactc cctcgatctc taattctgga ttaaagtgtt tttggactaa acgaaccgta
     9841 ttcagtaatt ggcttaatcc ttccaatgcg taatactcac actgaacagg tatcaaaatc
     9901 gaatcacttg ctgtaaatga attgattgtc agatggccaa gagaaggcgg gcaatcgatc
     9961 aaaatataat catactgact gcttacttct gctaaagatc cttttaatct tgattctctt
    10021 gccatcattg acgtcaattc gatctctgct cctgctaatt ggagagtcgc aggcacaata
    10081 ctcaaatttt cgtgttcagt gatcaaagtt gcctcatcaa ttggcaattc attgactaga
    10141 acatcataga tgtctcttgt cacatcaggt tttctgatcc cgacaccact ggtagcattt
    10201 ccttgtgcat ccatatccac tagcaatact tttttgccaa ggctagcaag acaagcacct
    10261 agattcaccg tcgtcgttgt tttgccgacg ccaccttttt ggttcgcaac agatattatt
    10321 tgtgccatct cttctcctcc tatttgattg gctgcttatt aggcagtccg ggctttcttg
    10381 ggtatttctt tggggttggt ttcttttttt gaataacgat gatatgccgt tgatcagaga
    10441 cattcggcaa ggtaaccgcc tcttctttga ggaatttacc acctaataaa gcaatcgctt
    10501 gttttgcttc tgtcaattcc tcttcacttt ttgctgcttt caatgcataa aaatagcctt
    10561 cttgtttagc caagggcaaa cacaattccg ctaacacatt caaacgagca accgcacgag
    10621 cagtgacaag gtcaaatgat gcacgaaagt gaggattttg cccaaatgtt tctgcccggt
    10681 catgatataa ggaagcatcg attcctaata atcgggttaa ctcagataag aaggttattc
    10741 gtttattcag agaatcaacg atcgttatct gcagttctgg aaaggcaatt tttaaaggta
    10801 tgctaggaaa ccctgccccc gaaccaacat cgcataaaga taaaggttgc gtaaagtcta
    10861 cttcaaatgc taatgtaagt gaatcgtaaa aatgcttcag atatacgtct ttttcatccg
    10921 taatagctgt aaggttcatc ttttcgttcc attcgactaa tgtccgataa taaatagcga
    10981 attgattcat ttgatgatcg gtaagctcta tccctttttc tgccaaggat tggcgaaatt
    11041 cttctggtat cataaatatt cctttcattg tgaaacagca attgtttcac agattctctc
    11101 cctactttaa cgcaaaatct ctagacatgc aatccttcca tatggattct taaaaatttg
    11161 aaaagtaaga aaagccgata gactttttct ttctagtatg actcataaaa tatacacaga
    11221 agagagaact agctttgagc aatttctgca aaaactagtt ctctcttcta tttattatta
    11281 cgtattacgc tggttcactg actttcgcaa tcttcccttg ttcgatatag accattagga
    11341 tacttaggtc tgcagggttt acgccactga ttcggctagc ttgggcaatt gtttctggtt
    11401 ggattttctg caatttttgt tttgcttctg ttgctaatcc gttgattgct gcgtagtcga
    11461 tgttttctgg aatctttttc gcttccatgc gttttaattt ttctactttt tccatggctt
    11521 ttttgatgta gccttcatat ttgatttgga tttctacttg ttcgatttct tttcgtgtca
    11581 attcttcatt ttctggaata aaccgtagaa gttctgcata agtaatctca ggacgtctta
    11641 aaaagtcgct tgctagtaca ccatctttta atggtgccgc attaatcgtt gctaaaaagt
    11701 cttggacttc ttctgttggt ttgattcgta cattcatcaa acgtttgatt tcttgttcaa
    11761 ctgcttcttt tttcttcaaa taattcttgt attgatcttc ttttactaag cctacacggt
    11821 gacccatttc tgttaatcgc aaatctgcat tatcatgacg taaaagcaga cggtattcag
    11881 cacgtgaagt cagcaaacga taaggttcgt tcgttccttt tgttaccaaa tcatcgatca
    11941 tgacaccgat gtaaccgtca cttcgtttga tcactaaagg ttcttttccc tgaactttca
    12001 aagctgcatt gataccggca atcagccctt gtccagccgc ttcttcataa ccgcttgtac
    12061 catttgtttg tccagctgta taaagatttt caacgacttt agtttctaat gtcggacgga
    12121 gctggtgtgg ctctactacg tcatattcga tagcatatcc tgtacgcatc atttctactt
    12181 tttctaatcc agcaatagaa tgaagcatgt tgacttgaac atcctctggt aaagaagtag
    12241 ataaaccttg aacatagact tcttccgtat ttaagccttc tggttccaaa aataattgat
    12301 gacgtggttt gtctgcaaaa cgcacgatct tatcttcgat ggatggacaa tagcgagcgc
    12361 ctaccccttc aacgatccct gtaaacattg gggcacgatg taagttgtct cgaataattt
    12421 ggtgagtcgt ctcacctgta taggtcagcc agcaagattc ctgatctagt ttataggcac
    12481 tatctggtgt gctgaagcta aaatgattcg gctctttgtc accaggctgc tcttctgtaa
    12541 cagaatagtc gatcgtactt gattttactc gaggcggtgt tcctgttttg aaccgttcga
    12601 tagcaaagcc aagttctttt agatgattcg ctagtccaat agaaggttga gagttattcg
    12661 gacctgatga atatttcaat tcaccgataa tgatttctcc gcgaagtgct gttccggctg
    12721 taataacaac tgctttggcc cggtagctcg ctcctgtgga cgtcactact ccatgacaaa
    12781 caccatcttc gacgatcagt tcttcgacga ttccttgtct tagcgtcaaa tttggttctt
    12841 tttcgatcgt atgtttcatt tctgttgaat aagcatgttt gtctgcttgt gctcgcaatg
    12901 ctcggacagc tgggcctttt cctgtgttca acatacgcat ttggatatag gttttatcga
    12961 tattcttacc catttctccg cctaacgcat cgatttctcg aacgacaacg cctttagctg
    13021 gtccgcctac agaaggatta catggcatga atgctaccat gtccaaattt attgtcagta
    13081 ataatgtttt tgatcccata cgtgcagcag caagtgcagc ttctgaaccg gcgtgtcctg
    13141 cgccaacaac gatcacgtca tacgcatctg cttcataatg ttccaatcgt ttgttcctcc
    13201 ttttattttc ctaaacaaaa ttgactgaat aattgagtga ttagctcatc ttgtacactg
    13261 tcgccgacaa cttctcctag atagtcccag caacgcgtca tatctatttg aacgagatcc
    13321 acaggcattc ctgaatcaat acctgcaatg acttcttcaa gtgagaggga agctttttct
    13381 aacaacgcga tatggcgggt attagaaaca taagtagcgt ctctttctcc tgtttctccg
    13441 ctgaagaata aatcagaaat agctgattcc aaacgatcta gtccgtcgtt tttagctacg
    13501 gaaattgaaa aaactggttc attttcgatc aatttcttca atttttcttg ttccagctgt
    13561 gctggcaaat ctgttttatt tagaagaatg atccgtttca atccacttgt cgcttccaat
    13621 aattgttcat cttctgctgt cagtggttcg ctttggttta gaacaagtaa gatcaagtct
    13681 gcttctgcta atgcttttcg gcttctttcg accccgatcc gttccaccac atcttctgtt
    13741 tcccgaattc cagctgtatc gattagcttg agcggtaccc cccgaacatt gacatactct
    13801 tcgattacat ctcgagtcgt tcctgcaata tccgtaacga ttgctttttc ttctcttaac
    13861 aaatggttta acaaacttga tttgccgaca tttggccggc cgatgattgc cgtacttaac
    13921 ccttcccgca gaaccttccc ttgcttggat gtagcaagta gcgcttggat tctttgttgg
    13981 atcatctgcg ctttttcaag caataacttc gtagtcaatt cttcgacatc atcatattct
    14041 ggataatcaa tatttacttc tacttgtgct aatgtctcta aaatctcttg tctcaatgag
    14101 cggatcaaag cagacagatt gccgtctaac tgattaagag ctagtcccat tgctttgtct
    14161 gtttttgccc gaatcaaatc catcacagct tctgcctgtg aaaggtcaac acgaccattc
    14221 aagaatgctc gttttgtgaa ttcgcctggc tcagctaatc ttgcaccttc tcttaacaat
    14281 agctgcaaaa tttgattgac tacaacgatc ccaccgtgac aattgatttc tactacatct
    14341 tcccgcgtaa atgtctttgg tgctctcatc acggagacca tgacttcatc gacaagctga
    14401 ttgctcttgg gatcaacgat atgtccataa tggatcgtat gacttggtac ttctgataat
    14461 cgtttgtttc cagattgata aactttatct gctagttgca cagcttgatc gccacttaaa
    14521 cgaacgatac tgattgcacc ttctccaggt ggggtagaaa ttgccgcaat cgtatcaaat
    14581 tctaaagtaa tttcagccat tttttcactt cctttttcat tttgcgcaca aaaaaagtgc
    14641 ccactccacc ctttatgcac aataaacggt gaacttcgca ctttgactgc ttgttcttga
    14701 ttaaattctg gtcatagatt atcacacttg ctataaggaa tcaagtgttt aaaacaatta
    14761 gatgaagttg agcctgttct gcttccatta ccttatattt aattgtcctt ggatgtctct
    14821 ttgcgttctt tggtttattc gaagagaaga tactgtataa acaaggcttt atctttctta
    14881 aaaaaaacgg tacactaaat ggtagcgcta tctaaactat acacttttga aaggagaaaa
    14941 tatgtgagcc cgttcagatc tgctgcattg gaagaagaaa gtgaccctcg gatcaacgat
    15001 gtcgttttat ctacagggaa tatcaaccag aaatatatcg tccgcgatat cgtttttgtt
    15061 gtggaatgct tagaagctga tttgtttgac ccatcttttc ccaaagatga ccttttctta
    15121 acaacgaaga ggaaattaaa gacgaaggta cttgaatatg gtgcgaatgc agtaatcaac
    15181 tgtcattttg agtatcagca aaaaaaacgc gacggaaagt attttctgga actttttgct
    15241 tatggaacag tgatccaatt tatccaaaca acgattggtt aaatgaaaca gacaaaaaaa
    15301 gcggatcaaa actgaagaca gtttcgatcc gcttttttct atcaaagtta gtgactactt
    15361 catcgtatac tctgataaga atgatttcta gtaaaatata cttggtttga aaaactttgt
    15421 caacgtgatt tattcaaaaa gtaatggaat caataatatt ttttagcagg ttctactact
    15481 aaataacgat aaggttcctc accttccgaa tgtgttttta catgttcatc tttgcttaat
    15541 gcagcatgga tttgtttacg ttcaaatgca ggcattggtt ctaagaaaac aggctgccct
    15601 gtccgtttta ctttttcagc cgtgcgatca gctaaacgct gaatgatctc ttggcgcttt
    15661 tcacggtaat tgcctacatt gactactaca gacagcttat ttcttgctaa acgatggatg
    15721 aagacttgtg ccagatattg caatgcattc agtgtttttc catgtttccc aatcagtatg
    15781 ccttgctttt gtgtttctaa atggaaaaca accatattat ttgattctct ttccattttg
    15841 acaagagctg gagcatcaag ctgttttgaa atttcagtaa gataaactgc caattccgtt
    15901 aaagctgctt catcacctag ctcacttact tcttctgttt tttcttcaag aatcgtttcg
    15961 ttgactacct cgatctcagc tgttggttct tcttccaaaa tttcttctac agtctgttct
    16021 actgtttcag aaactttttc gctgatactt ggctggatcg aaagccgtgc attctttcga
    16081 cccattccta ggaaaccttt ttttccttct tccagtattt cgatttcgac ttggtctttg
    16141 gccaaaccca aatcagccag acctagttgg acagcttcgt ctattgttgc agcttcataa
    16201 atcggcatta gcattacctc ccctattatt tccgtttttt cttaggattc attgctttct
    16261 taagagcacg ttctctttcg cggattctcc gtgcttcttc ttcacgctct tttcgaattt
    16321 tgaaagggtt gttgatcagc agcgtttgta caacttggaa ggcattggaa actacccagt
    16381 ataatgaaag accgctggct aaattgacac ccatcactaa aatcattaca ggcatcacga
    16441 aattcatgat cttcattgat gcattcgatt caatttgact catgctagat aaatacgtac
    16501 ttgcaaaagt aaagattgct gctaaaatcg gcaaaataaa tgttggatcc gcgttcccta
    16561 agttcaacca taagaaatgc ccttgtttca actctggtac acgtgaaata gattgccata
    16621 acgccatcaa gattggcatt tgtactaata aaggaagaca accagcatat ggattgacgc
    16681 cattttctgc atataaacgc tgctgctctt ctcttaactt actttgtgtt tccggatctc
    16741 ttgaactata ttgttgctgc agtgctttta atttcggttg taattcttgc gttttacgca
    16801 tgctctttgt ttggaaatgc atcaacggca ataggatcac gcggatgatc agtgtaaata
    16861 aaatgatccc tatccctgca ttaccaaatg acaacgcctt gatcgcctca gcaaagtaat
    16921 aaacaatata acgatcccaa attcctgtac tctgtgcgct gacttcccca gttccgcaac
    16981 cggataagac gatgaccaaa ctaacgatac cggccatcaa aagtaaacgt ttgtatttct
    17041 tcacttactc ttttcctctc tgtcgattat ttttgcaagt tttaagacgt ggactaaatt
    17101 ggagcgaacc tcatcataag tcaacccctt cacacttggt ctagcaatca caataaaatc
    17161 caactccgga tcaatttctt cttttataga ataaactgct gctcggattt ttcgtttgac
    17221 ttcattgcgg tttaccgcgt tgccgacctt ttttcctaca gataaaccaa ctcgaaaatg
    17281 aggctgtccc ggtttttcca aacggtaaac gacgaatttg cggttagcaa aagaatctcc
    17341 cgtatggaac acggcttgaa actctcgttc tttttttact cgatacgctt ttctcattag
    17401 ttttctttcc ttttctatct ctcacttacg ctcataatca taccataatt acgattgtcc
    17461 tttcatcatt tccctaaaaa agagtataaa aaaaaccact gaaaccccag tggcctaagc
    17521 tgaaagaact tttcttcctt tgcgacgacg gctagctaac acacgacgtc catttttagt
    17581 actcatacgt ttacggaatc cgtgaacttt ttgacgttta cgtttatttg gttggtatgt
    17641 tcttttcata tattccacct ccaaaatgtt cttatctatt ttataaacac agacatactt
    17701 tgatagtata acgacaaagt agtgattttg tcaatataaa atagaagatc gattgttaaa
    17761 acttatccac aagattattt ttttctatgg gaatcctatg tggaaaaagt tatgcacagg
    17821 gattatccac agataataaa aggctggttt tacacagaaa acacacgtgt aaaaaaagta
    17881 atccacaatc aggcgatttc ctgtgtattc cgtctcctaa ctattggtat atctgtattt
    17941 tttatccaca gacgcaagag gaaatctatt ggtttttacg agttttccac ctgtgcatta
    18001 gtggtgtgga aaactttttt tgacaactgt gtttttctct tttttctttt tgtcgattgt
    18061 gtggataatt gtaattaaaa aatttttttc ttcggtttct gtggaaaact attgaaaaaa
    18121 atgctaaatt agtactagtt attcactttt taatgaagga ggaggcctta tatggtatcc
    18181 ctcgatgctt tatggaatga attaaaagca acataccaaa aggatttatc gcctgctagc
    18241 tataatacat ggatcgaaac agcgaaccct cgaacccttg atcaaaacca gctcgttgtt
    18301 gaggttccta gcaagattca taaagaatat tgggaaaaaa acctggcgac aaaaatcgtt
    18361 gaagtcggtt atatgttatc aggaaatgag attatccctc gctttattac tggcgaagaa
    18421 gcagagcaag aagaagttat agaagaaaaa aatccaaaag ttgtggcacc tagtccgcta
    18481 aaaaaagcca tgctgaaccc taaatatacc tttgatacgt ttgtcattgg taaaggaaac
    18541 cagatggctc atgcagcagc gctcgttgta gcagaagatc caggttctat ttataacccg
    18601 ctcttctttt atggaggcgt gggacttggt aagactcact tgatgcatgc aattggtcat
    18661 caaatgctgc aaagtcagcc taatgccaaa gtaaaatatg taagcagtga aacttttgct
    18721 aatgatttca tcaattcgat ccaaaacaaa acagcagaag agttccgtca agaatatcga
    18781 aatgttgatt tactgctagt ggatgacatt caattttttg cagaaaaaga agctacgcaa
    18841 gaagagtttt tccatacttt caatgccttg tacaatgaag ggaaacaaat cgtactaacc
    18901 agtgatcggt tgccaaacga gattccgaaa ctgcaagaac gccttgtttc tcgctttgca
    18961 tgggggctgt ctgttgatat tacaccgccg gatcttgaaa caagaacagc gattttacgt
    19021 aaaaaagcgg cggctgaacg tctagagatc ccagatgaca cactaagcta catcgcagga
    19081 caaattgatt ctaacattcg tgaattagaa ggtgcgcttg ttcgagtgca agcttttgct
    19141 gcgatgaata gtgaagatat ttcgactagt ctagctgcag acgcactgaa aacgttaaaa
    19201 tcaggaaaag gacatcctca attgtcaatc ctgcagatcc aagaagaagt ggcaaagtat
    19261 tatcacatcc aattgaaaga tctcaaagga aagaaacgcg tcaaatctat tgttgttcct
    19321 agacaaatcg ctatgtattt ggcacgtgag ctcacagata attctttacc gaaaatcgga
    19381 gctgaattcg gtggcaagga tcatacaacg gttatccatg ctcatgaaaa aatccagcag
    19441 ctgatggatt ctagtgtcag tatgcaaaat gaagtatcag aaatcaaaaa ctttttacta
    19501 aattaatttg tcgattctat caactgaaaa tagcatgtgg ataaaagaaa aaaacgttca
    19561 aaagttatac acactttttc cacagctgtt ttttcgtttc tctcttacgt tttttgagtt
    19621 ttccacagaa tcaacatgcc ctattacttt tattattctt tttaactaat aataaataaa
    19681 caaacattca aaggagatac atcatgaaag ttactttaaa ccgagctagc tttatgcagg
    19741 aattgcaaac tgttcaacga gctatttcaa gcaaaaccac gatccctatt ttgacaggtg
    19801 taaaaatcac actgacacaa gaaggtttga ctttgacggg gagcaacgct gatatatcaa
    19861 ttgaaacttt tttgtctgtt gaaaacgaaa aagcaaatat gcaaatcgaa tctactggtt
    19921 ccattgtttt acaagcacgt ttctttagcg aaatcattcg gagacttcct gaagaaacat
    19981 ttactttaga agttttagaa aataaacaag tagcgatcac ttctggaaaa gcgaatttta
    20041 tcgtaaatgg attagatgca gataactatc ctcatcttcc tgttgtcgaa agccataacc
    20101 agatgaaatt acctgtacac gtattgacta aactaatcaa cgaaacagtt tttgctgtct
    20161 cacaacatga gagtcgtcca atcttgacag gtgtgcattt cattttatct gataattctt
    20221 tattagctgt agctactgat tctcaccgtc taagtcaacg cgtgattcca gtagaacaag
    20281 cggctgatca ttttgatatt gttattcctg gaaaaagttt gatcgaatta tctcgctcat
    20341 taacaaatga agaagaaatc gtcgaaatca gcattatgga aaaccaagtg ttgttcaaaa
    20401 cagaaacgat gtatttctat tcccgtttgc tagaaggaaa ctatccagat accaatcgtt
    20461 tgattccttc aagttttaat acagaggttg aattttctgt tcctagcttt ttagcggcga
    20521 tcgaacgggc ttctttactt tctcatgaag gccgtaacaa catcgttcgt ttatctattc
    20581 gtccagatgc ggttgtttta tacggaaatt cgccagaaat cgggaaagta gaagaaagct
    20641 tgagttatac agcaagcagt ggcgatccat tagatatttc tttcaatccg gattatatga
    20701 aagcagcgtt gcgtgcattt ggagatatga gcatcaaagt gaaatttatc tctgctattc
    20761 gtccatttac attggaacca acggaagatg gcgttcaatt tattcagctg attactcctg
    20821 tacgtacaaa ttaacaatga ttttcaatgt tcttgaaaat ttaattgaaa agaaatagaa
    20881 aaaataaaat tttaaacaga aggccctaaa atctctttta aggctttctg tttatttttg
    20941 tttaaatcac cttttttaga ttaaatcgtc ttatatggaa aaatatatgg ataaatttgt
    21001 tttattgcga aaaaaaaggt ataatagagt atacttttaa taatgaaaat gagggatggg
    21061 cattgaaaca acaagtcatt ctaaatacgg aattcatgac gttgggccaa atgttgaaag
    21121 aagtcacagt tatcggtagt ggcggacaag caaaatggta tttggcagaa aacactgtgt
    21181 tagtcgatgg cgaaccagaa aatcgtcgtg gacgcaaact ttatcccggc atgatggttg
    21241 aagttccaga agtaggaact ttttttatgg taaaaaaagg aaacgacgat aatgaggctg
    21301 aataagctgt atttaaaaaa ttatcgaaat tacgaagagc tgaacatcga attttccaag
    21361 aacctcgtca tctttttagg agaaaatgcg caaggaaaaa cgaatctttt ggaaagtatc
    21421 tacgtattag ctatgacgcg aagtcatcgg acaagtagtg agcaggaatt gattggctgg
    21481 actgacgatc aggcgatgat tcaaggagag atcacaaaag gttcatccac tcttccatta
    21541 gaaatcttat tatctaaaaa aggccgaaaa accaagatca accatatcga acagaaaaag
    21601 ttaagtactt acgtgggaca aatgaatgtc attttatttg caccagaaga tctttcttta
    21661 gtaaaaggca gcccgcagat caggcggaag tttttagata tggaattagg ccagatcaat
    21721 ccaatctatc tttatgatct tgtccaatac caagcaattt tgaaacaaag aaaccagtac
    21781 ttgaagcaat tgaatgaaaa aaaacaaact gatttgcttt atttggatat tttgtccgaa
    21841 caactagcag cgtttggcag caaagtattg aaagcaagag cacagttcgt caagcgattg
    21901 gagttttggg ctaattcttt gcatcagcaa atcacccatc aaaaagagca gctggaaatc
    21961 gagtatctca ccgcagtcga ttctttagaa acacatacgc aagagcaaat ccaagaacaa
    22021 tttctcgcac ttttgaacca aaataaaaag aaagaccttt ttcggggaac aacgacagtt
    22081 ggtcctcatc gtgacgatct ttcctttttt attaatcaga aaaatgtgca gacttatgga
    22141 tcgcaaggac agcaaagaac aactgcacta agtgtcaaat tagcagaaat cgatttgatt
    22201 aaagaagaga caggggaata tccaatcctt ttgttagatg atgtgatgag cgagctggat
    22261 gataatcgtc aactccatct gctagaaaca atcgaaggaa aagttcaaac gttcttaaca
    22321 acaacgacac ttgaccatgt aaaaaataaa atgactgttg aacctgagat tttttatgtt
    22381 caacaaggga aactaaaagg agaagaaact gaatgacaga agaaagaagt ttagtagaac
    22441 gcgctaaaga gtatgatgcc agtcagattc aagtacttga aggacttgaa gccgttcgta
    22501 aacgacctgg catgtatatc ggttcgacta gttctgaggg tctgcatcac cttgtttggg
    22561 aaattgtcga taattcgatc gatgaagtat tagcaggttt tgcaacgaaa atccatgtga
    22621 ttattgaaaa agacaacagt atcaccgtta ttgacgacgg tcgggggata cctgtagata
    22681 tccaggcaaa aactggacgt cctgcagttg aaacggtctt tactgtttta catgctggag
    22741 gaaaattcgg cggtggtggg tacaaagttt ctggtggact tcacggagta ggatcttctg
    22801 ttgtaaacgc gctttctaca cagcttgatg tcaaagtata caaagaagga aatgtgtact
    22861 atcaagaata tcgtcgtgga gctgtagtgg acgacttaaa gattatcgaa caaacggatc
    22921 gccatggaac aacggttcac tttacgccag accctgaaat ttttacagag acaactgagt
    22981 ttgatttttc aaaattggct acccggatcc gtgaacttgc tttcttgaac cgcgggatgc
    23041 gtatatcgat tgaagacaaa cgagaagaag aaccagtcat caatgaatac cattatgacg
    23101 gcgggatcaa aagttatgtc gaatacttga atgcaaacaa aaccgtgatt tttccagaac
    23161 ctgtatattt ggaaggtgaa cagcaagata tcgcagttga agtctctatg caatatacag
    23221 acggctacca ttccaatatc atgagttttg ccaacaatat ccatacgtat gaaggtggaa
    23281 cacatgaatc aggattcaag actgctttaa ctcgtgtgat aaatgattat gcccgaaaac
    23341 aaaagctgat gaaagaaaat gacgacaact tgaccggtga agacgtgcga gaaggattga
    23401 cagctgttat ttctatcaag catcctgacc ctcaattcga aggacaaaca aaaacaaaat
    23461 tgggcaattc cgaagtacgg acagtcactg atcggttatt tagcgaacat ttcatgaaat
    23521 tcttgctgga aaacccaagt gtgggccggc aaattgttga aaaaggatta ctagcttcca
    23581 gagctcgtct agcagcgaaa cgtgcgcgtg aagtaacgag acgtaaaggt gctttagaga
    23641 ttagtaatct gccaggaaaa ttagcggact gctctagcaa cgatcctgaa aaatgcgaat
    23701 tgttcatcgt cgaaggagat tcggccggcg gatcagctaa gcaaggtcgt aatcgagagt
    23761 ttcaagccat cttgcctatt cgtgggaaaa tcttgaatgt tgaaaaagca agcatggaca
    23821 agatcttggc aaatgaagag atccggtctt tatttactgc tatgggtaca gggtttggag
    23881 aagattttga tgtatcgaaa gctcgctacc acaaattagt tatcatgact gatgccgatg
    23941 tcgacggcgc gcatatccgt acattgctgc tgactctttt ttatcgttac atgcgtccta
    24001 ttgttgaagc tggatacgtc tatattgctc agccaccttt atacggggta aaacaaggga
    24061 agaatattac gtatgtacaa ccaggaaaaa atgcagaaga agagttgaaa caagtcgttg
    24121 cttcacttcc tgcctcacca aaaccaagcg ttcagcgtta taaaggactt ggagaaatgg
    24181 atgatcatca actatgggaa acaactatgg acccaagcaa tcggatgatg gcccgcgtca
    24241 gtgtggacga tgctattgca gcagatcaga tatttgaaat gttgatgggg gatcgagtag
    24301 aaccccgtcg tgcattcatc gaggaaaatg cacactatgt gaagaactta gatatttaat
    24361 catgaaggag gaaaaagaat gagtgaagaa atcagagaaa acatccatga tgtcaatcta
    24421 accagcgaaa tgaaagactc cttcatcgat tatgcgatga gtgttattgt cgcacgtgca
    24481 cttcctgatg tcagagatgg tctgaaaccc gttcatcgcc gtattttata cggcatgaac
    24541 gaattaggtg taacaccgga taaagcccat aaaaaatctg ccagaatcgt cggagatgtc
    24601 atgggtaaat accatcctca tggagacatt gcgatctatg agtcaatggt acggatggca
    24661 cagccattca gctaccgtta tatgctagtg gatggtcatg gaaactttgg ttctgttgac
    24721 ggtgacggtg ccgccgctat gcgttatacc gaagcacgga tgagcaaaat cgctacagaa
    24781 atgctgcgtg atatcaataa gaacactgtt gatttccaaa gcaactatga tgatacagaa
    24841 aaagaaccag ttgtactacc tgctcgcttc ccgaatcttt tagtgaacgg aacaacgggg
    24901 atcgccgtag gtatggccac gaatatccca cctcataact tgtctgaggt agtagcggct
    24961 atcgatttgc tgatggataa tcctgatgtg acgaccaatg aattgatgga agtattacct
    25021 ggaccagatt ttccaacagg tggtttggtt atggggaaat caggaatccg aagagcgtat
    25081 gaaacaggta agggttctat taccgtacgt gcaaaagttg agattactga gatgccaaat
    25141 ggtaaagaac ggatcatcgt gacagaattg ccttatatgg tcaataaagc aaaattgatc
    25201 gaacggattt ctgaactgca cagagacaag cgtatcgaag ggatcacaga tttgcgggac
    25261 gaatcttccc gtgaaggtat gcggatcgtc attgacatcc gtcgtgacgc cagcgcatcc
    25321 gttatcttga ataacttata taaattgaca tccttgcaaa attcatttgg attcaatatg
    25381 ttggcgatcg aaaaaggtgt gccgaaagtt ttgagcttga aacaaatcct tgaaaactat
    25441 atcgaacatc aacgcgaagt catcacacga cggacggtct ttgaaaaaga aaaagcagaa
    25501 gcaagagcac acatcttaga aggtttgcgt attgctttgg atcatatcga tgaaatcatt
    25561 gcgattatcc gcgggtctaa atcagatgac gaggcaaaag caacaatgat cgaacggttc
    25621 gatttatccg atcgccagtc tcaagctatt ttagatatgc gtttacgccg attgaccggt
    25681 ttggaacggg aaaaaatcga aaatgaatac caagaactct taaaactgat tgaagattta
    25741 actgacattc tggcaagacc agaacgtgtt acagaaatca tcaagaatga attagcagac
    25801 ttgaatcaac gatttggtga taaacgacgc acagaattac tagtcggtga ggtcttaagt
    25861 ctggaagatg aagatttaat cgaagaagaa gaaatcgtta ttacattgac aaacaatggt
    25921 tacatcaaac gtttggcaaa taatgaattc agagctcaac gaaggggtgg acgtggtgtc
    25981 caaggaatgg gtatccacaa tgacgacttc gtcaaaaatc tggtttcttg ttctacccat
    26041 gatacattgt tattctttac gaataacgga aaagtgtatc gggcaaaagg atacgaaatt
    26101 ccagaatacg ggcgtacagc caaaggaatc ccaatcatca atttactagg tatcgattcg
    26161 agtgaaagca tccaggcaat cattgcggtg acgggagaag cagaagaagg ccactatctc
    26221 ttctttacga cgcgtcaagg tacagtaaaa cgtacttctg tcactgcttt tgctaacatc
    26281 cgaagtaatg gtctgatcgc aattggtttg aaagaagacg atgagctcgt caatgtgcta
    26341 ctgacagatg gtcaatctaa tatcattatt ggaacacata acggctactc tgtcactttc
    26401 aaagaagaag cagtccgcga tatgggacgt acagcttccg gggtcagagg gatacgcctg
    26461 cgtgaggaag attatgtcgt tggggcagcc ttaatgaagg aaaatcaaga agtattagtg
    26521 atcacagaaa aaggttacgg aaaacggaca aaagtatcgg aatatccagt gaaaggccgc
    26581 ggaggtaaag ggatcaaaac ggcgaacatc actgaaaaaa atggtccact agctggattg
    26641 accactgttt ctggagatga agacatcatg ctgattacag ataaaggtgt cattatccgt
    26701 ttcaacgtat cgactgtttc tcaaactgga cgttcaacat taggcgtacg tttgatgaag
    26761 atggaagctg atacgaaagt tgtcacgatg gcagcagtcg aaccagaagc tgcagaacaa
    26821 acagttgaag aacaaggatc agaagaataa ccatcaagac taagtgtgta agctagcaag
    26881 aataaccgat taaaaaatct ggttattcct gctggctttt ttgattagtt gaatttctct
    26941 taaaatattc gaaactgttc attctgtatt gcttttgacc aaaatagagt gtataattag
    27001 agcttgtgag tagtctaatt aattagataa ctctccttgc tcttaggaac ctaagagccg
    27061 aaagtccaca gggaggtgaa tatcaatgga aaacacgaaa tatgaaatca tgtacattat
    27121 tcgtccaaac attgatgaag aagcaaaaac tgctttaatc gaacgtttcg atgcaatctt
    27181 gaaagataac ggagcagaag ttatcgaatc aaaagattgg gaaaaacgcc gtttcgctta
    27241 tgaaatgaac ggttaccgtg aaggtatcta tcacatcgtt aaagtatctt ctccatcatc
    27301 agcaaatgct gtcaatgaat ttgaccgtct tgctaaaatc aacgacgata tcattcgtca
    27361 catgattgtt aaagaagaag cttaattgtt gtttcatgtg aaacaataga aaacgatgag
    27421 aggagatgac tattttgatt aataatgttg tattagttgg acgtctgacg aaagatccag
    27481 atttgcgtta cacagcaagt ggtacggcag tcgcaacatt tactttggct gtgaatcgta
    27541 attttacaaa ccaaagcggc aatcgcgagg ctgattttat caactgtgtg atttggcgca
    27601 aatcagcaga aactttagca aactatgctc gtaaaggaac acttttaggt gttactggac
    27661 gtatccaaac tcgttcttat gataatcagc aaggacaacg tgtatacgtg acagaagtag
    27721 tagctgacaa cttccaattg ctggaaagtc gttctgcatc tgaaaatcgc caacaaagcg
    27781 gcggattcca aagttctggt caatcagctg gcggatttgg cggaaacaat aactctaatc
    27841 aaacatctca atcatccaac ggtatgcctg atttcgaccg tgatacttct gacccattcg
    27901 gctcaagttc aacgatcgac atttcagacg atgatttacc attctaaacg aatttgatag
    27961 gagggaaata gaatggcaca acaaagaaga ggcggacgta aacgtcgtaa agtagactac
    28021 attgctgcta accatattga atatatcgat tataaagata tcgaattact aaaaagattt
    28081 atttcagaac gcggtaaaat cttgccacgt cgtgtaactg gtacaggcgc taaaaaccaa
    28141 cgtaaaatta ctgttgcaat caaacgcgct cgtatcatgg gcttgctacc tttcgttagc
    28201 gaagactaat aaatcctagg aattgaatga ctgatccttt tgatcagcta ttcaattcct
    28261 ttttttctgt aaaaataacc tctattcgtt tagtcgctcg aatgacgaaa gttatggtaa
    28321 aatcaaatta gtcatatatg ggaggaaaat tatggaaaat aaaaacaatc atttatcccc
    28381 gaaacctctc ttccttatcc tgtttatatt aatcgaagta ttggtagtct taattttacc
    28441 atttcgtttt gttagcgctt cggtcattct attgatgaat ttatggggtg ttcgctattg
    28501 gttgaaaatg aaacgttggc ttattttaaa taaacgtgaa aaaatccagc aggcttcgac
    28561 tgtagctgaa accaatctag cttatgtctc agaagtcatg cctgtaggag tgattgctta
    28621 tcagccatca agccaaaaaa tcgaatggct caatccatta gcattgaaaa tcaaagatca
    28681 aagtggatta acagaggaag aattgctaga tacttttttt actgcaaaag aaaaaaagaa
    28741 aaaccaagtc tatctagcag ataaaacatt tcagtttgat atggatacag taaagggtgt
    28801 tgtttatttt aatgatatta cccaaaacca gttgttaaaa ctccatcaga cgaacagtca
    28861 gccggtgatt ggtattttat ctattgataa ctatgcagat gccattgata aattagatga
    28921 caaagagatt tcttatttga actctttcgt cactacacta gtttctgact ggatgaatga
    28981 ataccatgtc tttttcaaaa gaatcaacgc agaacggttt ttcttcgtag cacagatgat
    29041 cgatctgaaa aagatgatgg ataaaaaatt tgatttgctg gatcgctttc gagcagaagc
    29101 tgaaaaacag agctcgccta tcacccttag tatggggatt gcttatggct caagaaccct
    29161 cgatgaaatc ggtggagaag ctcagaataa tttagatgtt gctttagtcc gtggaggcga
    29221 ccaagttgtc gtgaaagagg taaaagaagg agcaaaacct gtttattatg gggggaaatc
    29281 tgctaagaat gtcaaacgca cgcgtgttcg ttctcgagcg atgagtaccg ctttgcgtcg
    29341 gatttttgat gaaacaggcg atgtgtttat catggggcac aagtttccgg atatggatgc
    29401 tttaggctct gcttttggtg tcagttgtct ggcacgcttc aaccagaaaa aagcttacat
    29461 cgttatcaat gagaacgaga tcattccaga tgtagaacgg tgtcttgaag aaatccataa
    29521 gcatcctgaa ttagaaatgc aactaatctc tccagaacgt gccatagagc tgaaaaaaga
    29581 agaggacctc ctcgtgatgg tggattacca taaaccttct ctatcgatct ctcagggcct
    29641 atatgagcaa tttgataaga ttgtgatcat tgatcaccat cgtcgtgggg aagagtttcc
    29701 aagtaaacct ctgctgactt atattgaatc ttcagcttct tcagcttcag agctagtttc
    29761 tgagctgatc caataccaaa gcagcaaaac aaatcgctta gatcgttttg aggccacatt
    29821 attgcttgca gggatggttg tagatacaaa tagtttcaat gtccgtacaa ctgcacgaac
    29881 ttttgacgtt gccagctatt taaggtcttg tggagcagac gcatccttag tacaatattt
    29941 attgagctcg gatttagcga catacttgga gatcagcaat ttgattgctg gaagcgacta
    30001 tgtgacttct gatattgttg tggcggcagg gacagacgaa aaagagtata atagtgttat
    30061 agcagcaaaa acagcagata cattgctttc gatgatcaat atcaatgcag ctttcgtcat
    30121 tacaaagcgg acagacggct tgattgggat cagtgccaga agtaccggca cgatcaacgt
    30181 ccaaatcatc atggaatcct taggtggcgg aggacacttc acaaacgcag ctactcaact
    30241 ggaaaatacg acagttgagg aaacaaaaca gaagctattt gctgcaatca aagaaaatat
    30301 gaatcaaata tatgataagg agtaatccaa atgaaagtaa tttttttaca agatgtaaaa
    30361 ggaaaaggta aaaaagggga catcaaagaa gttccagcag gttatgcaca aaattatcta
    30421 atcaaaaata acttggcaaa agaagcaacg aaaagcagta tcagtcagtt agcaggacaa
    30481 aagaaagcac aagaaaaaca cgaagctgaa atcttggaag aagctaaaaa gttaaaagaa
    30541 ttcttggaaa aagaagatac tgtagtcgaa ttgaaggcga aagcagggga agacagccgt
    30601 ttgtttggtt cgatcccttc aaaacaaatt gctgaagggt taaacaaaca atacaaaatc
    30661 aaattagata aacgaaaaat cgaattagaa aatccgatcc gttcactagg ctacacaaac
    30721 gtacctgtta agcttcatca tgaggtgacg gctacgatca aagttcatgt cgtacaagaa
    30781 taacaaatct tgatagcgat gttcagctgg taagtataac cagaaggaaa aaagacaaac
    30841 cgaaatttat ctgagaaaac agctgcagca atgaaagcaa aagctgcaaa tcgatttcag
    30901 attgatttcg gtttcttttt tgggaacagc aaaatagcat aaagaaaacg agtataataa
    30961 aagagaacta tttttttatt acactttcgg tacgaatgat gacttttctc tcattttctt
    31021 gtaaaatgaa gcaattgaag acaaggagcg atacgtatga atgaagtgtg gcaggatcga
    31081 atcccaccgc aaaatattga agctgaacaa gcggttttag gctctgtttt tcttgacgca
    31141 gaaacgatca ttgatgccat ggagtacata gagccaaaag acttttatcg tcgtggccat
    31201 caaattattt ttgagacaat gatcgagtta aatgatcgta atgaagcgat tgacgtggtt
    31261 actgtcaaag accggctgga acaagccaat ttgttagaag atgccggtgg tttaagttat
    31321 ctctcagact tggcattagc agttccgaca gcagcaaata tcgtctacta tgcgaaaatc
    31381 gttgaagaaa aatcattgct gcgtacattg atccagacag caacaggaat cgttacgaaa
    31441 ggattcgagc aaggagaaga agttcaaaca attttagatg atgccgaacg cagtatcttg
    31501 gaggtttcgg aaaaaagaaa tcgaagcggc tttttatcta ttgctgaagt actgaactcc
    31561 acgattgaaa atatcgatcg actagctcaa aacaatgaag aaatcacagg tctaccaact
    31621 ggctatcaag gtctggataa aatgacagca ggtttccagc ccgaagaact aatcattctt
    31681 gctgcacgtc cagcggtagg taaaacagcg tttgcattga atattgctca aaatgtagga
    31741 acaaaaacag atcgttctgt tgcgatattt agtttggaaa tgggggcaga atctcttgta
    31801 aatcggatgc tttgtgcaga aggttcgatt gaggccagcc atttacgtac aggtcagctt
    31861 tcggaagaag aatggtcgaa tctgatcgtt gcgatgggga gtctttctcg agcaaatatt
    31921 tttatcgatg atacaccagg gatcaaaatc tctgaaatcc gtgcgaaatg tcggaaacta
    31981 gcgcaagaaa aaggcaatct aggcttgata ttgatcgatt atttgcagtt gattgaaggt
    32041 aacggtaaag agaaccgtca acaagaagta tcagatatct ctcgccaact gaaaaaactg
    32101 gcgaaagagc tgaaagtacc tgtcattgct ctttcacagt tatctcgtgg agtagaacag
    32161 cgacaagaca aacgaccagt gctaagtgat attcgtgaat ccggatcaat tgaacaagat
    32221 gcggacatcg tagccttctt gtatcgagat gattattatg aaagagaagg cggagatgac
    32281 gatgatggaa acgagccaaa aaatgacaac gtcatcgaag tcatcatcga gaagaaccga
    32341 agcggtgcac gaggaacagt tgaactactg tttatcaaag aatacaataa gttttcgtcg
    32401 ctttcgccaa gagaagaatt ttaaagaaga ggttgtgagc cttgagcaat cccgagagct
    32461 ctcgtaagaa gatgcaagga gtaaccgcag gaacgactag agtacttaat ttaaacagat
    32521 ctccaaaggg attgtgacaa aagtcttgtc acagtccctt tttccgaata aacggtgttc
    32581 aatcagctga cccttggtat tagctcagca aacgtcaaaa tatgaggaac tattttgacg
    32641 tttgtttctc taatactcag gtcaaaacgc tgatcttacg acctcttttc cttaaacggt
    32701 gttctcctgc caactcctcg gtcacaagtc acaatatcat caaacatgag aagcagtttt
    32761 ttgaaattgc tccttgtgac tcagagttaa acggcaggct cacaacctct ttcttaaacg
    32821 gtgttcaaaa gcttgcatct gcggtaatac gcccaatcaa acgaaaaata tgagaagcta
    32881 tttttgtttg gctgttctta ttacttgatg caggacagct ttttcacaac ctctgattca
    32941 cggtgttcca aaagtagctt cttcgaaaaa taagtcgaaa tttcacaaaa atttgagaag
    33001 caattttcgt acattccttc ttatttcttg aagctgacca cttctgttac aacctctttt
    33061 ttaataacca ttctaaaaag ataaagttcg ttttttaagc gtttttataa aataaaaata
    33121 aaaatcattc gattttattt gaaatatgta tctattattg atacaatggt tcaggattaa
    33181 ataatataga acgaggtgtt cacatgtcat ctgtagtagt agtaggtacg caatggggcg
    33241 atgaagggaa aggaaaaatc acagactttc tcagtgaaaa tgctgaagtg attgcacggt
    33301 accaaggtgg cgacaatgca gggcacacaa ttaagtttaa cggtgtgact tataaactgc
    33361 atttgattcc ttctgggatt ttttataaag acaagatcag tgtgatcgga aacggcgttg
    33421 tagtcaatcc taaatcattg gttaaagaat tagcttattt acatgaaaaa ggtgtagaaa
    33481 caagtaattt gcgtatttct gaccgcgcgc acgtaatctt gccttatcat atcaaattgg
    33541 accaattaca agaagatgct aagggcgaaa ataagattgg tacaacgatt aaaggaatcg
    33601 gacctgccta tatggataaa gcagctcgtg taggtatccg tattgcagac ttattagata
    33661 aagaaatttt tgaagaacgt cttcgtttga atctagatga caaaaaccgt caatttgtaa
    33721 aaatgtttga ttcagaacca cttgattttg acgatatttt tgaagaatat tatgaatacg
    33781 gacaacaaat caaacaatac gtcacagata cttccgttat cttgaatgat gctttggatg
    33841 caggcaaacg cgtgttgttt gaaggcgcac aaggtgtaat gctggatatc gaccagggaa
    33901 cttatccttt tgttacttct tctaacccag tagccggtgg ggtaacaatc ggaagcggtg
    33961 tagggccttc aaaaatcaat aaagttgtcg gcgtctgcaa agcctatacg tcacgtgtcg
    34021 gtgatggacc atttccaact gaattatttg atgaaacagg agaacaaatc cgcgaagtag
    34081 gacgagaata cggtacgaca actggtcgtc cgcgtcgtgt aggctggttt gattctgtag
    34141 ttatgcgcca ttctaaacga gtttcaggta ttaccaacct atctttaaac tcgatcgatg
    34201 tattaagtgg attggaaaca gtaaaaattt gtacggctta tgaattagat ggcgaactaa
    34261 tctaccacta tccagcaagc ttgaaagagt tgaaccgctg caaaccaatc tatgaagaat
    34321 tgccaggctg gtcagaagac attacaggat gcaaaacact tgcagaactg ccagaaaacg
    34381 cacgtaacta tgtacgtcgt atctcagagc ttgttggtgt acgtatctca acattttctg
    34441 tcggacctga tagaacacaa acaaacatct tagaaagcgt ctgggcgcaa atctaaggat
    34501 aaaaacgacg actgaatcag gacgttctta ccagagcgag tcgaagtgtt tatctatacg
    34561 ataataataa cttgaagagg tagtgaaaga gacgtttagc cttattgccg ataggctgtc
    34621 tcttgaacac tgtttattca gaataaggga ctgtgacaaa aaccgtgtca cagtcccttt
    34681 ttccgaa
//
LOCUS       DADLIO010000024        32686 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.024, whole genome shotgun sequence.
ACCESSION   DADLIO010000024 DADLIO010000000
VERSION     DADLIO010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32686
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.024"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            13..636
                     /locus_tag="JOX41_001308"
     CDS             13..636
                     /locus_tag="JOX41_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449064.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1086..2135
                     /locus_tag="JOX41_001309"
     CDS             1086..2135
                     /locus_tag="JOX41_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAY6449065.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2132..3013
                     /locus_tag="JOX41_001310"
     CDS             2132..3013
                     /locus_tag="JOX41_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAY6449066.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3016..3786
                     /locus_tag="JOX41_001311"
     CDS             3016..3786
                     /locus_tag="JOX41_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAY6449067.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4065..4919
                     /gene="aroE"
                     /locus_tag="JOX41_001312"
     CDS             4065..4919
                     /gene="aroE"
                     /locus_tag="JOX41_001312"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HAY6449068.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5097..6260
                     /locus_tag="JOX41_001313"
     CDS             5097..6260
                     /locus_tag="JOX41_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HAY6449069.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6377..6787
                     /locus_tag="JOX41_001314"
     CDS             6377..6787
                     /locus_tag="JOX41_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAY6449070.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6961..9189
                     /gene="topB"
                     /locus_tag="JOX41_001315"
     CDS             6961..9189
                     /gene="topB"
                     /locus_tag="JOX41_001315"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAY6449071.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9327..9644
                     /locus_tag="JOX41_001316"
     CDS             9327..9644
                     /locus_tag="JOX41_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449072.1"
                     /translation="MKKVHSFLNYLMGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAY
                     SPTLILSTLTAGAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQ
                     YFG"
     gene            9804..10040
                     /locus_tag="JOX41_001317"
     CDS             9804..10040
                     /locus_tag="JOX41_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAY6449073.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10037..10435
                     /locus_tag="JOX41_001318"
     CDS             10037..10435
                     /locus_tag="JOX41_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HAY6449074.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
     gene            complement(11102..12046)
                     /locus_tag="JOX41_001319"
     CDS             complement(11102..12046)
                     /locus_tag="JOX41_001319"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HAY6449075.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(12342..13286)
                     /locus_tag="JOX41_001320"
     CDS             complement(12342..13286)
                     /locus_tag="JOX41_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAY6449076.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            13506..14720
                     /locus_tag="JOX41_001321"
     CDS             13506..14720
                     /locus_tag="JOX41_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAY6449077.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            14742..16757
                     /locus_tag="JOX41_001322"
     CDS             14742..16757
                     /locus_tag="JOX41_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HAY6449078.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(16840..18213)
                     /locus_tag="JOX41_001323"
     CDS             complement(16840..18213)
                     /locus_tag="JOX41_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HAY6449079.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(18239..18523)
                     /locus_tag="JOX41_001324"
     CDS             complement(18239..18523)
                     /locus_tag="JOX41_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAY6449080.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(18525..20540)
                     /locus_tag="JOX41_001325"
     CDS             complement(18525..20540)
                     /locus_tag="JOX41_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAY6449081.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(20719..21024)
                     /locus_tag="JOX41_001326"
     CDS             complement(20719..21024)
                     /locus_tag="JOX41_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HAY6449082.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(21113..22143)
                     /locus_tag="JOX41_001327"
                     /pseudo
     CDS             complement(21113..22143)
                     /locus_tag="JOX41_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
     gene            22350..23225
                     /locus_tag="JOX41_001328"
     CDS             22350..23225
                     /locus_tag="JOX41_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAY6449083.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(23377..24219)
                     /locus_tag="JOX41_001329"
     CDS             complement(23377..24219)
                     /locus_tag="JOX41_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAY6449084.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(24311..26188)
                     /locus_tag="JOX41_001330"
     CDS             complement(24311..26188)
                     /locus_tag="JOX41_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAY6449085.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(26185..27606)
                     /locus_tag="JOX41_001331"
     CDS             complement(26185..27606)
                     /locus_tag="JOX41_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAY6449086.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(27609..30998)
                     /locus_tag="JOX41_001332"
     CDS             complement(27609..30998)
                     /locus_tag="JOX41_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HAY6449087.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            31255..32646
                     /locus_tag="JOX41_001333"
     CDS             31255..32646
                     /locus_tag="JOX41_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAY6449088.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
BASE COUNT        10089 a         5919 c         6264 g        10414 t
ORIGIN      
        1 gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat cgagagtaca agaaatgaat
       61 gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt attttcgacg tcttgttttt
      121 ctgctcatct tatcattgct gttaacagtt gcaatgtttt tattgccgga aaaaatccga
      181 gaagagcaag taaatagtct cgtttattcg tccataccaa ccagcaaatt gaaacctttt
      241 gattacagca aagctgatca gaaaatcaaa caaagccggg cgatatcggt gatgttcagc
      301 aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt ttaatgatcc tgagcttatg
      361 gaagaattga atcgaccgat cttttattat ccgatcgttt atgatgtaca tgaactggaa
      421 caaaaatata acatacgaac ggatgaagtg acatttattt tctttgatgg aggaaaagaa
      481 gcaaatcgga taactgcggg taagggagga ataactgatt ttgataagga gttgatccct
      541 gaactgaatc gacttccgtt agccaatatc aaacaattag aagaagaatt ggatagaacg
      601 ggagtaactt cccaaaattc cgagattgct aattgagaca ttggcgcgat gaaacggtgg
      661 gtctatatag cgctattttt aattatcaga acaagtgatg tttgatcttc aaaataacaa
      721 ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt cgattagact taaatcaatt
      781 cttaaggaaa gggtgacctg taatgaactt atcaaaacgt atttcagcag aaaacaaaaa
      841 aaattggcgc agctggcgta gataagttgt attaatggtg agactttccc atagatacaa
      901 ctttttagag tgcatttcta aagcttgtat ctatgctaga catgaacatt gactgccgca
      961 tagattagaa tctatgcggt tttttgtgta aagacaatga ccgctttggc cattgtcttt
     1021 ttttgtagac tggatacttg cctgattata ataaataaaa agattgactt tgcaggagga
     1081 aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat tattttagtt tatttagcag
     1141 gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag tacttcgacg aaccagacaa
     1201 aaaaaacaac agttgttggg gtattgcaat acgtgagcca tccggcatta gatgagattt
     1261 atcgaggaat caaagatggt ctgaaagaag aaggattaaa agaaggagaa aatcttgaga
     1321 tcaaatttca aaatggacaa gccgatcaga gcaagctagc cacaatgagt caacagctag
     1381 tacaatctga tccagatgcc ttgattggaa tcgcaacacc tgccgctcaa tcattagcaa
     1441 acacgacttc atcgatccca gttgtgttag gtgctgtaac ggatcctgtg ggggctggat
     1501 tagtcgcttc tttagagaaa cctggtggta atgtaacagg tgtttctgat cagccgcctg
     1561 ttacttcaca aatcaagctt gcttctgatt tgttgccaaa tgcaaaaaaa gtcggaatct
     1621 tgtatgcttc ttcagaggat aattcaaaat accaagtagc acaagcagaa gaagctgcaa
     1681 aaaaagaagg gttagaatca gtaaaatatg cggtgccttc cactaatgag attgcacaaa
     1741 cggttcaagt gatgagccga caagtcgatt ttatctatgt tccattagat aataccattg
     1801 ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc aaatatcccc gtcattccat
     1861 ctgtggatac aatggtggaa caaggtggac tagcaacaat cgggatcaat caatatcaat
     1921 tagggcttca aagcggtaag atggcggcag aacttgcgag tggaaaagaa aaaccggaaa
     1981 cgacgcctgt ttatacattt gatcaagggg atacagtgat caatcaatct caagctgatc
     2041 gcttaggaat cattgttccc caatcgatga aggaaaaagc caaaatcatt acagatgact
     2101 cgcagcaaga aacatctaag gaggatgaca aatgatcgta tcagctattt cacaaggcat
     2161 gctttgggca atattaggat tagggatttt catgacttat cggatcttag actttcctga
     2221 tatgacgaca gaagggtcct tcccattagg tgctgctgtc tgtgtgacag ctattactca
     2281 tggggtagcg ccgattgtag ctacattatt aggcgtaggt gctggcatga tagcaggact
     2341 cgttacgggg ttactttata caaaaggaaa gataccggtt attttagcag ggattttagt
     2401 gatgtcagga ttgaactcag ttattttgtt tgtgatgcga acaccaaatc tttctttatt
     2461 gaatcatccg attctacaag acagcttcca tcgctttggg ttacctgatt actttgacac
     2521 agtccttctt ggcttcatct ctttgggcat cttgattgct gtactgctat tcttcttcaa
     2581 tacagatttg ggtcaaggct atattgcgac aggagacaac gaaacgatgg ctcggtcgtt
     2641 agggataaaa accgatcgta tgaaaatttt aggtttaact ttgtcgaacg gtgtcattgc
     2701 attatccggt gcgctgattg cccagaacga cggatatgca gatgtaaata aagggattgg
     2761 cgtaatcgtc atcggtcttg cttccatcat catcggtgaa gtgatcttcc aagaattgac
     2821 gctagcagaa agattgattg ctattgttgt cggcagtatc atttatcagc tattgatttt
     2881 agtagtaatc aaactagggt ttgacacgac ttatctgaag ttgttctccg ctatcatctt
     2941 agctatttgt ctgatgatcc cgcaattgaa gaaagcactg aacttaaaaa cgggttttga
     3001 gaaggaggca tagtaatgac tgatatattg acaatcaaaa atggcagaaa agtcgtaaac
     3061 aatggaatga atgaagagaa agtactattg gatgaaatta accttacaat cagagaaggg
     3121 gacttcatca ctgtccttgg cgggaatggt gctggaaaaa gcacactgtt caatacgatc
     3181 gctggtacgc ttcaactcag tcaaggatcg atctctttta aagatcagct gatcacaaaa
     3241 gattcagaag aaaaaagagc acgattcctt tctcgagttt tccaagaccc caagatggga
     3301 acggctcctc ggatgacagt agcagaaaat ttgctacttg cacaaaaaag aggtcaaaaa
     3361 cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag attttttcag actatgtcaa
     3421 gaagtcggta atggcctaga gcaacacttg gatactccag cgggtgaatt atctggtggt
     3481 caacgccaag cattaagctt gctgatggcg acgatcacag ctcctgagtt actattatta
     3541 gatgaacata ctgcagcttt agatcctaaa acagctaaag cattaatgcg attaacaaat
     3601 cagcggatca atgaacaaaa attgacttgt ctcatgatca cgcatcgaat ggaagacgcc
     3661 ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga aaatcgttca agatatttct
     3721 gaaaaagaaa agcaacattt gacaatgggc gaccttttgc agttctttga agaagtagtg
     3781 gattgatttc gacagaaaaa ttcctttcag tagaaggact tgaaaactca ttgacatctt
     3841 cctttgattc atcctatact taaaacaata aacaattaaa catatttggg tgttttgtag
     3901 gatcacgtag tcaatgattt taacaattaa atagaatatt ctttgctctg acaagtaaac
     3961 gatgagaaaa gaatttgcta ctttgccacc tagacgtttc gtactttttc gtatcaaacg
     4021 ctaagtggct ttttttattg aagtaagaac aaaggaggaa taagatgatt tctggacaaa
     4081 ccaaattagc tgggctcttt gctgatccgg cttctcacag tttatcccca ttgatgcaca
     4141 atactgcttt tgaagcaaac aacatcgatg cggtgtattt agctttccaa gtaaatccaa
     4201 tgaatttgaa gcaagcagtc gaaagtattc gaacttttga tatgttaggt gtaaatcttt
     4261 cgatgccgaa taaaacagcg gttattcctt atctggatga ggtaagccag gaagcgcaat
     4321 tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg tttgattggc tataataccg
     4381 atggtgcggg cttcatgcaa tccgtgcaag aagctgggat ttcgatcaaa aagaaaaaaa
     4441 tgactctact gggagctgga ggtgcagcaa aggcagtcac tgttcaagct gcgttagacg
     4501 gcgctgagga aatcgtagtt tataaacgaa acaaccaaac attcgctcaa gtaaaagaaa
     4561 cattcgaaca actcagctat cgaacttctt gtaagataaa agttcgtgac tttgccgata
     4621 cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct agtcaatgca acagatatcg
     4681 ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat aagcatgatg catgagaatc
     4741 tagcggtttt tgatttgatt tatgcaccta gagaaacacg tttattaaaa gaagcaaaaa
     4801 aagtaggagc aaaaggatac aatggacttg gcatgttgat ctaccaagga gcaatcgcgt
     4861 ttgaattatg gacaaaggaa aagatgccga tccatgtgat tgaaaagctg tttgattaaa
     4921 aaaggataat agataaagat cttttattct cgcataaacg gtctcaagaa aagtaatcct
     4981 ttatgtatcg aagcatttat ttcgttattt tttattaaat tatcaaaaaa tgataggctt
     5041 ttgtcgattg gttatcgtat cctttattta tcagtaagaa acgaggagga accacaatga
     5101 gtcggatgga tcgctataag gacatccata agaaggcgaa acctctgaag cgggatacgg
     5161 ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat ggaaaatgag gaagatgcta
     5221 cccgtattta tgaaagagag cagcattcat ttgaacattt gaaccaatac gagcaacaga
     5281 tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa taaaaaattt ttcaatcggc
     5341 aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc gtggaaaaaa atcattctat
     5401 cgattttgct tgttttgatc ctttattcag gtatctcatt ttttattggt aaatatgtag
     5461 ctgaacatga cacaagctta gaggcagcga cttcagaaac ctttcatggg caaaaagcga
     5521 cgaatggtgc gcataatatt ttgatccttg gaagtgatac acgcggagaa gatgccgggc
     5581 gagccgatac gatcatggtc ttacagttgg atggtccttc ccataagccg aaactgattt
     5641 cttttatgcg tgacagcttc gttacgatcc caggggtagg acaaaataag atcaattcag
     5701 cttatgcata cggaggagcc gatctagtgc gtcaaacttt agtagaaaat tttggaatcg
     5761 attgtcaata ctatgcgaaa gtcgatttca aatcgtttga aaaagtgatc gatgccttat
     5821 tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa tctggatggt gtagatatta
     5881 aaaaaggggt ccagaagatg gatggacatg ttcttttgca gtacgcacgt ttccgaatgg
     5941 atgaacaagg agactttggc cgtgtcagac gccaacagca agtaatgaac gctattttca
     6001 gccaattgaa gaatccattg aatctgatcc gtgcacctta tgcagctggt aaagctttag
     6061 gatatacatc cacagatgtc actgcttggt tcttgacgaa aaacctcttt tcgattgcac
     6121 gaggagctgg tggcattgat cgaataagtg tgccagtaga cggttcgtgg aattatgggc
     6181 aaagtgatta tgctggcagt attcttgaaa ttgataatca aatgaatcaa tctgctatta
     6241 cagatttttt gaataaatga tcataaaaaa gatcaagaag aagctgcgca aggcttttgt
     6301 catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc ttatggtaga tttaaccaag
     6361 agaggagctg tttacattgg atatctatct gaacttcaaa aatgagtcgc gtgaagccat
     6421 cgctttttat gaaaaagttt ttcagactga agcatcaggt atcaccacat acggtgaaat
     6481 gcctggaata gaacaaatga acttgccaga agaagcaaaa aatctaatca cgaatgcacg
     6541 gctgaacatt tatgatacat tagttatgtt tgcagatacg ccagaaggaa ttggtcctga
     6601 attagttgtg ggaaataatg tttctttagt catccagaca agaaatgaag aagaaacgaa
     6661 gcgcctattt gaaagcttag ctgagggtgg taagattgag atgccactgg atgctgttcc
     6721 gtgggctcag ttgtatggga tggtaactga tcgatttggc atcaactggc agattaacca
     6781 agagtgacag ctaaagatga atattttctg gaaacatcaa gcagcaaacg gatcatcgtt
     6841 tgtttgcttg atgtttttgt gtctatttcg actatacggt atcttttttt tattgccaga
     6901 tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat taagtaacgg aggtcagaag
     6961 atgaagacgg tgatactagc tgaaaaacct tcacaagcaa aagcctatgc cgaaaccttc
     7021 caacagcaaa agcggcatga agggtattat gaaatcagcg atccattgtt tgctggtgaa
     7081 gtaaccatca cttatggttt tggacatttg gtagatatgg ttgctccagg agcttatgaa
     7141 gagcgttggg caaaatggtc tttagaaaat ttgcctattt tcccagaaac cttccgttac
     7201 gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa aacgagaatt gcagtcagcc
     7261 gataccatca ttattgcaac agatggtgat cgagaaggtg aagccatcgc gtggtcgatt
     7321 attcgacaag caaacgcatt ttctaaggaa aagaactatt tacgtttatg gatcaattct
     7381 cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc aacctggaaa gaactatttt
     7441 ccaaaatata aagaagcgca agcaaggcag aacgctgatt ggctgattgg aatgaatgga
     7501 agtccattat atagcttgct acttcaacga aaagggattg atggcagttt ttctcttggt
     7561 cgtgtacaaa caccgacact ctatatgatt tatcagctgc aagaagaaat caaacacttc
     7621 aaaaaagaaa cgtactttga aggagaaggt ttaattacga caaacaaagg gcagttttct
     7681 ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag agttaacgaa ggaaatagaa
     7741 aaacttggag cgcatttagg taagcaaaac ggacggattc ttgaagttac gaaaaaggaa
     7801 aagaggttgc atagtccacg tttattttcg ctatctagtt tgcagacaaa gatgaatcag
     7861 ctaatgaaag caagtgccaa agctacactt gatgctgctc aaggattgta cgaaagcaag
     7921 tttctaagct atccaagaac ggattccttt tacattacag aaaatgagca tcagtatctg
     7981 gttaaacatc tgcaaaatta taaaaaattt ttaggaatag aagaagtaca gacaactgag
     8041 atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc aagaacatca tgcaattatt
     8101 ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc tttccaaatt acagcaagca
     8161 atctatttgc aagttttgcg cactactgtg gctatgtttg ctgcagatta tatctacgaa
     8221 gagacgaccg taatgacggg cgtacagcaa ttaaagctaa aaagcatcgg aaagatccca
     8281 ttacagcaag gttggcagga aatcttacgc atcaagtcaa aaaagaaaga agctcagact
     8341 cttcctccta tcgtagaaaa tgaagaagca gaagtagaac tgaaaagtat ggagaaagaa
     8401 acacaacctc caaaacccta taccgaagga acgttgatca cagcaatgaa aactgcggga
     8461 aaaacgctgg ataatgatga agcgcaagaa attctcaaag aagtagaagg aatagggaca
     8521 gaagctacac gagccaatat cattgaaaat cttaagcaga agcattacat cgaagtcaat
     8581 aaaaacgaaa taactgttac gccaaaagga atcactcttt gtaaggcagt agccaatgaa
     8641 ccattactga cgagcgcaga aatgactgcg cgctgggaag ggtacttgag aaaaattggt
     8701 aaacaagagg ggacaccatc tgttttttta gagaatatca aaaaattcat cctacattta
     8761 ttggcagaag ttcctaatca aatcgacaag gtagactttt cagatgagat tagcgggaca
     8821 cgtcagataa aagcgatgga gaagaaaaac gatcaattag gaagatgtcc aaaatgtaaa
     8881 aagggaatag tcatgcttta tcctaaaatc gctacatgct tgaatccgga atgcgacttc
     8941 aaattgtggc caacagtagc taaaaagaag ctgactaaaa cgaatctcag agatttgctt
     9001 tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg gtaaaaaagg gaaattcgat
     9061 gcagttttag tattaaaaga agatatgaca atcggttttt cttttccatg gatcgaaaac
     9121 agtggaacaa aagcagttga tggaaacaaa gaaacatcaa gaaaaaataa tgaaaacgaa
     9181 gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt ccgaaaagtg agaatataaa
     9241 taccaataaa actaaaaaat atcagtgaat caagcaaaaa cgttggggta ggctgatttt
     9301 atatagatag caaggagttt ttttatttga aaaaagtgca ttcattttta aattatctta
     9361 tgggagcaat cacgattgtg gctgtgtacc aagcatttct aaagtatcct gattacggga
     9421 cgaagttgtt gtcattgacg cacaatcaaa cagcatattc accaacgttg attttatcga
     9481 ctttgactgc aggagctaaa agcgctactt atttttttca taaaacgaca agcatgctaa
     9541 agcgaaagaa acagcgaaaa caattgttgg tggtggtagc ggctatgatc attatttatt
     9601 ttctaccagt tattacacaa gtatttcatc aatattttgg ttaagaatac gagagtttgt
     9661 gacaaaagtc atgtcacaaa cttttttctt tgtcattttt tcgtaagaaa aagcaaaata
     9721 aaagtatata cattgattaa aagtatatac ttggatataa tgtacttact atagaatgag
     9781 aatggtatag agggtggcga aatatgaaaa aaatgaaaaa gtataaaatt agaaaatctg
     9841 gcaatagcga tgtaacaact atcccaccag aagtaaaaga attcatgggt gtgcagacag
     9901 gtgacgcaat cagttatgtt tttcaatctg atggttctgt acgaatgatc aaagcacaag
     9961 aagaacctga tattgattca ttagttgatt cgatcatgaa tcaatatgaa gacgcgttaa
    10021 aagatttggt tgatttatga ggtatctttc gactaaagaa attatcaaaa tcaacgcgaa
    10081 agttatttta cgtcactcgc caggcgaaat gatcggtgta aaagatgcaa atgcattaga
    10141 tatggccgtc aaacagcctt cacaagcagt attcaatcaa gaactctatc ctgaaatcta
    10201 tgaaaaagcg gcgattttag caattaattt agctaaaaaa catccttttc ataatggcaa
    10261 taaacgaact gctcttgttg ccatgttgtt gtttcttcaa ttgaataatt gtccagttgc
    10321 tttttctcgt caagaagctg ttgattttat cataatgatt accactagtt cattggattt
    10381 cgattcacta aagtccaaga taaccagtta tttacgacaa accgcaataa aatgaacgaa
    10441 ttaaaaactt tatttctcaa ttagatcagc atgtcattaa ggaatatgct gattttttta
    10501 tgtttaatca tacaaaatag ttttttcata aaaatatgga aaatatggat taattttgaa
    10561 ataattgatt taaaaggaat acaaaagagt gaatagtagg aaatagtggt ttagaactag
    10621 tgggctgatt ttttatatat tttagtttac ataatatata ttatacaaag tagatttaaa
    10681 aaatgataaa cctctctcga acggtttttt atcaaaaatc gtcatttttc catcaaaatc
    10741 tgcttatgca aaattataaa aaaattttgc agtttttctt actttttttg tcgtttaatt
    10801 gaatgataaa aaccagtttc tttattcagt taatcaaata tgaacgaatt agatatgaat
    10861 cattgtattt gccgttgcgg aaggattttt taattaacca cagataaaca ttgataacga
    10921 ttcgcttatt gtaatcaaca gattaaattt catatgttca tatgtacgga tacattttcg
    10981 gaccgattaa ttttaaccat tctatttatt tgcttaccta ttagatatca ataaaaaact
    11041 gcttaacagc tatttcagct gttaagcagt tttaggattt ttagttcata ttcattgttt
    11101 cttataatac agtgttcaat acttctctta aagcacttgt tgatttgctg aacattgctt
    11161 tttcttcttc gttgattgat aattcaacaa cttcacgaac accattttcg tcaacgattg
    11221 atggcacacc tgtaaagata tctttttcgt cgtattcacc agttaaataa gcagatacag
    11281 gcaatacagc ttgttcgtta ttcaagatag cttttacgat acgtgcagta ctcataccaa
    11341 taccatagta agttgctttt ttacgatcaa tgatctcata agcagcatta cggactttat
    11401 cagcaatcac atctaattca tcttgggcaa tacgatggtc tttttctaca atttcaaaca
    11461 ctggtttacc accgacagtt gtatgtgacc atgcagcaac ttctgaatca ccatgttcac
    11521 ctaagatata gccgtggacg ctgcgtgggt caacttttaa tttcaatgcg atttctttac
    11581 ggaaacgagt tgtatccaat gttgttccag taccgataac acgtgatgtt ggcagaccag
    11641 attcgttcca agcgatatat gtcaaaatat ctactgggtt tgaagcaaca acgataatac
    11701 cgtcgaatcc tgatcccatg atttctttta cgatttggcg catgattgac gcatttgttt
    11761 taactaaatc taaacgagat tgaccaggtt tttggttgat accagctgtg ataacaacga
    11821 tatcagcatc tttacattct tcatagccac ctgaccatac agccacattt tcatcgcccc
    11881 aagccatacc atctaaaagg tccaatgctt ccccttctgc tttttcttga ttcacatcga
    11941 tcaatactaa ttcattagag attccttggt tgatcattgc ataagcgata cttgttccaa
    12001 caaaacctgt accgacgatt actactttac gacttgtttt tttcatgaat aaacagctcc
    12061 ttttcataac tatttgttac tttcatgaaa agtatagtct tgtttattca ttttatcaac
    12121 atgttaatta taatagttgt tattataatt tttgatggaa acgaattcct gaatacgcat
    12181 aacagataaa tgacaaatgt ttacacctat atcccctgat aatacaacca aaagtttaga
    12241 actgaaaata aatccaaaaa aattcgctgc aacgatataa taagacagca atcgcaccta
    12301 aaacaatttt ccttcatatg ctttagtgaa agattttctt cttaatgttt atttctccat
    12361 tcattgggag tacatgttga atacttcttg aataatttga ataaagaagt cgtttgttta
    12421 tatccgatac gattagcgat ttcttccaac gaaaaactcg tttcttgaat cagttccaac
    12481 gcaaagtcga attttttctt tagaaccagt tcttgaaagg aagcatcaaa atacattttc
    12541 aatttattac taagatagac cggattgtag ccaaaatgag ctgctgtttc ttttaacgta
    12601 caagaagtaa aatgcttatc gatataatct aatactctaa gcatctcatt ttctgcgcat
    12661 ccatctgctg atgaaaagct ttgttgttct aataaatgag tcaattcgat cagtaatagt
    12721 gatgtataga gatttaacga acggatctta tgactgtatg tatcaaaata aatcaacagc
    12781 atattttcaa tcaaatgcgt caaacgactt gtttttccgc cgcgaaaatg aatgaattgt
    12841 gtatgttccc ctttttcttt tgatgcattt atcaaaaaag aagaaagtag attatttgtg
    12901 cttgccaaat gattcaatat ctctgtagat aaggtttctt cttttaataa gatgttgatt
    12961 aaaatatcct cttgccctgt gtattcgatt ctttgagtag cttctttatc aatgatcacc
    13021 acgtcacttt cttccatctc tatcctttct ccattaataa tttgtaaaca tgtaccgcta
    13081 tacatataat tgatttcaac aaaatcatgt gtatgctcgg gaacttccgc atatcgacgg
    13141 tgtttactga tatgaatatt tccctgttga aatagatccc ctcggtggat ttttggcggt
    13201 gtctgaagat ggtaagctaa gtttaaatca ttgatattca ttccttgttc acgctgcaga
    13261 gtttcgattg attcttcgtt acgcaaaaaa atgtctaatt cagctagttc caattgactc
    13321 cctccttttt gtaagcggtt tctttcgctt attagttcac gctgtactgc tattatatgc
    13381 aaagctattt ttggtttcat aaagactttc tatggttggg acatgaactt cctgtgattc
    13441 cgctattgag agaataacca cttcatacta tatttttgat aagcgcttac aaaaatgaaa
    13501 ggaacatgct tatgaataaa aagatgatga aattttctct gctgtcagtc tctcttattt
    13561 tgacttctgc tggtgcagtc acgtctgcaa ttcccagtat gtcagctact tatgccacgc
    13621 gttctttatc tgctgttgaa ttattaacga ctgctccctc ttttatggtc actatttttg
    13681 ttttgattag tagttttatt gctaggaaaa tcggacaaaa acaaactgtg atcatcggat
    13741 tagtgattgc atcgatttgt ggtatcctcc ccctcttctc acaaagttac agtattgtct
    13801 tagcttcaag agctggacta ggtattggct ttggattgat caattctttg gcagtcagca
    13861 tgattgctgc cttttatcac ggagatgaac gagcctctat gattggtttt caaagtgcat
    13921 ttcaaggatt tggtgcagct ttaatgacat ttgttgcagg acagctagta cagttcggtt
    13981 ggcaatatac ctttttagtc tacgccatca gcttacctat tcttgtcttg tttgttttgt
    14041 ttgttcctac acctgaaaca actgaacttc aatcgcatgg cacagcccca acaagacaag
    14101 taatcaaaac gaatcctaaa atgattagtt atggtatttt tctcttgctg gtcatcgtgg
    14161 tatataatgc tgtatcgatt aaattagcca cagtcctgac gacttattct ctaggaaacg
    14221 aaactaatgc agcgaatatc ttaacaatca tgcaattggc aagtatggct gccggagttt
    14281 gttttggctg gcttcagaca aaagcacatc gctatatgct tacactttct ttactactga
    14341 tgggaatcgg ctttgtattg attgccactg tgataaacct gtatgtgatt gggtttggtg
    14401 cgatcctaac aggaatttct ttttcgttat tcattcctta cttattcaac caagtaagta
    14461 tccaagcgcc caagtacgcg gagagtttca atacttcaat cttattggtt ggcgctaatt
    14521 taggtacttt cattgcacca tatggtttgc tctttctctc ttttgcttct cttgggagta
    14581 aaacacttgc tgttttcgtc aatggcagta tcttgctgtt gattagcgcg cttattagcc
    14641 ttctagtagt acacaggacg aatagaaaga cagtgataag agtagatgaa gaaataaaag
    14701 aacaattgac aacaaaataa atttgatgga ggtcgtgtaa aatgacaaat gaaaaacata
    14761 aagatagatg gctttggtat cctggagact ttgagatccg ccatggactg ctacaaaatt
    14821 tccaacggga agaacgaggt tttgactggc cagcgtactg gtacatggat gattgccatc
    14881 ggaacgtcaa gtttaagaga tattactttc ttgatcaacc ttccatgttt aaagtgacga
    14941 tccaaggagt tgggtatgta gaaattaatg gacaaaaaca tccatgtgga aaatggctga
    15001 cttgtccagc tggtaaagca aaaattcgta tctttgtagg acatacatca gggctaccag
    15061 cgatgtttat cgagggagac gaagtaaaat cagatattgg ctggacagca agtaatttta
    15121 ttgaagaata tccagctggc tggagtccgc tttatgtcga tatcgcaaaa gatccaaatc
    15181 aaatctatta tcaaaaagaa tgcgtccatc cagtcactga aacggagatt ggcggaggaa
    15241 tcttattcga ttttgggcga gcagtgaatg gctgtgtaga actaatatct ctggatgacc
    15301 atatcgaatc tatcactcta tgttatggag agtccgatgt agaagctatg gatatcgatt
    15361 attgctacta taagcaaata ggaatgacaa gaaaaatgaa agctcgtaaa cgcgcttttc
    15421 gctatttgtt tataccagag gtttctactg gaatggttca acttcaagtt tttcatgaat
    15481 ttttatctct ttcgaaacaa gctgcttttt caagcgattc ttctttactg aatcagatct
    15541 ggtcagtatc agaagaagcc ttcaagttat gtagtgattt gttttttatc gacggtatca
    15601 aacgagatcg ctggatttgg tctggagatg cgtatcaatc attcatgatc aatcaatatc
    15661 ttttttttga cgaggaaatc aataaacgaa cgatattagc attaagagga caaaatgaaa
    15721 tcaagcagca tatgaatact atcgttgact attcgatctt gtggttgatt ggtatcgaaa
    15781 accactatat gatgacgaaa gactatgaat ttttacgcat cgtctaccct aagatgcaat
    15841 cattaatgag atacttgatg gagcaaacga atgaattagg gtttatttat gggagagcaa
    15901 aagattggat atttattgat tggtctgaaa tggataaaga aggaacgctt gctgcagaac
    15961 aagtcttatt actgaaagcc tatcattcca tgatcacttg cggagatatc ttagctgaaa
    16021 catatggaga gaacgaaaat tatcatactc atctctatca agaaaaatat caactattga
    16081 aacaaaacct atttgactac ttttgggatg aagaacttgg cgcttttatc gattgctatg
    16141 aatctgggag aagaaatgtg acgcgtcatg cgaatatttt cgctgtttta ttcgattttg
    16201 ctaacaaaga ccaacagcaa tcgatcttaa agaatgtctt attgaatgac actatcacac
    16261 agattactac tccatatttc aaattctatg aacaagatgc tttatgcaaa ctcggacaga
    16321 cgaatatcgt ctaccaaacg attcttgatt attggggagg gatgttatct catgatgcgg
    16381 taactttctg ggaagaatac gaccctactc aaacaggaaa tgaaaagtac agtatgtatg
    16441 gagatcctta tggaaaaagc ttatgccatg catggggagc aagcccaatc tatcttttag
    16501 gacgctattt tatcggtttg tatccaacaa agccaggtta tgaagaattt atgatacaac
    16561 ctaatctaga ttcatttgaa acactgaatt gtacgctacc tatcaaagat ggaaagattt
    16621 cgcttgaaaa aacaaaagat aagatcgtga ttacttctga tagaacaggc ggaacagtga
    16681 aaatgaatgg taaaagttat cctcttctag caaaacagcc acttgtctta acaagctatt
    16741 caaaaataaa tgcataaaac aaaaaactgc ttgcgacata tcagaagact ttaaatcttc
    16801 ttctgatatt gtccaagcaa tttttatttt gaagtttgct taattctgtt ctttagaaac
    16861 aatgtttgtt ctttttccgg caaaaagaaa gctagataat acgacaagta aaaagaaagc
    16921 gatgattcca actgtcaagg ctatttgacc gtattctcct agtttcccaa gtacaagtcc
    16981 tggtactaga taatcagtat cggcaaatgt agaagaagcg attttaagat ctcctaatac
    17041 tggaaggata aataatggca gccaactaat caataagcta ttgaaagcag aacctaatac
    17101 cgcccctctt ctaccgccag tcgagttgcc gaagacacca gaagcagctc cgcagaagaa
    17161 atgtcctact accccaggaa tgataactgt agtttgcaag cctatcatag caaacatgga
    17221 tagtgttcct acaaagaagc taacaaaaaa gccaattaat acagcattag gtgcatatgg
    17281 aaaaacgata ggaacatcta atgctggttt agaatcgggt acgagttttt tagcaatccc
    17341 ttggaatgct ggaacgattt ctgccaacac cattcgaacc ccttgaagga cgataacaaa
    17401 cccagctgtg aatgttccag cttggatcag tgcaaagatt acagcgttgt ctccattgct
    17461 tagttctctt tcaacaaatc caggaccagc taacaaagca agtgcgacat atacgatcga
    17521 catcaagagc atgatcgata cagtagaatc tcgcaaaaag ctgaaacttt taggaatctt
    17581 tatgtcctct gtagaacggt ctttgtttcc aaaaaacttt ccgatccatc cactagaagc
    17641 ataaccgata tttccggtat gccctaacgc aacttgattg tttccagtga tgttcttcat
    17701 aaacggttga caaagagcag gcgtaatagt taatagtgtt ccttcgaaga ccccgcctaa
    17761 taagatcatc cacaaatttg cagtaaaccc cgcgcttact aaaatgactg ctgttagaca
    17821 agaaacataa agcattgctt gacctgtaag aaaaatgaat ttatatcttg tgaatctagc
    17881 aagtaaaata ttcacgatca tccctactag catgatcaaa gcagtaggtg taccgtattg
    17941 ttgcaaagca atcgccacta ctgcttcatt gctaggaact actccttgag tatgcagagc
    18001 tgtttggaac atcgaagcaa aaggggttag tgaattactg attaaaccag caccgccgat
    18061 cagtactagg aatccgacaa atgttttgat agttccttgg atcacttctg aaaatttctt
    18121 cttctgaaga acgagaccaa gcagtgcaat caaagaaacg aggatggagg gctgactgac
    18181 gattgacaca aacaaattca acaatttatc cattgatagt tcctcccttg aatcattttt
    18241 attcttttga caagatcttc gttacttttt cttttacttc ttcgctgtca atgatcgatt
    18301 gcaaaggtac gagcttttca tcaggtatag aagttagcgt atctttcaaa gaatgctcaa
    18361 tgaagaaata atcagccata tcgctagata cacttccaac atccgtatga cttacttcaa
    18421 actcgtccac atctgctcca agatctgcaa gtgcttgttt gatgttcatc tctaccataa
    18481 aacttgttcc taatccactt tgacatactg caaaaatttt catatcattc gtctcctttt
    18541 cttatgatcg ctaatatttc ttcttttgtt gatgcgtgta ataaatcttg aagattttgt
    18601 ttattagaaa gtagctttgt taaatttgcc aaagcccgaa gatgtgcctc attatcgata
    18661 gcagctaaac agatgaacaa actaatggga tgggctggat tatcaagcag atccacaggt
    18721 tgttgaagtt tcagcaaaga catccctact tcgtttacgc catcttctgg acgagcatga
    18781 ggtaatgcga tgtgatcgcc aatatggata aacgcaccat actgctccac gcgctcgatc
    18841 atagctttga tataactttc ttctatttta ttttctgata atagcggctg tgcggcaaat
    18901 gtgattgctt cttgccagtt ttttggttga tccgataatt ggatcatttc ttctgttaat
    18961 aattcagata gcataggacg ttgatcctcc ttcttttcta aaagtttgtt cattttacga
    19021 tttaatactt gatagagctt ttcttcgtct acgccttctt ttaattcgat ataaggcagt
    19081 agcgccgaca acaattcttg ggcagaaggc attgaaaatc ctggtatcag ccaatctctt
    19141 tgtacttgat tgatcagctg atttttttcc aagtcagtca tgattggatg cagaacatag
    19201 agagactttt tcttatcagt aagtgtgaga ggtacagtag aaaaaataat atcgtaagaa
    19261 gtttcgtcaa cctcgtgtaa gcggtcagct gaattagtct ctgtaaaaaa gatcatcggg
    19321 aataattgct gaagttcact ttttaagatc aatgaagagc taatgccact tggacagacg
    19381 atcacggctc ttatttttct atttctttct tctgcgtccg cttttctgat ctctccgcca
    19441 aatagtatag tgaaaaaacc aatctcttct tcagggatgc tcttccctat tcgtctttct
    19501 aacggaagta atgcttttct tgtcatttcg tagatggaag catattgatg cttaatttga
    19561 tcgatcatca cattaggtaa ataaaaagaa taggaaatac gaaaataggc agggaccaag
    19621 tgataaaaga cattcatcaa taattcacga aacgaagcaa attctacggc catcaggaat
    19681 tccatgcgat ggatgacttc tgaagaacat tccagcaaaa aatcaagtgc aggctcctgg
    19741 acatctcctt caacgatcga tgctaagcaa agagagaaaa atataatctc cgaattttga
    19801 tgttcggaat agccaaggcc agtcaatact tgtcgactaa tgtcagtgac tgcaagagaa
    19861 gccaacagtt cagcatcttt taccagttcc atggatgttt ttccaattcg aatggttgtc
    19921 aaactcaaat aataagctaa ttcatccatt cgatttggtg cgaatcgaag atctgatagt
    19981 gaaatcgttt tatctagcaa atctctaact ttggcgtaat aatcaatgga aagggttgcg
    20041 gttaaatacg tgagcccaaa tcttccagca agtgactgca tcaaacgagc agtgcgattt
    20101 tttgcttctc ttcttaatat tgcttctgac cctagcagcc taaaaccagt tttcctagta
    20161 tacgacagct gacaatcttc cacttctaat tcatttctta tctttttgat atctgacagg
    20221 actgtccctt tagaaacctg aagaaaatct tgaaaatgaa aaacagaaac agacgttgca
    20281 gtcgaataaa ccatcaaata aagaagatct cttcgctctt gttcggtata cacagcttca
    20341 aatcgagtaa tatccaaaaa tttttctgcc cagtcgattg ctcggaattt ctttatacgg
    20401 atacgggtat catccacata ttcggcaaaa ggagttaatt gtttgatcgc ctcgcttgta
    20461 tttacttcga tgatctctgc tgctttttct agactgattt ctcttggtgt tttcaggaga
    20521 taactaattt tgtagttcac agcgctgttc acctcctact tatattctag tatggtagcg
    20581 cttttaaatc gaggggtgtt tggtacaact tacagttgga ttttttttac gactgtaccg
    20641 aacgatttct atcgaatgga tacagaaaaa aagcaggtga ccaaatgtct cctgctttta
    20701 tgaattgatt tcgtccgatc aatgatgatc atgtttattt tttgaggtca gttcttcaaa
    20761 tttttctttg acatcttcaa ccgctttttc gatatctttt tcaaagtgat tgggctcatt
    20821 aggctttgtt tcctcttcta cagaatttga accagataaa gctgtttctt tattttctgt
    20881 ttcaccagag tttgtgccag ctaatgattc ttctttgtct tctgtttcac cagaattagt
    20941 tcctgctaaa gccacttctt cttctgtttt aggggccatt gaacctctta atcgtttgtg
    21001 tttttcaccg tcataatttg tcatgttggt tcctcctagt agttctatac tttttcatcg
    21061 tacaataaga cagtttatgc gtcaaaaaac aaacccgatt cttacaaata tgtcatattt
    21121 ttccttctga ttcttgaatg cttttgattc cttcttccaa aattttcatt tgtaagattg
    21181 tttcttcatc tttgatgact ttttctgcgc cattaactaa tgtctcgtaa atcccttcgt
    21241 agacacggct gtaatcacca acctcggaaa ttactttttc ttcatgataa ctcccttgtt
    21301 catctatata ggtcaataca ccataatgtt cgggcaaatc gataccaaag tcttcatgat
    21361 caggcatgta aaacattttc agatgttctt cttgtcgatc ttttgtttgt ttcacgaaca
    21421 tccctttttt ccgtaaacga cgaaacttgg acgttctttg atgcggaaat aactggattt
    21481 tatcgaaatt ttcatatttc catagaaaaa atccagatcg aagtaatcat tcattcgtcc
    21541 tttccctaaa agttgacgta catcatagct gatatcatct ggttcgccga aataagaaag
    21601 aacttgatct actgtatgac aagcatgtcc atataaatag ctgttcgcag tagaaaattc
    21661 atgcgtattt tctggtactt ccggtctgaa ataatcataa tgcatttcta cttctaaaat
    21721 atcccctaat tttccgcttt cgattacttt ttggactgtc aagaagtcag aatcgaaccg
    21781 tctgttttgg taacattgga taaatagacc tttttctttt gctaatgcaa ataactcttc
    21841 tgcttccttt gacgtttctg caaaaggttt ctctactagt acattcttac catgttcgag
    21901 tgccattttt ccatattcat aatgaaattg actaggtgta gtgatgacaa ctaattggat
    21961 ctcaggatca tcccaaagat cagacagctg atcagtatat tcgatgtctt cgaatgtttt
    22021 ccacactggt tcagatgggg aaaaaatttt tttgatattg attttgttcg taagttttct
    22081 tgaaaaaggc aaatgatagc gatttgtact ctttccattg ccaagataag cgattgtaag
    22141 catgagtggt gcctcctttt attgatgttt tcagtatatc ctagaaaagc gcagaaagta
    22201 tttataatag ctattctggt aaaaaagttc agaaaaacac ttgttatcat tcggtttggt
    22261 gaaattaatg ttcaaagtaa ggataaaaat caaaaagata gtagcggaac caagtgttta
    22321 tcagtaagat agaatttgga ggtcagatca tgcttattga agaaaaacta acaaaacaag
    22381 agttgtttac cacgacagag aaacggattg tcgattacat ccgtaggaat atcgaagctg
    22441 cagtctacat gacgattgaa gaattagcaa aagctacgta tacttcccat tcagctatca
    22501 ttcgtttatg caaaaaaatg ggattcagcg gatttaaaga attccgtttc gagctggggc
    22561 gggaagttca tcaattgatt gctcagttca atcaaacgat tgatcctaat tttccttttt
    22621 caagtgaaga tagcactcag caaattgcaa agaaaatggc ggatttatcg atccagtcaa
    22681 taaaaaaagc acaattgcag attgaacatg aagatttaga tcaaatcggt aaagtattga
    22741 acaaggcaca gcgaatcttt ctttttgcaa aaggtgattc tcaaatcacg gcaaggaaat
    22801 tccagaataa aatggtcaag ttgaataagt ttttgatcat ggctgaagaa tacagtgatt
    22861 cttcttggaa tgcagccaat ttgactagcg aggattgcgc catttttatt agctacagcg
    22921 gtcgcatcca tcattatgaa cgaataatga cctatttgaa gcatgtagag gcccctacct
    22981 tgctgattac cggaaatcag cattcagaaa tggccaaaca ggctgatatg tgtcttgtta
    23041 tatcgcagga ggaatatgat tttgctaaag tagcgacttt ctcctctcaa attgccttcg
    23101 attacgtatt aaatacgtta ttctcagtga tatattctca aaattttgaa gagaatatcc
    23161 gcaacttgaa aaacaaacaa gaattgatgc aaaaaggcct tcttaaagaa tatcggaaaa
    23221 cttaagaaaa gatcctcatt tagtaataag aaagatagtg tttgataggc tctctttgat
    23281 atcatcataa aaacaggctg aagttttctt tttcaaacct cagcctgttt gtttacggaa
    23341 cgattcgaat agatatatta tagaaatgag gaatagctaa cttctgtttc ttattttgaa
    23401 cgattgacga aaaagatata taagaaggag gaaaatcagt atacatgcag ctaacaatcc
    23461 atacaggaaa aatcgtttgt tctcggatac tttctgtact tctttttgaa cttcttttgc
    23521 atgataagga acccggtgcc ctctgacaag taagcgatga ctgttgacca tataaggtgt
    23581 acaagttagg agtgtcacga aatcctgccc tttttcgatt ctcagatctt ttgtatcagt
    23641 cggttctacc gtcttgatct gatcgacttg ataagcgagt gtccgtccat tgatttcgat
    23701 atagaaagaa tcacctaaag tcagtttcgg taagtctgtg aacaactttg cttgaggcag
    23761 tcctcgatgg ctggaaataa cggcatgtgt attttctccc cccgtaggat aagacgttcc
    23821 ttccaataat gaggcacctt tttctagcag cacagtattc gtttcatcaa aaattggcaa
    23881 atggacattg atctcaggga tcgtcaaaat accgatcgta tgtttctcaa aataggttct
    23941 atcctttttc gcaggttctt ttttcttagt aaagggatct gcacctggat ttccaccttc
    24001 ttttgctaat tgctggtttt tctttgtcat gttttcttgg attttagcca tgacttcttc
    24061 attttctttg accgcttgtt gctgataatg agagatgatc tgctgatcca gataattatt
    24121 cagcgcgtcg ctaacaaatg gataagctag tatccctatt cctgagagaa gcaagaaaag
    24181 catcagcaga tctagaagtt tccttttctt tggtttcatt tgtgttctcc ttgtgatgac
    24241 tgtttgataa taaaagaaaa aggagcattt gcgtaatccg ctgctccttt ttccaattct
    24301 tgcaaaaaga ctaaatctga ctgtgcttgc gtctagcaaa gtacagtcca gcaatcagta
    24361 gaaggactac tcctgcaccg atatacacat agattccctt accgcctgtt gaaggaagtg
    24421 tacctttgtg tttatttggt attttttcag gagaaatcaa ctgtcctgct gttacataag
    24481 attgttcatc gatagtaaat gctacacggt ttgttaatgg aacatatttt tctggcgctt
    24541 tcgtttcttc cagatagtac gtgccatatt ttagacctgt cacatcgatt aaaccgttac
    24601 ttgtggttgt aaaaaccgtt gctgattctt tcgccgatac ccagctgacg gcttttgtgg
    24661 atgggtcgat cgataaatat ttcgctgtgt cactatcttg atcacgaacg acgaattctg
    24721 ctccagcaag tgtttggtct gatgtaacgt caccatctac tttaacaaat cgtttgcccc
    24781 cagtaacgac atcgactgac ggtggtgttt gatcatttgt atgcccgtta tcgacatttg
    24841 cttggttaga aaatcctttg gttggatctg ctttttcgtt caaatgcata tagtaaacga
    24901 atttcaatgt accgccagga gttaatgaag gaatataatt cggatcaact gaaaccgtga
    24961 atccgtctgt ttgctcagtg acagaataat ttactgggtc gatttcttta tttccatcat
    25021 ataaggcata agcatacgtt cctgaagaat cattatcaaa tgttaaagca gcgtcatgag
    25081 tatcgataag tttgaatgtt gtgtacttgt tttgcgttcc ttctttatca gcgataccta
    25141 atgggatatt gacagaaatc tcatattgaa ttttttcacc gattgcgaca tcttttccat
    25201 tcaattgagg tgttgtttta tcaactttag acgtatcatt tttgatggtc ttttctactg
    25261 gtgtttggct atttgccagg atctcaaaag gcgtgattgt ttgcttttca atcatttccg
    25321 cattatcagg agcttttact tcttctaaat tatattttcc aacttctaaa tgattaacga
    25381 tcaactggcc tttttcaata gatgcctcgg caaagtcatt gttgccgatg tcataagaat
    25441 gaccagtaat gaaatgtttg gctttggttt gatcagttgt ccaagtgtac aatccatctg
    25501 tgacactttg gatgtatttt ttgacgcttg gtgttccttc ttctttagaa ataataaatt
    25561 ctgctccatt tagtgcttcg ttttcggcag taccgatttt tgtaactttc aacgttccat
    25621 cattaccgac tgtattttta gggtagagat ggatagtatc tagttcttct gtcccgtatt
    25681 tataagagcc atctgcttgt ttgatcatct catatacagg gaaagctaaa accatgtttg
    25741 cggcagctga cactccgtct tttggttctt ctttgatcgt gtagactgca tctttcccat
    25801 tttgtttttt aggtaaagat aaagtgacat ttccatcagc atctgtcgtt cctgaagcaa
    25861 ctggtgtacc aggagtcaaa gactggactg cttgttttgc tgcatccacg gacgctcctt
    25921 tatctcgttg cgcataaaat tcttgagtga cgttataaac tgaaaatgaa atatcggcta
    25981 atccttggta ttgatcgaat tcgctcattt ctttcccgct gttttggatt aaaggatcgg
    26041 gtaaatcagt cattttcttt ttatgaagga tgacttgagc tgctgtctcc tctgcaaaca
    26101 ctttttttgc gccgaagctg tttgtgagta atggtaaaat aaggaaaagg actcctaaca
    26161 taacgtttat ttttttatga tttttcattt tttcactcct gttctttttt tgataaacaa
    26221 ccagattgca aagcttgcga ataccatacc aacaacgcct aaaagtgtat ttttcgtttc
    26281 gtttgttttt ggaagaaatg gacggctatt ttctttttta ttgactactt tcaatatact
    26341 gtccgcctct ttatcctcag aaagaaaagt tgaaatggta aacggaattt ctgtttcact
    26401 taaaatataa ccagaaggtg cttcgatctc ttttaatcga taacttcctg ttttcaaccc
    26461 ggaaattgaa aaagcgccat ttttatcgga aatcaggtga agcgcatctg attcgttctt
    26521 tgtccacttg tatccgttgg ctgtttgctg gaggtaattt cctgctttgt ttttaataag
    26581 gaatactgcg ccagctaatc gtttatctgg tttatttgtc tcgattttga caaattgctt
    26641 actccctgta tatacagaga ctttctttgt actgacacca aaaccaaaat ccagtgttcc
    26701 gttgttgttg atttccttgt tcgcctgtgc tgtactgctt agctgcatct gataagaaat
    26761 ggtcagtttt tttccagcat atttttccaa cgaagggatc gaaaataaaa catcaaatcc
    26821 gtgaggtttc ttgtgtatga caaagccttc tgtcagcttt tctccattcg atgaaatcgt
    26881 taaactatta ggtaaaaacg ttaatgcttc atccgcacta tctgacaatt cgaacttttg
    26941 atagtcaagg atatttacag gaattgtcgt atgcaaggaa taagtgattt tttcaccaat
    27001 cgtaaaatca tttctaggct cttctaatac cttctcaaaa ggtggatcag ggtagtcgtt
    27061 ttcttcattt ttaggataca aatggatagt tgaaagtttt tgattgtttt gtccatgtac
    27121 aggaagaaca actaccatat tctctgcctt ttctttgacg acttctggta ctttggattc
    27181 aatgaaaaga tacgctttat ctcttttttc ttgatcttta gcggccagag aaaaagaagc
    27241 gataccatct tcgttgttaa gagttgtagt tgttgcttct gcggtaaaca taccggaaga
    27301 cgcaccgttt tttgcgatct ctgcttgtgc ttcttctacc gttttgccct tttcccgtag
    27361 atggtaaaaa gaatctgtga catcataaac ttggaatgtg acaccattta atcctcgata
    27421 cgtttgtaat aaagcttttt cttgtccgtc atttggatga tttttcggca gttgcccgtt
    27481 tgggaaaagc aatttgtgta aagtaatctg aaccatttct gtttctgttt ctgttgctac
    27541 ctgagtaaaa gctggtttaa atagtaacaa gaagagacac atactaagcc aaccaagttt
    27601 tttcatattt agctgccccc tctttctttt ttcaaaaaaa gataccaaat agaaaacgca
    27661 caaccaatca tccctactag atagattcct aaacggccaa ttcctcccgt ttcaggtaat
    27721 ggtacttttg cctgattcgt gatgtctaaa gaaatctggt tgtttttggc tcctggtgac
    27781 agaacagatt catgatcttg tccatccact tgaattgacc catcttcgtg tataactata
    27841 gtaactggct cttttagacc ttggtatcct tctggtgtaa aagtttcggt cagcgtataa
    27901 gttccaggtt ttaaattttc gaatagaaag gtatctgttt cttgtccatc ttttggcgat
    27961 tctaagtcca tttctggtcc ctgcagtctg aattttgctc cttttaatgt ctgtccgttg
    28021 tcttcttttt tgtgtaccgt tagatcaaac gcttttagtc gattttgatg agtgagcgtc
    28081 catacattat ttgtcatctc ggtatttttt cccgtgtaaa tgatttttcc atatttatcg
    28141 atttggaatt cataatttcc cggcgaagta tcatatccgg caggaccagc tgtttcaacg
    28201 actcgatatt taccaggtgt gagtgaatca aaactggcaa gacctttttc attcgttgtt
    28261 tggctgtcaa ttggctgata agtaccattt gcttcttttt tctgtaggga aaatgctgct
    28321 cctttaagat ttatctcttt gtccgtccct tgcatcgcat acttacgtac tgctacagga
    28381 acttcaacaa aaggattttc aatagtcaac tggatcgtat catcggaagt agtgactgtt
    28441 tttccatcaa tggttaccgt accatcagaa gcgatcttga tttcccaagt agtctttttg
    28501 cttaatccat gcccttctgg agcttttgtt tctgtcagcg tataggtcat ttctttttgc
    28561 aatttgacat tttctggaag agaataggtt ccgtcgccat gatctgttag taaagtatca
    28621 atagaatctc ctgttaattt gaaaacagcg ccaataagat ccttttcacc tgtagaggaa
    28681 tttttcgtta ttttcaagtt taacggtgtg aattgtttag tatttttcca tgtcattgca
    28741 tctatttgtt gagaatcgta tcctggtaca ggtaattctt tgattgtttg gtaactgaat
    28801 gcttgacctt gattattgta ttgaggtagt gataatatct cttgataact ttctccgcta
    28861 tttgcagata atttgtcaat gtctgcacgt tcccacgtat ttgttgtatc tttagctggt
    28921 ttaatgattc gaatatatcc gtttttccaa gctgcagcat ttgtcgtatg ttcccgttga
    28981 atctcaaaag taacttgatc tggacgatca gctagattgt tgtcaaattc ttcccataac
    29041 tttttgatgt gaagactgac tccgggagct ttagcagatg gtataccgaa ttcagctaat
    29101 tcattggtat caatgtttgg ctggaaagtt gtcctgccgt tcatttgata ccagaaattt
    29161 ggatggaagt cctcattttc tgtttggatt ctcacttggt aatggatttg gatttcttgg
    29221 tcttttccta aatagatctg attgctcttg atggtatttc cttctatgga aatagatgga
    29281 gtgaccgttg taggacttgt ccccacactc ttgactgaaa gtgtaccagg ctgataaatg
    29341 aatggttctg cgattggatc atttatttgt ccattgctta cagttgctga gatctgtaca
    29401 gcttttttgg ctaggtattc agagatatct gttgcatgat cagctgattc atagtaaaga
    29461 tcgccttttt catctgatga aaccatttgt cgcatacgag actctacttc tgcttttgag
    29521 agaccagctg ccggatcgct ttgaagttgg atgccaagac catgtatttc gattcctcgt
    29581 tctttgagtg ccatcgcttc tccgatggtt gcgataaacg tactgtcgat tcttctggat
    29641 agattgtttt ggtcaggtgc atcatagatt cttgagatta gagaagtatt tcccggccga
    29701 tcttgcgtat tagaaaactg agttccgtaa taattgctgc ttgattgtgc gtgtacccgc
    29761 tgtactttat aggaaaatgt tggtacacca tccgtcagca aaacgatcac ttttttatgt
    29821 ccatttggaa cggatagcat gcttcctgca tctcttagtg ctttttgtgt aaaagtacca
    29881 ccatttgtcc gtgaaggtgt aatggatttt acttgatttt tcactgaatc aaatgaaccc
    29941 atctgtactg caccgttact gtagctatat ccttcgcttg agtagccgac atatcccata
    30001 ttgattttgt ctgtgatacc gctatctgct aaagtatcga caaaacgatc gacaccaatc
    30061 tttacttcac cgatccgatt attgtcgttc atacttcctg accagtctac gaccaatacg
    30121 agatcaagag gcgtgatatc tttttgtaca tttccacgag cattcaaata aacatcaaac
    30181 aatccgggtg tacttgtttc ctttgcatac tttcgtatcg catagtctgc ttgattaccg
    30241 gttcctccat attcgatata cgaatgggtc cgatcattag gatctccatt ccaagaattt
    30301 ataccatccc attgatttgt tccgttttta ttgccttgat gatcaagaac atttgtattt
    30361 cctgtaggtt gccaactggc tttaggataa gtgccctgat catctgttgt atattctgta
    30421 ggaatcgttt gattagatgg cacactcaca gctggcaagg ataatgtagg caatgtaaat
    30481 gggctgacag aattttcgtt ttcttttgat gattcttctt ctatttcgtc tggctttggt
    30541 actgacacat ctgtatcttt cttattttct gtctcatcaa taatgtcata ttctttatta
    30601 tcgacgatca gcttgtttgc ctggctgtgg taaagtgctg gatcgattgg aaaactcaga
    30661 tcgatagttt gtttagtgtt tgatgagatt tccaacgtaa ttttcccgct atttacctga
    30721 taagcatagc catctccttc ttttctttcc acatcactta agtaattttc gactagacca
    30781 atttcttttt ctatcttttc agcactggtg ttattcgcat ttagcttgat gttcagtgct
    30841 ttttttccag actgatccga aatgacttca gctgaaattg tttctaaaac tgttggatca
    30901 tctgtagtgt ctgctattgc agataatggc acaaagtttg ataaactcaa tattatcagc
    30961 atgaaaataa ctttcagttt cttccctgtg gtcgtcattt ttcccctcct ttttcttttt
    31021 ttctgttttg acgtgaatag tgaaaattat taaaataaac aggcgttaca taattttatt
    31081 tattttaata tgataattat tatacgaagg gcgctaaagg gaatcacacc aattttcata
    31141 ccaattggtt tcatttatga agttgattcc ttcgattaat gagcgtttca ttgaaagaaa
    31201 agggttgagg gagaaaaaca tatgatcagg ttgttggaat taaactatag aaagatggaa
    31261 aaaatcattc gaattctgtc catttctgac aagtggatga ctaaaaaaga acttgccaaa
    31321 cgaattggta gttcagaatc tacatttgta aggtatatcg aagagatcaa aatccgctgg
    31381 ggaacggatg taacgattca atcttcacaa aaattggggt atcgtcttga acatttgaat
    31441 gtaccagctt atttaaatgt tctgatggaa atgtcgcaaa gttctacaaa cagtcgttta
    31501 ttaaatgaga ttattgtcaa tccgggtaaa acgattgagt attattgtga aaaaatttcc
    31561 atcagccggt cttcttttac acgtaagttg aaacaatgca atcaaatttt agaaagctat
    31621 ttattaaaag tgatcgttga ccaaggtttt cagttaacta gccttaaaag tgagctccag
    31681 ttgcgtatct ttgttacctt tttcttttta agttactacg gaagacgcac gttgccattt
    31741 ccaatcgaaa aaaagaagat caaagaaatt atggtcaaga ataattgtca gatgaatttg
    31801 tttcaggaag aaagcccata tgagcaatct ttctttatta tgtattttgt tgtgcatctc
    31861 atgagagaat cccaaggaac tccatttgaa tggaaagctg gagactctta tgtacagttg
    31921 ataaatatcg ataaaaaaga cttcttaatc ttgaaaaatc tcttaggaaa attgaagtac
    31981 agcagctata taaaagtagt gaactatttt gtcaatacga ttttttcaga attttcggag
    32041 aaagaaaaaa atgaaatcag tgagcagata cgaaaaaata tgtcctactg ttcgttttca
    32101 tccgctgatt gcaaagaaaa aaacgaagaa tatgttgttc aattattaac gcaaatttat
    32161 tttttctccc gtattttccc atacgatacg actcatttga cgatccgtgc aacttacttt
    32221 gcacagcaga tgcaacaccg ccagatacgt ctatatgctg gatttcgtgc agaacttcaa
    32281 ttttattcca ctctactgaa tcagaatctg atttattatt tatctagcta tatcttttgg
    32341 atgcttatcg gtaatcctga aattcaccat tatacttctg ataaaaaaat actgattatc
    32401 agcgacttaa gtcttcgaca tagtcaatat attgaagaat atatcagtga tattcttgct
    32461 gtgcataaaa ttcactctga gacaactgct attactgaag atcagctgtc gaaatacaat
    32521 cttctcgagt atgatctgat cgttacgaat caacccattt tgaatgccca tgttcctcat
    32581 atattgattg atgatagtgt gtcattcgca aatgaagaag aactcatccg cttattcgag
    32641 ttatgaataa tcaaaaaaca gctatgtata aaccaccctg ataaaa
//
LOCUS       DADLIO010000025        32497 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.025, whole genome shotgun sequence.
ACCESSION   DADLIO010000025 DADLIO010000000
VERSION     DADLIO010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32497
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.025"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(<1..563)
                     /locus_tag="JOX41_001334"
     CDS             complement(<1..563)
                     /locus_tag="JOX41_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HAY6449089.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
     gene            complement(750..1400)
                     /locus_tag="JOX41_001335"
     CDS             complement(750..1400)
                     /locus_tag="JOX41_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449090.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            complement(1943..2878)
                     /gene="whiA"
                     /locus_tag="JOX41_001336"
     CDS             complement(1943..2878)
                     /gene="whiA"
                     /locus_tag="JOX41_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HAY6449091.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(2912..3910)
                     /locus_tag="JOX41_001337"
     CDS             complement(2912..3910)
                     /locus_tag="JOX41_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HAY6449092.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(3907..4791)
                     /gene="rapZ"
                     /locus_tag="JOX41_001338"
     CDS             complement(3907..4791)
                     /gene="rapZ"
                     /locus_tag="JOX41_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HAY6449093.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(4926..5657)
                     /locus_tag="JOX41_001339"
     CDS             complement(4926..5657)
                     /locus_tag="JOX41_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HAY6449094.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            complement(5661..6926)
                     /locus_tag="JOX41_001340"
     CDS             complement(5661..6926)
                     /locus_tag="JOX41_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HAY6449095.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(7189..10005)
                     /gene="uvrA"
                     /locus_tag="JOX41_001341"
     CDS             complement(7189..10005)
                     /gene="uvrA"
                     /locus_tag="JOX41_001341"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HAY6449096.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(10015..12009)
                     /gene="uvrB"
                     /locus_tag="JOX41_001342"
     CDS             complement(10015..12009)
                     /gene="uvrB"
                     /locus_tag="JOX41_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HAY6449097.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKEELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            12268..13770
                     /locus_tag="JOX41_001343"
     CDS             12268..13770
                     /locus_tag="JOX41_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAY6449098.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            13772..14509
                     /locus_tag="JOX41_001344"
     CDS             13772..14509
                     /locus_tag="JOX41_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAY6449099.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            14515..14673
                     /locus_tag="JOX41_001345"
                     /pseudo
     CDS             14515..14673
                     /locus_tag="JOX41_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008788611.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-binding domain-containing protein"
     gene            complement(14680..15873)
                     /locus_tag="JOX41_001346"
     CDS             complement(14680..15873)
                     /locus_tag="JOX41_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAY6449100.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDRKYLYKYVDAFGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRANVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVLENDTKKKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQQVMKKRPKAEPFVIDGRGNFLFVNHKGKPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            complement(15952..16158)
                     /locus_tag="JOX41_001347"
     CDS             complement(15952..16158)
                     /locus_tag="JOX41_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HAY6449101.1"
                     /translation="MSNAQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEQVIDKLDAI"
     gene            complement(16151..17293)
                     /locus_tag="JOX41_001348"
     CDS             complement(16151..17293)
                     /locus_tag="JOX41_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAY6449102.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRYPTTDALEIIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CDGVIRRFDLAINDMCGLLDIPVLSEKYRNGGADCRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRGTKAVQAVEELLLTYNPHG
                     LVFYLITDFVQFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDIADVIESEGVFYE"
     gene            17805..18440
                     /locus_tag="JOX41_001349"
     CDS             17805..18440
                     /locus_tag="JOX41_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAY6449103.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            18594..18671
                     /locus_tag="JOX41_001350"
                     /pseudo
     CDS             18594..18671
                     /locus_tag="JOX41_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646598.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            18916..19032
                     /locus_tag="JOX41_001351"
     CDS             18916..19032
                     /locus_tag="JOX41_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HAY6449104.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            19048..20967
                     /gene="tet(M)"
                     /locus_tag="JOX41_001352"
     CDS             19048..20967
                     /gene="tet(M)"
                     /locus_tag="JOX41_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019117172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HAY6449105.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            21086..21253
                     /locus_tag="JOX41_001353"
     CDS             21086..21253
                     /locus_tag="JOX41_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAY6449106.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(21313..21666)
                     /locus_tag="JOX41_001354"
     CDS             complement(21313..21666)
                     /locus_tag="JOX41_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAY6449107.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            22170..22589
                     /locus_tag="JOX41_001355"
     CDS             22170..22589
                     /locus_tag="JOX41_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009269612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAY6449108.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            22615..22821
                     /locus_tag="JOX41_001356"
     CDS             22615..22821
                     /locus_tag="JOX41_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAY6449109.1"
                     /translation="MICKASSGDEMAVKEILKFYDGYISKLCLRPFYHSESGKIIMQV
                     DEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(23049..23222)
                     /locus_tag="JOX41_001357"
     CDS             complement(23049..23222)
                     /locus_tag="JOX41_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAY6449110.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            23198..23863
                     /locus_tag="JOX41_001358"
     CDS             23198..23863
                     /locus_tag="JOX41_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar diacid utilization regulator"
                     /protein_id="HAY6449111.1"
                     /translation="MELDFSSPYYVVVGQLSDNQQLCQERINPLLELLERVFSYYGQA
                     LLTVHRQQIIILVNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSF
                     LHAKQVCEWIAFHQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLF
                     KKTLACFSKNNGSIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLL
                     VQT"
     gene            complement(23945..25111)
                     /gene="dnaJ"
                     /locus_tag="JOX41_001359"
     CDS             complement(23945..25111)
                     /gene="dnaJ"
                     /locus_tag="JOX41_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HAY6449112.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(25262..27091)
                     /gene="dnaK"
                     /locus_tag="JOX41_001360"
     CDS             complement(25262..27091)
                     /gene="dnaK"
                     /locus_tag="JOX41_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HAY6449113.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            complement(27142..27705)
                     /gene="grpE"
                     /locus_tag="JOX41_001361"
     CDS             complement(27142..27705)
                     /gene="grpE"
                     /locus_tag="JOX41_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HAY6449114.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            complement(27799..28842)
                     /gene="hrcA"
                     /locus_tag="JOX41_001362"
     CDS             complement(27799..28842)
                     /gene="hrcA"
                     /locus_tag="JOX41_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HAY6449115.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            complement(29076..30241)
                     /locus_tag="JOX41_001363"
                     /pseudo
     CDS             complement(29076..30241)
                     /locus_tag="JOX41_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
     gene            complement(30257..30484)
                     /locus_tag="JOX41_001364"
     CDS             complement(30257..30484)
                     /locus_tag="JOX41_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HAY6449116.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            30968..31558
                     /locus_tag="JOX41_001365"
     CDS             30968..31558
                     /locus_tag="JOX41_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HAY6449117.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            31748..32461
                     /locus_tag="JOX41_001366"
     CDS             31748..32461
                     /locus_tag="JOX41_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449118.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
BASE COUNT         9520 a         6618 c         5736 g        10623 t
ORIGIN      
        1 tctataaaca tcaccccaaa taaaacagaa aacagtataa gcattataaa aattatcaac
       61 aaccttgatc cttcttttat agattcagga aacagtataa ttttagtact agataaattg
      121 tttacaccga ttagtgttaa aatatcttta ttcttcttgc taacataacc ctttatgcac
      181 aaaagaacag ctatacttaa agtaacaaat aaataacgta ttccaataga aaaatcacta
      241 taaatactct ctagcatagg accgacaatt gaagaagtca ctactgcaaa tgctggacct
      301 atccaagcaa cattagaatg ttctttctct cttttccttt gtaaatcttt gttgagtatt
      361 aatctattta tttcttctgc aggcaagtta attttcataa ccttatgggg gattatccaa
      421 ttaaaaatcg gaaaaaggta gcctccccaa aaagtatagt gatctgtgtc aatcagataa
      481 taacctgatt ttgattccag aataacatat ctcaaagccg aacgaaaatt tttcatgaat
      541 atccataatc tcactgtttc cacacctaat tcctccaatt ccaattaaat ggatttatag
      601 catcaccaat tatgttaact gcctgaccaa cctcattgat aaaattggca ccactatccc
      661 atgcttcaac aatgctatat atctatcaaa caaaaaatgg aaaactaaat actcgcgcac
      721 ataaatttta cattctgttt tttataagac taataataat cattgaaaaa atttcttatc
      781 ggtggcgcat attcccaatt gattaatgtg atcccatatt ctgcaagtat tttacgagct
      841 tcttctaagt catagtgaga aaaatgcata aaacctgcaa tacgatcacg gactgtgagc
      901 tgtggcttgc ttccaccatc attcataaaa tatccagcag agccactact taaagtgatt
      961 gttacatctt cactttctat tattaagaat tcataatgaa atgctttcaa ctctccacta
     1021 ttatttaaaa gttttatact ccaacttcgt ctaggttgag ttgtcacatt ccctctaaaa
     1081 cttcctataa attctgcaat caccgtatct tcaatcaaaa ttctttcctc atctatttca
     1141 tattcaagac taaacggaaa ttctccatat gtaatctctg gcaatggtgg tgctgtagtt
     1201 ctccaaataa atacaataac tgtgaataga aaaaatccaa cgatcgatat aaatgttatg
     1261 agacctgctc gaagtaaaac ccgatataat aaaaatgctg tatttcgctt tgctatatct
     1321 agaaaaataa aaagtactgc aatcataatg atagtaaaag ttgtaaaaaa gcacattttt
     1381 tgccctccct ttataaacat cgattctcaa attctaaacc aaatcttgat agttcaagtt
     1441 caggtataac gtataccaac catacatccc aattactatt tatgaactta tgattatcac
     1501 tgaataaatc actccatccc cttgttaaaa cttctacatt aattacacct ggttgttttc
     1561 gactagctaa tccaatgaac ttatcaacca tccttatcca ccaaccacga gaatcttgac
     1621 cagaagtaag aaaaacagtt ctcaaggttg atcgagcagt tccttccagt ttttaattaa
     1681 tctccagtta tagataaata cttgatccta tctatatcag gacttctata ttaagcaaaa
     1741 gtttatgtat aaaactaaaa tcttcattca gttgtctccc cgctttttat acgattgtat
     1801 taaaaaacaa tagaagcctt tcaacattat gttactccag taaagttgga attatagttt
     1861 gacggaagaa aagcaagtat agcttttaaa aaaaactgat acattcgcat ctcctgcttc
     1921 atgtatcagt tttttctttg gattaaactg cttcttcacg cagtttttcc gcaaattcat
     1981 ttattttgcg aattcggtga ttaattcccg attttgatat tgcacctgag ggaatcattt
     2041 cccctaattc tttcaagctg acctctggat gttgaagccg aagttctgcg atttcctgaa
     2101 gtttttcagg aagggcatgt agaccgacct ttgcttcgat caattcgatg ttttcgattt
     2161 gtttagaagc cgcatcaatc gtcttgttca gatttgctgt ctcacaattg actagacgat
     2221 tgaccgaatt tctcatatcc cgtacgattc gaacatcttc aaatcggagc attgagttgg
     2281 ttgcaccaat caatgttaag aaatcagcaa ttttttctgc tccttttaaa tacgaaatat
     2341 agccattgcg ccgttcaagc gttcgagcat gtagaccgta ataatttaac atatcgcaaa
     2401 tgtcttggtt atgctgttca taaatagaaa atatttccaa atgataacga ctcgtttccg
     2461 gattattgac tgaacctgag gccataaaag caccacgtaa gtaagaacgc attttttgcg
     2521 aatttcccat aatctcgtcc gaaacgtgtc cattgaacat cataccatcc atgatatcaa
     2581 gatccatcaa cacatctttt gtgccttgct tcaaccggac gatatagaca ttgttctttt
     2641 ttaatttcat ttttttacga acgagtagct cacttcgtac ctgataatga tctttcaaaa
     2701 gagaatagat acgtctggca attgcagcat tttctgtttg gacgttcaaa ataaactgct
     2761 ggttcacaat acctaaagag ccgttcattc gcagcaaagc agctaattcc gctttcgcat
     2821 gttctcgatg aacttccaaa ccagttagtt ctttcttcac atctgcagca aatgacatcc
     2881 tattctcctc ctttctccaa caataaattg cttaatattt tgaaccgaaa actaaacgga
     2941 acaattcttc tactactttg tctccatcgt ggaagacacc accatctttc aattctaaaa
     3001 agtcggtgga aatcactcga catccttcat ttctcaatcc gttgaagtcg tgtgcgactt
     3061 gtactagata ctcatcatag atctctgggt ccatataatc ttcaggcact ttttccgtat
     3121 tgaccaatac tgtatcgata aaaggctgat tcaaatgctt gtgtaaaaca cgtatatgat
     3181 cggcatctgt gaaatgttcc gtttcccctt tttgggtcat gatattacag atatagacgg
     3241 tttcagcagt tgtcttgagc attgcttcgc cgatttctgg tatcactaaa tttggaagga
     3301 tactggtgaa taaacttccg ggtcccaaaa cgaccatgtc ggcgtccata attgctgaaa
     3361 cgacttttcg agccgctttg gcttcacttt tatcatttgt gttgcagaca tacacacggt
     3421 caatggtttt acggttgatc gcgattttag attctcctac tgcagtcgtt ccgtctttaa
     3481 aaacagcatg caaggtcaaa ggagtttctg aagaaggata aacatgtcca tctacatgca
     3541 tcatttttgc taataattga atcgcctcat aagtgcttcc ccgcatctcg gaaactgcgg
     3601 caatgatcag attaccgatc gtatgattgg ctaaaaactg atcttccttt ttgaaacggt
     3661 attggaaaat atcttcatag aattgtggca tatccgataa cgccactaag acatttctca
     3721 agtcaccagg aggagccata gcgatcgatt ctctgattgc accgctgctt ccaccatcat
     3781 ctgcaacagt cactactgct gtgatatctg ctccttgatt tcgtaaactt ttcaggataa
     3841 ctggcagacc agtgccaccg ccgaccacta cgatctttgg ttttcttatc cggtaggttt
     3901 tcattttcac gaccggttca ccgtctcttt ccttttatcc ttgtcccgat gtgtcacatt
     3961 gactttatag tttttcccta aagcatttgc caaacgttca gtcaatgcca cagaacggtg
     4021 ttgaccgcct gtacagccga ttgcaactgt caagctgctt tttccttctt taatgtatcc
     4081 aggcaataca gtttccagaa gatccaaaaa tttatggtag aatgattgcg tttcatcaaa
     4141 ggacatcaca taatcataga ctggctgatc ttttccggtc aatggtctta gttccgggat
     4201 ataatgaggg ttgggcaaaa aacgcacatc catcacaata tccgaatcga tcggcaaccc
     4261 gtatttaaaa ccaaatgata caaattcgat ccgaaatcct tggtctccct ttgatttgaa
     4321 tgactcattg attttttcac gtaattgtcg tggtgtcaat gttgtcgtat caatgatcac
     4381 ggaagcttgg gctttcaagt cgtctagtat cgcccgttct ttacgtatcc cttcagtgat
     4441 caaaccgtcc atcgccattg gatgtgctcg tcttgtttct ttgtagcgag ccactagttc
     4501 ttcgtctgaa gcatctaaaa ataagataga agtgtcgatg aagttcgtat tttcgatttc
     4561 gatcagcatg ttttggattt cttcaaagaa ggaacgagaa cgcaaatcca ctcctaaagc
     4621 catttttgtg actttacctg attctttgat caattcccag aattttggaa tcaatcgagg
     4681 cggcatatta tcgatacaaa aatagcccat atcttcaaaa ctttggatag ctactgtttt
     4741 ccctgcacca ctcatacctg ttatgatgac taattgcaaa ttatctgtca tatttacgaa
     4801 cccctctcac attgtgcata ataaaattat atcatcccgg gcgtatcatt accagttttc
     4861 tttttctttt acaaaaagat ttggaccaaa tatcttttag gatatttgcc ccaaatccaa
     4921 tttttttact tttccgatgc tgtatccaat gcctcgcttc tttcagctaa tgcacgttcg
     4981 atcgttcgat ccgctaaaat agattgagca tcgatcactg ggtaatgatt atcttcagca
     5041 aattcatgca tcaaagataa ttctgtgcaa cctaggatga ctttttcaca gtttaggcgc
     5101 tctaccgctt cctctaagat ttcgtaatag agctcttgat tcaaataatc cgattccttg
     5161 atctcatgat agatcaggta attgattttt tcttgaagcg cagtatcagg aatcactgtt
     5221 tcgaaaccaa gatttttgac ttcgcgttca tagattccag ctttcatact tccttctgtt
     5281 cctagaatcg ctactctccc tgtcgtatgc tgacggacaa gttcatttgc tgcttctctt
     5341 ggcatatgca agataggaat atccgttgcc gcttgtaact cttcaaaaaa gtagtgtgcg
     5401 gtgttacaag tcaacacaat gaagtttggt cgcaataaat tttgtttctc aatatcatcc
     5461 agcagaaacg gcattggatt ttcttctgat cgatctaaaa tataagctgt acgatcagga
     5521 actgttgcat gattgaataa gacataattc aaatattctt gatcttttgt agctttcgtt
     5581 cggtggttga tcaagcgaac aaaactttct gtcgccatcg tgcccattcc gcctaaaata
     5641 ctgaaaaaat tctccatgaa ctagccttct ttcacatgaa aatacttttt gaatcttgga
     5701 atatagttat ggaacatata tttcatcaac aaccagcgct tgattgatcg gtctttttca
     5761 taaaatacag tagtaccgta acgattttct ttgatcattt gctcagctag ttttttgtct
     5821 tcattttccc gagcatattc taaaaagatt tttttgggca cacccatcca taatcttgct
     5881 ttatctgatt gattcgttcc ataggtcgtt tcaacaaagg gtttgttgaa cactcgatct
     5941 tctgtgacaa aacgagccag attcaagccg ttcaatgtca caaagaaact gctacgacct
     6001 tgtctcaaat tgatttcaaa taatttatat tctccatctc taggatcata cttcatatcg
     6061 aaattggcaa agcctgtata ttcgattttt tccaaaaatg ccttaatggt ttgatagatt
     6121 ttttcgttat aatctggcat gatcacaacg taattaccaa tcgatgctgg tgtaggatct
     6181 tctaatagtg gatgaccaag gcacatcatc cgaacttgat gatcttcatc tacatacgca
     6241 tttagcacac gcatattact atcatcaccc gggataaaat cttgtacaat catttcactt
     6301 ttataaccgg cttcgtatat ccggcctaaa attaaatcga actcttctct agtctctaaa
     6361 ataaaagctt tttttcttcc ttcaaattgg acagaaagat actccacact gtttgcaggt
     6421 ttcaaagcaa ctgggaattc aaaaggcaat tcctgttcca aatgtccatt tactaacatt
     6481 tcttctctga cgatcaatgt tttaggatac ggaagatcat attcttcaca aacttcataa
     6541 aagcttactt tattgatcag cctttcaaat aaagaataat caatatatgg acagataaaa
     6601 tattctgaca gctcttgttt atgttgggag atcaattctg catatccatc accacaagca
     6661 atcaaaagat attttttact cttatcagaa tatctttctt ttgccaaacg aagcatcgtc
     6721 tcgataaata cagggtcttt atcaaatcct ggaataactt ctacattgac aattttactg
     6781 tagcgggtag gggctaactg atccgaagca tatgcttggc agattttgcc gtatgcttca
     6841 ttaaaagaac gtgccatacc ataaacgttc atgtcgcttc ctaataatat agggataaat
     6901 tcttcatttt caatactgtt catcattatc tctcacttac tcataatctc ttgtttttct
     6961 tttccaacta cacaaggaat atcataccat aaagaaaaaa gcaatcaaag gaaagtcctc
     7021 cgattgctca attctttttt gaacggattg aacttatagg aagtttttat ctataccaat
     7081 cagtgtagaa agaactacca tgtaatgatt ctagaacact gatattaata aaacaagcaa
     7141 aaattcattt ttttatgttt ttttaactat ctcagctatc tatcctcttt ataccattat
     7201 ttttttcaaa tagtgacctg tataactttc ttttacgtta atgatttctt ctggtgttcc
     7261 agtcgcaagg atcgttcctc caccttctcc accttctggt cctaaatcaa tgatataatc
     7321 tgctgttttg attacatcta gattgtgttc aatcactaaa actgtgttac cagcatctac
     7381 taatctttgt aatacatgca acaagcgggc gatgtcatcg ctatgaagtc ctgtcgttgg
     7441 ttcatctagt atatagaaat tctttccatt agagattttg tgcaattcac tggcaagttt
     7501 catccgttgt gcctcaccac cggacaatgt cgttgctggt tgccccatcg tcacataacc
     7561 taagccaaca tcaacaatcg tttgcagttt gcgatgaatc tttggaatgt gcttgaagaa
     7621 ttctacagca tcctctactg tcatttccaa aatatcagca atgctttttc ctttgtaatg
     7681 cacttctaat gtttcagaat tatatcgttt accatgacat acttcacaag gaacatagac
     7741 atcaggcaaa aagtgcattt cgatcttaat aattccatcc ccgcgacaag cttcacaacg
     7801 accgcctttt acgttgaaac taaaacgccc tttcttataa ccccgcattt ttgcctcgtt
     7861 cgtttgagca aataacccac ggatatcatc aaatacactt gtataagtcg ctggattact
     7921 tctcggcgtc cggccgattg ggctttgatc gatatcgatg atcttttcga tactttcgta
     7981 gccggaaatt gtcttgaatt tacctggctt agcagaattc ttatttaatt tttgcgctaa
     8041 cgatttcttt aagatactat tgaccaatgt actctttcca gaaccagaca cacctgtgac
     8101 tgctacaaat tctcctaatg gaaattcaac actaatattt ttcagattgt tttctgaagc
     8161 accagtgatc ttgattgctt tcccattacc tttacggcgt tcttttggta cagggattga
     8221 ttttttccct gaaagatatt tccctgtcaa agaattttca tcattagcta cttcttcagg
     8281 agtgcctgca gccacgattt gtccgccttg ttctccggcc ccaggtccga cgtcaatcaa
     8341 ataatctgct gcccacatcg tatcttcatc atgttcgact acaacgaggg tgttgccaag
     8401 atcacgcatt ttctttaatg agccaatcag tcgatcgttg tcgcgttgat gcaatccgat
     8461 cgatggttca tctaaaatat acaaaactcc agaaagattc gatccaattt gtgtagccaa
     8521 tctgattcgc tgcgcttctc ccccagataa tgttccggaa gcgcgactca aagttagata
     8581 gtctagtccc acattttcca agaatgaaag tctgtcattt acttctttta aaatcggttt
     8641 ggcaattact ttctcttgtt cagataacgt taagtttgag aagaaatcta ctgctttttg
     8701 aatagacaac tcatttgttt gcccgatatt cgttccattg atttgaacag atagagcttg
     8761 gggattcaat cgataacctt tacatgtctg acaagttaat tctgtcatat aaagacgcat
     8821 ttgctcacgc gtgaaatcac tgttcgtatc atgataacga cgctcgatat tcttcaatac
     8881 cccttcgaaa gtcgtttcta catcgcgaac gccaccaaaa tcattttcat aatggaaatg
     8941 gaaaagatca tctgtcccat tcaagatgat ctcctgatgc tcttccggta attcttcgaa
     9001 tggtgtatct aaatcgatac cgaaactttc acaagcctgc gctaacattt gaggataata
     9061 ctgagagctg attggattcc atggaacgat agcaccttga ctaagtgtct tcgttctatc
     9121 tggaatcact aaatcttgat cgacttctaa tttgacacct aaaccatcac agtctggaca
     9181 agctccaaaa ggcgcattga atgagaacag tcttggttct agttcgccaa cagtaaatcc
     9241 gcaataagga caggcatagt gttcgctaaa caacatttct tcttcaccga tcacgtcaac
     9301 cagagcatag ccgtctgcta atcgcagggc cgcctctaaa gaatcaaata ggcgagaacg
     9361 aatcccttct ttcacaatga tccggtcgat gacgatcgcg atatcatgtt ttttgttttt
     9421 ctccagctca ggcacttcac ttaaatcata gatctcacca tcgactcgaa cgcggacgta
     9481 tccctctttt tggattcgtt cgaatatttt tttatgttgt ccttttttct ttaccacgat
     9541 cggtgccaac acttggatct ttgtgcgctc aggcaaagcc attacttgat ctgccatttg
     9601 atctactgat tgactggtaa tctcgatatg atcgttggga caaatcggat gtcctacacg
     9661 tgcaaacaac aagcgtaaat agtcattgat ttccgtcaca gtacctactg tcgaccgagg
     9721 atttttactt gttgttttct gatcaataga aatcgccgga ctcaatccgt cgatgctatc
     9781 tacgtccggc ttatccattt gtcctaaaaa ctgacgagca taagcagaaa ggctctctac
     9841 gtatctccgc tgcccttcag cgtacagcgt atcaaatgct agggaacttt ttccagaacc
     9901 ggacaaacct gtaacgacca cgaatttatc tcgtggaatc gttacatcta tatttttcaa
     9961 gttatgggca cgtgcaccat gaatcgtaat tttatcgtta gccatgttgt cctcctactt
    10021 tgaagctttt aattctaaaa tcatatctcg cacattcgcg gctgtttcaa aatccaaagc
    10081 ttttgccgca tctttcattt ctttttctaa tttcatcaat aacgtgtctt tttcttcctt
    10141 cgtcatttct tcgtacgaga cttgtaccgc ttcttttgta tcatcttccg attctttcgt
    10201 aatagaaatc aaatctcgga tttctttaat gatcgttttt ggaacgatcc catgttcttc
    10261 attgtacttc tgctgaatcg tacgacgtct tgacgtttca tccatcgcta gacgcataga
    10321 atctgttact ttgtctgcgt acatgattac tttaccttct tcattccgag cagctcgtcc
    10381 aatcgtttgg actaaggaac gttcactacg taaaaagcct tctttatccg catccaagat
    10441 agcaacaagg gaaacttcag gtacgtctaa tccttcacga agcaaattga ttccaactaa
    10501 cacatcaaat tcacctaatc gaagatctcg aatgatttct gttcgttcca gcgttttgat
    10561 atcactatgc aaatatttga ctttgatccc taattctttg aaataatctg tgaggtcttc
    10621 tgccattttt ttcgtcaatg tcgttacaaa cacccgctgg tctttttcga ctcgttcatt
    10681 tatttcgcct actagatcat cgatttgtcc catgattgga cgaacttcga tcactgggtc
    10741 aagcagccct gtcggacgga tgatttgttg gataacggta tctgtttgtt catgttcata
    10801 tggtcctggc gtcgcagaga cataaatgat ctgattgaca tgtttttcaa actcttctaa
    10861 ccgaagtggc cgattgtcta aagcagatgg caaacggaaa ccgtaatcta ctagcatctg
    10921 ttttctcgct cggtcaccat tatacattcc tctgatttga ggcatggtta cgtgcgattc
    10981 gtccgccacg atcaaaaaat cttcaggaaa gaaatccaat agcgtataag gcggttcacc
    11041 ttctttacgt ccgtccatat gccgagaata attttcaatt cccgacgtgt agcccatttc
    11101 taacatcatt tcaatatcgt aattggttcg ctgttctaaa cgttgagctt ccagaagttt
    11161 gttttcattt cgcaagacag ttaaacgctg ttctaattcc tctttgatat tcgctacggc
    11221 atgctccata tgttcatcat tcgtcacaaa gtgagtcgcc gggaagattg ctacgtgttc
    11281 cgtttctcct aaaacttcac ctgtcagtgc attgacttct cggatacgtt cgacctcatc
    11341 tccaaaaaac tccacacgta aggcacgttc atctcttgaa gccggaaaaa tctccacgac
    11401 atcaccgcgc actcgaaaac gaccgcgctg aaaatctata tcatttcttt cgaattggat
    11461 actgactaag tcacgaatca actgattgcg atctagttct gctccctgtc gaatcgaaac
    11521 tacttgtttt tggtactcaa aaggcgagcc taatccaaaa atacatgaaa cggatgcaat
    11581 gacgatcaca tcatttcttt ctaataatga actagtagcc gaatgtcgta atttgtcgat
    11641 ctcatcattt acacttgaat ctttttcgat atacgtatcg cttgaaggca cataagcttc
    11701 aggctgataa taatcataat aagaaacaaa atattcaaca gcattgttag ggaaaaattc
    11761 cttgaattcc ccgtacagct gaccagccaa tgttttgtta tgggcaataa tcagtgttgg
    11821 tttattcact ttctcaataa gattggaaat cgtatatgtt ttccctgttc cagtcgcacc
    11881 taataagatt tgtgcttttt tcccgccgac tacgccatcc actaattggt taatcgcttc
    11941 aggctgatca ccagccggtt ggtatttcga gacaagctca aagtgtcggg aggtatctct
    12001 ctcaatcatt cttcgtcctc cttttcattc attccttttc attttacgac caataaaaag
    12061 aaaaggaaag caaaggcatt ccttactaaa aaattatacc acaccgaaca tactttcgcc
    12121 acttttttat cttattatac atgttatgtt ttataacata aaatgttaga aactcgcatt
    12181 tttttcattt tttcgagctt acagtcttgt ctgattcagc acttttcgcc tataataata
    12241 aaatattgga aatttaggag gttgattatg aaaagaaagc atttatttca ctcatttgtt
    12301 ttcttaatga caggacttgt gacacttgcg tttggtcatg ttgcacaagc tgacaacact
    12361 acaacggcag agtcaagcac aagcgagaca atgcaaaaaa tagagcccaa aaaagacgta
    12421 tacgtaattg ccagtgactc tgcttttgct ccatttgaat ttcaaaacgc aaagggcgag
    12481 tacgaaggca tcgatgtaaa attgatggaa aacatcgcca aactgcaagg atttaacatc
    12541 cgaatggact accgtggttt ctctgctgct ttgcaagctt tggaatcagg acaagcagac
    12601 ggaatgattg ccggaatgac tgtaacagat gaacgaaaga aaagctatga tttttctgat
    12661 tcttactttg atagcgggat ccaattagct gtcaaaaaag gagatacttc gatcaagtct
    12721 tatgaagatt tgaaaggaaa aacagtcgga gcaaaagttg gtaccgaaag tgctgaattt
    12781 ttaagcgacc atgaatctga atatggctat tctatcaaat attttgatgc tgctgatcaa
    12841 ttgtacgacg ggttaaaagt tggcgcaatc gatgcaatga tggatgatta tccggtaatc
    12901 ggttatgcga tcaaacaagg acaagaattg gaaacaccga tcaaaaaaga atctggcgga
    12961 aaatatgcat ttgccgttaa aaaaggacaa aatcctgagc ttcttaatat gttcaatgaa
    13021 ggattgaaag aattaaaaag aacaggcgaa tacgataaga ttattaaaga atatgtagcg
    13081 gatggttcag aaacttccag tgagtcttcc actgctgatg aatcaacatt tcttggactt
    13141 atccaaaaca actatcaagc attgttgaaa ggactttgga gaacaattct cctaactttg
    13201 atctcctttg ctttggctat agtaatcggt gtgatttttg gattattcag tgtagcacca
    13261 atacgcgctc ttcgcacaat tgctagtatt tatgtcgata tcatccgagg aattccaatg
    13321 atggttcttg cgttctttat tttctttggg ttgcctggta tcgttggatt tacgattcct
    13381 gacttccttg ctggtgttat caccttgact cttaacgcaa gtgcttatat cgcagagatt
    13441 gttcgaggcg ggatcaacgc cgttcctgtc ggacaaatgg aagcttccag aagtttaggt
    13501 ctttcttata atcggacaat gcaaaaaatc attttgccgc aagcgatacg catcatgatc
    13561 ccatcattcg tcaatcagtt cgttatctca ttaaaagaca caacgatcat ttccgcaatc
    13621 ggtgtagtcg aattgctgca aactggtaag atcattgttg cacgtacaac acaaagtacg
    13681 tatgtttact tgatcattgc gatcatgtac ttgattttga tcacagcatt gacaaaatta
    13741 gcaaaagttt tagaaaagaa ggtgaagtaa gatggcagaa aaaatcttag ttgagcattt
    13801 agtcaaaaaa tacggcgata acacagtatt aaacgacatc aatgtatcca tcaacgaagg
    13861 agatgtcgtc tgtatcattg gcccttcagg ttcaggaaaa agtacattct tgcgttgctt
    13921 gaatcgttta gaagaacctt ctgacggtga aattattatt gacggcgccc acttgatgga
    13981 taaaagcaca gatatcaact tggtgagaca acatatcgga atggtattcc aacactttaa
    14041 cctattccct catctttcta ttttggaaaa catcatttta gcaccgatgg acctgaagaa
    14101 agaatctaga gaagaagcag agaaaaaagc aatcaaatta ctgcagacag ttggtctaga
    14161 agataaaaaa gatatgtatc ctgaaatgct ttctggtgga caaaaacagc gtgtggctat
    14221 tgctcgtgct ctagcgatga accctgacat catgcttttt gatgagccta cttctgcact
    14281 cgatcctgaa atggtcggtg atgtcttgaa cgtcatgaaa aagttagcag aacaaggtat
    14341 gacgatggtt atcgttacgc acgaaatggg gttcgctaaa gaagtggcca atcgcgtcat
    14401 gttcattgac gacggaaact ttttagaaga tggaacgcct caacaaatct ttgaaaatcc
    14461 gcaaaatgaa cggacaaaag atttcttgaa taaagtatta aatatttaaa ataaattata
    14521 tatgtctttt tgactatctt tttatatctt cttaaatgtc cgcaaagcct tattttatag
    14581 gctctacggg cattttgctt ttgtggtaaa cctcacatat ctaggtctat cttcttatat
    14641 tttcactatc aagcgtggtt aaaatcgtgg taaatacttc tatgcaatta gacgctgaac
    14701 ctctgatttt gcggtatcta tggacgcatg agcataccag ttcattgtga tactgatatt
    14761 tgaatgcccc atgatatact gtaaatcttt tgggttcatg ttcttgcttg ccagtcttgt
    14821 gcagaatgta tggcgtagcg tatgcggtgt gatatgtggc aatggattgt ccttgtggtg
    14881 cttgttgtat ttctttacca tacggataaa taaggcgtta taatcaatcg caactttggg
    14941 cttgccctta tgattgacaa ataggaagtt gccccgtccg tctatcacaa atggttctgc
    15001 ctttggacgt tttttcataa cctgttgaaa tgcctgtatc gtttctttgc ttaatggtac
    15061 ttgccttatt ccgctttttg ttttaggcgt ttcaatataa tagccctgtt ccttgctctt
    15121 tagtaactgg tggtcgataa tcacaacttc attcttgaaa tcaatgtcgg ctactgtcag
    15181 tccgcacagt tccgaaatac gaagtcctgt ctttaacagt atcagcacat catcataatg
    15241 cttgtgatac acattgtccg tcttgatgaa tgagagtaag gcttgttcct gttcctctgt
    15301 caatgcgact ttctttttgg tatcattttc taggacttca ctcaacttga aatcaaaggg
    15361 atttttcctc acataatcat cttgaatggc tatgtagaat gacgctttta acgagcgttt
    15421 atggttgtta atggtattgt aggaaaagcc tttgtctttc atgcgtaacg cccattcctt
    15481 agcgtcagag ggtttgattg tatcaatgct cctagcacct aacttgtcct ctttcaataa
    15541 ccgcatgagt tgttcccgtt gtttctgtgt gcttttcttc acatttgccc tctgtgcgtt
    15601 ctgtttggca taaagttggc aaagcgtcat tttcttgcca gtgctgtcga taccgtcctc
    15661 aatatcccgt cttatctgct gttccagttc tcgaagtgag ggtttttccc gttttccctt
    15721 tggtgtcggg tctgtgggtg tcaatctcca agcatacaca tattttgtgt ttccaaatgc
    15781 gtctacatat ttatataagt attttctgtc tgttcgttgg ctctctccag tatgcaggat
    15841 acgacctttg ttatcccgtc ttttttcttt catggtgtct gctcctttcc ttgttggaaa
    15901 gagccttgat atgacttgtg ttcatcataa cacatacaag gctcatttgc attagatagc
    15961 gtccaattta tcaatgacct gttcaaactg tcggcgttta atctgtatgc ggttgccatt
    16021 cataatgagc cagccagcgt ccttgttttc ctctgccaat cgtcttaact tgttttctcc
    16081 gatacggaaa tactttgacg cttcttcaat ggtaagggtg tatttttccc atacgggaat
    16141 atcctgtgca ttactcataa aacaccccct cactttcgat tacgtctgct atgtccgtac
    16201 acatctgttc cacaagcatt tcctgctttt cagagaggtg ggtacattca tcaatcattt
    16261 tcatgtagtt tgagcctgtc agcctgtcga tttcctctat catcacgatt gacggcatga
    16321 cctgtctttc cagccattgc agagtgcgtt ccatattgac aggtacgggg ttcatttcaa
    16381 aaggtaaact gtcatgggaa atgaatatct cccacagcgg atagtcggga aattgcacaa
    16441 aatcagtaat aaggtaaaac accagcccat gagggttata tgtcaataac aattcctcaa
    16501 ctgcctgtac tgcttttgta ccacgcagac gaatttcaaa acgattgata atatccgtat
    16561 gtttcttttt ggttgcctgt tccttttgtt tttcatacag gcagaagtat tttgtgcttg
    16621 cctttgaacc gatataaagg gtgcttgcta aattacggtt ttttccgctt agttttccac
    16681 cctgcacatt ttcataattt ttacagcgac aatccgcacc gccatttctg tatttttcag
    16741 acaaaacggg aatatccaac agaccacaca tatcattgat tgccaagtca aaacgtcgga
    16801 taacaccgtc acagtcaaga cagcggttta aaaatgaata ccaatctctg ttctgtgcct
    16861 gcaagacata ttccatgttg cgtgagcctg ccccttttaa ttccaagaat acgcccatgt
    16921 gttcgtcatc agaagccatg accttgattt ctccgtaggc gtaatgctct ttatagccat
    16981 aatacccata gtcataatgg ataaaataat ctgctttcat gccaagcacc tttcggataa
    17041 tttccaatgc gtcagtcgtt ggataacgga cagacagata atcaacgagc agataaaaag
    17101 gcttatcgca gatataataa ttcagacaac gcaggataat attttgtgtt tccttgctgg
    17161 cgttggcttt tccgttctca aagcggttga tactatatct tgatacatgg gtaagacttg
    17221 caagttctcc ttgtgaaaga ccgcttgcaa gacgtttgtt cttcatttca agtgcaaatt
    17281 ctaaattgtt cattgtattc ctccaatccc acaatagcct tgaaatacct gtaaacctct
    17341 attcaaaaag tgtgatatgc actatcttct taaaacttct cattactact cacaactttg
    17401 ggattgtatg gtttttgact tgtcttttgt gaaatagtgc ccccctgtta gataacgggg
    17461 gcacagacaa ggctcgcagg ctcgccagcc gacaaagcat ttcttcccct tgacacaagg
    17521 tgtcatggcg gtaagcctga gaggcttccg ccaccgtgtc agaaatactt tgtcagcaag
    17581 ttctgttttg ccttttctaa caagttccat ttcaaccgat attcatatct acggatttaa
    17641 tcagataggt atttcttttt gaatgttttt atatttcatt ctattgtgct tattcgatta
    17701 caagaacata gtaattctta tatgcttatt tgtcaatatc tttttttgcc tttacaaatc
    17761 atattaagca tgatagactt ataatagcga agatataacg agatatggag ggttatgcaa
    17821 tgaaaataag ccatttagga aataatatac agaccataag aaaatttagg ggaatgaaac
    17881 aacaggaact tgcggacaaa atcggtatca atatgcagag cctttccaag attgaaagag
    17941 ggttgaacta tcctgcctat gaaacgctgg aaaagataat ggaagtgctg gacgttacgc
    18001 ccaatgaatt gttgtcggga gaatggaagt atgtcaatca atctgaaaag gaagtctgtc
    18061 agtttttaag agccgaagaa cgtctaaatg cagaactgaa acatggacac tatgataact
    18121 tctttgacag cgaggaagaa tggctggaat atgagttaga aaagttacgg gaatatatta
    18181 cagactatat caacgggaaa agcattgaag cgtccgacct ttacccaatc aaagaattta
    18241 tccagcattt gaagtttcaa aaattattag accgctatga tgatttatac agtatggata
    18301 tgtttgggga aagcatagag ggacataagt ataagacacc ttatcaagtc gtgaaaatga
    18361 taaacccgaa ctcaaaagaa gatatggaac tgttacgaga agtattaagg aataacaatt
    18421 ttgatgatga ggacgagtaa cttttttcct cttgcgagaa gatacagcaa acaaaaagcc
    18481 cgatcaagag tgcaaagcac caccaatggt ggcaaagctc ttgacagggc tttttctttt
    18541 ctgttgtggg caatcaagag gaagaaaggg ataaaatctg atttgtggta aatcaggcaa
    18601 aggcaacgca ggtatctcaa tttgatttgg tacttgaaaa gaacgggagt aattggaaga
    18661 ttatagaata acaaatattg gtacattatt acagctattt tgtaatcacg tactctcttt
    18721 gataaaaaat tggagattcc tttacaaata tgctcttacg tgctattatt taagtatcta
    18781 tttaaaagga gttaataaat atgcggcaag gtattcttaa ataaactgtc aatttgatag
    18841 tgggaacaaa taattggatg tcctttttta ggagggctta gttttttgta cccagtttaa
    18901 gaataccttt atcatgtgat tctaaagtat ccggagaata tctgtatgct ttgtatgcct
    18961 atggttatgc ataaaaatcc cagtgataaa agtatttatc actgggattt ttatgccctt
    19021 ttgggttttt gaatggagga aaatcacatg aaaattatta atattggagt tttagctcat
    19081 gttgatgcag gaaaaactac cttaacagaa agcttattat ataacagtgg agcgattaca
    19141 gaattaggaa gcgtggacaa aggtacaacg aggacggata atacgctttt agaacgtcag
    19201 agaggaatta caattcagac aggaataacc tcttttcagt gggaaaatac gaaggtgaac
    19261 atcatagaca cgccaggaca tatggatttc ttagcagaag tatatcgttc attatcagtt
    19321 ttagatgggg caattctact gatttctgca aaagatggcg tacaagcaca aactcgtata
    19381 ttatttcatg cacttaggaa aatggggatt cccacaatct tttttatcaa taagattgac
    19441 caaaatggaa ttgatttatc aacggtttat caggatatta aagagaaact ttctgccgaa
    19501 attgtaatca aacagaaggt agaactgtat cctaatatgt gtgtgacgaa ctttaccgaa
    19561 tctgaacaat gggatacggt aatagaggga aacgatgacc ttttagagaa atatatgtcc
    19621 ggtaaatcat tagaagcatt ggaactcgaa caagaggaaa gcataagatt tcagaattgt
    19681 tctctgttcc ctctttatca tggaagtgca aaaagtaata tagggattga taaccttata
    19741 gaagttatta ctaataaatt ttattcatca acacatcgag gtccgtctga actttgcgga
    19801 aatgttttca aaattgaata tacaaaaaaa agacaacgtc ttgcatatat acgcctttat
    19861 agtggagtac tacatttacg agattcggtt agagtatcag aaaaagaaaa aataaaagtt
    19921 acagaaatgt atacttcaat aaatggtgaa ttatgtaaga ttgatagagc ttattctgga
    19981 gaaattgtta ttttgcaaaa tgagtttttg aagttaaata gtgttcttgg agatacaaaa
    20041 ctattgccac agagaaaaaa gattgaaaat ccgcaccctc tactacaaac aactgttgaa
    20101 ccgagtaaac ctgaacagag agaaatgttg cttgatgccc ttttggaaat ctcagatagt
    20161 gatccgcttc tacgatatta cgtggattct acgacacatg aaattatact ttctttctta
    20221 gggaaagtac aaatggaagt gattagtgca ctgttgcaag aaaagtatca tgtggagata
    20281 gaactaaaag agcctacagt catttatatg gagagaccgt taaaaaatgc agaatatacc
    20341 attcacatcg aagtgccgcc aaatcctttc tgggcttcca ttggtttatc tgtatcaccg
    20401 cttccgttgg gaagtggaat gcagtatgag agctcggttt ctcttggata cttaaatcaa
    20461 tcgtttcaaa atgcagttat ggaggggata cgctatggct gtgaacaagg attgtatggt
    20521 tggaatgtga cggactgtaa aatctgtttt aagtatggct tatactatag ccctgttagt
    20581 accccagcag attttcggat gcttgctcct attgtattgg aacaagtctt aaaaaaagct
    20641 ggaacagaat tgttagagcc atatcttagt tttaaaattt atgcgccaca ggaatatctt
    20701 tcacgagcat acaacgatgc tcctaaatat tgtgcgaaca tcgtagacac tcaattgaaa
    20761 aataatgagg tcattcttag tggagaaatc cctgctcggt gtattcaaga atatcgtagt
    20821 gatttaactt tctttacaaa tggacgtagt gtttgtttaa cagagttaaa agggtaccat
    20881 gttactaccg gtgaacctgt ttgccagccc cgtcgtccaa atagtcggat agataaagta
    20941 cgatatatgt tcaataaaat aacttagtgt attttatgtt gttatataaa tatggtttct
    21001 tgttaaataa gatgaaatat tttttaataa agatttgaat taaagtgtaa aggaggagat
    21061 agttattata aactacaagt ggatattgtg tcctgtatgt ggaaataaaa cacgattaaa
    21121 gataagggaa gatactgaat taaaaaaatt ccccctctat tgtccgaaat gcagacaaga
    21181 aaatttaatt gaaataaagc agttcaaagt aactgtgatt acagagccag acgcaaagac
    21241 gcagagccga taaaatgaga ttaatacaat ctcattttat cggctctttc cgttatgtat
    21301 ggattctttt aattagtctt cgatgtttct tgcttcgttg ataccgctgg ctaaagattc
    21361 cattaaggat agttctttgt ctgtaaagct atccatgtat ttctctatct gtaatcgtcg
    21421 ggtgcttttt accaagttat tagcaggtaa gaaaaattca tcaacggaaa catgaagtaa
    21481 cgatacaagg tcataaagaa cttgtatgct ggggtgttgc cctttatttt caatattagt
    21541 taagtaccgt gggtcaattt caatcaatgc tcccacttgt tcacgagtta aacctcgttt
    21601 caatcgagct tctttaatgg ctaaaccaaa ggctctaaaa tcatatttat cttctttttt
    21661 acgcatagta gaccacctct atacatttta ttgttcctac tgaattaaaa acaggtatag
    21721 aaaaacgtgt tatatggttt ataggtttat atttaataaa aagcactact aaacgccaat
    21781 aaaaaaaacc gttatatggt agtgctattt acgctgttaa aatattgtat attacttcca
    21841 aatggcggtt tgttggaggt caacgtcgcc atgaagtaca tcatatacaa taaatttcct
    21901 tacattgggt tcttgtcaaa aaaagtcgtc tatctgcaat agataagtac gtccaccaat
    21961 gtggttttat aaatcatata gatagaataa cagaagcatg taaacagaga aataaatctg
    22021 tttatatgct tttttggcta ttcagaactt ttttacaaag tttatttatc agtaatgcaa
    22081 caaatccccc tttcacattg ggactaagag tgaaaggaga taaacgagca aggctcactt
    22141 cctttcctag acagaaaggg ggtgagatta tgaggacatc ttctttcgag catatcgtca
    22201 gattacagtt caattcttta atgctgattg tcattaagaa caaagtgaaa agtcgaaaca
    22261 gacagcttgc aagacattct aaacgtgaag tattgttttg tgaaatagcc gaaacgaaac
    22321 aagttgaacg tggaacgatt gatacctgtt tttatgattg tgtatcattt aaagtcttgc
    22381 actttacaat ttatgtatct gatgaaacac ttggtacagt tttacataga ctatcagaaa
    22441 aacagcgtag tgcgatttta ttacgttatt ttcaaggaat gaacgacaga gaaatttcag
    22501 aactgtacca tgtatcacgt tctgctattt gcagtagaag aactagagga ctaaggaagt
    22561 taaaaatgct tttgagcgaa aggaagtaaa gattatggct atccctcttt tgaattgatt
    22621 tgcaaagcgt caagcggaga tgaaatggca gttaaagaga ttttgaagtt ttatgacggt
    22681 tatatttcta aattatgctt gcgtcctttt taccactctg aaagtggtaa aatcattatg
    22741 caggttgatg aagaactaaa aggagaaatt catacagaca tgatgaaagc aatattgaaa
    22801 tttgaaatcg gagtgaagta atcaactgta taaaaaaatc gggagataca cagtttcgtg
    22861 ttatctccct tagtagtttt acggtcatat caaggctcat tcaatcgtgg taaattcgtg
    22921 gtaagatgag tgtttttcta tacttcaaaa tgcttgaatg tatagtgttt atgcggataa
    22981 ttgaaaatta gatataaaat ttaataaaaa ccaaaaatgc acggtcgcca tgaagggacc
    23041 gtgtattttt atcttcttat tttctcacct aatcgtatca gccgcatcgc ttgttttcct
    23101 gcacaaacaa gcaatcgctc tacctgttcc atcgcataag aaagtaccat cggttcattg
    23161 atgatatcaa gtacatagtc gataccaccc tcacttaatt gagcttgatt tttcttctcc
    23221 atattatgta gttgtgggac aactttctga caatcagcaa ttgtgtcaag aacggatcaa
    23281 tcctttattg gagttgctcg aaagggtctt ctcttattac ggacaggctt tgctcactgt
    23341 acatagacaa caaatcatta tcctagtcaa tcggatttcc agagcctcat tgctatcatt
    23401 gcttgataaa atccagacaa agtttaataa aatgtatcag ttacagctaa actttggaat
    23461 tgggtcgctt tgttatacag agcaagagac accgcaatct ttccttcatg ccaaacaagt
    23521 ttgcgaatgg atagctttcc atcaatctgt gaacgagatc cgcttttttg aagatttaga
    23581 cctcgggatc gttttaccag caatcccgtc agatcaacga acattatatg taaaacgtat
    23641 tttgaaaagc ctgacagaag aagaagtaca tttgttcaag aagactttgg catgcttcag
    23701 taaaaataac ggaagcatca aaaattgctc agaagaatta tttattcata aaaacacctt
    23761 gcaatatcga ttgaacaagt tccattctct cactggttat acccctagaa actatgacga
    23821 ttatcatatt ctaaagctgg cttttttgtt ggtacaaaca tgacaactac aaaaaaacca
    23881 ggcgaacata tgattgttcg tctggttttt aattattaat gacttagcgt ttttactaga
    23941 aaaactactt ccgctttttc ccgccaaaag catctttaaa cttatcgaag aaaccgtctt
    24001 cttgctgttc ttcaactttg atgccgccag cttcagcgaa tgcacgtaat gcttctcttt
    24061 gttgttcatt tagatttttc ggtgtgatca gttttacttt gacatgttgg tcgcctgttg
    24121 caccaccacg taacttcgga gcgccttttc cacgtaaacg gaagttcgta cctgtctgtg
    24181 ttccagcagg gatcttcaat ttcacatctc catggacagt tggtacttgg acttcatccc
    24241 ccaaagctgc ttgtacaaaa cttaaaggca attcatagta aatttcagaa ccttcacgat
    24301 caaagatatc actttcttct acacggaaga ccacatacaa atcaccaaat ggtccgccgt
    24361 tttctccagc ttctccttga ccagctaaac gcatttgttg tccttcttct acaccagctg
    24421 gtacattcac tttaactgaa tgtgctttct tctcatgtcc tgagccatga caggttggac
    24481 aaggttcttt gatttctttc cctgtcccat gacaaacatc acaagtttga cggctcatca
    24541 ctcgtccaag tggtgtttgg cgttctacat taatcgtacc tgcaccatga catttatgac
    24601 aagtagttgg ttgtgtgcct ggttttgcac cgttcccacc acaagtatga cagatttctt
    24661 cccgattata cttgatttct ttttctacac caaaaatcgc ttcttcaaaa gacaagtcga
    24721 ccgtatattg caaatcagca ccttgacgag gcgcatttgg atcgactgac cgaccgcctc
    24781 ctccaaagaa agagtcgaag atatcttcaa aaccaccgaa gccgccacca gagaagccgc
    24841 cgaatccacc aaatccgcca ccagctccac cagcaccgta atttggatct gtgcctgcat
    24901 gcccgtattg gtcatatgca gcgcgttttt gcgggtcact taaaatctca tatgcttctg
    24961 atacttcttt gaatttttct tccgcatcag gttctttatt gatgtcagga tggtattttt
    25021 tcgaaagctt acgataagct ttctttattt catcttctga tgctcctttt gagagcccta
    25081 agacttcata ataatcacgt tttgttgcca taggctttcc tcctattggt tctcatcatt
    25141 ttcacgtcgc ttgttatcat atcatatttt gtttgaaaca aaaaccgata cttcaaacta
    25201 tttttcaaaa gaaaaagcca aagtagcaac tttggccttc tctcgaaatt cagtgaactg
    25261 attatttatc gtcgccatcg acttcttcaa aatcagcatc aacgacatca tctgctccgc
    25321 cttgagctgc ttctgggttt tcttgagctt gttgttgtgc cgcttgttcg tatagtttaa
    25381 cagtcaagtt ttgaacgatt tcgttcaatg catcgcgttt agttttcatt tcttcgatgt
    25441 tgtttgcttc aacagcggct ttcaattcat cgcgagctgt ttctgctttt ttcacttctt
    25501 cttcgtccac tttgccttct aattctttca atgttttgtc cacagagaat agcaatgcat
    25561 ctacatcatt acgtaggtca acttcctctt tacgagcttt atctgcttct gcatttgctt
    25621 ctgcatcttt taccatacgt tcgatttctt cgtctgttag acctgaagaa gatttgatcg
    25681 tgattttttg ttctttttgt gtacctagat ctttcgcaga tacatttaca atcccgtttt
    25741 tatcaatatc gaatgttact tcgatttgtg gaataccacg aggagctgct ggaatatctg
    25801 tcaattggaa tcttcctaga gttttgttgt cagcagccat tgggcgttca ccttgtaata
    25861 catggatgtc tactgctggt tgattatctg ccgcagttga gaatacttgt gatttacttg
    25921 ttggaatcgt tgtattgcgg tcaatcaatt tagtgaacac tccacccatt gtttcgatac
    25981 ctaatgacaa tggtgtaacg tcaagtaaaa caacatcttt cacatcacca gtgatcacgc
    26041 caccttggat agcagcaccc atagcaacta cttcatcagg gttaactgat ttgtttggtt
    26101 cttttcctgt ttctttacgt actgcttcta caactgcagg gatacgagta gatccaccga
    26161 ctaaaataac ttcgtcgatt tctgattgtg ataaacctgc atcttttagc gcttgacgta
    26221 ctggtacttt tgtacgttct actaagtcag ctgttaattc atcaaatttt gcacgtgtca
    26281 atgtcatttc caaatgcaat ggtccagatt ctcctgctgt gataaatggc aagctgattt
    26341 gtgtgcttga tacgccagat aaatcttttt tcgctttttc agcagcgtct ttcaagcgtt
    26401 gtaaagccat tttgtcttga gacaagtcaa tgctgttttc ttttttgaat tctgctacca
    26461 tgtagtcgat gattttgtta tcaaagtcgt ccccacctag atggttgtcg ccagctgttg
    26521 acaatacatc aaagacaccg tctcctagtt caaggataga tacgtcaaaa gtaccgccac
    26581 caaggtcgaa tactaagatt ttttcgtcgc gatctgtttt atctaaacca taggcaagag
    26641 cagctgcagt tggttcattg acgatacgtt ctacttctag accagcgatc ttaccagcat
    26701 cttttgttgc ttgacgttgt gcatcattaa agtaagctgg cacagtgata actgcttttt
    26761 cgactttttc acctaaatag tcttctgcga atcctttgat atattgaagg atcattgctg
    26821 agatttcttg tggtgtatat gatttacctt ctacatctac tttgtaacct gcttcaccga
    26881 tatggcgttt gattgatgaa atcgtatttg ggtttgtcac agcttgacgt tttgcaactt
    26941 cccctacttg gatttctcca tttttgaatg atacaacaga aggtgttgta cggtttcctt
    27001 ctgggttagc gatgattttt gcttcgtttc cttccaatac tgctactgca gagttagtcg
    27061 tacctaagtc aataccgata attttactca taattaacgt ctccttcttt aattgaaagt
    27121 gtaagtttta tatccgcaca attattgtgc aacaatgacc atggttggtc ttaacacgcg
    27181 atcatgtaat ttgtagcctt cttgtagtac ttctacaatc gtatcggctg gtgtatcttc
    27241 agtcgctgga acagtttgta ctgcttgatg aagattagga tcaaaggctt ctcctttagc
    27301 agggattttt tcaattcctt cttcttccag tgcgttacgc aaactttcca agaccatttc
    27361 cacgcctttt ttcaaacctg ccccttgatc atctgacact tctgtggcta atgcacgttc
    27421 caggttgtca attgatggaa gtaatttttt ggctaaatct tgtgaacggt atttttgtaa
    27481 ttgctcacgc tcattttttc ctcgatttgc catatttgcg atttcagcac gagcccgcaa
    27541 gtatttatct tccatttctt ctaactcagc ttttaatttc gctgtttcga attcttccgc
    27601 ttcagcttct gaaatacccg aatcttctgc agcttcgaca tcgatttccg gttctggctg
    27661 agcatctgtc atttctttat ctagttcttc ttgattttct ttcacgatac agtcttcctt
    27721 tcattattca gtcagctgtt tgattgctct tactaagaaa gagagaacga tcagctgcaa
    27781 atagcttcgt tattcacatt acgagtttga caagtcaagc gaacggtagt aatcagcaag
    27841 tttagctgct agttctcttc gataaacatc gactagaccg aacatccgag aataaggcat
    27901 actagtaggc cctaacaagg ctattgtacc tcttccatga ccatctatct cgtaacttgc
    27961 ttgaatcata ctcatattct gcaataaatc attgcctaat tcagcaccaa tcttgatatg
    28021 aatattgcta tccatcggag tgatcatttg tgtaagtccg tctgagtctt tcataaaaga
    28081 aaacatcgat ttgaactgat caagatcttg acggggctca taatccaaga gattcatttg
    28141 tccactgaca taaaccttat cttcaaaaac atgaccaaga acggtgtcaa ataactgaga
    28201 catcccttct gtcgtttgga aatatttatg aagaatcatc ggaatctccg tacgaagttt
    28261 atggtacacc gtcatcagag gatctccgac tagacggtcg tttacaatct gtaccatttt
    28321 ttctagttcc tgacttccca tatattcggg aagagtgaac acttggcttt ctacattccc
    28381 catatctgtt acgacgatag caataatctg tcgattattc aagggtacga tacgaaagcc
    28441 agtcagtcgg cggtctttta tttcaggtcc caatgaaaaa gtcgtatagc ttgtcagctc
    28501 agataatatc tcagcagatt gcttaataat ctcattgatt tcatgaaatt ctctgcctag
    28561 agactgacga atcagcagca aatcatcttc tgctacgcga gcaggtttta acaaatgatc
    28621 cacgtaataa cgatagccta aagcagatgg aatccgccca gaagaagagt gagtcttcaa
    28681 cagcaatcct tcatcttcta atgctttcat atcattgcga atcgttgctg agctggcctt
    28741 gactccctca gacatcaatg ttttggaacc aacgggcacg ccactactcg tatagtgttg
    28801 gatgatcaga cgtaaaatgt cgttttgtcg ctttgttaac atcttcctca cctctcatta
    28861 gcactcatat attctaagtg ctaatccact tataaatata gcaagaagcc cttctcctgt
    28921 caagagaaag actccatttt ttagcactct aaacacaaga gtgctaattc taaataattg
    28981 atgtaaatcc agttatatca acgtttcaat agtcctttat tgtatttttg aacttttttt
    29041 atttaaattc agataaaaaa caaatattct ttaaactatt tttcaaacaa aaagcgctca
    29101 aacacattgt tccccaaaaa ggtccctctt ggtgtcaaat aaacacggtc ttcttcatta
    29161 acaagtaacc cttcttgctc taattccctt agcacatcac cgtacaccga ttcaattgtt
    29221 ttttgatagc gatcatagaa atgtttttta gtaatccctg tttttttctt agtcctaaga
    29281 acatttcttc ttctatttga ttttttcgtg tcaatttttc ttcttccaat accgggcgtt
    29341 catttgctcg taatgggcgt aaatagtgtt ggattggtcc tttgttgcgg taacgaatat
    29401 ctccaagata accgctagca ccagctccaa acccaaaata gtggtcattg ttccagtaca
    29461 tgaggttatg ttgagattca tgtccggaga gcccaaagtt acttatttca tattggtgac
    29521 gtccatgctt ttccattgct tcaatcgtct cttcaaacat tctggtttcc gtttcctgat
    29581 caggcagttc gagtcttcct tgtcgtaccc agttcatgaa cattgttttg ttttcgagga
    29641 tcaatgagta caaagaatag tgaggcagat ccaaagccaa agctttttcc aaagtatcca
    29701 gatatccttc tagtgtttgt cccggtaatg cataaatcaa atcgatgctt acattggtaa
    29761 aattttctgc ttctaaaaat tgcatagttt gatacacatc ttctgcggtg tgtttacgtc
    29821 caattttttt caataagcga ttatcaaatg tctgcactcc catggataaa cgattgacgc
    29881 catagttttt cattacttga agtttttcac gggtcaaatc acctggattc gcttctacag
    29941 taaactcatt accattttga aaaggcagga tctctctagc acctgataac agtcgatcaa
    30001 gttgtttagc agataaagaa gttggtgtcc cgccccctac gtaaagtgtt tctaaattcg
    30061 ctgtcggatg actttctagc attattttca tttcattcag cagcatttcc acatactcat
    30121 ctactggctg cccttctaaa aaaactttat taaaatcaca gtaatagcag atatgctcgc
    30181 aaaatgggat atgaatgtac gcagaaacct tgttttctgc gggatttatt gtttctatca
    30241 ttgaaattct ttctccttac gtcgaaaagt cgtgcctgtt ttcgaccttc ttaaaatcgc
    30301 gttcaagcac caactcattg aaataagccg catatttaga atcaaggaaa cctagctcta
    30361 aaaatgcttg cttattgtca tcggagctac acggtgcttt tacagcctct cgataaacgg
    30421 taatcgcaaa gctgaccttc ggcattaagt caaaatctgc aaaaatatga aaagctattt
    30481 tcacagattc ctccttaagt gctcagacca caacgctttg cttacaacct ctcatatacg
    30541 catactaaac gtatttggcg aacaaatcca ctaaaaaatc caagaatcga cttcttggat
    30601 gattttttct ttcattaaac tggttaccta gttatatatc tctagggttg ttttcatgtc
    30661 tgagtgcccg atatgattta tttttcgttt ctataattac tttttgcctt ccagtttctt
    30721 ttaatattgt actcaagcaa gtgggaattg gttcttttgt catccatgta tgcaaaatgt
    30781 tataatgctg gtaaacaaaa atgattacct gtcattttta tttagttcgt atttaattaa
    30841 gttgactatc tgtatactct gtctaaaact taagaattgt tgttttcgct gtcgctaccc
    30901 aattttaatg aatgtctgta ggttaaaact gttgtccttg ttatagatag taaaggagag
    30961 cttgaaaatg aaaactgcga ttacgtttct attagaggaa tatgccgatt gggaaggtgc
    31021 ttatattact agcacactaa accaaaatga gaaatggcaa aacaaaactg cttctatcca
    31081 atcagaggtc acttccattg gaggattaaa aacaaaaatc gattacttaa tcgaacaaat
    31141 acctgaaaaa gttgaccttt ttattatgat cggtggcaat tcatgggaca taaaaaatca
    31201 tcatttatat caaataatcg ataaattgtt aaaaacagac gtaccagtag ctgctatttg
    31261 tggggcagtt gattatttag ctcagagcgg attattgcaa ggttacaaac acaccggaaa
    31321 tgcgcaattt ccttggttag aatcggaaaa ttatcagaat aaagaagatt ttatagaaca
    31381 acaagctgtg aaagatcgta atttgattac tgcgaatgga acagctccta tagaattcac
    31441 agacttgatt cttcaagcag tccattttga aacagaagaa ataagagaaa aaacgattcg
    31501 tctatacaaa cttggattct atgattacta taaaaagtac ggagatcctt tctcctaatc
    31561 attctcttca attaaatact ccttatcaat agtgtgacaa gtaattttac tgatgattat
    31621 ttgtcacact ttttctgaca tttatcaaag aagatacact ctatttatat tcatagacaa
    31681 ggttttacgg attcaaaaat tcaggattat gctatactgg tattaaaaaa ataatgaggt
    31741 attttatatg aaaaagttag gttttatttt attgttggtc tctttattcc ttgtaggatg
    31801 tacgtctcct agtaaagaaa atagtgatcc atctgcgacc acagacaaaa gttcaatcag
    31861 acaaaccagt tcagctgaaa aatcaagtac tcagaaatca gcttctactg aaacgaatac
    31921 atcttcaaca agcagtaaag tctcagagcc caatacttct tctacatcta gtagtacagt
    31981 tgagacaaat atttcttctt caacaataga cacaacctcc tcacagtctt ctcagtcaat
    32041 agatccgtta gcaggatatt ctgatctaca aattgagtac gcacgtgttt ggctagctat
    32101 tagaggtaat acttttagag atacatcggg tgatttcgaa ttacatgtta ttcattatcc
    32161 tgcaggaaca cctatcgccc cttatgatgc agggagtgca gtctatccga aagatgtggt
    32221 tatgctcact gggaaataca gttaccaggg agttttagtg tattcaagta accatgacgg
    32281 gacaatcact agttatccag ttccttcaca ttggcaaatg cctgcagatc aaacatctta
    32341 tccagcgttc attagagaaa caactcaaga aatcattgat aatgcatctg tagtagctat
    32401 tcctacagga aatcccaatg acgtgaaaca gttaatcgat gtgacagtta tagataatta
    32461 gactttctaa tatgttatac aaaaagaagc tgacagc
//
LOCUS       DADLIO010000026        32322 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.026, whole genome shotgun sequence.
ACCESSION   DADLIO010000026 DADLIO010000000
VERSION     DADLIO010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32322
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.026"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            55..801
                     /gene="truA"
                     /locus_tag="JOX41_001367"
     CDS             55..801
                     /gene="truA"
                     /locus_tag="JOX41_001367"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAY6449119.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(1256..3925)
                     /locus_tag="JOX41_001368"
     CDS             complement(1256..3925)
                     /locus_tag="JOX41_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HAY6449120.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFFYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(4163..4351)
                     /locus_tag="JOX41_001369"
     CDS             complement(4163..4351)
                     /locus_tag="JOX41_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HAY6449121.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            4621..4983
                     /locus_tag="JOX41_001370"
     CDS             4621..4983
                     /locus_tag="JOX41_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAY6449122.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            5035..6717
                     /locus_tag="JOX41_001371"
     CDS             5035..6717
                     /locus_tag="JOX41_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HAY6449123.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            6834..8870
                     /gene="recG"
                     /locus_tag="JOX41_001372"
     CDS             6834..8870
                     /gene="recG"
                     /locus_tag="JOX41_001372"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HAY6449124.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            8919..9920
                     /gene="plsX"
                     /locus_tag="JOX41_001373"
     CDS             8919..9920
                     /gene="plsX"
                     /locus_tag="JOX41_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HAY6449125.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            10042..10284
                     /gene="acpP"
                     /locus_tag="JOX41_001374"
     CDS             10042..10284
                     /gene="acpP"
                     /locus_tag="JOX41_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAY6449126.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            10552..11556
                     /locus_tag="JOX41_001375"
     CDS             10552..11556
                     /locus_tag="JOX41_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6449127.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            11557..12501
                     /locus_tag="JOX41_001376"
     CDS             11557..12501
                     /locus_tag="JOX41_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6449128.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            12501..13463
                     /locus_tag="JOX41_001377"
     CDS             12501..13463
                     /locus_tag="JOX41_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAY6449129.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            13490..14404
                     /locus_tag="JOX41_001378"
     CDS             13490..14404
                     /locus_tag="JOX41_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAY6449130.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            14430..16211
                     /locus_tag="JOX41_001379"
     CDS             14430..16211
                     /locus_tag="JOX41_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HAY6449131.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            16559..17245
                     /locus_tag="JOX41_001380"
     CDS             16559..17245
                     /locus_tag="JOX41_001380"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HAY6449132.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            17265..20846
                     /gene="smc"
                     /locus_tag="JOX41_001381"
     CDS             17265..20846
                     /gene="smc"
                     /locus_tag="JOX41_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HAY6449133.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            20855..21664
                     /locus_tag="JOX41_001382"
     CDS             20855..21664
                     /locus_tag="JOX41_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAY6449134.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            21675..22673
                     /gene="ftsY"
                     /locus_tag="JOX41_001383"
     CDS             21675..22673
                     /gene="ftsY"
                     /locus_tag="JOX41_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HAY6449135.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            22860..25127
                     /gene="gshAB"
                     /locus_tag="JOX41_001384"
     CDS             22860..25127
                     /gene="gshAB"
                     /locus_tag="JOX41_001384"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HAY6449136.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(25216..25668)
                     /locus_tag="JOX41_001385"
     CDS             complement(25216..25668)
                     /locus_tag="JOX41_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HAY6449137.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            25818..26768
                     /locus_tag="JOX41_001386"
     CDS             25818..26768
                     /locus_tag="JOX41_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HAY6449138.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            26761..27720
                     /locus_tag="JOX41_001387"
     CDS             26761..27720
                     /locus_tag="JOX41_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HAY6449139.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            27717..28472
                     /locus_tag="JOX41_001388"
     CDS             27717..28472
                     /locus_tag="JOX41_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAY6449140.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHIGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            28495..29448
                     /locus_tag="JOX41_001389"
     CDS             28495..29448
                     /locus_tag="JOX41_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HAY6449141.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(30092..30388)
                     /locus_tag="JOX41_001390"
     CDS             complement(30092..30388)
                     /locus_tag="JOX41_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HAY6449142.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            30743..31099
                     /locus_tag="JOX41_001391"
     CDS             30743..31099
                     /locus_tag="JOX41_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAY6449143.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            31109..32008
                     /locus_tag="JOX41_001392"
     CDS             31109..32008
                     /locus_tag="JOX41_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HAY6449144.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
BASE COUNT        10708 a         5732 c         6906 g         8976 t
ORIGIN      
        1 ttatagaaaa atcattattc cagataacct tttaggaaca aaggagagaa aaacatggta
       61 cgttacaaag caatcattgc gtacgacgga acaaatttta atggattcca aaaacagcca
      121 aatgggcgta ctgttcaaga agaagtagaa aaaacattac aaaaaatggc aaatggaaaa
      181 gaaatcacgg tctttggttc gggaaggaca gatgccggag tacatgcgat cgggcaagta
      241 atccattttg attatccaga ggagcgtccg ttagaacgaa tgcgtttcgc gctagatacc
      301 cagtcaccag aggatattgc tgtaagacaa gtagaaattg tttcagaaga cttccacgca
      361 agatatttgg tcaaagaaaa gacgtatcaa tttcgagtgg atatagggaa accacgcagt
      421 ccttttcgac gccattatgc aagttatttt ccttacccac ttgatttgga aaaaattcag
      481 cgggcgcttc ctgatttatt agggactcac gatttcacct ctttttgtgc atcaggaagc
      541 tcgatagagg ataaaatacg tacgatctac gaggctaaga tggaggtaaa tgaaacaaaa
      601 gacgaattgt tgtttacatt taggggaaat ggcttcttgt ataagatgat acggatctta
      661 gtaggaacgc ttttgaaaat tggcaatggc cgattgcctg aagatagtat cccagatatt
      721 attgcgaaaa aagatcgtaa tgcagcagga cctacagcac accctgaagg actttatttg
      781 tatgaagtga aatatgaata agaggttatg atagaagtgg tcagcttcaa gaaataagaa
      841 ggtatttacg aaaattactt ctcaaaattt tgcaaaattt cggcttattt tcgaagaagc
      901 tacttctgga acaccgttta aggaagaggt cgtgaaatca gcgttttgac ctgagtatta
      961 gagaaacaaa cgggaaaata gctcctcata ttttgccgtt tgttgagcta ataccgaagg
     1021 tcagctgatt gaacaccgtt taagaaagag gtcgtgagcc tgtcatttaa ctctgagtca
     1081 caaagagcaa tttcaaaaaa cagcttctca tctttgatga atatcgtgac ttgtggacga
     1141 ggcgttgata agtgaatcat ctttttgtta cctatttttt ctgtaaccaa aaaacgatgg
     1201 aacgttgttt tgattgccct tggtgcggac agtctgaaca ggttccatcg tttctttatt
     1261 ttctacgtct tcttctgtgt gtgtttcgtg gttgttcttc tattgctgga tcaatcgtgc
     1321 cataaaaggg gcgattgcgg tcaaggtacc agacataaag aataaacaat gcaatacata
     1381 ggacaaaaag gattgcacct atcgtaaatc cttcaggcaa gtaactgaaa gtgacagtat
     1441 gtttacctgc tggaactttt atcatcaaga atgcgtcttt gaaattgctg accttgactg
     1501 gtttcccatc aattttagct ttccatcctt tgtcataagg aatagttgtc accaacatgg
     1561 aatcttcagc ggtatttaca gtcccagaag cttttctgcc agtggcttcc atttcgacac
     1621 ctttttcttt gatctgattc attgcggctt gataggctac aacatctaga ccaacgactt
     1681 taggctccat gaaacttatt tctttcgtcc cataaaaact tgcagtaaat gtcactgttg
     1741 tctcttgagg ataatagcca agatcatagt attgaccaga aatgttgatt tgcgtttttc
     1801 gcgatgtacc attgacagtg atcgtcgcac tagaactttc taattgcgca aaattggttg
     1861 ggaacaaact taagtaagct tgtgtatttg caggcacatg gacttcccaa gtgagctctt
     1921 ttggctggtt atctgctgtt tctgagtaag tgacgccagt cgttgtcttt gtgatcgtcg
     1981 tattcaactg attcttcaaa gtaggtgtat agaatgtaaa atactgttca tttagaccag
     2041 acaatgtatt gatcaagttt gtctgactgg tcaaattatc tgtcactggc tgctcaacat
     2101 cattaacgga caacggtgca gtaaatgcta gtggcaatgc attgacattc tgatacagtg
     2161 tatagtcgcc gctttgacca gcttggcgga agccatattt actgaacgtg ctttcgtttt
     2221 tagaaatgtt atatttgatt cctgtaaacc catccatcag caaagtatta ttgttataac
     2281 ggatattcaa atttgtccct cttgaacgga aacctaattt atccaggtaa gaggaagaat
     2341 tacgatttct tatagaagaa aacaaactga taccactgta accatagttg atcgaatcgt
     2401 ttgcagatac tggatccaga ttttccaagc ggtaaaacga gtcggaatct ttttttgttt
     2461 catttacaag agctttcaag tcaggataag gatcagtata taaactgcgg gaagcataat
     2521 tccaatcatc aagaatgcca tggatcatac tgttcgtatt gaccagtgct tcagcagaca
     2581 tgatcaataa taacaatata ctcagatgat tgaatgaaag ttttttatgc tgataaaatc
     2641 ccacagcaaa agcataaatc cctaagaaaa ccactgtcaa tacaaaggaa gtcatcgtca
     2701 cataggtgta gcttccttca ggtttgatgc cccatgccac cgcaaagaga gcagctacga
     2761 ccaaaatgat tcctaacaac agcccacgat cgtcttgttc tatcttttcc catccttttc
     2821 ctgcaagcag gagcactaag aaagagaaca gataggcata acggaataaa aacatattcg
     2881 gtgcatgcat accatgccag aacaaattca atggaacaag ataaaaactt gcgataagta
     2941 tggcgaaaag actgccgtac aaaaatttat ttttcaacgg tactttccga ctggcaaaat
     3001 aaaacagaca gaggactaat ggtagcagac ctgcgtaaac gaacggaatc gatccgtatt
     3061 ttgtcgtgtc ataaacacca atcatatttt tcatgattag atccagataa gaagtcgctt
     3121 ctgttttcaa cgtagtgatc tgactcagtg cctcgccatt tgaccgaaga tccagcactg
     3181 ctggcaatac aatgatcatt gaagcgccgc ctgccagtaa agaagtgata ccataaggaa
     3241 caatcgtttt tttatattct gaccagtttg tcaatagacg ggcgataaaa tataagaaag
     3301 aaaatacgcc aatcataaaa cccatataaa aactggataa aaacaagagt aaataactga
     3361 taaataaaag tttcggccgt ttaagatcca taacacgatg aatccccaaa atcactaatg
     3421 gaagataaaa aaatgcatcc agccacatga tgatctccga atgtgcagtg ataaatgaga
     3481 tcaatgcgta actgacgcta agtgcaacat gcccccagcg aggaatcttg aacgtacgtg
     3541 caagaaacca aaaagccaat ccggcacagc cgaccttaag caaagtcaga acatacagtg
     3601 catctggcat catctggttt ggaaaaaaga acaccagtgg cgtgaagatc ccgcctagat
     3661 agtaagaaat taaagataaa taattcaatc ctagagaagc attccatgta taaaaaatac
     3721 tttgctttcc aagaagaaca tttcggaagc tggcatgaaa attagaaaac tgtgaaaagg
     3781 catcacttgc caaaatactt ctgctgcttc caggatagat tccgatactt agataaacaa
     3841 gtgctaaaat caaaaacgga atcaggaaac tagctgctgc gtagcgtccg ttttctctaa
     3901 agaatgactt taaatttttt ttcatattta ttttccacca aatttctatg aagttgtatt
     3961 cagtttatca tatccttgtt tttctctgct taaaaagagt ctagttttca caaaaaaata
     4021 aaatttagaa taaataactt cataatttgt tcgtataaca aaaataaacg caaaaaaagg
     4081 gtaggaatca aaagtcccac ccttaaaaat ttttattaaa taaaaaaccg ttcactatct
     4141 gaacggtcca agtatcattc aattaaacgc gttcaacttt tcctgatttc aaagcacgag
     4201 ttgacaccca aactttttta ggttttccgt cgaccataac gcgaactttt tgtaagttag
     4261 gtttaacagt acgttttgtt gagttcatag cgtgtgaacg gttgtttcca ctttttgtct
     4321 tgcgacctgt aaagtaacaa acttttgcca tggtaatttc ctcctttgcc ttgatttgga
     4381 gcaatagaat aattcagctc ataccagact aacatatcat atagaatggg aatttgcaag
     4441 tacattttca tagatacaat tgacaattga gaagaataat tgtaaattaa acaaggttat
     4501 acctgaaatt ttgcaaggtt tttgagtact ttgggtaact gccttttatt tcaagttgcg
     4561 ctatgataaa atatgataga agaaaaatgg gagtttttta cccgttaagg aggctcattc
     4621 atggctgtaa aaattcaaac gtcagctgga accattgaaa ttaccaatga tgtaattgca
     4681 acagttgttg gtggcgccgc gacagatgtg ttcggtgttg taggaatggc cagcaaaaat
     4741 caaattaaag ataatattac tgagattttg cgtaaagaaa attactcaag aggagtagtt
     4801 gtccgccaag aagataatgg tattgctgta gatgtttata cgattatcag ctatggtacg
     4861 aaaatctctg aagtttcccg caacgtccaa gaaaaagtga aatacaatct agaggcatta
     4921 ttaggcgtaa ctgccaattc agttaatgtc tttgtacaag gtgttcgtgt actgccagac
     4981 taggcaggag actggctggt aactcagcag tcgatctgaa ggaggattat ctaggtgagt
     5041 gtaacagaaa taagtgcaag ccagttccag gaaatggtcc aggcaggtgc gaatcgtctg
     5101 caagtaaatg cagaatacgt caattcatta aatgtattcc ctgtgccaga tggcgatacg
     5161 ggaacaaata tgaatctatc tatgactagt ggagctaagg cagtagtaga ttcaacctca
     5221 gaaaaagtag gagaattagc agcaatgctt tcaaaaggat tgctgatggg tgcgcgcgga
     5281 aattccggcg ttattttgtc tcaattgttt cgtggatttt ctaagcaaat tccagatgtt
     5341 gtctcattaa atgcttctga tcttgctgca gccttcactc atggagttga aactgcgtat
     5401 aaagcagtaa tgaaaccagt agaaggaacg attttgacag tagctagaga agcagcgaaa
     5461 gctggagaaa agaaagcaaa aagtactgat gatgtcgttg aagtaatgac agctgttgta
     5521 aaaggagcaa agcgtgcttt agctaaaact ccagacttgc ttccagtcct aaaagaagtc
     5581 ggtgtcgtag acagtggagg gcaaggactg ctgtttgttt atgagggctt tttaagtgca
     5641 ttgaatggag aattccaagc ggatgaaaca tatgaacctt ctccagcaga aatggatgat
     5701 atggtcaatg cagaacatca tcgcagtgtc caaggtcaaa tggcgacaga agatatccat
     5761 tttggttact gtacagaaat catggtaaaa atcggagaag gacctacagt cgatagtaca
     5821 ttcgattacg aagaattccg taactattta gatggtatag gagattcttt acttgtggtc
     5881 aatgatgacg agatcatcaa agtccacgtg catacagaaa acccaggaga agtcttgaat
     5941 tatggacaaa aattcggttc attagtcaaa atcaaagtcg acaacatgcg cttgcagcat
     6001 gagacgattt tggaacacga tgaagaagtg aacgagtttg cgaaaaaaga aataccacgt
     6061 atcccgtatg gtatcgtagc gatcgctgct ggtaaaggcg tccaagagct gtttgaaagt
     6121 ttaggcgcta attatgttat cagtggtgga caaacaatga atccaagtac ggaagacatt
     6181 gttaaagcga ttcaagaagt aaacgcagat aaagtgattg tcttgccaaa caataagaac
     6241 atcttcatgg cagctgatca agcagcagaa gtagcagata tcccagtagc agttgttcct
     6301 tcaagaacga tttcccaagg attgacagct atgctttcat tcaatgatca agcttcttta
     6361 gaagaaaaca aagaaacgat gacagaaatg ttgtctagcg ttgtgagcgg tcaagtcact
     6421 cacgcgatca gagatacctc aattgacggt gtagagatca aagaaggaga ctttttgggc
     6481 atgatcgatg gaaaaatcct gatctctaac ccagatatca cagcaacagc gttaagtaca
     6541 ctagaacaaa tgatcaatga ggacacagag atcgtaacga tcttggcagg tgatgaagga
     6601 acagttgaac aagcaaatga atttgctgag aaactaacag aaaaacatcc tgatttggaa
     6661 atcgagatcc accaaggaga tcagcctgtc tatccttatc tattttctgc tgaataattt
     6721 ctgtgtcaga atatctttct aacacagtat tcattcataa aaggccttcg gttagtgatc
     6781 aggtatgatc gctgaccaag tccttttttt gttaaaggag ggaggaaaaa tttatgcgtt
     6841 ctttagatga tccaatcact atgctggcag gagtcggaga aaaaagagca gctagtcttg
     6901 ccagcttggg catccaaacg attgaagact tactgactta ttatcctttt cgctacgaag
     6961 atattcagga aagaaatcta aacgagatcc aggatcaaga aaaggttact ttgaaaggaa
     7021 tcgtagtctc gcctcctgtg atgaatcgat ttggttataa aaaaagccga ttgcaatttc
     7081 gtatgatgca agaacatgat gtgttcaacg tttctttttt taatcaacct tatctaaaag
     7141 aaaaagtcat tttatcggag gaaatcgccg tatacggtaa atgggatgca aagcgtaaag
     7201 ccttgaacgg gatgaagatt ttaggttctc aaacaatgga tgacttttcg ccgatatatc
     7261 acgtcaacaa atcaattcgt caaacgacat tagttgatct aatcaaaaaa gggtttcaag
     7321 aatacggcac attgattgaa gaaaatctgc caaacaacct tgtggagaaa tatcgactgc
     7381 ttgaccgagc ttctgctgta agaagtatgc attttccaaa agaccacgaa gaaaaccatc
     7441 aagccaaacg acgtgtcgtt tttgaagagt tctttttatt tcaaatgcgt cttcaaggat
     7501 tgaaaaaagc agaaaaagca gaaacgaatg gtttggagat cctttatgat gtccaaaaat
     7561 tgaaacaatt tactcaaaag ctaccttttg aactgacaaa tgcacaaaaa cgtgtaacga
     7621 atgaaatctg tcgggatctt cgcagtccgc agcatatgca gcgacttttg cagggagatg
     7681 taggtagcgg aaaaacagtg gttgccgcga ttgcgttata cgctaccgtt acagcaggtt
     7741 tccaaggtgc gttgatggtg cctacagaaa tcttggcaca acaacatatg gaaagcttgc
     7801 aacagctgtt tgatcccaat gaagtaacca tcgcattgat tacggggtca acgaaagcaa
     7861 aagaacgacg tgagctcctt gaaaaactag agcaagggga aattaacgtc gtgatcggca
     7921 cacatgcatt gatccaagat ggagtcgaat ttcagaattt aggtctagtt attacggatg
     7981 agcagcaccg ttttggcgtg aaccagcgga aagtacttcg tgaaaaaggc tggcgaccag
     8041 atgtcttatt tatgacagcg actccgattc ctagaacatt agctattaca gcatatggtg
     8101 agatggatgt atctatcatt gatgaacttc cagctggacg tatcccgatc gaaacacgct
     8161 gggtaagaac acctcaattg gacagtgtac tggattggac gaaaaaagaa ctggcaagag
     8221 gacatcaaat gtatgtcatc tgtccgctga ttgaagaatc agaagcatta gatgtaaaaa
     8281 atgcagtgga aatctatgaa aaacttcgtg aactatttgc accaaaatat gaagttggct
     8341 tgttacatgg taaaatgaag aatcaggaaa aagaagtaat catggaagcc ttcaaagaca
     8401 accagatgca gatattagtt tcgactactg taattgaagt aggggtaaac gtgccgaacg
     8461 cgaccgtcat gctgatcatg gatgcggatc gatttggatt ggcacagctg caccaacttc
     8521 gtggacgtgt tggacgcgga agtgatgctt cctactgtat cttagttgct aatcctaaaa
     8581 atgaactagg tgtggaacgg atgaaaatca tgacagagac caccaatggt tttgtactaa
     8641 gcgaaaaaga tctggaatta cgtggtcctg gtgaagtatt tggcttccgt caatctggtc
     8701 tgcctcaatt tgcgattgct gacttggtga cggatggaaa tgttttggag gtagccagag
     8761 aagaggctgc agccctttgg caaataaagg attggcagat gcttcctgag tatcagcctt
     8821 tagcgcaaag cctccaaata gaaaatcagg ataatcgtta tttcgattag cagactgtgc
     8881 tatactttat actgatgacg gaaaaaggag tggaaacaat gaaaattgcc gtagatgcaa
     8941 tgggcggaga tcacgcacct caagcaattg tagaaggcgt ggctttagcg cagcaagatt
     9001 ttccagaagt agaattctta ctttacggaa aagaagcaga aatcaagaaa tacttaacaa
     9061 atgaaaaaaa catcacgatt atccatacag acgaaaaaat caatagtgat gatgagccag
     9121 taaaagcaat tcgacgaaaa aagactgcat caatggtcct tgctgcacaa gcagtgaaaa
     9181 acggtgaagc agatgctgta ttttcagcag ggaatacagg cgcgctacta gcagcagggt
     9241 tgttcatcgt aggacgtatc aaaaatatcg aacgccctgg cttgatgtct accttgccag
     9301 tagtagggaa agaaggtgcc ggtttcgata tgctggatct tggcgctaac gcagaaaaca
     9361 aaccagaaca tttgttgcaa tacggtattt taggttcttt ttatgcacgt aaagtccgag
     9421 gtatcggacg tcctcgtgtc gcactcttaa acaacggaac agaagcaaca aaaggtagtg
     9481 aagtgacgaa aaaagcctat gaactccttc agaatgaaac aagcttgaat tttattggaa
     9541 acgtagaagc tcgtgagcta ctcaatggtg tggctgatgt agtggtcaca gatggattta
     9601 caggcaacgc tgttttgaaa tctattgaag gaacagcaat gaatatgatg aatctattaa
     9661 aatctgctat tctaaatgaa gggatcaaag gaaaaatggg cgctatgctt ttaaaagacg
     9721 gcttacgttc tttgaaagca gaaatggatt attccaaaca tggcggtgcc gttttgtttg
     9781 gcttgaaagc accagtcatt aaaactcatg gagcaacagg ccccgatgct gttcgctata
     9841 cgatccgcca aatccacaca atgcttgaga cagatgtagt tggacaatta gtcgaacaat
     9901 ttgaaaaaag cgaagaatag tatttggata tctgaagcga tccgttccat tgaaaaaaag
     9961 gtggacattc ctgaaaaatg ccagtaaaat tagccatggt gtaggtaatt gacaagtgta
    10021 tgattcttgg aggtgaaaaa gttgactcgc gaagaagtat ttaacaaagt agcgaaaatt
    10081 atttcaaatc attttgagat agataccgat aaagtgacgg atgaattgaa catcaaagat
    10141 gatttaaaag ctgattcaat tagtattatg gaattcgttt tagagcttga agatgaattc
    10201 ggtacggaaa tttcagatga agacgctgaa caaattgaaa cagtcggtgg cgcagtagat
    10261 tatatcagca gccatcttaa ataatttcaa ataaaagcaa agaaggataa aaagctgcat
    10321 gcagcttttt atccttcttt ttttaatctt tttgacacgt aaaagtcatt tttctgataa
    10381 ttctggcgat aaacagaaat tatgttgcaa agtaaagcgg ttttctatat aattattaat
    10441 aattcattac acaaagataa gaataacctt tgttataaaa cgatttattc tgtgtaatgt
    10501 ccttttttat taagaaaaac ttccatttag gaagcagaga ggggtattcg attgtccgat
    10561 aaccaattat tagaagttca gaacctacat acaggattcc gactcaaaga tgactattac
    10621 gatgcagtag atgacgtttc atttacttta gacaaaaacg agattttagc aatcgttggg
    10681 gaatctgggt gcgggaaaag taccttggct actacgatta tgggattact tgatcctaat
    10741 aacacaaaaa ttacaggtga gattttatat aacgatctga atttaatcga cctgaacgaa
    10801 acgctctata ataaaatccg cggaaatgat atcggaatga ttttccaaga tccgttgtct
    10861 gcattaaatc ctctcatgag aatcgaagac cagatcaaag aaggactttc ctatcacaca
    10921 aagatgaatg cagaacagcg tcaagctcgt gcactagaat tgctagaaca agtagggatt
    10981 cctaatcctg cgagagttgg acgccaatat ccccatgaac tatcaggcgg tatgagacaa
    11041 cgtgtcatca tcgcaatcgc aatcgcctgc aaacctccaa tcgtcattgc agatgaaccg
    11101 acgacagccc tagatgtaac catccaagca cagattcttg atttactgaa agaccttcag
    11161 gaagaaacaa aaacagggat catcttgatc actcatgact taggagtcgt agcagaaatg
    11221 gctgatcgag tggcagtgat gtatggcgga cagttcgttg aagtagcagg tgtaaaagaa
    11281 ctgtttgatc atcctaagca tccttataca cgctctttac tgaactctat accacaagaa
    11341 ggaaatcatg atgcagaact ccatgtgatc gaaggtgtcg ttccttctct gaaaaacatg
    11401 cctcgtaaag gttgtcggtt tgcaccacgt attccatgga taccagcaag cgatcatgaa
    11461 gaagagccta tccttcatga agtcgcaccg aaccacttgg tacgttgctc ctgctataag
    11521 catttccact ttagagacga aaaaggagag gtgtagatga cagaattaat cacaatcaaa
    11581 gacctgaaag ttcattaccc tattcgcagt ggattcttca atcgagtaac ggatcatgta
    11641 tatgctgtag atggtgtgga ttttattatc gaaaaaggaa agacatatgg tttagtggga
    11701 gagtctggct ctggaaaatc tactacggga aaagccgttg tgggattaga aaaggtaaca
    11761 gccggacaaa tcatgtatga aggaaaagat gtaacgaagc gaagcaaccg caaaaaaatg
    11821 ggttataaca aggatgtgca gatgatcttc caagattcaa tgtccagttt gaatcctaaa
    11881 aagcgagtgt tggatatcat tgctgaaccc atccgaaatt ttgaacggtt aagcgatcaa
    11941 gaagaaaaga aaaaggtaaa aggactgcta gatatcgttg ggatgccgga agatgcgcta
    12001 tataaatatc ctcatgaatt ttcaggcgga caacgtcaac gtctaggagt agcccgtgct
    12061 gttgctacca atccaaaact gatcgtagcc gatgaacctg tatctgctct ggatctatct
    12121 gttcaagcgc aagtattgaa tttcatgaaa cgaatccagc aagaatacgg cctcagctat
    12181 ttattcattt cacatgattt aggtgtagta aaacacatgt gcgacaatat cgcaattatg
    12241 tacaaaggtc gatttgtaga aatcggtaca agagaagaca tttataatga cccgcgacat
    12301 atctatacga aacgtctgct ttcagctatt ccgcaaatcg atgtagaaaa tagggaaagc
    12361 cacaaagaaa atcgacgaag agtagaacaa gagtatatcc aaaaccaaaa agaatactat
    12421 gatgcgactg gtcgagtcta cgatttgcgt acgatcacaa ctacacacaa agtggcgttg
    12481 aaagatggag gtgcaagcta atgtggaaaa cgattctgcg acgtgtttta ttgatgatcc
    12541 cgcaagttat tattttaagt gttctgatct tcttattagc ccaagcgatg ccgggggatc
    12601 catttaccgg tttgatcaat ccaaatcagg atccggcagt gatcgaacag atgcgacaag
    12661 cagctggctt gaatgaccca tggtatgtcc agtacttccg ttggatcgga aatgctttgc
    12721 aaggcgattt tggtcaaagt ttcttataca aacgctctgt tgctgacttg atcggcgaac
    12781 ggatcatcaa cactttatat ctatcgatct tgacagttgt ccttacttat ttgattgctg
    12841 tgcctctggg gatgcttgct ggccggtatc aaaattcaat cttggataag attgtcgtaa
    12901 tctacaactt ctttagtttt gctgttcctt tatttatctt cggcttgatc atgctatttg
    12961 tttttggtta tcgtttaggc tggttcccaa caagtggatc acaaacacta ggtttgcaag
    13021 gtggatttat cactcaatgg atagaccgtt tgaaatatat tctgttacca tcaattaccc
    13081 aagcattttt ggcgactgcc gtcacaatcc aatatctgcg aagtgaagta atcgattcga
    13141 aatcgctcga ttttgtcaga acagcccgtt ccaaaggggt accgacgaat aaagtattca
    13201 gtcgacatat tttccgaaat gcagcgttgc cgatggcttc tcaaatgggg tatgaaatca
    13261 cttcgttgat tgctggttct gtagttatcg aaaagatttt tggttatccg ggagtcggaa
    13321 aactatttat tgattccatc ggccaacggg actataccgt gatcacatcc ttagtattga
    13381 ttttaggaat cgcgacgcta gtggggacat tactttcaga tatcatcatg agtatcgttg
    13441 acccgcgtat tcggattcaa taaaaccaat cagaaaggag aatggatcga tgagtgaaaa
    13501 aaacaataca gcagttcaag aaagtattcc tcctatgggg atacgaatga ttgctcgaga
    13561 atttaaaaaa gataaaattg ctattttttc attaggtttg ctagtggttt tattattagt
    13621 gatctttatc ggtgcgatgc tgaccgatca agacaaagtg atgtatgtta gtatcttcga
    13681 caaatacgct gcaccaggaa cagtttcgac acaaggacaa aagttcattc tgggagcaga
    13741 tgaaggcgga cgtgatgtat taggacaatt gatcataggt gctagaaact ctgttacgat
    13801 cggatttgcg atcacgatcc ttacttcgat catcggggtt ggattaggga tcatctctgg
    13861 ctactacgga gggatcattg acaacatctt gatgcggatc gttgatttta tcatgattct
    13921 accgatcatg ctgatcatta tcgtcttcgt atcgattatt tccagataca atgtctggtc
    13981 ctttatattc atcatgagtg cattttattg ggtagctaaa gcccgattat tccgaagcaa
    14041 gacattatct gaagcaagaa gagattatgt cagtgcctca aaaacaatgg gaaccaatga
    14101 ttttaaaatc atgttccgcg aaatcatgcc gaatctaagt tcattaatca ttactaattt
    14161 gacgatgaac tttgcggcaa acatcggtat cgagacaact ttgactttct taggtttcgg
    14221 cttgccggca aatgtaccta gtttaggtac attgatcggt tatgcaagta acggagaagt
    14281 cttagtgaat cggcaatgga tctggttacc cgcatcaatc cttattttag ttttgatgtt
    14341 gagtatcaat tatgttggac aagcattcaa gcgttctgca gatgcgcgcc aacggttagg
    14401 ctagtataga agcgaagggg gaaataggaa tgaagaaaac gatttttgga tttgcagcgc
    14461 tgatgtctgc tgtcgttctt gcagcatgcg ggggcggagg tacagatacc tctggaaaca
    14521 actctggagg caacggcaat aacaaagagg aattaacttt tccaattgca acaaaaaata
    14581 atgatgatgc aatcgaagac ggcgaattag aagctgcggt cgcaacggac agtcagttta
    14641 aaggattgtt ccagtgggag ttttaccaag attcatatga tgcagctttt atggctcctt
    14701 ctcatgaacc gctatttgca aacgatgacg atttcagaat cacagacgac ggagctgcaa
    14761 cgcttgatct agatgaagat acgaaaaaag cgacaatcaa agtaaaagac aacgtcaaat
    14821 ggtcagatgg tgaagatgta acggcggacg atgtgatttt cccttacgaa atcattggga
    14881 ataaagatta cactggtatc cgttatgacg acactttccg taacatcgta ggtatggaag
    14941 aatatcatga tggaagtgcc gacacaatct ccggaatcaa aaaaatagac gacaaaacag
    15001 ttgaaatcga atataaagaa gtaaacccaa gcatgcttca atcgggtggt ggtatctggt
    15061 catatgcagc accaaaacat acgttagaag gtgtagcaat caaagatatg gaatcaagcg
    15121 atcaagtacg taaaaatcca gtgacttttg gcccttatta catgagtaat atcgttgcag
    15181 gagaatcagt agaatacttg ccaaacgagc actactggaa tggtacgcct aaattgaaaa
    15241 agatcacgat gaaatctgta ccgatggcaa gtgcaactga agcattgaac tctaaattat
    15301 atgatatgat tttccaaatg ccaacagata cttacgatac ctataaagaa attgctggct
    15361 atacaaactt aggccgtgaa caaacttctt atacttatct aggattcaag ttaggtaaat
    15421 ggaatgcaga tacaaagagt gtggaataca atccagattc aaaaatggct gataaatcat
    15481 tacgtcaagc aatgggctat gcattagata ataatgcagt aggtgaacgt ttctatgcag
    15541 gtttgagaag caatgcgact tcattgattc ctccagtatt ccagtcatac catgatgatg
    15601 agatgaaagg attcacacaa gatctagaca aagcgaaaaa actattagat gatgctggct
    15661 acaaagatgt ggatgacgat ggtttaagag aagacaaaga tggaaataaa ctaacaatca
    15721 actttgcttc gatgtccggt ggggaaacag cgcaaccatt ggcagattac tatatccaac
    15781 aatggaaaga aattggtttg gatgtccaat acacaacagg tcgtctgatc gaattcaatt
    15841 ctttctatga taaattagaa aacgatgatc ctgaaattga tgtttaccaa gctgcttgga
    15901 atacaggaac tgatccaaat ccaagtggac tatggggacc aaatgctgcg ttcaactaca
    15961 ctcgttatga atcagaagaa aatacaaaat tgatcaacga tatcagttca agcaaagcat
    16021 ttgatgaaga gtaccaaaaa gaagcatatc aaaaatggca acaatatgca tttgaagaag
    16081 catttgcgat tccaacgttg ttccgtaatg aagtattgcc agtcaacgac cgtgtcaaag
    16141 actgggattg gtcttatgat gtaccaaacc catgggcaaa tgtttctgtt acagcagatt
    16201 cacgttcata atcactaaaa atgaccgaaa aagggcgatg tcctttttcg gttttttgat
    16261 atttttctgt ttatttctct aatattcagg tcaaggcgct gatttcatga cttctccaat
    16321 aaacggtgtt caaagtccag tttctcggta ttaagtcaaa tttatgcaaa aatatggaaa
    16381 gccattttca caaaattttt tcttcatact cgaaactaaa cgaatttttc acaacttctc
    16441 gtcaatcact aggattatta aagctttact taccttttga ccgaaccatt tcaaatttga
    16501 caaaaaacca gtataataag gaagtatcga aaaaatatcc ataaaaggaa tgtggaaaat
    16561 ggacaaccag ctgacaaaag aactaaaaga aaactataac atcgtttttc acgatctaaa
    16621 tttgcttgaa caagctttta cccattcatc ctatgtgaat gagcatcgca atctgcaatt
    16681 atcggataat gagcgacttg aatttttagg agatgccgtt ttagaactga tggtttctca
    16741 gtatttattc cgtttatatc ctcatttgcc agaaggaaaa ttgacaaaaa cacgagctgc
    16801 gatcgttcgc gaagacagct tgtcgaaatt tgccaaagaa tgtcactttg atcaatatgt
    16861 tttgttgggc aagggagaag agaattcagg aggacgtacg cgaccagcat tgctttgcga
    16921 cctattcgaa gcttttttag gcgcgttata tcttgaccag ggattcgaca cgacccatgc
    16981 attcatcgaa aaagtgattt ttcctaaagt caaagcaggt gctttttcac atgagatgga
    17041 tcataaaaca aaactacaag aagtcttgca aaaatcaggt gatgtatcaa tcgaataccg
    17101 attgatcaat gaagaaggtc cagctcatga acgagtattt tggatcgaag tttatgtaga
    17161 tgatcaattg attggcactg gacaagggaa atcgaaaaaa ttagcagaac aagctgcggc
    17221 ggaaaatgca ttggcagcac tgtaaaagta agtgagggaa agctttgtat ttgaaacgaa
    17281 ttgaaatagc cggttttaaa tcatttgcag acaagacagt cattgatttt gaaaatagcg
    17341 tcacagcagt ggttggacca aatggcagcg gaaaaagcaa tattacagag gctatccgct
    17401 gggtattagg agaacaatct gctaaaagtc tgcgaggcgg aaaaatgccg gatatcatct
    17461 ttgccggttc cgatacccgt aagcagctga atattgcaga agtcacagtg attttagaca
    17521 atagtgatca ttatctgcca ttggagtaca atgagatcag tgtaacccgc cgttatcgac
    17581 ggactgggga aagcgagttt ttcatcaata aacaaagctg cagattaaaa gatatccaag
    17641 aattgttctt agattctgga ttaggaaaag aatcgttctc aatcatttct caaggaaaag
    17701 tagaagcgat tttcagtagt aaaccggaag accgtcgtgg gatctttgaa gaagcagctg
    17761 gtgtcttgaa atacaagcag cggaaaaaga aagcagaaca gaagcttttt gaaacagaag
    17821 acaacctcag ccgcgtccaa gacatcatcc acgaattgga agaacagtta actcctttgg
    17881 ccgcccagag tgaggcagca aaggagtttt tacggctaaa agaaacactg actcaaaccg
    17941 atgtctcttt gatggttgct gaaatcaaga cagcaaaaaa agattgggac aacaaacaag
    18001 cacagcttgc gaaattcaat ctagaattag gcaaactatc tgagtcgatc caagaacaag
    18061 aatccatttt ggcgaagcag cgtaaagaaa atgcgcaagc cgatcgtctg atcgaaaaaa
    18121 atcagcaagt attattagat ctttcggaaa aactgaagca gacagaagga caaaaagatg
    18181 ttttgcagga gcggacaaag catacacaaa aaagctcgca agaatatcaa acttcattag
    18241 cagaagcaca aaaaaaggtt aaacattttg aaaagcttca agaaagcttg atgaaagcag
    18301 cagcagaaaa agaaacagag atccaaaaag ctgaagcaaa tctcataaaa acacagcaag
    18361 aattagaaaa ataccaaaaa tcaacgaaag aattattggc agaattaaga gatcaatatg
    18421 ttgatttgat gcaagaacaa gcagctgtag gaaacgaact gaagtatcta gaacgtcaat
    18481 atatacaaga aacagcaaaa agcaagcaga cgttagccaa gcaatcggaa gtagaagcat
    18541 cagtagaccg attgatctta caaaaagaag aattgacaca aaagcaggcg cagctaaaat
    18601 catctttaac tgaaacaaaa gagaagttag aaatgatcca acaaaacggg aaaaagttcc
    18661 aagaagcatt agcaaaagaa cagcctaaaa tgtatcaatt aatgaatcaa gtccagcagc
    18721 tacgtgctcg taagaaaagc cttcaagaaa tccaagaaaa ctattttggt ttttaccaag
    18781 gggttcgatt ggtcttgcag cataaacagc agctttcggg tattgtcgga gcagtggctg
    18841 aactgatcga tgttcctgca gatttcacgt tagctatcga agcagcttta ggtggggcag
    18901 cccagcatgt catcgttgaa aatgaaaaag atgctcggca agccatcacg tatttgaaac
    18961 agcaaagagg aggaagagca acattccttc cactgacgac aatcaaacca agacaattac
    19021 cggctcatat attgacacaa gcagcagctg tagaagggtt tatagggatt gccagtgaac
    19081 aagtcagtta tcccgatcaa atccaaactg tggttcaaaa cctgctagga acgatccttt
    19141 tagccaaaga cttaactagt gccaatgcaa tcgcgcaaac gatccgctat caatatcgag
    19201 tggtttcctt agaaggtgat gtgatgaatg ccggaggatc catgacaggt ggagcgaata
    19261 aacgaggaaa ccaaggcagt ttgtttgtac aaaatcaaga attgaaacag ttgactagtg
    19321 aatttgaaga agcagataaa caactccaag cacaagaaaa aaaagttcag gagctgcaac
    19381 aagaaacagc tcgtttagcc gaagaacaag aagttttgcg tacacgaggc gaacaattac
    19441 gttttgaaga acaagaagcg acaaatcagc tacaaaacat cataaatgaa cttgaacgtt
    19501 ttgaaaaaga aaagcaaatc tcaacttttg agacacgtga actgcagcag tttatcgaag
    19561 attacgaaaa gcaaacgaac gaattgaaag acaaacaaac agatcttgaa tcgcaacgac
    19621 aaaaaatcga cgaagaaatc aaatcgttaa gtcaagaaag cgaccagatg gaagccagaa
    19681 gagcacaagt acaaagtcaa aaagcacaag aacaagcaga tcttgctgtc ttgaaagagc
    19741 agtttaatca tctgcagatc cagctccgcg gtgcccgagt ccaaaaagca gaggcaaccg
    19801 aacgtcaaga agcgatagaa aagcagttgg cgacattgac agcagacttt tctgatcatg
    19861 aagtcacaga agaaagtttg gaaaaacaaa ttaacgaatt atctgctcag cgagaaacat
    19921 taaaagccga gttggcaaaa gccaaagagc agcgagatag aaggcaaaag gagatcgata
    19981 agcttgaagc agtcttggca gagcgtaatc gtgagcaaaa agcacgactg tcggaacaat
    20041 ccaaattaga agtccaaaaa gaccgagctg aaatgatttt agataatcat ttgacctatc
    20101 tgcagtcaga atatcagctg acatttgaga aagcttccca agactatcaa gaaacaaccg
    20161 atatcgaaga cagtagaaca aaggtttcat ccttaaaaga acagattgaa aaactgggac
    20221 cagtaaactt aaattcaatc gaacaatacg aacaagtcag tgaaagacat acattcttag
    20281 caacacagcg agatgatctg ttagcagcga aaaaccaatt gtttgaaacg atggatgaga
    20341 tggatgatga agtgcggaca agattcaaag aagtatttga agctatccgt caagaattca
    20401 aaattgtctt tccaaatatg tttggcggcg gtaaagctga attagtactg acggaaccaa
    20461 ctgatttgct gaaaacaggt attgagattg aagtacaacc tcctggcaaa aaactgcaaa
    20521 gtctaagttt gctttctgga ggagaacgag cacttacagc catcgcgttg ctcttttcca
    20581 ttatccgtgt ctgtcctgtt ccgttttgta tcttagatga ggtagaagca gcgttagatg
    20641 aagccaacgt gaaacgtttt ggtcgttact tgagcgattt ccaagatgac acacaattta
    20701 tcgtagtcac acaccgcaaa ggaacgatgg tcgcagcaga tgtactgtac ggagtgacga
    20761 tgcaggaatc cggtgtatca aaaatcgttt ctgtacggat ggaagatatc aatgaagagg
    20821 cgaaaatcaa cgaaacgaaa gtgtaggaac gaaaatgatc aaattagtag caatcgattt
    20881 ggacggtaca ttattaaatg aacaaaagct gatttcagat gagaataaac aagcattagc
    20941 acaagcaaaa cagcaagggg tcaagatcgt tctatgtaca ggacgcccct tagctgcgat
    21001 ggcgcattat ctgcaagaat taggactggt agatgaaggt gactacagca tcactttcaa
    21061 cggcggtttg gtacaaaaaa atgatactgg tgaaatcatg gaaaagaaag tgatggaagt
    21121 atcagatatc caacgcttat acaaactggc tcagcaattg gatctgccac tagatgtttt
    21181 gtctgacaat gtggttttac agctgcctag tgccccaagg aagcaatcct tgtacaatgt
    21241 gttgaataag ctgctgcaat tccaaccagc ggatataagc gatattacag atgaatttgt
    21301 gcttaataag gcagtaatcg cttatgacca agaagaatta gatcctaaaa tcaaagaaat
    21361 accagcagaa ttccatgaaa tgtatgagat catcaaaaca agaagtatgc ttttggaatt
    21421 tatgccaaaa ggtgttacaa aagcttatgg tatttcttta ttggcaaaag atcttggttt
    21481 gaaacaagaa gaaatcatgg cgatcggtga tgaggaaaat gatttaccga tgatccaata
    21541 tgctggacta ggcgtagcga tggagaatgc tgtgcctttc gtcaaagaag cagcagattt
    21601 cgtgacagcc agcaatgaag aaaatggcgt agccaaagtg atccaaaaat ttgtattaga
    21661 gtagggggag tcaaatggga ttttttgata aaatcaagcg tgcttttact ggcgaagaga
    21721 aaacagaaga agttgaagta caggagaagt acgacaaggg tttagaaaag acgcgtaaaa
    21781 catttggtga acggatgaat gagttgtttg ccaattttcg aacagtcgat gaagactttt
    21841 ttgaagaatt agaagaaaca cttatcggtg cagatgtagg ttttgaaaca gcgatacgaa
    21901 tcaccgaagc attacgtcaa gaagtgaaac tcagaaatgc gaaaaaatcg gcagaagtcc
    21961 aaaatgcgat catcgagaaa cttgtggatc tctatgaagc ggaaggaatc aatgaagtaa
    22021 atgaactaaa tatccaagaa gacggactaa cagttatttt gtttgtcggt gttaatggtg
    22081 tagggaaaac aacaagtatt ggtaaacttg cccatcagtt caaaaacgaa ggtaaaaaag
    22141 tattgatggc agcagcagat accttccgcg ctggagcaat cgaccagtta gttgtctggg
    22201 gcgaacgcgc tggtgttgaa gttgttcgtg gcaatgcagg aggcgatcca gcagctgtcg
    22261 tattcgatgc tttggaaaga gcaaagacag agcaggcaga tgttttacta gttgatactg
    22321 caggccgact gcaaaataaa gtgaacttga tgaacgaatt agaaaaaata aaacgagtaa
    22381 tccagcggga attaccagaa gcaccccaag aaacacttct tgtattagat gcaaccactg
    22441 gtcaaaacgc gatggttcaa gcaaaacaat tcaaagaaac aacagatgtg accggtcttg
    22501 ttttgacaaa attagatggt acagcaaagg gcggtatcgt acttgctatc cgtaatgaat
    22561 tgcatttacc agtgaaattg gtcggtcttg gtgaaggaat cgatgacttg gagccgtttg
    22621 atccaaatga ttttgtcgtt ggattgttca aaggattact aaaagaagaa taacccatgt
    22681 ctaaaaagca ggagctgtga caaaagttgc agctccttgt ttgaatgatt gtttttaaca
    22741 tagctgtgtt tttgatgcct tcatttttat acttatttgt aagcggttct caaacaattt
    22801 cgttcttttt cttagacttt ttgattataa ttagattcat atgaattgga ggtcacttaa
    22861 tgatgaattt taagcaatta ttattgcatg tcaatgcgcg cccttttatc gaccaagctc
    22921 gatttggtat agaacgggaa ggacagcggg ttgatcttgc aggaaatcta gcaaaaaccg
    22981 atcatccagc aatctttggc gatcgatcct atcaccccta tatccaaaca gattttagcg
    23041 aaacacaaac agagatgatc acccctgtta ccgattctat tcccgaatta tttcagtatc
    23101 tcgctgctgt ttatgatgtg actgctcgtt ctataccgaa agaagagatg atctggccat
    23161 taagtatgcc acctgcctta ccggaaaaag acgaagagat cattattgca aaattaaaaa
    23221 atttcgaaga tgtcttgtat cgacgttatt tagcaaaaga atacgggaag cgaaaacaga
    23281 tggtaagcgg tattcatttc aattttgaat ttggcgatga gttgctaaga acattgttca
    23341 gccatcagga agaatttcaa gatttttccg aattcaaaac agaactttat ttgaaaacag
    23401 cgagaaactt tatgcgctat cgctggatga tcacttattt attcggtgct tcaccaatga
    23461 gtgagaagaa ctacttttta gatgaatcac atccgcaaga acctgttcgc agtattcgca
    23521 acagtgcgct gggctatacg aatcatccaa atgtgaaagt ttcctatgct tctatgaaac
    23581 agtatttagc agatatcgag cgaatgatcg aagaagggaa actttcggag gagaaagaat
    23641 tttatacacc gcttcgtttc cgaggcggaa agaaagtcgc agatttagca acaacaggtg
    23701 ttcgttatat tgaattgcgg aatatcgatt tgaatcctta tgcaagattg ggtatcaatc
    23761 cagagcaagt tcggttctta caattattcc tgatgtacat gttatggaca gaagaaaaag
    23821 aagactgtga ccaatgggta gcagaaggta cgactcgaaa taacaaagta gcactagaac
    23881 aaccatcaga tcaaacagaa tttcatcaag aaggtagaga aattcttgaa ggaatgaagc
    23941 aaatgctggt tgaattggat tggttggatt ctctttattt agtagaggaa gcattgactc
    24001 aaatggatca tcctgaacaa acgttagcag cgaaactcta tcaagaagca cagctatcga
    24061 gtcagcaaga agttgctgtg gcattgggac atcaatatta taaagaaagc catgaacgtc
    24121 cctatcagtt ggccggtttt cgcgaaatgg aactttctac tcagatattt atgttcgatg
    24181 ccatccaaaa aggtgtccaa gtcaaagtat tagatgagtc ggatcaattt ttgcgtctgc
    24241 aattccaaga ccatgtagaa tatgtgaaaa atgcaaacat gacaagtaag gacagctata
    24301 tcgtcccact tatcatggaa aacaaaacag taacgaaaaa agtcttaaaa gaagctgggt
    24361 tccgggtacc aggaggcgca gaattttcat ccatggaaga agcggtaaaa gcttatccga
    24421 gatttgccga gcaggcattt gtgatcaaac ctaaatcaac caattacggg ttaggtatca
    24481 cgattttcaa ggaaggagct agtctggaag attatcaagc aggtttagcc attgcttttc
    24541 gtgaagacag ttcggtttta gtagaagaat ttatgccggg aacggaatat cgtttctttg
    24601 tgatcgacgg agaagtccaa gccatcatgt tgcgagtccc tgctaatgtt attggtgaca
    24661 gtatccgaac agtgaaagaa cttgttgaag aaaaaaatag tgaccctttg cgtggaacga
    24721 atcatcgtgc acctttagaa ttgatccaat taggtgaatt agaacaattg atgttgaaag
    24781 aacaagggtt gacgatcgaa tcagttcccc aagccaatca aattgtttat ctaagggaga
    24841 actcaaatat cagtacaggt ggtgattcga tcgatatgac tgatgaattt tctgaagctt
    24901 acaaaaaaat cgccgtttct gcggtagaag cactaggagc taagattagt ggtatcgatt
    24961 tgattatacc agataaagaa atcgatccta caactgataa aaaagcatat gggatcatcg
    25021 aagcaaattt caatccagcc atgcatatgc atgtttatcc ttttgcagga aaaggcagaa
    25081 gattgacgat gaatgtattg aaattgttat atcctgaagt attttaaaag aaaaagcttt
    25141 tgacagattg tcctatttga tgtcaatctg atcaaaagct ttttttgcat gtaaaaattt
    25201 atgtgttttt tcgttttaaa ataaacgatc ccagaagctt tttttctttt ttggtttttc
    25261 tttttcagct ggcgaagagt tttcttctgg gtattttttt tcgatatcaa tcacaggttc
    25321 atttactgct tcttttgctg ttaagagcaa tccgaattcc tcaggatttg cagtgacgta
    25381 atcgttgact acagtgaaac ggctattgtt tttcgttgct agctggatat attggttttg
    25441 gacagaaagg ggtagagccc cattcaagag tatggaagca tctggatgtt ttttgagttc
    25501 ttttaaaaag ttttctttgt tttttggttg gatcatttca gcaacagtca tactaagata
    25561 gcagcgttcc ctgaatgtcc ctaaatattt atgctgttct tcagggttca ctaaaggtgt
    25621 accataaagt cccttatcca aatggctttt tacatcatct tgtgccataa aaaataccct
    25681 ccttcttctc tttgtctttc ttacgattat agcatattcc caataatacc taaaacatat
    25741 gaaaaagcgg ttgcttttgt tcaacgattc acttaaaata agaatgaaaa tcattctcaa
    25801 ttagaaaggt ggattggatg cgctacggac gactagtagc attattagtt attttaagta
    25861 gtatttcatt gttcatcgga gtatcgaatg tacaattgtc agaactgctc cagttagatg
    25921 ggcaaagctt acaaatcttg ctagtgactc gtttgccacg aacgatttgt ttgatccttg
    25981 tgggagcgac cagtagtatt tgtgggttga tcatgcaaca tttgacccaa aataaatttg
    26041 tttcaccaac gactgcgggc acgatggata gtgcgcgttt aggtatttta gtggctatga
    26101 ttttcctacc tggtgcatcc ttgattgtcc gatccttgac agcattttgc tttgcttttg
    26161 caggaacatt gcttttttta tcccttacgc gattgttcct ccagaaaaat caattgatgc
    26221 ttccgttgat tggagtcatg ttagggaata tcattggttc agttgctact ttttttgctt
    26281 atcaattcca gttggtacaa aatatgactt catggcttca agggaatttt gcgactgtga
    26341 tacgaggaaa ttatgagtta ttgtatgctg ttgttccatt gttgctcttg gtttggctat
    26401 ttgcttaccg atttacgatc attggtctgg gcgaatcgtt tgcagtaaat ctgggaatag
    26461 attaccagaa gatgcagttt ttaggcattg gcttagtatc attggctagt gcagtcatgt
    26521 tgatcatggt aggaagcatt ccttttatcg gagtgatcat tccgaatctt gtctctagaa
    26581 tatatggaga tcaagtgcac aaaacaattg gcgtaactgc tttagcaggt agtttgttct
    26641 tagtattttg cgatcttgtc gctcgcgtgt tgatttttcc ttatgaaata ccagtcagtg
    26701 tgatcgttgg aatcatcggt ggggctatct tcctttatct tctgataagg ggacgacgat
    26761 atgcttaaaa aaaagccatc tatttttatt ggtatgcttg ttcttgtttt atttgttaca
    26821 ggaatgtact tgacgatcca tacatatgga aactggcatt ttgcatgtgc attgaggagt
    26881 aagaaaattt ttgcatttat ccttgtctcg ctagctgtca gcagtgccac aatcagcttt
    26941 cagacaatta cgcataacca gtttttgact ccttcagtat tgggacttga gtcgttatat
    27001 gtccttgtcc aaacggtcct tttcttcttt atcggaggag tgacgatgct tcagcagaca
    27061 ggtacagttt ttttcttatt gaacgttggg ctgatggtcg ggctgagtct attgttattt
    27121 ttctttcttt tgaaaaaaat gagagcgaat ctttttttat tactgatgtc agggatgatt
    27181 ttaggtacgc tttttggtag tgtcagtacc tttttacaag tcatcatgga tccgaatgaa
    27241 tatgatttgc ttcaaggcag attatttgca agctttggca atatccagag tcagtatctt
    27301 ttgcctgctt ctttgatcat tatcggctgc tggtacctgt tatttcgata tcgacatgtg
    27361 ctagacgttt tccatctcgg aaatgaacaa gcagtaaacc tcgggataga cacagatcgt
    27421 tttgaatttt tgattttatg ttgtgtcagt cttttgacag ggacatcaac ggctcttgtg
    27481 ggtccagtta cttttttagg gtttattgtc gcaaatatca gttatcgtgt cttttctact
    27541 tatcgtcatg gtcagctatt tatcggaagc tttctggtag ctatgctgtt tctgacagga
    27601 ggacagctcg cagtagagca gattttcggc tggaatacaa cagtgagtgt cgtcgttgaa
    27661 tttgtcggag gaatttattt tgtcacaaaa ttgattcgcg aaaggaagag tatcctatga
    27721 ttgatttaca aaaggtcaat aaactgtacc atggaaaatc agtggttaaa gatgtacagt
    27781 taacgattcc tgaaaagaag ttgactgctt ttatcggtcc aaatggtgct ggaaagtcaa
    27841 cggtgttgtc gatgatcagt cgtttgatac caaaagatac aggtgaaatc tatttagacc
    27901 ataacgaagt aaaggcttgg aaatccaatg aattagccaa aaaattatcg atcctacgac
    27961 aatcgaatga aataaatgtc caaatcaccg tgaaagaatt agtagaattt ggacgatttc
    28021 cttatacgaa aggaaaattg acgacaaaag acgaggaaat cgttcaggaa tcactggaac
    28081 acattgggtt agaagaaata gcggatcaat cgattgacac tctttcaggc ggtcaactcc
    28141 aacgtgcgta tattgcaatg gtgctagcgc aagacacgga ttatatttta ctggatgaac
    28201 ctttgaacaa tctagatatg aattttgcgg ttcaaatcat gcagatttta aaaaatttag
    28261 tacaagaaat cgggaaaaca attgttattg ttcttcatga tatcaacttt gctgcaagtt
    28321 atgcagacga aattgttgca atgaaagatg gacagttatt tacgcaagga acgacccaag
    28381 aaatgataaa aaaagatgta ttggatgaat tatacgaaat ggacatacgg atttgtgaga
    28441 ttgaaggccg cagattctgt ctttatttct aaaactaaca ttaggagaga agagatgaaa
    28501 aaattagtag taggtatctt gattctagca tcatttggtt tagcagcatg tggaaatagc
    28561 aacaacacca gtcaggcaga cacaaaaaaa agcagcacac aaactgaaac tacattgacg
    28621 ataacagata gtaatggaga ccaaatcgag gtgccaaata atccagaaaa agtcgtcgta
    28681 ttcgacaatg gttctttaga tacgatggat gctcttggtg ttggagataa ggtagttgga
    28741 gcagctacaa gcagccttcc tgagtatctt tcatcctata aaaaagtaga atcagcaggt
    28801 ggaataaaag aaccagactt agaaaaaatt aatcagcttc agccagatct aatcatcatt
    28861 tctggccgac aaagagattt tcaaaaagat ctaagtcaaa ttgctccgac cattttcctt
    28921 tctttagatg cgaaaaatcc atgggaatct ttccagcaaa atgtcactgc tttaggggag
    28981 atctttggta agcaagaaga agctaaaact caattagagg aattatctag tgcaatcgat
    29041 cagacgaaaa agaaagcaga agctactgac aaaaaagcac tagtcacact tgtgaatgaa
    29101 gggcaattat cagcctacgg atctggttct agattcggtt tcatccatga tttatttggc
    29161 tttgaacaag cagatgatca aatcgaagca tccactcacg gtcaaagtgt ttcttatgaa
    29221 tatgtgctgg aaaaaaatcc ggatatctta tttgtagtag acagaacaaa agctattggt
    29281 ggagacgaca gcaaagatga tatttctgcc aatgaactgg tagcacaaac gaatgctggt
    29341 aaaaatcagc agatcatctc ccttgaacca gatgtctggt atttaagcgg gggcggttta
    29401 gaatcaatga aactgatgat cgaagatgtg aatcaagcat ttaaatagca taaataacag
    29461 aggattaaac tctcatacta tgtaacaata atgtttctta cattcttaaa tagcaagagc
    29521 ctatcctcaa agaagttatc aaaaaccatc cgtaaaatcg tattgatgat tttacggatg
    29581 gtttttattt atttgagaaa tcttttttca acgtgaattc attatctaca tcatacgggt
    29641 tgattctaga atggggagtg gcaaaaaata gtgtgatcca ttttttcagc atcaagatcg
    29701 cctcctttga tttgaatcaa aggtacaaag cgaaacttag ataaaactta aatttagata
    29761 tttttatttt gtaccgatct cttctttaaa cgatgttcca tctgctgctt ctcggcaata
    29821 agtccactag actagaaaat atgagaagct attttctgtc cagcgttctt attactcaaa
    29881 acaaatcgca gttgtcacaa tctcttctaa acgatgttcc atctgctgct tctcggcaat
    29941 aagcccacta gactagaaaa tatgagaagc tattttctgt ccagcgttct tattactcaa
    30001 agcaaatcgc agttgtcaca atctcttcta aacaatgttc aatcagctga ccttcggtat
    30061 tagctcaaag cactgatttc acaacctcta tttaggcatg tgtctcagca agcggttgat
    30121 agttgatgat ctgcattttt cgataaaaat cggcgggaag cttactccac cgttttagta
    30181 attgatagaa ataactctct tctgctttga ttttatactc gcttaatatc aatccaaaac
    30241 tattcgtttt ttttgaagct aattttttat aaatatccaa tgctttggtt ttatcttcat
    30301 tgacaaagag tgtttttact tcaatataag aaccctcgat attttgtgtt tcttcgataa
    30361 aatagatgtt ttttatatat tccttcatag tgattcctcc aaagaagtct tttatttgat
    30421 aagtttactc taccgaagag ttgttaataa tccgtgaaca aaaagtaatt ctttttccaa
    30481 tagttgttaa aggtttttta ttttttatag tattttttgt tatttaagaa aggaataagg
    30541 ttaaacaaat aacaggttgc tttttgggtc tttttccgtt caagaaactg aacgaagaaa
    30601 agggaaagtt gtctcttttg tgataagaga aatcataata aacgaatgac ttactttcca
    30661 ataaattgag aacagtcaga accagacaaa ttagttgcat ctgatgaata aagtgattat
    30721 tctatgacat gaggtgatac agatgaaatt agaagtgaca aaagaagcac aagaagtatt
    30781 gaagaataaa ttagaagcag acgatcaact tttattagat atcgaaaacg gtgacggtcc
    30841 atttgcagaa agccaagtca gttgccaatt ggatacggca tttcgattga tcattgtcaa
    30901 aaaagataca caaacagatc taagtcttta ttctgtagtg gctgatacac cagttggacc
    30961 aatcaaaatc aaagacagtg caatacttta catggatgat ccatccacac ttgctttaga
    31021 accaacttat aatagtttac aattaaaagg accaagcggc ttgagaaaag gcaacttgca
    31081 agttgttcga aaagactaga gggataaaat gggaaaattg gcgatcatca gcgacctaca
    31141 tgtggacatc aataaattcg gcgaatcaga gctgatgcag ctttggcaag ttttgcaaaa
    31201 gcacaagatc actcggcttc atctagccgg agatacggct aataaagtag accgttgcct
    31261 agctgttgtc gaatttttcg tcaataaagg attatctacg acatttcatt tcggcaatca
    31321 cgagttggca gatgtgccca atgaacagat gatggaccat tttccagacc cacatttttt
    31381 aaatgaacgg tatattgctt taaatgagca gaccgttctt ttagggatga atggctggta
    31441 cgactatcag ttttccgaat tgaaagatta cgaggcaatc gtacgaatga agcgtttgta
    31501 ttggtatgat cggttcatcc agcgtgggaa aacagatctc gaggtcaatg cagaaatgct
    31561 tgcagctgca aaaaatttgc tagaccagct ggaagcaaaa aaacttgagg tgattttatc
    31621 cactcatttc gttcctaaac gggcatttat catgtatcaa tctgctcctt atgagcgttg
    31681 gaacaaatta aatgcatttt taggatcaga atcattcgga gaattacttg accgttattc
    31741 aaatatcaaa caagtagttt ttggccatac gcatcgtcgc tttgaagata aatccatcgg
    31801 tcacacgatt tacagctgca gaccttttgg ttattattat gaatggcagc tgacccgaga
    31861 ttttgtcttg aaagaacagt tgctagacag ctatgatcct atgaaattac gtgtcctctt
    31921 gcgtgcccat cacccagctt ttcaggccta tcaaacacaa catttgcaag aggaatttga
    31981 acaagcgatg acaatcgttc cgtattgaga cagcattagt aatgtgtaaa agaaaatacc
    32041 ttgtaaaaca taaggataag taagagcagt agatccattt atcgtggata tgctgctttt
    32101 tttgcggaaa ataatcagcg aatgtttatt tgatcggatg atttgtaact cgcagagtac
    32161 tagatgcaag cgtgtattct ttttttgaac gataatcaca aaaaaaaata taatatacat
    32221 tttttattta attataatta atattgattg aagtctaggc agtcaagtcg agagtgtaaa
    32281 atattttgtg taaatgaaaa aatccataca aaaaaggaag tc
//
LOCUS       DADLIO010000027        30460 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.027, whole genome shotgun sequence.
ACCESSION   DADLIO010000027 DADLIO010000000
VERSION     DADLIO010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.027"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(451..1761)
                     /locus_tag="JOX41_001393"
     CDS             complement(451..1761)
                     /locus_tag="JOX41_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HAY6449145.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1773..3131)
                     /locus_tag="JOX41_001394"
     CDS             complement(1773..3131)
                     /locus_tag="JOX41_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAY6449146.1"
                     /translation="MSDKIGYMFGDLGNCFILGLVNSFLMIYYTNVLGVSGAIVGTLF
                     LISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKYPFCLVTVILFLPFVQHLPMT
                     VKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDRTSLSTFRSIGSAIGGSTTGF
                     FIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYMLTCKLTTERVRVVKNEKVSA
                     SQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLFNDYFHNKQAMSVALLFTYGT
                     VVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFLHITNAWVYLILLFIATLGSG
                     LFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARKVGQACAGAVGGFMLALIGYQ
                     SSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLVGYPLNRSKTVFIGEELKKIN
                     ER"
     gene            complement(3333..4901)
                     /locus_tag="JOX41_001395"
     CDS             complement(3333..4901)
                     /locus_tag="JOX41_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HAY6449147.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4905..5315)
                     /locus_tag="JOX41_001396"
     CDS             complement(4905..5315)
                     /locus_tag="JOX41_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HAY6449148.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5312..6235)
                     /locus_tag="JOX41_001397"
     CDS             complement(5312..6235)
                     /locus_tag="JOX41_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HAY6449149.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6232..7110)
                     /locus_tag="JOX41_001398"
     CDS             complement(6232..7110)
                     /locus_tag="JOX41_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HAY6449150.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7097..8434)
                     /locus_tag="JOX41_001399"
     CDS             complement(7097..8434)
                     /locus_tag="JOX41_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HAY6449151.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8437..9540)
                     /locus_tag="JOX41_001400"
     CDS             complement(8437..9540)
                     /locus_tag="JOX41_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HAY6449152.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9614..11122)
                     /locus_tag="JOX41_001401"
     CDS             complement(9614..11122)
                     /locus_tag="JOX41_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAY6449153.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11088..11780)
                     /locus_tag="JOX41_001402"
     CDS             complement(11088..11780)
                     /locus_tag="JOX41_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAY6449154.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11802..12776)
                     /locus_tag="JOX41_001403"
     CDS             complement(11802..12776)
                     /locus_tag="JOX41_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAY6449155.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13076..13948
                     /locus_tag="JOX41_001404"
     CDS             13076..13948
                     /locus_tag="JOX41_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAY6449156.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14406..16604)
                     /locus_tag="JOX41_001405"
     CDS             complement(14406..16604)
                     /locus_tag="JOX41_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAY6449157.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEIEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16836..17828
                     /locus_tag="JOX41_001406"
     CDS             16836..17828
                     /locus_tag="JOX41_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAY6449158.1"
                     /translation="MVTIKDVAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17888..19309
                     /locus_tag="JOX41_001407"
     CDS             17888..19309
                     /locus_tag="JOX41_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HAY6449159.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSLPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19302..20801
                     /locus_tag="JOX41_001408"
     CDS             19302..20801
                     /locus_tag="JOX41_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009224330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HAY6449160.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20840..22234
                     /gene="uxaC"
                     /locus_tag="JOX41_001409"
     CDS             20840..22234
                     /gene="uxaC"
                     /locus_tag="JOX41_001409"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HAY6449161.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22393..23076
                     /locus_tag="JOX41_001410"
     CDS             22393..23076
                     /locus_tag="JOX41_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HAY6449162.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            23078..23914
                     /locus_tag="JOX41_001411"
     CDS             23078..23914
                     /locus_tag="JOX41_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAY6449163.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            23925..25679
                     /locus_tag="JOX41_001412"
     CDS             23925..25679
                     /locus_tag="JOX41_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6449164.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(25955..26296)
                     /locus_tag="JOX41_001413"
     CDS             complement(25955..26296)
                     /locus_tag="JOX41_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HAY6449165.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26364..28535)
                     /locus_tag="JOX41_001414"
     CDS             complement(26364..28535)
                     /locus_tag="JOX41_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HAY6449166.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28746..29603
                     /locus_tag="JOX41_001415"
     CDS             28746..29603
                     /locus_tag="JOX41_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAY6449167.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            complement(29674..>30460)
                     /locus_tag="JOX41_001416"
     CDS             complement(29674..>30460)
                     /locus_tag="JOX41_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAY6449168.1"
                     /translation="KLSIPTTTPEETLDQVFEFFDRYELKGIGIGSFGPIGIDKTKDN
                     YGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTDVNAAAYGELKQGAAQGKNSCIYLT
                     VGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPDDHYEGTCPYHKDCLEGLAAGPSIE
                     ARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLTLAPEKIILGGGVMNQDHLLQKIRQ
                     QFVELMGGYMETPQVSEYIVRWGLPNESGIIGSLLLAEHEHQK"
BASE COUNT         9099 a         6274 c         5391 g         9696 t
ORIGIN      
        1 ttgtcttgaa ttgaatcaag acgccctaca catttggttt gtcttacttt gttcagtttt
       61 caaaggtcta cttcatcgag agtgtttccc gattcatttt tggctgccgt agcaactttt
      121 atatcatatc agagagacaa acgattgtca actctttttt aaaagttttt ttcgatttcg
      181 tttttcgaaa tctttcagca actcatttat cataacttat cgtttgttat ttgtcaagaa
      241 cttttttgaa gtttttttcg atagaatcaa gcttcgcaag tggttctttt taacgactta
      301 gttatcttat cacgtctaaa aacatgtgtc aactcttttt tggaattttc ataaaatgtt
      361 tcaatgaagc gcgacaacgt tgtttaatat atcattaaaa aaaataaagg tcaagctaaa
      421 atattattta agcttgacct tattataatt tcaacgattg tcaaaagtat tgtttgcagc
      481 tgtgttgcca gtttctatag ataaatcaca gcttttgaaa cataagtttt gtactgcttc
      541 gattcgcccg aattcttttg cagttatttg gcaatgagaa aagcagacat cttctatagg
      601 cttttcagga aatgctacta aatcaaaagc tcgggaagga agtgagtaac ctggagaaag
      661 gcatgcctgt acgtttttga tgtgtatgtc tttgactttc gtcatttgct ttgattcagg
      721 tatttcttca gccactgctt gccaactttc tggcatttga gcaaggtcat tgctattttt
      781 tctattgtat tcattatgcc agtccattat ccaagaaaaa ggaaattgta catcaatcat
      841 attcagattt tctaccctga tattttcgat cactccccct ctttcttttg aagatttcat
      901 tcgaatacca cagtctgact gaaaaaaatc gatatcgtga atatatacgt cactaactcc
      961 agcactaact tcgctaccaa tagttacacc gtatcctgaa cggattttac atctagcaac
     1021 ctcgattctt gatgattttc gattgactct tgcaccattg ccatctctgc cagacttaat
     1081 agcaatacaa tcatcaccac aggccaaatc acattcatag acacgcacat ttgttgaaga
     1141 atcaatatca atcccatctg tacttggtcc atcattgttg cggatgatta ctttttctac
     1201 taatacatcg ttagaataag tgatttgcaa gttccaaaaa cctgatttct gaaaaatcaa
     1261 atcacgaaca acaacatgtt ctgcatgata cagtaaacaa gcgcgtggac gtttaatagc
     1321 ataatccgca atccaacgaa gtcccttttg atcgtattca gctcttgtcc cgcttttttg
     1381 atcttttccc caatacagct cccaccaatg gtctccttga ccgtcgatta ttccttttcc
     1441 ttctataaga atatctttcg ccgagagaac attcaaaatc gctgctggcc atttcatttc
     1501 tacgccggct actcgtgtat cgatttctgg aaatgcttcg atatctgttc tccccttgag
     1561 gactgcacct tcttcaaaga taagatgact cttatctttt aaaaaaaggg ctccgactaa
     1621 ataaatgcct tttggaataa atacaggtaa gtgttctttc gcaccttgat cgattgcttt
     1681 ttgcagtatt attgtatcat cttgttgagt gtcgtttgtt ttaaagttca aagcattgat
     1741 aatccctttt tttgtccgca atacgtttct ccctatcttt cattgatttt tttcaattct
     1801 tcaccaataa atacagtttt tgaacgattc agtgggtaac ctactagcaa aatgattgcg
     1861 gatacaaata agcagaatgc tggtaacaag tttgccatcg tataaatcct ttcttgtact
     1921 aaaactgatt ggatggctcc acctgttgta gacgattggt aaccaatgag tgccagcata
     1981 aatccgccta ccgctcctgc acatgcttgt cctacttttc tcgcaaaaga atttactcca
     2041 tatactgttc catcttctct taagcctgtc ttatattgat gataatcaat cacgtcagta
     2101 atgaatgccc agaccatcaa attgaataaa ccagatccta aagtagcgat aaataaaaga
     2161 atcagatata cccatgcatt tgttatatga aggaaataca tcagcaagta catacatgaa
     2221 gaagcaagta acgcaaatac gcttgcttcc tttttaccaa ataattttgt cagctttgta
     2281 gcaaatggtg ctaaaactac tactgttccg taagtaaata aaagagcaac agacattgct
     2341 tgtttattat ggaagtaatc attgaataaa taagtcatat tcgtcccagc taaaatctga
     2401 ttgatcacaa tgaaaatgtc aacaatgact aaaataatca gtgctcgatt agctaacaaa
     2461 ccttttacca actgagaagc agatactttt tcgtttttga caactcttac tctttcagta
     2521 gtcaatttac aagttaacat atatgcgaca aatgctattg cagcacatcc gattgaaatc
     2581 caaaagaaat gattccctga aacgacttgt tgtccactct tgttatgggt atacattaaa
     2641 atcggaatga agaatcctgt agttgatccg ccaatcgcag aaccaatgct tcggaacgtg
     2701 gacaacgagg tgcggtcatt aggatttgag ctaattgctg ctgccattgc tccatacggg
     2761 atattgattg ttgagagaaa aatcccataa acaatgtatg aaacaaaaat ataagcaatc
     2821 ttcaccgtca ttggaagatg ttggacgaat ggcaaaaaca aaatgacagt cactaagcaa
     2881 aatggatact tcatttttct gatccaagga ataaatcggc cagtttctgt taactctgag
     2941 acatcacata atcttccaac catcacatca gcaaacgcat ccaaaattct cgaaatcaag
     3001 aataacgtac ctacgattgc ccctgaaacg ccaagaacat tcgtataata aatcatcaag
     3061 aaactattga ctaaacctaa aataaaacag ttacctagat caccgaacat gtagcctatc
     3121 ttatcggaaa tcccaaattc ctttttttct tgtttttata ttcacaatgt tggcttttta
     3181 ttgcattatc ttgacagata aaaaacaaaa aataatctaa aaacattgat gcataagatt
     3241 gataactttt tttacataac aatatataca aacaaaaaaa ttcactaact agtgaaaata
     3301 agttagtgaa cctcatttat taaagaatta aattacagat gatcttttcc atcatacttg
     3361 aaaaactcaa aatcagcata acttcctctt tttttattta gatcatgcac tgctatcccg
     3421 ataaaatttc cagtaaaccc tcctgagagt atacacatgt ttttttgcgg acctactttc
     3481 ttccattctt cagttgatac gtctttcaaa tgaaactgtg ctgtctcttt ctttacagtg
     3541 actttcaaaa aagtcttctt ttctgtgagt ggaatcgtcc aatcttctat ttgtgctact
     3601 ccgttttctg attctatcat acgtaggcat tttcccttgt cctcattcca agtaacataa
     3661 caataaatat aattggattc atttaagtac agtaccagtc cagccatctg attaaaatta
     3721 ttaggcatgt attcaaatgc tgtctccgca tcaaaagtaa aatccgtttg ccgaatagct
     3781 aacaaatgat gttcgaaggt agattgaaga gattcaccgg aaatcagacg taaaaaacct
     3841 ggtctacatt ttgtatcaca ccaatcagca tttggcaaaa tgcgtctggc attccagttc
     3901 ttctttagct ctccttcaaa tgtatccata aactgatgat ctttttcttg ttgtacctct
     3961 tcatttgtct caatcattat ttcttccatc ggagttgtct ggctatcttt aagtcttaac
     4021 caatcgtcgg acgtccaata cacttcttga atagcggttt ctcttcccaa aatagccgca
     4081 ccgtttaatg gtctggtaca aagatatgtc atgtaccatc ttcctgacgg ggtttgtact
     4141 aagctcccat gtcctgtaca ttgcaatgta gaagcaggtt tgtcactagc tgtcagcata
     4201 ggaaaaccag gatcaagctc gtaaggacca gtaatattct ttgctcggca aactgtaact
     4261 gaatgtcctc ttcctgtacc gccttctgcc gtcatcaaat aataataccc gttacgaaaa
     4321 tacaaatgtg gtgcctccgt tttcgctaat tctgtacctg caaatatttt atagatggga
     4381 ccatcaagct tcttcttctc tgcatcatat tcttgtaata cgataccgct ggatttattc
     4441 ggtgtgtcca gacgataatc ccatagttca ttgacaagcc atttttttcc cgtttcaaga
     4501 tcatggaaca aagaaggatc aaagccgtta ctatttaaat aaattggttc ggaccaagga
     4561 cctgtgatct cagatgcagt gatcaaataa ttgtggacat ctttaaacgg acggcctgca
     4621 cttttgacat ctgtgtaaac aagataaaac aatccatcag cataactgat ctgtggcgcc
     4681 catatacttc catttgtagg atttccttgc aaagatactt gagtggtcaa aatatccgtt
     4741 gtatgtgacc agttgactaa atttttcgac tcatatactc ggattcctgg aagccattca
     4801 aaagaggaga caataatgta ataccgctct ttcactctta atatattagg atctggattg
     4861 aatcctctta aaataggatt tttcactttg atagtctgca tgattcaggc tccttttctc
     4921 attcttactc gatataaact gaatgcccca gctgcgaaat aaaaaaatgc aaaaggaaac
     4981 gcaataaact gagtgccaat caacaatatg aatcctgtta taaaatacaa accagtggca
     5041 gttgttaagt attttccttt agcagtcaaa aacaatgcta ctgctaaaaa agcaagtgaa
     5101 ataaacaaca caacggcaaa cagaccagtc atgtcctgta ataatccaaa tgtattttct
     5161 aaagacaaag ttgaatgatc tacagcaagc gactgataac tttttttaaa ctctgacgca
     5221 gacatattac ttaaagtaac tgctaacccg ccaaagaaaa tcaaagatag actgccaccg
     5281 accattccta gcaatagttc ccattttctt ttcatttctg aaccccctgc ttttctaaat
     5341 gtatccattc aggtcttttg atcgatgttt cataattgtt attacgttca gagaatttga
     5401 cagtctgttc atttttcttg tcatcccaat tatcccaacc agttgggtga acatgcccac
     5461 ctatcttaca cgcttcaaat aagacatttg catacggacg ccacggtctt cctaaataga
     5521 cgtttctagt atcaggttct gcagtcaagg tacagctttc aaaacgatac cctgtttttt
     5581 gatttttcgg cgtagatgct gctgtgatgt atccaggatt tttactggct aagctatgga
     5641 tatgacactg atgaaaaacg gcatctgccc caccaaatat gaaatccacc gttccttcaa
     5701 tccagcaata ttcataggtc tgacgacaat actcaggatt ggcagaagcc ggtgtacaaa
     5761 aaggagtacc atctttttgc aaatcaggca acggacccgt gcataaggta tcctgataac
     5821 cagatagtcg acagtttttt aaagatacgc gatctcctga attgaataaa gcaacagcct
     5881 gtcctacctt ttctcctgga cctgctgtat tttcgatgtg aagattttct aatacgacat
     5941 tcgatccttc taagaaaaaa gtagcacttc ggaaagtccc taactggcta ccgtcaagat
     6001 actcctgttt tgcaaaacga ttaccggaga taactactgt tcctgctccc acaagtttaa
     6061 aattggataa tctgctttct atatattcat catatcttcc ttcttttact atcaagacct
     6121 ttggatggct atccggcagg cctgccaaat aatcgattcc ttcttggata gtttcaaaat
     6181 ccgtcggggt atctatagca ttctttccaa ttatcagttt gtctttcatc ctcataaatg
     6241 ctcccttatg aattgtttcc aaatatttct catttcttgt gtttccatat gaccgcctgt
     6301 taaagaaaaa gaagaaaagt tttctggact acccattgat tgatactttt tgtccagccc
     6361 ttttctcagc ttcagtacgc cttcgtccaa gcacatcgta tcgttttttc caactaagct
     6421 aagacgaggg cgcggagcga ttttttcttg gattgctaac gttgtataag ctgtcaatag
     6481 atttggcaca tagtaataaa acccatgatg atctaggcgg cgatgtagca aaagtatttc
     6541 gatgtccacc tgtgccgcta gatcaataca aactttgaca cgagaatcca atgctgtcac
     6601 ccaccagctt aataagcctc ccatagaaag accaatcgtt gcgagccgtt gagtatctgt
     6661 gtcttccctt gtctccaaat aatcgatcaa gctgatcaca tcataaatac gcattcccca
     6721 taacgttttt cctgttaata aaaattgttt gaacaactcg ctttcagaaa tacctccgcg
     6781 ttcttcaaat ccccaagcat caatcgacca aacagcatat cccattcctg tcagtacttc
     6841 tgcaaaagat ggagaagcta agtaaggagc accatggatc aattcacttt tcccgactga
     6901 aaaatctccg ccgtgagaat gcaggtaaag gaccggcgga aacggtcctt ctttttctgg
     6961 ataagcatag agggctggta ctgtttccaa ttcatttaag tacaattgat agtattcaag
     7021 cataaaaccg ttttgttttt ctcggtataa tcgttttcca ctaggggtat gtctgctaga
     7081 tggagcacct aaaaaatcat tcaactgcat aagcaaagtt tttacgaaca accagttcat
     7141 ccatattttc tgattgattt gattggaatt tctcaatact gatttcttta gtattttcta
     7201 atagaaatgc tggtccctcg tgattttcaa tcgacatctg gttaaaggaa accttacccg
     7261 caaagccaat ataaaatcct tgtctgctca tttcctctat tcctgtcatc atagcaggaa
     7321 caccgggaac tgcatcttgg gccatcgaga catcgatatt gtcaaatgtg atttcttgta
     7381 tgaattgttc cgctaatcca taaataaaac ctgcagaagc atggacattc cttgccgtga
     7441 tattcgaaaa atggatcctt ctgaatgctg gtgtccgttc atctatcgga taagcctttt
     7501 tttcccatac atacggttct ttccctcgcg gaccacagaa ataataaaga ttcagtataa
     7561 atggacacat cacattatcc atgactatat tggatactcg aatatcttca acgatcccgc
     7621 ctcgacctcg tctagatttc aatcgtattc ctcgatcagt ttcttggaag atacaatttg
     7681 aaatggtaat attacgaata ctaccactca tttcacttcc taatacgaca ccgccatgtc
     7741 catggaccat cgtgcaattt gtgatcgtga tattttcgca agcgatcctt tcgtacgtat
     7801 cttcagtccc tgccttgatt gcaatacagt catctcccac gtcaatatgg caattactaa
     7861 tacgcacatt tttgcatgat tctggatcaa ttccgtctgt atttggtgaa tccgctgggt
     7921 tcaagatcgt caagttatca aacgttgcat tactgcaaag aatcgggttg atcgtccaac
     7981 ttggtgactg gatcaattta atatctttca cagtaattcg atgacagtta tggaaactca
     8041 tcaatttagg acgaggataa gcgagattat ctggttcatt tctaaaagta tgccaccatt
     8101 tttttccatt tccatctaat gtaccgaaac cagtgacaga gatgttctct acattttgag
     8161 catagataca ggaagcataa acttttcgat ggactccttc ccaacgtgaa tgaacaacag
     8221 gataatcttt tggatcgtca gagaatttca gaaccgctcc tgcgcttaaa tgaagttcga
     8281 cattgctttt taaaaataaa gctcctgtta gaaattcacc tgctggaaca actacggtcc
     8341 cgcctccgtc acttgctgca gcatcaatgg cttgttgtat tgcttcagta ttcaattcat
     8401 caattgatgc gccaaatgtc aaaatatcat acatatttat aatgcctcca cttcaatcaa
     8461 tgcttgcaag aatgcaccaa cgcctttttg atcattacaa ataattggtt cactgatgta
     8521 gtaagcatat gaaccatctc gctgatctgc tccgcctaac cctgctactt gacagttttt
     8581 attcaagttc agccagcctt cttttgtttc cagaacaaat tcatcaagta atccttgatg
     8641 tgatttcttc acttgtggaa gccattcttc tttgttcagc agtcccaaac gtattccttt
     8701 agccattgcg taaacaaaca tactactgcc ggaagcttcc agataatttc ctttccgttt
     8761 tgtttctgtt gttacttgat accatgtccc gctgttttct tcttgatatg gaagtaatgc
     8821 agccagtgtc ttttctagaa tttctttcag caaagaacaa tctgtttctt catgaagtaa
     8881 ttcataggta tctgctgcag ccatcaaata ccagccaatc gatcggctcc aaaaatgatg
     8941 ggatagacct gtttttggat cagcccatgg ttggaccttc ttttcatccc atgcatgaat
     9001 cagcaaattt gtttttggat cgaatagatg tttataactg atttcaaact gtctcaaaac
     9061 atcttggtaa tctttttctt cactaaaatt ctggataaat tcagcataaa aaggagaacc
     9121 catatataag ccatccaacc aaatttgata aggataaatt tctttatgcc aaaaagctcc
     9181 ttcggatgtg cgtggatggt ttgccaactg ctgggaaagg agttctgctg cttttttata
     9241 tttttcttcg cctgtttctt tgtacaataa aaagaaaagc tttcctgtat ttacatggtc
     9301 gatattgtat tcttcaacgc tgtagccacg gatcgttcca tcttcttgca cgaaatagtc
     9361 gatattgtct tttatgaaat caaaataaat tttttcttgg gttcgttccc aaagtaattg
     9421 gaacccttta agtacgacgc catagtcata agaccatttt cctttatacc acttttcttc
     9481 atataagcga ggtgttcttt ccatgatact ttttgctaat ttctttgacc agttttccat
     9541 tatttgctct cctttaaaaa ttaaaatagg atttgggaca aataccaaga agtatttgtc
     9601 ccaatcgtct atattactgt gccgctgctt tgtatgcttc ctcgtactct tgtgtgattc
     9661 gatcgcctcc ttgtgctttc cagtcttcta cagctttttt gaatccatct tcgtcaagct
     9721 gtcccatgat gtattgcacc gtagcatcaa tgacgatttt ttcaatttct gatcctactt
     9781 cattgttcgt cggtgaatcc aatggcacag aaggatccat tacagcaaat tcttcatttt
     9841 ctttgatcaa ttgattagag aattcttttt cagggtctgt atctttgaaa gagaacgtca
     9901 cttcactagg acgagagctt gataacggtt gcacctcttg ttgccaaaga tccatatcga
     9961 taaattcgat agaaccatca tcattcaatt cataatgcgt tccttcgata ccgccagtca
    10021 tcaatttata cacatcttct tctaaaagat catcaacaaa ttgaagtaat ttcttcaatt
    10081 gtgcttcgtc ttttacttga gatttgggaa atgctagcaa gccgccaata ccatttcctt
    10141 ctgaccaaac atgataaccg ccgccttcac catctgagat cttgtttaca ggcactaatt
    10201 ccatatcatc ttgaatacct tgacccatcg tcttcagatt cttgatatcc accattccag
    10261 tgtagattcc agttcttcct tgtgcaaatt gttcttgctg atcagtcttt tgggtaactg
    10321 caaagtcttg tgccaaatag ccattctcaa atagatctct tgaaaaattc aaagctttca
    10381 tatactcttc tgtatcaaat tctggagtga atttgccatt atcgtctaca gcccagccat
    10441 ttggtgctcc aaaataagaa gtgaaaagtt taaagctggt ataacgaata tcactaggcg
    10501 cacgatcgcc aaaaccaact gtgtcgtcca caccatttcc atcaggatcg ttttctgtaa
    10561 attgtttagc tacttcataa agctcatcca tggtagttgg aacatctagt cctagattat
    10621 ccaaccagtc ttttcgaatg actaagccag cacgagcgta gtctttttgt atcggtacgc
    10681 cgtacaaggc accgtcgata ctcgcagctt cgattctatc ttcagaaatt tgacttaaat
    10741 ttttatagtc ttttaaatat tctgatacat cccagaatac gcctgatttt aacgcattgc
    10801 ggacagaaga gtttttcaac atcgcaattt gaagtgtaac gatatctcct agttcatcag
    10861 aagccaatgc agttgttaat ctttcttctt ttgaagcatc aggaatccag ttgaatgtca
    10921 gttccgtatc ggttttttct tcgatcaagt tcacaatcgt gtctgtaggc ggtgaagcat
    10981 gatgcaaaat atttaaccaa gtgattttag cttttccatc ttctgtctct gaagaactgt
    11041 tacttgaact gctgccgcat gcggcaagtg ctagaattcc tgcaaaacta agacctaatt
    11101 ttacgagcgt tgcttttttc ataaattttc tccttcactg ttttaataat atttttgttt
    11161 tcttctgttt tttctgtata tgagttcttc cattccaaat ggcaaaatat agaatttgct
    11221 gtccacgtga ctgcggaaaa gaagagactg ccaccgataa aggttaaaac acctggcatt
    11281 gtttggatga tcatcagata aatccctacc atacttaata tcaacactaa tgagtaatga
    11341 agatgtgaga atccgaataa aaatgccatt ttcattttga aaaaatatcc tttccaatca
    11401 taatgagcca tgattgggaa aatatagagt gctgagagca catatatgaa cgcagcaata
    11461 tacaaagcga tcctaagata ccaattgtgt atgaaagaaa gatccacaag taaaacaatc
    11521 ccgatggcgc catatatcca gctcatcagc aaggtttcac gatagttttc tttaaaatat
    11581 gtgaagtacg ttttcgtcaa aggaaacgtt tcttttgagc gcagccattt tctaatcact
    11641 gcaaccatcg catacgatgc aggaccgaaa gtaaaaactc ccaaacctgc gatgactaaa
    11701 ccgccccaca gaaaattcaa ataaaccaac tgtaaaatac gatttagcct tccgtttatt
    11761 ttatctaatg actgcagcat atctttccct ctctttctat cttagtaaac gccgtcttct
    11821 cctagctttt tggcaatctt attagctaaa attaccataa acaatcctac gaccccttta
    11881 aacaatccca ttgctgtact gaaacttaac tgtccattct tcaatccagc tgtataaata
    11941 taggtgtcga aaatttctgc aacgcttcga ttcaatgaat tcaataacaa gtacatatgc
    12001 tcgaacccta agtctaatgt ctgaccgatt tttagaatca gcaaggtaat gattactgga
    12061 cgaattgccg gcaatgtaac atgccatgtt ttgcgtaagc gtcctgctcc atccatttct
    12121 gcagcttcat acaactgtgt atcgactgca gttatcgctg aaaggtagat gatcgtagac
    12181 cagcccaact ctttccagat cacttgtccg atatatactg tgcgtgtcca ttcaggggat
    12241 gttagaaaac tgattttttc aaatcccatt gttgcaagga attcattcaa tacccctccg
    12301 tcaacattca aaaatacata agtaatcgaa acaatgatta cccaagacat gaagtgaggg
    12361 atgtaaatga tcgtttgaat cccgtttttc aatcgtttgt tcgttacttc atttaatagt
    12421 aaagacaaaa tgattggcat cggaaaaaac acgaagatat ttaatccgaa caagatcaac
    12481 gtatttctta ataatgtaaa gaatgtcggt tctgtaaaca aacgaatgaa atgtttgaaa
    12541 ccgacccaag gacttcccat tattcctaaa aatggttgat aatcttgaaa agcaataacg
    12601 agtcccccca taggaagata cctaaaaatc aagaaataaa ggactcccgg cagaatcatc
    12661 acatataaaa atttattcgt tttgattcct gcaattattt tttttcgtct tctgagcttt
    12721 tcttcttttt tcgatagcgt cagttgaaat ggttcttgtt tctttacact ttccataagc
    12781 ccctccttag ttttgtgaat gtttgctgct tatgacttca tgatagataa ctatctgaat
    12841 tacgtatata atcattttta ccgtaagtaa aaacgcttac atagcaatga tttttgtgct
    12901 atacaaaacg ataaagtgta ttttttcaca aataaactac gcatagcaaa ccttctattt
    12961 ttttctatct gacacttagc ataggaaatg attatatacg taatctttca ccgatgataa
    13021 attgaacata tagaaacaga aacatttaat ttattttgag gaggagccta tctatatgaa
    13081 aaagaaagtc tctataggag aaagaagttt tacacttttc aacaatacgt ttctaatttt
    13141 gctagctttg atctgtatcg ttcctttttt aaatatcatc gctacatctt ttgcttctac
    13201 acaagaagtc gtcgcgaaaa agtttatcct ttttcctact accttttctt tagacgcgta
    13261 tcgctacatt ctttctacgc cgaccatttt tagagcactt gctgtttcga ttggtgttac
    13321 aggtgtcgga acgatcgtca gtatgtgtgc aacttcactg atggcctacg gtctttccag
    13381 aaagtatttg tttggtcgag gtttcgtcaa ctttcttgtt gtattttcta tgttgttcag
    13441 cggggggatg attccaacgt tcttagttgt tcgttctcta gggctggtca attcttactg
    13501 ggccatgatc ctgcctgtgg ctgttaatgc aatgaatatg atcattatga gaaacttttt
    13561 ccaagccttg ccggatagtt tggaagaatc agcaaaaatg gatggttgca cagattttgg
    13621 tgtatttttc aaaattatgc tgccattagc gttaccgtct attgctacta tctcgctttt
    13681 ttatgctgtt acttactgga acacttatat gactgctatt ttgtatatca acgattcatc
    13741 taaatggccg atacagattc ttttacgcca aatcgtcatt gtatcaagtg ggatgcaagc
    13801 agaaagtagt gccgttgatg tgattccacc agcacaaaca gttaaaatgg ctgttatcgt
    13861 tattgcaaca gtgcctatgc tgattgttta tccttttgtt cagaaatatt ttgtcaaagg
    13921 agcactcgta ggttctgtca aagggtgatt atgtactgaa cgcaaaatgg tagttgtgtc
    13981 agaagtggtc agcttcaaga aataagaagg catttacgaa aattgcttct taaatttttg
    14041 tgaaatttcg gcttattttt cgaagaatct actcctggaa caccgtgtat cagaggttgt
    14101 gaaagagacg ttcagccttg agcgatgata aaaactctca caaacattgc gacgagtaac
    14161 ccacaggagc aataagaagc gattttgaaa aatagcttcc catatttcac aaaattatgc
    14221 cttattgtcg atagcctgtc tcttgaacgc catttattcg taaaaaagaa ctgtgacaag
    14281 acttttgtca cagttctttt tgcgtgctta gccttgaaat ttaactatcc ataaatacaa
    14341 atactagggt tattctaact tcttttattg cttgaatcag tccacaagaa aaacagcctc
    14401 ttgattcaca aatatttttt tcgatattct cccggcgtaa tcgattcctt ctttttaaag
    14461 aaacgaataa aattttgcgg atttcgatat tgcaatcttt ctgcaatctc ttttacggag
    14521 aggttagtct ctttcaacca tttttttgct acctctaaac gatgattttg aacaaaatca
    14581 ccaaattttt ctcctgtttc ctttttaaat acattactta aatagttagg gttataatgc
    14641 aacctatcag cgatcacatc taaagacaga tcacgatcat attctgtgta gacgatatgc
    14701 ataatattct ccgacaaatt tttaaattca tgatcagtga ttgcttgaga gcattctgtg
    14761 attggcagaa ctaattgttc taaaacaagt ttttctagtt ctttgggatg ataattgttc
    14821 agtgctttta cataaatttg tttcatgtta tcaaagtttt ttgaatctac tcccaataac
    14881 tgtcctaatt gaacgagttc attgatcaag cggaccgaaa ctacttcccg actcaaagga
    14941 tttttatttt gtgcaaacaa tgcatcaatc aattcatgta ctaaattctt cacttcctga
    15001 tttccagaac gaatggcttc aaacaatcga ttttgttctt ctatcggata tctaataagt
    15061 gttttttcat gagcagcagg aacgatttcc tgataaaaaa taattgaact tggaccagta
    15121 tttacacgat aatacagggc ttcttttgcc cgatcaaccg attgcttgct ttcattcagc
    15181 gtttcgaacc ggttactgat gcctatactg atagttaaat tcaagtattc ttttacacgt
    15241 ttttgaatga gtcggcaata ctccatgact tttttgcttg cttctgcatc atctttatcc
    15301 attcgataaa tagtggcttg catttcttca ttcaaaacga tcggcagcat tcgattttcc
    15361 tttggcacaa tttccgtgat catgttgttg atcgctaaaa gtagcaaatc acgctcccca
    15421 ccgtgactat cttctaacag atcgatttga accaaagctg tataatagca gtcattttga
    15481 gaactataac caaattgctg caaccgctga tctagttctc gcctttctac tcgatttcta
    15541 aataaactaa gtacaaatag cgtttccagc tgtggctttt gggtaactaa gtgtgcactt
    15601 aacgcttctt tttctcctat gatccgactg actgattgag cgaccaaatc tagttctttc
    15661 ccactgaatc cttttgattt aagattcaga cgttcctgta tttgagaaat cggacgggca
    15721 aatctgtccg aaaataagta ggaaagaaga ccaatgagtc ctaccagtgt taaagacact
    15781 gcaactagcc cgattctcag attgcggatc attgcgccaa ttgcactaga gtcaacttct
    15841 aatctgtaaa tccaattatt ataatctgat ttcagtacta tatacgtttt atctttttct
    15901 cttatcactt tcagctgatt gtaatctaga tccacgtccg ttaatacagt tggttgctct
    15961 ttatttttta ctgtctgagt agtaaaaagg ttgccaactt cgttttcaat agaaagtatg
    16021 tcttctccac tttcaccaac aacttgttct attgtatgtt tctctatcgt agcaattccc
    16081 aatgcatatt tttctttttc aaacattggc aaagaaatca ccatttcgat tcctttgttt
    16141 ttcttttgcc aaaataaatt atttttgtta tttatgtact tctgttgata cttttcaatt
    16201 tcctcttcgg tcagttgact caacgatcca ttgattactc cccatttacc agccaaactg
    16261 actaaatcat aattattatc atccataaca atcgtttcta taaaatttag ttctttcctg
    16321 atttcagaat aagtggagta atctgtatat gtcagcggat gcttgaatat gtccgagaaa
    16381 tttttggtcg aaccatacgt agaaaacgaa tattcaatcg ttctaatttt ccattcaacg
    16441 ttagttttaa cttgcctgag caaattcttt ttgtctgtta aataactcga ttcgatcgat
    16501 tcataggtat tctggtaaat gaataaacta aatcctatga caagtacggc tcctaataaa
    16561 aacatcggta aaaatatttt ataaaatact gtacttttct tcattttctt cctctcctcc
    16621 ttttaaaata aaaggctttc atttttctgt aaaattgata ctcatctaat taaatgagca
    16681 ttccccgctt tcaagaatag cataattaaa aataaaaatc caagtaattt ttaacgtgtg
    16741 caatcttttc atatcaaaga tctattgact tatcgtagtt atcgtaatat gatgaatgcg
    16801 ttaacaaaaa gtgaaaaagt aaggaaaatg atggaatggt aacgatcaaa gatgtcgcta
    16861 aagcagctgg cgtttctcat acgacagttt ctcgtgcttt gaataacagc agtttaataa
    16921 aaaatgaaac aaaacaaaaa atacgacaac tagctaagga aatgaattat tcgccaaact
    16981 atagtgcaaa aggtttagtg aatcaaaaaa aatatctaat cggactattt ttctcaagtt
    17041 tgcataaagg aacttcatca aatttcctag cagattccat tgcaggcatc cattcagtat
    17101 tagacacaaa ttacagttta tctgttgaaa gtatcgatgt tgttgattta acagaaatca
    17161 acctgcaacg ctacgatgga ctgatcgtta tgagtcaaag tgatgatgat cagcctttca
    17221 tcgactatct caaagaaaaa gaatttcctt tcgttgttgt caatcgtcac atcaatgatc
    17281 cagcggttat caacgtcact gccgatgatg cggccggtgt tatgcaggca gtagattacg
    17341 gtattggatg cggacatacg aagatcgctt atattggcgg aaagaaaaat tttcgttcga
    17401 caaaagaacg ggaaaaaggg gtattgaaaa gtctaaaaaa agcgagcatc cctgtcaatc
    17461 cagcctattt tttaacagga gattacagct tagaaagcgg cctccaaaac atggaatacc
    17521 tattatcact ttctgacctg cctactctgg ttttttgcgg caacgacgac atagcgattg
    17581 gtgcattgag agctgtacat ttagctggcc tccgtgttcc ccagaacatt tctctgatcg
    17641 ggttcgatga ttctccagtc gtctcctatc tcaatccgcc gcttaccacc gtacgtaagc
    17701 ctttgaaaga aatgtgtcaa gaaggaacaa agcttttact agatttgatc gaaggcagga
    17761 cgatcgaaca atctaaaatt gagctctcca ccttgttgat ccttcgtgag tcgatcaatt
    17821 acttgtaaac tacaagtaat tttatataaa aatgttaacg tgtgcataac acagaaagga
    17881 agtttatatg aaaaaactga caaaagaatt agtgaaaaaa aacgaagcac ctgtaaaagt
    17941 tcttcagttt ggtgaaggca attttatgcg tggatttatt gattggcaga ttcagcagct
    18001 gaataaccaa caattgttta aaggtaatgt tgcaatcatt caacctttag aacaaggtct
    18061 tggaaatatg atgaaccagc aagataattt atatacggtc attttacaag gactcagcaa
    18121 tggcgaaatc gttgatactt ccgagattat caccgtagta gaacaaatga tcaatcctta
    18181 tgatgaatgg gatgcttatc tatctctagc agaaaatgac gacttggcct atatcgtctc
    18241 caatacaaca gaggcaggaa tccaattcgt ggagactgat aatttaacag atactccccc
    18301 acagagcctc ccgggcaaac tgacagcctt tttataccga cgtttcaaat taaacaaagc
    18361 tggctttacc atcattcctt gcgaactgat tgacagaaac ggcgaacgtc taaaagaaat
    18421 cattttacgc tacgcagaaa aatgggattt agaacctgct tttgttgagt ggttagaaaa
    18481 agaaaatgtt ttctgttgta gtttagttga tcgcatcgtc ccaggttatc ctcgcgaaga
    18541 tgcaggtgtt ttcaatcaac ggcataacta tgaagatcaa ttgatggtca aagcagaacc
    18601 attcatgctt tgggtgatcg aagggcctaa agaattggag aatcaactac cattcaaaca
    18661 ggctggcttg aatgtcatca tcacagatga tatgactcct tatcgtgaac gtaaggtgca
    18721 tttgcttaat ggaccgcata cagcgatggt ccctcttgct ttgttggcgg aattggaaac
    18781 tgtagaagaa gtaatgaaag atcctttatt ctccgcatat gttgatcagt tattcaatct
    18841 agaattgatt cctatgcttt ctttacctaa agatgaatta gccatttatg ctgaccaaat
    18901 caaagaacgt ttcttgaatc cttttgccca tcacaaatta gaagcgattt cattaaatag
    18961 tgtttcaaag ttcagcaccc gtctgcttcc agtgttcaag aagtatatcg aagaacaaaa
    19021 tcaggtacca ccgttaatca ctgtttcact agctgcgcta cttcttatgt atcgaggcga
    19081 tcaagtaaag ccacatgatg atgaaaagac gataagcgaa tttactgatg cttggtctga
    19141 taatggaaca gctattcctc gattattgca aaacgctgcg ctttggggag aagatttgtc
    19201 tcaaataccg aatgtgacag atacagttca agaaatagct gcaaagatcg atcaaaaagg
    19261 tgtccggtca gtattacaag aaatgaaagg aacgatggtc catgcttgaa accctgcaac
    19321 caacaatgaa attaaatcga cgagacagtg tggtcgtcgc attaacccct attccaaaac
    19381 aaacacaact gacgattgat cagcaaacga tcaccactct tgaagatatc ccgcaaggtc
    19441 ataagattgc attgggtgat ttgaaagctg gagacaacgt gatcaaatat ggctatccaa
    19501 tcggtcatgt gacgacagac gtaactgccg gtcaatggct gcacactcat aatgtaaaaa
    19561 ccaatctttc tggtgaattg gattatcgat atgaaaaaga tgtccatcca agtcattacc
    19621 tttttgagaa ccgaacattt caaggttact tgcgaaaaaa tggaaaagta gggattcgta
    19681 atgatttgtt tttagtacct accgttgggt gtgtgaatgg cattgctgaa ctgatcgtca
    19741 aacagttcaa ggaaaaacat ccagatctgg gacagtttga ccatattacg attttaaagc
    19801 atccttatgg ctgttcgcag cttggaaaag atcatcaaaa tactcgagaa attttagcgg
    19861 acgcagtaaa tcatcccaat gccggaggag ttttagtatt tggattaggt tgtgagaaca
    19921 atacagttcc tgaattcaaa aaaattttag gtgaatatga tgaagaacga gtgaaatttc
    19981 tagtggctca agatgtttac gatgagatcg aacaaggtgt ggctctatta gaagagcttt
    20041 taacagcggc ggaaaatgac cagcgcatat cagtcccgct ctctaagttg aatgtcggtt
    20101 tgaaatgcgg cggttctgat ggtctatcgg gaataactgc taatccttta cttggtgcat
    20161 tttctgacta cttgattgct caaggaggca gcacgatctt aacagaagtg ccagaaatgt
    20221 ttggcgcaga acaagtattg atggcacgag cggaaaatga agaagttttt gactcaatcg
    20281 ttgacttgat caatgacttc aaacagtatt tcttgtctta cggggaacca gtttacgaaa
    20341 acccatctcc tggtaataaa gcaggtggga tcactacatt agaagataag tctttaggct
    20401 gcacgcaaaa atcaggaagc tctcctgtcg ttgatgtgct acaatatggc gaaaaaatca
    20461 gaaaaccagg gcttagttta ttgcaagctc ccgggaatga tcttgtagct gcctctgctc
    20521 ttgcttcatc cgattgccag ttggtcttgt ttaccacagg aagagggact ccgtttggct
    20581 catatgtccc aacggtcaag gtatctacga atacaactct ttttgaacgc aaaggtcatt
    20641 ggatggattt taatgcaggc gtcttattag aacaaccaat ggaagtaatc ttagaatcgt
    20701 ttgttcaaaa aatcatcgct gtagctagtg gagaagaaac gaaaaatgaa caaaatgacg
    20761 ttcgagaaat tgccattttt aaaaacggag taacactttg attttcataa aacagtataa
    20821 aaagaaagaa ggaagattta tgtttttatc tgatgatttt ttattaaaag acgattgggc
    20881 gaaaaagctt taccattcct acgcaaaaaa catgcccatt attgattatc actgtcactt
    20941 agatccaaaa gaaatttacg aaaacaacaa tttcagcaat ctgacagaag cttggttagg
    21001 aggcgatcat tacaaatggc gcttgatgcg agcttgcggc gtgcctgaag aaaaaatcac
    21061 aggaaatgct tctgattttg aaaaattttt agcttggtgt caaaccgtac caaaaattat
    21121 cggaaatccg ctttacagtt ggtcacatct tgaattgaag cgtttcttcg gtattgactt
    21181 gttgataaat gaagaaaatg cagagaaaat ttggacacaa gcaaatgaaa ttttggcagc
    21241 tcctgatttt cgccgtcggg aaatcgcaaa aaaatcgaat gtagaagtga tttgtacaac
    21301 agatgatccc gcagacgact tgcactatca tcagttgctt gctcatgaag aaccagattt
    21361 gaaggttcta ccttcattcc gtccagataa agcactcaat attgaaaaag aaggatttaa
    21421 tgcatgggtc acactactgg aagaagcagc tgaccaaacg atcaccacct atcaagaact
    21481 gatagaagtc ttagggcagc ggatagaata cttccatcaa catggatgtc gtgtttccga
    21541 ccacgcttta gacatcttac gctataaaga agcggatgaa acagtattag aagagatttt
    21601 tcaaaaagca cgagctaaca aactattatc ttcagatgaa atcgatgctt atcgtacaga
    21661 aacactgata catttgaccc acttctatca ttctcataat tggacgatgc agctgcacat
    21721 ccatgcttat cgtaactgta atacacaaat gttggaaaaa ttagggcccg ataccggcta
    21781 tgatggaatg aatgatcttt ctttgactat tcctctgcaa aaattattga accgtgcaga
    21841 agaaacggat cagttgccaa agacgatcct ttattcattg aatccgaatg actatcctgc
    21901 gattttagct ttgatgggct gtttccaaaa agaacagaat ggaaaactgc agttaggttc
    21961 tggatggtgg tacaacgata ctcgagctgg tatgcgcgat caattgacac aatttgctga
    22021 tggtagtgct ttggggaatt ttgtcggcat gctgacagat tcaagaagtt tcctgtccta
    22081 cactagacat gaatatttcc gtcgtgttct ttgtgaattt ttaggcgaaa tggtcatgcg
    22141 aggagaagca cctgaagatg aacaactttt aggaagtcta gttcaagcga ttagttatac
    22201 aaatgctaaa aattactttg gcttttttgc ctaattgatt aatagtaaca gtaacgaatc
    22261 aaaaacagga tagtgaaata acggaatccg tttatccacg ttttagagaa gaagacggac
    22321 caaatttgct ccgtcttctt ctcttgctgt tctgcttcat tgcctataaa cctttatgaa
    22381 agaagagata acatgcctac tatccatatt gccggtgatt ctactgcggc agaaaaagat
    22441 gaaaacaagc gtcccgagac aggttgggga gaaaaaatct ctgcttattt ttcacccgag
    22501 atccagatca ataaccaagc aaagaatgga cgcagcacca aatcatttat ccaggaagga
    22561 aggttagccc gtctagcttc acagtttcag ccgaatgatt tcttatttgt acaatttgga
    22621 cataacgacc agaaaatcca agaagaaaga ggtacgcttc ccttcggtag ctatttaaaa
    22681 aatctgcaga tattttttga atgcgcaaaa aaagcgaacg tccaaatggt cttactgaca
    22741 tctgtgacgc gacgagatta cttagaaaac ggaacattga atccagatat acttggagac
    22801 tatccaaaag cgatgcgtgc atttgctgag aaacaccata ttcctctttt agatgtgttc
    22861 tcaagatcac aagaattgtt ccagaccttc tcaaaagaag agacaaaaaa attctacctg
    22921 catcttatac ctgatacttg taaaaattac ccagaaggac taaaagacaa tacccacttt
    22981 agtccagaag gcgctgataa agttgcccga ataattgttg aattgataaa agaatcccgt
    23041 ctgcctcttg ctaattattt acaaaaagga gtttgagatg tttccattaa atttaggcat
    23101 ccgtgcccac gatttagatg ttcgaaatcg tgaagaaatc gttcaaaaag tatcacagct
    23161 tcacttgtcc catatccaat ttgcaccaca aaaagcattt cctgaacaac ttaaattaac
    23221 tgacatgaca cttgggagtg ctgcctattt tggtgaatac ttccaaaaaa acaatatcga
    23281 actttccatt ttaggatgct atatcaacct atccagcaaa aatcaagaag ttcgtgcaca
    23341 agcattggca actttcaaac agcaaattgc tctgtgctct gcctatcaag ccaagatgat
    23401 tgctacggaa accggtagtg tctctgtcgg ttacacaaaa gaaaatttta ctgaagaagc
    23461 ttatcagatc gccagaaatt ctatcattga attagtcgct catgcagaaa attttggcgt
    23521 aactgttgct gttgaagcag ggatcaatca tccaatctat aactatcagt tagctaaacg
    23581 tttaatcgat gaagtagctt caccaaattt aaaaatcatt ttagattgtg cgaatttgat
    23641 gcataaagaa aatcatgctg atcaggaaaa agtgatccga ggtgccttgg acaatttaca
    23701 tggttatatt acagcgcttc atctcaaaga ctatatcatg gaaaatggaa agatccgcat
    23761 ggtacctgtt ggcaagggct gtttagattt ccgcccggta ctgcattata tcaaatatga
    23821 gcgtcctcta atgtacgcca ctcttgaagc tactcctgag atttatgttc ctgaagcaat
    23881 agaacacttg cagtttattt accaagattg ttaaggagaa gattatggag gaacgaatac
    23941 agaaaagtta tcaaaaatat catgcaaatg cttttcagac attgctgcat ctttatcagg
    24001 gaaattattg gcgttttgcc atgtcaggac tcttttttat tatcaaacat cttccatctt
    24061 ggttaatgcc gatcgctatt gccaatgtaa tcaatgcagc ttcatcgaaa gattcttctc
    24121 agttgcaggc catttatttc aacgcttttt tgatggcttg tctgattggt caaaatatat
    24181 tgacgaatta ttttcatgta aaataccata gcacttcgat ccgtcaagta gaagctggac
    24241 taagagcgac ccttatcaag aaaatccaag aactatctat tccttatcaa aaagaattgc
    24301 aatctggacg aatccagtca aagatcatcc gtgatgtaga agctatccaa acgttgtcct
    24361 ctcaagtatt tgtcagcgga ttaaatatcg ctgtcaattt attcgtagct ttaggtatca
    24421 cgctttataa aagtcctgtt gttttcatgt ttttcttatt gactgttcct ctcgccgcat
    24481 tcgttactct ctttttccgt aaaaggatca gacagtccaa ctcagacttc aggcaagaaa
    24541 tggaagagac ttctgcaaaa gtgatcgaag tgatcgaatt agcaccgatt gctcgagctc
    24601 atgggttaga aaaacacgaa acaactcgct taaataagca ttttactcaa atctatgaaa
    24661 aaggattcca cttagatatc ctgcaatctg ttttcggatc agtcagctgg gctagttttc
    24721 agatatttca gctgatttgt ttgattttca ctgggatatt agctttacaa gggcgcatcc
    24781 aacccggcga tgtcgtgatg tatcagacgt atttcacgac gatcgtcaat tccgtttctg
    24841 gaatgatcac gctgattcct acgatttcaa aaggcatgga atctatcact tctattggcg
    24901 aactgttgat tgctggcgat gtagaaactt atcacggtaa gaaaaaaatc caacatttgg
    24961 atggaaattt tcgttttgag gatgtttctt ttctttatcc ggactcactc aaaccgatta
    25021 tcgatcattt ttctctagag gtgaaagctg gagaaacaat tgcttttgtt gggccatctg
    25081 gctctggaaa atctacactc cttaacttat tgattggatt tatccagccg acttcaggaa
    25141 aaatttttct agatgatcag cctttggatg aactggatat gcgaagtgtg cgaaattatt
    25201 tagccgttgt tcctcaaacc actttgttgt tctccgcttc gatcaaagag aacatcactt
    25261 atggcttgaa aaacgtatca aaagaacgtt tagatgaagt catcgaagct gcgcaacttt
    25321 cttcactgat tgaccagctt cctgatggtc tggatacctt agtaggcgaa catggcaaca
    25381 agctgtctgg tggccaaaag caacgtatct ccattgcacg agcgttgata cgtcagccaa
    25441 aaatcatttt gctagatgaa gcaacctcag ctttagataa ccagtcagag aaaaaaatcc
    25501 agcaagccct gaattacctg acagaaacac ccactacttt tattgtggct catcggcttt
    25561 caacgatcaa agaggcagat aaaatcgttg tgatcgatga aggaaaaatc gttgaaatag
    25621 gtacttacga aaaactgtta gctcaaaaag gctatttcta ccgcttgaaa aatgaatgac
    25681 aaaaaatagg agctatgaca agacttttgt cgtagctcct atttctgaat aaacggtgtt
    25741 ctcctgccaa ctcctcggtc acaagtcaca atagtcatca aacatgagaa gctgtttttt
    25801 gaaattgttc cttgtaactc agagttaaac ggtaggctca cgacctcttg gtaaatggtg
    25861 ttcaagagac agcctatcgg caataagaag caattttgtc atcgctcaag gccgaacgtc
    25921 tctttcacac cctctgttgt ttcataaaat agttttattc gctgtaaagg tcgcgaactg
    25981 gtgtcatgat gatacggttc aagtcattga tgattgtact gaagccttgc tctttttgca
    26041 tcaagtcatt gattacttct tctgattgga ttttcacagc catttcttgt gctttcattg
    26101 catcttcgtc gctgaactct tgtccactca tttgtttttc ttgtaattcg atttgcatcg
    26161 cttggaagtc tttgaacagt ttgtgtgctt cttcgtttgc ttgtactttc tcgtacgctt
    26221 ctttcaacgc tttgaattct ggtaattcac ggatctcacg ttcgatttga ttcgcgctat
    26281 cgtagatgtt tgacatgtta tgccctcttt tcttttagta gttactctct attgtaacat
    26341 ggggttattc gttttcaaag gggctactct ccttgatatt tccgccagag gtctttagcc
    26401 gcttcaccaa ttccctgaac gccttctttc accatatcgc cgaagttttt cagcccttct
    26461 tttgcttgtt caccatattg attcaagtta tcttgccaat ttccagactc tccattagaa
    26521 tttcctgtgt ttccaacttg atctgcagct accacttgtc ctcctgtggc ataggcatct
    26581 gctacactaa atcctgtttt tgaagtatac ggaaggatgc cttctgccgc tgatttgaag
    26641 actttcccga caacatttcc acttgtccct tccaaatagt gcagcttgct ggattcttcg
    26701 taacccatcc atgtcgaaat cactacgtct ggcgtgtaac cgatcatcca ttggtcattt
    26761 gcttttgtgg catcgaaatt agtttctgtg gttcctgttt tccctgctat cgtataacct
    26821 gcaggattcg cagcagccgc tgttccattt gaaaatgtac caagaagcat gctggtcatt
    26881 tcatcggctg tttcctttga tatgacctgt tttggttttt tgtttgtgtt atcgacgatc
    26941 accgctccag tcgaatcaac gattttcgtg ataagatgcg gcgtatacat ctgaccatca
    27001 ttggcaaatg cactgtaagc acccgccatg atcaatggag atactccttt ttccagtcca
    27061 ccaagggcta agccataata cttatcagat tttgctaaag gcaggccgaa ttcttctgct
    27121 ttatcatatc ctttttgtaa accgatctca tgcaaaagcc atacagtagg caaattcaaa
    27181 ctttgtgcaa cagcttgata catcggtact tctccttggt atgtcccgtc aaaattatgc
    27241 gcatcgtaat aactttgcgg ttcgtctttc aagatactgg aaggcttgta tccagcttcc
    27301 agtgctggtg tatatacgct taatggtttg atcgttgatc ctggtgaacg acgcatctgt
    27361 gtagcaaagc tgaatcctct aaagacatga tctcctcttc gtcctactag tgcttgtaca
    27421 ccacctgtat tcggatctaa agctactgaa gcagattgga ccatggcacc atctgaagca
    27481 tttgctggga ataatgcact gttttgataa gtagcttcta attgcttttg ataatcctga
    27541 tctaaagctg tatagatttt atagccttta ttcatgacat cttcttcatc aagaccatac
    27601 tcgttaactg cttcatcgat cactgcatca aaataataag gataacgata accagaatct
    27661 gaattatcgt atgtgtcatt aagatacgcg ctgatatctg tctggctttc tgcttgttct
    27721 tgttcttttg tgatttttcc gttttcttcc attacactta gtactgtgtt tttccgatca
    27781 ttcgcatttt ttgggtgatc gatcggatta taaataccag gacctttcag cattcctgcc
    27841 aaagtagcag cctcagacag cgtaacattc gttgcatcta ctccaaaata ctttctggaa
    27901 gcgtcttgga caccccatac cccgttgcca aaataggcat tgttaagata catggtcaag
    27961 atttcttctt tgctgtactt cttttcgatc tcgattgcca aaaataattc cttcgctttt
    28021 cgatcaaacg tttggtctaa tgtcagatac gcatttttgg caagctgctg agtgatcgta
    28081 cttcctccgc cccctgatgt tccgccagac aagaccattc ggactgctgc acgggcaatc
    28141 cctttgatat caaacccgtg atgctcgtaa aaattcctat cttctgtcga gattactgca
    28201 tcttggatat agggagaaat cgcgtttaat tctacatatg ttcctttttg ggcgtacagt
    28261 gtgccagctt cttcgttttt cttatcataa atgactgtcg attggcttaa tcctgatttt
    28321 aacgtttcga catttgcttg ttttgctaaa ataaagaggt agatacttgt cactaagaca
    28381 cagatcaaac caatcagcaa aatcaatttg ttcacatgat attttttcca gatgcgcttt
    28441 cgccatcgat ggaattgtcc gagatatggt ctgatccaac gccaaaaact gatcaaagca
    28501 gcttttatct tttctaaaat gctttgaaaa tccatttgct tcttctcctg tctatttgat
    28561 tcaatcgtct tattttacca tagtgaaaga gtgttttctt cctgcttaag ttgtagttca
    28621 atatgttttt ttacgttagt gcaagtagag taacataaga atgaacagaa aaatgtaagt
    28681 tttttcttaa atatgtttta aaaatggtac aattagtctg cgattgcact gaaaggagta
    28741 cacttgtgaa aatcacgatc actttaccta tgaaccatcc tgaaacaaca attcgcgact
    28801 tgcttgaaaa ggaatggtta gttcctagaa aggttcgaca ctttttgcgt atacgtaaaa
    28861 acgtttggat caatcaacaa cctgctttgt tccatcatga agtaaagggc aatgaccaga
    28921 tcacattgtt attcgaagaa acagattata attatcaaga agttcaatta ggagatgcga
    28981 agcacatccg tgttttatat gaagatgagc atttgattat agtggataag cctgcaggaa
    29041 tgaagactca tccaaatgaa ccgacagaaa acagtacctt actcaatcat ttagctgctt
    29101 atctcgacac taaacagcaa cgaccttacg ttgtccaccg cttggacaaa gaaacaagcg
    29161 gtgccgtttt atttgcaaaa aatccatttg tcttgccgat acttggaaga atgttggaac
    29221 aaaaaatgat ctatcggaga tatcaagcca tcgtatgggg agaaattgcc aaagatatga
    29281 ccatcaccaa taaaattgga cgagatcgcc atgatcggag aaaaagggtc gtagatgata
    29341 aaaatggtca gagcgccttg acacatgtca ctgtcaacaa agtactttct gaacaaacac
    29401 aagtctattg tgttttggaa accggacgta cacaccagat cagagttcat ttagctcata
    29461 agggacatcc gatcgttgga gaccctctct accaaaatag aacagctgaa cgactgatgc
    29521 tccatgcatt agaactgcac atgatccatc catttactca agaaaaaata gtcggtaaag
    29581 ctttacctgg attatgggaa tagaaataaa aaagaacaga gtcttatcag cagataatga
    29641 taagactctg ttctttttgt gtaatttgtc tgcttacttt tgatgttcgt gttctgctaa
    29701 cagcaaacta ccgataatcc cactttcatt cggcagtccc caacgaacga tatattcact
    29761 tacttgaggt gtttccatat aaccacccat caattcaaca aattgctgac ggattttttg
    29821 aaggagatga tcctgattca ttaccccacc gcctaaaata atcttttcag gtgctaacgt
    29881 caacgtatag ttgatcagtg cttgagcaat ataataagcc tgaatagccc aaacaggatg
    29941 atcttgcggc agatcttgcc ctttgatccc tgtgcgtgcc tcaatagacg gtcctgctgc
    30001 taatccttct aaacaatctt tatgataagg acaagtacct tcataatggt catctggatg
    30061 gcgtttcacc caaatatgtc ccatttcagg atgtgcgatc cctgaaaaaa tttcttcatt
    30121 gatcacgaca cctgcaccga ttcctgttcc cacggtaagg taaatacaac tattttttcc
    30181 ttgtgctgct ccttgcttca attccccata tgcagcagca ttgacatccg ttgtccaagc
    30241 agcaggaata ttgtagcgtt ccttgattgt gccaagaaaa tcgaattgtg cccacccttt
    30301 tttgggagtt gccaaaacgt atccgtaatt atcttttgtt ttgtcgatac caatcgggcc
    30361 gaatgagcca atcccgattc ccttcaattc ataacgatca aaaaattcaa atacctgatc
    30421 caatgtttct tctggtgttg tggtagggat acttaatttt
//
LOCUS       DADLIO010000028        29079 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.028, whole genome shotgun sequence.
ACCESSION   DADLIO010000028 DADLIO010000000
VERSION     DADLIO010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29079)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29079)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29079
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.028"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            68..808
                     /locus_tag="JOX41_001417"
     CDS             68..808
                     /locus_tag="JOX41_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAY6449169.1"
                     /translation="MTKANRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGL
                     TTGADGKLAIDGLAPGVYQLVETQAPTGYELDATPIEFEIERSQTAVVELTKENRLTP
                     GGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGAYQLVET
                     QAPTGYELDATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPTSSGNKHLPKTGE
                     TIISQFILSILGVLLVFISIKFRKKRNI"
     gene            complement(1232..1402)
                     /locus_tag="JOX41_001418"
     CDS             complement(1232..1402)
                     /locus_tag="JOX41_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAY6449170.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(1596..1775)
                     /locus_tag="JOX41_001419"
     CDS             complement(1596..1775)
                     /locus_tag="JOX41_001419"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449171.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            2162..3274
                     /locus_tag="JOX41_001420"
     CDS             2162..3274
                     /locus_tag="JOX41_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAY6449172.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            complement(3352..3645)
                     /locus_tag="JOX41_001421"
     CDS             complement(3352..3645)
                     /locus_tag="JOX41_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HAY6449173.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            3813..4127
                     /locus_tag="JOX41_001422"
     CDS             3813..4127
                     /locus_tag="JOX41_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HAY6449174.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            4148..6127
                     /locus_tag="JOX41_001423"
     CDS             4148..6127
                     /locus_tag="JOX41_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAY6449175.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            6140..6466
                     /locus_tag="JOX41_001424"
     CDS             6140..6466
                     /locus_tag="JOX41_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HAY6449176.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            6482..7000
                     /locus_tag="JOX41_001425"
     CDS             6482..7000
                     /locus_tag="JOX41_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449177.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            7000..8352
                     /gene="celB"
                     /locus_tag="JOX41_001426"
     CDS             7000..8352
                     /gene="celB"
                     /locus_tag="JOX41_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAY6449178.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(8436..9941)
                     /locus_tag="JOX41_001427"
     CDS             complement(8436..9941)
                     /locus_tag="JOX41_001427"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HAY6449179.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(10033..10623)
                     /locus_tag="JOX41_001428"
     CDS             complement(10033..10623)
                     /locus_tag="JOX41_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAY6449180.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            10802..12448
                     /locus_tag="JOX41_001429"
     CDS             10802..12448
                     /locus_tag="JOX41_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAY6449181.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            12497..13216
                     /locus_tag="JOX41_001430"
     CDS             12497..13216
                     /locus_tag="JOX41_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAY6449182.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            13695..14642
                     /locus_tag="JOX41_001431"
     CDS             13695..14642
                     /locus_tag="JOX41_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAY6449183.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            14654..15574
                     /locus_tag="JOX41_001432"
     CDS             14654..15574
                     /locus_tag="JOX41_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAY6449184.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            15615..17072
                     /locus_tag="JOX41_001433"
     CDS             15615..17072
                     /locus_tag="JOX41_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAY6449185.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            17417..18031
                     /locus_tag="JOX41_001434"
     CDS             17417..18031
                     /locus_tag="JOX41_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAY6449186.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            18024..19748
                     /locus_tag="JOX41_001435"
     CDS             18024..19748
                     /locus_tag="JOX41_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAY6449187.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            19745..21196
                     /locus_tag="JOX41_001436"
     CDS             19745..21196
                     /locus_tag="JOX41_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAY6449188.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(21669..23822)
                     /locus_tag="JOX41_001437"
     CDS             complement(21669..23822)
                     /locus_tag="JOX41_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAY6449189.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(23824..24870)
                     /locus_tag="JOX41_001438"
     CDS             complement(23824..24870)
                     /locus_tag="JOX41_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAY6449190.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            25020..26309
                     /locus_tag="JOX41_001439"
     CDS             25020..26309
                     /locus_tag="JOX41_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HAY6449191.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            26322..29024
                     /locus_tag="JOX41_001440"
     CDS             26322..29024
                     /locus_tag="JOX41_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAY6449192.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
BASE COUNT         9454 a         5025 c         5898 g         8702 t
ORIGIN      
        1 ggggtatgaa ttagatgcga caccgatcga gtttgagatc gaaagaagtc agacagcggt
       61 ggtagaattg acgaaagcaa accgacttac accaggcggt gtcgtgttga caaagatcga
      121 tgaccaaagc ggggaagtcc tgcaaggagc tgtttttgag ttacaagatg ccaatggaac
      181 cgttctgcag tcaggtctaa ccacaggagc agatggaaaa ctggcgattg acggcttagc
      241 accaggagtg tatcagctgg tagaaaccca agcgccaacg gggtatgaat tggatgcgac
      301 accaatcgag tttgagatcg aaagaagtca gacagcggtg gtagaattga cgaaagaaaa
      361 tcgacttaca ccaggcggtg tcgtgttgac aaagatcgat gaccaaagcg gagaagtcct
      421 gcaaggagct gtttttgagt tacaagatgc caatggaacc gttctgcagt caggtctaac
      481 cacaggagca gatggaaaac tggcgataga tggcttagca ccaggagcat atcagctggt
      541 agaaactcaa gcgccaacgg ggtatgaatt ggatgcgaca ccagtaactt tcaagatcga
      601 aaaagaacaa gaagtggcga tctttttaac aaaagagaat agaaaagttg ctgatagctc
      661 agatataaga ggaaacaatc caacaagcag tggaaataag catcttccaa aaactggaga
      721 aaccatcatt agccagttta tattgtcaat attgggtgtg ctacttgttt tcatcagtat
      781 aaaatttaga aagaaacgaa atatatgagc taaaataaaa aattgaataa gcatagtttt
      841 taaaatcaac tagtacccat caattgaatg gaaactaccg attttagaag gggtatacaa
      901 acaaatatta gtatcggagt agagaaggtt gaacccaacc agtaaataag taaagacaat
      961 tttgtgctgc gttgagaagt gaaaaataaa cctttgtagt aatactagtt aataaaaaat
     1021 atacaaaaac actgcgaaaa tcattcttga gtttcgcagt gttttttgcc taatgactca
     1081 agtttattgg gtaatacttt gattttcttt ctacaaataa tcagcgatca gttgtaattt
     1141 tttctctagt tttaatggct ctttgtcaat aaggagaaaa acaagtcggg tcttttgtct
     1201 cggaaagctt caaccaactc gtgaataaag gttacgcctc cttgaaaggc gtggaaaaac
     1261 caagtaatcg atcaatcacc aatttcgcat ttggtagaac atgtttggtg agctgaaagt
     1321 aggtggcgtt catgtctgta actaagaatt ctatttcttt aggattagtg cagctaagga
     1381 aatagtttgt taatcgagga attttttgtg taggtaaatt ttctcgatta atttttctgt
     1441 ctcgccatcc gcggaaataa aactcagttt atcctcaacg gaaacgtgag aacgaaattc
     1501 acaaccctca acactcaaga cagaattctt ttggaagact ttggtaaata gcttctcaac
     1561 tctttcaatg tgcgaataac ggttgtcaaa gatacctaac aacttttcga aataaaaaat
     1621 aacgacactt tttcagtcag taaagaagtg attttatgtc tgacatgatt tgaaatcgag
     1681 tgccttggac ggataaaata actttgagcg ttccaatggc ttcgacagtt tttacaggta
     1741 tagcgctgct tttttaggcg tataaccatt ggcatatgat tatattattc aaagtggaca
     1801 atggtttcct tcttcttgtt tttcaccacc attaatttcc tatttccatc taccacagca
     1861 gaaccacaat ttctacagac acatggagca gggaagagaa ctgcagcaac gatcaatgtt
     1921 tttttcttct gtaaggtttc gtaagagacc tctgtaatca tcaaattttt gtctattgat
     1981 ctcagaattt ttttgataga accattcata aagcatatcg ttctctcagt tgtttatttt
     2041 gtggtgattt aatcatacaa gaaaacgata tgttttttta taaaaacatg aataggaaaa
     2101 atagttgaca agaaaatgac aacgccatat gatgttccat agtatttaca acctgtcata
     2161 gatgactgta aaaaataaaa gtaaaaagaa aggacgacaa caggtggatt tttatcagtc
     2221 tctacaacta gatccgttta ttttaaaaca aaaaatacga gaagcagctt ctaaaaaaga
     2281 aaagtgcatg tatatttgtt cattgttttt acgatcatta ttcatcgtat tgtttgccat
     2341 ttgttttatc attataatta caacattatt tgaatcgaag cataaaccat acgctgtggt
     2401 tttattctgt atgttgatga gtattcgttt tgttgacttt ggttataaga tttcccattc
     2461 gatcataggt ttagcaatcg tcatgttctc actattagta gcaccgtatg tccagctgat
     2521 caaatggtca gttatgggca tgttgattca ttttatttta ctaagcagca tattaatggc
     2581 aaccgctagt gatcccaaaa tggggaatgc ttctttgtac ggcttttcat atctctttat
     2641 tgtttattcg ttacctaaag attcgttgaa caagaatttc tttacacaaa caagtagctt
     2701 attatttttg tttttttgtt ggttttcagt tctcctttac agaaaacatc gagaaaagaa
     2761 caaagacaaa agcttgttta aagagatttt tttgaaaggc atgtattcgc aggaaaaaat
     2821 ttggatgctc atctatgcat ttggcattag tcttttgatc gttgcaggag agtatgtccc
     2881 ttttcagcga ttgatgtggg cagggtttgc attttcttct attgtatcta gctatggatt
     2941 gatgtcgatt ggtttcaaag aacgagcagt agaccgaatc attggctcat tgattggatg
     3001 tgttttattt attggtatca gccaatttat tccttttaac tgggtcggta tattaggtgg
     3061 tctagcttta ggtgtttgtt ctacctatag atataaaaca gtttttaatt cttttggtgc
     3121 tttggcaatc actgccagtt tattcggggt tccaggagca gtaacgatcc gcatttttga
     3181 gaatatcctt ggggtatgtt taggaatcat gtatattggg gtgactgaaa tacttatccg
     3241 aaaaataaga gaaaaacacg gtttgaatca ttagatgaga tcgaataaaa aataaggaaa
     3301 aagtgaagat acacatggat gataaattgc tatcattcca tgtgtatctt tttacggtaa
     3361 atcagtgaaa cgttcgactt tcatttttaa tttatacttt ttacggagtt cgtttatttg
     3421 agccatcatt tcggatttgt gatgcttttc gattgcttct tcatctttcc aacggtcgat
     3481 cagtaaaaga gattctggat cttctagtgg aaagtaatag tcatatttct cgtttccttc
     3541 ttctgcacga atcgctttga caatgtttct ttcgaccatt tcttctgcaa attttctggc
     3601 ttgtccattt gtacttgtat acaaaatatt cactgtgata ctcactaaat cccctcctga
     3661 aaaaattcta tcactagtat atcacggtgc cagaaattat tattcaagat atgatacaca
     3721 ttttttccgc aatgctacgg aaatatatat tttgaataga aaacgcttac aagatatgct
     3781 tggtttataa aaataaaagg agtgattgat ttatgaaaaa agcattgatt atttgtgcgg
     3841 caggaatgtc atcctcgatg atggcctcaa agacaacgga tttctttaag caaaaaagag
     3901 aagaggtact cgtagatgca gtttcagcta cagaaggcga taatatgatt aagaatagtg
     3961 attttgattt atttctgatc agcccgcaaa cgacgatgtt tttggataaa ttcaaaaaat
     4021 taggagaatc tgttggaaag cctgttgtta gtatcccttt ccaagcgtat gtcccaatcc
     4081 ctacaggcat ccagaagtta gcagaggtga tcgaagagaa catatgatgg aataggagtg
     4141 gatgataatg aaacagaagg aaaaattgct gttgagatat ttgattgatc acaagaagga
     4201 gtatgtcacc agtcaacgtt tagcttctga attgttatta tctgatcgga caatccgtaa
     4261 ttacttgcag cggatcaaag agttagtaga aaaaaacgga ggtaagatca ttgctaaacc
     4321 aggttatggc taccaactgc atattttaca aagactgaca tttgacttgt ttttgagtcg
     4381 gcaagaaata gtacctggat atgctagaga accgcaagga ttttatgagt ccgaagatcg
     4441 acaaaagtat atattgaacc aattgctttt ggaagatgcc attcttttta tggatgattt
     4501 ggcagaagag ctttatatca gtcgttccag tttgacaaag gacatgcaag aaatcaagga
     4561 gcgattgatt ccatattcac taaaaatcgt ttctaagcat ggtcaaggga catggatcga
     4621 aggggaagaa agaaatcgac ggcattttat catggatact ttttttggaa accattatgg
     4681 aaattcattg aaagaatatt tagggcaaag ccgttttttc ccagacatca gttttgaaga
     4741 gctagtcatt atcattctcg atgaaacaag agaagctaag ttaaaagttt cggattttat
     4801 catacagaat ctgactttac acttggcttt ggggatcaaa cggctccgag aagggtttga
     4861 aatcaaggaa ttaggcatcg aacaagaagt ttctaagcga gtagagtatc aagtggcgca
     4921 gcggatcgtt caacgtattg aggtaatcgc aggtgtatcg tttcccgaag aagaaattgc
     4981 ttatttgaca ttacatctca tggctaagtc gaatcacaaa gaaaatcaaa atgatcagga
     5041 actatcaaag gaattagcga aagttctgaa aagattgtct caggaatttc atttttcatt
     5101 agtagaggat ctccagcttt tcaatggact actcgatcat ttgtcaccga tgatgattcg
     5161 attgagccga ggtattcgca ttgagaaccc attgactgag gagataaaga aagaaaatcc
     5221 caaagtcttt gacgcagtaa aaaggcattt cagcaacatg ccggctttga aaaactatac
     5281 catcaatgaa gatgaatggg cctatttggc tttgcatctc atggcggcat tggaaaaaga
     5341 aagagctgcg cataaactac atgcattgat tatctgtgca acgggttacg gcagtgccca
     5401 actattaaag aatcgcgtag tcagtgaatt cggtaaaaat attacagtgg taagtgtaaa
     5461 aggctattat gagatcaatg aaacaacttt aaaaggaatc gacctgatta tttcttctat
     5521 tgatctttcg acaatgtttt tcaaaattcc agttttacat gtcagtattt ttttgaatga
     5581 agatgatgtt cgtaaaatac gaaaggtagt tggagaatct ataccctatc attcctcaga
     5641 tagaccgata ccagcatttt ctctacagca aaaaaagcag atttacaccg aacagttgtc
     5701 tgaaaaattt ttcaagactt atacgtacga accgaaaaag gaagaaattc ttcatgattt
     5761 gctgcaaaag ctgagcataa atgaagaaga aggatatata agagaaatgc gaaagcagat
     5821 ccagcaacgt gaaaatatgg gacaaatcat attcagtgat acagtggcag tcccacatcc
     5881 cgctgttcca gttggaatcg aaacaaaggt agccgttgca ttgattcctt ctgggatgca
     5941 gtgggatcaa tatcaagaaa ttcattttgt ttttttagtt tcgccttctt atgtcgaaaa
     6001 tgaaggaatt acggtcgtga ctaaagcaat cgttaggtta gttgaccagc taaaagtaca
     6061 gcaggaaatc ttagctgaac ctatttttga gaatttcagc agtaaattta tcaaactgat
     6121 cgaataagga ggaaaacaga tggctgaaaa aataaacagt gaaacactac aagtgacttc
     6181 ttttgatatc attttccata gcggaaatgc acggacactg atacatgaag catttcgctc
     6241 gatgcgtaaa gagatgtttg aagaagtaga agagaagttg cgacaagcaa atgaagagat
     6301 tcttcatgcg catcagtcac aaactcaact tctgaaagaa tatgccagcg ggacaaaaat
     6361 agaaatggaa attatcatgg tccatgcaca agatcatctg atgacgacga tgacattatt
     6421 ggaagttgca caggaaatga attatttgta tcaaaaaaat aaatagaaag gaaggatcat
     6481 tgtgcaggat acagtaaaaa ggaaaatcga attagaaaaa aagcaactta gtttgaaaaa
     6541 catgtatttc aatcgttatc taatcgtacg ttacctgact gcctttttct ttttcatgaa
     6601 catgcaatgg atgattctgc ttctatcagc taaaagttta ggaagtagtt taccgatgat
     6661 tctgatttta gctattttgc ctgcagtagg agaacaagta aagctttatc gaaaacacca
     6721 aacgaacgtt ccatggacaa agtggtattt tttgttccag agtgtcttta atttattagt
     6781 gattccagtg ttgtttacct caggatttac attcttgtat ccttttatgg caaataacaa
     6841 tggaggacag ttatttgttt tcattcttgt tgtaagcggt atttttgcca gtgcatttat
     6901 acagtatcgt ttaaagaaaa tttcactcaa ccaagaccaa cagtatatcc gtattaaaca
     6961 atatgaaaaa gcgttatatt taggaaagga gaataactaa tgtttgattt tttgcagaaa
     7021 tacctgatgg gacctatggg gaaaattgcg caacttaaaa tcgttcgggc tgtcatggca
     7081 gcggggatgg cttctattcc tttcacgatt gtaggctcga tgtttttggt tttaaatatt
     7141 ttgccattac cgttcccatt tttagaagga ttttttaatg caactttttt caaagttagt
     7201 gacttgtaca tgatcgtcaa tacaatgacg atggggattt tatctattta ctttgccatt
     7261 gtgtttgctt atgaattaac gtcaattgaa cgagatgaac aaaaattaaa tgttaatccg
     7321 ctcacggggg cattactatc tgtttttgca ttctttatgt gtatccctga attgatcatg
     7381 actgatggta aaatcagctt gattgcttct atcaatgaga cagaaactgt agtaaatggt
     7441 attaggatgg gctcttttgt cgaacgttta ggaacttcag gaatctttac agctattatt
     7501 atgtcgatta ttgcggtcga attgtattgt atgtgtgtca agagaaattg ggtcataaaa
     7561 atgccagatg ttgttccgcc aggagtttct cgttctttca ctgctctgat cccaacattt
     7621 gtcattgcgt ttgtggtgat gatcatcaat ggattattag ttgcactagg aacggatatc
     7681 ttcaaaatga ttgctatccc atttgggttt gttacgcagt tgacgaatac atggcttggt
     7741 gtcatggtga tttatttctt gatccatgca ttgtggatcg tagggatcca tggagcgaat
     7801 atcatcactt ctttcttgac cccgatcgta ttagctaata tggcagctaa cgcacaaggc
     7861 gcaaattatc cgttggcagg agaattcaac aattcttatg taaccgttgg tggatcaggt
     7921 gcgactttag gattgatcat ctttattgca ttcctcgcga aatctgatca gctgaaagtg
     7981 ttaggaaaag cctcacttgt accaggatta ttcaatatca atgaaccaat cattttcggg
     8041 atgccaatcg tctacaatcc ctatttagcg gttccgtttt tcttagctcc gatggcttct
     8101 gctacactcg cttattttgc cattcggctg gaaatcgtca aaccgatgct tgcacagatg
     8161 ccgtggcctt caccagtcgg gatcggagca tttgttggta gtggtggtga ttggaaagct
     8221 gctgtgttag cagtcatttg tgcaatcatc gcattcatta tctggttccc atttatcaaa
     8281 ttctatgata ataaattatt aaatgaagaa agagaaaagg cagcagaatt agctagtgaa
     8341 aagttaaaat gatttctaag aaaaaaggaa ctgtgacaaa aaatcacagt cccttttttt
     8401 cttagaaatg ggaaaccact agtatataaa taccattatt cttcaatcaa ccgcttcacg
     8461 attgcataat ccccttcata aggttcatct acaccattga ttttttgata gggatccacg
     8521 ccttttcccg caataacgac tgaatcttgc ggagcgcttt ctgctaaagc gcgtcgaatc
     8581 gcttcaggac gatccatttc ataatgaacg atcaaatctg gattagtaat tgcttcattg
     8641 atttcttccg cgattttttt cggatcttca aatgctgggt catctgccgt caaaaaggcg
     8701 atgtcagctg tttctgatag cacttttcca aaatcatgtc gacgggagat tgctttgttt
     8761 cctgggctgc ctaatacaac aattacacgg ccatctggat gttcattttt ggcaaatttc
     8821 agcaatgttt tcaagcttag ataattatgt gcatagtcca catagacatg cgctccattg
     8881 gattggatca attgatccat tcggcctggt acacgagctt cttttaatcc gtcttgtgca
     8941 tcttgactgg aggcacctgt tagtgctgcg gcaatgatcg cactggctgc attttcttgg
     9001 ttgaatcctc cagccagcaa aatatcataa gcagtatcgc agatagctaa gcgatcttca
     9061 tgagaagata aagtaaaacc gtgagtacct ttatctgaac ggatcacttg ataattgctt
     9121 tcttccgaac gaccataagt gatcgttgga atctggaata gatcggctgt ttccctaagt
     9181 aaatcaaaat agtcactttc atgatttaaa acaactgttt ttgaattcaa gatcaattgt
     9241 cgcttgcaat agaaatagtc atcaaatgtc ggatgttcga tcggactgat atggtcaggc
     9301 gagatattca agaagattcc gacatctaaa gtcaagccgt atacgcgttg tgttttgtaa
     9361 gcttgtgaag aaacttccat cactagatga gtcataccat tttcaactgc ttctgacatc
     9421 atacgatata aatctaatga ctcaggcgtt gtcaaatggg atttgaaata tgttttgcca
     9481 tctaacgttg tattcatagt agaaagcaat gctgtttttt tatttgttgt gtgatccaag
     9541 attgcttttg taaagtacgc agcagttgtt ttaccttttg ttccagtgaa tccgatcact
     9601 ttcaatttat tttgcggata gtcgtaaaaa gccatagcaa gaagcgccat tgctttacgg
     9661 atatccgtta cgatgattcc tactgctgaa ttttcgtatg gttgttctga tacataatat
     9721 tgaataccct gttcgattgc tgaatccaaa tattcttctt tgaaattcat tcctttacag
     9781 aaaaacaaag tagaagcatc agcttttctt gaatcataac ttaactgaag aaattcagct
     9841 ttttctggta catcaagatg ccagcctctt gttgaaacaa attcttttaa tagattttct
     9901 tttaatagta aatgacggat gtcttctaaa gagaagctca ttgattgatc cctcgcttta
     9961 ttcaatttct tggtttatta tagcacactc tttttaatat atcgtttgtt tccgctatga
    10021 caaaatccag ctttattcaa attttcttga cacaggggac aagcggatga gtattttcat
    10081 aaacaatgaa ctgactgtaa tagataggag aacgaatagt gtctccaaca atccaaaaac
    10141 ataataattc aaaaagacga taagactatt ggtaagtaaa agtccttgcg gcattggaag
    10201 ccgaaaaaat ttgtggaaaa taatcggcgg tatcgttata ccgccatttg aggccccgac
    10261 tgtgtacaat gtgtaaaccc caagactgaa caaaagactt cctgaaatca gtgaaaagaa
    10321 atgtgaggag atcatttcca cttttggaac aatctctaaa acaacaggaa aaagcagact
    10381 tcccgctaca gtcttaaaaa atactgattt tcctaatagg acagcggcta gaagcagcat
    10441 cataagattg atgctccaaa cagtaactga gcgttggata gaaaaggccg tttcaactaa
    10501 atgtccgatg gcgcccactc cggcggaagc tatatcgtga gggagcaaga accaattcaa
    10561 tccaactgtg ataaagaaaa gacctaaaaa tataacgggt agttttttta tttcttgtgt
    10621 cattgatatc tcctataaat gttagccata aaaggctgta tatttcttta ctttaccaaa
    10681 aaaacgaaac cgaattcaaa aaaacaattg ttcttataaa agttatataa aatcgattgc
    10741 cagtttctgt tttaccaatt aaaatgatag taatgttttg tagaaagttg gaatctgacc
    10801 gatggataat caaagaaaac cagcattaga tcaattaaca ccgcaagaaa aaatggcacg
    10861 aggctctgct tggatgaccg ccagtaatat catttcaaga ttgctaggcg ctgtctatat
    10921 cattccctgg tatgcttgga tgggcgaaaa tgctaaggct gccaatggat tattcaatat
    10981 gggatacaat atatatgcat tgtttctact gatctctaca gcaggaatac ctgctgcgat
    11041 tgcaaaacaa actgcacgct ataattcatt gaatgaatat ggcacttcac gacgattatt
    11101 tatccgtgca ttacagatga tgggcgggtt aggcctgttg tttgctttgt tcatgtacat
    11161 cgcctctcct tggctagctc atgcttctgg tggcggagaa gaactgattc caacgatgcg
    11221 ttctttgagt atcgctgtat tggtttttcc ttgtatgagt gtgatacgag ggtatttgca
    11281 aggcaatcaa gaaatgatgc cttatgcgct gtcgcagatt gtagaacagg tggcacgtat
    11341 tttttatatg ctattggcta cattcatcat catgaaagtc atggatggtg actatgtgac
    11401 ggcggtcacg caatcaactt tcgcggcatt tatcggtatg ctagcaagta ttcttgtcct
    11461 tttgtatttt ttgaagaaac atcaagcgta tacatcggcg tttattcact acagcgaaaa
    11521 caaaataaat attgcaacga aggaattgtt gttagatacc gttaaagaag cgattccgtt
    11581 tattattgtg ggttcagggg taacgatctt caaattagtc gatcagttca cttttatgaa
    11641 gatcatgtct gcatccaccg agtattccaa tgcacagtta ctggatcttt tttcgatttt
    11701 tagtgccaat ccagataagt tgacgatggt agttattgca ttggcaacat cgatcgcgtc
    11761 tactgggtta ccgttgatta cagaagctgt tacgttgaaa gatcgagtag gtctggcaaa
    11821 attgacaagc ggaaatttac agttgttttc attttttatg tttccggcga catttggtgt
    11881 tatgttactt gcctatccgc taaatacatt attttataca ccggattctc taggaagtaa
    11941 tgtactgatc caagcaagtt ttgtaggact cttcctagga ctatatatgc tagtttccaa
    12001 catgctgcaa ggaatgtttg aaaacaaggc ggcaattaat tatttggtta ttgggtttct
    12061 agtgaaactc cttcttcaat acccagccat tcgtttattt gaagtatacg gccctttatt
    12121 ggcgacaatg atcggatttg ctgtgtcttg taccttgatc ttaaagagaa tccatgaagt
    12181 agcccgcttt aaaccaagtt ttgtctggcg caggacattg ctgatcttta ttcttacctt
    12241 gattatgctt ttggcttcgt ggatcacaaa gatgattttt ggtgcttttt taaacgaaga
    12301 tagcaaattc cagtctctat tgttgattct tgtagtagca ggtatagggg ctttagtgta
    12361 tggttattta gctttgaaaa tccgcttggc agaaagacta ctaggaccag gaatagcgcg
    12421 tttacgacat aaattaaaaa taaaataagt gaatcagaag agctagattg atgctctttt
    12481 gaaatggggg aaacgcatgc gtttagataa gtttttagca gatatgggac ttggcagccg
    12541 caaagaagtc aaaggattaa tcaaaaaagg aacgatcgaa gtcaatggac aagtggtgaa
    12601 aagcgataaa gcgcaagtaa atgaattcga agatgcggtt acttatttag gagaaatcat
    12661 tacgtatcaa aaagattttt actacatttt gcataaacct gcaggagtca tttctgctac
    12721 tcaggataat catgatcaaa ccgtaatcga tttattggaa gaccaggatt atcgggaaga
    12781 tctttttcca gtcggccgat tagataaaga cacagagggc ctcttgattt taacgaatga
    12841 cggggtgttt gcccatcagt tactatcacc taaaaaacat gtggagaaag aatatctagc
    12901 tgaggttagc ggtataatga cagaagaaga tatccgttta tttgcagaag gactgattat
    12961 tgatggcgat gagcagacat tgccggcaaa actccaaatt gatcaagtag atcaagagac
    13021 agaaacttca attatccgtc tgattttgca tgaaggaaag tttcaccaag ttaagcgaat
    13081 ggtcaaagca gtaggaaaag aagtcttata tttaaaaaga atccgtatgg gaaaattttg
    13141 gctgcctaaa gatttgaata aagggcaata tcgacccatg accaaagaag agctagaaca
    13201 agtgagagaa aaataattga atggatagct aaaagaataa gcagagtagt tgtagcgcca
    13261 tctgaaaagc agacttgtcc gtctgacttt cggatggctt ttttgtgaaa tttcggctta
    13321 tttccgtaga agctacttct ggaacaccgt ttgttcggaa taagggactg tgacaagact
    13381 tttgttacag tccccattgt tccttgtgac tcagagttag atagtaagga cacgatctcc
    13441 ctaatactca ggccaaaacg ctgaattcac aacctctgat aaacggtgtt caatcagctg
    13501 accctcggta ttagctcaaa aaacggcaaa atatgaggaa ctattttccc gtttttttct
    13561 ctaatactca ggccaaaacg ctgatttcac aacctctcct atactttgtt tcattttccc
    13621 tatactttgt ttatttattc tcattattga aagcgctata attacgttgc gaatgaatcg
    13681 aaaggggttt ttagatgaaa aaacgaaagg ggttcaatca tttttttatg aatctatggc
    13741 gttataaagc acttgtcctg atggctgtac cgggtatgct ttggatgatt tttttctttt
    13801 acatacctgt aatggcgaat gtcgtagcat tcaaaaattt tcatatttca gcagatgggt
    13861 tcttggctag cttgagggaa agtccttggg tgggttggga aaatttcaaa tttttatttt
    13921 cttcggatca agcatttctc atcactaaaa atacaatttt atataatgta gcatttatcc
    13981 ttttgaatct gctgatctca gtcgtatttg caatcattat gagcgagttg agaaataaac
    14041 gactcgttaa agtttatcaa acgatgtcct tactacctta ttttctatct tgggtcatta
    14101 tcagttactt tgtttacgct tttttaagtc ctgacaaagg aatattcaat cagtggatca
    14161 ctggacatgg aggagaagct gtcaattggt ataatgaacc gaaatattgg ccgtttatct
    14221 tggtgttcat tggtacatgg aaagggattg gttataacag cattatttac tttgcatctg
    14281 ttatgggaat cgatccgact tattatgaag ctgctatggt tgatggagct agcaaatggc
    14341 agcagatcaa acatgtgacg ataccacaac ttattccact aatgacgatt ttaacgattt
    14401 tagccgtagg aaacattttc cgagctgatt ttggcctgtt ttataacatt cctaggaatt
    14461 ccggtgcatt atatgatgtg actcaagttt tggatacgta tatctacaat ggcctgacat
    14521 ccacaggaga ttttggtatg acggctgctg caggacttta ccaatcagtt gtcggctttg
    14581 tcttgttgat gatcacaaat acgatcgccc gacgttttga tagcgattct gcattattct
    14641 aaggaggaaa aaaatgaaaa aaaagaaagt ggagagagtc caagtccgct ctttcaataa
    14701 gacggctaat tttttctcta atataatgat tgcactcttt gctatttcct gtattttgcc
    14761 atttatattt gttatcgcca tctcttttac cgatgagtcc atattgtcga ctcacgggta
    14821 cagtttttgg ccagaaaagt tcagtatatt tggttatacg tacttgttcg accagatgca
    14881 ggataaaatt ttccaagcgc ttttcgtcac tgtacttgtt actgttttag gtacactgat
    14941 caatagcacg gctacttctt tatatgctta tgcgatttca cggtcaaact ttccattccg
    15001 tcgttttttt accgtttttt gtttgattac gatgttgttc tcaccaggga tggtggccaa
    15061 ttatcttgtt atgacaaatc ttcttcagtt aaaagatacg atttgggcat tgatcttgcc
    15121 aatggctgtc agtcccttca atattattgt gatgcgcaca ttctttaaac gttcggtctc
    15181 tgattcgatt attgaatcgg cacggatcga tggagctagc gaactgcgaa tatttgttca
    15241 gatcgtttta ccgttagctg ttccaggtat tgcgacaatc agtttatttg ccgcattggg
    15301 ttactggaat gactggttca atgctttact atacatccaa gatgataagc tagttccact
    15361 acagtatctt ttgatgaaaa tccaaagtaa tattcaatat ctgacacaaa attcaggagc
    15421 aggaagccaa ttgacaggcg gattagcctc agttccagga gaatctgcca gaatggcgat
    15481 cgtagtcatc tcgacgttgc ctattgcgat cagctatcca tttttccaga agcattttgt
    15541 caaaggtcta acaatcggcg gagtaaaaga ataaagaaac aaaaatataa atcataaaat
    15601 taggaggaag aaaaatgaag ttatggaaga aactagcctt tacaggtgtt tcagcgttgt
    15661 tgttgggaac attagcagca tgcggaggtt ctggttctaa agaccaggca gaagctagca
    15721 attcggacac tttgcagatg tatcaaatcg gagataaacc agataatttc gatcaattga
    15781 tggaagtagc aaacaaacga atcgaaaaag agatcggtgt aaaagtcaat atcaattaca
    15841 ttggctgggg cgattacgaa aagaaaatga acgtcatcat ttcttccggg gaaaattatg
    15901 atatcgcctt tgcgaacaac tatgtttcca atgcccaaaa aggagccttt gctgatttga
    15961 ctgaattagc gcctaagtac gctgaaaaag cttataatga tttagatgaa gcatatatta
    16021 aaggaaatct ggtcaatgga aaattatatg ctttcccagt caatggaaat gtctttgctc
    16081 aacaagtact tacttttaac aaagctttac tagataaata cgatctttca attgatggaa
    16141 tccaatctta cgctgatgca gaaaaagtct tgaaggaatt ccatgaaaaa gaaccaaaca
    16201 cggcagcttt tgccattgga caaggcttca aagtccaagg gaactttgat tatcctttag
    16261 ggaatacgtt accatttgct attgatctgg atggagatga ttcgaaaatc atcaaccaat
    16321 acgataatga aacgtatatc ggactgttac gtacaatgca tagctggtac aaacaaggac
    16381 tcattccaag tgacgctgca acgagcaata aggattatcc actagaagga aatacttggc
    16441 taatgcgtgg agaaacacaa ggaccgtatg attatggcga tacaattttg acaaatgcag
    16501 caaaacaaga acttgtctca aaagcaatta ctgttccact aaaatctaca gctcaagcac
    16561 aaatggcaaa ttttgtcgta tcaaatactt caaaaaataa agaaaaatca gtagaacttc
    16621 tagggctgct taacagtgat ccagaattat tgaatgggct tgtttggggg atcgagggag
    16681 aagcatggga aaaagtcgat ggttcagatg ataaaatcaa attgctagat ggttatcagc
    16741 caaatacaca tatgtctgct tggaatacag gaaacaacaa gattctatat acacaagagt
    16801 ctattacgga tgacatgatt gccaaacgtg atcaatcgat tgctgatgca gaaacttcac
    16861 cgattttagg attcagcttc aacactgaca gtgtcaaaac agaattaagt aatatttcta
    16921 atgtcatgaa tcaatattta gatggattga atacagggac tgttgatcca gatgaaacat
    16981 taccgaaatt gaaagacgct ttggacaagg ctggctatga taaggtattg aaagaaatgc
    17041 aaaaacaata tgatgagttc cgacaagaat aataatgaat aaagacaaag gggttgtgac
    17101 aaaagacgtg tcacaacctc ttgttccgaa taaacggtgt tcaaaagcca gtttctcggt
    17161 attaagctaa atatatgtaa aaatgtggaa agccatattc acaaaatttt tcttactact
    17221 cgaaactaag cggctatttc acaaactctt ggtaaacggt gttcaatcag ctaaccctcg
    17281 gtattcgctc acaaaacgac aaaatatgag gaactatttt tccgtttgtt tctctaataa
    17341 tcaggtcaag gtgctgattg cccaaccttt ttttgtataa tgagaaagta taaacttaat
    17401 gtttggagga gaagatatgt tagggaaggt tttggaagag ttatttatcc ggatctgggt
    17461 cattataaaa ctaaccttgt atttctggat atatacattt gccggcggga tcatctttgg
    17521 attaggtgcg gcatggaaaa cagtcaatga actattttat ttgtacggat tcgagtataa
    17581 agaaatcaca ataaaaagag gctggaatat atataaaaga aattttttaa gaggcaatct
    17641 gctatttagt ttatttttat ctggtactgc tttattgagt tacaatttat atttatctgt
    17701 tcaaatcaaa gggctcattt ttttagctat tgattttatt ttactttttg ccttgctctg
    17761 cctatttgct acttatcaat acagtatgat tttagatagt gaatatacga tctctgttcc
    17821 taatctgcta aagctaagtt ttatttcggt tttttccagc ttttcgtctt ttctaaaaat
    17881 aattattggt agcggtataa ttttaggcgt gacttggcaa ttcaaaggat tgatcctgtt
    17941 tggtgtcatt ggtcttttga cggtttggaa tggtacgatg acaacacatt ggcgtgaaga
    18001 attagataaa cagttggaaa gttatgaata agtttcggat tctattttca aaaggaacct
    18061 tactaaatcg tctgttgcgg aaatacgcgg ttatcatgat cggtgtaacg atgactgcta
    18121 ccgttatttt tagtatccat acttgggaac aaaatcaaaa acaggcagaa aacatgacaa
    18181 gtgatgccgt tcaaagcaca agcagaatgc tgaatgataa aacaaccttg agtaggatca
    18241 tcaaaaacca gcttgtaggg aattccgaaa agatcgaaaa tgtgacgacc tacttaacaa
    18301 aacccataga tcagtatctg atgtatgtat acgaacagca aaacagtacc gatgaattag
    18361 tttctttccc aaatcaaatc aaagatctct acgcaaatta tgaagaacta agtgcgatat
    18421 atatcgtgtt gaatcaacta ccggagtatt atgaatcttc tagagaaaac aaaggtgggg
    18481 aaataaaaaa ggggacacca aaattactag acgcctttta tatcaagttg cctatcacac
    18541 aaggaggagc tgagtcagga agtattttta ttggttttca aaagaaagaa ctagatatga
    18601 ttttagaaaa tctaacgtca ttcaatggac tctctttata catgatttct ggaacgacaa
    18661 atcgactata cacattccat gataataaaa tagctaaaga aacgtttgaa agacaagaaa
    18721 tgatcatcac agagagtctg aagaaaaatt cacaattgcc gattgacgat ctggaaaaaa
    18781 acaattttgt tcaacaccaa gaactgtctg atgattatcg tatattagct gtactagata
    18841 aaaaaagtgt aaaaatcgaa acgggaaaaa atcttgcccc gctgatcatt ggtatcatta
    18901 ttttagacaa tatactgctt atctttcttt ataaaacatt caaacgatat tcacagcaag
    18961 tatctatcgt catgcaggcc atggatcaaa cagcagcagg gaatttagag acgcggatcg
    19021 acataacaaa cacggaatat gaactgaagg aactttcaat cggtatcaac gaaatgttgg
    19081 atagcatcaa tcagtttgta gaagacatct acaaattaga aatcaaacag caagacgcac
    19141 atatgcgggc gcttcaagca cagatcaatc cacacttttt atataataca ttagaatata
    19201 tccgaatgta tgcaatcagc gaaggaagtg aagaattagc agatgttgtg tatgcgtttt
    19261 ccgctttgct tcgaaacaat acgaatcaag agaaaacgat cactttaaaa gaagaactgg
    19321 acttttgcga aaaatatgtc tatttgtatc aaatgcgtta tcctaatcga gtagcctatc
    19381 attttatgat cgatcctgat ttggaaaaga tcgaagtacc taaatttgtg atccagccat
    19441 tagttgaaaa ttattttaaa cacggtattg attttactcg attcgataat gcgctaagtg
    19501 tcaaagtctt gcaggaaggc aaacgggtaa ggatcatcat caaagataat ggaaaaggga
    19561 tgactgaaaa acggctaaaa cagattgaag aaaaactgtc tcatcctaaa gtggaacttc
    19621 acggttctat cggtctgcaa aacgtgaatg aacgtttacg tgccagcttc ggcagcagtt
    19681 attatatgtc gcttgagaat aatgagacag gtggactgac cgtttctatt acattcaagg
    19741 agggatgagc gtgtatcaag tgttattggt agatgatgaa tacatgattt tgaatgggtt
    19801 aaaaaagata attgattggc aaagtttagg ctttcaaata gtagcaacag cagagaatgc
    19861 caaagaagga ctagctgtac ttgaacagcg acagattgat ttagtagtaa cggatgtgac
    19921 aatgccagaa ataaatggac tggaatttat tgaagcggct caaaaagaac gtcataattt
    19981 tgaatttatg attttatcag gataccaaga attcgattat ttgaaaggag gtatgcaatt
    20041 aggcgccgtg aattatttga tgaaacccgt gaataagttc gaattggttg aaagcctcaa
    20101 gaaaatcaaa acacggttag atcagcaaaa tgaacaaaaa aatcaacaag aaatctatca
    20161 agaactgtta ttcagtcaat ggttgaatga agaattggat gaaataagtg aagaagaaat
    20221 aataggacaa ataagtgaga agcagcatag gatagtattg attcaactgg caagaactca
    20281 tgatactctt atcaatagat ggttgcaaga acggcaacaa atcttttact atcaacgaaa
    20341 ttacggagac cgtgtattga tcacgttgtt gttggaggca gatgaagttg atggcttctg
    20401 ttgttttgtt caagaaaact ttcctgatca ggaatggctg atcagtatcg gggaagagac
    20461 agattctttg gacaaaatcc ctgaaacatt ccaacaagcg aaagacaatc tacagttgca
    20521 tcaattttat ggagataaag acgagcatgt tttttacgca gtacaagcag aaacaaaaga
    20581 tcaaaccatc gatttttcaa gtttcagacg cgtgctgcaa aataaacaat tagaagtcgc
    20641 tcaaaaaatg atcactgatt tttttgaaca gtttcagtta gcagccatga tgccggaaga
    20701 tatacgatat tccagttttt tactgtttat ggagattcaa cgggaattga ttgatctgga
    20761 agatgaggaa tatttacaag gaatcgaaaa aatccatcag gcaaaaacgg tgcaagaact
    20821 tcagcagcta cttctgtcat tcatcaaaaa gcatcagaga cagaaaaagt acagtgacaa
    20881 tgtggaaaaa gtaatcgtaa tcctgcacca gcattatcaa gaaccactta cactcaaaga
    20941 agtgtcagaa aacctgcatt taaatgtcat gtatctagga cagctgttca aaaaagaaac
    21001 gaaaaaaagt ttttcagctt atttgaacca tttacgtatg gaaaaagcga aacaactgct
    21061 tttgcacagt aatcaaaaca tcaatgagat agcaagtgag attggctaca acaacaccac
    21121 gtatttctct aaattattca agaaaatcgt cggcagatcc cctaaagagt accgagaaaa
    21181 cagtggagaa tcataaaaga aaaagccaat gtaatgaaat aacttataaa aaattgtcta
    21241 gaaatctaat tttgggctgt tcttattact tgaggcaagg cagctttttc atgacctctc
    21301 gataaacgga gttcaaaagc cagtttctcg gtattaagcc aaatttatgc aaaaatgtgg
    21361 aaagccattt tcacaaaatt tttcttaata ctcgaaacta aacagctttt tcacgacctc
    21421 tccactaaac ggtgttcaat cagctgaccc tcggtattag ctcaaaaaat ggcaaaatat
    21481 gaggaactat tttgccattt gtctctctaa tactcaggtc agaacgctga tttcacaacc
    21541 tctcaataaa cggtgttcaa aagcttgcat ctgcggtaat aagaccaacc aaacgaaaaa
    21601 tatgaggatc tatttttgct tggctgttct tattacttga tgcaggacag ctttttcaca
    21661 acctcttgtt aattatagtt tgataaggaa aaaggcaaat cttttgcttg atatttctta
    21721 gggtgaggga tgatccctaa ttggtaagag atcgtgccgc ctttcagcaa atcttgatgg
    21781 gtaaaatata atttcgtata ttctttgtcc atccgtttga ttttatggat aaattgttgc
    21841 tgcggccgat taggcgttgc ttcaatcgtc aattcctttc catttgacaa aagcaaaaca
    21901 gccttgtcaa ttaatggcat accgataaca tattcaccgg ttccaggcgt gacaggataa
    21961 aatcccagac tattgaagat ataccaagcg gccatacttc cattgtcctc atctccaggg
    22021 taacccattg gagaatcgtc gaaggtctga gtcatcaact gtttaagcag tggctgtgcc
    22081 atttcaggtt gtcctatata actgaacaag taaggatagt gaaaacttgg ctggtttgaa
    22141 atagctaatt gtccaaattc tatcgcggcc atctcactca tttcgtggat ctcaaaacca
    22201 tatcctcctg ggtcaaacgt tgggggctga ttgcacagct caatgagttt ttctttatat
    22261 ctctcactgc caccatattt tccgatcagt cctgaaaaat cgtgataaac agcaaagctg
    22321 ctttgccaag cacttccttc tgcataatct tgtccccaac gattagctga aaatggttct
    22381 ctgaacttgc catctttatc ttttgaacgc ataaatcctg actcatagtc aaagatattt
    22441 tgatagttca atgattgctg ctgatatttc ttcgtcattt cctcttcttc tagtaccttg
    22501 gcaacttggc taatacaaaa atcgctataa gcatagtcta atgtgtgatt gactgattcg
    22561 tggtagtgat taggaacata gccatatgtc aagtaatctt ctgttccttg gcgtccataa
    22621 tttggatgtt tgctttgaac cgtagcacct ttttccattg ccgttagaaa ttcaggcatc
    22681 aagtctcgtc ggatatcttt tacagcagca tctgcaatga ccgcatcgat caatgtccca
    22741 ggcataagtc cacgttcatc aggagacagc cattttggca aatagccact ttctctatag
    22801 ctgttcaaaa aaccttccag catttcttcg tatttttcta cagcaatcaa agaataaaga
    22861 ggataaaccg ttttatacgt atcccaaaac ccattatttg tatagagaac accaggtttt
    22921 atagatcgac tagtcgtatc atagtggatt ttttgcccac taggatcaat ttcataaaat
    22981 gtttgtggaa ataaaaacac ccgatataaa ttatgataaa acgtccgcaa ttgttgttga
    23041 tcatggtgtg tgagctgtat acgatcaaaa taggactgcc attgttcttg actgtgagca
    23101 aggtaagtct ctttgctttg gttttgttct agttccaggt tataagctgc ttgttccgag
    23161 ctgataaaag atgtcccaaa tcggatagtt tgtttttttg tctgttcaaa atacaacggg
    23221 atcgagtcgc tatttttgtt ggaaacagct aactcatcaa ttgttaaagg atattcaaat
    23281 ctcaatataa aataaaaaga aaaatcagga tcttctgaac cagcaaaatg tgtgattttt
    23341 ccttccactg tgtaaggatc tataacaaag agctgatggc gtcccggaaa ggataaaagt
    23401 aaaccgctgt catttttgct gtaatcaata gataagattc cgccatacat gctaggtatc
    23461 aatgtagaac agatgccata acgtaattga cagatcgaca gatgagtcgg gcaaaatata
    23521 ctttcttctg ggcggtaaga actttgagca tggaaaaggg tgttctcctg tagttttcca
    23581 ttgatcggcg taaacagcat atgactgaaa tcacccatcc aaggacttgg ttgatgggta
    23641 agacggtagc cttgaaaaac gcggtcatca ggatgaaacc accagctgcc gttttgatcc
    23701 gtagtttgcg gtgcaaaata attcatccca aaaggaacgc cagtataagg ctggcagttc
    23761 ccattagaga aatttggctg attcgctgtt gcatgtctag tatctatttg accgatattc
    23821 attttatttc tcctttgttg attgtctttt gatgaatgaa actggaaatt tactatcgga
    23881 tggtcgatct tttgtctcta accaagtgac caaagcatct cccgcaagct tacctaactg
    23941 ttcaaaatct tgtgcgatgg ttgtcagtgg cgggtcaaca agagctgctg cttggatatc
    24001 atcaaatccg ataattgaaa aatcttcagg gatatgataa ccatgctgtc tcaagagatt
    24061 catggtctgg atagcgacaa catcgttttc acaaacaaaa gcagttactt catacttagt
    24121 gatataagaa agcaattcat ctaatgtcgc gcttttgtca tccagtgaag tgtggaaagt
    24181 caaaccagct ttgtccaatg cttcaaggta accaaggtaa cgctgtcgaa cggattgtgg
    24241 atgagtctgc gtaccaaaca aataagcgat ttttgaatgt ccctgttcga tcaaataaga
    24301 ggcagcaagc gcaccgcctt ggaaattatc ggaaagaacg gtaggaaaag gtaactcata
    24361 gattttttta tctaatatga cgacagggaa ttctttcaat gaaagctcaa aaagtaagtc
    24421 aagatgttgt tctgtatcaa gagcataata aatcaatccg tcaaattcat tgattagctc
    24481 ttttgctgtt ttattttgta gaaagtcaag cgtcgtcatc atgacatcaa tctgtttatc
    24541 ttgcatcaca gggttcaatc ccttgctaaa atcaccaaca gacaaatcag cgacatatgg
    24601 aagaagaaac agaatccgtc gtgtttttgt aggagaagca agaatctgtt ccggagaagc
    24661 ggatttaacg aaactgcctt tcccgcgaac gcgataaata agtcctaatt gctctaattc
    24721 agtcaatgca cgtttggaag tgattctgct tactttatag gtacgtgaaa gttctttttc
    24781 agttggtagt tggctgtcta caggtaattc accagttaaa atagccgttt gcaaatcatt
    24841 aaatattgtc tggtacaatg gttgattcat ataaacacct cttaatgata tatcatattc
    24901 aaataatacc ataatggatg aaaaagtaaa taaaaagata ttttttgaaa gcgtagacat
    24961 aattggctgt atgaagtata atctttaaag atatatcaaa tagaaagaag gttttattag
    25021 tggcttataa agatatacca aaatcggtgc agaaatttat ggaagatatc acacaaaaat
    25081 gtggggatat ccatgcggac tgggcaaaga attttacagc agcatttgcc aatactctgt
    25141 tgacaacagt caaaaagcaa aatgacggaa ccaccttttt attgacggga gacattccag
    25201 cgatgtggtt aagagactct actgcacaag ttcgtcctta tttagtgatt gcaaaagaag
    25261 atgaggaatt agctgacatg atcagcgggt tagtcaaaaa gcaatttttt tatatcaata
    25321 tcgatccata tgcgaatgcc ttcaacgaag aagctaacgg tgctggccac caaacagatc
    25381 atacaaaaat gaacgattgg atctgggaaa gaaaatatga aattgattct ttatgctacc
    25441 caatacagtt ggcctatctt ctttacaaaa atacaggaaa aactgatcaa ttcaatcaat
    25501 cttttattga aggtatcaaa aaaatcttgg acgtgttcaa aacagagcaa gatcatgaac
    25561 actctcctta tacatttgta cgagacacga caagaaaaga agatacgctg atcaatgacg
    25621 ggcgaggtgc aaaaacagct tttacaggaa tgacatggtc tggtttccgt cctagcgatg
    25681 atacttgccg ttatggatat ctggtaccat ccaatatgtt tgcggtggtc gtgttaggtt
    25741 atgtggaaga aatttttcaa acgatactcg atgataaaga aattgtacag caaacacaga
    25801 aattgaagaa agagatccaa gaggggattc agaatcacgg acgaacggtt aatcaaaaag
    25861 ggcaaacgat ttatgcatat gaagtagatg gaatgggaaa cgccacagtc atggatgaca
    25921 gtaatgtgcc caatctgatc gccgcacctt acttgggata ttgttctgaa caagaggaag
    25981 attatctgca aacaagaaga acattgttga gtaaagaaaa tccatatttc tatgaaggaa
    26041 agtacgcaaa aggaattgga tcctcccata cgccagaaaa atacgtttgg ccgattgcat
    26101 tagctatgga aggaatgaca acgtcagaca aatctgaaaa agagcggata ttgaatttac
    26161 ttgtagcaac tgacgcagga acacacctta tgcacgaagg attcgatgtg aacaatcctg
    26221 aaaattatac gagagaatgg ttttcttggg caaatatgat gttttgcgaa ttagtcatgg
    26281 attactttga tattagagta gaaaagtagg aggtatcgta aatgaaaaag aaagtatata
    26341 tcatttctca tagccactgg gatcgtgaat ggtacatggc ttacgaacag catcacatgc
    26401 gactgattga attgatagac gatctactag agctatttga agttgatccg tccttcaaca
    26461 gttttcattt ggatgggcaa acgattattt tagatgacta tcttcaagta aggccagaaa
    26521 aaagacaggc aatccaacaa gcaatcaatg aaggaaaatt gagaattgga ccattttata
    26581 tcttgcaaga tgattttctt atcagctcgg aatcgaacgt gagaaatatg ctgattggca
    26641 tggaagaaag ccgtaaatgg ggaacccctg tcatgttagg ctattttccc gatacatttg
    26701 gaaatatggg acagacgcct caattaatga aacaagctgg tatttcagca gcagcgtttg
    26761 gccgtggtgt aaaaccaatt ggctttgata atcaagtttt ggaagcagaa aactattctt
    26821 cccaatactc agagatgtgg tggaaaggac ctgatcaaac agcaatcttt ggtctgctat
    26881 ttgccaattg gtatagcaac gggaatgaga ttccagtaga aaaagaagca gctcttgcct
    26941 tttggaagca aaaattagcg gatgcagaac aatatgcctc tacgaaccac ttattgatga
    27001 tgaatggtgt tgatcatcaa ccggtacaaa aagatatatc aaaagcaatc catctcgcaa
    27061 atgaactgtt tccagattac gagtttattc attctaattt tactgactat ctggaagcag
    27121 ttcaaaaaga tgtgccagaa gacttaggct cagtagaagg agaattgaca agtcaagaaa
    27181 cggatggctg gtatacttta gccaatacag catctgctcg ggtttactta aaacaatgga
    27241 ataccaaggt ccagcgacag ctagaaaata ttacagaacc acttgcgacg atggcttatg
    27301 aagttagtgg aaactatccc catgatcaat tagattatgc ttggaagaca ttaatgcaaa
    27361 atcatcctca cgacagtatt tgcggttgtt cagtcgattc tgtccatcgg gaaatgatac
    27421 ctcgttttga aaaagcagat gaagttggaa agtatcttgc acaagattcc ttagaacagc
    27481 tgaccgcagc aatcgatacg accggattcc caaaagacag ctttccattt gtcattgtaa
    27541 atactgcagg aatggataaa actggtgaag cagaaataac catcgaatta gaaagaaaaa
    27601 gattcgctga aggaatacct gaacaactat atcaagagtt agaaaatttg cctaaacgta
    27661 agtatcatgt agaaacaaaa agtggggcca ctataccagc tattttatct gaagaaactg
    27721 tccaatttgg ttatgatttg ccgaaagacc gtttccgtgt gccatatatg gcaagaatga
    27781 tcaaagtgac tttaccatta gaaaacatgc cagcattttc ttgggaaaca ttcgcgcttg
    27841 tagaagggga agcgaaagca gaagaaaagg aaacaatgat tcatcagagt ggacgaatca
    27901 tcgaaaacgg ccctctacat ttgacgattg aaaaaaatgg taccattaca atggaagatc
    27961 gcaaaaacaa acgaaagttg aataatctgc atatttttga agatatcggc gatataggaa
    28021 atgagtatat ctttaaacaa cctttctgtg atcagccaat cctatccagt aacaaagaaa
    28081 actctgaagt aaaagtatta gtagatacac cggaaatagc aaaaataagt attctacagg
    28141 aaatggaaat ccctgtttct gcagacgagc gtttagaaaa agaacagcag atggttgtgg
    28201 aatttcgtta tcgaaaagca gaacgatcca aagaaaaacg aatccttcaa ataaaaacaa
    28261 tcatgacaat cagaaaagat agtaaaaaaa tcgactttga aacgactctc gacaatcaga
    28321 tgaaagatca tcgcttacgt gtcttgtttc ctacaaagtt acatgtggaa catcacgaag
    28381 cagatagtat ttttgaagtg gtgaagcgcc caaaccatgt gtctaaaagt tgggaaaacc
    28441 ccacgaatcc gcaacatcag caagcatttg tcaatattca tgatgaagag tacggtgtaa
    28501 cagtcggaaa ctttggtttg aatgaatatg aagtaacaga agacggacaa atcgcagtga
    28561 cgctacttcg cagtgtggga gaactaggcg attggggata ttttccaaca ccagaagcac
    28621 agtgtctagg tgagcatcgg ttcaattaca gcattgaact acatggacca gaagaaaaat
    28681 tctctactta tttgcatgca tacgcagcac agattccttt ttccactcaa caaatcaaac
    28741 atcatgaagg aacattgatt tcaaaacaac aatatttaac gataaaaagt gaaacgtttg
    28801 caattacagc tttgaaacgc agcaagttta gtgataaagt agtagtaaga ggtttcaata
    28861 tgtctagtca tttagaaaaa ttggaaataa ctaaagacaa tggaaaaact gtcatattga
    28921 atctgcttga agaaccaacg aagcaagcgg ttgtcccaat aatccaacct tatgagattc
    28981 ggacaatcgg attcgaggag gaaaacgaat gtatggcgga atagaagcag gcggaacaaa
    29041 atttgtgtgt gcggtttcag atggtggaga aattttaga
//
LOCUS       DADLIO010000029        28727 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.029, whole genome shotgun sequence.
ACCESSION   DADLIO010000029 DADLIO010000000
VERSION     DADLIO010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28727)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28727)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28727
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.029"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(70..1155)
                     /locus_tag="JOX41_001441"
     CDS             complement(70..1155)
                     /locus_tag="JOX41_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAY6449193.1"
                     /translation="MKKICFISGVISRSGGTERVGSIIANSLSDLGYDVTILSFWNSG
                     EPYFGLDKTIKVDYMLNPKTEGKLYRTYLYPVWKLHKYICKNEFDIVIDIDTLLSLYT
                     TRAIKGTKCKLISWEHFNYWTMEMLKEKKRFKAKKLIKKYAKRLVVLTEEDRQKHIDE
                     YSLSEDFVITMPNPCISNIEYEYHYDKKRFLAVGRLVEEKNFADMISAWKIVEKKVDD
                     WDLIIVGKGELEKDLRQQIKDLNLQRVTIAGHSDHVEEYYKSASCYVLSSVYEGFPMV
                     ILEAQSYGLPVISYDCKTGPRDLVHHNFNGMLVEDKNIDQLAKSMIMFTKNTDLAMRM
                     SLNAYNNVQKFNLKEITKQWVALIENV"
     gene            complement(1170..1889)
                     /locus_tag="JOX41_001442"
     CDS             complement(1170..1889)
                     /locus_tag="JOX41_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HAY6449194.1"
                     /translation="MIPKKIHYCWFGGNPLPKKDRKCIESWKKYCPDYEIIEWNESNY
                     DLNKNRYMADAYKERKWGFVPDYARFDIIYNHGGFYLDTDVELIKSLDILRENHAYMG
                     FEGEIWVNGGIGFGAEEGHSVIKGLRDIYDSLSFYQNDGTLNLKPSPYYITDYLESIG
                     LVRDNSEQIINGLHIYPTDYFAAKDYDTGKIYKTSNTISIHQYNASWKTPKQKFVYRL
                     KSTIGQKKFNRLLALKKFLHL"
     gene            complement(1886..3196)
                     /locus_tag="JOX41_001443"
     CDS             complement(1886..3196)
                     /locus_tag="JOX41_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HAY6449195.1"
                     /translation="MRISIKRWSGADWTLFTLAFFAISIVLVYTFNAPRAILYLGDII
                     NIFVLLNALSFRRRKGIYASKNEMLIVLFLLVSICSSVINLENIGLIIWGIRNNTRMF
                     IVYINCATYLTIKDYYKVFAIIEKLFWISLPLCLIERFMVTYPTGTIVGDMIGGVFWN
                     YSGCNMPLNLILCVTVTVVTIGYFKGEKNFIHFILCVCAALFMSALAELKVFIPELFI
                     IFVAIVFTLKVDFKVVIKILSCVILVSIVLSFFITIFITLNDNGQSYADNFTIQGLLE
                     YASRDSGYDGVGDLNRITGISRVVDEIFNNNFRLVLMGVGIGNAEFTNFFVSEFYKSF
                     GNLHYQYFHHIWLFIEVGILGVSIFLFFIIKTFFNAKRSFMKDKDASLVKVIAIMSVF
                     FFVYNTTLRGETTGPLIYMILAMPEVVKRKEHYYSEKNTKGEIL"
     gene            complement(3223..3813)
                     /locus_tag="JOX41_001444"
     CDS             complement(3223..3813)
                     /locus_tag="JOX41_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HAY6449196.1"
                     /translation="MEISSKEYLKAVLRMEKNLYIESKGQHTKLLKIMKSHPDYNAWR
                     YTRRMRITSYYYSKRKKNIIYAIMYIVSCRRMNSLGRKCGIECGENVFDEGVRFYHTQ
                     GIVINGNAIIGKNCYLYGNNCIGNDGIDPKCPVIGNNVRVCVGAKIIGNVKIANNVVV
                     AAGAIVIKDCLENGAILAGVPAKIIGYVNLTKVFLE"
     gene            complement(4131..5192)
                     /locus_tag="JOX41_001445"
     CDS             complement(4131..5192)
                     /locus_tag="JOX41_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAY6449197.1"
                     /translation="MNSSDLISVIIPVYNVEKYVGSCLESVCNQTYKNLDIIIVDDGS
                     KDSSNKICEDYALKDSRIRIIHKNNAGLGLARNTGLEHVKGKYVAFIDSDDFVAANYI
                     EAMLNGIKRSNADTCYAGYYEYYDDNNIISKPARYDSTIFTNNAIIEKVLLGMIGTEP
                     SYKVDFILPMSVWHALYSSEIIQQHNIKFPSERDYISEDIIFHISYLQHSKITSFIKD
                     CIYYYRCNNNNSLTHNFRDNEFDCNIELVKKIEGDLSYILENEIFVNKTRRLLLGRCR
                     TCIQKAVRYASFNKEFDLNSYLSKILMNDELIACIHSYPYKQNPIKQRIFNYFLLNQS
                     IIGVKTLAYLSGMGRNRRF"
     gene            complement(5760..6827)
                     /locus_tag="JOX41_001446"
     CDS             complement(5760..6827)
                     /locus_tag="JOX41_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAY6449198.1"
                     /translation="MQRVLMIGNDSSVKGGITSIITQMLNFNWEKKNIEMTFIPSYKG
                     GNAIFKSLYFMYAFAKIIGISLLSKPNIIHMHMSYRGSFSRKYVLNKWFRLLNIPVII
                     HLHGSEFKKWYDSVSVKKQNQIRLLLRESDSTIVLGEKWKKIIKEIEPNCKTVVVENS
                     IVVPEYTIKWNSKMCRFLFMGVLIKRKGVHDLVEAVKNIAEQYPEKKFIFEIAGAGDE
                     EISLKELIEEYNLQSYFEFTGWVVGEKKEECYRRSNVMILPSYNEGLPISILEAISYG
                     MPVIATDVGDISSAVRDGENGYLFQPGDVSALTSAILKINDKDKYVKFSRCSKDLAIT
                     KFNDGNFFDRILNLYQKGSKE"
     gene            complement(6847..7326)
                     /locus_tag="JOX41_001447"
     CDS             complement(6847..7326)
                     /locus_tag="JOX41_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta(1,3)galactosyltransferase EpsH"
                     /protein_id="HAY6449199.1"
                     /translation="MIFITLGSQKFQFDRLLKAIDDLIEKGVIIESTFAQSGYSDYKP
                     LNYSYKAFLNRDEFTETMQKAEMVITHGGTGAIIGAVKKGKRVIAVPRLAKYGEHVDD
                     HQLQLIRQFDEMNIIYPCYELENLEDAVKETRVRMFNKYVSNTETIINSIEVLIEKI"
     gene            complement(7343..7804)
                     /locus_tag="JOX41_001448"
     CDS             complement(7343..7804)
                     /locus_tag="JOX41_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAY6449200.1"
                     /translation="MNKKICFAASSGGHYEQLMMLKPLMEKYESFVITEQTEYSAESK
                     GEKTYYMRQVNRKEKFFLCTILINLFKSIIIYIKEKPDLVICTGVLAMIPICLITKMM
                     GKKLIYIESFAKVTSPTQTGKLMYHFADQFYVQWETMLQFYPNAIYLGGIY"
     gene            complement(7818..9068)
                     /locus_tag="JOX41_001449"
     CDS             complement(7818..9068)
                     /locus_tag="JOX41_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HAY6449201.1"
                     /translation="MKKKYNIAVAGTGYVGLSIATLLAQHHQVTAVDIIPEKIELINK
                     RKSPIQDEYIEKYLTEKELDLTATLDARSAYKSADFVVIATPTNYDSRTQHFDTSAVE
                     SVIEVVMDVNPDTIMVIKSTIPVGYTESVRETTGSKNIIFSPEFLRESKALYDNLYPS
                     RIIVGTDMTDERLLNAAHVFATLLQKSAIKENVDTLFMGFTEAEAVKLFANTYLALRV
                     SYFNELDTYAEMKGLNTQQIINGVCLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYA
                     DVPGNLIEAIVESNRTRKDFIADRVLQMAGYYNYAEYNQYDVNRENPVLIGIYRLTMK
                     SNSDNFRQSSIQGVMKRVKAKGATVVIYEPALKDGETFFGSKVINDLEQFKAMCDSII
                     ANRYDTCLDDIKEKVYTRDIFQRD"
     gene            complement(9446..10897)
                     /locus_tag="JOX41_001450"
     CDS             complement(9446..10897)
                     /locus_tag="JOX41_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAY6449202.1"
                     /translation="MYKKSSRGWVKHIDFIILDLLCIQLAFYLSYVLRQVDWNPYVIP
                     MYQNMAVFIELADLLVIFMFEAYRGVLKRGYYIEFASSVKQAIMLVLLGSLYLISVQG
                     GNDYSRVVLFLMGGLYVVITYITRLLWKHYLKHKMKNEGNKSLIIVTSSSIAEVVIRN
                     VKEHNYKMYKINGVIIIDKSMIGEDVEGVTVVSDSKNAADYLCQGWVDEVFIILNKST
                     SCMKEFIERCSEMGLTVHLNLAKVSDSALGKQSIGRIGEYTVLTTSINVMTTQQAFIK
                     RTIDILAGIVGCIATGIIFIFIAPLIYINSPGPIFFAQERIGQNGKPFKMYKFRSMYM
                     DAEERKVELMKENKMSNNLMFKMEFDPRIIGNKILPDGTKKTGIGQFIRSTSLDEFPQ
                     FFNVLTGKMSLIGFRPCLKSEYEEYDYHHRARIAIKPGITGMWQVSGRSDITDFEEVA
                     KLDTEYIKNWSMGLDFKILFKTVKTVLQRGGSM"
     gene            complement(11218..11982)
                     /locus_tag="JOX41_001451"
     CDS             complement(11218..11982)
                     /locus_tag="JOX41_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HAY6449203.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKTPVIVHPERNVHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            complement(12010..12708)
                     /locus_tag="JOX41_001452"
     CDS             complement(12010..12708)
                     /locus_tag="JOX41_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HAY6449204.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLNNAS
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILSEARQLFDV
                     VIFDMPPVVAVTDAQIMSLKTDGTLLVVRENMSRKESLTKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            complement(12720..13499)
                     /locus_tag="JOX41_001453"
     CDS             complement(12720..13499)
                     /locus_tag="JOX41_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HAY6449205.1"
                     /translation="MEETISLKEIFETLRKHLVIIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     EQIKDAISVNQAENSQMFSIQAISTNAVAAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLMTGLMLGMMVGVGLAFLLELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGTAPARPKATNDKTAPSRRSRSRV"
     gene            complement(13515..14459)
                     /locus_tag="JOX41_001454"
     CDS             complement(13515..14459)
                     /locus_tag="JOX41_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAY6449206.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDPNGDYGRQGR
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMNFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            complement(14505..15284)
                     /locus_tag="JOX41_001455"
     CDS             complement(14505..15284)
                     /locus_tag="JOX41_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449207.1"
                     /translation="MEKPFVKLLATVAVGTGAIVICLFGYHLNNQRQYHQRINYAESA
                     ITNQKDTVTSLSKEVDKLYSTKEKIFLNPEITEETVSNLSHKLSSIKLSADDYDIKES
                     ELPKEAAAIQEEKKAVLTQLEDAESKLKIQTAVNKLFTKNVSNWQQAVDDVIIKEKLA
                     SADVAHVRENMSFFKDSAWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKIRAAYATKAQTVAQQMGYSNISY"
     gene            complement(15664..17739)
                     /locus_tag="JOX41_001456"
     CDS             complement(15664..17739)
                     /locus_tag="JOX41_001456"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HAY6449208.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLAGVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLEDVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGELPQSTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISD
                     VISKDTDRFGIGLSEGQQQVIDFIKGRLRQLLTTKNIRHDVIDAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAQLEKQSEVDPELFENDAEKELHKAVEA
                     MKASFADQTIHENYDQLVALRPLIENYFDQTMVMADEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(17741..18658)
                     /gene="glyQ"
                     /locus_tag="JOX41_001457"
     CDS             complement(17741..18658)
                     /gene="glyQ"
                     /locus_tag="JOX41_001457"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HAY6449209.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPETVKEAE"
     gene            complement(19044..19862)
                     /gene="recO"
                     /locus_tag="JOX41_001458"
     CDS             complement(19044..19862)
                     /gene="recO"
                     /locus_tag="JOX41_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HAY6449210.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKEIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRHIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICERHWSMDDHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRELIDQLYDEYVGIHLKSKKFINQMKSWAHVLKTSEKDMSEKEKETPEKEE"
     gene            complement(20005..20904)
                     /locus_tag="JOX41_001459"
     CDS             complement(20005..20904)
                     /locus_tag="JOX41_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HAY6449211.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(20919..21320)
                     /locus_tag="JOX41_001460"
     CDS             complement(20919..21320)
                     /locus_tag="JOX41_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HAY6449212.1"
                     /translation="MPMDLKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFG
                     ILALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKD
                     MAAGAVLVTACFTVIVGLILFVPKIYHLLFN"
     gene            complement(21298..21774)
                     /gene="ybeY"
                     /locus_tag="JOX41_001461"
     CDS             complement(21298..21774)
                     /gene="ybeY"
                     /locus_tag="JOX41_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HAY6449213.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLELPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISTER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(21803..23995)
                     /locus_tag="JOX41_001462"
     CDS             complement(21803..23995)
                     /locus_tag="JOX41_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HAY6449214.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIVCGVTFSSVKQKAIDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNGKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSVV
                     LMKFFQLFQTEQAAYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTVILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIIYQGMSFGD
                     ATTWLTLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICRQHHGTTLMRYFYVKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKSEVEKIKEEQEE"
     gene            complement(24019..24990)
                     /locus_tag="JOX41_001463"
     CDS             complement(24019..24990)
                     /locus_tag="JOX41_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HAY6449215.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            25695..27074
                     /gene="brnQ"
                     /locus_tag="JOX41_001464"
     CDS             25695..27074
                     /gene="brnQ"
                     /locus_tag="JOX41_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAY6449216.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            27356..28696
                     /locus_tag="JOX41_001465"
     CDS             27356..28696
                     /locus_tag="JOX41_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAY6449217.1"
                     /translation="MSYSEFTKELLDILDLNLIFHEDAFRKERINDETCFVFDGTLTY
                     QPEECFHCHYQNKQTIIKWGWKKVSILLNDVSNYKTILRINKQRFKCKHCGKTFLAED
                     SVSDRRCSIARRVKQAILELLSEPLSMSLIARMKHISPTTVIRILRSLRPKTVSLNQP
                     LPEVVCFDEFKSVKNVSGAMSFVMMDGKTHQLIDIVENRQLNPLRDYFLRYPRKVREQ
                     VRLVVSDFYTPYRTLVKECFPNARIVADRFHISQHIGRAFTNHRIQVMKTFKKRDRRS
                     KHLKKYWRLLQKNAWELKGQHRYWRPSFRDHLTEAEIVDRLLSYDDSLKRGYEVYQDF
                     LSAIRRQDVPEFVALLKEDYKELPEHYQPVFTTFKKYRTEIKRALRVPYSNGPIECLN
                     NHIKVLKRIAYGFRNFQNYQERIFLYRGKYFKKTKNTTQLTKARTTTRLDKIAV"
BASE COUNT         8424 a         5960 c         4544 g         9799 t
ORIGIN      
        1 aatgtaatag gtttcttcta gctctttgat taattacgct aattttcatg tttggacaac
       61 cacaaaaaac tatacatttt caatcaaagc aacccattgt tttgtaattt ctttcaaatt
      121 aaatttttgt acattattat atgcgttcag tgacattctc attgctaaat cagtattctt
      181 agtaaacatt atcatgctct tagctaattg gtctatattc ttatcttcaa ccaacatccc
      241 attaaaatta tgatgtacca aatctctcgg accagtttta caatcataag aaataactgg
      301 taatccataa gactgtgctt ctaatataac cataggaaat ccttcataaa cagaactaag
      361 cacataacaa gatgcagatt tataatattc ctccacatgg tctgaatgcc ctgctatagt
      421 tactctttgc agatttaaat cttttatctg ctggcgaaga tctttttcta attcaccttt
      481 tcctacaatg ataagatccc aatcatctac ttttttttct acaattttcc aagcacttat
      541 catgtcagca aaatttttct cttccactaa tcgccctact gcaagaaatc tctttttatc
      601 ataatgatat tcgtactcga tattagatat acacggattt ggcatagtta taacaaaatc
      661 ttctgataaa ctatattcat caatatgttt ttgacgatct tcttctgtga gaaccacaag
      721 cctctttgca tattttttta tcaatttttt agccttgaat ctcttctttt ctttcagcat
      781 ttccattgtc cagtaattaa aatgttccca agaaatcaat ttgcactttg ttcctttaat
      841 tgcccttgta gtatacaaag acaacaaagt atcaatatca attactatat caaattcatt
      901 tttgcatata tacttgtgca atttccaaac cggatataaa taagttctat ataattttcc
      961 ctccgtttta ggatttaaca tataatcaac cttaatcgtc ttatctaacc caaaataagg
     1021 ctctccacta ttccaaaagc ttaaaatagt gacatcataa cctaaatcag acaagctatt
     1081 ggcaataata ctccctactc tttcagttcc cccagaacga gaaattacac cactaatgaa
     1141 acaaattttc ttcaaagtac ttttctcctt tataagtgta aaaatttttt cagtgcaagt
     1201 aacctgttaa attttttttg tccaattgtt gattttaatc tataaacaaa tttttgttta
     1261 ggtgttttcc aagatgcatt atattgatga atgcttattg tattactagt tttataaatt
     1321 tttccagtat cataatcctt ggcagcaaaa taatccgtag gatagatatg caggccattt
     1381 attatttgtt cgctgttatc gcgaaccaat ccaatagatt caagataatc tgtaatataa
     1441 tacggactcg gtttcaagtt caatgtacca tcattttgat aaaaacttaa tgaatcgtaa
     1501 atatccctta aacctttaat aacagaatgt ccttcttctg caccaaaacc aataccgcca
     1561 ttaacccaga tttccccttc aaatcccata taggcatgat tttcacgaag tatatctaac
     1621 gacttaatta gctcaacatc tgtatctaaa taaaatccac catgattata aataatatca
     1681 aatcttgcat aatctggaac aaaaccccat ttacgttctt tatatgcatc ggccatataa
     1741 cggttcttat ttaaatcata atttgattca ttccattcaa taatctcata atcagggcaa
     1801 tactttttcc agctttctat gcactttcta tcttttttcg gaagtggatt tcccccgaac
     1861 caacagtaat gtatcttctt aggaatcata atatctctcc ttttgtattt ttttcactat
     1921 aataatgctc tttccttttc acaacttcag gcatggctaa aatcatataa atcagtggcc
     1981 ccgttgtttc acccctaagt gttgtgttat acacaaaaaa gaataccgac ataattgcaa
     2041 taactttaac aagacttgca tctttatcct tcataaaaga tctttttgca ttgaaaaatg
     2101 tctttattat aaaaaatagg aatatcgaaa ctcctaatat tccaacttct ataaataacc
     2161 aaatatgatg aaaatactga taatgaagat taccaaacga tttataaaac tcactgacaa
     2221 aaaaattggt aaactctgca ttgccaatgc ctactcccat taggactaat ctaaaattat
     2281 tattaaatat ttcatctact actctagaga taccagttat tcgatttaaa tcaccaacac
     2341 catcatatcc agaatctctt gacgcatatt ctaaaagacc ttgaattgtg aaattatcag
     2401 catagctttg tccattatcg ttcaatgtaa taaatattgt tataaaaaag gataatacta
     2461 tcgacacaag tattacgcat gataatatct tgatcactac tttaaaatca acttttaaag
     2521 tgaatactat tgcaacaaat attataaata attcaggaat aaaaactttc aattcagcta
     2581 atgcagacat aaaaagtgct gcacaaacac ataaaataaa atggatgaaa tttttttctc
     2641 ccttgaaata tccgattgta acaacagtaa ctgtcacaca caaaattaaa ttcaatggca
     2701 tattacaacc tgaataattc caaaaaactc cacctatcat atctcctaca attgttccag
     2761 ttggataggt gaccatgaat ctttcaatta aacaaagtgg cagtgaaatc cagaataatt
     2821 tttcaattat agcgaatact ttatagtaat ctttaattgt taaatatgtt gcacaattta
     2881 tatatactat gaacatacga gtgttatttc gtatccccca gataatcaat cctatatttt
     2941 ctaaattaat aactgagcta caaatagaaa ctagtaaaaa caaaactatc agcatctcat
     3001 ttttgctagc atatattcct tttctgcgtc taaagctaag tgcatttaat aacacaaaga
     3061 tattaattat atctcccaaa tataaaattg ctcttggggc gttaaaagta tatacaagaa
     3121 ctatggagat tgcaaaaaat gccaacgtga acaatgtcca atctgctcct gaccatcttt
     3181 ttattgaaat acgcatcgtt attcaccttc tttcgctaaa aattattcta aaaatacttt
     3241 tgttaaatta acatacccta ttatttttgc cggtacacct gcaagaattg caccattctc
     3301 tagacaatct ttgataacaa tagctcctgc cgcaacaact acattgttag ctatttttac
     3361 attaccaata atctttgcac ccacgcatac acgtacatta tttccaatta caggacactt
     3421 aggatcgatt ccatcatttc caatacagtt attcccatat aagtaacaat tttttcctat
     3481 tatggcgtta ccattaataa caattccttg tgtatggtaa aatcttacac cttcatcaaa
     3541 tacattttca ccacactcta taccacattt tcttcccaaa ctattcattc ttctgcaaga
     3601 cacaatatac ataatcgcat aaatgatatt tttctttctc tttgaataat aataagatgt
     3661 aattctcatt cgacgagtat accgccaagc gttgtagtcc ggatgtgatt tcattatttt
     3721 tagtaatttt gtgtgttgtc ctttagattc tatatataga ttcttttcca tacgaagaac
     3781 cgcttttaaa tattctttac tgctaatttc cattcatatc tcctattaat tcaatttata
     3841 cttaacaatt ttattcggat ttcttgcaac aagagcatca ttcaatgcta ctgaatctac
     3901 aacgatggat atgttatctt catcgttgat tccaccggat acaatattac ttataaaaat
     3961 cgtaacattt tttccaaaag aagggatgtc cgtgatgtat aatgcccatt ttccgatatt
     4021 tccagttatt taaacctaac gaatttttac aatagtacaa gtatcacaat cattaatata
     4081 taactggaat ataaatctcc aaaaattcac tatagtacag ttttttatga ttaaaatctc
     4141 ctatttctac ccattccgct taaatatgct aatgttttaa ccccaataat ggattggttt
     4201 agtaaaaaat agttaaatat tcgttgttta attggatttt gtttatatgg gtatgagtga
     4261 atacaggcaa tcaactcatc gttcataagt atcttagaca aataggagtt taaatcaaat
     4321 tctttattaa aactagcata tctaactgcc ttttgaatac aagtacgaca gcgtcccaac
     4381 aaaagtctcc ttgttttgtt tacaaatatc tcattttcta atatatagct taaatcgcct
     4441 tcaatttttt taactaattc aatattacaa tcgaactcat tatctctaaa attatgtgtc
     4501 aatgaattat tattattaca tctataataa tagatacaat ctttaataaa acttgttatt
     4561 tttgaatgtt gcaaatatga aatatggaat atgatatctt cagatatata atccctttct
     4621 gacggaaact tgatattgtg ctgttgaatt atctcagatg aatacagcgc atgccaaact
     4681 gacattggca atataaaatc gactttataa ctcggctcag tgccaatcat tccaagcaac
     4741 actttttcaa ttatagcgtt atttgtaaat atcgtactat catatcttgc tggctttgaa
     4801 ataatattat tatcatcata atattcataa tatccagcat aacatgtgtc tgcattactc
     4861 ctttttatac catttaacat tgcttcaata taattagctg caacaaaatc atcagaatca
     4921 ataaaagcaa catattttcc ttttacatgt tcaagtcctg tatttcttgc caatcccaag
     4981 ccagcattat ttttatgaat aatacgaatc cttgaatcct ttaatgcata gtcttcacat
     5041 attttattag atgaatcctt agatccatca tccacaatta taatatctag gttcttatat
     5101 gtttgattac acactgattc caaacaactt cctacatact tttcaacatt atatacaggt
     5161 atgattacac taattagatc actcgaattc atccttctat cctttcactc acgttttctc
     5221 aattagtcaa tgacggcatc aacgattttc ttaaattctc tgaaaaaaat agactctgat
     5281 cttgatgatg tgaatgacat actatcttct tctagaaaaa ttatttcctt taaattattt
     5341 attaaatcaa taatatgatc ctcgtaagta tgctttccct tggaataatg aaaatatact
     5401 tttgtattac acaatattgc aattttattt cttaatatga ttatttcact cattcattac
     5461 tgccacatat acacaactta taaccacccc ctgcaaagtt tagggtaagt tatcagataa
     5521 tatcttcctc ttcatcatcc agaatacaaa atctatttat ttatagaaat atcattaatg
     5581 tttttatata atgtaccgtg cttgtactct tgctctatta caagcactaa aacactacta
     5641 ttcatttgaa ttcttacacg gataaaaatt tacatcgtct atttcaatat tttttctctc
     5701 tattttattc acttaataag ttcattacat aatcgaaaca ttttttattt tccttgtcat
     5761 cactccttgc tccctttttg atacagattt aaaattctat caaagaaatt tccatcgtta
     5821 aatttcgtta ttgccaaatc cttcgaacaa cgtgaaaatt ttacgtattt atctttatca
     5881 ttgattttta gtattgcaga tgtcaacgct gatacgtcac caggttgaaa caaatatcca
     5941 ttttctccat cacgtactgc tgaagaaata tctcctacat ctgtagcaat tacaggcatt
     6001 ccataagaaa tcgcctctag aatagatata ggcaatccct cgttatagga cggtaaaatc
     6061 atcacatttg atcttctata gcactcctcc tttttttctc ccacaaccca acctgtaaat
     6121 tcaaaatacg attgcaaatt atattcttct atcaattctt tgagcgatat ttcttcatca
     6181 cctgctccag caatctcaaa aataaacttt ttttctggat attgttctgc aatgttttta
     6241 actgcttcta ccaaatcgtg tacacctttt cgctttatca aaactcccat aaacagaaat
     6301 cggcacattt ttgaattcca ctttatggta tattctggaa ctacaataga attttctaca
     6361 acaacagttt tacaatttgg ctcaatttct ttaattatct tcttccattt ttctccaagt
     6421 acaatcgtgg aatcagactc tcttaacagc aagcgaatct gattttgttt ttttacagaa
     6481 acactatcat accatttttt aaattccgat ccatgaagat ggatgattac aggaatattt
     6541 aataatctaa accacttatt cagcacatat ttcctactaa aactccctct gtacgacatg
     6601 tgcatatgaa taatattagg tttactcaat aaagagatac ctataatttt agcaaatgca
     6661 tacataaaat ataaagattt aaatattgca tttccaccct tataactcgg tataaaagtc
     6721 atctcgatat tctttttttc ccaattaaaa ttgagcattt gtgtaattat acttgtaatt
     6781 ccacctttta ccgagctgtc attaccaatc ataagtactc tttgcataac gctttactcc
     6841 ttatatttat attttttcta ttaatacctc tatcgaatta ataatcgttt ccgtgttaga
     6901 tacatacttg ttaaacatcc gaactcttgt ttctttaacg gcatcttcta aattttctaa
     6961 ttcataacaa ggatagataa tattcatctc atcaaattgt ctaattaact gcagttggtg
     7021 atcatcgaca tgctcaccat acttagccaa tcgaggaaca gcaatgaccc ttttaccttt
     7081 ttttacggcc ccaattatag cacctgtacc tccatgagta atcaccattt ctgctttttg
     7141 catagtttca gtaaactcat ccctatttag aaatgcttta taggaataat ttagtggttt
     7201 ataatcacta taaccactct gtgcaaatgt actttcgatt attactcctt tttcaattaa
     7261 atcatcaata gcttttaaca atctatcaaa ttgaaatttt tgtgaaccta atgttataaa
     7321 tatcattttt ttctcctatt atttaatata tcccacccaa ataaatagca ttaggataaa
     7381 attgtagcat agtttcccac tgaacataaa attgatctgc aaaatgatac atcaattttc
     7441 ctgtctgagt agggctggtt acttttgcaa acgattcaat ataaatcagt ttttttccca
     7501 tcatttttgt tattaagcag atagggatca tagctaaaac acctgtacaa atcacgagat
     7561 ccggtttttc ctttatatat ataataattg atttgaataa attaataagt atagtacaca
     7621 aaaaaaactt ttcttttcta tttacttgtc tcatgtagta cgttttttcg ccttttgact
     7681 cagctgaata ttctgtctgt tctgttataa caaaactctc atacttctcc atcagtggtt
     7741 ttaacatcat taactgttca taatgccccc cagaggaagc cgcaaaacat atctttttgt
     7801 tcatattaac ctctctatca gtcacgctga aaaatatctc tagtgtaaac tttttcttta
     7861 atatcatcca agcaggtatc atatcgattg gcaataatag aatcacacat cgccttaaac
     7921 tgctctaaat cgttgataac cttacttccg aaaaaagtct ctccatcttt cagtgcaggc
     7981 tcataaatca ccacagtcgc acctttagct tttacgcgct tcataactcc ctggattgaa
     8041 ctctgacgaa aattatcact gttgctcttc atggtcagcc ggtatatacc gattaaaact
     8101 ggattttccc tgttgacatc atactgatta tattcagcgt agttgtaata gcccgccatc
     8161 tgaagaacac gatctgcgat gaaatcctta cgggtacgat tagattcaac gatagcctca
     8221 atcaaatttc caggaacatc tgcatagttt gccaacaact gcttggtatc ttttggcaag
     8281 caataacctc catatccaaa ggatggattg ttgtagtgag ttccaatacg aggatcgaga
     8341 caaacaccat tgattatctg ctgagtattc agccccttca tttcagcata agtgtctaat
     8401 tcattgaaat agctgactcg cagtgctaaa taggtatttg caaacagctt tactgcttcg
     8461 gcttcagtga atcccataaa aagagtatcc acgttctcct taattgcact tttctgcaga
     8521 agtgttgcaa aaacatgagc agcatttaac aagcgctcat cagtcatatc agtaccaaca
     8581 ataatacgag atggatacag attatcatat aaagccttgc tctcgcgcag aaactctgga
     8641 ctaaaaataa tgttcttact ccccgttgtc tcacggactg attcagtgta gccaacagga
     8701 attgtagact tgatgaccat gatggtatca ggattcacgt ccatcacaac ctcaataact
     8761 gactcaacag cagaagtatc gaaatgctga gtacgactgt catagttagt cggtgtagca
     8821 ataacaacga aatctgcgga tttataagcg ctccttgcat ccaaagtagc agttaagtca
     8881 agttcttttt ctgtaagata cttttcaata tattcatcct gaattggaga cttccgttta
     8941 ttaatcagtt caatcttttc agggataatg tctaccgcgg ttacctggtg atgctgcgcc
     9001 aatagtgtgg cgatactcaa accaacataa ccggtgccgg ctactgcgat gttgtacttt
     9061 ttcttcacaa tatctcctct ttcctctctt aagtatggag aatgttactc ctacggctat
     9121 tcatcatgtc aaaataacac agcttagaat gttgataaaa taattttcca gaatgtgata
     9181 aaatctcttt catttataaa ccacacatct aattttatct attctccaca agacatgtag
     9241 agtattcttt aataacaaga tacgacctta ctaaatactt caaaaaatta tcatatttaa
     9301 ttcataaata taaatcttca ttttaaatgt atgcccaaaa atttatctgt aatgcgtcat
     9361 caaaatctag attccaaatc tttatcaatt tttatccact cattctacca ctttagtaat
     9421 attttctatt tataacactt tcgtcctaca ttgatccccc cctctgaagt acagttttta
     9481 ctgtcttaaa taaaatttta aaatctaacc ccatactcca attttttata tattccgtgt
     9541 caagttttgc tacttcttca aaatcagtaa tatcacttct accacttacc tgccacattc
     9601 cagtaattcc tggcttaata gcaattcttg cacgatgatg ataatcatat tcttcatact
     9661 ctgatttaag gcatggtcga aatcctataa ggctcatctt tcctgttaga acgttgaaaa
     9721 attgagggaa ttcatctaaa gacgtggatc taataaattg accgattcct gtcttttttg
     9781 ttccatctgg aagtatttta tttccgataa ttcttggatc aaactccatc ttaaacataa
     9841 gattattgct catcttattt tctttcatta attctacttt tctttcttct gcatccatat
     9901 acatacttct aaacttatac atcttgaacg gtttaccatt ctgacctata cgttcttgtg
     9961 caaagaaaat tgggcctggt gaattaatat aaataagtgg agcaataaag ataaaaataa
    10021 ttcccgttgc aatacatcca acaatacctg caagaatatc aattgttcgt tttataaatg
    10081 cctgttgagt tgtcataaca ttgatacttg ttgtaagtac tgtatattct cctatacgac
    10141 caatagattg ttttcccaaa gcactatctg atacttttgc aagattcaaa tgtacagtaa
    10201 ggcccatttc agagcatcgt tcaataaatt ctttcataca cgaagtactt ttattcaaaa
    10261 taataaagac ttcatctacc catccctgac ataagtaatc cgctgcattt ttggaatcag
    10321 aaacaactgt cactccctca acatcttcac caatcatgct tttatctatg ataatgacac
    10381 catttatttt atacatttta tagttatgct ctttcacatt acgaataact acttcagcaa
    10441 tactactaga tgtaactata ataagtgatt tgttcccctc atttttcatt ttatgtttca
    10501 agtaatgttt ccataagagg cgagttatat atgtaattac aacgtataaa cctcccatca
    10561 agaaaagaac gactctagaa taatcatttc caccctgaac actaatgaga tacaaacttc
    10621 ctaacagcac caacataatc gcttgcttta cagaagaagc aaattctata tagtaccctc
    10681 tttttaatac acctctatat gcttcaaaca tgaaaataac taaaagatct gccagttcaa
    10741 tgaagactgc catgttttga tacattggaa tcacataagg attccaatct acctggcgta
    10801 agacatacga tagataaaaa gcaagctgga tacacaataa atctaaaata ataaaatcaa
    10861 tatgtttaac ccatcccctt gaacttttct tgtacattcc tttttactcc cctcttttta
    10921 ataaaataaa ttgtattact tgttttctct cctaaatatc tttctgaagg attattgact
    10981 cgacaaattg gcttgtggat attcttatat atagaacatc cgtaagccaa cttaaaactc
    11041 cttaacaaaa tttttttact catattgtag atcaaaacaa gtatccaaga aatcatattt
    11101 tatttctttt ttctgcttac tcaacaacag ctaaaagaaa aatcatcata aacaaattca
    11161 actaagccaa cgatcccctt gtgaaatcaa gttttttctt gatttacgaa taaagagcta
    11221 aaataaacca aacttcttct tttttacctc ttcatagact ggataactga tttcatcccc
    11281 gttgatcaga tcctttgcga cttgtttcat ctgtactact ttttccttac caaagtcctt
    11341 tgcaatctgc tcatagcact cttttaagta aaaggtgcgc ttagagaccc catgggcatc
    11401 agaagcagcc atctgcacga gattatgttt gaccatcgtt ttggctgttt tctggatgtc
    11461 tttgccaaat accccaacat aacttggcgc agtgagttgg gccaaacatc ccatatctag
    11521 gaacggaagc aaatgatttg ggtcttcgcg aaaatgcacg ttgcgttctg gatggacgat
    11581 tactggtgtc tttcctagtt ctaacaactc aaaaaaaagc cgttctgcat ataacggcac
    11641 ttccagtgtc ggaaattcga tcagaagata tgtatcatct aaatctgtaa ataatatttc
    11701 atctcggtgg atgtcttcga tgagcgttcc ggtaatacgt acttcttgtc cttccaataa
    11761 cgtcaaaggc aactgtcttt tctctaattc ggcttgtaac gaagcgacta gagaaatgac
    11821 ttgtgatttt tcattgctgt attttccatt attgtggtgt ggtgtgcata aaatatgcgt
    11881 gatgccttgc tgaatcgctt tttcagccat tgcaatactt gcttctaagt tttctgcccc
    11941 gtcatcgatt cctggtagga tatggcaatg tagatcgatc atttctcttg tctcctctct
    12001 tcttattcct taatttccgt agtaataacc agcatctttg ctatgttctg ctccgttgta
    12061 cacaacacct aagactcgtg cttgtaccat ctccagcagt tcttttgctt tagtcaagga
    12121 ttctttacgt gacatatttt cacgtacgac caataaagtg ccatccgttt ttaaagacat
    12181 gatctgtgca tctgttacgg ctactactgg tggcatatcg aatatcacca cgtcaaataa
    12241 ctgtcttgct tcggatagga tctgatccat tcttggcgag cttaacaatt ctgatgggtt
    12301 gggtggctta ggtccactag gcaaaatcga caagttctcg actggcgttc gttggatcac
    12361 atctgctaca cttcctgatg aactaagtgc tgtacttaat ccactggcat tgttcagctg
    12421 gaatgtctta tagacgacgg gtttacgtaa atctgcatcg actagtagaa ctcgttgacc
    12481 tgatttagca aaaacgactg caatgtttgc tgcagtggtg gatttccctt ctccaggacc
    12541 tgatgaagtc acgacaatcg ttttgatttg ctgaccagct gcggaggcaa actggatatt
    12601 cgtccggatc gtacgatatt gttcggcgat tggtgaagat gggtttgtta atgtgatcaa
    12661 actgactgca tgagtttgtg ctgctttttg tttctgtgtt cgtgccattt ttcttcctcc
    12721 tagactcttg agcggcttct gcgtgatggg gctgttttat cgtttgtagc ttttggtcgt
    12781 gcaggagctg ttcctttttt acggatacca gcgttcaatt ctttcgctga catttctgga
    12841 actgttccta agattgggaa tcctaatgta tctgtcacat atttttcatc tttcactgtc
    12901 cgatcgagta attccaataa gaatgccaga cctacaccta ccatcattcc taacattaag
    12961 ccagtcatta aattcaattt attatttggc gaaacaggtg tcgtattggc aactgcacct
    13021 gaaatgatcg agattttatc aacattcatc acatcttttg cgttctcttg gaaaacttgt
    13081 gaagttgtgt tagcgatctg ttgagcagcc actgcattcg tacttattgc ctgaatcgag
    13141 aacatttgtg aattttctgc ctgattaact gagatggcat ctttgatttg ttcagcagtc
    13201 attttcacat tgtcttctgt ttctaaacga tctttgactt cattgagcac taaatcactg
    13261 acgatcatat ctttatacgt attgatcatt tgcaggttcg tattgacatc attgacattt
    13321 gcagtgtctg attgtggcag tgtcacgatc aattgtgctt gtgaactgta ttttggtgtc
    13381 aagatgaaaa atgttacgat tcctgagatg gccaagccag caaacattga gatgatgatt
    13441 attaccaagt gtttgcgtaa tgtttcaaaa atttctttca agctgattgt ctcttccatt
    13501 ttttctccac tttcctattt attctctaga ttcatttgat cttttaattc ttttttcaca
    13561 cgatcaagtt cttgatcact gactttttga taggagatat tatcttgcat gaagccttct
    13621 ccttgcagct gatcttgctt aatcgtacca aatgcctccc gataatctaa agcaattttt
    13681 ttcatttcat caaagttcat gtctgttttc atattcgact ctagagcatt caaaacggat
    13741 tgatagttgc tgacaccgtt tagactcaat acttttttcg ctacgccttc tacgatcttt
    13801 ctttggcgcc cttgtctacc gtaatcacca tttgggtctt cataacgcat acgagaataa
    13861 gataatgcct gatccccgtt caatgtaatt ttaccgattg gaaagtcata gccatcttgt
    13921 gagaaagtga ggtcattatt gacttcgata ccaccaactg catcaacgag ttcctttagt
    13981 cctttcatat tgatagagac atagtgatcg attgggatgt ctacatattt ttgtacggta
    14041 tccatcgcca tggcagctcc gccgaatgcg taagcgtggt tgatcttgtc ttttgtgtca
    14101 cgacctacga tgtcgacata cgtatctcga ggaatgctga cgatcgttgt ctgtttgtct
    14161 tcaggactga ctgtggcaac catcatcgta tctgatcttc cttgatcgac ccgacctaaa
    14221 tctccagtat caatccccat caatagaaca gagaaagatt cttgtttgtc cagatcaact
    14281 ggtttcgttc gttctccttg ggttcgttcc actgattcgt aagttttctc aatagaatgt
    14341 gagagatcca gatataattt tgctcctact cctacaattg ctaatactaa tacgataaga
    14401 actgctaaaa taatcaaaaa tatttttttc cctcttgatt ttcttcttcg tcttgccata
    14461 gtttcctccg tttgctaacc ttgcttgaat caacgtttta actgtcaata gcttatattg
    14521 ctatagccca tttgctgagc aacagtttgt gcttttgttg cgtatgcggc tcttattttt
    14581 tcattccgga tctgctctat ttgactgagc gccgtcaaat attgatcgta agtagcggta
    14641 gctgttactt gaccgtcttt cagcatcgta tcgaatagct gatctagttg cgtgacttgt
    14701 gcaatttggg tatcagcgaa tcctagatat tgcataacga ctgttttcca agcactatcc
    14761 ttaaaaaagc tcatattttc acgtacatgg gcgacatctg cacttgccaa cttttctttg
    14821 atgatgacat catccacagc ttgctgccag tttgatacgt ttttagtaaa taatttattg
    14881 acagccgtct ggatcttcag ttttgattct gcatcctcta actgcgttaa gactgctttc
    14941 ttttcttctt ggatcgcagc agcttcttta ggtaattctg attccttgat gtcataatca
    15001 tctgccgaaa gtttgataga agatagttta tgtgacaaat ttgaaactgt ttcttctgtt
    15061 atttcaggat ttaggaaaat tttttctttt gtactgtaca gcttatctac ttcttttgat
    15121 aaagaggtca cggtgtcttt ttgattggtg atggcagatt ctgcgtaatt gatccgttga
    15181 tgatattgcc gctgattatt gagatggtat ccaaacaagc aaatcacaat agcgcctgtg
    15241 cctaccgcca cagtagccaa taacttgacg aacggctttt ccatagattc actcctaaat
    15301 attgatgata gataagtaaa gatgtgattc attcacatca gaatgagcgc tttttatttt
    15361 aaaagcataa ttaaactaat atattcatag aaatatttat aaacaggttt tccctatata
    15421 atcataccac atacagtttt tttgactagg gaaattccta atttaaaagt aaataaaaca
    15481 gtaacaagat tataattaat cgttttcatt tttatttcct cacttttcat gagcgttttg
    15541 aaaattcgaa caaagaataa aataacaaaa attattaaaa tagaattaat aacagctatt
    15601 tataacaaaa aaaacagaga cacagcacgt ttcgtgcatg ctctctgttt ttcaaacaaa
    15661 agactatttt gtgatgattt gatccaagct tgctaatgac aaagccatgg cagctatttg
    15721 acttagttgt gttagtcggt tcttacgtac tgctggttca tcagccatga ccatcgtttg
    15781 atcaaaataa ttttcgatca gtggacgaag agcgacaagc tggtcgtagt tttcgtggat
    15841 cgtttggtca gcaaaacttg ctttcattgc ttctactgct ttgtgtaatt ctttctctgc
    15901 gtcgttttcg aacagctcag ggtctacttc tgattgtttt tcaagctgcg cttttttcgc
    15961 taagttcacg acacgtgtca aagcttccat tgaaggtttg aagtcttcat ctgcaagatg
    16021 ttgtttgaac aattgtgctg ctgcaaatac ttttgtcaga tctttttgtt ccgcattcaa
    16081 aacagcatcg atgacatcat gacgaatatt cttcgttgtc aataattggc gcagacggcc
    16141 tttgataaag tcgatcactt gttgttgccc ttctgataaa ccaatgccga aacgatccgt
    16201 atctttactg ataacatcgc taatcgtttc ttgcagaaca gacaaaggaa aggcccattt
    16261 tttcgattcg atgatccgaa cgacaccgta tgcttggcga cgtaaggcat aaggatcgtt
    16321 tgacccgctt ggaatcatcc caactgcaaa gaaagaaaag atgctatcta atttatctgc
    16381 aatcgctaaa acagaaccta ctgtagactg aggtagctct ccttcactgg atataggcat
    16441 gtaatgctca cgaatcgctg tcgctacagc aggtttctcg cctttcagaa gagcatattt
    16501 ttcgcccatg atcccttgta gttcaggaaa ttcccctacc atgttggtta ctagatcaaa
    16561 tttatagatt tcagcagctc gttgcaaatc catcaattct tcctcagata gtcctacttg
    16621 ttcgccaatg atacgggcaa tgacttgtac ccgttgcatt ttctcataga tactaccgat
    16681 tttttcatgg aaagtaacag tttttagttt ttcaacgtat tggtcgattg aagctttctt
    16741 gtcttcatta taaaagaatt ccgcatcttc taaacgagcc gtcaatactt tttgattgcc
    16801 tcgaaccaca tcttccaatt ttacccgatc accattacga gcagaaataa aatgaggaag
    16861 cagcatacct tgatcattcc gtacctcgaa ataacgttga tgttctttca tagaagtgac
    16921 tagtacttct tcaggaacag aaagatattt ttcttcgaag tcgccagaaa agacagttgg
    16981 atattcgact aaattgttga cttcttctag taaatcttcg tctagatcaa taacccagtg
    17041 atttttttct gctaattcgt ttgcttgtgt aacgatcatt tcttgtcttt tttgcggaga
    17101 cgcaatgacg aattgttcat tcaatttttc ttcatattct tttgcatgcg caaatgtcac
    17161 atcttcgcct aagaaacgat gacctcgaga ggctctgcct gttttgacat ccaagatttc
    17221 gaatgggatt acttcgtcat ctaacaatgc cacgatccag tgaatagggc ggatatattc
    17281 aaaatcgtat tctgcccaat gcatcgttac agggaaagtc aaacttttga tcacccctgc
    17341 taagcctgtc aatacttctt ttgcttcctt accatgagtg tatttcgtta catagacata
    17401 ttccacacct tttaattctc taaaagtgat agcgtctgtc gtcagacctt gtccgcggac
    17461 aaatccttcc gctgctttcg tccagtttcc atctgcgtcc aaagcaattt ttttggctgg
    17521 tcctttgact tcttcttcac tgtccgcttg tcgttctgga atatttgtta ctttgattgc
    17581 taaacggcgc ggtgtggaaa atgtttcgat cgtatcataa gtcaattggt tttcatctaa
    17641 aaattttgct gttttttctt ctaattgttt catgcttggt gtgacaacat gggcaggcat
    17701 ttcttccagc ccgatttcaa gtaataagtc ttttgccatc ttattcagcc tccttcacgg
    17761 tttctggatt tgctgtgttt ttattcaaca aagggaatcc taatttttcg cgttctgcca
    17821 caaagatttt ggctacagca cgagccatgt tgcggatgcg agaaagataa ccggcacgct
    17881 ctgttacgga tactgcaccg cgggcgtcta ataagttgaa tgtatggcta catttcaaga
    17941 tataatcata cgccggatga acaagatttt catcgataca gcgtttagct tctttttcaa
    18001 aacgatcaaa gttgcttagt agcaagtctt ggtcgcttac ttcaaaagaa tatttggaat
    18061 gttcatattc tggttgtttg aagatctcgc catatttcac gccatcagcc cattctaaat
    18121 catagacact ttcaacttct tggatataag aagcaagacg ttctaatcca taagtgatct
    18181 cagaagttac tggtttacaa ggcagtccac caacttgctg gaagtacgtg aattgtgtga
    18241 tttccattcc gtcaagccat acttcccaac ccacaccggc acagcccatg gatgggttct
    18301 cccagttgtc ttcaacaaaa cggatgtcgt gttctaatgg atcgattcct aaaaggcgca
    18361 agctttctaa ataaagctct tgaatattct caggtgaagg tttcatcacc acttggaatt
    18421 gatgatgctg atacaaacgg tttgggtttt caccataacg tccatcagct ggtcggcgag
    18481 atggctctac gtaagcagca ttccatggtt ctggtccgat tgcccgtaaa aaggtatatg
    18541 ggctcatcgt acctgctcct ttttctgtgt cataagcttg catcagcatg cagccgtttg
    18601 atgaccaaaa tttttgtaat gttaaaatca tatcttggac ggtcaatttt ttactcatct
    18661 gttttgcccc tttcaatttt aaagcgttgc tgtcaaataa gaatacagga aagaaaacga
    18721 caaaaaatcc ctatgtctga ttacagacat agggacgaat aattcgcggt tccaccctac
    18781 ttccgaataa agattcggca gcttcattta tcgtactcgc aagtgcctct tcaaaaatcg
    18841 tttgggtccg gctcccactc tcccgaactc gctaaaccac gtgtttttta ctgatcttgg
    18901 tcaatgtacg tattcatttt gcagttttct tgtttctata atagatccta tcactgaacg
    18961 atctatttaa tctatggtta ataatagacg gaactccctg tgtttgtcaa atggttttga
    19021 ttttttgttg tatgttttat ttactattct tctttttcag gtgtctcttt ttctttttca
    19081 gacatgtctt tctctgacgt ctttaatacg tgtgcccaag acttcatttg attgatgaac
    19141 tttttgcttt tcaaatggat accgacatat tcatcataca gctggtcgat gagttcacgg
    19201 attgcttgtt tggtttcttc tttcagatgg attccactaa ttttatcata agaaatagct
    19261 gaaaacatcc gaacgaaata aacagctcga ggatctgcat gataacggtg atcgtccatc
    19321 gaccaatgtc tttcgcatat cacaccacca tatttggaag aatagtcaaa ttttcctttt
    19381 gtttccccgc atacgacgca gtgtgtccag attggtgcaa ttccgaagcg ttgcagtatt
    19441 tggacttcaa aaatattcgt gatgatttct gcatcgtctc cttggtccat ccgttgcagt
    19501 gcttgttgcg taaactggaa caaatgcggg tcgtactgat gatcttcgat tgccgcatct
    19561 actagattca ataaatatgt gccatagccg ctcaaaaaga tgtcttcttg gatgtgtcga
    19621 aacgcatgga catctttgac actgcttaaa aatgacaaac cttcacttcg aaaattcccg
    19681 atataaactg cttcagtaaa agggagcaaa gccggagcta agggctgatt ttgccgatgg
    19741 atctctttga tataaaacat cattttgcca gaagattctg taaagatttt gactaattta
    19801 tctttttctt tgtaattacg gctagataaa atcaagcctt ttgattctgc aagctggctc
    19861 atattctccc tcctaaaaaa taaatctgga aaagcagatt ctgccgatcc agatcattta
    19921 tgttgcgatc ttccgcagct tttctcaaca cgcggatttt tattcagttt atttctatac
    19981 ctaatttaca agaagctcag aatatcagta ttcgtctttt cggtagccga agtcttgcag
    20041 atagactttt ttgtctcgcc agtctttttg aactttgacc caaagttcta gaaagacttt
    20101 gtctcctaaa agattttcga tatcttttct tgctttcgtt cctacttgct tcagcatttt
    20161 tccgcctttg ccgataatga tccctttttg gctatctctt tcgacaataa tcgtagcctg
    20221 gatatggatt ttatcattct cgtttcgctt catcgaatca acaacgactg cgacagaatg
    20281 aggcacttcg tctcgtgtta aaaacaagac tttctcacgg atcaattcag aaacgatgaa
    20341 gtattcagga tgatcagtca cttgatcatc tggaaaatat tgtgggccct ctggcatttc
    20401 actgactaat acatccatca aacgttcgac gttgtttcct tctgtagcag agattggaat
    20461 cacttgtgca aaaggcatct gcgttgaata atcttcgatg attcccaaca actcgtctgg
    20521 atggattttg tcgattttat tgataatcag ataaacagga gaatgcacgt tttttagacg
    20581 ttcaataata aaatcgtctc cccgaccgcg tttttgatca gcactaatca taaataagac
    20641 cgcgtccact tctttcaacg cactgtaagc tgcttctacc ataaaatctc ctaaacgatg
    20701 ctttggttta tggattcctg gtgtatcaat aaaaatcaac tgagcttctg gtgtagtgta
    20761 tactccttgg attttatttc tagttgtctg tgccttgtca ctcatgatgg caattttttg
    20821 acccacgatt cgattcaata atgtggattt ccctacattt gggcggccga cgattgcgac
    20881 aaaccctgat ttatgttctg gcatatatgt tctccttttt aattaaacaa caaatgatat
    20941 attttaggga caaataaaat caacccaacg atgacggtaa aacaagcggt cactaaaact
    21001 gctccagctg ccatatcttt gatttttttc ccaatcggat gaaaatgaaa atccgtaaac
    21061 atgtccacga cattttcaaa aacagtattg atgatctcta ctatccatac gagaaaaaca
    21121 gctaaaagca gccataacca ttctatccga tcaagttgga aaatcacgcc cataaacaaa
    21181 gcgaggattc cgaacgcaac atgtttcctc atgttgcgtt cttcctcaaa aacagttttg
    21241 actccttgga cggcaaattc cacggacatc aggaaatgtt tgtttttctc tacgttttta
    21301 tcttttaagt ccataggcat ctaagatctc tttctgtaaa ccaaacattt ctttctcatc
    21361 ctctggtgtc atatggtcat acccgttgat atgcaagaat ccatgaaccg ctaaaaagcc
    21421 aagttcccga tcatacgaat ggccgtaagc ttctgcttgc tctgcagcac gttcagtaga
    21481 gatcatgatg tctcccagta cacgaggcaa tggattctct ccatcttcaa aaatcactgg
    21541 gatttcgtct tcgccctctt cttccaaggc aaaactgatg acgtctgtcg gtgcatcttt
    21601 tccacggtaa tcacgattga ttacttggat tgctgcattg tccatgaaag taacagacat
    21661 ttctgtttct tctggcaact ctaaatatga tgctgcaaat tgcagcaagt cgtcgatttc
    21721 tttcattttc tcttctgaga cttggtttgt ttcatccatg aaggtaatat ccattataca
    21781 tcgcttcttt ctattcttct tgctattctt cttgttcttc ttttatcttc tcaacttccg
    21841 atttcatttt aggatatttg atccgagaat ggaaggtact gcttaaaccg ctgatcaatg
    21901 atttttctac tttacggatt tcttttaacg tcaatccact gtcgtccaat tgtccatcgg
    21961 aaatacgctc ttcaataaga ttatggacaa aactttcgat tttttcgctc gttggatggt
    22021 ccattgcccg tactgccgct tcacaactgt cagctatatt gacgattcct gcttcacggc
    22081 tttgaggttt tggtccagga taacggaatt gctcttccgt aacttccggg ttgcgttcct
    22141 ttgccttaac gtagaaataa cgcatcagcg tggttccatg atgctgtcta caaatatcga
    22201 tcaccatttg cggcatatta taatcttcca atattttggc accatctgtc acatgtccaa
    22261 agataatatg tttactgtct tctggcaata agaaattgtg cggattttcc gctcctgaag
    22321 gcaagttctc aacgaaaaag ctggcgtgtt tgatcttgcc gatatcatga taatagcaag
    22381 ctactcgagt tagtaaagaa cgtccaccga tttctgctac agcattagca cttagattgg
    22441 ctaccatcat gctatggtga tacgtacctg gtgcttcttc cagcaactgt ttcaataaag
    22501 gatgattggg attgctgagt tcatttaata cgatcacact atcatcattg accatcaatt
    22561 caatataggg gtgcagacct atcgtcagca agaatgaaaa cagtgcacct gtgaatccgc
    22621 agactagcgt taaccaagtc gttgcatccc caaagctcat tccttggtag ataatcaaaa
    22681 tgacatccat catcacagga aaaataatga cccacatagc agcggataac ccttgttctg
    22741 agatccgttt gcgtctgacg atcgttgcca tgagaccaga aaatacatag gacatcaaaa
    22801 taactgtcag aaagttcgtg ccaatcgaat cataaaaaat gaaaagtgcg gatactgctt
    22861 gaaaaatacc agccatgatc cctgctcttc gattcaagaa aaagcttaaa acaagtggag
    22921 caaaagccgc ggggtaaaac agcggaatat aagcagcttg ttctgtttgg aagagttgga
    22981 aaaatttcat tagtacgacg cttactgaca ttgccgtcac gtagaaaagt acgtattttg
    23041 ttctttctcc tgcattttgg aattgaagtg aattataaat cagtacaccg atttgaagca
    23101 aaacagctaa aaccatggca atgagtggga aaatagaagt cgtttgattc gtcaatccta
    23161 gtaattccaa ttttttcatc gctgaagcat caatttgatt tccttcgcga acaataattt
    23221 ctccttggaa gatcatcact ggttgtacag cttctcgtgc agattgtttt aattcttctg
    23281 tctttttctc attcaataca tcattaacta cgatgccttg atccactaag tagcgaatca
    23341 tttgttgctg ctctgttgtg acattcaaat attgaatctg atcttctgct tcttgtttaa
    23401 aagcttccaa ttcgctttca cgaacttgtt tactcatctg ttcgtcaatg agcttcaaac
    23461 tttcatccct aactgtgtga atttccgttt cagtcatttc aaatatcgtc gaataaaaat
    23521 tgttcggcag tttttggtaa aacgcaacgt tttctgcatt cacgttttca aaatttttct
    23581 tcagtgtagc aatccgctct tctgtagtag gtttcgggat attttcatct tccttcgcct
    23641 tatctacctt gccattataa gatttgttga tggtatcatt cgtcttatcg atcaattcga
    23701 ataattgctt gatccgattg ttctggtcat ctgccagatc tttttgataa gtatattctg
    23761 gagtcactgc ttctgctgcc agttttcttc tttgttcggt ttcttccgtg ttctcaatcg
    23821 ttttattcgc acggatactc tcttctgcta cttggccttc tctgaaatca atggcctttt
    23881 gtttgacact actaaatgta acgccgcaga caatgataaa aaacaagaac agaaggaaag
    23941 gcaatgctgc ctttccgagt ttttcttgta gtttctgcag tgttttattc aacatgtgct
    24001 tatcctccta agcaaagctt attcttgatg aagatccgcc ttttcataag ctttgatgat
    24061 ttcggcaact acagggtgcc gaacaacgtc acttgcttca aaattaacaa aatcgatttt
    24121 tttgatttgc tttaatgttc gttctgcatg aacaagacca cttgtcgtcc cacgaggcaa
    24181 gtctatctga cttgtatccc cattgacaat catttttgat tgataaccga gacgggtcaa
    24241 gaacattttc atctgagcga ctgtcgtgtt ttgtgcttcg tccaagataa cgaatgcatc
    24301 atccaatgtc cgcccccgca tgtaagctaa aggtgcgatt tcgatcacgc ctcgttccat
    24361 caatcggttc gtatgatcca atccaaaaat ttggtataaa gcatcataaa caggccgcag
    24421 ataaggatcc actttttctt tcagatcccc gggtagaaag cctaggtttt cccctgcctc
    24481 cacagcgggc cgcgtcaaaa tgattttttg cacttcgcct ttttttaggg cagcaattgc
    24541 taatactacg gcaagaaacg ttttccctgt tccggctggc cctacaccaa atacgatgtc
    24601 atgtttggct accgattcaa cgtatttctt ttgaccgctg ttttttaccc gtataggttt
    24661 tccattacgg tctttgacga tctcttcctc atacatctca acaaaataat ctaatgtacc
    24721 tttttgcccc attttcaatg ccgtcacaac atctggcgta cttacgtgga ttcctcgttt
    24781 gatcaattcc tgtaatgtcc gaatgactga ggcagccaag gaaatctggg attgctcacc
    24841 aatgatctga atgatttctc cacgtgtatg gatggttgtt tccgttgttt cctcgatcag
    24901 ttttatatgc ttgtcgtgtg cacctaaaag catgctgaca tcatcagcag ctgtcaatct
    24961 aatctctaaa gaactagact cttccgtcaa aaatagacat cccctttttt tcgattcatt
    25021 ctttcctatt ttaccatact cagaagaaac tatatagcaa ataagaaaag gttgtaaaag
    25081 agtcgcttaa ccatacgtac caagaaacgt taaaaaatag ccgtttccat tcgctaaagg
    25141 tctcgttttg ataaaaagaa gctgagaatg taagttatat gaaagtggag aacaaaatat
    25201 ttcgtttcat tcaacaagta ttctctaggt atttttcctg tttcaaaaaa agaaaacaaa
    25261 atagttaaaa tattcttgca tttcaaaaaa aacaggtgta ttattacgtc aacaaataaa
    25321 catacagcaa agcgtcgagg aaaacagtag gctattcaac gatttattcc cagtgagtca
    25381 tgtaagtgag aaatgacaat aaatcgaata gacgaacatc atttccgagt caatgtcgaa
    25441 aacgtagatc attgtggctg cctccattat caggctagcg gataacttta tcaaaaagcg
    25501 tccgtgaatg aagaagcttt tttaagcgaa aaaaggtggt accgttctag aatctagagc
    25561 ccttttccca agtggaaaag ggcttttttt tattttaagg tggtggtttt catggaatct
    25621 gatattagtg gcattactaa ttgctgcaac gtttatatcg tcaatcaaaa tgataattat
    25681 tggaggaaaa atttatggaa gaaacaaaaa cttattcatg gaaacaacta ttgatggtca
    25741 gttcacttat cttcgggatg ttcttcgggt caggtaatct aatctttcct gtccacttag
    25801 gtcaaatggc tggcgcaaac tgggtcagtg ctggcgtagg atttgctatc tcaggtgctc
    25861 ttttcccatt actagctatc ttagctgtag tagtgacaaa aagtgatggt ctgtatgact
    25921 tagctaaacc tgtcggaaaa tggtatgctg ccttgttctt aatccttgtt catttgacga
    25981 tcggaccatt tttcggtaca ccacggacag ctgctactgc ttttgaaatg gctgctaaac
    26041 catttttgcc tgaaaaatat aattcattag gtatgttttt attctctgct cttttctttt
    26101 tacttgctta tttccttact gtccatccaa cacggttggt caaatacgtc ggaaagtatc
    26161 taaactcctt gtttcttgca ttattagcaa tcatttttgt cgtttcttta ttccatccaa
    26221 tgggaaatct aaatcaatct gctgcagata cttatcaaac aaacgcttta acaaatggtg
    26281 tcctagaagg ttataacacg gttgatgcag tagctttgct tgccttaagt gtcacttttg
    26341 tccatgcagt ccgtgacctt ggtttcaaag ataaaaaagt cacagaatta acggcaaaag
    26401 ctggtagcct gagcgttgcg ctagaagtca tgatctattt tggacttgtt cttctcggtg
    26461 cgatgagttt gaataagatg tctttatcag aaaatggcgg aactgcactt tctcagatca
    26521 ctaattttta tttaggtaac ttcggcgcta gcttcttagg agtgatggtc acattaggtg
    26581 tcttcactac cgctatggga ctcgttgttt cttttgcgca agatttccat aaactgttcc
    26641 ctaaagtcag ttatatgaca tggctgcggt taacgacttt cgtctctttt gtcgttgcaa
    26701 atgctggttt agacaatatc atccaatggt ctttaccagt attgatgctt ttgtatccat
    26761 tgtcgcttgc gttgatcttg ctttccttaa cagcaaaatt tttccaaaag acaccatttg
    26821 tctatcaagt aacgatgttg tttgctgctg ttcctgccgt attggatatg ctggcaaatt
    26881 cgcctgcttt agtgagtcaa caaagagttg tagcaagcat gctcgaattt tatcatcatc
    26941 acgttccttt tgctgcatta ggacttggct ggatggtccc aacgttactt ggttacgctg
    27001 gcagcctact gttttattac gcctatcgcc tatcagggta taaacaagaa gcaaatgaac
    27061 taccagaaga ataaccaaat caaacacaat ttaacataag aaatattaaa caggaaaaaa
    27121 ccagctagat gaaagaatcc tattctttcg tctagctatt ttttagttct cttttttacg
    27181 cgcacaaaaa aactgcggac aatgattgtc cgcagtttaa atgggctcta taatatctag
    27241 tgttggtgac gccttctgtt gccaatactt tttctttttt ctaataaacg caaacagaca
    27301 ccttgaaatc ctttagaata aagtcgacga aaaccattca aaggagtgtt tcaagatgtc
    27361 ctattcagag tttaccaaag agttactaga tattctagac ctaaatctta tctttcatga
    27421 agatgccttt cgcaaagagc gaatcaatga cgaaacatgt tttgtttttg atggcacatt
    27481 gacctatcaa ccagaggaat gcttccattg tcactatcaa aataagcaaa cgatcattaa
    27541 atggggctgg aaaaaagtat ccatcttatt gaatgatgtc agtaactaca agaccattct
    27601 gcggattaac aaacagcgct tcaaatgtaa acactgtgga aagacttttt tagcagaaga
    27661 ttcagttagt gatcgtcgct gctccattgc tcgcagagtc aaacaagcca ttcttgagct
    27721 attaagcgaa cctctttcta tgtctttgat cgcacgtatg aagcacattt ctccgaccac
    27781 tgtcattcga atacttcgca gccttcggcc taaaaccgtt tctttgaacc agccgttacc
    27841 agaagtggtg tgtttcgatg aattcaaatc ggtgaaaaac gtctcgggag ccatgagctt
    27901 tgtcatgatg gacggcaaga cccatcaact gattgatatt gtggaaaatc ggcaactaaa
    27961 tcctttacgc gactatttct tgcgctaccc tagaaaagtc cgtgaacaag tacgtctagt
    28021 ggtttcagat ttctatacac cctatcgcac attggtgaaa gagtgctttc cgaatgcccg
    28081 aatcgtcgcc gatcgctttc atattagcca acacatcggt cgggccttta ccaaccaccg
    28141 aattcaagta atgaagacct ttaaaaaaag ggatcgtcgg tcgaagcact taaagaaata
    28201 ctggagacta cttcaaaaga atgcgtggga attgaaaggt cagcatcgct actggcgtcc
    28261 gtcatttcga gatcatctga cagaagcaga gatagtcgat cggctattat cttatgatga
    28321 ctccttaaag cgaggctacg aagtctacca ggattttctt tccgctatca gaagacaaga
    28381 tgttcctgaa ttcgtcgcgc tcctaaaaga agactacaag gagttgccag agcactacca
    28441 accagtgttc acgaccttca agaaatatcg aacagaaatc aaacgagcgt tgcgagttcc
    28501 ctattccaac ggccctatag aatgtttgaa caaccatatc aaagtactaa aacgaattgc
    28561 ctatggcttt agaaactttc aaaactacca agaacgaatc tttttatatc gaggaaaata
    28621 ttttaagaaa actaagaaca ctacccaact gactaaagct agaacaacaa cacggctaga
    28681 caagatagct gtctagccgt gtgagtatct cgattattct attgaat
//
LOCUS       DADLIO010000030        28601 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.030, whole genome shotgun sequence.
ACCESSION   DADLIO010000030 DADLIO010000000
VERSION     DADLIO010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28601)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28601)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28601
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.030"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            237..1877
                     /locus_tag="JOX41_001466"
     CDS             237..1877
                     /locus_tag="JOX41_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HAY6449218.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAVFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            2031..3353
                     /locus_tag="JOX41_001467"
     CDS             2031..3353
                     /locus_tag="JOX41_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HAY6449219.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(3415..3846)
                     /locus_tag="JOX41_001468"
     CDS             complement(3415..3846)
                     /locus_tag="JOX41_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAY6449220.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(3910..4746)
                     /locus_tag="JOX41_001469"
     CDS             complement(3910..4746)
                     /locus_tag="JOX41_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HAY6449221.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQAIVIVVLLINLYNAFVILQTLEGSGFKQVKITEKSF
                     FK"
     gene            complement(4936..5238)
                     /locus_tag="JOX41_001470"
     CDS             complement(4936..5238)
                     /locus_tag="JOX41_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HAY6449222.1"
                     /translation="MTEHNHSHEHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEE"
     gene            complement(5264..5695)
                     /gene="ruvX"
                     /locus_tag="JOX41_001471"
     CDS             complement(5264..5695)
                     /gene="ruvX"
                     /locus_tag="JOX41_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HAY6449223.1"
                     /translation="MRVMGLDVGSKTVGVAVSDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(5692..5958)
                     /locus_tag="JOX41_001472"
     CDS             complement(5692..5958)
                     /locus_tag="JOX41_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HAY6449224.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(6212..6937)
                     /locus_tag="JOX41_001473"
     CDS             complement(6212..6937)
                     /locus_tag="JOX41_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HAY6449225.1"
                     /translation="MSKKTTKAIVGIVAAVIAGALGISTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(7303..7373)
                     /locus_tag="JOX41_001474"
     tRNA            complement(7303..7373)
                     /locus_tag="JOX41_001474"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7339..7341),aa:Gly,seq:ccc)
     gene            7490..8242
                     /locus_tag="JOX41_001475"
     CDS             7490..8242
                     /locus_tag="JOX41_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HAY6449226.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            8258..8737
                     /locus_tag="JOX41_001476"
     CDS             8258..8737
                     /locus_tag="JOX41_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter"
                     /protein_id="HAY6449227.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(8988..10568)
                     /locus_tag="JOX41_001477"
     CDS             complement(8988..10568)
                     /locus_tag="JOX41_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HAY6449228.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(10561..11304)
                     /locus_tag="JOX41_001478"
     CDS             complement(10561..11304)
                     /locus_tag="JOX41_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6449229.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(11480..12256)
                     /locus_tag="JOX41_001479"
     CDS             complement(11480..12256)
                     /locus_tag="JOX41_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAY6449230.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(12504..13340)
                     /locus_tag="JOX41_001480"
     CDS             complement(12504..13340)
                     /locus_tag="JOX41_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HAY6449231.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(13351..14280)
                     /locus_tag="JOX41_001481"
     CDS             complement(13351..14280)
                     /locus_tag="JOX41_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HAY6449232.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            14472..14825
                     /locus_tag="JOX41_001482"
     CDS             14472..14825
                     /locus_tag="JOX41_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HAY6449233.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(14899..15555)
                     /locus_tag="JOX41_001483"
     CDS             complement(14899..15555)
                     /locus_tag="JOX41_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HAY6449234.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            15781..17715
                     /locus_tag="JOX41_001484"
     CDS             15781..17715
                     /locus_tag="JOX41_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAY6449235.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(17801..19024)
                     /locus_tag="JOX41_001485"
     CDS             complement(17801..19024)
                     /locus_tag="JOX41_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronyl hydrolase"
                     /protein_id="HAY6449236.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(19018..20916)
                     /locus_tag="JOX41_001486"
     CDS             complement(19018..20916)
                     /locus_tag="JOX41_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HAY6449237.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            complement(20910..22028)
                     /locus_tag="JOX41_001487"
     CDS             complement(20910..22028)
                     /locus_tag="JOX41_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HAY6449238.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(22111..22944)
                     /locus_tag="JOX41_001488"
     CDS             complement(22111..22944)
                     /locus_tag="JOX41_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAY6449239.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVSATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(22937..23854)
                     /locus_tag="JOX41_001489"
     CDS             complement(22937..23854)
                     /locus_tag="JOX41_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAY6449240.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(24081..25205)
                     /locus_tag="JOX41_001490"
     CDS             complement(24081..25205)
                     /locus_tag="JOX41_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAY6449241.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            25388..26296
                     /locus_tag="JOX41_001491"
     CDS             25388..26296
                     /locus_tag="JOX41_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAY6449242.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            26437..28050
                     /locus_tag="JOX41_001492"
     CDS             26437..28050
                     /locus_tag="JOX41_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HAY6449243.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
BASE COUNT         8891 a         5621 c         4868 g         9221 t
ORIGIN      
        1 ttctatttat ctatctaaca tatcctttat tcttctactt ttctttcttt agcatataag
       61 agatacgcat agtaatcaag caaggattgt tgatataaaa agaacaaata ccgctatttt
      121 gatttctttt gactctatta ctcatataaa taaaatttat tatacctgct ctttttgact
      181 atatcctcat ctgactccta tacttcgttt gtattaaaac ttaggaggaa tcattcatgc
      241 ttacagggct aaacttatta aataatcctt ttctaaataa aggaacagct tttacaaaag
      301 aagaacgggc aaaatacgga atcactggta tgcttccaag tactgtccaa acattggaac
      361 aacaatctgt ccaagcttac ggtcaatact taagcaaaca gaccgatttg gaaaaacgta
      421 tcttcttaat gaatctattc aatacgaacc ggacattgtt ttataaattg atgggcgaac
      481 atttagttga attcatgcct gtcgtttatg atcctgtcgt tgcggattca atcgaacaat
      541 acaacgaaat tttcttgaaa ccacaagatg ctgtatttct ttcaatcgac gaaccagaaa
      601 atatcaaagc aagtttgaaa aacgcagcag atggacgcga cattcgtttg atcgttgtga
      661 cagatgcaga aggaatctta ggtatgggtg actggggtgt gaacggtgtt gacatcgcta
      721 tcggtaaatt gatggtctac actgccgcgg ctggtatcaa tcctgcacaa gtcttgcctg
      781 tatcaatcga cgctggtact aataacgaag aattattgaa taatccatta tacttaggga
      841 atcgtcatgc tcgtgtagaa ggcgaaactt actacgaatt cattgatcaa ttcgttcaat
      901 cagctactga attattccca gaattgttat tacattggga agattttgga cgaggaaatg
      961 ctgcaacgat cttagaaaaa tacgaagata aaatcactac tttcaatgat gatatccaag
     1021 gcacaggaat cgttgtacta gctggtgtat taggtggatt gaatatatca ggtgagcaat
     1081 tgaaagatca aacgatcttg acatttggtg ctggtactgc tggtgtaggt atcgcaaaca
     1141 tccttttaga tgaaatgatc cgtcaaggtg tacctgaaga agaagcacgc caacatttct
     1201 atcaagtaga taaacagggt ttattgtttg aagatacaaa aggattgact cctggtcaaa
     1261 tcccattcgc tcgtaaacgc tcagaattca ctaatgctga tgaattgaca aacttagaag
     1321 cagttgtaaa agcaatccat ccaacgatca tgatcggtac ttctacccaa cctggagcat
     1381 tcactgaaga aatcgtgaaa gaaatggcgg ctcatacccc acgtccaatc atcatgcctt
     1441 tgtctaatcc aacaaaattg gcagaagcaa aagcaaaaga tttgattgaa tggacggacg
     1501 gaaaagcttt agttggaaca ggtatccctg ctgctgatgt ggaatataac ggtgtaactt
     1561 accaaatcgg tcaagcaaat aatgcgttga tgtacccagg tttagggctt ggtttgattg
     1621 cttcaacagc tacacgagta aatgctgaaa tcatttctca agctagtcga gcattaggcg
     1681 gaatcgttga tgtaacaaaa ccaggagcag ctatcttgcc tccagtagca aaaatcactg
     1741 aattctctca aacgattgct gaaactgtcg caaaatcagt tgttgcacaa aaattgaatc
     1801 gtgaagaaat cacggatatc aaagaagctg ttgaatctgc taaatgggtt cctgaatata
     1861 aatctttaga agattaagat tgttatagta aaagaacata cagaaacttt gtatgacgtc
     1921 taaaaagaaa aaagcgactg cggcaaaaca gcagccagcc aactactgct cttttgccgc
     1981 ttctctttgg cttttttcat acgatacaga ataagaaagg atctgtaaaa atggcacaaa
     2041 aaacaacaac cgcaactgca gttgaggaaa agaaaaaaga agggttttgg tcaacaaaaa
     2101 ttaccggcgt aagtttgccc ctttatttga tcatggtcct tgtcctgatc attgcaatgg
     2161 ctttaggaaa attaccgacg aatatgattg gcccaatcgc tgttttggtc attttcggta
     2221 atttatttca ttttatcgga acaaaaatcc ctatagtcaa aagttattta ggtggtggct
     2281 ccgtttttgc gatctttgcc tctgccgcga ttgctacatt tgggatctta cctgagtatg
     2341 tagtaaaatc cacagaaaac tttgtcagca atatgggctt tttagacttt tatattgctg
     2401 ccttgattac tggtagcatc cttggtatga accgtaatct attgatgaaa gcttctgttc
     2461 gttttattcc cgttgcactt atttcaatgg tcgtctcctt ttttgccgta ggactcgtag
     2521 gtatgcttat cggaaatggt tttgcaaatt ccgttttata tatctcattg cccgcaatgg
     2581 ctggtggtgt tggagccgga gctgtacctt tatcaacgat ttatgcaaat gttttaggta
     2641 cggacgcttc ttctatcatt tcccgcctga ttcctgcgac agcaatgaca aatgtcctag
     2701 ctatcattgg tgcagcgtta gttgctcgtg cgggacaatc aatgccaaaa ttcaacggta
     2761 atggtaaatt aatggaaaaa ggcgaccttg gcgatggaaa acctagaaat gtaaaacctt
     2821 ccattccaca attaggtgtc ggtttgatgg tatcattgac tttcttcatc ttaggacaaa
     2881 tctgtaacta ttttgttcct aaagtccatg cttacgcatt catgatcatt atcgttgtta
     2941 tctgtaaaat cgcaaaccta ttaccagaat attacgaaga tgcagctatc atgttcaaca
     3001 acttgattgt caaaaacttg acagcagctg ttcttgccgg tatcggtatt gcgttattga
     3061 atctaaatgt attggcttct gctttgacat ggcaatttgt tgtcttatgt ttgacaagtg
     3121 ttatcgcgat ttcagtagtt tcaggatttg tcggtcgttt gtttggttta tatccaatcg
     3181 aatcaactat tactgctggc ttatgcaaca actcgatggg tggtacagga aatgtagctg
     3241 tcttatctgc agctaatcgg atggaactta ttgcttttgc tcaaatgggc aatcggcttg
     3301 gtggtgccat cgttttgatc atctcaggtt tcttgatgca attactttct tagtcaaaaa
     3361 aaatacctga tcatcaagta tcggcttgat gaccaggtat tttttgataa aaatttacag
     3421 gattttcaaa aatctttttt gcattttatc ggaatgataa ccgatgcgtt cataaaatcg
     3481 gtgtgcttct actctgtatt ctgcagaatt aagtcttatt gctgatattc ctcgtctttt
     3541 cgcttcttct acgccagtca tcaaggcctt tccgattcct cttttttcag catgtttaga
     3601 cacagcaagt gccataatat tgaacatcgg atcgctgaaa atcgattcat aggactccgc
     3661 ttgtacatag ccagctgctt ttttagaagt aggatcttca tagaccaaga aaaaattttt
     3721 ttctggctcc ttcaacagtt tcttcatttg tctcaccgta acggttaatg gtacatcata
     3781 tcctaattgt tccgcattga tttctcgtag tgcttctgca tctcctaaac gcatttcccg
     3841 caacatccaa atcaccagcc aatttttatt tttttaaatg aattttttta tcacagtata
     3901 ctcctttttt cacttaaaaa aagacttttc agtgattttg acttgcttga atccagatcc
     3961 ttctaatgtt tgcaagatga cgaaagcatt gtaaagattg atcaaaagaa ccacgatgac
     4021 aatcgcttga aaaataaagg tcactttttt tggagacaaa accctgctaa atcttgctcc
     4081 ccacaaacct ccaataacag cagcggggat aacataaaac aacatagata aatcaaagcg
     4141 cataaagcta cttgttaaag caatcgttac caattttgcc agttgagaaa agaaaatcgt
     4201 agatagagaa tatagtgttg cttcttttat tggcaatgca aacatcagca tcaacaaaga
     4261 aacattgact ggtccaccac caatacctaa aaaactagct aaaaagccca gaaccccccc
     4321 acatataagg taccaagtcc atgacgtcaa atgaaatttt ggctgatgat gcttggtgta
     4381 gaagaacgca aaaaccaagg tcaataccgt caaaaaaatt tggatcagct gcacatgctt
     4441 ctcgttttca aataactgta aaaaaacttc gaatacaatg ttgccgacta ctcctccaac
     4501 aacagctcca ctagataccc aaccgacaat ctgccaattc agtgatttcc cgcttgatac
     4561 ttgtcgcaca gtcgaaacaa tggacatcgt gaataccgca actgttgagt aaaaagaaat
     4621 ccctgcaaca gaatgggcgc cgataagatc aagaatcggt ttgatcaaca cgcctccacc
     4681 catcccggaa atagcgccaa ctgtgttcgc cagaacgatc accacaaaat aaatcagacc
     4741 aatcatcttg tatttccttt ctcttgttta tatcttttag cgattgttac tcttttcttt
     4801 tattatacag taaaagaaac aaacgaggct tcgaaagctt ttctactttt taaggaaatt
     4861 tagtgctaaa cgaaaaaacc gggctctact tttcagagag tccagctttt cttacacctt
     4921 atcgattctt ttgttctatt cttcttccgc catgaatgta ttgaatactt cttcgatcat
     4981 atcccattct gcgtctgttt cgatttgttc taactcgcct tctgttccat cttcgttttc
     5041 gatgtatgca taagcttgta attctacatc ttcatcttct gaaacaccag ctggatataa
     5101 aagaacatag ttacgtccaa attcttcttg tccgtcaact gttagcaaga tttcgtataa
     5161 tgtttcattt ccttggtcat ccaccaatgt gatgtgttcg tgtccttcgt gttcgtggga
     5221 atggttatgt tctgtcataa gattacctct tttcttttta ttattaaaat aattgcttac
     5281 ctgagccgtc taaataattt tgtaaaatca tcacagctgc taatttatcg atgacttttt
     5341 ttcgtttcgc tcttgaagta tttgcctgct ctactagcat acgttctgcc tgaacagtgg
     5401 ttagtcgttc atcttgataa tcaaccggca aggagaatag ttctttgatc ttctctccat
     5461 atgacatgga agcttctgcc cttggtccga tggaattgtt catattctta ggtaatccaa
     5521 ctacaaaacg gtctacttcg tactgcgcca ctaattcctt caaccgatca aaaccaaact
     5581 cttcttctgc ctcattgatt cgaatgattt ctactccttg agctgtccag ccaaagggat
     5641 cgctcacagc aacgcctact gtcttagaac cgacatccaa gcccattact ctcataaatt
     5701 cactccatga tttgagaggt agtctttgac aattacttcc atgatttcat cgcgttcgtg
     5761 acggcgaatc aaatttcgtg catcacgata acgaggaatg taggccgggt ctccagaaag
     5821 caagtagccg acaatctgat tgattggatt gtagcctttt tcttccaaag cccgataaac
     5881 aatcgctaat gtttcgctca cttctttttt gcgactatcg tcaaaaccaa aacgtacggt
     5941 ttcatctgta aaacccatga ttctacacct ctttcccgca aggtaattcc agcttacctt
     6001 ctacaccctt attttactcg aagaaaggga aaactacaaa caaatattcc aaacttctga
     6061 ataaattaag aaacacgatt tgtctgattt ttcctttttt ctgtggcttt ttcaaaagcc
     6121 ctctttccat aaagtatacg ctatatttct ttgaaagtat gtttttacac aattttttca
     6181 taaagttcat aaaaaattcg aattgctgct actaattttt cgttttcgtt gcttgccctg
     6241 tctcataatt gatggtgtag ccatcttgaa cattgtagat aaagacattg aattcaattt
     6301 ttttgtcttc aatgctttct gcttccaact gcacacctct tgctaccagt tcatttccct
     6361 cgaaatgagg agtgacacga tagcgtacat gatgatttgt ttccttgata tatgccgcaa
     6421 tatcattttc gtgggcaagc atgtacggag cattcaacga acgtgtccct gtcattaagt
     6481 ttttaatgtt attattttga ccagtcaact ggaaaccaat caaatggctg cggttgtata
     6541 accattgtcc gtcacttaat ttcttttgtt tccaacctgt cggatcaata tacaaaggtt
     6601 ctctcttttc agtaggaaac aagtcttttc ccaacatcgc attggcttgt cctactctgt
     6661 tcaatttgtc tatatttgaa tagctttccc atgtcccttt ggaaagacta agatcctctt
     6721 ttgtaaactc cggctgattc ccattgattt ctatttcttg atgttttcca tcatattctg
     6781 gcacatccgc tacttgagaa gcttgcggtg tggaatcaaa aatggttgta atttgttgga
     6841 agatatctga atctttttgt gtggtggaaa taccgagtgc ccctgcaatc acagcagcga
     6901 cgatccccac gatcgccttg gttgtttttt tgctcatttc tttactcctt tactaacagt
     6961 tccctaaatc ttaacatatg ttcccctata aataaatact ggaaagaaat agaaacagta
     7021 aaaaaataaa accagttttt agacggctta agaatacaaa aaaagagacg gattcatcgt
     7081 ctctactcaa tcacaaaaca ctatttacaa ggtatttatt atcattcaaa aaatttttct
     7141 taatactcaa aactaaacgg cttctgtacg acctcttggt aaacagtgtt caaaagcttg
     7201 catctgcggt aataagtcca accaagtcaa aaacataaga agcttttttg cttgactatt
     7261 cttattactt gatgcagggc agctttttca cagcctcttt taagcgggtg acgggaatcg
     7321 aacccgcgac atcagcttgg gaagctggga ttttaccact aaactacacc cgcgatacaa
     7381 aaacagtata cgcctctttc actccttcct caagtttttt tattctttac gcttccgata
     7441 tgttttgtag taaaataaaa ctaatcaatc aattattgga gaagatgcta tgacgggaaa
     7501 agaattagat ctgttgctgg acacttgttt actcgctggg aaaatcatga tggaaagcaa
     7561 tgcggagatg tatcgggtag aagatacgat gagtcgaatt gctttagctt ctggaaattt
     7621 ccgtttggtc agctatgtca ctcaaaccgg tctctttatt ggtcttgatc gtacctcgac
     7681 catccgaatg gaacaaatta ccaaccgttc gattaattta gaaaaagtag taaaagtaaa
     7741 tgatctttca cgtaaatatg ttgcttcaga gctaacatta gaagaacttt actgcgaact
     7801 gcaagcaatc gaccgagacc gttctttctt tcctgtctgg ttgcaaatcg ttagcgcggc
     7861 agtgatcagt ggaacaatta tggtgttatt tggcggaaag atgaccgatt tacctgtgac
     7921 tttagtcatt ggaggattgg gatacgcagc ttatctatat agtttgaaat tttttagaat
     7981 caaattttta tcggaatttt tatcttcttt attgattggc atagccgcta tctacagcgt
     8041 acgttttggc ttaggaagca atcaggatct aatcattatc ggatgtgtga tgcctttagt
     8101 tcctggagtt caaattacga acgctatccg tgatttgcta gctggacatt atgtctcagg
     8161 agtttctcgc ggaacagaag cgatgatgac tgctacgatg atcggttttg cgattgcttt
     8221 tattttccag cttttttatt aggaaaggaa cacaagtatg gggacgatat ttattcagtt
     8281 ttcttttagt tttttagcga ctgcggcatt tgccgttatt acaaatgtac ctaggcgttc
     8341 attgatttgt tgtggtcttt ctggtgcttt tggctggatg atctactgga tctgtgttca
     8401 aataggcgga tctgctgctt ttggttcatt gcttggttct ttaggagtag cattcatcag
     8461 cgatcttttc tctaaacgtt tgaaaatgcc cgtaacgatt ttcaatattc ccgggatggt
     8521 tcctctagtc cctggtggtt tagcttatca agcggttcga aatctcgtta ctgaatccta
     8581 tcgagaagcg gctcattatg cggtccaagc aattatgatt gctggagcaa tcgctttagg
     8641 tcttgtatta tcagaagtct ttaaccataa catccgtaat ttcaaagtaa agcgtgacgc
     8701 aatcatgatg aaacgaaaaa aacggctttt taaataaacg aagtgtaaca aagaaaaggt
     8761 tgtgaaagag acgttcagcc ttgagcgatg acaaaatatc tcacaaacat tgcgacaagt
     8821 aaccgcagga gcaataagaa gtaattatga gtattaaaaa aagttttgta aaaatagctt
     8881 ctcacatttt tacataaaat tgacttaata ctgagaaact gacttttgaa caccctctat
     8941 ctgtaaaaaa ggggctgcga catgattttt gtcacggccc ctcttcttta ttcaaatttt
     9001 ttccaaaacg ttcgttgata ataaacgatc catagagcgg aaagtattag aactaaaccg
     9061 atcacaggaa tattcactaa ccaaaatgga taaaacaaag ccaacattcc gtataagacg
     9121 ataagaataa tactgatgat caatgaaccc atcatagttg cgactaaacc caaacttcct
     9181 gaacctctgt taaataattg gttaatattg gtccagttca gcagcagcaa ccgataatct
     9241 ctagcgaaat aacgtagtga caataagtag cagccgaata aagaaccaaa tagcaagcta
     9301 gggataaaaa acaaaggcag ctgaaaagac agtccgctta ataatgcgat cccaccagtt
     9361 aaaaaactct gcaatatcca tccgaatctg aacttttctt ttaaatattg gttcatagag
     9421 attggcaaag aacggataaa cagaaaattt tcttgatcca aagaaataag attgctgata
     9481 aaagaagtct gattaactgt taagaaagcc aatgcgatcc ctaccaggaa aacaacaccg
     9541 attaacttat tatctaaatc agttaatttt atttcgcctc ctagggcaaa agcaagaata
     9601 aaaatgattg gagttaacaa ggaagaagaa agaacttgca taatcaaatt aggttctttt
     9661 actaattgag cattgtaact aaataaaagc tgatgcacat tttggttctt tttatgggtt
     9721 ctttttattt tgaactcact gtttgaatca gtcagttgct ctgtaagctt tggtactatc
     9781 agctgtttta cagcaaggaa aaatcccaga gccgtgatag ctagtattcc ccaacccaat
     9841 aaaccttgtt gagaaagtgg ctgactggca gcatcataga atggcaataa tatcgaaatc
     9901 ggatgccgat ctgttaactc attttcaata gtccccgttt gatgattcat ccacatgatt
     9961 ccagcaaatg cgatcagcat cgagctgcca agcaagatac tagaaactgt ttttctatgt
    10021 tttttaaaca ctgctgttcg agccaaacca aaaacaatca aactagccag acaaaaaaga
    10081 ataatcaaaa atagagaaaa caaaaggatt gagataatga tagtaagcaa aatccctaga
    10141 tcagctcgcc atccggttaa aataaacatg actagaagcg gaaaaacaaa aggaatgatg
    10201 gtcaaagcaa ctaccaaaat ctttgctgaa aaaacctgtt cttgtccaaa aggcagaggc
    10261 aaaaatactt gcaggtcatt tccttcaaaa aagatattat aaatgactga tatactttga
    10321 gttaaaccta acataccaaa aagtgccacg taataagtaa agaaacctgg caatttaaca
    10381 aagttcatag caaacatagc aaatccgtaa atcagtaaaa aaatcagccc tgaaaaaaga
    10441 ttttgagaca aaagatagat agttaatcgc tttccctttt ttcctttctc tcttgcttta
    10501 ttcgtgagct gtggattaac atataaaaga ttaactcgaa ttaattctaa taattgtcgc
    10561 ttatacatac ggtccatctc ctgtcgcttg ccttccagcc attttcaaat aaatcttttc
    10621 tagcgtttca tcaggtgagc cattcaataa ttcactaact gccccctgat aaatcaattc
    10681 acctttcttc aaaatagcca gtttatcgca taactgttgt gcggtatcca atacatgtgt
    10741 agaaaaaatg actgtttttc cttttgcggc atgagccttc atcatttctt tcaaatcaaa
    10801 tgctgcttga ggatcaagtc cttgcaaagg ttcatccaat acccaaatat ctggatctgg
    10861 cagcaacgtg ccgatcaaaa tcgttttttg acgcattcca tgtgaaaaac ttgcgattgt
    10921 ttcattttga tgactataca tatcaaaaag cgctgtcaat tctgctaaac gcttttcttt
    10981 tttttgtgtg tctaattcat aggcagctga aatcaagtcc caatattctc cagccgtcaa
    11041 ttgtaaaaaa atatctgggg aatcaggcac ataaccgatt ttttgtttga tactcaatcg
    11101 attttccgtc aatttcattc catctactaa aatcgttccc gatgatggtt caataatact
    11161 aactaaactt ttaatcgtag ttgattttcc ggcaccatta tgtcctaaaa atccaaaaat
    11221 ttccccttgt cttatcgaga gagacaagtc ttttaatgct tgttttttcc cgtaactttt
    11281 acttacattg atgaattcaa tcatttctgt actccttttg tttgttatta ctttttattg
    11341 tacccttcgt tattggtgga gtaaatgtca aaaagagtgc ataacaaaaa aggatagaaa
    11401 cgactaggct gctacttggg ttgttctctt ctacaggaaa acactcttct aacaggtaag
    11461 atatgagtct ttgttttctt taaaatgatt cattttctat cttttcttgc ataaaattct
    11521 ttagtttatc aatacttctc tttcccatct ctagttgttc tccatttgca aatgttacta
    11581 tttcgtttac tctgctaata gatgtaatgt tttcagtatt aatgatataa gcttttaaat
    11641 ctttacataa atactcatat tcgagtgatt ttttatattt tttaattgtg ccgtttacga
    11701 gaatctcttc atctttcaat actaggccta ttttattttt ataacctggc atgctcatta
    11761 gataaaggat ttcatcgtaa tggatatagt gatcgctatt accataacgg acagttgtcc
    11821 accttttttt cgtagcatgt tgaacaggat agttttcttt ttctttcaat aagtaacttt
    11881 ggatgctttt tttatttttt tcataagtga attcttttat caaataacca ctaggcgtaa
    11941 tctttcgatt aataacagtt attgctttat tcggatgaga cgttagataa acaattttac
    12001 acttttcatt cttttctcta agcatttcgc ctagttcgat accgctataa taggcgttca
    12061 aatcgatgtc taggaaaaaa atatctgagg aatagatttc attattttta atgaattcaa
    12121 caaattgtat aacgttcaat ccctgaacga tctcaaattt ccaaggactt aataaaattc
    12181 tggattcttc caaaatttct actagcattt tttcaaaaac caaactatca tccaaaataa
    12241 atatacgcgt taccataaaa agtacctcca ctcgatattt tactatcaaa atcatttcat
    12301 acaacttttc aacatacatg ttaggaataa attgtaattc tcttcacaat cttttccaac
    12361 acctttgaaa ccgatatcaa atactttcag gatgctgctt ctaaaataaa tatcaaacaa
    12421 atgaatacat catgcaaaaa aagccagaca accgacgtcc ttgcgtgtca gctgtctgag
    12481 ctatgtttat ttattttgtt cttttaaaaa gaacgataca catactgatt tttcggagca
    12541 gagactttct cagcgtttgt aacaactaca gatgggattt cacgcttgaa tggttgataa
    12601 tagtctgatt ggatggttcc ttctatttta taccattcat catttttaac cgttactcct
    12661 tccggcatat gcgtcaacaa accaaagact cctgaatctg ccacacaatg gataatgccg
    12721 aatcggaaca agaagatatc tgtattgcta tcgttcggtg tttggtaaac aaatccttca
    12781 tagctgattt ttttgccaat gaattcgcta gggtaattat aaattagctc cataacttct
    12841 aaatagtttt catctgtgat cttgatagtt tgcttatccc catacttttc tttcaactca
    12901 ttcatttggt ctaagtagtc tgatttgttg aaataaatac tggtatccgg ctttaagtat
    12961 tgtgtctgca tctccggatc ccctactgat tctttactta ctgggaaatt aaatcctttg
    13021 gcttctacga tcgtagtgtc gagactaact gttggaaaca acgtccccac gattactggc
    13081 aaagctagca gtacataagc gattccacgt tgataaggtt ttgacaaccc atggtcatga
    13141 tcgtgctcgt gtgccttttc ttctgctttt ccgtttttga cccacaaata cagctgaact
    13201 aaagccaaaa gagcagataa aatcattgaa agaatagcta agtagcgata atggacattg
    13261 atatattgat cgagtttgcc agaaacttgc aagtacatca tcaattcgaa atacccagat
    13321 aaaatcaaaa accgcagcat attttccctc ctaaataaat aatgtgaatc caataacgct
    13381 aagggcaatc agtccgatca gcgataaaat aaagcgtcct gtaaaatatc gtttcatcat
    13441 cagtagattt ttgatatcga ccattgggcc aaagaccaaa aaggcagcta caggtgctgt
    13501 gccgaacaga cttaacaaag aagatcctat aaacgcatct gcttctgagc aaagagacat
    13561 cgtaaaggcc aataacagca tgatgataat ggctaaaatc tttgttgagc cgagcgttag
    13621 cataattcta gttggtaaat aagtctgcat cgcagctgcg attaatccgc caatgatcaa
    13681 ataacgacct gtatcaaaaa attcgtcgat tgaatgtgtc aacacatgcc cagtttgatg
    13741 gatcagctga ttttttggtt cattcttctc actttgttct tcttcatgga catgatgatg
    13801 gtgattttct gctactttag acgtgatttt ttctttcaat acagcgtctt tttgaaaata
    13861 ggcaagccag acaccaatca caagggcaac aaaaaagctg cctatcaccc gccagcttgc
    13921 catctgccaa gaattgccaa atgcgataaa agtggaaaaa atcacgattg gattgatgat
    13981 cggagcagtc agcataaaag caaacgctgt gtgaactggt acgccttttt taacaaattg
    14041 atgaacgatc ggtacgatgc cgcattcaca tgaaggaaag aaaaatccta agatcgaacc
    14101 agtaaaaata gagaagatac gattttcagg aagccatctc ttcacacgtt ctggggtcaa
    14161 aaatacttgt aaggcgcctg agataagaca gcctaataat acgaaaggta atgcttcaat
    14221 aacgatcgat aagaaaatcg tactcatctg caaaaccgaa tttggaataa aagaaaacat
    14281 gagtttcctc ctttttattt ctagttcatt cgctttgcaa atatacgctt ttattcaaaa
    14341 aaaacaagtt gctctgtaaa tttttacaca actcttattt tttaccaaag cacttcaatt
    14401 gactttttct gttattccca ttaaattaag gtctcataca tatcacttct atcataaaag
    14461 ggagaataaa aatgaaacaa accactaact tgactgaagt tcaagacata ctgcaacagt
    14521 catccgttgc cgtcatttat ctttcgatgc ctaattgcag tgtttgtcac gctgttcgtc
    14581 cacgactaga ggaacttctc acacattatg atattccggc acttcatttg gatgcatttg
    14641 aaacaccaga agtagctagt aaatttgaag tgctgactgc gccagttgtc ctgatttttc
    14701 atcaaggaaa agaagtcttt cggcaagcac ggttcatcga ctttaaaaaa atccgttatc
    14761 tactagatga actgacagca gaagatgatt ccctttctta tgaagaaatc ttccgaacaa
    14821 aataatcgtt gtccaaacag aaaaaagcga ttgaacaagt gaaagttttg ccttcatttg
    14881 ttcaatcgct ttttattttt attctgctgt attttcggaa tgcgcatttg cgtcagaatg
    14941 caagaaatag atcaaggttt gcaattcatt cgtcaaatca acattttgga tcaatacatc
    15001 tgacggagca ttcaatcgag cagcggtaaa gttcaagatt cctttgattc ctgcttccgt
    15061 taactgattg actacttctt gtgctctttc agcgggtatc gttaaaattg ctacttcgat
    15121 ttgttggatc ttgatttgtt ctgacatatc ttccattgga taaacgggga taccgtctac
    15181 gatgcgccca acgatttcct cattcacatc aaaagcacaa ctgatacgta tgctattact
    15241 ttgatggaat ttgtatttta gtaaagcact tcccaagttc cctacaccga tcagcgcaac
    15301 atttgtcaat tgatcgtcgt ttaatgtctt tgcaaaaaag tgcataagat cttctacatc
    15361 ataaccatac ccacgttttc ctaattcgcc aaaataagaa aaatctcgac ggatcgttgc
    15421 actatctact tgaacggctt cacttaattc agttgaagac acttttttct ttccagcatt
    15481 atttaaaatc cttaaatagc gataatacaa aggcagtctt ttagctgtcg cctttggaat
    15541 aatatgatct ttcacgaaat gacctccacg tattgtctaa ttacatcttt gatttctcca
    15601 tcatagcagt atttatagga aaaaatcaat tccattgctc agatattgtg aaattttatt
    15661 ctttattcat ttatttatca tttctgcaaa tctcgcagta taatggaatt tatggtagac
    15721 tactaattga aaaatagttt tttatttgag gagaattcac aaagtagaaa agaggattcc
    15781 atgatattat tacaagccaa tcagattgct cgccattttg gtgcagaagt cttatttgaa
    15841 aacatacatt tagaaatcag tacaggcgct cgtgtcgctt tagttggcag aaatggcgct
    15901 ggaaaatcga ctttattaaa gatcattgct ggaattgaag cacctgatga aggaaagatc
    15961 gctaaaaata aaacagcgac tctcggatac ctcgctcagg acacaggact tgattccaat
    16021 gaaacagttt ggaacgagat gctgaaagct tttgaacaag ttagacaaat ggaagagcgg
    16081 atgcgcgagc tagagatttt cattagcgaa ggtacgccag acacacctgc ttatagttct
    16141 tatttaaaag aatacgaccg gctgcaacac gatttttcag atcgaaacgg ctatggttat
    16201 gaaaatgaaa ttcgttccgt attgcatggg tttaaattcg attcttcatt ttatgatcag
    16261 aaaatcgata ctttatcagg cggacagcgc acacgtttag ctttagctcg catgcttttg
    16321 caacaccctg acattttgat tctagacgaa ccaacgaacc atttagatat cgagacactt
    16381 tcctggcttg agaattatct gcaaagctat actggtgcat tattgattgt ttcccatgac
    16441 cgttattttt tagataaagt agtcaatgaa gtctatgaat taagcagaag aaaaatgcgc
    16501 cattacaaag gtaactattc gaaatatcta gatttgaaag cagaacagtt agcaagtgaa
    16561 tggaaggctt atgaaaagca gcaaacagaa atccataaat tagaagactt cgttgctcgg
    16621 aaccttgttc gcgcctctac cacaaaacga gcgcaaagcc gcagaaagac attagaaaaa
    16681 atggaccggc tggatcgtcc tcaaggggat gaaaaacaag caaactttct attcagtata
    16741 gaaaagcctt ctggaaatgt agtcttgcaa atcgaagatg ccgctatcgg atatgataat
    16801 gtcaccttat ctgaaccaat caatctagat atccgtcgtc aagaagcgat tgctctagta
    16861 ggtccgaatg gtatcgggaa atcgacgttg ctgaaatcaa tcattcacca gatccctttt
    16921 atccgtggaa aagaaacgct agggacaaat gtcaccatcg gctattacga tcaaggtcaa
    16981 gctgatctgc atacaaacaa gacgatccta gcagaattgt gggatgagca tcctaccact
    17041 ccagaaaaag agatccgaag tgctttaggt gctttcttat tttctggcga agatgtagaa
    17101 aaaccaatcc ctctgctaag tggcggtgaa aaagcacggg ttgctttagc caagttagcg
    17161 atgaacaaag aaaatttttt gattttggat gaaccaacaa accatttaga tattgacaac
    17221 aaagaagtat tagaaaatgc attgatcgat tatgacggca cactgctttt tgtttcccat
    17281 gaccgatatt tcatcaatcg gatcgcgaca aaagtcgtcg aactctctga aaatggcagc
    17341 aaagtctatc taggagacta tgattattat ttagagaaaa agcaggaaga agaagaaatc
    17401 gccgaattgt tggcacaaga tgagccagaa tctgctcctg ctcccacgaa caaatctgat
    17461 tattaccaaa gcaaagaaca gcaaaagctt atccgtagcc ttcaacgaaa aattactcag
    17521 gttgaagaag aaatggcgcg gatcgatgaa tggatcgatc agttggaaca agaaatggtc
    17581 gcgccagaaa acctggaaga tcacgtaaaa ctcaatgagc tgaaccaaga tttagaagct
    17641 gctagacaag atcaagaaac aaaattgacg gaatgggaag aactaagctt ggaattagaa
    17701 gaatatgaaa attaacgaaa aaaccaaaac agaaaccatt catgctgttt tggtttttct
    17761 ttttttattt tatcaaacaa aaattccata tttacctttt tcaccaataa gaagaccaat
    17821 tactagtcat tctcactaaa gcttctaaat aatagtaatc accccaaata caaggtgtat
    17881 ttaccccatt atttttgggc ttattataaa cagactgtgt taaaaagcca tcttcttctt
    17941 ccgttgtagc atatctttct ttcaattgtc gcataatttt ccaaacagca gactggtata
    18001 agttcttttc tgttttgtct aatagacctg attctattaa ttctaataat ccacaaacca
    18061 tgatcaccat actagatgta tctttttctt ctctgctaga atcatcaaag atcaaatccc
    18121 aataacaaat ggtatcttct ggcaaccgat tcataaaata attggctaat attttgctta
    18181 aatcaaaata tttttgttct ttcaaataac gataacttaa tgcaaaaccg taaatccccc
    18241 atgcttggcc tctagcccaa caggaattat cactataacc ttgatgcgta cttccatatc
    18301 ttggttttcc atctttgaca tccatataaa atgtatgata agttgaacca tcttctctta
    18361 ctaaataatc tgctgcattt tgaatatgag cctgagcagc ttttttatat ttttgatttc
    18421 cagtttcttc actcgcccaa tacaataatg gaagattcat gcaacaatcc atgatcattc
    18481 taccttgttg tgaaggatca ctaggatctc cccaagcttg tataactcct gccttctccc
    18541 aaaaacgctg aagtaatgtt tctgcagcat caattgaagc ttccttcatt tttcgatttc
    18601 ccgttatttt ataatctgct acggttgata aagaatacaa aaaaccaaga tcgtgatgat
    18661 tagtgataat ttgacagtca atcctgtgga taaaatctat atctgctttt tcagctgttt
    18721 gttgaaataa aggatcaccc gtcttctcaa ataacaacca attaattcct gtccaaaatc
    18781 cttctgtcca accaatattg tctcttaatg gataacgtcc ttttatagga cactcgcttg
    18841 ggaattgata ctgactgtta ctgatacgtt tgattaacct ctccgtgtgt ctgcgacaac
    18901 gctcgatctc attattccat tctttttcca ttaattcttt ataacattca tttatccatt
    18961 tttctggatg tattatctct tcaaacatca ctttatcaag catttcccca ccagccttta
    19021 gcataatttt agtctttttt tattgttttt attttggata gttagcccgg ttgtcccatc
    19081 aaaatcaatt ttgggacgat tgttccatac ttctaaacta taatcccgat cttgatgagc
    19141 aaccactcct gttccgagcc aatgggttcc ttttccaaat gtaccctcta atccaggaat
    19201 aaaagtgttt tcccatgtca tcaagtttgt attgggcaaa cccataatag ctgtggattt
    19261 tcgtttaata gtatcgtcac ttaaacagat aatacctgaa aagccagctt cactcaccct
    19321 atagttttcc ttgtcttctt ctatgattat tccttctttc tcaggagaac attcaatagc
    19381 aaaccctgtc tcatatagaa catattctgt atctaattct actttgtgta cgcgaatctg
    19441 ccagccttca aaaggaataa gccaagttct gatttttgcc tgtaaagtag gttcccatgt
    19501 agaggcaagt acctctttct tacatacaat gtctcgtaca ttatttcgaa cgatgaactg
    19561 tccataggtt ttgatgctct cattcttaaa actggtcgtg atatatgtgt ccgctcgctg
    19621 aatccctagc attgaatcca ttgccatttc tgctttcaat tgattcgctc gcggtatcga
    19681 aaaaccaaat tgactagaat aagcaaattt taaatatttt tcattggtca atgtatggaa
    19741 atttggccct aattgtcccg cattcaaaaa aaatgtatgt ccattatcat gttgtatgag
    19801 caaattggct tctgaaagaa gtttagttcc ttcacgaata ggcataggca tttctttagc
    19861 cgtccaatac tcatggtctt caggtagcgc caacaataaa aaaatcttat tcagccataa
    19921 tggagataac gtactattat agggttcagt caatgtcaat tgagggtagg tataaccaat
    19981 attcaggata cctttttcat caaatatttc tttttgcatc caccatctta tattccgatt
    20041 gactaacccc ttgatttcac ctaatttaaa aggcaaaaga tcggcccaca acatagctga
    20101 ccaaaagctt gaaactgcaa aacgataaat catgcttcga ccaaaaggca catttgcacc
    20161 atcttccgca aaaaaatgaa tatagtctct agaaaaatca atagctcggt tcttatatat
    20221 ctggctaatg ggcttttctg gttctagtac gctataaatc aaaccataat aatgaaatgc
    20281 aaaaggatta taataatctt ggcgacctct tgaactgtct cgataccagc cattttgaag
    20341 ataacaattt tctatattat caaatgcttc tttcagtgct gattctttaa ctggataacc
    20401 aaatttttgg ataattgttc cgacaattat cttaaaaaat tgccaattac catctgcaca
    20461 ttcatattca aaaatttgcg agaaccaatg aataatctgg cttttttctc ctgtatctaa
    20521 ttttttccat aataattgtt catgatgata taacgctaat aacattgcgg gcatttctac
    20581 catacgctgg tctctttcat gtatttctcc ccaataatcg ggatgggaag gatctgttcc
    20641 agcttttatt cctgatagaa ttaatttcaa ccatcgttca tctaattggt caattgcggg
    20701 ccccgctccc cataaaaccc gagagaatcc ttccattcct gcaattttat ttccatatcc
    20761 taccccttga tgtatataat caatttgtgc gccacttgct cgataaaacg gctggagtgg
    20821 ttgatttatc tttttaaata agtcaaagta atcctgtctg gtccttaata gtggtactgg
    20881 atgtttcatt gtattttctc ctctttttac taccaaatag ctaattccga ctgttctaat
    20941 cgaagtaagc cttcaataaa aaaataatca gaatagatca gtggcacatt ataagtcagt
    21001 tctctatggt atgcttctgc tccgcctcca atgatcccat cttcatccat attccaattt
    21061 gcatagtgct tttctgtctt ttggagtata ttgatagcag cttcatgata catttttgat
    21121 cgtacagagg aaacatatcc tgctaattcc agaagaccgc atgcagcgca tactccagca
    21181 ctggtatcaa tattcgaatc ttttacagca aaatcaatga gaggaatata accagttttt
    21241 tcgattttct gaataaaatt tactgctatc ttttctgcta tagctagata gtacggattt
    21301 tttgtgtaac gataacttaa cgcgaatcca tataaagccc atgcatttcc tctgctccaa
    21361 caagaattct cattgtatcc ttgcccgcca agtaaccgaa tatatttccc tgattctgca
    21421 tcaaattctg cgatatgccc ggttgatcca tctttcctca ctagatactt agctgttgta
    21481 tctgcatgct gccgagcaat tttagagaac ctcggatcac cagtttccct cgaagcccaa
    21541 tacagtaatg gtaaattcat catactatca ataatcatcc aaccaggttt atggtcattc
    21601 catgctacta aatagttccc tgaaatatta tagcgtccag caagtaccgt agctgcatgt
    21661 aaccctagtt gtcgactatg tttgttttga gactgttgat aatgtgcaat agccgatggt
    21721 aagaataaaa aacctacatc atgatgaacg tctgaaaaat ggtacagggc agattctaat
    21781 aattgttctt gttgtattgc tgcctctttg aacttttctc gttttgtctt gtgaaagagc
    21841 tgccataaaa taccactcca aaaaccattg gtccaccagt cgattcctct gtcctttatt
    21901 acgtctgtat attttccgtt gtaagaaata tatggaattt tattccccat tctgtctaat
    21961 tccgcatcta tcttttcaga agctacattc aaaatttttc ttgaccattc cttcgtctgt
    22021 tcattcatgg atatcccgcc attcttttaa tttttatgaa tgtggagttg ctcctagaac
    22081 gaactagatg gttaacattc gttatttttt ttacttattt gcagctccaa tgtcattctc
    22141 cttaaattta gactgcgccc acacataaat caagaccatt gggatcactg aagttgctaa
    22201 aattagcata attgcgccat aattaattgg ctcacctgta ctagaaaccg tcatattttt
    22261 gataattaag ggaaccgtat atttatcttt atctgaaagc atgactaatg gaaatagata
    22321 ttgattccaa cttcccataa agataagtaa accactagta ataatcgtag gtgataaaat
    22381 cggtacagcg attttcgtaa aaatcaccca ctcattggca ccatcgattc tggcagcctc
    22441 catcagtgct gtaggaaatt gactgctata ttgtcgcatc ataaacactg aagttgtact
    22501 ggcaatcgaa gggatgatca cacctgcata agtattcgat aatcctaaac gactcataat
    22561 gtaaaataaa ggaatcaatg tggtaaaaaa aggcaccatc ctagatagca taactgtatt
    22621 gaacaacagt ttattcccca taaaacgata ctttgctaat gcataacccg ccattgtaga
    22681 actggctgta gctgaaactg tactgattac agcaataaca atcgaattcc aaataatcaa
    22741 gggataatta tatctcgcca tgatggcttg ccagtttttt aatagcatat ccccaaactt
    22801 gaaattgatt ccgccactta aaatttcttg attactttgc gttgaagcta caatcatata
    22861 taaatatggc atcaaaaata ttaaggcacc aaacacaata atgacgtacg taaaaattct
    22921 gctttgtatc ttttgtttag tcatttttat cacctccgaa tttaaattga atagccgata
    22981 atataacaga tacaaacacc atcgtccagg caatagcaga ggcttttcca aaatcaacca
    23041 tttcaaaact tgttttatat aaattgactc ctacgaccaa agctgaattt tctggtccat
    23101 tggaagtccc aaagaatata tttgggatat tgaaattacc caagccattg atagtggcta
    23161 aaactgtggc cattaaaatg attggcttta gcatggggat cgttaataaa aagaattgcc
    23221 gaaatttcga tgctccatct atttcagcac tttcgtatat ctctttagaa atcccttgaa
    23281 gaccagctaa aaataaaata gtgttatatc ctacactaag ccaaatcatc gtgatgatca
    23341 ttgatattcg tatccaaaaa ggatttgtta accactgtac accgttaatt cctagcgcat
    23401 tcaaaaatcc attgaataac ccagtcggat tgaaaaaagt catgaatacg gaagctacag
    23461 ccaccgttga tgtaatggtt ggaatataat agacagttct aaaaaatcct tttcctttta
    23521 actgtgctga attcaataaa acagcaaagt aaatagctaa tagcatcgtt attggaattg
    23581 atcctgccat gataatcaaa acattcgtgt aagatttaat aaacaatgga tctcggaaga
    23641 tagctagata attgtcaaat ccaacaaatt caaatgagta gccaattttc ataaaactaa
    23701 aagcaaacga gataatgatg ggaatcaaaa tcgtcacaat aaagaaaata acaaaaggtg
    23761 tgaccaatcc ataagcactt tttttatgag acgtatctgt tgcttttttc ttgctgttct
    23821 ttattgtctt gcttggtaac gaagattgca tcatcgttaa gtcctcctaa tattttttaa
    23881 tcaccagtta attttacgcc gtacttatga gcaaaatttt ctgcttcttt tagatatgaa
    23941 ttttcaaaat cacctgtttg ccaatagtta tatgcagcgg tagtcaaata agacgtagca
    24001 tctgaataag tggctggtaa aacagtattt gatgtatttt cattgatttt attcaatagt
    24061 tcatagtatt tttgtcctcc ttagtagtca aactttttct cagctgcttc tgtttgatag
    24121 gccaatgagt tagatgtagc cacgcccagc tccagtgcgt tggctaagca ttcttcatct
    24181 gtcagcataa atgtaagaaa ttgttgtgcc acttgtggat ttttggcatc tttagggaca
    24241 taaaaacttg atcctcctga tactgcacct tttcctggat tttcttttga aaaaggaatc
    24301 agtggagcca tgcgccattt gtcagatgca tcaggaaaat tcaaagacat attcgtagca
    24361 taccagccgc cagcaacaaa cattgcagat tcttgaaatg ctttctcagc atcttgtgca
    24421 ccgtagaaat gtacaatatc tgagtcgatc atttctttga ttaactttgc agcatgtttc
    24481 gcttctttag tattcagacg gatatttcct tcttcatcaa gcaaagattg attctgctgg
    24541 gctagcatgt tgataaacaa ttcttggtcc ccagattctg gcaaggcaat tccaaaacta
    24601 ccagtttttt cttttaatgc ttttgccacc tggatatatt cttcccaaga actgatttct
    24661 tcaaaatcta cacctatttc agcaaatttt tttggttgat aataacaaag tgctggggta
    24721 aaatcactag cccaaggaat aatcgtttca ttactcgttt gttgacgcaa aatattcaat
    24781 ttttgatcat aaaactgatc gccatatttg tcataaaatc catattcatc agcactataa
    24841 aaagcatctt gaaatttttc cagcacacct gctgctgaag tgtctgccat ggagataata
    24901 tccggcatat cttcgtgtgt taccaatttt ggggtgatca tttgtactgt tgctgttccc
    24961 gaagctacat tcacaatttt taagtcaata tttgctccag ttttgcggtt atagattttt
    25021 gcagcatttt caacatagtt tgtcagtttg ccgtttgcga catatacttc taatgtagtg
    25081 gcttttttta tcattggatc tgcgatgttt gctgttactt cttcgttagt ttttccacat
    25141 gcacttaagc tgaataatag ggtaatgttt agcaaagcta tcaccaattt gtatcttttt
    25201 ttcatgtcta tcccttcttt cttttcaagt tcttatataa aacgctttca cttatgtata
    25261 ttaacggaat tagtaacaca aatatttata taaaaaaata ttttacttgt cgttttggct
    25321 tttcattttt gttataatag tcattaatta taaatagaaa gctttttata taaaaagaga
    25381 aaggaaagtg gttcttttgt taacaaacaa ccaatcctcc aatcttgtca aaaaaacact
    25441 aacctattcc atagataccc atcttcattt atctgctgct ccctattttc gactactaat
    25501 aaatgaaagc gctaatttat atgctgaatt tgcacataaa tctatagaac tagataatcc
    25561 ttccctttta ttcattgata aacagcaaga agtccaaatc ttttctactc aaaaggaaac
    25621 acaaactttt atcattatcc agttttattt tgatgagcaa ttattagcac atattacggg
    25681 acaatctttt tctatagatc aagaaataac atctatcatt acttttctga aaaatgaaca
    25741 gttcaaaatt gattatctaa aacatagtaa gccagctatt tcctatgatc aggaaatcaa
    25801 ttcttttttc atactatgcc aacagatgag cattcatttg ctttccttat tagttactta
    25861 ttgtctgcaa aaaattcaat tgtcttcctt accaaggcat tatcaacagg aacttgcttt
    25921 attgacaata ccttcaaatg agaaagtcat tcctaaaaaa aagcatattc tttattcaga
    25981 tgaattagtt gatccaatca tacgatattt agaagaacat ctttcagaaa attttttgct
    26041 tgaacaatta gcccaaattt tttttatcag tccagccagc ttaaaaaaac attttagaaa
    26101 agtgaatgga aaaagtgtta ttagctattt taaagaacta aaaatggaaa aagcaaaacg
    26161 tctcgtgcta gaaaatgaat taacctatac agaaattgca gatatattag gatttcattc
    26221 gatccatcat ttttcttcag cttttaaaaa atatacaggg ttatcccctt caaagtatta
    26281 tctatcctta aaatagaaaa aaatttttag gttttatcca caaattattt ctctatattt
    26341 tctgtctatt caaaataaac aataattttc cggcacaatt atttgctgtt ttttaccata
    26401 acatagtacg atcaacgtag aaaaggagat gtttttatga aagttgttgt cattggcggt
    26461 gtagctggcg gtccttcatt tgccactcgt ttccgtcgat tgaatgaagc gcacgaaatc
    26521 attatctatg aacgcggaga aaatatttct tatgcaagtt gtgctttgcc ttattattta
    26581 ggaggtgtga tcactgaccg tgactcgctg atcgaacgta caccagaaat attgaaaaca
    26641 aaaaacaaca tcgatgtctt tactaaacac gaagtaacag caatcgatcc ttctactaag
    26701 cgattaacag ttaaagacct atccacaaat gaagaaataa aaacagatta cgataagttg
    26761 atcatctctt ctggtgctag accagattat ccggatattc ccggagtttt tgaagcagaa
    26821 aacggctttg tcctccgtag tgtgacggat gcggatcgaa tcaaatcgtt ccttgaagaa
    26881 aaaaatccac aacatgtcgt cattcttggt gcaggtgtta tgggtctgga attagctgag
    26941 aatttcaagc atcgcggctt agacgtgact ttaatcgatc aattgccaca agtcgctttc
    27001 ccttatgatc cagaaattgc taatttagtt tatgacaaat tgctgaaaga aggattagcc
    27061 gttcatttag aaacaagagt tactgagatc cgtgataaag gtcgagaaat agtattatca
    27121 gatggctccg tcctttctgc tgatatgcta atttttgctg ttggtgtttc tccgaagaat
    27181 gaagtggtga aagcaaccgg catacaatta tcagatacag gtcagatcat tgttgatgac
    27241 cagttacaaa ccaatctgcc ggacatctat gcgattggcg atattatcga aacgactagt
    27301 gtagtgactg gtcagccgat ccaaagtatg ctttccagtg cggccaatcg tcaaggacat
    27361 atgctggcag atattttaaa tggtacgcct atgcgctatc gcggatatat tggtgcaggt
    27421 gtcgcaaaaa tctttgatca tacagcaagt tatgcgggaa tgacagaaca tgaattaaaa
    27481 gcatcaggca taacaaatta taaaactgtt tttatcactc cctttgacca tgcctatttc
    27541 tatccagaag ctacaagatt aaatctaaag ctgatttttg atgcagatag cggtcgtatt
    27601 ttaggtggac aagcatttgg agaaaaaggt gtcgataaac ggatgggaga actttctgta
    27661 gcaatcaccg gaaacttgac agtctttgat ttgcctgatt tggagttgcc ttactctcca
    27721 ccgtattcta ctacccgtga cccgttgaat atagctggtt atgtcgcaat caatcaaatg
    27781 acgaatatcg tagaaacgat caaagcaagt gatatacccg aaaacgattt gaaagaagcg
    27841 ttctttttag atatacgtga acctaataaa gcaccttctg gcagtatctc ggcaacaaaa
    27901 aatattccaa tgaatgagtt acgagatcga atcaatgaaa tcccaaaaga taaaaaagtt
    27961 tacattactt tcagaagagg attgaatact tatacttctg cccgaatctt ggcaggtttg
    28021 ggtatcaaag cgattttgat tgaagaataa aaaaacgacc gcggtgggta gccgcggtct
    28081 aggagttatt tttacttgag gagtaaaaat gaaaaagtat atagggttgt tggttggtat
    28141 gtatatagaa tagaagataa atgtgaagaa attgtgcatt atttcttcac atttattagg
    28201 ttatagttta agaaagttta aacattgcgc aatttaatta ttttagctgt ttcttttcat
    28261 aaaaaaacat gttgtgactc tgagacaaat catagtccat agtgatgtct ctagagtaac
    28321 tacgcctaat attacgaggc atcatattaa tctatcagca ctagtaccta aactagcatc
    28381 cctttcgaat attttttctt atataataaa gtttgctttc actcctctaa tctcaccaaa
    28441 tcgactggct tgcgttgtgt gatactagga actgattggt ttagaacgac ttttctattg
    28501 taatcatatt tttcgccatc ctcgttgtct tctaatcctt caatgaatga tccctaatgt
    28561 gtgtattaaa taatttaatt tttttgttcc tatttattta a
//
LOCUS       DADLIO010000031        28076 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.031, whole genome shotgun sequence.
ACCESSION   DADLIO010000031 DADLIO010000000
VERSION     DADLIO010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28076)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28076)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28076
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.031"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            854..2023
                     /locus_tag="JOX41_001493"
     CDS             854..2023
                     /locus_tag="JOX41_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAY6449244.1"
                     /translation="MPNFTTEIMETLINKGDLDELFRCHLELAVNSLLQAELTAFLDY
                     EKYDRAGFNSGNSRNGNYSRSFRTEYGELNLVIPRDRNGKFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMSEISELIEKMYGHHYTPQTISNMTKIVSEDIIAFKERSLESRYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFSLAPTESAYVWKEILQDLKDRG
                     LKEVLLVVTDGLSGINDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     YQASSKEEANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEG
                     FNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
     gene            2496..3050
                     /locus_tag="JOX41_001494"
     CDS             2496..3050
                     /locus_tag="JOX41_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAY6449245.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGV"
     gene            complement(3223..3696)
                     /locus_tag="JOX41_001495"
     CDS             complement(3223..3696)
                     /locus_tag="JOX41_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAY6449246.1"
                     /translation="MRIKPIKDGEQLLFSSEENKPLYLDYVNHNLKIIIKENNLKHIT
                     LHGFRHTHCSLLFESGASVKEVYVRLGHTDIKTTMDDIYTHIAKKQTEETAIRFADFM
                     SSTEEKQGSLQKVKSMVKNEKSRLSLLDSLLNVELSVFFLFRSVCVFETVLILFF"
     gene            3708..4244
                     /locus_tag="JOX41_001496"
     CDS             3708..4244
                     /locus_tag="JOX41_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAY6449247.1"
                     /translation="MPARIHHISIVNRFIRPTFDFYHNILGLKLLMKTINQDDHTMYH
                     LFFSDNHHRVGTELTFFEVQEGNNQFFGTNTIERTILKVPSEASLHFWEIYFETQGVC
                     HYGIESFSGRPILRFEGPDATRLALVPLREFEDIDDYFPYVTDQIPTEHAILGIDAIQ
                     LRVQYSDATERELLSVGW"
     gene            4284..4655
                     /locus_tag="JOX41_001497"
     CDS             4284..4655
                     /locus_tag="JOX41_001497"
                     /inference="COORDINATES: protein motif:HMM:NF013098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAY6449248.1"
                     /translation="MTILENQDTQFYQEVQIIQDRENPVAIEGIGSVHHVAFGVENKS
                     DLQRIDKQLQERNFINSGIKDREFFVSLYYRDPNQLLIEIATGEGNLDAKAYENQSPR
                     FEEIPLFLPQYLNFIREQVEQ"
     gene            4939..6210
                     /locus_tag="JOX41_001498"
     CDS             4939..6210
                     /locus_tag="JOX41_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HAY6449249.1"
                     /translation="MKLSTQEKQLKNVSLKIPKNKISIFTSVSGSGKSSIVFDTITQE
                     AGRQLNDTYDSFTRLFLPKYSRPEVDEIDNLSTAIVVNQKKIGGSARSTLGTITNINA
                     LFRVLFSCFATPSLGYANAYSFNDPSGMCSVCQGIGKTIAFLIGLLYFSAIDNADFVF
                     SDPFTAEVLSGIEEQAKNHGYFVLVHNVNSAEDVKTIQRNWRFEGFIVVGVRVKEFLE
                     LNNVFDGPVVYIDTHLSKETLRELEQQMNRLFVNTNDYQASTLAVEHLIHYGHEKIAF
                     LSFDYIVGEPSVIQERHQAYIDTLKKYHLTFKSHWIYNNSEFERIYQELAEFTAIVVT
                     GDYLAAKLVKFLKNKNKRVMEQLSIIGFDDITFAELMDPALTTIRLNPGNKGAIAFHQ
                     LIGLAKQEEIKNQVLLLEGELISRDSVHKIK"
     gene            6455..7480
                     /locus_tag="JOX41_001499"
     CDS             6455..7480
                     /locus_tag="JOX41_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAY6449250.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLHIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            7774..8883
                     /locus_tag="JOX41_001500"
     CDS             7774..8883
                     /locus_tag="JOX41_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAY6449251.1"
                     /translation="MLDEFEKQNPDIKVEMETTPWDQYWVKLEAATTGGNMPDVVTMH
                     SSESYKYMSQNALMGLDDVIKENDIDMGNFTEGIADFYTLEDELYAIPKDASVVGLWY
                     NKELFDNAGVDYPDETWTWETLRQAAIDLTDESKGIYGFASHIGTETGYWPFIYQNGG
                     EVFADDNTKSGLNTPEAQEALAFYRDIALVDHASPTITELQDPDKLSRFQSGRLAMMI
                     EGNWFAPGFLKNDYLVENVASAVLPKGKVNATITNGLGWAASASTKYPEEVKKLMAFL
                     ASEDANKIQAETGASIPALKGFEDEWAASSDTIDLSAFGKMLEYGVPRPYNKDGLRAE
                     QAEVQIINRILSGEVTVEDGTAQIEKEVNAILSGN"
     gene            8966..9862
                     /locus_tag="JOX41_001501"
                     /pseudo
     CDS             8966..9862
                     /locus_tag="JOX41_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008378728.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            9878..10702
                     /locus_tag="JOX41_001502"
     CDS             9878..10702
                     /locus_tag="JOX41_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002579255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAY6449252.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINTFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGSKL"
     gene            10734..12044
                     /locus_tag="JOX41_001503"
     CDS             10734..12044
                     /locus_tag="JOX41_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HAY6449253.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSREYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            12192..13451
                     /locus_tag="JOX41_001504"
     CDS             12192..13451
                     /locus_tag="JOX41_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAY6449254.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            13461..14333
                     /locus_tag="JOX41_001505"
     CDS             13461..14333
                     /locus_tag="JOX41_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAY6449255.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            14345..15175
                     /locus_tag="JOX41_001506"
     CDS             14345..15175
                     /locus_tag="JOX41_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAY6449256.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            15215..17398
                     /locus_tag="JOX41_001507"
     CDS             15215..17398
                     /locus_tag="JOX41_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAY6449257.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDETVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLKERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            17459..18679
                     /locus_tag="JOX41_001508"
     CDS             17459..18679
                     /locus_tag="JOX41_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligo-1,6-glucosidase"
                     /protein_id="HAY6449258.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKDSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVWLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            18676..20136
                     /gene="gtfA"
                     /locus_tag="JOX41_001509"
     CDS             18676..20136
                     /gene="gtfA"
                     /locus_tag="JOX41_001509"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HAY6449259.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVIQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            20213..21319
                     /locus_tag="JOX41_001510"
                     /pseudo
     CDS             20213..21319
                     /locus_tag="JOX41_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            21641..21850
                     /locus_tag="JOX41_001511"
     CDS             21641..21850
                     /locus_tag="JOX41_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAY6449260.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMVSKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
     gene            21843..21992
                     /locus_tag="JOX41_001512"
     CDS             21843..21992
                     /locus_tag="JOX41_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HAY6449261.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
     gene            22027..22811
                     /locus_tag="JOX41_001513"
                     /pseudo
     CDS             22027..22811
                     /locus_tag="JOX41_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922412.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(23095..24180)
                     /gene="xerS"
                     /locus_tag="JOX41_001514"
     CDS             complement(23095..24180)
                     /gene="xerS"
                     /locus_tag="JOX41_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HAY6449262.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
     gene            24514..24747
                     /locus_tag="JOX41_001515"
     CDS             24514..24747
                     /locus_tag="JOX41_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HAY6449263.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            24744..25151
                     /locus_tag="JOX41_001516"
     CDS             24744..25151
                     /locus_tag="JOX41_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HAY6449264.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
     gene            complement(26288..26806)
                     /locus_tag="JOX41_001517"
     CDS             complement(26288..26806)
                     /locus_tag="JOX41_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HAY6449265.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
     gene            27924..>28076
                     /locus_tag="JOX41_001518"
     CDS             27924..>28076
                     /locus_tag="JOX41_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAY6449266.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELTASAFDKW
                     VKQSKTS"
BASE COUNT         9628 a         4253 c         5144 g         9051 t
ORIGIN      
        1 aattttctac gttttccttt tcatatatat taaatattac ggaaaattat ataaactaat
       61 ttagtgtttt gtttgtaatt cctaattttg ctccactttt agataatttt taggtctatt
      121 taactcatca gacattctat gctcattttt ctccaaattt gtttcaactc tttcgtactt
      181 aattttgcgt atttgaaaat tcttctttta gagtactttt attacgatac tagtatgata
      241 tatatctata gcaaacagtt aaaatcttcc taaaataagc gaatagcatt cctaaaacct
      301 ataaaatttt tagatgaagc gacaagtgga caattaataa actacttgaa catgaaatta
      361 tggatcacct ttcaaattta gaaaatggaa ttcttatact tattgcgcaa catttattga
      421 ttgcaaaatt atgtgacaaa aaaaactagt agaagaaaga ataatggctt gataataaag
      481 tactacctat taaaggtagt actttattta atttagtata aattaacata ctactatatt
      541 ttaggtttca tattatataa attaataata tactaccatt tgttggtagt ataatttaaa
      601 ggtaataagt tattctttta ttactatgtt tgggttttat agcaaagaaa gtttaataag
      661 agtttggacc tagcaaacaa tattaatgag gtcattaaat cttattatct ttagtgatat
      721 aacgaaatat ctacacagac aaaatgatag cgtaaaatat tttgtgtaaa tagatattta
      781 gggtagaaaa aaagaaagtc cattctgtaa aattaaagtt accacaaccg aaattttata
      841 ggaggacttt ctcatgccca attttactac agaaattatg gaaacactaa tcaataaagg
      901 tgatttagat gaattatttc gatgtcattt agaattagct gttaattcat tattgcaggc
      961 tgaattaaca gcttttcttg attatgaaaa atatgatcgt gctgggttca attcaggtaa
     1021 ttcccgtaat gggaattatt cacgttcatt cagaacagag tatggagaat taaatttggt
     1081 aattcctaga gatagaaatg gtaagttttc tcaacaaact ttacctgctt ataaaagaac
     1141 caatgactct ttagaaacca ctattattca gctatttcaa aaaggaatta ctatgtctga
     1201 aatctctgaa ttgattgaaa aaatgtacgg gcatcactat acgccacaaa ccatttcaaa
     1261 tatgactaaa atagtttctg aagatattat tgcctttaaa gaaaggtcct tagaatccag
     1321 atactctgtc atttttatgg atgctactca cattccttta aaaagacaaa ctgtttcaaa
     1381 agaagcagtt tatattgtaa ttggcattcg attagatgga accaaagagg ttcttgggtt
     1441 tagtcttgct ccaactgaat ctgcttatgt ttggaaagag attcttcaag acctaaaaga
     1501 ccgtggttta aaagaggttt tattagtcgt aactgatggt ttaagtggca ttaacgatag
     1561 tattcatagt gtttatccaa atgctcaatt tcaacaatgt tgtgtccata tatctagaaa
     1621 tatcgctcat aaggttcgtg ttagtgatcg acaagaaatc tgtagcgatt tcaaattagt
     1681 ttatcaagca agttcaaaag aagaagcaaa taatcaaata aggtttatga tagataaatg
     1741 gaaaaagcag tatccacgag tggttaaatt gctcatgaat cctgctatat taacctttta
     1801 taatttccct ccgtcaatca gaagaactat ttattcaact aatttgattg aaggttttaa
     1861 caaacaatta aagaaatata ccaaaagaaa agagcaattt cctaatgaag aatctctgga
     1921 gagatttcta gtatctcaat tcaacaacta taatcaaaag tttctatgcc gagttcataa
     1981 aggttttaaa gaaatacatg atacattaga atcaatgttt taacttgatc aacagaatgg
     2041 gcttttccat ttacacaaaa ttattgacgc tcccgacaaa attatgatct tgcgtaaagt
     2101 tataaaatat taataaaaat attttattaa tgaaaagctt ggtagcacgg ttattcatat
     2161 gctaatttat ttcactttat agtaagggga gttcttagta tattgttcaa acttaaattt
     2221 catataattt aattatgtaa attagctatt ctaagaactt ctacggataa ctgcccgtct
     2281 aaaatttaaa taagagctta gaatcttcat ataagtaagg ttaatttttt tgtacaaaaa
     2341 agtcggaata ttctgagtta ctgaaatgat ataaaatcat aaactaaatc ccttgatttt
     2401 attgactttc aaaagtttat atatataagt taatgattat ggtaaaatat atacataatc
     2461 attaactcag aatattttta agaagggaaa caatagtgag ctataatgta caaccgttaa
     2521 ggacaaatga agagatacaa gattttcagt tttggctaag aagaacaagt aatccggaaa
     2581 gagatagttt tttatttttg tttggaatca ataatgggtt acgtatgtca gatattatag
     2641 gattaaaagt tggagatata cgaggcaaaa gtaagcctat tattgttgaa cataaaacag
     2701 gtaagcgaaa accgattttt atagataatt tgagagaaga aattttatta tatactgaag
     2761 gtaaagaaga aaatgattgg ttatttccga gtcggcaaca aggtcgacat ataacaaggg
     2821 atcgtgtcta tcagatatat gcagatatag cagaaaaatt aggacgagat gatataggaa
     2881 cacatacatt aagaaaaact tttgggtatc actactacaa gaaaactaga gacattgcta
     2941 ccttaatgtt tatttttaat catagctcgc aagcaattac aaaaaggtac attggtataa
     3001 ctgaagatga aataggagca tcacttcgtg gatttaaact aggtgtataa tttaaaaatt
     3061 tttataaaca gtaaagacaa agattaaaag ctatttttat ctagaacgat tttatttcat
     3121 aaagttcgcg gaataaaagc tggggttact ggtacttggt ataggttcgt gttatataaa
     3181 ctaagtaatt aaataacatt tttaggttgg aaaaggatga aattaaaaaa agagaatcaa
     3241 tacggtctca aaaacgcaaa cgctgcggaa taagaaaaat actgataact caacgtttag
     3301 cagactatct aatagggata gtctgctttt ttcgtttttg accatacttt tgaccttctg
     3361 caaacttcct tgcttttcct ctgtagaact catgaaatct gcaaaacgaa ttgccgtttc
     3421 ctctgtctgc tttttcgcga tatgggtgta tatatcatcc atagtggttt taatatctgt
     3481 atgtccaagt cgaacataca cttctttgac agacgcacca gattcaaaga gcagactaca
     3541 atgggtatga cgaaaaccat gaagtgtgat atgttttaag ttattctctt taatgatgat
     3601 tttcaaattg tgatttacat agtctaaata aaggggctta ttttcttctg atgaaaacaa
     3661 aagttgttca ccatctttta taggtttgat tctcattttt agatattatg cccgcacgta
     3721 ttcatcacat ttctattgtg aatcgcttta ttcgaccgac atttgacttt tatcataata
     3781 tactcggttt aaaattacta atgaaaacaa ttaatcaaga cgatcatacc atgtatcacc
     3841 tgtttttttc agataatcac caccgtgtgg gaactgaact gacttttttt gaagtacaag
     3901 aagggaacaa ccagtttttt ggaaccaata cgattgaacg aacgatacta aaagttcctt
     3961 ccgaagcatc attgcatttt tgggaaatat attttgaaac acaaggcgtt tgccattatg
     4021 gaatcgaatc attttctgga cgacctatct tacgttttga agggccagat gcaacacgat
     4081 tagctttagt tcccttacgc gaatttgaag atattgatga ttatttcccg tatgtcacag
     4141 accagatccc tacagagcat gccattttag gaattgatgc cattcaacta cgcgtacaat
     4201 attccgatgc gactgaacga gagttattgt cggtaggctg gtagcacaaa gaatacgtca
     4261 gtttcttttc gggtcatcaa cgagtgacaa tcttagaaaa tcaagacact cagttctatc
     4321 aagaagttca gattattcaa gatcgtgaga atccagttgc cattgaaggg attggtagcg
     4381 tccatcatgt tgcgtttggc gtagaaaata aatctgattt acaacgcatc gacaaacaat
     4441 tacaagagcg caattttata aattcaggaa taaaagatcg tgaatttttt gtatcacttt
     4501 attatcgtga cccaaatcaa ttattgattg aaattgctac aggggaagga aacctagatg
     4561 caaaagcgta tgaaaatcaa agtccacgct ttgaagaaat tcctttattt ttaccgcagt
     4621 acttaaattt cattcgtgaa caagtggagc aataattagc taatcaaatc catgacgaag
     4681 agtaagaggt tgactcataa gtcaaaaaat aaagaaaaac gcatcaaatc cattctaaag
     4741 aatgttgatt tgatgcggtt cctattttta taaactatca ttttcgacta ataaaactac
     4801 ttatgagtca gcctctcttt ttttcttgat ttttatacct ctttctaggt aaactaaaca
     4861 tctgccaaaa ataccgtgtc tcattgaaac attctcaact atttcaaaat aaaggggagt
     4921 accaaatgaa cgagtatatt gaaattatcc acgcaagaga aacaacttaa aaatgtcagt
     4981 ctcaaaattc ccaaaaataa aattagtatt tttaccagcg tatctggttc aggaaaatca
     5041 tcgattgttt ttgatactat tacccaagaa gctggtcgtc aactgaatga cacctatgat
     5101 agttttaccc gtttattttt acctaaatac agtcgtccag aggttgatga gattgataat
     5161 ctttctacgg cgattgtggt caatcaaaag aagattggtg gcagtgcgcg ctcaacgtta
     5221 gggacgatta ctaacatcaa tgcgttattt cgtgtgttgt tttcatgttt tgcaacacct
     5281 agtttaggat atgcaaatgc ttattcattt aatgatccta gtggaatgtg ttctgtctgt
     5341 cagggaatcg gtaagacgat tgcattttta ataggattgc tttatttttc ggctattgat
     5401 aatgctgatt ttgtattttc tgatccattt accgcagaag ttttgtctgg aattgaggaa
     5461 caggcaaaga atcatggtta ttttgtattg gtgcataatg ttaattcagc agaagatgtt
     5521 aaaactattc agagaaattg gcgttttgag gggttcattg ttgttggtgt acgtgtaaaa
     5581 gaatttttgg aattaaataa cgtttttgat ggtcctgttg tttatattga tacgcatctt
     5641 tcaaaagaga cattaagaga acttgaacaa caaatgaatc gtttatttgt aaatacaaat
     5701 gattaccaag ctagtacatt ggcagtggaa catttgattc attatggtca tgagaaaata
     5761 gcgtttcttt cttttgacta cattgtaggt gaaccaagtg ttattcaaga acgacatcaa
     5821 gcttatatcg atacattaaa gaaatatcat ttaaccttta aatcgcattg gatatataac
     5881 aactctgaat ttgagcgaat ttatcaagaa ttagctgaat ttactgcaat tgttgttact
     5941 ggagattatt tagcggctaa attagtaaaa tttttaaaaa ataagaataa acgagtgatg
     6001 gaacaattat cgattattgg atttgatgat attacttttg cagaattaat ggatcctgcg
     6061 ttgacaacaa tacgactaaa tccaggtaac aagggggcga ttgcttttca ccaactgatt
     6121 ggactggcca aacaagaaga aataaaaaat caagtactac tattagaggg agaattgatt
     6181 tctcgagact ctgttcacaa aatcaaataa aaaagctctg tgaaataagt atagttaaca
     6241 ataaaatatc cgaacgatag agagaatgaa ctgtgatcta gcagttcctc gtcgcaaatt
     6301 cactagaatt agcattattt actctaaatt gttcggatat tttttcttgt ttttaattat
     6361 gattacagtg cctattttta acgaaatttg cttattttca aaatgtatga ttatatgtta
     6421 gtaaacactt tcaaatatga aaagaggagc tattatggta ggaattaggg atgttgcaaa
     6481 acgggcgggt gtgtccattg caacagtatc gcgcgtgcta aatgaggatc cgacactttc
     6541 agtaaccgat gaaaccaaac gaaagattgc agaatcggtt aatttttatc attatgtcaa
     6601 aaaaagtccc gttgcaaaaa atttaacaaa tattgcatta ataacgacag tttctgaagt
     6661 agatgagttg gaagatccct attttcgaac gattcgcaga gggattcaag tcgaagcaga
     6721 acaaagcaaa gtcaatttga agaaaattat tcgtttgtca gaaacaccgt tggagcaaga
     6781 cgatttgcta aaatgtcaag gtgtgttgat tattgggcag gtgctatctt ctgtgattga
     6841 agaagtatca gcaattaatt cgaatgtcgt agtgattgat gaccctagta ttgaagctga
     6901 agtagatgca gtttatactg atttaacaaa agcaacgaat cagcatttag atcgattgta
     6961 taaaaaagga caccgaaaca ttgcgtttat cggaggagga cgtgttcgtt tagatagcca
     7021 aggaaataaa cacgtgtcag atgatgatta tcgaaaaata gcctatgaga cgtggatgaa
     7081 acaaaaagga ttagaaaaat atagtcaaat ttatttagaa ggctggacca cacttgacgg
     7141 aatgcaggca gcagatttac ttttgaaaaa acatgctaaa gataagttgc cgactgctat
     7201 catggtagga aatgatccta ttgctgtggg ggtttatcgt tcacttcaaa aaaatggtct
     7261 acatattcca gaagatattt cgattgtgag ttttgataat attgaagttg ctgaattttt
     7321 aacacctgca ttaaatacgg tgaatgtgaa tacagaagaa attggaaaac tagcagttcg
     7381 catggttaat gaacgaataa aagaagttag aaatgtttcg atcaaagtga ttgtttctaa
     7441 taatattatt gttagagaaa gtgaaaaaaa tatcgattaa aaaagtaaac atccaaaaaa
     7501 gggtgtttac ttttttgttt actaatattt ttagtaaaaa atctcgacaa aacattaagt
     7561 aaacagttat ggtgttgtta acaaaaagaa aacgcattca aaacaggagg aattaagatg
     7621 aaacatttca aaaaaatagc tttaacaggg atagctgttt taactgggac attactcgca
     7681 gcatgtggtg ggggagatag taattctaaa gacgggcaag taactttaag ctatgcgagt
     7741 tgagatactg accaagctcc aggactaaga aaaatgttag atgaatttga aaaacaaaat
     7801 cctgatatca aagtagaaat ggagacaacg ccttgggatc aatattgggt taaattagaa
     7861 gctgcaacaa cgggaggtaa tatgccagat gtagtaacca tgcactctag cgaatcctat
     7921 aaatatatgt cacagaatgc tttgatggga cttgatgatg ttatcaaaga aaatgatatt
     7981 gacatgggaa actttactga aggaattgct gatttctata cgcttgaaga cgaactatac
     8041 gcaatcccta aagatgcttc tgtagtgggg ctatggtaca acaaagaatt atttgataat
     8101 gcaggtgtcg attatccaga tgaaacatgg acatgggaaa cactcagaca agctgcaatt
     8161 gatttaacag atgaatcaaa aggcatctat ggttttgcat cacatattgg aacagagact
     8221 ggctactggc catttattta tcaaaatggg ggagaagtat ttgccgatga caatacaaaa
     8281 tcaggtttga ataccccaga agcacaagaa gctttagctt tttatcgaga tattgcactt
     8341 gttgatcatg cttcaccaac aattacagaa ttacaagatc ctgataagtt aagtcgtttt
     8401 caatcaggta gattagcaat gatgattgaa ggaaactggt ttgcaccggg atttttgaaa
     8461 aatgactatc tagttgaaaa tgttgcttct gccgtgttac ctaagggaaa agttaatgca
     8521 acaattacaa atggacttgg ttgggctgcc agtgcgagta caaaataccc agaagaagtg
     8581 aaaaaactaa tggcattttt agctagtgag gacgccaata aaatccaagc ggaaacgggg
     8641 gcatcaatcc cagcactaaa aggctttgaa gacgagtggg ctgcttcttc agatacaatt
     8701 gatttgagtg cttttggaaa aatgttggag tatggagtcc ctcgtccata caataaagat
     8761 ggattacgag ctgaacaagc agaagttcaa attattaacc gtattctgtc tggtgaagta
     8821 actgttgaag atggaaccgc tcaaattgaa aaagaagtca atgcgatatt gagcggaaat
     8881 taaattagtt aattatacaa tatacaggcg aaaggattct atttcgtctg tatattaatg
     8941 gatgaatacc aaaaaggggg atattatgaa aaatcgaatt tttggaaaat atcgtaaaga
     9001 tcaagtgata tggggctata tttttatttt tccaacggca ttaggattaa ttttattaaa
     9061 tatatggcca gcaattcaaa cagcaatttt aagttttcaa aaaacggtag ggttcggtga
     9121 tactgaatgg gtcggattaa gaaattacca aaaaatgttt gcagacggtg aagtttttca
     9181 gtctttatta aacacattaa tttatgcagt ggtttcgata cctagtattg ttgtattatc
     9241 cttgttggtg gcagttttaa tgaatagaaa agttaaagga ttgtcgattt atcggacaat
     9301 ttattttcta ccagtcgttg ctgcaccatc cgcagtcgca atgatttggc gctggatgtt
     9361 caataatgat tatggactga ttaataacat gttggctaaa ataggtctcg atggaccagc
     9421 atggttaacg gatccatcga ttgcgattta ttctattatc attgtaggag tttggagtgc
     9481 tattggttat aacatggtgt tattactagc cggcttataa gaaattccta aagattatta
     9541 tgaagcagcg gaaattgatg gtgctagtcc aatccagcag tttttcaaca ttacgttacc
     9601 attagttaca ccaacattat tttttgtagt tgtaacaaca gttatcaatg ctttccaagt
     9661 atttgatgtt atttttatga tgattactcc taatagtacc gccatgttta aatcacaatc
     9721 attagcctat ttattctata aacattcatt tattttaaat gacaagggat atggttcggc
     9781 aatcgttatg ttccttttag tgattatatt aattattact gcaattcaaa tgaagttgca
     9841 gaaaaagtgg gtaaactatt aaggaggcta tcaaattatg aaaaataaat ttttttcaaa
     9901 tgcgccaatc catatcatgc ttattttagg tggtattgca atggcattac cttttatttg
     9961 gatgatttta acttcaggga aaacgttggt tgaatctacc caaattccac ctacaatttt
    10021 ccctgagaaa tttcagctaa gtaactatca acaagtactt gatttattac cattcatggc
    10081 tttttatatc aatacatttt taatggttgt tggacgagtg attggctcgg ttttattttc
    10141 agcaatggct gcatatgctt gtgcgcgtct aagttttcca gggaaaaata tccttttcag
    10201 cttagtactt attcaaatga tgattcccgg ttccattttt attactccac agtatttatt
    10261 agcacaaaaa ttgggtattt taaatacaat tccagcatta atattaccag gggtagttag
    10321 tgcgtttggt acgtttttat taagacaatt tttcttaggt ttacctgatg aattggagga
    10381 agcggcctat ttagaaggtg ccaatatttg gacgatcttt ttcaaaatta tgttgccgct
    10441 tgctaaatca ggattggttg cacttggaat attcacagcg ttgtttgcat ttaaagattt
    10501 aatgtggcca ttgattgtca atacttcaat tgataagatg cctttagctc cgggattagc
    10561 aaacttacaa ggacaatatg ccacgaactt cccacaatta atggcaggtt cgttattagc
    10621 aatttggcca atagttgtga tattcatcgt tttccaaaga aaattcattg aaggaattgc
    10681 tacaacaggt agtaaattat aaaactatta attagtgatt ggagagtaag tacatgacaa
    10741 aaattacatt tattggtgca ggaagtacta tttttgcaaa aaacgtatta ggcgatgcga
    10801 tgttaactcc aagtctacaa gatgcacata ttgcattgta cgatattgat gaaaaacgac
    10861 taaaagaatc aaatttaatg cttaaaaata ttaataaaaa ttcgaatgaa aatcgtgctg
    10921 atattgtttc ttattatgat cgcaaagaag cgttaagaga ggctgatttt gttatcaatg
    10981 ctattcaagt gggtggttat aaaccttcaa cagtgattga ttttgatatt cctaaaaaat
    11041 atgggttgcg acaaactatt ggtgacacca tggggattgg tgggattttt agaaccctac
    11101 ggacactacc agtaatgtta gactttgcta aagaaatgga agaagtttgt ccaaatgctt
    11161 ggttattgaa ctatacaaat ccgatggcga tgttaaccat gggtgtttta aaagcgacga
    11221 gtattaagac tgttggttta tgtcatagcg ttcaagtatg cgtaccagaa ttgtttgagc
    11281 atttaggaat agccgatcaa tatgacttaa atgactttca atggaaaatt gcaggcatta
    11341 atcatatggc attcttgttg gaaattacaa aaaatgggga agatttctat ccaacaattc
    11401 gtcagttagc tgcagaaaaa ccaaatccac atccagattc tgtacgtttt gaattgttga
    11461 aacgttttgg ttactatatt acagaatcaa gtgaacacaa tgcagaatac catccatact
    11521 ttattaaatc aaaataccca gaattgattg acgaattagg gattccgttg gatgaatact
    11581 tacgtcgttg tgaacaacaa attaatgatt gggaaagcat gcgagaggac attgtaaata
    11641 atggggagtt aacacatacg agaagccgtg aatatgcttc atatatcatg gattctatta
    11701 cgacaggaac tccgtcagtg attgcaggaa atgtcttaaa taaaggctta atcacaaact
    11761 taccgacaga tgtttgtgtg gaagtacctt gtttagtcga taaaaatggc gtgcaaccaa
    11821 cctatgtcgg tgaattgcca acacaattag ctgctttaaa tcggacgaat atcaatgttc
    11881 aagaactgac agtagaagcc gctttaacac tagataaatc aaaaatttat caagcagcgt
    11941 atttagatcc acatctatca tctgaattgt ctttaacaga tatcaaaaat ttagtggatg
    12001 atttaatcga agcacatggg gactatttac ctgaatataa ttaaaaagaa gctgaaagag
    12061 taaggaattt tcaattcctt actcttttct tagttaaatt tagtaaaaat attgacaaaa
    12121 cacttagtaa acagttacat tagtgttaac aaaaagaaaa cgcattcaaa ttgtataagg
    12181 aggagcataa aatgaagtgg tctaaaaaaa ttattttagc ttgtatagca ctaggagcaa
    12241 cgatctcttt gactgcttgt ggaaaaaatc aggaagatgc aagcggtaag gtagaaatag
    12301 agttttttaa tcaaaaaaaa gaaatgactc aaacgattca ggagattgct aaagattttg
    12361 aagcaaaaaa ccctgatatt catgtaaaag ttgtggatgt accgaatgct ggtgaagtaa
    12421 ttaaaacacg tatgcttgca ggcgatgtac cagatgtcat taatctttat cctcaaagta
    12481 tagaattgaa agaatgggcg aaagctggtt atttagagga cttaaccgaa gaaccgtatt
    12541 tagagaatat caaaaatgga tatgcacaac gttttgctat tgaggatcgt gtatatagca
    12601 taccattaac cgctaatgtc tatggttttt actataacaa aactgctttt gaggaaatgg
    12661 ggattcaagc accagaaact tgggcagaat ttgaaaaaat agtagctgag attaaagatc
    12721 aaaacaaagt accgtttgcg attgcaggag cagaaggctg gactttaaat ggttatcacc
    12781 aactagctat agcgactgct gctggtggtg aagaggaagc gaacaatgtt tggcgtttct
    12841 cagaagttaa tggaattaat gctgaaagca aagaaatgca aaaagatttt aatcgattag
    12901 atttgttaag agaaccaaaa gctttgcaaa acaactggca aggtgccggt tataacgata
    12961 cagtagttac ttttacaaaa ggtgatgcgt tgattatgcc gaatggttca tgggcaatgc
    13021 cgatgattca ttcacaaaat ccagattttg aagtaggaac ttttcctttt ccagcagatg
    13081 aagcaggtca aagtctaacg attggcgcag gagacctagc cttatcagtt tctgcaactt
    13141 ctcaacataa agaagaagcc aaacgttttg tagaatatat gacaacacct gaagcgatgc
    13201 agaaatatta tgatgtagat ggtgcaccgt gtgctgttga gggcgttatc gagaatactc
    13261 aggattcacc attaagtggt ttaactgaac ttgcttttac tgatcgtcat ttagtttggt
    13321 tagccaaaga ttggaatagt gaaaatgatt tttatacctt aacaacaaat tatttacaca
    13381 atggcaatca aaaagccatg attaacgcat taaatgcttt ctttaatcca atgaaagctg
    13441 acggaaggta ggaaaataaa atgaaaataa aagaaatttt aaatcgttac tgggcaatca
    13501 tttttgtagc aattccaatt attttgcaga tgattttttt ctactttcca atggttcaag
    13561 gtgcttttta cagtttaact aattggactg gtctgactta taattttgat tttgtgggtt
    13621 tgaacaatta taagattctt ttttctgatc cgaagtttat caaatcgatt ggcttcactt
    13681 taattgtgac gctttgcatg attgctggac aaattggttt tggtattttg attgcgcggg
    13741 cgttgaacgc aaatattaaa gggaaaacat tctttagagc atggttcttt tttccagcgg
    13801 tcttatcggg cgtggttgtt tctttagtat ttaaacaaat ttttaactat ggtttaccaa
    13861 aaattggtag tatgttaggc attgaatttt tacaaaccag tcttttagga acaacatggg
    13921 gagcgatttt tgcagtaatt tttgttttac tttggcaagg aattgccatg ccagtcatca
    13981 ttttcttagc gggttttcaa agtattccac aagaaattat tgaagctgct agaatggatg
    14041 gggcgaatga taagcaaatt ttttggaata ttgaaatcac ctacttatta ccaagtattt
    14101 caatggtatt tattatggca ttaaaaggtg gcttaacagc atttgatcaa atttttgctt
    14161 taactggtgg tggaccaagc gatgccacaa catctttggg gttacttgtt tataattatg
    14221 cttttaaaaa caatcagttt ggttatgcga atgctattgc tttagtctta tttatcttaa
    14281 ttgggattgt ttcactggca caattaaaat tatcgaaaaa atttgaaatc taggaggttt
    14341 cccaatgaaa acatcaaaag aaaaaaatat ttctaaatac ttgcttttat tattaggggg
    14401 cttcatgatt ttagttccct tagtttcaac gctattcggt tcatttaaaa caacacccga
    14461 tattatgaat aatttctttc gttttcctaa tccagcgact ttggaaaatt tccgaagatt
    14521 gttagcggat ggaattggtc attacttttg gaattcggca atcatcacaa tcattgcagt
    14581 agttgctgtg acagcaatta ttcctatggc tgcttattca ctagcaagaa aaatgactcg
    14641 tgggaaagca tacggattga tgtatttatt tttaatttta ggaatttttg ttcctttcca
    14701 agtaattatg attccgatta ccgttatgat gagtaaaatt ggtttagcaa atatgtgggg
    14761 attaatctta ctctatctca cttatgccgt accacagaca ctatttttat atgttggttt
    14821 tattaaacta aatgtgccta tcagtctgga tgaggctgct gaaattgatg gggctagtca
    14881 ctttacaact tatttcaaaa ttgttttccc aatgttaaaa ccaatgcatg cgacgactat
    14941 tattcttaat gctctatggt tttggaatga tttcatgcta ccattattaa ttttaaatcg
    15001 tgattctaat atgtggacac taccattgtt tcaatataat tatacgggac aatattttaa
    15061 cgactatggt ccaagttttg cttcctatac agtaggaatt gtcacgatta cactagttta
    15121 tcttgctttc caaagaagta ttatagctgg aatgagcaat ggagcagtga aataaccaat
    15181 aaattattct cattataaag gagttcataa acttatgatt atatttgaca atcacacaca
    15241 aacatttcat ttacaaaata aaaaaattag ctatctatta ggaatcgaag aaaataatta
    15301 tttaacgcat ctttattttg gaaaaaagat tacgcactat tctggtgggt atcgctaccc
    15361 ccgaacagat cgttccttct cacccaacaa tgcaaatgcg caagatcgtt tattatcttt
    15421 agacacatta ccattagaat ttccaggata tggacatggt gattttagag aaccggcgca
    15481 taatattaaa ttaggaaacg gtagtcgtgt aaatgatttt cgttatgata gctacgaaat
    15541 tcaaaaagga aagcccagct tagcgggatt gccagcctta tatacggaag atgatgatga
    15601 agctgaaacg ctgattattc aattgaaaga cgcgattagt ggattgactt tacagttgtt
    15661 ctacacaatt tatcaaaatc acagtgtaat tattcgttct acgcaattag taaataatag
    15721 tgatgaaaca gtggagatta accgcttagc tagtcaatca attgattttc caaatcgtcc
    15781 actcgagtta attcatttaa atggtacctg ggcaagagaa cgtcaaatga ctagagaaaa
    15841 aattcataca gggataaaag tattagatag taaacgcgga tcaagcagcc atcaacaaaa
    15901 tccgtttgtt gctttagtag atgccaaaac agatgaattt caaggagagg catatggatt
    15961 taatttagtt tatagcggta atcacgaaac ggtgattcaa aaagatccat ttgaccaaac
    16021 acgggtcatt atgggaatta attcatttaa ttttggttgg caactaaaaa ctggcgactc
    16081 atttcaaacg ccagaagtcg tgatggttta tagtaatgaa ggtctgaata cgttatcaca
    16141 gacgtatcat gaattgtata atcaccgttt aattcgtgga aactatcgtt taaaagaacg
    16201 tcccacgtta atcaacaact gggaagcaac gtattttgat tttaacgaag aaaaaatcat
    16261 gaatattgtc gatgatgcga agaacttggg cattgaaatg tttgttttag atgatggttg
    16321 gtttggcggt cgtgaaaatg acttcacttc attaggtgat tgggttgaaa cagaaggcaa
    16381 acttgcttgt ggtttggaaa atttagccaa gcaagtgcat gataacggga tgaaatttgg
    16441 gatttggttt gaaccggaaa tgatttctga agatagtgaa ctatttcgag cacatccaga
    16501 ttgggcattg ggtattccag gtcgtgaccg ctcaattagt cgaaatcaat atgttcttga
    16561 tttttcaaga caagatgttc gtgataatat ctatcaacaa atgacggcga tttttgatcg
    16621 tgtaccgatt gattatgtga agtgggatat gaatcgaaat atgacagaag tctattctgt
    16681 cttgttggac tcaacgatgc aaggtgaagt ggctcatcgt tatatgttag ggttatatga
    16741 atttttagaa aagttaacaa cgaattatcc aactatttta tttgaaagtt gttcgggtgg
    16801 aggcggtcgt tttgatgcag gtttcttgta ttacatgcca caaacttgga cgagcgacaa
    16861 taccgatgcc gtggctcgtc tgaaaattca atatggaacc agcttagtgt atccaatttc
    16921 aagtatgggt gcgcatgttt cagcagtccc aaatcatcaa acaggaagag aaacgagttt
    16981 aactattcgt ggcaatgctg cgatggctgg tgtttttggt tatgagctag atctaacgca
    17041 attaacttct gaagaaaaag cagaaattaa agaacaagtt gccttttata aaaagcatcg
    17101 ccaacttttg caatatggaa ctttttatcg cttggaaagt ccgtttgaag gcaatgatac
    17161 tgcatggatg tttgtctcaa aagaccaaac agaagccatg gtcttttatt tccgagtatt
    17221 agcagaagct gcgcatccat tagtcacatt gaaattagca ggattagcag aagaagcaac
    17281 ttatcaaatg gaagatgtaa catttgctgg cgatgaattg atgaatctcg gtttttatat
    17341 tgactcagaa ctacatggtg attatgcgac acaacgcttt tatttgaaac agatatagta
    17401 gcttgaattt acaatataag tgcaacacca aaagagactc attccaaacg aagaaaatat
    17461 gttttattta cacgcattta ctaaaaagca gcctgatttg aattgggaaa atgaagaagt
    17521 acgtgaagaa atctatgcaa tgattaacta ttggttagat aaaggactag gcggatttag
    17581 aatcgatgcg atattaaaca tcaaaaaaaa actagagtat ggcatctttg aatctgatgg
    17641 agaagatggg ttagccttca ttgggccctg gattcttaat cagtcgggca ttgaagtgtg
    17701 gttaaaagaa atgagagagc ggacatttaa accacataat agtatgacgg tagcagaagc
    17761 cgatgttcct aatgaacgtt tagatgaata tattggtgaa gatggctatt attcgatggt
    17821 ttttgatttt agttatacgg atattgatgt acctgaaact ggtgaatggt ttaaagatag
    17881 ccaatggaca tggacggata tgcgtaccaa tatttttacg aatcaattag ttacgcaaga
    17941 taaaggttgg ggcgccttat atttagaaaa ccacgatcaa ccacgttcaa ttaataaata
    18001 tattccagaa gaatggatca atgattatag taaaaaaatg ttggcgacgc tttttatgtt
    18061 actaagaggt acccctttta tttatcaagg acaagaacta ggaatgacca acatagaaat
    18121 ggcatcatta gaagattttg atgatgtagc tacgcattct cagtataaac gggcattaga
    18181 atatggattg gcaccagagc aagcattgaa agctgtcaat aaacgaagtc gggataattc
    18241 tcgcacacct atgcaatgga atacgcaaaa aaatgccaga ttctcaactt ctgataatgt
    18301 atggttaaaa gtaaatccta attatccaga actcaatgca gaagctcagt taaccaatca
    18361 acagtcggta ttcaattatt atcatcaatt aattaaatta agaaaaaata gtgtatacaa
    18421 agacgtgcta atctacggac aatttctacc agtgaaagat aaaaatgaac atattttgct
    18481 ttatgaacgc caattagaag ataaaatcgt attagttatc ttaaacgtta cagcaacaga
    18541 acaagaatat tatgtagatg aacagtacca acaagtatta atcaataatt atgaagatgt
    18601 tttattagat caaagtcgaa aattgcgttt acgaccgttt gaaagtattg tattagctaa
    18661 ttatggagga caattatgaa aattaaaaac gaagcaatgc tcatcaccta tgcagatagt
    18721 ttaggaaaaa acatgggcga attaaaacaa gtcttagaca aacatttaca aggtgttatt
    18781 ggtggtgtac atctgttgcc tttttttcca tcgacaggtg atcgaggctt tgcgccgagt
    18841 gattatacga cagttgatcc agctcttgga acatgggaag atgtggaagc attaggtgaa
    18901 gattattatt tgatgtttga ttttatgatt aatcacattt ctcgtgaatc aaaatttttc
    18961 caagatttca aaaaaaacca tgagcagtca ccatacaaag aaatgtttat ccgtattcat
    19021 gaatttttcc cagaaaatcg accaacacaa gaagatattg atttaatcta caagcgtaaa
    19081 gacaaagcgc cgtttcaaac ggtagaattt gcggatggta cgacagaaga ggtttggaat
    19141 acctttgggg aagaacaaat tgatttagat gtgaccaaag aagttgtgaa agaatttatt
    19201 cgagaaacca tcaaagatat ggcgaaccat ggctgttctt taattcgatt agatgcgttt
    19261 gcttatgcga ttaaaaaatt agataccaat gatttcttcg tggaaccaga tatttgggaa
    19321 cttttagacg aagtgcgtca agaagcagcg aaatatgacg tcgaattatt accagaaatc
    19381 catgagcatt attccattca aatgaaaatt gccaatcatg attattatat ctatgacttc
    19441 gccttgccaa tggtcactct gtattcactt tatagtggaa aatcagaacg tttagccaat
    19501 tggttgaaaa tgagtccgat gaagcagttt acaacattgg atacgcatga tggaattggt
    19561 gttgtggacg ctcgtgattt attaacagat gaagaattgg attacacctc tgaggaattg
    19621 tataaagtcg gggcgaatgt gaagaaggtc tattcaagtg ccaattacaa taatttagat
    19681 atttatcaaa ttaacagcac ctattatagt gcattaggcg ataatgaccg tagctatctg
    19741 ttagcacgtg cgattcaagt atttgcgcca gggattccac aaatttatta cgttgggtta
    19801 ttagcaggaa aaaatgatat tgaactgttg gaagcaacga aagaagggcg taatattaat
    19861 cgtcattact atgatttagc cgaaattgaa gaagaagtgc aacggccagt gattcaacaa
    19921 ttatttgcac ttttaaaatt tagaaatgaa tctgcggcgt ttgatttgga tggaacgatt
    19981 gaagtagcaa cgccatcaga atcagaaata gtgattacac gtaaaaataa aaacggtagt
    20041 gatagtgcaa cattaacggc taacttggat acgaaagaat ttatcattga gtctaaagat
    20101 ataaaaattt tcactagtgt tgcattaaaa ttttaaccta ttccatagaa caaaaaatcc
    20161 tttatactag cacttggatg acttatccaa gaccaataaa aaggactcat acatggataa
    20221 gtataaaaca aatacagcat ttaataaatg gttttctgcc ataaaattag gaaaactttc
    20281 tgtcaactcc caaaaatgta tttttgatta caattcgtat cgtaaaaaac tgtcttttga
    20341 agctgtgctc aagctctttc tctacgcagt taatgaagaa aaagaaagtt tgcgtgattt
    20401 gagtacagct cttatcgacc gatcgctcca actagaaacc gatgtgtcat cgattagtca
    20461 tacccaattg tctcgagcat ttaatgcact tgaacctaaa gtgttagaag aaatttttca
    20521 acaactgtta gaaaaagttc aacatcaaat caaaccaacc aagcgaaatc atctgtatct
    20581 gattgattcc agtacgtttt cgcttagttt aaaacgtcat aagtgggcga ctttccgtca
    20641 aacaaaatca ggtgtcaagt tacacttaaa ctattgttat atggacgata ctacgatgta
    20701 tccaactgat tttaccttaa caaatgccca tgaacatgat ctcaatcaac taccagtatt
    20761 ggtgaatcaa ccagaggcaa cttacgtgtt tgatcgtggg tattaggact ttgaaaagat
    20821 ggatcagatg cattgggatg gctatttctt cgtcactcgg attaaaaaaa acaccaaagt
    20881 tcacgtgata gatactctgg aaacatcgcc agaaacagaa attctacgag acgagctggt
    20941 tcgtttagga tctaaaacct atctaaccgc caatttccga ctagtcactg ttcaagataa
    21001 gaacggacgt gtgtttcaat ttatcaccaa tcgaatggac gtctcttcaa aagaaatctc
    21061 tgatatgtat cacgctcgtt ggcaaatcga attgtttttc aagcacatca aacaacacat
    21121 gaccattaaa accttctttt ctcaaagtga aaaaggcgtg cagaatcaat tgattttaac
    21181 gatgatttcc gctctcctca cgtttctcat caaattggag acgaaaacgg aaaaatcagt
    21241 gttccaaatc aaacgattct ttcgttattt actgtttcag ccctttgaat gttgtctaga
    21301 aaaattaatt cccacatgag aaaaaagaaa tttggctcgt tacttttggt tttcagttga
    21361 ataacagata aaaaattttc tggaaaaagt catcctctgc gtcagcacag ttttttttga
    21421 cttattttca gaggaaatag ttttcagaat attctaaaat gttttatgca acactagtga
    21481 tattttttag aattagattt ctaatgtgca ttttttgagt attaaggagc aagtatacaa
    21541 agatttataa agctgattaa atttgaataa aaatatgcag gaacgctact atttttagta
    21601 gtgttctttt ttatatttga ataaaaaatg tggtggttaa atggtggtta taacaaaaaa
    21661 tgaattaatg aaattaggtt atgggaagta tcagtctgag agaatcatac gacaggcaaa
    21721 agcaattatg gtttcaaaaa gctataccta ttacgaaaat agaagattag gactagtacc
    21781 tgttgaatct gtagaagaag ttttaggtat gaagatagag gtagaggagg attttcagaa
    21841 tcatggttaa ttttaaaaaa gataaaaatg ggaaatatca ttttactgct agtttgggat
    21901 tcgacaaacg aacagggaaa agagtacaaa aaaacgtaga ggggttaaaa cagttaaaga
    21961 agaaaaaaag cgtataccga acttgtttct aattatggaa aagaagcaga aacttctcaa
    22021 agtactatgt tgtttgagga gtttttttat aaattattcc taccttatta tcaagggaaa
    22081 gtagaagaaa gaacatataa aaatcggtta tctacaatca aaaaaacttt tcttatttct
    22141 ttaaaatgga gttaagagaa atacgtccaa ttgacattca aaagtggcaa aataatttat
    22201 tgagcaaata taaaaattct tatgtaagaa acatgtatgg gatttttcag atgtcattag
    22261 atcgagcagt tgttttggga ctacttgaaa aaaatcctgc aaaagttatt ggaaatgtga
    22321 agaaaaggaa aactacagtt gatttttgga caaaagaaga atttacaaaa gttatttcaa
    22381 ctttttatat tgatgatttg taccaacatt ttggttttat ttgtatgtgg ttacttttta
    22441 tgaccgttat gcgtttggga gaagccactg cattaacttg gaaagatatt gattttgaaa
    22501 ataaaaactt gcgtgtgaat aaaacactct attataagag agccaaaacc tatgagtttg
    22561 tagaacccga aacggcttct agtattcgta caatcgaact agacgacaat acaattacct
    22621 ttttaaaagc ttggaaggag cgtcaagttt caataggagg catgtcgttt gtactttctt
    22681 ataatggaac acctactcag aaatatacaa tccgtcatat tatgagaaga catgcaacga
    22741 tcgttggtgt tcatataatc cgcatacacg gattaaggca tagtcatgct tctttgctta
    22801 tatcacaata aaaagatgca cttcgaatta aagaaaggtt aaaacatgct gatgtacaaa
    22861 cgactttagg aacttatggt catttgtatc taaattcatt gagagagata acaaatgatc
    22921 ccacagatta tatccaaact aatttttcta aaatcaaacc gacacctatt tacgataata
    22981 aaaaataaat gataaacaaa agtaggatca caccaaaaga aacacactag aaaaactata
    23041 atacaggctt ttctagcgtg ttgtttctta tttccgccta tttatacatt atactcataa
    23101 agcatttaat gcatcgatcg tagccgcatt gtctatatgg gtatataaag ttgttgtatt
    23161 ggtacttgaa tgtcccaatt gttgggcagt taataccaat gaatttgtct gttggtagag
    23221 tctagtagct aatgtatgac gcagtttgtg agggctgact tgaattctaa agccttttga
    23281 atattttgct accatccgtt cgattgcaat accggatata cgcttggctt ctccttggta
    23341 aattgctaga aataaagctt tttcgttttc tgttacttta tatcgttctt tccgaatagc
    23401 tagataatta gctaaatatt ccattgcgaa tgctgctata ttgacagcat ctcttttatt
    23461 tccttttcta gttactacca cattattctt atctaaagat aggtcatcta aattaatatt
    23521 tataacctcg gagagtctca atccagatcc taaaatcagt gcattgatcg ccaggtctct
    23581 ttctacatct cgttgataat agatcaaagc tcgtttactc aaagtatttt tatattcatt
    23641 ggcaatataa tctagataat tttgtgtatc cttatctaga aataattttt tctcaatggc
    23701 attggcacgt gcagctaacg tagttttatc tgtgatggtt gctacttgat ccataggatt
    23761 attgtctaag tatggttttc ctagaggatt attggaactt ttcgaaagat atttaaatag
    23821 aacctttaat gccgtgatat ttctattgat agtagaagta gatagaccta agttattatt
    23881 atctttgagc ttagtttttg ttgtctcttt ttttacattt tcttttgtgc gacgtttcaa
    23941 atgagatttg tacaagttta ggtcataggc agttaactgt cttatcgagg tgatagaagt
    24001 atcaggaacg atagactcac tcagaagcca ttcataaaag agcttataat tttttagata
    24061 ttctaaagtg gttcgaggtg attgatcttt atcctcacga tcttgaacaa aatcttttat
    24121 ataatcgggc atatgaagta tgattgtatc tattttttga tatatttctg tatttttcat
    24181 gtcattcatc ctttcaataa gtaggggaga agagtatctc tataattgga ctataccaat
    24241 tatagaatgt tttgtcaatt ggtatgctct aaaatttatt aatttgtttc aaaaaaagca
    24301 tataaacagg tatacgttta ataatttaaa ataaatggta tacataaata gggaaggaaa
    24361 tagaagggag caatctaaat tttttgaatt ttcttaatta attatataga aagaacaatc
    24421 tttctataga gttagacatg agagggacta tgcttgattt aaaatcaaca agcgtatata
    24481 ctgtatatac aaagaaaaag gagggagaag actatggcaa ttaaagaaag aaaatttagg
    24541 gaagtgggga actcagtagt attaactatt tcaaaggagt ttcttaaaga aaatgggtta
    24601 aatcccggag atacggtttt tttagatgaa gaaaaacttc gagcggcaat tacaaaaaaa
    24661 caagccttat ctgatgaaat tgatttagca atatctcaag cattaactga atatgatact
    24721 acttttagag agcttgtcga taaatgagta ttcattacct agaagccaaa gatattataa
    24781 aaatgaatgt aatccaaata aaaaaatact ctcctaatga accccttggt gtaaaggatg
    24841 cgaatgcttt agaaatgtgt gtagggcaac ttcgagcctc agcttttggt gaagaggttt
    24901 atccttcgat ttatgaaaaa gcagctatcc tacttataca attgataaag aaacatcctt
    24961 ttcacaatgc aaataaacgt actgctttct tagctacttt tgtctttttg aaaatcaatg
    25021 gacagctttt agctattgat caaaaagatg ctgtaaattt agcggtatat attgctacgt
    25081 atgataagga tttcgatcaa ctaaaatatg aagtgatcaa cactataaag acacatacgc
    25141 agcccattta aggagttact gtatgtgtct ttatagggtt attagctgct atagcgaaat
    25201 aattgaagta aattacaaat agctataatt caaatccaac tatatagaaa acgtaaattt
    25261 tctatatagt tggattaaga taacgactat ttattttatc atatttttac tataccctat
    25321 acttttactt ggtatattta tgaataatcg caaatttacc cctatactac tagtttgtaa
    25381 gttagattaa taaaaatact aaagttattt gttcttttat taaatacacc tacaacttat
    25441 aaattgatgg tatttagata acacgaaaga ataaaaataa cagctgatag taaagtttgt
    25501 tgacgattgc tactcaatcg aaagtgagtt agtgcgtatg aacttgcttc tgaaaactta
    25561 tgaaatgaaa gaccttttac atcttgcaga aatcgttact gggattaaac taagcaataa
    25621 aaactaatgt tcccctcatt ctttgaactt ctactatttg atttatttat tctgataaat
    25681 gacgatttca ccttcaggat cttcaaatcc cgtatagaat ttatttaaga tctcttcagt
    25741 atcagtaata ggataggcga taggccacat accctttgat ggttagaata aactgctcaa
    25801 aatctgtatc gtatgttggc tttagcatat taacaaaggc tatctccaaa ttataaacca
    25861 taagcgttga atcgttctta acaatttcaa ttcttcctaa cccaaagtca gaagatataa
    25921 ttaccggact tgccttaccc ttcatgtggg ttgttgagat tccatattta aagggaattg
    25981 tcggtactat cggcggtctg aaaaacatcc caaaaataaa aaaatctttc ccctgctagt
    26041 ctcctaagtc cctttgtagc ggatatggca ccataatctc attttatcga agtgagtcat
    26101 ggtttatctg ttggccaacc aaaattgata caatctaacg atgcaccctc tacggcattc
    26161 taggggagtg cacttgcatt cacccaataa aaaccggcag ttagcaaaga acttatgtag
    26221 tcgtatgttc ttactgttaa catacaagag gtctcctttc cacaattgct tagcagtaaa
    26281 cgggaattta caaagctaat ctcttccatt ttcttatctt tgttctaaaa gtcccaaatg
    26341 gagcaactgt atttacatga ataaatttat atacttccca tacagccgtt ttggttgcct
    26401 cgtctgccca ttttcttttg tgtgcagtga atagatcttc atcactcatt gaatcaatca
    26461 tcatgttaat atcatcaata ttacgattga gaatttcctc taattctttc aatggtagat
    26521 gtgcataggt atttgtaaac cacttatata actctcctaa ctgattccat ttaaattgat
    26581 cagaaggcgt tttaacagat aatccatttc tttcatcatt ttcccatttt agaattaaat
    26641 tcgtccaacc aacttgatat gctaaatttt cagcaggtgt tctatccact tcctcaactc
    26701 ttttatcctt caattcttca ggaatagttt caaattctaa aatatattta gtataagtcc
    26761 tatttatttc tttttttaat tcttctttat ttttatatgt tctcattata ttacctccat
    26821 aaattcctaa ttgtctcctt taattcatct ataatttcat ccacgatatt ttaatccgtt
    26881 ctacaatgca tatctgatat gcattgactg tctaactcat atgtgaatga tttataaaat
    26941 atcccaacgt ctcatctaaa gaaatgttga tcgtcagcaa ggagctaaaa aatacgaata
    27001 tatttctttt gtagtaaaat cggactggtt tgcatatcat tttcttcgta aatatcaaaa
    27061 tcatgttaac tactatcaat tactaataaa aactaccact ttaagcgtta agaactgtta
    27121 agtttagtta agtgaggata gttcacaaaa tccattgtta aacttcacga aagtggtaaa
    27181 actcaaaatg ctttatatag gattacagca tcgctctttc ttcgattgcg cgttgggtaa
    27241 aaaatattat gaagtaaaaa ttgacgatga cacgttcctt acggctcatc agatgaaaca
    27301 gctacaaaaa cgaaatgatc aactcgaaga aaatttaatt ctaaaaaagc gattgccata
    27361 ttcacgcctc gctcgacgaa ctattaaagg tcaagattta cctgaagatc atccttttta
    27421 ggaaattgaa gctttttatg ttgcacaatg catttataat actacaatga tgttttcacc
    27481 agatattctt ctagggtgcg gtgtaatgaa acagatacac ttgcaaaaga aaattcaccg
    27541 cgaatttact aaaattatga ataattatgt taatcttccg aaattttttt ccaaaattaa
    27601 gggatcaagc tggtgttata gattgtttaa ggttggcaaa aaaataactt ctttttaaac
    27661 aattatagaa aaccgatact ctgttaagtt ggttgacacg gtgtcgattt ttatgacttt
    27721 cttattctga aacttcacta acggacagta cctaaaaagt ctatagtatg gacgtttacg
    27781 agtactattt tatcaaaaat gctgctcatt tcaacttata tgttttagtg aactaccccc
    27841 acttagcttg gataggctac aattaactag acagaaaaat taaggtgtgt agactagaag
    27901 aaaacatacc aggaggaatt tttatgtcta agagaacacg aagaactttt tcacaagaat
    27961 tcaagcaaca aatcgtcaat ctttacttag ctggaaagcc acgtgtagaa atcattcgag
    28021 aatatgaact aacggcttca gcatttgaca aatgggtaaa gcaatctaaa acgagt
//
LOCUS       DADLIO010000032        27672 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.032, whole genome shotgun sequence.
ACCESSION   DADLIO010000032 DADLIO010000000
VERSION     DADLIO010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27672
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.032"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(104..1336)
                     /locus_tag="JOX41_001519"
     CDS             complement(104..1336)
                     /locus_tag="JOX41_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAY6449267.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1591..2160
                     /locus_tag="JOX41_001520"
     CDS             1591..2160
                     /locus_tag="JOX41_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAY6449268.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2338..2778)
                     /locus_tag="JOX41_001521"
     CDS             complement(2338..2778)
                     /locus_tag="JOX41_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HAY6449269.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            2936..3700
                     /gene="map"
                     /locus_tag="JOX41_001522"
     CDS             2936..3700
                     /gene="map"
                     /locus_tag="JOX41_001522"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HAY6449270.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3732..4655
                     /locus_tag="JOX41_001523"
     CDS             3732..4655
                     /locus_tag="JOX41_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HAY6449271.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            4731..5870
                     /locus_tag="JOX41_001524"
     CDS             4731..5870
                     /locus_tag="JOX41_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HAY6449272.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            5863..6663
                     /locus_tag="JOX41_001525"
     CDS             5863..6663
                     /locus_tag="JOX41_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAY6449273.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            6663..7490
                     /locus_tag="JOX41_001526"
     CDS             6663..7490
                     /locus_tag="JOX41_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAY6449274.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            7468..8202
                     /locus_tag="JOX41_001527"
     CDS             7468..8202
                     /locus_tag="JOX41_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAY6449275.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            8302..9168
                     /gene="rfbA"
                     /locus_tag="JOX41_001528"
     CDS             8302..9168
                     /gene="rfbA"
                     /locus_tag="JOX41_001528"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HAY6449276.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            9182..9754
                     /gene="rfbC"
                     /locus_tag="JOX41_001529"
     CDS             9182..9754
                     /gene="rfbC"
                     /locus_tag="JOX41_001529"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HAY6449277.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            9776..10804
                     /gene="rfbB"
                     /locus_tag="JOX41_001530"
     CDS             9776..10804
                     /gene="rfbB"
                     /locus_tag="JOX41_001530"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HAY6449278.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            10902..11753
                     /gene="rfbD"
                     /locus_tag="JOX41_001531"
     CDS             10902..11753
                     /gene="rfbD"
                     /locus_tag="JOX41_001531"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HAY6449279.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            11787..13820
                     /locus_tag="JOX41_001532"
     CDS             11787..13820
                     /locus_tag="JOX41_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449280.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            13864..15144
                     /locus_tag="JOX41_001533"
     CDS             13864..15144
                     /locus_tag="JOX41_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HAY6449281.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNIIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            15354..16160
                     /locus_tag="JOX41_001534"
     CDS             15354..16160
                     /locus_tag="JOX41_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAY6449282.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            16172..17392
                     /locus_tag="JOX41_001535"
     CDS             16172..17392
                     /locus_tag="JOX41_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6449283.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            17382..18968
                     /locus_tag="JOX41_001536"
     CDS             17382..18968
                     /locus_tag="JOX41_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAY6449284.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            19007..21145
                     /locus_tag="JOX41_001537"
     CDS             19007..21145
                     /locus_tag="JOX41_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAY6449285.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(21513..22496)
                     /locus_tag="JOX41_001538"
     CDS             complement(21513..22496)
                     /locus_tag="JOX41_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HAY6449286.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            22874..24265
                     /locus_tag="JOX41_001539"
     CDS             22874..24265
                     /locus_tag="JOX41_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAY6449287.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            24281..25321
                     /locus_tag="JOX41_001540"
     CDS             24281..25321
                     /locus_tag="JOX41_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAY6449288.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            25340..26425
                     /locus_tag="JOX41_001541"
     CDS             25340..26425
                     /locus_tag="JOX41_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HAY6449289.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            26458..27420
                     /locus_tag="JOX41_001542"
     CDS             26458..27420
                     /locus_tag="JOX41_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-1,6-N-acetylglucosaminyltransferase"
                     /protein_id="HAY6449290.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSSVEFIRGIDLDQIKHKEFYYKHIDVYQKHDYPRINRNNTTAFKIFR
                     AIINRCLRMIKLPPKIRHHKFDLYHGSQWWALSKECLTELIQMYEQNQQDYLNFKIGM
                     FAPDEKFFHTLFFNSSFKNKNVIGGPDLPLELKNIEETTLQTSKLANIHIIDPSMNKW
                     FDERDIDQIKESEKLFVRKVKSDYSDKLLNRIDKEILKVGNIDE"
     gene            27413..>27672
                     /locus_tag="JOX41_001543"
     CDS             27413..>27672
                     /locus_tag="JOX41_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase domain-containing protein"
                     /protein_id="HAY6449291.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIIN"
BASE COUNT         8929 a         4549 c         5577 g         8617 t
ORIGIN      
        1 aaaaaacggt ggggttgttt agcgaaataa aggatctaag ccaatagctt agatccttta
       61 ttctatgctt tatattattt tttgcatgtg tgcgaaagta tactcaagcc caatcgccat
      121 ttcggaaaat cggtactgta gagccatctt cacggattcc gtcgatatcc atcttgtcag
      181 atcctaccat gaaatctacg tgggtttgac ttctattcaa tccagcttct gctaattctt
      241 catcggacat ttctgtaccg cctttcacac tgaaggcata agcagaacct agtgctaagt
      301 gattcgatgc gttttcatca aataatgtat tgaaaaagat gatgccagat tgagaaatag
      361 gtgaagggtc aggtacaagt gcgacttctc ctaaacgacg cgcaccttca tctgtatcaa
      421 gcagttttgc taagacatct tctccttgtt cggcagaaaa atcaacaact tttccatctt
      481 taaaagtaaa tttcataccc gagatgatgg tgccagcata actcagtggc tttgtacttg
      541 aaatgtaacc atctactcga tgactgtcag gtgctgtgaa cacttcttcc gtcggcatat
      601 ttgccatgaa tttttctcca cgagcattat agcttccagc gccttcccaa agatggtttt
      661 taggcaatcc gataatgata tctgtaccgg gagcagtata gtgaagggca gaaaattgtt
      721 ctcgattcaa ttcttctgct ttttttgcta atttttcatc atgcttcttc catgctaaga
      781 cagggtcttc ttcatagaca cgagtcgttt tgaaaatctg atcccataat gcctcaactt
      841 gtttttcttc tggcagttct gggaagactt ttgctgccca ttgtttacca gccgcagcca
      901 cgacagtcca actgacttta tttgcttgag ttgccttgcg taaattcatt agtgctttgc
      961 cattcgctga ttgataagac gctactcgat ggctatctac accagcaaat gcatcgggat
     1021 cggcagaaac aacgctgatc ctgcttgctc ctttttcaag ccattcatcc gcttgatcga
     1081 ttttagattg tggtacattc tcaatacgat ccgttgcagc atgtaaaaga aattctcttt
     1141 ggatctggtc gtcagtccat tgaacgataa cctcagcggc tcctagttta taagcttctt
     1201 gtgtgatcaa tcgagcaagg ggtgcctgtt ccacgctgat ctgtaaaaca actgtgtgtc
     1261 ctttttctgt ggctacgcca gtttctgcaa ttaagcgtgc atattttttt agaagttcat
     1321 taaaatcaga taacataata aaaattcctc ctcaccattt tttctggtaa ctattagcat
     1381 gataccattt aattatgatt caaacaatga ggctttaaat aaaaaaagga ggttattttt
     1441 ttaaggttaa gtttcatgat atatgttact acttgctatt tcagcttgtg aagaaaatca
     1501 aaaactaatt ttgcatatca aaaaaaacat gttacaatga aattaatcaa tggtggaagc
     1561 gttataaaaa aattaaggag attaaaaaat atggcaagaa aaaagacgat tactagagaa
     1621 cagattttgg cagctgctta tgaagtagct gccaccgatg gatttacacg atttactgcg
     1681 agaaacatcg cgaacaaaat gaattgttcc acgcaaccga tttatcttga gtttaaaaat
     1741 atggatgact tgagacaagc tctttttgag cagatctatg atcatttaca atatgaagtg
     1801 ttcactgttg agcatacagg gaatacgatt atcgatcttg cttttaatta tatccatttt
     1861 gcaagaagag agaagaagtt gtatcgttca ctgtacttag aagaatatgg tggaggaaaa
     1921 gagatgcaga atttctctta tacttacttt gtgaatacag tgaaacgcga tccagcttat
     1981 gtgaatcttt cagaagagca gatcgaatct ttgtataatg ggacatggat catagctact
     2041 gggatcgcag ctttgatgtc ttcaagcatc atccatccaa ctgatgaaca gattgaaaag
     2101 atgatccaag acagtataga tgctatcttg aaattcaaag aaccaatcga aatcgattga
     2161 atatactcaa aagttccaca aatcagtagg taacaagaga tgtgtcaaaa taaggaaaag
     2221 ttcgtttttc ttacagcgta tgcattttta actcccgaag aactcttcca tgaatgcaat
     2281 gaataaaaga gccatacaga ttgaataaat ctggatggct cttttattgc aagtatatta
     2341 aatttttgcg actagttctt tagcgaaagc ttctaaattt tcgatatctt cttcttcagc
     2401 attcagatcc actttaacat tttcggctcc ttttgatgcg cctgtttttg caaaagcagc
     2461 atcgaaatca tccaccgatt tgcagaattc atcgtaaaaa gtatcaccag atccgcagac
     2521 accgtaaatt tttcccaata gatccaattc ttgcaagtct tcataaaagt ctacgatctc
     2581 atcaggcaga tcgccatcat cgtatgtata agtagctact acgcaaatat ctgcctcctc
     2641 gaattcatct gcatctactt gggtacattc gttgatttcg acttcgatat ccagattttc
     2701 aaatgcttct gcaacaatat cggcgatttc ttcagtgttt cctgtcatgc tagcatatac
     2761 gatttttgct aaagccatga tgtgcctcct cgtttataat tatttaacaa ttatgaatta
     2821 taccaaaaca tcattgaaaa gaaaataaaa cctagagaca cctggggaat gtcatttggc
     2881 taaatgtatg ccgctatgtt aaaatgagag ggatttgtaa aaaggagacg aaaatatgat
     2941 tactttaaaa tcagcacgtg aaattgaaat gatggcagaa tctggagctt tattagcaga
     3001 tgtacataaa aatctgcgtg attttataaa accaggaatc acaagttggg atattgaggt
     3061 atttgtcaga aactatatcg agagtcatgg cggaattgct gcgcaaattg gctttgaagg
     3121 gtatgaatat gcgacttgta ttagtataaa tgatgaaatt tgtcatggat tccctcgtaa
     3181 aaagcctttg aaaaacggtg atttggtaaa agtcgatatg tgtatcgatt tgaaaggcgg
     3241 catttctgat tcttgttggg cctatgtagt tggagaatct acacctgaga tcgaccgatt
     3301 gatggaagta acgaagaaag ctttgtacat cggtattgag caagcacaag tagggaatcg
     3361 gattggtgac atcggtcatg ctatccaaac ttatgtagaa ggcgaaaatc tagcgatcgt
     3421 tcgtgatttt attggtcatg gcgttggtcc tacgattcat gaagaaccag cagttcctca
     3481 ttacggagaa gctggaaaag ggttgcggtt gaaagaaggc atggttatca cgatcgaacc
     3541 tatggttaat accggaactt ggaaaatgaa aatggatcct aacggctgga ctgcgtatac
     3601 aagagacggc ggactttctt gccaatatga acatacattg gctattacta aagatggtcc
     3661 aagaattttg acatcacaag gagaagaagg cacttattga tctatccagt caataggtac
     3721 gggagaggta catgaaagtt tggaacaaaa taaaacaaaa tgaaaatctg atgcgcttta
     3781 ttgagacgac tcaaaagcgc atcactgatt cagaaatgag tacgacctct gtcgtcgttg
     3841 cttattattt actcttgtct ttatttccat tgattattgc ttttggtaat attttaccgt
     3901 ttctccacat cgatcaagag actgtactga cctatttacg agaagtgatt cctgagaccg
     3961 tttaccagtt tatcggtcct gcaatcaaag accttttgac acaaagttca ggaggcttgt
     4021 tatccgtttc tgcattagcg gctttatggt ctgcaagtca aagtatcaat gctttgcaaa
     4081 ttgcgatgaa taaagcgtat ggcgtagaaa atagaaaaaa ttttttgatc gtccgtttct
     4141 tctcactaat tgtcattgtc ttgttcatga ttgctattag tggggtaact atcgttcttg
     4201 ggttgggaca gctgattttg gatgctattc agccaatcgt acaaataccc gtgaacttta
     4261 tcgatcagtt ccaaactttg aagtggccaa tcacattggt agctttattt gtcatcatgt
     4321 tcttgattta tttaattgtc cctaatgctc agttgaagtt gaagacgatc attccgggca
     4381 cgatcttcgc tactgtcggc tggatgctgt tatcacaagt gtttagtatc tatgctaggt
     4441 attttgcaac gaggatcagc ggttatcaga tcataggaag ttttattgta ctcatgcttt
     4501 ggcttaattt tgctgctacg atcatcattt tgggcggaat catcaatgca gttgttcaag
     4561 aatacgtgac gggtcatcaa atcaaaaaac gtcgagatcc aagccgaaaa tggttcaata
     4621 aattgaaaac taaattttct cataaaaaaa agtagaaaca agagttctta ttgtaaattt
     4681 atatcagtaa tttataataa ttatgactct taattaaagt aggtgcccat atgcttgttt
     4741 cttttagtat ggttataaga ttttttctga caattttatt atcactgata ttaacacctg
     4801 tattcaaaat catttcagta caaacaggta tggtcgacaa accaaatgaa agaagaataa
     4861 ataaagttcc aatgccttca gcgggcggac tgcctatctt tatttcattt gttatatcga
     4921 ctttattctt attccgtaaa attatccctc aatcgtatat tgtaccgatc ttgattgctt
     4981 ctttagtaat catagtcaca ggagtgctcg atgataaata tgagctgaca cctaaacaaa
     5041 aaagtatagg gatcttgatt gcttctctta ttatttattt tgtagcagat atacgtattg
     5101 attccttcac gcttcctttt attggatata tccaactagg ctggcttagt tttcccgtaa
     5161 cgattttttg gatcttcggt atcacgaatg cggtcaatct gattgacggt ttggatgggc
     5221 tggcggcagg gatttcattg atcggtttaa ttacgatagg aatcattgga tattttttcc
     5281 tccatgcttc tacagtgtat attccagttg ttattttctg tcttgtagca agtattatcg
     5341 gtttttttcc ttacaatttt tatccggcaa agatttattt aggcgataca ggagctctat
     5401 tcctagggtt tatgatggcc gtcctttcac tacaagggct gaagaacgtg acttttgttt
     5461 catcgatttc tttgctgatc gtcatgggag tgccggtaac agacacgttt tttgctatca
     5521 ttaggagaaa agcaaaccgt gtttcttttt ctacagcaga taaaaaacat cttcatcacc
     5581 gactaatcag tttaggcttt actcataaag gtgctgtcct gacgatttat gcgatggctt
     5641 tgatgttttc tttcacagct atggtcatga attatactgg aagaatcgga acgatcatat
     5701 tgattattgc catgttgttt gctgcaattt tattatttga attgattggt ctgatcaatg
     5761 agaaacatca gtttatttta aaaacattgc gatttttagg gaataaagag taccgtacgc
     5821 aagtaaaaca gaaatatttg aagaaatgga accgtcatat agatgaataa caaattaaac
     5881 cagccgatcc ttattagtat tgtgacggca aacagtgata aaatttttcg gacactagat
     5941 aattttattt caactgtaaa agatgaaaca gcagtaaaaa tccgaatttt tgacaacaat
     6001 tcacttcccg agtacaaaaa aagactaaca gagtatagga aatatcccta catcgatatc
     6061 tattttcatg atgaaaattc cggatttggt tatggacata atcacaatct gatagctagc
     6121 gattctcgct atggcattat ttgtaaccca gatattttag tggatgaaga gacagttaca
     6181 gcattggtct tgttattgaa agaacatccg gaatgtgcga tgttagcacc taagattctt
     6241 aatgaagatg gaacaactca gcacctcatc cgtgagcagc tggctgtttt tgattacgtt
     6301 ttgcgctttg tgcctttcaa atgggtcaaa aaaaagtttg acaaacgact ggctgtgttt
     6361 gaatgccgag gattgcctac tgatgctaat agttatgtac ggatgatctc aggtagtttt
     6421 atggtagctg atattgataa atttaaagag ataaaggggt ttgatgagcg tttcttcatg
     6481 tactttgaag acaacgactt gtgtttgagt tttgaaaaag caggttacaa gttattgtac
     6541 acaccctttt atgcagttat ccatttttac gggaagggtg cgcatcgaaa tgcaaaactg
     6601 tttcgcgtgt ttttgacttc tatgatgaaa tttttcaata agtgggggtg gcgttttttc
     6661 tgatgaaacc agaaatatta gtagtcgttg tgctttatca gcaactattc agtcaatctc
     6721 cagcttatgg accattaagc aaagcactta gcgaaaagca aattcagctt attatttacg
     6781 ataatagtcc tcaaaggcag caaaatgagc tgtttgaaaa agaaaatatc gtttatcatc
     6841 atgatccgca aaatcctggt ttagcggtgg cttataattt tgcgttgtct caagcagatg
     6901 aaggaacacg ttgtctcgtc actctggatc aggatacgag gctagtcgac gattattttg
     6961 aactattgcg taaagtaacc tttacagatg aatgtgttgc tgcagttccg atgatttttt
     7021 ctgggagccg acaagtttct cccctatatt cagatcgtta tatcaatcgt acagctcaag
     7081 cagtagaagt tgaaggccca acagctgaac gaatcatggc aatcaattca ggtgttgcct
     7141 ggtctgtcaa atttctaaaa aagattggcg ggtttaatcc tgctttttct ttagattttt
     7201 tggatcattg gctgttttgg aaagtggatc agttggaaaa aactgtggag atccttcctg
     7261 tacgaatgga acatgatctt tcggttttag actatgaaaa agtttcaagt aatcgatacc
     7321 gttctatttt acaagcagaa aatcgatttt atcatgaata tgatcaaagg catttatcca
     7381 gtcaccgacg acaattattg ttaagaacag ctaaacagtt cttgaccgtc aaaaaccggc
     7441 atatctggcg gatgactttg cgctcatatg ttaagaattg gaaggtgtga attcgtgcgt
     7501 tcggtttgta tagctacctt taatggaggc agatatttaa gagagcagtt agatagtatt
     7561 ttatctcagc tttcagcaga agatgaagta gtcatttctg atgatgggtc agtagatgat
     7621 acatgggata tattaactga atacgcagaa aaagataagc gaatccagct tttttcgggg
     7681 cctcgtcaag gattgatcgc taattttggt tatgcgatcc agcagacgaa aggagatcta
     7741 atctttttgg cagaccaaga tgatgtttgg ttggagacaa aagtgaaaaa gatcactgac
     7801 tattttgagc agaatccgga tcagctagta gtagtttctg atttaatcat tgtggacagc
     7861 gagctgcaag agatccatga ttcgtatttt tcgtttcgaa attccaaaga aggatggctt
     7921 aataatgtga taagaagtca ctatattggt gctggtatgg ctttccggtc ttctttaaaa
     7981 cccgatattt tgccgatccc gtcagaagtg ccgatgcatg atatgtggat tggtttgctg
     8041 ggaggaaaga agactgggtt cctaagagaa ccgttaactc tgtaccgaag acatgattta
     8101 aacgcgagtg agattgaaac acattctaaa ttacggcaaa aaatttcttg gcgtgttcat
     8161 ctgattacgg cgttgatcaa acgaaaatgg tttaaacgtt gataaaagat gtttaaatcc
     8221 ttaatatttc catgacaaat ataacaattg atgagataat aacaaagtga aatttgaaat
     8281 caaaaaggag agcagatatc catgaaggga atcattcttg ctgggggcag cggaacacgt
     8341 ctgtaccctt taacaaaggc aacatcgaaa caattgatgc cgatttatga caaaccaatg
     8401 atttattatc caatgtctac tctgatgttg gcgggaatca aagaaattct gattatttca
     8461 acgccacaag atacaccacg tttcaaggaa ttatttggaa acggaaatga tttaggactg
     8521 cagatcgaat atgcagtaca agaaagtcca gatggattgg cacaagcgtt tatcattgga
     8581 gaagaattta ttggagatga tagtgtctgc ttggtattag gggacaatat ttactatggt
     8641 ggcggtctgt ctaaaatgtt gcaacgagca gcttcaaaag atacaggcgc gacagtattt
     8701 ggctatcatg tcaatgatcc agaacgcttt ggtgtagtag aatttgatga gaatatgcaa
     8761 gctttgtcga ttgaagaaaa gcctgctcag ccaaaatcaa attacgctgt aactggcctt
     8821 tatttttatg acaatgaggt aatttctatc gctaaaggta tcaaaccttc agaacgtgga
     8881 gaactagaga ttacggatgt caataaagca tatttggata aaggaaaact atccgtagaa
     8941 cttatgggac gcggatttgc ttggcttgat acaggaacac atgaatcatt gcttgaagca
     9001 tctaccttta tcgaaacaat tgaaaaacgt cagaacttaa aagtggcttg tttggaagaa
     9061 attgcttacc gtatgggcta catcgataag gaacaattgc tggcccttgc acagccattg
     9121 aaaaaaaatc aatacggtca atatttattg aatttggccg ctgaataagg agtccttaca
     9181 gatgaaagta acagatacaa aattaacaga tgtcaaaatc gtagaaatgg acgtctttgg
     9241 cgatcatcgc ggtttcttca cagaaagtta ttcaaaagca aaatttgcag aacatggatt
     9301 gaaatatgac tttgttcaag acaaccattc actatcagct gaagctggtg tccttcgggg
     9361 gcttcatttc caaaaaggag aagctgcaca gacaaaattg attcgggtag tcactggagc
     9421 agttttagat gtagtagtgg atatccgcaa aggtagcccg acttatggtc aatgggacgg
     9481 atttatctta tctgaacata atcatcgaca gttgcttgta cctaaaggat atgcccatgg
     9541 attcgttact ttgacaccaa atgtgaactt cctttataag tgtgataatt actataatgc
     9601 agaagcagat gggggcatcg catttgatga tccagattta gcgattgatt ggccaattga
     9661 tccatcaaga gcgattatgt cggaaaaaga tcaccgtcat ccgacattaa aagaatttga
     9721 agcagaaaat ccatttgttt acggagaaat ctaagaatta aggagaaatt ttcttatgaa
     9781 aaacatcatt gttaccggag gtgccggatt catcggctct aatttcgttc attacgtggt
     9841 aaacaatcat ccagaagtgc atgtcactgt tttggataaa ctgacttatg caggaaacaa
     9901 agagaacttg gctggacttc ctagcgatcg cgtagaattg gtcgtaggag atgttgcaga
     9961 tgcagaatta gtggaccgtc tagtaaaaga agcggacgca gttgttcatt acgcggcaga
    10021 atcccataac gataattcat taaaagatcc tttcccattt gtacaaacga atatcattgg
    10081 tacgtataca cttttagaag cttgccgcaa gtatgatgta cgctatcatc acgtatctac
    10141 tgacgaggtt tacggcgatc ttccattacg tgaagacctg ccaggacatg gggaaggcga
    10201 aggagaaaaa ttcactgcgg aaacaccata taatccttca agtccatatt cttctacaaa
    10261 agctggttca gatctgttag taaaagcatg ggtgcgttct tttggcttac gtgcaaccat
    10321 ttcaaactgt tcaaacaact atggtcctta tcagcatatt gaaaaattta ttcctcgcca
    10381 agtaacgaat atcttaagcg gtattcgtcc aaaattatat ggcgaaggaa agaatgttcg
    10441 tgactggatc catacgaatg atcattcttc agcagtgtgg ctgattttga cgaaaggcag
    10501 aattggcgaa acctatctga tcggtgcaga cggtgaagaa gataataaga ccgtgatgga
    10561 attgatctta gaaatgatgg gtcaaccaaa agatgcgtac gaccatgtaa acgaccgtgc
    10621 aggacacgac ttgcgttatg caatcgattc gacaaaatta cgggaagagt taggatggaa
    10681 gcctgagttt acgaacttcc gtgatgggtt ggctgacacg atcaaatggt acgaagaaca
    10741 tgaagactgg tggaaaaaag aaaaagaggc cgttgaagca gcatatgcca aaaatggaca
    10801 ataatacaga gaaaatgtca ctgtattaat ggaaaaacac atgtgaggca ggcgctcgcc
    10861 tgtctctttt ttaaaataaa aatcaaggag cggataatca tatgttttta ttaactggag
    10921 gaaatgggca actaggtaca gaattgcgcc atttattaga tgaaaaaaat ctgcaatatg
    10981 tttcaacaga tgcaaaagac ttggatatca cagatgccga gaaaacaatg gcttacatca
    11041 cagaattaaa acctgatgtt attttccatt gtgcagctta cacagcagta gataaagcag
    11101 aagaagaagc aaaagaatta gatgagaaga tcaatgttga tggtacaaga aatgtagcac
    11161 ttgcagcaaa agctgtgaat gctcaattcg tctatatcag tacagactat gttttcgatg
    11221 gaaaaaacaa aaatgtagaa tacgaagtag acgaccaaac gaatccacta aatgaatatg
    11281 gtcgtacgaa attattaggc gaaaaagcag tagaagagat tttagaagac tattatatca
    11341 tacgaacttc ttgggttttc gggatctatg gacacaattt cgtcttcacg atgcaacgcc
    11401 tagcggaaac ccgcgacaaa ctgactgtag taaatgacca gtttgggcga ccaacttgga
    11461 cacgtacttt ggcagaattt atggtatatg tcatcgaaga aaaagcacca tttggtattt
    11521 atcatttgtc gaacgaaaat agctgttctt ggtatgaatt cgcaaaagaa atattgaaag
    11581 atacagatgt agaagttgca cctgttacgt cagaagaatt tccgcaaaaa gcaacacgtc
    11641 cgcagtattc agtcatgagc ctgaaaaaga cagaagagtt aggatttgtc ataccaactt
    11701 ggcaagaagc acttgcgcaa atgctggaag ctgccaaaaa aatgaataag taatttcctt
    11761 ttatcaaata gaatttggag catgatatgg aaaaacaaac aagaagtgca cgacgaaaag
    11821 aaaagccaaa agcgaaccag gcagattcga atttggtgct tgacctgttt ctaaaactcc
    11881 gctatcttat tggcgtttta gtcatcgtgg tcatcgttac ttttaattta aacggaagtt
    11941 cacttggtgt ttgggataaa tatgtgtcgc aaagagacga tgggaaaaaa actgatgtga
    12001 tttttggaca gaatcgggaa gtgcggtcag acgaatggct ggtgcagaca cctttttacc
    12061 tctcacaagc tgaagaggac tttccgttgg tgaacgagga ttattcatta aacggacaaa
    12121 acatgatcat tgcgtataat tctcctgtaa aggatattac ggttatcgga aaaccattca
    12181 actggggatt ctttttcctc ggaagagatc gaggactttc cttttattgg gcgatgaaat
    12241 tagtcgtcat ggtcttgctt ggattcgaag tactgatgat attaacgaag agaaaaaaag
    12301 ctctatcgct aatcggtgca tttgcgctga cattttctcc agcagtccag tggtggttca
    12361 tgcaacatgt gggcgatttg attttcttta ctttgggact gatgactgct ttttatcatt
    12421 atttctacaa tcatgataaa aaatggctac gaacgttgat gatgcttttg gtggttattt
    12481 tcggtattgg gtttatttta gtgatttacc cagcccatca agtgatgctg gcgtacttgc
    12541 tgatttttta ttttgttggc ctgcttattt actatagcaa gaaagtttca tgggatctgt
    12601 tggatgtagt gttgattgga ggggcagttt tatttattgg cggagtcatg gttcatttct
    12661 ggctaacgtc aaaagacgca ttgttagctt ctttgaatac cttatatcca ggaaaacggg
    12721 taagtactgg aggaaagtgg acgattggcg aatttttttc tttccttaca aattggaaaa
    12781 ttccttttga agatatcaac tattcgaata actctgaagt ggccctgttc tatcactttt
    12841 ttccaactgt attcctagca agtccatttg tgttatttgg caaaaaagat agcgaacaaa
    12901 agttactggg acgtattttg atgatttttt gtctgttttc tatcttttgg attaccgttg
    12961 ggttgccaaa atggctagca gaaatcactc tgctgtctta tgttcctcca ttaagagcca
    13021 tccttacttt tagttttgcg gcttgtttat tatcgatctg gtttatcgct tatatttgga
    13081 gagaagatgt tattcctatt tggtataaat tcattttgtt ggcagtaaat gcatggtctt
    13141 atttctatgc gattacgcat tcgaaaatgg ataattattt ttcggatttt gaaaccatcg
    13201 cagttgctgt gttgggaaca gtgattttag cttttgcatt atttggctgg agacgcttgt
    13261 tttacctcgc ttttgccgcc ttagttatcg tatctggctt tttcgtcaat ccagtcgtag
    13321 aaggtacagg agcgattttt gaaaaaacac tggcaaaaga aatccaaaaa atcgatcaac
    13381 aagatcctgg taaagtttgg ttgtctgaag atgaattata taacttcacc ccaacattgg
    13441 gagtgaaatc cttcaataca gtacgctttt atccagatat agctgcatgg aagaaaatcg
    13501 atccgaaaga agaatacgag aagtattata atcggtatgc tcatacaaga gcttttatcg
    13561 ctaaggaaga tacaaagttc attttagatc gtccagatat gttttcggtc acgttgaatt
    13621 ttgaagacgc agaaaaatta gggatcgact atgtgatcag taaacgacca ttaactgatt
    13681 acaaccaatt atatgaagcg cagttcacgc agctatatgg accggataaa gacggttata
    13741 tgatttttaa agtagaatat ccggattatc cagatgtacc acaaacacaa actcaggaaa
    13801 atcagctagt cgtacagtaa taggctagct gagaataatc ctgaaatgtt agtagaaagg
    13861 agagtggaga taattcaagc aatcgtacaa aaatttgtca acaaaatgag tgtcggtttc
    13921 ttgcttttgt tactgacgct agtctttttt gtttggacag cagggttagg ttttccagca
    13981 actttgttta tatataacaa tagttcatta cttatcgctt ttagtgtggc tattttgctc
    14041 attttaaatg tttataaagc aaaaggcgtc gattttcttt atctaggtgt tgcgcttgcc
    14101 cttttcattt tcttttctta ctttcgggaa ttaagaaatg agtctttatt tggagactta
    14161 ctgtttcctt tgattatttt attttgttta gtaattaaat ggatcgagtg gacaaaatgg
    14221 gatcgcggta tttatctgat tgtcttttcg gtcttcctcg gaatcacgtt atatcgtgta
    14281 tttacagaga tccaagtacc agaaggacaa agcatctggg ctccaggcaa ttcgctttct
    14341 gatatttgga tcaatacgaa tataatcgga agttctttga tgactcttgc tttattgatc
    14401 agtggatttg ccagttcttt tgaacgatgg tatgtacgaa tcatcggtgc agtagcagtt
    14461 gttgcagctt ttctcgggat ttgggtctgc caatctagag gtgcattagt cgcgttgatt
    14521 gtttttgcga tattggatct tttacctaaa tcgttgatgc gtgtcattcg tgcgccattt
    14581 attgcttaca cggttacgat tcttttagct ttgccgattt cttatctggc ggctgtctct
    14641 gaaaaagtca atttgtttac cggtcgagaa gatatttggc ataaattcta tcagacgcta
    14701 ggagaaaaat ctgaacaaat tttactagga atgaaaacat ttatcttcca acgaggaaac
    14761 caatttttag gaaaccacaa tagttataat tctattttga atatctatgg attgatagga
    14821 tttgggattg ctgctttgct gcttatcctt tttattggtc gcttaacgtt gaaagcagat
    14881 ttatccaacg ggcagatgac ttttatctgg gccttttttg cggtgatgat gcagtcattt
    14941 atggaggata cattgacttc atacccatgg gttccgatta tttatatcct gttggctatg
    15001 gccgttcatc gatatgatga accagaagtt gcggaggaat tctatgttat ggaagaggca
    15061 tatgacgata tgacttatga tgatacatct tatgaggaac aaccagatag cgctcattct
    15121 tccaggatcc aacgctatca ttgataggca caaaatacga gagaggctgt gacaaccgtc
    15181 gcagcctttt ttggtttatt gcaattgtct agcatcttct gtaaaataga aacgttagag
    15241 aaaatcttgt atcatagaaa attaagaaag aaataagaac gcagctcggt accaaaaata
    15301 tggtaaaatg gcacttgact gtaattcact gaaaatcgct tggaggaaca caaatgttta
    15361 aagatttgta tttatttatg aaggacattt atcagaacag aaaattattg ctacagtttt
    15421 cgatcaatga cttcaaatca agatatgcag gatcgttttt aggaatctta tgggcgttta
    15481 tcaatccgct atttactgta ttgatttatt ggctggtatt tggtgttgga ctgaaagcac
    15541 aaatgatcga tgcaaaatac ccatttatcg tatatttagt taccgggatg attccctggt
    15601 tcttcttctc agatgcattt gcatcaacta cggttgtttt tcgggaatat acttatttag
    15661 taaagaaagt cgtattcaat attcgtatct tgcccacgac gaaaatccta tccaatctgt
    15721 acacccactt attcttcatt ctgattggca tagctgtcgc gcttataaat ggtatatatc
    15781 cttcagcaat gtctttacag ctgatttatt atttattttg catgtgtgct ttcttgacag
    15841 gattgacttg gctgacggca tcgatccaac catttttacc tgatatcatg caattaatta
    15901 cgatcgtgct gcagttgatc atgtggacat taccgatatt atggagccct aatcagtttg
    15961 attcaggtct tgtaagcata ttgaaattaa atccgctgta ctatgttgtt caaggttatc
    16021 gtgagtcatt tttaagtgaa gcttggttct gggagcatgg aacatatact ttgtatttct
    16081 gggttttcac gttagtaatg ttcgtaatcg gctctgcagt gttccgtaga ttgaaaccac
    16141 atttttcaga tgtgctgtaa ggagaatagc tatgacagaa tatgcaatta gactaaaaga
    16201 tatcacaaaa tcttataata tgtacgcaaa accttcggat cgatttcgtg aagccctcaa
    16261 tccttttaag aaatcctatc atgatgtatt ttatgcgttg aaaaacgtga atgtagaaat
    16321 aaaaaaaggt gagatgatcg gtttcgtggg agaaaacgga tcgggaaaat ctacaatgtt
    16381 gaaaatcatt acgggagtac tgacaccaac atccggcacg atggaaatcg aaggaaaaat
    16441 ctcagctttg ctagaactag gatcaggatt caatcctgag tattctggct atgaaaatat
    16501 ctatttaaat ggaatggttc taggattttc aagagaagaa gtcgatgaaa tggtcgatga
    16561 tatcattgaa tttgctgaca tcggagacca tatttatcaa cctgtaaaaa cttattcaag
    16621 cgggatgttc gttcgtctag cttttgctgt agcaatcaat gtgaatcccg atattttgat
    16681 tgtggatgaa gcattggcag taggcgatct tgaatttcaa ctaaaatgta tggaaaaatt
    16741 tacagaaatc aagaactcgg gaaagacgat tttattcgtt tctcatgata tcagttcgat
    16801 tcgtcgtttt tgtgatcgtt cctattggtt gaaaaacgga gaagtcgtcg aatatggcga
    16861 tacgatggaa gtaacgacga attatgaaaa ctttttaaag aaaaaatcag ttaaaacagt
    16921 ggatcggaat aaaaaccaag tagaacggtt cgccgctcca gatatcgtcg acgtgacgaa
    16981 agcggaattg ttggataaag acaaaaatcc ggtggatatg ctggaacaag gagaaaaact
    17041 atacgttaaa gtaacttatg aagtaaaaga tgatacaatc aaaaatccgg ttttaggaat
    17101 tgcgctacga acagtcgaca atttttatgt atgcggactt aatactctac tagatggtat
    17161 caagattcct tggaaaaaag gagagaatat cttttatctg gagtatgaaa agttaggttt
    17221 gttagctggt gaatattatt ttgacgttgc ggtctttgaa gaaaatgcaa cggttccttt
    17281 ggtatataag acaaagtaca tgaacttgtt tgtcagcggt tcttatatcg gagaaggcat
    17341 cgtggtctta gaccataaat gggaagaagg gactcatagc aatgaaatat gattttgaaa
    17401 tggacctaga tgaacaaagc agtgtgggaa aaattgccgc acagatcaaa ccaggaagta
    17461 aagttttaga gtttggtccc ggaaacggcc gattaacgaa acatttaatc ggagcaaaac
    17521 aatgtgaagt gagcattgtt gagttagata aggaattgtt cgattttgtc agcgaatttg
    17581 ctcaagatgg attttatggt gatatcgaaa gttttgagtg ggcaaactat tatgctggac
    17641 agacatttga ttacgtcttg tttgcggatg ttttagaaca tttggtagat cctggaaaaa
    17701 cattgaagaa agtcagagaa tttttgaatg aagaaggaga gatcctgatt acattcccta
    17761 acttggcgca taattctgtc atgatcgatt tgttcaataa ccaattgccg tgggcttctt
    17821 atggtctcct agatgaaacc cataattctt tttatactca tgatggcttc caaaaagttt
    17881 ttgaaaaagc gggattattc attaatattg aagattattt gtacttagct gtaggtgata
    17941 cagaattaaa atcaacttat gaagaattgc cggaagctgt acgctatgat ttcaaaatgc
    18001 gaccatttgg tgaagtctac caatactttt tctcattgat gaaacatcca gtagcacaaa
    18061 gttccattgc agagccacaa aattctaatt atgtaaaagt gttagaagta acccagcaaa
    18121 cgaaacaaga tgaaacaatc caacaaatac cattcaataa tttcacaggg gaaaatgaga
    18181 cactaagttt ccccgtatca gaaacaacag aaagaatggt gtttcgcttc gcgcaacaac
    18241 ctagctttat cgaattcagc gcagaagctg ccggagaaaa actaacattt atcgattcga
    18301 atgctgtagt caaaacagta aatgattgtt atttgtttga tgggaaagaa ttaccagagt
    18361 tcgttctaac ggatatttct gggaaagaag tgactatcca ttgtcactat cgctttatcg
    18421 gggaattgac accaacaatg aaagaattgt tggaaacgat tcgtcccatg gctgaagtca
    18481 caaagcagct ttctgagaaa aatgacgaat tagaaagaga aaatcatcat cttcttgagg
    18541 aaaatacaag actagaccat acgttaaaaa caaccacaaa tcgctattgc acattgttgg
    18601 aaagtgatga atggacaata aaacatagac taggacgacg taagaaagaa acttcgaaaa
    18661 aaatccaaga aaaagaactt tctatatgta ttgacgagaa aatctgggat gcagaaacaa
    18721 aaatattaaa aatcatcgga tggggaatcg ctaattcgga tcgccagccc ttgtcctata
    18781 agttatcagc tgaccaatcg ccatttttcg aagcaattcc tgtttcacga gaagaagtca
    18841 atcaagcaga acagctcgca aaaggaacag aagcgggatt tgagttacga atcctttgcg
    18901 agcaagaacg ttcattctta gtggaagcag tagctcaaaa tggccaatca tggatcattg
    18961 aaatgtaaat aatgattaac ttataaagat aaggagtaaa cgaatcgtgc aaaaaaaaga
    19021 aattgccgta tttatcgatc aaatcactcg tgaacgggcc actggcgatt tgcttattgt
    19081 gggctgggca attgatgaag tgaccaaaga aatccctacg ataaaggtag aaaaagaaaa
    19141 tgtgattgct gaagcaacac atgtcgtaag attggatatc aatcatttat ataatcttga
    19201 tgttaagacc caaagcggtt ttaaggtacg tttatcaggg aaaatgagag gaaaagccat
    19261 cttagacttc caaacagcga gacatcaaaa tggcatagct gtgaaattaa acggtaaata
    19321 cccttatgat gacggcattg aatcttcatg ggaaagaaaa aaaagattac tgaaaaaagg
    19381 gataaattat gcaaggactc atggcgtaaa aaaagcgatc cgtcgggtca aattggaatt
    19441 gaagccagga tcgatcgact atgcagagtg gatcagtcgt catgagaaac cagatttgaa
    19501 agagcaaagg aaagaagcac aaggatttgc gtaccgtcca ttgatttcca tacttatgcc
    19561 tgtctataac gttgaaatca aatggctcga aaaatgcatt gattcggtac tggatcaaac
    19621 gtatgatcat tgggaactat gtatcagtga tgatgcttct actgatccag ctatccgaaa
    19681 gtgtctggaa tcctatcaag caaaagatga tagaatcaaa gtcgttttcc gaaaagaaaa
    19741 tggacacatc agtctggcaa ctaattctgc attggaaata gcagaaggag aatttatagc
    19801 actcttagat aatgatgatg aattaccgcc atttgcatta tatgaagtgg caaaagtgct
    19861 aaacgtacat ccagaactgg atgtgatcta cagtgacgaa gataaaatcg atgcagatgg
    19921 caatcgcttt gatccgcatt tcaaagcaga ctggtcgcct gatacattga tgggaaataa
    19981 ttatatctct cacttaggcg tatatcgaac aagcattgtt aaagaacttg gcggtttccg
    20041 taaaggctat gaaggttctc aagattatga tttggtcctt cgtgtgacag aacaaatccc
    20101 tgcagatcat atttaccaca ttgaccgagt cttgtatcat tggcggacga tcccaggatc
    20161 aactgcaagt aatggcgaag ccaaaagtta tatctatgat tccggagtga aagcattgac
    20221 agatgccctg tctagaagaa acatcaaagg aagcgtacgt cctggcagaa tttctggatt
    20281 ttatgagatt gcttatgacg tcttgcaaga ggatttggtc agtgtgatca ttccaacgaa
    20341 gaatggctat gaagatctaa aaacttgtgt ggattcgatc atcgaaaaaa cgtcttattc
    20401 aaattatgaa atcattattg cggataacgg aagtacagat ccaaaaatgc aagaattatt
    20461 tgcagaatac aagcatcagc tgaaagaccg ctttatcgta gaattgattg acattccatt
    20521 caattattct cgaattaaca atttagcagc agaaaaagca aacggcaaat actttttatt
    20581 cttgaataac gatacagaag tgattgagcc agattggatg acggtgatgg tttcttatgc
    20641 acagtttgat cgaatcggct gtgtaggagc aaaactgttt tatccagatg atacaacgca
    20701 gcatgcagga gtattattag gaatcggtgg tgttgcaggg catgcattga ataactatga
    20761 tcgaacacat tgtggttatt tcggccgatt ggtcattgac gtcaattact tagcagtcac
    20821 tgcagcttgt atgatggtca aggcagctga cttcaatgct gttaacgggt ttgatgaaac
    20881 attagaagta gcattcaacg atgttgactt gtgcttgaaa gtttatgaac tgggtcgtta
    20941 caatgtctat gcacatcaag cagaattgta ccatttcgaa tctaaatcaa gaggttatga
    21001 agatactcca gaaaaacaaa gacgttttgc tggtgaaatc aaaaaaatgc aagataaatg
    21061 gccagcatat attgcgcatg atccatttta caatgataat ttaacaaaag aaggaatcgg
    21121 cgacttttcg ttgagaccag attaaactat aataaaaagc tgttatgttg tgattcgctc
    21181 gcacataacg gctttttata gttttttgtc aaaaaaaggc agaaggtgcc gactcaaaaa
    21241 aataagtcga ggttgggaca gaagtgttta actccgagaa ataagaagaa attcacgaaa
    21301 attgcttttc aaatttttgt gaatttcggc ttatttaaga agaagttgct tctgctccca
    21361 ccgtttattc gtttttaaag aatgagacaa aagtgtttct tacttttgtc ccacgctctt
    21421 attcatgctc agagcgccaa tagatacaaa atcatagcca aagtttcacg aaccctagct
    21481 gtcaaagaat cgatatttta ttttaatata ggctatttta aaataaatgg tttaaggtat
    21541 tcctctacaa aagccactct atcaattatc atgggtttaa aataagaagt gatggagata
    21601 accagattgt tcttagcgtc aatataaaga acatttccac tattaccaat tgctgaatat
    21661 atttcgttct cagaatctaa tacccaccat aaatagccat atctcatatt ttgtaagtct
    21721 tctaaagcac tggttctagg tttgaacatc tcgtttatcc acatgggtgg tacgatttgt
    21781 tttcctttat acatcccttt atttaggcat aatacaccaa tttttgccag atcacttgcc
    21841 gataaacaca aaccatatcc tgccgtcccg atatttagtg gatcacaaaa ccagacattg
    21901 gttttaggag acttatccat tgtaaactgc ttatgttctt cagctgtttc agcataataa
    21961 ttgacatggt ttggtatccc tataggatca aatagatact tattggcaaa atcaacagtt
    22021 gttagcttac ttgtctgata caacaagcca gttaatatgt gtaaacagac agtttgatag
    22081 ttgaattcgc cggttatacc ttttcttcct cccaataaat ctagtgatgt ttttgtccaa
    22141 tcttcacttg aacagacttt tgtccatgga tcgcctttac atttgtaggg tgctttcatt
    22201 gttagcaagt gcttgattgt aatagcgtaa atagttttct ccccgcgttt cactttatac
    22261 tctggaaaat aatctaatac tttatcatcg atacttttga ttaatccttg ctctaaagca
    22321 atgccaatca gcaaagatac aatacttttc gttgctgaca tgatatgaca agtatcgtct
    22381 tttttataac cattccattc atctgtataa acttctaccc catccttata tgcgacaatt
    22441 tgacatatat ttggttgtcg aaaaccaata aaatcatgca actcttgttt attcataaga
    22501 tattacctca ctttcttcta taagcataat gtcattaaaa atcgatttca attttttcga
    22561 ttcttcacgt aatacaggta ttcttatgga ctagacagcg ctttgggaag atggattctc
    22621 tgaaaaatat aaaggttcac tttatgagtg gataaaaaaa gcagcaaata cttcgacttc
    22681 tttaatttac caacattagt gaaaatcgat tcatctggag atttgtaatt tagagtcctt
    22741 gtcttgatta gaggtgtata aagcttttta ttagacattt ttaaattcca ttacaatttg
    22801 cttataaact aggtttttaa aggtgactat ggtaagataa tagagatatt attttgtgat
    22861 taggagtgta tatatgaata aaaatggaga atggagtgct gcacgacgga tattcattat
    22921 attaatggat gttattgtat acaatgcagc aatatatagt agtttcttac tgaagtttcg
    22981 tggagagatc ccattacgaa atttagaaac tttccaacac tcagcaatta ttatttcagt
    23041 gatttttatt gcgttgaaca ttttgttggg tgcatatgtt ttttataatc gaatgatcag
    23101 tgacatcgtg tttgtcacag tcatcggtca ggtattgatg acactaggga tcatggtagt
    23161 gacttttgcg ggccgctggt ttgcttttcc acgtcttgtt atcttacttt catttgttct
    23221 cggtacgctt ttcttaagta tctatcgtat tctcgtatat aaactttatt tacgcgtaag
    23281 tcgagataaa aaggtcgtca ttattgggtt agaaaaggat gtcgcaccag caatccaaaa
    23341 ttttggttca aagaaaaaca acaaacataa agtcgaagca gtcattcttg ataactatta
    23401 tgcaaacatc aaaaatatga ttaaagacat cgatattgtc tatcttgctt ctcatatcga
    23461 agaaactgaa aaaatcaaaa tctatcaatt agttactaaa aatgaaaaaa aattgttttt
    23521 gaatacaaca tttgaaaact tgacattgat caatccaaat attatgaatt tcgaagatga
    23581 aagtattatt gaagcatctg gatttagaat ccaacctgaa tatgaactat tcaaacgttt
    23641 gtttgatatc atcgtttcac ttgttttatt agttattgct tcaccattta tgttattcac
    23701 agcaatttta gtcaaagtga catcaccggg accaatcatc tataaacaag tgcggatcac
    23761 aaaaaatcaa aaggaatttt caatctataa attccgctcg atgaccgcca cagccgaagc
    23821 aaaatctgga ccagttttag ctaagagcaa tgatgcacga gtaacgcctg taggtaaatt
    23881 tattcgagct gtccgctttg atgaattacc acaaatcttc aatgtgctga aaggcgatat
    23941 gtcgatcgta ggaccacgtc ctgaacgtcc tttcttcgtc gatcagttca atgcagaaaa
    24001 cccttattac tacttacggc ataatgttcg tgctggtatc actgggtatg cacaagtcta
    24061 tggaaaatat gtctctgatt acaacagtaa attacgtttt gatttacttt atatcaaaaa
    24121 atattcattg atgcttgatt taaagatctt gctgcaaacc atcaagatcc tatttgataa
    24181 aatgtcctct caaggacttg aagaagacga aaatgtgatc tcattggcag aaattgcttt
    24241 tccgaatgaa aaaatctttc gctagttggg aggcgtaaaa atgaacaatc cgaaattcag
    24301 cataatcgta ccagtataca atgcagaagc aactattggt cgaacgattg atattctaaa
    24361 agaattggat tatgaagagt acgaagtcgt tttagtaaat gatggatcaa cagatcaaac
    24421 acaggaaatc attcaagaac tgattgaaaa tgatgaacgt tttgaattga ttactacgac
    24481 caatcaaggg cccggattag caagaaacga aggaataaga cagtcaaaag gagaatatct
    24541 cttattcttc gatgcagatg acacgccagt aaaaacgatc ttgtcagatt atgatcattt
    24601 gctagaaaag agtccaaaag cggatcttgt tgttagttcg tttgtttttc gtacaatgga
    24661 cgagggaaga atcgtttccg aaaaagaaaa cttagttaca gaatgtcact atctaactca
    24721 cgaagagttt ataaaagaca tgtatcagtt aatgaatgaa cagttgatgt atgttgtatg
    24781 gaacaaatgc tatcgtagcg atattctgaa aaataaccaa attctattta aaacttataa
    24841 tagttgtgag gatcgaatat ttaacttaca ttattatgaa tactgtcatc aagtgatcat
    24901 gaacccaaaa gtagaatata tttatgaatt tgaaggtggg aaggggatca ctaatcaata
    24961 ccgacctaac aagttcgaaa catttaaaga attctattca ttagcaaata ctgtaacaga
    25021 cgatattaat aaagacggta tggcggcgct tcttttaaaa gggacaactt cagttatttt
    25081 ttctatttat agtacctctg caagaacttc aaaagagaag aaagacgaag caaagcagat
    25141 attgagtgat ccagtgatcc gagaagccaa gcaaattgct aagacggatt cttcagcaaa
    25201 aaaaataaca aagttgcttt acaatatgcc agctccacta tttttatctg ctgtaaaagt
    25261 tggaagcttc gttgaagtga aaatgccagg gttaatggct gctttgaagc gagtatatta
    25321 gttaatggag gaaaatataa tgaaaagaat tttgcatttt cagggacgaa tgggtttagg
    25381 tggagcagag tctttcatga tgaatttata tcgtaaaatt gatcgtacaa actatcaatt
    25441 tgattttttg atttatgaag attatgcaga tgttcaagac tatcattcag agattgaaag
    25501 attaggaggc cgtatttttg ttgtacctaa tcctaagaaa aatattttta aatatttaat
    25561 agaagtgaat aagttactaa aaaaagaatc tttttctata gttcacaatc aggtttattt
    25621 tggcggggga attaatttat ggttagccaa aaagaatgga atcagacaga gaattgctca
    25681 tagccatgca actgaagatg gaaaatctca aaatattgta atgaatgtat tgcgtaaatt
    25741 tttaaccaaa ttgttgttac aaaatgcaac agactacctt gccgttagtc aagaagctgg
    25801 tgaaagtctg tttcaaaacc acccctttga gatagttcat aatggtattg atttagagct
    25861 ttatagtaaa aattcagaag ctaaggttaa taagagaaaa gaattggata tctcaatgag
    25921 tacttttgtt gtgggaaaca ttggacgatt agagaaacaa aaaaatcaat cttatttgtt
    25981 agagattttt ttagaaatac taaaaatgaa ttctgattct tacttgattt tagtaggtga
    26041 agggtcactt agaaataaac tgaaagccaa agcagtagaa ttggatatag agaaaagagt
    26101 aaaattttta ggagaaagaa acgatattcc cgagttatta tctgtgatgg atgtttttgt
    26161 aatgccttct ctttatgaag gtctgccaat ggttggatta gaagcacaag cagcaaaatt
    26221 aaaattagtc ttagcagata ctatttccaa agatacaaag ttaacaaata atgtggattt
    26281 tgtatcatta gatgaaacac cacaagaatg ggcaaaaaaa gtaataaaag agccgtatgc
    26341 taataaaata acacaagaac taaagagtta tgatgtttcg tacactactg aacaaatgga
    26401 gagtatatat agtagagatc attaaaaatg ttcaagatat tttaggagtg attatttttg
    26461 aaaatatgtt atttgatatt ggcatacaat gatattggca acttaaagag attggtcaat
    26521 cgattgaacg aaaatgcagt ttttattatt catatagata aaaaaactga tatagaacca
    26581 tttattgaag catttaaatc atatgataat gttgaatttt tatgtaataa aaaccgtgtt
    26641 aaaatttatt ggggtggttt ttccattgta caagcagaaa tcaatttagt aaagagagca
    26701 ttacaaaatg agaaatattt aaaatatgta ttattatctg gtgctgatta tccaatcaaa
    26761 gataatgagt atatttataa ttattttaaa aagaatagtt cagtggagtt tattcgtgga
    26821 atagatctag atcaaattaa acataaagaa ttttattata aacatataga tgtatatcaa
    26881 aaacatgatt atcctagaat taataggaat aacacaactg catttaaaat ttttagagct
    26941 ataattaatc gttgtctgag gatgattaaa cttcccccaa aaattagaca ccataaattt
    27001 gatttgtatc atggttctca atggtgggct ttgtcgaaag aatgcctaac agaattaata
    27061 caaatgtatg aacaaaatca acaagactac ctgaatttta aaataggtat gtttgcccca
    27121 gatgaaaaat tttttcatac actttttttt aattcctcgt tcaaaaataa aaatgttatt
    27181 ggaggaccag atttaccact tgaattgaaa aatattgaag aaactacttt acaaacttcg
    27241 aaattagcaa atattcatat tattgatcct tccatgaaca aatggtttga tgaaagggat
    27301 atagatcaaa taaaagaaag tgaaaaatta tttgtaagaa aagttaaatc ggattactct
    27361 gataaactat taaatagaat tgataaagaa attttgaaag ttggaaatat agatgaatag
    27421 aatagtacct gttttagaga agagtttatt aagtcgagat gcgtttcgag taataaattt
    27481 aatcatttgt ctgctttatt ttatgcctag tacttttaat gtaactaata tcccgatgaa
    27541 aatagctttt gcttggggtg gaattatagt tttgtatgag gtttttataa agaaaaattt
    27601 ttttaaaatg cgtttttctt ggctactgat tggagcaatg attagtttta tcttaactat
    27661 aatcattaac ag
//
LOCUS       DADLIO010000033        26603 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.033, whole genome shotgun sequence.
ACCESSION   DADLIO010000033 DADLIO010000000
VERSION     DADLIO010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26603
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.033"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(99..1229)
                     /locus_tag="JOX41_001544"
     CDS             complement(99..1229)
                     /locus_tag="JOX41_001544"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HAY6449292.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     gene            complement(1878..3080)
                     /locus_tag="JOX41_001545"
     CDS             complement(1878..3080)
                     /locus_tag="JOX41_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAY6449293.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="JOX41_001546"
     CDS             complement(3140..3343)
                     /locus_tag="JOX41_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAY6449294.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4717)
                     /locus_tag="JOX41_001547"
                     /pseudo
     CDS             complement(3485..4717)
                     /locus_tag="JOX41_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            4880..5692
                     /locus_tag="JOX41_001548"
     CDS             4880..5692
                     /locus_tag="JOX41_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAY6449295.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6716..6868)
                     /locus_tag="JOX41_001549"
     CDS             complement(6716..6868)
                     /locus_tag="JOX41_001549"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449296.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
     gene            complement(7059..7937)
                     /locus_tag="JOX41_001550"
     CDS             complement(7059..7937)
                     /locus_tag="JOX41_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAY6449297.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(7976..9094)
                     /locus_tag="JOX41_001551"
     CDS             complement(7976..9094)
                     /locus_tag="JOX41_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HAY6449298.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9091..11190)
                     /locus_tag="JOX41_001552"
     CDS             complement(9091..11190)
                     /locus_tag="JOX41_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HAY6449299.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(11241..12062)
                     /locus_tag="JOX41_001553"
     CDS             complement(11241..12062)
                     /locus_tag="JOX41_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAY6449300.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(12059..12868)
                     /locus_tag="JOX41_001554"
     CDS             complement(12059..12868)
                     /locus_tag="JOX41_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAY6449301.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(12889..13383)
                     /locus_tag="JOX41_001555"
     CDS             complement(12889..13383)
                     /locus_tag="JOX41_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAY6449302.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(13395..13883)
                     /locus_tag="JOX41_001556"
     CDS             complement(13395..13883)
                     /locus_tag="JOX41_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAY6449303.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            complement(13960..16656)
                     /locus_tag="JOX41_001557"
     CDS             complement(13960..16656)
                     /locus_tag="JOX41_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAY6449304.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(17084..18157)
                     /locus_tag="JOX41_001558"
     CDS             complement(17084..18157)
                     /locus_tag="JOX41_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAY6449305.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(18154..18981)
                     /locus_tag="JOX41_001559"
     CDS             complement(18154..18981)
                     /locus_tag="JOX41_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAY6449306.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(18982..19788)
                     /locus_tag="JOX41_001560"
     CDS             complement(18982..19788)
                     /locus_tag="JOX41_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAY6449307.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(19800..20885)
                     /locus_tag="JOX41_001561"
     CDS             complement(19800..20885)
                     /locus_tag="JOX41_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6449308.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(20902..21444)
                     /locus_tag="JOX41_001562"
     CDS             complement(20902..21444)
                     /locus_tag="JOX41_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAY6449309.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            21702..22691
                     /locus_tag="JOX41_001563"
     CDS             21702..22691
                     /locus_tag="JOX41_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HAY6449310.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIITFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            22688..23425
                     /locus_tag="JOX41_001564"
     CDS             22688..23425
                     /locus_tag="JOX41_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HAY6449311.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            23422..23973
                     /gene="coaC"
                     /locus_tag="JOX41_001565"
     CDS             23422..23973
                     /gene="coaC"
                     /locus_tag="JOX41_001565"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HAY6449312.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            23989..24621
                     /locus_tag="JOX41_001566"
     CDS             23989..24621
                     /locus_tag="JOX41_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAY6449313.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            24706..25353
                     /locus_tag="JOX41_001567"
     CDS             24706..25353
                     /locus_tag="JOX41_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAY6449314.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            25358..26341
                     /locus_tag="JOX41_001568"
     CDS             25358..26341
                     /locus_tag="JOX41_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HAY6449315.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
BASE COUNT         8143 a         5616 c         4511 g         8333 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac agtgatgatt
     6361 cctaataaag aaaagactac aataatattt ttctaactta tcgccttcaa agaaatagtt
     6421 tcttattttt cactaaaata aaaaatttat tgcaaaaaaa atagaagtga caaaattatc
     6481 aatcatttca aggtaatata actacctgag tttattatcg attaaaatgc taactacatt
     6541 tgcaagagaa gcgagagtta aaggtaaata tagaatttct acttttttag caatagaaat
     6601 aggaataaaa tatttaaaat gtatagaaac tttctttttt tttcttgcta tctttttata
     6661 atcacaactc tctataatag aattacgatt tattttatac ggctgaaaaa atctatcacc
     6721 aaaaaaattc aaacattaag ccaaggatta tgaagtcaac atttcgaaaa atgaacatac
     6781 attggtaagc aactataact attaccacag acataaagta acacaatata ttactattta
     6841 agtgtacgcc accagtgaat atcctcaagg tatacagcgc acaacaaaaa gaaaaaagga
     6901 aacgcagaag catttccttt cagtgattta atgaaaacaa cacgatttga cttagagcct
     6961 ttttatttga attcattttc gctttatcca acttcatttg atcatttgat tactcggtta
     7021 aatacttttg acatgagtat caatgaaaca ttcattaatt atggttgctt atttcttacc
     7081 gcttttctgg ccaatgctaa tccgccgatt attccggcat tatcacctaa ttcgggcgta
     7141 ataatgtagc tatcaattgg tggtatttca acatatccat ttataagctc aacaaattta
     7201 tcctgaactt ttttcttcat gtgttcttgt ttcattacac caccgccaaa aataattcta
     7261 tctggcgaaa acatcagtgt tgtattgtat gcacattggg caaggtaaaa ggcttcaatc
     7321 tgccaaaacg aatcgtcagc caataaattc tggcctttta cacccaaccg tttttcaatc
     7381 gctggtcctg ctgccatccc ctctaaacaa tcttggtgga agggacagtt tcctgaaaaa
     7441 ttgtcctttg gatgtcgctt gatcaacata tgccccattt ccggatgact gaacccttcc
     7501 acgaaagtcc cattgaacaa ggcaccacct ccgatacctg ttcccacagt gaagtatgca
     7561 acacctgcta accctttgcc agaaccagca acatattcac catagcaagc cgcattgaca
     7621 tctgttgtcc attcaatcgg aatattgaaa tattgcttta gcgttcctac aaaattgaaa
     7681 ttttgccaag caagttttgg tgttgatgtg atatgaccga aactcgttga tttgcattga
     7741 atatcaattg gaccaaagca gccgaccccg atgcctgcca attgttcctt aaaaggttta
     7801 aaaaaatcaa tgacctgctt cattgtttca actggagttg ttgtgggaaa actgactctt
     7861 tccaaaatcg ttaattcctc agtaccgact gcacagacaa atttagtccc tccagcttca
     7921 attgccccat atatcatcat aggttcctcc cttcgaatat gtgaaaaaca cttcattaac
     7981 gcggcaagcg ttctcgatca gtgaaatgac gtttagtatt tcctgaagct tctgttgaat
     8041 accagtaagc gacactagca acatcgtctt gccgctcaaa taagcgaaca tcatcgttgc
     8101 cgatttgttg taaagtgacc gataaatctt cggtaaaaca gatggggtct tgaagatgcc
     8161 aacgataaag accatgtcgt ggcattgcgt cgtcaccaaa ggcatgaacg gcattcaatt
     8221 ttcccgtttc aaaacgatct cttgtggcat ctctatttga ttggtaagga taccctaaaa
     8281 aggctgttga atagtttttc gcatgtggac gtccgaactc atcgtactca tgaaaggccc
     8341 acgccccgcc aaaataatct tctgaacctg ttgaggttac ggtcggatac tcactatccc
     8401 catcaatgta gaatttaaac tcgccttcgc cccaccaata acgttctagg caggtaagcg
     8461 caaggtaagt acccacgtaa tagccttgac cctttaatcg atcaattaac ttataatcct
     8521 cctgtaattt ggtaatgcgt tcccgatgcc aatttgcgtg aaaatatagg ctattttctt
     8581 ccaattcgtc caccaaagcg taatttatcg tataaaaaaa tgaggacata tccttcggat
     8641 gtaaattctc gatcgtaatt ttagcggatg tttggaaagg catttcgaaa taggaattaa
     8701 agccccctgt aggattaacc actatcggca acgagttcac ctcgcaacgc tctccaaacc
     8761 cattacaaaa gaaatcccct aaaggacttt caacagcagg gctatccgac ccatcccaat
     8821 aaattcttaa gattaaatca cgtaaaacaa aactgccaaa ttctgttcga tcacgaatcg
     8881 tcatccacat atgacgaatt attcccgttc cagtaatatc cgcaatcaca gtttcttcac
     8941 cagaagtcag cggaattgcg ccacgacctt tgcggcttgg tcctagctcg cttggcaaca
     9001 tcgcagcttt acctttctcg cctgttggat tttcgggagt gattgctcga ctctggattt
     9061 ttttaaattg ggtaatattt tttagtatac tcatcttttt ctcctttgaa tgtgaatcgt
     9121 ttttcccttt tctacgtgaa gaattttttt cgtatcactt attttcaatg gcttttctga
     9181 caaatttgaa atactcaact cggattgcgt acattcaatc gaaatgaagg cttgaccgaa
     9241 cttcaaattc ttccaagaaa acgttaaatt atcaacagga tcaatttgca atactccttt
     9301 tttgaatttc aatccgaaat attgactgat cattaggctg acaaaaagac ccgatgccca
     9361 gccgcatttg ccgcagccaa agtctcgcac gacttctcct tgttgagcct ctaagcgata
     9421 cggccaccac caccacgaac cgtctaaatc tgccaaacaa attagttctt ctaatcgggt
     9481 tacgaaagct tgagggttgt gcagctcgct cattaaaaca gtgataaagc caggaaaagt
     9541 ggcgccggat tctaatcccc aagtgatgcc tttgatttcc tcgctatagg ttggattgaa
     9601 agaactagca gaaaaggcca tggtgttctg atataaatga tctttattat ctaaaaattg
     9661 ataaaaaggc atcaacgtag tgtctgattc ttctccatca tgcatcaata aattaatttt
     9721 tccatccaca atcacatcac ttaaaaagat taacccttgc tcaagaatcg gtttttgata
     9781 gtgcttcact gaataggttg ttttctcctc atcaccgatt ccctccaaaa attgctcacc
     9841 aaaaggacca tcgatagtca tttgtttaca aattgattcc tttagtttac aggcaatgtt
     9901 tttgtatcgc ttgctaagac tcagttgttc tagggcttca aaaatttctg caagtccaat
     9961 acaggccttc caaagacaaa gattgctgcc ggtatgatac tttccaagtg caaaggcgtc
    10021 tgataaccaa acagatggaa aaagcattgg ttcccctgac cgacgttgag ctaatatgtc
    10081 ctcaataatt cttgaagcat tcagtagaac ctgcggacac cgctcaaaga attttgtatc
    10141 cccagtatgt tcaaaataaa gactagccag taacgcactg gataacgaat tactcagaga
    10201 atgattgata cctcctgtaa attttgaacc aggaaactta acgccatatt gatcaaacca
    10261 tagaaccgtt ttttgacata actccggttc aaacatggtg aatggcaatg atgcgtaata
    10321 catatcctta ttccaaattc gattagtagc aggatagctg ccccaattgc tgccgacgac
    10381 ctgtccctgt cgattcatac cgaaactaga aaagctttga taaagtgcac gacgatagag
    10441 atggacaact ctatcgtttg gcattgacag ctgcccaaat agctgagcaa aatagttcaa
    10501 tgtttccttc agccattttt cgatatcaga ttcctgaaaa gtcattactt cttcaaaagc
    10561 atttgggtcc acaaaagcaa tggcgaagct tgccacttcc tgttgtgcga tcgtgtcctt
    10621 atttcctttt tgagaaatca acacattttg ctgatccgaa tacttctctt gatacgaagg
    10681 cacatctttc actgaaactt gaaggctttc gtgtgtttca ttcacaatgt aaacctgttg
    10741 aacaagcata cttaaacgct tattagccag tatgggagca aaggatacta caatgacctt
    10801 aaacgtcgaa taatgatgaa tatatctagg caaacagtct tgaatcacat cgacttcaat
    10861 acgatgatcc gattctgaca aatggtagac aatcccgttt acttcaacct ttaaggataa
    10921 cgaattggtt tgagagagct gtttattgac ccaaacacct ggtttttcct cagttagtaa
    10981 attttctcga taaaaggtca acgtttgaat cgtcccgcaa acatcaaggt ttgctaatgt
    11041 cttttgatta cttacatcga aggtcaatcc ctttacatca ggaatattcc gatagtagct
    11101 gtattcgttt gaagtagtca catttccgtc gtttaactca gcattaaaaa atgggtgttt
    11161 gggtgaataa attacttcat taatagtcat cttttccctc cttgctaaaa aaactgcagc
    11221 ctagtagctg cagcttccta ctatgcgatt ccaagtaatg acaataaaat tcccaagacg
    11281 accattccaa aaataatttt gatgacgccg acttttttat ctagtaattt gaaacagctc
    11341 aatgttacca ataacggtac aattccttta aaaatactat cgaggatttc ttggacattc
    11401 attagttctt cgcccttcat tgaaaagctc aaaacggtat tgaatttgac catactgatc
    11461 gtcattgcac ctaccatgat cagacccaag atactagcag cttttgtcag aatttcaatt
    11521 aacccgttcg catacagctt ttcaatatat ttagagccta atgaatagcc taaaacgccg
    11581 ccatagtatc gcatcaagta attaggtata ttgaacataa ctaaaaagat aattggtgcc
    11641 aaaatatttc cggcattggc taagttgatc gctagtcccg cggtaacgac acgccaaact
    11701 ccccagaaca atgaatcgcc aattccagcc aatggtccca tcaaactcgt tttgatcgcg
    11761 ttgatacttt ccacgtcaaa accagctttt tcagaatttt ccttctccat cgatgccgca
    11821 atccccatga caaaggacgc gcaaggaatg gtcgtcgaaa aatactgtgt atgacgttcc
    11881 agcgccgcag ctcgatcttc ttcacttttg tagaaatgat taatgaaggg catcatagaa
    11941 taggcgaaac caccgccgcc catcgtcacc ggattcaccg aagcatacat agtcatcgag
    12001 cgccaaaaca tcttccgaac caattttttc tcatctttag aaattccatc agctaatttc
    12061 attgaaagaa atcctcctct tcttggtcaa gcgttgcatt tacagcagca tcgctttgaa
    12121 ctgcatgaac agatatattt tttagttgta gatctctttg ggctataaca attgcaataa
    12181 tcgttccaac tgcggcaatt gcaatcaatg gtaactcgag atacgccata acaacggccc
    12241 caaagaaaaa ccacacagca atatttttac tccaaagcat ccgtaacagc atcgccatcc
    12301 caactgccgg cagcagattt ccagcgactg ttaatccgtt catgatgacc tctggaatat
    12361 tatccaagac gcttttgaca acatctgctc caaataaaac ggcaaagaat ggaataagag
    12421 cataaagcgc atagtggaca aaccacataa agaagtgcag attgatgatt cctttttgat
    12481 caccagattt tgcaaatttg aaaaatttag cagccatcgg tccacataca aaagaaaaaa
    12541 tcatattcat taactgtaat cctaatactg ctagtggaaa gacaatggga ataatcgcat
    12601 ccacgtttcc tcccattttg attgcgaacg ctgtagccag cccagcagcc aaagaaggct
    12661 ccgccgtact agagattccg atattgacga cacccataaa gatggcttct agtgacgccc
    12721 cgacaatcaa ccccgtctgc aaatccccca tcaacgctcc tgctaacgga gcaacaacaa
    12781 tcggacgact cagcatggac atcccgaaca tttcatgtcc agcaactcca ataaaaacgg
    12841 ccaaagcgac tacaaatgca tcatacataa tttttctcct tcctttttct aaaaatcact
    12901 caaaatagag atagctgaac gtttttccat cgccggtgta ggctgaaaaa cggtatctgg
    12961 ataaagttca actaattctt ttaagtcttg aatttctgac gtcgttaaca tcacttcctt
    13021 tgataaggtt ttcttatctt ccgatggcgg tgtcattttc ccagcattcc ccacgttcat
    13081 taattcgatt tccgttggga aagctttcgc aacttttacc gcatctttga cattagggac
    13141 taaaaccatc aagcgcatgt ccttcgcccg cggatctttt aacaaatgaa tcgcgtcatc
    13201 aactgtttta ataatgactt tgacattcga tggtgcagcc atcttcaatg tcatcttttg
    13261 aatatcgttg gtagccgcct catcgcttgc tactactaac ccggttaaat ttagactctt
    13321 tgtccaagtc atcgctactt gtccatgaat taatcgttca tcaattcgca ctgctttaat
    13381 catttttctt cctcctaaaa aaaatcttcc tcttcattta ctacatgtac ctcatcaaga
    13441 atggtcatct ttaattcctg ttggcattta tttaccagtt cctgaatatc ctcctttgtt
    13501 aattccttgg ttgccaatac tatttcgagc agaattggca gattaaagcc agacaaaata
    13561 gttacagcaa tctctttctc caaaaaggtt ttggtaatct tctgattgac acttccgcca
    13621 aataaatcgg taaaaacaaa aatctgatcc tgctcgttca cctggtttac aaatacattc
    13681 aactcctgtt caaaatcaca ctcatccaca taagcattaa tcaccgtaat ctcttgaacc
    13741 ttccccgtca gtaattgaat actgctaaga aagcctgaag ctaagtgacc gtgagtcgct
    13801 attagaattt tcttcatatg gttaattcct ttctttctgt tcacttttat ataagcaatt
    13861 cctgtgccaa cttttaaaaa cattggttta atcacgttaa ttcacattaa aaaaagtgtc
    13921 taacctaaaa aaaacagatt agacactttt ttagacactt tatttttgaa tatacggtcc
    13981 taataattca tagagcagcg aaagctcata agcattgact ttaaaattat atttcatctc
    14041 cattgattga aaaatacttc tagaaacata ataaaattca tcttcatctg gtttcaaatc
    14101 ataattcggt tcttcagatt tttctgtccg agccaagaat aaacgttcca tcatcaatgc
    14161 cgtatgcata tagagattta gttttacacg gccatttaaa gtgaaatgat agtaattttc
    14221 atatttagaa atgactgttt ccacttcact catcacgatc gttgggttca gaaagttcaa
    14281 acggtccgca attccttcca acgaaaagaa ttttactagc tcctgaatca agcggttaaa
    14341 ttctgccggc ttcatttcag gactcaaaat atgctccaaa ttggctgctc catcaccgtc
    14401 taagatgtca taaacattaa tattaggaat tgaaaaggaa cgtggaagat ccgaagtcgt
    14461 gatgaccaat tttgtcttgt caaaataagt ttcatcattt tggtcgatta attcacgtag
    14521 ttctctgtag tccttcgtga aaacttcgat ggattcatcc gataaatgat gacgaaaaac
    14581 atctttcaat ttgtccgaaa tccccaaacc cgacatacag gaaatgataa tgttgctact
    14641 ttgagaaaag ccttcaaagt attgaacatt gattgaatac ttgtctgctg catcctccgc
    14701 aatctgttta aatggcgcat tcatcgtcat cttcaagcca atatcaagtg caatggaagt
    14761 cgtcaaatta ttcagaagaa gtaactcccc ttttaaatcg ttcttgatct gtgtgtaaat
    14821 ttgatttaaa gagcccatat ctacgatcag cactagacta tctgtattca cttgccgttt
    14881 cacgaaattc cttgtcgatt cgacaatctc tgacacatta ctctctactg gcatatccaa
    14941 cgcttcaaaa acataattgc cgcataattg attcactact gcttgaatgc tgctagccgt
    15001 actatctccg tgagcaagca acaggccctt cagctcgatg gattcatcta cataatcaga
    15061 taaagtcacg acaataagca gtcttagaaa gttctcgtcc ttttctgaga gcggtggtaa
    15121 atgctccaag aactgattac ataagtaagt cgtccgaggt agatttgcag ctaatgtacg
    15181 atttatcccg gttaagtctg tcttatagct tggggaaatg acataggatc tgctaataat
    15241 ttctgcaaca ggtccactcg tcgtcaatcc gtacgttttt cctaaaacgg atacccagac
    15301 ctttctaaac atctgaatca tcaattttct actcattgat aaaaaagaat ccttatcaat
    15361 gtgatgcacc aaatgctgta cttcattctt tatcgaagaa aaattttcat tgaaattacc
    15421 ttcatttatc agctgagtaa ttttttccaa aatcgaatca taatcaaacg gtttgattcg
    15481 atccgttttt atcttttgat ttttctttat caataaacta gcaatcggca agctttctac
    15541 ttcggattcc agcatattta actgaatcaa gatctcattt ttcccaatcg ttaatggttc
    15601 ttcttgtgtt cgactataca catccgcaca actgatttta atgatattct tcagcttacc
    15661 aatattccca ctaaagggat gagataacat taaagacaag gcttctcttg aaacaataat
    15721 atctttttgt aaaacatccg cttcattttg aaaaaataat tgaatcagct ctaatcgttc
    15781 tcgaatgggg cgatcttcaa aagttggcaa cataacacta atttgaatac gccgatcaaa
    15841 ggtgtctaat aaataatttt cacctttttc cgtcgtggcg aaaataaaac gaaccttagc
    15901 agaatgccaa tttacatttt caccgactgg acgatagttt ccagtatcaa taaatagaaa
    15961 gagcttttct tgattttctt tcgataggcg atggacctca tcgagaaaaa gatagccgtt
    16021 gttggccgtt gccaataaac catcggtatc cttttcagcc cccgtaaagg cccccttctt
    16081 gtatccaaac agtgttgccg aaagcagttc gggattgtcc gcataatcgg cacagtttaa
    16141 gatagcaaat ggtgcatctt tttcaataat ttgctcatgg atagcgtatt caaaaatttt
    16201 tgtggctaaa aaactttttc caacacccgt ggctccattt attaatacac tgagtccgtt
    16261 aggcggatat ttgacagcgg ctatacattt ttgaatgacc tctctcagac ttccgtcatg
    16321 accaactaca gaatgaaagg cttcgtttat ttgctccgta ttatctacaa ccgcatattc
    16381 atctaaaggc ttccacaaaa caggctttcc cggtaatttc tcgacctttt tatcttccac
    16441 taatctcgtc aaataatggc tggcattctg acgagagata cctagattct tcgaaatttt
    16501 ctcggcagtg acagaagaca tattccctgt tagtcgtatc agctcatcaa aaactcgatc
    16561 tttagcgctc tttttcattt tttcctccag tttaatgtgt ctaaaagcat aataaactat
    16621 cggctgcaat atgtctattc tatatttgta ttccaatttt tactttgaaa cacaaatagt
    16681 cgaatatttg cctcagatat ctgacaaaat aatttatcta ccaatttagt ttttatctaa
    16741 tatgattttt atgttttttc atagctacaa atattgaact ggattcatat attagtttta
    16801 ttaatagatt acagaagggt taagtatatt tgcatagttt ccaattactt tatccttctg
    16861 taactttttc aatcttagat ttactagccc gtctcgggcc ctattttaca atggttttgt
    16921 ccacttttct ctggtagaaa aacgtggtag aaaaaataaa ataacacaaa aaaagcggcg
    16981 tttcatccgc ttttggtaga agattggaaa actcagatag aaaaaggacg atttttagct
    17041 ctttagaacg ttgataagtc cccattctta ctgagttttg ccattatctc ctatacatct
    17101 tgaattctaa gaataggtca ttatagatgc ctaggtattt cgatcctaga tctttgtaga
    17161 cttcaagatg ggagatcgtg tcatcagatg gatagaattg ttcgtccgac gaaatgtctt
    17221 ttggcaataa cgcttttgct tcttcatttg gtgtagaata accaatatac tctgcatttt
    17281 gtgccgcatt ttccggttct agcataaagt tgatgaaatc ataggcacct tctttatttt
    17341 tcacggtttt tggcataacg atattatcaa accaaagatt ggatccttct ggtgggatca
    17401 cataatgtaa atgttcattt tcccacatca tatcggcagc ttcgccagaa aatgtcactg
    17461 ccacggaggc ttcttcattg atcatataca ttttgatctc atctgccacg attgctttga
    17521 catttggtgt taaatgattc aatttatttg ctgcttctgt cagctgtgcc atattcttac
    17581 tattcaaaga atagcctaaa ctattcaaag aaagccccat aacttctcgt gcaccgtcaa
    17641 tcagcatcaa actgtctttt aattccggct tccacaaatc atcccaatgc ttaatttgat
    17701 ttgcatcaaa gaatttatcg ttatatacga tccctaaagt tccccaaaaa tatggaatcg
    17761 aatactgatt atctggatca aaatccaagt ctaaaaatcg tggatcaata ttatttaatc
    17821 ctttgatctt cgaatgatct aatggaagta ctagtttttc tttgatcatt ttttggatca
    17881 tatattcact tggtatagcg atgtcgtagt ttgtcccacc ttgctggatt tttgtgaaca
    17941 tcgcttcatt agaatcaaat gtttcataat tcactttgta tccatattct ttttcaaatt
    18001 tcgtgatcaa actaggatcg atataatctc cccagttata gatggtaagt acctttgctc
    18061 cactcatgcc acttgttttt tcaagttgac gaacaccaag cagcagcacc gcaataatga
    18121 tgagaatacc taaaaacaga gattgtaatt ttttcatcgc agccgtgcca ccccctcgcg
    18181 tactcttctg tttttcttca gccgttttgg acggttttct ttactaataa agtagtatcc
    18241 aatgaccaat atcatggaga acaagaaaac taacgcactt agcgcattga tttctaaact
    18301 gattccttgt cttgcacgag aatagatctc tactgagagc gtcgtaaagc catttcctgt
    18361 gacgaaaaat gtaaccgcaa aatcatcaag agaataggta aatgccataa aatatccagc
    18421 tatgattcct ggagaaagat aaggcaaaat gatatttttg actacttgga aattattagc
    18481 accaaggtct ctagccgcat cgaccattga atcgttcatt tcctgcaatt ttggcaagac
    18541 catcaagacg acgattggaa tgctgaaagc aatatgggaa agcaatacac tctgaaaacc
    18601 taatccgaat cctagtagtg taaagaaaat caagaaacta gcaccgataa taacatcagg
    18661 agagactaat aagatgttat tcatgctcaa caacgctgtc cgtgcacgtc gttttttcgt
    18721 gtaatagatt cccatagccc caaatgtccc gatgatcgtg gcgatcaatg cagataagaa
    18781 agccagcatg aacgtattca atacgataat gatcaaacgt gtatcttcaa aaacagcttc
    18841 ataattttcc caagtaaatc ctgtaaagct gttcatcgtt cctccttcat tgaaggaata
    18901 aaaaatcaga tagaagatcg gtgcatataa gaataaaaag acgatcccta aataaagata
    18961 cgaccattta aattttttca tttatgagcg acctcctttt ttcttctcgc ctgtcaggag
    19021 catcacgatg aacatagcaa tgattaaaat cacaccgatt gtagaaccca tcccccagtt
    19081 ttgtgtaacc aagaaatgct gttcgatagc cgttcctaaa gtgatcaccc gatttccgcc
    19141 aatcagacga gtcagcatga ataaagaaag agaaggaata aatactgctt ggacaccact
    19201 tttcacacca tttaatgata acggaaaaat cactcgtcgg aaggtctcaa agctattcgc
    19261 gcctaaatct ctactagcac tgatcaaaga aggattcatc tcttccaatg cattgaaaat
    19321 tggcataatc ataaatggaa tctcgatata cgttgccacg aacagaaaac tgaagtctgt
    19381 gaataatatc tgtttcggcc cgatcccgat aaaatcaaag aaatgattca cgctgccgtg
    19441 cacactgaaa atcccaataa atgcgtaagc tttaagcagc agattcaccc atgtaggcaa
    19501 aataatcagc atcagccata attgcttgtg cttcagtttt gttaaaaaat aagcagtcgg
    19561 gtaactgatg atcagcgtga aaaacgtgat caaaaatgca taccatacag aattgatcgt
    19621 catagaaagc gatgtccccg acgtaaaata agatagataa ttattcagcg tgaattgccc
    19681 attcatatca aaaaaagatt gataaatgat cattaataca ggcgcgatca cgaataaacc
    19741 gagccacaaa atataaggga cggaatagat cctgcgcatt gttttcattc ttgtcccccc
    19801 tattcttcgt agctgtcaag acgtgcatcg aattcttctt cagactcgtt gaaacgcatg
    19861 acatggatat cttctggctc aaaggccaat cctactttgc ttccttcttt agcttttttc
    19921 gttgaatgga ccatccattc attttgctgt tcatcataac agatgatttc ataatggaca
    19981 ccacgaaaca gctgagtatc gaccgttacg actagttttc ctttatctgg tgtcgtgatc
    20041 gtcaaatcct ctgggcgtaa aacaacttca actggttcat ttagacgcat cccgccatcg
    20101 acacattcaa attgcttacc aacaaactca actagattat cttcgatcat tacaccgtcc
    20161 acgatattgc tctccccaac aaaatcagca acgaaatgat tgattggctc atcataaata
    20221 tctacgggtg taccactttg gacgattttc cctttattca tgacaaaaat ctcatcactc
    20281 attgccaacg cttcttcttg gtcatgagta acaaaaataa acgtgattcc taatcgttgt
    20341 tgcagatccc gcagttcata ctgcatatct gtacgtagtt tcaaatcaag cgccgataac
    20401 ggttcatcta atagcaatac tttcggttca tttacaattg ctcgtgcaat cgctacacgc
    20461 tgtctttgac caccagacat ttcactaatc tcccgttttt cgtatccagg aagctggacc
    20521 atacgcaaag catcttttac cttcttttcg atatctgatt tggacatttt cttgatcttc
    20581 aatccaaaag caacgttatc aaaaacattc atatgaggaa aaagtgcata atcttggaag
    20641 actgtattta cttgtcgctt attagctggc aaatcattca accgtttccc ttcaaaatag
    20701 atgtcccctt ctgtagcttc ggtgaatcca gctataatac gtaggatcgt tgttttacca
    20761 cagccggaag gaccaagcag tgtataaaat tttccttgtt cgatctcaaa acttactttt
    20821 tttaatactg tttcatcatc atagcgtttc actacttgat caaatgaaat gattggtttc
    20881 cccacgtttt taccccctat attacaaata tgattgcgtt gcaacaatca atacttttgt
    20941 tcgttttttg agatgattcc ttaattgatg ttgttttgtc gcttgataat agatcgactg
    21001 tcctgctttt gccacataga ccgtctctcc taagcttaac tctaattccc cttctaatac
    21061 aaaaataaac gtttcagata atgaaggttc aaacgtctta tattctcctg caccttcaaa
    21121 agtcagcaag acaggctcca tttctttttc attcgaatca gccacgagcc attccaattc
    21181 atacccgttt tcttcatcga aataaaccgt atgatcttct tttgaataaa ccacttgcag
    21241 attcgctgct tcttgatgaa aaaattcttc tggagtcaca cctaagactt caagaataga
    21301 aaagaatgtt tccattgatg gtgaacttaa atctcgttcc aactgggaaa tatacccttt
    21361 tgacaaatct gtgcgttcgc ctagttcttc ttgtgtcaaa ttcttttgga tgcgcaaatt
    21421 tcttaacttc tcaccaattt ccataatttc ctccgaatcg aagttttcta atagtaaact
    21481 tcctgtttac taccactcgt attagtatac gaaatttatt gaaaaaggca accctttgta
    21541 aaattttttt tgctgaatat ttctttatct tttggaataa attctagttg tttgattctt
    21601 tatttttcac ctaatttttg tctaaattta cggaagaaca agaataaaag agtaggcttt
    21661 atggtatgat aaaagaaaat tttaaaagga gtgtctcacg aatgaacgct tttcgatctt
    21721 ttcaggtaat aaaggaacct gttttccata cagcaatcag tgatctgcca tttactgagt
    21781 tggctgaaaa tgaagtcttg gtaaaaattg cctattctga tgtcaattat aaagatgcat
    21841 tggcaatgag cgagtctggt caggtgatac gaacatatcc gatgactcca gggattgatt
    21901 tatccggaac tgtcgtccaa agtaacaatc cacgtttttc aaaagaagat cttgtacttg
    21961 ctactggttt tgggcttggc gtcacccatc caggcggtta tagccaatat caaaaagtac
    22021 caggagactg gttagttcct ctaccaaaaa atatgacgct gcgtcaagcg atgatccttg
    22081 gtacagcagg gtttactgct atgttgtgtg tgaacgcttt aatccgtcaa ggtatgacct
    22141 ccgataaaaa agttgtcgtt actggtgctt ctggcggtgt aggcagtaca gcgatagccc
    22201 tgttacataa actaggattc cagtcaatca ttaccttttc cagaaaagaa gagtctgtca
    22261 catggctaaa aagtctaggt gctttgcaag tcgtacgacc tgatgaattt ctgccagaga
    22321 caacaaaagc tttaggaaaa cagcaaatcg actatgtcat cgacacagta ggtggcgagc
    22381 agctaagcag tcttcttcca ttgatctctt ataacggtgc agtagcttta tgtggcaatg
    22441 ctgggggaat caaactaaac gcgactgtct tgccttttat tctgcgaaac atccagttga
    22501 ttggaattga ttctgtcaat gtaccaatag atcaacgtct ttctttatgg caacagatgg
    22561 cggatttgca gattgcagat gaactggtcg tccaagagat tactctggat caattgcctg
    22621 aaacagcatc taaactactt gctggaacac accaaggaag aacactagta aatgtaggtg
    22681 accataaatg aagattctaa tcacagctgg aggaacgact gaaaaaatcg atcaagtacg
    22741 tgctattaca aatcattcga caggacgatt agggcaagca ttagctgatt atttagctgc
    22801 caatccggat accacaatcg attacgtgac tacgaaacaa gcactgaaac cgaaaagaca
    22861 ctccaatata acgatttata cgatcgaatc tgcactggac ttatttttac aattagaaga
    22921 actaacgaaa aaagaacact acgatgcgat tatccacagt atggcagtca gtgattttac
    22981 tcctgctttt agtttttcag aagaacagct ggcaaaaaac ctacccactt cttcaacgca
    23041 agaagaactg gacaattggt ttgcggaaaa tgaacagaca gataccactg tttcaaagat
    23101 ctcttctaac accgagcatc ttgtgctcgt tttgaagaaa acaccaaaaa tcatttctta
    23161 tctacgtgaa tggcagccaa aagcaaaaat cattggtttc aaactattag tagatgtacc
    23221 aaaggaatct cttctggcag tcgcaaaaaa tagtctgata aataacaaaa ctgattttat
    23281 tttcgcaaat gatttgacgg aaatccatgg cgagacacac cacggctatc tcttatctaa
    23341 agatggaaca gtggaagaag ctcaaagtaa atctgagatt gctgcattga ttactgagaa
    23401 aattagactg gaggaatcaa aatgaaaaag atcttactag gcgttactgg aagtatttct
    23461 gcttacaaaa gcgctgatct tacaagtcaa ttcgtcaaat taggtgccca ggtagatgtg
    23521 attatgtcta aaagcagcac acattttatc acgccattaa ccttgcaatc tctgtcgaag
    23581 cgcgcagtcc atacagacgt catgcaagaa tcaaatccgc aggtaatcaa tcatatcgaa
    23641 ctagcaaaac aagctgactt gtttctcatc gcgcctgcta cagcaaacat tatcggcaag
    23701 ctagcaaacg gcattgcaga cgatcttctt tcaacagtcg caatggcgct tccagtggga
    23761 acaccaaaat tgattgcccc tgccatgaac acgaatatgt atcaaaaccc gatcactcag
    23821 cgtaatctgg aaacattgag atctgtcggc tatcaggaaa ttgaaccaag agaatctctt
    23881 ttagcttgtg gagattttgg aaaaggtgcc ttagctgata ttcagacgat catcgaacag
    23941 gtcatgctga ctcttaatga aagaaatgct tagaaaaaag gagtacttat gaaaaataca
    24001 aaaaacttta cattaactgc gatgttttta gctattttga ttttattagc tgttacgcct
    24061 ttaggtttta tccctatcgg tccaatcaat gcaacaacca tgcatattcc tgtaatcatt
    24121 gcttcgatcg ttttaggacc aagactaggt gcttttcttg gcggtacatt tggactgatc
    24181 agcatgatcc gtagcacagt tatccaaaca cctttgtctt ttgtcttttc tccgtttatc
    24241 ccagtcatcg gaacagaaca tggaagctgg aaagccttgc tgatcgcgtt tattcctcgc
    24301 atcttgattg gggtggttcc ttatttcgtt tataaaggtc tgcgcaaact aatgaaacaa
    24361 aaagcagatt ccgtttcttt attcttagct ggactttccg gttcattgac caatacgatt
    24421 ttagtgatga atatgatcta ctttttattc cagcaagatt atgccaaagt catcggaaca
    24481 aatttaaatg ctgtttattc agctattcta gcggttattt ttacaagtgg tatacctgaa
    24541 ggaatcgtcg caggtcttgc gactgcagca gtatgcaatg tcttgttaag atacttcaag
    24601 cacccttctc ttactaactg atagtcatcg tagccgatct ctgatttttt tctcttttgg
    24661 tgttactatt gaatggaaag atttgacgtc gaaaggatga tccaaatgaa aatttttgtt
    24721 gtaggtgcaa acggacaaat tggccgacac ctgataaaag atttagctcc aagttcccat
    24781 gaaatttttg caggggtgag agatgttgct tcccaaacat tagtaaaaaa agagaatgtt
    24841 tcgtatgtct cttttgattt aacttggtcc gtggaaaaaa tgaccgaagc attcaaaggc
    24901 atcgatgtat tgatttttgc tgccggctct caaggaaaga atcttctgca agtagacttg
    24961 gatggcgcaa tcaaaacagt gatcgcagct gaaaatgcgc atgtctctcg ctatctgatg
    25021 gtcagtgctg tttatgcaga tgaaccagca aaatggcctg agtccatgac agattattat
    25081 attactaaac attatgcaga tgaatggctg aaacgaacta acttagattt tgtcattctt
    25141 caaccagtca cattgactaa cgatgaagaa gttacttcca ttcaattaac taagcctaat
    25201 gagaaggcat caaaaacgat cactcgctct acagttgctg ctgtacttgc cgctctagtg
    25261 gaagaaacgg atatttctcg tacgactcta gtactttctg aaggtagcaa agagttgaat
    25321 acagcattcc aagaatgggc aaaggaggaa tagatccatg cgtgccattt caatcaagca
    25381 tcctggttct gtagatgtat tagaacaaat tgaagtgcct gttcctaaac caaaacaagg
    25441 cgaattactg atcaaagtcc atacagcagc tgtcaatcga acagatatta tgaaaagaga
    25501 atcagtctct ttgaaacctc cctaccctat tttgggagtc gaagtagctg gagaggtagt
    25561 tgagaataaa agtgatatct ccacttttac tcctgggaca aaagtatacg gattagtcaa
    25621 tctaggtggt tatgccgaat atgctgtgat gcctgccgat cgtgcaatcc ttctccctga
    25681 tacgctagac tatgtttctg ctgctggaat ctcagaagtt tttttgactg cttatcaaac
    25741 actttactgg cttggaaaat tacaagaagg cgaaactgtc ttgatccatg caggagcaag
    25801 tggtgtggga acagcagcga tccaattagc tagacagctt tctcacgcga aaatcatcgt
    25861 tactgcagga tcagaagaaa aactcgcctt ttgtaaagaa cttggtgcag atgaattgat
    25921 caactataaa aaacaagact ttcaagaaga ggtacgaaaa atcactgaag gtcggggagt
    25981 cgatgttatt ttggatttca tcggcgcttc ttactgggaa aagaatttag cttctatagc
    26041 cgttgatgga cgttgggtct tgattggtat gctaggtggg accatcgtgc ctgagataga
    26101 ccttggtgta ttgattggga aacgtgtcca actgcttggt acattattga cacctagaag
    26161 tgatcagtat aaagcagagc tcgcacaaac ttttatgcaa aaagctgggc cttttctaga
    26221 aaatggcaag attcggccaa tcattgaccg tacattccaa ttcagcgcag tcaaacaagc
    26281 gcatgaatat atggaagcaa acaaaaacat cggaaaaatc attttgaaga taactgaata
    26341 aaatcatgct gatcaaaaaa gaggctggga cagaagcgtt taactccaag aaataagaag
    26401 aaattcacga aaattgcttt tcaaattttt gtgaatttca gcttatttcc gaaggaattt
    26461 cttctgcttc cgccgtttat acgtgtttag agcgtgagac aaaagtgttc tttacttttg
    26521 tcccacgctc tttttccgaa taaacggtgt tcaaaagctt gcatctgcgg taataagtcc
    26581 aaccaagtta aaaacataag aag
//
LOCUS       DADLIO010000034        26583 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.034, whole genome shotgun sequence.
ACCESSION   DADLIO010000034 DADLIO010000000
VERSION     DADLIO010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26583
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.034"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            172..516
                     /locus_tag="JOX41_001569"
     CDS             172..516
                     /locus_tag="JOX41_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HAY6449316.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            517..936
                     /locus_tag="JOX41_001570"
                     /pseudo
     CDS             517..936
                     /locus_tag="JOX41_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631898.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
     gene            complement(1028..1378)
                     /locus_tag="JOX41_001571"
     CDS             complement(1028..1378)
                     /locus_tag="JOX41_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449317.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1344..2675)
                     /locus_tag="JOX41_001572"
     CDS             complement(1344..2675)
                     /locus_tag="JOX41_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HAY6449318.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            2931..3497
                     /locus_tag="JOX41_001573"
     CDS             2931..3497
                     /locus_tag="JOX41_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAY6449319.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3642..3729
                     /locus_tag="JOX41_001574"
     tRNA            3642..3729
                     /locus_tag="JOX41_001574"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3674..3676,aa:Ser,seq:cga)
     gene            4063..5037
                     /locus_tag="JOX41_001575"
     CDS             4063..5037
                     /locus_tag="JOX41_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase family protein"
                     /protein_id="HAY6449320.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGERKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
     gene            5362..7257
                     /gene="asnB"
                     /locus_tag="JOX41_001576"
     CDS             5362..7257
                     /gene="asnB"
                     /locus_tag="JOX41_001576"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HAY6449321.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEKWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(7452..7898)
                     /locus_tag="JOX41_001577"
     CDS             complement(7452..7898)
                     /locus_tag="JOX41_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HAY6449322.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            8126..8275
                     /gene="rpmG"
                     /locus_tag="JOX41_001578"
     CDS             8126..8275
                     /gene="rpmG"
                     /locus_tag="JOX41_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAY6449323.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            8363..8881
                     /locus_tag="JOX41_001579"
     CDS             8363..8881
                     /locus_tag="JOX41_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAY6449324.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(8958..9914)
                     /locus_tag="JOX41_001580"
     CDS             complement(8958..9914)
                     /locus_tag="JOX41_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAY6449325.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            10080..10886
                     /locus_tag="JOX41_001581"
     CDS             10080..10886
                     /locus_tag="JOX41_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6449326.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            10883..11872
                     /locus_tag="JOX41_001582"
     CDS             10883..11872
                     /locus_tag="JOX41_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAY6449327.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            11869..12873
                     /locus_tag="JOX41_001583"
     CDS             11869..12873
                     /locus_tag="JOX41_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAY6449328.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILLSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            13005..13547
                     /locus_tag="JOX41_001584"
     CDS             13005..13547
                     /locus_tag="JOX41_001584"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HAY6449329.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            13567..14265
                     /locus_tag="JOX41_001585"
     CDS             13567..14265
                     /locus_tag="JOX41_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HAY6449330.1"
                     /translation="MNYQQQIKLRVWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            14286..14498
                     /locus_tag="JOX41_001586"
     CDS             14286..14498
                     /locus_tag="JOX41_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HAY6449331.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            14498..15460
                     /locus_tag="JOX41_001587"
     CDS             14498..15460
                     /locus_tag="JOX41_001587"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HAY6449332.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            15478..15873
                     /locus_tag="JOX41_001588"
     CDS             15478..15873
                     /locus_tag="JOX41_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAY6449333.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            16036..16401
                     /locus_tag="JOX41_001589"
     CDS             16036..16401
                     /locus_tag="JOX41_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HAY6449334.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            16398..18209
                     /locus_tag="JOX41_001590"
     CDS             16398..18209
                     /locus_tag="JOX41_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HAY6449335.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTNENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(18271..18438)
                     /locus_tag="JOX41_001591"
     CDS             complement(18271..18438)
                     /locus_tag="JOX41_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HAY6449336.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            18686..19675
                     /gene="galE"
                     /locus_tag="JOX41_001592"
     CDS             18686..19675
                     /gene="galE"
                     /locus_tag="JOX41_001592"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HAY6449337.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            19687..21171
                     /gene="galT"
                     /locus_tag="JOX41_001593"
     CDS             19687..21171
                     /gene="galT"
                     /locus_tag="JOX41_001593"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HAY6449338.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            21195..22175
                     /locus_tag="JOX41_001594"
     CDS             21195..22175
                     /locus_tag="JOX41_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAY6449339.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            22264..23088
                     /gene="tsaB"
                     /locus_tag="JOX41_001595"
     CDS             22264..23088
                     /gene="tsaB"
                     /locus_tag="JOX41_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HAY6449340.1"
                     /translation="MYYCTSFAFGIFILRIKKYATMEGENVIAERIKYMITLGIDTAN
                     QTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAIDQLFADLQISPKDIDRIAVSDGPGS
                     YTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAANCIGVDNIIVPMFDARRKNVYAGAY
                     RWKENRLETVLEDVHISASDLFTQLQKLNEAIYFVGSDCHKFFSEIKEILPSAMINTV
                     PAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKRVEAEEKWLETHTPGDESYVEKI"
     gene            23072..23614
                     /gene="rimI"
                     /locus_tag="JOX41_001596"
     CDS             23072..23614
                     /gene="rimI"
                     /locus_tag="JOX41_001596"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HAY6449341.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            23621..24085
                     /gene="rimI"
                     /locus_tag="JOX41_001597"
     CDS             23621..24085
                     /gene="rimI"
                     /locus_tag="JOX41_001597"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HAY6449342.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            24082..25098
                     /gene="tsaD"
                     /locus_tag="JOX41_001598"
     CDS             24082..25098
                     /gene="tsaD"
                     /locus_tag="JOX41_001598"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HAY6449343.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(25707..26408)
                     /locus_tag="JOX41_001599"
     CDS             complement(25707..26408)
                     /locus_tag="JOX41_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAY6449344.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
BASE COUNT         8601 a         4543 c         5539 g         7900 t
ORIGIN      
        1 ataaaaaaag cgttagcaac tatgcttaaa aagcatatcg actgaataaa ctaagcattg
       61 gacaggctga aagactacat ttaaaatgaa atgcgaagaa acaatagaaa ataaagttgc
      121 cttagaacca tagttgaatc acctaacagt cgtgaaggga gaataagaga aatggcagaa
      181 aaacaaaccg caggacgaga tcaattagga gattttgcac caaaatttgc agaattgaat
      241 gatgatgttt tatttggaca agtatggtcc agagaagaat tatctgctca tcagcgtagt
      301 atcatcacca tatctgcatt aatttcagga ggaaattttg aacaattgcc agctcatctg
      361 aagattggca agcaaaatgg cattactagt gaagaaatag cagaaatcat tacccattta
      421 gctttttatg taggatggcc aaaagcttgg tcagctttta gtttagcaaa agaaatctat
      481 ttagaagaaa atagcgaaga taagaaagag gcgtaaatga cgacaaaaca cgaagaaata
      541 cacaatggcg tgatttttcc agcaggtgaa aaaaacgaag cttacgctca agtatttacc
      601 gggtaaagct atctgaatat gttagtgaat gatcccgaag tttctgttgg tgtaggtaat
      661 gtaacttttg aaccaggttg tcgcaatcac tggcatgtcc ataaagacgg ctatcaaatc
      721 ttacttgtga ccggaggaga aggctggtat caggaagaag gaaagccagc aagacgatta
      781 atggctggag atgtcgtcgt aacgcacaaa gggattaaac attggcatgg tgcgacaaaa
      841 gacagttggt ttgaacattt ggcgatcact gctggtaatt cagagttttt agaacctgta
      901 acagatgaag tgtatgaagg attggaaaat caataatgtc aagcttgaac agctcctgaa
      961 agtagatttt aatcgaactt tcaggagctg cttttttgat tcagtctttt ataaatagaa
     1021 aatagggtta ataataggaa tgagaagcac gtcgaaagat cttaatattg ataatcggct
     1081 gggcatacat gatttccacg tcatcaatca aactacctaa cagatgataa tcttcccgat
     1141 catgtcgggg attacctaat agttcttgat aatagatttc catactaggg tcccgaggat
     1201 tgttcagcaa atcagcaagt acatctaaat cttctggctg agtttctgcc gtaccctgta
     1261 tctctatgaa aagcccttcc tcagcaaatt ctactccaat acgtatttca gttatttcat
     1321 gggaatataa ataagtaaga agctcatcga tgattctttt tgataattct ttttccaagt
     1381 gtcttttttt cctttctgac agcggtaaag ttatctagta tcggtacaag gatacctgca
     1441 acgaaaccag ttgaaaaacc actgttatat agatttagtc ctccgtgcaa agtgctgacg
     1501 ttatggacaa gagcaatatg tagtacacca gctattacac cgtaaaaact gccgtaaaaa
     1561 ccgcttatgg gcgcgagacc tgtcccaaac acagctgcaa caagcatgcc agtactggtg
     1621 atctcatgaa aagttccaaa caaagaagca ataaatattc cgactagtat cggaaaactg
     1681 ttttttaaat gacaaccaaa agcactgaaa cccaccgcag ataaaatagc accgatgaca
     1741 ggtccattta actgaccgcc aaccagcaaa acataagaag acagcatcag accaactaag
     1801 cctatgttga tcaaagtagc accaatacca gaattagcaa tgaaatcagt tgtcaatttt
     1861 ccagatgaat cgaaaatttc tcgaatcccc aaaagccgaa aggaattata atagaaacca
     1921 attccgactg tcagcgaaaa aaagccaaaa ataatccaaa tgagaggaaa gtgatattca
     1981 ttgaaaacca atgtattttc gacgattgaa tagctgaata acctcaaaac agcagtaaaa
     2041 gtcatcgcaa tcaacccaga ggtgaatcca atattataaa gtgtgaatcc acgatggaaa
     2101 actaaagttt gagcagctaa gggcggaaga agtagaccaa ttgctatgcc agctaaattc
     2161 cccaataaaa tacctatcag taaaggaaaa cgcataccaa aagtgatata actaacgacc
     2221 ggtgataatg cgctaccaaa cagtccgatc atgatgtact gagaaaaagg tttattgaca
     2281 aatacagcgt atagatacac acctaaaatg attgagatag aattataaag gtttttgcca
     2341 aaaaaagaga aaccggtaac tgttagaatc gaagcaaata agggaccgtt taaaatcacc
     2401 ttgtgccgat aagctaaaag cacagaaagt aaggtcaaaa tccctacatt tatgaatgcg
     2461 cttccgaaac cgcctaaagc aaaataatct gtcaaaagat tgcttggcga ggtaagaata
     2521 gttagcaatc cactccaatt atcagtagga gtattagaaa gcaagccaat aaaaagaaaa
     2581 aaaacacctg taaaaccaag ataaaaatac tttcttttct gtgaaacgat tcgtttttga
     2641 ggatgaatat aaataacgtc agtttcgttt tccattacac accttctttt tcattttctt
     2701 taactataac ttgaaatgaa agatttggac aactatcatt taggtcaaaa ctaaaaatgt
     2761 aagggaaccc attgaattta accaaatttt tttaattttg caaaaaaaag ttaaagaaga
     2821 ctgaaaaaaa atttaaaata taacgttttg agtaaaatgt ttgcaaaaaa tgctaaaaat
     2881 agggtacaat aaaacaacat atactgcagt aaagaagtgg gggagtttta atgagaagaa
     2941 aagtctatac caaggatcaa attctaaaag ctgcttatga tgttgttgca aaggaagggt
     3001 ttaaaggatt tactgcgaga aatattgcta aaaagatggg gatttcgaca cagccgattt
     3061 atctggaatt caaaaacatg gaagatttaa aaaatacgtt gctggattct atctttgaac
     3121 aactaaaaga agatgttttc cctattgaac gtactggtga taaaatcatt gatctcggtt
     3181 tgaactatat ctactttgca aaaaagcatc atagtcttta catggcattg tacattgatg
     3241 aacatgggga cggaaagaaa atgcatgatt tttcatacaa ttatttccgt gaaatagtta
     3301 aagaagatga aagatacaat caattatcgg atgaatatgt cgatgctctg catactggta
     3361 catgggtagc agtgactggc ttagcgtcat tgatgtcatc aaacatcatg catccaacag
     3421 aagaacaaat cattgcactg atcaaacgga caattgactc gattttagca ttagataatc
     3481 ctgaaataat cagatagtgt tctatcagta tgaatttgat cggtaagtcc gttggctgca
     3541 aactgtcaat ggactttttt gctaaaaaaa gcgatttctg ttatttatct attagaaata
     3601 ggcttgacat ttcgtgaaaa aagtttaaaa atagtactta cggaaggttg gcagagtggt
     3661 aatgcaccgg actcgaaatc cggcgaaccg gctaataccg gcgcgcaggt tcaaatcctg
     3721 taccttcctt atatcaaaga ttagaggttg tgaagaagct gtcctgcatc aagtaataag
     3781 aacggccaaa caaaaatagc ttttcctatt ttttcgtttg attgggctta ttaccgcaga
     3841 tgcaagcttt tgaacaccgt ttgttcggaa taaggggctg tgacaagact tttgtcacag
     3901 ccccttattg ttgtactttt aacctacaat attttttgat tccccctgag tactattttt
     3961 tataaatgct agtaaatcaa tcttctttgg cctttttttg ataaaaaaaa tactagatgt
     4021 aagataaaag tgtaaaaacg atttgtttta ggaggggaaa cgatgtgtac cgcaatcact
     4081 tatgcaacga aagaccatta ttttggaagg aattttgatt atgagatgtc ttataatgaa
     4141 gtggtcacta ttactccaag aaattatcgt ttcgatttta gaaaggtaaa aaatttagat
     4201 aaacattatg caatgatagg aatagcagct ggggtatcca actatccact ctattatgag
     4261 gctacaaatg aaaaagggtt gagtatggca ggactgaatt ttcctggcaa tgctgattat
     4321 aaagaattac aagaaggaaa agataacgtt gcaccatttg agtttattcc atggatacta
     4381 gggcaatgct caaccataga cgaagctaaa gaattattgg ctactatcaa tctagtcaat
     4441 atcgatttta gtgaaaaact acccttgtca cctttacact ggttattagc tgataaagaa
     4501 aaatcgatag taattgaaag tatgaaagat ggacttcatt tatatgataa tcctgtcggt
     4561 gtgttgacaa ataatccgcc atttgattat caattattta atctgaacaa ttatcgctcg
     4621 ctatcaaatg gaacaccaga aaatcatttt tcaaaccaga tcagcttgaa tgtttatagt
     4681 cgtgggatgg gaggattggg cttacctgga gatctctctt ctgtttctcg atttgtaaaa
     4741 gccacattta ctaaaatgaa tgctgcatca ggtgattcag aatctgaaag tatcagtcaa
     4801 ttttttcata tactaggctc agtcgagcaa caaaaaggag tatgcgatac tggagaaaga
     4861 aaatacgaat atacgattta ttcttcttgc tgtaacgttg ataaagggat ttattattat
     4921 cgtacgtatg aagacagtca aattactgct gtaaatatga ataaagaaga cttggatcgt
     4981 catgaattgg tcagttatcc agtcataaaa gagcaacaga taaactatgt caattaatta
     5041 atgaatagat ccgtttggta tcatattttc tgatacagtc ataattagac acgatcttta
     5101 ggtcgtgtct ttttttgctg gtttttttgg aaatagcatc cactaatatt tttttaacac
     5161 gaagagaata aggtagcctc aaaaaagaaa acatggtaaa ttagatattg ggactttatt
     5221 ttctgtaaaa acagaaactt tcatcttttg ttttcacgtg acgaaattgt aagagagaaa
     5281 atattcgtcc gctatttatt ctatgataag atgcatatga atgaaataaa cagtaatttt
     5341 atattaggat gtgaaagtta aatgtgcggt attgtaggtt ttgttaacga caaggacaac
     5401 aaaaaaacaa ttattaatac aatgatggat cgaatcgttc accgtggacc taatagttca
     5461 ggagaatata tcgataaaca tgttgcttta ggattcagaa gattaagtat tattgactta
     5521 gagggcggta ctcagcctat ttacaatgaa gatcggacaa agatcattat ttttaatggc
     5581 gaaatctata attaccagcc tttgagagaa gaattgattg cagctggcca cgtttttcaa
     5641 acacatgcag atacagaagt ccttttgcat ggttacgaag aatggggaac agaattattg
     5701 caaaagatcc gcggaatgtt tgcttttgct atttgggata atgaaaagaa tgagttattc
     5761 ggtgcaagag accactttgg gatcaaacca tattattatg cagaaatgaa cggaacattt
     5821 atgtttggtt cagaaatcaa aagttttctg cctcatcctg attttaacaa agaattgaac
     5881 aaagaagcgt tgaaacctta tatgactttc caatattctc cattaaacgg cgaaacattc
     5941 ttcaaagatg tctatcgttt gcctgaaggc cattattata cgtataaaga tggaaaaata
     6001 gacattcagc aatattggga tgcagatttt gaaacaaaag aaacgcattc ccgacaagaa
     6061 tggatcgaaa aaatcgacga aaccgttcaa gcttctattg aagcacatac ggtcagtgat
     6121 gtagaagttg gttctttctt atccagcggg gttgattcca gttatgtaac ctctgtattg
     6181 aaaccagatc attctttctc aatcgggttt gatgataaaa cctataatga agcgattgaa
     6241 gccagaaaac taaccgaact attggactta gataatacag cagcagtgat cgacggagac
     6301 atgtcgttca aagcattccc tttgatccag tatcacttag atgaacctga ttcaaatcct
     6361 tcttgcgtac ctttgtactt tttagcaaat cttgcttcac aaagtgtgcg ggtagtccaa
     6421 tctggagaag gggcggatga actgtttgcg ggataccaaa cgtatggatt ccatacgaat
     6481 tcaaaattca tccgtgtgat tgctcaagga ttgaaaaaat taccaaaagg aacacgctat
     6541 aatttaggac gtaaaatcgg aaaaatgaaa aatttccatg gacggatcca tttatatgaa
     6601 tcacttgctc ctgcaaaaga atattttatc ggtcatgctc gagtgttcga agaatcagaa
     6661 gcatcagaag tgttaacacc aaaatatcaa acagcaccat ctgtggatga aatcatgact
     6721 gttcattacg agaaaacaga aggaatcaaa gatgaagtca ataagatgca atatgtcgat
     6781 cttcatcaat ggatgccaaa agatatcttg ttaaaggcag ataaactttc tatggcaagt
     6841 tctttggaag tccgagtacc tttattggat atcgaagtca tgaaattggc tcaacaaata
     6901 ccaagtaagt ttttattgaa tcaaaacaac acaaaagata ttttcagaca agctgcgaac
     6961 aaacatcttc cggaaaaatg gtcgaatcgt gtgaaattag gattccctgt gccaatcaaa
     7021 gcttggttga aagaagaaca cggctacgaa caagtcaaag cattgttcga agcagatttt
     7081 gcaaaagaat tttttgatca agaaaaaatc atgaagttgc tagatgacca tcacgaagga
     7141 cgtaaagaag agcaaagaaa aatctggaca atcttcagtt tcttgacatg gtataaagtc
     7201 tactttgtag atgaaacgat tccgcaagca gaagcaatcg actatgtgac tgtttgatga
     7261 aaatcaaata tcaataaaaa agaggttttc tcctaccgtt taacactgag tgataagaaa
     7321 caatttcaaa aaacagctct tcccgtttta tagatattat gacttatggt tcggagttgg
     7381 cagaggaaca ccattgtttc gaacataagg gggttgtgac acgattttcg tcacaacccc
     7441 tttacatatg ttcaataatc gatttctttt tcttttgtcc catctttttt ataaatgaac
     7501 aaagttgatt ctttgttttg tgctacttgc tttccttttt cgattgcttc tttttttgta
     7561 tcaaaatggt tgcttgcctt ttttgcccct ttagatttca cgatccattg ttcttcctca
     7621 tattctacga tcacatctga atcaagcagt tttccagcac gaggattcgt atcgtgttca
     7681 tccgtcttgc ttggattttt ttctttttcg aaagttcgtt tttctgattc actagcatct
     7741 tcataccatt tttttgcttg atcaatggca attgggatcg cacggttatc agggtaccct
     7801 tcatctaata atgcatttgc gatgtcgatt gctttttttc ttgtcaattt atctaagttt
     7861 ttcattgatg caggaaagtc cttcatgttc catggcatat tagtatcccc ctttattaaa
     7921 aaacataatc tatataaaca agtgtaaggg tatttataca aaaagaaaaa gattttgttt
     7981 gagaagtaaa accgttgtat ttatcgtcaa gtagttttac ttaacaaaat cgtgaaaaac
     8041 actagcaatc tagaaaaaat catggtaaga taatcaagtc tgagagtcat cttagaggat
     8101 tcttgtaaaa atgggaggga aaaacatgcg cgtaaacatc actttagagt gtacttcttg
     8161 taaagaacgt aactatctaa caagcaaaaa caaacgtaac aatcctgatc gtttggaaaa
     8221 acaaaaatat tgcccacgcg aacgcaaagt tactttgcac cgtgaaacaa aataatgttt
     8281 ttaaagttct caattccttg ctggtcaaag aattgagact ttttttatct caaaacatct
     8341 aaaatcataa ggagcggata atatgtttat ttccatgtgg gcacaagata aaaatggtct
     8401 gatcggcaaa aatggtttgt taccatggcg attgccaaat gatatgcgtt tctttcgcga
     8461 acatacaatg gatcgaattt tagtgatggg aagaaagacc tatgaaggaa tgggggatct
     8521 ttcacttcct tatcgccata tcatcgtgtt gacaacgcag ccaaattttc gcacgaaaga
     8581 aaatgcggaa gtaatgcatt cgatcgatga acttttgtcg tatagtcaaa cgatctcaga
     8641 agatatctat gtttcgggtg gtagtcggat ttttcaagaa cttcttcctt acactggtcg
     8701 gatctggcga acattgatcg atagcacgtt tgaaggcgat acgtatattg ggaatattga
     8761 tttttcagac ttcgccctta tagaggagta tgaggggata acggatcaag aaaatctata
     8821 tgcccatcgt tttcaaaaat gggaaagagt aaaaaatagg gttgcttcaa aagaagaata
     8881 aaatctatgc gtctagtttg ttaataagaa aaaaagcata tcacgactaa tcgtgaagat
     8941 gcttttttta gttaaaatca atttagtttt tctttgatat cattgaccat ttcctgactg
     9001 gcaataggtc cgttatatag ccaactagat tcaggtccga attgcagtac atgattgtct
     9061 gtcactgctt taagattctt ccagcttggt tcattgaaca tggcagcatc tttgtcactg
     9121 ttcacaagga tgatgtagtc agcatctaat tcagctagct tttcagagga aacagcagac
     9181 cagtcagaag tggctttttt ggagacctct tccactagat caggaacacc aaattccaga
     9241 tcgtcgtata cgattcttcc acttgaccga tttttgctga ccataaaggc tgagttgttg
     9301 gtcacccaca acactgcagc tgtcttgttc tcgattttat ctgctagttc ttctcgagtt
     9361 ttcttgatgg atttttgata atcggaaatg atcttttctg cctctttttc ttttgccaaa
     9421 gctttgccga catcttttag ttgttcttcc catgtgacat ctgttccgtt ttttacaaca
     9481 taagttggcg cgattttgct atattgttcg tatttcccgc cttcgacagt agcggaagaa
     9541 gaaatcaaca gcaaatcagg ctcaaagctt aacactttct cataaggaag gtcataagaa
     9601 atcgttggga catcctttaa atcatcttgc agataatctt gaatggaacc actgccaaca
     9661 gtccactggg cgataggttt ttcccctagt gcaatcagat agtcttctaa gtaactgccg
     9721 atgatccgtt tgggcgcgtt tggaatctct actttatgtc caagtgtatc tgtgactgta
     9781 tgagtactat tggatgaagt cgtcgaattg gcagttgtag ctgtttcttt atctgaagag
     9841 ggggagcaag cgctcagtac tccagccagc agcaatatgc tagataatgt gaatactttt
     9901 gtttttaatt tcatttcttt cctcctaaca taattgagaa tctttctcat tggttattat
     9961 tcctgatatt tcgaacgctg tcaaccgctt catttggcta tagatatgaa agtagcgctt
    10021 gacgaaatgt tgaaacagcg tcataattga gaatgatttt cagcgaaagg atgggtgaaa
    10081 tgacgagatt aagagcagct gacattgcag ccggctacga aaacaaaaaa atcattgaaa
    10141 acatgtctgt tacgattcct gaagggaaaa tcactagttt gattgggcca aatggaagtg
    10201 gaaaatctac tttattgaaa agttttaccc gtatactacc tgtgaaatca ggaaagatca
    10261 ttgtcaataa ctctgatatc tctacataca gttcaaaaga acttgcaaaa aaaattgcat
    10321 tattagcaca aactagtgaa caccctacag gtatgacagt agaagaagta gtatcttacg
    10381 gacgataccc ttatcaaaaa ctgttcagtg gcatggacac gcaagatcat gaagcaatcg
    10441 agtgggcgtt ggatgctaca ggtctagctg gatttcgtat gcgggatatc gcaacgctgt
    10501 ctggtggaca aacccagcgt gtctggatcg ctatggcgct tgctcaggaa acagatatct
    10561 tgatcttgga tgaaccgaca acatttttag atccggcaca ccaattagag atcctacagt
    10621 tattgactga aatcaatcaa atgaaacaaa caacgatctt gatgtcgatt catgacatta
    10681 atcatgcttc acgtttttca gattatttat tagcaatgaa aaacggtaag ttgatcacag
    10741 aaggtacacc tgaagaagtg atcacaaaag agtgtatgaa aaaaatattt gagattgatg
    10801 caacgattgt cacgcttcca agaacaaata aaccagtttt tctaacctat gatttgttgc
    10861 caaaagagca ggaggatcaa ttatgaggac tatgaagaaa aatagactcc tgcttttggt
    10921 ctgttttgtt cttttgatta ttttttttgt tgctctttca aatggcgcag cgactgtggg
    10981 aaaagcagat ttttggcagg cgttgtttga ttttgataga tcaaaacaaa gtcaccaaat
    11041 catacgaaat attcgtttgc ctcgtgtggc gggagcattt cttgtaggga gttgttttgc
    11101 attgagcggt gcattgatgc aaggagtgac aagaaatcct ttagcagatt caggcttact
    11161 aggaatcaac gcgggtgctt cgttggcaat ggcccttagt tttgcttttt ggcctaaagc
    11221 ttctgatttt tctgtgtttc taatgtcatt ggcaggttct tttgctgtaa ctttgctcgt
    11281 atttggtttt ttgcagtttt cgaaaatggg catgaatcct ttacagctga ttttagctgg
    11341 cgtagctatt agttcttttt ttactgctat cagccaagca cttacccaat tctttaatct
    11401 gcagcaggat cttgcttttt ggtttgtagg cggagctgcc aatatcacat ggaaacaatt
    11461 agcagtattg tttcctttat atatacttgc tgttttggtt tctttttcat taggaaaagc
    11521 aatatctttg attcatttga gtgaaacaca tgcattagct cttggaagtc atcctaaacg
    11581 aacgcggttg attgttttct gtctagttgc agtgttagca gccattgccg tttcgttagt
    11641 cggacctgtt tcatttattg ggctgttggt tccgccagtt gttcgcggaa tggttggaac
    11701 ggactatcgt tatgttctac ctgtctcttt tttagttggc ggtggattgg ttatgttggc
    11761 ggattttaca gcgaggatga tcaatccccc ttttgaaaca ccttttggat tagtcattgc
    11821 attgattggc gttccgtttt tactgataca agtaaggagg gaacaacggt gaaaaaaata
    11881 tattggacgt tctatttctt gctttttgta cttgtcatcc tgtctatagg tagtttaatg
    11941 attggtacgc cttttattta cctggatcag ctttttgcca cgttcatagg gaaagaatca
    12001 tcttctttgg cgctgattgt tagagaattt cgagttcctc gattactgat cagtttatta
    12061 gcaggagctt gtcttggcgt ttctggttat atcttgcaag gagtaacaag aaatgaattg
    12121 gcagattcta gtatattggg cattaatgcc ggagcaggat ttttagtgat gctttattta
    12181 ggtttctttt cgcactattc gctgccgttt ctattgctag ttgtagcctt tctaggtggt
    12241 gttttagctg cttgctgtgt ctatcttgcg gcctatgatc gaaatggctt tttgggtatg
    12301 aatcgaatct tattgtccgg tattgccgtt aatgccggcc tttctgcatt aacattgcta
    12361 tgcacgatcc aattatctaa ggaaaattat ggatttgtga atgcatggtt agcgggatca
    12421 atctggggtg cgagctggcc ttatgtttgg gcattgcttc catgggcggt tatcttaatt
    12481 ccgctaggag gactttatgc acagaggatt gtattgctat catttggtca agaacgcgcg
    12541 caaggattag gccttaacgt ggctaaaagt caaaaaatcc ttttgttgtt agctgttgct
    12601 ttggcaagcg gtagtgtagc ggtgacaggt agtttatctt ttgtaggact actagctcct
    12661 catgctgcga agctagtcgt acgtaaagaa aataactgga cctttgttct gagcggtttg
    12721 ttcggttcca tttttctgct tagtgcagat atggttgcta gagtgattct actaagtggg
    12781 gaagtaccta caggaatttt gattgccctt tttggtgcgc catattttct gtatgcactt
    12841 tttatcagac aaaaacacgc gctgaacagt tgaaattcat taaaaaagga aggccaatca
    12901 tttctaggtc ttctttttat tctatttatg catttatttg aaagttcgat tgctattttt
    12961 ctttttttcc tataccattt tatgagagaa ggaagggtga gtttttggac caattgaaag
    13021 taagattacg ccggaaagga atcgaaaagc tgaaaaatct ggccaaaagt ggcaagaaaa
    13081 aggaaaaaga acagcgaatc tataaacagc tattcgccag cgagtactgg aagtcagcaa
    13141 aagtgatagg gacgacttta tcgaatgaat ttgaactgga tacacagccg gttatccaac
    13201 gagcagaaaa agaacaaaag aaaatagttg tacctaaaac tttgccgaaa cgtcagatgg
    13261 cgttttatga aatggatgaa cagtccgttc ttgtacgttc gagttttggt gttcttgagc
    13321 cacaatcaga gaagctctat ttgccggaga tgatcgatct cctcattgta ccaggtatta
    13381 tctacaatag agccggttat cgaatcggtt ttggcggtgg ttattacgac cggtatttaa
    13441 ataattttca taaaaaaaca tgtagccttg tttttcgtga acaattgaat gaacaatggc
    13501 aaccggagag ctttgatcag aagatccaac aattgtttat tgactaaaat gaaatgggag
    13561 gttttcatga attatcaaca gcaaataaaa ttgcgtgtat ggttaagacg accgttatgg
    13621 acctatgctt ttttagggat acagacagcg gtcttcctca tgatggaatt atttccgcga
    13681 cttgagatcc cttattatgc cggaatgtat ggtccttatc ttgttcactt caatgaatgg
    13741 tggcgtttag tgacaccaat cttcatccat tttggactga tgcatttcgt aatgaactca
    13801 ctgatactgt attttatggg gcagcaaatc gaggcaatct atggccattg gcgttttttc
    13861 ttgatttata tgttcagcgg gataatggga aatacagcaa gctttgcttt taacgaagcg
    13921 aatgttctgt ctggtggtgc aagtacttcg atattcggtt tgttcggtgc gttgtttatc
    13981 ttagggtttc attttaaaca taacccagcg atccagcagc tagtcagaca ttttctttta
    14041 tttattgtgt tgacatttgt ttttggtctt ctggatacct ctgtagatgt ttggggacat
    14101 gtcggtgggc taattggcgg attagtgtta gggaatgttt tgggtctacc gaaacaacag
    14161 acaagctatt cgatacacca aaggattctt tctacactag tttttgtatt tctttttgta
    14221 atatgtattt tactgggttt aaaaaaatat ggtttacttg tataatatga aggaagtgct
    14281 taaagatgga gagcttatat gatgtacagc agctgttcaa aaaatttggc atctttatct
    14341 atgtgggtgc acgcatctat gacattgaat taatgactat cgaattgcgt aatctgtatg
    14401 atagccgttt gattgatcat gatacataca tgacagcgtg gcgcatatta aaaagagagc
    14461 accgaattga agaaagccga aagaaaggaa atttgtaatg gacaagaaga ttattgggat
    14521 tgatttaggt ggaacaacag caaaatttgc aattttaaca ccagaaggag agattcagca
    14581 aaaatggagc atcgatacca atattttgga tgatggtaag catatcgttc ctgaaatcat
    14641 tgaatcaatc aatcatcgtt tgaatttata taatatgaaa gccgaagact ttatcggaat
    14701 cggcatgggt accccaggaa gcgtggacag cgaagctgga acggttattg gtgcgtataa
    14761 cttaaactgg acagaagttc aatttgtgaa aaaactgatc gaggcaggaa caggaatcaa
    14821 attcgctatc gataatgacg cgaatgttgc tgctttaggt gaacgatgga aaggtgctgg
    14881 agaaaacgat ccagacgttg tattcgttac tctaggaaca ggtgttggcg gaggtatcgt
    14941 tgctggcgga aatttgattc acggcgtgag cggagctgga ggagaaatcg gacatatcac
    15001 tgtggatcct gaagggttcg aatgtacttg cggtaaacgc ggatgtttag aaactgtatc
    15061 tagcgctaca ggtgtggtac gcctaggtcg tttcttggca gaagaatacg caggggattc
    15121 aaaactgaaa gcaatgctag acaacggaga agaagtaaca agtaaagata tctttgaaat
    15181 ggctcaagaa gacgatccgt ttgcattgat ggttgttgat cgcgtatgct tctacttagg
    15241 tttagcttgc ggaaacttgg ggaatacatt aaatccgtca agtatcgtgt taggtggagg
    15301 agtatcggca gcaggagaat ttttacgtag ccgtgtagag aaatatttta aagaatttac
    15361 tttcccgcaa gtaagagaat caacaaaaat caaattagca gagcttggta atgaagctgg
    15421 tgtcattggt gctgcctcat tagccttgaa atttgcttaa aaaaacggag gcattacatg
    15481 gttttatggg taattaatat cattttgcta ttgattgtgc ttgcaatcat cctttgggaa
    15541 gtctatctac gagtaatggc caaacgttca gcaacgactt tgacagaaga agaatttcga
    15601 gaaggaatga gaaaagcaca agtaatcgat gttcgcgaaa aagatgtgtt tgatgctggg
    15661 catattttag gtgcaagaaa catcccttac actgttttga aagattcatt aggatctatt
    15721 cgaaaagacc agcctgtcta tatttacgat caaaagaaaa gtttgagcat ccgtacagca
    15781 aataaattac gtaaagcagg ttatcaagag atttatttac ttaagggtgg atatgacgga
    15841 tggtctggaa aaatcaaaag taaaaaagta taaaacagat gattgtatga cagctttaaa
    15901 aaccgaatca atcattagat tttgaccaag atcacatgaa cggcgcaatg gatagttgtg
    15961 ccgttcattt tttttatttt gtgctattat ctacatatat aagctaagcg aaaaggtaga
    16021 aagaaggaaa caactatgat caaattaaaa cgtgtttacc ttgatgctga aaaagaggat
    16081 ggctatagaa tactcgtgga tagattctgg ccacgaggaa tttcaaaaga aaaagcgcag
    16141 ttagatctgt ggttgaaaga aattgcacct agtaatgaag cacgcaaaac ttttgaccat
    16201 gtaccagaac gatttgcttc atttgcaaag aaataccagc aagaattgat tttcgaagaa
    16261 gaaaagaagc aagctatttt taaactcagt caacttatga aagaacatcc agtcattact
    16321 tttgtttatg gtgcaaaaaa tgaacatcag aaccatgctg ttttattgaa aaaatttatc
    16381 gaaatggagg catgcaaatg aaaataggga tcattggtgc cggacctaga ggattaagtg
    16441 tagcagaaag gattctccat aataatcagg acagacattc tcttgaactt tttcttttcg
    16501 atcccaatgg tcctggaggt cgagtttggc ggttgaatca gccaccggag ttattaatga
    16561 attctgtttc tcaacaagtg acgcttttta cagatgaaac attgtccagt ggaggattgg
    16621 taacacaggg acccaacttg tttcaatgga gtaaaggacc tgctacagat tatatcgaac
    16681 agacggtaac caaaaataag caactaatta tagaagaaat caatcgtctg gaaaaagatc
    16741 agcaatctac tcgatgttta tacggactct atcaacgctg gtttttctca aagttgcaag
    16801 aagaatttcc agcttctatt cagtttgttt attctttagt aaaaaaagta agcaaaagaa
    16861 aagatggtta tcttttacag acagatcagc aaagctattc tatcgatcag cttgttttag
    16921 caagcggtca ctgggaaaat gatgagacag aagaagaaag agtgtgggta gactacgcaa
    16981 agaaaaatgt tttactgtat cagcttcctt ctaatcctgc agatgtagat ctttcgaaga
    17041 taccgcctaa agaaaatgtc tttttaagag gtctaggctt aagttttttt gattatgtcg
    17101 gattgtttac agtatcaaga ggagggcgct tcgagaacga aaagggaaaa ctggtctatc
    17161 atccatcagg caaggaaccg attgtataca gtggatcaag aagggggctc ccttattacc
    17221 ctcgaggaag aaatcaaaag caaggcggag caatggcatg gccacggtta ctaacaaatg
    17281 aaaacctgga gcaatggcat cagtcgggat ttttgactgg cgaaacattt tttgactatc
    17341 tgaaaaaaga cgttgagttg ttttattaca agaaaatcat cgaagaatat cacttgccga
    17401 ttccaaagaa aaattttgag catgattttc tctccctctc ttcagaggag tgtctcggaa
    17461 agcatccagc actaatccct tatagatggg attggtcgta tttagaaact cctcttgcct
    17521 atcagaatga gcccttttca gaagctagcc gaatatttat tgaagggcag ataaaagaag
    17581 cggaaaaagg caattgcaca ggagcatttg cttcaacatt tgatgcatta aaagactggc
    17641 gtgatccaat ccggcaggct attgaatggc acgttttttc tgctaaggaa tacaaagaaa
    17701 tactatgggg atggtttact catctaaata gctttttaac gatcggtccg ccaatcattc
    17761 ggacgaaaga attagcagca ctgatagatg cgggtatttt tcatttgatc gaaccgccat
    17821 ttgatattca gcaaaagcac aaccgctatg ttatttctct acaagataaa gaaatcagca
    17881 gtcgctattt gattgaagct cgattgccac aaacaagctt ttctcgttca agtaatcctg
    17941 tcataaaaaa tttgaaggaa aacaaacttg ttcgcccttt ttcattttca gataatacag
    18001 gaagttatca ttcagaagct atagatgttg agcgaggtac gaatcgcgtg attgatgctt
    18061 caggggaaat ccagtctgac ttttattgct atggaatacc tgttgaaggt gtggattggc
    18121 taactgcagc agtagctaga ccttatacag atccatggaa tctgagacag gcagataaaa
    18181 tagcacaact tatattgact gacaaataaa aatacgcatg atgacttatc tgttttttag
    18241 aaagtcttca tgcgtatttt taaataatta ttaacgagaa acgcgtttac gcattgcttt
    18301 tttacggttt tcttcgatca ttgcttcttt ttcgtcaatt ggatcgatca ctgttttttt
    18361 cacagaagca accaaaccag caacggcagc ggctgttgcc agacttccta ctaatattcc
    18421 agatacaaat tttttcattg aatccacctc atttattatt tgttatatct attatggaac
    18481 aaaagagaaa aaaaggctag ttttacgttt gtttgtaaac ctttgcaaaa aatccttgaa
    18541 aatgtttact aaatgtttta ttataaattt accatatgaa tttacgaaat tttactttgt
    18601 ttgttttcac cataaaagta aacttcgttt tttaaattat atagaatcaa caaacacaat
    18661 tttactaatc aaaggagtgt tttttatgac aattttagta ctaggcggag ccggttatat
    18721 cggttcgcac gctgtagacc agctagttca aaaggggtat caagtagctg tggtagataa
    18781 tttgctcaca ggtcacaaac aagcagtaca tccagatgct catttttatg aaggagacat
    18841 ccgggataaa gaatttctac gttccgtatt tgaaaaggaa ccgattgaag gagtaatcca
    18901 ttttgctgca agctctttag taggagaatc tgtcgaaaaa ccattgatgt atttcaacaa
    18961 caacgtatac ggtatgcaaa tcttacttga agtcatgcac gagttcaacg tgaataaaat
    19021 cgtattctct tctactgcag caacttatgg agagccgaaa gagtctccaa tcacagaaga
    19081 tacaccagct aatcctaaaa atccgtatgg tgaaagtaaa ttgatgatgg aaaaaatgat
    19141 gaagtggtgt gaccaagcat atggcatgcg ctatgtcgct ttgcgctact tcaatgtagc
    19201 cggagcaaaa gcagatgcat ctatcggaga agatcataca ccagaaacgc atcttgtccc
    19261 aatcatttta caagtagctc ttggtcaaag aaaagccttg gctgtttatg gagacgatta
    19321 tgatacacca gatggaacat gtatcagaga ttatgttcaa gtagaagatt tgattgctgc
    19381 acatatttta gctttggaat acttgaaaga aggaaatgaa agcaacttct tcaatttagg
    19441 cagcagcaaa ggatactcag tcaaggaaat gctagaagca gctagagaag tgacaggaaa
    19501 agaaattcca gcagaaatag caccaagaag agctggagat cctagccgat tagtcgcttc
    19561 aagtgaaaaa gcgagagaga ttctgggctg gaaacctgaa tacacagata tcaaagcgat
    19621 tatcaaaaca gcatgggatt ggcatgtcag ccatccaaat ggttatgaag aataggggaa
    19681 tgagatatgt caatcagtca aacgatttgt gattttgcca cacttgcgat cgaagctggc
    19741 ggatggatgg aaatggaccg cttatattta cagaatcgtc ttttagggat ggtaggagaa
    19801 gatgctctag aaagcattga agtaagacca gttaaggaag aatctgtaga cttattggat
    19861 cagcttgtcg ctaaggcaag agaaaatggt gttctttcag aattgccagc agaacaagag
    19921 atttttgaag cgcaattaat ggattttctc acaccgccac cttcagtcgt caatgcattc
    19981 tttgcacagc actattcgaa aagcccagag gaagcaactg agtatttctt taatttaagt
    20041 aagaaaaatg actacatcaa aacaagagcc atcgcaaaaa acatcaaatt tccggcagag
    20101 tcggagtatg gtgaactgga aatcacaatc aatttatcta agccagaaaa agatccaaaa
    20161 caaatcgcag cagaacgcga ggcggtaaaa gtagactatc ctacctgcat gctttgcatg
    20221 gaaaacgaag gatatagagg tcgcttgaac tatccagccc gcaccaatca ccggattatt
    20281 cgaatgaatc tagacggtga aagctgggga ttccaatatt ccccttatgc ttattacaat
    20341 gaacattcga tcattttatc agaacaacac cgcccgatga aaatcacaaa ggaaacattt
    20401 gctagactgc ttcggattac tgaagtcttg cctcattact ttgttggttc gaatgctgac
    20461 ttaccaattg ttggaggatc gattctttct catgatcatt atcaggcagg acgtcatgaa
    20521 tttcctatgg caaaagcacc gatagaaaaa cttatcaaac tagaagatta tccgcaagtc
    20581 atcgcaggag tcgtgaaatg gccgatgtct gtgatccgtt tgcaatcaac agagaaaaac
    20641 ttgcttattg aagcagctaa ctcagtattg gaaaaatgga aagcatattc ggatgaaaca
    20701 gtatctatca gagctttttc agcagatggt acaccacacc atacgattac gccaattgca
    20761 cgaagaaggg acaattactt tgagttggac cttgtccttc gagacaacaa tgtttcagaa
    20821 gaacatcctg atgggatttt tcatccacat aaagatgtcc aacatatcaa aaaggagaac
    20881 attgggttga tcgaagtaat ggggcttgct gttttaccac ctcgtttgaa accagaacta
    20941 gtagaagtag agcatttctt attaggagaa gaaaaccaga tggctgaata tcatcgtccg
    21001 tgggcagaac aattaaaaaa agaacatcct gatttgacga aagatacggt caccgatgtc
    21061 gtacaaaaat ctgtaggtca ggtttttgca cgtgtactgg aagacgctgg agtattcaag
    21121 cgagatgaaa aaggacaggc agcgtttgaa cgatttactg cgattttata aacgtaaaaa
    21181 aggaggagag acaaatggca acaattaaag acattgcgca gttggcagga gtttctcctg
    21241 ctactgtttc aagagttctc aactatgatc ctgatctttc cgttggctta gccacaaagc
    21301 aaaaaatttt tgaagcagca gaacgcttaa attatacgaa acatcgtaaa aatgcagcaa
    21361 atactaagca aacgcttcgc ctgatccagt ggtacgacga tacggaagag cttgaagatc
    21421 tttattattt atctattcgc ctaggaatcg aaaaaaaggc agaagaagca aacgttactt
    21481 tattgaaaga aacgtgggat tccattagtg atcttccggc agatggaacg atcgcactag
    21541 gaaaattcga cgaagctcag ttattagaaa tgaaaggatc ccaaaatgcc ttgcttttgg
    21601 tagattctga cggcacttct caaggaatcg actctctagt tgtcgacttt aagtcaagtg
    21661 ttcaaaaagt cattgaacac tttgtctccc ataaagcgca acatatcgct atgcttgctg
    21721 gaacagaata tacgaagaaa aaccatcagc ggctaaaaga tcccagaatt atggcatttc
    21781 aacaagtttt ggcagaaaaa ggctacgacg aaggtccaat tatcgaagca gatttttctg
    21841 tcgagtcagg atatcaagca gtgaagcagt atttaaaaac gaatccgcat gttcctgatg
    21901 cgctttttgc agctaatgat gcattagcga ttggcgcact gaaagcgatt caagaaaaag
    21961 gtttagtggt accagaagat atttctgtga tgggcttcaa tgatgtcagt gtagcgaaat
    22021 atgtaacgcc ctcgctttct actgtaaaag tttataccga atggatggga gagctagcag
    22081 tggagacgat tcttcaatta agtaattcca aagcaccggt ttcaagaaag attattgtgg
    22141 aaacagagtt gattattcga gaatcaacga aataaaagat ggaaaagctg tgggaaaatg
    22201 gagtgatacc gcagcttttt tgtgtttcag gaaggggcaa aatttgcccg ccagcagata
    22261 atcatgtatt attgtactag ttttgccttt ggtattttca tcctcagaat aaaaaagtat
    22321 gctacaatgg aaggcgagaa tgtcatagca gaaaggatca aatatatgat tacattagga
    22381 atagatactg caaaccaaac tttggcgatc ggtgtggtag aagacgaaca aattcttgga
    22441 caaatacaaa caaatatcaa acgcaaccac agtgtaacac tgatgcctgc aatcgaccaa
    22501 ttgtttgcag atcttcaaat aagtccaaaa gacattgacc gaatcgcggt ttctgatggt
    22561 cccggttctt atacagggct tcgtataggt gtaacgacag caaaaacgat tgcttataca
    22621 ttagataaag agctagtagg agtatctagt ctgaaaacca tcgcggctaa ttgcatcggt
    22681 gtggataata ttattgtgcc catgtttgat gctcgaagaa aaaatgtata cgctggggca
    22741 taccgctgga aagaaaatag attagaaact gtacttgaag atgtacatat ttctgcttct
    22801 gatttgttca cacaactaca aaagctgaat gaagctattt atttcgtcgg gagtgattgt
    22861 cacaaattct tctctgaaat aaaggaaata ttgcctagtg cgatgattaa tacagttcca
    22921 gcatgggata ttccaagtgg tgtaactgtg gctcaattag gtgctttagt tgaaccagtt
    22981 gcagagaaac aagcttttct tcctcgctat ttaaaacgag tagaagcaga agaaaaatgg
    23041 ttggagacgc acacacctgg agacgaaagt tatgttgaaa aaatttagag cgtatgccag
    23101 aagctttttt caagataaaa tgatttatac agaaaaaaca gtcgaacaaa tcgatcgtcg
    23161 ttacgtacta agagaattga ctacagaaga tatcaaagag ctgctggatg tcgaacgaga
    23221 agtctataat ggcgaattgc catggacaaa aagtgccttt atatcagaat tgaagtcacc
    23281 gcttcctcat ctatatctag gtatctttga taatggaaga atgattggtt ttatcggttc
    23341 aagagcgttc ggtttagatt gccatatcac gaatattgcc gttcgaccgg catatcagcg
    23401 taaacgaatc ggttcgctgc ttattgacga aatcgagaac tttgctataa tgaatcgctg
    23461 tgagacgatg tcattagaag tgcgtatgag taatcaagat gcacaaagac tttatcggaa
    23521 attggggttt caagcaacaa cgatcaaaaa aagatattac actgaaacaa aagaagatgc
    23581 gttggatatg ataaaacttt tagaaaatga gtgagattag ttgatttgca gaaaaaaaga
    23641 ttttgatgaa gcgtacttgg cagaatgcgt atggatgatt agcgaaaatg cttatccaca
    23701 tggttcacct tggacgaaaa tgcagttttt ggcagacatc caacagcctc actctgatta
    23761 tctgctttta gctgaagata accagatctg tggctttatt ggatactcga aagtaataga
    23821 tgaagtcgag atcacaaata ttgctgttgc agtttcagaa caaggaaaag ggcatgcacg
    23881 gcatttgtta caattactga ttacggaaca aataaaagat tcgctgcatg tttttttaga
    23941 agtacgtcta tctaatgaag cagcaagaaa actttatgaa tcagaaaagt ttcgtatatt
    24001 aggtaaacgg aaatcatatt atcgcaatcc gacggaagat gcgatcatta tgagcagaaa
    24061 gttaaaaacg gagacgatga aatgaatgaa gaattgattc tggcgattga atcaagttgt
    24121 gatgaaacga gtgtagcggt cgttagaaat ggaacagaga tcttatctaa catcgttgct
    24181 tctcaaataa acagtcataa acgttttggt ggcgtagtac ctgaagtagc tagccgccat
    24241 cacgtagaac aaatcacctt atgcttggaa gatgcactgg tagaagctgg tgtgtcggca
    24301 gaagatttat cggcagtcgc tgtcacttat ggaccaggac ttgtcggctc gttgctgatt
    24361 ggtatttctg cagctaaggc ttttgcttgg gcacaccaat tgccgcttat tcctgtaaac
    24421 catatggcag ggcatatcta tgcagcccgt ctggttaaac cattccagtt tccattgatg
    24481 gcacttcttg ttagcggagg acatacagaa ttagtctata tgcaagaaga tggatcatat
    24541 gaaatcattg gggagacaag agatgacgca gcaggagaag cttatgacaa agttggaaga
    24601 gtattaggtc tttcttaccc aagcggaaaa gaaatcgatc agctagctca tcagggaaaa
    24661 gataattacc attttccgcg agcgatgatc catgaagata attatgattt cagttttagc
    24721 ggattaaaaa gtgcatttat caatttggtg cataatgcac aacagcgtgg agaagatcta
    24781 gacaaaaatg atttagcagc tagctttcaa gcaagtgtga tcgatgtatt gattactaaa
    24841 acacttcgag cttgtcaaaa ttatccagtc aagcaactga ttatagctgg aggtgtagcg
    24901 gccaatcaag ggttgcgtga aggattgcag gatgctttgg caactaaact ccctgaggta
    24961 gaactagtga ttccccctct tcgactttgt ggagataatg ctgcaatgat tggagcagca
    25021 gcacatgtgg aaatgcaaaa aagaaatttt gctagctatc agttgaatgc tgatccaagc
    25081 ttggttttat ctgaataaag aggttgtgaa aaagctgccc tgcatcaagt aataagaaca
    25141 gcccaggaaa aacggcttct catgtttttg acctggctgt tcttattacc gcgtatgcaa
    25201 gcttttgaac gccgtttaat caagagttcg taagcctgtc gtttaactct gattcacaag
    25261 gaacaatttc aaaaaacagc tcctcatgtt tatgaacatt atgacttgtg accgaagagt
    25321 tgacaggtac acaccgttta atcgaaatag ggctgtgaca cgtttttgtc aaagccctat
    25381 tttttacata cttttaatca ttattgttat tttgctattt tttacagctt atttatcatt
    25441 atccgttcct ctgattgccc tcactgagta atcgtttatt gtcgaggaat atcgaataat
    25501 ctagatcgga tgaggacaag acgcttcatc tagttaatct aacagtattt tttgcaaaca
    25561 gtgaatatta cataactgaa acacacatag aaaatctttg agtcttgtcc agtgatctaa
    25621 aactgccgga tctttcagaa gttttaggga ggaaaataag cagtgaccct gatatttatc
    25681 agggtcactg cttatttttg ttcgcgttat tctctcatag ctggagtagt agctgtctta
    25741 cagaaagtaa aacgcttttt gtcataatct aacagcccgg aatcacgtag ttgtttgatt
    25801 acttgtccag cagtttcacg tgtcgtgccg ctattcactg ctaattcttt taaggtgatc
    25861 ggataaggaa tggtgatatg accatctttt gttggtacgc ccaattcttc tttcaaaatg
    25921 aataaatttt gttttacccg gtcaaaggcg ctagaggtca atccgatttg gatacgcaat
    25981 tcatgtattt caactacttt agaaattttt tgtatcatat agatcaactg ttcgggattt
    26041 tttcgtgcta atttttcata gtaggaaaca ggaaggtaga atgtttcaat atcagtcatc
    26101 gcttgagctg tataagtgta ggtctcttct ccaaacattc ctgacatagg aaaaaggtta
    26161 tttgtattca catagtcata gtagtaataa gttgcacttt catcataacg ttctaaacga
    26221 acgagtcctt tggtcaagat atacaaccgt tgtctgggat caccatcgtc gaaaaggatc
    26281 tgtccttttt tataagaacg aagaacagta tgttccttga tctgttggaa ctcttcatcc
    26341 gagaaatgtt caaaatcagg ttgatatctg agttttgaaa agtgaaaatc gattttatta
    26401 acacgcatta aaaagtcctc tccttattgt tcactatatt tattgtcact ttttttaaag
    26461 aatttgtaaa gttttaacat accaacatta gaaacaagtt ttaatacttt acaaatataa
    26521 tttgttatta tgtaaaaaat atacaatggt attgaataat ttgttttgaa gcgaatgatt
    26581 tgt
//
LOCUS       DADLIO010000035        26105 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.035, whole genome shotgun sequence.
ACCESSION   DADLIO010000035 DADLIO010000000
VERSION     DADLIO010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26105
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.035"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(164..388)
                     /locus_tag="JOX41_001600"
     CDS             complement(164..388)
                     /locus_tag="JOX41_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HAY6449345.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(586..2166)
                     /locus_tag="JOX41_001601"
     CDS             complement(586..2166)
                     /locus_tag="JOX41_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HAY6449346.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(2567..3943)
                     /locus_tag="JOX41_001602"
     CDS             complement(2567..3943)
                     /locus_tag="JOX41_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAY6449347.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(4071..5189)
                     /locus_tag="JOX41_001603"
     CDS             complement(4071..5189)
                     /locus_tag="JOX41_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAY6449348.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            5331..5765
                     /locus_tag="JOX41_001604"
     CDS             5331..5765
                     /locus_tag="JOX41_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAY6449349.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(5843..6376)
                     /locus_tag="JOX41_001605"
     CDS             complement(5843..6376)
                     /locus_tag="JOX41_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HAY6449350.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(6470..7648)
                     /gene="mutY"
                     /locus_tag="JOX41_001606"
     CDS             complement(6470..7648)
                     /gene="mutY"
                     /locus_tag="JOX41_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HAY6449351.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(7641..8438)
                     /gene="recX"
                     /locus_tag="JOX41_001607"
     CDS             complement(7641..8438)
                     /gene="recX"
                     /locus_tag="JOX41_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HAY6449352.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            8545..9927
                     /gene="rlmD"
                     /locus_tag="JOX41_001608"
     CDS             8545..9927
                     /gene="rlmD"
                     /locus_tag="JOX41_001608"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAY6449353.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(10101..10679)
                     /locus_tag="JOX41_001609"
     CDS             complement(10101..10679)
                     /locus_tag="JOX41_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin-binding protein"
                     /protein_id="HAY6449354.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            11001..11471
                     /locus_tag="JOX41_001610"
     CDS             11001..11471
                     /locus_tag="JOX41_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HAY6449355.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(11579..12805)
                     /locus_tag="JOX41_001611"
     CDS             complement(11579..12805)
                     /locus_tag="JOX41_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HAY6449356.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(13559..13759)
                     /locus_tag="JOX41_001612"
     CDS             complement(13559..13759)
                     /locus_tag="JOX41_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAY6449357.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(13893..14501)
                     /locus_tag="JOX41_001613"
     CDS             complement(13893..14501)
                     /locus_tag="JOX41_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HAY6449358.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(14586..15056)
                     /locus_tag="JOX41_001614"
     CDS             complement(14586..15056)
                     /locus_tag="JOX41_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HAY6449359.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(15104..16018)
                     /locus_tag="JOX41_001615"
     CDS             complement(15104..16018)
                     /locus_tag="JOX41_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAY6449360.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            16164..16967
                     /locus_tag="JOX41_001616"
     CDS             16164..16967
                     /locus_tag="JOX41_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HAY6449361.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            17145..18092
                     /locus_tag="JOX41_001617"
     CDS             17145..18092
                     /locus_tag="JOX41_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HAY6449362.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(18160..18453)
                     /locus_tag="JOX41_001618"
     CDS             complement(18160..18453)
                     /locus_tag="JOX41_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HAY6449363.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(18481..19146)
                     /locus_tag="JOX41_001619"
     CDS             complement(18481..19146)
                     /locus_tag="JOX41_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HAY6449364.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(19286..19918)
                     /locus_tag="JOX41_001620"
     CDS             complement(19286..19918)
                     /locus_tag="JOX41_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAY6449365.1"
                     /translation="MIKVLLVDDHEMVRLGVSFYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(19925..20992)
                     /locus_tag="JOX41_001621"
     CDS             complement(19925..20992)
                     /locus_tag="JOX41_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAY6449366.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(20989..21720)
                     /locus_tag="JOX41_001622"
     CDS             complement(20989..21720)
                     /locus_tag="JOX41_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HAY6449367.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(21889..22368)
                     /gene="greA"
                     /locus_tag="JOX41_001623"
     CDS             complement(21889..22368)
                     /gene="greA"
                     /locus_tag="JOX41_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HAY6449368.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(22504..23679)
                     /gene="mltG"
                     /locus_tag="JOX41_001624"
     CDS             complement(22504..23679)
                     /gene="mltG"
                     /locus_tag="JOX41_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HAY6449369.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            23883..25052
                     /locus_tag="JOX41_001625"
     CDS             23883..25052
                     /locus_tag="JOX41_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HAY6449370.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            complement(25319..>26105)
                     /locus_tag="JOX41_001626"
     CDS             complement(25319..>26105)
                     /locus_tag="JOX41_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449371.1"
                     /translation="GLTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFA
                     LQNTPLNIIQAPWRFMIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILN
                     YSSVVNMVKEMNFQGTYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVI
                     YSSFSPNKDEITFTFKSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSES
                     GINKVTIRYSYTFFSKISLFISIITLIVLLFYCIKLKIRTSHE"
BASE COUNT         7907 a         5199 c         4175 g         8824 t
ORIGIN      
        1 taaagaacac ttttgtctca cgctctaaac acgtataaac ggcgaaagca gaagcaactc
       61 cttcggaaat aagctgaaat tcacgaaaat tgcttttcaa atttttgtga attccagctt
      121 atttcttgga gttaaacgct tctgtctcag cctctttttc tttctagctt tttgattttt
      181 ctcttttctt ttgtactttt ctcttttcat tttcagttct acgcgtgtct ttatttttaa
      241 ctttttcctc tttatggatg attgatcgta ctttttgtgc aatttgctcg tttttgtccc
      301 agtcttttac atctaataat cgacataatc gtaacatctc ttcttttttc tgtttttttc
      361 tttcacgtct ttgccattct gtttccatgt gtcacactct cctttcttta atcatatgta
      421 cgcaaaataa tttttatatt tttttgatta gacatttcta tgattttaat atagtaaaaa
      481 gagccgtcac ggaaaatccg tcacggctct aaacaaaata tgagaggctg tttttgtttg
      541 gctattctta ttacttgatg cagggcagct tgtgtcaaga cttctttaca tcaaactttt
      601 taattttaca ttgggatatt tatccgcaaa ccagcgttct gcaaattggt tctcgaataa
      661 gaacaacggt tggtcgaaac ggtcacgagc caagatattg cgacttgaac tcatcttctc
      721 atccaaatct tctggatcga tccagcgagc gattttgtgt cccattggag acatgattac
      781 ttcggcgtta tactcattta acatacgata ttggaatact tcgaattgta gctgaccaac
      841 agctccaatg atatattctt ccgttagata tgttttataa agctgaatcg ctccttcttg
      901 aactaattga tagattcctt tgtggaagga tttttgtttc atgacatttt ttgcagtcac
      961 tttcataaac agctctggag taaatgaagg gagttcttca taagcaactt ttagttttcc
     1021 ttcgaacaat gtatccccaa tctgataatt gcctgtatca tatacaccga tgatatcgcc
     1081 tgctactgct ttttcgacgt tttctctcga atctgccata aattgtgtga cattgcttaa
     1141 tttcagtttt ttatttgtac gttccaacca gacatccatt cctcgttcga atgttccaga
     1201 acagattcgg acaaaagcga ttcggtcacg atgggctgga ttcatatttg cttggatctt
     1261 gaatacgaaa cctgaaaatt cttcctcata aggacttacc atctgatcat cttgtgtttt
     1321 gtgtccataa ggagctggtg ccaattcaac gaaagtctct aaaaaagtct gtacaccgaa
     1381 gttagtcaat gcagaaccaa aaaatactgg tgtctgatcg ccacgagcaa ttttttcttg
     1441 attaaatgca tctccagcct ctttgattag ttctacttct tctaagactt gttcatataa
     1501 ggaattttca gttagaggat gattttcggg aagcagtcca tcttcatcca attctactaa
     1561 tcgttcatcc tgataatttt ccggacgata aaactctaca cgattatggt agatatcata
     1621 aagaccttct agccctttac ccataccgat tggccaattc atcggataag attcgatatc
     1681 taatagctct tctaattctt ctaacaattc caatggttca cgaccatcac gatctagttt
     1741 gttgataaaa gtaaatatcg ggatgccacg tttttttaca acttggaata atttctttgt
     1801 ctgtgcttcg atcccttttg cactatcgat taccatgacc gcactatcca cggccatcaa
     1861 agtacgataa gtatcttcag aaaaatcttc atgtcctggt gtatccaaga tatttactcg
     1921 tttcccttga taatcaaact gcataacaga actagtaaca gaaatcccac gttgtttctc
     1981 gatttccatc cagtctgatt tggcaaaatt acctgttttt ttgcctttta cggtcccggc
     2041 ttgacggata gccccaccaa acaatagtaa ttgttctgta atcgttgttt tcccagcatc
     2101 cggatgggaa atgatcgcaa aagttctgcg attgtccact tgttgcttta attttggatt
     2161 attcataacc taactccatt tcttccattc aattatttat attttctcta ggcacagatt
     2221 gtccgatctc ttaaagaaag acaatttcat atagggctgt gacaaaagcc gtgtagcagt
     2281 ctctttttcc gagtaaacgg cgttctagag acagcctatc agcaataagc ccacccaagc
     2341 caaaaatacg aaaagctgtt tttgcttggc tgctcttatt acttaatgca ggatagcttt
     2401 ttcacaacct ttgtcaacta ctacaactga atcagtatag catggattca gcgaatgaaa
     2461 aagccaccaa accataagag tcaaatattt ttttgtcagc tgactaaaag aaaagacgtg
     2521 ttgcttgttt attcaagcaa cacgtctttc ataaccaagt ttccaattat cttcttggct
     2581 cgtcatcttc gaattctttt ctgaagtatc ttcgttcttc ttcaggttcc gcttctgttt
     2641 cttccggatc atgaaaaatg acacggattt taaggattcg agaaccttcc atttcttcag
     2701 aaaccagcgt aatattatcg acatcaaacg ataacttttc gccttcatcc ggaatcatgc
     2761 ctaatgctgt aatcaaataa ccagccatcg tatctacatc actcatatgc agatcactgt
     2821 caaaagcttc attgaactca tcaatcagca tacgtccttg gatgatatat tcgtgttcat
     2881 cgattttttc ataaagattc tcaacttcat ctgattcatc atcgatttct ccgacgattt
     2941 cttctaaaag gtcttctagt gttgctaacc caacgacgcc gccatattca tctaataaaa
     3001 tagccatctg attctgcgtc tttttcattt catataacag atcatcaata aagaccgttt
     3061 caggaacgaa taaaggctcc tgcatgattt tcttgatatc taaattatca aagccgaatt
     3121 tatgggcagc ttttagtaaa ttctttgtat gaaggattcc gactacttta tctttgtctt
     3181 cgttataaac agggattctt gaatagtttt cggataaaac ttcattcaca ttttcttcca
     3241 cagtgtcgtt gatatcaatc ataaatgcat ccgttcgtgg gaccatgact tctcgggcaa
     3301 ctttcgtatc aagagaaaaa accccttgga gcatttctaa ttcttcatta ttcaatacgc
     3361 cttcgttttc aagcatataa cgcatttcat ctctggtcat ttttgaatct tcatcatcaa
     3421 aagtcatcgg cgtgatacgc gccaataaac ttgtggaagc agaaagcagc cagacgaagg
     3481 gcttagctac tacaccaatc aagcgtatca gccctgaagt gaactttgcg acttcttctg
     3541 atttatttaa agcaatacgt ttagggtaca attctccaaa aacaatcgat acataggtca
     3601 aaatagccag cacaatgata tttgcaatat tttttgccgc tgtgccgcca cctaataccg
     3661 gagctaaccg ttccgataaa gtattagcta gtgaagcacc agacaaaatg ttgaccaaag
     3721 tgattcctac ttggattgtc gataggaaat tatttggatt ctgcaatatt tttaaaagct
     3781 tttgagattt cacatctcct tcatcagctt tttgctcgat tcgattctta ttgatcgaaa
     3841 caacagcaat ttcggaagct gctaaaaaag cattgatcaa tgtcaaaacg atcaataata
     3901 aaatctgcgc taacagcgac tgactctcag ggtcagcatt cataatcgca ttctctcctt
     3961 ataaaattaa tttttagttt acgatagaaa aaaacgtggc actatagcca cgttaaaatg
     4021 gtatcacaaa gcaattttct ttgcaataaa aacaagtgta ctaaaactac ctacgaggtc
     4081 gtagcaattt tcttcttgtt ttcattttgc ttgtcttctt tgacgatttt gattatatag
     4141 gaaatgatcg tcttgcagat tgcgtaaaaa ggaacaccta agaagatacc aagcaatccg
     4201 gcaatatttc cagctactag aagaacgata atgatcgtta atggatggat tttcagtgat
     4261 ttcccaatta cattaggata aatgatattc ccatccaact gttggacgat tagcacaacc
     4321 acacaacaaa gtaatgcttt taccggatca ttgaagactg ttactagaaa tgcaggtgct
     4381 agtcctagat aaggtcctaa atatggaatt aggtttgtca atcccgcaat gaccccaaat
     4441 aagaaagcat aatccacacc aattaccata tatcctaaaa atgtgaaggt accaacgaat
     4501 aaacattcga ttgcttgtcc gctaatgtaa ttagccaatg ttttattcag ttgccccaat
     4561 aactccacaa tttggtttct tcttttttct gggaaaaact gttggatgtt tggcactagt
     4621 ttttctccgt ctttcaacat atagaacaag atgaatggtg ctgtaatgat tactacggtt
     4681 gccgaagcga tcgttccaac gatcgaacct aaactattgg atactccact aaggaattgc
     4741 tgaatgattg tcccgtaaga aatgtctaat tgctcaaaat atttattgat atctacttcc
     4801 ttgaacaaag gcaattcggc tacctctttt aaccagcttt ctacctgttt gatgaaatca
     4861 ggcatattag atgccaatga ggaaatttgc tgtactagac ttgggatgac actaagtaaa
     4921 atccaaataa ttgctgcaac taaaaggagc agcacaattg cgacagccca tattcttttg
     4981 atttttgctt tcatcaacag cttgacaata ggattcaata aatagtaaag aaagcctgca
     5041 atcagtacag gtgcaaataa cgtggaaaaa aatgtcccga tcggttcgaa aataaagttt
     5101 atttctgatg aaatcatgat caatgcagct atgatcaata attcaagcga ccaaaacatt
     5161 agtttagact gtctaagttt ttcaaacaat agatttcctc ctttctttct tactagtata
     5221 tattatattc gttaaaaatt cttttattct ttttttattt ttgaaaactt gccatacttt
     5281 ttatttgttt tattttccag tatactatac gaaaggaagg tggctagacc atgaaagttg
     5341 tacaaacaaa agatacaatg agcaatattt acttagatgc tgtacggatc aggcatcaag
     5401 tttttgtagt cgaacagggt gtgcctttgt ctcgagaaat agacaaagat gaagcccatt
     5461 gtatccactt cgtcctgtac tcagataaaa aagaaccgca aggaactgta cgtcttttgc
     5521 ctttagaaaa cggaaaaatg aaattacagc ggatggcgat tctttctgaa tacagacacc
     5581 aagggttagg aaaaatattg attgaagaag cagaaaactt tgctaagaat caaggctata
     5641 atacgatttt attaggggca cagtccacag ctgaaacttt ttacgaaaaa ctaggatata
     5701 cagcttacgg cgatcctttt gaagatgctg gcatgcctca tatttatatg aaaaagactt
     5761 tataaaaatt tatttcgaaa aaagcaaaaa acagcaagct tttgagaaaa atctctcact
     5821 ggcttactgt tcttttttgt gtttacttac gcgacaattg cttgtaacgg ttataccaaa
     5881 tatcaatata gccttccgag aacgggccat ctccattatt gatccagtca accagaatct
     5941 tcacattttc ttttaggatg aagtcaatat cgttcgggta attcatcatt ttgctgtgca
     6001 tctcatattc atcgacatcc aatagtcgtt tctcgccgtc aggaaatacc ttgatatcca
     6061 agtcatagtc gatatatttc aaggcctcat cgtccagcaa aaaaggtgaa gctagattac
     6121 aataatagga aacccccttt tctctgatca ttgctattac attgaaccag tattttttat
     6181 gaaaataaac aatcgctggt tcgcgcgtta cccatcggcg tccatcagat tcagtgacta
     6241 atgtgtgatc attcacgccg atcatagagt gttcgcttgt ttttaatacc atggtatctc
     6301 gccacgttcg atgcaatttg ccgtcgtgct tgtaactttg gatcgtcaca aactctcctt
     6361 cttttggaac tcccatagca acccttcctt aagcagcatt ttgtgctttg tgtttgggtg
     6421 ttcattacac cgacatcata attattatat caataaaaat gagctttgcc tagaaaggat
     6481 tcctattgtt tcgatttttc tctaactgat ctaccagttt catttggacc ttaggaaaaa
     6541 cgaccgaatc aaatgcatca ggcttcaacc acttcgaagt tttgttctcg gtaaattctt
     6601 gttctgctcc ctcggttgcc cgtccgtaaa aaaggagaac atgccatttc agatgactaa
     6661 aaatatgagt aacttctcct aaatgtcgtg tctgccaaac aaagagttcc tgcttttcaa
     6721 atgggagatt ttgctcttct tctgctacta ggtcatcaaa cagatcgatt tctggctttg
     6781 tttcccattc ttttttcaat cgctcatact cctcttgtgt cacttccatc attggaaatg
     6841 tccacatatt cgccagcaat ttttggctat ctctttcttc aaaataatac gctccagaat
     6901 gattttgaag agctgcactg atataataaa cgtcttttgg ctttgctttt tttgttttta
     6961 caggaaaact cgtttggatt cctcgtttgt tagctaaaca aaaggcttgg atcggacaag
     7021 tctcacactt tggagaagtt ggtgtacaga tagctgaacc tagatccatc attgcttggt
     7081 tgaattcacc tggatgcttt tcatcaatga ttttccgcat cgcttcatca aagattttcc
     7141 tgctagaagc ttttgcgatg tctgcttcaa tgcaaaacaa tctgctgact actcgcatca
     7201 cgttgccgtc aactgcaggt tctggaagtc caaatgcgat acttgcaatc gcgcctgtcg
     7261 tatatggtcc tattcccttc aatgagctaa tttcttcagg cgtttgcggc atttccccat
     7321 caaattctga catgatctgt ttagcagcag cttggatgtt ccgggctctt gagtaataac
     7381 caaggccctc ccatgctttt aaaagctttt cttctggagc atttgctagc tcttcaattg
     7441 taggaaacca ttccatgaaa cgataaaaat aatcgatcac tgtgtctact ctggtttgct
     7501 gaagcatgat ctcagagatc cagatacgat aaggatcacg attatagcgc caaggcaggt
     7561 ttcttttttc ttgttcatac cattgaatga actgatcttg aaattctttt gtttctttat
     7621 ctgtccattt ttcccattct ttattcactt tcctcttcct tttccgtaat gaatcgctgg
     7681 atcatatcca aatcaaatcc tttttgatat aagctttgct ttacttttag atttcttttt
     7741 ttaggttcaa accttaaatt tcttcgccat agtttatctc cttgtttgac taaataatca
     7801 tattctattt cttgatctgc ttcttgcgga agatcagcta tcgcttgttg gatcacttct
     7861 tgagaaaagc ctttcgtcat caatgtttgt tggatttttc tcaataattc tttttggctt
     7921 tttccgtgat tttttccaaa cgctttttcg gctgtctgat gtgcattttg aacttggtct
     7981 tcaaatgtat attggctgag cgcttgttca atgatttcag gtttcaaacc tttttgctgc
     8041 atctgctgcg ctaatttctt tggtcctttg tcacttaagc gcatattcgt gcgcacataa
     8101 ctttccccat agaccaaatc atcgacaagg tccaattctt ttaagcgggc tacgatttta
     8161 tttcgatctt cttgaaggat ttccttttct tttaagtatg ttcggatttc tttttccgat
     8221 cgcaactgat aacttaagta attcattgct aggtgaaaac cgaaatcagc tccgctactc
     8281 ttcttgatct cttggatagt ttcttcgtct aattcccgtc cttttaataa tcgatagcgt
     8341 actaatacat cttcagatac ttgtaaagct tctccttcag ataaatctac gcgatagaaa
     8401 gggcctttgc ctttactgat tctcgtaacg gttaacataa acatcctcct cgaacatata
     8461 ttctctatca taccacagaa aatccccgta atcaggtatt atatgttaga ataaaccaca
     8521 gaaaaaagaa aaagggagat acttatggca gaaacaattg tcaaaactgg acaaacggtt
     8581 cctttgaaaa tcaagcgttt aggcataaat ggtgaaggaa tcggttattt caaacggttg
     8641 atcatatttg ttccatatgc actaccaaaa gaagaagtac tagtgaaaat cacgaaagca
     8701 actcctcgct atgcagaagg agaattaata aaagtcaaaa aaacaagcaa agatcgcgta
     8761 gtggcaccat gtcctgttta ctatgaatgc ggtggctgtc aattacaaca cttagcttat
     8821 caagctcaat tggattttaa aaaggatctg cttttgcaag cattggaaaa attcaaacca
     8881 gcaggctttc gatcttatca acttttgccg acgatcggga tggatgagcc ttggcattat
     8941 agaaacaaag cacaatttca gttacgaaaa aataagcaga ctcaaaaaat tgaagctggt
     9001 ttatacgaag caaactctca tcagttagtc cctataacag actgcttggt tcaagaacct
     9061 cgaacacaaa aagtaatgaa tactgttgtt caactattga ataaatttga tgcacccatc
     9121 tatgatgaac ggacaaacag tggaatcttc cgcacaatca tggttagaat cggtgttaaa
     9181 actggggagt tacaagttgt ttttattact cgcagtaaaa aattcccgca aaaaaacgca
     9241 atgatccgtg agatcaatga acgactgccc gaagttgttt caatcatgca aaatgtccag
     9301 gcacaaaaaa cgtctctcgt gatgggggat gaaacgatcc acttatgggg aaaagaagcc
     9361 attgaagaac aaatcaatga agtgactttc gatctttctc ctcgtgcctt ctttcaactc
     9421 aatcctcagc agaccgaatt gctttatggc gaaggaatca aagcattaga tgtccagcct
     9481 aatgaaacga tcgtggatgc ttattgcgga gttgggacga tcggcttaag tgtagcaaaa
     9541 caagccaaag aagtacgggg aatggatacc gttcctcaag caatcgctga tgcaaaaaaa
     9601 aatgcggaaa gattaggata tcacaacact cgatatgaag tcgggacagc agagcaagtt
     9661 ctgcctaaat ggttgaatga aggttttcag cctgatggta tcatcgtaga tccaccacgt
     9721 acgggtttgg ataacgcatt gatccaatca ttattgaaat accctccaaa aaaacttgtt
     9781 tatatctcct gtaatgtttc tacacttgcc agagatctgg ttaatttaag taaaaagttc
     9841 aagattgaat atttacagtc cgtcgacatg tttcctcaga ctgcacgttg tgaagttgtc
     9901 gtgaagatga cgagactcgc tgactaaatg aaagaggttg tgaaaaagtc tgccctgtat
     9961 caagtaataa gaacagccaa acaaaaatag ctcttcatgt tttatgaata ctgtacttgt
    10021 gaccgaagag ttaacaggag gacactattt atttaaaaaa agggttgtga catagttttt
    10081 gtcacagccc tttttgatta ttattggata ttcacgtcta tcacttgata aaatgcattt
    10141 gtcgtatcgc tgatattcca tactgctaaa atcacattat atccttttcg atcctgcgga
    10201 agtgtgatcg tttggttgac tgtttttggt ggaacagttg ctttgtcgtc tatttttgtg
    10261 atcaattcaa aatcactaaa tttcaaaggt tgattaggat tccaagttgg tttggtaatg
    10321 tagtaatccc aagtacttgt ccgatgttgt gctgttaaat tccaagtaat atttaatgtt
    10381 cctggattaa ccatgttttt atgccatctg ttagatgtct gttcatctaa aggctcaaag
    10441 ccgctgactc ctgcactagc aatttttcca tcaatgaatg tatttttggt agcttcgata
    10501 ctttgcggtt cccattgtgc tcttccgaca ttttgattta agtttcctgc tgctgatgtt
    10561 cctaggtatg cacggcttcc tggagaagta atataaccat gcgcaaaacc tggaatgcta
    10621 aaaccgaaca accctaaact aactaaccca ataaacaata acgtactaat ctttttcatg
    10681 tagaaacctc cttcatttga taaccacatt gtaaacgctt tattgtatta acacaaacat
    10741 tatgctttta taattttatg ttgaagtaaa aaaggtgaaa aaagtaagat gcagattata
    10801 acagaagtag acgagaaaag tacaaataga aaacatgaga atcaaatcat atgatctttt
    10861 tcaaaaacat cattcatata aacaaatgtt caacttttta ataacaacaa ttatcaattt
    10921 ttttcttact tcacaaacta aatacaggtc ttgctgtgag ccttcatggt aaactaatat
    10981 tatagaaagg agttagtaaa atgaagatga taaaagatat tcgtttttgg gtttgtgtta
    11041 taggaattgt catattaggc tttttatcag ggttgcttag cggaaatccc ggaaaatatt
    11101 actattcttt gcaacttcca ccatttgcac cacctagctg gatatttggg ccgatgtgga
    11161 ccttactgta tatattgatg ggtatttctc tttatttgtt acttaatcac aacaacaaaa
    11221 aacagcgaaa caatcttgtc ggtctttttg tgattcagtt catttttaat tttatatggt
    11281 ctgctctatt ttttaattta agaaatattt tcattgcagc aatcgatatt acacttttag
    11341 ttattttctt gtcagtgctt atgtatcagt tgtggctgca tcatcgcctg gcaatgtggc
    11401 tcatgattcc ttattattta tgggtactat tcgcaactct attgaattat tcaatttatt
    11461 ttttaaacta agcgctaaaa agagacgtcc tgtaatttaa cacatagaaa aagtgccacc
    11521 taagttagat tttttgtcta atttaggtgg cactctttat taaccaaact atttttttct
    11581 agtacccact tgttgttcca tactcattat tctggtcata accataacca ttttgttcct
    11641 gtccagcgta aggatcataa ctttgagtat cttgacttgg tgtatagtac tgacttgtat
    11701 cttctgtttg ctgataatag gtattcggat cttggtactg atcatatgtg ttttctgaat
    11761 aggaagaata atcggtgtac ccttcactat tcgatccatc accgtttgtc gaatcgccat
    11821 cttccgaatc atcaaagaac atcattgaag cattctcatt tttcaaatta ggtaatgtat
    11881 cgcttgtttt tatatttaat tgtttcttca gttcattttg gatcgaaaga agatcatttt
    11941 ttcctaaaat ttgatagtag atatcattga tcatttgtcc ttcgccttgc aactggtctt
    12001 gtttgattgt ttcaaacgcc ggggtgtagt tcgtcgctac atcaagcatg tcatcccaat
    12061 ctaagtccgt cgtcacattg ttctcaactg cttttaaaat ttttctataa ttgcttacgc
    12121 catctaaact taaaacttta ttgacgattt tcgtcactac ttcccgctga cgacgttgtc
    12181 gaccgatatc gccttctgga tcttcgtgtc gcattcgaga ataggctaaa cctttttctc
    12241 cattcaatgt ttgttcacct actggtacat ggacaccatc caaagtaaag tcaattttat
    12301 tattcacttt gatgccaccg accgcattga tcaaatcttc catgccatcc aaattgatcg
    12361 ttacataatg atcaatagga atatcgagca gttgctcaat tgaatccatg gccatttcga
    12421 caccaccaaa tgcgtaggca tgatttaatt tatctaccgt tccataacct acgatattcg
    12481 tataaatatc tcggtccaaa ctgatgatcg ttgatttttt ttgtttcgga ttaactgtta
    12541 ctaccatcat cgtatcagaa cgtccttgtt ccgttcttcc taatccaccg gtatctaaac
    12601 ctaatagcaa aaccgaaaaa ggttctttgt catcaatgct tactctctca gaacgtttgg
    12661 aggatattcg attagagttt ttagaaattt tgtttactgt ttggctcgct tctcccataa
    12721 atctgattcc gtatgctgat aatccggcaa tcagcaaaac gaatacccct aacaaggtta
    12781 atagaacttt ttgccatcgc ttcataatac acctctgttt cacattttct aaaatattgt
    12841 ctcatataac tgttcaatca gcaaattcac tttttaatca taagaaaact ttaaaaaaca
    12901 tttttgtgta acgattatta ttttttaaaa tttctcaaaa ttcttaacta tcataccata
    12961 ccgtgaaaaa gatcgaaaga ccgaatacac gcagttcgca atcgttttat ctttttttat
    13021 gtattttttc cagaaaaagc gaacaacaag gtattttcca aataatcgtg cagtaaaatg
    13081 atcgcacata cctttcccat ctttttaaca gtctttgcct accgttcaga ttatcattcg
    13141 atttcacgac aatttcttcc tatgactggt ccttttgtta aacccatctt ctattcgttt
    13201 tatttccagc tcactgcatg gctcttaaaa tgactcgaac tagtgattgc attaccatca
    13261 tcttttaatg gatagatatg ctcctcttca aagtaaaacg attttctttt aaagtaatag
    13321 aattgacatg gtaatgagta tgtatactag tggtttcaca aatggtcttt tattcaacat
    13381 ccaaaaactg aaatttcttt aaaatccatt actaacgaag aaaatgttcc ttgcttgata
    13441 attagttagg acatgtcaag tgaacaaatg catttactta gccaaaaaat ctaaaaactt
    13501 cataaataga caaaaagaca cgactctcta agaagtcgtg tctttattca acaaattatt
    13561 ataatttagt cacttcagca gcttgaggtc cgcgtgcacc ttcaacaatc gtgaattcta
    13621 cttcttgacc ttcttctagg ctcttgaagc cgtctccttg aattgctgag aaatgaacaa
    13681 atacgtcatc tccgccgtct actgtaataa acccaaatcc tttttcattg ttgaaccatt
    13741 taaccgttcc gtgttccata aatgtatatc ctccaaaaaa gttcttgcaa gtaaccttgc
    13801 aagaacatta tacccaattt agaaaacgct agcaagcttt cgctctttta ttttccaaat
    13861 tatttttaag actgatatga cggaggaaat ggttattttg ctgcttcgaa acgtttgttt
    13921 acttcatccc aattaataac attccagaat gctgcaatat aatctggtcg gacattttta
    13981 tatttcaaat aataagcatg ttcccaaacg tccaaaccta gaattggtgt ctttccttcc
    14041 atcaatggag aatcttgatt tgcagtagag gtaatagcta attttccatt ttccattaca
    14101 agccaagccc atccagaacc aaatcgtcca gcggctgctt ttttgaattc ttctttaaaa
    14161 gaagaaaaat caccaaaagc ttcattaatc gcttctttta tttctcctgt aggttcgcca
    14221 ccagcatttg gtgccatgat ttcccagaaa aatgaatggt tagcatgtcc gccaccattg
    14281 ttacgtacag ctgtcttgat atctgttgga atagcgtcca tatcagataa taattcttct
    14341 attgtttttt cgcctaattc tgggtatttc tcaattgctg aatttaaatt cgtcacataa
    14401 gtattgtgat gcttatcatg atgcagatgc atcgtttctt cgtcaatata aggttccaat
    14461 gcgtcatatg cataaggtag atctggtaat gtgtaagtca taaaaaaatt cctcctcaat
    14521 gttttcttaa taatgtctac attacaaaga gtaacaaaga gaaggaaatt cttcaattgt
    14581 tatgcctagt cgtctttttc actttgacct acttcttctt caaaaacctc agtttcttta
    14641 aaaataaaca acttgctgaa aatatagttc gcaaggataa caataatttg agtgatgatt
    14701 ttcgccacat actcattgct gttcataaca ttgatcaaca ataccattgc ccccatgtcc
    14761 aatccgtaag aaaggatacg gtagaagaag aacttaccgc attcaataag tgcatgtgta
    14821 aaattcggtg attttgaatg gaatacccaa agtttgttcg ttacaaaagc aaacaataca
    14881 gaacaaaacc acgaaataga attggataag gccatactta aatcaaaata ttggcgtgcg
    14941 agagcaaaac taacaaaatt tacaatcgta gccaaaccac caaaaaagag atagactagt
    15001 atctcccaat atccttttgc ttctaaatat ccttttaact gtcgatactg cttcatgagc
    15061 caacctacct tattaaaaat tcttatttat catactctat atttcaataa ctttcatctt
    15121 tatttaaaaa aattaatttt ttttgatcct ttgcctttgt ctctgcttgg atcgtcacat
    15181 gtgtaatacc atattttaat tttaataaag aaattatacg aggatatatc ttttcaatct
    15241 cgcttagtag ctgatcttca aaatcaatat gtccgtcgaa aataattatc ttttcgctat
    15301 actgccaaat atggacatga tgaacatcct ttaccccatc gattgcttca atttcttgtt
    15361 ccattttttc atagtcgata gcaggtgcac tttgtatcaa aatagcggca gcttttttga
    15421 tcaccattat cgcttctatc aatatatata tcgaaatgat cagtgtaata actggatcga
    15481 tccagtagat atcgaaaaaa cggatcaaaa ttgctccgat aatcacactt accgaagaca
    15541 gtgtatcact taacaaatgc aaataactag attttatatt caaactttca tctgcttctt
    15601 gtcgtaataa taatactgag aacaaattcg cgagcaatcc aataactgct actgttagca
    15661 tcaaatgact atttatcttt tctggtgaag tgaaccgctt gaatgcttca acggttaaaa
    15721 acaaggataa tatgatcaat atgaatgagt tgatgaaagc actcaatatt tctaaacgct
    15781 ggtagccata cgtacgtttt ttatttgctt cttttcgggc cattttttgt gccccgtaag
    15841 aaaaaataat tgccaatgta tcactaaggt tatggaaagc atctgaaaca agagacaaac
    15901 tccctgacat aatccctcca ataaattctg ataaagtgat caccgcattc aaaaccacta
    15961 ctccaaatag tttttttgat gatctctgtg gctgtgtagg cactattcct tcctccattt
    16021 tatttatatt ggatagtctt tagacaagaa taacattttt ttgatatttc accaatcatt
    16081 cagctgtttc cttaaagcac ttgtatttca cttgatactt cgctagaatt gcaagtgatg
    16141 acactactag atgaggagta cttatgacaa caaaacaatt aattatcagt tcctttatac
    16201 gattcaaaga cctaaaggag gcgagaaatg tcccattttg gaaagccatt gtctatcttt
    16261 tagttttgag tataattatg gctttgccaa tctcttttca agtttttcaa gtcttaaaca
    16321 acattcaatt ggatgggcaa aagattgcta ctcgcattcc tgattttaca atccaaaacg
    16381 ggcagcttca aaccgaagaa aaagaaggat tcatttacca aacaaactcc attatcttca
    16441 catttgatcc agagggaaaa cgaacagaac aggacatctc tactgatttg atggggaatt
    16501 ttgttagtgt cgggatgtta aaaaacaaac ttatcatagc tcttcctaat acaggcacga
    16561 cttctgcttt gttgaacaat aaccaattag aacttcccta caccaatgaa tctttaaaaa
    16621 acttaacagg taagcagctc cgttcttttt taagtgaagc atctatacca ctttggataa
    16681 aagtcctgac atttatattt tctatttatc ctagttttct gaatctgctg atcactttgc
    16741 tatttaccaa cattgctgct tttctctatg cacgctttcg actaacaaaa gctacttttc
    16801 ttgattgttt aaaaacattg atctattcaa tttcattgcc tactataatt gcaacaatct
    16861 tgatggtctt tcttccttct tttgacacta gcgccttcat tgcttttgca ggaatcttta
    16921 tttttgctca agctgtcaaa ggatgggcaa aaatatcgat caattaagaa ataaagacaa
    16981 ctcgttattt ctacttcaat agaccctttt agaggttgtg acattttttt gtcacagccc
    17041 cttttttatt tgaaaaatat ttctttctca aaaaacaagc aaggcgcttc aaagttcttc
    17101 ttgtatgcgc tacacttaga gtaaagaaag gcgggaaatt aactatgtca gaaagaatca
    17161 tttatgcaga tcgtccattt cgtgatgaat ttatcgaaga aatccatact atagcgcctg
    17221 gttatatctt taaaacagaa ttacaaccag aggatctaca aaatgtagag atcagtttgg
    17281 gctggaactc agactaccaa gaaaaactat tagcctcttc taccttgaaa tgggtccaat
    17341 ctatctcagc tggtgttgat cagctacccc ttgagacttt ttcaaagaaa catattttac
    17401 tttcaaatgg tagtggcatc cacagtgaat cgattacgga gcatgtctta ggaatcatcc
    17461 ttgggtattc tcgtggtctt tttcaagcac aaaaggcaca gagtgacatg aaatggttag
    17521 gttcatcggt ccattaccaa tctatccaag ggaaaaaaat actaatcatt ggaactggcc
    17581 atattggaaa aatgattgca aaaaaatgca aagcattaga catgaactgc tatggaatca
    17641 atacatccgg tcatccagca gaaggaatgg aaaagacttt ttctttaaat caactaaagg
    17701 aagttcttcc tgaagtagat ttcgtagtca atatcttacc tctaacggag gaaacaactg
    17761 ggctctttga tcagcatatg tttgaacact ttgatccaaa atctgtattc atcaatgttg
    17821 gccgtggtgc ttctgttaag acacaagatc tggtgcaggc tttaaataac cagcaacttt
    17881 cctttgcagc attagacgtt tttgaggaag agcctcttcc acaagatcat cctctttgga
    17941 aaatggacaa tgtactgatt acttcccaca ttgcaggttt gacacctgat tttcaaaaga
    18001 aattaatggc tattttttta accaatctga aaagctactt tgccacccat gagcttcaaa
    18061 ccaatcaagt aaaattgtct gcaggatatt aatagctgaa aacaatattt tcaaaagaaa
    18121 aaagagaagg tgacaaaaat tgtgtcaccc tctctttttt tattgttttt taaagtgata
    18181 ggttggctcc tccaggttgg gatcataatc aacaagtaaa tcatatcctt taaagaacca
    18241 ttcatctgct tcctcgataa aaaaaagtgt cccatcaatt tccactttct ttacaggatg
    18301 ttctggctgt tcaactgaca ttccaatcga aaaaccatca tgaacctctg ttttgccgta
    18361 gacttttcca aaaaaacgta ttccgtaagt ttctggcaga tcaatttctg agtcaaacca
    18421 cttttgtgct tttggcgtta ccgttaattt catcccaaca acctactttc tcttttcttt
    18481 ctattgattc atcttatcgt ctagaatatc cacatcgcct gtctctccaa taaccagtag
    18541 attatcattt tcacgaacat attcatctgc tgcaggagaa gcgataaccg tttgatctac
    18601 tcttcgtatg gcgactactg ttaagtcaaa acgttgcctg aaatttaatt cagctaatgt
    18661 tttgttgaaa aatttaggat tggagactcg gatttctgct aaagaatatt tatctgacaa
    18721 ctctaggtaa tctaaaatat tctttgacac taaattatgc gcaatcctta ttcccatgtc
    18781 tcgctcggga tggacgacgc gatcagctcc gatcttttca agtactctgg catgatactc
    18841 attttgggct tttgctaaaa tatttggtac gcccatttcc tttaccatca gagtaactaa
    18901 gatactggct tgaatatctt ctccaatagc gacaattaca tgatcgaaat ttcttatgcc
    18961 taatgatcga agtgtcattt catcctgtgc atttgccaca acagcatgag tggctatatt
    19021 catatattca ttgacccgat cttcattact atcaatagcc agtacttctt gaccagcttc
    19081 gatcagtgtt cggcagatac ttccgccaaa tcgtccaaga cctacaattg caaaattttg
    19141 tttcaccgtt ttcctccttt agtatcttct tttctcagta taacaaagcc tttacaaaaa
    19201 caaaagcaag catcattatt gtaaaaaagc caagaaaaat aatagttatt ttctcagctt
    19261 ttgattatcc tctttatcat cgtttttatt tcaccaaacc atgtttgaat gcatagatag
    19321 cggcttgtgt acggtcttcc acttctagct tagccaatat attggaaaca tgtgttttta
    19381 ctgttttcag tgtaataaac aattcgtccg ctatttcctg attacttttt ccttcagaaa
    19441 tcagcattaa aatttcattt tcccgattcg ttagttcttc atgtaataca ggctcatttc
    19501 gccgactcat tttttccatc atttttgttg tcacttctgg ttctaatact cgctcgccac
    19561 gttgcgttgc ccttatagca tcagcaattt catgtgcggt agaggtcttc aacaaatacc
    19621 ctgctgcacc tgcttcaatg gcaggataaa ctttttcgtc atcaataaaa ctggttacga
    19681 taatgatttt agcttctggc caatctttta agattgcttt tgttgattcg ataccatcca
    19741 tttcttccat gactaagtcc attaaaatga cgtccggtcg aagtgtcatc gccttctcat
    19801 agccttgtcg tccattttca gcttctccaa ttacttcaat gtcttcttga atagataaat
    19861 aaaaagagac gcctaagcgc accatttcat ggtcatctac taataaaact tttatcatcc
    19921 ttatctatgc ctccttcatc aaagggacct tgatttctac acttgtacct tgacctttaa
    19981 aactaatgat ttttactgtt ccaccaatac cagctactcg ttctttgata ttgttcaatc
    20041 cataacttcc cgttttcgtt tcattcatat taaaccctgt tccgtcgtca ataatacgta
    20101 acaaaagatt attgtctatt ttgtgcaaat atacctctaa ttcattggct ttagcatgtc
    20161 ttaatgtatt tgataacaat tcttgaacga ttcggaacaa gtgatcctca atggaactag
    20221 atagttttac atcttctaca tcccatttca gcgaaatctg gattttattt tgcaattcct
    20281 tcaataactg ctcgatacct tgctttaaac ttttctcttc taaattgact ggacgtagat
    20341 gaagaagcag cgcacgcatc tcagactggg aagcgttgat gatctctgct accattttca
    20401 actgcttgcg aaacatttct ggtgtctcgc ttttttctgc ttgctccgtc aatgccgaca
    20461 tcatcatcat tgctgcaaac aattgttgcg aaactgaatc atgcagctca cgggctaatc
    20521 gatgtctttc taattctaaa atttcttctt tggtttgtcc atctacatat tggggacggc
    20581 tcgttacaat ttgtaattca ctagatactt caatcatttt ttcttttatc ttagtgattt
    20641 ccttatcaat atctttgatg tataaatcgt ccgatgcact tgggatcgga agaagcaaca
    20701 atttggattc ataattgcca gaagaaagtg cacgcagctt ttcttcgatt ttcccgtatt
    20761 ttgtcttttg aataagtgat aataatagaa agacaattaa tcctacacct aaggaaatgg
    20821 ctaacaaatg gaagataagc ggaacatata ataaacgtgc acgcagtaat tctccccacc
    20881 aatgactttg attgctggca taaaaataag tgaaaagtga aaatagaata ataaggaaag
    20941 ccgcaatccc cgaataaaca gctagcatcg ctctggatat ttttcccatc atattcgtat
    21001 cacctcgaca tctccaatca aggtattagt aataatcttc aatctacgag ggttttcatc
    21061 ataatcactg ctgtagattt tgatttgttc atttttcaaa gaaaattgct cttcttcaaa
    21121 caagacattt cctactaatg tcgcatgctc taatcggatg gctacgccca aaggtactaa
    21181 gatccgtgtt ctgcctatcc cttttcttac aatcacaata ttatcatctt ttggcaaaag
    21241 cgtattgccc aaatctatga tagtatcacc agaaatgacg gcgatgttga tatcgtccca
    21301 ttcatagacg tcgtttccaa tacgttggtt accgaataat tgctgtcttt tccgctcatt
    21361 attatgtgtt tttaattgct ctgtttggat catcatgatc tgtttctttc gccaaaaagc
    21421 atttttggtt aaatctatcc ctgaaatctc tacacctttc agaccaataa ataaaacggc
    21481 aaatacagcc atcatccata aagcaggact gttgactaag ctaaaaaaaa tgaccaaact
    21541 tcctaatatc aattgaaaat tttgaaattt agtacgagga tgtttgcgca tagctagata
    21601 tatattgaaa ataccgaata tcactaaaag caaaagtcca gtattgttta cgatttgcca
    21661 aacagcaaat aacagcagta gtgcttcaac taccacaaaa aaacgccaag aactattcat
    21721 cgctctttct ccctcctgac acattctcat ttcatcatac ctattttttt aactgttggc
    21781 tataggactt tagatgtaag atcgtttgtt gaaatctaaa atacacaaag agaaaaagat
    21841 ctagagtgta tcatcagtaa gatgaactct ctagatcttt cagtcagact acgcttgttc
    21901 tactttgacg attttaacta acatatcgcc acctggagta gcaatagtta cttcatcatt
    21961 tttacgtttg ccaatcaatg cttgcgcaat aggagaatca ttggaaattt tgccagaaaa
    22021 cggatctgct tcagcgcttc cgacaatcgt gtactcttct tcttctccat ctggtagttc
    22081 gatgaatgta actgttttac caattgatac ctcatctgca tctacaccgt cgttatcgat
    22141 gatttgagca aaacgaatca tattttcaat tgttgtgatt cttccttcaa caaatgcttg
    22201 ttcatctttc gctgattcat attcagagtt ttcggaaaga tctccgaaac cgcgggcaat
    22261 tttgattcgt tcaatgattt ctccgcgttt gactgttttt agttcttcta attctttttc
    22321 taatttttct ttaccttcta gagtcattgg ataaactttc tctaccatgt gtaacgtctc
    22381 cttttttcga taaaataccg caaaaggtaa tcttttgagg aatatagtcc aaaaaagatt
    22441 accacgcttt tcttcaaatg taaatgtttt tctaaaaatg atcaatgtct agagcctgtt
    22501 tttctaagaa ttatttacat atttttccac taattccata tgttcttcat aagttttagc
    22561 gaaataaaca tttccagtgc tcgtatctgc tacgaaataa taatagtcat tttctgctgg
    22621 ttctaatact gccttgattg cctcttcgct tggattgtca aaaggtccag gtccatagcc
    22681 ggtattggta tacaaattat atggtgaatc tacagctgta tcttcatacg tcactaattc
    22741 tttgtgttca cctaatgcgt ataaaacaga gatatctgac tgaagtggca tatttgcttt
    22801 gattcggtta aagaagactt gtgcaatgtt tttacgatca ttttctttta cgccttcttt
    22861 ttcaactaga gaagctagag ttaaaacttc ttgtacagtc aaatttttct gcttgatagc
    22921 tgaataatag ttttgcatga ccgtattcgt cttgttcacc atttcaatca ctagatcctt
    22981 aagcgaagta ctcgtgtaat aatcatatgt ggctgggaat aagtaacctt ccaaacggta
    23041 ttttgtgttc tcagctttag atgcactttc caacagttct gggaattttt ggtgcaactc
    23101 gttaaagaaa gtctcatcat tcactaaatc taaaaattct ttcttgtctt taccagttac
    23161 cttcgctacc cgttcagcaa tctgatcgat atcgtaccct tctggaatgg caattttccc
    23221 atctgcaact tttgttggct cagaagtacc gccttcttgc aactgtttgc caatctcgtc
    23281 aagagtcata ttaggcgcta actgataata gccagcttga aagccagtta aatttttaaa
    23341 ttttgtataa taattgaaaa caatcccgct tttaataata ttgtccttct ccaaaatctc
    23401 accaatctgc ttgttagaag agccactcgg gatctcgact tggactaatt ggtcatctga
    23461 tttatctaaa ggcttcaacc cgctatctac ataacgatac acggtaaatc caagaaatcc
    23521 gccaataatc aataatgtaa gagcaatcac taaaatgatc ttcctcacaa tcttatcttc
    23581 ttttttacgc agatttctcc gcttgtcgat tatatctgct gtagctgcct tactggcttc
    23641 ttttttatct ttacttgggt gttgtttgtt tcctgacaaa acaactcctc cttactatca
    23701 agttcgtaac tttattcatt atacatgata tttgaattgg cgtgaatgat tttatttaaa
    23761 tattctatca aaaatgtaag tagtaaatcc attactataa gattaaaata aatgttatca
    23821 agatacaagc tattttagct ttattctttc tgtaaaaaag aaaggagact aaataaacta
    23881 ttatgaaaaa aggaaaacat gctaaaaaaa gaaaatattc atttttaatg atcgttgtcg
    23941 tgttgtttag ccttagtgcg ttctctacag gaactattct tggatggcaa ttttacaata
    24001 atgaacactc tcagatagtt gcccatgctc aatcagctca aaaaaagttg atactgacta
    24061 ccaatgaaca acagctcgtt gaaaaaatcg atcaactatt aagaaaaaat gattatattg
    24121 gctcaattta cgtaaagaaa aataatcgca tcatcatgga aaaaggctat ggctatgcga
    24181 ataaactcac gcaacaacca aatgatcctt ctctttatta tcagattggt tcggttcaaa
    24241 aagcattgac tactcttttg attttaaaac aagtcgagcg tgggcacctt tctttagata
    24301 ctaagctggc tcaattctat ccacaaattg ctggcagcca gcaaattact atccgtgact
    24361 tgctgtatat gcgctcaggc ttgcaccgaa ctgcttctcc aaccataccg atgactgatg
    24421 aagaagtcgt tcaatttgcg attcagcact taaaatttac agattatcag acctctcatt
    24481 atgattcatt gaactttacc atattgactg gaattttgat caaattaaca aatcaaccgt
    24541 atgaaaaatt attgaccgat gatatcatcg aacctttagg attacagcat acaaaatttt
    24601 atgaccaagt caaaaattca tccaatcatg cactatccta tcaaatgtct aaagaggatg
    24661 attactttaa accactgaca gaatctgaaa cagagatcca taacgaatta gggactggta
    24721 atatcagtat gtccgtctat gatttaaata cgctgtttac acaagtttta tctggaaaac
    24781 tagtttccaa agacttactc ttctcattat ggcgtgaaaa tgcgaatgga catccatata
    24841 gtggtggggt atatagcgga gataattata tcctgtcgca aggaaatatc gactcttttg
    24901 atacatctgc tatatttagc aaagattcac aggatgctat catcatggaa agcaatataa
    24961 aagctgacaa aactatcaaa ctgcctactg ctgatctaag aaaccaaatc tatgacctga
    25021 tggaaggaac tactaagttg gcaaatagct gatatgatga aaagatagca aatactactt
    25081 ctttgaatag catttgctta aaaaaagtac tcgactaaac gtaggaaaga gtgtgggaca
    25141 aatctaaaaa tcaatttttg ctacagactt taattccaaa taaacagaac agaaagaggt
    25201 gttcttcttt ctgttctgtc caaattattc taagatttct ctttaccaac attatttgac
    25261 aaagggccta ttaaatctaa aatagtatct ttagattgct aaaatatgtg ctagcaaatc
    25321 attcatggct tgttcttatt tttaatttta tgcaataaaa aagaagaaca attagcgtga
    25381 ttatagaaat aaataatgag attttagaaa aaaatgtgta tgaatacctg attgttactt
    25441 tatttattcc actttcactt tttactgtaa caaaaggacc tccttgtttt agtactgtag
    25501 cattttttga attaacagta accgttaatc ctttataccg gaatacaggt aaaactattg
    25561 ttttgccttt tgaagattta aacgtaaatg taatttcatc tttatttgga gaaaagctac
    25621 tataaataac ttgaccatct tctgtaactt gatggttttt caaaagcaat tgatcttttt
    25681 tatagcctat aggtacataa tcaaaattct caaattcttc aagtttattt tccatttgtt
    25741 cattagaata agttccttga aaattcattt ctttcaccat gttaactact gatgaataat
    25801 ttaaaattga aatagctaat attaataata gtataaaatt tcttctcctt gtataagaaa
    25861 atttttccaa ctgtggagaa ataaatagag atactgaaaa agatatgaac aatgttgaaa
    25921 atatcataaa acgccaagga gcttgaataa tatttaaagg agtattttgt aaggcaaacc
    25981 atggaaatat ttttgtacaa agtagaatag atattatacc cattatataa gtgattttag
    26041 ataagattcc taatttttta aagttaaatg ttagtataat taaacaaata agcaaagtta
    26101 agcca
//
LOCUS       DADLIO010000036        25358 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.036, whole genome shotgun sequence.
ACCESSION   DADLIO010000036 DADLIO010000000
VERSION     DADLIO010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25358
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.036"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(132..509)
                     /locus_tag="JOX41_001627"
     CDS             complement(132..509)
                     /locus_tag="JOX41_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449372.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            765..1493
                     /locus_tag="JOX41_001628"
     CDS             765..1493
                     /locus_tag="JOX41_001628"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HAY6449373.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            1493..1747
                     /gene="purS"
                     /locus_tag="JOX41_001629"
     CDS             1493..1747
                     /gene="purS"
                     /locus_tag="JOX41_001629"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HAY6449374.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            1749..2420
                     /gene="purQ"
                     /locus_tag="JOX41_001630"
     CDS             1749..2420
                     /gene="purQ"
                     /locus_tag="JOX41_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HAY6449375.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            2421..4643
                     /gene="purL"
                     /locus_tag="JOX41_001631"
     CDS             2421..4643
                     /gene="purL"
                     /locus_tag="JOX41_001631"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HAY6449376.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            4628..6067
                     /locus_tag="JOX41_001632"
     CDS             4628..6067
                     /locus_tag="JOX41_001632"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010768528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HAY6449377.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            6099..7142
                     /locus_tag="JOX41_001633"
     CDS             6099..7142
                     /locus_tag="JOX41_001633"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HAY6449378.1"
                     /translation="MANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGFGGC
                     FDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEPLYF
                     LDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFAVGI
                     AEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKKTLG
                     EELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSWPIL
                     PIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVQESKVKEIVHEIEQAGEKVYEIGKVIA
                     KEKHRVVFIGEER"
     gene            7139..7717
                     /gene="purN"
                     /locus_tag="JOX41_001634"
     CDS             7139..7717
                     /gene="purN"
                     /locus_tag="JOX41_001634"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HAY6449379.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            7714..9249
                     /gene="purH"
                     /locus_tag="JOX41_001635"
     CDS             7714..9249
                     /gene="purH"
                     /locus_tag="JOX41_001635"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HAY6449380.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            9265..10539
                     /gene="purD"
                     /locus_tag="JOX41_001636"
     CDS             9265..10539
                     /gene="purD"
                     /locus_tag="JOX41_001636"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HAY6449381.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            10661..11575
                     /locus_tag="JOX41_001637"
     CDS             10661..11575
                     /locus_tag="JOX41_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HAY6449382.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(11708..13273)
                     /locus_tag="JOX41_001638"
     CDS             complement(11708..13273)
                     /locus_tag="JOX41_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAY6449383.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(13266..14717)
                     /locus_tag="JOX41_001639"
     CDS             complement(13266..14717)
                     /locus_tag="JOX41_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAY6449384.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(14731..15747)
                     /locus_tag="JOX41_001640"
     CDS             complement(14731..15747)
                     /locus_tag="JOX41_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAY6449385.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            15967..17055
                     /locus_tag="JOX41_001641"
     CDS             15967..17055
                     /locus_tag="JOX41_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAY6449386.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            17109..18635
                     /locus_tag="JOX41_001642"
     CDS             17109..18635
                     /locus_tag="JOX41_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HAY6449387.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            18637..19842
                     /locus_tag="JOX41_001643"
     CDS             18637..19842
                     /locus_tag="JOX41_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAY6449388.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            20099..21076
                     /gene="guaC"
                     /locus_tag="JOX41_001644"
     CDS             20099..21076
                     /gene="guaC"
                     /locus_tag="JOX41_001644"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HAY6449389.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            21340..22764
                     /locus_tag="JOX41_001645"
     CDS             21340..22764
                     /locus_tag="JOX41_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAY6449390.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            23225..24334
                     /gene="pdhA"
                     /locus_tag="JOX41_001646"
     CDS             23225..24334
                     /gene="pdhA"
                     /locus_tag="JOX41_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HAY6449391.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            24337..25314
                     /locus_tag="JOX41_001647"
     CDS             24337..25314
                     /locus_tag="JOX41_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HAY6449392.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
BASE COUNT         8201 a         4317 c         5696 g         7144 t
ORIGIN      
        1 caaaaaagaa gcagatccgt tagcggttct gcttctttta gtttattata ttttcttatc
       61 aataatagga acctgatttt aaaagcggct acctctttac cgtgcctctt tacatacaaa
      121 aaatagagga attaagcgta aatggcttgg ctattataac taaaatgctg gttatggaga
      181 tgttgcagca agttttcgag aaaagcgtat tccatctctt gtccattgaa taagatctgg
      241 atacgataat gatttttgaa acgcttctgt tcatgaatct gactgattga aagttcgcct
      301 ttgtgttctg tctgataaag aaaagtcctt ttacggcatt cagcacagcg cttggttgct
      361 cggcggattt ttcggaatgt ataaaaacta gtatctttat tgcataaata aacgtctttg
      421 atcgacagca aatcattata tagacaggaa cgttcttcag ctgttaattc tgataaaaaa
      481 agctgacctt gttttattgc atcttccatc ggcaagtgcc tcctcgaacc cattatccaa
      541 atttttagtt aattctaata taccatcatt aagtataaat gtaaacgctt gttgatggta
      601 taagattttc gtttctgata aaacacgaac attaaaagaa tctaatgcct taaatgtaca
      661 tatttttgtt gatttataaa aagatgattg ctaaaattta aagtgaaaaa acgaacaaaa
      721 aacgatgtat ttgcttttaa tgtaaataaa aaggagagac gtacatggag aagaaagaac
      781 ttttgtatga aggaaaagcc aaaaaaatat atcttacttc tgatgagaac ttgatttgga
      841 tagaatattt agatcaagca actgcgttga atggcgcgag gaaagaccag ataagtggaa
      901 aaggagaatt gaataatcaa atcacaagtg caattttccg ttatctgact caaagaggaa
      961 taaaaaatca ttttattgaa caattgtcta aaaccgaaca attagcaaaa aaagtacaaa
     1021 ttatccctct ggaagtggtt atccgaaata ttgcagcagg aagtttctca aaacgtctag
     1081 gtgttcccga aggtaaagaa ttcatcaaac caatcattga attctactat aaggatgacc
     1141 agttggatga tccatttatc aatgaagagc atatctattt cttacaactt gcaaagccgg
     1201 aagaaatcag tgagctgaaa gcccaagcgt tggctattaa tgaaattttg accgaattat
     1261 ttgctaaggt cggtttggtt ttagtagatt tcaagctaga atttggccgg tcgaatggac
     1321 aaattttgct tgcggatgaa gtaacaccgg atacttgccg attatgggat gaacgtacga
     1381 atgaacatat ggacaaagac gtttaccgca gagatctagg tgatttgatc ccagtctatc
     1441 aagaagtata taaccgtcta tcggaactaa ctgaagaaaa ggagcgagta tgatgtattt
     1501 cgtaaaagta tatgtaacct ataaagattc agtgttagat cctcaagggg aggcagtaaa
     1561 aaaagcagtc catcgtatgg gatatgaaac aatcgaagat atccgaatag gaaaatactt
     1621 tgagatacaa cttgctgatg cagaagaacc aatcgataca gtgattgaaa cgatttgtga
     1681 caagctgctt gcaaatgtaa atatggaaac ataccgatat gaaatcaaaa aaatggagga
     1741 agtataacat gaaatttgcg gtcatcgttt ttccaggttc aaattgtgac gcagatatgt
     1801 tatgggcagt tcgcgagatc atgggcgctg atgccgaatt tgtacggcat gatgagtcct
     1861 ctttagaagg atttgatggg gttttactgc cgggaggatt ctcctatggt gactatttga
     1921 gatgcggtgc gattgctcgg ttttctacaa tcatggaaga agtgattcgt tttgctgaag
     1981 aagggaaacc agtattcggt acatgcaatg gattccagat attgacagaa gcaggacttt
     2041 tgccaggtgt actgagacga aatgagtctt tgcattttat ttgcaaaact gtaccattga
     2101 aagtcaaccc caagacggcc tttacttcag agtatgaagc cgacgaaata atctatcttc
     2161 cagttgctca tggggaagga aattatttct gtgacgaaga aacacttcaa gaactaaaaa
     2221 aaaataatca gattgccttt acttataatg acaacatcaa cggcagcgtg gaaaacattg
     2281 cagggattac gaacaaagca gggaatgtgt taggaatgat gcctcatcca gaacgtgcag
     2341 tagaagactt gctaggatca gaagatggga aacggttctt tgcttccatt ttaaaaaact
     2401 tcggaaaggt gaccgtatag atgaaaacat tgaaagaacc gacagctgaa gagatcaaga
     2461 aaaaaagaat ctatgccgaa tggggattga ctgatgaaga atatcgaatg atcgaagaag
     2521 atatcttagg aagaatgcct aattatacgg aaactggact gttttctgtt atgtggagcg
     2581 aacattgttc ctataaaaat tctaaaccgg ttctacgcaa atttcctact agtggacctc
     2641 atgtgttgca aggccctgga gaaggcgcag gcatcgtcga catcggtgat ggactagcag
     2701 ttgtcttcaa agcagaaagt cacaatcatc cttcagccgt ggagccttat gaaggagctg
     2761 cgacaggagt tggcggaatc atcagagata ttttcagcat gggggctcgt ccaattgcgt
     2821 tgctagattc attgaggttc ggcgaattag ataatccaag aacgaaatat ttactagaag
     2881 aagtagttgc aggtatcggc ggatacggca attgtatcgg cataccgact gtaggcggcg
     2941 aaattgcatt tgatccttgt tatgaaggaa acccattagt caatgcaatg tgcgtaggtt
     3001 tgattgaaca caaacatatc cagaaagggc aagccgctgg cgtcggtaat tcgatcatgt
     3061 atgtaggtgc aaaaacaggt cgcgacggta tccacggagc aacttttgcc tcagaagaat
     3121 ttaatcaaga agaagaacag caacgttctg ctgtacaagt aggcgatcct tttatggaaa
     3181 agctgctgct tgaagcgtgt ttggaattaa tcttgcatca ttcggattct ctaataggta
     3241 tacaggatat gggagcagca ggacttgttt catctagtgc ggaaatggct tcaaaagctg
     3301 gctcaggact tatattgaca ttagatgaag tcccacaaag agaaactggg atgacacctt
     3361 atgaaatgat gttatcggaa tcacaagaac ggatgttgat ttgtgttaaa tcaggagagg
     3421 aagaaaaaat ccaagaacta tttcagaagt atgatctaga tgcagtcact atcggtaaag
     3481 taacagacga cgggcaatat cggctatatc atcaaggaga agaagtagca aatctgccag
     3541 tcgatgcatt agctgaagat gcaccagttt atcataaaga aatgaaagaa ccagctcgaa
     3601 tcgtagaatt tcagcagtta gctccttatc agccagttat cgaagaacct ggacaagtat
     3661 tgcttgatct gctgcagcaa ccgacgattg cttcaaaacg ttcaatctac gaaacttatg
     3721 attcacaagt acaaaccaat acagttgtcc gtccaggaag cgatgctgct gtgatgaggg
     3781 ttagagggac gaataaagcg ttagctatga ccacagactg caacgcgcgc tatctgtatt
     3841 tggatccaaa aatcggagga caaatagcag tggcagaagc tgctagaaat attattgcta
     3901 gcggtggtaa gcccttggcg atcaccgact gcctgaacta tggttctcct gataaaccag
     3961 aagttttttg ggaattatcg acttcagctg acggaattgc tgctgcgtgt gaaacgttag
     4021 gaactcctgt tatttcagga aatgtctctt tatataatga aacggatggt caagcaatct
     4081 atccaacacc aatgattggt atggtcggat tgattgagga tcataaacat atcactactc
     4141 aggaattcaa aaaatcaggg gatctaatct atatattagg taagacgttt gcagattttg
     4201 atggcagtga attacaaaag atgcagcttg gaagaatcga aggtgtgatc cgaaactttg
     4261 atctatccat tgaaaagaga aaccaagagt tagtattgac agccatccaa aacggattga
     4321 ttgaaagtgc tcatgactgt tcagaaggtg gcttggcaat tgcactggca gaatcagctt
     4381 tcaaacatca gctagggata tctgtacagt ttgaattgtc ctctgctcaa ttatttgcag
     4441 aaactcaatc aagatttgtg ttgacagtcg caccggaaaa taagacacga ttcgaagaaa
     4501 tgatgggaga tgctgctgtt ttagcaggta aggtgacgga tgaagcgata atcgaaattt
     4561 cagcaactga cggtcagatc aaaatagaaa ctgcagtagc aagaaagtgc tgggaggatg
     4621 caatcgtatg tcttatgaag tgaagagttt aaatgaagaa tgcgggatct tcggtgtttg
     4681 gggtcatcca gacgccgcta gtgtggcata cttcgggctc catagtcttc agcatcgagg
     4741 acaagaaggt gcaggtatcg tgtccaatga tcgaggaaag cttaaggggc atcgagattt
     4801 ggggctgctt tctgaggtat tcaaagatca aagaaaattg cagcagttaa caggagaagc
     4861 tgcaatcgga catgtacgtt atgcaacagc aggcaatgga agtgtggaca atattcagcc
     4921 ttttctattc aaatttcatg atcagtcgat cggcttagcg cataatggta acttgatcaa
     4981 tgctcgttcc cttagaaaag agttagagga aaatggggcg atcttccatt ctaactccga
     5041 tacggagata ttgatgcatt tgatccgacg aagtgaagaa acagattttt taaataaatt
     5101 aaaaagtgct ttgaatgaag tcaaaggtgg ctttgcctat ttattaatga cagaaacggc
     5161 aatgattgcc gctttggacc caaatggttt tcgtccatta gcaatcggac aaatgaaaaa
     5221 cggagcatac gtgattgcct cggaaacttg tgcattagaa gttattgggg cacgttttat
     5281 aagagatgtc cagcctggtg agatagtgat catcaatgac gaaggaatcc agattgattg
     5341 ctttacgaag gacacgcagc tttctatttg ttcgatggaa tatatctatt ttgccagacc
     5401 agattcaaac atcgcaggga tcaatgtgca tactgcacgg aaaaatatgg gacggaattt
     5461 agcgaaagaa tcgccagtaa aagcagatat ggtcgttggc gtacctaatt cttctttgtc
     5521 agccgcaagc ggttatgcgg aagctagtgg aatcccttat gaaatcggat tagtaaaaaa
     5581 tcaatacatt gcccgaacat ttatccagcc aacgcctgag ctaagagagc aaggtgttcg
     5641 aatgaaatta tctgctgtac gaggagtagt ggaaggtaaa aaggtgatta tggtcgatga
     5701 ttcaattgtt cggggtacga caagcagacg gatcgtccat cttttgaaag aagcaggggc
     5761 aaaagaagtc catgtgagga ttgcttctcc tcctttgaaa tatccatgtt tttacgggat
     5821 tgatattcaa acgcgtaaag aactcattgc ggcaaatcac acgattgatg aaatcaaaga
     5881 atgtatcggt gcagattctt taggtttttt aagtgaagag ggtctgatcg aatcgatcgg
     5941 tctggaaaaa gatgctccgt attcaggatt gtgtatggct tatttcaacg gagattatcc
     6001 gacgccgtta tatgactatg aagaaaaata tcaggaatca ctaaaagaaa aagtatcgtt
     6061 cttttaaaag cagaccaaga agggagtata tgaattcaat ggcaaatgca tacgcaaaag
     6121 ctggcgtaga tgtcgaagct ggatatgaag tagtagaacg gatcaagaag catgtcaaaa
     6181 aaacggaacg tttaggtatg atgggcgcta taggaggatt cggcggttgt tttgatttat
     6241 cggtctttca attaaaagag ccagtccttg tctcggggac cgatggcgtg gggacgaaat
     6301 tagcagtggc aatcgaagca gacaaacacg atacaatcgg gatcgactgc gtagcgatgt
     6361 gtgtcaatga tatcttagca caaggcgcag agccgttata tttcttagac tacttagcaa
     6421 cggggaaaaa tgatccgtta cgtttggaaa atgtagtaaa aggtgtagca gatggatgtg
     6481 ttcaaggaaa tatggcgctg attggcggag aaacagctga aatgcctggt atgtactcag
     6541 gtaatgatta tgatctagcc ggatttgctg tagggatagc tgaaaaatct caattattga
     6601 caggagaaac gatcaaccca ggagatgtgt tgcttggaat agcatctagc gggattcatt
     6661 caaatgggta ctctcttgtt cgcaaaattt tctttgagca gcagcagttt tctttatcat
     6721 caaaactgcc agaattgaaa aaaacacttg gcgaagaatt gcttgagcca acgaaaatct
     6781 atgtttcttc cttgcttccg ctgatcaaag aaaagaaaat aaaaggagct gcacatatca
     6841 ctggtggagg gtttgtagaa aatatcccgc gaatgttacc agaatctatg gctgcacaaa
     6901 tcaaacttgg ctcatggccg attcttccaa tattcggctg tttacaaaaa tatggtgaaa
     6961 ttcctgagat ggagatgtat gaaatcttca atatgggcat cggtatggtc ctggcagtcc
     7021 aagaatcgaa agtaaaagaa atagtacacg aaattgagca agctggcgaa aaagtttatg
     7081 aaatcgggaa agtgatcgcc aaagaaaaac atcgtgtggt gtttatagga gaagaacgat
     7141 gagaatcgct gtttttgctt ctggaaacgg aagcaacttt caagcgctag ccgattatct
     7201 atcgaaaaaa ggattggaat cttcgattga ctggttgttt tgtgatcagc ctgaagcata
     7261 tgttttgaaa cgtgcaactg cgttgagtgt accggcagat tgtttttcac ctaaagaatt
     7321 tgattcaaaa aaagagtatg aagaagcaat tttgcataaa ttgaaagaaa aaaagatcga
     7381 tttgatcgta ttagctggat atatgcgaat cattggaccg gtattgctga aaaattatga
     7441 taaaagaatc atcaatatcc atccgtctct tttacctgcc ttccctggtt tgcatggcat
     7501 acgtgatgcc tttgaagctg gagtaaaaga aacgggtgtc acaattcatt atatcgacca
     7561 aggtgtagat actggaccaa tcatccggca ggaaaaagtg agaattgaac aggaggacac
     7621 gttcgattct ttagaagaaa aaatccatag agtagagcat cgaatctatc cagaagtgat
     7681 tagtgaaatt attgaaaatg gaggctatct gaaatgacaa gagcattgat cagtgtatca
     7741 gataaaactg ggattgtagc attcgcccaa ggtttgattg aacaaggagt agaaatcatt
     7801 tcaacaggag gaacaaagca tgcgttggat aaagctggga tcaaaacgct ttcgatcgaa
     7861 gaagtgacag ggtttcctga aatgatggat ggccgtgtca aaacacttca tcctaaaatc
     7921 catggtggtc ttttaggaag acgcgatctc cctagccata tggaggcaat ggaaacggaa
     7981 aatatccaac caatcgactt tgtttgtgtc aatttatatc ctttcaaaga aacgattatg
     8041 aaaccagatg tcgaaatagc agaagctatt gaaaacattg atatcggtgg tcctagtatg
     8101 ctccgtagtg cagcaaaaaa ccatgaattt gtcacctctg ttgttgatcc atctgactat
     8161 gaagaagtac tttcagaatt acgtcagtat gggcatactt cactttcttt cagacaaaaa
     8221 ctagcggcaa aagtctttcg tcatactgcg gcatatgatg cactgatcgc tcaatactta
     8281 acggattggg tggaagaaaa agaaccggaa aaattgacac ttacgtatga acgaaaacaa
     8341 acgcttcgtt acggtgaaaa tagccatcaa gccgctgcct tttatcagtc cgctcttctg
     8401 gaaaaatatt cgatcgcagc agcaaaacaa ctccatggga aagaactttc ttataataat
     8461 atccgagatg cagatgctgc gctacggatc atgaaggaat atgacgagcc aacggtagtc
     8521 gccttgaaac acatgaatcc ttgtggtatt gggacagcat ctacgatttt agaagcgtgg
     8581 gaagcagcgt atgaagcaga tcctgtttca atctttggtg ggatcatcgt tttgaatcga
     8641 gaagtagatc tgccaacagc agaacagatg cataagctgt ttctagaaat catcattgcc
     8701 ccttcttata cacaagaagc tttggaatta ctgcaaaaaa agaaaaacat ccgattactg
     8761 acagtagact ttgcgcagga agaaaatcaa aatcgagaag aaacggtctc agtcttaggt
     8821 ggacttcttg tacaagatca agatctggca atagaaaatg aagaagagtg gaaagtcgtg
     8881 acaaaacgta agccgactcc agcagaagca aaagcattag cgtttgcttg gagagctgtc
     8941 aaacatgtga aatctaatgc gatcgtactg gcaaacgaac gtcagacagt aggaatcgga
     9001 gccgggcaga tgaatcgagt cggttcagta aaaattgcga ttgaacaagc gcaagagaaa
     9061 atggaaggtg cagttttagc tagcgatgct tattttccaa tggatgattc ggttgaatat
     9121 gcagccaaac atggtataaa agcaatcatt cagccaggag gaagcatcaa agaccaagat
     9181 tctattgata tggcgaataa atacgatcta gcaatggtct ttactgatgt tcggcatttt
     9241 agacattaga gaggagtcgg ataaatgaac attttggtga tcggtgcagg tggtcgtgaa
     9301 catgcaataa gtaaaaaact tttagccagt ccgaaggtgg atacggtgta ttgtgcgcca
     9361 ggaaatccgg ggatgacaaa agatggtatc aattgtgtcg ctatcagtga gcgagatcat
     9421 tcagcgttaa tccattttgt taagaaagag gctattgatt ggagtatcgt tggtcctgaa
     9481 gttcctttgt taaatgggat cgtcgatgat tttatggcgg aaggattgaa aatcttcggt
     9541 ccgacaaaag cagcagctct gatcgaaggt tcgaaaagtt ttgctaaaca attaatggat
     9601 acttatcaaa tcccgacagc taaatccaga agttttgaat gttacgaaaa agcagcagcg
     9661 tatatcaaag aaaatggtgc gccaatcgta gtgaaagcgg acggcttagc agctgggaaa
     9721 ggtgtagtcg tggctaccac agtgaaggaa gcgctggatg cggcagaaca aatgttgaac
     9781 cagcatcgat ttggggatag tagcaaaaaa atcgtcgtag aagagttttt ggcaggagaa
     9841 gaattctccc ttttggcgtt tgtccgtaat accaaggtgt atccgatggt catttcgcaa
     9901 gatcataagc gggcatttga taacgataaa gggccaaata caggcggaat gggtgcttat
     9961 tcgccagtac cgcaaatttc aaaaaagatg attgaaaaag ctgtggaaga agttttaaaa
    10021 ccagcggctt tgggaatgaa agaactagga cgctctttca cgggtgtttt atatgcgggt
    10081 ttgattgcta cgaaggaagg accaaaagtg atcgaattca atgcgcgttt cggtgatcct
    10141 gaaacgcaag tcgttctttc tcggttgaag agtgactttg cgcaagtaat cgatgattta
    10201 ttagagaatc gtacagtaga gttaaagtgg cagcaagaag gatacaatgt aggcgttgtg
    10261 gttgcagctg ccggttaccc cgaagaatat gagacaggaa tggttctacc agattttctg
    10321 gaagaagagc tttctgttta ctatgctgga gtttcctcaa ataacggcaa actagttgga
    10381 gcaggaggac gtctttattt agtagaagca tacggtgaga cgatcaaaga agcacagaaa
    10441 aaaatttaca ccgcgttaat ggataaaacg acagatggaa cattttatcg tacagatatt
    10501 ggagaaaaag ctgccaatag cgaactgatc gtgaagtaaa tcagctgctt ccatttataa
    10561 aaaatacaac aaacataatc ggaagcgccg attttagtga agccttttca taaagagtgt
    10621 ggtacacttt tgttgtgtat ataaataagg aggagttcag atgaaaaaaa ttcaattagg
    10681 tacttctgat cagaaagcag ctgcagtgat cttaggctgt atgcgtatca acaatgcgga
    10741 agatccagta aaagtgattg agacagctta tgaaaacggc attgattttt ttgaccatgc
    10801 agatatttat ggaaacggtg aatgtgaaga aatctttgca gatgctctag caaaaacatc
    10861 aatcaaacga gaagatcttt ttattcaaac aaaatgtgga atcgttccag gtgtgatgtt
    10921 tgatttttct aaaaaacata tcattgaatc tgtagaaaaa agtttgaccc gtctgaaaat
    10981 ggattatgtg gatgctttac ttcttcatcg tccagataca ttggtagaac cagaggaagt
    11041 agctgaagcg tttgatgaat tggaacggtc aggaaaagtt cgttattttg gcgtcagcaa
    11101 tcaaaaacca atgcaaatcg aattgctgaa aaaatatgtt cgtcaaccat tagtagctaa
    11161 tcagctgcaa tttggcttga aacatactgg aatgatcgat caagggattc atgtcaatat
    11221 gacagatgaa gcaagtatcg atcatgacgg tagtgtactt gattattccc gattgcatga
    11281 tatgacgatc caagcatggt caccatacca gtatggattt tttgaaggtg tatttatcgg
    11341 gaacgaaaaa ttccctgaat taaaccaaac attagaagaa ctagcagcta aatatcaaac
    11401 gacaccaact ggcttggctt ctgcttggat tttacgccat ccagccaata tgcaagtgat
    11461 cgccggtacg atgaacgtag ggcgaatcaa ggaaatcgct caagcttcag aaattaatat
    11521 gtctcgggaa gattggtacg aattgtaccg tgctgctgga aacattttac cttaaagatt
    11581 gtcataagca ggtcaaaagg gctataaatt aaaaagacag aataacttga aagctgtttt
    11641 cagcttcgag atattctgtc tttttttatt gcaaatggaa agagtatcat tgtacggatt
    11701 tcgtttatta gttatttttg tttttaagga aaagctgtgt ccgatattct tttggagaaa
    11761 tcccttgttt tttcttaaat aaataactga aatagttagg gtcattataa ccaatttcaa
    11821 aagcaatatc tgaaatacga tagtctgatt gctgcaataa tttttttgct aattcgattc
    11881 tttgttctgt cagataatcg atgaatgttt ggttaaacga ttgagaaaaa atcgtactga
    11941 aatgagaggg acttaatgca acttgttgag cgacccaagt taaggacata tctggatcgg
    12001 taaaattttc tttgataaaa tccaatgcat ggttcaaaat tggctgatat ttgttccttg
    12061 aaggctgtga gggcagagca gttaagaaag aaatgaacat ataaactgtc gaacggtaaa
    12121 gcgagtcgtc ggcgctgatt gctaagcgtt gactggtgga tgtgcaatga accatttctt
    12181 gcgggatttt cttttctttc aggcagacat gctggagtag cttagtcaag acaaataaac
    12241 gatataatcg tgttcgagtt ggtgtgcctt gtggtttcgt caagtgttcg atgtacttag
    12301 atacttcgtt tttcgataat gaagacaaat caagtgagag gtcaaagtaa aagacagaat
    12361 caactggaag tttcgcttct tgaatcaaat cctcatagct gataatttgt tctttaaggg
    12421 aactggcggt ttcaagtatc atctgcgtga tctcaaaaga tgcaggtaat tcgctgattc
    12481 tttctgcgac aggaccaatg gcgacagaaa aattattttt ttgtcccttt tctaattcat
    12541 ggaccaacgt ttgggctacc tgataactgg tctcgatcac attttcttca agagaatcaa
    12601 ctattaaaaa tttgatgaat cgagaggaaa cagcagagaa gatcacttgt tgattctccc
    12661 taaataaaaa cttcaaataa tcactgagat gagcgtaatc ttcaaagtct gtactgactt
    12721 ggtttgctgc taataatacg gtcatttttt tccctgctaa agagcgattg aaagattcag
    12781 caagtttcaa tgtttcactg atcgtaagtg agcctttgaa caaaccgttc aagaaatgat
    12841 tttttttcaa ttcgaaaaca agatcagaag aagtgtgcgt ttctttttgc tgcaaatcta
    12901 aagcagttac tgctttttct attgcttgtt tcaattcgct acttttaatc ggtttaagca
    12961 gataatcatc tgcctgtacc tggattgctc ctttcatata atcgaaatcg tcgaatccac
    13021 taataaatat gagacgagtc caaggaagta gtttccttgc ttcttttgaa aaagtcaacc
    13081 cgtccatgaa aggcatttgg atatcagtca gaatgatgtc gggctgtaag tcgataattg
    13141 aagacagtgc catctcacca tctccagctt cgccgacata agtgattgga taataagaac
    13201 caaggacagt tatttgttcc cgcaagttat tgcgaatgag gtattcgtct tcgatgataa
    13261 aaactttata catgtttgtt tcctccaatt gttttgggag atagagggat catcagtgtg
    13321 acagttgttc cttctcggta tttgctgtca atcgtgatag gtttttgatc atttccgtaa
    13381 taaagaagga gacgcttgtt tacgttgtaa agtccgtagc cgatactgaa atctgaatcg
    13441 atccctttgg ctaactcttt acgtatttct gccagttttt ctgcagggat gccaatcccg
    13501 ttgtctataa ctttgaattg gatcatctca tcaattttgc atgtggtaat acgaataaat
    13561 cctttgtgac ggacgtactt cgttccatgg tatacagcat tttcaatcaa tggctgcaag
    13621 atcattttta aaatagaaac aggaaaaagt gtttctggta tatcgatctt atagtcaagc
    13681 atatggccgt atcttatttt taagatgact agataatcat tgatatggct aatttctttt
    13741 tcaagaggaa tccagtcttg tcctttgctt aaagacgtac gaaaaaagcc ggaaagtgca
    13801 tgggtcatag tcagagcttc ttcaaagcag tcttgttcga tcaaagaaat aatggcatcc
    13861 aaactgttat aaataaaatg gggagtaatc tgagcttgca atacacgaac ttcactttgt
    13921 gctaaatggt attgtttcaa agcgttctcc cgtaaagact ggtttagatc ttccgccatt
    13981 ttattcatgc tagcggtaag tgtttgtaat tccagtgttt ccggcagggt taaacgaaag
    14041 ccaaggttcc ctgaagaaag ttgttctgac atctcgatca gctgattgat cggttcttgg
    14101 acctttctct ctaaaaagcg acgattcttt ttcgcataga aaaaaatggt actaagaact
    14161 ccaagttcca ctattgttaa tagaatgagc gagcggacaa gtgtcgtatt ttttttgctt
    14221 gctaagtcga tctccacacg aacaaaatct tgtaagatat ctgacagcag ttgagtgaca
    14281 gaatctacct gattgatgat ctcttcattg gtatccataa aatcttttgc caagatatta
    14341 ttgatcagct cgttttgata atcttccagt gtatcgatcg tacgtagcga tacatctaac
    14401 gtactaattt ctttaagtgt atttgtatta tttttgatct ctcgaatatc attcctaagt
    14461 tcttctagga tattttcctc attgaactca tctacggtta cttggccaga aatcaagtcc
    14521 cacatacttt ccaaaacttt ttgatcaacc ttcaaagcaa ttgcatctgc tttttggata
    14581 tttgcgatcg tctgttgata aatcaaaagc tgttgcgaat ataacagtat gctcagtagc
    14641 aaagggataa cagcaaatag aagcatggct ttgtttgctt gggcaaaaat ctgttttatg
    14701 cttaaatttt ttgtcatgat acttctccag tcaataattt ctggttggga tgttagctat
    14761 attctgctgg gaaaagacag tctcggaaat aaaaatatct ttaggtaatg tttttcctgt
    14821 ttgaatattt ccaaaataac gagtaacggt attggctaca taccagccga catcaggttt
    14881 acactcgact acacaattga cgattcctga gcgtagcttc tcgatcatat cttcttgtcc
    14941 atcaatagtt acaatgatca aatcttctcc aggtttgatt gatgtttctt ttatcgcagc
    15001 taaagcaccg tgagtcattt catcactatg gctgtataat acatcgattt cggataaatc
    15061 atttgtttct aaatatcgtt tcatctggtc ttttcctttc atccgaataa aatcaccgac
    15121 aattcggtga acaatagtca tcggaggttt atggtcgatg gttccatctt tttttagggt
    15181 tggtttacga ttgattgatt ccaaaaatcc ttcggagcgt agcttggtcg gtgtggagtt
    15241 ctctgaacca gcaagttcta ggattctgat ttcctgtttc tttgaatttg tgaagtgatt
    15301 gctgacaaat aaacccgccc gatttccttc tgctttgaaa ctggggccaa tgtgggtgac
    15361 gaaaagctcg ggatcattcg tttgaatatg tctgtcgaca agtatgacag ggatccctgc
    15421 tcgctttgct tcttttaata cagagtccca cccggattct tgcaaaggag taaaaatgat
    15481 catatccact ttataggcaa tgaacgtccg tatatcttgg atttgccgtt cctgattcat
    15541 gtagccattt cggtagagaa cttggtaatc ttctttttca agcgcagtga taattgattc
    15601 agtatgcttt ttccgccagc tactctccgt tcctgattgc gaaaaaccaa cgactagtgg
    15661 gtcaggtgct tcctttgtat taggtgtaca ccccatcatt tggtaagcga ttacaacaag
    15721 ggctaaaaaa aataaaacac gtttcacttt aaatcactcc atctggattt gttagtacta
    15781 tcttatcaga taaaagggaa aatcaaagtc aaaaggaatc aatcgaaaaa aatccaagaa
    15841 acttaaaaaa atccaagaca aaaaaagtac acctaaaaaa tttaaagtaa atcccataaa
    15901 aaaatcaatg ttaacgcttt ctttattagc tatactcggt gtatcaattg aaatggggga
    15961 taaaaaatga aaaacaaatt tagaaagatt gttgggacta tcgctatttt gaccgcaagc
    16021 attctattaa gtgcgtgtgg caattcagga tctgcagatg atagtacggg gtatgtagga
    16081 atcgctatgc cgaccaaatc agcagaaaga tggatcgctg atgggaacaa catggtctcg
    16141 gaattagaaa aactgggtta taaaacagat cttcaatatg gagaagataa agtagaaaat
    16201 caagtagcac aaatagaaaa tatgattaca aaaggggtag atacacttgt gattgcttct
    16261 atcgatggtt cggctttaac tgatgtgtta gctaaagcaa aagaagcaga tatcaaggtg
    16321 atcgcctatg atcgtttact gatgaattca gaaaatgtcg attattacgc gacttttgat
    16381 aattttggag taggtgtatc gcaagcagct tatattgaag agcacttagg attgaaagaa
    16441 ggaaaaggac cattcacgat tgaattattt ggtggctcgc ctgacgacaa caacgcacta
    16501 atcaattaca acggagtgat gtctgtttta caaccatata tggacaacgg tcagttggtc
    16561 gtgccatctg gacagacgag tttcagtcaa atcgctacgc ttcgctggga tggttctacg
    16621 gcgcaagcaa ggatggataa tctgttaagc gcaaattata ctgaccaaac attggatgct
    16681 gttttgtcgc catatgatcc aataagttta ggaatcattt cgtcattaaa aggcgtgggg
    16741 tatgggagtg aaagtaaacc tttacctgtg attactggac aagatgcgac agttgctggc
    16801 gttaaatcga tcattgccgg ggaacaaaca caaacgatct ttaaagacac acgtatctta
    16861 gcaaaaaata cgattgaaat gatcaaagca atcagtgatg gagaagaggt tccggtcaat
    16921 gatactgaaa cttatgataa tggggtgaaa actgtcccta cgtatttagc aaatacagta
    16981 tctgtcgata aagataatta tcaagcagag ctgatcgaca ccgattatta taaagaatcc
    17041 gatctgaaaa attaagagga accaaacaag gaactaaaga gatctaagtc agagagagga
    17101 taagaattat ggcggattgt attttaaaaa tggcagatat caccaaaaaa ttttctggaa
    17161 tccgagcgtt agattgcgtg aatctgatga ttgaacgtgg ggaaatccat gcattgtgcg
    17221 gagaaaacgg agcgggaaaa tcaacattga tgaatgtctt gagcggcttg tatccatatg
    17281 gctcctatga cggggaaatc ttttatgatg gaaagctgtg tcaatttaaa gatttgaaag
    17341 atagtgaaga aaaaggcatc gtcatcattc atcaagaatt agcactaagt ccttatcttt
    17401 caataaaaga gaatattttt ctcggaaatg aacaagcaga aagaggcgtg attgattggg
    17461 aactgacaga aaagaaaaca tatgaactgc tgaataaagt cggtttgtct atcgacccga
    17521 atcttctagt atcccagatt ggcgtagggc aacagcaact agttgaaata gctaaagcat
    17581 tatcaaaatc cgtccgtctg ttgattttgg atgagcctac cgctgcattg aatgaagaag
    17641 aaagcgcgaa tttgctgaga ttgatccgag agttgaaaga gcaaggtgta acctccatca
    17701 ttatttcaca taagctgaat gaaatcgtgg atatcgcaga tcgaatcacc attttacggg
    17761 atggacagac gattgagaca ctagaaaatg aaatgatcag cgaagagcat attattcgcg
    17821 gaatggtggg cagagattta gttgatcgtt atcctgaaag aaaaccggat attggagaag
    17881 tttattttaa agtagaagac tggacggtct atcaccctct tgatcacgag cgaatcataa
    17941 acgaccacat caacttgcat ttgaaaaaag gagagattgt aggaatagct ggactgatgg
    18001 gagcgggcag aactgaattc gctatgagtc tatttggaca ttcttatgga agcaagatat
    18061 ccggacgtat attaaaggaa ggggcagaga tatcagttaa gaccgttcct tcagccattg
    18121 caaacggact cgcttatgtc tcggaggacc gaaaatcttt aggactgaat ctgctgatgg
    18181 atattcggga aaacgtgacg ctgagcagtt tggataaaat aagtcaaaaa ggagtattag
    18241 ataaagaaaa agaagtaact gaggcagaaa atttccggaa aaagatgcgt ataaaaacaa
    18301 actccatcca tcaaattgtc agtagtctta gtggtgggaa tcaacaaaaa gtcgttttat
    18361 ccaagtggct gatgacacaa cccgatattc tttttttgga tgagccaacc cgtgggatag
    18421 atgttggggc aaaatatgag atctacacga ttatcgaaga aatggcagca aatggcaaag
    18481 ctgtctgtct tatctcttct gaacttcctg aaatattagg gatgtgtgat cgaatctata
    18541 cgatgaacga aggacgtatt acaggagaag tctcgcgaga agatgcagat caggaagtct
    18601 tgatgaaatt aatgacgaaa gaagaggtgg gttaagttgg aacaggcaaa aaatcttacg
    18661 gataaaaaag agaaaaaact aaatttgaaa agtagagcag ctgatctttt tggtcgctac
    18721 agcatggtga tcattttagc gggactactt attgcgtttc aattgatgac ggatggtatt
    18781 ttctggcgtc cattgaatat aactaacctt gttctgcaaa atagccatat attagtacta
    18841 gctgcaggga tgttattagt tgtgctctta ggtcatgtgg atttgtcggt agggtcagtg
    18901 atggcgtttg ttggtgcaat tgcgggcatg atgatggtca atcgccaaat gaacccgtgg
    18961 atgacagtta tcgcatgtct tgcagtaggc gggctgatcg gcgcatggca aggtttttgg
    19021 gtagcttatg cagggatacc ggcgtttatc gtgactttag caggattgct gatgtttcgt
    19081 ggactgacac aagttgttct aggaggccaa tctctagcac cttttccagc tgttttccaa
    19141 aaaatgtcta cgggttattt accagactta agcgaaggaa gcagccttca cttcttgaca
    19201 ttgattttag gaatgatcat cacgatcgtg ttagttgttg gtcaatggcg aacaagaaat
    19261 cgtcggaaaa atcatttatt tgaagtggaa tctccaacag ctttcttggt aaaggcggta
    19321 tttacagcag tcgttgtact aggaataact tatatctttg cctcttatca agggtatccg
    19381 attattttga tcattcttgg tttgatcgtt gcagcatatg ggtttttgac aaataaaaca
    19441 gtagcaggtc gacagattta tgcgacgggc ggaaatcgaa aagcggctga actatcaggg
    19501 atcaaaacaa agcgaatcac gttctgggta ttcgtcaaca tgggagtcat ggcagcttta
    19561 gctggattag ttttagctgc tcgattgaat gcggcaacac ctcaagcagg tacatcgatg
    19621 gaactggatg caatggcggc agtatatttt ggtggtgctt cgacttccgg cggcattgga
    19681 acaatcatgg gtgcgattgt cggtggcttg gtcatgggtg tattgaacaa tggcatgtcg
    19741 attttaggcg tcggggtaga ctggcagcag gcaatcaaag gattgatctt gcttttagcc
    19801 gttgtgctag acttgtataa taagaaaaaa cgaacaacgt aggagaacgc cggttattca
    19861 gaaaaaagac tgtgacaaga catttgtcac agtctttttt tcgctaaaag cgaacattca
    19921 ttgtttcgtt tgtatagact aaaaataata tatgtttttt taccattcgt ataaattctc
    19981 tttttgctct tgattttttt gcttaattga gttaaattac atagggcgct aaaaaaagcc
    20041 ttgattaaat taataatgtt cgtgttttgc tggatgtgaa catcaggagg ataatgtaat
    20101 gaaagtattt gattacgaag atattcaatt aattcctaat aaatgtatcg taaatagccg
    20161 ttctgaatgt gatacaacgg tcacattagg taaacataca ttcaaaatgc cagtagtgcc
    20221 tgccaacatg cagacgatta ttgatgaaac aatcgcagaa ttcttagcgg aaaatggtta
    20281 tttctatatc atgcatcggt ttgatgaagc agctcgaatt ccgtttatca aaaaaatgaa
    20341 aaagcgtgga ttgattacct cgatcagtgt tggcgtcaag aaagaggaat attcctttat
    20401 agagaagttg gcagaagaat cgctaaatcc tgattatatc actatcgaca tcgcgcatgg
    20461 acatgctaac tcagttattg atatgattca gcatattaaa aaatatttgc ctgaaacttt
    20521 tgtgattgcc ggtaatgttg gtacaccgga agccgtccgt gaattggaaa atgcgggcgc
    20581 agatgcaaca aaagtcggga ttggtccagg aaaagtatgt attacaaaaa tcaagacagg
    20641 ctttgggact ggaggctggc aactggcagc tcttagatgg tgtgcgaaag cagctcgcaa
    20701 gccgatcatc gctgacggtg ggatcagaac acatggcgat attgcaaaat ctgtccgttt
    20761 tggtgcgaca atggtcatga ttggttcatt gtttgccggt cacgaggaat ctcctggcga
    20821 aacaaaagtc gaaaatggaa tcgtgtataa agaatacttt ggttctgctt cagaattcca
    20881 aaaaggcgaa aaacgaaatg ttgaaggaaa gaaaatctgg atccaacaca aaggatcttt
    20941 gaaagataca ctagtggaaa tgcaacaaga ccttcaatca tctatttctt atgctggagg
    21001 aagagatctg gaagccattc gaaaagttga ctatgtcatc gtgaaaaatt cgatttttaa
    21061 tggagacaca atctaaaaaa taaataaaat attaggatgt tgtgaaaaag ttgtcctgca
    21121 ttaagtaata agaacagcca aacaaaaata gttctttata tgttttgttt ggctggaatt
    21181 attatcgcag atacaagctt ttgaacatca ttattcagaa taagggactg tgataagatt
    21241 tttgtcacag tcccttatgt tttgcaaaaa aagtttttct tttttctcgt aaattcggta
    21301 aaatcaaaag aaaaaataga caatagaaaa gagaagctta tgtgggaaaa agtagagaaa
    21361 aaacaaggac cgatttatcg tcaaattatg gaacagatta tgagagaaat cgaaaacgga
    21421 aggatcaatc ctggaagtca acttgaatca gaacgaaaac tagggcaact ttttggtgtg
    21481 aatcgttcca ccgttgtcca tgcattggaa gagcttaggg agcttggggt actaacgagc
    21541 aaacgtggca gcggatggtt tgttaatcag actgaatggg ggaaattcgc tgttccaaga
    21601 atcgattggc ggcaaatgat ctctcctcgt tatgagcaga cggactggta tgagcaaaaa
    21661 ataagagaag caaagcagat ccaaaaaaca tcgtttcttg atttatacgc tagcgagatg
    21721 ccagatgagc ttttgccgaa ttttgagttt ccttcttatt ctcttgaaga aatcttagcg
    21781 gaagaaaaag aaatggatct tttaggctat actccgttac gtaacaaaat caaacggtat
    21841 ttggaaagta aatttgaatt ggcattttcc cccaaccagc ttcttgtgac tggtggcggt
    21901 cagcaagcaa tctttttgat tttacaaacg attctttcag ctggagaggg gatagctgta
    21961 gagtcacctt ctttttttta ccgattacct cttttcaaag cttcaggaac gcgtttattt
    22021 gggataccga tggatgaaga agggatcgac ttagaaaaac tgaaagaatc gatccataaa
    22081 aataaattga aagcagtgct tatcaacccg aattttcaaa accctacagg aaaagtgatg
    22141 agtcaaaaac gacgagaaaa gctagtagaa ttgtgtcgac agtatcggct tccaattatt
    22201 gaagacgatg tatttacgga tctttcattt ctaaaccaag aagaagtcct tcctatacga
    22261 acgattgatc cggataatgt gttatacgtc ggttcgttat ctagggtttt aggaaaaaca
    22321 acgaaaatcg gttgggtgat aggacctgag acttttatct cgcaactagc tcaagcgcaa
    22381 gaaatgatgg agttttcgat gaatatcctt acacaaatca cagtggctaa tgtatttaat
    22441 gaagcaattg atttgaaaat gcaagatgta agaaaaaagt tgaaagaaaa aagccgactg
    22501 ataagcgctt ggggagattc acaatcgttt ttcaagcttc attcaatttt aggtggttac
    22561 tatgcctgga ttacttggga tgggaaaaaa ctagaccccg aactagcaga aaaagtagta
    22621 gatatgggtc ttggaattgc accaagtcta ctttttgggc aagatataaa tggaatcaga
    22681 atcaattaca gtaggctgga tgaaaaccaa ataccgttgt tttattcaaa gatgaaaatt
    22741 ctagaaaagt ggttaacaga ataatttcac aaagtaaata gattaaagaa tataacagct
    22801 tggatttaaa tttcaagctg tttctttttt ttcggaaaaa gaatacgata taaagaaact
    22861 aagaaaaaac cattatttgt acgtccgttc acgatgtgta aataaaataa atgtttgcaa
    22921 caaaactgta taacaccaac gtttttaaat agaaacagat ggttgtaagt ttgattagaa
    22981 aatagaaaaa atgcagatga aatataaaac gctttcctta ttgtgatttt attcactaat
    23041 gctgttaata tgcggattgg cataatttcc tttcatcgtg aaaatttgtg cttttagctt
    23101 gtatttctca taaatccatg ataatttatt aatgaagacg gttaaatagt gatacagttt
    23161 tattcactgt ttcaatcgca gaatgaagag attttcttat agatgagaga ggaatgtgtg
    23221 acaaatggca aacaaaaaag caccgatcga cttccaagca ctgctagatg aagtcaatgc
    23281 agatttccca gtatatcaag cacttgatca agatggaaac gtagttaaca aagatttagt
    23341 acctgattta tccgatgatg aactcgttga attaatgact catatggtat ggtctcgtgt
    23401 attagaccaa cgttcaacag cgctgaaccg ccaaggacgc ctaggctttt ttgcaccaac
    23461 tgctggacaa gaggcaagtc agctggctag tgcttacgca tttgataaag aagatgttct
    23521 tcttccaggt tatcgggatg tacctcaact agtaaaacat ggtttacctt tatctcaagc
    23581 ttttttatgg tctcgaggac atgctgcagg taattcttat ccggaagaat tgaaagctct
    23641 accaccacaa attatcatcg gtgcacaata tgtacaagca gccggtgttg cattaggttt
    23701 gaagaaacga aacaagaaaa atgtcgtctt cacttatact ggtgatggcg gttcatcaca
    23761 aggtgatttt tacgaagcaa tcaatttcgc tggcgcttac catgcaaatg ccgtatttta
    23821 tatccaaaac aacgggtatg cgatctctac acctcgtgaa aaacaaactg cagcaaaaac
    23881 acttgcacaa aaagctgtcg cagctgggat tcctggtatt caagtcgatg gaatggatcc
    23941 gcttgcagta tatactgtat ctaaaatggc acgggaatgg gcgatcagtg gaaatggacc
    24001 agtcctaatc gaaacactga cttatcgtta tggaccacat acactatctg gtgacgatcc
    24061 aacccgctac cgtacaaaag acacagatga cgattggcag aaaaaagatc cattgatccg
    24121 cttccgtaaa tatttgacgg aaaaaggact ttggtctgaa gaaaaagaag aacaagtcat
    24181 cgaagcaact aaagaagaaa tcaaagcagc tattgctgaa gccgacaaag taccaaaaca
    24241 aaaggtttca gatttcttga aaaacatgtt cgaagtatct ccacaatcaa tcaaagaaca
    24301 aattgcaatt tatgaagcga aggagtcgaa ataatcatgg cacaaaaaac aatgatccaa
    24361 gcaatcacag atgccttagc acttgaacta gaaaatgacg agaatgtcgt tgtttttggt
    24421 gaagatgttg ggaaaaacgg aggagttttc cgggcaactg aaggattgca ggaaaagttc
    24481 ggagaagacc gagtattcga tactccttta gctgaatctg gaatcgcagg attgagtttc
    24541 ggtcttgcgt tagaaggatt tcgtccagtt cctgaaatcc aattctttgg ttttattttc
    24601 gaagcaatgg acgaagtagt agctcaaatg gctcgtacaa gatatcgaat gagcggcact
    24661 agaaatctac ccatcacaat tcgttcgcca tttggtggcg gtgttcatac accagaattg
    24721 cattcggata atttagaagg tttgatcgct cagtctcctg gtattcgagt agtgattcct
    24781 tccaaccctt atgatgcaaa aggactattg atttcttcta ttagaagtaa cgatccggtt
    24841 gttttcctag aacacatgaa actatatcgc tcattccgag aagaagtgcc ggatgaagct
    24901 tacgaagttc ctttggataa agcagcagtt actcgtgagg gaacagatgt atctattatc
    24961 acatacggag caatggtgcg tgaagcaatc aaagcagcag acaatcttgc aaaagaaaat
    25021 atatctgttg aaatcattga tcttcgtaca gttgcgccat tagatgtaga aacgatcatt
    25081 caatccgtgg aaaaaactgg tcgcgtagtt gttgtccaag aagcacaacg acaagcgggc
    25141 gttgccgcgc aagtagtttc tgagatctca gaacgcgcta tcctttcatt agaagcccca
    25201 atcggacgag tttctgcacc tgatacagtc ttcccatttg gacaagcaga aaatgtctgg
    25261 ttgccaaatg caaaagatat cgaagacaaa gtaaaagaaa tcgcggaatt ttaagaaaag
    25321 aagggacgaa acaaagtcat ggcttatcaa tttaaatt
//
LOCUS       DADLIO010000037        24392 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.037, whole genome shotgun sequence.
ACCESSION   DADLIO010000037 DADLIO010000000
VERSION     DADLIO010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24392
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.037"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(187..2532)
                     /locus_tag="JOX41_001648"
     CDS             complement(187..2532)
                     /locus_tag="JOX41_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HAY6449393.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLLFAA
                     LGIGIGAGYFAYLVEDTQLPTKKELQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIVLSAQVEKHFSKNEIITTYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSEAYYQKAQQTIQNKGYTIHSTIDKDIYAALQTGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLVGSES
                     RVSDYATTWQEGKNAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINEKITTPFKDVISSLNGNLGNA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSQARIRSANYLANLINQAY
                     QANPEIFGTDEKFDLSSDVMKKKVSGFTGQTAGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANPETKESDDKDD"
     gene            2811..3713
                     /locus_tag="JOX41_001649"
     CDS             2811..3713
                     /locus_tag="JOX41_001649"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HAY6449394.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAFMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGAEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKVIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     ISMFKAQAFDPEVFPELLAEEVTL"
     gene            3924..5699
                     /locus_tag="JOX41_001650"
     CDS             3924..5699
                     /locus_tag="JOX41_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HAY6449395.1"
                     /translation="MLNILNPLIDQLKKKHTYFILGIAVLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIHYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(5765..7351)
                     /locus_tag="JOX41_001651"
     CDS             complement(5765..7351)
                     /locus_tag="JOX41_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HAY6449396.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQNEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHAALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQLLQETVEEIE"
     gene            7602..7826
                     /locus_tag="JOX41_001652"
     CDS             7602..7826
                     /locus_tag="JOX41_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HAY6449397.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            7968..9719
                     /locus_tag="JOX41_001653"
     CDS             7968..9719
                     /locus_tag="JOX41_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAY6449398.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAAFLQYLFRYIWRTNIWGSAARLERELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQQLEAKIEGGEA"
     gene            9719..11503
                     /locus_tag="JOX41_001654"
     CDS             9719..11503
                     /locus_tag="JOX41_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6449399.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGVYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFVAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQEFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            11838..12690
                     /locus_tag="JOX41_001655"
                     /pseudo
     CDS             11838..12690
                     /locus_tag="JOX41_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            12787..14673
                     /locus_tag="JOX41_001656"
     CDS             12787..14673
                     /locus_tag="JOX41_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAY6449400.1"
                     /translation="MGKYQELARKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGIVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAADGMIRGLTAFLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPVFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEADETDDRQKRSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMSLFPTKHAIGMVSEAGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEEEGYSLETPVIVINYMDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(14714..15616)
                     /locus_tag="JOX41_001657"
     CDS             complement(14714..15616)
                     /locus_tag="JOX41_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAY6449401.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            15846..17249
                     /locus_tag="JOX41_001658"
     CDS             15846..17249
                     /locus_tag="JOX41_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAY6449402.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPTMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            17249..18682
                     /gene="ascB"
                     /locus_tag="JOX41_001659"
     CDS             17249..18682
                     /gene="ascB"
                     /locus_tag="JOX41_001659"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAY6449403.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFPV
                     ITGKKKMFEFDENHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            18827..19753
                     /gene="trxB"
                     /locus_tag="JOX41_001660"
     CDS             18827..19753
                     /gene="trxB"
                     /locus_tag="JOX41_001660"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HAY6449404.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            19966..21693
                     /locus_tag="JOX41_001661"
     CDS             19966..21693
                     /locus_tag="JOX41_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HAY6449405.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDDEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAMRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     AIIKKMTEE"
     gene            21766..22059
                     /locus_tag="JOX41_001662"
     CDS             21766..22059
                     /locus_tag="JOX41_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAY6449406.1"
                     /translation="MPDTQKTKVEKVSQLFKMLSDPTRLKILLYLKDGEQNVTAITQA
                     VEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHVLDILNQTLKHVEHQ"
     gene            complement(22153..23013)
                     /locus_tag="JOX41_001663"
     CDS             complement(22153..23013)
                     /locus_tag="JOX41_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HAY6449407.1"
                     /translation="MSSDSTEIITFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLMQALQDALKEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            23105..23533
                     /locus_tag="JOX41_001664"
     CDS             23105..23533
                     /locus_tag="JOX41_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAY6449408.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            23695..23871
                     /locus_tag="JOX41_001665"
     CDS             23695..23871
                     /locus_tag="JOX41_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HAY6449409.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            23898..24344
                     /locus_tag="JOX41_001666"
     CDS             23898..24344
                     /locus_tag="JOX41_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HAY6449410.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
BASE COUNT         7721 a         4362 c         5191 g         7118 t
ORIGIN      
        1 gacttccttt tttgtatgga ttttttcatt tacacaaaat attttatact ctctggtttt
       61 tcacattttt acataaattt gtcttaatat cgtagatgta agcttttgaa caccatttat
      121 tcggaaaaag ggagctgtga caagattttt gtcgcagctc cctttaattc tgattaatct
      181 attagatcaa tcatctttat cgtctgattc tttggtctct ggattcgctc tagcataagc
      241 tgaagcggtg ttccagtaat ctgtatagtt ttcatcagta ccgcctacgc cgaatttaaa
      301 ggcgcttttc ttcggaccat tttttgccca aagtgactcc actgtttttc ctggcgtttg
      361 gatggatttt ttattgacag taacttttcc agctgtttgt cctgtgaacc cagatacttt
      421 tttcttcatc acatcggatg ataagtcaaa tttctcatca gtgccgaaaa tctcagggtt
      481 tgcttggtaa gcttgattga ttagattggc aagataatta gccgaacgta ttcttgcttg
      541 gctgtccatt ccagtattgt catcgtgtcc tgcccaacta ctgatagtga tagatggagt
      601 tgagacgatc agccatgaat ctcggtattc attggtagaa ccagtttttc cgacccaatc
      661 tgcatttcct agatttccgt ttaagcttga gatgacatct ttgaatggtg tagtgatttt
      721 ttcattgatc acactacgca tcatgtcatt catgatcgat gccgttgctt cggaataaat
      781 acggacagaa ttactttcat gtttataaat cacattacct gcattatctg tgatggaatc
      841 aatgatatag ccttcttcgt agactccacc atttgctaag gcctggaatc catttgtctg
      901 ttgaagcgtc gttacatcta ctgtccctaa aggagccgat tcaacgcccc aattatcatt
      961 tgctgggtag ttcatcttcg ccaagtagtg ctcgtaagcg tattgtttcg atccaccgga
     1021 attcaacaca tcttgatata agtgataagc tgggatattg ttggaccatt ccagtgactc
     1081 acggacggtt tggaaggtgt tcgacccttc attggtcgca ttgacgattt tctcaccagc
     1141 attttttcct tcttgccaag tcgttgcata atctgataca cgggattctg atccgacaag
     1201 tcccatatcg attgcaggac cgtaaacaag aaccggtttg atggatgaac cagcttgacg
     1261 ttctgtatca aaggcgtggt tattttgatt ctggctgtaa ttccgaccac ccacgaagcc
     1321 atagatacgt ccggttctgt tatccatcaa tacatttcca gtctccactt ggctaccagc
     1381 accatcatct aacatgtagc cataattttc tacgccggtt tgtaatgcag catagatatc
     1441 tttatcgatc gtcgaatgga tcgtatatcc tttgttttgg atcgtttgct gtgctttttg
     1501 ataataagct tcactgaccg atgaatctga catatcagca ttatcttttt ctgccaattg
     1561 ttgtgcaata atccttgttg cttcgttcat cacggtataa tacaagaatt ctctgtcagt
     1621 ctgttccgcg atttgttgtg ggagaaagtc ttttgtaaga tcataggctt tcgcttcttc
     1681 gtattgttct ttcgtaattt gtccttcacg gtacatactg aataaaacaa aatcttttct
     1741 ggcaagaccg gcagaaagat cttcttttag cgcgcctgta ttcgtgtatg gactatacgt
     1801 gatagggctt tgaggcaaac cagcgatata agcagcttgt ggcagagtca catcctttgc
     1861 atctacacca aagattcctc tagcagcttc ctggactcca gcaatatttt gccccttatt
     1921 attccgacca aatggtgaga cattcaaata cgtagtaatg atctcatttt ttgaaaagtg
     1981 tttttctact tgtgcagaaa gaacgatctc gtttgcttta cgtttgaatg ttgtttcatc
     2041 ggttaggatc tgttgtttga ctaattgctg tgtcaaagtg gatcctccag acgagccgat
     2101 gccagtcgct tctgaaacta gtgctcgtaa aacagcttta gggacataac cttgatgttt
     2161 atcgaagtat tcatcttctg tactgataat cgcggttttc aataaaggcg aaatcttatc
     2221 agatgaaata gtcgtccgca tcagatctgt ctggattttt gatatctctg tattatctgc
     2281 ataaacaatc tttgacgttt ccgtaatgtt tcctagttct gtctgcagtt cttttttagt
     2341 cggcaattgt gtgtcttcga caagataggc aaagtagcca gcacctattc cgatacctag
     2401 agctgcgaac aacaaaagaa gaacagtaat aaaaacagtc aatgattgaa acactctaaa
     2461 aataatctta ggaacaaacc atttttcttt ttttcttcta ttctgttttt ttcgagtatt
     2521 tttgcgtggc aaaagggtca cctcaactaa tggttttatt tcgctaatta tagcaaataa
     2581 taggacaaaa aaacagacaa ggctgttttt gacaggaatt tctttttcga atgagataaa
     2641 acgtgaggaa atgatctttt ttatgaaaga gttcttaagc ttttctttag ggaaagtttc
     2701 agttactatg gagaacaggg caaagaaaaa caaaccattt tctttgtaca tcatcttatc
     2761 aatatacagg aattgttcga aacaattgcc tttcaaggag gaatccatcc atgttattag
     2821 gctcacatgt cagcatgagc ggaaagaaaa tgctgttagg cgcggcagaa gaagcagcca
     2881 gttacggatc ttcgaccttt atgatctata caggcgctcc tcaaaatact agaagaaaag
     2941 ctatcgaaga gatgaatatt gatgccggaa aagcatttat ggcagaaaac ggactaacaa
     3001 atatcgtcgt tcatgcgcct tatatcatta atttgggaaa tacgatcaaa ccagaaatgt
     3061 ttccatttgc tgtacaattt ctgagagaag agattgtccg tgcggaagct ttaggtgcta
     3121 ctcaaatcac ccttcaccca ggcgctcatg taggagcagg ggcagaagct gggattgcta
     3181 gaattattga ggggttgaat gaagttttga caaaagaaca gacggcacag atcgctttgg
     3241 agacgatggc agggaaaggt acggaaatcg gtcgaacatt tgaggaatta gcgcaaatca
     3301 tcgatggagt aaaattgaat gaaaaattat ccgttacttt tgatacatgt catacgaatg
     3361 atgccggata taatataaaa gaagattttt caggtgtaat ggaagagttt gataaggtca
     3421 tcggattaga tcggcttaaa gtactgcata tcaatgattc taaaaatcca caaggttctc
     3481 ataaagatcg gcatgccaat atcggttttg gaacaattgg atttgacaca ttgaacaaaa
     3541 tcgtccatga tccaatgttt gacaacattt cgaaaatatt agaaacccca tatgtcggta
     3601 aagataaaaa gaaagcttac gcaccatatg gaaaagaaat ttccatgttc aaagcgcaag
     3661 cattcgatcc cgaagtgttc cctgagttat tagcagaaga agtcacactt taagttttct
     3721 acctgacagc aacaaaaaag gattgggcag tctgccttgt ccttttttgt ttaagaaaca
     3781 aaggagtgct ttttgcattc gttttcgcca tgctcctttt gccccctctt tttaaattca
     3841 gacaaacagg gtatactgat agaaaagtaa aaaacgaaaa gtttcacaaa caagtagcaa
     3901 aacgtgattg aaaggacgaa aagatgctga acattttaaa ccccttgatc gaccaactaa
     3961 aaaagaaaca tacatacttt attcttggca tagccgtatt atttacaatt attcggttgt
     4021 atttatatag taaagcaatc tatggaacag atatgtcggc gacctatgat gatcagctgc
     4081 tgattcacta tgctcaaaat attttggatg gtaaatggct aggggagtat acgactacaa
     4141 cactttccaa aggaatctcc tacagcttat ttttagtact tgcacataaa ctgcatcttt
     4201 cttatgcagt tttgttcggc atgttcagta tttttgccag tatattggtt gcactcgcgt
     4261 ttaaaccgat tgtgaagaac aagtatcttc ttttaagtat ctatttttat tttttgtttt
     4321 ctccgattag ttttacacat gaatattcca ctcgaacata tcgtaatgcc ctcgtgattc
     4381 cggctgttga gatcattatc gcttgtttat tagctattta ttaccgcaaa tacggttcta
     4441 gcagaaaatt gctgccatgg tttttagggc tttctgtcgc ttttcctttc ttttggttca
     4501 ttcgcgaaga ttctatctgg cttcttcctt ttactgtagt agctttgggt atcagtttcg
     4561 tccagatctt gctagggcaa gacttttctt tcaaagaagt aaagaagtta aaaaaacgac
     4621 tctttcttct ctcgaaacgg gaatggctga aactttcatt gtttttactt cctatagttg
     4681 gcttttccat cgtctatcag tggatcgaat ataaaaatga gacaacatac ggtattgcaa
     4741 ccatcaatga ccgttccagt ggagaatttg gacgtttgat gaaacaactg atccgaatag
     4801 atgatgaaac gaacttgaat aaagaaaaca gtgagatatg ggtctcacat gctgcactaa
     4861 ataaagcatt agccgcatct cctacattcc atactgtttc tacccgtatt gacgaattat
     4921 atacgactca cgcgtggact caaggtggaa aagtaaaaga attacccgga gatatcatct
     4981 tttgggcatt gcgagatgtg gtaagcgaat ctggttatta ccaaaacaat gcaaaagaaa
     5041 ccaatgattt ttggaaaaaa gtcaaccaag aattagaaga agcctatcac aagggaacca
     5101 tcaaaaagaa aaaagagttc tatctgatgg gatcaggaga tggaaagacg atgagtgatc
     5161 tgccaatcgt attcgatttc cttcaatcag gatacgctta tgcatggcga tataaagatt
     5221 tccatcaagg aggaaattat agtttcggaa cgcaagaaca agtcaaacag gctcaagaat
     5281 tattaaacct tccgctaatg gagaattgga tcgatagtaa tgaaccgaga acacctaatt
     5341 tccaattaac aaaatcagca aaagtcgcga atgtcatcat aaaaatttac caagttctgg
     5401 ctattcccgt gctgattgct tcaatagcag ggatattact tatgatacta ggaaccgtat
     5461 ttgcaaaagc tgatcgtgcc tattatagtt cctctttgat tgtggtcacc ggattaatac
     5521 tgacacaatt ggtttttctt ttcggtgtct catggttttg ttcttatgcg ccagaaaaaa
     5581 aggactattt tttaagtgtc tacactggtg caggcgtgcc attaacgcaa ttcatcgtag
     5641 taacaagcat gctagttttc agtaaattaa atctgaaaaa agctttatct tctaaataaa
     5701 aagacccttg gtagctagat ttttaaccta actatcaagg gtctttgtgt ggaaaaatca
     5761 gtttttattc gatttcttct accgtttcct gcaaaagctg ttcatatttt ttgtttcctt
     5821 tatataaatc accaatcgtc catgccaaca ggagaaggac aagaacaatg attacataag
     5881 cgatgtgatc agccaatgct agttgagcgg aagtggcttg ctcgccgaag aaactttcga
     5941 tctgtcctgg taatcctcgt aagttcaagt aagttagact aatcacagag aaccagccaa
     6001 gaagttttac gatgaatgaa tttttaaatc ggctacccat ctccgcttgg ctgttggtca
     6061 tcatcagtaa aggaatcatc gaaaatggca acgcaaaagc caagaacacc tgggattcat
     6121 tcattaagtt attcaaagcg gcatgttctt cgatcgttcc ttttgtactt gtaaacaaaa
     6181 cacaaatcaa tacaggaatc acagaaagca atcgtgtgac cagtcttctt agccaaatcg
     6241 ggatacgcat atggatgaat ccttccatga tgacttgacc ggtcaacgta ccagtaatag
     6301 tagagttctg gccagaagca agaagtgcta cagcaaataa agtggacaag ataccagatt
     6361 ttgctacagc aatcaaaata ccattgctca tagctgatgg atcagataaa gcttcataca
     6421 gaccaaaaaa ggaaggatct tggacagaac cggttttgaa gacagcgaca cccatgatca
     6481 atagcagtgc attgactaga aaagccattg acaactggat attagaatcc caagtagaaa
     6541 aacgtacagc ttgtgctaca tcttcttcgt tttggtgatc gatcttccga gtttgtgaaa
     6601 ctgctgaatg aagatataag ttatgcggca tgactgttgc accaataatc cctaaagctc
     6661 cagtcagcgg agtttcgccg ccgatgaccg gtgagtctga gaatgtatga ctgttaggga
     6721 taaagccagc aaataaactg tgccaatctg ggttagacaa gccaacttga tagacaaaaa
     6781 cgaataaaat gacgaaaatt aagcagacaa ccagtgcttc gatcttacga aacccgactt
     6841 ttgtcagtag taagagaacg aaaacatcta atacagtaat aaagacggca atcaccaatg
     6901 gaatatcaaa aagtaagtag agggcgattg ctgcaccaat gacttctgcg atgtctgttg
     6961 ccataatggc taattcagtc aagatccata aaatgacacc caatgtctta cttgtccgtg
     7021 ctcggattgc ttgggccaaa tccatttggg tcacgattcc taattttgct gccatatact
     7081 gtaaaagcat agcaattaga ctagacatca aaataactga catcaataaa tattggaaat
     7141 tttgtccacc agtgatcgaa gtggaccagt tacctggatc catataacca actgctacta
     7201 atgcacctgg tccagagtaa gcaagaagtg ttttaaaaaa actttttccc tttggtacat
     7261 ccactgttcc atttacttca gctaaagata aaccatttgt atgttcaata agtcgatgct
     7321 tatgaaattg tttgttggat tgattattca agaaaaaacc acctttccta tttatctacg
     7381 attacattct acacctcaga aagaaaaaat taaagaaaaa gattcggtat gcctaatttt
     7441 ttttcgtggt gtgtcttgct ggttaatgaa agaaattttg ttcttctcta aaaaaaccac
     7501 tattttttgc atgaaactaa agaatacgcc tttctttttt caataaactt tagtaaaata
     7561 aatcattgag agcaattcgg aaatagaaag gagagattta tatggtatca acaggtattg
     7621 tcgtacttat tgctattatt gctttgctaa tcggcgcagt aggtggcttt ttcctagcgc
     7681 gtaaatatat gaaagactat ttagaaaaaa atcctcccgt taatgaggac atgttgcgat
     7741 caatgatgat gtcaatgggg caaaaaccat ctgagaagaa aattcgccag atgatgcagc
     7801 aaatgaagaa ccaagggaaa aaataggttc tgacccaaag actttttgcg ggctgatttt
     7861 ttcagtccgt tttttatttc gtaatttgtt agactattca gactattcag caaaaaagac
     7921 aagcacagac aatcctatgc tcttgataaa gacaaaggag gagtaaaatg tcgattttta
     7981 gaaaattagg ttggtttttt cgtcaggaaa agaaacatta tttaattggg attttctccc
     8041 tattcgcagt ggccttggta cagttagttc ctccaaaagt gattgggatc atcattgatg
     8101 agatcgccga taagaattta tcaataaaga tcatttcctg gtggatctta ttattgatcc
     8161 ttgcagcttt cttacaatat ctttttcgtt atatctggcg gacgaatatt tggggaagtg
     8221 cagctcggtt ggagagagaa cttcggcagc agctattcaa acattttaca gaaatggaca
     8281 atctctttta ccaaaaatat cggactggag atttgatggc tcatgcaacg aatgatttga
     8341 atgcaatcca gaatgtagca ggagctggaa tcttgacctt tgcagattca gtgattacgg
     8401 gcggaacaac gatcattgcg atgattttgt ttattgattg gcgcttaaca ctgattgcgc
     8461 tgattcctct gcctttgcta gccgttactt cacgagtgct ggggtcaaaa ctccacgatg
     8521 cttttcgtga ttcgcaagaa gctttttcta gtatcaatga taagacacaa gaaagtatca
     8581 ctgggatcaa agtcattaaa acatttggac aagaaaaaga agatctcgcg gattttgaag
     8641 aaaagattga agatgcaatt attaaaaaca aacgagtcaa ttttttagac tccttatttg
     8701 atccattcat taccttgatt atcggtctgt cttatgttgc aacaattatt ttaggtggaa
     8761 agtatgtctt ggaaggcacg atctcaatcg ggcagatggt ctcatttatt agctatatcg
     8821 gtatgcttgt ttggccgatg tttgcgattg gtcgattgtt caacgtattg gaaagaggaa
     8881 atgcttctta tgatcgcgtc aatgaacttt tgcatgaaaa gacgcatatc gtggaacaac
     8941 tgggtgcagt gcagaccccg gcaaaaggcg agctgaatgt agctatttcc tcttttaact
     9001 atccgaaaga agaatcacca gcattagaac aaatcaaatt tgcgatccaa gaaggagaaa
     9061 cattaggtat tgttgggaaa actggtgcgg gaaaaacgac aatcatcaaa ttactgatgc
     9121 gtgaatacga tgattatcaa gggaaaatcc aatttggcgg acgttcgatc aaagaatatt
     9181 cattgaatgc tttattagga tcaatcggtt atgtgcctca ggatcacttc ctgttttcga
     9241 tgaccattcg agataatatc cgtttttcta atccaaaact ttcagaagaa gaagtagagc
     9301 atgcggcttc tttagcattt atcaacaatg aaatcaagga attgccaaaa ggttatgata
     9361 ccttagttgg agaacgtgga gtctctttat ctggcggaca gaaacagagg atttcgattg
     9421 ctcgagcatt gatcaaaaat cctgaattgc tgatcttaga tgatgcactt tctgcagtag
     9481 atgccaaaac agaagaagct atcttgcata atttaaaaga aataagaaaa gagaaaacaa
     9541 ccatcattgc agctcaccgt ttaagcagcg tgatgcatgc aaaagaaatc attgttgtcg
     9601 atcaagggaa aatcattgaa cgaggaaccc accacgagct gcttgcatta ggtggctggt
     9661 atgaacgaat gtgggaaaaa cagcaattag aagcgaagat agaaggaggc gaggcctgat
     9721 ggatgaaaat tatcaatcgg aatggacaaa atcgattcca cttaaagaac agaagaagat
     9781 catcaaacga ctgatgaagt tcgccaaacc ttttagaaga acgttcatcg ttgctatctt
     9841 atttgcgttt gccctgtctg tgatcaatgt cctattgcca aggatcatcc aaacttttat
     9901 ggatgatcat ctggctaaac agtcagctac gacacaagtt attttgtttt ttgctggtgt
     9961 gtacttgttt ggagtcatag tcaaaagtat catttggttt ttccaatggt atttgtattc
    10021 catggcttca ttgaagacct atcagtatgt tcgggtaaga ttatttgaaa agctgcatac
    10081 actaggtatg cgttattttg accagacacc ggcaggatcg accgtttctc gagtgacgaa
    10141 tgacacagaa acgctatttg aattttggta tgtctttttg atggtattga ctgggatctt
    10201 tgcagtcgtt tcttctttcg ttgccatgtt tcaaatcaat ggagaaattg ccttgtggac
    10261 tttggtgttc ttgccgattt taggaatcgt catctggtat taccagaaat tcagttctcg
    10321 tatttaccga aatatgcggg aaaaattaag tcagctgaac acgaaattga atgaatcgat
    10381 ttccggcatg cgtattatcc agcagtttcg ccaagaagct cgtttagcta aagaatttga
    10441 acaagtgaac aacgagtatt tagacacgcg ctatgcgatg atcaaaacga attcgattct
    10501 gttaagtcca atcatcaatt ttctctatgc attggcgatt gcgttggcgt tgactttgtt
    10561 tgggatcgat gcgttgcatt ctcccgtaga agttggactg atctatgcat ttacgaccta
    10621 tgtccaggaa ttttttaatc caatgtctca aatgatggac tttttgagca cctttacaga
    10681 tgggatggtt gccggtagtc gtattttgaa aatcatggat acagaagaat atgcaccgca
    10741 acaaaatcct ggagcagatc aagcgattac ttcaggtaag atcgagtttc gcaatgtaag
    10801 cttttcttat gatggagagc acaatgtatt gaacaatatc tcttttgtcg ctaatccggg
    10861 tgagaccgtt gcattagtgg ggcacaccgg aagcggaaaa agctcgatca tcaacgtatt
    10921 gatgcggttt tacgaatttt atgaaggcca aatcttgatt gatgatcatg acattcgaga
    10981 atatccaatg gaagagttac gtaagaaaat gggattggtc ttgcaagatg ccttcttgtt
    11041 ttatggagat attgcaggaa atatccggat gatgaatcca gctatcacag acgaacagat
    11101 tcgccatgca gctgagtttg ttcaagcaaa caagttcatc gatgaattac caaaaggata
    11161 tcactcaaaa gtgatcgaac acggtgccag ctattctagt ggacaacgac agctgatcac
    11221 ttttgcgcga acaatcgtga cagatcctaa aatactagta ttggatgaag caacagcaaa
    11281 tatcgatact gaaaccgaag gattgatcca agaaggattg gcaaaaatgc gacaaggacg
    11341 gacaacgata gcgattgccc atcggctgtc cacgattcgg gatgcagaat tgattttagt
    11401 tttagacaaa ggtcatatag tagagcgtgg gaatcatgaa acacttctag cgcaaaatgg
    11461 tttgtatgca gatatgtaca aactgcaaag cagtggtgtg taaaaagagg ttgtgacagt
    11521 agcatagtag cattttgccc taagcgctag agtgaaaata aaacagagct tcgcagattc
    11581 ttcatctgtg agcgttagtg gcgtagtcac ccgatttaaa aaagacgacg acagctagtc
    11641 aaaagcggct aataaccact aagaaagcgt tgacaaaagc gtttgctttc gataatataa
    11701 agaaaacgat acaacttgga tagtgattgc ctgatgcaag ctaaacctga tgagtctccc
    11761 atggttccat ggacggcttt ttgggttttt ctttttgttt tggatacagc cctatatatc
    11821 atggaaagga gcaaaacatg ctgattgaga aagtactgaa taacaacgtc gtaataacca
    11881 gggatgaaag aaatcaggaa atgatcgtga tgggaaaagg tttggcattc aaaaagaaag
    11941 tgggtgaccc gatttttgac tcatgcatcg acaaaaaatt tcagttgaca aatgacgggc
    12001 tttcacaaca gttccaagaa ttggcacaag cgattcctct tgagtactta gaaatttctt
    12061 gtgaaatcat tgaatataca aaagaggctc tacaagtcca gttgaatgat tctgtgtata
    12121 ttgcattgac ggatcatttg tatacggcta tcgaacgtca caaaatggga atatttgtac
    12181 caaatgtatt gctgtatgat atcaaacaac tatttcctaa agagtatgcc atcgggaaaa
    12241 aaaacagtga agaaaatctc ggataaatac cacatcaagt tatcagaaga tgaagccgga
    12301 tttatcgcat tgcatttagt caatgcacaa ggcattcaaa gccaacaaga caatacctac
    12361 ctgttcacta taacaataca ggatattcta aatatcgtcc gctattacta taagattaca
    12421 tttgatgaag attcagtcca tttttttcga ttcgtcacac acttacgttt ttttctgaca
    12481 cgcgtcctag atggagaaaa atcagaagtg ggagaagttt ctgaggaatt gtttcaggtt
    12541 attcaaaaaa aatataagga tacgtttggt tgcgttgaga aaatagcaga ctttttagcc
    12601 gagacgttca actaccagat gtccacggac gaaaaaatgt atttaacgat ccatactgcg
    12661 cgtttagtgc atgagaatcg ttgtaaataa ataaaaaaag gaggataaat taacaagaac
    12721 gtatgaaata agggtagtga cattcagttg gctaaacctt ccactaataa attggaggga
    12781 atagaaatgg gaaaatacca agaattagcg agaaaaatcg tagaaaatgt cggcgggaag
    12841 gaaaatatca atggtttgac acattgtatc acaaggcttc gtttcaaatt aaaaaacgaa
    12901 gaaaaagcaa atgatgagat cttgaaaaat atggacggta ttgtaacggt aatgcgagcg
    12961 ggagggcagt atcaagttgt catcgggaat catgtgccag tcgtgtttga agaggttata
    13021 aaagcaggaa accttacttt tgatgaggct gtttcaacag aaaaaatgag accgtttgat
    13081 atgcttattg atggaatatc gggctgtttc caaccattcc ttgctatcct agctgctgac
    13141 gggatgattc gtggactgac agcattcctt gtcttcttag gcgcgtttga ccgcggttct
    13201 ggcacatttg ttatgtttga taatatcggt gattctgtat tccaatttat gcctgttatt
    13261 atcggtttaa cagctgcccg taaatttaaa gtaaatgaat tcgtagggat gttgcttggc
    13321 gcagcattaa tgaatcctag cttgtcgctg gaagctttga gtggtgcagc agaagcacca
    13381 ctaacgacca tattttctgg cactattttt gaagcaccta tttatcaaac agtattcggc
    13441 attccctgga ttgcgcgtaa ctacgcttct tctgtcattc ccattatctt tattgtgttg
    13501 ttagctagcc aaattcagaa accaattaaa aagttagtac ctgagatgat cgcgaatttc
    13561 ttcgttccat tcttcaccgt tcttattaca atgcctttag gttttttact cgttggacca
    13621 gtattcacat tcgcaactga tattttaatg gctggatttg aaacactttt agcactttcg
    13681 ccagttattt atggagcaat cgtaggcttc ttctggcaaa ttctggtgat gtttggtctc
    13741 cattgggcaa tcgtaccaat gggattgatg caattttctg tgaatggttg gcaaaatatt
    13801 atgacacctg ttgcagtagt gtcttttgga caaactgcag cacttaccgc actctacttt
    13861 aagcttagaa atccaaaaga caaagcaatt gcaataccag ccattgtttc tggtattgtg
    13921 gggattacag agccagctat ttatgggttt acattgccac gtaaaaaaat atttattttt
    13981 acctgtgtcg gtggtgcgtt agggggcgcg tatagtgggt taatgaattt aacttcttgg
    14041 aatcaaggtg gactaggcat ctttacaatt cccaactata ttagaccaga tggtgattta
    14101 acagatgtga ttaatgtatt gattgggatc gccattgcga tggtggtatc ctttgcgctg
    14161 acttttttct tttggaagga ggaagcagat gaaacagatg atagacagaa aagatcaggt
    14221 aaagaaattg taaaaacacc gatacaagga caaatcgctc cactgaatgc agcaaaggat
    14281 gcagcttttg cacaaggaac actaggtcga ggaatcttga tctaccctga aaaaggagaa
    14341 gtacgtgccc cttttgacgg aacagtcatg tccctgtttc cgacgaaaca tgcaatcggg
    14401 atggtttctg aagcaggtct ggaattgctg attcatgtcg gattggatac tgttcagttg
    14461 gaagggaaat attttgaaag cttggtgcag caaggagaaa gagtgaaaca aggcgatctg
    14521 ttgcttcgct tcgacaaaaa gaaaatcgaa gaggaaggat acagtttaga aacacctgtg
    14581 attgtcatca attacatgga ttatttggat attttggaaa atcaagggga aacggtcggg
    14641 ccagacgatg cacttatcac cgcactgacc tgaacggtta ggtgaaagaa tggactaggc
    14701 ttaactattc tttttagtcc acttctttat tttcaaaatt gaaaggctct ttcatgatgg
    14761 ctgagctgat agggcgttta tcaaattttt gtcctacaga aattagatgg actaaattct
    14821 gttgataatt ttctgcaaaa acacaactat ataacacgtc tagaagataa caaatcgatg
    14881 tattgatcgt aaaattacca attttcgaat acagtcgttc gcgtgtcgta agtcgcaaag
    14941 cggctgtact cattgaagat agcgttgaat caccgatact ggtcaaagct aaaattggca
    15001 catgattttg tttcaatatt tctgcggtac gaaggatcac attgttttca cccgtataag
    15061 aaatcagaat cccacacata tcacttgtgc aattgtacgc ttcatagaac gattcaccaa
    15121 aagtggtgac aatcgtgaca tccattttga tgcgcttcat tttcagcatg aaatcttgag
    15181 aaatcaaagt attcgagtta ctggcgaaaa tcacgatttt ttttgcttga agcattagtt
    15241 gtttggcttt ttgcagttgg tcatgatgaa tgagagaaag tgtatcttga atcgtcatct
    15301 gttctaaaga agccatttta tttgcgatcg tcataatacc gtctgtggtg gaaaaaggaa
    15361 gattcgcatc tacgtcttga aaattccctt caagataggc tgtttcagct aaaaaagcat
    15421 tacgaaaact gacccagcca tcaaaaccca ttttttttgc tacacggatg agtgtggacg
    15481 ggtggacata acatcgctca gcaatctctt ggatggtcat ttcgccaagt gctggagaat
    15541 cgcttaagag aaactgaatc acttcatttt ctgaaggaga aaaggagatt tctttgattt
    15601 tttcacgtaa taacatgtag ataccttctt cttgtttttt tacgtaaatc ataacttttt
    15661 tgaaaatgat ttgtaaacgg atttatgtta tatagcttaa taaagacatt ttttgacaag
    15721 atatttacaa aaatccagaa gaaaacacta acttttgtaa atgttactgg aaagaaacga
    15781 atttctattg tttgttttgt ttacaaaaaa gataataaaa gtgtaaaaag taaaggagtg
    15841 agaacatggc aaaaggaatc aaaatcgcta cgattggtgg aggcagcagt tacacccccg
    15901 agttgatgga aggatttatc aaaagatatg aggaattacc gatacgagaa atctggctcg
    15961 tagatgtaga agaaggaaaa gaaaagcttg agatcgtcag tcagatgtct cagcgtatgt
    16021 gggatgcttc tccgtatgaa gtcaaaatct atgcaactct ggatcgggaa gaagcattga
    16081 aagatgcgga ttttgttacg actcagtttc gtgtcggtca attagatgca cgaatcaaag
    16141 acgagcggat ccctagttat tatgggatga ttgggcaaga aacaaatggt gctggcggga
    16201 tattcaaagc ttttcgtacc gttccagtgg ttttggcaat cgttgaagac atgaagcgtt
    16261 tatgtccaaa tgcttggctg attaatttcg cgaacccaag cgggatggtg acagaagcag
    16321 ttatcagata tggcaaatgg gataaagtga tcggattatg caatgtgcca gtaatggcga
    16381 tgatgacaga accaacaatg cttggcaaga aaaaagaaga gctgatctac aagtttgccg
    16441 gtctaaatca cttccattgg cacaaagtag cagataataa aggaaatgac cgcacggcag
    16501 aattgattga tcgtttatac gatgaagaca atggattgcc gaaaaatatc tttgacatcc
    16561 cgtttttcaa agaacaatta aaacaaatga acatgatccc ttgtggctac caccgctatt
    16621 actatcgtga agaagaaatg ctggaacatg ctttagaaga atatcaaacg attggtacaa
    16681 gagcgcagca agtgaaagaa acagaagcag agctgtttga attatacaaa gatccagaat
    16741 tggatcataa acctgaacaa ttgcaaaaac gaggtggtgc ttattattca gatgctgcct
    16801 gtgaaacgat tgcttcgatc tatggaaata aagaaacaca gatcgtggta tctacaaaga
    16861 atgatggagc tgttcctgat ctgccggcag attgtgtagt agaagtcact gcctatgttg
    16921 gcgcacaagg cgcacgaaat gtagcgtttg gttcccttcc tgctgctgaa agaggctggt
    16981 tgcaagtaat gaagaatatg gaattgctga cgatcgaagc agccgtgact ggtgattatg
    17041 gaacagcttt gcaagcgttt acgatcaatc cgcttatacg atcaggaaag acagcaaaac
    17101 ggatcatgga tgagttgttt attgcacatc agcagtattt accgcaattc aaggaaacaa
    17161 tcagccggtt aaaagcagaa ggaatcgaag tccaagatga actggcaaga gaattatcaa
    17221 gcaatacaca tgtaatggag gaagtatgat gggattcaga aaagattttt tatggggcgg
    17281 agctacagca gccaatcaat gcgagggcgg ttatgatgaa ggcggacgtg ggttagcgaa
    17341 cgtagatgtt gtgccaatcg gagaagaccg ttttcctgtc attactggaa aaaagaaaat
    17401 gtttgaattt gatgaaaatc atttttatcc agcaaaaatt gcgatcgata tgtatcatca
    17461 ttataaggaa gatattgctt tatttgcaga aatggggttc aagacttatc ggatgtccat
    17521 tgcttggagt cgtatttttc caatgggcga tgaaaaagag ccaaatgaat ctgggttgaa
    17581 attttatgag gatgtcttta aagaatgtca aaagtacggg atcgagccgc ttgtgacgat
    17641 tacacatttt gattgtccga tgcatttgat caaagaatat ggtgcgtggc gttccagaga
    17701 actcgttggt ttttatgaaa atctgtgccg agtcatcttc aatcgctata aaggacttgt
    17761 caaatattgg ttgacattca atgagatcaa tatgatcctt catgcaccat tcatgggcgc
    17821 agggctgtat tttgaagaag gagaaaatga agaacaaatc aaatatcaag cggcacatca
    17881 tgagttggtt gcaagtgcca tcgcaacgaa gatcgctcat gaagtagatc cggagaacaa
    17941 agtaggctgt atgctggcag caggagcata ttatccatac acttgcaatc ctgaagatgt
    18001 ttgggcttct agaaagtcag atcgagaaaa ttatttcttc attgatgtcc agtcacgagg
    18061 agaatatccc gcttatgcat tgaaagaaat ggaacgaaat ggcattcaga tcaaaatgga
    18121 acctggggat gccgcattgc tgaaagaaca tactgttgat tttatctcct tttcttatta
    18181 ttcttctcga gtttcgacta ctgacaacga actcttggaa cagactgcag gaaatatctt
    18241 tgcttctgtc aaaaatccat atctggaagc aagtgaatgg ggttggcaaa ttgatccatt
    18301 aggcttgaga ataacgatga atgatattta tgatcgttat caaaaaccac tatttattgt
    18361 agaaaacggc ttaggtgcag tcgatacgcc cgatgagaat ggttatgtgg aagatgatta
    18421 tcgaatcgac tatctggcag cacatatcca ggcaatgaaa gatgcagtag aattagatgg
    18481 agtcgatcta ttaggctata cgacttgggg atgtattgat ttagtatcag ctggtacagg
    18541 tgagatgaag aaaaggtacg gattcattta tgtcgatcgt gacaacgaag gaaatggcac
    18601 attagcccgt tcgaagaaga aatcattcaa ctggtataaa aaagtaattg attcaaatgg
    18661 agaaaatctt tcgaacgatt gatcaatgat ttataaaagt ctattgtttt tcagcggatt
    18721 tttcgagtat aataaagcta ttcgagaaac gcaagcagaa caatagactt tttttcgcat
    18781 tggctgtaaa gtatgcttac ttgattaagt aaaggagaat ctacatatgt atgatgtaat
    18841 cgttattggc gcagggcctg ctgggatgac tgctgcttta tatgcttcac gttcaaactt
    18901 atccgtattg atgatcgaac aaggcgctcc tggcggccaa atgaacaata cggcagaaat
    18961 cgaaaactat cctggtttcg attcaatcat gggtcctgat ctagcttata agatgtatga
    19021 aggtgtttca agatttggga cagaaaatgc ttatggaatc gtgcaagata tcaaggatca
    19081 cggcagccac aaagaagtta tttgtgaaga taaaacttac gaaggaaaaa cagtcattat
    19141 cgcaacaggc tgtatccacc gtaaattagg cgtacctggc gaggaagaat ttgctggacg
    19201 tggcgtttct tactgtgcag tttgtgatgg tgcatttttc cgtaacaaac gtctagtagt
    19261 gatcggagga ggagactcag cagtagaaga agccatctat ttgacacaat ttgcttctga
    19321 agtagtcatc gtccaccgta gagatgaatt acgtgcacaa aagatcatcc aagaccgtgc
    19381 atttgcgaat gaaaaaattt cctttatgtg ggatacagtc gttgacgaaa tcgttggaaa
    19441 tgaaatggta gtgacaggtg tgaaagcacg taatgtcaaa actggcaatg agtttgattt
    19501 ggcagcagac ggagtattca tctatgtagg attggatcca ttaactgcac catttagaga
    19561 agctgggttg acgaacgaag ccggctggat tccaacagac aacgaaatga agacgaatat
    19621 accaggcgtt tttgccatcg gagatgttcg tgaaaaagat ttgcgacaaa tcactactgc
    19681 tgttggtgat ggtgggattg ctggacaaca agtgtataaa tacttggaat ctttagaaga
    19741 aacaactgca taagtttaaa aagagtgaaa gaacggtttc aattgttctt ttactctttt
    19801 ttttgcgtga aatctactga atccgattta tgcgaatact tgtaaccgtg cttgataaaa
    19861 gaatcttttc ttgatttaag cgttttttgg tcctcatact ttcatatcta ataagtgaat
    19921 gctatactta ttaagaacca tatttcagaa agaggtgtta ttttcatgtc ttgggaacaa
    19981 gtgtatgaac aatgggtaca tgaagaaaat ttagaagaaa acttaaaaaa acaattaaat
    20041 gatctgggtg aagatcctga aaaacttgaa gatgcttttt atgcaccgtt ggaattcggt
    20101 actgcaggca tgcggggaat cttaggacct gggatcaatc gaatgaacat ctatacggta
    20161 agacaagcaa cagaaggact tgcacgtttc atggatacac aaggtgaaga aacaaaacgc
    20221 cgaggtgtcg ctatcgctta tgactcacgc catcaatcac cagaatttgc catggaagca
    20281 gccaaaacat tagcacatca caatatccct tcttatgtat tcgaaagttt acgtccaaca
    20341 ccagagcttt cttttgcagt ccgtcatttg aagacgtttg cgggaatcat ggtaactgca
    20401 tcccacaatc cagcagctta caacggatat aaagtctacg gagaagatgg gggacaaatg
    20461 cctcctgcag acgcagatgc attgacgaaa tatgtccgtg aagtcagcaa tccgttaaaa
    20521 gttgaagtat tatctgacga cgaagctgaa catagcggat tgatcacgat catcggagaa
    20581 gaagtggatg ccgcttatct agaagaaatc aaagcagtaa cgattgatca tgaattggtg
    20641 gaaacaatgg gtaaagattt gaagcttgtg tacacaccac ttcacggaac aggaaaaatg
    20701 ttgggcgaac gtgcgttgaa acaagctgga ttcgaacaat tcgtactagt tccagaacaa
    20761 gctgtcgcag acccggattt cactacagtc aaatcaccga atccagaaga acactctgct
    20821 ttcgagtatg cgatgcgact tggcgagaaa gaaggcgctg acttactgat tgcaacggat
    20881 cctgatgcag accgtttagg cgcagccgtt cgtttgccaa atggctccta tgaagtattg
    20941 acaggaaacc aaatcggagc cctgtttgct caatatattt tggaagcaca ccaatcgcga
    21001 ggcactttac ctgaaaatgc agcggtattg aaatcaatcg tttctagcga attgcctaca
    21061 gcaattgcgg aacactatgg ggctaccatg ttcaatgtat tgacaggatt caaattcatt
    21121 gctgaaaaaa ttcaacaatt tgaagaagat cattcccata cttttatgtt cggattcgaa
    21181 gaaagttacg gttatttagt taaacctttc gttcgcgaca aagacgcgat tcaagcattg
    21241 ctcttattag cagaagtagc agcttactat aaaaaacaag gcaaaacatt gtatgacggc
    21301 ttgcaaacga tttttgaaac atatggctac tacgcagaaa aaacgatttc tgtgacaatg
    21361 agcggacaag aaggctctgc aaaaatctct gctttgatgg aaaaattccg tgaagaagca
    21421 ccgacagaat ttgccggagc aaaagtcatc caaacagaag acttcaaaga gttgacgaga
    21481 acagaccgtg aaggaaacgt agaaaaacta acgacaccgc catctgacgt attgaagtat
    21541 acgctggaag aaaatggctg gatcgctatc cgtccttcag gaactgagcc gaaaatcaaa
    21601 ttttatatcg gtgtaaaagg aaactcttca gaagacgcag ctgaaaaagt agccgcttat
    21661 gaagcgatta tcaaaaaaat gacagaagaa taaaaaaact tgagactgat ggaaaaagtg
    21721 gtaaacttta gaagtcagtc ttttttcaag ttggaggtga atggattgcc agacacgcaa
    21781 aaaacaaaag tagagaaagt cagccaacta ttcaaaatgt tgagtgaccc cactcgtctc
    21841 aaaattctgc tgtatctgaa agacggggaa caaaatgtga cagcaatcac ccaagcagta
    21901 gaaatggaac aatctgctgt atcgcatcaa ctgcgtttat taagagaaaa ccatgtcgtc
    21961 aagtcccatc gtgagggaaa agcgattttg tatagtcttg atgattctca cgtactggat
    22021 attttgaacc agacgctcaa acatgtggaa catcaataac gataggtgca aatagagaca
    22081 aactggactg tatcaacgaa tcttcttcgc tgacacagtc cagttttttt aagaaaaaga
    22141 caagaaaaac tgttagtctg tttcttcggt ggtttcagtt ccataataac tatgatcttc
    22201 taggtctaaa gcattcaaaa taagtgaagc tgtttcttcg atagataaag aagcgacatt
    22261 gattactacg cagcccaatt tttcataaag atcattcgca aaatcgagtt cagctcgtat
    22321 tttttcgata tcggaataag cagtatcagg atttaatccg taagagcgca tccgttcttt
    22381 acggatattg tttaaaatat ctgggttatt cgtcagtccc acgatttttt taggatcgat
    22441 ctcccaaagc tgtttgggaa tatgtgcttg tgggatcaaa ggtagattgg caacctttaa
    22501 atttttgtta gctaaaaaca agctcaaagg cgttttggaa gttctggata cgcctagcaa
    22561 aacgacatct gcttctagaa acccacgagg atctttcccg tcatcgtatt ttacagcaaa
    22621 ttccattgct ttgatccgtt tgaaatagtt ctcattcaat aaatgaaggg cgccaggttg
    22681 ccgaatgggc ttgataccag ttaagcgctc gatttctgat atcggcggag tcatcacatc
    22741 aaaactaaat aattgatgtt cttcacaaaa agaacgcgtc atctcgatca attcttgatt
    22801 gatcaatgtg tgtaggacaa gggctttttc ttttagtgca tcttgcagtg cctgcatcaa
    22861 tgttttctca tctgtcacaa atgttctgcg gaataaattg aactcaacgg taggatattg
    22921 ggccatagtg gcttgcgcta attttgtcgc agtttctcca gcagagtcag agatgacaaa
    22981 aaaagtaatg atttctgtag aatcggaaga catggataaa acctcacttg catttttttt
    23041 atgtttatta taccatactc tagaatgtgt acttcgtaat cattttgatt tggaggaata
    23101 agtcatgaaa aaacagacat tgattgaaca atcactagaa acattgaaaa ataacggttt
    23161 taaatatact aaaaaaagag aagcattgtt aacttattta gtgaagcgca atcgctacgt
    23221 atccgctaaa gaagtttttg actatatgaa tcaggaattc aaaggagtaa gttacgatac
    23281 gatttatcga aatctccatg attttgcaga aatcgattta ctggaagaaa ccgatttaaa
    23341 tggagagatg aagtttcgtt ttcattgctg tcaaggggaa atcggccatc accatcactt
    23401 tatctgtacg gtgtgcggaa caacgaaaga aatccatatg tgtccaatga attatttcga
    23461 agaacagctc ggtggatgta cgatcgaagg gcatagattc gagattttcg gaagatgtga
    23521 aaattgtcaa taaggattta aataaaataa catttgataa ttttaaaaaa aagcaagatt
    23581 tccttgacgg tcaaaacagc attagatata atatttacag gacagtcttg ttttttgaga
    23641 tatatttcaa taacaattac ggttactttt taagctcgga gggagggaat taacatgtca
    23701 aaaacagtcg ttcgcaaaaa cgaatcactt gacgatgctc ttcgtcgctt caaacgttcc
    23761 gtgtcaaaag cgggtacttt acaagaatct cgtaaacgtg aattctacga aaaaccaagt
    23821 gtaagacgca agaaaaaatc tgaagcagct agaaaacgca aaaaattcta gttctgtgat
    23881 gaattggagt tggtagtgtg tcactactaa gtagattaaa cgatgacatg aaaacagcga
    23941 tgaaagcgaa agataaggaa tctttacaag tcatccgaat gatcaagtca tctatacaaa
    24001 acgagcagat taaagaaggt cacgacttga cagaagaaga agaattaacg gtgttgtctc
    24061 gcgaaatgaa acagcgacgt gattctttgc atgagtttga agaagcagga cgtgacgatt
    24121 tagctgaaaa agtaaaaagt gaaattgtga tagtcgaaaa atacatgccg gaacaacttt
    24181 ccgacgaaga aattcgacaa cttgttcaag aagcaatcac acaaactggt gcttcatcaa
    24241 tgaaagaatt tggcaaagtc atgggtgcga tcatgcctaa agtcaaagga aaagcagatg
    24301 gaaaccaagt aaatgccatt gtgaaagaac tattacaatc ttaattttat catttaaagg
    24361 ctcttcgtca atgagtgttg gtgaagaaat tc
//
LOCUS       DADLIO010000038        24258 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.038, whole genome shotgun sequence.
ACCESSION   DADLIO010000038 DADLIO010000000
VERSION     DADLIO010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24258
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.038"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(45..1340)
                     /gene="purB"
                     /locus_tag="JOX41_001667"
     CDS             complement(45..1340)
                     /gene="purB"
                     /locus_tag="JOX41_001667"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HAY6449411.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(1353..2486)
                     /gene="purK"
                     /locus_tag="JOX41_001668"
     CDS             complement(1353..2486)
                     /gene="purK"
                     /locus_tag="JOX41_001668"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HAY6449412.1"
                     /translation="MINLVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVS
                     DCPAAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTD
                     LLAITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKG
                     QYVLKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHN
                     NILHETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRP
                     HNSGHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENK
                     PDWQFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            complement(2470..2958)
                     /gene="purE"
                     /locus_tag="JOX41_001669"
     CDS             complement(2470..2958)
                     /gene="purE"
                     /locus_tag="JOX41_001669"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HAY6449413.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            complement(3374..4681)
                     /locus_tag="JOX41_001670"
     CDS             complement(3374..4681)
                     /locus_tag="JOX41_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HAY6449414.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            complement(4684..5265)
                     /locus_tag="JOX41_001671"
     CDS             complement(4684..5265)
                     /locus_tag="JOX41_001671"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HAY6449415.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     regulatory      complement(5381..5478)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(5837..7129)
                     /locus_tag="JOX41_001672"
     CDS             complement(5837..7129)
                     /locus_tag="JOX41_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAY6449416.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     gene            complement(7126..7749)
                     /locus_tag="JOX41_001673"
     CDS             complement(7126..7749)
                     /locus_tag="JOX41_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449417.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            complement(7752..8588)
                     /locus_tag="JOX41_001674"
     CDS             complement(7752..8588)
                     /locus_tag="JOX41_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAY6449418.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            complement(8605..9492)
                     /locus_tag="JOX41_001675"
     CDS             complement(8605..9492)
                     /locus_tag="JOX41_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAY6449419.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            complement(9508..10791)
                     /locus_tag="JOX41_001676"
     CDS             complement(9508..10791)
                     /locus_tag="JOX41_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAY6449420.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            complement(11474..12157)
                     /locus_tag="JOX41_001677"
     CDS             complement(11474..12157)
                     /locus_tag="JOX41_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAY6449421.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(12175..12792)
                     /locus_tag="JOX41_001678"
     CDS             complement(12175..12792)
                     /locus_tag="JOX41_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HAY6449422.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(12802..13626)
                     /locus_tag="JOX41_001679"
     CDS             complement(12802..13626)
                     /locus_tag="JOX41_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HAY6449423.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(13619..14179)
                     /locus_tag="JOX41_001680"
     CDS             complement(13619..14179)
                     /locus_tag="JOX41_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449424.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            14353..15309
                     /locus_tag="JOX41_001681"
     CDS             14353..15309
                     /locus_tag="JOX41_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAY6449425.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(15614..16570)
                     /locus_tag="JOX41_001682"
     CDS             complement(15614..16570)
                     /locus_tag="JOX41_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HAY6449426.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            16674..17276
                     /locus_tag="JOX41_001683"
     CDS             16674..17276
                     /locus_tag="JOX41_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAY6449427.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(17364..18863)
                     /locus_tag="JOX41_001684"
     CDS             complement(17364..18863)
                     /locus_tag="JOX41_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HAY6449428.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(18879..19403)
                     /locus_tag="JOX41_001685"
     CDS             complement(18879..19403)
                     /locus_tag="JOX41_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449429.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            19701..20450
                     /locus_tag="JOX41_001686"
     CDS             19701..20450
                     /locus_tag="JOX41_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HAY6449430.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            20441..21226
                     /locus_tag="JOX41_001687"
     CDS             20441..21226
                     /locus_tag="JOX41_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAY6449431.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            21195..21911
                     /locus_tag="JOX41_001688"
     CDS             21195..21911
                     /locus_tag="JOX41_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAY6449432.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(22013..23032)
                     /locus_tag="JOX41_001689"
     CDS             complement(22013..23032)
                     /locus_tag="JOX41_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HAY6449433.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(23051..24109)
                     /locus_tag="JOX41_001690"
     CDS             complement(23051..24109)
                     /locus_tag="JOX41_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014372913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HAY6449434.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQSMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
BASE COUNT         7189 a         5222 c         4224 g         7623 t
ORIGIN      
        1 tttttgctat tctattttaa ttgaattttg caactcactc ttctttattc caaacctact
       61 cgtttgaata tcacgtcaac gtttttcaaa tgatgatgat aatcaaaggc atcgtctatt
      121 tcttctttag ataataccga tgtgatggtt ggatcttctt ctaacagcgg gcggaactgc
      181 acttggttgt cccaagcgta cgcagttttt ggctgaacaa gatcataagc ttcttctctt
      241 gtcattccct tatcgatcaa tttcagcata acgcgctggc tataaatcaa accaaatgtt
      301 gcagacatat tccgcttcat gttttcagga aagaccgtta gatttttaac gatattgcca
      361 aaacgattta acatgtaatt caataaaatc gtggtatcag gcaagatgat tcgttctgct
      421 gaagaatgag aaatatctct ttcatgccat aatgtgacat tttcataggc agtgaccatg
      481 tgtccgcgca ccactctggc tagaccagcc atattttctg aaccgatcgg attccttttg
      541 tgcggcatag cagaagaacc tttttgacct ttcgcaaaaa attcttctac ttcacgtgtt
      601 tcggattttt gcaatccgcg tatctctgtt gcaaaacgtt caatacttgt agcaataagc
      661 gccatcgctg agaaatattc agcatgtaga tcccgaggga gaacttgagt agagatttct
      721 tgtggacgga tccccaattg tttacataca tactcttcaa taaatggcgg gatatttgcg
      781 aacgttccca ctgctcctga gatttttcct gcttctactc cttttgccgc atgttcaaat
      841 cgttcgatgt tccgtttcat ttctgaatac catgtggcaa gtttcaatcc aaaagtagtt
      901 ggttcagcat ggacaccgtg tgtccgaccc atcatcactg tatatttgtg ttcttttgct
      961 ttttcgccaa tgatttccgt aaaacgtttc aagtcttccc gtaaaatatc atttgcttgc
     1021 ttgatgagat agccataagc agtatctacg acatccgtac ttgttagacc ataatggacc
     1081 cattttcttt cttctcccaa tgtttcagaa accgctcgtg taaacgcaac gacatcatgg
     1141 cgtgttaatt tttcgatttc caagatccga tcgatatcaa atgatgcatg ctcacgaatt
     1201 tttttcacat cttcttgcgg gatttcacca agttctgccc aagcttcatc tgctaaaatc
     1261 tcgacttcga gccacgcacg gtatttgttc tcttccgtcc agatattccc catttcaggg
     1321 cgtgtataac gttctaacat gttttttctc ctctaatccc aaatattcgt ttgtttgatt
     1381 tcttccagcg tttgctggat gtcttctgtc aagatagtga tatgtcccat cttgcgacct
     1441 ttttttgctt gtttttttcc atagaaatgg aattgccagt ctggcttatt ctcaatcaag
     1501 cgatagcttt ccagcagttg ttctcccaaa acattgacca ttactgcatt gcttatcaaa
     1561 cgtacttttt ctcctaatgg ccaaccacaa atacctcgaa tatgggcatc gaactgactc
     1621 atagaacaag cttcaataga ataatgtcca gaattgtgag gacgaggagc taattcattc
     1681 acatatagcc cgcctgtttt tgttaaaaac atttctaccc ctaaaacacc tgaaaggctc
     1741 actgcttctg caatcacacg ggcaatacgc tcagcctcct cgatcacatc ctgatcaatc
     1801 gcggctggag caatcgtttc atgaagaata ttgttgtggt ggatgttttc cacgaccgga
     1861 aaagtcgtga aatctccttg accatttcct gccaccatga tcgaaatctc tttttcaaac
     1921 gggatccatg cttctaaaac acaggttcct tctcttaaaa ggtccatggc aggagctaga
     1981 tccgcccgac ttttcaaaac atactgcccc ttgccatcat agccgcctcg agtggttttc
     2041 aaaacacaag gatagccgat cccgtcaatc gcatcttgga tatccgtcgg actgacgatc
     2101 gttgcataag gagcaatcac gatgttattc gtttccaaaa aagatttttc taacaggcgg
     2161 tcttgcgtaa tcgcaagcaa gtctgtccct tgaggaataa atgacatggg taaaatcgca
     2221 tttaacgcct ctacactgac gttttcgaat tcataggtaa tgacatctgt tcttctggca
     2281 agctctttca gcgcaaaggt gtcatcatag acactttcaa tgtgccaatc tgcaacttgt
     2341 gcggctggac aatcgctcac aggatccagc acacctactt taaagcccat ttcttttgca
     2401 ctaatcgcca tcatacgacc taattgaccg ccaccgacga tcccgatcgt tgaaccaggc
     2461 aacaaaggtt taaccaagtt gatcactact ttctataaca gttttagcca acattgaacg
     2521 tctttcagcc aatttagcct ccaattctaa atcatacatg gaaagcatct gtatcgcaag
     2581 tagtccagca ttaattgctc ccgcttttcc gattgctgta gtagctacag gtactcctcc
     2641 aggcatttgg acaatcgaaa gaagcgaatc caaaccattt aatgttcgtg attggaccgg
     2701 tacaccgata accggcaaag ttgtttttga tgcgaccata cccggcagat gcgcggctcc
     2761 ccctgctcct gcaataatga ttttgattcc tttttttcga gcgttttgtg catattcaaa
     2821 catcaaatct ggggttcgat gagcagaaac gacctttttt tcataagaca caccgaattc
     2881 atccaatatt tgacatgctt ctttcattgt ttcccaatct gaagtactcc ccataatcac
     2941 agagattttt gctgtcattg tttttcctcc cagtttttct acattcatat tttaacaatc
     3001 actttttttg atgtcaaaga aatttcgaat gttaacaaag aaaaacattt tattgttcgt
     3061 gtttattaaa gataaaaaaa aggaatgtga caaaagttag gtcacattcc tttttatgga
     3121 taaacggtgt tctcctgcca actcctcggt cacaaggaac aatattcaac aaacatgaga
     3181 agcttttttt tgaaattgtt ccttgtgact cggagatgaa cggcaggctc acgacctctt
     3241 ccttcaacgg tgttcaatca gctgaccctc ggtattagct caaacaaacg gcaaaatacg
     3301 aggaactatt tttccgtttg tttctctaac aatcaggtca aaacgctgat ttcacaacct
     3361 ttcttttgct ctattacttc ttgaaggctt cttccaatat ttcttcatct tttttcaatc
     3421 cattaaagat caaattcaat atgatagccg taatgctact cattacgatg ccatttccag
     3481 tgaacatttg caatgtttgc ggcatttgac tgaataatgt cggcgtaaca ttgaaaccca
     3541 gcccaaatcc aacagaaaca gcaacaatca atagattttt atcattgctg aaatcaactt
     3601 ccaacagcat acggattcct tggactgcca ccatcccgaa catgactaac attcctccac
     3661 caagtaccgg ctcagggatg atttgtgcta acgcaccgat tttagggaat aatcctaaaa
     3721 caatcaagaa gaatgcagag aaatagatgg gttttcttgt tttgattccc gaaagttgaa
     3781 ccaatccgac attttgagaa aagccagtat aagggaatgt attgaaaata ccgcctaaga
     3841 taacggcaag tccttctgca cgatatccct ttttcaattc ttcttctcca acatttttcc
     3901 cagtaatgtc accaagtgca aaatatacac ctgttgattc taccatgctg accatggaaa
     3961 tgatgatcat tagtaaaatc gaccatacgt cgaaagttgg tttaccaaaa taaaagggtt
     4021 gtggaacatg gaacaacggc gcatctccaa tcgcgctcag atcaatcatt cccatgaaag
     4081 cagctaagat gcttcctccg actaaaccaa tcaataccgc gattgaacga atgaaccctt
     4141 ttgccagcat ttgcacgcct acaattagga gaatcgtcac aaatgcaagt agcagatttg
     4201 ttttgtcacc aaaatcagct gctgttgcat tacctccacc cattttctcg attgctacag
     4261 gaatcaaagt caaaccaata acggtgataa ccgttcctgt tactatagga gggaatagtt
     4321 ttttaatttt agaaaagaca ccagaaacta acacaacaaa gatcccagaa gcgataatag
     4381 atccgtagat agctcctact ccttcattgg ttccgatcaa gatcagtgga gctactgctt
     4441 ggatcgcaca tcctaaaacg acaggcaagc caattccgaa aaatcggtta actgtcaatt
     4501 gcaataatgt cgctaatcca cacataaaga tatcaattga aatcaaataa gtcatctgtt
     4561 cttgattaaa gcctagtcct gtaccgatca aaagaggcac cgctactgct cctgcataca
     4621 tcgctagcag atgctgcagc cctaaaaccg cagcttttcc attttgtgtt tctttttcca
     4681 cgattatgcg tcctcctcaa gaaactcaac ttgtccattc gtcaaggaag caatacgcgc
     4741 aagagaaacg actctcaatc ccatttcttc aagtaactga cgtccatctt ggaaagactt
     4801 ttcgatgacg atcccgattc cttctacttg cgctccagct tgctggcata attcgatcaa
     4861 tccttttgcc gcttgtccgt ttgccaagaa atcgtcgata atcaatactt tgtcttctga
     4921 agataaaaat ttacgagaaa tagaaatcgt acttgtcact tgtttcgtaa aagaataaac
     4981 agaagctgtc aataattctt catccatcgt caaacttttt gcttttctag cgaagatcat
     5041 tggaacatct aattctcttg cagcaaataa agctggtgcg atcccagaag cttcaatggt
     5101 cacaactttc gtgattcctt gttctttaaa tacttctgca aaccgttttc ccatttgttc
     5161 catcaataca gggtctactt ggtgagtgac gaagctgtcg acttttaata cgccctcgcc
     5221 taatatacgt ccgtcttttt gaatacgttc aactaattct ttcactttat ttgctccttt
     5281 atcatttatt aataccgaaa taaccgcttt tgtgcaaaaa cctactatgt ttctgttaaa
     5341 gaaaaacacc ctccacttta tcataagaaa agaagggtga aatagccaat cttttactta
     5401 tagtccagca tttacggtac tggctagaaa ctgtcatcca tattatgacg atatataagt
     5461 aggtatgtaa aactaataat agtgtaaatt cattttcttg caactgtttt gcacgtgaag
     5521 gcagtttgcc atatttgaat aaaaaatgtt gtttcaaata ttgaaaacag tctaacacta
     5581 ctttctgaaa ctgacaacgt ggtttactta tttttttgta aaatctaatg atttttaatg
     5641 cattattcct ttttgttcgg gtttaaatag ttatttttat tttctcctat ctaaaaaagc
     5701 agcccacata aaaagaaggc atgacaaaaa gcatgtcata gccccttttt ccgaataaat
     5761 agtgttcaaa agacagccta tcggcaataa ggcaagattt tataaactac gggaagtaat
     5821 ttccgtaaat ctattcttat tcttttaagc tgacaagctc gtcaatcact actgcttttc
     5881 ctgaagcaat agaatgattt gctgcgattc ctgtcaaaat cgacaaaata ccatctacgt
     5941 gagttgctgc ccgattccac ggatcttctt ctttttcttc accaaataga tcatctaata
     6001 aacgcggatc tcctccgcca tgtccgcccg cttcttgttc gacgattacc tcatatggct
     6061 caccgaacat cggatagaca tggatggact gaagaacggc tgctccttca tcctttttat
     6121 ctccacctgc attgatgtaa gacttttcga tcactttcat ttcgatccgt cctttgctgc
     6181 cattgaaaga aacattgaat ccttcccacg gcatatacgc gtttagcgaa tacgtcaaaa
     6241 tcgcaccagt ttcatatttg accgttacgc ctagtgtatc ttcaatagag atatcatcgg
     6301 aaaatacact gcggtcacga atatatccac tgtctttttc tgcttctaaa tacatttctc
     6361 gcaattcctc attggctgac aggtctatag caaatggatc agctttagct agttcgcttc
     6421 catagcatcg actgtaaaat atttctactc cgcgtttctc cgcattatgc atcccataaa
     6481 agtttaatcc accgaatgca aatacctttt ggggacggct gttcaaccaa aaattcacta
     6541 gatcaaaatg atgggtagat ttatgaacaa gaagcccgcc gctattgtgc ttatttcgat
     6601 gccatcttct gaaataatct gccccgtgtt gcgtatttaa cagccattcg aagtggatag
     6661 aaaacacatc accaatcaca tcactttcta tcagttcctt tatcttcgtg tgatacggtg
     6721 cataacgata attaaaagtg actcgcaggc ttcttcccgt ctgtttttgg accgttatta
     6781 tttcttgagc tttttcctca tcgatagtca gaggtttttc gcaaataaca tcatatcctt
     6841 ttttcattgc acgaatgata taatcatgat gcgttcgatc tactgacgta ataatgactt
     6901 cagccggccg tacgtcatcc agtagttgct caaattgtga tggcatacat gtctttactt
     6961 ttttctgtcc atacttgttc acaagtatcc gatttgcata atccatcctt gtttgagata
     7021 catcacaaaa accgactagt tcacaagttt gatgatacgt agaggcaatt gcctcataaa
     7081 aaaaacgcgc tctcccacca agtccgactt gtacatattt tttcttcatt taaagtcatt
     7141 ctccttttct tttaagcaaa atactgtgac aaatggcagc cctggataca gtaatgcagt
     7201 gagtaaaaaa tcatgctgta tacaccagaa cagtccatac aaaaggcata aataccacag
     7261 aaaccccttg acgttttttg acaacagcca gatattcctt ttgatcaaat aaacaagact
     7321 atctgcttta tcttctttgc agatatcaat tagcgtacta aaaaaactat gggatacaaa
     7381 aagcaacaga cacaatagaa aaggaatcag ataccaagct ccaatctttc ccactaataa
     7441 ataccaatca actgcaaaaa taatgacaaa cagctgaaac aacgtaatga tgaaacacat
     7501 ccgtttgatt tttcctttcc tccaacatac ctttttttct gccaagtaat ggacagatag
     7561 ataataagaa ggatacatca tcaaaaaata aatcagatag acaacacgag cagacagcac
     7621 taatcctaaa gtgaacaaac atcctagaac taaagcgaaa agagcattac tgataagact
     7681 ggttaaaaaa atccgacaga catagtagtt gagcttgtaa agaaacatct cttctattgg
     7741 ctttttcata ttcagccctt cagaccgctt gtactgatcc cctggacaag atatttattg
     7801 aagaataaga aaatcagaaa aaccggtagc agcgacaacg tagacatcgc aaacatactc
     7861 gcgtaagtcg tactagatcc agcgtctgca aataatttga tggcaatcga taccgtgtaa
     7921 gatctcggct tgtttaaata aatcaatggt cccatgaagt cgtcccattt ccaataaaac
     7981 tggatgatga tcgtcgtgat gatcgaaggt ttcagcaaag gaaaaataat tttggtaaag
     8041 acactatact tgctgcatcc gtcaataatc gctgattcat ctaactcttt ggggatgctg
     8101 accatgaatt gcatgatctg gtaaatgaaa aatgcttgtc caaaaaaatg tggtaaaatc
     8161 agcggcacat acgtcccaac caaattcagc cgattgtaaa taataaactg cggaatcaaa
     8221 atcacttgtg caggaatcat catcgttact aacatgacga cgaaccagaa tctttttcct
     8281 ttgaaatcga ttctcgataa tgcgtaagca atacaagtcg agctcagaac tgtccctatc
     8341 gtcgaaactg cagagatgac aaacgaattc ctaaagaaag taaaaaatga aattccagca
     8401 aaccccgccc atccttttgc gtaattttcc cattgaaaag tctctggaat caaattcagc
     8461 gaaccactca taatctcttg atccgtttta aaagaacctg cgatcatcca taagaccgga
     8521 taaatcatga ctagacctaa tagcaaaata aaaccgtatt gaaaccattt cgttactgta
     8581 ttattcattt cttcctcctc tcattcacac aacgacccat ttttttgatg atttgaaaat
     8641 cagaaaggtg acagctccca taatcaacag catgatccac gaaatagcac tagcataccc
     8701 catagaatta aaagaaaaag cttggttata cacataaaga gcataaaagt tcgtggcatc
     8761 attcggacca ccttgggtaa tgataaatgc ctgcgtaaaa gtcataaacg ccgcgattgt
     8821 ctgcataacc aagttataca aaatgatcgg cgaaagaaga ggtaacgtga tcttgtaaaa
     8881 cgtctgccat ttgttcgctc catcgatctc tgccgcttca taatacgagc ctgggatctc
     8941 tttgatacct gcagcaaaga tgatcattgc cgaaccgaat tgccaagcag acatcaaaac
     9001 aagagggatc atgaccagtt tttgatcgct aaaccaggaa agcgcaggtg cgcctaatcg
     9061 ttccaggaaa atattcacta acccgttttt agaaaacaac tcccgccaaa ctagagcgat
     9121 agaaatactg ccaccgatca aactaggcac ataatacaaa gaacgaaaga aagtcgttcc
     9181 tttgatattc ctcgttaaaa gataagcaat caatagacca aagatcagtt tcacaggtac
     9241 agatgcaaat acatagagaa aagtgactcg gatggagttc aaaaaacggg catcactcag
     9301 catctttata taattatcca agccgatcca tgagactgga tttcccaaac gataatcggt
     9361 gaacgaataa taaagtgaca agatcatcgg tatcactgtt atcaatagaa atcctaggat
     9421 gaatggagaa gcaaatacgt aaccgaccac attgtcttga tccaagaacc gttttagttt
     9481 ttcttttttc atgccttcct cctgctgcta tcctagaatg tttgacgcaa actcataaag
     9541 actctctgct gcttcttctg ctgttacttc ttcataaatg actttttcaa ctaaaagatt
     9601 gtattggtct tgaatttccg gattcaaagc actatcaaag acattcactt cgccgttgtc
     9661 catatcggaa atcatttcta aataatcaaa tgtcgcttgc aaagttgcat catctgcacg
     9721 agcgagctgt tctcgaatat tcgacatgat tggtacacca cgttctcctt ttaaaatttc
     9781 attggcttct tcactgtttt gaaagaaatc aataaactta gcagcttctt ctttatgggc
     9841 tgagcttttt gccatactca gcatttgcga agaacgtaaa gggataccag attctccatc
     9901 tgcttttctg cgaggtggat taatcaactg aatctccata tcttcaggag cccctgacaa
     9961 tatttctgtc aactggttac ttgatagaaa caccattgcc gcttctctat ccctaaccgc
    10021 ctgaaaagac agatccgtcg tacttgcagc tccaccacct ggttctggat gggccccttt
    10081 gtctaccaga tttttacgca gctggaaaaa atctgttaga tagtctggat tttcaaatcc
    10141 caagctgtta gatagatctt cccgattata aaaattcaat cctttctcaa cttgtggtat
    10201 ttgaataata cagccagcta taaaatcttc gaatcttgaa atagcataga ttcctaattc
    10261 ttcagtgatt tgatagctga tttgttcaaa ttcatcccat gtccaatttg aagctggttc
    10321 agggatattt aattgttcaa atatattttt attgtaagca atcgcaaacg aattcacccc
    10381 gttagacagt ccaactaatt gcccgtcgta agtcgtcgtt gctaaatagg attcatctgc
    10441 attagaaata tcaattatcc cttgctccac atattcatct aatggttcaa tctgattgat
    10501 gtattgagga aattgattgt tcagttggaa aatgtcccag atatcatctg atgctgctag
    10561 tgtacctaat tttgtgtaat atccttcata atcataaaat tcataatcga tcgtcacatg
    10621 gggatttttt tcttcataaa gctcgattac ttttactgtt gcatcgtgtc ggacttgcga
    10681 accccaccaa gccatgttca gcgtgatttt tttgtcatct tcttgcccac aagccgtcaa
    10741 gaagaataac ataacactta aagctaagat gattctcatt cttttcttca ttctctgcac
    10801 ctctacttcc attgttattt ttcaatatac tgtattttta tacagaacat atttattaaa
    10861 cgatcttttt caaggggaat aaaaaccaag acttgcctta tcgttctgcc taggatgaac
    10921 aactcaatac tttcaagaaa aattagatag tgctgattct tctttcatcg ctaaaaacac
    10981 ttcttgcttc aatgatggga ggataattac gcaaagaaaa aaggatatca gacaactgcc
    11041 caatatcctt gacatagcta aataagcatg cttcttcgtg tgcgctcttc cctaaaaaac
    11101 agaaaaataa ctagtaattc tgtatgaaat taggtacaat atacacgtcg atgcacaagc
    11161 attgactatg gcaacttgat tggtcagttc ccgctgactt ttcaagcccc gacaatttag
    11221 ctgctactaa attgtcgggt gcctttttta gtttttattc gtttttcatt ctatagaaag
    11281 cgcttcaata aatcaagaca tttttttgtt agaatgctaa taataacaaa aggttttaac
    11341 tcttcttatg tacattacag gtaaaaaaac aaaaaaattt ctcttttttt tgaattctga
    11401 acaaatagta ctggagtaca aaagacgagg aagagccact atctgctctt cctcgtcttt
    11461 tgattctcac ctgttattca tgattctttt tctcagtttc ccgatatttt tccattttac
    11521 gactaaaaag ctctccgcta cttggtggcg tatatgtgat ggcatttgct cctgcttgaa
    11581 tggtctcagc aatactttct tccgttggac cacctgtcgc aatgatagga agttcaggat
    11641 attttttacg aaaatggcgt actgcttctg cagtttcttt acctgcactg atattgataa
    11701 tcgaaatacc agctgctaac ttttcatcta tttctgtata tttcgacgtt accgtactga
    11761 taactggaat atcaactact cgacaaactt cttttactgt ctctaaaggc gtaggaccgt
    11821 tcaaaacgac ccctaacgaa ccttgcgctt ctgcgaacat gctcatgtag gaagaacgag
    11881 caccttgtgt caaaccacca cctacaccgg agaaaactgg aatgtcagct gcctcaataa
    11941 tgcttttagt aatcgctgga tgaggtgtaa aaggatacac agcaattact gcattcgcat
    12001 ttgtattacg tatgatcgca atatccgtag taaagatgat cgaacggatc aattttccaa
    12061 atatcttgat cccgcttgct tctaaaatga tttccggtac tcttacgata tcttttctca
    12121 attccgtcat gatttctggc gtaaattgtt ctgccatcag ccacttctcc tttgctatct
    12181 ccggtcatac tgattcaatt gatacgtctc gatgacctgg atgatttttt gcgcataacc
    12241 ggggtctgtc gcataacctg catcttgcaa tgcttgtgcg gcttcctgat agttggtggc
    12301 cgtaatcact ttttcataca gcgcaggatt ccaatctact ccttggacga acagttgtgt
    12361 atggtcatcc atggactgtt cccatgaatc atacactttg aagtctcctt ggatagttat
    12421 ccattcttcg ttaacaaatt cctttgtttc caggcttact ttcttctgat ccccataagc
    12481 cttgatcccg aaaagattat tgtatttgct agccaaggta ctttttcccc aatttgattc
    12541 taatatagct tgtcctaaaa tgatactagg aagcactcca taaccatctt gtagttcttg
    12601 ggcatgcgga acaagccgtt caataaattg ctgatgggat tgcgcttcat tttcttgctg
    12661 attatcagta aaaggagaag acagattctt caaggaaaaa acaaaggcta agagtatcac
    12721 tgctacaccg gcaaccactg ctggccaacg gatattcttg cgcttttgct ttttccactt
    12781 ttttttcgcc atgatcaatt cctacttttc atttaattca ttcagatatt cttctagcgt
    12841 caattggtgt ttggtgatat actcagcgtt ttctttaccg acataacgta agtgccaagg
    12901 ttcatatgtg atcttagtta tatcttcgtg tccttttgga taacgaacga taaatccata
    12961 ctgcgcagca ttatctgcga tccatttagc tccaggctga tctccgtaac ttgcatccaa
    13021 tacagtagaa ggataactgt tgtaccagtt ttgatcgacg acatcgactg ccagacctgt
    13081 gtggtgttcg ctgtatcctg gctccgtaat cgtttcttta gtaatctttg tcgcctcctc
    13141 ttctgataca ccttgacgac tcatcacatc ttggacattt tgttcgaaaa cttgttgttg
    13201 ggatgataca gaccggtaag ctgagaccat cactaatgga aatccagctg cttcagcagc
    13261 cttggcaaat gcttcatatt ctggagcaat gcgtttgtcg atcaagtatc cgttacttaa
    13321 tgatgccaat tgagtagact catcaatttc tttttctaat ttgtgatctg gaccaaccaa
    13381 aactagcttc caatcgtctg ttttaacatc tggcaattgt ttggacgtac gatcttttgt
    13441 ttctttgtcc tttaccttgc tgctggttgt ttgactgttc ttttctttac tagcagttgt
    13501 tttggtgctt gttcgttcga ctgcttgatt gccggcttga acatgcgaat catcatcgct
    13561 aaaaataaca tagcccattg ctgcgatcat aatcacaact gctccaaatc ctaaaaattt
    13621 attcacttga aaaatccttt cgttgttctt cacgttcccc attcgcctca tgaacgtaag
    13681 tttcttccag attttcattc acccaatcga gaagttcgat tttttctcct tcgatctgtt
    13741 tttgaacatc tgctggcaga cgaaaattca aaatatcatc atagccccat tcatcatatt
    13801 gaatacttac tttcaagtca aggtatctac cagcctgctg attatttttc aaagggatca
    13861 gctcgacttt tgctgctttg ctgctaagcc atttttgcgc gatgcgtgtt ttgatttgct
    13921 tgtactctgc aacggcaacg tttcgttttt cgggaaaaat aatcgtttga cgcaaaatct
    13981 tttgcgttag catccattca taatcagtga aaagattttt tactttctgc atcgcttcag
    14041 atggcagatt tttctcgcca tctttccatt tttgccattg ttctggactg atcagcaagt
    14101 attcatctaa aaaatttttt tcagtttcaa actgttctaa taatacactc ataataagat
    14161 caatatatac ttgatgcacg tttatcccct ccttttaact attctactta agttttgatc
    14221 aaaaagcacc tcttaaatcg ctgctttcat tttttttaat gtttcaagtc ctctcctctt
    14281 tattcttcgt gatttttgtt ataataatag acagacaaga aactcaatcc aactatgaag
    14341 gagcgttttc agatgaaaaa atatcaatgg ggaatcgttg gtcttggtac catcgcacat
    14401 gagtttgccg aaagcttcaa tcaagagacg agcgaactaa cagcagttgc ttccagaact
    14461 tcagaaaaag cggaaaactt cgctcaccgt tacaatattc caaaagctta cggaagctat
    14521 caagaaatgt tagacgatgc tgaaatcgac atcgtgtaca ttgctgtacc aaatagacag
    14581 catatcgacc atatcttggc agcattggaa gcaggcaaac acgttctatg tgaaaaagcc
    14641 atcacgatga ataaaaaaga actggctgac gctatgcgct tagcagaaga aaagaatttg
    14701 atcttagcag aagcgatgac aatcttcaac atgccacttt atcagcagtt acgctcaata
    14761 atggatacag gaaaactggg ggctttaaaa atgatccaag cacctttcgg cagttacaaa
    14821 gaaccagacc ctaaaaaccg gttcttcaat ccagaattag ctggaggagc tctgttggat
    14881 atcggtacgt atgctgtatc tttcgctcgt ttctttttga gctctcaacc tgaagtagtt
    14941 gcctctacaa tggttccttt tgaaacaggc gtggacgaac aatccgtcac tatcttgcgt
    15001 aacaaagaaa atgaacttgc tgctgtcagc ttgacttttc aggcaaaaat gccaaaagtc
    15061 ggtatcgttg cctttgagaa cggttatgtg acgattgctg attacccgcg tgctgatcgt
    15121 gcggagatct tatttacaga tggtacaaag gaattcatcg aaagcgggaa tacatctgaa
    15181 gcaatgaatt acgaaataaa gaatatggta cacatgattg aaggtgactt gcccaatcgc
    15241 tctctcttct tgacaaaaga tgtcatcgaa atcttggatc aaatgcaagt tctatggaaa
    15301 aatatgtaat tttaaaaggt tgtgaaaaag ctgttctgca tcaagtaata agaacagcca
    15361 aacaaaaata gctcctccta tttttcgttt ggctggactt attaccgcag aggaaagctt
    15421 ttgaacaccg tttaagaaag aggttgtgag cctaccgttc agctccgagt cacaaggagc
    15481 aatttcaaaa aacagcttct catgtttgtt gaatattgtg acttgtgacc gaggagttga
    15541 caggagaaca ccgtttaaag aagaggttgt gaaatcagct ttttgacctg aatattagct
    15601 gaattcacaa cctctatttt tggatttttt gttgggagaa ttctgccttg atttcaataa
    15661 aacttttaaa agactgcaaa aactggaaca attctgctcg atcctcgaat tcagggcgac
    15721 tagtcggcag aggcatttgc cgatacaata cataaacttc ttcaatacgt gttaaaattt
    15781 gtctgccatc atttgactct gaaaatgttt ctgcagtata aatcaataaa ccatagatat
    15841 gttttccata ataagctggt tgctggattc tctctagatt ttccagcatg tctttaatca
    15901 cattggcctg tgctcttctc atagagaagt aagtttcgta gtatagcggc tgtctgagcc
    15961 agtagttttc ttgatgttct ctggcatctt cttggctttc gcgaatgaat gtcagtaaat
    16021 gttcgcattt gatctgcaca tcttctttat tttctgataa aagaaattct gccatttgtc
    16081 tcaaaatatt tcgaaattct ttttcgatct gtatttggtt ttccttcagc tgcttcgtac
    16141 gatctggcat gtaaacattt gcaagcaaag caaatactaa tccaatcgcc attaatcccg
    16201 cttcattgcc gatcagctgc caagacatgt tttcctccac taaataatga gtgaccaaaa
    16261 ccgaatttac tactatccct tcggttaatt tgaagcgaga ggcaagcggg atgaacagga
    16321 ataaaaaaag actgaagcca aaaatagtat acccaacagc aaaaaaactg aacagtgctg
    16381 ttgccgtagc taatataaag gctgcgattc gattcatgcc cgtacgcaat gtagagcgct
    16441 tggtatttcc tacacttaat aatgcaatga tccctgcagc tggccaatac aacagcgata
    16501 agctacccgc tgtgaccatc gaaaagaaga cactgatcac tgttttgact gttcgcattc
    16561 ctatacgcat ttacttcccc cttttttatt ttaattatac ttgaataatg aaaaactagc
    16621 tatcagacaa aagtttaggt atgatagtaa aaagaccaaa aaggagaatc tctatgcaat
    16681 ttggccgttt tcgactaggt atgcgtacga tcaaaagtgc cttagctgtt tttttatgta
    16741 tcttgttttt tcatttgact caacgaggaa tcccgatgat tgctgcatta tctgctgttt
    16801 tttctttgcg tcaggacttg actacaaccg tttcttttgg aaagtctagg atcatcggca
    16861 atacattagg tggtacatta gctatcattt atttttttgt caaaagctat tttcacaatg
    16921 attttttggt agaattgatc ttgcttccta ttctagttat tattgtgatc gtcgtgtcag
    16981 atggtattaa caataattcc ggtatcattt ccgcaatagc tacgttgttg ctgattgcgt
    17041 tgagcatccc tcaaggcgaa tccgctttgt atgctatcca acgtgtacta gatactttta
    17101 tagggacatt cattgcaatc ggtatcaatt tctttcttcg tcctcctgaa acagaaaaga
    17161 aggaagaact atcagaagat ttggtcgaac tccaaaagaa agaacgattg ctaagaacaa
    17221 atttacaaga gatagaagct aagatccaaa aacaaaagaa aaatagcgag gactaatttt
    17281 cttttgcaat aaaataaaaa aatggagaga agaactttaa aaagtcttcc tccatttttg
    17341 attgaacggt gaagtgtact actttattct tccttcatcg agttttgttc tgcctctttt
    17401 ggcgcttcat acatatttac ttggctagta gtcccacgtg tcgacaaatt ctctacgatt
    17461 tccttcaagt caagtcctgt tgtcgctttt agtgtttctt gagtagaaga aagcaaattt
    17521 gtggcataat ttgtcactcg gttcgctcca ctggtttctc ctgaactgct tcctgtatcg
    17581 acaacagaga ttttttcgat atttcctagc ggctgtgctg cttcgcgcat caattgcggt
    17641 agcatatcga taaccatact caagacagct gcttcgccat attccttgaa ggcattggcg
    17701 atcttttgtt ttgcttcggc ttctgctttt ccttttgcta gtgctgcttc ggcttctgct
    17761 tgtccagcta aacgtgtctt attggcttcc gcttctgcca gtgcttccac acggaatcgt
    17821 tctgcttcgg cttcagtcac ttctttgact ttttgagctt gtgcttcttg ttctttagcg
    17881 taccgatcgg catctgcttt tttcttcact tccgaatcat attgcttttc acgacgtgtg
    17941 atttcttttt cttccagttc gatttgtttt tgacgttcta cgattttaat ctgcatttcc
    18001 tgttcgatta cttgttgttg tgctcgggca ctttctaaat tgtaggcttg gtctgctttt
    18061 gctttagcaa catcttgttc ttgtttgtag gttgctaatt tcagttcttt ttcttttaat
    18121 gattctgcga tctctgtttg tcgctgtaat tcagctgctt gtgattcttt ttctgcttga
    18181 gcttttttga tacgcgtttc ttttagagct tccgcttctg ctatatctgc atctcttttg
    18241 acttgggcga ttcttggttt ccctaaagag tcaagataac cgtttttgtc tctgacctct
    18301 ttgatagtga aagaaacgat gatcaacccc atttttgcaa ggtctacaga agcgacttct
    18361 tgtacgcttt gactgaactt atcgcgattt tgatagattt cttctacagt catagaacca
    18421 agaatcgagc gcaagtgtcc ttctaatact tctcttgctt cattttccag ttcttctctt
    18481 gtcttgccta aaaactgttc tgctgctgta gcaatctctt ctacagatga accgattttg
    18541 atgatcgaag taccatcaca catcaccggt acgccttgtt ccgtatacac ttcaggggtg
    18601 gagacgtcca atttactcga taatagactg atccgattcg aacgttgaaa aactggcaag
    18661 acgaatgcgc cacctccacg cacaattttg attttgttat tgctttcatc aatgtgcaca
    18721 tttttgcttc ctaaataact tccactgatg atcaacgctt catccggttt tgctgtctgg
    18781 tacttcgcta caaagacgat cagcaacatc agtaaaatca aagctgcgat tgcgatcgcg
    18841 ataaaaacaa ctggtatttc catttaacac acgctccttt aagcttttat catgctttca
    18901 taaggcatga cataacagat tctttccttg atctcaatga tcaatacttt cgttccccgc
    18961 tcagctgtct gttcttgggg gctgtaaaaa caagctggac gactaatgga accggtaaca
    19021 cttttcaact gaatttctcc catacctcgt acagggatcg gtgtgatcac aacagctact
    19081 tgtccttcca gagttttttc agaagacgac atcgttgatt cggcatgttt catcggcatc
    19141 aatatataga aattaagcaa aaataccaac actatcgata tgcctccact agcaataaat
    19201 aaaaataaag atgattgatc tgttaaacgc tcacctagaa aaccaaataa gcttgtgaaa
    19261 gttaaccaag ggataataag catcggatca agcgggccat caaaatcgaa tacatctcca
    19321 aaaataatca ataggactgc caatcctgca caaatcagca atgtatacca ataaatcgtc
    19381 tcaagtgcga ttccccctat catatacacg cctccttcca tttctacgtc tatcatacca
    19441 atgtttgaaa attctgtata gcttctttta ccgactcagt ggtgtttttt ataggaaggt
    19501 tgtgtttatc gttgacaatt tgttaaattt ttgttttcat gttaaaattt tcacaataaa
    19561 ttctttcgag gtagcctatg tttccttttt ttaagaaaaa accattaaag ctccagaaca
    19621 cgatcatcct tgtcgtttgt ttctccacat tcgtttcttt gattgtttct gccatattga
    19681 tcaggaattt tattctttcg atgaaccgat ctagtgtgtc agataaaatc tctagcattg
    19741 ctaaaatcgt tgccaatgat aaactcatcc aaaaaaagct gcagactggt gacccgacac
    19801 atgcgattca aggaataaca aatgaaatca tgattgcatc gaatttagat tttatcgttg
    19861 tcatggaccc tgaaggcatt cgatattctc acgcagaccc aagttacatc ggtcttcctt
    19921 tctcaagtca tgaagatgtg aaaaaagtga ttggaggaca agaatttttc tctgaaaaag
    19981 aaggaatgtt agggttcggc ttccgctatt tcgtccctat ttattatgat caagagatta
    20041 ttggtgcagt ttgtgttggc ttaacaaaca acacgattga caatcaagtc aaagatggac
    20101 aaaaaatgat tgttttttca ttgattattg gacttagcgt aggcatcata ggcgccgttt
    20161 ttcttgccca aaaaatgaaa aaagtactgc ttggacttga accacaagaa atagcagaac
    20221 agttaagtga aaaaacgatt atcgaaaatg aagtagatga aggaatctta gccatctctt
    20281 ctgataaaac tatcctcttg atcaatacac ctgcaaaaaa cattttctac caaacagagc
    20341 agctattgga tttcgaagta ggaaaaaaat cagtgataat ctatatgacg ttttgtttaa
    20401 agagacgatt gagcatcaaa cgaccgttcg gactcaatcc atgtatttaa atgggataga
    20461 aactatttct agcgttacac ctctttttag caatgaccgt tttttaggag cagtcgcaac
    20521 tttacgaaat cgatcagaag taatgaaatt aatggaggag cttgggggga cgaaacaata
    20581 tataaactcc atgagagctc aaacccatga attcatgaat aaacttcatg tcatttctgg
    20641 tttgattgat ttgaagaagt atgaagaagt cacccatttt atccagcagc taaatcaaaa
    20701 ttataaaaaa gagattggcc aagtctcaag tctgatcaaa gtacctgcaa ttgccggttt
    20761 tttattaggc aaaataaacg aagccaaaga acaatctgtt gaaatgctgt tagaaagcga
    20821 ttcttttatc cctaaaatgg agatggatga ctccatccat tcacttttgc aagtgttagg
    20881 gaacttactt gataatgcaa aagaagccgt gctacaaaaa catgaaagaa acggacaggt
    20941 ccggattcat ttaaactatg acacagaagc tgaagtattc atcgtgaccg tctgcgatga
    21001 cggtgtcggg atatcagaag aaatctcaga aaaaatattt acgctaggtt tttcgacgaa
    21061 gggaatcaat cgtgggtttg gattgaatct catccattca atcgtcaaac gccacggtgg
    21121 atttttagaa ttttccaaac aaacaaatgg cggtacaatc gtctatctag aattaccaaa
    21181 aaaggaagat caaaatgatg acaaatgtcc tgataatcga agatgatcca atggttgcag
    21241 aattgaatcg tacttttgtg gaaagcatcc ctaatatgaa cgtaatcgaa agtttcagaa
    21301 atgtagaaga aggaaaaaaa tatttcagac aaaaaaacgc agatctgctg ctgcttgatg
    21361 tatacatgcc tggcgaaagt ggtatccatt ttttatcttg gcttagacag caaggaaatg
    21421 atatcccagt gattttgatc actgctgcag atgatatcga aaccataaag aatgtgatcc
    21481 gctacggtgc cttagattat ttgatcaaac cgttcacttt gcaacgtttt cagctggcga
    21541 tcgaaaagta tcttgctttc tctcagacaa tccaaacgac tgaaaaagcc gatcagaaat
    21601 tgatcgatca agtattcaac cacaccactc ccattcacga aataccatca ttcatcgatt
    21661 tgcctaaagg tctgtcaaaa ctgactttaa aaaaaataag tgcatttatt ctaaaagaag
    21721 atactatttt ttcaacaaaa gaactggctc aaaaaagctc actgtcacgt atatccgtca
    21781 agaaatattt gaatttttta gtagaacaag atatattgaa cgaaagaatc aaatatttgg
    21841 aaatcggccg gccgctaacc tgttatgaat tgacaaagaa tgggcggaaa aagctcacag
    21901 attactgttg agtcatcgaa ttatcccata caaaatagtc caagtataca gaagtaacaa
    21961 ctgtttactt ggactatttt taaacatttt attgacgaat atccatgttt tcttatctta
    22021 attgacgggc tttaggaaga gatacctcat ttttcgtttt tccagtttct attatttcac
    22081 gaaagttctc gaaacttgtc gaaatcatat ttgataatgc ctcatctgta tttgaaccta
    22141 catgcggggt tacaagaact ctagggtaca tttctactaa ttgctggata gcagggtctg
    22201 gaatcgtctc ccatggcttg aaggatcgga aaaaaacctc tgtttcattt gcaaaaacat
    22261 cggttgcaaa accagctaaa tgattgcttt tcaaagctct taaaatagct tcattatctt
    22321 gaagctctcc acgggctgta ttaatcaaga tgctaccttt tttcatttga gctaaaaatc
    22381 cttcattgat catttgatcg ttttcacctg ggatatgagg tacatgaata ctgacaatat
    22441 cgcttttggc taataactct tcaagcgagt ggaacgtcaa tactttttta gcagcttctg
    22501 tctgatgaat atcgtagccg atcactttgg ctcctagtcc cttaaacaaa acagcttccg
    22561 tcaaccctat cctgcctgtt cctatgatcc ctactgtgca atttctgatt tcacgactaa
    22621 acatttgctc atccactcga aaatctttga aagatgttcg gatcgtcgta tacgcagtat
    22681 ttctcaaaag catcatggca aaagtcaaag ataactctgc tatcgcattt ggcgaatacg
    22741 atggtacacg ggctactgtc ataccaaaat cagctgccgc ttgtagatcg atatgattga
    22801 ctcccacagt ccgtgtaaaa acataacgaa tcccatattc ctgcattttt gcaagattgg
    22861 tctcatctgc tatacaattt cccctcaaca atacagcatc atggtccttt gctgacacga
    22921 tattgtcatg tgtcaacagt tcttcataaa gactgagatc ataatggtaa atattcaatt
    22981 tttcaaaaaa atctatctcg ttcggacgaa caccgtaaca tgcgattctc atactttctt
    23041 cctccatttc ttatgaaaat aaacctatgc catgaatcat ttgtaataca acgatccata
    23101 caggtgtcag taccacagca aaaatagttg acagtaagga tgcattggag gctaaaagtg
    23161 cctccctatc aaaactgata gcataggctg ctgccactgt tgcagctggt gtagccatca
    23221 tgataacgat tgttgccagt gcttcaaaat tgactggtag aatattcgtt gccgtcaaaa
    23281 ctgctagaat cacgatattc aatgcaggta caaataccac tttgactaga ctgtaatacc
    23341 atgaagtttt ttcagatgca gcttttttga agcttacttc acctaatgtt gcgccgattg
    23401 ctagccacgc caatggtgaa cttaaaccag ctaaataatc catcgactga aatagccacg
    23461 gtgcagtctg gtcaattcgc aaaaacgcta cttggcttat ctctccttct gcacctgtaa
    23521 ctgacacttg tggcagatac ccttggaaca gccaaatgaa aaggccggca aaagtagcga
    23581 taatgattgg attgacgaac atcgctttga tatttttagc ttccatcttc aagccactca
    23641 tttttatgta tccataagaa tacaaaaaga ttcggtagcc aatattgaaa attgaggaat
    23701 acatcacgcc gacaggacca taaatcgcac tgacgatagg cgttccgaaa aaggtcgtag
    23761 aaccaaagat cgtcaggaca cgcaacgttg tttgcttatc ccctttatag cttaagaaaa
    23821 aaggttttga aactagaata agaataatat aaataactaa tccccaaatc aagacattga
    23881 ttccttgcat cagtaattct gtattgatat cttgcatgaa agctcgaaat gccagtgctg
    23941 gcaaagccac tgttaagacg actttcgata gaatttttcc aacagattca gaaaaaatcc
    24001 ccttttttct acaaacaaac cctaataata taataaaaac tgttgaagtg attgcactga
    24061 caatcgacat atctgtcaaa gtcgatcgaa aaatgtcaaa taagttcatc tttctcctcc
    24121 taattatgtt catttattca caataaaaaa agcttttatt ttgctaatac gtattaacat
    24181 ttttaatttt atctttacat tgttacttat tgaacaatag gaaattaaag aaacttttga
    24241 aacttatgta aagtgatt
//
LOCUS       DADLIO010000039        24140 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.039, whole genome shotgun sequence.
ACCESSION   DADLIO010000039 DADLIO010000000
VERSION     DADLIO010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24140
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.039"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(<1..386)
                     /locus_tag="JOX41_001691"
     CDS             complement(<1..386)
                     /locus_tag="JOX41_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAY6449435.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQDMLDYYYFEKNLSY"
     gene            complement(458..1390)
                     /locus_tag="JOX41_001692"
     CDS             complement(458..1390)
                     /locus_tag="JOX41_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HAY6449436.1"
                     /translation="MLKLKEKEYIIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGL
                     LNKLTISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITE
                     EKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKEL
                     YANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEP
                     MDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLD
                     EIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            complement(1829..2281)
                     /locus_tag="JOX41_001693"
     CDS             complement(1829..2281)
                     /locus_tag="JOX41_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAY6449437.1"
                     /translation="MHLNKYWILEEIEKLFVEFGSDAINPYKIIKYSDIDLIETDLGN
                     KTLGQTIHNKRCYVILINQNLSPSMKRFVLWHEIAHVRLHKGICTAAFRANNLSCMIY
                     GIEAEANMFAIEMLTRTIDEQDLSDMSQFQIIEYLGLPHNLEHLVLQH"
     gene            complement(2294..2704)
                     /locus_tag="JOX41_001694"
     CDS             complement(2294..2704)
                     /locus_tag="JOX41_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAY6449438.1"
                     /translation="MLLDRIKILLKERSMTLAELERKLNFGNGSMSRWNKSTPSGDKI
                     QKVADYFNVSTDYLLGRTDKRHYYDLTEKDKQDIALQAEKLLEGLNSDAETNYYGEPL
                     DDEDKEKLYDAIQLALALTKVKAKKKFTPKKYRQ"
     gene            2979..3191
                     /locus_tag="JOX41_001695"
     CDS             2979..3191
                     /locus_tag="JOX41_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAY6449439.1"
                     /translation="MTLKQQVLIALVKKGWSQRELARRMGISITYLRDIFIEKRKPKE
                     RLKQIEELLDIKLEVDSNDQPSEQEA"
     gene            3194..3406
                     /locus_tag="JOX41_001696"
     CDS             3194..3406
                     /locus_tag="JOX41_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449440.1"
                     /translation="MVQRLSKAEFKEKYKYSESTYQRRMKEFKKSRFSEGYNAVTSKE
                     ITIDVDLYEQFRTWRSKNRFRVRAVC"
     gene            complement(3698..3922)
                     /locus_tag="JOX41_001697"
     CDS             complement(3698..3922)
                     /locus_tag="JOX41_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004401476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HAY6449441.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            4000..4188
                     /locus_tag="JOX41_001698"
     CDS             4000..4188
                     /locus_tag="JOX41_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449442.1"
                     /translation="MAYTLQQEHQILGLIKQRRKQLQDDRAALRKADELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            4514..4849
                     /locus_tag="JOX41_001699"
     CDS             4514..4849
                     /locus_tag="JOX41_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449443.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            5082..6023
                     /locus_tag="JOX41_001700"
     CDS             5082..6023
                     /locus_tag="JOX41_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
                     /protein_id="HAY6449444.1"
                     /translation="MSKSTLEMSHQEWLEDRKKGIGGSDVGTILGLNKWKSPYQLWLE
                     KTGQVVLEESGSEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPIIDGSQATADFLKEKYADVEDVQTT
                     LPIHFDELVEQKNELKRTKKEIESAIRQVDNEIISELGKREASIGITQKNIISWKFVR
                     TRRMNSKKLAEKYPDVANDEEIYNVTESRRLTEREIK"
     gene            6025..6915
                     /locus_tag="JOX41_001701"
     CDS             6025..6915
                     /locus_tag="JOX41_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HAY6449445.1"
                     /translation="MATNESLKNQLAAKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            6958..7758
                     /locus_tag="JOX41_001702"
     CDS             6958..7758
                     /locus_tag="JOX41_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAY6449446.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWNLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADDIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            7773..8624
                     /locus_tag="JOX41_001703"
     CDS             7773..8624
                     /locus_tag="JOX41_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAY6449447.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGAIA"
     gene            8825..9286
                     /locus_tag="JOX41_001704"
     CDS             8825..9286
                     /locus_tag="JOX41_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010781228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAY6449448.1"
                     /translation="MPKILDACCGSRLFWFDKNNSDVTFMDCRQQYEELSTGHVINVD
                     PDVVADFRDMPFEDDVFDMVVFDPPHLRHVGENSWLAKKYGKLDELWPEDIRQGFAEC
                     MRVLRPSGTLIFKWNEEQIPLSDVLEAIGEQPLFGNKRSKTHWLVFMKKFS"
     gene            9312..9764
                     /locus_tag="JOX41_001705"
     CDS             9312..9764
                     /locus_tag="JOX41_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449449.1"
                     /translation="MKIVLNKCFGGFGLSHEAKMEIFKRKNIEVFPYINNFSYDSDDE
                     YTRYTGQKLGSMDFIYYFKKDPKIDKVTGIYSEIDRLYGIADDSSFSSDSNRGDKDLV
                     AVVEKLGSEASGPYASLKVVDIPDGAEWEISDYDGVETAHYGFQTGSI"
     gene            9870..10064
                     /locus_tag="JOX41_001706"
     CDS             9870..10064
                     /locus_tag="JOX41_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449450.1"
                     /translation="MDASEVVNKINSLKEVFGDVEVVINAQGYDNEFFKQITDISIQQ
                     GMEDEDGNFIDEVAILVTCE"
     gene            10095..10388
                     /locus_tag="JOX41_001707"
     CDS             10095..10388
                     /locus_tag="JOX41_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449451.1"
                     /translation="MKLKDGFYSSGHGIGGLMLDMPTKNPKTRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVVRLVDMEVIKS"
     gene            10418..10858
                     /locus_tag="JOX41_001708"
     CDS             10418..10858
                     /locus_tag="JOX41_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAY6449452.1"
                     /translation="MSVIPQLEGEEAIVNILENIDIKQTRKNARRLLKRYRNLERLVG
                     PVKIDFSVMTVTKNLKFTIDSQNEEIIEAISTRDSVIEALTRLSRIHFQVLYYSYCFP
                     NKMSMYQIGEKLGYSDRTIERMKAVALVEFAEAYKSGELISRTK"
     gene            10933..11400
                     /locus_tag="JOX41_001709"
     CDS             10933..11400
                     /locus_tag="JOX41_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HAY6449453.1"
                     /translation="MVLFDVKKYETPSAKDVDMERTKHNVAVFLSAYLSARCRVGQHR
                     EPKVTASYSLVPPSTADHIFEAERMLIDKEEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            12147..12377
                     /locus_tag="JOX41_001710"
     CDS             12147..12377
                     /locus_tag="JOX41_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449454.1"
                     /translation="MRNYWYVSLTNEYPRTIDDCSVRVVRSVQIKGKYSIVEMGREAE
                     PCEIDACKLVYCGHGFYDEPNIQNNINKNLRD"
     gene            12536..13369
                     /locus_tag="JOX41_001711"
     CDS             12536..13369
                     /locus_tag="JOX41_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small subunit of terminase"
                     /protein_id="HAY6449455.1"
                     /translation="MARQRDPRRDEAKRIWLESNGEKQLKEIASELNVSDSQVRKWKS
                     QDKWSAELISNVTNGKSNVTNQGGAPIGNQNAKGNKGNSRASPPVGNKNALKTGEYET
                     IFFDTLTDNEKDIYSSLNDDPSFALSEEIRLLKIRQLRMMKRIQQAEAGLNDEEVERL
                     QQLRKIKTPIEKNGKKLEIKREVMQDVQISRKKHRKIDDILSIEDSLTRISNQLAKAI
                     KQMNELYMNEYRTDLIKAQTDKIQAETNEIGGNNSGEEIEEWKQAVLNAANKRAVKEN
                     E"
     gene            13362..14777
                     /locus_tag="JOX41_001712"
     CDS             13362..14777
                     /locus_tag="JOX41_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAY6449456.1"
                     /translation="MNNEFIPFADIGSAIDYYYDKPVAFCQDILHLNPDEWQENVLND
                     LAEFSKVSVRSGQGVGKTALEAGAILWFLTCRPYAKVIATAPTMKQLYDVLWAEVAKW
                     LNDSLIKNLLKWTKTKIYMVGDSERWFATARTATKPESMQGFHEDHMLIVVDEASGVS
                     DPIMEAILGTLSGFDNKLLMCGNPNNIEGVFYDSHNSDRDKYRVHKVSSYDSKRTNKD
                     NIEMILKKYGKESDVARVRIFGEFPKGALDSFISLETVELATEKQISDSLVNKTKVAH
                     IGVDVARYGDDSTILFPRIATRALEYEKYSKRSTMETTGYVINMAKNLMSQYPSIDKV
                     MIKVDDTGVGGGVTDRLEELIEDKHYPFEVFGVNNGSTSEDDFYDNLGTQLWGNIKEM
                     LEENMTANLNGEQPVIELPSDSSLIKELSTRKFKMTSRSRIRLESKDDMKKRNIGSPD
                     IADALALAFYEPPSHYQFIQF"
     gene            14789..16318
                     /locus_tag="JOX41_001713"
     CDS             14789..16318
                     /locus_tag="JOX41_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAY6449457.1"
                     /translation="MISTVLSLERYKKLRVKYATQIEDGMFDPNGFIEDMKPFFADRE
                     RKYLAYTSEKNEIDNRPKPNTDIVKVNNKLHAGMYSIVVDQAVNHFTGIPIKWDYDVS
                     EQKRTLIQRLKDKFLKNDIELPTVPEAFNKLTSNLDSMRFAMLDSETATFQGACGVAF
                     RLLEPVEEDDGWKLRASNIEPWRAERYGNAGIYIKEKYDSYQKKFFQEMKVMTRNKIL
                     TYACYGDLNFVTSGTFKKIDETDNPLGTITLAEFKNNTNRYCDFEVAEEIGDAIDRAL
                     SDQQNEIEQFKLAYMLVTGTTMSKGTAKEMMNQLGIINLKAPTAKAEYVTKNLAKDFN
                     EYHMDLLKKQFYTICKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAETIAAFLKFHDKVEIEPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMMELESGSAYPDSEYNFGGGGNSDDRNEVLDQTSRTGGSSKAQTRKSD
                     T"
     gene            16410..17288
                     /locus_tag="JOX41_001714"
     CDS             16410..17288
                     /locus_tag="JOX41_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HAY6449458.1"
                     /translation="MMEFYSTSNQKKYREYVEKNYKSLKMYDAKYKEFIDEFFPPFDY
                     AKVNRLLQIRSDVFKILAEYAMDADVNQYFSDRLEEILQRTYSSNANVFVQLLNVDIP
                     NYLPENEIKHYLNYPWSGKTFSRRLWGNISSLEQKLSNAIVKSVASGEGVIHALNTMR
                     LDSEICDMFKLEESKYNKAIENLVRTEYAKFAQDGIEKSYLETGIEEYNVLTAKDERV
                     CRICGGKASKNPYKLKDAVIGENRAPFHSRCRCTDVPNLPKLGKDIDEEYDRLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            17290..17607
                     /locus_tag="JOX41_001715"
     CDS             17290..17607
                     /locus_tag="JOX41_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449459.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYEKMGCIVVRTDYKEGK
                     SSN"
     gene            17656..18357
                     /locus_tag="JOX41_001716"
     CDS             17656..18357
                     /locus_tag="JOX41_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HAY6449460.1"
                     /translation="MVEWWGATIKTQSNAGRENESWGERRMSMKHKSLMPMNLQYFAE
                     GDDQKFSFDDFKSFVESNEEAQKFIQSQSQSVADKQLEAWKQNNLDKIKQDTIKEYEE
                     SKKNKSPEQIQLEKLQAEFEAEKALRVTSDNKAFVAEQIAGLELDGELKESISQFMLN
                     NLVSSDTDFTKNAVEGFTSVLNAINEKHADALKELQMKSAFGGTQQSNNQVQQNNETL
                     TNPEEQLGQILQQFN"
     gene            18372..19262
                     /locus_tag="JOX41_001717"
     CDS             18372..19262
                     /locus_tag="JOX41_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 domain-containing protein"
                     /protein_id="HAY6449461.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            19285..19500
                     /locus_tag="JOX41_001718"
     CDS             19285..19500
                     /locus_tag="JOX41_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449462.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            19512..19853
                     /locus_tag="JOX41_001719"
     CDS             19512..19853
                     /locus_tag="JOX41_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449463.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            19853..20224
                     /locus_tag="JOX41_001720"
     CDS             19853..20224
                     /locus_tag="JOX41_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449464.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            20217..20612
                     /locus_tag="JOX41_001721"
     CDS             20217..20612
                     /locus_tag="JOX41_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HAY6449465.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGEVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            20614..20991
                     /locus_tag="JOX41_001722"
     CDS             20614..20991
                     /locus_tag="JOX41_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449466.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNNPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            20992..21600
                     /locus_tag="JOX41_001723"
     CDS             20992..21600
                     /locus_tag="JOX41_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAY6449467.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            21600..21941
                     /locus_tag="JOX41_001724"
     CDS             21600..21941
                     /locus_tag="JOX41_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449468.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGTVVEDAAGVMEE
                     MQTATDKQSVKKALSRAYSFIADTLFEGQFTGEDYCKGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            22183..>24140
                     /locus_tag="JOX41_001725"
     CDS             22183..>24140
                     /locus_tag="JOX41_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HAY6449469.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANPFVLIIGAVVGAI
                     AVFGYFMATNEELRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVEGVK
                     DAWSGTKEWFSNTWKGIKDGATGLFDKTVETSRNAVDSVKNAWSNMKKWFSDTWQSIK
                     DSAREKWNGIKGSIMSVAGPLITGIKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LAPVLFITSMISGGWEETKNNMIAVWNNIKESAINIWESIKNIFVSYFTNIYFAALNI
                     WTGFKLTLINIWNEVVNQAKSIWLNIKY"
BASE COUNT         8554 a         3551 c         4800 g         7235 t
ORIGIN      
        1 ttatatgata aatttttttc aaaatagtag taatctagca tatcttgtat aagattacta
       61 ttaacgtttt ttacaagtac atcatctttt atatattttg aaattaatga tagataaacc
      121 tgagttgttc gataggaact ttcttttaca gttggcttgt atttttcatc ccatttagtt
      181 tttaattctc caaaagttag tggtaattct tcatttcgtt ttattttttc tgcgattttt
      241 tcattcaaaa gtaagttagc ttgattccaa gcttggcgtg aattgctaga taaagtaacg
      301 gacacttttc tctttttttc agttaaggga tccgtataac gttcggtgta cttaaatttt
      361 ttgtcattta ttttttctaa ccacattatt tctattcctt tcgaatatac gttcctatta
      421 attgttaaaa gaaaaagccc gaaggctttt tatatattta atcttttgac aattctaaag
      481 atcgtctata ttgttcagct ttagctaatt ttgtaaatgt tactgttcca ttataatttt
      541 ctaaaacaac tttctctatt tcgtctagtg aaactttgaa aaattctttt ctttgattaa
      601 ttttattaac ttcttgtttt ctaaaatgat tatgcaattt agtttccaaa gacggagcgt
      661 cctctgaaaa aatcatcgca tgaacgtcaa attcaaatgg aaccgatgca ctactcaatt
      721 cttttattct atccataggt tctaatcttc tagtcatacc aattttatat atgtcttcac
      781 caaaagaccc aatattacta attacataca cataaccggc tctagtattt aattctcttt
      841 gtaatacatt ttcacgtata acttctaatt cttttaattt ttcttccagt tcttgaattt
      901 tatttgcata taattctttt tccacatctg cattagcttt ttgcatatat gcgattaatt
      961 tggaaatttc agaattgaat tgacgttgtt ctttatcaat acgtttcttt tcacgatcaa
     1021 tttctctacg aactttttcc tcttctatca tctgttcttt tattgctttt tgttgttctt
     1081 tttcttcggt aattttcact aaataagagt aatgaagttc tagttcttga agtttaaact
     1141 ctaaaagacc cttccttaat tcagcattgt cattcttgaa taaattatta attttatcaa
     1201 atatttttat gattttttcc ctagtcgagt ctatattaga aatagttagt ttattgagta
     1261 atcctttcac ttctgaatca aatggaatga gcattttttt ctttaaatta tttttctctc
     1321 gtttatttaa aataagaggg acagaaacag catcgtcaat aatatattcc ttttctttta
     1381 attttaacaa agaaagctta ttttttattt cagaagatga agtttcttct atatttgaaa
     1441 cgataagtga agaatagaca ttttttaatg tttcatcata cttttgattt atttcatcat
     1501 ttaaatcttc tttctctttt tttaataaaa taatatcatt ttttaacata gtaatttgtt
     1561 tatttaaatc tgatagtgtt tcttccttac ttaatataaa tctttctcta tcatgtaatt
     1621 tatttagttt ttcatcattt ttttgttcta attcataagc ttcttttttt attgtgttag
     1681 ctttcgacag tttagtgatt cctataatta ataaaataag tccaatcaat aataacattc
     1741 aaaactcctc atttctttga tataattatt gtagagttta ctcagaaatg aggaaagagt
     1801 ccatgtgaaa gcatgggctt ttttattttt aatgttgtaa tactaaatgt tcaagattat
     1861 gaggaagccc taaatattca ataatttgga actgactcat atcagataaa tcttgttcat
     1921 ctattgttct agttaacatt tcaattgcaa acatattagc ttcagcttct ataccataaa
     1981 tcatacaact aaggttgttt gctctaaaag ctgctgtgca aataccttta tggagtctaa
     2041 cgtgggctat ttcatgccat aatacaaatc ttttcataga aggtgatagg ttttgattaa
     2101 ttaatatcac ataacatctt ttattgtgta tcgtttgtcc taatgtttta ttccctaaat
     2161 cagtttcaat taaatctata tcagaatatt tgattatttt atatggatta atcgcatcag
     2221 atccaaactc tacaaataat ttttctattt cttctaatat ccagtatttg tttaaatgca
     2281 taccaaagcc cacctattga cgatattttt taggagtgaa ttttttcttt gctttaactt
     2341 tggttaaggc aagtgcaagt tgaatggcat cgtataattt ttccttatct tcatcgtcta
     2401 aaggttcacc ataataattt gtttcagcat ctgaattcaa gccttcaagt aatttttcag
     2461 cttgtaaagc aatatcttgt ttatcttttt ctgttaaatc ataataatgg cgtttatcag
     2521 tacgtcctaa aagataatca gttgatacat taaagtaatc tgcaactttt tgtattttat
     2581 ctccagatgg agtactttta ttccatctag acatgcttcc atttccgaaa tttaactttc
     2641 tttcaagttc tgccaacgtc attgaacgtt cttttaataa gatttttata cggtctaata
     2701 gcataggata tgcattcctt tcaaaatacc gacaaaaaaa gtatttttct gcaaattatc
     2761 tatttacaaa tagagaattt gcagttatac tagttttgta agcaagatat ttacggcata
     2821 caaagactaa aagcaataaa ctaatagtct ccccagacat cagtaagctc gctttttgtg
     2881 cgctgtattt tgtatgctta cataatagca tatttgcagt ttttgtcaaa cttattagac
     2941 aaaaatatta gaaaatattc gataaggggg tatgaagcat gactttaaaa cagcaagtat
     3001 taattgcttt agtaaagaaa ggttggagtc aaagagagtt agctcgacga atgggtatat
     3061 caattactta tttacgagat atcttcatcg aaaaaagaaa acctaaggaa cgtttaaaac
     3121 aaatcgaaga acttttggat atcaagttag aagtagattc taatgatcag ccatcagaac
     3181 aggaggcgta aaaatggtac aacgtttgag caaagcggag tttaaagaga aatataagta
     3241 ttctgaaagt acttatcaaa gaagaatgaa ggaatttaaa aaatcacgtt ttagtgaggg
     3301 gtataacgca gttacttcca aagaaataac aattgatgtc gatttatatg aacagtttag
     3361 aacatggcgt tctaaaaatc gatttagagt tagagctgtt tgttaatagc taaaaaatct
     3421 aaattcacca cttctgaaaa gaggagttgc tgctctcctt tcaagtttgc caaagtccac
     3481 gttttttcat tttggcaact cctcttcttg gaggtggtga cggcgagaga cgaaggaggg
     3541 atgacatgaa ggaagaatca aaaataggga ttttgaatga gaacaattac acaagattaa
     3601 ttattgaaac agaagaaggg aaaaaagtag cagaagttac attgaccgat gcaactcctg
     3661 ctgacggtta tcgtattcga ttaactccta aatatgatta accttttggt gggtgtggat
     3721 cgtttccgtg actatcacgg ctttgaattt ttccatctct gccatgaata aatagctcag
     3781 atccttgatt tttagaaatc tctctagcga tttttactgc ttctgatttt gtattagtat
     3841 gtgcagtcgc tttagaattt ccagcacctt tgacattcca accaccattg gaattaggta
     3901 caacatgttg attttttccc atagttttca cctccatttc tatagaaata ttttatcaaa
     3961 tagaaatgga gaaattcaat aaacgaaagg agaagtgata tggcatatac cttgcaacaa
     4021 gaacatcaaa ttctcggttt gattaaacaa cgcaggaaac aattacaaga tgaccgtgca
     4081 gcgcttagaa aagccgatga gctatcagat aggcaagctg aactaattgc ttctgaactt
     4141 gaggatttga gaatgctaga aataaaaaat agggagatta gattatgaag aagacagaca
     4201 cactttttat aggattcatt ttggggttat tagtgattgt agcgcaccaa agtattatcg
     4261 ggggaagctt gttcgcagca ttgatggttt taatcaatct gcttgattca aaagaaagga
     4321 gcaactatgg cacgagaaga agcgctaaaa atcggtaaag tgattgctga taatcggtgg
     4381 ggaaatagcc gccctattat tttaagcaag caacatatcg aaaagcaaaa agcatggcaa
     4441 caaataaaaa agtgactctg ccagccagca aagagtcaca tacaaattta taaaactagg
     4501 agaattatat cacatgaata agaaaattga aaatcttatc gaagaattga aacgtgaatg
     4561 ccaaaagcaa ggtgtttcta ttatttgtac agcccaaaaa gaaggggaac ttaaaagtct
     4621 cgtttatggt gagacaacag aaattttact ttgtcttgct atgcaagaag aacatttaga
     4681 tgaaaatctc ccattgtcag cacatattat gcgtagaatt gctgtggatg cttacgaaca
     4741 agcgaaaaat gaagaagaaa atcaaccttc aaatcatact tttgttatta ataacaagga
     4801 agatttagct gatgtgatga ctcgtattct caagggggaa tttcaatgat gaatgaaaaa
     4861 acaattgatc tactcattat tttatttttc acgttagtga ttgtagcgaa aagttatgta
     4921 atctttggct tgttattcgc aattaccatg cttgtgcttt gcgtgttagc aagcagaaaa
     4981 gaggttaaac atgaacgagt tagcaaatct tgacaactat ttaactgatc ctgattatgc
     5041 taaaccacca tatgaagcac caattgatga ggaggatgaa gatgagtaaa tctaccttag
     5101 aaatgagcca tcaagaatgg cttgaagacc gtaagaaagg catcggaggt tcggatgttg
     5161 gaacaatttt aggattgaat aaatggaaat ctccttatca actatggcta gaaaaaacag
     5221 gacaagtagt acttgaagaa tcaggaagtg agcccgctta ttggggtaat gttttagaag
     5281 aagtggttgc taaagagttt caggaacgta caggcaaaaa agtacgcaga agaaaccaag
     5341 tatttgaaca tccattacat ccatttttaa gagcaaatat tgatcgggaa gtagtgggag
     5401 aaaatgccat tctggaatgc aaaacagcca atcaatttct cggtaaagaa tgggaaggcg
     5461 aagaggtacc gcttagctat ctctgtcaag ttcaacatta catgaacgtt ctaaacaaag
     5521 actattgtta catcgctgtc ttaatcggtg gtcaaaaatt tatctggaag cggattgaac
     5581 gagatcaaga gctgatcgat acaatcactg aacaattagt agagttttgg gaaacaaacg
     5641 ttcttggagg tatcgagcca attattgatg gtagtcaagc gacagctgat ttcttgaaag
     5701 agaagtatgc agatgttgaa gacgttcaaa cgacgttacc aattcatttc gatgaactag
     5761 ttgaacagaa aaacgaactc aaacggacta agaaagaaat tgaatcagct atccgtcaag
     5821 tagacaacga gattatcagc gagctaggta aacgtgaagc cagtatcggt atcactcaaa
     5881 aaaacatcat cagttggaaa tttgtccgta cgagacgtat gaactcgaag aaactagcag
     5941 agaaatatcc agatgtcgca aatgatgaag agatttataa cgttactgaa tcaagaaggc
     6001 taaccgaaag ggagatcaaa taatatggca acaaatgaat cgttaaaaaa tcaattggca
     6061 gcaaagccac agaaacaagt tgcaccaggt caattaggac ttaaagcttt gatgaataca
     6121 ccaacaatga gaaagaagtt cgaagaggtg cttcatgaca atgctaatgc ttttatgtcg
     6181 aatgttatga ctcttgtatc taatgacagt tatcttgcag atagtgaacc gatgtctatc
     6241 atgagtggtg cgttaactgc tgcaacatta aatcttgggc tagataagaa tttaggttat
     6301 gcatatttag ttccattcaa tagtaaaaac aagcaaacag gaaaatggga aaagaaagct
     6361 caattcatgc ttggctataa aggatatatc caattagccc aacgatcagg taaatacaaa
     6421 gcattaaatg tgatcgaagt ttacgaagga gaactaaaaa gctggaaccg actgacagaa
     6481 gagtttgagt ttgatccaaa tggtagaacg tctgatgaag tcattggata tgttggctat
     6541 ttcgagttac tgaatggatt caaaaaaact gtctattgga ccaaacaaga aatcgaagct
     6601 catcggattg ctaacaataa agatcgcgat aagacaaagt taagtggtgt gtgggcatct
     6661 gattacaatg caatggcacg aaaaactgtt ttgagaaatc ttctttctaa atggggaatc
     6721 ttgtccatcg aaatgcaaga agccaccaca tcggatgaga gagtccaaag ggttcaagaa
     6781 gacggcagca ttattgctga aacagaagtt gaagaagata ttcctgaaag aaaagaagca
     6841 gaggttatat ctgaagaaaa tgaagatgta caaactggat tatttgatgc atctaatccg
     6901 ccgttaaaca aataatgagg gagctttctc ccttgctttt ctagaggaga aatacgaatg
     6961 aacacaggat atgtcaaatt acatcgaaaa gtgatgaatt cattcgtttg gaccaatcct
     7021 tatatgtata aattatggaa cttgtgtttg atgaaagcga gtcatgagaa tcgcaagata
     7081 ctttttaatg gaaaagagat acaagtgaac agcggagaat tcgtcacagg gcgcgatgct
     7141 atcacatctg agatgaacga aggcgtgaaa cgtgaacatc aagtgaacag cggttctgta
     7201 tggagatggc taaaacaatt tgaaaaaaac ggaatgttga acatcaaatc aactacgaaa
     7261 tacagcgtta tatcaataaa aaactggtct ttgtaccaaa gcagtgaaca acaaatgaac
     7321 atcaaacgca caacaagtga acaacaagtg cacacaaaca agaatgaaaa gaattataag
     7381 aatgaaaaga ataataaaac atcatcgtcg caaccacgca aaaagcgtgt ttacgacacc
     7441 gactcagttt actacattct cgcggaggag ttattcaaac agatttgtca gaatcaggaa
     7501 atcaaaaagc cgaatctgca aagttgggca gatgacattc ggaaaatgat cgagatcgac
     7561 aagcggaccg aaaaccaggt acggggaatg attgaatgga gtcagcacaa tgtgttttgg
     7621 gcatcgaata ttttatctgc taaaaaattg cgagaaaaat acgacacaat ggcagcgcaa
     7681 gcaaatcgtg attataaaac aaaacaaact aaaacgcttg aatacgagaa atttagcaca
     7741 gatgagttgc ctatttgaga ggaggcgtag gcatggaaac tgttggggaa atcatggaaa
     7801 agctgataca gaaagtgctt gtccaacgtg gcgaatgtcc tgaatgcgga cagcctttgt
     7861 atggatggcg tacgaagaac cctgatggct cagaacgttg taagccaacc tgtatgcaat
     7921 gtgggtataa agcattgcga gttcaggaag acttacaaac agaacgaatt tacaacgaga
     7981 gcctgaaagc aagagcaatc aattttttca aaggtggttc tgttgtgcct aatcaagcgt
     8041 tgtttgattg cacattgcag aattatcaaa ttgtcgatca agaaacaaga caagcggttg
     8101 aagtaaccaa acgctttgtt aattcagtct tgttaggaaa tccaagtcac cttgttttaa
     8161 ctggaaaaca aggaacaggt aaaagtcacc tagcgatggc agcggcttgg gaagtcttga
     8221 agcgatcaaa ctacgataaa aaaatcttat ttatcgggtt acaggaaatg ctggatcaaa
     8281 tcaaattttc gtacaacaat cctgaactca gaaaaacgat tgagggatcg ttgattgcag
     8341 atatcaaaac agcggattta gtcatcattg atgatatcgg ttcagaacta ggaaaagatg
     8401 catcagatag tcgagcgttt ggcataaaca cgctaaattc gttcttggat gcacgacaga
     8461 acctagcaac gattatcaca acgaacttgc ttggtgaaga actgaaaaaa gcttacggta
     8521 cgagaacaat atcaagaatg tttgtcaact ctgatggatt tacgatggta ttttctcaaa
     8581 cagcagacaa gcgcataaaa ccagtcaaag gagcgatcgc atgaatttga ctaaacaaga
     8641 aaaaagaatc tgtcgtcaga taatgttgca aattataggt gatcgtgaca tggacgaatt
     8701 atctcaacaa gagagtcgaa tggttcggaa gataagtaag ctaattattt atcgggatac
     8761 agaaagattt ctcactgttt taggtaacgt ctacgagaat ccagagttat tggaggtaga
     8821 gtaattgcca aaaatattag atgcatgttg cggtagtaga ttgttctggt ttgataagaa
     8881 caattctgac gtaacattta tggattgtcg tcagcagtat gaagaattat caacaggtca
     8941 tgtgatcaat gttgatccag atgtggtcgc agactttcgc gatatgcctt ttgaagatga
     9001 tgtgttcgat atggttgtat ttgacccgcc acacttaaga catgtcggcg aaaactcatg
     9061 gcttgccaaa aaatatggaa aattagacga actttggcca gaagacatca ggcaaggttt
     9121 tgcagagtgt atgcgagttt tacgaccttc aggaacatta atttttaagt ggaacgagga
     9181 acagatacca ctttctgatg tgttagaggc tattggagaa cagccattgt ttggtaataa
     9241 acgaagcaaa acacattggc ttgtgtttat gaaaaaattc agctaacgga ggaaacaaag
     9301 gaggaaaagt aatgaagatt gtattaaata aatgttttgg tggctttggg ttgagccatg
     9361 aagcaaaaat ggaaattttt aaaagaaaaa atattgaagt attcccatac atcaataact
     9421 ttagctatga ctcagatgat gaatacacga gatacacagg ccaaaagcta ggttcgatgg
     9481 attttatcta ctatttcaaa aaagacccga aaatcgacaa agttacagga atttatagcg
     9541 aaattgaccg actgtacgga attgctgatg attccagttt ttcaagtgat tcaaacagag
     9601 gtgataagga cctcgttgct gttgtcgaaa aactaggaag tgaggccagt ggaccatatg
     9661 caagtcttaa agtcgttgat atacccgatg gggctgagtg ggaaataagt gattatgacg
     9721 gcgttgaaac tgcacattat ggttttcaaa caggtagtat ttagtccact aatgacaact
     9781 aaagaggagg cagaaggatg agtgaagatg aatactttga acagtagtct attaacgaca
     9841 gagattttta actggaaagg ggtgtagtca tggacgcatc ggaagtagta aataaaatta
     9901 atagtctcaa agaggttttc ggagacgtcg aagtagtgat aaacgcacaa ggctatgaca
     9961 acgaattttt taagcagatt accgacatta gcattcagca aggaatggaa gacgaagacg
    10021 gaaactttat cgatgaagta gccattttag tgacttgcga gtaagtaatt gacagctaaa
    10081 gaggaggaag cggaatgaaa ctaaaagacg gattttactc cagcggccac ggcatcggcg
    10141 gtttaatgct agatatgccg acaaagaatc ctaaaacacg taagaaacca aaattcaaag
    10201 tcggtgacat ggttcgctgc gaagcagaag gattcatcta tccatttcgt ggatatgtag
    10261 aacacgtcta taatcactca gcaatcattc gcattgaaaa cacgatggaa tgtgataagt
    10321 ggttagcgaa aagcaaagag aatttagcag tggtgagatt ggtggacatg gaagttataa
    10381 aatcttaatt ttgctttttt acaactatcc tacaacaatg agcgttattc cacaactgga
    10441 aggagaagag gcaattgtga acattttaga gaatatagat attaagcaaa caaggaaaaa
    10501 tgctagacga ttactaaaaa gatacagaaa tttagaacgt ttggtcggac cagtgaaaat
    10561 agacttttcc gtgatgactg ttaccaaaaa tttgaaattc acaattgaca gtcaaaacga
    10621 agaaatcatt gaagcgataa gtactcgaga ttcggttatc gaagcattaa cacggctaag
    10681 tagaatccat ttccaggtac tttattatag ttattgtttt cctaataaga tgtcaatgta
    10741 tcaaatagga gaaaaattag gatattccga tagaactatc gagagaatga aggcagtagc
    10801 tttggttgaa tttgctgagg cgtataaatc aggagaactc atttcacgta caaaataaaa
    10861 aaagtcggat tcctccgact atgaataata tttccgacat aagtattata tcataattgg
    10921 gggaatcaga ggatggtact tttcgatgta aagaaatatg agacaccaag cgcgaaagat
    10981 gttgatatgg aacgcacaaa acataatgtc gctgtgtttc tttcagcata tctatcagct
    11041 agatgtagag tagggcaaca tcgagaacca aaagtgacag catcttattc cttggttcca
    11101 ccttctacag ctgatcatat atttgaagca gaaagaatgc tgatcgataa agaagaagca
    11161 caggaagaat ttgagtatct gcataaattg tttgttcgag gctattcagc gatacagcat
    11221 ccgcataagc ctgatgtgac tgaaaggcgc aagaagatat tctatgatcg ttatatcaat
    11281 ggtctgccca tttatgtaac tgctcaaagg aataatacta gcgaagaatc ggttaaagta
    11341 gaatcaaaca gaattatcat ccaatttgct tcatcgttag aactggttgc tttcaagtag
    11401 ccagttttta cactttttat acccttttat taccaatttg gtttccattt tatacctttt
    11461 ttataccaat cacttaccta ttcaacgttg tattatgata gtgtcgaaaa attaggaaac
    11521 aggatcgaca aaataaaatg taagggagga aatctccctc atcgtttaat taagcttcga
    11581 taggcagcaa cggaaatatt aagaataagg atgtgaattt caactccttc taaattgttc
    11641 ttattatcta tcatccgttg ctgtctattg tttttttaat tattcacacg ataactaaag
    11701 gtaagtgaag agaaatgatt ccattaataa tttcaatttt tgcgctttgt cttaatgtat
    11761 atatgattgg atttaaaaat gggcaaaata aaaaatagta gcagccaaga ataattttat
    11821 agtgtcactg tggcggaaag ggtagacgct aagcatgtgt gctaggtcaa tgcttcggca
    11881 accatgcaag gttcgattcc ttgccagtga ctttggcaac cgaggcatcg gcggtttaaa
    11941 aatatagggg tgcgcaattt cgtacgcgtt ttgtgcatcg tgtaggttgc tattacataa
    12001 ctggttaggt tagattgaga tttgggattc ggtacaaatg aatcgtcaaa tgtctcaagc
    12061 acaggatcgg aaacgtccct gcctgtgcat tacatattag atcactcttt gagtggtctt
    12121 tttctttaca taaaggaggc tacataatga gaaactactg gtatgtatcg ctaactaatg
    12181 aatatcctcg aaccattgat gattgttcag tgcgtgttgt gcgttctgta caaatcaaag
    12241 ggaagtactc tattgtcgaa atggggagag aagcagaacc atgtgagatt gatgcgtgca
    12301 agctcgttta ttgcggtcat ggtttctatg atgaaccaaa cattcaaaat aatattaaca
    12361 agaatttgag ggattagaat gcaagaaatg gcttaaaaat ctccaatcag gacaaatcaa
    12421 gttagacaaa gtttccgatt taaagatatt gattgaagct gatttaatgc taaaagatat
    12481 tgaaaattag aaaacaaaac tcaacctaaa cagaatgtga ggtggtgtgt attgaatggc
    12541 aagacaacgt gatccaagac gtgatgaagc caaaagaatt tggttagaat ccaacggaga
    12601 aaagcagtta aaggaaattg catctgaatt aaatgtttca gattctcagg ttagaaaatg
    12661 gaaatcgcaa gacaaatgga gcgctgaatt gattagtaac gttaccaatg gcaaaagtaa
    12721 cgttactaat caaggtggcg ctcctattgg taatcaaaat gctaaaggta acaaaggaaa
    12781 tagccgagct tctccgccag tgggtaataa aaacgctttg aaaacaggtg agtatgaaac
    12841 aatatttttt gacacgttaa ccgataatga gaaggacatc tattctagtt tgaatgatga
    12901 tccttctttt gctttgtccg aagaaatacg acttcttaaa ataagacaac ttcgaatgat
    12961 gaaaagaatc caacaagctg aagctggact aaatgatgaa gaagtcgaac gattgcagca
    13021 gctaagaaag attaaaactc cgattgaaaa aaatggtaaa aagctagaaa tcaagcgtga
    13081 ggttatgcaa gatgtgcaga ttagcagaaa aaaacatcgc aaaattgatg atattctttc
    13141 aattgaagat tcattgactc ggattagcaa ccagttagct aaagccatca agcaaatgaa
    13201 tgaactttat atgaatgaat acagaactga tttaattaaa gctcagactg ataagatcca
    13261 agctgagaca aatgaaattg gcggaaataa ttcaggtgaa gaaatagaag aatggaaaca
    13321 ggcagtttta aatgccgcaa acaaacgggc ggtgaaagaa aatgaataat gaatttattc
    13381 cttttgctga tattggttct gccattgatt attactatga taaaccagta gctttttgcc
    13441 aagatatttt gcatttgaat cctgatgaat ggcaagaaaa tgttttaaat gatttagctg
    13501 aattttcaaa ggtttctgtt cgttctggtc aaggagttgg aaaaacagca ttagaagcag
    13561 gagcaatact ttggttctta acgtgtcgac cctacgctaa agtaatagca acagctccga
    13621 caatgaagca actttacgat gtactttggg cagaggtagc taaatggtta aatgatagct
    13681 tgatcaaaaa cttactgaag tggacaaaga ccaaaattta tatggttggt gattcagagc
    13741 gttggtttgc tacggctaga acagcgacta aaccagaaag tatgcaaggt tttcacgagg
    13801 accatatgtt gattgtggta gatgaagctt ctggtgtgtc tgatccaatt atggaagcta
    13861 ttcttggtac gctatcaggt tttgataata agctgttgat gtgtggaaac cccaataata
    13921 ttgaaggtgt cttttatgat tcccataatt cagaccgtga taaatacaga gttcataaag
    13981 tatcaagcta tgatagtaaa cgtacaaaca aagacaatat agaaatgatt cttaaaaaat
    14041 atggaaaaga aagtgatgtt gctcgtgtcc gtatttttgg agaatttccg aaaggtgcgt
    14101 tggattcatt tatcagtctt gaaacagttg aattggctac agaaaaacaa attagtgatt
    14161 ctttagtcaa taaaacaaag gttgctcata ttggtgtcga cgtagctcga tatggtgatg
    14221 attctacgat tctctttcct agaattgcta ccagggcatt ggagtatgag aagtattcaa
    14281 aacgtagcac catggaaaca acaggatatg tcatcaacat ggccaagaat ctaatgagtc
    14341 aatatccgag tattgataaa gtgatgatta aagtcgatga cactggtgtc ggaggtggtg
    14401 taaccgaccg cctagaagaa cttatagaag acaaacatta tccttttgag gtgtttggag
    14461 tgaataacgg ttcaacatca gaagacgatt tttacgataa tttaggtact caactatggg
    14521 gaaacatcaa ggaaatgtta gaagaaaata tgacagcaaa tcttaacgga gaacagcctg
    14581 ttattgaatt gccttctgat agttcgttaa tcaaagaatt aagtactcgc aaattcaaaa
    14641 tgacaagtag aagtcgtata cgtttagaaa gtaaagatga tatgaaaaag cgaaatattg
    14701 gtagtcccga tattgctgac gcactggctt tagcgtttta tgagccacca agtcactatc
    14761 aatttattca attttaggag gtgagctttt gattagtaca gtattatctt tagagagata
    14821 taagaagcta cgtgttaaat atgcaacaca aattgaagat ggaatgtttg atccgaatgg
    14881 ttttatagaa gatatgaaac cattttttgc tgatcgcgaa agaaaatatc tagcttatac
    14941 tagcgaaaag aatgaaatag ataatagacc aaagcctaac actgatattg taaaagttaa
    15001 taataaactt catgctggta tgtattcaat tgtcgtagac caagcagtca atcattttac
    15061 tggtatacct atcaaatggg attacgatgt atcggaacaa aaaagaacac tcattcaaag
    15121 attaaaagat aaattcttaa aaaatgatat agaacttccg acagttccag aagcttttaa
    15181 caaattaaca agcaatcttg attccatgag attcgcaatg cttgattctg aaactgcaac
    15241 ttttcaagga gcttgtggag tagctttccg attgctagag cctgtggaag aagatgatgg
    15301 ttggaagtta agagcaagta atattgaacc ttggagagca gaaagatatg gaaatgccgg
    15361 aatctatatc aaagaaaagt atgactctta ccagaaaaaa ttttttcaag aaatgaaagt
    15421 tatgacaaga aataaaattc tgacatatgc ttgctatggt gatttgaatt ttgttacaag
    15481 cggaacgttc aaaaaaattg atgagaccga taaccctttg gggacgatta ccttggcaga
    15541 atttaaaaat aatacgaatc gttattgtga ttttgaagta gctgaggaaa ttggagatgc
    15601 aattgatcgt gctttgtctg atcaacaaaa cgaaatcgaa caatttaagc ttgcgtacat
    15661 gcttgttact ggcacaacaa tgagcaaagg cactgctaaa gaaatgatga atcagctagg
    15721 gattatcaac ttaaaagccc ctactgcaaa agctgaatat gtcacaaaaa atttagcaaa
    15781 agatttcaat gaatatcata tggatctatt gaaaaaacag ttttacacca tttgtaaagc
    15841 aatcgatttt aacgatgagg tgtttaaatc aaacagttct ggagaagctc gcaagtggca
    15901 aatcattagc ctagaagcga aaacaaatac taaagagcaa tattttagag aaggattgaa
    15961 agaatgcgca gaaacaattg ctgcttttct taagtttcat gacaaagtag aaattgagcc
    16021 tgaaaaaatt atttttactt tctctagatc tttgccaact gatttaagtt atttagctga
    16081 agctttacct aaacttgcac catacgtatc caaacgaact attcagagcc aaattccatt
    16141 tgtaacagat gttgattatg aaaatgaaat gatggaattg gaaagtggaa gtgcttatcc
    16201 agatagtgaa tacaattttg gcggaggtgg caatagtgac gatagaaacg aagtattgga
    16261 ccaaacgtcg agaactggag gatcaagcaa ggctcaaaca agaaaatcag acacttaaaa
    16321 aattaactag tgtatttcct gaagcactga aagagataca agcaaaacta ttatcacaag
    16381 ctgacttaca caatatcact tatccagaaa tgatggagtt ttacagtaca agtaatcaga
    16441 aaaaatatcg tgaatatgtg gaaaaaaatt ataagtcatt aaaaatgtat gatgcaaaat
    16501 acaaagagtt tatcgatgaa ttttttccac catttgacta tgcaaaagtc aatcgcttat
    16561 tacaaatacg atcagatgta tttaaaattc ttgcagaata tgcgatggat gcagatgtga
    16621 atcaatattt ttctgatcgc ttagaggaaa ttcttcaaag aacatattct tctaatgcta
    16681 atgtttttgt tcaactttta aacgttgata taccaaatta tttaccagaa aatgaaatta
    16741 aacattattt gaactatcca tggtcaggaa agacattttc aagaagactt tggggaaata
    16801 tttcatcgct tgaacagaaa ctctctaatg ctattgtaaa aagtgttgct agtggagaag
    16861 gcgttataca cgcattaaac accatgagat tagactcaga aatttgtgac atgtttaagt
    16921 tagaagaatc aaagtataac aaagcgatag aaaatctcgt tcgaacggag tatgcaaaat
    16981 ttgcacaaga tggtattgaa aaatcatatt tagaaacagg tattgaggaa tacaacgtat
    17041 tgactgcaaa agatgagaga gtttgccgga tttgtggagg aaaggcaagt aagaatccct
    17101 ataaactgaa agatgctgtc ataggtgaaa atcgagcacc tttccatagt cgttgtagat
    17161 gtacggatgt tcctaattta ccaaaattag gaaaggatat tgatgaagaa tatgaccgtt
    17221 tatttggcga tttattagat gagtttgcac atgattcttt tggaattaat ttgaaacgga
    17281 ggaagtagaa tgaaagattt ttttgaagca gtactaacaa ttaatgtaaa tgctgatatt
    17341 gcagaagcct acaaaacagc tattgagtct gagaaccatc ctaatggctt gagagaccat
    17401 tggaatggca attatgccta cgtggttatt ggcgatcaaa ctgttaatta tcaagataat
    17461 actccagttg ataagaatac cgttaattta acgattcaat tattatctca ttcattacca
    17521 aatttaaaag aaacagttga ttggtatgaa aagatgggat gtattgttgt tagaactgac
    17581 tacaaagaag gaaagtctag taattaggct tttttatttt gtccgaaatg acgttaaact
    17641 agcgcaatac tgggcttggt tgaatggtgg ggcgcaacta ttaaaactca aagcaatgcg
    17701 gggcgtgaaa acgaatcgtg gggcgaaagg agaatgagca tgaaacacaa atcattaatg
    17761 ccaatgaatt tgcaatactt tgccgaaggt gacgatcaaa agttttcttt tgatgacttc
    17821 aaatcttttg tggaatccaa tgaagaagct caaaaattta ttcagtcaca atctcaaagt
    17881 gttgccgaca aacaattgga agcttggaaa caaaataact tagataaaat taaacaggat
    17941 accatcaagg aatatgagga atctaagaaa aacaagtcac ctgagcaaat tcaactggaa
    18001 aaactacaag ctgaatttga agcagaaaaa gcgttgcgtg tgacaagtga taataaagca
    18061 tttgttgcag aacaaattgc tggattagaa ctagatggag agttaaaaga gtctatttct
    18121 caatttatgc taaataatct tgttagttcg gatacagatt tcactaagaa tgctgttgaa
    18181 ggttttacaa gtgttttgaa tgcaattaat gagaaacatg cagatgcatt aaaagaacta
    18241 caaatgaagt ctgcatttgg tggaactcaa caatcgaata accaggttca gcagaacaat
    18301 gaaacattaa caaatccaga agaacaatta ggacaaattc ttcaacaatt taactaggag
    18361 agtgaaaaat tatgaaaaaa acatctttaa ataatttaga gtatttggat atttcaccag
    18421 cgattaatgc tatgcaagta ccaaatacac cttttttaag ctatttactt ggtgctggaa
    18481 aaacagagcc agcaaactcg acagaaatta aatggcgtga atatgatatc aacaacgatg
    18541 attcttctga aaaacttgag ggcggagaat atccagatgc tgaatcaggt cgaacttggt
    18601 ttaacaacta tactgaaatt tttagaaaat caacctctgt atctggtaca ttagatgcta
    18661 ttaatgtgaa tggagtcgga aatgaattaa ctaatcaagt agcactacgt ggtatggaaa
    18721 tgaaaattga tttgaaccga aaattgatta ctggtgtaaa agctgatgaa aatggttcta
    18781 aaggtcgtcg aatgaatggg attttgaact tgatcaattc agcaaataag gcagaaacag
    18841 ccactgcggg tgcagtaaca agaaaagata tcgatacttt atttaaattg atgtatgaaa
    18901 aaggttatat gggagaaaaa ctatgcttga tttctccaga tatgcaggag ttaatgactg
    18961 atgagttaga tggaaaatca acaaaaattg ttcagttcgg ggaaagagta acttttggat
    19021 tgcaaattgg aaatatcgtg tctaattacg gtacaggtat tgctctacta gaaccatcat
    19081 tgccaaaagg aacaattgcc gcaatcgata ctaattatgt gaaactacgt ccattacgtg
    19141 aatggagagc agaagaactt gcaaaaacaa cggattctag acgtatcggt cttgtaggtg
    19201 aatactctct tgaatacaat gcttcaaact ctggggcaat tttaaattta aagtctgaat
    19261 aaaagggagt tagtactccc ttttttgata ggaggaatta cagtggtaaa aaaagatgaa
    19321 actaaaaaag atgaagtcgt gaaatataga gtaggtaaaa ctaaaaattt tgttgggttt
    19381 gttcatccta aaactcgtag atttatcaca gcagattcaa ataacgaatt tatcatttct
    19441 atagatgata aagaagcaat tgcaattttg gaagatgcaa ttgatgttaa tgaaatttag
    19501 gaagtgatct gatggatgaa tcgctaaaaa cggaaatcat tgagtctaca aaagaagatt
    19561 ttccagattt gagtgaagaa cgcataacta atttattaga aataattttg ctagaaattg
    19621 aatcatacaa cacttgtaaa aatgatattt catgggaaaa gttaaaaagc gtgattagtg
    19681 aagtgttgta taaaataata aaaaatgaat cagaaaaaac agtatcttca gttagacgtg
    19741 gcgatacaac gattagttat gcttcaacaa caaatgatgt tagtgagtta cttctaggct
    19801 atggtgattt gatacgaaga gttattggtt gtggaggatt ggagtttttt taatgaatga
    19861 agcagatatt ttagaaacta cttatgaaga tagttgtatt attgaaagac tgacggacat
    19921 tgaagattct aatacaaata ttactattca agattacaaa aaagtatatg ataatcctat
    19981 ttcttgcgct ctttcacaag gtcaaatcga tggactagca gtcatagaag atggagagat
    20041 ggtaaatgtt tcaactgaca catataaatt atttgttcat cctaagatta aactaaaaaa
    20101 aggagatcga ataacaataa ctcaaaaggc cagtggctta attttttctc tatttgctac
    20161 taagcctttt tactatccta gtcattgtga agtgaatttg ataggaagtg agaaaaatgg
    20221 gtaatctcaa atatgaatca aatgcagaaa agatcattga gaattttaaa aatatgactg
    20281 taattgctca aaaagaagga atatccttcg ttaacgattc aatgaataaa gtcgttagtt
    20341 tagctaaacc attaactcct gtaaaatcag gtaatttaag gcgaggatat cgtgtagtaa
    20401 aagctagaaa actatcaagc ggtcgaattg ttggagaagt tataaacaat gaacattatt
    20461 ttaaatatgt agaagaaggt cataggacta aaaatggtgg ctttgtcaaa gggaaattca
    20521 tgttaactcg tgcaacgaat cttgcaaata tgtcttatat tcctcgaaga tttaaacaaa
    20581 tggcaataaa aatcgttaag aaaggaaagt aacatgaaag atgaaatcat tgctgcaatc
    20641 agtagcaaat taaaagaaat ctatcctgat gggacaatat atcttgattc agttatgcag
    20701 tcaactaaag atttttattt cgttttatca gtaatggaat ctggaactga aaatgtagga
    20761 attgatattc aaaatgtttc tttcttaatt gatattgcat tgattgataa taaccctaat
    20821 agaaatttaa ttaatgaatt agtctcacgt tgtgggactt tttttaatac gattacaatc
    20881 gatgagcaaa tattatttcc aaaagcctat ttacctgatg aagcagatgg tgttcaacat
    20941 attcgtttta cattagaatt tccacaatat attgaatgga gtgaaagata aatgggagaa
    21001 aaaagaagta aaaccggaat tatttctgtc gaaaaaccta cttggtttcc tttggaagat
    21061 gagacaggga attttccggt atatggtact gcgttgccaa tgggaacagc agtaagtatc
    21121 aaaccaacag ctaattatga aacaacacaa gattatgggg attcagtggt tcaagatcaa
    21181 tttacagctt ttggtggtgc agaagttgaa ctggaagcaa atggatatac tcataaagtt
    21241 ttatctacaa ttactggagg gaaaattgtt aaaggtggtg ccttgcgttc tggagaagat
    21301 attgcgcaag atggtgcgtt tgcatataga cgtaaaaaat cgaatgggaa ataccgttat
    21361 acggtctttt ataaaggaca gtttgctcta gattcagatg aaacatcaac gattgaagga
    21421 agtaaagtaa gttttactca tccaacttgg aagggttcat ttgtagatgt accaggactt
    21481 ggatatatgt attcagttga tgaagatgat gaaggcgtgg ataaagcaat gatcggaaat
    21541 tggtttacaa aagtagcaat tccaattgaa gaagcagaac tttcaggagg tacagaataa
    21601 tgtcaaaata tcaaacaacg attaaattaa cgaaaaaaga cgaagaaggt aaatatgagc
    21661 aagtacaatt taaatctgct gaatttttac caggaacagt tgtagaagat gctgcaggag
    21721 ttatggaaga aatgcaaaca gcgactgata agcaatcagt taaaaaagct ttaagtcgtg
    21781 cttattcatt tattgcagat actttatttg agggacaatt tactggtgaa gattattgca
    21841 aaggaattga tgctcgtgag attgcctcat tgacaggaaa attattgaag tctgttactg
    21901 caggttttga tgaaacttat acagagacga aaaaaaagta agtgaggcgc tcaagtcacc
    21961 ttcatttaag tattcgatta cttaccgaga attagatata aagacgcaat tactcgaagc
    22021 aggttggacg ttaccagaaa ttgaacgtac tgacttggat gagttaatgc gtctttttgc
    22081 ttttagagat gcggtaaaag agcatgaaga tgttgagtac tatgataatt tcactcaatt
    22141 ttaggaggtg atactttgaa taacgatgac ctaattctga agatgatact agatgaatct
    22201 ggttttactg ccggtatgaa taatgctgtc aaaaagttga actcttttga tgaaacaatc
    22261 gaaagaaaaa gtagaaatag tggcagttca ttaggtagta tttggaaaat atttgctgga
    22321 agttttctag ctagcggagt aactagaatc gtaggagctg gctttgatct aatcaagggt
    22381 tccataagtg gagcggttga tcgagtagat acgatgaata acgctctacg aaatttccaa
    22441 aatatgggat ttagtaattc agaaattatg aagaatatcg gaaagaatgg gcttttatct
    22501 caaggtattc aaggacttcc tactgctttg aatgatgcga taagtcatgt tcaacttctt
    22561 gcttcttcta caggtgattt aactcgttca actcaaatat ttaaagcttt aaatgatgga
    22621 attcttggtt tcggtggttc aactgatcaa gttaatgaag ctgttattca attatctcaa
    22681 agtttctcaa acggaaaagt agacgcacaa acttggaact caatgatcaa cgctcaactt
    22741 ggacctactc tttctgctat tgctaaaaag atgggaatta caatgggaga tctgaaagaa
    22801 ggtttatctc aaggtaagat ttctgttgaa gaattccaaa atcaattaat agaaatggat
    22861 accaaaggtg gcggaggact taaatcatta agtcaaatcg ctaaagattc tactaaggga
    22921 attaaaacct ctatacaaaa tgcaaaaaca gctgttacac gtggtgttgg tgaggtaata
    22981 gaaggattaa ataaagcatt agtagattca gatttaggtg gatttaaggg aattattgat
    23041 aaagtgggca gttcaatgga atcgttctta aaagtaattg ctgcaaatat tcctacagca
    23101 gtatcatttt taagtaattt atttaacgaa attcaaaaat ttggttctgc tttgaaattc
    23161 atgatgccct ttcttgttcc tgcagctacc gcttttggag cgttcatgtt tcaacttaaa
    23221 ggtataccag caataataaa aagcttcaat aattttaaga atgccataat tggcgttgga
    23281 aattcattaa agattatggg ggcaatagct gctgctaatc catttgtttt aattattggt
    23341 gcagtcgttg gtgcaatagc tgttttcggt tactttatgg caaccaatga agagcttaga
    23401 aacaaggtta tatctatttg gaatgatgtg aaagattccg taattggtgt attaaaaaat
    23461 ataaaggact ggggaattga tacttggaat tctgctaaag aaatggcatc aaatgcagtt
    23521 gagggtgtca aagatgcttg gtcaggaaca aaggaatggt tttctaacac ctggaaaggt
    23581 attaaggatg gggccacagg tttatttgat aaaacagtag agacttcaag aaatgcagtc
    23641 gatagtgtaa aaaatgcatg gtctaatatg aagaaatggt tttctgatac ttggcaaagt
    23701 ataaaagatt cagccagaga aaaatggaat ggaatcaaag gttctattat gtcagttgct
    23761 ggtccattga ttacaggtat aaagaatgca tttttacatg ttacttttta tctagagacc
    23821 ttatggaata atttagttga gattggtaaa aacgtctttg agattttaaa aaatgttata
    23881 cttgcgccgg ttttgtttat tacctccatg atttctggtg gatgggaaga aacaaaaaat
    23941 aatatgattg ctgtttggaa taatattaaa gaaagtgcca taaatatttg ggaatctata
    24001 aagaatatat ttgtaagtta ttttacaaat atttattttg ctgcactcaa tatttggaca
    24061 gggttcaagc ttacattgat aaatatttgg aatgaagtgg taaatcaagc taaatcgatt
    24121 tggttaaaca taaagtattt
//
LOCUS       DADLIO010000040        23829 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.040, whole genome shotgun sequence.
ACCESSION   DADLIO010000040 DADLIO010000000
VERSION     DADLIO010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23829
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.040"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(55..789)
                     /locus_tag="JOX41_001726"
     CDS             complement(55..789)
                     /locus_tag="JOX41_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HAY6449470.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1116..1526
                     /locus_tag="JOX41_001727"
     CDS             1116..1526
                     /locus_tag="JOX41_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HAY6449471.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1519..2220
                     /locus_tag="JOX41_001728"
     CDS             1519..2220
                     /locus_tag="JOX41_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HAY6449472.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2220..3806
                     /locus_tag="JOX41_001729"
     CDS             2220..3806
                     /locus_tag="JOX41_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAY6449473.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3825..4046
                     /locus_tag="JOX41_001730"
     CDS             3825..4046
                     /locus_tag="JOX41_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HAY6449474.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4043..4804
                     /locus_tag="JOX41_001731"
     CDS             4043..4804
                     /locus_tag="JOX41_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HAY6449475.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5184..5693
                     /locus_tag="JOX41_001732"
     CDS             5184..5693
                     /locus_tag="JOX41_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HAY6449476.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5768..6307)
                     /locus_tag="JOX41_001733"
     CDS             complement(5768..6307)
                     /locus_tag="JOX41_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HAY6449477.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6447..7058)
                     /gene="rpsD"
                     /locus_tag="JOX41_001734"
     CDS             complement(6447..7058)
                     /gene="rpsD"
                     /locus_tag="JOX41_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HAY6449478.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7374..8171
                     /locus_tag="JOX41_001735"
     CDS             7374..8171
                     /locus_tag="JOX41_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-nitrite transporter"
                     /protein_id="HAY6449479.1"
                     /translation="MNPVSPLFEKIDASIEKKANLFENSFSRYAVRAVLACLFLTLGT
                     AVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAELGTSNMLYMTVGVFRQRLA
                     LSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNFMLESIAVKLAKPSATILV
                     EGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLGYEHVIANFPAFTLTYFAS
                     HGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQSKSSYVD"
     gene            8199..8834
                     /locus_tag="JOX41_001736"
     CDS             8199..8834
                     /locus_tag="JOX41_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HAY6449480.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8854..9627
                     /locus_tag="JOX41_001737"
     CDS             8854..9627
                     /locus_tag="JOX41_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAY6449481.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10035..10832
                     /locus_tag="JOX41_001738"
     CDS             10035..10832
                     /locus_tag="JOX41_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HAY6449482.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10810..11223
                     /locus_tag="JOX41_001739"
     CDS             10810..11223
                     /locus_tag="JOX41_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449483.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11207..13852
                     /gene="mutS"
                     /locus_tag="JOX41_001740"
     CDS             11207..13852
                     /gene="mutS"
                     /locus_tag="JOX41_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAY6449484.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13870..15978
                     /gene="mutL"
                     /locus_tag="JOX41_001741"
     CDS             13870..15978
                     /gene="mutL"
                     /locus_tag="JOX41_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HAY6449485.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            16000..16560
                     /locus_tag="JOX41_001742"
     CDS             16000..16560
                     /locus_tag="JOX41_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HAY6449486.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16645..18633)
                     /gene="treP"
                     /locus_tag="JOX41_001743"
     CDS             complement(16645..18633)
                     /gene="treP"
                     /locus_tag="JOX41_001743"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HAY6449487.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18856..19569
                     /gene="treR"
                     /locus_tag="JOX41_001744"
     CDS             18856..19569
                     /gene="treR"
                     /locus_tag="JOX41_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HAY6449488.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19646..20092
                     /gene="msrB"
                     /locus_tag="JOX41_001745"
     CDS             19646..20092
                     /gene="msrB"
                     /locus_tag="JOX41_001745"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HAY6449489.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20262..20864
                     /gene="ruvA"
                     /locus_tag="JOX41_001746"
     CDS             20262..20864
                     /gene="ruvA"
                     /locus_tag="JOX41_001746"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HAY6449490.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20877..21878
                     /gene="ruvB"
                     /locus_tag="JOX41_001747"
     CDS             20877..21878
                     /gene="ruvB"
                     /locus_tag="JOX41_001747"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HAY6449491.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21907..22485
                     /locus_tag="JOX41_001748"
     CDS             21907..22485
                     /locus_tag="JOX41_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HAY6449492.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22537..23019
                     /locus_tag="JOX41_001749"
     CDS             22537..23019
                     /locus_tag="JOX41_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HAY6449493.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23136..23510
                     /locus_tag="JOX41_001750"
     CDS             23136..23510
                     /locus_tag="JOX41_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449494.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7782 a         4286 c         5117 g         6644 t
ORIGIN      
        1 ataaaaaaac ttggtacgca atcgctgtac caagtttttt tatttagctt ttgattaagc
       61 cataaataat aatttatata agaatactgc tacgacacca gcacagatag gtgctacaac
      121 tggtacccat gcatatcccc attgagaaga acctttatgt ttcaatggaa gaagtgcgtg
      181 tacaagacgt ggagcaaagt cgcgggctgg gtttagtcca ggacctgtag gaccaccaag
      241 tgaagcaact aatgtccata caaggaaacc aagtgctaag tgagctgtac caagattatc
      301 ttggaagaat ggtgcttttg taatacctag ggcaccaaag aataaaacga atgaaccaaa
      361 gaattcattg acgaaaccat tgaatttaga accaacgctg ttgattgttg agaatgtacc
      421 taacacatgg tttacgtctt ctgtttggtc gtagtaaggt ttgtaacaag ctactacgat
      481 caattgtcca atcgctgcac caatcaattg tgcaatgata taaggaacaa cttcagccca
      541 agggaataga ccattagatg ctaaagcaat tgtaaatgct gggttgatgt ggttaccgct
      601 gattccacca aaaatcattg ctggcatcat aaccccgaat ccatacccga cagcaatcag
      661 catccagtca ctgccatatc cttttgtacc ttttaaatct acgtttgcta cagcaccgtt
      721 acctagaacg attagtaatg ctgtaccaat catttccgcc gcaagacggg tcattagtga
      781 gtaatccata aatacctcca aaagttataa aaatgcaaaa aaaaaagaaa catcaacacg
      841 aaaagcatcg gtgcagtgtt tcgtgtcgga aggatttctg cagtcttaac aaatgtgaat
      901 aaaaaaatga attccattac ttataagaaa ccagaccaac agtaaaactc caactctttt
      961 taaaagttct ccacaaatca ccaagcttaa ctataaatat accaaaaaaa aaacgttttt
     1021 tttctcaaaa attgtatctt agaaacagca tgttttgaaa ctttcagaaa aggtttgtta
     1081 gtaaaatgaa agctatacgt aaggagtgtt gtttgatgaa attttttcaa gagtttttca
     1141 ttattatttt cttttctgta ttaggagaag gcatacggat ttttgctcat ttacctattc
     1201 ctggaagtat cttaggtatt ctttttttat ttttagcatt tgaaatgcat cttgttgatc
     1261 ctgaaaaaat cggagcaact ggtgattttt tattgaataa tctagccatt ttatttgttc
     1321 ctgctggtgt aggtttattg gaatattttg atgatattgc ttcgatatgg cctgttttac
     1381 tgggagcagt cgtcgtgtgt tccatcgtca cgatggttgc agcgggaaaa acggcagaag
     1441 gtgtagaagc tttgctgggc tatgtccgta agaaaaaagc agaaagggta tctgtaaacg
     1501 aaatggagga gaatcaaatt gactgagttt tttgtgaatc cattatttgg cttaagtttg
     1561 actttaggag tgtacgtatt atctgacaaa tttttgcgga aatataaact gcctgttttg
     1621 aatcctctcg tattatcgat tgttgttatt atcttatttt tgcatttttc tgggatcagc
     1681 tataaagact ataatatcgg gggcaatttt ttgactatgc tgattactcc tgcgacagtg
     1741 gcacttgcca tccctcttta taaaaacttc cgtttactga aagagaattt ttatcctgta
     1801 atggctgcga ttttagcagg aatagtcgca aattgcttgg ttagtgtagg gttcggttac
     1861 ttcttctctc ttcataaaga gatggtgatc tcattactac ctaaatctgt aacgacggct
     1921 atttctgtcg atttatctca tacgatgggc ggggtgaatg ccgtgacact tgctattgtt
     1981 gtctctacag gtatttttgg ttcgctgatc gccactcata ttttccgcct attcaagatc
     2041 gaaagtccag ttgctcgcgg tgtggcgtta ggaagtactt ctcatgctat tggtacagca
     2101 aaagcaatcg agattggtga aatagaagga atcatttccg gacttgcgat atgcgtcaac
     2161 ggaatattga ccgttttatt gctaccgtta ttctttcagc cttttgctgg cttgttttga
     2221 tgcgaaaacc actattttat gctacaataa ccaaaacgtt cgagcataaa aaaggaggga
     2281 aagacgtgta tttgtcttcc gagtatctta aacaatttga taaagatcta tattataaga
     2341 ttctcctcct agaaagtttt gaggatcaag cttggcatac cgctgcacaa ttagcgcaag
     2401 ttgttcagct ggatgcccgc agcgtgtcga aatacctgaa cgagctgtct aaaaactatc
     2461 agcagtttag cggtaagaca caccctttgt ttacaaaaaa tcaccgttct ggttataact
     2521 tttatgatac gctcgattca attgaacatg agcgtttttt gatctatctc gtgcaaagta
     2581 cgctgaaatt ccagttgctg cacgacattt tttttgaaga attccataca atgtaccaat
     2641 ttgcgcaaaa gcattacatt agtgaatcta ctgctcatcg aaaaatcaat gaatggaaac
     2701 agcaactgca aacttacgga attcggctgc aacgaggtac atatatcgct caaggcgaag
     2761 aagaaatcat tcgactttac ttgcatatga cattctggca gttgtttcga gggaaaatct
     2821 ggccatttga aacgatttct caaatggacg taaagaatat ggcagaacat atcatggctt
     2881 tttttaatgt tcgtctgaac gagatcaaaa aaagacgatt ggaatatatg ctaggtgcct
     2941 tttttttaag aaaatcacag aagcattatg ttgtattgaa tgagaaaaaa agacggctga
     3001 tttctgacaa tctgttgttc cagcgatttt gccaggtcat ggagccggta tttcctaatt
     3061 attttcaagt agaagacgag ttaggcgcat tatttcttgt actgatgact cgtgaagaat
     3121 attatagtga tcctaagata cggaagaaaa tttttgattt tcatcaacaa gcaaaaacac
     3181 cgccctttac agccctttca gaagcaaaag ccgctctttc tctttatcag gaagagcagg
     3241 ggctgccagc agaaaatcta accttcgagg cagaaaacta tttattcagc agtcattttt
     3301 tcgcctatct ttttcctaat gcgaaagaaa cgattgatgg caatagtagt gattttatta
     3361 atcatttagt tattgaaaac aaggaattga aacaatggct cgtacatttt tttgaaagta
     3421 gacacaaaca tcccaatcat ctggcattta aaaatcatgc gtttttgatg gggcggtatc
     3481 tgactgtgtt taaaacatta ggagccttta ctccacagct tccaaagatc acgatccttt
     3541 taatgacaga tttcccatta tttgaagagc aactgttaga ggagggatta cggacatttt
     3601 tccgtaatga gtatcagctg atttttctgc caacagatta tcgggggaga gaagttgatc
     3661 ttctgatttc gacaagtaaa gtccaccgca aaccatgggc ggatcttgac tattttattg
     3721 tgactgaaga actaaaatta attgattaca tccaactatc tcaaaaattt gaaatgattc
     3781 aaaaacaaaa actattaaaa caataacaaa gaaggagaaa aaagatgaca tttgaagaaa
     3841 ttttaccaga attgaaaaaa ggtgcaaaga ttattcgtaa aggatggagt ggatttgaac
     3901 tttatgttgt tctcgtatcc gatgatgaat ttgatggctg tccggtgacg ccgtacttat
     3961 tgatcaaaac aagtgacgaa ggtttttcca gcttcgctcc tacagtttgt gatattttag
     4021 cagatgattg ggcgatcgta gaatgaaaaa ccagtatcca gatctagcta aacaggttgt
     4081 atttatcaca ggagctgctt ctggaattgg tgctgcgcaa gcccgagcgt ttcttgaaca
     4141 agatgctttt gtatttggat tagatcaaaa gttcggtaaa atggaagaaa tttctttgcg
     4201 atttcctgaa acttttgcct acgcactagg tgatgttcga caaatgaaag aactccaaca
     4261 agcggtatcg aaatgccaaa atcattttgg tgaagttacg attttactga atacagcggg
     4321 gatattggat gcctacaaac ccttgatgga aactgacgaa tcgctgtggg atctgattta
     4381 tgagacgaat gtgaaaagca tgtatcagct gacaaaaatc atccttcctg atatgatccg
     4441 ccaaaaaagc ggaacgatca tcaatatggc ttcgattgct ggcttgattg ctggtggagg
     4501 tgggatcgct tatacaagcg cgaaacatgc gattgtcgga tttaccaaac aactcgctct
     4561 ggattacgca ggacagggta tccgagtaaa aggaattgct ccaggagcca tccaaacacc
     4621 aatgaatgcg gctgattttg aagggaaagg tgagatggca gagtgggtgg caaatgaaac
     4681 accagtcaag cgatgggcac agccggaaga agtagctgag ctgacgttat ttcttgcctc
     4741 tcctcaagca agctacatac aaggaacgat catcccaatc gacggcggat ggttgttaaa
     4801 ataaccttgt gtttttttca agcttctgta tgataaaact aaagagagaa acaacggttg
     4861 atgataaaaa aagtcgatga ctgttcccga cattcgatgc cgaacagcca gttcaaaaaa
     4921 ttctttttaa taatcgttaa tattcgaaac taagcggctt ttcacgacct cttgatataa
     4981 acgatattca aaagcttgca actgcggtaa caagtccagc caaatgaaaa atataaggag
     5041 ctatttttat ttgaccattc ttattacttg ttgcagggca gctttttcac taccttctgc
     5101 gacacttcag ttggaatttt cttcccatcc tttggtcgcg gtcattacca agataaaatt
     5161 atcttgcaaa ggagaaatag aacatggaaa aaaataatac ccgttcagcc aaacgctgga
     5221 caacgacaga tgtgactcgg atggcgctag tcactggttt atatgtggca gtgacgctgg
     5281 ttttgtctgt ctttagcttt ggagtgattc agattcgtct ctcggagatg ttcaactatc
     5341 tgtccttgta taacaaaaga tacatcgtcg cggtaacagc gggagtagct ttggctaata
     5401 ttgcttctcc tcttggactg atagatgttg cagtaggaag cgtcagcacg ctgcttgtat
     5461 tgcttatcaa ctataaaatc actagtcgca tcaaaaacat gaaaatcaaa atggccgtga
     5521 cagcatgcgt atttgctttt tccatgttta cagtagctgg tcagctaacg attttatatc
     5581 aactaccttt tttcttgaat tggtgggtga ttgctttagg agaattggca tcaatgattg
     5641 tcggtgggat aattatttat tggatcggta aaaaagtgga tttgtcaaaa taaagatctg
     5701 tttaatttaa aatagggcag catggaagag actgaatgtt gagtcttctt ccatgctgct
     5761 tttttgatta atttgtatga agaaatcgat ttagccgttt tttcatcaag ataccgatat
     5821 aagctgctcc agttgccttg attgcttccg gcagtaaaaa cggcagtagt ccactggcaa
     5881 atgcagttgt aaaagtaaga tcaccactta ttttcagcca gatcgttccg cagatcaatg
     5941 cagcaagaga gcccattaga ttggcaaaga ttgcatataa gtaatgagca tccgttcttt
     6001 cgatcatcca accagttatc cacgtttgta agagaaatcc aatcaaatat ccgccagttg
     6061 gcccaaataa aacagctata cctccagtca tccctgaaaa tacaggaaga ccaatcaagc
     6121 caagtaaaag ataaactcca acagatatca atcctagttt tcttccgaga aaagttgctg
     6181 ttaatccaat agcaaatgtt tgccctgtca aaggaaccaa accaaaagga atggtcatct
     6241 gagaaaggac agaaataatc gcggcaaatt ccgcagcaag tatcaattct ttcaatgttc
     6301 ggttcataac gccctctttt cgttaactta atatttttat ttggttaacg aaattgtaaa
     6361 acaaagtgat tactttgtaa atagaaaata taaaaaaaga ccagctatcc aatagatagc
     6421 ggtctttttc aagaaagctt ttgaaattat aagctttggt tgtagtattc aacgacaaga
     6481 gcttcgtcga tttctggata tagttcgtca cgttctggta aacgagtcaa tgaaccttcc
     6541 aatttttcag cgtcaaagct tacgaatgct gggcgtccaa cagttgcttc tacagcttct
     6601 tttactgtta cgatgttttg tgatttttca cgaactgaga tcacttgacc cacttctacg
     6661 tggtatgaag ggatatcaac gcgtttgcca tcaactaaaa tgtgaccatg gttaactaat
     6721 tgacgtgctt gacgacgagt cgttgcaagt cctaaacggt aaacaacatt gtctaaacgt
     6781 tgttctagta agatcatgaa gttaacacca tgtttacctt ctttgatttt gctagctttt
     6841 acgaacaagt tacggaattg acgttcgttc attccgtaca tgtgacgaag tttttgtttt
     6901 tcagttaatt gcatgccgta ttctgattgt ttgccacggc tattaggtcc atgttgacct
     6961 ggtgcgtaag ggcgacgtgc taattctttt cctgtgcctg acaatgagat gcctaagcga
     7021 cgagaaattt tccatgatgg tcctgtataa cgagacatta aaatttcctc caatgaatat
     7081 aagtttttgg agtaaaataa tccgttgaaa aattcataat catatagttt gttcttcaat
     7141 cttcaccttt gcagccgcgg ttacacaatc gaacccgaga cggggcaaca aactagggat
     7201 gagttattat ttttctgctg cattatttta cacaaattac agtatatgat agatcatcca
     7261 cgaatgtcaa gataattagt acataaaaac gctttacaaa cctaggctgt ctttataaaa
     7321 tgagagggta tgtgcaaatg gaaaaaagcg aaggaagttt aaggagaaaa tcaatgaatc
     7381 cggtatcacc attatttgag aaaatcgatg cttcaattga aaagaaggcg aatctttttg
     7441 aaaacagctt ttcacgttac gctgttcgag cggttctcgc ctgtttgttt ttgactttag
     7501 gaacggctgt ggcatttgcg atcgcgatga agggggaaga tatcgcgcat ggtctaggaa
     7561 agattttata cgcatttatg ttcagctggg gtctggtcat gattctatac atgaacgccg
     7621 aattaggaac atcgaatatg ctttatatga ccgtgggtgt ttttcggcag agacttgctt
     7681 taagtaaggc agccaagatt ctatttgcct gtattttttt caatatgatt ggcggtatat
     7741 tatgtggatt tctaatttct atgactacgc catttcaaga tttaacgttg gacaacttta
     7801 tgttagaatc aatagcagta aaactagcaa aaccttcagc aacgattttg gtggaaggga
     7861 tgtttgcgaa tatcgttgtc aataccgctg tactgatcag catgcggatg aaagaggatg
     7921 tcggaaaagt gatcacagtc gtattcatca ttttcatttt tgctttttta ggatatgaac
     7981 acgtgatagc gaattttcct gcctttacgc ttacttactt tgcttctcac ggacagatgg
     8041 atggaatgac agtcagcaat gtgttacata atttgttttt tgctttggca ggaaattata
     8101 ttggtggcgg tttagtaatg ggactgggat atgcttggct gaatcagtca aaatcatcct
     8161 atgtggacta aaaagtcgtt cattaaaggg gaagtgccat ggaagtttta gtttttccaa
     8221 aaaatgagga aaaagcgtta caaatggaaa agtacatgaa aaatcttttt tcctttgctg
     8281 gagtacctaa gccggaacgc gctcttttac aacaaccgtt actggatgag agcaaaaatt
     8341 tatctatttc tgaagtttta gcttttgttc attattatta tgaacaaatc gaaagagagt
     8401 atcagtatgt agcgatcgat ttagtccaga aaaacatcaa acggcttaca tttgaagact
     8461 tagtcgtatt gttgccacta gttcagaaaa aagaatggtg ggacagcatc gactcttgga
     8521 gaaaagtata cagcacatgg tgtaaagcct acccagagca gcgtgaagaa gtctttcaat
     8581 tgtttgaaaa aaaggaagat ttttggctac gtcgaatagc aatcacgttg caattaggtt
     8641 ataaacagca aacagacaca ggactattga tccgagcaat agacgaagat cgtcaaacaa
     8701 aggaattctt tatccaaaaa gcaattggtt gggcattacg cgattatagt aagaccgatg
     8761 ccgattgggt aaaaagacag ctgacaacag atttgagtaa gttagctgtt cgagaggcaa
     8821 gtaagtattt ataagaaagc gagacgacaa gagatgagac gcaaattatt tgcttttgat
     8881 attgatggaa cgttgttaga ttcaaacaaa caagctttag atagcacaag agaagcattg
     8941 gaaaaattac gcaaagccgg tcatctggtc acgattgcta cagggcggag ccgatttcat
     9001 gcgcaagaga tcattcgcga tcttgatttt acgaactaca ttttatgtaa tggagcggcc
     9061 ggttttttag accatgaaca agtatataag aatttactag atcgcgacca gttggatgcg
     9121 ttcgttcaag aagcgcatca tgagcagatc gatacagctt ttgtcagctt agacaatatc
     9181 aagcgttctt cttccaatga tgtaacggtg atggaagaag cgatgcattc tttcggtgct
     9241 gtcttgcctg aattagatca gttttttgca gaggaacaag aaatatacca agcgttagca
     9301 tttttcgatc aaacatatga tgggaagttc tcttcatatg ataaaattcg atttgtccgc
     9361 tggcatgaga acagtgtaga tgtcgtacct aaaaatggtt ctaaagcagc gacaattctg
     9421 cacttagcag aacaagtagg catccctcat gaagacatca tcagctttgg cgatggacaa
     9481 aacgaccgtg aaatgttgcg catgtcagga attgggatag ctatggggaa tgctgtgcca
     9541 gaagtacaag cagaagctaa gatggtcact gatacaaacg atcaggatgg aatttggaag
     9601 gcattgaaag agttaagcgt gatttaaaag aggttgtgaa aaagctgttc tgcatcaagt
     9661 aataagccca gccaaacaaa aatagctcct cctatttttc gtttttctgg gcttattacc
     9721 gcagatgcaa gctttcgaac accgtttaag gaagaggtcg tgacagaagt ggtcagtttc
     9781 aagaaataag aagggattta cgaaaattgc ttctcaaatt tttgtaaaat tacggcttat
     9841 ttctgaagaa gtagatgaaa caacgtttat tcgggaaatg ggactgtgac aagatgtttg
     9901 tcatagtccc atttttttat tttatttttc aaaactaaga aataccagga aagagttcct
     9961 tttgtttgac cttttctttc ttattgaaaa caactataat atagagtgat gttaaaagag
    10021 aagaggaatt tagtgtgcgg gtattgttta ttggtgatgt agtaggttca atgggacgag
    10081 agatgattac tgaatatctt cctagattga agaagaagta ccgtccgcaa gtaacgattg
    10141 taaatggtga gaatgccgct tctggacgtg gaatcacaga aaaaatctat aaaaaatttt
    10201 tgcaagacgg cgtagatgtc gtgacgatgg ggaatcatac gtgggacaac cgcggaatct
    10261 ttgagtttgt aaatgaagct aaaaagatgg ttcgtccggc aaattttccg gaagggacgc
    10321 ctggacaagg gatggtcttt gtcaaagtga accaagtcga actggcagtg atcaacatgc
    10381 aggctcgttc ttttatggtg gacttggatg atccttttcg taaaatgaat gagctggtag
    10441 aagaagccag aaaacgtacg ccgatcattt ttgtagattt tcatggagaa acaacaagtg
    10501 aaaaacaagc aatgggctgg tttttagatg ggaaagtttc agcagtggtc ggtacacata
    10561 cacacgttca gacaaatgat gcgcgaattt tgccaagagg aacagcgtat ctgacagacg
    10621 ttgggatgac aggtccctat gatggtattt tgggtatgcg cagagaacct gtaatcgaaa
    10681 agtttctgac tgcattacca aaacgttttg aagttgtgga acaaggccga tcgattttaa
    10741 gcggctgtat cttggaattg gatgatacga caggtcatgc aaaagaaatc cagctgattc
    10801 agatcaacga tgatcgaccg ttcatggagt agaaagagag gcagtttttt gcagcaggag
    10861 ccggaaattc aaaaagaagt aaggaaactg acaaaacttt taagagagaa tgaaacgatc
    10921 attcgctaca aagaacttga agaaaagatc cagcaaaacc agtatttagc tgagttgaga
    10981 gaaaaaatca aacaagcgca aaaagatgct gttcattttg cccactatga caaaccagca
    11041 gcagaaaaag aagcaatcaa acaagcggat caattcatgc aagaatttga tcagcatccg
    11101 cttgttgtag cttatagaaa acagctgttg gaagcagatg atctgcttca tcatttaaca
    11161 actatgatac aagaagaaat caatggacaa atagaggagg aaaaacatgc ctcaaaaaac
    11221 taaaaatact cctatgatgg aacaatatct aagcatcaag gcccaatacc aagatgcttt
    11281 tttgttctat cgtttaggag acttttatga actattttac gaagatgcga tcaaagcgtc
    11341 acagcttttg gaattaacgt tgacgagcag aaatcgaaat gcagaagaac ctattcctat
    11401 gtgcggtgta cctcaccatg cagcacaagg atatatcgat gccttgattg aaaaaggcta
    11461 taaagtagcg atttgcgagc aggtagaaga tccaaagacg actaaaggga tggtcaagcg
    11521 cgaagtgatc cagctagtca ctcctggtac agtcatggac agcaaaggat tgtcggcaaa
    11581 agacaacaat tttttaacag ctgtagttag tcaaggaaat gaatttggct ttgcttatgc
    11641 cgatttaagt acgggagaat tgaagacggc tcggttgcat gatgaagaag ctgttttaaa
    11701 tgaagcctct gcattgcaga caaaagaact cgtattaggc agtgagatca ctgataccct
    11761 tcgtgaacag ctaagcgggc gtttagggct agtcttttct caacaaaatg agatggaaga
    11821 aaacgcggaa tttagctttt tgacaagcga actagtcgat ccgctggaaa aagaagcaac
    11881 cggcaaacta ttgacttatt tatcggtgac acaaaagcgg agtttagctc atatccaaaa
    11941 agcagtagaa taccaaccag atcatttttt gaaaatggat tattattcaa aattcaacct
    12001 agaattaagc caatctattc ggactgggaa aaagcacggc actcttctat ggttgttaga
    12061 tgaaacaaaa acagcaatgg gtggccgttt actaaaacaa tggctagacc gtccgcttat
    12121 ccaggcaaaa caaattaaag caagacaaga aatggtcgct tctttgctag acagctattt
    12181 tgaacgtatc gatttgcagt cagcattaac gaaagtctat gatctggaac gcctagcagg
    12241 tcgagtagct ttcggtaatg tcaatgggcg agacttgatc cagctgaaaa cttctttaga
    12301 acaagtgcca atgatcagag ggttgattga aggaatcgat caaggtcaat ggcaaagtct
    12361 gctttcagaa atgcagccga tggaccatct cgtccaattg atcgaccaag ctatccaaga
    12421 tgatccgccg ttacaaataa cggaaggaaa catcatcaaa gatggattca atgagcagct
    12481 cgatatgtac cgttctgcta tgagaaacgg aaagaaatgg ttggcagaac ttgaagcaaa
    12541 agagcgtcaa gaaacaggaa tcaagaactt aaaaatcgga tttaaccgcg ttttcggtta
    12601 ttatatagaa attacaaaag caaatcttgg aaatgcagaa ctggagaagt atgaacgaaa
    12661 acaaacttta gcaaatgcag agcgtttcat cacaccagaa ctaaaagaat tggagacaca
    12721 aatcctcgaa gcagaagaaa aatctgttga tttagaatat cagttgtttt tagctgtgag
    12781 agaagaagtc aaaaaggcta tccagccgct acaagtactt gcaaaagcaa tcagtgcagt
    12841 agatgtgcta caaagttttg caacgatcag cgaacgctat cagtatgttc ggccagaact
    12901 tgtcagtgac aagcatcagc ttctgatcaa agacggacga catcctgtag tagaaaaagt
    12961 attaggacat caggaatata tccctaacag cgtagaaatg gcagaagacg aaatgatctt
    13021 gctgattaca ggaccgaata tgtctggtaa aagtacgtat atgcgacagt tggcattaac
    13081 tgttctgatg gcgcaaatgg gctgtttcgt tccggcaaaa caagcagttt tacctatttt
    13141 tgatcggatt tttacccgaa ttggtgcaag tgacgactta attgctggac aaagtacttt
    13201 tatggtagag atgatggaag ccaatcaagc cctgcgttat gctacgccaa acagtttgat
    13261 tttgtttgac gaactagggc gaggaacagc aacctatgac ggaatggcgt tggcccaagc
    13321 aatcatcgaa tatatccatc gtcatgtaca agcaaaaaca ctcttttcta ctcattatca
    13381 tgaactgacg gtacttgaga aagaacttcc gcagcttaaa aatgtccatg ttggagccgt
    13441 tgaaaaagac ggagaagttg tcttcttgca taaaatgatg gatggacctg cggataaaag
    13501 ctacggcata catgtggcaa agatcgcagg attgccttcc aatctactag aacgagcagc
    13561 agatatcctg catacgctag aaaatggcga taacggacac catactgttc cagctgaagt
    13621 agaagagaaa actaaaacag ccaaacagga gcaaataaaa ccacctgcag aaaaagtaaa
    13681 tcaagaccat atacaagacc gtgtaaaaga agaaaaccaa cagctttctt tattcagtga
    13741 attatccgaa aatgaaacag aagtcattga atcactgaag caaataaatt tactagaaat
    13801 gacgccaatg gatgcactaa acacattata tgaattacaa aaacaactgt aggaagaagg
    13861 cggatatcga tggccaaaat ccaagaatta tctgaacgtt tagctaatca gatcgctgcg
    13921 ggagaagtag tggagcgacc agcttccgtt gtgaaagaat tagtggaaaa tgcaattgac
    13981 gccggcagta ctcagattga tatcttagtt gaagaagcgg gactgcggac gatccaagtg
    14041 attgataacg gagaaggcat tttggcagac gacgtagaga atgccttcaa gcggcatgcg
    14101 acaagtaaga tccataatcg cgacgatctt tttcgcatac gaacgctggg ctttcgaggg
    14161 gaagctttgc caagtattgc ctctgtttct gaaatgactc tggaaacggc gaatcaggaa
    14221 gaaaaacaag gcacctatct gtcgctgaaa ggcggagaag ttattgagca tcgaccagca
    14281 ccactgcgtc aaggaacgaa gattaccgtc agcaatctgt ttttcaatac gccagcccgc
    14341 ttgaaatacg tgaaaacact gcacacagaa ttagcgaaca tcggggacat cgtcaatcga
    14401 ctggcattga gtcatccatc gattgctttt cgtttagtac atgatggaaa caaaatgctg
    14461 gcaactgctg gaaatggcga tctgaaacaa acaattgcgg gaatctacgg attatctacc
    14521 gcaaaaaaaa tgctgaaaat cgaaggaaaa gatctagatt ttgagttatt tggctatgtt
    14581 tcattgcctg aggtgactcg tgccagtagg aattacttat cgacgatcat caatggacgt
    14641 tttatcaaga acttttcctt gaataaagca atcgttgcag gttatgggtc aaaattaatg
    14701 gtcggtcgtt tccctattgc tgtattggaa atcaaaatgg acccgctttt agtagatgta
    14761 aatgttcatc cgacgaagca ggaagtccgg ctgtcgaagg aaaaagaact aacagagcta
    14821 attagtaacg ccattcaaaa agcattgtct caagaaaatc tgattccaag tgcagcggat
    14881 aatctacggt ttaagaaaaa agtacctgat cagcctaaaa cagaacaaat cgaaatcgat
    14941 ttgtcctacg cttttgaaga agaaaaacct aaaaagccaa gtagtttgaa ttttgatcga
    15001 gagacaggta cctttttcgt agaagaacta aagaacacat ttgttgacag aattgttgat
    15061 aagtctgtgg aaaatgttga aaactattct ggtttttctg aagaaaacac cacttatcca
    15121 gaaaaaacag cgaaaacggt ggataagttt ggtgaaaatg ttgataactt tgtagaaaaa
    15181 acagtggaaa aatctgaaaa gaaagaattt cccattgtgg ataacatgga gaaaacaaat
    15241 gaagaacaag cagataaatc cgtagaagag gatgaaaaga tttacgagga agaattgaca
    15301 ctccatcctg aatttgattt cactcaagga aacgacaaaa cattagaaca agccatcaag
    15361 aaattagaaa cggaaaaacc agtacaacgt tttcctcagt tggaatattt tggacagatg
    15421 cacggaacgt atctttttgc ccaaagtagc gatgggttgt acatcattga tcagcatgct
    15481 gcccaagagc gcattaagta tgaatatttc cgggaaaaaa ttggggaagt atctgatgat
    15541 ctgcaagaat tgcttgttcc atttgtgtta gactatccaa acagtgatgc tttgaaatta
    15601 aaagagcaaa aacacttgct agaagatgca gggatttatt tagaagaatt tggtcaaaac
    15661 agctttattg tacgggccca tcctacttgg tatcccaatg gagaagaaga atcgattatt
    15721 cgggagatga tcgatatgct gctgacaact ggaagtgtga gtgtaaaaaa attccgtgaa
    15781 gcaacagcaa tcatgatgag ttgcaaacga tcgattaaag ccaaccatta tttgaatgaa
    15841 gcacaagcac gtgtgctgct gaaggatctg gcacgatgcg aaaatccttt caattgtccc
    15901 catggccgtc cagtattgat tcactttacc aattcggata tggaaaggat gttcaaacga
    15961 atccaagacc cgcattaagt caaagagaag agggaaaaca tgaagattgt attagcatcc
    16021 caatcaccaa gaagaaaaga gttattggct catatcgttt cagaattcga gattgaacct
    16081 gctgatatcg atgaaacgcc atttccagac gaacagcccg tcgattatgt tcgtagaatg
    16141 gctgaagaaa aagcacgaac tgtctgggaa caagatgaaa aagaagacca tttagtgatt
    16201 gccagtgaca cgactgttgt tctcaatcaa gagatcatgg gtaaaccaga agatctggct
    16261 gaggctgaat tcatgctgaa aaaactaagc ggggaaacac atactgtata tacagctgtt
    16321 gttttaaaaa caaaggaacg agaagaacgg atactagcag aagcacatgt cactttttat
    16381 cctttgacag acgaagagat caaacgctac ttggagacgg gggattatgc ggataaggca
    16441 ggggcatacg gcatccaaaa tgctgcgagt gtattcgtca aagaaatttc tggagattat
    16501 tacagtatcg taggatttcc gattggtgct gtcaatcagg cactgaaaac attcatttaa
    16561 acaaaaaagc ggactatctg attttcgatt gaaaatccat gatagcccgt tttttttatt
    16621 gaaaagatta cttatctact ctgactaaga ttttacttca gctttaccga ctgcttcgcc
    16681 cgggcgaaca agtcctgatt ggtcaagaga aagtcctgca actttttcat tattggtcaa
    16741 agcaacaata atgtcagttt tcttgccagc ttgttctatt tctggcaaat ccatttcagc
    16801 aatcagggtc tctggtgtga caaggtatcc ttctttcacg aatacattga aaggaacacc
    16861 ctttagttca acagtatcta atcccatgtg aacaagtact tccagcccct cattagaaag
    16921 aataccaatg gcatgttttg tttcaaagac actcgtcact ttaccgttta ctggtgcata
    16981 gactttgccg tttgacggtt cgacagcata accgtcaccc atcatttttt gtgagaaaac
    17041 tgggtcattt acttcagtta tttccttgat ggtccctgca gcgactgcga ataatgtttc
    17101 ttttgttgca actgccgtac cagttgctga aacaggttcg aaagactgtg gcgttgctgt
    17161 tgcgccattt gctgtttgaa gttgtacatc agcagcattt tcaggaacag caggatcaat
    17221 cttattcaaa attccctgac gtctaaagat gatcgtcaag ccaaatggaa tgatgacagc
    17281 aatgatcatt gcgatgatga aaggtaccca tgtttctgct tggatagcta gtattcctgg
    17341 caaaccgcct actccgatcg cgttagctcg aacacccatc aagttagcaa acatgccagc
    17401 taatccagag ccgaccattg cagcgacgaa aggatagacg tatttcaaat tgattccgaa
    17461 catagcaggt tcagttacgc ctaagtaaca agaaatcatt gctggaatcg agatttgttc
    17521 ttctttttta ttcccacgat gtaagaagat gatggctaag actgcagagc cttgggcgat
    17581 atttgataaa gcaatcatcg gccataaatt cgttgatccg aaatctgcaa tcagctgcat
    17641 atcgatggca ttggtcatat ggtggagacc agtaatcact aaaggagcat acaggaatcc
    17701 gaatacggca ctaaacaacc agctgataga agacgtcaat ccagtattta cgatatttga
    17761 gatccagctt ccgactgtcc agccgatagg acctaaaata acgtgtgcag ctaaaacagt
    17821 tggtaacaat gaaaacaatg gaacaaaaat catcgagatc gactgaggga tatatttgcg
    17881 gaagaagatt tctagatacg ctaacataaa ccctgccagc atggctggaa taacttgcgc
    17941 ttgataacca atcatctgga cttgagcaaa accaaaatcc caaaatggaa tatctgctgc
    18001 ggctgtggaa gctacactat aagcatttaa taattgcgga gaaactaacg taattcctaa
    18061 aacgattcct aatatttgtg tagtacccat cttttttgca atactccaag tgatacctac
    18121 tggaagaaaa tggaaaattg cttcaccggg taaccacaaa aaggcattga caccattcca
    18181 aaacttcgag tgttcaacga ttgttccacc aagactttca aactggatac cttcaagtac
    18241 atttctgaat ccaaggatca atccaccgac aatgattgca ggaatcagtg gtgtaaagat
    18301 ttctgctaaa acggcaatag cacgttgaac gggatgaagg ttttgttttg cagctgcttt
    18361 tccttgttct ttggaaaccc cttcaactcc agatactgca acgaagtcgt tataaaaagt
    18421 agaaacatcg tttcctatga tgacttggaa ctgtcctgca ttcgtgaaca tcccttttac
    18481 gctaggtata tcttcgatcg ctttttcgtc cgcttttcct ggatcattca ggacaaaacg
    18541 catacgagtc gcacaatgac taactgcagc aatattttct tttccgccga tatcatgtaa
    18601 cagcttctcg gcatctgctt gatattttgc catatcaata aacccctttc tcttaacttg
    18661 tctatgcaag ttgtttcttc atttactata ctttttttcg gagagaattg caagcgtttt
    18721 attaaaaagt acgagagaaa atgatatcgt tttaaaaagc ttaaaataag cttttcttaa
    18781 aaataggaac attgaaatac aaaaagagct gtagtatagt gaagaaatga tggaagaacg
    18841 agtgagggaa aaaacatgaa taagttcaat gaaatttttt tagatttgga acagaaaatt
    18901 ttagcgaaag aatatcctcc gcattcgctt ttacccagtg agaaccaatt gatcaaaatt
    18961 tatggtgttt cacgagaaac aattagaaaa gcgctgaatc ttttgactac ggaaggttat
    19021 attcaaaaaa aacaaggaaa aggttcgatc gtactggatc ggaatcgctt cgactttcct
    19081 atttctggat tgactagcta taaagagcta caggagaccc aacgtattcc aagtgaaacg
    19141 atcatccata cgttagaaga aacagaagtg acaaaagcat tgaacgagat cactggctgg
    19201 gagatcggtg cgcctgtttg gcatttgata cgcgaaagaa aaatcaatgg cgaagtagtt
    19261 atattagaca ccgattatct attaaaggaa atcgttccta ttttaactcc agcacaagca
    19321 caaggatcga tctatgaata ttttgaaaat gagctttctt tgacgattgc ttacgcgcaa
    19381 aaggagatca cagtagaaga agtaacggaa atcatgaaaa cagcgatgga tcttcacgat
    19441 gacacttatg cagtagtagt cagaagcctc gttcatctgg aagatacccg ctgtttcgag
    19501 tattctgagt cggttcaccg attagataaa ttccgtttcg ttgagtttgc ccgacgccga
    19561 aaagtgtaaa tagttcaaaa gaaagcaaat tgttggcatc tgtccacttt ggcgctatga
    19621 taggatcaca aagggggcat ttttaatgga taaaccaata agaccagaaa aagaagaact
    19681 gaaagaaaag ttatcaccca tggcttatgc agtcacacaa gaaaatgcaa cagaacgacc
    19741 atttagcggg aaatatgatg atttttacga aaaggggatc tatgtagata tcgtcagcgg
    19801 tgaaccgtta ttcagctctg cagaaaaata tgatgcaggt tgtggctggc catcattcag
    19861 caaaccaata acgaaaagac aagtgcgcga aaaagccgat ttttctcatg gcatgcatcg
    19921 aatagaagtt cgaagcaaag aagcagattc tcatctcgga catgtgttta ccgatggacc
    19981 agtagatcaa ggtggtctac gttactgcat caattctgcc tcactgaaat tcattccata
    20041 tgaaaagatg gatgaattag gttatgggga attcaaatca cttgtagaat aatggaaata
    20101 cacaaagagc ggtacaatac ggggatttac tcgatcgtcc gctctttttt tattcaagcg
    20161 attgctattt gaaagaaacg ctccctagac tccttttttc acaaggtgaa atgtgctaca
    20221 ataaagggaa cgtatgtgtg caaaagaaag aggactagaa tatgtatgaa tatctgacag
    20281 gtgtggttac ctttatcaac ccctattaca tagtagtaga aaccaatggt atcggctacc
    20341 agatcgcact aggaaatcct taccgctaca gtagcaaact aaatcaaaaa ataaaaattt
    20401 atgtccatca ggtaatacgt gaagatgcgc atcttctgta tggatttgat tcgctagaag
    20461 aaaagcaact gtttttgcga ttagtaagtg tttcaggaat cggtccgaaa agtgcccttg
    20521 caatcatggc aagcgaagac cactccggtt tgattcaagc agtagaatcc agtgatgtca
    20581 cttatttgac gaaatttcca ggagtaggga aaaagacagc acaacaaatg atcttggatc
    20641 taaaaggaaa attcggtgag ctgagtatcg atacaccttt tagtctattt gatgaagcaa
    20701 acacaaaaga cgctacagct ctatctgaag caatggaagc tctctcggct cttggttaca
    20761 gtgatcgaga aatcaaacgt gtagaaaaac aattaaaaga agtagataat cagacaacgg
    20821 atgagtatct acgccaagca ctcaagctaa tgatgaaaaa ataaggagga gaccaaatga
    20881 cagatgaata cttgttatca ccagaatctg gcgaaaatga actgagtttg gaaaaatctc
    20941 ttcgaccaca gctgctttct caatatatcg gacagagaaa agtcaaacaa gaacttcaga
    21001 tttacatcga agctgccaga aatcgggaag aacctttaga tcatgttctg ttgtacgggc
    21061 ctcctggatt aggaaaaacg acgatggcca tggtcattgc taatgagatg accgtaaata
    21121 ttcgtacgac gagtggccct gctatcgaac gtccgggtga cttagtagca atcttgaatg
    21181 aactggaagc aggggatgtc ctgtttatcg atgagatcca tcgattacct agagtggtag
    21241 aagagatgct ttattcagct atggaagatt tctatgtaga tatcatggta ggacaagggc
    21301 caaccgcaca tccggttcat ttccctcttc ctccctttac tttgattggc gcgacgacac
    21361 gggcaggtat gctttctgca cctttacgag atcgatttgg catcatttct catatggaat
    21421 attatgacga acaggatctg caggagatcg ttttacgttc ttcggatatt tttcaaacag
    21481 agatcattga agaaggggca ttggaaattg ctcgccgatc acgaggaacg cctagaatcg
    21541 ctaatcgctt gctcaaacgg gttcgtgatt ttgcgcaagt ccaaggagac gggaaaatcg
    21601 atcgtcctat agcggatcag gcacttactt tgctacaggt cgatcaggct ggattggatt
    21661 atgttgacca gaaattgttg cgaacaatga tcgagttata tggcggcgga ccagtagggt
    21721 taagtacgct ttcagtaaac ataggagaag agcgtgagac ggtagaagat atgtatgaac
    21781 cgtatctgat ccaaaaagga tttttaaagc gtacacctag agggcgaatt gctactgctt
    21841 atgcctatga acattttggt tacgactatc atatatgatt tttgctttta gattggagga
    21901 aaatgaatga gtgatacaac acgtacgaaa caattgatca aaaacgtatt gattgatttg
    21961 tgccaaacgc aatcttttcg aaaaatcagc gtccaaaaaa tcgcaaacga agcaaaaatc
    22021 aatcgacaaa cattttatta tcattttaca gataaatacg atttgcttcg ttgggtctat
    22081 tgtgaggatg cattgcatta tttagatcca caatgtcttt cacttgataa ttgggaagag
    22141 caagcattga aaatgctgaa agcaattgct gagaagaaag aattttatgc aaatactgtg
    22201 ctttctgacc cagaaatttt acaaaaagag ttttctcaac tgatccaaaa atcatttatc
    22261 aagatttttg aacaaatgga tgaagaaaga caactttctg caagagacaa actattttat
    22321 gctcgttttt tttcttacgg ttgcagtggt gtattagtca attggatcac gaatgaatat
    22381 gaagaaacac cgatggaaat cgctatgcag cttttccgtt tagccaagga tacggaatta
    22441 tattcttatc gtctttatgc aaaagaagag ttggaagaac agtaatagaa aaattttttg
    22501 ttggaaaagc aataatcgct aaaaggagat ggggaaatga caaaaatttt atttgtttgt
    22561 ttgggaaata tttgccgttc accgatggca gaaggcttgc tgagaaaacg aatagcatta
    22621 gaaggaaggg aagcagaatt ttttgtggat tctgctgcta caagcacgta tgaagttgga
    22681 aagacaccgc accctggaac gaaaaaaata ttaaaccaag aaaaagtaga tatgacgaat
    22741 atggttgctc ggcaaatcac accccacgat tttgaaactt ttgattggat cattggcatg
    22801 gatcaagaaa atgtagaaga actgaaacga agagcaccac gctcagcgca ggggaaaatc
    22861 catttgtttt taagtagcat tcctggaaaa gaaaaagaaa atgttcccga cccatactat
    22921 accaataact ttgatgagac atatcacttg atcacagaag gcctgaatca ttggtggaat
    22981 atttggattg atgaaaataa aataacaaac aatttgtaaa gttaacgctt tctttttaag
    23041 gcgatgttag agcatttcct tgtttttttg taaaatgtta ggtaaaataa aattaattaa
    23101 gtaacacttt cttagctaaa ggaggagtgc attcgatgaa cgaagagaca gtatcgccaa
    23161 tgaagaagct tacgaagtta gttactcata cttcgtatca actttttgat tcttttgtaa
    23221 atgacactga agaacatgct aagaatgtac gattgcaagg aaagtttatt cttgagctgc
    23281 aaaaagctgc tactgaacat agtctagtta tcttacaagt aagagcaaat cgtttgagta
    23341 gcaagtatga aacgatctca ggctgggtgg cgacaaaaac ggtcgaaaaa gaccgagtga
    23401 tgatccgcct acaaaacgaa gagcagcaga tccggatggt tcctgtagaa caaattgaaa
    23461 aaataacaat cctttcacca gcaggggaac aggaacggtt atcaaaataa tttataccag
    23521 atagaaaagc acgtatgagc ttgtaccatc aatcattact aatcaaaaat aaccgaatgc
    23581 tttaagctga tatcagtaaa acggaacgtt ttaggatgag tatcacagca tgacagcatt
    23641 gggttgatta gttgaatcga ttggatggta caagtttttt tgataaaaaa aggtcctgct
    23701 agccggggag ctagcaggat aaggagttaa aaatgaaaaa gtgttgttag ggttgtttgt
    23761 tggtatgctt atataatagt cactagttgt gaatattttg tgacgaaagt tttcgaaagt
    23821 tgttaagtt
//
LOCUS       DADLIO010000041        23642 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.041, whole genome shotgun sequence.
ACCESSION   DADLIO010000041 DADLIO010000000
VERSION     DADLIO010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23642
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.041"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(458..1087)
                     /gene="udk"
                     /locus_tag="JOX41_001751"
     CDS             complement(458..1087)
                     /gene="udk"
                     /locus_tag="JOX41_001751"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HAY6449495.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1171..1866)
                     /locus_tag="JOX41_001752"
     CDS             complement(1171..1866)
                     /locus_tag="JOX41_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="noncanonical pyrimidine nucleotidase, YjjG
                     family"
                     /protein_id="HAY6449496.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1879..2595)
                     /locus_tag="JOX41_001753"
     CDS             complement(1879..2595)
                     /locus_tag="JOX41_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HAY6449497.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2925..3533
                     /locus_tag="JOX41_001754"
     CDS             2925..3533
                     /locus_tag="JOX41_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HAY6449498.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEEESTGEGGEPEVIGSTEE"
     gene            3858..4181
                     /locus_tag="JOX41_001755"
     CDS             3858..4181
                     /locus_tag="JOX41_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HAY6449499.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4363..5733
                     /locus_tag="JOX41_001756"
     CDS             4363..5733
                     /locus_tag="JOX41_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HAY6449500.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5863..7164)
                     /locus_tag="JOX41_001757"
     CDS             complement(5863..7164)
                     /locus_tag="JOX41_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAY6449501.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYYYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKTE"
     gene            complement(7518..9509)
                     /locus_tag="JOX41_001758"
     CDS             complement(7518..9509)
                     /locus_tag="JOX41_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /protein_id="HAY6449502.1"
                     /translation="MATTHNTKKISMTGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9653..9919)
                     /locus_tag="JOX41_001759"
     CDS             complement(9653..9919)
                     /locus_tag="JOX41_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAY6449503.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10429..12555)
                     /gene="pnp"
                     /locus_tag="JOX41_001760"
     CDS             complement(10429..12555)
                     /gene="pnp"
                     /locus_tag="JOX41_001760"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HAY6449504.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12743..13012)
                     /gene="rpsO"
                     /locus_tag="JOX41_001761"
     CDS             complement(12743..13012)
                     /gene="rpsO"
                     /locus_tag="JOX41_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HAY6449505.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13263..13826
                     /locus_tag="JOX41_001762"
     CDS             13263..13826
                     /locus_tag="JOX41_001762"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAY6449506.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(14079..14600)
                     /locus_tag="JOX41_001763"
     CDS             complement(14079..14600)
                     /locus_tag="JOX41_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HAY6449507.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14603..15445)
                     /locus_tag="JOX41_001764"
     CDS             complement(14603..15445)
                     /locus_tag="JOX41_001764"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HAY6449508.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELIALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15438..16163)
                     /locus_tag="JOX41_001765"
     CDS             complement(15438..16163)
                     /locus_tag="JOX41_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HAY6449509.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEMAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16339..16635
                     /locus_tag="JOX41_001766"
     CDS             16339..16635
                     /locus_tag="JOX41_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449510.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17203..18795
                     /locus_tag="JOX41_001767"
     CDS             17203..18795
                     /locus_tag="JOX41_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750719.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAY6449511.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18808..19548
                     /locus_tag="JOX41_001768"
     CDS             18808..19548
                     /locus_tag="JOX41_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAY6449512.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            19716..21065
                     /locus_tag="JOX41_001769"
     CDS             19716..21065
                     /locus_tag="JOX41_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAY6449513.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(21193..21783)
                     /locus_tag="JOX41_001770"
     CDS             complement(21193..21783)
                     /locus_tag="JOX41_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HAY6449514.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            21930..23282
                     /gene="brnQ"
                     /locus_tag="JOX41_001771"
     CDS             21930..23282
                     /gene="brnQ"
                     /locus_tag="JOX41_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAY6449515.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         6770 a         4761 c         4502 g         7609 t
ORIGIN      
        1 ggggtgcgac aaaagagctt cttcaaaaaa ataagtcgaa atctcacaca aattcgagaa
       61 ataattttcg taagtttctt cttatttatt gcatctgacc acttctgtta caacctctcg
      121 ttaaacggtg ttcaaaagct tgcatctacg ataataagcc caacccaacg aaaaacgtga
      181 ggagctgttt tatttggatg ctcttatcgc ttgatgcaaa gacagctttt ttacaacctc
      241 tacttcacgg tgctcaatca gctgaccttc ggtattagct caaaaaacgg taaaatataa
      301 acagctattt tccgtttctt ctttttaata cttaggtcaa gatgctgttt tcacaacctc
      361 ttgttataaa taaaaaaaca gttggctggt gactgttcaa aaagcagaat ccttgctttt
      421 caaacggtcg cagtccgttc aactgtttcg ctgcgcacta tttatggttt aagaaactag
      481 ctacttttgt tgtaatcaaa tcaatagcaa cgtggttttc tccgccttct ggaacaatga
      541 tatccgcata gcgcttcgtt ggttcgataa attgatgata catcggttta acaactgtca
      601 aatattgttc gatcacggag tccaatgtgc gtccccgttc ttccatatcc cgtttgatac
      661 gacgaatgat acgaatgtca tcatctgtat ctacgtatac tttgatatcc atcaagtcac
      721 gcagacgttc gtcttctaaa atcaggattc cttctagaat gatcacttct tttggttcct
      781 gaatgatcgt tgcctgactt cttgtatgcg ctacatagtc atacacgggt ttttcaatgg
      841 ctttatagtt cagtaagtcg cctacatgct gaatcagcag atcattatca aaggcaaatg
      901 ggtgatcgta atttgtgttc aatcgttctt caaaactcaa atggctctga tccttgtaat
      961 aagaatcttg ttcaagcatc atgatggaat ggtccgggaa gttgttgaaa atcgcacggc
     1021 tgacacttgt ctttccgctt ccggatccac ccgtcacacc aatgataatt ggcttgcttt
     1081 ttgtcattga ctaaaacctc tttcgtatcc gttttttcat tctaatctat tatagcgaaa
     1141 aaacacgaaa atgctatatt tttctgaaaa ttaatccttt tcaatttcca ataatgaata
     1201 aagttcctct aatgaatcga ttcgataagt aggctggatt tcttcgattt ctggtaattt
     1261 atttctattg aaccaaatcg tatcgatccc tgccatattt cctcctttga tatcagaagt
     1321 caaagaatca ccaatgatca cagtttgctt tttatcaaaa ttaggaatgt gggaaaagac
     1381 atgatcaaaa aattctttca tcggcttttg cgctccgaca gcttctgaga caaagatatc
     1441 cttgaagtaa tcaagcattc ctgcatctgt taatcgccga tgttgcgtgt gcgacacacc
     1501 gttcgtcaca atataaagat cagcatgcgg atggaccttt ttcaggattt ctagacttcc
     1561 tggaacaaga tcatgacctt ggttcaagta gtggcggtag cgtttttcca tttgatcact
     1621 atctactgtt ttcccaaatt gctggaaaag taacccaaaa cgactgccta ttatttcttc
     1681 tcgtgatagt ctgccttttt caaactcctg ccataaatga tgattcaaag ccttatagct
     1741 ggtttcgatt tctggtgtca atgtgattcc ttgttctgca aacaaagcac ttaaagcatt
     1801 ggcttcagtt aattgaaaat ctaacaatgt atcatctaca tcaaacaata aagttttata
     1861 tttcatcttt ttgacctcct atttaaaata aatacttaac tttttcatct ctgctaatgt
     1921 caacgatcga tactcgccta ctcctagctg ttcatctaat tccaatggtc ccatgcttag
     1981 ccgtttcaat gcggtcactt tctttccttg ggctaagaac atctttttga cttgatggaa
     2041 ttttccttct tggatcgtca ataaaaccgt actttggtgc ttgtctgctt tgagtatttt
     2101 taaatcagcc ggcttacatt gatacccatc agcgaatacg attccatttt caaatgctgt
     2161 tacgtctgcc ggtgtcaccc tttcgttcac aactacttga taagtctttg aaaccttttt
     2221 ttctggaagt agcatttcat atcccaattg tccattcgaa gtgatcagca atagtcctgt
     2281 tgtatctcta tctagtcttc ccactggata taatggttgg aaacgatcgg cacttgcaat
     2341 cagatcgatt actgtcgtct tttctggatc tgatacagct gtaacagctt tttcaggttt
     2401 attgagaaga taataggact catttgtttc taagtgttca cctgctactt cgatttgatg
     2461 cagtaaacta tctacatttc gattttgtcg aaattcgact gtgccatcta tcatcacttg
     2521 cttcaaagca aacagccgct tcatttcctt gcgtgtcgtt tctaattttt cttctattaa
     2581 tttatctaaa cgcatgctgt ttcctttctt attactacta attaattata ccttgaatat
     2641 tcttgcttgc aaatacatca tcatagttat tccttgactt aattaacagt tcacgttacg
     2701 gttaaatagt aaagtgaatt ggatttctca tacacagcgt aatgacctgg tggagaaaag
     2761 ttgaatcctg actttctaag gggagatgcg cgcatctctc cttttgcgct tttttaagcg
     2821 ccctgccttc gatgatgtgc acgagattag cctttagaat tcacttaaat aaaatctgtc
     2881 cgttaccaaa gcagacagtc acattttaag gaggaatttt ggttatgtca gtatcattag
     2941 aagtaagtaa aagagaagta cgtccccgtt cattaagaaa caaacttcgt cacgaaggga
     3001 aagttccagc tgttgtttat gggtataaag tagaaagtac ccctatctca ttcgatggtt
     3061 tgacactaag caaattgttg cgtgaacatg gagcgaacac agtcatcacg atggacatcg
     3121 atggacaaaa agtcaataca ttggttcaca agatccaaac gaacactttt accaatcatt
     3181 tcgaacatgc agaatttcta tctgtaaaca tgtcggaaga aacagaagtc gaaacagaag
     3241 tcgttcttgt tggcgaatca gtgggtgcta aatctggtgg agtgttagct caaaacttgt
     3301 atacagtagt cgtatctgct acaccagaca aattgcctga acgaattgaa gttgacgtga
     3361 caaacttgga attaggtgat tctattacag tagccgatct tccaaaaaac gacgattaca
     3421 aattcgtgac cgacagtgaa gagcaaatcg ctgctgtagt cgctcaaagt gaagaagaag
     3481 aaagcacagg tgaaggtggc gaaccagaag tgatcggttc aacagaagaa taatactgaa
     3541 acaatcaggt ggtgttagaa gcggcgggtc agcagctttt aacacgcctt ttttatttct
     3601 aatcgtttat tttcatatgg ggcttccact tttgtaaatg gctttacaaa cgaaaaatcc
     3661 taatttacca agcttttcct cgcatacttt tatcgtacct ttataaaaat ttatactttg
     3721 aaaaaaagta ttcaattatt gttgcatttt tcctgattct ttattagaat gaaccctcgt
     3781 tgaagtaagt atttctagtt tatcctagga ttaattataa aaataaaaca ttcgttgatt
     3841 cgaaggaggt taaacagatg tttgaaagtt ttgatagcag ccgcaaccgt tacgcttcag
     3901 ttggtgtcgt atcaagtttg ccagatgaat tgattgacag tatatggttt attattgacc
     3961 tagatcttaa gggagtcatt ccattagaaa atatattaac ctttgatttg atcgaaaatc
     4021 gtggaaaagt gacgatgcat ttttctcaag caggaagcaa tgtggaaatg gatattgatt
     4081 tgccgtttgc ctattcgaac caatttcctg ctcaagtata cgcctatgat gacggtacga
     4141 gagaaacgat ccttttacca agtgagatta gacaatatta aggtgataga taaacgtgga
     4201 tgtcccttat tttacagacc aggccaagtt gttgattctt tgactcaatt cttggcttct
     4261 ttttatggag tttcataaat tatcattgat ttctaattgg tattctcagg ataaacgcta
     4321 tatactacta actaaatttt aaagatataa ggagtttaaa agatgcgcga tttaacaaaa
     4381 ggaagccccg ctaaactgat tttgatgttc actgttcctt tactgatcgg aaatgttttt
     4441 cagcagttct acaatatgat cgatatgatc atcgtgggtc agacgctagg taaaaatgcg
     4501 ctggcagcgg ttggtgcaac tggaagcctg acatttttga tcattggctt tgcccaaggt
     4561 ttaacagctg gtttagccat tattaccgca caacgttacg gtgcaaaaga ttatcggggt
     4621 ctgaagaaaa gttttgctgc tagtgttgtc attagtcttg tcgtcactgt gattttaact
     4681 gtcctaagtc tcctgtttat tcgtccgatg cttcaattga tgcaaactcc tcctgaaata
     4741 cttgatcaag cacaaacatt tatttcaatt attttattag ggatctttgc atcagtcagt
     4801 ttcaatttgc tttctaatgt cattcgcgca cttggtgaca gccgcacacc actattcttt
     4861 ctgatcattg cggtcatcat caacgtcgta cttgatttga tctttattat ctattttggc
     4921 atgggtgtgg aaggtgcagc tattgctaca gtaatcgcac aagtttcttc cagcgtactg
     4981 tgtctagtgt atatcaagaa aaaaatgcct ttgttacagt tacgcaaaaa agatttcaaa
     5041 tttgaaaaag aagagtttgc tgtacaccta aatgctgctt tgccaatggc gtttcaatct
     5101 tcgatcatcg ctgttggtgc tatcgtgtta caagcagcac taaatagtct agggacagat
     5161 gtcgtagctg ctcaagccgc tgctggtcgt atcgaccaat ttgcaaatca gccgatgatg
     5221 tcatttggta ttgcaatggc aactttcact gcacaaaact atggtgcgaa agaatatggc
     5281 cgaatcttgc aaggggtacg tcaaacttta ctgatgagtg tcggatttag tctcttagca
     5341 ggtgctatcg tcattttctt cggtcatttc tttgttcaat tgtttgttag cccatcagaa
     5401 acacgtgtat ttgaattagc acaaacctac ttcaatatca atgggtctct ttactggatc
     5461 ttagcagtcc tgttcatttt acgctacaca cttcaagggc ttggacaaag caagatccct
     5521 acgatcgccg gtatgatgga attgcttatg cgttcttttg cagctatcgt tcttacagga
     5581 atgtggggat acccaggagc agcagcagct tctcctttag cttggatcgg ttctgttgcc
     5641 gtgttgcttt actcttatat gcgttcgatg aaacaattga aacacatggg tgaagaggaa
     5701 catttcacat tagaacatgc agaagcaaga tagccttgat taaaagaaat cgttgcggct
     5761 aaaaatgaaa acttttattg aaaatatctt cttcgtttac cgaaaacagg ttttttagat
     5821 aacaaaaagg ctgtgacaaa aaatgtcaca gccttttttc ttttattctg tttttctttc
     5881 cgtggactct actttgaaat aatcgatatg tgcatgctgg tattctaata ccgtgaaacg
     5941 gaatgatgca atctcaatga ttgttcctgc ttttatttct ttatatcggc tagaagcaaa
     6001 gcccgcaagt gtagtaaaat tcgtttcttc aaactctgga atctctacat gaaaataacg
     6061 ctggaaatca tctaatgtta gtttgccgga gatgatataa gagccatctg actgttccgc
     6121 tatcaatgct tcgtccaaat ctgtctcatc tcggatttcc ccgacgattt cttctaaaat
     6181 atcttcaatc gtcactaagc cgcttgtccc tccgtattca tcttttaaga tagcaatatg
     6241 cttacccttt tttcgcatga tcgtcaataa tttttttata gggatcgttt cagttgttac
     6301 gatcggctct tcaatcaact gttctactgt cagctggtca tctttataag attgcttgat
     6361 caaatctggc aaggtgacat aacctaaaac attgtctttt gattctaaga taaccggata
     6421 gcgagtatgt ccttgttcaa tcgaagcttt tatcgcttct ttgacggttt ctgaagcttc
     6481 gaatacttgc atggacgtac ggtctacttg tatatctttt gccaaggtat catcaaattc
     6541 aaacacgttt tccaaataat aatattcttc tttggtcaac tctccttttt cataagaatt
     6601 caatgcgact aatgtcagct cttcttgaga caatgtctct tctccttcag atacgagacg
     6661 cacacctaat agcttcccta gccctgcagc tgaatgattc aatacccaaa taaaaggaaa
     6721 cattacttta taaaaataat gaagtggttt aactacgaac aagacgacct tctccgtatt
     6781 gacgatacta tagctcttag gaagcagttc gccaataacc acatcgatat acgtaactaa
     6841 aataaatccc agcgccacag agattgtact gctaatagcc gaactaaaag gtagtttacc
     6901 gatcactggt tctagtaaag ccgcgacaga tccttcaccg acccacccga tgatcaaacc
     6961 ggttagcgta attcctaatt gactagctga taaatagtta tctaaatggt gtgtaacatg
     7021 aagagctagc ttggcgttct ttacattttc cttttctagt tgttccaatc ttgatcgtct
     7081 gattttcact aaagcaaatt cacttgctac aaaaaatgaa gtaattgcaa tcatcaaaaa
     7141 taaaataatg aaattgataa ccatattctc ccgcctttct ctttttctat tgtacccttt
     7201 ttctacaaaa agattgaaaa taatgcgtat tcatatttag gaataaaaaa ggagatgcgg
     7261 catttttcag ccacatctcc ttatcacttc aaaatcattg cgttacttgt tgctaaacag
     7321 ctttttcatg acctctgata aaaacggtat tcaaaagctt gcatctacgg cattaagccc
     7381 aaacagatga aaaacatgag aagctgtttt tatctgctcg ttcttactgc ttgttgcagt
     7441 acagcttttt catgacctct gataaacggt gttcaagtag ctgacattcg acattagttc
     7501 aggtcaaagc gctactttca caaccgctct ttcaaccatg ttttccgagt atttccaatg
     7561 ataagcggaa cagtttcatg ttttacttcg ctgtactcta gcccaaacca tgtttctggc
     7621 gaggtagcga tttttttgat tgccagtttt gcctgcatga tttgacgttg ccattttcct
     7681 agagttgtca cattggaaac tacttcatca atcaggacaa attggaaatc gccaacttct
     7741 cgccctggtg tcagagagta tctttgtggc tgttttggca aacggccttg tttcatcaaa
     7801 tcatggatga cttggcgaac atatacgttg atttcctgtt ggaccctgaa acctaagaac
     7861 agattcactt ggacaataaa atcagtgtcc atcatatcta cttgatattc tttcgtatat
     7921 ggctcatccg tcacttccac atgaacaaac caatagactc gtgctctttt aggccgttta
     7981 tctaaaatcg aatagatgaa ctgtcggcca actttatctt cagccatatc aggaaccaag
     8041 aagaccacat ttgtctgata gattggtaaa gaagtatcat cacgtaattc tctaagctgc
     8101 gggatataat ctctcaaaga cacatcctcg gttgacgatt cgcgaataat gttcccttgt
     8161 tcccaaataa acatcacgac taagatgatc aaaccaatca gaacggctac aaaaccgcct
     8221 cggaagaatt tgacaacact tgagataaag aaaacgactt ctatcgcacc gaagaaaaag
     8281 gtaactaaat atgcaagcca acgagaatgc ccattttgga taagataaaa gtaaagcagt
     8341 gctgttgtca tcaacatcgt cacagtgatc gatagaccgt aagcagcttc catatgatga
     8401 gacgttcgga atgtgacaac cactagagaa caggcgatcc ataaaatcag attgactgct
     8461 gggatataca tttgcccgat actgttccca ggatacatga tctttaaccg aggcagcagt
     8521 ttcaacttga ttgcttctga aactagcgta aacgaacctg taatcaatgc ttgcgaagca
     8581 atgactgcag cgactgttgc aaaagcaacg ccgatcacga tccaactttg aggcatcatt
     8641 tggaagaatg gattcaggtt cttgatttgc tgtgcttcag ggttttgata aacattcaac
     8701 aaccacgcag cctgcccaaa ataattgata accaaacaaa ttttgacgta aggccagctc
     8761 agacgaatat ttcgtttgcc gacatgtcca agatcggaat aaagcgcctc tgcacctgtc
     8821 gtagccagga aaatatttcc aagaatgaac aagcctaatt tgttatctgc actaaaaagc
     8881 agctggatag cataataagg attcagtgca cggataactg tccagtcttg actgaagttc
     8941 attaatccca ttacgcctaa aaaagtaaac caagcgaaca tgattggtcc gaatgctttt
     9001 ccgacaatat ctgtaccaaa gcgttggacc atgaataaaa caaaaataat aactaaagtg
     9061 ataatgacga tcacgttctg gttattaccg aaccggtcaa aaaactgcgg aattcctcgc
     9121 aagccttcaa tcgcagtcgt taccgtcaca gcaggggtca ataccccatc tgctagtaag
     9181 gcagctcctc cgatcattgc aggaatgatc aaatatttcc caccttttcg gacaagtgtg
     9241 tagagtgaga aaattccacc ttcaccatgg ttatctgcat tcaatgcaat cacgacatat
     9301 ttgattgttg tcagtagagt caatgtccaa aaaatcaatg agactgatcc gataacaaaa
     9361 tcaggattga ttcctgacaa tccgccatta tcttcaacaa tcgatttcat aacgtaaagc
     9421 ggacttgtcc cgatgtctcc gtagacgact cccatcgcta caagcaggcc agtcattgat
     9481 atctttttgg tattgtgcgt tgttgccacg tttttccctc atttcttgtt atatggatat
     9541 cctttaggta agcttgaatg atagatgata ttcttatcca tgacacccgc tttcctaaat
     9601 tgcttctaat tatccaagta acacactgaa gtgtcaactt atttgaataa aattattctt
     9661 tctttggacg ttctctgata cgtcttgcca caaatgaata aagagcaagg caaaaaattg
     9721 cacccaataa tgctggtatc aaataaaaac cgccgagttc cggtcccagt ggtcctagta
     9781 aaaattcgcc gagccaacta cctaaaaaac cgataatgat atttccagat acgcctcccg
     9841 ggacttcctt tcctaaaatt gcgccagcta tcaaacctaa tataccgccg ataaataacg
     9901 accataaaaa attcagcatc tcctttccct cctttatcca tatttctcac ttttatttta
     9961 cgctttattc agaaggactc caaaaatatg cgccaagaaa ctccagaaaa aaagaagttg
    10021 taacaaaagt gttcagctta tttccgtaga agctgcttct ggaacaccgt gaatcagagg
    10081 ttgtgaaatc agcggtttga cctgagtatt agagaaacaa acggaaaaat agttcctcat
    10141 attttgccgt tttttgagct aatatcgagg gacagctgat tgaacatcgt ttattggaga
    10201 ggttgtaaaa aagctgttct gcatcaagta ataagaacag ccaaataaaa acagctccta
    10261 atgtttttaa cttggctgga cttattaccg cagatgcaag cttttgaaca ccgtttattc
    10321 gaaaaaaaag gactgtgaca cggcttttgt cacagtcccc ttttttcgaa taattattgt
    10381 ccccctgtca ccttcacgat cacaagtaca ttattcctat gaattaaatt atttttcttc
    10441 atttttcgtt gaaccatctt cgttcaacat tgcttttctt gacagattta cgcgtccttg
    10501 tttatcgatt tcagttactt tcacaaggat ctcatcacct agtttaacaa catcttcgac
    10561 tttattgaca cgatcgtttg ctaattggga aatatggaca agtccatctt ttcctttgat
    10621 caagttgacg aatgcaccga atttttcgat acggacaact ttccctagat aaacttcacc
    10681 aactttgact tctttggtca aatcttcgat gatcttgata gcttttttga tcatttctgc
    10741 atcagctgaa gcaatactta cttttccatc ttgatcgata tcgattttca caccagtttc
    10801 atcgatgatt ccgttgatcg tatcgccgcc tttaccgata acatctttga ttttagcagg
    10861 ttcgatctgg atcatttcga tttttggtgc atattggctt aattcttcac gtggagcagc
    10921 aatcgttgaa gtcaattctt ctaagatttc catacgtgct tgttttgctt gagttaatgc
    10981 ttcagttagg atttgttctg tgattccttg aatcttgata tccatctgta aagcagtgat
    11041 accatctttt gtaccggcaa ctttaaagtc catatcgcca agatgatctt ccagcccttg
    11101 gatatcagtt aggatcgtat agttttcacc atcagaaaca agtcccatcg caataccggc
    11161 gactggcgct ttgattggta cacctgcatc catcaatgct aatgtgccag cacagatact
    11221 tgcttgggaa gaagaaccat ttgattccaa tacttctgct actaaacgga tcgtataagg
    11281 aaattcttct tctgaaggga ttacttgtgc taacgcacgt tcacctaatg cgccatgtcc
    11341 gatttcccga cgccctggag agcctgcacg tcctgtagaa ccaacagaaa attgagggaa
    11401 attgtagtgg tggatgaatc gtttgctgac ttccacccct aaaccatcaa tgatttggtg
    11461 ctctcctaga ggtgcgagtg tacaagctga taaagcttgt gtttgtcctc gtgtgaacaa
    11521 acctgatcca tgtacacgtg gcaataagct gacctctgat gacaatggac ggatttcatc
    11581 caatttacgc ccgtcaggac ggatcttatc gatggtgatc aattcacgta cgacatcttt
    11641 ttcaagatct tctgtgattt gtttaacttc tttcaacaag tgatcttcat cttcatgacc
    11701 tgcaaatttc tcagcataag cttcgcggat atcgatcttc acctgctcga tattatcttc
    11761 gcgagcaagt ttttcttcag tcattactgc tgctttcatt gtagcgtaag aagcatcaaa
    11821 gatttctttt ttcaatactt catcaacttg cagtaaagtc acttccattt tttctttccc
    11881 tactgcttga acgatttctt cttggaaagc aactaactct ttgatagcgt caaaaccaaa
    11941 cagcaatgca ccaagcatgt cttcttctga aacttctttc gcgccgcttt caaccatatt
    12001 gatggcttgt ttcgttccgg caacagtcaa ttcgatatct gtttgttctg cttgttctac
    12061 tgttggattc aagacgtact cgccatttac acgaccaact tctacgcctg cgattgggcc
    12121 gtcaaatggg atatctgaga ttgatagtgc taaagaagaa cctagcattg ctgccatagc
    12181 tggcgagcag tctgtttcta cactcatcac gatgttcgtt acttggactt cattacggaa
    12241 gccttctgca aacatcgggc gaattggacg gtcgatcaaa cgggcagtca atgttgcttc
    12301 cgtacttgga cggccttctc gtttgatgaa acctccaggg attttccctg ctgcatacat
    12361 tttttcttca taattgatcg ttaatgggaa aaagtctgta tcttttgctt ctttagaggc
    12421 cacagctgca cttaagacta ctgtatctcc ataacggact aaaacggctc cgtttgcttg
    12481 ttttgctagc tgaccgactt cgatttgtaa gggacggccg ccccatgtcg ttttgaatac
    12541 ttgtttttct gacataactt ctccttttcc ttctcgtgaa agcaagacgc tactaaacaa
    12601 atgaaaactg ccgaaagccg tcttttgagc agctttcatt tggttagtag gagtccatct
    12661 agcttgatca cggaatttta cttaattgat atacgagtaa aaaaagtgag attcatgtga
    12721 atcccactct ttttgactaa aattaacgac gcaagcctaa acgtttgatc aattcgcggt
    12781 aacgttgaac gtcagtttta cgtaagtaag ctaacaagtt acggcggtga ccaacttttt
    12841 tcattaggcc gcggtatgaa tgatggtctt ttttgtgcac gcgtgcatgt tcattcaagt
    12901 ggttgatttc ttcagttaat acagcgattt gtacttctgg agaaccagta tccccttcat
    12961 ggcgagcgta ttcgttgatg atttcattct tgcgttcttt tgaaattgcc atttctttca
    13021 cctctttcga ttattcccct gcgactgagt aaaacgttgg tgattcgctt aaccaagtgg
    13081 caggtcatgt gcctagagca cacagctata ctttacctga aaccgggttg aaaatcaagt
    13141 agttaatcat taagaaaagg tagttttcaa acaatcttac tactactttt ccatttttgt
    13201 ggtaaactat aatgcgaaaa tagacttgaa acacagtctt ttaagaaagg ggtacatatt
    13261 ccatgattac aatggatgat atcattcgtg aaggaaatcc gaccttacgc gaagttgcaa
    13321 aagaagtttc tcttccatta agcgaagaag atatctcttt aggaaaagag atgcttgagt
    13381 tcttaaaaaa cagccaagat ccaatcaaag ctgaagaact acacttacga ggcggtgttg
    13441 gcttagctgc tcctcaatta gatatttcta aaagaatcat tgctgttcac gtaccaagtc
    13501 ctgacccaga ggcagatgga ccttctctaa gtactgttat gtataatcct aaaattttga
    13561 gccattctgt tcaagatgct tgtttagggg aaggtgaagg ctgtttatct gttgatcgag
    13621 aagtaccagg atatgttgtt cgccatgcca aaatcactgt gtcttattat gatatgaatg
    13681 gtgaaaaaca caagattcgt ttgaagaatt atgaatcgat cgtcgttcaa catgaaatcg
    13741 accatatcaa cggtgtgatg ttctatgacc acatcaacga tcaaaatcca tttgcactaa
    13801 aagaaggcgt attggtgatc gagtagagaa ttggcaggtt ccttcgatac tatgctacaa
    13861 gaaagcttta taaaaaaggg gagtgctcaa aagctgcact tccctttttt atgtttctcc
    13921 actaatcgaa atttagatag acatctagaa atcgcaattc caaaaaattc tgtgtattgg
    13981 atacgcatct tttcttattt tttcttattt cttccatatg ggtgtttatc tcagagatga
    14041 tagaatagtt tctaggataa aaagtagcag ctacgatgtt atccttcgta gaggattcct
    14101 gcttcagcta gtttttgttt gatgtttttc agcatatgct tttctgggta gcggatcgta
    14161 tgcagatgga tgccgcctgt taattcggat aacaaagtag cattactttt ttgataacgt
    14221 ctcataaagg aatcgatatc ttgtggcgtt ttgatgtgca aagttcctgc taactcaccg
    14281 taaaggggat gttccacaat tacatcaatg atttcaccac cattttcaac gattagtctc
    14341 agttcttctt ctgtttgatc ttttccatgc tggacagcga ttttactgat gtgcccagta
    14401 ttggtttctt ctgtttcgag gatataacct cttgctgttg ccacgatact tttacctgca
    14461 gctcgtagta aagcaatatc gcctacaatg atctgacggc tgactccaaa agttttcgca
    14521 aacttgctag cactcactgg tttttctgta tttgccaagg tttgcatgat ttgttttcgc
    14581 cgtgtctctc cttcgatcac acttattcct ccttcatttt gttttggtat tcgcgcgagt
    14641 gtttcatcaa atcaacatac gtatctgtta ttgtttcctt atatccctta tttttcagca
    14701 gactaacaac tttatccaat acttgctgct ctctttttgc atcataaact gcttggtttt
    14761 cttctttttt cacttgtcct attttagtta ccgtatccat tcttttttct aataaagcaa
    14821 tcaactctcg atcgatcata tcgatcttat gacgtaatgt ttcaagagac tcttctgtta
    14881 gttcttcctc tactgtcttg atgatacgag caggatttcc tgcaatcact acattgtcgg
    14941 gaaaagattt ggtcacaacc gaacctgcgc cgactactac gttgtcccct agagtgacac
    15001 ccggcgtgac gataactcct ccgcctaacc aaacattatt accgatttta atgggttttg
    15061 cgtactccag accgctgtta cgtttcactg gatgtagtgg atgcgtcgcc gtgtaaagct
    15121 ggacattcgg agcgaacatg cagttatcac cgatttcaat cgtgctgaca tctaaaaatg
    15181 tacaattgaa atttgcataa aaattctccc caacaaatat attatatccg taatcaaaat
    15241 tgataactgg ctccatatag atttttttcc ctgtacggcc aaaagtctct ttcaacaatt
    15301 gggatcgcag ttccgctgat tctgcttggt tgatgatttg gctttgactt cttgcaaaca
    15361 tacggtcggc aaccagctca ggatcattgg caaaataaag ctcgcctgca atcatttttt
    15421 ctttttcggt tttgaattca gtcataatct gctcctaatt cttgtatttt tttgaaaaca
    15481 accgctccgt cttcttgaat aaacgtataa ggctccgcta aataaacagg cgtttgattg
    15541 attactaaga ttttggctga cggctggcga aactgtacca gatcacaaaa cggatgaact
    15601 tgaaaactcg ttccaacaat gacgatcagc tctgcttggc tgacggcata agccgcctgc
    15661 tccatgactc catcttgaaa cccttcacca tataacacga tgtctgggcg tatttgtcct
    15721 ccgcatgctt gatgtttgtc gctgtgaaga tattctttcc agtctaccgt ttgttgacat
    15781 tttcgacaat gacattgata caaacttcca tgaaaattga cgagttgcgg gcttttagcc
    15841 tttgcgtgca aaccgtcgat gttttgggaa acaacccaaa catttttttc tttcgctaga
    15901 tgtgccattt ccaaatgaat gatattgggt tttgcttcag gatgataaat ctttttgaca
    15961 aattgataga atttatccgg ttcattcacc attgcttgat gactcagcaa gtattccggc
    16021 tgctccatcc cgtggtagat tcctgacaaa gatcgatagt ctggcactcc agaaggtgtg
    16081 gatacccctg caccggtcaa aaatgtaatt tgctgataag ctaatatctc ttttgctgct
    16141 tcgtctactg ttaattgttt catgttttgt cacctcactt tccattatag cccatactcg
    16201 aacaaattta ttgttgaaaa gtcagaaaaa tgggaataaa aaagtgttat gggcatttga
    16261 acaatttatc acaatgttca ctgacaaaag aatgaaaacg tgttacaata ctgctgtata
    16321 aaagtgaggt gaatcgatat gttaccattc tttatttatt ggggcgttat tctggcttgt
    16381 atcgcctggt tagcgttaag cgtttatttc tctgtttttt atcttgtacg caaagaaaat
    16441 ggaaatcttt gggcttttgc tttattcaac gtgattgccg caattgtttt agccattaca
    16501 ttagccgtat atcgaacatg gggctgggga atcacccaat actcaagttt gatttatcta
    16561 atattagcca tttatggcgt cgttgttctt ttgcaagcga tcctaggacg tgagccaaag
    16621 aaagcggcag cttaaatgat cgagatggaa ctggacacag gaaattttct gttctagttc
    16681 tttttttatt gtattacata catttttgtg tataattata ctatcgtttg caatggatag
    16741 atgattcaca ttttgattgt tttttcggta aaagtaaaga tttctatatt tatcagtatt
    16801 ttttcaaaaa acagcagtta tagattgaca aagcctctcg agtatcgtaa actttttttg
    16861 tataaataac tgaatacgag atgcctcaat caatgaggta gaggtcgcga gaatcattaa
    16921 ccctgtggag tgaagcaaac atggagaagc aggaataggg aggatcgccg aaatgtgcac
    16981 ttttttgctt ggagtgtatg ttgggacgca agttaagagc ttgcggactg tcttagcagt
    17041 gatgctaagt tgcgctatgt tttgtgagag gtttatcacc ttatggaatt ttagcggcct
    17101 ttttatatct ataaatcggt cgctttttat tttttcagat aaagctttac cgcatttcat
    17161 ctagaccgct cgtgtatcat ataatcagaa agggagaaaa aaatgaaaaa aaatatggtt
    17221 tcagttgccg tactatttgc ttttgtcttc tcactattca gtgtgggatc tctggcaaat
    17281 gcagatgaaa aaacaccgag cgatgagttt cgcgtaggta tggaggctgg gtatgcaccc
    17341 ttcaactggt ctcaacaaac agatgagaat aatgccttgc caattcaagg ccaaaatagt
    17401 tacgccggcg gttatgatgt tcaaatcgct aaaaaagtag cagatggttt agggaaaaaa
    17461 ttagtcatcg tccaaacgaa atgggatggt ctggctcctg cccttcaatc aggcaagatc
    17521 gacgcgatca tcgccggaat gagccctact gctgaacgac gaaaagaaat tgattttacc
    17581 gatccttatt acgaatcaca attagtagta gtagttcaaa aagatagcaa atatgcaaaa
    17641 gcaaaaagtt tagcagatct ttctggagca aagattactg ctcagttaaa tacattccac
    17701 tatactgtga tcgatcagat accagatgtg cagaaacaac aagcaatgga taatttctca
    17761 gcaatgagaa cagctttagc ttctggaatg atcgatggtt atgtcagcga acgtccggaa
    17821 ggtgtaacgg caactagtgt gaacaaagac ttggaaatgc ttgaattcag cggtgcagat
    17881 ggcttccaga caaacccgga agatgttcag atttctgttg gtatgcgtaa aggcgacccg
    17941 gatatccaaa aagtaaacca gattctttct ggcatctcta acgatgaacg aaccaaaatt
    18001 atggaccaag cagtcaaaga tcagcctgct gcaactgata gtgaagaaaa acctggcatc
    18061 atttctgatt tcactacgat ttggaaacaa tacggcaata tgttcttacg aggtgctgga
    18121 cttaccttgt tcatcgcatt gatcgggaca gttgtcggta ctacacttgg attactgatt
    18181 ggtgtcttcc gttcggtacc tgaatcagga aatgcactga ctcgcttctt ccaaaaaatc
    18241 ggaaatgcac ttctttctat ctatgtcgaa gtattccgcg gaacaccgat gatggtacaa
    18301 gcaatggtca tcttctacgg tctggcactc gcttttggca tttcattgaa ccgaacgatt
    18361 gccgctttgt ttattgtctc tctcaatact ggagcttaca tgacagagat cgttcgtggg
    18421 gggatttttg cagtagatga agggcagttc gaagctgcgc aagccattgg tatgacccat
    18481 ggccaaacga tgagaaaagt tgttattcca caagttttac ggaatatctt gccagcaaca
    18541 ggaaatgagt ttgttatcaa tatcaaagat acagcagttt taagtgtaat cggcgtagct
    18601 gatttgttct tccaaggaaa ctctgcttcc ggtgcgaatt tccaattctt ccaaacattt
    18661 acgatcgtcg ggatcatcta cttagtcatg acctttacga tcaccagaat cctgcgggcg
    18721 gtagaaaaga aaatcgatgg tccttcagct tataccaagc ttgaagaaat cgacaattca
    18781 aatttgcagg aataaggagg aagaatcatg aatgaaaaaa ttattgaaat caaacatcta
    18841 agaaaaagct tcggtgaaaa tgaagtattg aaagatatca gcgtaacagt caataaaggt
    18901 gaagttgtga cgatcatcgg ttcttccggt tctggtaaat ctactttctt gcgctgtatc
    18961 aatttactgg aaaaaccaac aggcggcgag atcatttata atggagaaaa tgtattagct
    19021 cctaaatata atttacctaa atatcgaacg aatctaggta tggttttcca atccttcaac
    19081 ctgttcaaca atatgaatgt cttggaaaac tgtatgtctg gtcaaacaac tgtcctgaaa
    19141 cgagataaag aaactgccaa aaaagtagca atcgaaaatc tggaaaaagt tggtatggat
    19201 cgttatatcg aagccaaacc agcacaatta tctggtggac agaaacagcg tgtcgcaatt
    19261 gctcgggcat tatcaatgaa tccagatgta ttgctattcg acgaacctac ttcggcgtta
    19321 gaccctgaaa tggttggcga agtgcttaat acgatcaaag acttagcaca tactggcttg
    19381 acaatgctta tcgtgacgca tgagatggaa tttgcaaaag atgtatctga ccgtgtcatt
    19441 tttatggata aaggtgtgat tgcagaagaa ggtacaccag aagatatctt tgtccatccg
    19501 aaagaagaac gtacaaaaga attcctttca cgtattttaa atgcttagga tcaatagctg
    19561 attgggacaa agagctgcgg tgtttaccgc agttcttttt tatgaattac tcataaaagg
    19621 taaatttctg aaaattttgg aatcttagtt gtgtttttca gaaaactctt ttaatatgga
    19681 agtaattaaa cttttttagt taggatgatt taaaaatgaa tgaagagcaa gaactgcagc
    19741 gtggactgaa aaatagacat gtccaactga tttctattgg cggagcgatt ggaacggggt
    19801 tgtttttagg ttccggaaag tctatccagc tagctggccc ttcgatattg ctcgcctatc
    19861 ttattactgg atgcatctgt tttttcatta tgcgtgcgtt aggcgaactt ctgttatcaa
    19921 acaccaataa ccattctttt ctggattttg ttgcagaata tcttggcaaa aaagcggctt
    19981 tcatcactgg ctggacgtat tggttctgct gggtatcgat tgcaatggcc gatttaacag
    20041 ccatcggaat gtatgtacgc tactgggcgc ctggtgttcc tcagtggctt cctgaactga
    20101 ttgcattagg tcttcttctt tgcttgaata tggtggctgt ctcattgttt ggtgagttag
    20161 agttttggtt tgcattgatc aaagttgtag cgatcattgc ctttatcctc gtaggagctt
    20221 atatgatcct cacccactat acgacagata ttggcacagc cagtatcacg aatctatggt
    20281 ctcatggcgg attctttcca actggtgcaa aaggatttat cttagctttc caaatggtaa
    20341 cctttgcttt tgctgggata gaattagttg gattagtcgc tggagaaaca gaaaatcctg
    20401 aaaaagtgtt gccggaagct atcaataata ttcctatcag gatcatctta ttttacttag
    20461 gatctctttt tgtcattatg gcaatctatc catggaacag cttgaatcca gataacagtc
    20521 catttgtaga agtattttcg gaaattggga tcacgattgc tgcttccttg atcaatttag
    20581 tcgtattaag tgcagcagct tctgcctgca acagtgcaat atatagtaca ggacgtatgc
    20641 ttcgttcttt agcgcaagaa ggcagtgccc ctaaaaaatt caaaaagtta acaacacatc
    20701 atgtgccagg gaatgctttg acattttcta ctatcgtcat tttcatttct gttatcttga
    20761 attacgtgat gcctagtgaa gtattcacac tagtaagcag tattgccact acttgtttct
    20821 tgtttatctg gagtatgctt gtctacacgc acatgaaata tcgtaaaagt atcctcggca
    20881 aaaaagctca ttcatttaaa atgccgttgt acccatttag taattatctg gtatttcttt
    20941 acatggcctt tgtgtgtgtc gtcttgttcc taggaaaaga tacgagaatc gctttattac
    21001 taacacctgt gtggttcttg cttctattac taatctatca tatgaaatat gaacgtaaga
    21061 agtaagaaag tagttgtgac agaagtggtc agcttcgaga aataagaagg aatttacgaa
    21121 aattgcttct taaatttttg tgaaatttcg gcttatttct tggagttaaa agcttctgtc
    21181 ccagcctctt ttctatttcc ccggaaacaa ccgctgataa taggcatctg cttttttata
    21241 ggaaaaaatc caaataccag atacaaaaaa acgtccgaat aacccgatca acggtacaaa
    21301 aaagacaccg gcaatcaagc ataagttaat catcatggag ataagacttc gacggtcctt
    21361 tgacaaaact ctcacgacat gggaatctgg tttatttgct ttcatgattt gcctcatcaa
    21421 gataccaaaa gaaaaactcc acatcgtgta tactaagaca taagccatct caggccaaaa
    21481 agcttcaggg ttacgcccga cccaactagt aacagaagga cataaagtca gccaaaagag
    21541 caaaaagata ttcgaccaga ccactcggta attaattcgt tctgccatct gaaatatacg
    21601 atgatggttc acccagatca ccgcaacaaa tataaagctg atggtataag ctaataatgt
    21661 atttcggatg acccataaag aatgaaagct agatgtatta gggatcttga tctctaatac
    21721 aagaactctc aaaacaatgg ctaccactcc atcagtaaat gcttctaatc tcgactttgt
    21781 cacgatgatt cctcctcaga tgattcagcg cttttatttt atcacttacg ttattaaata
    21841 accgtcgttt tatataggaa attttctgaa aattgttgca tatttttcga aattttgtta
    21901 cttttaaaaa aaccgtaaag gagttatgta tgacaaaaaa attatcattt aaagactatc
    21961 tttttatagg ctccatgctt ttcggtctat tttttggtgc tggaaatctt atctttcccg
    22021 ttcatttggg tcaagaagca ggcgctgcta ccttttgggc gaatctaggt ttcttggtta
    22081 ccggtatcgg tcttcccttc ttaggggtga ttgccattgg tgtatcgaaa agctcaggtg
    22141 tatatgaatt agcaaaacgg ataaatcaaa catatgcgat ggtttttacc atcttgcttt
    22201 acttagttat cggaccgttt tttgctttac ctcgccttgc aaccacatct ttcgagattg
    22261 gtttagcacc atttatcgat cctagcagac agacgctata tctagcaatt ttcagtattg
    22321 tattttttgt gctggcttgg tggttttcaa gaaaaccgac aaagatatta gattatgttg
    22381 gaaagttcct gaatcctgca tttttggttt tattaggtgc tttgcttctc cttgcttttt
    22441 tgaatccact aggttctgta aatcaagcgc ctattcagcc aaattatcaa gagcatgctt
    22501 ttttcacagg gtttactcaa ggatataaca cattagatgc gcttgctgct ttagcatttg
    22561 ggatcatcat tgtcacaaca atccaaaaca tgggtgtaac aaaacctgct gaaatcgcta
    22621 aagacacgat caaatctggt gcgatcagca ttatattgat gggaatcatt tatactttgc
    22681 tcgcttattt aggtgctatg agcttaggta gctttgctct aagtgaaaat ggcgggatca
    22741 cgctggctca gattgctgat cattatttag gtacttatgg cagtatctta ttagcattta
    22801 tcgttatatt agcttgcttg aagaccggta ttggtttgat tacagctttt gcagaaacat
    22861 tcacagattt gtttccgcaa agaaattacg cattctttgt tgcacttgct agtatccttc
    22921 cttgtttagc ggcaaacgta ggcttgacga atatcattca attttcgttg cctgttttga
    22981 tgttcatcta tccattagca atgacactga ttttactagt gttagttggt cctttgttta
    23041 agcagcgtac ggctgtttat cgaatgacta cttattttac attgattgct tcgatttttg
    23101 atgggttgaa cgcttgccca gaaactatca aacaaacacc tattgttcaa aatcttttat
    23161 atgttgcgga aagctacttg ccgtttttca aattggggat ggggtggatc gtaccagcag
    23221 ttatcggttt tgttatcgga ctgatttgga gtttcgctaa gaaagaagaa gtagcagatt
    23281 gataaaagag gttgtgaaag agacgttcag ccttattgcc gataggctgt ctcttgaaca
    23341 ctgtttattg agaggtcgtg aaaaagccgc tcagtttcga gtattaagaa atattttttg
    23401 aaaatggctt ctcacatttt tgcataaatt tgacttaata ccgagaaact ggcttttgaa
    23461 caccgtttat tgagcgtcta taaactgacc tgagtattag agaaacaaaa cggcaaagta
    23521 gctccatata ctttgccgtt ttgttttgaa ctaataccga agagaagctg atcaaacaac
    23581 atttctttta taatatagat tttagacata tatatgatat aaaaatagtt ttcgcaaaaa
    23641 aa
//
LOCUS       DADLIO010000042        23147 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.042, whole genome shotgun sequence.
ACCESSION   DADLIO010000042 DADLIO010000000
VERSION     DADLIO010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23147
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.042"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            363..731
                     /locus_tag="JOX41_001772"
     CDS             363..731
                     /locus_tag="JOX41_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAY6449516.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            911..1852
                     /locus_tag="JOX41_001773"
     CDS             911..1852
                     /locus_tag="JOX41_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HAY6449517.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            1921..2652
                     /locus_tag="JOX41_001774"
     CDS             1921..2652
                     /locus_tag="JOX41_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HAY6449518.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            2796..4976
                     /locus_tag="JOX41_001775"
     CDS             2796..4976
                     /locus_tag="JOX41_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HAY6449519.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            4996..5478
                     /locus_tag="JOX41_001776"
     CDS             4996..5478
                     /locus_tag="JOX41_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HAY6449520.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            5494..6255
                     /locus_tag="JOX41_001777"
     CDS             5494..6255
                     /locus_tag="JOX41_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HAY6449521.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            6386..7720
                     /locus_tag="JOX41_001778"
     CDS             6386..7720
                     /locus_tag="JOX41_001778"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HAY6449522.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            8027..8512
                     /locus_tag="JOX41_001779"
     CDS             8027..8512
                     /locus_tag="JOX41_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HAY6449523.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            8505..9188
                     /locus_tag="JOX41_001780"
     CDS             8505..9188
                     /locus_tag="JOX41_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HAY6449524.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            9314..11959
                     /gene="polA"
                     /locus_tag="JOX41_001781"
     CDS             9314..11959
                     /gene="polA"
                     /locus_tag="JOX41_001781"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HAY6449525.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            12004..12840
                     /gene="mutM"
                     /locus_tag="JOX41_001782"
     CDS             12004..12840
                     /gene="mutM"
                     /locus_tag="JOX41_001782"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HAY6449526.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            12804..13433
                     /locus_tag="JOX41_001783"
     CDS             12804..13433
                     /locus_tag="JOX41_001783"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HAY6449527.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            13485..13817
                     /locus_tag="JOX41_001784"
     CDS             13485..13817
                     /locus_tag="JOX41_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HAY6449528.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            14129..14620
                     /gene="nrdR"
                     /locus_tag="JOX41_001785"
     CDS             14129..14620
                     /gene="nrdR"
                     /locus_tag="JOX41_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HAY6449529.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            14643..16016
                     /locus_tag="JOX41_001786"
     CDS             14643..16016
                     /locus_tag="JOX41_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Replication initiation and membrane attachment"
                     /protein_id="HAY6449530.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            16016..16942
                     /gene="dnaI"
                     /locus_tag="JOX41_001787"
     CDS             16016..16942
                     /gene="dnaI"
                     /locus_tag="JOX41_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HAY6449531.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            17071..17511
                     /locus_tag="JOX41_001788"
     CDS             17071..17511
                     /locus_tag="JOX41_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HAY6449532.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            17655..18356
                     /locus_tag="JOX41_001789"
     CDS             17655..18356
                     /locus_tag="JOX41_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HAY6449533.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            18353..19474
                     /locus_tag="JOX41_001790"
     CDS             18353..19474
                     /locus_tag="JOX41_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HAY6449534.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            19489..20721
                     /gene="pepT"
                     /locus_tag="JOX41_001791"
     CDS             19489..20721
                     /gene="pepT"
                     /locus_tag="JOX41_001791"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HAY6449535.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            20853..21761
                     /locus_tag="JOX41_001792"
     CDS             20853..21761
                     /locus_tag="JOX41_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HAY6449536.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            21796..22068
                     /locus_tag="JOX41_001793"
     CDS             21796..22068
                     /locus_tag="JOX41_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HAY6449537.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            22079..23125
                     /locus_tag="JOX41_001794"
     CDS             22079..23125
                     /locus_tag="JOX41_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HAY6449538.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
BASE COUNT         7795 a         4036 c         5076 g         6240 t
ORIGIN      
        1 agaaagaggt cgtgagcctg ccgtttcact ctgagtcaca aagagcaatt tcaaaaaata
       61 gcttctcatg tttgttgaat attgtgtctt gtgaccgagg agttgtcagg agaacaccgt
      121 ttaccagagg ttgtgacttg tttttagtca cgacctcttt ttttatttat tccatataaa
      181 tacacattat ttattccgaa aagtgaaagc gcaaataaca aaaacaacca acttatttat
      241 tattaaagaa aagcgtattt aagtaggacg attctgttga gagctttcgt agattttccc
      301 attttcctat ggtaaactga caaagttgag aatgttagaa cagatcgttt aggaggaaac
      361 agatgtttac gaatgaaata aaaatcatgc tttatgtgga cgatgtagaa aaaaatgcaa
      421 cgttttggag agcagttggc tttgcggaaa aagatcgtca agaaatggat gggacgctta
      481 taattgaagt aggagttgag gacagtcaaa cctcatttct gttatatgat cgagcatttg
      541 ttgagtccca ttcacctggc acagctacta gtgccccatc tttgatgttt tacagtaaag
      601 atatctttgg actatataaa aaaatgcaga cgcaatcagt cacattaggt gatatggtac
      661 agcttggaga agaatatgtc tttaactttg ctgatcccga tggcaactac tttgcggtta
      721 caggtaaata atagaaataa agactttgtt tttctgtgcg aaacaggaaa gcgaagtctt
      781 tttaattcaa ataataatat tatgtaaaca aaaaactttc catgcgtaat tatacacaag
      841 caaataaatc gtcaaatgcg aacgccttct ttatactgtt taggaacgaa aagaaggaag
      901 gaagaaatac atggattatc aagtactgct ttattacaat tatacaaaaa tcgaagaacc
      961 agaggaattt gccaaaaatc atttagcctt ttgcaaatct ttggatctta aaggtcgtat
     1021 tctagtagct gaagaaggaa taaatggtac tgtgtctgga accgttgaaa acacgactgc
     1081 ctatatgaaa gcaatgaaag ctgatcctcg atttgctgat acgatgttca agatcgatcc
     1141 aagcgaagga catgccttta agaagatgtt tgtaagatac cgtccagagc ttgtaagttt
     1201 aaagctagaa gaggacattg atccaaacca agtgacaggt gcctatcttt caccgcaaga
     1261 atttaaagaa gctattttag atgaacagac agtggtgatt gatgcacgga atgattatga
     1321 atatgacttg ggacattttc gaggggctgt acgcccagat atacgcagtt ttcgagagct
     1381 tccagactgg atccgcgagc acaaagaaga atttatggaa aaacgggtag tgacctactg
     1441 tactggtggc attcgttgcg agaagttttc tggttggctt gtccgtgaag gattcaaaga
     1501 tgtcggacag ctgcatggcg gtattgctac ttatggtaag gatcctgaag tccaaggaga
     1561 attatgggac ggcaagatgt atgtgtttga tgaacggatc gctgtcgata tcaaccaagt
     1621 agataaacaa atcgtcggtc gcgactggtt tgacggaaca ccatgtgaac gatatatcaa
     1681 ttgtagcaat cctgagtgca atcgtcagat tcttgcttcc attgaaaatg aagaaaaaca
     1741 tttaggagca tgtagcatag agtgtgcgaa acatccgcgc aatcgctatg ttcaagacca
     1801 tggaatctct ccagaagaag cagaactgcg gtttacagct ttaattaaat agaaaacaat
     1861 agttttgatt gtcgaccatt tccaatatgc gctatactag cgttgaggat ggtgatccac
     1921 atgaaatcat tgatttatgc tattggggat gtccatggca aacatgagct ttttgaaaaa
     1981 cttattcact attatgatcc aaagatccat cagcttgttt tattagggga tctcaatgat
     2041 cgaggtcctc gtacaaaaga atgtttttta ttaggaaagc aattagtcga agaaacagga
     2101 gccatttacc tccggggaaa ccatgaagaa tattttttgc aatttctgca atcaccggag
     2161 gactggtatg cgccttatat gagaaatggt ggaaaagaaa cgtttgaaag cctgattcac
     2221 ccaggggcat cggaggaata ctccccaact gaaatctcga tgatgatcca atcgagatat
     2281 tcagaactga ttaaattttt agtccagcgc cccttgtatt atgaatggga aaattatctt
     2341 tttgtccatg ccggtgtgga tttgacaaag aaagactggc gtaagacaag tctaagagac
     2401 tttatttgga taagggaacc atttcatgaa gggaaaaaca atacaggtaa gacaattgta
     2461 tttggacata cgattacacc aatgctccat ggagatatgc agacaacaga cctctggatt
     2521 caggatcata aaatcggaat ggacggtggg gctgtattcg gagggtcatt gcatggggtt
     2581 gtttttgaca aggaaggtat tcttcaagat attgaatatc agaacaacga aggaccttgg
     2641 catggaatct gactaatgga aagaatgaag gagctgtgac tttgttgcgg ctctttttat
     2701 ttttatagag aatattgttt ctttcagtag tttaacccag gataaaaagt atgatagaat
     2761 aaagaagcaa tttttagcag aaaagaggca ttttaatgac ggaaaatttg aaccagacga
     2821 tcattcagct tgtacaaaaa gaactttcag actatcgtcc taagcagttg actactgtac
     2881 ttaatttgtt aaatgaagga aacactgttc cttttatcgc gcgttaccga aaagaaatga
     2941 ctggaagtct tgatgaagtc cagattcgtg aaatcgaaga gcggtatgcc tatcttgaaa
     3001 acttagaaaa acgtaaaact gaagtgattc ggctaatcga tgaacaaggg aaactgactc
     3061 ccgagttaga agcagaaatc acccaagccg tgaaaatgca acaagtggaa gatttgtatc
     3121 gtccatacaa acaaaaacga cggacaaaag caacgattgc taaagaaaaa ggacttgaac
     3181 cactcgcgaa gtggctgatg cagcttacag atggagaggt gcaatctgaa gcagaaaaat
     3241 atattgacaa agaaaaagaa gtctcttctg ccgaagaagc gttgcacggt gctcatgaga
     3301 ttattgctga acaagtcagc gataatgcaa aatttcggac ttggattcgg tcttatacgt
     3361 ataacaaagg tatgtatgtc agcaatgtca aggatgagca agcagatgaa aaaggcgtat
     3421 atgaaatgta ttatgacttt gcagaacccg tccataaaat ggtttctcat cgaatattag
     3481 ctactaatcg tggagaaaaa gaagatattc tgaaagtatt ctttcaagta gatgaagcag
     3541 caattttagc ttacttggat cgccaaatag tcaaaaatcc tgcctctcct tcttcttcat
     3601 tcgtcagaga agcctatcag gatagttata aacgctttat tcagccagca atcgagcgag
     3661 aactgcgcaa tgaattgact gaaaaggcag atgagcaagc aatcgctatt ttcggcgaaa
     3721 acctccgtaa tcttttgttg caaccgccac taaaaggtaa agttgtcctg ggatttgatc
     3781 cggcttatcg tactggatgt aaactagcag tcgtagatgc gacagggaaa gttttagcaa
     3841 tcgaagttat ttatcctcat aaacctgcag cgcaagcaaa aagagaagct gctggaccag
     3901 cttttatcca attaattaat aaatatcaag tagatatggt agctatcgga aatggtacag
     3961 ccagtcggga atctgaactt tttgtggctg agcagttgaa atccgccgac cataaaacct
     4021 attacgctat cgtcaacgaa gcaggcgctt ctgtttactc cgctagcgaa attgcacgaa
     4081 aagaatttcc gcatctacaa gttgaagaaa gaagtgctgt ttctattgcc cgtcgcctgc
     4141 aagatccttt agctgaatta gtcaaaatcg atcctaaagc tgtcggagta ggccagtacc
     4201 aacatgacgt ttctcaaaaa cgtttggctg aacaattgga ttttgttgtg gaaacagcgg
     4261 ttaaccaagt aggtgtggat gtgaatacag caagcccgca gctcttgcag catatatcag
     4321 gattgaataa aacaactgcc caaaacattg tcatttatcg tgaagaaaac ggagaattca
     4381 ccgcacgaac tcaattgaaa aaagtgccac gcttaggacc aaaagcatat gaacaagcaa
     4441 tcggattctt gcgagtccct ggtgggaaaa acattttgga caacacaggt atccatcccg
     4501 aaagttattc tattgcaaaa gaaatattaa cttcagtcca actttcagaa aaagagcttg
     4561 gtacagaaga agcagtagaa aaattgacac gattatccgt agagaaactg gctgaaagcc
     4621 tatcagtcgg agaagaaacg ttagccgata ttttagctgg gctgacacaa cctggacgag
     4681 atatgcgtga tgagatgcca gcgcccttat tacgtacaga tgtattgagt atggaagact
     4741 tgaaaccagg gatggaattg actggaacgg tccgtaatgt cattgacttc ggcgcatttg
     4801 ttgatatcgg tgtgaagcaa gacggacttg tccatatatc gaaactcagc aaaaaattcg
     4861 tcaagcatcc tacagatgtc gtgtcagtag gagatatcgt aacagtttgg atagaacaag
     4921 tcgatacgaa aaaaggcaga atcagtttga cgatgctttc cccttatgaa gagtaacaat
     4981 gaggagtaac aaaaattgac acaagaagaa ctgcagcagt tagtagaaga gatatcatta
     5041 aaaagcttcc agcttccttt caagcaccaa gcaatgttca atccacgctt acgtacaact
     5101 ggcgggcgct atcatttaaa cgatcatcat ttagatttta atgcgaagct atttgaagag
     5161 tcagacgaag agacgattgc aggaatcatc aaacatgaac tttgccatta tcatcttcat
     5221 ctagctggaa gagggtatca gcataaagat atggatttca agtatctttt gaaaaaaaca
     5281 ggagggttgc gctatgcacc agccttgacg aagaaacaga taaagatgga gtattatcga
     5341 tgccaagatt gttctgccac gatctgccgc aagagaagaa tcgatgtacg caaatatcgt
     5401 tgtggaagat gtcatggaga aatcaaatgg attgagacaa aaagagaaga ctttaatgaa
     5461 gcacaaaaaa tcagatgaaa ggatagaagg cctttggaaa aaagtgagca gaggaatcta
     5521 aaagactgga atcagctatt aaatttttta gccgcacctg aagagggaaa ttttgaggaa
     5581 ctgacggcac ctacacttat tttagctgga aactgtcttc ctatcttagc tgataaagca
     5641 gcacaaatgt atttaaatgg ccaagtagat caattgtttt tggtcggagg ggtggggcat
     5701 gcgactagaa tcctttatga gaattttgaa aagcaaggat ttcattttga agatggcatg
     5761 agtgaaagtg aaatctgtcg tcagtatcta aaagaagtct atgatttgcc cgataaggct
     5821 tttctgatag aatcgaagtc tacaaattct ggagagaacg ccactttttc actggagatt
     5881 cttcattcct taggagctgt accagaaaaa atcttattga tgaatgatcc gacactgcaa
     5941 cgcaggactc gagcaacttt tgagaaagta tggcaaaatg aacaaactat tttcgcgaat
     6001 gctgtgccat ttgtgccgga aatccttcac ttttctgaag agatcatctt tacagcaaaa
     6061 gaactgaatc atcaatggcc taaggaatat ttccatgcgc tagtattagg agaaatggaa
     6121 cgtctccatg acgatgagaa cggctatggt ccgaaaggaa aagattttat tcctcacatt
     6181 gatatatcag aggaagtttg gtcttcttac accagaatta aagagtcaat aaaaacggat
     6241 ttttctcgta cttgaccatt ttagcaagcg aatcctcctt tccaaataaa tttggttgaa
     6301 attttcaatc gtttataaga taatgaggag cgtgttgaat gtaatagcta aaagaatgga
     6361 cgctagataa gagaagagga ttcaaatgga aaatcaaaat aaattgtatc attttgttgg
     6421 tatcaaaggt tcaggaatga gctccttggc tcttgtttta catgaacaag gtctaaatgt
     6481 ccaaggatca gacattgaaa aatatttctt tacacaaaga gatttagaaa aagcaaatat
     6541 cacgattctg ccatttaacg cagataatgt aaaaccaggg atgacgatca ttgcaggaaa
     6601 tgcatttcct gattcacatg aagaaatcca gcgagcaaaa gaattaggtt tggaagtgat
     6661 tcgctatcac gactttattg gtcattttat ccaaaattat acgagtatcg ctgtaacagg
     6721 ctctcacgga aaaacaagta cgactggact gctctctcat gtattgagtg gtgtccgtcc
     6781 aacaagttat ctaattggag atggaacagg acatggtgat ccgcaagcgg aattcttttc
     6841 atttgaggcc tgtgaatatc gccgtcattt ccttgcctat tcaccagact atgcaatcat
     6901 gaccaatatc gattttgatc atccggatta ttatacaagt atcgacgatg tatttacagc
     6961 tttccaaaca atggctggac aagtgaaaaa agctattttt gcgtatggtg acgatgctta
     7021 tttacgcaaa ttaaaagcaa atgtgccgat ttattattat ggtgtcacag aaaacgatga
     7081 tatccaagca cgaaacatcg aacgcacaac ttctggttct gcttttgatg tctatcatgg
     7141 ggatgaattt gttgggcact tcactgtacc agcattcggt aaacacaata tcttaaatgc
     7201 tttaggtgtt attgcagtag cttatttcga aaaactggat ctgaaagaag ttgcagaaga
     7261 aatgctgact ttcccaggag taaaacgtcg attcagtgaa aagatcgtag cagacatgac
     7321 cgtagtcgat gattatgcgc atcaccctgc agagatcaaa gcaacgattg atggcgcacg
     7381 ccaaaaatat ccagataaag aaataattgc agttttccaa ccccatacgt ttacgcgtac
     7441 gattgcattg atggatgaat ttgcagaagc acttgattta gctgataaag tttacttatg
     7501 cgatattttt ggttcggctc gggaagaaca aggaaacgtt aagattgaag accttggagc
     7561 gaaaatcaaa aaaggtggag aagtcatcaa agaaaataat gtatctccat tgttagatta
     7621 tcatgatgca gtagtaatct tcatgggtgc tggagatgtt caaaaatttg aacaagcgta
     7681 tgaaaaactt ttaagcagca cgacgaaaaa tgtactgtaa tacaattact gcagtgtcct
     7741 tataaaaata gaaagagggg gagtggcaaa aatcttgcca agcccccttt tttgcaactt
     7801 atgataaacg gtgttcaaaa gcttgcatct gcggtaataa gcccaatcaa atcaaaaaca
     7861 tgagaagctg ttttttcttg gctgttctta ttatttgatg caggacagct ttttcacgac
     7921 ctctgtaaac tataggaatc tgttaaatca agggagcaga acttgccttt tacgctactt
     7981 ttggtacaat aatgtatgat taaaaataaa ctggagggtt tctatcttga acataggtaa
     8041 gccgagaaaa ctaggaaaaa caataaatga aatcgaggaa ggcgactcgt tatccttaac
     8101 agaatctatt gaagataacc agcttttgct gtatttggga ttgacgaatg atgcaaatcc
     8161 tttgtatatc caacatgact ttgcacaaaa aacagaatat caacagccaa tcgttccatc
     8221 agtgatgctg atggggatca tcacaagtgc aatttcaaag catcttcctg gaccaggatc
     8281 acatgttgtc aatttttctg tcaattttat tgaaccggtt ttccattatg aaacactgac
     8341 ttttcagttt gaggtcataa aagtagataa gatgaaggat gtggtgacga tttctgtaga
     8401 agcggagaat acgaacgaag atcgtgtgtt ggatgctgtc gttatggtcc aaccgccaca
     8461 agttcctgaa ttggaaatag caatcgaaag tgaaggtgaa ttgaatgaat aatccaagta
     8521 catcaatgtc aggtatcaat cgtttttatg caaaagttta tggattttta ggtatgggac
     8581 ttgcccttag tgcagtcact tcttacttgg ctctttgggt atttcctttg caattagcaa
     8641 cttttatcaa taattttcca ctaggctttg tgggtctgtg gatcgttgaa ctgattttag
     8701 taatggttct aggcgtaaaa gcacaaaaga atccgagctt agcaatcggt ggatttattg
     8761 cctactctct tttgaatggc ataacattag cggttactct tgcatactac gatattggaa
     8821 cagtaacgca agctttcttg acagctactt tgatgttcat ggggatgtct gttgtcggag
     8881 taacaacaaa aagagatctt agcggggttg gaagagcagg acaggcagct ttaatcggag
     8941 tgatcattgc actagtcttg aacatcttca ttttgagaag tagcgtagtt gagctgttca
     9001 tctccctact gttagtcgtc atctttgcag ggattacagc ttatgataac caaagcatcc
     9061 gtaatatcta tgtccagaca aacggaacag cacatagtgg aattgctgta ttcatggcat
     9121 tgaagctgta tttggacttt atcaacttgt tcttggcgtt tctgagaatc tttggacgga
     9181 acaactaaaa aagaaaaaaa ttcatcagtt ggggctatac cgaattattt ggtatggtcc
     9241 cgctttttct tttcgcattc cgcaggattc tttgttagaa tgaataagaa ctttacagta
     9301 aggagttaag aagatgacaa aaaataaatt attactcgtt gatgggaaca gtgtggcttt
     9361 tcgcgcattc tttgcgcttc acaattctct tgaacgtttc aaaaatagaa acggtcttca
     9421 tacaaatgca atctatgcat tcaatacgat gtttgaaaat gttatgcaaa aagagcaacc
     9481 gactcatgtt ctggttgcgt tcgatgcagg aaaaacgact tttcggacag aaatgtatgc
     9541 ggagtacaaa ggtggaagat ccaaaacacc tggcgaattc aaagaacaaa tgccatatat
     9601 acgtgatttg ttgacaggac taggggtaca gtattacgaa ttgcccaatt atgaagcaga
     9661 tgatattatc ggtactttgg cagaaaaagt agacaaagat caatttgatg tcgtcgtgct
     9721 ttcaggtgat cgggatttga ctcaattagc tagtaaagaa gtaaaagtgg atatcactgt
     9781 aaaaggtgtc agcgatatcg aaagctatac accagaacat gtagcggaaa aatatgatgg
     9841 gttgacgcca aaacagatta ttgacatgaa gggactagcc ggagatgcct ctgacaatat
     9901 ccccggtgtg actaaaatcg gtgaaaaaac agctatcaag ctattgaaac aatatggctc
     9961 agtcgaagga atttatgaac atatcgatga aatgaagcaa agcaaaatga aagaaaatct
    10021 gataaatgac aaagagcagg ctttcttatc gaaaaaattg gcgaccatca atacttcagc
    10081 gcctgtggat gtctctatcg actcattgaa gtatgaaggg aaaaatctcg ataaactcgt
    10141 tccgttttat aaagaaatgg atttcaatca gttcctttct aaattgaata tcgtagaaga
    10201 agaagtaaaa atggatgata ttttgtttga agtcgttcat gaattcaaag aggaaatgtt
    10261 tactacggat atggcgttgt acgtggaaat gatgggcgac aattatcata cagaggaaat
    10321 cgtcggagta gcgtggggga cagaaaagaa aatttatgtc acgaacgatc tatctgtatt
    10381 cgaaaaccga gcgttccatt cttggatcac tgatccgact cggctgaaaa aagtatatga
    10441 tgcgaaacga acttatgttg ctttaaaccg ctatactgga aaaacgaaag gaatcgattt
    10501 tgatgtcttg ctaggtgcat accttctcga tacgaatgaa aaaagcacag atatcgaagg
    10561 aatagctgct cattacggat acaacgatat ccaatcagat gaagctgtat acggcaaagg
    10621 ggcgaaaaaa ggtttaccag aagaagagga actctttttt gctcatttag cgcgaaaagt
    10681 agctgcaatc aatgcgttga caccaaaatt gagccaagaa ctggcagaaa aaaaccaaga
    10741 agatcttttc cggaaaatgg aactgccatt gtctatcatt ttggcagaga tggaaataag
    10801 cgggatcaaa gtagatgcga ctcgcttaca agaaatgaag ggcgagttct ctgctcgctt
    10861 aagagagatc gaacaaaaaa tctacgaaga agccggcgaa gaattcaatt tgaattcacc
    10921 aaagcaatta ggagtgatct tatttgaaaa aatgggatta cccgttatca aaaaaacaaa
    10981 aactggatat tccacagccg tagatgtact ggaacagctt cgtgaacaag caccaatcgt
    11041 agaggatatc ctcacctatc gtcaaattgc aaaaattcaa tctacctatg tcgagggact
    11101 gctgaaagtg atccaatcag atggaaaagt gcatacccgt tatgtccaga cattgaccca
    11161 aacaggacga ttaagctctg ttgatcctaa tttgcagaac atcccgattc gattagatga
    11221 agggagaaag atacgtcagg catttgttcc tagagaaaaa gactggctga tttattcttc
    11281 tgactattca caaatcgagt tacgcgtact tgcgcatatc tcaaatgatg aacatttgaa
    11341 agctgccttc ctagaaggtc aagatatcca tgccagcaca gcgatgcgtg tatttggaat
    11401 cgaaaaggca gaggatgtca caccaaatat gcgtaggcag gcaaaagcag tgaattttgg
    11461 tatcgtgtat ggcatctctg attacggact ttcacaaaat ctaggaatca gccgaaaagc
    11521 agcacagcaa tacatcgata cgtactttga aaaataccca ggtgtcaaag aatatatgga
    11581 aagaatcgta cgcgaagcaa aagaccaagg ctacgtcgaa acgctgtatc accgccgtcg
    11641 atatctgcca gacatcaatt caagaaatta caatatccgt tcttttgcgg aacgaacagc
    11701 tatcaataca ccaatccaag gaagtgctgc tgatattttg aaaatcgcga tgatcgaatt
    11761 ggataaacga ttaaaagaaa caggtcttca agctacgatg ctgttacaag ttcatgatga
    11821 acttgtcttc gaggtaccgg aaaaagaact tgaatcatta gataaattgg tgaaggaagt
    11881 tatggaacaa gctgtttctc ttcatgtacc actgatcact gacagcagtt ggggaaaaac
    11941 gtggtacgaa gcaaaataaa cattgtttaa gacagagcaa tataatgaag gtgaaaagaa
    12001 aaaatgccag aattaccaga agtagaaacc gttcgtaaag gattggaacg gttagtagta
    12061 ggaaaaacga ttcaaaaagt tcaggtcttg tggcccaaga tcatcgagca accagagaca
    12121 cccatctttg aggcttctct tgttggcgaa accatccaat ccattggacg tagagggaag
    12181 tttttaattt ttcatctcga tcattgtgaa ctgatctcac acttgcgaat ggaaggaaaa
    12241 tatcaattta cgaaagaaaa tacaccaatc gataaacata cgcatgtact tttctttttt
    12301 gaggatggaa gccaacttcg ctacaacgat gtacgaaaat ttggtcgtat gacaatcgtc
    12361 gaaaaaggag caagtgcaac ttaccgagga atcatgaaat tgggacctga gcctttgcca
    12421 gatagcttct tattagcaga tttcgcaaat ggactgaaaa agtcccacaa agcaatcaag
    12481 ccattgctgc tagaccaacg tctagtgact ggtctaggta atatttatgt agatgaagca
    12541 ttatgggaag cgaagatcca tccagaacaa ccggcgaaca cactgcgccc caaagaggta
    12601 gaacaattac gtctatcgat cattgatgtt ttggatcgtg caatagaagc cggaggtacc
    12661 acgattcgca gttatttgaa tgcattagga gaatcaggcg gatttcaagt agcactgcat
    12721 gtctatcagc aaactggcaa accatgtata cgttgtggaa cgccgatcgt gaaaacaaaa
    12781 gtggcacaaa gggggacgca ctattgtccg aattgtcaaa ggctaaaaat cgcaaagtag
    12841 gatttgtttt aggtttgacg ggtggaatag ctaccggtaa aagtacggca gccaaagtct
    12901 ttcagtctca tggatttcct ttgatcgatg gcgatgtgat tgccagagaa actgttgagc
    12961 ctggaacgct tgctctgagg aaaattgtat cagtgtttgg ccaagaggta ttgcagcctg
    13021 atgggcaact agatcgaggg aaacttggga tgattgtttt tccatcaaag gaaaaacggc
    13081 aaaaacttga tcagctatta gatccgttta tccgaaaagc gataaaagat caaatcgcct
    13141 ctctaagttc caatcatcct ttagtaattg tagatatccc attgctctac gaaggtcatt
    13201 atgaccacta tatggatgca gtagctgtcg tttatactac gccagaaact cagcttcagc
    13261 gtttgatgaa acgtaatcaa ctgacgctag aacaagcgca gcagagaatt agtagtcaac
    13321 ttccaatcga agaaaaaaag cagcgtgcgg atattttgtt cgacaacaat ggaacaaaag
    13381 aaaaacttgt gggacaaatc gaaaattggc tttttgctaa tcgctttctt tgagtatctg
    13441 tgtcaatttt gctatcctga gtatatagaa agtgagggat agcgatggga tcattaaaaa
    13501 atcaaaagga taaagtcgta ggtaacgcaa aagaaaaaat cggcgagatg ctcaataaag
    13561 aaaatctaat cgatgaaggt cgtacgcaat cagaaacagc agaagaaaaa gaaaagcagt
    13621 accaagcaag aatcgatgaa atagaagacc agcaggcaga agaagaagcg aagcggcaag
    13681 atttgactca agaacgaaaa aatccgacac ctgatcgtag taaaacaccg ctcccagaaa
    13741 gtgaccacat tcccgatgag caaaaaatcg aggaacagcg aatgaaacac tatacaggaa
    13801 tcgaagagaa gttataaaat agtaaaaaat cgagatgtga cttgaagcag atgagaaggt
    13861 gttcatctgc ttcaagtttt ttgtgctaga tgactaaatc agcttttgtg taagttattt
    13921 ctcagtaatc aaggtgatca gtattggaaa attgaaattt agtaaggaca ggggacacaa
    13981 ttacgcatga aagtagaaaa aattgttctt atatccgtgt tttttgggta ggacagtcgc
    14041 gtttgtgatt tgtttcgtgt tataatacaa ctagttgtaa agaaagacac atcctttata
    14101 taaaatgcga tgcaagaggt gagacaaaat gagatgtccc agatgtcaac ataataattc
    14161 acgagtaatc gacagccgtc aagcagatga tggacgtgcg atccgtcgcc gtcgcgaatg
    14221 tgagaattgt tcgttccgat tcactacatt tgaacgaatt gaagctgctc cgttattagt
    14281 aatcaagaaa aacggggaac gcgaagagtt caatcgcgat aaaattttaa gaggactcat
    14341 ccgttcagca gaaaaaagac ctgtagctat ggaacaaatg gaacaaatcg tcaaccatgt
    14401 cgaaaaccgc gtacgcagtc tcggagaaaa cgaagtatcg acgaatctaa ttggtgaata
    14461 tgtgatggaa gatttagttg atttagacga aatcgcttat attcgttttg caagtgttta
    14521 tcgccagttc aaagatatgt ctgttttctt aaaagagttg caagatatcg tggataaagc
    14581 aaaagaaaat aataaagaga ataataaaga aaacaattaa gaaacaaaaa ggaggcattt
    14641 ccttggaaaa tgcttggaaa gagcttcaac caaaaaatat ttaccaagga agaaaagcgg
    14701 ctccgctgag agaagacagc aagaacgcct tgctgtatct ttatcagcca ctaatcggcg
    14761 gagaagcctt gagtatctat ttcaccctgt tatcagaaat ctctcaagaa tctggcaaag
    14821 gtcctgaagg gatgcatgca gatctgctta gtagtctagg ctgcggtatc ccgcaatttt
    14881 atgatgcaag aaaaaagcta gaaggaatcg gcttactgga tgtttatttt aaagaagata
    14941 gtgatctggg acctcgtttt atttatgagc tgttagaacc actcattcct aaagcatttt
    15001 tcaaagactc tgttctggct tttcttcttc tggaaaaagt tggtgaacga cgattccaga
    15061 agcttaccca attctttgaa cctaaaaggc atacagcaga gggatatcaa aaaatcacaa
    15121 aaaaattttt agatgtttat cgcttcaatg aagcagtgta cgctgctaat caagaaaaca
    15181 tcgaatcgct gaataaatct tttgaagaat ctgaatcagt agcattactt gaagcagatt
    15241 cgacattcga ttggcagttt ttgaatgatt ggctggcaaa aaaacatatt gcaagtcttg
    15301 atgatccaat catcaaacaa gtcgacatgt atcatcagct ttacggtttc gatgaattga
    15361 cacttggcga actgatcagt caatcttatg actttagtga acaaaaagta tctgaaaaag
    15421 aactgcaaaa agccattttg gcaatgcaga gacgtccggt gaagcaaaca aaagaaacag
    15481 ttgcggtttc tgaaaacagt aatgaaccct cgtcaaacga acatttgaca aacgcagcgc
    15541 ttcagctgat aaaagaagca cagagcattc caccgatgaa atatctggaa gcaatcaagt
    15601 cagaaaaagg cggatatgtt tctaaacaag aaaactggtt actgcaagat cttgtttctc
    15661 aatcaggtct ttccagtagc gtgatcaatg ttttgctgaa ttatgtacta gtgatcaaga
    15721 ataatgctag cttaaatgcc agttatgtaa atacagtggc aaatgaatgg gcacaaaaga
    15781 aaatcgccac agcagaagaa gcgatccagc acattcggca aataagtaat caagcaaaac
    15841 aatcaaaaca aaagaagcaa acaaattatc aaactggcaa gcgaaatgtt cgacgggaaa
    15901 agcttcctga ttgggtcaac cagccaaaag atgaaaaaca gatcagcagc gagaaaaaag
    15961 cagagattga ccgccgtttt aaagaatacc tggcaaaaaa ggagggtgat atctagtgga
    16021 agacgtaggc aaagaattga agaggatcat cagcaaacgc aattatcaag aaaagtatgc
    16081 tgaaatgatc gctgaagtct taaatgatgc ggatgttcaa gcttttctaa gcgcacacca
    16141 agaagaattg acacaagcgg atattgaaaa aagttacgct aaattgtatg aattcgtgca
    16201 agaaaagcgt aaatatcaaa aaaacgatcc aacgatgatc gctcccggct atgagccgaa
    16261 gctgacgttg aattttcatt atgtggatgt cacttatgta ccaacggaag cattgttagc
    16321 acggcaaaga caagaagaaa tcagaagccg agtaaaagca atggatatgc caaaagatat
    16381 tcaatcggct tcttttgaaa actttgaacg tacagatgga cgaggatatg cgagcttaga
    16441 agccctagat tttgtagaga aatatactgc tgatccaaaa gggtatcata aaggactgta
    16501 tctagtagga agttttggta ttggaaaaac atatttatta ggagcaacag cgagagaatt
    16561 agcgattgct ggattcacca cgacgctagt ccattttccg acatttgccg ttgagatgaa
    16621 acaggcaatc ggaaaagatc aagtggcaga aaagttagat gcagtgaaac gttcacctat
    16681 tttgatgatc gatgacattg gtgcagatgc gatgagtagt tggatacgag acgaagtatt
    16741 cggtgttatc cttcaatatc ggatgcagga acagttacca accttcttct catcgaattt
    16801 tacaatggat gaattggaac agcatttgtc cgtcactcaa cgtggagatg aagagccgct
    16861 aaaagcgaaa cggataatgg aacgcatacg ttatttgaca aaagaaatcg aaatgactgg
    16921 tcgcaaccga cgcaatggtt gaacagttga caagtccaac tgacatttga cctagtagta
    16981 aaagcaggtc agcgaatcat tatatggaca gaaatgaccg gagacaatca ccgcaacaag
    17041 taatgcagaa acttaaacgg aggatttttt atgagggcta ttttttctag tatatctgta
    17101 gttggtctat tttttctttt agcaggctgc ggtagcgcag atagcaacac aggttctgtt
    17161 gattcgattg atgcgggtca aacagtaaaa acaagcagta cgaaaacgga gagacaaagc
    17221 atatttgtcg gaacgattga aagtatcact caagtagaag cagaagaaga aacgcttcag
    17281 ttgaaactcg tcgatgtcat ggccaaagaa gatccagcga atatgggaac gtcattcagc
    17341 aatgacggag tgatcttaaa tgctactgct gaaaaaataa gcgtggacat aaatgaattg
    17401 aaaatcggtg acaaagtcca atttacatta gttgagatgc cgatcatgac gatgtctatc
    17461 ccaccgcaag ttcctggaga ttcgattatt gatgtttcat tgaacaaata accaataaca
    17521 ttttttcaaa aataagaaaa tgttgtttta tagaacgaaa aggtatattt tttaaggaga
    17581 tatgggaatt tttttattcc tagtctcctt attttatttg gaaaatgcta taattatcta
    17641 gaaggagtga agctatgaac catttagatt tatctcagcg cttagccgca gtgggtgact
    17701 ttgtccctga atccgctcgt ttagcagaca ttggatcaga tcacgcttac ttacccgttg
    17761 cattgatatt aagaggaaaa atcgaatatg cagttgctgg tgaagtcgtt caaggtcctt
    17821 atgaatcagc acgtaagcaa gtcaaaaaag atggattaga agaccgtatc accgtacgcc
    17881 ttgcaaatgg tctagatgct atccagccac aagatggtat tacagctgtc acgattgcgg
    17941 gtatgggagg ttcactgatc cgagatatcc tagaagctgg caagttgaat caacgcttaa
    18001 gcggacaaga acgtttgatc cttcagccaa acatcggaga gcgtacatta cgatcttggc
    18061 tgcaagaaaa tcagtataaa atccaatcag aaaaaatact tgaagaaaat aaaaaaatat
    18121 atgaaatcat tgtagccgaa aaagaacaaa aaccagttac ttacaatgaa atggagctga
    18181 tgttcgggcc atttctgctt gaagagaaaa gtgagatctt caaatcaaaa tggacaagag
    18241 agcttcaaca aagaaaagct atccgtgaac agctcaaaca agcagctaat caagaggcac
    18301 gtcaaaaaca aatcgagcag gaaatccaaa tgattgagga ggttttaaag ccatgacaat
    18361 cagcggacgc actttcatcc aaaagtttga aagctattgt cctcagtggc tagctgaaga
    18421 aggagaccca gtcggactgc atatcggaac attggataag ccaatccaac gagtaatgat
    18481 gacattagac gttcgtccag aagtggtcga agaagcaatc aagaaaaaaa tcgatttgct
    18541 gattgctaaa catcctccaa tctttcgtcc tgtaaaacgg ctggttactg atcagccaca
    18601 agaaaaaatg tatgcagatt tgttgaaaca tgatattgcc gtctatgcag cacacacgaa
    18661 catggatatt atttgggatg gactgaatga ctggttttgt gaacttctcg gtattgaagt
    18721 ggagagttat ttagtaaaga ctcatgagat tcattataaa aaactggccg tttatgtacc
    18781 tgtggatcat gcacagaaaa tgcgtgaagt attagctgca gctggtgctg gtacacaagg
    18841 tgattatacc ggtacaagtt ttacctcgat tggacacggt cgatttactc cggaagctgg
    18901 tgcacaacca gcgattggga aagtagggaa gacagaacaa gttcaagagg caaaagttga
    18961 ggttattttg ccggaaacta tcgaaaaaca agtgattcaa gccatgcggt cagctcatcc
    19021 ttatgaggaa cctgcttatg atcttttcgc tatagatgaa ccagtcgaaa tgtttgggtt
    19081 aggacgagta ggtgaattgc cgcaagaaat ttctatagag gcatttgtag aacaagtaaa
    19141 agaagcgttc caactagatg gactgagaat agtccagcca aaaaatgcaa aatcctctgt
    19201 gaagcgcatt gcgatttgcg gtggaagcgg tgaaaaattt tatccgcaag caatcgccca
    19261 aagagcagat gtctatatca cgggagatat ctattatcat acggctcatg atatgcaaag
    19321 cgctgggttg attgcaattg atcccggtca ttatattgaa tcgttatgca agcaacgatt
    19381 tatcgagaaa tttgaatctt ggaaacaaga agaaaattgg gatattaact ttttcgtttc
    19441 tgaaacaaat acaaacccat ttcaatttaa ttaaaaggag agaatactat gtacgaaaat
    19501 cttttgccac gttttttacg atatgtcaaa acagaaacac gctccgatgc aacaagcaaa
    19561 acgactccat cgactcagac acaagttgct tttgcgcaag aattgaaaaa agaattagaa
    19621 gagttaggct tagctgatgt tttctataat gaagataacg gattcgttat gggaacatta
    19681 ccaagcaatg ttgatcatga agtgcgttcc attggattta tttcccacat ggatacagca
    19741 gattttaatg cagtaggagt caatccacaa atcattgaaa actatgatgg cgagtctacg
    19801 atcgtactag atgcggaaga acgctataca ttgaatacaa aagattttcc aaatttgaaa
    19861 aattatgaag gccacacatt gatcacaaca gatggcagta cattactggg agcagatgac
    19921 aaatcaggga ttgcggaaat catgactgca atggagatct tgatcaataa tccttctatc
    19981 cctcacggta ccatcaaagt ggcttttggt cctgatgaag aaatcggtgt cggagcggat
    20041 aaattcgatg ttgagcaatt cgatgtagat tttgcttata cagtcgatgg tggtccttta
    20101 ggtgagttgc agtatgaaac gtttagtgct gctcaagcaa atattacgat ccaagggaaa
    20161 aatgtacatc cagggacggc aaaagataca atgatcaatg ctctacagtt agcaatcgat
    20221 tttcataatc agcttccagc cgatgaagtt ccagaaaaaa cggaaggata cgaaggtttc
    20281 ttccatttga tggcattgga tgggaatcct gaagaagctt ctatgagtta tatcattcgc
    20341 gatcatgatc gtgaaaaatt cgaagcacgc aaagcacaaa tcacacatat ccaagaagag
    20401 ttgaatcagc gatttgatca agaacgaatc aaagtagata tgtatgatca atattacaac
    20461 atgaaagaaa tcattgaaaa agatatgagc atcgtggaat tagcgaaaca agcaatgatc
    20521 gagcttggta tctctccagt gatcgaacca gttcgtggag gaacagatgg ttcaaaaatc
    20581 tcttacatgg gtattccgac gccaaatcta tttgccggag gagaaaatat gcacggacga
    20641 ttcgaatttg tttctttaca agtaatggaa aaagcaacag acgtgattgt aaaaattgca
    20701 gaattgaaca caaagagtta aaatcgaaaa agaacagctt atgacaaggc gttcgtccca
    20761 atgatggaat gtcatctgtc taaggctaaa gggcaggaca atggaattgg ttgtcccgcc
    20821 ctcttttttg aagagtaaat aggaggtaaa gaatggaaaa gctgctagtt ttttataaca
    20881 aaagttcagg gaaagatgag ggtgagaaat tagcacgctg gtttcaagat tatgtaaaag
    20941 aaaagcagcc agaattatat gtagaactag ctgaaactgg cccatcgatt gatgatgcgg
    21001 aattagtcaa gaaagcagaa gccatagaag ctgatacttt agtaattata ggtggagacg
    21061 gcacgattca tcatatcgtc caagcgttcc aaaaaacatt atctcaatac catgtcggat
    21121 tacttccagg tggaactgtc aacaaccttg cacgtgttct tgagattccc ctcaaaaaag
    21181 aagaagctgc tgacgtgatc ctggaaggca atgtacggaa aatagactat ggtcaagtca
    21241 atgatgaagt cattatctct acactgacaa tcggaatctt agcagataca gcagtttgga
    21301 tcagtcaaga agaaaaacag cgttacggct cgtggatctt tatcaagaag ttttttaagt
    21361 tattgctgaa gaagaaaaaa tatcatttgg atttagaaac agacgaggag cattggaaag
    21421 gaaaatccca actgttgaca gtcacgatgt ctaactccgt gggcggtttt acaaattttg
    21481 acgactcagc gaccctagat gatggaaaat ttcatgtaac gatcgtacct tccttagata
    21541 ttttccgatt tattttttat ttgcctagaa tcatgagagg caaattctat acgatccccg
    21601 gcattactta tttcacagcc aaacgcatga aaatccaagc gcaggaaaaa tctgtgggca
    21661 ctcgaacgga tggagacacg acagatgatc ttccagttga attatctgtt gtatcaaaag
    21721 gattaacagt ttattcacca aagaaagaag aaaaagctta gaaatagtag ttaacagaaa
    21781 gttggaagaa gagtaatgga tgtattgtta cacaatcctt tgtggtttta ccttttcatt
    21841 gtgaattttt acttattttg tctgatgggg tatgataaac atcaggctag aactagcggc
    21901 tggcgtgttc ctgagaataa tttgatattt gtcagcctgt taggcggtgg tttgggagga
    21961 ttgatctctc gaaaagtttt ccatcataaa actcggaaaa agaagtttac tataggattc
    22021 gctgcaggtg tacttgttga tttgattctc atttattttt tccattaagg agcaggagat
    22081 gtcgtctaaa ggaacgaaaa ctaaaatcat tctgaatctg cttttgctga ttgtgatttt
    22141 tgccattatt tattatttaa tcaatcaatc atttgcagat atctttgccg aattgctgtc
    22201 taccagtgtt gttgttttgg cagcggctgt tatattaggg acagtttacc aaatcgctga
    22261 agggcgctca atcaaagaaa ttgctgaacc tttcgcgccg aattttacaa cgaaagatgg
    22321 gttcttgacc tctagctata ttgcgtttta ccgaatcgtt tcgtttggta caggaacgct
    22381 gatctcggag atttattttt ataacaaaaa aggaatgaag ctatcccagg gagcaggggt
    22441 gacagcactc catatgatta tgtacaaact ggcagtgatc acttatgcat tagctggctt
    22501 ggtcatccaa ttctctcttt tttattctaa tggtccatca atgatctggt ttatcatcgc
    22561 tggtatcctt ttgacgatcg tgattgttgc ctttttattg gcgatgtccg tcagcttgaa
    22621 tgttcaaata ttttttgtca gcttatcgaa taagttattt aaaagtgagc gtttgcggaa
    22681 atgggtggat acatgcaatc agcagatcta ctctttaagg gaaacggtcc aaaccattat
    22741 ccaagacagg actgcgctat tgcggattta tctatggaat atgttaaaac ttgtattttg
    22801 gtatgtactt ccttatttga ttctgattga aaaccatcct aaaatagatt ttctactgac
    22861 catttcgttt atcagctttg cagtagtgct ttcaggggtt attcctacgc ctgctggtat
    22921 tggttccttt gaatttgtct atttgttatt attcagacca gttgttggaa cagttgacgc
    22981 agtttcttcg cttttactgt atcgtttcag ttcctttatc ttgccatttc tctatggatt
    23041 tgtgtatgtg attgctgaac ggcgaagagt gatcaaagaa gaaataatag aagtaaaaaa
    23101 agagaataaa gaaaatcaag ggtaggtctt ttataagatc taccctt
//
LOCUS       DADLIO010000043        23032 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.043, whole genome shotgun sequence.
ACCESSION   DADLIO010000043 DADLIO010000000
VERSION     DADLIO010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23032
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.043"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(<1..2563)
                     /locus_tag="JOX41_001795"
     CDS             complement(<1..2563)
                     /locus_tag="JOX41_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449539.1"
                     /translation="MNQYVKKLIASILFVFPLLMVTSVFADVEKTSESTQSENQSFDK
                     TTFSEESITSETTESQSEAPTSNTRQEENKTSETSEVAEQTSDSSEEVQVRVVSADGY
                     SEAATTEELTQLLADESVAKIRLTQPLTLDRELEIKRDIVIDFGGLAHNFGTHHIYIN
                     ETPQSIEFQNFKGTAAHPGGLIPNIDGNAIIIAYMSDFWGNRYHFTGEIKFTGTLDLY
                     DGSKLGLIYAPRATVTLDGVSGVLDVQPVKEGMNAAPGKAYFCRSYQLNVINGSQLYG
                     PYLGKFYGFLDSGDETGSGKTAPGLHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVT
                     FKVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSRVAVSNDGKITINTATTGGFRLQG
                     DSSQIHVSSGGQISVKMAGDGDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSA
                     VRFENGTQKLTVTNGGSLKVRNAGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFT
                     VTGEKSNIDIRADSGATVDTTGDIDLNFMAGEKTYLVMVGKTGEDKTGIISGDVLNVD
                     LESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKAGVTFDNFEKDP
                     DYFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRV
                     PTNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSPVEITALTQGQTDE
                     NEGTGYNPWGEGEQGGLFEVQVPNEERLTTGDQVQIVAAKKVRGGQEVTELDSAKTTV
                     DVIPPEPAKLSTTLINAASRSITGTGEAGALVSLKKNQAVLSETTIDDTGKFVLSI"
     gene            complement(2785..3669)
                     /locus_tag="JOX41_001796"
     CDS             complement(2785..3669)
                     /locus_tag="JOX41_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HAY6449540.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPEAINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSILLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(3764..4201)
                     /locus_tag="JOX41_001797"
     CDS             complement(3764..4201)
                     /locus_tag="JOX41_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449541.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWVFYLVKK"
     gene            complement(4418..5329)
                     /locus_tag="JOX41_001798"
     CDS             complement(4418..5329)
                     /locus_tag="JOX41_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAY6449542.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(5706..6344)
                     /locus_tag="JOX41_001799"
     CDS             complement(5706..6344)
                     /locus_tag="JOX41_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6449543.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDFVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFNQETKHLTGREKRLIKRNALSFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKEQVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(6348..7118)
                     /locus_tag="JOX41_001800"
     CDS             complement(6348..7118)
                     /locus_tag="JOX41_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HAY6449544.1"
                     /translation="MIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQE
                     ISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSTYWERNILSGEIYPPLK
                     IKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFS
                     FFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIER
                     EPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            complement(7536..7952)
                     /locus_tag="JOX41_001801"
     CDS             complement(7536..7952)
                     /locus_tag="JOX41_001801"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449545.1"
                     /translation="MMTREKEAYERFILLFVERFNQAFHTDYATNIFEDFENSYSYSV
                     ISSTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNGFSLHQVLWCLLGKKKI
                     IITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGI"
     gene            complement(8003..8384)
                     /locus_tag="JOX41_001802"
                     /pseudo
     CDS             complement(8003..8384)
                     /locus_tag="JOX41_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339091.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            8510..9175
                     /locus_tag="JOX41_001803"
     CDS             8510..9175
                     /locus_tag="JOX41_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAY6449546.1"
                     /translation="MNIGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHQTLGLPIDFPSIESATESIEPTLPDEPLVIKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETVDRFNPFLKPQIGYTTLPVGYVENSIEHWVCNDIFVHGTW
                     LSFHAGEVEKGKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILIQDYDDALKRSPQEP
                     DRH"
     gene            complement(9572..11605)
                     /gene="brxL"
                     /locus_tag="JOX41_001804"
     CDS             complement(9572..11605)
                     /gene="brxL"
                     /locus_tag="JOX41_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002397592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease Lon-related BREX system protein BrxL"
                     /protein_id="HAY6449547.1"
                     /translation="MEQQEILKLSEFFPGKIVRKDLTKKIKEGANVPVYVLEYLLGMY
                     ASSLDETLVEKGVENVKNILARNYVRPDEAEKVKAKIRELGGYTVIDKVTVHLNEKKD
                     CYEAEFSNLGLKNVQISEEYPKKFDRLLGGGIWCIVSMEYWYDENDRWNSPFIAKKVD
                     PIQMPGLDIEAYKMARKEFTTNEWIDLLLRSIGMEPTQFNKRVKWLHLARLIPLIENN
                     FNLCELGPRGTGKSHVYKEISPNSILVSGGQTTVANLFYNMASRTMGLVGMWDCVAFD
                     EVAGIKFKDNDGVQIMKDYMASGSFARGKEEKNASASMAFVGNINQSVDVILKTSNLF
                     EPFPEVMGTDSAFLDRMHCYLPGWEIPKYRPDFFTNDYGFITDYFSEVMRELRKVSFG
                     DSFDKYFKLGSQLNQRDTIAVRRIVSGMMKLLYPDGRFEKSDVEEILRFALEMRRRVK
                     EQLKKIGGMEFYDVNFSYIDLEEEREEYVSVPEQGGGTLIPEGLGKPGHLYTVSYGKT
                     GQLGTYKLETQMTSGNGKFERTGINSDAGAREAMDSAYRYLRANYGSVSQSISLTTKD
                     FVVHVQDMNGIGMTKTLSLSTIIALCSVSLNKPVLPSLVILGDITIGGSMIKVDNLAN
                     CLQVAKDAGAKKVLVPMISAADIGTVPPELMGTFNLIFYQTPEDAVFKALGVE"
     gene            complement(11723..14245)
                     /gene="pglZ"
                     /locus_tag="JOX41_001805"
     CDS             complement(11723..14245)
                     /gene="pglZ"
                     /locus_tag="JOX41_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system phosphatase PglZ type A"
                     /protein_id="HAY6449548.1"
                     /translation="MTDINTQQIEEKLNQRFPNYGCRKIIFWFDSNQDFLEEIDSLVI
                     QNAKIYRLEKDAQFKTKRLLEYEDPETNYLIYAPFPRWDDKDEDNHLLSVLNYSEEFS
                     ADRLAIIMNELAIPLRFHQTVKQYRNFFNAKDRMRSFGEFSTHMTINKSETIELMIMA
                     VLLKSKSIRLNDLLRVVLKSFTESRENPLRELDKYQLTAKFWEFIQMKFGFTDSQPTL
                     EKLTMCLYLNYFYYQIDQEMPKKFKGFEILHLKANIITFMDQFMNDTRYMESFEQLSK
                     KVYQAIDGDGLLDSIEIDDLIEADVFSEIHAKILMFYAERLKASDTTTKIAGQTIFDS
                     LKQREKMHFASDYIYEYQLLKHAYYLVDKNRLCLPMNMDNLLTQYEKEMYWVDTHYRK
                     FIWNSDHIEEKQKYGQLYRLVEANYSKFLDQSGQIWNQTFEFKNRPSIRKFYNQAVMK
                     RSVKTVVIISDAFRYELGMNLERKLVREKKYSTNMASFLSVLPSVTEFGKAALLPNNQ
                     LTYNEGTEVLIDGKKTNGLSNRNAILQQRDANAVALNYDDVVKMNKAEVREVFNGKSV
                     IYIYHDQVDRTGDHSNENRVFEACDLAISEISRLINRLHNDGSIYRFIVTADHGFIYK
                     RSHVEEVDKIENPSRNEKDRVERRFILSEEEYEIIGTKNYSLGDSLGNDDTRNICVPI
                     TSSIFKKAGGGQSYVHGGSSIQEMLVPVLEITVAKGSNAKEPVAIELMTSNRRITGLS
                     TTLEFYQKNAISDVYDPASFWLYFEDEYGERISNEEIYVADSKTEDANQRFTKFVFEF
                     VNRRYTVEDTYYLVIKNQKNDLTERIKFIIDNPFAESFDFDI"
     gene            complement(14361..17993)
                     /gene="pglX"
                     /locus_tag="JOX41_001806"
     CDS             complement(14361..17993)
                     /gene="pglX"
                     /locus_tag="JOX41_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system adenine-specific
                     DNA-methyltransferase PglX"
                     /protein_id="HAY6449549.1"
                     /translation="MDKKAIKNFAVNARRKLIDEVMTKAKRLGIDESKIEDVKKIDSN
                     LQEIEKSGIRIQGKEIAQRNKLIAELKQRASVTSYSEAFQELIEEVAYTWFNRLIAIR
                     FMEVNDYLPDTYRVLSSEISGKIEPDIITDIYDADIFEELSSNEQQQVRTWKTDNSAE
                     AMDKLYQLIFIKICNQLNDYLPELFEEVEDYTELLFTASYIKKDGVIADLLSIPEDDF
                     YVQAGGQVEIIGWLYQYYNSEPHNQVVNIYKGIVKKQDIPAATQLFTTDWVVRYMVDN
                     SLGKYWLDHYPNSELRNKLKYLIPDKYAFEQATSVSNLKPEELKIIDNAMGSGHILVY
                     AFDVLMEIYLTLGYSERDAARAIVEYNLYGLEIDKRAYQLSYFAIMMKGRQYDRLFLK
                     KSLSPNLREFIDSPKVTDEYQERISELNNDKYSERWNEYKELIFDQFENGKELGSIIK
                     LVDKNNQAITKEYLGKVREYISKFNEFTNMDILYGMKEIQEKYLHILDVAEMLVDKYV
                     AVVTNPPYLNKMDKKLKKYVNDNYSDVKKDLFSVFIKLNSQMLIDNGYASFMTPFVWM
                     FISSYEKLRSFLINERNISSLIQMEYSAFEEATVPICTFTIKNSNEQDGSYIKLSDFK
                     GGMEVQKIKTLEAIHQHGECDYFYSTNQDNFKKIPGMPIAYWASDNVITDFAQGKLTN
                     DVADAKQGLATGNNNKFLRYWFEVEFNKIKFDAKTLEDAKKSRKKWFPTTKGGRFRKW
                     YGNNEYVVNWENDGDEIKNYVNENGKLKSRPQNLNYYFKKGITWSTLSSGQVSFRLQN
                     QAIFETKGSVLFSKDITDFEEIFGYVNSKLVNHFLTFISPTLDYHEGPMGKLPFLKVT
                     SERKLKKIREKVDENIDIARKDYNALETSYEFRRNILLSYMFKKDLSEAFNCLSRQLV
                     NQFNTLKSNEEELNDIFINHYSLEKELTKEVQDEYISARLPDKAREIKDFISYSIGCI
                     FGRYSLDEDGLIFAGGEWDPSRYQKFKPDTDNVLLITDDEYFKDSQIDIVNRFIDFVE
                     ITFGKETLEENLQFIADTLGGKGTSREIIRRYFVQDFYKDHLKTYSNRPIYWQLDSGK
                     QNGFKALMYLHRYTPDQLGKVRTEYLHELQKAYDNRIELRQQQISTSDNPKERNAMTK
                     EIVKIQKQLKEVREYDEKLGHLALKRIELDLDDGVIVNYDKLQRDPKTGEKFQIFAKG
                     VKEPKK"
     gene            complement(18057..21728)
                     /gene="brxC"
                     /locus_tag="JOX41_001807"
     CDS             complement(18057..21728)
                     /gene="brxC"
                     /locus_tag="JOX41_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX system P-loop protein BrxC"
                     /protein_id="HAY6449550.1"
                     /translation="MLIKDIFAKPIDRNIQGVIKVGQAKDENVQQELEEYVVTKELQK
                     HFKTIFDAYQRSINTPTDKMGVWIQGFFGSGKSHFLKIISYLLANREINDKKAIDYFK
                     EDGKIKDPLTLATMERCSQINTDVILFNIDSKSDAGGKKDKNGIVNVFLKVFNEMQGL
                     STIPHLADFERRLIKEEKFDAFKAAFEEINGAKWQEERHEFDWIQDDIKEAALKIDFM
                     SEAAIDNFLEKASGNYLISIDDFANLVKSYLDSKEADHHIAFLVDEVGQYIGGNRELT
                     LQLQTVVEDLGRICEGKAWVLVTSQEAIDHVTNFDNNSDNDFSKIKDRFATTVSLSSA
                     NADEVIKERILKKKEFANDSLALQFETVQTELKNKLLFVDSPELKLFQDAENYAEVYP
                     FIPYQFNLLGQILTEIRNHSYQGSNLSSGERSLLAMFKEAAERNKENDTTSLVSLDQF
                     YYSLERWIDTAISRVITQATNNSHIQRPTDIDNFNVNVLRILFMIKYVDQAIKPNVEN
                     ITSLMIRNINEDRLETKKRVEEALDLLIKENFVRKNLDSYIFQTDEEQEITREIKNQN
                     ITDSDLIVELSKRIFDGVLDRNSFAYEKLGMSGGNKFKNRYTFTYAQVLDQRPYKQAG
                     NAEMTVNFISPYSDLAGQEAELALKSSRNLLFVELPSDKEFKDDIAMYARMNLYLTTT
                     YSSVVKNFDAIRSEKSGELQELSASINDQLNELLKSAKFFYNGAEIQLTGSDFKAKFQ
                     SALQKMAEEVYHKLNQIDAPKEKEDILYLVKESKNEIIEDPSNEQAVQEIFNFINDQK
                     RNHLTITMKTIRDRFETKQPYGFTELDVEWCIAKLFMSGKIDLLYNNVQISRMDDPNS
                     IVMIIQKRRESEKIKIEPSAVISPKAKKLVDEIGRELFQSRNIVDENNNEHTMENFKK
                     YLKGQLDNLRSYFDLQNTYTYPSAYEYEQIKKYLEVIVQTSDVEDFFYTIKKYRDELF
                     DWAETYDKIKNFHKQNSTQKKIWENAQDKIRLIEKSRRQTSSQEIDQLIHEMKTILKK
                     ADPYSDMMKLNELIQEFIEQYNQLLELESQEILNKLTEEKQATFKLLEGKDFKDQFVP
                     IVDQEFQELKAKIEQANTIDDLVFLSLNVAEQYLIFNQRFDNEENRRRQEEQARKQIE
                     AANLIRETEKDEIDSAAKAEEIAIVKPTIQQKTVPMRTLNVHVKTIKSAADIDELTAE
                     INQKLKEQLQENTEITIQF"
     gene            complement(21753..22328)
                     /locus_tag="JOX41_001808"
     CDS             complement(21753..22328)
                     /locus_tag="JOX41_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1788 domain-containing protein"
                     /protein_id="HAY6449551.1"
                     /translation="MSLSIQEHLEKLNEVIQKEDFLLNRGLGNEVGYYIFDYDPKDEL
                     IVRDYINDISGTSVGDNYEVKVYNLYVIMLEYLEKRGFTEKAIKMEERRGLQKLVESI
                     GRLLKMDLPEEENVFFEYVDAHTPEKSVVFLTGIGELYPLIRAHSILNKMHQVFDRVP
                     VVMMYPGEYDELSLTILNTNKDDNYYRAFRI"
     gene            complement(22328..22927)
                     /locus_tag="JOX41_001809"
     CDS             complement(22328..22927)
                     /locus_tag="JOX41_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1819 family protein"
                     /protein_id="HAY6449552.1"
                     /translation="MNKKYSAGLVSKRFWFSEFKLYIQLRLEGYTDIEIKEKNEHENI
                     FFAVSSNRQKEIYQNVKRRVSQLDEAGLQLFNQLNIDNQKLVNLISILMIDDLFNEFM
                     TEVYAENLRKGNLQLTPVDYRSFFTEKRRSSEDISKWKDYTIKRLIAAYQTNLIETGL
                     VRGEKEYGRMTPILLDKRLIQWLVDKNRKDIVLALGGIL"
BASE COUNT         6993 a         4531 c         3342 g         8166 t
ORIGIN      
        1 ggatagaaag aacaaattta cctgtatcat caatagttgt ttcggacaaa acagcttgat
       61 tttttttcaa tgaaaccaaa gctcctgctt cgcctgtacc tgtgattgag cgagaagctg
      121 cattgatcaa tgtggtactt aatttagcag gctcaggagg aatcacatcg actgtcgttt
      181 tggcagagtc cagttctgtc acttcttggc cgcctcttac ttttttagca gcaactattt
      241 gcacttgatc ccccgttgtt agtctttctt cgttgggtac ttgaacctca aacaaaccgc
      301 cttgttcgcc ttctccccac ggattatatc ctgtcccttc attttcatct gtttgtcctt
      361 gtgtgagagc agtaatttct acaggtgatt tcgtcgtatc tgcataagta atacgtaaag
      421 tcacttctac ttcgcctgtc caagcatctc ttggctttgc ctcgacacct tcgggaacaa
      481 cgacatgccc atagattttt ttatctgcat tcgttggtac tcttaaggat tcaatcatcg
      541 gaagctggtt attggcactg attcgattat aatttttcat tccggcacct gtctgagcaa
      601 attcatttgt taaacctgca ctagggcttg atacaaaatt acctaagtcg gttccattga
      661 tcgataagtc tgtcatatca gaaaaataat ccggatcttt ttcaaagtta tcgaacgtta
      721 ctcctgcctt tcgccataaa gcaatttctg aatgagcgat cttcaaagaa gaatcgccat
      781 ttccttgaaa tacccagcca cctatgccat tagtctcgct tccgatccgt ttgttttgga
      841 aatcgaaata ggtaggagat tctaagtcta cattcaacac atccccactg atgatgccag
      901 tcttatcttc cccagttttc ccgaccatga ctaaataagt tttttcgcca gccataaagt
      961 tcaaatcaat atctccagtt gtatctacgg tagctccgga atctgcgcgt atatcgatat
     1021 ttgatttttc tccagtaacc gtaaaatcag ctgaccctgg actttctaga aaaccagaag
     1081 cgtcataaaa ttggatcgct tggtttcctt gattgagtct gttcacataa gatttgccat
     1141 cccctgcatt tcttaccttc aatgagcctc cattagttac tgttagtttt tgcgtaccgt
     1201 tctcaaaacg aactgcgcta gaacgaccac tttgcttatc aatatcgatg actgatccgg
     1261 ctccttctac gatcaaagaa agtcctttcc ctacaaaacg catcccattg tttccaggtt
     1321 ggtcgccatc tccagccatt ttgaccgaga tttgtccacc acttgataca tggatttgac
     1381 tagaatctcc ttgcaggcga aatccgccag tagtcgctgt attgattgtg attttcccat
     1441 cattcgacac agcgactctt gatcctgagc ctctcatttg gataattccg cgattgttgt
     1501 cgttggtaat attgatcttt gtatttaccg aaaattcact tcctgagcca ctgactttaa
     1561 atgtgacatt cccgggtagc gtatcgacag cctctccttc atcgctgacg ccatctgccc
     1621 gatcatagtc aagagagacc tttgaaccac tcaagatatg gagtcctggt gctgtttttc
     1681 cactgcccgt ctcatcacct gaatctagaa aaccatagaa ttttcctaga tatggtccat
     1741 aaagctgact accattgatt acatttagct gatagcttct acaaaaataa gctttacccg
     1801 gagcggcatt catcccttct ttcactggtt ggacatccaa tacaccggaa acaccatcta
     1861 atgtgacagt tgcacgaggg gcgtaaatca ggcctaattt agaaccatca tataagtcaa
     1921 gtgtcccggt aaattttatt tctcccgtaa aatgatatct gtttccccaa aaatcggaca
     1981 tataagcaat gataatggca tttccatcga tatttggtat caacccacct ggatgagctg
     2041 ccgttccttt aaaattctga aactcgatcg actgaggtgt ctcattgata tagatgtgat
     2101 gtgtgccgaa attatgagca agtccgccaa aatcgataac gatatctcgc ttgatctcca
     2161 attccctgtc taaagtcaaa ggctgagtta aacgaatctt agctactgat tcgtctgcga
     2221 gaagctgcgt cagttcttct gttgtggcag cttcgctgta cccatccgct gaaacaactc
     2281 taacctgtac ctcttcactg ctatcagacg tttgttcagc tacttctgag gtctcacttg
     2341 tcttattttc ttcttgcctt gtattagaag taggcgcctc actttgggat tctgtagttt
     2401 cagaagtaat tgattcttct gaaaaagtag tcttgtcaaa actttgattc tctgattgcg
     2461 ttgattcgct tgttttctct acatcggcaa aaacggatgt caccatcaag agagggaaga
     2521 caaacaaaat cgacgcaatc agctttttta catattgatt cattctccac catcctctct
     2581 gacgttttga caattttatt ttaacgtttt aatttatttg taattgtact ttcatattta
     2641 aaatatgtat ttttatggca aatttttctg ttaggtgaaa atttcttttt tgtacaaaaa
     2701 aaggctgtga caaaagtctt gtcacagtcc cttattccga acaaccgatg tcctcctgac
     2761 aactcttcgg tcacaacctc cattttaaca ataaacctgt aaatgtgagg gtaacacttt
     2821 gattgtcaca ggtaatttat ccccttcatc tccatcaaca ttcgtcgtca attcttcctc
     2881 atcagctaat gacacaacta attgctcaca agtaagatag gctagatttt tcgtagattc
     2941 atctactcct tttaataggt ctggcaatgt tttaagcgta tcgatcaaag aagaatcttt
     3001 taaataaacc aaatggagct taccatcatc cacttttgca tttggaagta atgtttcaaa
     3061 accgcctact gagttagtta gtcctatcag caagatactg ctctcaattt cttccttctt
     3121 tccatcaact tctacgtgaa acgagtagga ttgtgtggaa gctaactgtt tgattcctga
     3181 catgaaataa gctagttttc caaatttcgt cttcttctcc gcatctacat cattgattgc
     3241 ttcagggata gagccaattg cgacgacatt cataaaatag tcgtcattta tttttccaat
     3301 atccaatggc ttgactgatt caatcgaaaa atgattgatc gcttcctcag gttctagcgg
     3361 tatccctaat gctcgagcca agtcattcac cgtacccaat gggaaaaatc cgaaatttgg
     3421 ccgatgttct tgttcagcga ttccactgat tccttcgttg actgttccat ctccgcccat
     3481 gacaaacaca ctatgatacc cttccgtagc cgcttcgcga gtaaagtttt ttgcatcccc
     3541 tgcttttttt gtatgcaaga cgaccacttc atcaaacacc gattccaatt ttgctatcgc
     3601 taattgctca aattcctttg cttgttcacc gcctgaactg gggtttacca ctaataaaac
     3661 ttttttcatc actttctttc ccttctgatt gatttcttta atataacgat agcataaaga
     3721 aaaaaattag gctgtgatga agtactgttc atgaaacatt catttatttt ttgacaagat
     3781 aaaataccca tactatgaaa ctgaggaaaa ttaaaacaat gatataggaa ataaaagaaa
     3841 atgataggca ttgtatacct aataaagtaa aaatcttagg tggcagataa aaacacaaaa
     3901 atagcaagag aatgtaatag cgtttcttcc actttttgtt atcagacctt atagcgatca
     3961 gaggaatacc aaatgcataa ctgaaaaact cttgatgtac tgttaatatg tcacgacctt
     4021 gaataataaa tgcaacaatc cccgctataa ttagtgtgcc taataccaaa acggaaaatt
     4081 gatgaatata ttttatatac aaatgatcca ttgtacttcc tgccttttta tttgtgagaa
     4141 aaacaaatcc gtatacgtga ataacttcta gaaataaaag aaatttgcaa aaccactcca
     4201 tttatctact tctacgtgca ttttttaata tcgttttctt tatttaagat tatacagaaa
     4261 aatatctagg gtggctggat tctaagtaaa aaaaattttt aaaataaaaa gaactaaatc
     4321 aagtaataat taaactactg ttgatttagt tctaataaaa agatttagat gaacagtttt
     4381 attgatttaa atagttcata ttttttattt ataccgctta tttactactt gctgtactag
     4441 aatctgaagt gaatgtactc aaaacatttt caaagtcttt gtctttgatt tttacattag
     4501 cgtctttcaa tacttcgcca attactttat tctggaaggt actgtcactt aattttgtgt
     4561 ctgttgcaat ttctttcaat tcttttttgt atttatccat gtcgttgcct ttgttttggt
     4621 ttttcaccat tttaaccaca taatattccg tagtataagt tgaagcattg gtagaagtga
     4681 tcacatcaga aacttgacca tctttcaact taaaggctgc ttctttgact tctgccggaa
     4741 ccgttgtagt agtggaatca aatttcactt ttccgccatc ttcttttgtc gtagtatcag
     4801 ttgacttgtc tttggctaat ttagagaaat cgtctccctt atcagcagct ttcttcacat
     4861 cttttgcatc atcttcactt gctacttgga taatttgagc ttccacttct ggatggaaag
     4921 attcccaagc cgtttttaaa tcttcatcgg tcaatttgat atgtttcttt agaccttctt
     4981 gaaaggctag actttgtttg atactgtctt tgaatgtttg ttctgtgtaa cctgcagatt
     5041 tcaattgtga atcaaatgaa tcacccaatt gtttctttgt ttgatcatat tgggaatcga
     5101 tttctttggt tgatacgtca tctccatatt tatcttcaaa tacttgataa acgatcaact
     5161 gttgcacagc ggaatctgct ccttgcattt ttttcaagct atccattact tcttgttcgc
     5221 tgattgtacc gcctttataa ctaacggctg ttttttcacc ggcattcgta cagcctgaca
     5281 ataagccagt gcctagtacg atggcaagtg ctaaaaatct ttttttcatt tatcaattct
     5341 cctacttttc gttttttgcg aattgctaaa aacaaaggtg ttcaagatga aaatcatcaa
     5401 gaacaccttt actaatctgc tcgatacgtc ctgaatagat ataaggctac acaatccaga
     5461 aagttcgctc agcagaataa atgtcaagta gcacatcaca ccttaatata ctacttcttt
     5521 tgttaccgtt tttcaagtct atcttgcgtt ccgtatttaa cgtaactaat tcttagaaca
     5581 aatgttatcg attttgtttt tcttcttccg ctgttgggat attcaaatca gacactttta
     5641 tgttcgattt tccagacatt tttttgttgt ttttattaga aaaagtttgt tttttcattt
     5701 gttttctaaa gcatgatctt cttgtttcct attttggtca gatatggatc atgcgtgacc
     5761 acgataacta acgtaccttg ggaagcctgt tgcgataaga tttcaacgac ttgctcctta
     5821 tttcgtttat ctaatgatcc agttggttca tcggctaaaa tgattttgct attcttcaat
     5881 aagactctcg cacaggcgat tctttgcttc tcaccaccag ataatgtgta gataggcgta
     5941 cttagcttct tgtttatatt tacttttttc aatgcctcat actttgctgt tcgcttatct
     6001 gaaacattta aattcgaaaa cttcaatcca atatctaaat taaaatcgat tgtttcatat
     6061 tcaatcaacc caaaatcttg aaaaagaaaa gagagggcat ttctttttat caagcgcttc
     6121 tctcttccag ttaaatgttt tgtttcttga ttaaataaat aaaattgccc tgaactgaat
     6181 tgatcattca atcctaatat attcaataaa gtacttttcc ctgctccgct ctctccaact
     6241 acagtcacaa aatccccagc atccgcagtg aaacgatcca aatgaagaat cgttttgttt
     6301 cgaatgattt ttttcgcacc ttttatcact atcaacggct ccaattgtta acctccattc
     6361 atcagcaata actgactttt cttttctgta gacaaaataa aaacaactga aagaataaaa
     6421 tcaatgaagc taaagaaaaa aatattaaaa agatatttag gctctctttc tataagaaaa
     6481 aggaagatta cacttgtcgt tccccatttg atgaggttca tcatgaagaa atctttatac
     6541 gtttcaaaga gcgaataacc acttgaacga aagatagcga ttttccgaca attgtagaca
     6601 aaatatatgc ataacatgac atagctcaac aagaagaaag aaaagaaagt gagtaaaaat
     6661 atctgtatca agtaatgaaa tgatctgctt aacactttga cagctatctc ttcagtctga
     6721 gtatacggaa atgataactg caagttatca cgtaactgac tttcttcaat cagctcaaat
     6781 aacctttctt tcgacaaaga gcctatcttg atctttaacg gtggatagat ttctccgctg
     6841 agaatatttc tttcccaata cgtactgttt ttcaatgtca gtatttcaac aaccggataa
     6901 tgttcgatcc aggggataga aggaataaat gtataaatgg gttgattgtt ttttataaat
     6961 agaaatttcg gttctttttc actgatttct tgataatatt ctgttatttg cgccaggtca
     7021 ttttttaaat ctgtatgtct atatcgttca gggatcaata taacagggtg cgtttctttt
     7081 tcggttattt ggatcaacct tccagagaca tcaatcaaag gaaatttctt aagataattc
     7141 agatttattt ttatccctct gccaaactgt tcattttctt cattcaagta atctgataca
     7201 ttgactaata tacttccgtt tttattcaaa gtttcatata attcctgatc ggctgctgat
     7261 gcaaaacgat tggaataaat aaaatccacg tggtttttcc cgatggttac tggataaaat
     7321 acatgatagt cctcaccagc gatttctttt ggtgtttcat gggaaacagc taactgtgaa
     7381 gaagaaaaaa cgatagttgc taattcgaca ttggcaacgg tcaaaagaag agaaaacaac
     7441 aatccaaatg taaaaagaat gtattggata tagttgaacg cttctcttaa cgaagcgatt
     7501 ttttcaacta ataaaagaga aatcaaagag ataccctata ttccgctgaa caagaaaacg
     7561 tacatctgga acaaataaag aaattgctcc ttataataca taaaaataaa accaccaatg
     7621 attcctgcaa ttatgaatgt aataatgatt ttctttttcc ccaataaaca ccacaatact
     7681 tgatgtaatg aaaagccatt attcaacaat aaactgattt ctttattcat caataagaaa
     7741 aaggatgata acaaaaggaa taaaagaatc aatccaatag ttaaatacac tcgataatta
     7801 tatacgtctg tacttgaaat aaccgaatac gaatagctat tttcaaagtc ttcaaaaata
     7861 ttagtggcat aatcagtgtg aaatgcttga ttgaatcgtt ccacaaatag taaaatgaac
     7921 cgttcatagg cttctttttc tctcgtcatc aagaaaaatt caccttcaaa atcttttatt
     7981 ttgatcgatt cttcaatgga cgttacgcga aaggaggtat tagaataggg taccttctcg
     8041 tgagaagatt tgacatcccc ttgataatac aatgtcattt caagctttgg ctgtatcttg
     8101 aagttccaag atgtatctac ttcattggat tcatttactg tttttttcat ataagaaagc
     8161 tcagtttctg atgagacatt ttcaaatacc atgattagct gctcatattc ttcttgccca
     8221 ataaaatgtt gtggcaatcg aatcggagta taagtatctg tttgatggaa aaattcattt
     8281 gtccgataga gtacctgttt atttataata accaaggcaa aaccactcat gataccggtc
     8341 actatgattg tgagtaaaac tgtgaacttt tttttgatta tcaccactct cccttactta
     8401 aatgattctt tgataaaatc ataccgtttt tcatcaaaaa aacgtatcta tcaaatgtat
     8461 aggtcatgta gaataaatct atatactgta gaatcgaaag gagaagaaga tgaacatcgg
     8521 agaaaaaata cgaacttacc gcagaaattg taagcttacg caaaaagaat taggcgaaaa
     8581 aatcggtgtt tccgataaaa caatctctag ttgggaaaat tctcgtacaa tgccagacct
     8641 tgaaatgctg tcacttttac atcagacttt aggtctgccg attgattttc cttctattga
     8701 atcagctacc gaatcaatag aaccaacatt gccggatgaa cctcttgtta tcaagaaatc
     8761 ttattcatca aaacaaccct tctcactcaa aaagacacta tctttctttc tgctcgtctt
     8821 ttgtttggtc tatctttttc ttatcaatta tcaatataaa aatgaaacgg ttgatcgatt
     8881 caatcctttt ttgaaaccac aaatcggcta taccacactc cctgtaggat acgtggaaaa
     8941 ttccatcgaa cattgggtat gtaatgatat ctttgttcat ggtacatggc tgtcttttca
     9001 cgctggagag gtagaaaaag gtaagaatca tgctgtaatc aaacacaaag gaaaacacgt
     9061 catgaacgtt cgcctgctca cttgggaagc cattccctca gattaccaag aaatcctcat
     9121 ccaagactat gacgatgcct taaaaagaag ccctcaggag ccagataggc attaagtagg
     9181 agatgaacgt agagatagaa aaaatcaatg cacatgatct tatcaaaaaa aaacaggggt
     9241 acaaattaat tgaaaaagct ttgagatgaa agttcctaaa taaaaaagtt cagaatgata
     9301 ggtaaaaaaa tgactaacta ttctagtatt aggctatttg tattattctt ctgttatttt
     9361 tatatcaaaa aatccagaaa taactaaata taggtatttc tggcttatag tataatattt
     9421 acgccacagc ccccaatgat tctttttgga atcatgatca aggacggaca tacacaaaaa
     9481 tattttgccc attcgatccg aatagattaa cgactaatct agtaagtaat atagattggt
     9541 acgtagtcaa accagcaaat ggaaaagttg tctattccac cccaagggct ttaaagacag
     9601 catcttccgg cgtttgataa aaaatcaaat taaaggtacc cattaattct gggggtacag
     9661 ttccaatatc agcagcgctt atcataggta caagtacttt tttcgctccg gcatcttttg
     9721 ctacttgtaa acagttagct aaattatcta ccttaatcat agaaccacca attgtaatat
     9781 cccctaaaat aactaaactt ggtaatacag gtttatttaa ggaaactgag cataaagcta
     9841 ttatagttga taacgataat gtttttgtca taccaatgcc attcatatct tgaacatgaa
     9901 cgacaaaatc ttttgtcgtc aaactaatag actgactaac acttccataa ttagctctta
     9961 aatatcggta tgccgaatcc atcgcttctc ttgctccagc atctgaattg atcccagtac
    10021 gttcaaactt tccatttccc gaagtcattt gcgtttccaa tttataggta cctaattgcc
    10081 cagttttgcc ataagatacc gtgtacaaat gccctggctt ccctaaccct tctggaatca
    10141 aagttcctcc accttgttca ggaacagaaa catactcttc tcgctcttct tctaaatcaa
    10201 tgtatgaaaa attgacatca taaaattcca ttccaccaat tttctttaat tgttctttta
    10261 cacgacgacg catttcaaga gcaaatctta gtatttcttc gacatcactt ttttcaaatc
    10321 taccatcagg atacaacagt ttcatcatcc cagatacaat ccgacgaact gcaatcgtat
    10381 cccgctgatt taattgagaa ccaagtttga aatatttatc aaaactatcg ccaaaactaa
    10441 cttttcgaag ctcacgcatg acttcagaaa aataatctgt aatgaagcca tagtcatttg
    10501 taaaaaaatc tggtcgatat ttaggaattt cccaacctgg taaataacaa tgcatccgat
    10561 ccaaaaaggc tgaatccgtc cccataacct ccggaaatgg ctcaaataaa ttcgaagttt
    10621 tcaatattac atcaacgctt tgattaatat ttcctacaaa agccattgat gctgaagcat
    10681 tcttttcttc tttgcctcta gcaaaagatc ctgaagccat gtaatctttc atgatttgaa
    10741 cgccatcatt atccttaaat ttaatcccag caacttcgtc aaaagcaaca cagtcccaca
    10801 tacctacaag tcccattgta cgactagcca tattatagaa aaggtttgct actgttgttt
    10861 gtccacctga aacaaggatt gagtttggtg aaatttcttt atatacatgc gatttacctg
    10921 taccacgtgg tcctagttca cagagattaa aattattttc aattaatgga ataagtcttg
    10981 ctaaatgaag ccattttacc cttttattaa attgtgtagg ttccatacca atggaccgta
    11041 gaagtaagtc aatccattca tttgtagtaa actccttgcg agccatcttg taagcctcaa
    11101 tgtctaaacc aggcatttgg attggatcaa ccttttttgc aataaaaggg ctattccaac
    11161 gatcattctc atcataccaa tattccatcg aaacaataca ccagatcccc ccacctaata
    11221 atcgatcaaa ttttttcgga tactcttcac taatttgaac attttttaat cccaggttag
    11281 agaattctgc ttcataacaa tctttctttt catttaaatg tacagttact ttatcaataa
    11341 ctgtataacc acccaattca cgaatttttg cttttacttt ttctgcttca tcaggacgca
    11401 catagtttcg agcaagaata tttttaacat tttccacacc tttttcaacc aatgtttcat
    11461 ccaatgacga agcatacata ccaagtaaat attccaatac ataaacaggt acattcgcac
    11521 cttctttaat tttctttgtt aaatcttttc tgacaatctt tccgggaaag aattcagata
    11581 actttaaaat ttcctgttgt tccactagaa ttcctccatg tgttcagtca ttataatagc
    11641 aattaaagta tatcatactt aaccagtagg cttgataata caaaagaaaa agtatccaca
    11701 aaaaattgtg gatacctcgt ttttatatat caaaatcaaa tgattctgca aaaggattat
    11761 ctataatgaa ttttattcgc tcggtcaaat catttttttg attttttatc actaaataat
    11821 aagtatcttc aactgtatat cgacgattta caaattcaaa aacaaattta gtaaaccgct
    11881 gatttgcatc ttctgttttt gaatccgcaa catagatttc ttcatttgag atacgttcac
    11941 catattcatc ttcaaaataa agccagaaag atgcggggtc ataaacatca ctaattgcat
    12001 ttttttgata gaattctaac gtggttgata atcctgtaat tctgcggttg ctagtcatta
    12061 attcaattgc tactggttcc tttgcattgc tacctttggc taccgtaatt tctagaacag
    12121 ggactagcat ttcttgaata gatgaccctc catgaacgta gctttgtccc ccgccagctt
    12181 tcttaaaaat acttgaagta atcgggacac aaatgtttct agtgtcatca tttcctaaag
    12241 aatctcccaa agagtaattt ttcgtaccaa ttatttcgta ttcttcttca ctaagaataa
    12301 aacgacgttc tacacgatct ttttcatttc tagatggatt ttcaatctta tctacttctt
    12361 caacgtggct tcttttataa ataaatccat gatcagccgt aactataaaa cgatagatac
    12421 tgccatcatt atgcaagcga ttaataagtc gggaaatttc gcttatcgct aaatcacagg
    12481 cctcaaaaac tcgattttca ttcgagtgat cacctgttct atccacttga tcgtgataaa
    12541 tataaatgac tgatttgcca ttaaatactt ctcgtacctc agccttattc atcttaacca
    12601 catcatcata atttaaagct acagcatttg catctcgttg ctggagaatc gcatttcgat
    12661 tggataaacc attcgttttt ttcccatcaa tcagtacttc tgttccttca ttgtaagtta
    12721 gttgattgtt tggtaataag gcggctttac cgaattcagt aactgaaggt aatacagaaa
    12781 gaaagctagc catgtttgtt gaatacttct tttctctaac taacttacgt tctaaattca
    12841 tccctaactc atatcgaaaa gcatctgaaa taataactac agttttaaca gagcgtttca
    12901 ttacagcttg attataaaat tttcgaatgg atggacgatt cttaaattca aaagtttgat
    12961 tccaaatttg tcctgattga tcaagaaact tcgaataatt tgcttcaact aatcgataca
    13021 attggccata tttttgcttt tcttctatat gatcactatt ccaaataaat ttccgataat
    13081 gcgtatcaac ccaatacatt tccttctcat attgagttag caaattatcc atgttcatcg
    13141 gcaagcacaa tctgttttta tccacaagat aataagcatg tttcaataat tgatactcat
    13201 aaatataatc cgatgcgaaa tgcatttttt cgcgctgctt taaactatca aaaattgttt
    13261 gtcctgcaat tttcgttgta gtgtcagaag cctttaatcg ttctgcataa aacattaata
    13321 tttttgcatg aatctcagaa aatacgtctg cttcaattag atcatcaatt tctatactgt
    13381 ctaataatcc atcaccatca atagcctgat atactttttt agatagctgt tcaaagcttt
    13441 ccatgtaacg tgtatcattc ataaactgat ccatgaaagt aataatgttt gctttcaaat
    13501 gtagtatttc aaatcctttg aacttcttcg gcatctcttg atcaatttga taataaaaat
    13561 agttcaaata aagacacatc gtcagctttt ccaatgttgg ctggctatcc gtaaagccaa
    13621 atttcatttg aataaattcc caaaatttag ctgttaactg atacttatca agttccctta
    13681 aaggattctc cctactttct gtaaagcttt ttagaactac acgcagtaaa tcatttaatc
    13741 gaatactttt cgatttcaac aaaacagcca ttatcattaa ttcaatcgtt tctgatttat
    13801 taattgtcat atgcgtacta aattcaccaa aacttctcat gcgatccttt gcattaaaga
    13861 aattacgata ctgtttaact gtctgatgaa atctaagtgg aatagccaat tcattcatga
    13921 taatcgctaa gcggtctgca ctaaattcct ctgaataatt caatacactc aacaaatgat
    13981 tatcttcatc tttatcatcc caacgaggaa atggcgcata gattaaatag ttagtttcgg
    14041 gatcttcata ttccaataaa cgcttagttt taaattgtgc gtccttttct aatcgataga
    14101 tttttgcatt ttgaatgacc aatgagtcaa tttcttcaag aaaatcctga tttgaatcaa
    14161 accaaaaaat gattttccta catccataat taggaaaacg ttgatttaat ttttcttcaa
    14221 tttgttgcgt atttatatct gtcatcaatc tcacctaatc gttctctttc tatacccctt
    14281 atattgacat aatttggata atttcgcacg caatttaaga ataaaaaaga aagttgttag
    14341 aaaacaactt tcttagataa ctattttttt ggttctttga ccccttttgc aaaaatttgg
    14401 aatttctcgc cggttttagg atcacgctgc aacttatcat aattgacaat tacaccatca
    14461 tctaagtcta attcaattcg ttttaatgct aagtgaccca acttctcgtc atactcacga
    14521 acttctttta attgcttctg aatctttaca atttcttttg tcattgcatt tctttctttt
    14581 gggttatcac ttgttgaaat ttgttgctga cgcaattcga ttcgattgtc atacgctttt
    14641 tgtagttcgt gtaggtattc agtacgtact tttcctaatt gatctggtgt atagcgatgc
    14701 aagtacatta acgctttaaa gccattttgt tttcctgagt ccaattgcca ataaattggt
    14761 cgattggagt atgtttttaa atggtctttg taaaaatctt gtacgaagta acgacgaata
    14821 atttctcgac ttgtcccttt gccacctaaa gtgtcagcga taaactggag attttcttca
    14881 agggtttctt taccaaaagt aatctcaacg aaatcaatga aacgattgac aatgtcaatt
    14941 tggctatcct tgaaatactc atcatcggtg atgagtaaaa cattatcagt atcaggttta
    15001 aatttttgat agcgggaagg atcccattcg ccgccagcga agatgagacc atcttcgtct
    15061 agggagtaac gaccgaagat acaacctatt gaataagaaa taaaatcctt aatttccctc
    15121 gccttatcag gtaaccttgc agagatatat tcatcttgaa cctcttttgt taattctttt
    15181 tcaagagaat aatgattaat gaatatgtcg ttcagttcct cttcattcga ttttagagta
    15241 ttaaattgat taaccaactg cctacttaga cagttaaatg cctctgagag atctttttta
    15301 aacatataac ttaacaaaat gtttcttcta aactcgtatg acgtttcaag agcattatag
    15361 tcttttctag ctatatcgat attttcatcc actttttctc ttattttttt taattttctc
    15421 tcagatgtaa ctttaagaaa aggtagtttt cccattggtc cttcatggta atccaaggtg
    15481 ggagaaataa aagttaaaaa gtgattaact aatttagagt ttacatagcc aaatatttct
    15541 tcaaagtcag ttatatcctt tgagaacaga acagatcctt tagtttcaaa aattgcctga
    15601 ttctgcaatc taaaagatac ttgtccagat gaaagtgtcg accaagtaat tcccttttta
    15661 aaatagtaat taagattttg tggtctagat tttaacttcc cattttcatt aacataattt
    15721 tttatttcat ctccatcatt ctcccagtta accacgtatt cattgtttcc ataccatttt
    15781 ctaaaacgac cacctttagt tgtaggaaac catttttttc tagacttttt agcgtcctct
    15841 aatgttttag catcaaactt tattttgtta aattctactt caaaccaata ccgcaaaaat
    15901 ttattgttat ttccggttgc caacccttgt tttgcatctg caacatcgtt agttaatttt
    15961 ccttgagcaa aatcagtgat tacgttatcg cttgcccagt aagcaatcgg cattcctggg
    16021 atttttttga agttgtcttg attagtacta taaaaataat cgcattcacc atgctgatga
    16081 attgcttcta acgttttaat tttttgaact tccattccac ctttaaaatc tgataatttt
    16141 atatagcttc catcttgttc atttgaattt tttatcgtaa acgtacaaat tggaacggtt
    16201 gcttcttcaa aagctgaata ctccatttga atcaaactag aaatgtttct ttcattaatt
    16261 aaaaatgagc gtaacttttc atagctagaa atgaacatcc aaacaaatgg cgtcataaag
    16321 gaagcatatc cattatcaat cagcatttgg ctattcaatt taataaacac agaaaataga
    16381 tcttttttga catcagaata gttatcattt acatattttt ttaatttctt atccatttta
    16441 ttaagataag gcggattagt gactaccgct acatatttat caactagcat ttcagccacg
    16501 tcaagaatgt gcaagtattt ttcttgtatt tccttcatcc cataaagaat atccatattc
    16561 gtaaattcgt tgaattttga tatatactct cttacttttc ctaagtattc tttagttatt
    16621 gcctgattat ttttatcgac taacttaatg attgatccaa gttctttccc attttcaaat
    16681 tgatcaaaaa ttaactcttt gtattcattc cagcgttcac tatacttatc attgttcaat
    16741 tcactaatac gctcttgata ctcgtctgtc actttaggag aatcaataaa ctctcttaaa
    16801 ttcggcgata gacttttttt caaaaaaaga cgatcgtatt gacgcccttt catcataatt
    16861 gcaaaataag acaattgata cgctctttta tcgatttcaa gaccatataa attgtattca
    16921 acgattgcac gtgcagcatc acgctcagaa tatcctaacg taagataaat ttccatcaat
    16981 acatcgaagg cgtaaactaa aatatgccca gaccccattg cgttatcgat aatttttagt
    17041 tcttctggtt ttaaattact tacagatgtt gcttgttcaa aagcatattt atctggaatt
    17101 aagtatttca acttatttct taattcacta ttgggataat gatctaacca atactttcct
    17161 aaactattgt caaccatata acgaacgacc caatctgtgg taaatagttg agttgctgcc
    17221 ggaatatctt gttttttgac aatcccttta taaatattca ccacttgatt atgtggctca
    17281 ctattatagt actgatacaa ccacccaata atctctacct gtccaccagc ttgaacatag
    17341 aaatcatcct ctggaatact taaaagatca gcgattacac catctttttt aatataagaa
    17401 gctgtaaaca aaagttctgt ataatcttct acttcttcaa atagctcagg taagtaatca
    17461 ttcaattgat tacagatttt tataaaaatc aattgataca gcttgtccat tgcttctgct
    17521 gaattatctg ttttccaagt tctgacttgt tgctgttcat tactagataa ttcttcaaag
    17581 atatcggcat cataaatatc tgtaataata tctggctcaa ttttcccact tatttcacta
    17641 gataatacac gatacgtgtc aggtaaataa tcatttacct ccataaaccg aatggcaatc
    17701 aatcggttaa accacgtata agcaacctct tcgattaact cttgaaaagc ttctgaataa
    17761 gaagtgacag aagcacgttg ttttagttct gcaatcaatt tgtttctttg cgctatttct
    17821 tttccttgaa ttcttattcc tgatttttcg atttcttgta aattgctatc aattttcttc
    17881 acatcttcaa tttttgattc atcaattcct aaacgttttg ctttagtcat tacttcatca
    17941 attaattttc tacgggcatt gaccgcgaaa ttctttatcg ctttcttatc catttttctt
    18001 tcccttctat atgtaacctt tgaaaagaca ggcacctttt tatgcctgtc ttttcactag
    18061 aattgaatcg tgatttctgt attttcttga agttgttcct tcagtttttg attaatttca
    18121 gctgttaact catcaatatc tgctgctgac ttaatagttt taacatgaac gttaagtgtt
    18181 ctcattggta ctgttttctg ttgaatagta ggttttacta tcgctatttc ttcagctttt
    18241 gctgcagagt ctatttcatc tttttcagtt tcacgaatca agtttgctgc ttcaatttgt
    18301 ttacgtgctt gttcttcttg acgtctgcgg ttttcttcat tatcgaaacg ttgattaaag
    18361 atcaaatact gttctgctac gtttaatgat aagaaaacaa gatcatctat agtattcgct
    18421 tgttcaattt ttgctttcag ttcttgaaat tcttggtcaa ctattggtac aaattgatcc
    18481 ttaaaatctt ttccttctaa taatttaaat gttgcttgtt tttcttccgt taatttattt
    18541 aatatttcct gactttccaa ctctaacagt tgattatatt gttcaataaa ttcttgaatc
    18601 aactcattta gtttcatcat atctgaataa ggatcagcct ttttcaaaat ggttttcatc
    18661 tcatgaatca attgatcaat ttcttggcta gaagtttgac gccgactttt ttcgattaat
    18721 ctaattttat cttgtgcatt ctcccagatt tttttctgag tactattttg cttgtggaaa
    18781 tttttaattt tatcatatgt ttcagcccag tcgaataatt catcgcgata ttttttgatt
    18841 gtataaaaaa agtcttcaac atctgacgtt tgaacaatta cttcaagata tttttttatt
    18901 tgctcatatt cataagcact agggtaggta taagtgtttt gtaaatcaaa ataagagcgt
    18961 aaattgtcta attgaccttt taaatatttc ttgaaatttt ccattgtatg ttcattgtta
    19021 ttttcatcaa caatattacg actttgaaac agttctctac cgatttcgtc aaccaatttt
    19081 tttgcttttg gcgaaatcac cgcgcttggt tcaattttta tcttttcact ttctcgtcgt
    19141 ttttgaataa tcattacaat actatttgga tcatccatcc gtgaaatttg tacattgtta
    19201 taaagtaaat caattttacc agacatgaaa agtttagcga tgcaccattc cacatcaagt
    19261 tctgtgaatc catacggttg ttttgtttca aaacgatcac gaattgtttt catcgtaatc
    19321 gttaggtgat ttctcttttg atcattgata aaattgaaaa tttcctgaac tgcttgctca
    19381 tttgatggat cttcaataat ttcatttttg ctttctttca ctaaatataa gatatcttct
    19441 ttttctttag gcgcatcaat ttggtttaat ttatggtata cttcttcagc cattttctga
    19501 agtgctgatt ggaattttgc tttaaagtcg gagcctgtca gttgaatttc tgcaccgtta
    19561 tagaaaaatt ttgcagattt caacagttca tttaattgat cgttgatact tgcacttagt
    19621 tcctgtaatt caccagattt ttccgaacga atcgcgtcaa agttctttac tacactcgaa
    19681 taagtcgttg ttaaataaag attcattcta gcatacattg ctatatcatc tttaaattct
    19741 ttatctgatg gcaattctac gaataataag ttacgggaac tcttaagcgc aagttctgcc
    19801 tcttgacctg ctaaatcaga gtatggtgaa ataaaattaa ctgtcatttc agcatttcca
    19861 gcttgcttgt atggacgttg atctaacact tgtgcataag taaacgtata ccggttttta
    19921 aatttatttc cacctgacat gcctaatttt tcataggcaa aactatttcg gtctagaacg
    19981 ccgtcaaaaa ttcgtttaga tagttctacg atcaaatcac tatctgtaat attttgattt
    20041 ttaatctcac gagtaatttc ctgttcttca tcagtttgga aaatataact atctaagttc
    20101 ttccgcacaa agttttcctt aattaaaagg tccaatgctt cttctactcg ttttttagtt
    20161 tccaggcggt cttcgttgat atttcttatc atcaagctcg taatattttc aacatttggt
    20221 ttgatggctt gatcaacata tttaatcatg aataaaattc gtaagacatt tacgttaaag
    20281 ttatctatat cagttggtct ttgaatatga gaattatttg tagcttgtgt aatcactcgg
    20341 ctaattgctg tatcaatcca acgttctaac gagtaataaa actgatctaa agaaaccaaa
    20401 ctggttgtat cattttcctt atttcgttca gcggcttctt taaacattgc tagtaatgaa
    20461 cgttcaccag acgataagtt tgatccttga tagctgtgat tacgaatctc ggttagaatt
    20521 tgccccaata aattgaattg atagggaata aatggataaa cttctgcgta attttcagca
    20581 tcttggaaga gctttaattc aggactatca acaaagagta atttattttt caattctgtt
    20641 tgaacagttt caaattgtaa ggctaaagaa tcattggcaa actctttttt cttcaaaata
    20701 cgttctttaa ttacttcatc ggcatttgct gaagataaac tcacagttgt ggcaaaacga
    20761 tccttgatct tagaaaaatc attatcagaa ttgttatcaa agtttgttac gtgatcaatc
    20821 gcttcctgac ttgtcactaa tacccaagcc ttaccttcac aaattcgacc caaatcttcc
    20881 acaacggttt gtaactgcaa agtcaactca cgattaccgc cgatatattg tccgacctca
    20941 tcgactagaa aggcaatatg atggtctgct tctttggaat caagatagct tttaactaga
    21001 tttgcaaagt catcaatgct tattaaataa tttcctgatg ctttttctaa aaaattatca
    21061 atagcggctt cactcataaa atcgatttta agtgccgctt ctttgatatc atcttggatc
    21121 caatcaaact catggcgctc ttcttgccat tttgccccat taatctcttc aaaagcagct
    21181 ttgaatgcat caaacttttc ttctttaatt aaccgacgtt caaaatctgc tagatgtgga
    21241 atcgtgctta atccttgcat ttcgttaaat acctttaaaa aaacattcac gattccgttt
    21301 ttgtcttttt taccacctgc atcacttttt gaatcaatat taaacagaat aacatctgta
    21361 tttatttgtg agcaccgttc catcgttgcc aaagtcagtg gatctttgat tttcccatct
    21421 tctttgaagt aatcaatggc tttcttgtca tttatttctc gatttgcgag caagtaagaa
    21481 ataattttta agaaatgaga tttacctgaa ccaaagaacc cctgaatcca aacacccatt
    21541 ttatctgttg gtgtattgat actccgttgg taggcatcaa aaattgtttt aaagtgtttt
    21601 tgtagttctt tcgtaaccac gtattcttct aattcttgtt gaacattttc atcctttgct
    21661 tgaccgacct taataactcc ttgaatattt cggtcaattg gttttgcaaa aatatcttta
    21721 attagcattt aatctcctac cttccatccc aactaaattc taaatgctcg ataataatta
    21781 tcatctttat tggtattaag aattgtcaaa cttaattcat catattcccc tggatacatc
    21841 atcacaactg gtacgcgatc aaatacctga tgcattttat ttaaaataga gtgcgctcta
    21901 attaatggat ataattcgcc aattcctgtc aggaacacaa ctgatttttc tggtgtatgg
    21961 gcatccacat attcaaaaaa tacattttct tcctcaggta aatccatttt caataaacga
    22021 ccaatgcttt ccactaattt ttgtaaacca cgtcgttctt ccatcttaat cgctttttca
    22081 gtgaaaccgc gtttttctag atactctaac ataatcacat agagattata aactttcact
    22141 tcataattat caccaacaga tgttccagat atatcattaa tataatctct tacaattaac
    22201 tcgtctttcg gatcgtagtc aaagatataa tagcctactt cattacctaa accacgattc
    22261 aataaaaaat cttctttttg aattacttca ttcaactttt ccaaatgctc ttgaatcgat
    22321 aatgacatta taaaattcct cccagtgcta gtacaatatc tttacgattc ttgtcaacta
    22381 accattgaat caatcgttta tctaataata tcggagtcat tcgtccatat tctttttccc
    22441 ctctgactaa tcctgtttca attagattcg tttgataagc ggcaataagc cgtttaatcg
    22501 tataatcttt ccattttgaa atatcttctg aacttctccg cttctctgta aaaaaagaac
    22561 ggtaatcaac tggtgttaat tgcaaatttc ctttacgtag attttcagca tatacctcag
    22621 tcataaattc attaaaaaga tcatcaatca taaggatgga aatcaaattc actaactttt
    22681 gattatctat atttaactga ttgaaaagtt gcaatccagc ttcatccagt tgactaactc
    22741 tccttttcac gttctgatag atttcttttt gacggttact gctcactgca aaaaaaatat
    22801 tttcatgttc atttttctct ttaatttcta tatctgtata tccttctagt cgtaattgaa
    22861 tatataactt gaactctgaa aaccaaaagc gtttagaaac tagaccagca gaatattttt
    22921 tattcaatag attgcctcct aatcatctat aattcaataa gtaaacaagt gttttttgct
    22981 catcgttagc attcattttt tagtatctac tatacaatac atatttatta ta
//
LOCUS       DADLIO010000044        22952 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.044, whole genome shotgun sequence.
ACCESSION   DADLIO010000044 DADLIO010000000
VERSION     DADLIO010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22952
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.044"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            <1..288
                     /locus_tag="JOX41_001810"
     CDS             <1..288
                     /locus_tag="JOX41_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449553.1"
                     /translation="LKSFLKVISKKRNLIKTTQLLKKYPGLLHTSIQFPQLITMIHRF
                     IRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVAMEKAN"
     gene            347..787
                     /locus_tag="JOX41_001811"
     CDS             347..787
                     /locus_tag="JOX41_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449554.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            799..1467
                     /locus_tag="JOX41_001812"
     CDS             799..1467
                     /locus_tag="JOX41_001812"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HAY6449555.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            1531..2154
                     /locus_tag="JOX41_001813"
     CDS             1531..2154
                     /locus_tag="JOX41_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HAY6449556.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            2210..2596
                     /locus_tag="JOX41_001814"
     CDS             2210..2596
                     /locus_tag="JOX41_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HAY6449557.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            2809..4200
                     /locus_tag="JOX41_001815"
     CDS             2809..4200
                     /locus_tag="JOX41_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HAY6449558.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            4547..5194
                     /locus_tag="JOX41_001816"
     CDS             4547..5194
                     /locus_tag="JOX41_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HAY6449559.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     gene            5587..8232
                     /locus_tag="JOX41_001817"
     CDS             5587..8232
                     /locus_tag="JOX41_001817"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HAY6449560.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            8542..9855
                     /locus_tag="JOX41_001818"
     CDS             8542..9855
                     /locus_tag="JOX41_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HAY6449561.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            9845..10498
                     /locus_tag="JOX41_001819"
     CDS             9845..10498
                     /locus_tag="JOX41_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAY6449562.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            10553..11245
                     /locus_tag="JOX41_001820"
     CDS             10553..11245
                     /locus_tag="JOX41_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HAY6449563.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            11395..11595
                     /locus_tag="JOX41_001821"
     CDS             11395..11595
                     /locus_tag="JOX41_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAY6449564.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(11849..13528)
                     /locus_tag="JOX41_001822"
     CDS             complement(11849..13528)
                     /locus_tag="JOX41_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HAY6449565.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(13530..13742)
                     /locus_tag="JOX41_001823"
     CDS             complement(13530..13742)
                     /locus_tag="JOX41_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HAY6449566.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            14135..15865
                     /gene="efrA"
                     /locus_tag="JOX41_001824"
     CDS             14135..15865
                     /gene="efrA"
                     /locus_tag="JOX41_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HAY6449567.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            15862..17622
                     /gene="efrB"
                     /locus_tag="JOX41_001825"
     CDS             15862..17622
                     /gene="efrB"
                     /locus_tag="JOX41_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HAY6449568.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            17717..17914
                     /locus_tag="JOX41_001826"
     CDS             17717..17914
                     /locus_tag="JOX41_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449569.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            18067..18552
                     /locus_tag="JOX41_001827"
     CDS             18067..18552
                     /locus_tag="JOX41_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HAY6449570.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(18656..19249)
                     /gene="clpP"
                     /locus_tag="JOX41_001828"
     CDS             complement(18656..19249)
                     /gene="clpP"
                     /locus_tag="JOX41_001828"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HAY6449571.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            19429..19956
                     /locus_tag="JOX41_001829"
     CDS             19429..19956
                     /locus_tag="JOX41_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HAY6449572.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            20047..20784
                     /locus_tag="JOX41_001830"
     CDS             20047..20784
                     /locus_tag="JOX41_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAY6449573.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            20788..21705
                     /gene="miaA"
                     /locus_tag="JOX41_001831"
     CDS             20788..21705
                     /gene="miaA"
                     /locus_tag="JOX41_001831"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HAY6449574.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAVDFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            21707..22936
                     /gene="hflX"
                     /locus_tag="JOX41_001832"
     CDS             21707..22936
                     /gene="hflX"
                     /locus_tag="JOX41_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HAY6449575.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT         7463 a         3945 c         4966 g         6578 t
ORIGIN      
        1 ctaaaaagct ttttaaaagt gatcagtaaa aaacggaatc tgatcaaaac gacacagctg
       61 ttgaaaaaat atccaggtct gcttcacacg tctattcaat ttcctcaatt gattacgatg
      121 atccatcgtt ttatacgtat gcaacagcta ccatctaaga agctgtttct tccattgacg
      181 gacacatttc gagtagtcaa cagagaagat aaaaagaaag tgattgtgat tgactttacc
      241 agaaatcgga atgtccttca ccaagttgca atggaaaagg ccaattaagg ctttttcttt
      301 ttggattttt ttgtcataat aaatattaga tgatggagga gataatatga tgcaaacatg
      361 gttagaaagg ctaatacgat ttcagcagaa ctatcacaaa cttatgcagg gaagatatgc
      421 gaaatttgat cagttgaatc gcggtctatt gatcgctgcg cttgtcttta gtttgctaag
      481 tcgttggttg ccctatagaa tcggacaatt gttgttcatc gtctttttcg gatggatgat
      541 atttcgtttc ctatcaaaaa aaatctaccc cagactaaat gagaatcaac gttatttgaa
      601 atatcttgat agagtcaaag aaaaatatca tcagataaaa aacaaaaagc aagtcaaaat
      661 ggatcgaaaa agttatactt tttttgagtg cccgaattgt catcaaaagc agcgtgcacc
      721 taaaggaaaa ggacgaatac gtgtgacatg caaaacatgt ggtataaaat tcgaaacgaa
      781 tgtttaaggg agaaaagaat gaaattagta ttattacgtc atggcgaaag cgaagcaaat
      841 tttgaaaatt actggacagg atggctagat gtcgccttaa cagaaaaagg aaaagaacaa
      901 gcagcagttg ccggtcaaaa aatgcttgaa gccggacttc aattcgatgc cgtttatacc
      961 tctgttttga aacgtgcgat tcttaccgga caagtcgcac tagaagaaat gggtcagtta
     1021 tggcttccta taataaaaac atggcgtcta aatgaacggc attatgggga tcttgtgggt
     1081 aaaaacaaag ataagatgaa agaaatatac ggaaaagatc aagtaaaaac atggcgcaga
     1141 ggatatacgg aagttccgcc gttaaccgca gaaaatagat ttgaccgcag atatgatcac
     1201 ttggatccgc atttgatccc atacggagaa agtctggaaa tgacagtgaa tcggatcatt
     1261 cccttatggc aagatcatct agcaccaaaa ctaaaagatc ggcaagattt actagttgtg
     1321 ggtcatggta atagcatccg agcactgaca aaatatttag aagatgttcc tgaagatcaa
     1381 atggatacga tcgatatccc aaatgcacaa ccaatccagt atacattagc agatgatttg
     1441 acaattctgg acaaaaaaat actttaaaga acacctttat ctaaaagtga gagatagaaa
     1501 aaagaagcaa aggaatggaa caaaaggaac atgaaaaatt atatatggga ctttgatggt
     1561 acattgtttg atacgtatcc cgcaatggta gatggtgcat ggcaagcact aaaagatttt
     1621 ggtatcagta tggacaaaaa agaaatctac ttcaaaatga aaaagtattc tactagttat
     1681 ttgatcaatg aatcaaactt gaatgccaga gagtttaatg aattatttca ccgatatgaa
     1741 aaagaaagta cggaagtttc ccgtccattt ccagaaacga aacaagtact ggaaatgcta
     1801 aaagacaacg gcggtcgtca tttcatcctg acccaccgtt tgacagaatc aacatggggc
     1861 ctgttaaaag aacatcgatt ggcacatctg attgaggaag tagtagggat cgatcaggac
     1921 tttcctcgta aacctgatcc agcatcttta aattatttga tcgatacttt tcatttagaa
     1981 agaacagaca cgatgatgat cggcgatcgt cgtttagata tcgaagcagg gaaaaatgca
     2041 ggagtcgcta cttgtcttta cgacatcgat cattttctgg gtgagatccc ggcagattat
     2101 gtggtaggaa atctgaatga aatccttacc ttgcagagca tcattaaaaa gtagtatccc
     2161 ctttcaaagg agatatgtta taattttcat aaaggagtga taaaattata tggaaatcag
     2221 aagacaaaaa gaagttgtag aagcatttca ttatgatatg agattgccga accaagaagt
     2281 agaaacagat ttgaaagtag gcttctcgcc tttaaaagaa acgatcgaaa actatccgaa
     2341 agaacatagc atcgtaggag cacgcttaga gttccgttta gtgtttgata catatgtttt
     2401 atctggaagt gtgagtcaga tcaatcatat cctcaatcgg aaaattgaag gtcaaaatga
     2461 tgtcacacaa gaagaagtgg acgagctagt agcaccgtta ttcgatatcg tacgccgaat
     2521 gtcttatgag gtgacagaga tcgccttaga tcagcctggg gtaaaattga attttcaatc
     2581 agaaaaacaa gaatagacag taaaaacata cctgcgatag attaaagcta tcacaggtat
     2641 gtttttttat tactaattgt aagcaaaaag aatgtcattt cgataaaaat cgtctaaaat
     2701 ataaaagtca ctgaaaaaaa ttttttcagg aggatggttg aagaatcatt ctcgggaacc
     2761 tttacttcct tcgatggact tgtcattaat aatatgagga ggagaaaaat gacaacactc
     2821 atcacagttt tagtggttct agtttttgcg gcattattat atgtgttcta tcgtatgcaa
     2881 aagcgccata caaaattttc aacacgcgtc tttacagcat taggagttgg tatcgtcttt
     2941 ggcggtctgc ttcaattgat ctttggtgta gacgacaaag tcgttactca atcaatggaa
     3001 tggatcggga ttgtaggtca aggatatgta tcattcttgc aaatgctagt tatgccttta
     3061 gtgtttattt cgatcattgg tgcattcaca aaaatgaaag tttctgaaaa gctagggaaa
     3121 attagtgcga ctgtattgac ttctttactt ggaacaacag ctattgcagc attgatcgga
     3181 attggttcaa caatgctgtt cggactccaa ggagctaaat tcacacaagg agctgcagaa
     3241 acagcacgaa tctctgaact ggcaacacgt caggaaacag ttgaaaactt atcgattcca
     3301 cagcagattt tatcctttat ccctaaaaac gtttttgctg atttagcagg tagtcgtgca
     3361 acaagtacga ttggagtcgt tattttcgcg gcatttgtcg gaatcgctta tctaggcgtg
     3421 aaaagaaaag cgccaaaaga agcagcattc ttttcagatt tagtcgacag tctgtataaa
     3481 atcattatgc ggatcgtgac gcttgttttg cgtttgacac cttatggagt atttgctttg
     3541 atgacaaacg ttttggcaac aagtgatttt gcagctatcg tcaatttagg taaatttgtc
     3601 gttgcttctt acgtagcatt gcttgctgtt ttgattgtcc actcactgat tttgattggt
     3661 gcaaaagtca atccaatcaa ctatttcaaa aaagcctttc cggtattgag ctttgcgttt
     3721 acttcacgtt caagtgctgg agctttgcca ttgaatatcg agactcagac aaaagcttta
     3781 ggagtagatg atgcaacagc taatttctca gcaagttttg gtttgtctat tggacaaaac
     3841 ggctgtgctg gcgtttatcc agctatgttg gcaacgatcg tcgcaccagc agctggagtg
     3901 aatgtcttta gtttggaatt tattttgatg cttgtggcaa ttgtaacaat cagttctttt
     3961 ggtgtagctg gagtcggtgg gggcgcaaca tttgcttcac tgatcgtttt aggggcaatg
     4021 aacttgccag tagcaatcgt tgggttagtt atctctgttg aaccattaat cgatatggca
     4081 cgtacagcag taaacgtcag cggtagcatg gtagctggta tcgtgacaag tgcacgcatc
     4141 aaagatttag atcgcgatgt catcaatgat gattctaaag tgatcgatgt gaatgcatag
     4201 tcaaaaagag gttgtgatag aagtggtcag ctttaagaaa taagaagaag tttcctaaaa
     4261 atagtttctc aaatttttgt gaaatttcgg cttatttccg agaagctact tctgaaacac
     4321 cgtgaataag aggttgtgaa aaagctgccc tgcatcaagt aataagaaca gccaaacaaa
     4381 aatagttcct catattttac gtttggttga gcttattacc gcagatgcaa gcttttgaac
     4441 accgttttat ttgtctcaca cccttttcct tcctacttgt aaccttgctc ccgtgttaga
     4501 aacatgttac actaaatatg tgaaattatt aacaaggagc gtcgttatgc gagaaaaaac
     4561 agatacactg ccaaaagcaa ctgcgaaaag attaccttta tatttacgct acttgaagat
     4621 gctggatgac tcaggtataa gtagaatcaa atcaaatgag ttcagcgaaa tcacccaaat
     4681 tccttctgca acgatccgca gagacttctc gcaattaggc gagctaggca gaagcggata
     4741 tggctatgat gtcccttttc ttatcgatgt attcaataat atccttaata ctaaagaaga
     4801 aaaacgaatc gcattagtag gatatggaaa tcttggcaaa gcattgaaac acaacaattt
     4861 tagaagaaat gaaaatctaa atatcgtgtg cgtctttgat aatgatccag cactgatcaa
     4921 tcgagtaatt gatggagaaa tgatctatcc gattgatcgt ttcgcggaga tagccaaagc
     4981 aaaaaatgtg acagtagcaa tctctacggt accaagtaaa tattcacaat ctgctattga
     5041 tgaaattgtc aaaggaaatg taaccgctat acttaatttt gcgcctgaca gagtaactgt
     5101 cccagcttat gtcaatgttc aatacattga tttgacaacc gagttgcaga cgcttattta
     5161 ctttgatgag aattactcag aagttttttc ttaggaaaat ttgagtaggc ttattgatct
     5221 tgcgagaact cgtcgtaatt ctttcaaaaa ttttttagta ctaaatgaag tggttttttc
     5281 acgaccactt gttgactaaa aaaaaaaacc attgtagaat gaagcataac gctgaacaag
     5341 aggagtaact ggcacattca ttcttagaga gagaactatc tgctgaaagg ttctcaatga
     5401 caaccagtga aggtagcttg ggagtttctg tcttgaatgg agtagagata gacgagtcgt
     5461 gatcgttaac tcacttgaga ggcaataatg attgattatt gcaatttagg tggtaccgcg
     5521 taaatcatac gtcctagaat acgaaagtat tttaggacgt tttttagttt aaaggaggaa
     5581 aacagcatga cggaagaaaa taacctatca acaaaatata atccgcaaga agttgaagct
     5641 ggacgttatc agcattggtt agaacaagat ttgtttaaac cgagcggaga taaaaaagca
     5701 aaaccttatt caatcgtaat cccgccccca aatgttactg gaaaacttca tttagggcat
     5761 gcttgggata cgaccttgca agatatgctg attcgtcaaa agagaatgca aggatatgat
     5821 actttatggc tgcctggtat ggaccatgca ggaatcgcga cacaagcaaa agtagaagcg
     5881 aagcttagag agcaagggat ttctcgttat gatctaggtc gtgaaaagtt catcgatcaa
     5941 gtgtgggaat ggaaagaaga gtatgcgagc cacatccgcg aacagtgggc taaaatgggc
     6001 ttatctttag attacagtag ggaacgtttt acattagatg atggattatc tgaagcagta
     6061 cgtaaagttt ttgttacctt atacgaaaaa ggtttgattt atcgtggtga atatatcatc
     6121 aactgggatc ctcaagcacg aacagctcta tctgatatcg aagttattca taaagatatc
     6181 gaaggcgcct tttatcatat gagctatgaa ctagcagatg gatcaggcgt agtagaaatt
     6241 gcgacaaccc gtccagaaac gatgttggga gatacggcga ttgctgttca tccagaagac
     6301 gagcgttatc aagcgctcat cggcaaaaaa gtgattctac ctttagtcaa taaacaaatc
     6361 ccaatcattg cagatgaata tgtagatatg gaattcggga caggtgtagt aaaaatcact
     6421 ccagcacatg atccaaacga ctttgaggta ggtaatcgtc atgatcttcc acgcgtaaat
     6481 gttatggatg atgatggtac gatgaatgaa ctagcaggaa aatatgctgg aatggaacgt
     6541 tttgctgctc gtaaagcaat cgtgcaagat ctgaaagaaa tcggtcgatt gattaaaatc
     6601 gatacgatga tccacagtgt gggtcattcc gagcggacag gtgtcgttgt tgaacctcgg
     6661 ctgtctactc aatggtttgt aaaaatggcg ccgttagcga aaaaagccat tgataaccaa
     6721 gaaacagatc aagcagtgga attcttccct ccaagattca atcaaacgtt tttacgttgg
     6781 atggaaaatg tccatgattg ggtaatctca cgacaattat ggtggggaca tcaaattcct
     6841 gcatggtatc acaaagaaac aggtgaaatg tatgtaggga tggaagcacc agcggatagt
     6901 gaaaactggg tacaagatcc tgatgtttta gacacttggt ttagttcagc tttgtggcct
     6961 ttctcaacaa tgggctggcc agatacggaa agcgaagatt ataagcgata cttccctact
     7021 agcactttag taaccggtta tgacatcatt ttcttctggg taagcagaat gattttccaa
     7081 agcttggaat ttactggcga acgtccattt gagaatgtct tgattcatgg attgattcgt
     7141 gacgaacaag ggcggaagat gagtaaatca ttaggtaatg gaatcgatcc gatggaagta
     7201 atcgaaaagt atggagcaga tgctctccgc tggttcttat cgaatggttc tgcaccagga
     7261 caagatgtcc gcttcagcta tgaaaaaatg gatgcttctt ggaactttat caacaaaatc
     7321 tggaatgctt cacgtttcgt tatcatgaat atcgaaggaa tgaccgtaga agagatcgat
     7381 ttatctggag aaaaatcagt ggctgaccgg tggatcctta ctcgtttgaa tgaaacgatc
     7441 gaacgagtaa ctgagctatt tgatcgtttt gaatttggtg aagcaggtcg acaactgtat
     7501 aactttatct gggatgattt ttgtgactgg tacatcgaaa tgagtaaaga agtactttat
     7561 ggagatgatg ctgtttcaaa acaaaccacc cgtagcatct tagtccatac acttgatcag
     7621 atcctacgtt tattgcatcc aatcatgcca ttcgttacag aagaaatatg ggaacatatt
     7681 cctcatcagg gaaattctct agtagtggca gaatatcctg ttgtacgtcc agagtttgat
     7741 gatgaaacag cttctaaagg gatggaagta ttgaaagaat tgattcgagc cgttcgaaat
     7801 attcgttcag aagtgaatac accattgtct aaaccaatta cgttgctaat taaaacaaac
     7861 gatgctaaaa tcgatcaatt tttagttgaa aatacaagct atatcgaacg cttctgtaat
     7921 cccgaagagt tgacgatatc aagtgagatc actgcgccag atctagcgat gtcagctgtt
     7981 ctgacaggtg cagaaatctt cttgccgtta gcaggattga tcaatattga agaagaaatc
     8041 aaacgattag aaaaagaact ggaaaagtgg acaagcgaag taaaacgtgt ccaaggaaaa
     8101 ctttctaatg aacgttttgt ttctaacgcg ccggaagaag tagtagaggc agagcgtgca
     8161 aaagaaaaag attatttaga gaagcaaacg gctgtcaaag aacgaatcga aagtttgcgt
     8221 actattcaat aagaatagaa aaagagagtg tgaaatcagc tagctattac taaaagctag
     8281 ctgattgaac atcgttacag gaaagagttt gagcctcact cttagcttcg attcataagg
     8341 agatgtgaca taaattttgt cgcatctctt ttttagtcta ctcttattat gtaggagaag
     8401 gagggaggtg gatcatgtat caagagtcaa taaagtagtt gataaaatcg ttcctctctc
     8461 tgtttctttt ctctttgtca tacttttatt tttcttatgt gttctatttg ttataataaa
     8521 agagaaatgg gggaattgtt gatgacgatt gaagaagcaa tagaatggat ccatagtcga
     8581 ttaccatttg gttcacgtcc tggccttgac cgagtcgaag ctttattaga agtggtaggg
     8641 catccagaga gaaaagtaaa aacgatccat atcgctggaa caaacggaaa aggttctact
     8701 gtagcttatt tgagaagcct attagaagag gctgggctga cagtaggtac atttacttca
     8761 ccttatatcg aaacgttcaa tgaacggatc gcaatcaatg gcaaaagcat tccagacaat
     8821 gatttgatcc agcttgtaaa aaaatatcag ccactgatca aacaacttga tcaatttgaa
     8881 gcagtagctg gtattactga attcgagaca ttaacagcaa tggcatttga ttattttttg
     8941 atgaagaaag tggacgtagc gattatcgaa gttggcttag gcggcttatt ggattctacc
     9001 aatgtagctg taccaatgct gacgggaata acaacgattg gacttgatca taccgaaata
     9061 cttggagata caattgaaga aatcgctgca caaaaagctg gaatcatcaa acaaggcgtt
     9121 ccagtagtaa caggaaatat tgccccagaa gcttttactg tcatccaaca aacagctaaa
     9181 gcaaaaaatg caccgcttta tgtatacggg gaaaattata aaataaacta tctgcatcct
     9241 gatgagatgt ggggagaagt atttgaattt tttaatgaaa taggaaagat ccctcaatta
     9301 accactccgc ttttagggca acatcaagct gaaaatgcag gagtagccat cgaattgtat
     9361 tttgtttact gtcaattgga aaagctgcct ttccgagaaa aagatgtttt gaagggattg
     9421 aagaaatctc gatggccagg aagaatggag cgtttgagta acgagccatt agttgtttta
     9481 gatggtgccc ataatacgca tgcaatgaac cggcttgttg agaatttgaa aaaagaattc
     9541 aaaggatatc aaatcaacat tttgttttcc gccttacgaa ctaaaaatgt tagagaaatg
     9601 ctagaacgat tgcagcaagt accaaatgtc catatttatt tgacgacctt tgaacatcca
     9661 aaagccatcg aattaagtga agtatcagat ttagcaagtg agagagtatc aatcgtttca
     9721 ttgtggcaat tcggattagc agatatattg gaaaagatga caaatgaaga cgtattagtt
     9781 gtgaccggtt cactttattt catttcagaa gttcgccatt tattaataca attaggagga
     9841 gatcatgaag tataatgcag tgatttttga catggatggt ttgctgttcg acacagagtt
     9901 agtgtattac gaagccacac aagtagtagc agacaagatg ggttttcctt atgataaaga
     9961 cctgtattta aaattcttag gtgtttcaga tgaagaagta tgggcgaatt atcatatgat
    10021 tttctcggaa tttggcaaaa caagtgtaca aagattcata gatgattcat accaggaaac
    10081 gcttgaacgt ttttcgcaag gagcggtaca aatgaagccc ggtgtgttgg aactcctctc
    10141 ttttttagaa gaacatcaga ttcccaaagt tgtcgcttcc agtaaccaac gagcagtcat
    10201 tgaactttta ttgaagaaga acaatctgtt tgaacgattt gagacgattg tttctgcaga
    10261 aaatgttcaa cgagcaaaac cagacccaga aattttcttg ttagctaatc agaagctagg
    10321 tacagcgaag aaagaaacat tgattttaga agattcacaa aatggtattt tagcagcttc
    10381 tgcggctgag atcccggtag tcatggtacc agatctgctt ccaccatccc aagaattgat
    10441 caaaaaaaca gctggggttg tttcttcttt acatgaaatc cctgcattgt taaaataaaa
    10501 atccatctct tttcgtatct tattttagat aagatagaaa ggagatgttt ttttgggaaa
    10561 acgattgatc aaagaagtac ctactagctc tttaccaagg gaacgtatgg aaatttatgg
    10621 cgcggaagct ttatcggatc aggagctttt ggcaatctta ctgcgtaccg gtcaacaccc
    10681 ttatagtgtg atgtcgattg ctggaaatct gttaaaaacg tttggaggac tggcctcttt
    10741 acgacaggct actttgcatg agttagaaga gattcgaggg ataggacgcg tgaaagcaat
    10801 cgaaatcaaa gccttgatcg aattaggtcg acgaattcag acggatcatg aaagagcggc
    10861 tccaccggtt cgtaccagct acgaattggc ccagcaattg attctggaaa tgaaagatca
    10921 caaacaagaa catttggttt gtatttattt ggacacgaag aatcaagtga tcttaaaaaa
    10981 aacagtgttc atcggttcgc tgaatcagtc agtcgctcat cctagagaaa ttttccatta
    11041 tgctgtacgt tattgtgcag caaggatcgt tttagcgcat aatcatcctt ctggtaatgt
    11101 tattccatcg cagcaggata tgaattttac caaaaggata caaaagtgtg gagaaatgat
    11161 ggggatcact gtactggacc acttgatcat cggacgcaaa cgatatttta gtttgagaga
    11221 agaaggaatg atggaagaga agtaagttgc tttcttgcaa aaaaaatgaa gcaagtgtac
    11281 aattatattg taattttgtt tgggaataga agttgaaaca tctgttgcac ctctatcgta
    11341 cacgagcaat gttacaattt aaattagtgc ttttggcacg aggaggatat tattatggaa
    11401 aacggaacag taaaatggtt caacgctgaa aaaggatttg gatttatctc acgtgaagat
    11461 ggaagcgacg tattcgttca cttctcagct atccaaggtg acggattcaa aacattagaa
    11521 gaaggtcaag cagtgacttt cgacgttgaa gaatcagacc gcggcccaca agctgcaaac
    11581 gttgtaaaag cttaatttta tctgtaaatc aaattgatgg tagacatcaa tttttacgag
    11641 agaacaaagc gagtaacaaa aatacctgcc acaagagaca atttctcttg tggcaggtat
    11701 ttttttgtat gaaaaagtaa ataaatttaa gaggctatga aagagccacc ttgtatcaag
    11761 gaataagaac aaacaaaaat ggcttctcat gtttttcatt tgttttctct tatattcagg
    11821 acaaggtgct gatttcataa cctcttattt attcttcatc tggtgtcatt accattggca
    11881 aaatcattgg atgtctttct gtacgttcga ataagaaagg ctgaagcgcg ccagtcatcg
    11941 cttctttcaa tttatattct gaacagtcag gtccattcaa acattctctt aaagcgtgga
    12001 ataagattcg ctgagcttca ttgatcattt ctcctgattc tcgcatgtag acaaatccac
    12061 gagagagaat atctggacca gccaagattt cttttttctt gatatccact gtcgcgacag
    12121 ctaatacaag accttcttct gaaagcaggt gacggtcacg taaaacgaca ttaccaatat
    12181 caccgatccc gctaccatcg atatacacat ctccagccac aaaatgccca gcaggacgcg
    12241 cagaatcgct agttaacgct aaaacatcgc cattttccat gatgaagcag ttttctgcag
    12301 gaacacctac atcttgtgct agagaagcat gtactttcaa catgcggaat tctccgtgga
    12361 caggaataaa atattttggc ttcatcaaac gaagcattaa tttttgttct tcttgtccac
    12421 cgtgaccgga agtatggatg ttattgattt ttccgtgaat cacttctgca ccagcttcag
    12481 acagcaaatt gatcaaatga ttgacacttg ttgtattacc aggaataggt gaacttgaaa
    12541 agatcactgt atcgtctggc tggatttgga tttgacggtg agtaccattc gcgatgcggc
    12601 tcaacgcggc catcgcttct ccttgagaac ctgtacatag gatcatcgtt tcattggcag
    12661 gcaagcgatt gatttcgtgt gcatctacaa atgtgccgtc tggaactttg atatatccta
    12721 aacgttgacc gttgacgatg gcattttcca tgcttcgtcc gaaaacagcg attttacgac
    12781 cagttgccac agcggcatct gctgcttgct gcaaacggaa gatgttagaa gcaaagctgg
    12841 caaaaatgat acgtccttcg atttttgaaa agatcttcaa aatagaatgc ccaatcgttt
    12901 tttctgattt agtaaatgtt ggaatctcag catttgtact atcagataaa aggcacaaga
    12961 ctccttcttc cccgatacga gccattttat gcaagtttgc tggttcgcca acaggagtga
    13021 aatcgaattt gaagtctcca gtcgctacga tatttccaga aggtgttttc accacgatcc
    13081 ctaatgcatc tgggatacta tgggtcgttc tgaaaaagct gacagaagtc tttctaaaac
    13141 ggatgatcgt atcttcattg atctcatgga gctctgcatc tcgaagcaag ccatgctcat
    13201 ctaatttgtt tgtgatcaac gctaatgcga gaggaccagc atagatagga atatttgctt
    13261 gtttcagcaa gtagggtatt ccgccgatgt ggtcttcgtg cccgtgagta atcaccaagg
    13321 cttttacttt gtgtaagttt tgtatgatgt agctgtagtc gggaatgaca tagtcaattc
    13381 caagtaaatc gtcttccggg aatttgatcc cggcatcaat caaaatgatt tcatcttgga
    13441 attgtacccc atacgtattt ttcccgattt cacctaatcc accaatagca aagacgcctg
    13501 tctcgttatt tttgatggaa agtttcatat taaaactcca ctaatgagaa atcagcattt
    13561 tctttttcgt actctagatg acttccttct agaagttgaa cgaattcaat attgtatggg
    13621 gtattttctt ccacacgttg gcgagcgtct acatcgcttt ttgcctcaat gtaaagagat
    13681 tttgtttctt cccgtttagg gttgcgtact tttgtttctt gataataaac tttatagatc
    13741 attgttttgt ctcctttatc tgcgtaaagc agtgatttag ctagttgatt tttttagaca
    13801 acacaaaacg aggggacaag ccacctggtt tttcatatgc tttgactaga atactggatt
    13861 cgagtcaaag agacaagcct cgtttttgct tatctgttcg gatatttttt caaccgtacc
    13921 ttctgtataa aaaatataca acaattaatt gttattctag cataaaacag caaataagta
    13981 tagaaatcaa ctagattgaa agaaaaaatc aatgtttatc atcccgctat aatcataatg
    14041 acttttttat gagagaagtg ttctattaat aggctcgttg tgctatcatt tttagtaatg
    14101 aaaatgtaac aaaagattaa aaggagatga gaaagtgaaa ctaatgtggc attataccat
    14161 gcgttataag aaattcttgt ttttcaattt catatgcgta tttggtttta ttttgattga
    14221 attaggactt cctacgattt tagcacgtat gatcgatgta ggaatccgca atgatgattt
    14281 tgattatgtg aagcaacaag ggatatttat gatcgttatt actgtaatcg gtattatttt
    14341 gaatatcttg ttaggttatt ttggttcgag gattacgact aatatcgtag cagatattcg
    14401 agatgatttg ttcgaaaaga tccaaagtta ttcgcatcag gaatacgaaa atctaggcgt
    14461 atcttcattg atcactcgta caacaaacga tgcttatcag atcatgttgt tcctgcaaaa
    14521 tattttacgt atcggtttta tggcaccaat gatgttcatt gtcagtttgt acatggtcat
    14581 gcgtacaagt gtgacactca gtttgtatgt agtaggtgca ttacctttac tattattggc
    14641 agtcgtagcg attgctaagg tgtctgaacc gttatctaaa aagcaacaaa aaaacttaga
    14701 taaaatcaac agtatcttgc gggaaaatct ttcaggattg cgtgtgattc gtgcattcgt
    14761 caatgaaaag tttgaagaaa aacgttttgc tgtagtcaat gagaattatg cttctagttc
    14821 aaaaagctta ttccgtttga tggctgttgc acaaccgggt ttttatttct tatttaatat
    14881 cgtaatggta ttgatcatct ggagcggggc agtgcaaatc gatgcaggcg agcttcgtgt
    14941 aggagatttg attgcgttta tcgagtatat attccatgcc ttgttctcat tcatgttatt
    15001 tgctagtgtg ttcatgatgt atccaagagc agctgtttca gctggacgta tccaagaagc
    15061 cctagatgcc aaaccttcga ttgtagaaga tccaaatggt atatctgata caaaaactaa
    15121 agggtatatc gaatttcaaa atgtaacatt tgcttatcca ggccattcgc aagagccagt
    15181 gatacgaaat gtcagtttta cagcctctcc aggagagacc gttgctttta ttggaagtac
    15241 cggtagcgga aaatctacgt tgatccaatt gatccctcgc ttttatgatg tgagtgaagg
    15301 aaagatcttg atcgatggag tagacgtgag agattatcgg ctaagcaagt tgcgagataa
    15361 gattgggttt attccgcaaa aagcgctgct atttactgga acgattgcag ataatttgcg
    15421 atacgggaaa gaagatgcta cgcaagaaga aatggaacgt gcagctgaga ttgctcaagc
    15481 ttcagaattc atttctcgaa aaccagatgg atttaatgaa catttatcag aaggtggttc
    15541 caatttttca ggtggacaaa aacaacgatt ggcaatagcc agagccatca tacgccgtcc
    15601 ggaaatctat atttttgatg acagcttttc tgcattagat tatcaaacgg atgcgaagtt
    15661 acgtgctcgt ctgaaaaaag aaacgacaga atctactgta ttgatcgtag cacaacgtgt
    15721 gggaacgatc atgcatgcag ataagatcat cgtattaaat gaaggagaag tcgtcggtat
    15781 ggggacgcat cgggagttgt tggaaaaatg cccgatttat tatgatattg ccgcttctca
    15841 attatcaaag gaggaattag catgaaaaaa accttttctt ccttaaaacg tttagctcga
    15901 tatatcagac cgtatcgtga gacttttctt ttagtgatcc tatttacagt tctgacagtg
    15961 gctttcaacg tggctttgcc atatgttaca ggacttccta ctacagaaat cagccgtaat
    16021 attgccaatg gcgaatcaat caatttttct tatatattca aatgtctcat ttggatcaca
    16081 gttgttggaa tagggtattg tatttcgcaa ttactttctg gtgttttgat gacaaatgtc
    16141 gttcaaagtg ccatgcatga tttgagaaga gacatagaag aaaaaatcaa tcgtcttccg
    16201 gtttcatatt tcgataaaaa ccagcaagga aatattttgt ctcgtgtgac gaatgatgta
    16261 gatgcagtca gcggtgcttt acaacaagct tttattggta tcgtaaatgc gatattggga
    16321 attacgttgg ctgcagcaat gatgttttat atccagccga tgatggcgct gatctctatg
    16381 atcatgattc caacatcgat ctggatctca aaacgagtga tcaatgcttc gcagaaatat
    16441 tttcaaagca tgcagaattc tcttggtgag ctaaacggct acgtccaaga aaatatgaca
    16501 ggttttagtg tattgaaagt atatggacgc gaaaaagaaa cattggaagg attcaaaaaa
    16561 gttaatcaca gcttgaaata ctttgggttt cgtgcagcat tcatttctgg cttgatgatg
    16621 cctctagttc aattaactgc ctatgctact tatattggta tggctgttct aggaagcttt
    16681 tatgttatta ctggggcgat cgttgtcggt caactacaag cattcatcca atatatttgg
    16741 caaatcagtc agccaatggg gaacgtgaca caattgtctt cagttttgca aagtgcatca
    16801 gcggcaacga aacgtgtatt cgagatttta gatgagccag aagaaaaaga aaacaaagta
    16861 gatgcttcac tgccagaaac gattttagga gatgtgacat tcgatcatgt cgattttgca
    16921 tatgatccga agaaaccatt aatccaagat ttgaattttg aagtgaaagc tggtcaaacc
    16981 gtagctgtgg tcggtccgac cggtgccggc aagacgacat tgatcaatct attgatgcgt
    17041 ttttatgacg tagacaaagg agcaataagg attgatggaa tcgacaccaa atcaatgagt
    17101 cgcagtgatg tgcgttcgct atttggtatg gtcttgcaag atgcatggct ttatcaagga
    17161 acgattgcag ataatatccg cttcggaaag cttgatgcga cagattatga agtagttgat
    17221 gctgcgaaaa cagcaaacgt agatcatttt atccgaacga tgccagatgg atatgatatg
    17281 gccatcaatt ctgagggaga caatgtgtct ttaggacaaa aacagttgct gacgattgcc
    17341 cgagcagtgg tctccgatcc taaaatcttg attttagatg aagcaacaag ttcagtagac
    17401 acccgtttag aagcgttgat tcaaaaagca atggatcgcg tgatggaggg acggacaagt
    17461 ttcgtcatcg ctcaccgttt atcgacaatc cgtgatgcag atctgattct agtgatggat
    17521 caaggtcaga tcattgaaaa aggaacgcat gagagtttat tggcacaagg tggattttat
    17581 gaaaaactgt ataacagcca atttgctgag gaagcagaat aagtcatata agaataaaac
    17641 agtttaaaac ttattttttg ttctctattc ttgataatgg taaagtaaag ttatcaagaa
    17701 aagtgaggac acggagatgg aacagttttt aaatgaaaaa attactgaag ccaaaagaga
    17761 agttgatcgt ttaacgcacg tctgtcagac gaagcctttt gattcagctg atttttttga
    17821 aaatgagttt caaatcgaac gcttggcagc acaaatagaa gtgtacgaat taattttaaa
    17881 aaaagtaata gaagaaaata tagatgtaca ataaaaacag gtaaaacgtc agttaccaga
    17941 tactgtaaat agacatctgg cctgagcagg ttttacctgt tttttttctt atgaaataaa
    18001 tatatgctat gataccttta ttcaatagga ttagtttcta caaaaaatga aaggagaaaa
    18061 ataaatatgg aacggtttat agcatcaaat gccacagtga ttggtgatgt gacattgtca
    18121 gaagatgtga cgatctggta tcaagctgtt ttacgcgggg acagtaattg gataaaaata
    18181 ggacaaagaa cgaatatcca agatggtaca atcatccatg tcgatcatga tgcacctgta
    18241 gatattgcgg agaatgtgac ggtaggacat cagtgcatgc tacatggctg tacaatcgaa
    18301 aaaggggcgc tgatcgggat ggggaccacg atattgaatc atgcggttat tggtgagaat
    18361 agtttgattg gtgctggatc attagtaaca gaaggaaaag ttattcctcc taatgtcttg
    18421 gcttttggtc gcccagctaa agtgatccgt cctttgacaa aagaagaaat acaaaaaaac
    18481 aaagaaaaca tccagcatta tgtcgagata ggtcggatgc atgcgcaagg aaaattcaag
    18541 gagcaaagat aggcagtagc atccataaaa taaaaaagga tggtcagttt gagttgacca
    18601 tcctttttta tttggtttag ataagagagc ttaaaaaagc ttcctttgaa acagattaat
    18661 ttaatgaaga actgttttcc atgacttcat cgatcaatcc atatgctttt gcttgttcag
    18721 ctgtcatata gttgtcacga tctgtatctt tttcaatcac ttcaagcggt tgtccagtgc
    18781 gttcagctaa aattttgttt aagcgttcgc gtgtttgcaa aatatggcgt gccgcaattt
    18841 cgatttcagt tgcttgccct tgagcgccgc caagaggttg atggatcatg atctcagcat
    18901 ttggtaaagc aaatcgttta ccttttgtac cagctgtcag caagaagctt cccattgaag
    18961 cagccatacc cataacaatt gtttggacat ctgctttgac aaagttcatt gtgtcgtaaa
    19021 tagccatacc tgctgtaact gaaccaccag gagaattgat ataaagatag atatcttttt
    19081 cagaatcttg agcgtctaag aaaagcaatt gggcgatgat cgaattagca agatcatctg
    19141 ttacttggcc gcttaacatg atgatacggt ctttcaataa acgtgagtag atatcgtaag
    19201 ctctttcacc tcgtgaagat tgttcaatga ctgtaggaat taaattcata atagagttcc
    19261 tccttgattt cgtttagaaa tagtgtacca taatttagtt tctaatacct aaaatgtagt
    19321 atacattttt ggtcaaaaaa ggtcaaataa aaaacttagg caaattagtc gcataaaccc
    19381 gctttatggt atgataagca gagaaacaaa acaaggagga acaacagatt gatagttggt
    19441 attactggcc ttatcggagt gctgacaggt gctgtagttg tctatatcgg catgatactg
    19501 caaatgcgtc acttggaaaa taaagaacag cgtagacgtg aattggaatt gaaagtcaaa
    19561 gaaatcgaga cgctgaatca attaaataaa aagatcaacg agatcttgca aaaacggaca
    19621 acgctgatgg aagaatatgt cagctttgat gcatttgatg attgttatat cacgattgac
    19681 gattttgcgt atctccaatc attttcagcg caaaatagtt tttatctgcc aaattatatt
    19741 ttagacgagc tatttaagaa tatctcccat cgaaaagtga ttttatctcc agatgaaaca
    19801 atgaagattg gtggatatgc ttataaaggc ggacgcgtga ttttagagaa ttttacggat
    19861 agtctgactg aaatgatcaa tgaaaaaaaa gctcagttga agactatgac gcgccagccg
    19921 attggtttct tctcgaaaga tgatgtttgg agctgatatt ttgaagcatt gccgttgcac
    19981 atgagagcgt ggtaatgctt tctttttttc ttaatgatac aatagaactg aacggagtga
    20041 agaaagatgt tacaaatcta tgcccatcgc ggaagcagcg gcacccaccc agaaaatacg
    20101 cttcctgcat ttgcagaagc tgtacgagta ggtgcagatg gtatcgaact agatgtccat
    20161 ctaagcaaag atggttattt gatcgttatg cacgacgaag aagtggaccg gacgactaac
    20221 ggtaaagggc tgattcgaga aaaaacattg gaagaactca aaaaattgaa tgcagggggc
    20281 aaattcagca aagaatttcc agcagctaaa gttcctgaat tgagagaagt gttaggactg
    20341 ctcctccaaa aaaattaccg agggatgcta atgattgaaa ttaaaactga tcagtatgaa
    20401 tatcccggta tcgaagaaaa attagccgaa acattaaaaa gtagagattg gccttttcaa
    20461 catgcatatt gcagctttca tttggattct ttggaaaaaa tcgcattact ggaaccggag
    20521 atacagctgg acttattgat gagtacttct gataaaaaga tccaactagc agcagaaacc
    20581 ccttatatag aaggagtaca tccaaaaaat acttggttgt tcgaacatcc agtccaggca
    20641 gctgattttc caaaagcaat tcgtgcatgg acgattaacg atgaagaaga aatggccaaa
    20701 tgtcaagaac tcaaaataga tggaataata actgattttc cggagaaagc tcttcggtgg
    20761 aaacaatcaa cgaaaagtag gtaaaatatg gaaaaagtat tagtgatcgt cggtccgaca
    20821 gcagtcggta aaacagcgct aagtgtggaa ctcgcacaac tatttggagg agagatcatc
    20881 agtggtgatt cattgcaaat ctataaaaat ctggatatcg gtacagcaaa aatcaaagaa
    20941 gaagagatga ataatgttcc gcatcatttg attgatgtga tcgaacctac tcaacgttac
    21001 tcagccgttg attttcagca ttcaggtcga caattgatta ccgagattgc gaaccgaggg
    21061 cacctaccta tcatagctgg tggtacgggt ctctatatcc aatcccttct atatgattat
    21121 cagttaggag cgacagaaga agcgaatcct gagattagaa aaaagtatga aacgttagct
    21181 gaaacaattg gttcccaagc attatggaat cagttgaaag aaaaagaccc ggcagctgct
    21241 gagaaaatcc actggaacaa tcaacgcaaa gtgataagag ctctggaagt tttagagacg
    21301 acaggacata gtatcacggc acctaaagaa gagccaaagc aattgtatga ttacctcatg
    21361 attggattag atacgaagcg tagtattctt tatgaacgaa tcaatcaaag agtcgatttg
    21421 atgctagcag aaggtttagt agcagaagcg cgtaaggtgt atgagcttgg agaagtccag
    21481 gccagtcaag gtattggata taaagaattt ttcccttatt ttgaagggaa agaaacattg
    21541 gaagaagcaa cagaacaagt caaactacat tcgagaagat acgcgaaacg tcagttgacg
    21601 tggtttcgta accgtttgga tgcacagtgg tttgatctta taagtgagcc aaatcaaaaa
    21661 agtcagattg agcaaacaat caaaaaatgg ctggaggcgg aataaaatgg aagaaaaagt
    21721 gatcatcgta ggggtagaaa ccgaagcaaa ccagcgttac ttttcagagt caatggaaga
    21781 gctagttcag ctgacgaata ccgcatcagg agaagtcgta ttcacaatta cacaaaagag
    21841 accacaagtg gatcggcaaa cgattatcgg taaagggaaa ttacaagaat tagttcaaca
    21901 agcggatgcg catgaagcgg atttgatcat ctttaatcat gagctaactc cgagacagag
    21961 ccaactgatt accgatgctg ttggtcttcc ggtaattgat cgcgtgcagc ttatcttaga
    22021 tatttttgcg atgcgtgctc gttcgaaaga agggaagctg caggttgaac ttgctcagtt
    22081 agaatacctg ctgcctcgtt tagtagggca agggaaaaca ttatctcgtc ttggcggtgg
    22141 gatcggaaca agagggccag gtgaaacaaa gttagaaaca gaccgccgac atatacggaa
    22201 taaaattttt gctgttaaga aagaattgaa agaagtagaa gctcatcgag agcgcaatcg
    22261 ccaaaaaaga aaaaatagcg agatttttca gattggactt attggctaca cgaatgccgg
    22321 gaagtcaact atcttgaatc tattgacaca agcggatact tattcgaaag atcaattgtt
    22381 tgcaacgtta gatccattga ctaagagatg gcgttttgct gaaggatttg agattactgt
    22441 aacggatacc gtcgggttca tccaagacct gcctacgcaa ctgatcgatg ctttccattc
    22501 tacattagaa gaaagtcaaa atatggatct tttgctacat gtagtcgatg ctagttctcc
    22561 agatcgtatt ttacaggagc agactgtctt aaaattgatg gatgaactga atatgaaaga
    22621 aatgccgata ctgactgttt acaataaggc agaccagatc gacccagcga tgttcacgcc
    22681 tacgctattc ccaaatgtat tgatttctac tcagacgaaa gaaggtaaga tggcgttgat
    22741 cgaagcaatc aaacgtcagc tgatggaact aatgacccct tatacacttt ctgtgccaag
    22801 caacgaagga cagaaattaa gcgagttgag aagacaaaca atggttttgg acgaagcgta
    22861 catggaagaa acaaacgaat atgaagttaa agggtttgca aaaaccaatt caaaatggtt
    22921 aagaaaaaac caataaaatt ttattttttt aa
//
LOCUS       DADLIO010000045        22719 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.045, whole genome shotgun sequence.
ACCESSION   DADLIO010000045 DADLIO010000000
VERSION     DADLIO010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22719
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.045"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(11..1942)
                     /locus_tag="JOX41_001833"
     CDS             complement(11..1942)
                     /locus_tag="JOX41_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAY6449576.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(1960..2874)
                     /gene="pfkB"
                     /locus_tag="JOX41_001834"
     CDS             complement(1960..2874)
                     /gene="pfkB"
                     /locus_tag="JOX41_001834"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HAY6449577.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(2871..3623)
                     /locus_tag="JOX41_001835"
     CDS             complement(2871..3623)
                     /locus_tag="JOX41_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAY6449578.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(3782..3991)
                     /locus_tag="JOX41_001836"
     CDS             complement(3782..3991)
                     /locus_tag="JOX41_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449579.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(4002..5330)
                     /locus_tag="JOX41_001837"
     CDS             complement(4002..5330)
                     /locus_tag="JOX41_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449580.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            complement(5695..6282)
                     /locus_tag="JOX41_001838"
     CDS             complement(5695..6282)
                     /locus_tag="JOX41_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HAY6449581.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(6365..7615)
                     /gene="clpX"
                     /locus_tag="JOX41_001839"
     CDS             complement(6365..7615)
                     /gene="clpX"
                     /locus_tag="JOX41_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HAY6449582.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(7862..9151)
                     /locus_tag="JOX41_001840"
     CDS             complement(7862..9151)
                     /locus_tag="JOX41_001840"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HAY6449583.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(9305..10237)
                     /locus_tag="JOX41_001841"
     CDS             complement(9305..10237)
                     /locus_tag="JOX41_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449584.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHQVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(10394..11053)
                     /locus_tag="JOX41_001842"
     CDS             complement(10394..11053)
                     /locus_tag="JOX41_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HAY6449585.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(11056..12081)
                     /gene="sppA"
                     /locus_tag="JOX41_001843"
     CDS             complement(11056..12081)
                     /gene="sppA"
                     /locus_tag="JOX41_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HAY6449586.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(12094..12384)
                     /locus_tag="JOX41_001844"
     CDS             complement(12094..12384)
                     /locus_tag="JOX41_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449587.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            12793..14598
                     /gene="glmS"
                     /locus_tag="JOX41_001845"
     CDS             12793..14598
                     /gene="glmS"
                     /locus_tag="JOX41_001845"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HAY6449588.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(14670..16025)
                     /locus_tag="JOX41_001846"
     CDS             complement(14670..16025)
                     /locus_tag="JOX41_001846"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HAY6449589.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(16049..17218)
                     /locus_tag="JOX41_001847"
     CDS             complement(16049..17218)
                     /locus_tag="JOX41_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449590.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(17215..18102)
                     /locus_tag="JOX41_001848"
     CDS             complement(17215..18102)
                     /locus_tag="JOX41_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HAY6449591.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(18291..21983)
                     /gene="nifJ"
                     /locus_tag="JOX41_001849"
     CDS             complement(18291..21983)
                     /gene="nifJ"
                     /locus_tag="JOX41_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HAY6449592.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            22182..22703
                     /locus_tag="JOX41_001850"
     CDS             22182..22703
                     /locus_tag="JOX41_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HAY6449593.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
BASE COUNT         6326 a         4932 c         4041 g         7420 t
ORIGIN      
        1 ttttttattt ctatgcttct gctactgcag gagcttttct caataaacca taaatcacac
       61 cagatacgac tgctccgata gcaataaaca ccaaatacat gaccgggtga ctcagtaaga
      121 atacaacgaa aatcccgccg tgaggagcca gtaatttgat tccgaaagct ccgactaatc
      181 cgccagttaa agcagaacca ataataaaac ttggaatggc acgaatcggg tcagctgctg
      241 caaatggaat cgatccttcc gtgacaaacg atagtcccat cacgatgttc gtcaaaccag
      301 catcttgatc tgttttgctg aatttattct taaacaaacg tgtagcaacg aaaattgcca
      361 atggaggtac cattcctcca gccataacag aagccatcac gacacttccg ccagttgcaa
      421 cagtcgtagc taaagttgct gtaccaaaca cataagcggc tttgttgatt ggaccgccta
      481 aatctgccgc catcattcca gctaataatg caccaagtaa agcagcattc gaaccactca
      541 tacttgtcaa gaaaccgttc aatgcatcat tgattgcttt catagggaca ttgaccagca
      601 acatcaagaa accagtaatc agtaagccaa acactggata aaagaggatc gttttaattc
      661 catccaatga ttttggtaag ttcttgaata atttacgtaa aaatacgatg acataaccag
      721 ctaagaatcc accaatcagt gcacctaaga atcctgcacc gcctgtatta gctaatgcac
      781 cagcagcaaa tccaacgatc aaaccagggc ggtcaccgat acttgaagca ataaatcctg
      841 ctaataccgg cagcatgaaa ccaaatgcag cttgtccgat ttggttgaac cagctagcag
      901 cttgattgta attccctaga tttgataatt gatcatgtgg cacgccaata aattggtcga
      961 tcatgaaaga aagcgcaata gcgattcctc caccaataac gaaaggtaac atgtgtgata
     1021 cgccgttcat caaatctttg taaattcttt gtccgatagt accatccgca tttccttctt
     1081 ctgaactgct ttcttttcca tcaccatgga atactggtgc agtaccacta agggctagat
     1141 tgatcaactc ttctggttta cggataccat cactgacagg acgattgatc agttcttttc
     1201 cgtcaaagcg attcatctct acttttttgt ctgctgcaac gattacacct tctgcacggg
     1261 cgatgtcttc agcagtcaat cggtttttga ttccttctga accgttcgtt tcgactttga
     1321 tctccacacc catttctttc gcttttttct tcaaagcatc ttctgccatg taagtgtgag
     1381 cgatccctgt tggacaagct gtaacggcaa caacgaattt tctttctgga tgagcagaag
     1441 cttctgcagc ttgtgtttct tgttctgctt tttcttctgc ttctttttgc tcttcagctg
     1501 tttggaacaa gtcttggact tcttctggtg tatttgcttc ttttaatttt cctacgaaat
     1561 ctgcatcaat cagcaatcga gatagtgctg ctaatgcttg caaatgtgtg tcgtttgcgc
     1621 cttctggagc tgcgatcatg aaaaacagat aagttggctg tccgtctaag gcttcataat
     1681 ctactccttt ttggcttttt gcgaataaaa ctgttgcttc tttaactgca ctgtttttcg
     1741 cgtgaggcat ggcgattcca tcaccaagac ctgtagaagt ttgtgcttcg cgggctagaa
     1801 ttccttcttt atatgtttcg atatcggaaa tccggccggc atcaaacatt ttttggacca
     1861 tttcatcgat tgcgcctttt ttatcagtcg cttgcaaatc catgatcatc gcttctttga
     1921 ccattaaatc cttgatattc atgattatcc tccttgaaac taatcaattt ttgtgatttc
     1981 aacttctggc agcaactcat caatcaattc gcgagctgcc aagtcatcag aaaaagctgt
     2041 tgcgcttccg caagcaactc cccatttaaa ggcttcgatt ggatctttcg tacggctgta
     2101 agccccaata aagccagcaa tcattgaatc ccctgcacct actgaatttt tcaatgggcg
     2161 aactaataca ttcgttttat aagttccttg ttccgtgaag agcaaagcac cgtctccagc
     2221 cattgagatc agcacattct gtgccccttc agctagtaat tttttcccat acggaatgat
     2281 ttcttctaca gattggaagg ttgtgttgta aagctcagct aattcgtgat tgtttggttt
     2341 gatcaacaac ggtttcttaa caagtgcatt ttttaggtca tcacctgttg tatcaatcac
     2401 gaaatctgca cctttttctc gaatgatatc aatcagttct tgataaaatc cttttcgcag
     2461 gctagctggc gcgcttcctg acaatacgac gatatctcct tgtcctactg ttcctaatgc
     2521 ttgcttcaac tcatcgattt cttcatctga aatagatggg cctaagccat tgatctcagt
     2581 ttcagtgtct gattttagtt tgatattgat tcttgtatct tcttttacgg ttgtgaacaa
     2641 agactggatt tgttcttttt caagccactt cgaaataaat tcgccagtga accctcctaa
     2701 aaaccctagt gctgtagatt gagaatcgat ccgtttcaaa atacgggaaa cattgatccc
     2761 ttttcctcca ggtaacttga agtcttcctt cattcggttc aaatcgccta gttttaaccc
     2821 atctacgcgt acgatataat caattgatgg attaagtgtt actgtgtaaa tcattgtatt
     2881 gcctccttaa ttgttgtctt ttcacggaat tcattaacga attctaatgg acaacgctcg
     2941 gttatgatcg tggctgcttc caaaggtgca acagaggtga aggacaactg gttgaatttg
     3001 gtatgatcaa tcaatacaaa tgtctcttcg gaatttttca tggctaaacg tttaacagct
     3061 gcctcttctg gatccggagt cgtgaatcct tgttcaagat gggcaccgtt cattcccata
     3121 aatgctttat taaaatgaaa attttttagt tgttctatcg cattagatcc taaaacagca
     3181 ttagttgcca gctttatcgt tccacctaaa ataatggtag caagctccaa atcaactaaa
     3241 tttgccgcat gttgaacgga atttgtcact actgtgatct gttttccttg cagaaaagga
     3301 atcatttcta acgtagtaga gccagcgtct aaataaatga catcttcgtc attaatggtt
     3361 tcagctgccg atttggcgat ttgctgtttt tcgtgaacgt ttttgagtga tttttcactc
     3421 atattctgct caaaattcaa taattgctct ttcttagctc cgccatgaac tctttctaga
     3481 aacccactat tctccagctc ttgtaaatca cgtcttatcg ttgattcaga agcattcaaa
     3541 aggtttacaa gatcttgtga tttcacgatt ttctgctgtt caagcaagtc taggattttt
     3601 tgtctgcgtt cctctgtaag cattttcacg atcacctcaa tacaaataat agcatatttt
     3661 ttttctacta gcaatataaa tcagtcaaaa acgttcataa aaattataaa tcagtcaaaa
     3721 aaaaataaaa aaccagtcag aaagactggt tttttatttt tttgtctatc atcaagccgt
     3781 tttatcgttt tttattttcg cttcttgttt ttttcatata aacagaagca ggttttcttt
     3841 ccttatgaag aagataataa taaagtccca tcccgccaaa catgaccaaa aaaccgatga
     3901 ctgatcgaat aggaaaatta ggaacaaaaa agagacagac ggataataat gatgccggaa
     3961 ccattattcg ataatagagt tgtttatcca ttttcttcac ctcatatttt ttgtaaagta
     4021 atcaattgtt ctaattctcg gtaatctaaa aattgcacac gcagatgctg ctcacctttc
     4081 ttgacatcga attggatact tcgccgcttt ttctttattc gtttgaaggt aacatcagag
     4141 agtctatgtt tgatttcctt taacggtaat tctgacaggg attctgaagg aacatagatt
     4201 cttaaggata aaagatactc ttgatatttt tcatctgtta cctctacttc tagatattcc
     4261 ctaatataat aacaataagc ttcgattcca ttatccaaag caacagtcgg atcgataact
     4321 ttatagcaca tcatgcgtga tcgattctcg tcaacccaag gaaaatacgc ctgagcattt
     4381 agtgttccgc gaacacgcct ttctttataa tctccttgtt ggatatcata actttttgtt
     4441 acaaaaaatg aagcattctt tttaggaaca ggttgcattt gtgcattctg atactggaca
     4501 gattggatcg tatggtcagt gtaaatgtat tcaacgaatg gcggtttcaa taaaccgaca
     4561 ccattgtccc aagcaagatg atcaaaccca agctggtccc taaaatagga ttgaaacatt
     4621 tgattgtttg gcttttgcca gttaaagggg tctcgataaa gctggataca tatgacttcg
     4681 ttttctaatt ccttcacttt ttctacttgt tggatgtcga gaaaaatcgg tttagggatg
     4741 atttgatgat aatagcgact ataatacatt tcccaacacg aagtgaaaca taaaccttgg
     4801 taaaaaagat cgtatcctgg aaattggttg caatcgacta ctacttcccc gttttgttgt
     4861 ttcattttag gtaaatgttc gatttcatcc tttttctcaa acaatagccg ttgagagatc
     4921 tgttttgtat tgtgatagat aaactcgcta taagctcgca tataggcgaa caccccatga
     4981 gcaatcattt ttttctgaat gaagtctcga atcaaaaatt gcttttcttt gaaaacagag
     5041 atagacaata cattttttat caataattga ttatcttcca agcgaaaact acattcgttc
     5101 tcgtcatttc ctacaactaa ccaactttcg tctcttaccg atgctagcat tattttttct
     5161 tgaagctttc gaagatcata cggatccgct tgttgtgtga aagagcggat aaatgttggc
     5221 tggatcaaca gacgtgtcaa aatagcccaa tcgcttattt cctgtttttt ttcttcttca
     5281 tttaagtctg tgagctggat agtcatcaat aatttatctt cgccaatcat tttctcacct
     5341 ctttcaaatc tttttataat ttaattataa ccaatgataa agaaaaacta aaactttatg
     5401 tcttagaaac caatttggac gattacatga tagactaagt aaaaagaaac aaagaggtgt
     5461 ttacaatggg gttgaaattt gaacgtacag ataatttaga taaacttttc gaatcatttg
     5521 ctgtcgatcc ggaaaaaaca gttgcaccaa aagaagagat cgatcgattt ctaaaaccac
     5581 agccacaaaa tgaaaagaaa aaagacaaga aacaaaagta agttaagctc aaaaaaagac
     5641 ttaccagcca aacttttatg aaagagtttg actggtaagt cttttttatt ctttttatga
     5701 ttcaattgct tgttcgattg ctgcccacgc ttcttctttt ccctgttttg taacggaaga
     5761 aaagagaata aacgtgtcat tgcgatcaaa atccaacgct tttttgattt cgctctcatg
     5821 cttgttccat ttaccacgag ggatcttatc tgccttagtg gcaacaacaa ttacagggat
     5881 atcataatac ttcaaaaatt gatacatctg gatatcttct tgagaaggct tatgacgcaa
     5941 atctactaaa gaaacgaccg cacgtagctg gtctctagtc gttaaatatg tctcgatcat
     6001 ctttccccat tttgctcgct cagttttgga tacttttgca tacccatatc ccggaacatc
     6061 gacaaaatgt aatgcgttct cgatcaaata aaaattcaat gtctgggtct ttcctggctt
     6121 accggaagta cgggctaaat tctttcgatc aatcaatgtg ttgataaaag aagatttccc
     6181 tacatttgat cgtcctgcca gagctatttc tggcaattgt gtatctggat attgttttgg
     6241 tgccactgca cttatgataa tttcagcttg atggactttc atggtctctc tccttaacaa
     6301 ggtgatgaat aaagcaagcg gctgtcgcaa aagccaaaat gacttttacg gcagcctctt
     6361 ttcatcaacc cgcttttttc tctgaatctt tatagattac tgttggctca ccagacaatt
     6421 cagctgcttc ttttgtgata atcacttttt cgatgttttc atttgaaggg atatcaaaca
     6481 tcacatccat catgatttct tcaatgatgg aacgaagtcc tcgagcaccg gtattgcgtt
     6541 cgattgcttt tttcgcaatg gctctcaacg cttcaggttc gaattcaagt tcggtattat
     6601 ctagagaaag aagtttttga tattgtttga ctagcgcatt tttcggctca gtcaagatcc
     6661 gtaccagatc atctgttgtc aatttctcta aagctgccat aacaggtaat cgtccgataa
     6721 actcagggat caatccgaat tttagtaaat cttcaggaat gatatgctgc atgacacttt
     6781 cgtcttcaga aagtttttgg ttttgtgtac caaatccaat cgtcttttcg cccatacgat
     6841 tcttcacaat cgtttcgatg ccatcaaatg caccacctac gatgaacaat atgttcgtcg
     6901 tatcaatctg aataaattct tgatgtggat gtttacgtcc gccctgaggt ggcacacttg
     6961 caacagttcc ttctagaatt ttcagcaagg cttgttggac accttcgccg gaaacgtcac
     7021 gagtaataga tacattttcg cttttacgcg caattttatc gatctcatca atatagatga
     7081 tccctttttc tgcaagttcc acattgtaat cagcagattg aagcaattta agcaaaatgt
     7141 tttctacatc ttcccccaca taaccagctt ctgtcaaact tgtcgcatct gcgattgcaa
     7201 aaggtacatt caatgttttt gctaatgttt gtgctaaaaa tgttttacca gaccctgtag
     7261 gtccgatcaa gcagatattg cttttttgca gttcaacatc atctgtgttt tcttgtgctt
     7321 gctgattgac acgtttatag tgattgtata cggcaacagc taacgagcgt tttgcgcgat
     7381 cttgtccaat cacgtagtta ttcaatactt caagaatttc tagtggttta gggacttcag
     7441 tgaattcgcg tacagcttct tcataaaatt cttcatcaat gatttcttta cataggtcga
     7501 tacattcatt acagatgtag acccctggac cagctacgat ctttttcact tcttcttggg
     7561 ttttcccgca aaaagaacag cgtacggtct cattgctact tggattgtca tacatggtct
     7621 tcacccctta acttgcaaaa agtatgcaag aaactatcaa agactttaca gtcttttact
     7681 atcataacat agtttagtaa aaagaaaaag tgtttaacaa aggatcaact gacctatacc
     7741 tttgcatttt ttactcttaa caaaaaataa ggaactgtga caaaatcgtg tcacagtccc
     7801 ttatttcgaa taaacaattt tctagaagta gcttcttcag aaatgattta ttacttgatt
     7861 tctattcttt cgcttctgtc gctgtacctg tgatcaattc gattgctttt ttcattgtca
     7921 catcatgttc cagcatatct tctgtcaaca cgcgtttgat ttgttcgatt ggcatgttgt
     7981 atgtttctga taattcttgg atttctgcat tgatttcttc ttctgttgct tgaagatttt
     8041 cagcagctgc aattgcttcg atcacaagat ttgttcttgt gcgcatttct gcttcacctt
     8101 cgaattgttt atgcaagtct tcttctgtag aaccagttaa ttgatagtac atttcaggag
     8161 agataccttg acgttgcatg ttgttcaaga attcgtccat tgaacgatgt acttcatcat
     8221 gaaccatcac gtgtggcaat tcaacgattt ctgcgttttc aacagccata cggatcgctg
     8281 cttcatcttt tgcatcgtcc gctgcttttt cttttgtttc tactaattct ttgcgatatt
     8341 tttctttcaa ttcgtctaat gttgatactt cgtcatcaac atcttttgcg aattcgtcat
     8401 ctaattcagg cacttctttt gcttttactt catggattgt cactttgaag actgcttctt
     8461 ttccagcaag atcttctgct tgataatctt ctgggaaagt tacatttaca tctagacttt
     8521 cacctgattt atgaccaact aattgatctt caaaacctgg aatgaatgag cctgaaccta
     8581 attcaagtga gtaattttcg ccttttccgc catcaaacgc ttcgccatct acaaagcctt
     8641 cgaagtcgat tactactgta tcgccatttt cagctgcagc atcttctttg ataactaatt
     8701 cagcttgtgc ttcttgttca cgtttgatac gtgcatccac gtcagcatct gttacttcac
     8761 ggtcttgttt ttcaacaact agatctttat attgtcctaa ttttacttct ggtttcactg
     8821 ttacttcagc agtgattacc cagtcttgac ctttttccat gctttcaaca tcgatttttg
     8881 gttgagaaac aggatcgatg ccagcttctt tgacagcagc ttcataagct tctggtaata
     8941 cagcattcaa tgcatcttca tataaagctt cttcaccgta catacggttg aatacttgac
     9001 gagaaacttt ccctttacgg aatccaggta cgttcaagct ttttttcact ttattaaacg
     9061 cagttgttaa tcctttttgg atttcgtctt gcgcaatcgt aaattttaaa acaccatcat
     9121 tcgtgccttt tttttcaaat gttgcagtca tttaattccc tccgagttta gaaattcatt
     9181 ttatacatca aaaacgtttc atgcatacct ttaaatagta cactaaccct ttcaaattgt
     9241 aaacatattg aatggataga atccttgttt ttcataacat ttttatcttt ttcactgata
     9301 aaatctaatg gaagaagatc atttgctgca aaattttttc tctttttttt aaaaaatctt
     9361 gtttttcatc ttctgtacct tcatacatcg tttttcctgt acacgcctct acagtcagtt
     9421 gaaaccagcg cttcgggtct tcgatgtatg tatcatagac aggataaaca attgcagatt
     9481 gcaacgtgaa ttcttctttt aacacggaac taagcagcgc atcttcattc ccgtaacgat
     9541 ctgaaaatac acataattgc tggtaacttg cctgctgctg cggctttggc agatcttttg
     9601 gtatgacttt gactaacttt tcttcaatcg tcaaatagaa aacttgatgg cattcgttca
     9661 attgcctaag tgtctccagt aattttgccc ttgctaaaat atggacctct ggcgatacaa
     9721 taagtttact cgctgtttgg ataaactcat gataaggaag ctgttcgatc tcatcaatag
     9781 acgcaagctg acgtgcaggt tccaacgaag gaagttcctc cgatttattg tggagtgcct
     9841 tgatcttctg cctctccatt tgtccggata attcttctgc aaattggatt ttttcaatga
     9901 cccgctgctc gaaagcttca taaaaatctg tacttgctat caattttcta gcatataaaa
     9961 aatcttgtgt actgattaac aagtcaaaat aaaattcagc aaactcctca ttttgaagat
    10021 actgtttttc atgcaagagt gcttgcttca atgcttcttt tttctcgtcc aactcgtaaa
    10081 gacaaaaaac aagcaggcta ttagcctcaa agctttcttt caactcgtaa gctcgttgaa
    10141 ataattcttt tgcctgctga tattgctggt ttgctagtgc ttgttgtgcc actcgcatta
    10201 aattctcata tttttctgga aaatcaatcg gcttcacgca gtgtcctcct cttgctcata
    10261 ttcagctcat gttcaatagt agcaaaacaa aaaaagcatg acaattaaaa ataactgaag
    10321 caccctctaa aagctagatt ttagatctga cttttagaag gtgctttcaa ctgttactgc
    10381 tttttattgc tcatcagctg ttgacttcct ggttgaacgc tttgatcaga ttgatcgtaa
    10441 caacacttgt attagtgaaa aaatcgccca gatgttgctt tttctgatta aagactgctg
    10501 gaagataccc taacatcagc aaaggaaatt ttagaatgaa ccggcaagca ccttctctaa
    10561 ctaaaacggt tgaccagcta agttcttctt catcaaagct gatgactcga ataccaaaga
    10621 tcattttccc aatcgtttgg ccatgattga atttcgtcaa taaaataaaa tacgctagat
    10681 aaataagtaa ggctgtgaat ccgtagagac tcagataaga atctgaaaaa ttaagccaac
    10741 ctagattttt ggcaatacca agtgttaaac gcgtaatagc tccgatacac aaaagatcga
    10801 ccaagaaggc aaacattcgg ataaaaaaac ctgcatagaa atacttagga aaatcatttg
    10861 cttttggcgg ttcatttctt gtgtccgtat actttttcca tttacgttgt ttctttttga
    10921 tttcttcggg cgtcaaaggc tctctttcaa aagagctcag taccttttgg gaaaagttgg
    10981 agtcaggtcc tacagcaggc tgctgttgct tatctttttc ttgttcctta ttttcatttg
    11041 aaagctctga catgcttact cacctccgta ataatacatt gcttttggtg attccgctgt
    11101 ccctagattc tcaagaacgg ataagatctg actagtctca gaaggcttca atccctggaa
    11161 ttctgctagt ttacttccta accatgtact agcaaaccca gatggcgtgg aagaatattc
    11221 tactagttcc gcatcttcaa gctgttgttc ctttcgtata gcttttaaag catcttcagg
    11281 aaatcccaat tcatcgacta aacctacttc ttttgcttgg acaccatcat aaatccttcc
    11341 atcagcaatt tttttgactt cttcttcaga tttattccgt ccctcgctga cgattgctac
    11401 aaaacgacta tatgcgctgt cgatatatgc ttgaagcacc gcttcttctt cttttgtctc
    11461 tggtcgcgtt cctgaaccca tatctttcaa cgctccgctt ttaactgttg tatcttccac
    11521 acccagtttt tctagaagtc ctgaataatt caatcctgac atgatcacac caattgagcc
    11581 ggtcactgtt tcttctgttg caaagatttt atctgcttga gcagaaatat agtagccacc
    11641 gctagctgcc atgtttttca tgctgacata cattgggata tcatgttctt tacgaatcgt
    11701 atccaatttc ttagcgattt ccgcactttc gtagacaccg ccaccaggag aatttacttc
    11761 taaaaagata cctttgactg ttggatcttc ttcaatcgcc ttcagttgtt ccataaaatt
    11821 tttatgattg taaccttcag aagcaaataa acctgaagac cctcccgcag caatcgttcc
    11881 atctactgat aattttacga ttttttgcgt actgtctccc tcttccaaca catttggagc
    11941 tagttcttca tccccatata accaactgtt caatccctca atttgatcgt tttcctgagg
    12001 cttagtcaaa ctagctgaaa ctaacgaaac cacaaataat cctgcagcaa tcagaactgc
    12061 tgcccaacgt cttttattca ttctttctcc tttctaatac aagtttttta tgacgatcac
    12121 agtttctgac tgctcagaag tgtcgaaccg ctctgctttt tcttcccgcg catacccgga
    12181 aaacgactct tttgttaatt catcttctac cgtaaactca cgagcttgag caacttccaa
    12241 ggcatcaggt gcgatttctt ggatgctatc ccagccagta tctaaaaata ttttcgtatc
    12301 atctgataca ccagctgatg cttcgaattt ggacaattgt ttttttaaca ttcccagtgt
    12361 catgatctca atttttgaat ccatttttac tcctcctcta tccgattact ttctattgta
    12421 ccgaactcct gaaaaagatg atagataaaa acccattatt ttttgacata aaaaggacat
    12481 ttgacaaaga atttgatata taccaattta ttttttattc tttttttgtt gacaagaaca
    12541 ttcgcaaaag gttatgattt taaatgtttc cagataaaaa acaaaaagga ggatagttat
    12601 accttttagg atagcgccag gtctgtgtaa acagatgacg aggagagggt ttatcgaaag
    12661 attcggcgga tggccctagg gactgcactc tacagaaaat ccacaaaaaa tgtctgcaaa
    12721 gataaaacaa aaggattttc ctgcagctgg aagcattcat acgaattcat tatagaaagt
    12781 aggatgtttt ttatgtgcgg aattgttgga atgattggat taaaaaatgt aacaccagga
    12841 ttgattgacg gtctagaaaa attagaatac cgtggttatg attcagctgg tatctttgtc
    12901 tcagatggca caactgatta tctggtcaaa gcacaaggca gaattcaaaa tttgaaaaac
    12961 aaaataaata ttgatactac aggaaatata ggtattggtc atacacgatg ggcaactcac
    13021 gggcaacctt ctgaagaaaa cgcccatcca catacttccc aaagtggacg cttcgtgctc
    13081 gttcacaacg gcgtaatcga aaactttgaa gaacttaaaa ttgcttattt agcaaatgac
    13141 cactttattg gtgagaccga tactgagatt atcgctcatc taattgaaac tttcgcgaag
    13201 gatactacaa cgcaagaggc gtttttaaaa gctttgcggg tcatcaaagg ttcttacgct
    13261 ttcgctttga ttgatcggac agcacctgat gttatttacg tcgctaaaaa taaaagtcca
    13321 ctattaatcg gactcggcga tggattcaat gtgattgcca gcgatgcaat ggctatgctt
    13381 gctcatacga aggaattcgt tgagattgaa gatgaagaga tggttaccgt cacatcagaa
    13441 aaagttatta ttcaaaattt tgcaggtgac atcgtagaac gttcttcatt cgaagcacaa
    13501 gtagatgctt cagatatcga gaaaggtacc tatccttttt atatgctgaa agaaatcgac
    13561 gaacagccta ttatcatgcg tcgtatcgct caaaaatacg taacagaaga caatcgtgtc
    13621 tctcttgatc aaaagctggt cgatacattg tctgatagcg atcgaatcta tatcgttgct
    13681 tgcggaacta gttaccatgc ggggttagca ggtaaacaga ctttggaaaa attgacacag
    13741 attcctgttg aggttcattt agccagtgaa tttggctata acacacctct tctttcaaaa
    13801 aaaccattct ttattttctt gagtcaaagt ggcgaaacag cagacagccg ccaagtgctg
    13861 gtaaaaatca accgtctcgg ctacccttca cttacgatta caaatgttgc tggttctact
    13921 ctttcgcggg aagcatcctt tacactgcta ttgcatgctg gacccgaaat cgcagtagca
    13981 tcaacgaaag cttatactgc acaaatagct gtactaactt tattagccaa agctatcggt
    14041 gataaaaaag aatttgaaac ttctcttgta ttcgatatca ctcatgaatt gagtttagtt
    14101 gctaatgcga tggaatcggt catcgcccaa aaagattatt tagaagagtt ggcagaagta
    14161 tatctcagcg atacaagaaa tgccttttac attggacgtg gtgctgacta caacgtttct
    14221 cttgaagctg ctttgaaatt gaaagaaatc agttatatcc aggcagaagg ttttgccgct
    14281 ggcgaattga aacatggaac gattgctttg atcgaagaag gaacaccagt gatcggaatc
    14341 atcagtgaag aagtgactgg tgcgcatact cgaggaaacc tgaaagaagt cgaaagccgt
    14401 ggcgctaaaa cactagttat tgtctcagag ggattagaaa aggaaagtga ccagctggtg
    14461 ctaccaactg tccaccctta tctaactact ctaaccacag tcgtaccgac tcaattactt
    14521 gcatattacg caacgctatt acggggattc gacgttgaca aaccacgtaa tttagcgaaa
    14581 tcagtgacag tagaataata aaagaacaag gaccagtgtc agacatctga cactggtcct
    14641 tgttctttta ttttttatga aaatatctct taatccagtc cgatttcttc tttgactact
    14701 gccgcgattt tatcgacata gtaattaact ttctcatcag taggcgcttc tgccatcact
    14761 cgaagtaatg gttctgtacc ggaaggacga actaggattc ttccttctga tcccatttca
    14821 gcttctgcct cttcaatcac ttttttgatt gccggaacat ccatcgcacc gtttttatca
    14881 cttacgcgga tattcactaa tttttgcgga tagattgtta cctctgctgc aagctctgat
    14941 aatttcttac ctgtctgttt catgatattc agtaactgaa ttcctgaaag catcccatct
    15001 ccagttgtgt taaaatctaa gaaaatcatg tgcccagact gctcgccgcc aaagttataa
    15061 tcgtttttgc gcatttcttc tacaacgtaa cgatcaccaa cttgtgtaac gacatctttc
    15121 aaaccgattc cttccaccgc tttgtggaat cctaagttac tcatgacagt cgtaacgatc
    15181 gtatcttttt tcaatcgatt tttttctgcc aagtatttag cacagataaa catgatttta
    15241 tcaccgtcga caatgtttcc aagttcatcc accgcaataa tacgatcgcc atcgccatcg
    15301 aaagctagtc cagcatctgc tcctttttca acgaccatct cagctaaacg ttctggatgg
    15361 gtagagccta cgccgtcatt gatatttaac ccgtctggat ttgtgcccat tgtataaaaa
    15421 tctgtttcaa gatcggcaaa caaacgatta acacttgttg aagttgctcc gtttgctgca
    15481 tcgacacaaa tggtcaaacc ggaaaggtca ccgttaatcg tttgtacaag gaattgagaa
    15541 tatttcaata agccttctgg aaattcttct acagttccca atccttcagc tgatggacga
    15601 ggcaattcat ccacttcagc atctaataat gcttcaattt ctagctcttg gtcatctact
    15661 agtttaaaac catctgcacc gaaaaatttg attccattat cttgtgctgg attatgagaa
    15721 gcagaaatca tgacccctgc gcttgctttt tgcaaacgtg tcagataagc aacacctggt
    15781 gtagagatca cacctagctg gaacacttcg atacccaccg ataaaagtcc tgaaatcagc
    15841 gcttcttcta acatttgacc tgagattctt gtatcccgcc ctactaacac gcgtgggcgt
    15901 tttccttctt cttcatgctg gcttaggaca taacctccgc accgtcccag cttaaatgca
    15961 agttctggcg taagttcctt gttggcttca ccgcgtacgc cgtctgttcc aaaatattta
    16021 cccatagttg taaaattact cctttaactt aattttctga ggaatttgtt ctgctcattt
    16081 gtgttgattc gcttgtttct gatgtttctt ctgtacttgt ggtcgagctg cttgtcccag
    16141 attccgaact ggaagaaatg gttgttgtcg atggttccgt tcctgaatca gcagatgaaa
    16201 tacttctact cgtacttgta ttttcttgtg tccgactgct cgtcgaagca gagctactgc
    16261 ttgacgtttg caacacgggt gtaatctcca cactaactga ttcgggcttg atacttaacc
    16321 cctcttctac tggtatttca attttacgag ttgttcgatg attgatacct gagacattga
    16381 tcggtacagc aatactgtca ccgatcgatg caagcaaatc gctagagccg cttacttctg
    16441 cttccagttt tgaaaaactg aaatcatagc tttctacccc ggcagctggt gttccttgct
    16501 gtatcccata aagtcgtacc gacttgcttg gcttgatcga atcagctctc actgttactt
    16561 gcactggatc agagacgata cttaatactt cccctgctgc attcagcgcc tgtattggga
    16621 cctcactatt aatcccatca tctgtgacca tcgaagcgtc cacatcagct actactcgtt
    16681 tgatttctgc caatgttttg tcacctgtag tgatagagac ttttttagga ctaacggaag
    16741 tatcatcaag ttcatatcca gatggtgtga acgttgaagg aatcaacgtt tccacatcga
    16801 aatcttttat tacctttttc tcaaccgtta ctgtaatagt cgatggttcg atctttgctg
    16861 tgacagcact gctcaaattt tgaattttta gcggaacttc atgtgttcct tcgcccagct
    16921 tagtgatatc tgctgtgacg cggaacatcc gtgtatcttc gtttgcctct gcattcaact
    16981 gaactcggtt tgcactggaa agtttgacag tcactgcatt ttcatatcca tggatatagt
    17041 agcgctttga atcataagaa atcttgatcg gcacccccgt aactgtttga ttatacgctt
    17101 catttccaga aagcgtattt ggaacggact ggccatttgc attgaagtac agcgcaatac
    17161 tgaacagcaa tgcaataaaa ctgtaaagaa tgcttgtccg tttctctttt gagatcattt
    17221 gcgatcccct cccttagtca taccgtctag gaaagattga atcacgtttt tcttgttttt
    17281 tgttttctct tcagcaatta gttctctacg caagattgcc aaatattctt gctgggataa
    17341 gccagccatc agttcattat ctaacgtgat gctgacgtcc ccggtttctt cagagacaac
    17401 gatggtaatc gcgtcactga cttcgcttat accgacagct gcccggtgtc gagtcccgaa
    17461 ttctttaggg atcaacatac tttctgatag aggaagatag gcgcttgcta ctgcgatctt
    17521 tccttctttt acaataactg caccgtcatg cagcggtgta ttaggaataa agatattgat
    17581 cagcagctcc ccagtgatat ctgcatctaa agcaatccct gtctcaatat actcatctaa
    17641 tccagtatga cgttcgatag tgatcaacgc accgattttt cgcttggaca tatattggat
    17701 ggctttgtca aaagacaaga tcatcttctc atcttcctgc tgttcgcttt ttgattgttt
    17761 gaaaagcgaa ctgcgtccaa gatgttccag tcctctccgg atttccggct gaaaaatcac
    17821 gatagcagct atcaccccgt acgtaatgac ttggttcatc agccaagaca aggtgtgcag
    17881 accaatgatt tccgctacga ttcggataac aataaaaata gctacacctt tcagaagctg
    17941 aatcgctttt gtgcctcgca gcagttggat cagtttgtat acaagatacc agacaaccag
    18001 aatatcaagt atgttcacca aaaaattcag agagaacaag tcaccggaaa acatttgctg
    18061 ccaatagtcc aaattaaaaa gttccccgat ttgaaatgac ataaaaagcc tctcttctct
    18121 tttgagattt cctctctagt atatcatatg ttttaatttt agaggctgat atgctcgtat
    18181 ttttcttgag aaaaacgcat aattttcaag aaaattgcaa gtatgcgttt tatttttctc
    18241 tgcaataaat atttttaaac ttcagagaat tattcattat attttttctg ttatttttcc
    18301 tttttttctt ttgtagcttg ttccattttt ttacgtcgtt ctgctctggc agctcttcta
    18361 gcagctcttc tttcttctgc ttcaaggtcc gtcgtttttt cttttctagt cttaacgggt
    18421 acatcgatag attcctctgg ttcaagtcgt ttcttgattt tttctaattc tcccgtcagt
    18481 gcagcatagt tgtaaaaacg tgttttagcg tcgtggacag tcttttcaaa taaagctttt
    18541 gcaagatttg gatttgcgtt atctagcgag gaaaagcgaa cttgtttcct catgaaatca
    18601 ggcatagcag agaaatcagg ttttttgtag tccaaagtca ttgggttctt gtttttttcg
    18661 accattgtag ggttatatcg atataatgac caataaccag aagaaacagc ttcttttgct
    18721 tctttaagcg attctttcat tccgccaagc aagccatgtg tgatacaagg cgtataggca
    18781 ataatcagag aaggaccagg atacttttct gcttcttcaa atgccttgat cgtttgcatt
    18841 tgattggcac ctgaagcaat ttgcgccaca taaacatttc catatgtcat cgccatcatt
    18901 cctagatctt tctttgaagc atactttcca ctagccgaaa atttagcgat tgccgaagct
    18961 ggtgttgctt ttgaggtttg accgccagta ttggaataga cttcgttatc caaaacaagg
    19021 atattcacgt ctgctccgct ggcaagtaca tgatcgatcc cgccaaaacc aatgtcgtaa
    19081 gcccatccgt ctccaccaat catccattgg ctgtttttta cgaatagatc ctttctcttg
    19141 tatatatcct ccagttcagg gaaaattgat cgttcgcttt cgatcgcagc ttgcagtttt
    19201 gctgctcttt gctgcgttcc ttcactctca aacatgtgta ctaaccagtc ttccatcaat
    19261 tctcgtagtt cttctgatac ttttggcaat acttctttga ttgaacttgc caaagcctcg
    19321 cgacgagtct gtgccgctag aagcatacca taaccaaatt cagcattatc ttccaataaa
    19381 gaatttgacc atgcaggccc ttgaccacat tcattggtcg tataaggaga agcaggagaa
    19441 gcaccgcccc aaatagaaga acagcctgtc gcattcgcga tcatcattcg atcaccgaac
    19501 atttgtgtca ataattttac ataaggtgtt tcgccacagc ctgagcaagc gcccgagaat
    19561 tcaagaagcg gttgattgaa ttgtgtagac aagacagtat tctttccttt gactggattt
    19621 gctttttgtc ttaatgtcat tgcaaaagcc caattcacag cttgttcttt ctgttcttca
    19681 taaggcttca tcactaaagc tttttctttt gcgggacaag cctctacaca cagaccacaa
    19741 cctgtacagt cttccactga aacttggata cggtatttta cgccgtctgc gcctcgcatt
    19801 tctctcacga taaatccttc tggcgcttct tccatttcct cttcatctgc taaaaatgga
    19861 cggatggcag catgaggaca aacaaaggca cattcattac acatcgtaca gcgatcacta
    19921 atccactcag gtacttctaa agcgacgccc cgcttttcca tagaagccgt tcctaaaggc
    19981 atttcgccag ttgtcattcc atttgctaca agtgtaccaa cagagagttg atttccttcc
    20041 tgtgcattca ctggttcaag tatttcttgt atataaccag tgttcctttt attgattttt
    20101 tcaggcatct ccaacgttct ccaatggtct gggatcgcga cttgatgaag cagttcggtc
    20161 gtccgatcga ttgcttgtat gtttttttct acgatagcca ttgatttatg tccatagctt
    20221 ttcagggctt cttcttttag cagcggaagc acctcatcaa aaggaatgat gtcagctaat
    20281 ttaaaaaaag ccgtttccat tgccgtattg atccggcgtc ccaaaccgac ttcttgggcc
    20341 aatctcatgg cattgatcgt atagaatcta atgttatttt cagccaagta acgttttaat
    20401 tttaagggca gatgcgtttc taattgttcg tcgctccaaa gagtattcaa taaaaaaatg
    20461 ccacctggct tcaatccttt gaccaagtca tagctatgca ggtaagctgg tgtgtgacag
    20521 gcaacaaggt ccgcatgctc gacaagatac gctgaacgta tcggcgtatc tccaaaacga
    20581 agatgagaga cagtcagacc gccagatttt ttcgaatcat aataaaaata gccttgcgca
    20641 tatttatcgg tgtgatctcc aataatcttg atagctgatt tatttgctcc aactgttccg
    20701 tcagatccaa atccccaaaa cttggcctgg aatgtttgcg gttctgtcaa atccagactt
    20761 tcctttggtt ccaaagattg ataagtcaca tcatccacga tccctatggt aaaccgtttt
    20821 ttgcgtatgc ttgggtcttt tttcaattca tcaaaaactg ctgagatttg gtcgggagtc
    20881 acatctttag accccaatcc gtagcgacca ccaataacag ccgggcgaag ttcagaatca
    20941 tataacgcac tttgaacgtc taataagaga ggttctccac ctgcccctgg ttctttactt
    21001 cgatcaagaa cagcaattgt ttttactgta tgaggcaact tttgcacgaa tgtttccact
    21061 ggaaaaggac gataaagatg gatattcaaa aaacctgttt tccgtccgtt tgcattcaag
    21121 taatcaatcg tttgttcaat cgtctgtgca actgatccca tagaaacaat gacttcttcc
    21181 gcatcgtctg ctccgtaata agtcaccaag tcataagaag ttcctcgtaa tcggttgatc
    21241 tctttcatat atttttgaac gatttcaggt aatttatcat aataggggtt gatcgtttcc
    21301 cgttgttgaa aatggatgtc tggattctgg ttcgtaccac taacagtcgg atgattggga
    21361 ttcatccctc gtttacgaaa tgaagctaat ttctcctgat tgatcagagg agctaattct
    21421 tcatattcca aaacttcgat tttttgaatc tcgtgactcg tacggaatcc atcaaagaaa
    21481 ttcaaaaaag ggacttctcc ttcaatagaa gcaagatggg caacaggtgc taaatccatc
    21541 acttcttgta cactgctttc agctaacata gcaaatcctg tttgtcttgc agccatcacg
    21601 tctccgtgat ctccgaaaat attcaacgca tttgtcgtca ctgcccgact agcaacgtgg
    21661 aaaacacttg gcagtagttc cccagcaatc ttgtacatat tcggtatcat caaaagcagc
    21721 ccttgtgaag cggtatatgt agttgtcagt gcaccagttt tcaatgatcc atggaccaca
    21781 ccagctgctc ctgcttcgga ttgcatttct actactttta ctggttgacc gaatacgttt
    21841 tcttttcctg ctgctgacca ttgatctact aattcagcca tggtcgaact gggtgttatt
    21901 ggatatattg cagcaatctc ggtaaatgca taagaaatat atgcggctgc cgtattgcca
    21961 tccattgttt tcatttttcg catgattcat catccttgtt catattctct cttattatct
    22021 gttccattat aacgtaaaac atgccatttt tttcttttat ttataaaaat attttacatg
    22081 tatctatttg aattggtcat ctaattttta gacaaacagt ctaaatcgtt gccttttttt
    22141 gtcagacatg tataaactat aagcgaaaga ggtgttttaa catggatata tcagtgattg
    22201 atgcaacgaa aacaaataca caaaaaggaa tcctttatgg ttcatcgaat gctcctaaaa
    22261 aaatggtcga attcatcaac ttagcttgtc cgtattgccg acaatggttt gaagaatctt
    22321 atgagctatt agaagaagca gtccaaagcg ggcaattgca gcgagtgatc aaattgttcg
    22381 ataaagaaaa agaaagctta cagcgaggga acgtgatgca ccggtatctc acaatcagcg
    22441 atggccaaaa agcgatcaaa gagatcaaac aaatattcga tactcaagac gagtggaaac
    22501 atctttctct ccaagaagta gcggattttg cagtagataa actaaagctg acagaacaaa
    22561 aagacgaaca gctgagccaa gctgtcatca acgaagctga gcaagcacat attcgatttg
    22621 ttccaactgt catcttgggt aaagaaatct ttgatgaatc tatttcaata gaggaattaa
    22681 aagaattgat ccaaacaaaa taaaaaaata aggagcgtg
//
LOCUS       DADLIO010000046        22172 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.046, whole genome shotgun sequence.
ACCESSION   DADLIO010000046 DADLIO010000000
VERSION     DADLIO010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22172)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22172)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22172
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.046"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(<1..331)
                     /locus_tag="JOX41_001851"
     CDS             complement(<1..331)
                     /locus_tag="JOX41_001851"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449594.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            complement(345..575)
                     /locus_tag="JOX41_001852"
     CDS             complement(345..575)
                     /locus_tag="JOX41_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449595.1"
                     /translation="MCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQKGYPYGPTN
                     LKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            complement(797..1339)
                     /locus_tag="JOX41_001853"
     CDS             complement(797..1339)
                     /locus_tag="JOX41_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449596.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VDQEAQKIDAIKIYYVRSAY"
     gene            complement(1360..2451)
                     /locus_tag="JOX41_001854"
     CDS             complement(1360..2451)
                     /locus_tag="JOX41_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HAY6449597.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            complement(2459..4669)
                     /locus_tag="JOX41_001855"
     CDS             complement(2459..4669)
                     /locus_tag="JOX41_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449598.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            complement(4685..7213)
                     /locus_tag="JOX41_001856"
     CDS             complement(4685..7213)
                     /locus_tag="JOX41_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAY6449599.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            complement(7265..7675)
                     /locus_tag="JOX41_001857"
     CDS             complement(7265..7675)
                     /locus_tag="JOX41_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449600.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFYIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYMI
                     RMMNGDCVYYNWDKVSNNALEELLFVNKYVYLED"
     gene            complement(7688..7906)
                     /locus_tag="JOX41_001858"
     CDS             complement(7688..7906)
                     /locus_tag="JOX41_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449601.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            complement(7903..8895)
                     /locus_tag="JOX41_001859"
     CDS             complement(7903..8895)
                     /locus_tag="JOX41_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAY6449602.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVITKKTNQYYVEKLTHNWLDRKGEERK"
     gene            complement(8974..9885)
                     /locus_tag="JOX41_001860"
     CDS             complement(8974..9885)
                     /locus_tag="JOX41_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAY6449603.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            complement(9904..10248)
                     /locus_tag="JOX41_001861"
     CDS             complement(9904..10248)
                     /locus_tag="JOX41_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449604.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            complement(10268..10824)
                     /locus_tag="JOX41_001862"
                     /pseudo
     CDS             complement(10268..10824)
                     /locus_tag="JOX41_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(10905..11405)
                     /locus_tag="JOX41_001863"
     CDS             complement(10905..11405)
                     /locus_tag="JOX41_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449605.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            complement(11406..11951)
                     /locus_tag="JOX41_001864"
     CDS             complement(11406..11951)
                     /locus_tag="JOX41_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449606.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            complement(11948..13204)
                     /locus_tag="JOX41_001865"
     CDS             complement(11948..13204)
                     /locus_tag="JOX41_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAY6449607.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            complement(13565..13876)
                     /locus_tag="JOX41_001866"
     CDS             complement(13565..13876)
                     /locus_tag="JOX41_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449608.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            complement(13899..15209)
                     /locus_tag="JOX41_001867"
     CDS             complement(13899..15209)
                     /locus_tag="JOX41_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HAY6449609.1"
                     /translation="MYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLV
                     RMLIDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGH
                     LLSEVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPN
                     MLIAGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEE
                     MIICLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDME
                     ARNRVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYL
                     MTFGEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYD
                     FTVKEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            complement(15823..16275)
                     /locus_tag="JOX41_001868"
     CDS             complement(15823..16275)
                     /locus_tag="JOX41_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449610.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            complement(16277..16642)
                     /locus_tag="JOX41_001869"
     CDS             complement(16277..16642)
                     /locus_tag="JOX41_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449611.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            complement(16741..21024)
                     /locus_tag="JOX41_001870"
     CDS             complement(16741..21024)
                     /locus_tag="JOX41_001870"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019941.1,HMM:NF037291.1,HMM:NF037639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HAY6449612.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            complement(21171..21410)
                     /locus_tag="JOX41_001871"
     CDS             complement(21171..21410)
                     /locus_tag="JOX41_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449613.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            complement(21500..21772)
                     /locus_tag="JOX41_001872"
     CDS             complement(21500..21772)
                     /locus_tag="JOX41_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449614.1"
                     /translation="MSDGFEQVSIIKNQVREILRKKGYLVDSYFEGDYETWVGVYARP
                     ENKPTYLDPTTSEDAYLQNRYRVDGFKQDFAEWFEWEIENGEVKEE"
     gene            complement(21855..22106)
                     /locus_tag="JOX41_001873"
     CDS             complement(21855..22106)
                     /locus_tag="JOX41_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449615.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
BASE COUNT         6479 a         4804 c         3308 g         7581 t
ORIGIN      
        1 atgaattcat tccccaaagg ccttttaaga ttgatacagc agtccgttca cttcttttag
       61 acttgtcata caagtctttt aaatgatccc atatcagact agtttgtcta tctagcttca
      121 atccattaaa cgctaatgaa cggttcattt tttctattac tttagataaa gctacagaaa
      181 tttttatacc ttcacaacgc gcatcttgga tttcaataat agtatcatca attagttttt
      241 gaatttcttg cctatcaaca tattcaatct tagaaagaga atcttttaaa gctactaatg
      301 attcaacgat ttcttttttc tcttcagaca ttttcttcct ccttctagtg acccgtaaag
      361 ccatgtagag cagagtccat tgaaccagta attacactat ctacaacgcc attccaattt
      421 actctacatt ttccattttt cagatttgtc ggtccatacg gatagccttt ttgacattca
      481 atgttcggat tataccagat aggattatac cattcagccg cagaagcaga ttcagtcgat
      541 acaaacaatc ccacaccaac aaatccaata cacatcacac tatagccaat tagttttttc
      601 atctcgtatc catctcctaa aaaatagaat agttcttata gttattcata agacatattt
      661 tttccgtttt tgttttatcc tttctgtcct ataacaactt ttttcaagta aagaatgaca
      721 tagtttttct taaaaaaaca gtctgttttt ttctatttct tcggtgtata ataaatatga
      781 gtgttcattt tttattttaa tacgcactcc gtacataata aatcttgatc gcatcaatct
      841 tttgagcttc ttgatctact ttcaattgaa gtaatacaaa ttgagtaacc ttattcattg
      901 tttcttctcc aaataacaaa tattgatccg gattctctat atcttgtgtc acctggtaaa
      961 gtttcccagt tgttttcatt tgtacatgcg ggtctacatc aatactattg tctttaatac
     1021 aacgatctgt catatagtcc ctcacagctt gattgcgttt ataaacatct gtgaaattac
     1081 tccattttct agcaaaatct tttaagaaat tttttgtcat ttcatctatt tgcatttgtt
     1141 gcgctgtctc gtcttctaat gaaccaattt gactgttact ttcagtactt tgaagagttc
     1201 cacttgtttc ttttactgct tcgattgttt cttctgtcgt tctcaattgt gttttttgtt
     1261 tttcagaaga aaaccaatga caaccagtaa gacctatcaa acataaccaa ctaaatacta
     1321 aaattatccc ttttttcacg tttctagtca ctgcctttct tatttcacct tacgaaccag
     1381 actacgaatt tttgtttgat tgtacgtgcg ttgataccga gccataatcc gtccttgctc
     1441 ggcattctgt tccacactag agaaatgttg tccgccatat gaaacatctg ttataattcc
     1501 ggtgtgacca tagattccag gagacaatgc accacctgct tgccaattca ccacatctcc
     1561 tgcttgtaaa tcacttggtt ttgggttcat gattacttgc caaccatagg ttgtccagtt
     1621 ataatcttcc cctattaaca tcgcaaacat gtgtccagaa cccattaact gtgggccacc
     1681 taattgagat acataccatg ccgtaccacc ataacattcc ccattattta cggatcgtcc
     1741 aatgatccga tccaaaacct tcgcattgcc tttacttttt cctgcaataa gcgaagtttt
     1801 ttttgttggt aggctattcc aatgcttgat cgcaaaagta tcatattccg ttaagttata
     1861 ggacgttatg atactcattg ctcctcgata atacggactc ccttcggtaa tacctgctgc
     1921 cgcatagcct ccacgaccta gaatcaataa acaacttcca ggatctttat tgcccacaca
     1981 ttgattaaag ttgctttggc tcgccaccat aaagccataa tagtcataac aagcttttaa
     2041 gttcggaaac ttcatataga aaccaccttc agaaccacca attccacgtg cagaaccttg
     2101 tgggtaggga caaccaggaa accaggtaat cccaaaaaag ttcgtatcgt ttcttccaga
     2161 ttgtgactgt ccataagctg attcatagcc taattgagaa agaatcacac tcggtaataa
     2221 ctgatacttt acagctgcac caactgctgc ttgcgcatgt tcatctgtga ttggaccacg
     2281 tcctttaatc tctgaaaaaa tcggtaatcc ttcggtatat tccccattaa aagcgacagc
     2341 tagacctgta gcttctcctc catgctcaga aagttctcct gaaaaaaaga atggcaatag
     2401 aaaaaaggga agaataaaga aaagaagaca acctagacac cctttcttca tttcttcctc
     2461 atcctttctt cgataatggt ttttggactg ttcgtccttt tggtaaagta aaatcagttc
     2521 ctggttttgc gtccaaaatc ggcagtgttt taggatcctt ttctattttt tccgattgct
     2581 ctgttggctt atctaaagaa gaaaatgcag gttgtaacga ttttggtgcg gaaatcgacg
     2641 gtttactttc agacgaacgt tgccccggtt gttgcacaga acgatttcct gatagagtgg
     2701 ctaccgacga attaggaaca gagtattggt tcaataactg ctgcattgct ggataactcc
     2761 catttttcgc ctgatttttc acttggcgaa tctgttgtga aagagaacca gcagctgtta
     2821 attgtggcac gggtactttt ccagaaggca acggaatcga ttgaccaaca aaagcgatac
     2881 ctttatttaa caatggtttt ctttgattat tcccttgttg cttactcaat tgtgccaatg
     2941 attgtacctg ttgttttggt cttactgaat tcatggacga atttggaatc aaaccatttg
     3001 aaagaccaga attccactct gttttcgatt tggtagaaga catttcaggc tctaccccat
     3061 gataacgaac atgacgacca ctataaggca aggcttgatt tgaacgccca cctagttcaa
     3121 agggattaac cacttgcctc ccttttaccg attcttgtgg tgtacgtttt tgttgaaact
     3181 tttgaaatcc atgtatcgct gcagaagcga gtggattcgt tgctcgatac acattccctg
     3241 ctaatcctgc acctttgatt gccaaatttt gtccagcagt tgatagttga ccaggcagtt
     3301 gtttcatttg agacaaagaa tgacttgcta tgtttttcgt gttgtttata gtttgatctg
     3361 cagctcctaa ccctagtttc tttaataaat ctttccgttt tacaatgagt aaaattgata
     3421 ggagtgcttt gacaaacata tttcctaaaa aaccaaaaac agtattcatt ggaattaaat
     3481 cgtctactat gttatagatc aaaaatgcca ccaaaataat cacactgtaa aaagattttt
     3541 gaaacatcaa gcccaaaaag gactttaagg tattcatgag catataatca aatactggaa
     3601 caaaagaagc gagtaatgaa aaaggaatca caagtaataa acacaacacc aacatttgaa
     3661 agataaaacg aatcatgcca atcactacaa gtggtaatcc aatacttaga ttaagcaatg
     3721 gcaccataga accaacgact gctttataaa cagctttagt tggttgaata tagacacgat
     3781 aagccttctt tttccctcta tcttctcctg cagcagtggt cacttttgtc tcaatatcag
     3841 ataattcttc acttgacgct tccttggcta gaaattcttg tggttcaatc tctgcttgat
     3901 acaattcttc taaatttgtt gtcccataat ttaacaatat atacggatca acaacagccg
     3961 ctttataata aagttggcgc actttttgaa tggcttcctt ttgtgtcgtt ggcactaaaa
     4021 caccattgac atcttttgtc gccaattcat ctagactatt tgtagcagaa aaaataaagc
     4081 cttctacctc cacggacaaa tcatttaacc ctttggtaaa agcttctcct ttactaggta
     4141 cgttactacc atagccaaac caaaccattg aaaaaatgac aacgaagaga aatcgaataa
     4201 acaccatttt tgcgtaatgt ttccctctaa atatacgaag agtaaataga tataacacat
     4261 acaagacgac aatccccgca ccaataggat cgtatatttt tgaataaata gtatccgaaa
     4321 aagtgaaaaa ctggtgaatt aactcgttca ttgcagctcc ttcatagagc ttctcaatga
     4381 caaaatcaag gccttgccaa atcaatttac ttaaactaaa gaacatattc gtcatcattt
     4441 ttagaaaatc tgtgccattt gccccaaata acattttgcc taatgaaaat tcactatcag
     4501 ataaataaga agaaaaggta tcaatatgaa atttcccaat ctcatagatc gattgatcca
     4561 cctgcttttc tgccgcatac accaatccac caacaaaaag cagtccgaat ccaatcgtta
     4621 aaaaaaacaa aacgcaccat ttcttttcct tatgctttat ataagccatt gtttcacctc
     4681 atttctattg catgattaac gtatcctgtt cttctacttg agagtgactt gttttttccg
     4741 ttgtttgtaa tgcagcggtc atttcttcaa acaaactgtg tacattgagt tttcctacac
     4801 gtccataggg atctaacatc caacactgtc ctttaatcat gtggctcatt tcagctaagt
     4861 tcgcttcatt tacttccaaa cgtaaatgat tcaaaatctt ttctcgctca ctgtcttcat
     4921 caaaagcaaa gacgacacca aaattccctt tttctttatc tgaacctaag tcaccaataa
     4981 attgtgtatc taacactaat tgattcatct gggaacgccc cacacgtgcc attgctgcaa
     5041 taatactacg tcctgcgttc gaattattaa atacccatgc ttctgtaaaa taaatcgctg
     5101 ttttcttact actatctcgt tttccaaaca tttcacaaaa acgacctaaa ctaatcatca
     5161 aacacaaaga ctttcgatcc gcatctgtat atagttctgg tcggacattg tcatttggta
     5221 atttcaaatc ttggatctct aaaatcgttg ttttggcatt aaagtctaat cccgggtttt
     5281 ctccataaga aaatcctaaa cgtaaaatcg aatcttctac cgtcaagcgt aaaaactcac
     5341 catattctcg aacctctttt tgttccattt gttctaaata gtcgaccaca tgcatcaagc
     5401 caacttgttg tccggcttct ttttgaacta aaacttcttg gattcccttt aataccgccc
     5461 cttttaaaag gtgattggta cctaacggac ttaactcatc aatcatatcc tgggctactt
     5521 gtttcgcatc tactcgggat aaacaaacaa ttggatctaa tacaccataa ttacggggat
     5581 ttgtagcatc taacgtgaca taactcattt tttgcaaatg ttctacaaac aaagggtaat
     5641 gtttctgata atacgggtct tgaatgagtt tcgtaaacca tttgcgcttt tctcctttgg
     5701 gatccacaaa taaactttgt acattcataa acgaactata caaaaagagc aagccaacta
     5761 aaaaggtctt ccctttaccg gtttttccag ttactgctac atgaggcgca tcaaacaacg
     5821 cacctttgat tccttccgca atggctagaa gattcaaaaa gacaaaacga tttgacgcat
     5881 aaattaattc ttctaatggt gttttttctc ctcgagaacc accatcccct aatgtatctt
     5941 gccgaccaat ataccagccg gattccatac ctaattctga tactgctgaa aacaaccatt
     6001 cgccaactgc ttctacagtt gttcggtgct tccaatgtaa ctgccgtccc aatggttgcc
     6061 ctaataaaca tttatagaac aattctcgtt gatcattttt tgcacggtgg atatggataa
     6121 tcgtatgaag ttgttgaata accgttgcac tattttgacg aacttcttca accgtttgac
     6181 cgtatacaat aaaacatgcg atccaatcga cgacaggttg cccattatct actcgttgct
     6241 ttaaatgttt tactaatcct cgaacagtta ataagcgttc actaggttct tcatcatttt
     6301 gaaccaattc cttatgctct gttttgaacc gttccgatag ccaattcagt tttaaaccaa
     6361 tacctccctg tcctttcaag cgtggatagt gaattttcat tcgcaattct gctgggaaag
     6421 aaagatcctg agcaaattga aatagatcac aatttctcat attttcaggt gtttccccaa
     6481 taggcaacaa tgctaaataa ctactcccta actcatcttc taattgaaga aggcctttat
     6541 gttccttcgg tatacgtaca tacgttcctt gattgtcttt cagtacttcc caattatttt
     6601 gttcttctac tttgtgagcc attcctcgaa tatattgcag acgattgaga tacaacagct
     6661 ctttttttac taagggacga atagaaaagc tataaagtaa ttgtgtcact tcttttacat
     6721 aaggatcact ttcagaaaac aaagtttcca aatcatctac ttctaatcca aataagcgtg
     6781 ctaaacttcc tgctaaatct aaccagatta gatttattac atcatgaaaa ctctccaccg
     6841 ttgctttttc tttgactttg attcctaaaa taaatgaagg acgatagact tgaccttctc
     6901 gttccaacaa tgtcactgtt tcttttgcat aatacgcacc aattgcttga ctatcgggag
     6961 aaaatccctt tcctaatgtg tcaaacttcg tccgtaaatt cattgttcgt ggatacatca
     7021 ccaactccac atcttcataa tctgctaaaa gcaacagtaa acgagccatc atttctttta
     7081 tttcctgtgt cttttttggt gtgttttttg aaattgttcg tggaaaaaca tgatagtagg
     7141 cccagataca atcctctcca tttaacaaac aatttttctt gaatgctttt actggttctt
     7201 ttacaagcac caatgaattt cacctcccaa taaaaaagga acaaccagtt gattgtccct
     7261 ttttctaatc ctctaaataa acatacttat tcacaaaaag taattcttcc aatgcattgt
     7321 ttgatacctt gtcccagtta taatacacac aatcaccatt catcatacga atcatataac
     7381 aaaaccaatc ccataaataa aaatgcactt tttttccatc aggttttagt tttgccagtg
     7441 ctaacacaca taaatagggg agtcctatat aaaaaacaac tcctgctggt ggaaaaaaag
     7501 aaatgaccca accaataaat gaacgtaaaa ataaatattc aaagattacg accaacaaaa
     7561 aagttgctgc attgactaat gcaactggaa atggaagacg ccaattgctt gtaatctgtt
     7621 gtacgcgata aggttccgca taaacaatcg aataatcata aggttcccaa tccacttcac
     7681 tatcctccta atccataaat aatttttcaa tgattttacc aaacgcatca aatacacgtg
     7741 ttggatcatt taagaagaaa taaactgcgg cacctgctgc gatagatatt aatgcatttc
     7801 ctacttttga tttcataaaa tttcgcaatc ccagataaac aaccaccatt attaaaaaat
     7861 agccaccttg cgttaatata aaatctacaa ttcccttcag tgtcatttcc gttcttctcc
     7921 tttcctatcc aaccaattat gtgttaattt ttcaacataa tactgatttg tttttttcgt
     7981 aatgacaatc gtcatttgtt ctttttgtaa aagtgacgta tcaccatctc gaaagacgac
     8041 cgttgctttt acaataaaag gttttttcgt ttctttataa cgcaatactt tcatctctac
     8101 ttgatcaact ttagctgttt gattgagtcc ttcaggttct ttcatcatgt atgacatatc
     8161 ttttgcattg tttttcgcat acttatctaa gaaatcttcc acaaatcctt caacatcttt
     8221 cgcttccgac gcatcaaccg tttcgtataa tgtgtcatca taagtaatca ttcgttgttt
     8281 ttctgtattc tttggtagtg ccgtaaaata aggataagca ataatacgac agcccttgtt
     8341 tgaaatagaa aagggaagat tgagtacttg tgtgattgtc acacttgttt ctttcttact
     8401 ctctggattc atcgagcgaa tatcataagt tactttataa ctagcagttg gaatggtttc
     8461 aatttctttt aatccaataa acgaagcagc agttaatttt cgaacacctg aaacacttcc
     8521 tggttcttga ataaagtttt gtgcataaaa ctcttttttt aatgtttctt gacgttgttg
     8581 ttcttgttca tgattatcga atgtattcat atacaaagca acaaaacgat tcataaagga
     8641 ttcaatttca ggtgtgtacg ttaattctga ccgactttgt acttctttct tttgtaattg
     8701 ttggatttca tctttcaaaa acgacacttg aaccttcgtt ttcatggatt gaaaaaatgc
     8761 caagccccct gaaaaacaaa gaaataaaac caaacaccaa atccatttca ctgctttttt
     8821 tgaatggatt ttcttttgct tcggtacttt ctctgtataa actttttctt tccgccgtag
     8881 ttgtcgtttt ttcataagct actccttcta gtatgttttt actagtacgt acgattgaca
     8941 acgataagct tgtttttctg aaaaatagtc cattcaatta ccctcatttt ctattccttt
     9001 tctctttctt ttatatccaa caaatccagc aatacttgtc aacactcctc ctagaacaga
     9061 aagtgcaaca tgtatttctt caccagtctt tggtaagact tttgtttttc catctgctgt
     9121 tttgatttca atattgccac ttggaagttt ctttacagga atcgacaaat cctttaccaa
     9181 attcccttca ctatcttgga ttaatggaat accatctttt acaccaacaa ttgtttgatc
     9241 acctgctact tttaatgggg tggttggtgt tggaatatgg gtcaattcct ctacattact
     9301 agtgacaatc ggtacactca ttccttgaga agtattcgtc gtaatttcac cgcttggggt
     9361 taccgatact gtgacttctt ttgctggaac aataggttta ttttcttttg gaattgcttc
     9421 tgatttttca acaggttgtt tcggttcttc tttttgttct tcactggtag acgacatcgt
     9481 tggctgttcc gtacttgacg aatcagtatt cttttcagaa gaactggttg ttcctgattg
     9541 ttccggagtt gtgactatac ttgaatccgt tgttgttgaa ctatgcacac cttcttcttc
     9601 gatcgaatca gtcggtaaag ttgattcagg aaactctggt tctggtgtca ctggctcttt
     9661 ttcaggtttc tctgactgca attgttcagg ttctgctggt ttttccgttg ttcctccatt
     9721 tagctctgtc tcaacatctg gtaatccttc ccctggcaat gtttctacaa tttctgactt
     9781 aggtgtttct acagtttcat ctgcataaac caatgaactc cctaattgaa acgaaaataa
     9841 tgaaattcct agtgttgtta cgactgctaa tgttgttttt ttcatgatta ttcctccaat
     9901 tttttatgca attcgtgttt tgttcataga cgccgcacta atattatctg aacgataaaa
     9961 gaactcccgt ccgttttctt ctaacccaac atatggatta tttttgaata attgaatcaa
    10021 tagttcactg gtgttgtatt ttggatagtt tgcaaaaaaa taatactgtg cttgtcgccc
    10081 atccgaaaat tcaacaagta attcataacg ataccgcttc aatccttttc gttgttttaa
    10141 aggatctcta taccaacttg tccatcgttc cattcgtgga tagagataga cacgatacac
    10201 atagaacaat gccataccac ataccaccaa aaataataat cgccacataa aaattccccc
    10261 ttttcttcta cctttcttga atcatcgaac attcataccc tctatagaga tttgaaaaat
    10321 ccatcatcaa ttgttcatat aaacgttgtt gcaaatagcg attgtttcga atacataatt
    10381 cttcatagcc atcaatcact tgatcttctt tttcatagca tcttgtagct ctatgacgct
    10441 cagcttgcat gacataacca aactctgcac catatcgttc tactgttaat aactgttgac
    10501 tacgcaataa tgcaatataa caatcacaaa aatgttcaac cgacatttga tttttctcac
    10561 gtttgtgaaa taggtattct ttagaaagca cattattcgt taaacaatct gataaatagc
    10621 gataatctgg cggtcggtta ttttcatctg tgaatttttc ccataataaa ctgattttta
    10681 ttcgttcagc ggctagatag tcttgttcgc gtggataaaa ttcatcaatc gcacaaagtt
    10741 ttttatcacc tgaataaaca aatccatata atgcgaaacg aactcttcct tttcaattgg
    10801 ctctcctaaa aattccagtg acataccatc ttctccttcc taaaaaaaat aaaaaagcag
    10861 aaaccgattt ggcttctact tttctttcct tttatagctc ttttttacgg aagaatccgc
    10921 aaatgacatt ttttcaaaaa atcaatcggc acaagttcac gaaaacttgg agcaattttg
    10981 gatagaatca cttccccatc ttgtaaaata caatcataaa aatcatcagt tacttgatac
    11041 ttacgcttct tacaataatt gataaaatag tagcgatcat tttctatttc cattcgttgt
    11101 tctactaagc gcatacgaac atcatcatag aaataagcca caaatcgccc ttcaagttca
    11161 tgtttttcaa tgggatactc ttctggtaac aatctatttt ttcgtcgttt atacattgct
    11221 ggatacctta gaagaagttc atctaaacgt ctgtcagtat atggtaactg acgaatcaac
    11281 gattctaatc gttctttata cagatagaat aattggcgca agcaatagtg taccgcctct
    11341 ggattttcta atactgttgg atcacgtgac caatacgcac caacataaat cataattttt
    11401 ttcatttaga caatcacacc agcaatacta atgaccgatc cacaataggt agaacaagtg
    11461 gcatagcgac caatttcctc taattctatc tcaatctctt ctaaagaaag atatgtctgt
    11521 tcttctgttg gctggcgact catttcccaa gtgacagtca ccaatgaaat ttcttccata
    11581 agaggttttt cgctgctaag tgctgccaca cagttttcat atatcttcat tttatcgcag
    11641 ccttttttaa ccgctaaaat cgcaggtatt ggcaatgaaa atcgataaaa gcgaatgaat
    11701 tctagccttc ctttccttcg gctaaattcc aactcttcga gttcttgttc gtatccctta
    11761 cgaacttcta ataagcgtgc aatttcttgc cagttctctt tttcctgata acgtccagct
    11821 tttaccgctt gttcaatata aggaactcga aaacgaaaat aagacaaatc aaccatcttt
    11881 tcatttaatg cttcgattgc agcctttaaa tccaacaggc gcagccattc tgttgtcgta
    11941 tatgcattca tgcaattttc cctcctgacg ttcccatcca ttctagatag ttttgttgct
    12001 cgtcatttag ttcggcatta tcaatccctt cttgtacaaa gtctcttcct aaaatacgat
    12061 ctgcttcttg taacaacttt aatgtcggag ctacttgttt caaaaaccag cgttctgaac
    12121 gatctaatga gaatttttct ggctttactg taaaatccaa ttcttccatc gaacgaaata
    12181 attttgccca tcgtttatca acaatccgtg catcactttc cagtctatcc caaacaataa
    12241 gttttgcatt aattaaacca acgccaatct ctcctaaacg tttcggtgaa tcacctaaaa
    12301 taaatgcttc tactgcttgt gttgctttct cattggctaa ccgtaactca tatcgattat
    12361 aaataccata tttcgttaat gcttctaatt ctgaaatttt ttctcggttc gcaatttcaa
    12421 aacgtttctc ataaaaatta aaaaagagag gactctttcg cgatccaaaa tacaaagata
    12481 atccttcact tcgaaaatag ccatcatcta aaaaacaacc gccaatattc tggaatctct
    12541 taaagtccat ttctaataaa cctgcttttt gtttttctag taattcaaag agatcgaaat
    12601 gttcttccgt ttccaatccc caaagttcat ctaacgcaat atcgaatcgg ctacattgca
    12661 cacgtgtata accagcttcc aactttcctt gatttttcca aatggaatat agccatgttc
    12721 gccaatctgt ttgttgttca cgcatgactt cctcatattc ccggcaacct tgtcctgaaa
    12781 attgcacaag tacattttct gttacagttc gttttgaatg ccagaacacc cagatattcc
    12841 cacgaacaga aagacagtca aaaagataca agcccgttgg acgtgtttca aattctgtca
    12901 gatccattcg taatacacgt tgaatcactg ttttgtagtc tgtcccaaaa aaggaaagac
    12961 gcaaataatc aatcattgct cgaagatcta ttccgctttt catatacaat cgaaagcgtt
    13021 ccttgattcg ttgttcaaaa tcctctggga tttttctttt cccttgttcc atctttctaa
    13081 tgtaatcttt tgagcagccc atcaattgcg caaatcttgc ttgtgatagc ggctttttat
    13141 ctccacttat attatgaatt gcacttaact tctttctgta gctttttagc tcaatcggtg
    13201 tcattttctc gctcctttta taaaataaca aaatcgattt tttttaaccc tttagaaaca
    13261 ccgatatatc aactagtccc cctcgttttt tgggaaaagt agtacaactg ctgaccttag
    13321 ataatcactt gatacaaaag ggtttataaa acttttttct atgtgttatg ttatttctgc
    13381 cccccatatt atatatcggg gggctttaca caaagaggcc gtgcgcaagc gcacgacctc
    13441 tttgtgagct gcacacgctg ctagcgagtg cgcattatag gcccatgctt cgcagcctta
    13501 atgcgcaccg ccaggcagag tgcggctacc agactacgtc tagagccctc ccgatagata
    13561 ataactacaa aattaaatga tctaattttg ttatttcact atatttttca ggagaaaaaa
    13621 cgcgataaat tgacaaagtt aaatcctctt ctaaatctac tcgataatga tacaatcgag
    13681 tcaatcgttc tatatctttt ttcgttagca atacttgatt aataactttt cctgtaaaaa
    13741 cacgttcttt gcgcaaaaag cggtaatcag ttacttgttc aatacgattc aaccaatcat
    13801 aaaacgttct ggaagaaaga gaaggattaa tcattcgtat tgctgtagct actctataat
    13861 aacaactctc tgccatttaa cttcacctcc ttagttgatt acaaaatatg cgcatcagaa
    13921 aaacttgttc cttttggatc ttttgctaaa tacatttggc gctctagttg ttcttgtaac
    13981 aactgattat catctcccat cgtttgatct tgactatcct cttttactgt aaaatcatag
    14041 acaatcattt cagtaaattt ctcaaattct ttgataaagt gataatcttt gtaaacaaat
    14101 ggcgcaaaaa actctacagg tacatcaaat cctggaaaag catatccacg accaggttga
    14161 tctttgttgt aaaatggctt atttttaaaa tcttctccaa aagtcattaa ataaccaatg
    14221 ggagacaatc gaccaacaga aatacggaat gttaaattat cccgaacacc acttggaaaa
    14281 tattctgcat ctggtcgttg cattgctaaa ataatgtaca tccctgcttg acgacccttt
    14341 aatactaatg gctgaatcaa tttatcgact ctatttctcg cttccatatc caacgaacca
    14401 taaaaagctg cccattcatc aaaaaagata aaatgcggtg gtaacccata ataagcataa
    14461 tttttccctg gttcatattt aggatctttc atggttttca tataggcata ccgttgattc
    14521 atttctttta atgcatttcg taaacaaata atcatttctt catttatttt gtaaaacaca
    14581 tgtcctttga atacatcgac gtcacctaat gctgctaaat ctgccgcttt tccatcgcaa
    14641 atatctactg tcccaacact taaacaagct tgaattaaag aatacaataa ataggttttc
    14701 ccaccaccga ttgcaccagc aatcaacata tttggtgatt gatcatatac ccaatccaaa
    14761 gttttcatta aatgaatacg tccattttct gctatacatt gatcaatagg aatccgacca
    14821 gaatctgaaa ggaatacata attgattcgg gctttttctc gttcttcacg aattaaatca
    14881 cgcaaaaata cttcagataa caaatgaccc atttttaaaa atcgttcgtg aaaacgccca
    14941 ccatctaaag gaaaagaaac cactaattct tgtttctttt gataaaaata aacttttggt
    15001 aatctcattt tttcccttgt ttgtttctca ctaacttgtt tctttgtata aacaaaccga
    15061 ttgtcaatta acattcgaac aagtaactga cgccaataaa cagaggcaaa atatccttct
    15121 tttagtcgcg accaatgcat caaccctaaa attaacccac taaccagcaa caaatacaac
    15181 acaatactta ttccaggaat aagatacatt tgccaattcg aaaacgtact taaacgtgga
    15241 taaaatactt tccaactaaa ccaacctaac agaatcaaaa atggaaacaa aaagaaacca
    15301 taatagcaaa accataaata acgattgaaa tagcgaattc gccgaccacg atacttgaaa
    15361 aaatgagctt tcaattgtca cattcctcct ttctgttttt acttttcctg tgctaaaaac
    15421 ttttgacaaa aagcaactaa tacaggaata tcacatttag taaaaaaaca taatcgaaaa
    15481 agatttaatc gatttttata agggtgtgca cacatattac atattcgtac tatacgaatc
    15541 caaatcactt cctgatgatc ttgtttccac tggtacggta atgaaaaacg aacaagatca
    15601 cgtaaaaaca tacactgccc aataaccgca caaatatatg catttgtttg tacaaaaatc
    15661 gttggattgt ctccaaaata ctcaatcaat tgttggatat tttgataaca agcacaatct
    15721 ctcaaagtat ttgattggtt ttatctgaat tcaaaatctc cccttccttc tatcttagat
    15781 aaaaagaata ggaagactcc ttcctattct ttcaaaaaaa ccttattttt tctctttttc
    15841 cttagaatca acacttggtt gtttttgatc taaacctttt tcttgtgatt gtttcatatt
    15901 aggattattt gttggagctt ctactttctc taatcctttc gcataaatca ctaaatctga
    15961 atattcacga ttgccatctt gtgctggaat atataccaca tgatattctg gatcaattaa
    16021 tttcacagga tcacgtcgtt taaaaccagt caaatctaca tctgctggaa atttaactcg
    16081 tcgtgcaatc tttggttcat ctggatttcc aaaaactaat tgtgctcgct gtgatcgaat
    16141 ttctcccgta taatcgcctg tttcattatc aaatacacga tcagactctt ctaatgcgcc
    16201 aaagcgtacg gctcctaaac aagtttcatc taatgcttct gtaatgtcat aattatttgg
    16261 aaattttaat cccatcttac aaaacctccc caatttttac accagttaaa aagacaccaa
    16321 catcttgata gccagttgtt cgacgctctg tttgtcccat atcatttgtt tcacgactat
    16381 tcactcgttc tttacgaaaa acaaaataag cttcttcaaa tgaaatacgc acctcttttt
    16441 ctggtaatcg taatctttta tcctcttcag ctgtgagata aacaaaaaaa gcaggctgtt
    16501 cttctcgcga acactctgct tgtaattgaa catatcgccc agacacacca ttaatttcct
    16561 ttggtggatt aggttcccgt gaacccaata aaaatacttg acctaaaaac tctttcttca
    16621 tacgcaatgc tttttctgcc ataaagtttt tcctcctctt aaaaaccaaa ataaattcta
    16681 aatatttcta cattacaatc aaacaagcgg ttaaaaatcc taaccgcttg ttcctcatga
    16741 ctaatctttg gctttacgta ctttataaag tgttatacct aaagcaatga ctaatactac
    16801 taatccaaga accataagta tactacttgt ttgttcacct gtttttggca acattggtac
    16861 aacagtagct ggtttaaccc gttgttctgg tttcactggt tgcggtggtt ttggcgcttc
    16921 cacaatttga accgtttgat ctttgtttgt tagatctaca ttgtgtttcg ccacttcttc
    16981 aaacgtttct ttctcatctt ccgttttcgc ttggagccat tccgcaaaac tcaagccttt
    17041 tcctgcaaga ttgcgaccgt ccactaagaa ttcaaataag aattccatca tttctttatc
    17101 ggccgcaaag actttttccg catgagtgcc ttcaaatggt gtgccgtctg gtgttaagta
    17161 gccttgaaca attaagcgat agatttgacc aatcgcaaga ccgtctactt tgacccattc
    17221 aagcacagtt tgatttggca aggccaagat ctcttttccg ccatttttat tcgtcgcttt
    17281 cgtcgtaatg gttggattac tgattttgat ggtttggtca ttgtcggtaa tatctgcgtg
    17341 agaagccaat aatacgcctt ctctaaacag atcttcaaag accacgactt ctttgcctcg
    17401 caacgcacgt gcgtctagaa taaagtctag attgactgta ccatccgttg tttctgccac
    17461 aaacgttaag gtacttgtga cttcttttcc atctactagc actggttttt ccgttacttt
    17521 gtccattaga acaccgttga ctgtgtatgt ttttccaacg accaaatcgt ggtatttcac
    17581 agcgtctgta atggtgactt tcgttaatgg attaacctct ttcaagccag tgggtttatg
    17641 tgtagccgtt gtacgtacac ttgggttagt tactcgtacc gtttgccctt tgtcgttgat
    17701 gtctttatgg tttgctagtt cttcatcatt tctaaaaaga ctttcaaaca cgacgatttc
    17761 acgaccattt atacctgtca aatcaaaggt aaatggtacg atcaccgttt cattttctgc
    17821 tttggcaata aagccaacac tcgtttctac cgtatttcca tgcacaagca agggttcacc
    17881 ggttgcttta tccattaaga tccctttgac caagtatgct tttcctggaa gaatctcggt
    17941 aatttcaacg gtatcgttta aggtaaacaa tcctgttggg tctgcgactg tcaatccgtc
    18001 ttcaaagaca gccgtggtat gaacggttgg attattcact ttcacacttt gggcttcatc
    18061 gttgatatcc gcatgtgctg caacttcaat gccatcacgg aaaagttttt caaaaacaac
    18121 gatcgtttga cctttcagaa cactagcatt aaccacaaat tcaaggtctt ttgtgccatt
    18181 gactttgtct gcaataaagg ccaaggtact tgtgatttct ttgccatctt gtaaaattgg
    18241 cgcattcgtt gccttgttca tcaatactcc tgaaatggtg tattcttttc cgacaaacaa
    18301 gttggtataa gaaacactgt ctttaatgac gatcgtttct aatggatcaa ccactttttc
    18361 accatcggct ttatttgacg cttgtgtttc tagttttggt ggaatcaagt aattacgtac
    18421 agaaaccact aacgtttccc catcatctgg cgcattttgt ttgaatgcaa ccgtgaatgc
    18481 ttgtttatct gtatttggtt ggaaactttc taatggggca ttttccaaga agtaatagtc
    18541 atcggcaact agacctttca ctaaaatttc cccgttttga tcagtggtat attcaccaat
    18601 tgcttgattt ttaccgttat acaaggtaaa gttcacacct gcgagcggcg ttttcttctt
    18661 gttccattct tcatacttga ataattttac acttttccgt gcttgacggt tcgcaaaatg
    18721 gatcactttg atcggttctg tatcattggt aatcgagaac actaatgggt tttgattcaa
    18781 aacgtaattt acgggggctt tgatttcttc caaacgatag cgatcttttc cataagtaag
    18841 tgtaccgtta gttaggaaaa agcctttttc attggtttta aagatatccg ttgtttctgt
    18901 atcatttgga atctccattg tgacataacg attggctaaa gtatcaaaaa tcttgaattc
    18961 tgtattagca agtggaatca cttttcctgt ttcttgatcc actttcacca ctttaagacg
    19021 ttgttcaatt actttatctt ctaaaacata atggaaagtt tgcccatttt cagaaattgt
    19081 gacttcaagt ggttcaaata gtttataccc ttcttttcct ttggtttcag aaagaatgta
    19141 cgtatcaaag acaacggtat ttttaccaaa agtagcataa ccatcattgt ctgtcacaac
    19201 ggttttcacc actttgccag ttgtttttga cgtcaaagtg atttcaatgc cagctaattt
    19261 tggtttgtta tctggattcg ttgaatcgac taaatcttta ttagcaactt tcactaaatc
    19321 aatggttcct ttgatcactt gatcttttgc ggtcgcattg acagtttttc caggttcaac
    19381 aacaatttca attgcttcat cagaaagcac ataacctttt ggcgctttga tttcttttaa
    19441 aacatatttg ccaggatcaa gatctttaat ttctgcctgt actttgccgt taattttttt
    19501 caaggtaatt tctttaatct ttttcccatc tgcttgatac aaaccataga ccgcattttc
    19561 taaagaagct gcaccttgtg ctttcacacc agtttccgca tcttctttaa acacacgaat
    19621 gtttccttgt tttagaattt gtaaattaat aacagacgca ttaggttctg ttggatgtaa
    19681 cacaccaatt gtttgagctc ctggacgacg ataggctaat ggcgcacctt gaactttaat
    19741 tttattcaat tgaatttttg ctttatccgg tgcctctttt gtgactgtaa tccatacttc
    19801 attgccgtga atagatacat tgacaccttt tggtttttga atgtctttca catatttcaa
    19861 aaaatcattt ttattcttta ctttcaacgt ttcgccaatt tttaccgtat gtgtttgatt
    19921 attaaaagtt gctttttcac caaagttatt aatcaaacgt tgaatttctg cttttcgacg
    19981 atcataatca acacggatat ttttgattgg gatttttgtg cccaaagctt cccaaatcat
    20041 aaattgtgcc gcaatgtatt gttcatcgga tttgtcttta tttgtgacat atcctaaata
    20101 agagatcaag cttgtttttt tccgtacatt tgaatttttc aaatagtttt tcaaagcagt
    20161 agctgtataa acttgacctt ctgcggctga gacaccaggc tcaatacaaa acgccacttg
    20221 tccattaatc tcaaaacgaa ccatataatt taaagtgaag tttagattgt tcggactaga
    20281 agtaacacca atattttcgc cccaatcaat tttccgacca cctaaaacag ctgcattggt
    20341 tgcacggcga acacgaaccg aacgattggt tggtactgtt actaacagtg taggtgtacc
    20401 tgtttttgga atgttctgct cttttttctt ttgattttca atactagccg tagattcttt
    20461 gtttggtttc gttggttgat tttgactagc tgcggttgaa gagattgttt tttcaacgtt
    20521 ttcctcattt tttccttctt tgtcagcagt agccgctggt tgttccactg tttcttctat
    20581 tcgtttcttt tcttccgctt gtttctcaga agactctggc tgcacagaag gcgttgcttc
    20641 ggcagctttt tctccttcta gagtggacgt ttctgaagca ggggttgtaa ttgaggcagt
    20701 ttcttcaact ggttgtgaag taccaggact attccctggg tgttgtgttt ccccaatcgt
    20761 ctgatcgaga gtcgttttgg aattgaccgt tggcgcttct gtcacagggg cctgttcaac
    20821 agtggcttca ccagctggga ccccggcttc tgctggttgg acttctgtca cttcagaagc
    20881 gacttgggca atggcttcca tcgtaggttg tatagccgtc gtttcttctg catgtgcttg
    20941 agcagttccc accaagaaac agaattgaga aaaagccacc aatgcgagtg ctttcaacca
    21001 attcattttc gtttttgcat acacaagaat tcctcctttt cctgagaatt ttatataata
    21061 aaacaaaacg ccgttaccaa aagtgataac gacgtgaact gtctcttcta tttttatctg
    21121 gcgctcttat ctgaacacat ttcatcaatg attttaccct cccactataa ttacagaaca
    21181 aaaaaagaac ctgcttcgtg gaaatcaact gtccatttcc caattggaat accagctttt
    21241 ttggcaactt caccatcacc aaatctcatg ccataccaat tactaccttc atccttaatt
    21301 tctttccaac catatgacat agcttcatct aatgaatcaa aaatcatgac actattgcca
    21361 attgttacag gatctggctt aagatcttct ggaagagaaa tatcaatcat accataatga
    21421 tccgattcct cagtattatt gtcattacta gctactggtt tggttgttct actggcttat
    21481 tttgatacaa caagtactct tattcttctt ttacttctcc gttttcaatt tcccattcaa
    21541 accactccgc aaagtcttgc ttaaaaccat ctactcgata cctattttgt aaataggcat
    21601 cttctgacgt cgtaggatct aaataggtag gtttattctc tggacgagca tagacaccta
    21661 cccatgtttc gtaatctcct tcaaaataac tatctaccaa atagcctttt tttctaagaa
    21721 tctcccgaac ttgattttta attattgata cttgttcaaa accatcactc attctatcac
    21781 ctcaaataac tctagattct cataaatatt cccgacaatt tcaatcctat caatgatctc
    21841 taacaaatcg ctacttatgc ttccccattc gtataagaat ttcccttccg caaaataaat
    21901 tttccataaa cttcttcatg atcgtcccaa ccaatatcac tctcgaaaaa ttccacgttg
    21961 ttcttatctt ttagctcagt aaatgccata agttcaacat gttttccaac ctcgaaacaa
    22021 tcacaccacc catcaaccgt tacacgtgtg ccttcaatac ctaagaaact ttgtcctcgt
    22081 gtattaaaca ctaaaacttt ccgcattttt tgctcattaa ttaatcacgc gcgaaatcta
    22141 ggaatcacaa cttattcgct tcttctttat aa
//
LOCUS       DADLIO010000047        21924 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.047, whole genome shotgun sequence.
ACCESSION   DADLIO010000047 DADLIO010000000
VERSION     DADLIO010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21924
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.047"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            283..522
                     /locus_tag="JOX41_001874"
     CDS             283..522
                     /locus_tag="JOX41_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449616.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(884..1144)
                     /locus_tag="JOX41_001875"
     CDS             complement(884..1144)
                     /locus_tag="JOX41_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449617.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(1329..1826)
                     /locus_tag="JOX41_001876"
     CDS             complement(1329..1826)
                     /locus_tag="JOX41_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HAY6449618.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            complement(1956..2666)
                     /gene="budA"
                     /locus_tag="JOX41_001877"
     CDS             complement(1956..2666)
                     /gene="budA"
                     /locus_tag="JOX41_001877"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HAY6449619.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(2679..4343)
                     /gene="alsS"
                     /locus_tag="JOX41_001878"
     CDS             complement(2679..4343)
                     /gene="alsS"
                     /locus_tag="JOX41_001878"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HAY6449620.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(4548..5210)
                     /locus_tag="JOX41_001879"
     CDS             complement(4548..5210)
                     /locus_tag="JOX41_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAY6449621.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            complement(5220..6035)
                     /locus_tag="JOX41_001880"
     CDS             complement(5220..6035)
                     /locus_tag="JOX41_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAY6449622.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(6297..6740)
                     /locus_tag="JOX41_001881"
     CDS             complement(6297..6740)
                     /locus_tag="JOX41_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HAY6449623.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(6874..7212)
                     /locus_tag="JOX41_001882"
     CDS             complement(6874..7212)
                     /locus_tag="JOX41_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAY6449624.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(7200..7577)
                     /locus_tag="JOX41_001883"
     CDS             complement(7200..7577)
                     /locus_tag="JOX41_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAY6449625.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKEIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            7801..8994
                     /locus_tag="JOX41_001884"
     CDS             7801..8994
                     /locus_tag="JOX41_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAY6449626.1"
                     /translation="MTTYQRKVLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(9160..9582)
                     /locus_tag="JOX41_001885"
     CDS             complement(9160..9582)
                     /locus_tag="JOX41_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAY6449627.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            9977..10171
                     /locus_tag="JOX41_001886"
     CDS             9977..10171
                     /locus_tag="JOX41_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449628.1"
                     /translation="MVAGSLLSGCGATTSTTQSTSSDQASSSSTTISESTADSSKEQE
                     QIEKKKEEKQKAEKAALEKK"
     gene            10168..10662
                     /locus_tag="JOX41_001887"
     CDS             10168..10662
                     /locus_tag="JOX41_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449629.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQEAIAQQQAEQARQQSA
                     AEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSK
                     CYGN"
     gene            complement(10824..11996)
                     /locus_tag="JOX41_001888"
     CDS             complement(10824..11996)
                     /locus_tag="JOX41_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAY6449630.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(12202..13017)
                     /locus_tag="JOX41_001889"
     CDS             complement(12202..13017)
                     /locus_tag="JOX41_001889"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAY6449631.1"
                     /translation="MTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVE
                     TKAPDGYQLTNPQKETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNTI
                     TVENVQNYGDFHFIKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWS
                     DEVTGSDWEEVKLISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDD
                     DPTTSDETTIDNQPKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            complement(13167..13613)
                     /locus_tag="JOX41_001890"
     CDS             complement(13167..13613)
                     /locus_tag="JOX41_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HAY6449632.1"
                     /translation="MKNIKTKIWTFLGTAIMLLPFVLGLGTAEVSAAVSPTPENVTVN
                     LHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKDTAVPADATPFA
                     SVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLP"
     gene            complement(13610..14614)
                     /locus_tag="JOX41_001891"
     CDS             complement(13610..14614)
                     /locus_tag="JOX41_001891"
                     /inference="COORDINATES: protein
                     motif:HMM:NF037639.1,HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAY6449633.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKIKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            complement(14654..14983)
                     /locus_tag="JOX41_001892"
     CDS             complement(14654..14983)
                     /locus_tag="JOX41_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HAY6449634.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     TEIKTSD"
     gene            complement(15109..17436)
                     /locus_tag="JOX41_001893"
     CDS             complement(15109..17436)
                     /locus_tag="JOX41_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAY6449635.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSAIETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            complement(18279..18572)
                     /locus_tag="JOX41_001894"
     CDS             complement(18279..18572)
                     /locus_tag="JOX41_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HAY6449636.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            complement(18975..20153)
                     /locus_tag="JOX41_001895"
     CDS             complement(18975..20153)
                     /locus_tag="JOX41_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAY6449637.1"
                     /translation="MEKTDRFKKQISSTGRITWYFQAYRTTRRGFNSKREAQLAYLEM
                     EKQQRLKKKIVASNDKFSVVGEQWFQYYRSLNEQKEITYDKREEQLKIIVRWIGDKKL
                     SDLTPECLQELLFTLKECGVNGTNVGYAKNSLQSLIQVLNMIFKYCQRKNLISENPMK
                     SVRMPKYQLTVTDLKEAINNIEDKFLTVDELRTFLNYGIVHEELPMSVLFHVLFYTGC
                     RVSEALALQPGDIDFKRNEILFYKQTAVKGKSKDFRIETTKTVSSARRVLVTPLVMEK
                     LQQLIKALGEMRQHYRFIIEETYLFVYLDSSKRGVPYRREYVNDHVKRCVNRSGINKP
                     FHTHLARHTMASLVAEHCSWEVLKDRLGHTDQTTSKIYRHLTSNEKVKPLIAFSSLES
                     "
     gene            complement(20257..20571)
                     /locus_tag="JOX41_001896"
     CDS             complement(20257..20571)
                     /locus_tag="JOX41_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAY6449638.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            20678..20893
                     /locus_tag="JOX41_001897"
     CDS             20678..20893
                     /locus_tag="JOX41_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449639.1"
                     /translation="MKQGIADIKIIKEILEKSTANAIAFGTGINLSTVKKLKSGERAE
                     EKLNLADAIKITEFGMKNMPTKIEIWK"
     gene            complement(21193..21435)
                     /locus_tag="JOX41_001898"
     CDS             complement(21193..21435)
                     /locus_tag="JOX41_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAY6449640.1"
                     /translation="MKQNKRYIPFIPLTTIKAAASGDSIAMSIVLSKYQNYISRLAMK
                     PVYEEEKGMVMYVDEYMRRQLETKLIEKILEFDTTR"
     gene            complement(21422..21850)
                     /locus_tag="JOX41_001899"
     CDS             complement(21422..21850)
                     /locus_tag="JOX41_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAY6449641.1"
                     /translation="MGDSEETHIQHTFDSFCKKVVCNEALNIQKKYARFRQRQISMEI
                     LEQKGLGTEFYYLEPNLNSSGTFIVLGMKIFISNEELANAIAALPSQRQEIIFMSFFI
                     GLNDREIGDIIGKSLGSVWYQRQMALEELGKYLGVKYEAK"
BASE COUNT         6455 a         4314 c         3705 g         7450 t
ORIGIN      
        1 ctatcctcct agcaactatt taaataccca aaaaaattac ctctagataa tatcatacct
       61 acgttttcac ttataaattt tttcataaaa aaagcgttta gaggcataat cgttaataca
      121 gatggtaacc aatgtatctg gtttgaactg ggatatcacc ctctccatat atgtattact
      181 aagactaata gatactataa aagacttgat agttttgcat tgattttgcc taatactgag
      241 cataggtgta tgctaaacga tactataagg agtgtgtaca taatgaaaag aattctgttt
      301 atcagtttat caaatttatt gttacttact gcttgtggga cttctgcatc aaagaacata
      361 ccttcagata cgcaaatttc gaatagtatc gattcaacaa tttctacaaa tgagaaaaat
      421 tctccggtag aaacttccga tataaaagtt tctacctctg caaaaaacag ggtaaagaaa
      481 ctgtcagcac gtctccttta tttcaaacaa actctgaatt agcttcttca tcttcttcag
      541 caaataatga tgatagtttc gcgtttactc ctaactaaat gcaaccttta caaatgcttt
      601 acgataacaa gcctgagcta aatgatcctg atatcagttt tgcatttttt gaaatgattg
      661 gatcggatga tctttttaaa actactagtt tgtctatccg aaaataggac agttctggca
      721 gtataggttt ttatcgagtt tctccaccag gcctcgttac agagacagat tctctaggcg
      781 aaccttttga ataaatcaaa aatcatgaac aatcactgcc aactaaataa agtgccttca
      841 aaagcttggt cttctcgctt ttgaaggcac tttatttaaa tctttatgaa actaaagtat
      901 gttcatattt gttgctatag ttatatagat attctgttgt ttccaactca taaacgtgag
      961 tatattttgc cactactttt ccgcattttt ctaatatttc attgcgatcg acgtcatgat
     1021 attcgtctac gcagatcaca acacaatttt ctaatttact gattacttct ccaaccactt
     1081 tttgtttcaa gccaataggt tggcaaatat atttttttcc taaaatgata gtttcgttat
     1141 tcatatttca tccatcctta atgtttttcc attatttaaa atgataatac cattaaaata
     1201 tgattatgaa aatcaataac acttgtgatt ttataaaaaa ataaaaaaac cgaaaaacag
     1261 aaatgcccac tgtctttccg gctcttttta ttcttgattt ctcttctttt ttgtttcaat
     1321 agacgatttt agttattaat aaatgaaaaa gcatttatat taaaatttgc taataaaaga
     1381 tctacatatt tttctagaaa tgcttgatcg atttcatcat accctttcgt tactccgcaa
     1441 tcgatatcta aaacaccgat taaattacct tcttttacca ttggcactac gatttctgat
     1501 tgtgcggctg aatcgcagga aatgtaattt gcatgggttt tgacatcatc aacgatcaat
     1561 gtttcttgtt tttcagctga ttctccacaa actccttttc ccatcttgat acgtgtgcaa
     1621 gaaactcgcc cttggaacgg tcctaaaatc aattcattac catcgaataa ataatatcct
     1681 gcaaagacag tctcaggcaa agtctcattc aacaatgcag atgaatttgc taaatttgct
     1741 aaccagttat cttctgcttc taataatcct tgttgctgta ataataaaat ttcgtatgca
     1801 tcttttttct gtttttctgt ccacatgata aaaaccgctc ctttttgatc tatggagaag
     1861 attatagctc agtttttttg taaacgctag gtttcctcct caaaaaaacg agatacgtca
     1921 ggttaatcac cttgaacgca tctcgctgtc tttttctatt ctgcttgttg gatttctgct
     1981 gctaaatcag cataatcaat cgtttcgtga acaaaagtcg gatcatcaac tggaaaatgc
     2041 tgtacaaggg acgagatgcg gctaatctca acttttcctt cagccacttc aaaatccatt
     2101 acatgtccgc caaatgtatg tgtatcatcg ataaaatgca agtgaaatcc cgctgcagca
     2161 actccttgga ataattcagg cgtaaagaac ccgactaatg ttccttggac attgctttgt
     2221 tggaattctg gttgagactc tgaaattttt gctagtcttc tgtaaggttt ttcttgcttc
     2281 ggcatgatac ggatgtgcat atttttgaat aatccagtta tcttcactgc caaaaatagg
     2341 ttttccccgg cttctcttac taatatgtct tttttcaatt gttctccatc tgcagttttt
     2401 gagacagaaa aactagtatc tggcgtaaaa tctgtaattg ctgcataggg ggtaagttca
     2461 cttccatcta attgggcaac tgagccatct gatcttcctt gataagctac gccatctaaa
     2521 aagatgactt caccatcaag cccatgcaat gttcccaatc ccagagttcc tttttctaat
     2581 atatgagcaa tcgtttctgt tccatccatc aagccagcca tcaaagctcc taatgtcccg
     2641 tgctggtata agattttttc agtcatgtcg acacttcctt aatagaattg atctggtaag
     2701 attgtttctc ccaatttctc attatcacgg taatcaatcg gaatatcaat aattacgggt
     2761 ccttctgtcg caaatccttc ttctaaagct ttttctaatt cctctacact tgtagctcgg
     2821 attcctttag cgccaaaagc ttctgcatat ttcacaaaat caactggacc aaagtctaca
     2881 cctgacgccc gctgatattt cattttttct tggaactcta ccatattgta gtgtccatca
     2941 ttccaaatca aatgaacgat attcaatttt ttacgtaccg ccgtttctaa atcctgggca
     3001 gagaataaaa atcccccatc gccggaaact gatacgattt gtgtatttgg acgcaccaat
     3061 gcagcagaaa tcgcccatgg caatgcaaca ccaagcgttt gcataccatt actgaataac
     3121 aaatgacgag gttcataact tctaaagtgg cgtgccatcc aaatataatg actacctaca
     3181 tctacggtaa cagtcatatc atctgttact tttgactgaa gcgtgttaat aacttctaaa
     3241 ggatgcaaga tacctgcttc tccttttgat tgaacaatgt cccgctccgt taattctgct
     3301 tgaagagatg ctaaatattc ttttgcatct tctgacactt gttgaggctc taatgaacct
     3361 gtcaataaat caagagtggc tgagatatca ccgatcaatt ctctttcagg ctgcataaaa
     3421 ggatcgattt cagctggcgc ttcatcgatc acaatgatcc gcgcatcttt ttccgcattc
     3481 cagtttcttg cttcatattc gattggatca tagccaatag caataactag atcacttcgt
     3541 ttcaaaagca tatctcctgg ttggtttcta aataaaccca cacgaccaaa gaaatgcgct
     3601 tctaattcac gtgagatcac tccagctgct tggaatgtct ctacaacagg caatgctgtc
     3661 tttccaacta attgcctgat ggctaacgtt tctttttcac ttgatcctcg catacctact
     3721 aatagtaccg gtagttttgc ttctctaatg cgttcagcta ggtaacggat atcatctgca
     3781 gaagcagaac ctaatttagg atcgctcaat ggcttgatga cattcccttg gacaggtgca
     3841 tccactacat cttgcgggat actgataaag ctcgcgcctt tttttgaact cttagccata
     3901 cgataagcat tggcaatcac ttctgaaatt gtttctggat cttggatttc tgcactgtat
     3961 tttgtgattg gctggaacag tgctgcatta tccatgcttt gatgggtcaa cttcaataga
     4021 tcgcttcgtt ttacttgtcc ggcaattgct aaaactgggt caccttctgc tgtcgctgtt
     4081 accaaacctg tagctaagtt actagcacca ggaccacttg ttgcgataac tactcctggc
     4141 tctcctgtaa tacgtccgat tgcttgtgcc ataaatgcag cattttgttc gtgacgagtc
     4201 acgattaatt caggaccttg atcctctaat tcattaaata caccatcgat ttttgcacct
     4261 ggtataccga atacataatc aacatgatga ttaatcaaac tttctactac agatttcgaa
     4321 ccttgtttca ttttttcgtc cattgaacat cgtccttttt atgctttatt tttaattatt
     4381 agttagaaat aatcacaaat aattgataca gtttctaaac ctgtttcatt caaaagtata
     4441 gcacgtttta tttcatttgt ttagccatat gtttcaaaaa atgaaaaaga atgacagttt
     4501 ttacataaaa actgtcattc ttaattgaaa gtttcaattt ataaagtcta cagatccata
     4561 gttctcatca atttacgatt gttgaagtaa atcaaaccaa atacgataga aggacctagt
     4621 agaatacacc attggggctt tacgaaaaag aagagaaaca aacttgtcaa tagtaaaaaa
     4681 tctagtaaac tcacatacca ttttttcaac gtatagtaga acgctatccg tagaacttga
     4741 tttggtttcg acgctggatt tctcacctga aaataccagt agttgatgct aaaggaaact
     4801 gataaacaag caagtaaaac aaacaacgga atcaaccatt ttccataaga aaaacgtata
     4861 aaaaagaaac aatcaaaaat cattatcaca ctaactatcc aagcaaatag ccaataaaaa
     4921 aatcccttta gccaaaattg gcgaaacgtc tttatgaaca aacgtactgg tgaaaaactt
     4981 ttttcttttg ctaattcttc tgtcatacct atcatcacga tgcaacctgg accaataaaa
     5041 agtaaagaaa aaataaagga aaagacattc cttccatcta tcgacaaaag gaacgcagct
     5101 gctatataca agatattgac acaccaaaaa caaaggctac ttgccaatga ttgatacaac
     5161 caataaaaga attccatata aacatttttg tcaaaacgct gctctttcat aatcacctcc
     5221 tattccttca ttcctgatga agcgatccct tctacaaaat atttttgcat cgctaaaaat
     5281 ataaaagcaa caggaagaac agaaacaact gaggcagcca tgattaatgc gtactctgca
     5341 tcaaatagcc caataaacat tttcaaccct aactggattg ttttattttc cgtagaagac
     5401 aaataaatga atggccccat ataatcgttc catgtattaa cgaatgtgat gatcgtcaaa
     5461 ctggcaatcg ccggttttgt aagaggtaaa atgatcttgc gatagattcc ccactctgat
     5521 aagccatcga tccgcgcact ctcacataaa gaatctggga tactactgta gtattgcttc
     5581 aacaagaaca caccaaaagc attgaacgct tgtaatagca ccaacgacca caacgtatat
     5641 gttaaaccca cttttctcat cataatgaac tgcgggatca tataagactg ccaagggaca
     5701 gcaatcgtgc cgatatatgc taaaaataaa atatcgcgcc ctttaaaatt tagtttagaa
     5761 aacccgtaag cagcaaaact agaagtaaac aactgaatca acgtgatcac aacgcttaaa
     5821 aaagctgtat tcttaaaaaa tgtcactaaa ggaatacgag accaaataac cagataattc
     5881 tctaaatgcc aagttttagg gatccattga atcggaatcg tgaacacttc attatttgct
     5941 ttgaatgaag cagaaaccat ccataaaaaa ggaatgatcg tcaataaagc taatacaatc
     6001 agcagaatca tacccaacca ttgaataaag ggcatgtttt ttgaacgaat ttttgctttt
     6061 tttctttcat ttcgaacacc tccaaagtta taatcttcat ttctttgtaa tgattacaat
     6121 ccagaacaac ggttattata gctgattcat ttccgttctt cttatgtttg taagcgctta
     6181 tttaacaagt tatgtaaatc tctttatttt ttttgattta aaaatgaaaa aatacaaaag
     6241 caagactgtc atacgtctcg cttttgtatt gaaatttctt caattagaga tacttattac
     6301 tgttcaaaag cttctttgaa acggtgaatc aattcattga ctacaggtga taaaatccga
     6361 ttctttttcc agactagcat gcagttcgtt tcaatcattg ggtcaagcgg aacgaatgtc
     6421 actcgctttg aaagatgact tacagcacct tctatgacta aagcagcacc tacctgattc
     6481 tcaattagcg caaatacatt gaaaatcaaa ttgtacgttc ctgtgatcag caactgctcc
     6541 ttttttatgc ctaaccagtc agcaaacatt cgctgtattt ctggacgctt tgagatcaaa
     6601 agaggtacat tcgcaaagtc ttcttttgtt atcacgtctt tttttgctaa aacagaattt
     6661 tctaaaatga gcaatcccca tttttccttt cttggtaaca aaatcgtttc gtatttctct
     6721 gtatctactg gatctagcaa aatcgctaaa tctaacaggc ttttttctag tcactccgtg
     6781 atatcatcac ttgttccgct gtggatatga aattgaacgc tgggataatc acggatcaac
     6841 ttttctagta atagtgccaa tgtattcgaa ttatcagctt ccacacagcc gatcgtaaat
     6901 cggccgctga ataattgttt ttttctgttc tcgaattctt gagtggtttg attcgttaaa
     6961 tctaaaattt cttctgctcg gcttttttag aaaataacct gcttctgtca agatcatttt
     7021 gcggttttcg cgtacaaaca gttctgttcc tagttcctct tctaactcct tcagttgtcg
     7081 gcttaaggtt ggttgtgtaa gatgtagaac ttctgcggct tgagagattg ttccttcttc
     7141 tgcaattgtc caaaaatatt ttagtaagcg taactccata gcgatgctcc ttgatttttt
     7201 tacttgatac attccatttt atttctagat aacacacgat catatttctt gatttttcct
     7261 tgtaaacgtt ccaaacactc ttgcatttca gcaatttctt tcgtcaaaag ttcactttct
     7321 tcaatcaaaa gcttacgccg ctcaaataca gttgcttctc cttcgctaga taggcgaata
     7381 tattcaatca aagactcgat cgataatccg gcatttcgca tacagatcgt aaagtcgacc
     7441 cattttaggt cttcttctgt ataatcacgg attccgcctt ttgtccgatt aactggtgga
     7501 atcaacccga ttcgttcata atagcgcaat gtatcggccg aaatgccctt ttcttcactg
     7561 acttgtttga tattcatctg atcactcttt ctcttaattt cttgccactt tacttatgta
     7621 ttttatttat tctacaactt taagtgtact ccaagtcaat actcatttct attaaaacta
     7681 agctggatta tctatatcgg ttgtttgtgt attatttcaa ataaaaaagt cttgtttttt
     7741 tattcttttt tggatatact tttaacaatt tagggaaatt ttaggaaaag gggtataaaa
     7801 atgacaacgt atcagcgaaa ggtattatta tcgacatcgg cgggaattgc tttagagaat
     7861 atggatatta tgtttttagc tttttcatta tcttcaatga ttacttcttt tcatattagt
     7921 ggtacgcaag cgggtttcat ttcaacgatc actaatttgg ggatgctcat tggaggtatt
     7981 ttttttggca tcatagctga taaatatgga cgtgtgaaag tattttctca aacggtcctt
     8041 ctgttttcga ttgcttcttt attgatgtat tttgcttcaa acatctactt ggtttatctc
     8101 tttcgcttta tcgcaggtgt aggagcggga ggagaatacg gggcgtgtat gtccttgatt
     8161 tccgaaagtt tttcaaaaaa acaaattgga cgagcttctt cggttgctgg tattggtgcg
     8221 caggtcggtg cggctttggc tgcgatttta gctgctgtga tcattccaac gtttggttgg
     8281 aagatgttgt atgtcgtagg tgtactgccg gtgttgatgg tcttgttcat tcgtcgcggc
     8341 ttgactgaac caaaggaatt caaatctgta caatctgccg aaaagaaaac caaacttagc
     8401 agactgtttg aatcaaaaca tcttgcttgg caaacatgtg gccttagtat catggtaact
     8461 gtccaaattg ccggctattt tgggttaatg aattggctgc cttcaattat gcaaaatcga
     8521 ttagggcttt cggtttctgg gtcttcattg tggatggtca gtactatttt aggcatgtct
     8581 ttggggatga tgacttttgg cataatcatg gataaattgg ggcctaaact agccttttct
     8641 ttgtttttaa tttgttcatc cttatctgtc tatctacttg tgttagccca tagccagtgg
     8701 agtttggtag cagccgctgt gatagtcggc tactttatca atggcatgta tggtggatat
     8761 ggcgcagtga ttagtagttt gtatccaaca gaaatccgcg cgacggcgaa taatttcatt
     8821 atgaaccttg gacgagctgt tggtggtttt tcttctatcg tcatcggttt cttgatggat
     8881 cattatagtt taactgccgt aatcttgttt ttgagcggta tttacctagt cagtctgctg
     8941 gtcttgacaa ctcttactgg tgttacagca ttaagggaaa gcttgcagca ttgatagttg
     9001 agtctgtaaa tgacaagaaa gaggtgtggc aaaagcttgc atctgcggta ataagaccag
     9061 ccaaatcaaa aacatgagac actgtttccg tttggctggt cgtattactt gatgcagggc
     9121 agctttttca actgctaatt tccttctatc tggcggcgac tattctttga cgtccgtcat
     9181 ttcaaagtac tttactaata acttagcata acgaaaaact gtggatacac tcgtatattg
     9241 agcgtctgca taatcttcca aatttttctc aggatgttga tacatgaatt caatcaaatg
     9301 ataattatat gattttctgt agaaatgaag ataaataatg tagattggga agttctcctg
     9361 cttttccata gaaaagcgcc gattattctc attcttcaaa atgaccttat caggatattt
     9421 ttggaacaat tcttctaaat ctgttagata attcaagata gacttacttg ataccttcaa
     9481 ttcgttttgt agttcttcta ttgaacacca acgttctgtt tcaagcagta aatgaatcat
     9541 tttaattttc ttttgagaaa cttttgttaa aaaagtctgc atattttctc ctcctgtatc
     9601 tactttacta tactacatac aagaaaaaaa acggatacaa atatcatatt gtcacaccgt
     9661 caatagtgca taaacctgtt attatttctc tttttttcct aagtattcta ttgatatgaa
     9721 tcatttaatc gtttattata taaatgtcaa taatctaata ataaaataac gtacatattt
     9781 tattattgca tacttaataa cagaactata gcaaaaaatc ccgtgtatca acacgggatt
     9841 agattaagtt tcctcaatca ctattcataa cacaattatt ataacaagta agtaaacaat
     9901 tgaaaaggac atttattgaa aacggttgtt ttttacttaa ggaggaaatt tagcgaaaaa
     9961 attagttgca ttgtttttgg tcgcaggaag tttgttgagt gggtgtggtg ctactacgtc
    10021 tactactcaa agcacaagtt cagatcaggc ttccagcagc agtaccacga tctccgaaag
    10081 tacggcagat tcatcgaaag aacaagaaca aattgaaaag aaaaaagaag agaaacaaaa
    10141 agcggaaaaa gctgcactag aaaaaaagtg acagaagcgg aatctgcttt gtcacaagct
    10201 gaagcaaatc ctacaaaaga aaactatgca actgcttcag cagctatcca agcgctacct
    10261 gaaaacaaac aagagttgac aagccgtctt gctgcaattg attccacaat caaagcaaaa
    10321 gaagcagaag aagaacggaa aaagcaagaa gaaattgcac gacaacaagc agaacaagcg
    10381 caacaagaag caatcgcaca gcaacaagca gaacaggcga ggcaagaagc aatcgcacag
    10441 caacaagcag aacaggcgcg acagcaatca gcagctgaac aggcctctca gcaggcacaa
    10501 gccgcagctc ctgagcaaaa taatgaacaa actgtctatg tcacaccgac cggttcaaaa
    10561 taccatacac ataaatgtgg aaatggtacg tatacccctg ccactttaag cgaagctcaa
    10621 gctcgtggtt taaccccttg ctccaaatgt tatggaaact aattcaaaag ttatactata
    10681 ataataaaat tcttctgaaa cataaaaaaa tagaagatgg cgttccagat agtaaaccaa
    10741 aaataacagt ttacacgtcc atttcgtcag cttctctctt ttttcattta gtctgttccc
    10801 tctgcttttt tggacatctt cattcattct ttctcaatca aatagtacac ctctttttct
    10861 tttcgcagtt tatatcttcc ttttttcaat ttcattgaaa actgtttcga atgtttatgt
    10921 tttacatgga ttttaagcag gagctcctca tgttgcaagc gatagttcct gccttttaaa
    10981 tcagaaaatc tcactagtcc gtattcatca gaagctttca caaatggaac tttttctcta
    11041 gtaatatagt gtttgccgtt gagcgttttt acagaaaaga ccattccttc gattggtcgt
    11101 ccgtttgtgt tctttacata aaaagataaa ggatagtttc gcttagcgat ggccaaagaa
    11161 tctaaataag cgatgagtag ccaaactaag ccgattgatc caagtagtat accgataaac
    11221 caaataaaaa atttccattt tttccattga tcaattcctt ggatcgcttt ttttgcctct
    11281 tttgcttgat aaggaatacg atgccccgtc acaagcagtc gatgtgtatt gaccatataa
    11341 ggagtacagg taagcaaagt cacgagatct ctgccttttt ggatacccaa agaatctact
    11401 tcatcaggta agaccacttg gattttttct acttgatacg ccaatgtctt tccattgatc
    11461 tggatgaaaa actggtctcc ttttttcaac ttaggcaaat ctgtaaataa ttttgcttct
    11521 gggagtccac gatgcccaga aagaacggca tgggtgtttt tcccgccagt cggataagaa
    11581 ctttcttcca ataatgacgt tcctttttgc aaaaatattt ccgttgtctg atcgaatata
    11641 ggtaagctga cattgatttt tgggatttcg atgactccaa gcatatgttc cataaaaaag
    11701 gcattactag gtaaatcttt taatgctttt gcatcaactg cttggttgaa actgcctatc
    11761 cctggtgata cgttttgctc tgccaactgt tggtttttct ttgtcatttt ttcctgctgt
    11821 ttttttattt cctctgaatt cttattcgat gcttgctttt gataatggat gatcatttgc
    11881 tgggcaagaa aatcattcag tgaatcttct acaaaaggat aagaaaagat cccgatccca
    11941 acgactaaaa tgattgccat gaagatgtcc agtattctta ttctgctttt attcatcatg
    12001 tccacctatt ttctaatatg tatatgaaga ggttgtgaaa tcagcgcctt gacctgagta
    12061 ttagcgaagc aaacggcaaa atagttcctc ctattttgcc gtttgttgag cgaataccaa
    12121 gagaccgacc acttgtcaca acctttctcc ccatttgaat cactatcgtt tatttatcgt
    12181 atgatttttg tttccaatag tttaagcttc tgtttcttga tggcgttttt tgaaatagat
    12241 cactgctcct ccaactaaag cagtacctac caagatgaat acgatgatcc ccataccacc
    12301 agttgaaggc aagattcctt taggttggtt atcgatcgtt gtttcatcag aagttgttgg
    12361 atcatcatct actgtaaatt cagtgtacgc agcttcattc ttaggtaatg cgtagccttc
    12421 tggtgctttt gtttcttgaa ggcagtatgc cccttgtttc agcccttcga ttgaaaattt
    12481 cccttctgaa tcagaaatca atttcacttc ttcccagtca gaacctgtga cttcatctga
    12541 ccaagcatat gggtattctc ctgaggcaag gtttgctatt tttttcatta atttaacagt
    12601 tggatctttt gctcttagaa tagaaaattc tgcatcggct aatttttctt gcgtgttcac
    12661 atcttgtttg atgaagtgga aatcaccgta gttttggaca ttttctacag taatcgtgtt
    12721 atccgtagtt gtattttccc gattgactac accgtttgga ttcccaagat tggcttcatc
    12781 tgcgccatgg atgataccgg ttgtttgttg caattttccg ttttttacta taaaagtagt
    12841 ttctttttgt ggattggtta attgataacc atctggtgct tttgtttcaa ctaaagtata
    12901 attgccgtct attaatccat tgacactgat ggatccttca gtatcagttg tgaatgtcaa
    12961 cgctgactca gcaggatcat agagagcgac accagtgttt tcatcaaaac cggtcacgaa
    13021 ttgattctct gaatttttga tctggaattg cgcccctgct aacttatcta cccctgaaaa
    13081 gttcccagct ttctggattt tgatattgct ttctttgatg acatttttag catataggtg
    13141 aatcgtgtct aaaggtttgt cagggtctag ggtaagctta acacgatatt tggcgacgtt
    13201 tcgacaccgg gctttggtgt ttctacaaag acgtatacag catctttccc atcagattta
    13261 cctggaagag tcaggttagc taatccttca ccagaagtcg ttacacttgc gaagggtgta
    13321 gcgtctgctg gaactgctgt gtctttactt ggatagtacg tagcagtgat gtcatatacg
    13381 ttgaattcaa cgccgttcaa cggttcgcta ttcggaaatg tcaattccgt tccgttgttt
    13441 atttgatttt ctggtgctga agtgaatttc aatttatgca aattaaccgt aacattttct
    13501 ggtgtaggtg atacggctgc agaaacctct gcagttccta ggccgagaac gaaaggaagc
    13561 agcatgatag cagttcctaa aaacgtccat atttttgttt tgatgttttt cattttattt
    13621 ccctcctatt gtttcctttt tgttgttttt tataaaacca agctgtccct gttgaaagga
    13681 ctagcaataa ccctaaaatt gagaaacctc caagcatctc ttcgcttgtt tttggaaagc
    13741 ttcctccatt tttttcattt gatggaccat ttgtctgcat ctgaactggc gtttttccat
    13801 tattcgtcgg atttgctttt ggttcgttga tgatttccaa tggtatagga tgaagcggat
    13861 cataactgcc tttttcaact tcaaagagaa tggttgattg actcaatata tatcctttag
    13921 gcggtttaat ctccactagt tcgtaacttc caaaagacaa tccatggaca gaaaatgttc
    13981 catctttact ggaagtaaaa atcgttgctc ttgaatcatc tttggctacc caatgattta
    14041 tcccgttttc ttgcgctaag tattggtcat tttttttgac tagaaattga gcatctgcta
    14101 gtttttgttt cgtttgccga tccactttga caaattgttt gcctcctgtt tggatggcaa
    14161 gatgtgtttc tactgtttga ttgtcagtcg tcaaacgtac atcgttatca aatgtcgttt
    14221 tttcactgtt ttctttcaat gtcatttggt aacggatcgt taattttttt ccagcaaacg
    14281 aactaagatc ttttccagaa tctgataaga caaaaccatg ttttattttt tgtgtgtgaa
    14341 atgtatgaat cttgtctcca ccaatcaaaa aatcgatcgt ttctggttct agccataact
    14401 gaggatcagc tgtatctttg atcgtatagg ttcctatctc gttgatgttc tcaggaattg
    14461 ttacggtgat gagataaggg actttatccc catctgcaaa atctgtctgc ttattctcta
    14521 ctgtttttgt taatgtgagt gcagcaggta ttttttgttc gctctttgga tacaagtgga
    14581 tggtcgtcaa tttatgatta gatgaatctg tcacaggaag cacaacgaca aatggtgctg
    14641 atttttcttt tacttaatct gaagtcttta tttccgtaaa tcggtaaaca gcgtcacgac
    14701 cttgctcatc tttgtccgat gcactaaaag aagcaatgcc ctcttcctcg tctactgttt
    14761 ttgtcacatt ttctgccagt attttttcac tatcactttt ttgtgctagt tttctttgtg
    14821 cgtcttccac actacttcct tctgaccgca gcttgtaaaa ttcatccgag acatcatata
    14881 tagcgaaagt aacgccgttc aaccctttta ctccttgaaa gttatccggg atatttattc
    14941 cgtcgttttg actgatactt ggcatcttat cgctttcgaa cattcgatta tgcaaagtaa
    15001 atgtaatagg tgattctcta gctgacacag tcggagaacc tataaaaaag accagtagga
    15061 taaaaaagag aacagcaaat atatccacac gtacattttt tgtttttttc atcgctgttc
    15121 acctgctttt ttcttacgat ggataaaata aaagaagcca gaaaaaataa agatcagtcc
    15181 taaaaagaca aagggcagta gacctatccc acctgtcgaa ggaagcaaga gagtcggatt
    15241 gatcgtcaac ttagcggtat ctgttgcgat aatcgtataa ttattgttta cacttccttc
    15301 gcctaaacta atcgttacta tttgtgatcc aatatctgtc cggctgttaa ctgttagggt
    15361 ataatccaat gattcgccta agacaacacc ggtaacgtgg agatttccaa ccgaaatcga
    15421 gtgactttgg gcatcataat taaaggcagc gtcatcgaca gtaatcactg cgttagcttt
    15481 atagatggta taagttcctg atgtgttggc tatatcagta aatgacaact tgggatttgc
    15541 tgctttgact ttgtctattc cgctattcgt tagtttaatt gtatagctgc cagcattaac
    15601 catatttttt gctgattgtg catctgctgt gtaatccata ctgctaagtg ccacttgtac
    15661 tggagtaagc gaactagtga caccctctgc tagcttgaca tggattgacg ggacacctgc
    15721 ttttccatca tatgtcttac tgccactgag ctctaccgca ccgctgattt gcttaatcgt
    15781 atagacatca gatgtctgca cgatagtaaa taaatagttt gttctggcag ctagtttagc
    15841 tagtccgctt tttgtcaatt gccaagacgt ataggttcca atttcagtag gcgcagttac
    15901 ttcaactccc ttttcattca tcgctttgaa atcagttgga ttccatgtga tttgatcaat
    15961 actgagatca ttgtttaaaa gggatgttga ttctgtttta tcattaaagg catatttaac
    16021 gatcggtaca acagaaagac catcatagta cttactgcca tttgcattga ttgatactgt
    16081 tgcatttgtc ttataatata ggatgacttc agaaatctgt tttccatttg cgtcctttac
    16141 gattacattt ccatttgtat ctaaactagc taaaacactc attgctgatt ggttctttgt
    16201 ttctatcgct gaaacagctg taaaggtata tccgttgata gtaggcgtat tagtcgtcag
    16261 gtcttgtgca gcacttccgt aagtaagatt cattatttta gaaggagcaa tcatctgtcc
    16321 aaaatagtct tgatacttaa tagtgattgg tgtttgtttg cctgtatagg tcaccgtatc
    16381 gacgttactt tctagggctg tgaaagaacc gtttgtttgt gcaaaagaat agcccgttac
    16441 tgctgttgga gtgataacca ctttgtcacc cacatggatt ccagataatg tagtcccgta
    16501 cgttccgatt tttgctgctc caccattgac tgtataagaa aaagttcctg tccgattcgc
    16561 attgacctga accgttgctg cttgataggt tggaaaattt gaaacatttc ccttaccatc
    16621 aacgatctgc ccatttttga tcgagtaccc cgtgaatgga atatcatttg ctaactgtat
    16681 accgattgaa aaagtactca tacctcctcc ggcaggaagc cctccccatg ttgagggtgt
    16741 aaaagaataa cttttatccg cattgggtgt aactgaatcg atcgtatttc cagcggtagc
    16801 cacccccata tagatacttt ttgggaatgt gatagtagta ccatttactg tggagccaat
    16861 aaacagatta tggatatctg gacggttatc aataaaagcg attgctttgg ttacgccttg
    16921 taacgcagtt ttatccgcac tcatcgatcc gttaaccgca acaatgactc catctttggc
    16981 atatatcact gtatatccat ctggtatggt atgtccgttg aaattcgcag tggccgcaac
    17041 agtactaaat gtctggcttc tacctgtttc tgaataagct ttctcccctg ctgcttttgc
    17101 tgctgtgatt tctttttctg tcggatcaat cagttgagtc gaggatgtgg ttgaggttgt
    17161 ctcgttgttg ctagactgat tggtgctttc tatggactgt atttcagaat agggtggact
    17221 atttgtctcc tctgtcgttt ggttagcaaa atttgacgtt tctgtataaa cgtttacata
    17281 aatacttgat aagctcccta agaaagtaaa aatcaagatg atcgaaatca taatgggatg
    17341 taagtatttt cttttagata cagctttgag tctagaaaca aaatgttttt gacatatacg
    17401 ttggatttta ttttgagttt tcttaatcat tttcatccct cctctcaata aaaaatcatc
    17461 aaataatcct ttacacgtta ttctaaattt aatttttatt attttattga tgtatagaaa
    17521 gtttggggct ttttttctct ttttattcta aggttatttt agtcttgtcc tttaatacaa
    17581 agattttatt tttaaataaa aaatactctt tttttacgat tattgaaaaa aaaagataaa
    17641 acttgattaa ttgaagtatt gcttaaattt ggaagctatg agggaagaat aaaagagtta
    17701 ggacgggatt atctactatt tttctttgtt ttaaatattt gttatctttg aacataaaag
    17761 agaaatgtgt cgactgcagt gttgtgtccc tcatcacgaa taaacggtgt tcaactagct
    17821 gatcttgtat tcacttaaaa aatggtaaag tacgagttgc tattccccat tttcaatttt
    17881 ctaacgctca ggacaaaata ctgttttcac aacctcattg gaataaaagc atatatattg
    17941 tttcaagaac gaaatcttgt tatcttttta aagggcatct gtccaaaatc taattttagg
    18001 aggtacgttt tggtatttat tcgtacaaat aaaagagaat tatctttatt catgtaacgc
    18061 atccaattga ttttttcatg tacgctcctg gaacgatttt actgacgatt gcttatttaa
    18121 ctgcgaatcg ctcattagct tttatcatag ctatccatat tttgaataac gttcttggct
    18181 ttgtattata gatacagatg acaaaaaaag ttcaagtatg cggtgtagaa ccaatatcgc
    18241 atacttgaac ttttttcaat gagtataaat taaaacttct aattttcaat tcccatcatc
    18301 tgatatgccc gaccgtctga acttcttttg aaaaagccaa atgtgattag ataacgtctt
    18361 tgttcgacat aatcgccact agaaaatacg ttcagcagta tcgaattaac ctctgtttct
    18421 gtataagtca ctccatggtc aaagcgtttc aagacttctt tcaataggat gtatttcttt
    18481 tttgttgaac ttggtacttg ttttactttt ccatcattca tgaatgtgtc taaaactttc
    18541 atcttttctt gctccgtata agtataaacc atcttctttc tccttttgat tctaagaata
    18601 ctccatttat gttagaatat tctggatttt ttattaaagc ggttactctt aagaaagata
    18661 ttatcatagt gctctttttt ttactactac ttataggtag atttattcta atccattatt
    18721 ctcccctacc aataattaaa gaaaaaactg gatcagggtg ttcaaattac atgctaagaa
    18781 aaaagaaccc ttgaatacca agggttcttt ctcagtctga taacaatgat taacgacgga
    18841 tttctttgat acttgtgaaa agtcgttaaa gtattgatat aaaaggattt ttattacctc
    18901 tgactacata ttgactaatt tgttaaaaaa tcgtttttca agaatcctgt aataccagtg
    18961 ctttcaccgt ttttttaact ctctaaagaa ctaaaagcaa tcagaggttt taccttttca
    19021 tttgacgtta agtggcgata aattttcgaa gttgtttggt cagtatggcc taagcgatct
    19081 ttcaagactt cccagctaca gtgttccgct actaagcttg ccattgtatg acgagctaaa
    19141 tgagtatgaa atggcttatt aattcctgag cgattcacgc accgtttgac gtgatcattt
    19201 acatactctc gacgataagg aacaccacgt ttactagaat caagatacac aaacaaatat
    19261 gtttcttcta taataaacct gtaatgttgc ctcatctcac ccaaagcctt aatcaactgt
    19321 tgtagctttt ccataactag aggagttact agaactcgtc tagcagaact aactgtctta
    19381 gtagtttcaa ttcgaaaatc cttactctta cctttaactg ccgtttgctt atagaacaga
    19441 atttcatttc ttttgaaatc tatatctcca ggctgtagag caagcgcctc gctgactcgg
    19501 cagccagtgt aaaatagaac atggaaaagt acagacatcg gtaattcctc atgaacaatg
    19561 ccataattca aaaaagttct caattcatcg acagtaagaa acttgtcctc aatattattt
    19621 atggcttctt ttaaatcagt taccgttaac tgatattttg gcattctcac agacttcatt
    19681 ggattttcac ttatcaaatt ctttctttga caatatttaa aaatcatatt tagaacttga
    19741 ataagtgatt gtaaactatt tttggcatag ccaacatttg ttccattaac gccacattcc
    19801 tttaaggtaa aaagcaattc ttgaaggcac tctggtgtca aatcagacaa ctttttatca
    19861 ccaatccatc gaacaataat ttttaattgt tcctctcgct tatcataggt tatttccttt
    19921 tgttcattta acgaacggta atattggaac cattgctcac ctacaacact aaacttgtca
    19981 ttgcttgcaa caattttttt cttaagcctt tgttgtttct ccatttccag ataagcgagt
    20041 tgcgcctcac gttttgaatt aaagccacgt cttgttgttc gatatgcttg aaagtaccat
    20101 gtgatcctac cagtagaact gatttgcttc ttgaatcgat ctgttttttc catttattga
    20161 ttcctcctat tttgaaggaa cccaacaagc agaaaccctt tggaaatctt tctatctatg
    20221 tcatcattgt accgcatctt agaaagaaaa tgtaacttat aaagatcgaa gtagtcgcaa
    20281 tttttctcga tagtcattcg aatcactctt tctcatccat tctaaaacat catcacgaaa
    20341 atagtgtcct cgaatcccgt accaacaggg aggaaactca ccaagtttta ctaaacggtt
    20401 cagtgtacta tcacttatct gaaatagtcg ctttaaatca gtatttgtta ataccagagg
    20461 taaatgactg actgcaagca atttttccgt gtaatcttcc agtttttttt gtaaaattga
    20521 atagaactct atttccagag aattaacatt tgttttaact tccaactcca tcacccttct
    20581 ctctcaaaat caaaacgacc accacggtac cccttaaaat tgtaaaaaaa cactccagta
    20641 ctccatcaaa acggactaga aaagaggaat ttttaatatg aaacaaggaa ttgcagacat
    20701 aaaaataatt aaagaaattc ttgaaaaatc tacggctaat gcaatagcat tcggaacagg
    20761 aatcaacttg agtacagtaa aaaaacttaa aagtggagag agagctgaag aaaaattaaa
    20821 tcttgccgat gctattaaaa tcacagaatt tggcatgaaa aatatgccaa ccaaaatcga
    20881 aatatggaaa tagtagtttt tctgatctat cagctgtttt gccaaagcac ataggaatct
    20941 cacctccccc cagtaatggc gggccgattt ggttacggaa gtatcattat cgtagtcgcg
    21001 attctcatat taaaatttgt cgcttaaaag ctaaccttgt catggcgtaa ctagagaatc
    21061 aaaatctaca tgtactgata gatttgctat tcatttgtca aagagcgcta ggctattttc
    21121 agcctatgga aatcctttat tttgacccga taaaaaactt ccatagaatg aaaaggaaag
    21181 ggaaaaaata ctttaacgag ttgtatcaaa ttcaagtatc ttctcaatca attttgtttc
    21241 cagttgtcta cgcatatatt catctacata cataaccatt cctttttctt cttcataaac
    21301 tggtttcatg gctaaccgtg aaatataatt ttgatatttt gacagaacga tggacatggc
    21361 aattgaatca ccagaagctg cggctttgat tgtcgttagt ggtatgaatg gtatatatcg
    21421 tttattttgc ttcatatttg acacccaaat actttcctag ctcttccaaa gccatttgtc
    21481 gttggtacca aacactgccg agacttttcc caataatatc gccaatttca cgatcattaa
    21541 gaccgatgaa gaaggacata aaaatgattt cttgtctttg actaggtaat gctgcaatcg
    21601 catttgccaa ctcctcattg gaaataaaga ttttcatacc aaggacaata aaagtaccac
    21661 tactattcaa atttggttcc aaataataga actctgtacc taaccctttt tgttccaata
    21721 tttccattga tatttgccgt tggcgaaatc tagcgtactt cttttgaata tttaacgcct
    21781 cattgcagac tactttctta caaaaactgt caaacgtatg ttgaatgtgg gtttcctctg
    21841 agtcgcccat aatattctcc ccctcaaaaa attcattcaa ctcgttttac ttctatccct
    21901 ttccattatt actacaatct agga
//
LOCUS       DADLIO010000048        20664 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.048, whole genome shotgun sequence.
ACCESSION   DADLIO010000048 DADLIO010000000
VERSION     DADLIO010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20664
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.048"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            168..362
                     /locus_tag="JOX41_001900"
     CDS             168..362
                     /locus_tag="JOX41_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449642.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            631..930
                     /locus_tag="JOX41_001901"
     CDS             631..930
                     /locus_tag="JOX41_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449643.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(1027..1461)
                     /locus_tag="JOX41_001902"
     CDS             complement(1027..1461)
                     /locus_tag="JOX41_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAY6449644.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1693..2403)
                     /locus_tag="JOX41_001903"
     CDS             complement(1693..2403)
                     /locus_tag="JOX41_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAY6449645.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2393..3253)
                     /locus_tag="JOX41_001904"
     CDS             complement(2393..3253)
                     /locus_tag="JOX41_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HAY6449646.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3258..3896)
                     /locus_tag="JOX41_001905"
     CDS             complement(3258..3896)
                     /locus_tag="JOX41_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HAY6449647.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3911..4210)
                     /locus_tag="JOX41_001906"
     CDS             complement(3911..4210)
                     /locus_tag="JOX41_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAY6449648.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4253..5737)
                     /locus_tag="JOX41_001907"
     CDS             complement(4253..5737)
                     /locus_tag="JOX41_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HAY6449649.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGVLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5757..6218)
                     /locus_tag="JOX41_001908"
     CDS             complement(5757..6218)
                     /locus_tag="JOX41_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAY6449650.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="JOX41_001909"
     CDS             complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="JOX41_001909"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HAY6449651.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7521..8291
                     /locus_tag="JOX41_001910"
     CDS             7521..8291
                     /locus_tag="JOX41_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAY6449652.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8564..9391)
                     /locus_tag="JOX41_001911"
     CDS             complement(8564..9391)
                     /locus_tag="JOX41_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAY6449653.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9959..11194
                     /locus_tag="JOX41_001912"
     CDS             9959..11194
                     /locus_tag="JOX41_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HAY6449654.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12193..12453)
                     /locus_tag="JOX41_001913"
     CDS             complement(12193..12453)
                     /locus_tag="JOX41_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HAY6449655.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12480..13781)
                     /locus_tag="JOX41_001914"
     CDS             complement(12480..13781)
                     /locus_tag="JOX41_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAY6449656.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14073..14531)
                     /locus_tag="JOX41_001915"
     CDS             complement(14073..14531)
                     /locus_tag="JOX41_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAY6449657.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14544..15869)
                     /locus_tag="JOX41_001916"
     CDS             complement(14544..15869)
                     /locus_tag="JOX41_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005227470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HAY6449658.1"
                     /translation="MKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDEER
                     NMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKIPL
                     KHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVRRK
                     YPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREIMP
                     EIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVVEH
                     TDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLNDDR
                     RRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAVEK
                     LLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15886..17298)
                     /locus_tag="JOX41_001917"
     CDS             complement(15886..17298)
                     /locus_tag="JOX41_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAY6449659.1"
                     /translation="MNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADDMLNIPVIGAA
                     GNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMDPEVNMGIFGG
                     IISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLGFIWPLIQIGI
                     DNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSPSKEVFRGEMT
                     RFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMGSGAGTSFIAN
                     ITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVDYLINFRIATN
                     AILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEETELGLASKNYE
                     YMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISGIIKPTEKNYQ
                     IIIGLEVTYVMAEFNKLLEE"
     gene            complement(17315..18079)
                     /locus_tag="JOX41_001918"
     CDS             complement(17315..18079)
                     /locus_tag="JOX41_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HAY6449660.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(18183..19058)
                     /locus_tag="JOX41_001919"
     CDS             complement(18183..19058)
                     /locus_tag="JOX41_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAY6449661.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(19313..19397)
                     /locus_tag="JOX41_001920"
     tRNA            complement(19313..19397)
                     /locus_tag="JOX41_001920"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19361..19363),aa:Leu,seq:caa)
     gene            complement(19415..19486)
                     /locus_tag="JOX41_001921"
     tRNA            complement(19415..19486)
                     /locus_tag="JOX41_001921"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19452..19454),aa:Gln,seq:ttg)
     gene            complement(19496..19568)
                     /locus_tag="JOX41_001922"
     tRNA            complement(19496..19568)
                     /locus_tag="JOX41_001922"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19533..19535),aa:His,seq:gtg)
     gene            complement(19630..19714)
                     /locus_tag="JOX41_001923"
     tRNA            complement(19630..19714)
                     /locus_tag="JOX41_001923"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19678..19680),aa:Leu,seq:caa)
     gene            complement(19735..19805)
                     /locus_tag="JOX41_001924"
     tRNA            complement(19735..19805)
                     /locus_tag="JOX41_001924"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19771..19773),aa:Cys,seq:gca)
     gene            complement(19851..19922)
                     /locus_tag="JOX41_001925"
     tRNA            complement(19851..19922)
                     /locus_tag="JOX41_001925"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19888..19890),aa:Gln,seq:ttg)
     gene            complement(19934..20006)
                     /locus_tag="JOX41_001926"
     tRNA            complement(19934..20006)
                     /locus_tag="JOX41_001926"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19971..19973),aa:His,seq:gtg)
     gene            complement(20009..20082)
                     /locus_tag="JOX41_001927"
     tRNA            complement(20009..20082)
                     /locus_tag="JOX41_001927"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20048..20050),aa:Trp,seq:cca)
     gene            complement(20089..20169)
                     /locus_tag="JOX41_001928"
     tRNA            complement(20089..20169)
                     /locus_tag="JOX41_001928"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20133..20135),aa:Tyr,seq:gta)
     gene            complement(20171..20246)
                     /locus_tag="JOX41_001929"
     tRNA            complement(20171..20246)
                     /locus_tag="JOX41_001929"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20211..20213),aa:Phe,seq:gaa)
     gene            complement(20282..20354)
                     /locus_tag="JOX41_001930"
     tRNA            complement(20282..20354)
                     /locus_tag="JOX41_001930"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20319..20321),aa:Asp,seq:gtc)
     gene            complement(20364..20436)
                     /locus_tag="JOX41_001931"
     tRNA            complement(20364..20436)
                     /locus_tag="JOX41_001931"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20401..20403),aa:Val,seq:tac)
     gene            complement(20452..20523)
                     /locus_tag="JOX41_001932"
     tRNA            complement(20452..20523)
                     /locus_tag="JOX41_001932"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20488..20490),aa:Glu,seq:ttc)
     gene            complement(20538..20627)
                     /locus_tag="JOX41_001933"
     tRNA            complement(20538..20627)
                     /locus_tag="JOX41_001933"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20591..20593),aa:Ser,seq:gga)
BASE COUNT         6532 a         4320 c         3273 g         6539 t
ORIGIN      
        1 taagaacaat agccttttat tatatatatt attcaaatta gttatatcga gtgaaaaaaa
       61 ctttcaaatt gattcttttt atttatcata aagatataga tacataatca ttttcactta
      121 catatatttg aatattaact aaaaacagca agaaagaaga ggatcaaatg tattatgtag
      181 aagtaaaaac aaaaggcgtc aaaaacaaac aatatgtgaa aggtatcagt aacgaatatc
      241 ctttacttgg ttcatggaaa gaagctgctc ctttttccaa accatgtgcc ataaaaataa
      301 agaacgagct agaaaaagaa ctgacttgtg gtaaagctgt tgtagatatc atcgaaaagt
      361 aaatccaatg tatagaaagg aagatcacac atgaaaagcg acgtacaaat tgctaagatt
      421 atagaattag aagaagaaga cgcagtgttg acaattgaaa aaaaataaat gtttgtatac
      481 catatgatta tttcaatatg tatcctggaa ttggagatct cgtagagcta tatcaagatg
      541 aatcaaatat acttgtcatt catcatgaaa tatagagact tataaaattg tttattttta
      601 taatgtatca gtatagaaag gaaataaaac atggattata ctgttgaatt tgacagtgaa
      661 ctacttaagc aatttccaca agaagaacat ttcatgtata aagaagcaat ttcccacaaa
      721 gtgacagagt atttggagca taattttttt cgtataaagc cagtgcgtac tcgttcggca
      781 aaaggaatat acgagatgaa agtcaaaatt aataaaaaaa attatcgcat agcatttgct
      841 ttaaaaaaaa atcatgtgtt cattttttat attagttcga atttgcaaaa aattgtattt
      901 gataaagagg tgagtaaaaa aataaaatag ctgagcattg gaggatagat tgagtgatac
      961 taagtctatc ctcttgtttt tctaaagaac taagctagaa ttttttcttt tgtacgttat
     1021 tatatgttat ttgtcattac caaaaagcac cttttttctt ctagtatcta tgacataaga
     1081 aataccaccc atttccttta cttgaacaaa tcctactgat tcataaaatt tttttgtttt
     1141 ctcagtatca tctgtcaata attcgatttg gactggtcca taactagtga tcttctccaa
     1201 agcttcattc aaaagcactt tgcctattcc ttggcgctga tacctcggat gaatgaggat
     1261 atcttgaata aatgcgatcg tcgcaaaatc agtgatccaa cgaacgattc cgataatctt
     1321 cccttcccca ttacgcttta tcagagattc agattgttca aatgctctag ctaaccttgc
     1381 agtgtctttt gtgtaattcg tccaaccaac gctcttatat aattcagaaa tctcatcgat
     1441 cataagggaa tcaatattca tttttttctt cctttcttat acaattctcc ctctaataat
     1501 acagttcttt gactatttaa tctatcacat ataactctcc tgtaaagatt ctctcgattc
     1561 cttaaaattc ctctttcctt ttagaatgca tactttttga taaataaaaa ggttgtgata
     1621 aattttcttc acaacctctg tttctctcta tcaagtgtta tcttttaatt ttctaccctt
     1681 accctagcat ctctattgcc cgtagtatgc atactttcca tgtttgcgaa aataatgttt
     1741 atctagtaaa tattgcggga tttcacatat attggggttg atcagctcgt tttctttggc
     1801 catcagacaa atttcatcta agatcaaact gttttctact gctttcatag gtgaatcccc
     1861 ccatgtgaac ggtccatgtc catagacaag tactccaggg acttcgtttg gatctaattt
     1921 tctttcctta aacgtctcga caatcacatt ccctgtatga acttcgtaag cttctcttac
     1981 ttcttctttc gttaattggc gtgtacaagg aaccttacca taaaaagcat cagcatgagt
     2041 cgtgccataa gctggcaaat cgcgtcctgc ttgcgcccac atgacggagt gcgtggaatg
     2101 agtatgagta atagcagtta tatcttcaaa agtttgatac aaaacaacat gtgtggggag
     2161 atctgaagat ggttttaagc tatcttcttc tattatattt cccgacaaat ctgttaccac
     2221 catttgatct gcttgcatgc attcatatct gacaccgctt ggcttaatga cgatgactcc
     2281 tagctcacgg tccacttcac tcacattgcc ccaagtcaat ttgactaatc cgtatcgcgg
     2341 caatgccaga tttgcttcaa ggacacgttg cttcattgct gcaatttttt cttcacaaga
     2401 catcatagcc agcctccttc aatttagaac ttaagtagtc ttttgcctgc tggatttctc
     2461 ttcgaaagtc ttggcttttt tcactccaca tttcaatcag aaatgttcca tcataatcta
     2521 gacgtttcaa atgtcttaat aatccaagaa aatcaacaca accgctacca aaaggaacat
     2581 cacgaaactg gcctgaatat tcttttgtta cagggtaagt atcttttaag tggatagcag
     2641 tgatataatc gatccctttc tcaagttctc gagccggatt attttccggc catgcggaca
     2701 aattgcctag gtctggatat acttgtagaa aaggtgaatg aatctgttct ttgatttcta
     2761 aaaattttga aatggagttc ataaatggat catccatgat ttccacggaa agaatgatgc
     2821 catatttaga agcttccttt acgctttctt ttattccttc gataaagtct tctctggaat
     2881 tcattgattt ctcttcataa taaacatcgt atccagctat ttggattact ttgacgctta
     2941 gattatgcgc caaatggatt gcttttttca ttagttgttt cgctgctttt ttcttttctg
     3001 gatcagcaga accaaacgga aatcgccgat gcgcacttaa acaaatcgaa tggatacgta
     3061 caccggagct gaacatctct tctctcagct cagctatctt ttcttcagac caatctaatc
     3121 gtgctaaccg ctcatccgtc tcatcaatcg acatctcgat aaaatcgaag tccatttctt
     3181 ttacaaggga aaaacgttct ttccatgaaa tatctttggg taacgctttt tcataaatcc
     3241 caatttgagc catttcctta cccccagata cgaatgatct catctttgaa gttttgtgcg
     3301 gccttcatcg gatcatttgc tgctgtaata ccacgaccag tgataaaggt atacacatcg
     3361 atcccttcaa ataagtgtaa tgtgtgtgga tttaatccac cagttacaga aacattaaag
     3421 cctagttcaa tcagtttttt gatcttcgat aaatcttttt caccccaagt ttcaccagat
     3481 aacagcgcat cacggctttg atggtagatt acctgccgga taccgatgtt atgccaatcc
     3541 atggcttgtt caaaagtcca attgccgtag agttctactt gcaattcacc tatttctttt
     3601 tgtgctgcct ccatagttgg aatcgttgca caacaaatga ctgtcatcca gtctgctcct
     3661 gcttttgcaa cattactcgc cactgttcct ccagcgtctg cacatttcgt atcagcgact
     3721 agttttttat ctgggaacat actgcgaata cagcgaatcg ctttttgtcc ttcctgtaag
     3781 caaagaattg tgcccacttc aataatatct actacatcac caactttcat aacatctcct
     3841 aatgcatgtt ctaagtcatt gtgatctaac gcaatttgca aattcggcct gctcatctta
     3901 gttccttcct ttacttgttt ttttggtacc actttgtttc agcaaatttt tcactgattt
     3961 ctttgactga catcacattt ttgataccga taactgtaac tccttttttc tctgcctgag
     4021 taaacatatt caaaaaattg actggcgtaa aaactacatc gtattggcca gctgaacttt
     4081 ttccctctga aatggcacaa tgatggattt tggtaattgg tacgtttagt tctttcattg
     4141 ctttttccac acttctcatc atcatcaagc ttgttcctga tccatttgca cacgatacta
     4201 aaattctcat cttaatccct ccattatgag tgttgtctaa tcagattttc ttttatactc
     4261 tctgcttttc tgcatatgtg tcatagtctt ctacaatcaa aaaataacca tcaggatttt
     4321 tccgatattg taactgcgga atagccaata aaccaatgac aactacggca attccagcat
     4381 aacctaggac tttcatgatt actgtaaaca atggccaagc tgttgcccag tcgaacatcc
     4441 cgatataacc accgtatgtt gacatcccaa tccatgtagc gaataatgct gaaccgccta
     4501 cttgtatgat tcctgaaaga aacgggaaca ggcaagcggc tttgaatcca cctcggttat
     4561 tggcataaac tgctataacg gcattatcaa agaacaacgg aatgaaaccg gctatgacga
     4621 tcgttggtga tttcaataaa atcagtaaac caatcatcaa aaactgtccc aaagcaccaa
     4681 acaagacccc aatcgttacc gcatttggcg aaccaaagcc aaaagtagca gctacgtcaa
     4741 ttcctggaac agctcctggt aaaatcgtgt ttgagattcc ttggaaagat tgagttagtt
     4801 catcgacgaa tgtccgaaca cctaattgca agatcgccag atataccgca aaatttaaag
     4861 aagtcgtcat aatgtagaat aagaaactct gcccttcttg catgaattgc gcttgaatca
     4921 aataatcttt gcctagtaca atcagaatga tcccaaagaa aaatagcatg agtaacgaag
     4981 tagcaaccat attctcattg aaaatcgaca agaatcctgg taatttgata tcttcaattt
     5041 ttttgtcttg cttgattgat ctatttttct tttcatcccg ctttttcatc cactcagcta
     5101 attttgcaaa tataaagatt ccgaacattt gctgatgtgc cactgcaaat ccggcacctt
     5161 ctgtcaattc ctgcgtgatt cctactgtta agttagaagc tactgtccaa taacaaccta
     5221 aaatcagtcc cataaaaatc aatgcttgta tcctacctag atcaggaaag caaaacagta
     5281 aaatccaaaa agcggtagct gcttgttgaa cctgaacgtt tccggtagtg aaaacggaac
     5341 gcagtttcgt atatttctga aaacggacta ataagatatt taaaacaaat gcaatcagta
     5401 ataaaatcat cacatctcca aaggtacggc caaatgtctc cattaatcca gcatccacag
     5461 cattttgtcc aaaataagga tctgtaacca tggcatccaa attgaaccgt tcctttagtc
     5521 caaccaagat tggccgaaaa ttattgacca aaccaccaga gccaacagtc aaaataaagt
     5581 aaccgaccgt tgcctttaag aatccagcga tgcattcatg aagcgggcgt ttcagcaaaa
     5641 tatagcctaa taacacgata aaaccaatca ggtatgctgg ctgcgtcaag atatttgttg
     5701 caaaatacgt ccaaatgctt aacaaaaatt cccccatctt ttttctcctc tatcaattaa
     5761 ttatattctg ccatcacaac ttggtaatca tcgatggagt tcgtagagat gagacgctca
     5821 accaatccat ctgtcattaa taattcggat aatttttgga tattttctag atgttcttct
     5881 ggatcttttg ctgcgagtgt aaaaaacaaa ctagccgttt tctcctcatt ctccccttca
     5941 ctttcaaaac ggattggctg tttcaacttg gtaaatgaaa tagctgttcc aaaaacacca
     6001 tcactttttt ctgaagaatg cggcattgct acttgaggtg cgatcacaat ataaggaccg
     6061 tatttttcta cacaatggat gatctcctcc acatacgttt catcaataat ttccttatcg
     6121 atcaatacaa gacagctttc ggcgatagct tcacgccaat ccgtgatttc tttatctggg
     6181 taatgaatca attgatggtc aaaaaagtat ttcagcaaga aactcccctt ctttcttata
     6241 aaaacgacgg aaacggtgta tcattttcaa tcgagaagac atcttcaaat cctcgataaa
     6301 aattaaactc aagatcatct ttgtttgtcg gatagatgaa tttcccgcct acttgccaga
     6361 tataaggttt aaatccatac ttcaggcgat cctttttgaa tttccaaatt tcagtgatct
     6421 cttttggatc agccataaaa ttagaccaaa tatcgtagtg gacaggaatc actacttttg
     6481 cattcaatga ctccgccatg cgcagcatat caacagaagt aactttgtct gttatccctc
     6541 gtgggttttc accataggcc cctaaacaga catcgatttt gtgttcatta ccatgtttgg
     6601 caaataaatt ggagtaatgt gaatctcctg catgataaag attccctcct gatgtttcga
     6661 ataaatagtt tactgcaatt tgatccatct cctgaggcat ttttcctttt aatacctctt
     6721 ctggatcttc acaagtgacc aacgctgtcc gatcaaacgc ttctaaagct actacattga
     6781 tgtctttgat tttgactgca tcacctggct ttactgtaat cgttttttct tcaggaattc
     6841 cccatttttg ccacgtgcga accacttctt ttggcccaat gaatgttgct tcaggacaat
     6901 tttgatgaac tgctgcggct gtatggatat ctagatgatc ggaatggata tgtgtaacga
     6961 ttaaagcgtc tacatttttt atcgcaaaag gatcgattac gaaaggctga gtacgtaaat
     7021 taggctgcat attttgaacg ccactcatac gcatcatctg atggcctttt ttcatcatgc
     7081 cattcccatg actacgtttt cccgtcccac accatagatc acataaaata ttcgttcctt
     7141 catgactttt cagccaaatt cccgtacagc ccagccacca catagcaaaa gttccaggat
     7201 ccactacttc tgtttcgatt tcttcattca agtatgtgcc ccactcagga aatgtttcta
     7261 ctaaccactt ttcttttgtt acttcattga cagttttact catttgcttg ctccccccat
     7321 atcgttgttc caacttacaa gtaaatatta atgtgtatca gcatccatga aaaccctttt
     7381 atatgaccgt ttgtttttta tatgattttc tttcagtaat caatgattgt ttcagtataa
     7441 taaagacaga tatgaatgtt taaatgaaca actagtcaaa taaatccatg gatcaagatg
     7501 tccctcagga ggcaaaagtc atgaaaaact cacttgtcaa tattgaaaaa cgtcaaaaag
     7561 aaattttgga actgcttcag cagactgaac aactatcaac tttcgaatta gctgaatccc
     7621 ttgatgtatc tattagtacg atacgaagag atttaaattt attagaagaa aaaaacgaga
     7681 tcatacgcaa ttacggttat tgttcttata attacaaaaa ccagactgat tttgatcaat
     7741 ctggtcctga aaggattaaa caagcgattg ccagagaagc tagtaaatac attaacgatt
     7801 atgatacgct gtttatcaat tctagctcga ctgcgttgaa aacactggat tttcttcaat
     7861 ctaaccattt gacagtcatt acaaacaacg tgaaaatcaa ttactctccg cacaaagata
     7921 attgtagtta tattttaact ggtggagaga tgcgctttcc aaaagaagca ctagtgggcg
     7981 acatcgcatt aaatacgatt tcttcagtca atgcagacat ttgtatcatt ggctgtagcg
     8041 gagtcgatgt agtacatggg gtcacaacaa agatattaaa tgaatcaacg atcaacgaaa
     8101 tgatggtcaa caagacaatc aaatgtaaga ttttagtcgc tgatcatcga aaaatcggac
     8161 tgacatcaaa gttcaagatt gctgatattt cagtctttga ttatttgatc actgataaat
     8221 tttgttctga aaaagtatta gaggagatca gaaatacggg gataaaaacc attcaagtag
     8281 attcatttta agaaccagga cgtaaatatg taaataggat tatcaaaaaa atgaataaca
     8341 aatttatcga taaatgaaaa acacgctacg ctcaaattga taaaggaatc ccaagatgta
     8401 tccatccaat cgataccatc ataatctatt gcttctttta taaccgttat atgttgccta
     8461 aataggaatc aaacaatatc gaaaaaagga ggtatgacaa aagtcacacc tccttttttc
     8521 gaataaacgg tattcaaatc agaacactga tttcacaacc actttatttc aggtcgtttt
     8581 caatcacctt taccgcgtaa tcatttccgt tgaaacgcgc tatttttttt gcgtccatat
     8641 atctttctaa ataatcatct tctcctaatt gcttatggca agaagcaatt tcataaagca
     8701 agtattccaa tgcataagtc gatttatgtt tcttattata ctcaataccc ttctcacata
     8761 attggattgc tttatcataa tcctcgattt tacggtaata ggtggcgata tcataatata
     8821 caatgcagac catcagatta tcaaaatcag tctcactcaa tattttaagt gtacgctcca
     8881 cataaacttt cgcaaaatct aattctcctt ttgacaagta gatcattgcc acgtttgcag
     8941 ctgcttgtaa gtgatggata tctgtttcgg tcgtttgttc caacacttga ttaaaataaa
     9001 ataatgctgc atctggtttt ttcgcataaa gatgatcaag cagtccttga taaaataaaa
     9061 tttgatttaa aagatcagaa ttacttactt tttcctgatc gatcgtttgt aaaattttat
     9121 aagattcttg gtattttgat acagaattca atgattgaat ctcatttatt tttttcctga
     9181 ttttgtcttc ttctgtttct actaatatat cggagatctc gacattcagc tttttgcaaa
     9241 gcgcacttaa gatattgatg cctggcgaca tattcttgtt ttcgatattg ctgacagttg
     9301 cttgttcaca aatgccttct gctaattgta cttgtgttaa cccctttttc tttcggtatt
     9361 cttttagtaa tgctccatct actttaatca aaacaatttc cttcccttta aaaaattatt
     9421 tctcctttat atcatacaca aaaaaaagtt ctaaacaacc aaaaatgttt agaacagaat
     9481 aaaaatttta attttaaaat aatattcaaa ttaaacaact ggcgtatctg ctccttgatt
     9541 tctttttgtg ttatctgaat aattatcgtt tacagttata acacatagtg aaaattgtca
     9601 tggcgagaaa gtctaagaat atttttaaac ataactattt ctttcttacg tgtgtataat
     9661 gacgacagca cacctatcaa ttaatataat tattttattt ttttatgttc tcatgtttat
     9721 ttttaatgac acaacttctc gtatttatct ggcacaacat ataaatcgat caaaaaattg
     9781 ttgcgtgttt ttttgaaaat tggagtttca acttgattac aaaatttaaa tttagaagtt
     9841 gtgaaaacag cgagagacag tttaatattc aaaatataca taggctactc gaacgctgtg
     9901 ttttttagta tactagtaag aaacgaaggg atagactcat tccaataagg aggatttcat
     9961 gaagacaatt ctttttgctc ctgcagtatt caatttagct gagacaacac gaatgattga
    10021 ggttgccaaa gctatgaaag accgttatta ctgtgtattc tttggctttt ctaaaacttt
    10081 tgctcctttg atcacagaaa gtggctttga gtatcattta ctagcgccga tccttacgaa
    10141 aaaacaagaa gaacaaatca taaaatttga ccagttgcgt acacttaaaa acccttttac
    10201 caaagaaatg gttgcctctc gtatcactag tgaacagagt ctgattgcta agtttgagcc
    10261 tcgactgatt gtgacaggtt cgaatgtgac aattttttta tcggcccgca ataaaaagat
    10321 tcctttagta tatgttaaac cctatgcttt gagtgaacct ttttttcaat cagagcatgc
    10381 gctgatgccc cacgagttac gtttcttcgg ccctttaagc aatccccttt ggcactggac
    10441 aaaaaagcgt atagtaaata cccgatggat ccccaatgcc ttcaaacacg ctgcacaaaa
    10501 agaaatgctt cctttaccaa aaacaagttt acaaatgatg gatgctgatc taaatctcat
    10561 cacaacgcct aaactatttt tggaagaaga acagctgccg gaaaattatc gaatcgttgg
    10621 tccaattttt gctaagctca gtacttcctt gcctgaagaa gtgctaactt ttatacagcg
    10681 aaagcaacaa gaaagaaaac gtattatcta tttcgcaatg ggtagttcag gcaatccgcg
    10741 tatgttacgc aaaattttgt tcttcttaca aaaacaaccg gatctagcgg ttattgcacc
    10801 tattgactat ctgcttgatg acattcaatc tgactcagaa gatcttttaa taacagaata
    10861 tctgtctagt catcttttgc atgaattcat tgatttttct tttatccacg gcggggaagg
    10921 gaccgtccaa actgcctgtg aatccggcaa accgtttatc ggtgtgggga tgcaatttga
    10981 gcaaagctgt aatattgact attgtgtaaa atacggaaac gcaatcgccc tcacaaaacc
    11041 agtgactgaa agaaaactgc agattgctct gcgcgaagtt tcttcaccca agattcgtca
    11101 gcaggcacgc acgctgcaag ccgtttttcc aataaatggt ccacaacaag caattcaaga
    11161 aatcgaaacc ttcctgagca accacccaat atagtttcaa gtagaaaaag cttttttaat
    11221 agagactcat cagtaatttc gctattcgag acccagacag tgaaaataca aaaaaagtaa
    11281 atagtggatt gaaaagttag agttacttaa attacggtgt ctaaaaaaca caaaatcatc
    11341 cttaaaataa aagatctgac gctatccaaa tgagcatagg tagcgtctgc catttattct
    11401 tagtcaaatt ctttgacacc tttctctggt tggatcatct caacgtttct tcaaaagaaa
    11461 gaccataata attaggcaaa tacattttct taaaatgtgt catatagatc tagaagcatc
    11521 gctttgtaga gatttgtgcc gctagtcccc tcaacaatta ctaaatcaaa tgtaggattt
    11581 accactttat ctttgataat caacctccct cttctgttga gacaatgatc tcgcaatccg
    11641 atgcatactc ctatataaac tgccagcaat ccccacatat tgagtagatc atgtcagaat
    11701 gttctatgtc gtcagcaacg atacactaaa agtcacgttc accatgactg attgctattc
    11761 ccagcacaat tatttctata cacgtttcat gatttgaata aacactcaca tcatacatat
    11821 taccattcat acaccatact gcagccccta ctatatggtt gtaagctccc aaatctatat
    11881 ttgacttgat cactttggta gtagatctac taattctaaa tccattgctg ataaaatttc
    11941 cattttttcc tccttctttc tgccaaaaca gttaaaacaa taataatctt tatgtaaaaa
    12001 agggctgtga caaaagcctt gtcacagtcc catattccga ataaacggtg gtcaaaagct
    12061 tgcatctgcg gtaataagtt caaccaaacg aaaaataagc caacatttca caaaaattta
    12121 agaagcaatt ttcgtaaatt tcttcttatt tcttgaagct aaccacttct gttacaacca
    12181 cttttagaac atttaaagct tcgatgtgac aaaccatcta tgctgctcga tcataaaatt
    12241 gatagcaaaa attccacaaa gtacatatgt cccccatgaa aacaaaacat tcatatgcgg
    12301 tacaatgatc tttggaagaa tcacgatcaa aaatgatgcc agtgcccaaa tccatcgatt
    12361 gatttgaata tgatatgtag ctagcatatt caatataagg tgactagccg ttaataaaaa
    12421 gataaaaaca aaaaataaaa tcagccaata cattgtttcc caccttctaa aaaccaaact
    12481 tagacagtct ggacttcgtt ttctccacga ctttgttcat ctgacagcat ctttttatca
    12541 taagctttta caaatggata atagataata aatgctatca atgtgttgat catgatcaag
    12601 ataacaacac gccagtcatt tcctgctgaa agataaccgc cgattggagc tggtaatgtc
    12661 catgttggca aaacagtaaa tctattgacc atttctaatt tgactgcaaa ataactgata
    12721 atagtcaaaa ctaaaggaac taagttgaac gggatgaaca tgtaaggatt caacatcata
    12781 ggagctccaa aaattatggg ctcattgata ttgaagatac caggaataat agaaaaacga
    12841 ccaacctctt tcaagaattt tgatttacag aagaatataa acaaaacaga taccacgatc
    12901 gttgctcctg caccaccaat tgttaccgtc cattgataaa actgttcagg agcgatatag
    12961 ggtaattggg tggcagctgt accatctgcc aatgcctttg cattctcatc caacatgatc
    13021 agccacattg gacgaacaac agcccctaca atactcatgc catggatacc aaatgaccac
    13081 aacaaatgga tcaaaaacat tggtagtaaa acaccaagca aattattccc taaaatattg
    13141 gttaaaggct cgaataacga taataaggca gcgtttacat caaagcccgc gacgcttcga
    13201 atcagccaag taattgttaa aatgactgca cctggaatca atgcctcaaa actacgggca
    13261 acagcaggtg gcacttgttc tggcattttg atagtaatat ttcgattttt aaagaaacga
    13321 tatacttcca ctgcaaaaat catagataag atccccgcaa acatcccaga tgctcccaaa
    13381 gaactcatag gtaagaccca gccaagaggt gcctcttcag gagttaaaac gtttacagga
    13441 acttgtaaca taaagaacgt tcctaaagat aatataccac ctgtcacact atctaatcca
    13501 tatgatttag ctagatccga acccataaca aaagttgcat aaatagccat caatcccatc
    13561 gtcatcctaa agggtaaaac aatcgttgcc gaataagggg caataaattc attccatcca
    13621 ggaaacggta aattgataaa gaccataaaa aatgtcccaa tcaaaatcaa tgacaatgtt
    13681 gaaacaaccc cattacgaat tgctaataaa tgacgctgtg taccaatttt tgccattggt
    13741 gggacaagtt tctcttcgac ccatttcatc agcttttcca ctaaaaccac tccttttcaa
    13801 taaaatatga accattcatt gcatgacaac gcaaagaatg ttcataacta attatataat
    13861 taagaaattt tatttcaata tattctctta aataatcaaa tttattttta agaatcctga
    13921 aaataagttt tctaaatcat aggagcaaca aaaaaattcg ataattaaca aaaatcaaaa
    13981 tgattaaatc tagtgattga aacatatcat ttcaaaaaaa ttttgtaaat tcacccataa
    14041 atatcaccct atttaacttt tttcatcgta cactaaaatt caaaacaact atctttaatc
    14101 tttacttctt ggttttgttt taataaattt ccttcaaaaa tgcctggaga aactacaatg
    14161 atcaccgtat ctttttgtgc ttgctccaac ttcttcaaat ctataatagc taacagtgtc
    14221 ccttctttta cctcctggtt actttcaacc cgtatctgaa acggacttcc ttcgagttca
    14281 actgtatcta aacccatatg gatcagtatt tttctgccag attcactttc gatcgttatg
    14341 gcatgtcggg taggaaatat attatcgatt attcctttaa ctggcgcatg gatatatcca
    14401 tcatgattcg ttatagcgta tccaactcct atcatttttg aagaaaagac ctcgtctttt
    14461 actgctgtta atggaataat ttgaccacta gctacagctt ttagaatgtt tcttgtttta
    14521 aagaaatgca ctttttatca cctctacttt aatgctggcc aatatttttt gtttactttg
    14581 atcatttcat ctagtatttt ttttgcgact ctggcatttg gtacggtttg attcaatgta
    14641 aatgcttgta aagctttttg ataagaacct tcaaagtaag catctactag taacttctct
    14701 actgcaactt gtgcctccat caatccttta tgaaaatcac tgattggttt tcttagtgta
    14761 attggctcca caccagttgc accaacatat gccggtattt caacaactgc atctgaccgt
    14821 agattcggaa tcgccccttg attaggaacg attagcataa agcgacgacg atcatcattc
    14881 aacaaggaaa tagctatatc gacgatatat tgtccatgct ccccaaaatt aaagttcaat
    14941 acttcttcca caataccgcg gcgtatttta tcagccattt ctttggtatt tttctctcgt
    15001 ccatccatga ccatattagc acgtgtatac tctttgtcag tatgctcaac gaccatatca
    15061 ggatataagt aatactctaa gtaattattc gggatattac ttggaaaatt tttcgtgatg
    15121 actgacatca tttgaaaggt tttttgccaa gttttatctc ctatattaaa atcggcgact
    15181 tgcatttctt ttgttattag tttttcaata atctctggca taatttctcg ttgcaattct
    15241 ttatcataaa tcgatgtata ccagccaaag tggtttaaac cataatacgt aacgatccaa
    15301 ttcttacgat cataaccgta attcactgca atcgtttctt caattgaaat agtcatatca
    15361 caggcattaa tcatttttac attcggatat ttacgacgaa cagcttcaga aacgatcgac
    15421 tctggatttg tataattcaa aatccatgct ttgggggcat agtcttgtat atgatcgaca
    15481 atttccaata aacctttgat tgagcgcatc ccataagcaa atcctccgag tccacacgtt
    15541 tcttgtccta ctaatccatg tttaagtgga atcttttcgt ccttttctcg catctccaat
    15601 cctccaacac gaatttgtga gaaaacaaaa tcgcatcctg taaaagcaag ctttggatca
    15661 tccgttgcac gaatgcgaat atttgaaaaa ccttttcttt tcagcataaa tttaacaatc
    15721 aagtacatat ccatatttct ttcttcatca atatcatata aacgtatttc agataatggc
    15781 aaccgttttt cattgttcaa aatggcttga acgattcctg gtgtatacgt actcccgcct
    15841 ccagctatag tgataatctg ttttttcatc atcatctttt cctttctatt cttctaataa
    15901 tttattgaat tctgccataa cataagtcac ttctaagccg atgataattt gataattttt
    15961 ttcagttggt ttaatgatcc cgcttatccc taattgcttg attcgctgtt cctcgaccat
    16021 ggtgggatcc actacctcta cccgtaggcg tgtattacaa ctatagacat ccaggatatt
    16081 ggcttttcct ccaaacgctt gtagcatttt tgttgccata tattcataat ttttacttgc
    16141 taaccctaac tctgtttctt ctaaggttac ttcattgcca aactctgcct tagcttcacg
    16201 tcctaatgtc tgaatgtttc tcttattgat caaataataa aaagtaacgt aatacaaagc
    16261 aaaaaagaaa attccgattg gaagaatcaa aatagcattg gtagcgattc gaaaattgat
    16321 gagataatca acaatacatg ctccgaatgt aaaaccaatt cgtatattga ataagtaaca
    16381 gacaatccct gctaaaccgg caaaaagtgc atggatcacg tacaacatag gagaaagaaa
    16441 catgaaacta aattcaacag gctcagtgat atttgcaata aatgaagttc ctgcaccgct
    16501 tcccatgatt cctttgacca tctctttatt ttctttataa gctgctttat agatagctag
    16561 acatatagct ggtataccaa acatcattac tacaaaaaaa actgataaaa acagtccagc
    16621 ctgaggatct ccgttgataa agcgtgtcat ctctcctctg aaaacttcct tgctaggaga
    16681 tgtatagctt cctaaatcgt aataaatata cgtattcaac acatggtgca gtccaaaggg
    16741 gatcagcaaa cgattcaaaa acataaatat ccccacacct aatgctccca tatcaacgag
    16801 cagttttgca aaattatcaa tcccaatttg gatgagcggc cagataaagc ccaaaaaaac
    16861 agctgcgatt gtttgtagaa tcatcaccat agtcaatggg aatttttcgc ccgcaaaata
    16921 agaaaaaact actggtaatt tttgttcttt aaagcgatta tacgtccatg ccgctactaa
    16981 accggaaata attccaccaa aaatccccat attcacttct gggtccataa tttctaagcc
    17041 ttttttcaag gtagcaatcg ctaaaaaacc agtaagtgca ggtattcctt tgtccttatt
    17101 tttgacaaaa ccgattgcaa ctcctatagc aaataagata tccaagtttc caaaaacggc
    17161 atttccagct gcaccaatta ctgggatgtt cagcatatcg tcagctgata aacgcatgat
    17221 caatcccgct aatggcatcg ctgcaactgg aagtagcatc gctcttccaa gcttctgcac
    17281 atttgattta acattcattt ttattcctcc tctattaaat atcctcatat gttactaact
    17341 caatcaaagg atcatttttc actttttgag caaatgctga atgaattaaa aattcgactt
    17401 ggtgggtacg aggatacaca aaacttgaac catttaacaa ttcctgatcc aaatacgctg
    17461 cgtgacacat gacttcgatc gttttatctt ctctcaatat catgagtaaa cttgccaaat
    17521 attcttccac actcgtattg atttgtcgtt ttttttcatc agtttctcct acgacatcga
    17581 aacaaggctc aaaataatcg acatgacgaa cttcatcttt tcgttcaaag ttgctccgaa
    17641 ccggcaaatc atattttttt gctaatgtaa caactacctc ctgattttca tccaaagtat
    17701 gagtatgatg atgactgtct aaatgagttg gtatgatccc cgcatgataa attttttgaa
    17761 tctgagcatt ccattcctga tacagttgat ctttgtcaat gttaaatgga tgctgataat
    17821 aagataagga tctgaactct ccgctttcga taagagtatc gacagttttg aggagtggtt
    17881 tgccacacgt caatgttaaa tggactccta cacctagcct aggcatttcc tttcttagtt
    17941 tcacagcatg ctcgaaaccc ggcatatttg ccatcaatgt agttgatgtc aaaattcctc
    18001 gctgataagc atccataatc ccataattca caccatggct atagccaaaa tcatccgaat
    18061 taaaaatcac ttttcccatt tcattctcct tcttttttct actaaaatag gcgcaaccaa
    18121 ataatcatag tccatttact atgtgtcatt tggttgcgcc tatagatagt tacgccctta
    18181 ttttaataga ttcttgctag atgaattgcc aaatagatga tttcattttc ttgaatggca
    18241 agttgaaatt gctgttcgat gatatcttta atctttagtg ctgtacaata cgctttgcta
    18301 tgtttaaatg tttcagtaaa aaaaccaata ttttctactg gcgtttcttc ctgataaatc
    18361 aagcgtttaa ccaggaattt gatatgaacc attaagcgat gataagtcag tgattcttta
    18421 tcataaacgt ttgaatagga tttttctaga tgggacaaaa tcgtggtcgt catttctact
    18481 atttttaagc tctttaaact attaggctct cctagctcag cattaatgat atgcatagtg
    18541 atgaatccta cttcatttga ccctaactcg gtttgatatc gatgattgat tcgctcgacc
    18601 acttctactg ctatatcata ttcatttgga taaaggaatc tcatttctgg caacataatt
    18661 gctgtgacat ctctatcttc tctttttcgt tgaatagcaa aataaatatg atctgtcaat
    18721 gtaatataga tatttgaatc taatggagag gagatcctag ctgttatcag ttcaatcact
    18781 tcttccgcaa aatccataaa ttcgattgga atctgcgaga ctatctcact gaatcgtttg
    18841 atcttttctt tagaatctaa tacaaataat ttgtcagcat cctcaacatc aaatggctta
    18901 ctcactttag cagaaaagcc aatccctttc cccatcgcaa ttttttctat tccatcgtca
    18961 tcgatcaata cagcattatg attcagcttt ttcatcacat acaccgttaa ttcacctcct
    19021 ctatatgata aaacaaaaca acttgcagac tccttcatac atatttttgt ctccaaacaa
    19081 tttttaaaga caaaaaacga cctaagaaag aaccctttct taggtcgtgc ctaattgaat
    19141 agtagcaccc tacataattt acaaaaatag tttaacacat aataaaagcg ttatcaatat
    19201 cttttttact cgttttatga taatacttgt atcgaattga tttggaggta attacataaa
    19261 aacaaaaaaa atatagcaac tctctataag aaagttgcta tattgataat tataccggcg
    19321 gccggggtcg aaccggcacg tcctcaacgg acactggatt ttgagtccag cgcgtctgcc
    19381 aattccgcca cgccggcaaa tttaaaaata ataactgggg tagctggatt cgaaccaacg
    19441 catgagggag tcaaagtccc ttgccttacc gcttggctat accccaagaa taaaaggcga
    19501 atgatgggaa tcgaacccac gaatgccgga gccacaatcc ggtgcgttaa ccacttcgcc
    19561 acattcgcca tcataaaaga tgttatttaa tttctcaata aaaaactaag atgaagacat
    19621 cttagtcaat accggcggcc ggggtcgaac cggcacgccc tcaacgggca ctggattttg
    19681 agtccagcgc gtctgccaat tccgccacgc cggcaagttg atttattagt actaaggcgg
    19741 taaccggatt tgaaccggtg atgaaggttt tgcagacctc tgccttacca cttggctata
    19801 ccgccattat actattatca atctataaaa taaagaataa attatagaaa ctggggtagc
    19861 tggattcgaa ccaacgcatg agggagtcaa agtcccttgc cttaccgctt ggctataccc
    19921 caagaataaa aagggcgaat gatgggaatc gaacccacga atgccggagc cacaatccgg
    19981 tgcgttaacc acttcgccac attcgccatg gcaggggcag caggaattga acccacacta
    20041 acggttttgg agaccgctgt tctaccttta aactatgccc ctataaaatg gaggagagtg
    20101 gattcgaacc actgaaccct aaggaacgga tttacagtcc gtcgcgttta gccacttcgc
    20161 tactcctcca tggtggcgcg ggacagaatc gaactgccga cacacggagc ttcaatccgt
    20221 tgctctacca actgagctac cgcgccatat tttaaaatta ttaattgaat aacaagaacg
    20281 acggttccga cgggaatcga acccgcgatc tcctgcgtga caggcaggca tgttaacccc
    20341 tacaccacgg aaccagttca ttatggaggt taacgggatc gaaccgctga ccctctgctt
    20401 gtaaggcaga tgctctccca gctgagctaa acctccaaca ttcaattaaa atgacccgta
    20461 cgggattcga acccgtgtta ccgccgtgaa agggcggtgt cttaaccgct tgaccaacgg
    20521 gccaggtaaa tttgctacgg agagtaaggg attcgaaccc ttgagacagt ttggcaccat
    20581 ctacatgatt tccaatcatg ctccttcggc ctctcggaca actctccaga gtgaaagaag
    20641 ctcaatactc tttctcaaaa tgag
//
LOCUS       DADLIO010000049        20360 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.049, whole genome shotgun sequence.
ACCESSION   DADLIO010000049 DADLIO010000000
VERSION     DADLIO010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20360
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.049"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            291..1430
                     /locus_tag="JOX41_001934"
     CDS             291..1430
                     /locus_tag="JOX41_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HAY6449662.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLARHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHSIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(1497..2072)
                     /locus_tag="JOX41_001935"
     CDS             complement(1497..2072)
                     /locus_tag="JOX41_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAY6449663.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQVGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(2077..3051)
                     /locus_tag="JOX41_001936"
     CDS             complement(2077..3051)
                     /locus_tag="JOX41_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HAY6449664.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPVDIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGLDGLGDTNFPMVLAKQAESL
                     HAVDFLTDYFKEKTDTSVIALGPLTNIASALKNSPSVGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFEKLKQPIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIDESICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(3075..3119)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            3334..4302
                     /locus_tag="JOX41_001937"
     CDS             3334..4302
                     /locus_tag="JOX41_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAY6449665.1"
                     /translation="MVIFYFILILIFIGISYHFLSYFYAKKLVRAGVQRGYDWYEETG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGIPKTIKSYDGLKLAGQMFLQPTQQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLIPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPDASIILHGSSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMIMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            4415..4693
                     /locus_tag="JOX41_001938"
     CDS             4415..4693
                     /locus_tag="JOX41_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAY6449666.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARREGKKIIPSCPYAKKEFEKKPEYHDVLRQS"
     gene            4811..5047
                     /gene="secG"
                     /locus_tag="JOX41_001939"
     CDS             4811..5047
                     /gene="secG"
                     /locus_tag="JOX41_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HAY6449667.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAVWMILLFVLAFLSSK"
     gene            5159..5905
                     /locus_tag="JOX41_001940"
     CDS             5159..5905
                     /locus_tag="JOX41_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAY6449668.1"
                     /translation="MKQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKADYTV
                     YAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFAVRA
                     LEEESVIGGGFFCSPLSPVETNVPENFEKYVRQVLKIAGKSEKEINEKAVSYRSLAEH
                     QLMDIQDQAAIAESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQWYPE
                     SGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            5908..8265
                     /gene="rnr"
                     /locus_tag="JOX41_001941"
     CDS             5908..8265
                     /gene="rnr"
                     /locus_tag="JOX41_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HAY6449669.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILVEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSDEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDIVGRRDLRDQLIVTIDGEDA
                     KDLDDAVTVKKLENGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHEIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILEMMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKSGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            8287..8751
                     /gene="smpB"
                     /locus_tag="JOX41_001942"
     CDS             8287..8751
                     /gene="smpB"
                     /locus_tag="JOX41_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HAY6449670.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            9053..9772
                     /gene="atpB"
                     /locus_tag="JOX41_001943"
     CDS             9053..9772
                     /gene="atpB"
                     /locus_tag="JOX41_001943"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HAY6449671.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            9825..10040
                     /gene="atpE"
                     /locus_tag="JOX41_001944"
     CDS             9825..10040
                     /gene="atpE"
                     /locus_tag="JOX41_001944"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HAY6449672.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            10131..10655
                     /gene="atpF"
                     /locus_tag="JOX41_001945"
     CDS             10131..10655
                     /gene="atpF"
                     /locus_tag="JOX41_001945"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HAY6449673.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            10642..11184
                     /locus_tag="JOX41_001946"
     CDS             10642..11184
                     /locus_tag="JOX41_001946"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HAY6449674.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            11207..12763
                     /locus_tag="JOX41_001947"
     CDS             11207..12763
                     /locus_tag="JOX41_001947"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HAY6449675.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEETLNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            12777..13679
                     /locus_tag="JOX41_001948"
     CDS             12777..13679
                     /locus_tag="JOX41_001948"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HAY6449676.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            13702..15108
                     /gene="atpD"
                     /locus_tag="JOX41_001949"
     CDS             13702..15108
                     /gene="atpD"
                     /locus_tag="JOX41_001949"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HAY6449677.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            15122..15544
                     /locus_tag="JOX41_001950"
     CDS             15122..15544
                     /locus_tag="JOX41_001950"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HAY6449678.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            16013..16243
                     /locus_tag="JOX41_001951"
     CDS             16013..16243
                     /locus_tag="JOX41_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HAY6449679.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            16340..17641
                     /gene="murA"
                     /locus_tag="JOX41_001952"
     CDS             16340..17641
                     /gene="murA"
                     /locus_tag="JOX41_001952"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HAY6449680.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNCPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            17654..17830
                     /locus_tag="JOX41_001953"
     CDS             17654..17830
                     /locus_tag="JOX41_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HAY6449681.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            17965..18261
                     /gene="yidD"
                     /locus_tag="JOX41_001954"
     CDS             17965..18261
                     /gene="yidD"
                     /locus_tag="JOX41_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HAY6449682.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            18325..18708
                     /locus_tag="JOX41_001955"
     CDS             18325..18708
                     /locus_tag="JOX41_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAY6449683.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASNQTRIIIRTGTTS
                     SAALHLYQKMGYVEIGRVKDYFIHH"
     gene            18877..19761
                     /locus_tag="JOX41_001956"
     CDS             18877..19761
                     /locus_tag="JOX41_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAY6449684.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKTQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLD
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            19878..20111
                     /locus_tag="JOX41_001957"
     CDS             19878..20111
                     /locus_tag="JOX41_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HAY6449685.1"
                     /translation="MSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYGP
                     KEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            20199..20279
                     /locus_tag="JOX41_001958"
     tRNA            20199..20279
                     /locus_tag="JOX41_001958"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20233..20235,aa:Tyr,seq:gta)
     gene            20286..20357
                     /locus_tag="JOX41_001959"
     tRNA            20286..20357
                     /locus_tag="JOX41_001959"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20318..20320,aa:Gln,seq:ttg)
BASE COUNT         6759 a         3566 c         4425 g         5610 t
ORIGIN      
        1 ttttttgcaa ctagcttctg tatatgatgt ttacaaagaa tggtacaaga aaagatcatc
       61 cttgaaaaag gaaagctaac aataactagc atcatataag agcttttaag gatagaacag
      121 tagaatagga atctatgggc aagtcctctc gtataaataa aataggaggg aagtagcagc
      181 atatttttca taaagtggct ctctttcttc atttttactt tggttgctcc tatttgaaaa
      241 ttcgagcaca ctcaaataca ataaaaagaa atggcaaggg agaggattag atgaaaaaag
      301 aagaaaaaat cgcgatttta caagagatta tccgaattaa atcagtgaat ggaaacgaag
      361 gtgaagtagc agcctatttg aataagcttt tggcaaggca tgacataaca ggagagattg
      421 tttcttacag agatggtaga gataatttga ttgctcgtta ccaaaagggc caatcaggaa
      481 aagtgttagg cctatctgga catatggatg tcgtggcggc tggtgatgaa tcgtcttgga
      541 cctatgcacc ctttgcagca gaaatccatg ggaaccgttt gtacggacgt ggtgctacag
      601 atatgaagag tggcttggca gcaatggtga ttgccatgat cgaactgaaa gagtcaggaa
      661 aaccatttaa cggaacagtc aaattattag ccactgtcgg agaagaagtg ggtgaactag
      721 gtggggaaca gctcacgaaa gcaggctatg tagatgactt agatgccttg atcatcggag
      781 agccaaccaa ttacagtttg atgtatacgc acatgggatc aatcaactat acagtcacct
      841 cgcacggaaa agaagcgcat agctctatgc cagaccaagg ttataatgca atcaatcacc
      901 taaatgaatt cattacgaaa gcaaatgctg aaatgaatca cctcgctgaa acaatcgaga
      961 atcctgtcct aggaaaaaca atccataatg ttacattgat cagtggcggg aatcaagtca
     1021 acagcatccc aagccatgcg cagctccaag ggaacattcg atcgattcca gaatacccaa
     1081 atgataaaat cattgcattg ctgcaatcaa tcgtcaatga attgaatcaa gagacagact
     1141 atcatttgga attgatgatc gattacaaca aaatacctgt caaagctgat ccagattctc
     1201 ctttgattca ttccattcag caacaattca gccagccatt acctttagtt ggagcggcag
     1261 caacaacgga tgcagccgaa tttacgaaag ctaaccattc cttcgacttt gtcgtctttg
     1321 ggcctggtgt cgttactttg cctcatcaag tagatgagta tgttgaaatc gataattatt
     1381 tggatatgat cgaaaaatat caaggaatta ttttatccta cttagcgtaa gattttttta
     1441 ataaatgaaa aaacagagcc agattagcat tattttgcta atccagctct gtttattcag
     1501 cctatttttc tttttgaata tatcaagcgt tggggcaaca tagtgatgac taatgaaaca
     1561 acgacgatag acaacaagcg atcaaggtag tctgtaccca cctgtaccaa gatcacactt
     1621 gttgtctgac ttaaacctaa cccatgtaat agctgaacga tcatactgga tcctgaggag
     1681 gtgatcccgc caaataactg aacggtaatg atcgaagaaa cgatcgttcc aggtaccgac
     1741 aaaatcaaag cgagtaataa cagtttcaag ctgtttttat ctttgccgag atatcttggc
     1801 aaaatcaatc cagcaagcaa gcctgtgaga atttggattg gcgaataata cagagaaaaa
     1861 atatctgtag tcactccact taaaataccg ctggacaatc ctgtcagcat tccaggtaca
     1921 ggcccaagca atgcaccagc aaaaatcgtt ccgatagaat cgagatagat tggcaaacga
     1981 agccataaag caatcgttcc tccaatataa ttgatcccaa tacacaaagc catcactgta
     2041 agtacgcgag ttgccatttt gtttttattc attttgttag cccatcttta acctttccaa
     2101 atctttcata atcgtttctt cttgtgcatt taaaagaacg gttaaaaact ttcggaaaaa
     2161 aagacgagta tctacttttg tcataatttt actgttagca ggtttctgcc aaaattcata
     2221 acgatcaacc aatgtttgtc cgcgacttat tccttgagtt tctacagcag tgaagctttt
     2281 aaagccttca cagatggact catcgataaa ataagcaaca gctaatggat cattgatgac
     2341 acatcctaag attctttctt gtttccagtg aaagtcaaaa taaaaacgag tgatcgcttt
     2401 tagatactct ccctcttcag gattcatttg gcagcaatat tcaaggatag tcggtgtcaa
     2461 gacgatttct cttgtcacat ctaacccaac catttctatc ggttgtttga gcttttcgaa
     2521 tacataagaa gctgcttcag gatcacacca gtaattgtat tcagcaactg gtgaacagtt
     2581 accatggctt ttgtaagttc cgcccattga gacaaaacga tccatatgtt tcccaacaga
     2641 tgggctgttt ttcaaagcag aagcgatatt ggtcaaaggc cccaaagcaa tgactgatgt
     2701 atctgttttt tctttgaaat aatcagtcag aaaatcaact gcatggagcg attctgcctg
     2761 tttggctaag accatcggga aatttgtgtc ccctaatcca tccaacccat gagtgtcttg
     2821 cgcactaatg aaaggttgct tcaaaggttt ttccattcct tgataaacag ggatatctaa
     2881 acgatcacag cgctccaaac atttcagcac attctgcgta ccgatatcta cagggacatt
     2941 cccgcaaacg acggtaatag caactacttc gatatcaggg gatttgacag ctagtgataa
     3001 agctaaagtg tcgtcgatcc ctggatcgca atcaataatt actttacgca ttatttccaa
     3061 tctcctttct ttagagatac ttagtttttt attctgggaa gtttccgaac cagtccaaga
     3121 cgagtgtctt gtttataatg cacgaaatta gtatactggc ttttattgtg aatgtaaatg
     3181 ctctcttaca agtaaatcta ttgagaagaa ctttaagtaa atgatacaat gaaaaagaaa
     3241 tggaatttac gtgtgccgaa gaaaaagaat cctattgatc ggtatattgt ataataaata
     3301 gattatagtt tggcagaaag cggcgggtgt acgatggtta ttttttattt cattcttatt
     3361 ctgatattta taggaatcag ttaccatttt ctttcttatt tttatgcaaa gaaattagta
     3421 agagcggggg tacagagagg ctatgactgg tatgaagaaa ctgggcaccg cttgatggat
     3481 cctgctgcag tcacgtcagt agaaaaaaag cgacaaaaat tagaagaaga gtgtgaaagc
     3541 ttctgggaac aaggaatacc gaaaacgatc aaaagttatg acgggttgaa actagctgga
     3601 cagatgttcc tccaaccaac tcagcagaat aaatgggtca tttgtgtaca tgattatcga
     3661 agtacaggga aaagagatat gtctcatata ggtaaaagat atgcagagaa aggattcaac
     3721 gttcttatac ccgatttacg tgcgcatgga gaaagtgaag gagaaatcat cggaatggga
     3781 tggctagacc ggctagattt aattgcatgg atccaactca tcttagatga acaaccagat
     3841 gcatccatta ttttgcacgg cagttcgatg ggcgcttcta ctattatgat ggcaagtggt
     3901 gaaaagcttc catctgcagt caaaggattt atcttagaca gcggatatgt ttctgtttat
     3961 gcggaatttc ggtatatgtt aagtaaaatc acggtctttc ctaaaaaaat gatcatgaga
     4021 tatgcgaatc actatgctca gaaatacgca ggttattctt taaagcaagc atcagctaca
     4081 agacagcttg gtagtaacca tttgcctttg ttagtcatcc atggtgaaag agatcatttt
     4141 gttcctacag aagcagcata cacgattcaa aacgctacgg caggggataa agcattactg
     4201 cttgttccag aagcagaaca tttggaagca tcgatgaaag atccgaaaac ctattggaca
     4261 gtgatttttt catttattga acaaagaata acgatggatt gattttctct tcctttttgt
     4321 aagcaacacg aggataaata attgtttata gaccatgaga ctgttaaaat aaggtaggaa
     4381 taaaaaaata tcagttattt gaggagtgcg gcatatggaa atcaaagagg aaaaaaatcg
     4441 tcttgcttta ttcaatgatg agcaacaaga aatcggagaa atgacatggt cggatgcggg
     4501 gccagacatc atgatcattg accatacatt tgtcgatcca gcatatcgtg gtcaaaaatt
     4561 agctgaaaag ctagtgtata ctggagtaga actagcaaga cgagagggga aaaagattat
     4621 cccttcatgc ccttacgcaa aaaaagagtt tgagaagaaa ccagagtatc atgacgtctt
     4681 acgccaatca taataataac agctgaaaga tttgcacttt cagctgtttt tccatttata
     4741 tagagttgtc acggagtttt atctatgata aagttaaaga gacgatatct tttgggaagg
     4801 aggctgctat atgtataatt taattttggg aatcgtgatc gttttatcga ttgttatggt
     4861 cattgcgatt atgatgcagc caagcaagca aaatagtgca gcgagtgcat ttaccggcgg
     4921 tgcggatcaa ctattcggca aacaaaaagc tcgcggcttt gaagctgtca tgcagcgatc
     4981 aactgcagtc atgggagctg tctggatgat cttattattt gtcctagcat ttttatcttc
     5041 gaagtagtcg aataagcctc tcgcacaacg gcgggcggct ttttttattg caaagagaac
     5101 gcttaagaag aagttatgaa agaaactatg gtaaaatgag gcgaaagagg tgaaacgagt
     5161 gaaacaatta ccaaaacccc tttatgcaaa acatggaaaa cgagcagttt tgctgcttca
     5221 tgcgtactca ggaagtccaa atgatgtccg gatgctcgca cggtttttag aaaaagcaga
     5281 ttatacagtc tatgcgccgc tatttaaagg acatggaacg atggagccat atgatatctt
     5341 gcaagaaaaa gcagaaagct ggtgggcaga tactaaaaaa gctatccatt ttttacagtc
     5401 tgaacagttt tctgatattg ccgtattggg attatcgatg ggtggcatct ttgctgtacg
     5461 ggcactagaa gaagaatcag taattggcgg cggttttttc tgttcgcccc tgtctcctgt
     5521 agaaacaaac gtgcctgaaa attttgaaaa atatgtacgt caagtgctga agatagcagg
     5581 caaatcagaa aaagaaatca atgaaaaagc tgtgtcttac cgctcgttag ctgaacatca
     5641 attaatggat atacaagacc aagcagcaat cgcagaaagt agactatcag atatccaaca
     5701 gccaatattt ttagctcaag ctgggaaaga tgaaatgatc gacccaaatg gtgtatttga
     5761 aacggcacgc aaattgagcc gccaacgagt gacacttcaa tggtatcctg aaagcggtca
     5821 tgtgattaca gttggcacag caagacgcga attagaaaaa gacgtgttgg aatttttaga
     5881 aaaattacct tggaatgagg aataaatatg acaaaagaaa caataaaaga gaaaattctc
     5941 tttttcatgg aaagcagtcg caaacgtagt ttttctatgg aagaaatcgc tgaaggtcta
     6001 ggctttcaaa aaagcgatga ttttaaatta ctagtacaaa cgattgctca aatggaaaga
     6061 gaacagagta tcgttttcaa taaaaaagga aaagtcaaac ttcctttaaa accgatcttg
     6121 gtcgaaggga catttcgggc aaatgaacga ggatttggat ttgtaacgat tgatcccgaa
     6181 gaagatgata tctatatccc gaaagaagcg actggctttg caatggatgg ggataccgta
     6241 gcaattgata tcatgaagcg agcaaataca gatatggatc gcggagcaga gggaaaagta
     6301 gtggagattc gagaccgagc gactactcag ttagccggag aatttgttgc ttattcagac
     6361 gaagagatac aggaaacgga tctttatggt gtggtcatcc cgaaagatag aaagcttaac
     6421 caattcaaag tgtatgcagc ggcagaggga gttcgtccag ttgacggaag tattgtattg
     6481 atcgaactga cccattaccc tgaaaaaggg tatgcaacta gtttagaagg gataatcaag
     6541 caagtgattg gtcataagaa tgaccctggc atggatatcc tctcgattgt cgtggctaac
     6601 ggtattccta caaaatttcc tgatgatgtg ttatctgagg cagatgaagt tccagaccag
     6661 atcagcgaaa aggatattgt tggacgcaga gatttaagag atcagctcat cgttacgatt
     6721 gatggagaag atgcaaaaga tctagatgat gcagtgacgg tcaaaaaatt agaaaatggt
     6781 aattattttc ttggagtaca cattgcagat gtatcttact atgtgacgca aggcagtcaa
     6841 ctggacagag aagcatacga aagaggaaca agtgtctatt tgaccgatcg agtgattccg
     6901 atgatcccac aacgtttatc caatggtatc tgttcattga atccccatgt tccacgactc
     6961 accatgagtt gtgaaatgga gatcgatcca aatggacaag ttgtctctca tgagattttt
     7021 ccaagtgtga tccaaacaac agaacggatg acctacacag ctgtcaatca aatcttagaa
     7081 gatcaagatg aagaaacgat gcaacgttat gctcagctcg tgcctatgtt ccaagaaatg
     7141 ggtgaattgc atcgaatcct tgaaatgatg cgaatcaaac gtggagcgat ttcttttgag
     7201 gatcgtgaag cgaagatcct tgttgatgct gaaggacacc caaatgatat ccagctaaga
     7261 agcagaggga taggtgaacg cttgatcgaa tcctttatgc ttgctgccaa cgaaacggta
     7321 gctgaacatt ataataaatt aaatcttccg tttatttatc gaatccatga acagccaaaa
     7381 gaagaaaaaa tgcagcgctt ctttgatttt gcttcagctt tgggcattct ggtccgagga
     7441 acgaaaggaa cgatcacacc aaaagattta cagcatgtga tcgaaggagt agaagacaaa
     7501 ccagaagctg cagttatcaa tactatgttg ctaagaagca tgcaacaagc acgctattca
     7561 gaagacaatt ttgggcatta tggcttagcg gcagattact acacacactt tacatctcct
     7621 attcgacgct atcccgatct aatcgtccat cgtctgatcc gttcttacag tgaagataaa
     7681 agtgaaagca atcaaagttc gtgggctgcg gaacttcctg aaattgcaga tcatagttct
     7741 aagatggaac gtcgtgcagt agaaacagaa cgtgaagtag attccatgaa gaaagcagaa
     7801 ttcatgatgg acaaagtggg agaagaattc gatgggatca tcagctctgt tgtgaaattc
     7861 ggcctgttta tcgaactgcc gaatacagta gaaggattga tccatatcaa tgaattgaaa
     7921 caggactact tccattttgt tgaaaatcat ttagctcttg taggtgaaag aactggtctg
     7981 acttttaaaa tcggacaaaa agtgcgcgta aaagtagtca aagctgatcc agatgaacga
     8041 gcagtggatt ttgaactcgt ttccgcagaa gaggtcactg cgttggaacg tccaaaagca
     8101 cgcaatggaa aatctggaaa acgagaagga aaacaagcag gcaaacgctc agaaaaaaat
     8161 ggcaagaaga acaaacgata tagtgatagt aagcaaacgt tcggtaagaa aaaagggaaa
     8221 aagccatttt acaaaggtgt caaaaagaag aaaaagaaaa aataaaatga gttggaggaa
     8281 acagctatgc caaaaggcga gggaaaacta attgcacaaa acaagaaagc tcgccatgat
     8341 tattcgatca tcgacacgat ggaagcaggg atggtcttgc aaggaacgga gatcaagtcg
     8401 atacgaaaca gccggatcaa tctgaaagat ggatttattc gcgtccgcaa cggggaagct
     8461 ttcttgcata atgttcatat cagtccttat gaacaaggaa atatttttaa tcatgatccg
     8521 ttgcgcacga gaaagttatt attacacaag aaacaaatcg ttcgtcttga aaacgaattg
     8581 aaaaacactg gaatcactgt tgttccttta aaagtctata ttcgtaacgg ctatgccaag
     8641 gtattgattg gtctggcaaa agggaaaaaa tcgtatgata aacgggaaga tttgaaacga
     8701 aaagatatcg atcgacaaat tgatcgaaca ttaaaaaatt tctctagata atttcattat
     8761 cctttttcgc atattcggtg cttttgcttt tacttaatga taaaatttgt tagcatttaa
     8821 tctgataaaa catgattatc acaggttttt tcttagatca ggagcaccgt gcatggggaa
     8881 aaattcgctt cgtttttgac tgaaataaaa aagtgtctaa ttttcatgaa aatgttttga
     8941 attttctgtt tcatggtggt atgataccgt gtggttagaa accgattgga aaaaaccaga
     9001 tacgcacatg aattgatttt atgtgaattt cggggaaaag aggtgaaatg gattggatga
     9061 acgctcgcta acgtttcaca ttggaccaat ttggtttgat ggtacagttt gtataatggt
     9121 gttactgacc tgtttgattg ttttcttctt agcttacttt tttacaagaa atcttaagtt
     9181 gaaaccaaca ggcaaacaaa atgcgataga atgggtcatt gattttagtc gaggaatcgt
     9241 aacagataat ctgcctagaa aagaattgag caatttccat ttgttggcat ttacattgtt
     9301 tttatttgtt tttgttgcaa acaacatagg tttagtaaca aaaatcgtct tacctaacga
     9361 aacaacactt tggaaaagcc cgacagcaga cccgtttgtt actttaactt tggcatttat
     9421 aatgatctta cttactcact tattcggggt gaaaaagtta ggcttcaaag gatatttcgt
     9481 aaattcgttc ttgaaaccct atagttttat gtttccgatg aaactgattg aagaatttac
     9541 aaacttatta acacttgctt tacgtcttta tgggaatatt tatgcggggg aagttttgct
     9601 aaccttgatt gcaaaaatga tgacaagctt aggctggttc tcattaccat tagcaattcc
     9661 attagagatg gtctggatcg cgttctcctt gtttattggg agcatccaag catttgtctt
     9721 tgtcactttg tcaatggttt atatgagcca taagattgaa gtagaagaat aatactcggt
     9781 taaaaaacaa actactattt atctatttta ggaggaaaac aattatgaat tatatcgcag
     9841 cagcaatcgc aatcatggga gcagcaatcg gagccggtta tggtaacggt caagttatct
     9901 ctaaaacaat cgaatcaatg gctcgccaac ctgaaatgtc tggtcaattc cgtacaacaa
     9961 tgtttatcgg ggtagctcta gttgaagctg ttcctatctt aggggtagtt atcgccttga
    10021 ttctagtttt tgccgtttaa ttgaatcagt attaaggcag aaacaacatc gtttgttact
    10081 gcttttttac atggaaacta gaaatactcc aaagaaagga aggctcgcct atgctgaatc
    10141 aattggcaat tgcagaagtt ggcaatgcga tgttaggtaa tatcatcgtt gtcagcggct
    10201 catttttgat actactggct ctcttgaagc actttgcttg gggaccaatc agcgatattt
    10261 tgaaaaaacg tgaagacaag atcgccaatg atttagattc tgcagaacaa tctcgcatca
    10321 actcagcgaa aatggaacaa gaacgcgaac aacaattgtt agcctctcgt tctgatgcag
    10381 ctgatatcat caaaaatgcg aaagaaagtg gagaattaag ccgccaaaat attttgaagg
    10441 atgctcaaga agaagcagct cgtctaaaaa gcaaagccca agctgatatc actgtagaac
    10501 gtgattcagc gctgaactct gtaaaagacg acgttgcaga actctctctt caaatcgcgg
    10561 aaaaaatctt gaacaaagaa ttatctccag aaatgcatga atcattaatc aatcaataca
    10621 ttgaaggtct aggttcttca aatgaaacta gataaatata cagtaggaag acgttacggg
    10681 aaagctttat ttgaactggc gatcgattca aatcaagcag aagaaatcta tcaagatctc
    10741 gtaagtttac gtcaaatcta tgaacaagta cctggattag ggaatatgtt aagtgatgtt
    10801 cgtctagaac ctcatgaaaa acgagaaatc atggacaagc ttgtcagcgg ttatgatgga
    10861 atcgttaaaa actttttaga agttgtttat gagtataacc gaatggatga ccttttgttc
    10921 atgattgaag aatatgaacg tcgatatgat gaacatcaag ggttactatt gggaagtgtc
    10981 acaacagcag tcccactttc agacgaacaa cgaatacaat tagaaaagaa tgttgcaaaa
    11041 acaatggact atcaatcagt tgaattaaaa caaatcgttg attcttctat tattggtggc
    11101 gcgattgttg aagccaacca tcgagtaatc gacggaagca ttcgcacgca attagaaaaa
    11161 atgcgtaatc aattaaacag atagtacaaa gaggtaggtg aatcgaatgg ccatcaaagc
    11221 agaagaaatt agtgccttga ttaaagaaca aattgaaaat tatcaaaacg tgctttcagt
    11281 cgaagaaatc ggtaccgtaa cttatgtagg tgacgggatc gctcgtgcac atggtttaga
    11341 aaacgcgatg agtggtgagt tgcttgaatt ttcaaacggc tcatacggaa tggcgcaaaa
    11401 cttagagtca aatgatgtag gtatcattat ccttggcgat ttcgagtcca ttcgtgaagg
    11461 agataaagta aaacgaacag gtaagatcat ggaagttcca gttggagagg ccttgatcgg
    11521 tcgggtagtc aatccgctag gtcaaccaat cgacggacta ggtgaaatcg ttactgacaa
    11581 agctcgtcca gtagaagcga tggcaccagg tgttatgcaa cgtaaatctg ttaacgaacc
    11641 aatgcaaaca gggctaaaag cgatcgacgc ccttgtgcca atcggacgcg gacaacgtga
    11701 attagtcatc ggtgaccgta aaacagggaa aacttctatt gcgattgata cgatcatcaa
    11761 ccaaaaaggt caagatatga tctgtatcta tgtagcaatc ggacaaaaag attctacagt
    11821 tcgtacacaa gttgaaacat tgaaaaaata tggcgcaatg gattacacaa tcgttgtgaa
    11881 tgccggtgcg tctcaaccag caccattact ttatatcgca ccatatgctg gtactgcaat
    11941 gggtgaagaa ttcatgtaca acggtaaaca tgtattgatc atttttgatg atctttcaaa
    12001 acaagctgtt gcttatcgtg aactttcctt gctacttcgc cgtccaccag gtcgtgaagc
    12061 ttatcctggg gatgttttct acttgcactc acgtttatta gaacgtgcag caaaattaag
    12121 tgatgatcta ggcggcggtt caatgactgc tttgccattt gttgaaacac aagctggaga
    12181 tatctctgct tatatcccaa caaacgttat ctcaatcact gacggacaaa tcttcttaga
    12241 aagcgacttg ttctacgcgg gtactcgtcc agcggttgat gccggactat ctgtctctcg
    12301 tgtagggggt tctgcgcaaa tcaaagcaat gaaaaaagtt gctgggactt tacgtctaga
    12361 cttagcaagt tatcgtgaat tagaagcatt tacacaattc ggttctgatt tggatgcggc
    12421 aacacaagca aaactaaatc gtggacgccg tacagtagaa atcttgaaac aaaaactgca
    12481 tgcaccgcta gctgttgaga aacaagtagt gattttgtat gccttgacac atggattctt
    12541 ggacagtatc cctgtagaca gtattttaga cttcgaacat gaattattcg aatatctgga
    12601 taccaatcat tcagatattt ttgaaacaat ccgtacaaca aaagatcttc cagaagaaga
    12661 aacgttgaac agtgcgattc aggaatataa agacatgttc ttagctacaa aaggaaataa
    12721 ttcctctaca gaagataaat tgaaatccat tcaaaatgca tagtgaggtg agatgaatgg
    12781 gtgcttcatt aaatgaaatc aagacacgta tcgcttcaac gaaaaaaacg agccaaatca
    12841 cgcgggcaat gcagatggtg tctgcttcta agttgacaaa atctgaagct tcttcacaga
    12901 agtttcaggt ttatgcaaca aaagtaagag aaatcgttac gcatttgact gctactcagt
    12961 taaatgatat tgcctcagaa aatcctagag gggatatcaa ttacaacagc atgctgctca
    13021 gccgtcctgt gaagaaaacc ggttatatcg tcatcactgc agatggcggt ctggtcggtg
    13081 gatataacag ttcgatattg aaacaaacga tgtctatttt agaagaagac caccaatcac
    13141 ccgatgatta cgtgatgatc gcaattggcg gaactggtgc agacttcttt aaagcacgcg
    13201 gtatcaacct agcatatgag ctgcgcaatt tatctgatca gccaagcttt gatgaagtcc
    13261 gcaaaatcgt aaatatggca acaactatgt accaaaacga agtattcgat gaattatacg
    13321 tatgttataa ccatcatatc aattcgctaa ctagtcagtt tcgtgtagaa aaaatgctgc
    13381 caatctcaga cttagatcca gaagaagcaa cgactttcga acaagaatat atttttgaac
    13441 cttcaaaaga agaaatcttg tctcagttat tgcctcagta tgctgaaagt ttgatctacg
    13501 gtgcgatcgt tgacgccaaa acagcagaac atgctgctgg tatgacagca atgaaaacag
    13561 caactgataa tgctgctaat atcattgatg agctgacggt ttcttataac cgtgcaagac
    13621 aaggggctat tacccaagaa attaccgaaa ttgttgccgg agcttcggca ctagaatagt
    13681 attgagattg gaggaaaaaa gatgagttca ggcaagattg ttcaagtaat cggtcccgtt
    13741 gtcgacgtgg aattttcttt agaccaatcc ttaccagata tcaacaacgc attagttgtt
    13801 tataaaaatg acgaaaataa atcaaaagtt gttcttgaag cagcgttaga attaggggac
    13861 ggagtgatcc ggaccattgc gatggaatca acagatggtt tacaaagagg aatggaagtc
    13921 attgatacag gcaaagcaat ctctgttcct gtaggtaaag aaacattagg tcgcgtattc
    13981 aacgtactag gagatacgat cgatttagaa acacctttcc cagaagatgc ggaaagaagc
    14041 gaaattcata aaaaagcacc agcctttgac gaattaagta caagtacaga aattttggaa
    14101 acagggatca aagttatcga tttgcttgcc ccatatttaa aaggtgggaa agtcggacta
    14161 ttcggtggtg ccggtgttgg taaaaccgta ctgatccaag aactgatcca taatatcgcc
    14221 caagaacatg gtggtatttc tgtatttacc ggtgtaggtg aacgtactcg tgaaggtaat
    14281 gacttgtatt atgaaatgaa agattcagga gttatcgaaa aaacagccat ggtgttcgga
    14341 caaatgaacg aaccaccagg tgcacgtatg cgtgttgctt tgactggttt gacgattgcg
    14401 gaatatttcc gtgatgtaga aggtcaagat gtactgttgt ttatcgacaa cattttccgt
    14461 ttcactcaag ctggatctga agtatcagcc ttgttaggac ggatgccttc tgcggttggt
    14521 tatcaaccaa cattggcaac agaaatgggt caattgcaag aacgtatcac atctacgaaa
    14581 aaaggttcga tcacatcgat ccaagcaatc tatgtgccag ccgatgacta cactgacccg
    14641 gcgccggcaa cagcattcgc ccatttggat gcgacaacca acttggaacg taaattaaca
    14701 gaacaaggga tttatccagc ggtagatcca ttggcttctt cttcaagtgc tttagcacct
    14761 gaaatcgtgg gagaagaaca ttataaagta gcaacagaag tccaacacgt attgcaacga
    14821 tatcgtgaat tacaagatat cattgctatc ttaggtatgg atgaattatc cgatcaagaa
    14881 aaagtgttag tttctcgtgc ccgcagagtc caattcttct tgtcacaaaa ctttaacgtg
    14941 gctgaacaat ttactggtct tccaggttca tatgtccctg tagaagaaac agtgaaagga
    15001 ttccgcgaaa tcttggaagg caaatacgat gatcttcctg aagaagcttt ccgaagtgtt
    15061 ggccgaatcg aagacgtcgt agaaaaagcg aaaacactag gctactagaa aggggtgccc
    15121 catggatcaa tatttaacag taaatgtggt aactcctgcc ggtttggtct atgatcacca
    15181 tgcagctatc gtcgttgcac gtacgacagc tggtgagctt gggattttgc ctaaacatgc
    15241 accaatcatc gttccattga cgattgatga agttcgtgta aaacgaacag attcagatac
    15301 ccacgtcgat tggatcgctg ttaatggcgg aatcatggaa gttcgtgata atgttgtttc
    15361 aatcgttgct gatagtgcgg aacgtgaacg tgatatcgat gtatctcgtg cggaacgtgc
    15421 aaaacaacgc gcagaacgcc aaatcgaaga agcaaaagca aaacaagata cgaacgaatt
    15481 gaaacgggca actgttgcgt tgcaccgagc aatcaatcgt atcaaagtat ctaagcactc
    15541 ataaaatgag atgcggatgt ttatccgtgt ttaagaacag taaaaagagg ttatgacaga
    15601 agtggtcagc ttcaagacat aagaaggaat ttacgaaaat tgcttctcaa atttttgtga
    15661 aatctcagct tatttttcga agaagctact tctggaacac cgtatatcag aggttgtgaa
    15721 atcagcgttt tgtcctgagt attagagaaa caaatggaaa atagttcctc atattttgcc
    15781 gttttttgag ctaataccga gggtcagatg attgaacacc gtttatttgg aataagggac
    15841 tgcgacaaga cttttgtctc agtccctttt tttgcatatt tttagcattt atttcctaaa
    15901 aaatgtaagg ggattcctat atttttaagt atacttgttt ttccttttat acattttatg
    15961 gtattatcat tttattagtt attataaaac aatcgttaga aaggacgtca ttatgcaagt
    16021 atacggaatt gatgcggtgc ttcgaatcgt gagtcatttg gcgtttatct acttagcctt
    16081 ctggtcttta cgttcgttac gcattgaaac ttttttcaga ccaatgcata atacgcaaat
    16141 tagaatggca atcgtacttt tttcaatttt tttagggtac actgcaagta attttttctt
    16201 agaagttatc gctttatgcc gaaatctttt cgttagcctg taaattttaa aaaaaggtac
    16261 tattttaaaa gcaaggatgt tataatagaa aagattttga gtaagtgtat gctcattgga
    16321 attttttgga gggaacaaca tggaagagat catcgtaaga ggtggcaatc aattaaatgg
    16381 aacagtaaga attgaaggag ctaaaaatgc tgttttgcct attttagctg ctagtttgtt
    16441 agcagaagaa ggtattacga cattagacaa cgttccgatt ctttctgatg tcttcactat
    16501 gaatcaagtg attcgtcact taaacgtaga tgtagatttt gatgaacaaa agaatcaagt
    16561 aacaatcgac gcttcaagac aattagaaat cgaagcgcct tatgagtatg ttagtcaaat
    16621 gcgtgcttca atcgttgtga tgggtccgct acttgccaga aatggacatg caaaagtagc
    16681 tatgcctggt ggatgtgcga ttggtaaacg accaatcgat ttgcatttaa aaggatttca
    16741 agctttagga gcaaaaatta ttcaaaaaaa cggctatatc gaagcaattg cggatgaatt
    16801 gatcggtaac acgatttatt tagatttccc tagtgtgggt gctactcaaa atatcatgat
    16861 ggctgccgta aaagcaaaag gaacaaccat cattgaaaac gtagctcgcg aaccagaaat
    16921 cgttgattta gcaaacattt tgaataaaat gggcgctcaa gtctatggag ctggtactga
    16981 aacaatgcgt attgaaggcg tggatcattt acatgcagtc aaccactcaa tcgtacaaga
    17041 tcgtatcgaa gcaggtacct ttatggttgc tgctgcaatg acacaaggca atgtgctgat
    17101 tgcagatgct atctctgaac ataactgccc attgatttct aaattgatcg aaatgggtgc
    17161 agaaatcatt gaagaagaag gcggagtccg tgtcatcgga ccaaaacata tcttacctac
    17221 agatgtaaaa acgatgcctc atcctggttt ccctacagat atgcaagctc aaatgacagc
    17281 tatccaatta gttgcagaag gtacaagtgt ggtgactgaa acagtgtttg aaaatcgttt
    17341 ccaacattta gaagagatgc gccgtatgaa cgctcatgtc aaaatcgacg gaaatgtagc
    17401 aatcatggat ggaaaccatg aattgcaagg tgcagaagta tatgcaacag acttgcgggc
    17461 agcagcagca ttagttttag ctggcttgaa agcaaatgga atcacacgtg tgcgtaactt
    17521 gaattatcta gaccgtggat attataattt ccatatcaaa ctacagcaat taggtgcaga
    17581 cgtcgaacgt gtagacatgg atcaaacttc tgctgaaaaa acagcacaaa cgattgctta
    17641 aggaagtggc tgaatgagta accaacgata tatcttatta actttgataa agattttagt
    17701 ggtgatctta ttgcttatcc ttctttttgt ggccggaacg atgatcggat atggtgtcat
    17761 cggtggcggc aatccattta aagtattcca gccaagtttg tggattcata ttcgagactt
    17821 ttttcattga taaataagaa tcacagtggt tctagtcgat atgaagtgag ccatgaagca
    17881 gaacatgata aaagaaaaca gaagggaacg ttgacgttag tcgcgatccc tttttttagt
    17941 aaaagaaaag aaggaatcta attgatgaag aagatattga tttatttagt tagaggatat
    18001 cagcgcttta tttcgcctgc atttccacct agctgccgtt attacccaac ctgttccaat
    18061 tatatgataa aagcaattca aacccatggt gcgctaaaag ggacggtaat ggggactgca
    18121 cggatcttac gctgtcatcc ttttgtcaaa ggcggtatcg attatgtacc attgacattc
    18181 cgattaacgc gaaataagaa agataaaaaa gaaccagatt ataaaaaggt tgtgaaaaat
    18241 acgggtagca ctgagcgata aagaaaaaga ggaaatttat tgtcaaagta acaactccgc
    18301 aactacttat atgggggaca aaaaatgatc gaagaactaa acaagaaaga tttaccatgg
    18361 tccttgttat tagatgcaga tcctgataaa gaaaaagttc aagtatatgt ttccagaggg
    18421 agtggctgga tatggaaaga aaaagaaaaa acaataggtg tactgatcta tgtggcaagg
    18481 gaaaaagaat acgaaatcgt caatgtagca gtaaccccaa cgtatcaagg aaaggggatt
    18541 ggcggaaaat tacttgagac agcttttcag aagctttcac agctagcttc aaaccaaact
    18601 cggatcatta tacgtactgg cactactagt agcgctgcgt tacacctcta tcaaaaaatg
    18661 ggctatgtgg agattggtcg agtcaaagac tattttatcc atcattaatc tgagcccatt
    18721 tttgaaaatg gagatcaatt aagggatcaa gtgattttag caattcactt acctaaaaat
    18781 agctttaact aataaacttt caattcgaga aaatgctttc aaatgctaaa tagatacatt
    18841 acaatagctt tagcaaacaa aaaggagaat atttttatgg gaatattagt ttttgatttt
    18901 ggtggatcgg ctgtcaaata tggttgttgg gatggcaaag agattaaagg taagggacaa
    18961 tttgcaacgc ctgaatcttg ggaagaaatg aaaacgcaat tatttcaagt ttataaaaaa
    19021 atactcgttt cttttgaagt cgaaggaatt ggaatcagct ctcctggagt agtgaataat
    19081 gagaaacagg tgattgaggg aatcagtgcg attccttata ttcatggatt taatattttc
    19141 cgagatttgg aaactctgtt tcaactccca gtaacgattg aaaatgacgc caactgtgcc
    19201 ggaatggctg aattttatga aggtgctgcc cgtgattatc aagatgttgc ttttgttgtg
    19261 gcaggaactg ggattggcgg ggcgttgttc acgaaaggac aaataaataa aggggcacat
    19321 ctttacggtg gagaatttgg gttgatgttc ttagatggcg ataagacatt cagtaaactt
    19381 ggtacagcgg tacagatggc ttggcgttat tgtgaacgca aaggtctcga taaaaatgct
    19441 tataccggaa aagatgtctt tgaattagca gaaactggag atgcaatagc aaaagaagaa
    19501 gttgagagtt tttatacgta tcttacaaag ggattattca gtattcaatt ttcgtttgat
    19561 ccagaagtga tcgtattagg cggcggggtt tctgcaaaag aagggctcat tgatgagatc
    19621 aaaagccgaa tgaagaagct gacagaacaa ttcgatctgc atgatttcga accgcagatt
    19681 ttattatgtg agtacagaaa cgatgctaat cttgtaggtg cagcagcaaa ctatctcgct
    19741 gtacgtcaag gagagaatta agagctttag agaaggtgca gcttgcataa aagaagagaa
    19801 tgaaatgaat aggagatttt tacctaagga atgttttatt tgctgcagta tgataaaata
    19861 tctgagaggt gaaaatgatg tcaaaaaaaa ataaagatat tgaagtgcgt atagaagaag
    19921 tgaaaaaaga tatcaaaggt aagaattatg aagtcactca gttatttata gggaaaaaaa
    19981 tgattggtga gatcttagcc tatgggccaa aagaatatga aattttcttt ggtgaagaag
    20041 attttggaaa agaaaaaagt cttgaaaatg cgatagaaac agtgattcga cactggaatc
    20101 tgcacgaata aaaaaatatc aaaaaaactt tcaataaagg gttgcaaaaa tctggaaaat
    20161 taggtattat aactaagtca ggttgataca aacctttcgg aggagtagcg aagtggctaa
    20221 acgcgacgga ctgtaaatcc gttccttagg gttcagtggt tcgaatccac tctcctccat
    20281 ttcattgggg tatagccaag cggtaaggca agggactttg actccctcat gcgttggttc
    20341 gaatccagct accccagtat
//
LOCUS       DADLIO010000050        19694 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.050, whole genome shotgun sequence.
ACCESSION   DADLIO010000050 DADLIO010000000
VERSION     DADLIO010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19694
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.050"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(216..446)
                     /locus_tag="JOX41_001960"
     CDS             complement(216..446)
                     /locus_tag="JOX41_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449686.1"
                     /translation="MMEDFIRKNISDEYADFYEQSSKKDKFQMDVSILAILAFSENNQ
                     PVIAKKETVLSEGKIKTRYILEVETKFKNRSE"
     gene            1063..1725
                     /locus_tag="JOX41_001961"
     CDS             1063..1725
                     /locus_tag="JOX41_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449687.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
     gene            1804..5031
                     /gene="fss3"
                     /locus_tag="JOX41_001962"
     CDS             1804..5031
                     /gene="fss3"
                     /locus_tag="JOX41_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HAY6449688.1"
                     /translation="MKKPRFKNWRLLATLSLLCQTIGGSLGPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSEKAKLVSVLWKEAGTDVDTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     ESKINQAIADYQKKPSFHNSTVKTVLGQSTTVTDTNGLNLSEFDEVVENIANIDYRVN
                     GNQLVITPNANSKESGELTLKKSANTGTPVAYKMAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKETGNVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGAKVTIT
                     EKSVPAPYTIDTTPITATIKSGETISVTSKNTREKGQIILNKMGVETGTDLWNDKYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASNGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGNETQGKAEFKGAEYTL
                     FTAKDGQAVKWSEAFKPELVKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDNEKNAVITRDVTAKEQVIRFGFDFFKFAGSAAGTAETGF
                     NDLTFKVSPLEGTSEITDAEDEAITAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKADYTKSEYIFTITEKGQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLGTWKDGGKELTDLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     EATKAAQEKDEKAKPVVIAETTATLANKEKTGTWKILHKLTAEQVLDKTIVLFNYVYE
                     NKKPYEAGDDPVAKDASLNNQAQTVNCTVERHVSIQTKAHLEDGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDNTTKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYGKDGNINGKHNEDLKEKTQTLTPKKVPTTPSAPEQPEIPTVP
                     SDSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            5145..5459
                     /locus_tag="JOX41_001963"
     CDS             5145..5459
                     /locus_tag="JOX41_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAY6449689.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            5472..5846
                     /locus_tag="JOX41_001964"
     CDS             5472..5846
                     /locus_tag="JOX41_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAY6449690.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            5856..6200
                     /locus_tag="JOX41_001965"
     CDS             5856..6200
                     /locus_tag="JOX41_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HAY6449691.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDAEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            6271..7623
                     /locus_tag="JOX41_001966"
     CDS             6271..7623
                     /locus_tag="JOX41_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HAY6449692.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFWVALGRMSELGYS
                     MMFGEVDKKFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREISDIGGLNVNTEG
                     "
     gene            7683..8825
                     /locus_tag="JOX41_001967"
     CDS             7683..8825
                     /locus_tag="JOX41_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HAY6449693.1"
                     /translation="MTFLDLFAGIGGFCLGMEQAGHQCIGFCEIDDFARQSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     AAILQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQNRERI
                     FLIGHSRDACTEQVFPIIGSSPTSDQNIRNLLNINPSNRGMGGQVYGSDDVAPTLTGD
                     EGIKIALPVDDGISVAGMLLGNFEQGNRVYEITGTAPTLSTKQGGTKIMLRKNETEYQ
                     EVKPGNSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKEVKTDDL"
     gene            8850..9104
                     /locus_tag="JOX41_001968"
     CDS             8850..9104
                     /locus_tag="JOX41_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449694.1"
                     /translation="MIGKIQSDPELEEELYRLNFDIRKNGVKVPDDPYVIDEETDARM
                     ELNQVISELERIADFAKEPDIRQYLFEIKAELEIEGITAE"
     gene            9360..10544
                     /locus_tag="JOX41_001969"
     CDS             9360..10544
                     /locus_tag="JOX41_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAY6449695.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATTCGLSRPYLNQIENGGV
                     TASTKTMRKIFDQLESFNPELPLTLLFDYVRIRFPTTDARKIIQEILHLKFDYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKPDDKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNQKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVNNTRLSDRHKKILEQQSMAIENL
                     II"
     gene            10559..10678
                     /locus_tag="JOX41_001970"
     CDS             10559..10678
                     /locus_tag="JOX41_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HAY6449696.1"
                     /translation="MEIVKDILLVFGGSMLGVTVMCLMHASAAADRAMEKKGK"
     gene            10683..10904
                     /locus_tag="JOX41_001971"
     CDS             10683..10904
                     /locus_tag="JOX41_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449697.1"
                     /translation="MNFGQNLYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFLV
                     IALIAVGLVFNASGVKDVLLNLFNRIVGA"
     gene            10917..11417
                     /locus_tag="JOX41_001972"
     CDS             10917..11417
                     /locus_tag="JOX41_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAY6449698.1"
                     /translation="MEQIRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELKGTPIGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCNDMSDVAYYLIVEAGDLGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFELM"
     gene            11514..13361
                     /locus_tag="JOX41_001973"
     CDS             11514..13361
                     /locus_tag="JOX41_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HAY6449699.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEGLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMISDKVSIYSQKQIYEISKNQTSILELLDGYNSDLISEYKN
                     EIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIEDLKKQVEKLSHKSYKDVYDEYSKE
                     TDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGIKVTDEIDEHRGELIKNLVTNRAKI
                     QTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRYQRGIKNLVKSYLKMN"
     gene            13364..14260
                     /locus_tag="JOX41_001974"
     CDS             13364..14260
                     /locus_tag="JOX41_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAY6449700.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNFYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            14310..14699
                     /locus_tag="JOX41_001975"
     CDS             14310..14699
                     /locus_tag="JOX41_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAY6449701.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            14686..16188
                     /locus_tag="JOX41_001976"
                     /pseudo
     CDS             14686..16188
                     /locus_tag="JOX41_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP/GTP-binding protein"
     gene            16933..18759
                     /gene="ltrA"
                     /locus_tag="JOX41_001977"
     CDS             16933..18759
                     /gene="ltrA"
                     /locus_tag="JOX41_001977"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAY6449702.1"
                     /translation="MLKKNKLRYNEYYDMQHIYDELYAQSKNGNNFYKLLEIIGSEQN
                     ICLAYRNLKSNSGSKTAGTDGMTIDDIKQLSNAEIVATVRESLSNYRPKSVRRVFIPK
                     AGSDKMRPLGIPCIWDRLVQQCILQVLEPICEPKFHNHSYGFRANRSAHHAVSRVTTL
                     INLSKYHYCVDVDIKGFFDNVNHGKLLKQIWTLGIRDKRLICIISKMLKAEIDGEGVP
                     EKGTPQGGLLSPLLSLIVLNELDWWVSSQWETFQPKNRSKNGWLQYAKKYTKLKSGFI
                     VRYADDFKIMCSTYGEAQRFYHSTVDFLNKRLKLEISPEKSKVVNLKKNSSDFLGFKI
                     KVIPKGRTKHGYVAKTDMNQKALKKAKTNLKLKVKDIARHTTGFNISRYNLTVIGMQN
                     YYCIATNVYNNLTEVSYALLPTIRIRLRNIAKSVPFESTSSEFQSRTKGIRPKTKIVM
                     IADNPLLPIQGVQHKNPMNFSQDICNFTKQGRNKVHEDVVVVTKEEIRALLENENPAD
                     SVEFNDNRISAYIAQQGNCYVMNRRGTPSTLICIHKSDKGDNLDRYSNLAFVEIPIAK
                     AILTESADEAKSLLKGYVLNSQQKKKLNRIRTNYGYQTITGK"
     gene            18893..>19694
                     /locus_tag="JOX41_001978"
     CDS             18893..>19694
                     /locus_tag="JOX41_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAY6449703.1"
                     /translation="MPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSESLAIDILT
                     FLTGISSRDGEKFPVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIADHIESFTD
                     YDFAHLLFSDGSITQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVIS
                     TFALDFIHSNREIFKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDD
                     LLDERLKNNIGLKFAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLEN"
BASE COUNT         6655 a         3219 c         4308 g         5512 t
ORIGIN      
        1 gatatcaaac aaaaagtata catctttctt cattctagtt tttgcagcag ggattttaaa
       61 gtagttctta ttagaatagt agagattgat taataagcta tcttcgattg ctagaaagaa
      121 aacttctgaa tcccacacct tataaaaatc tttgataaat ctattcgaag gatcaaattt
      181 aaaccataat tgtgtctcat taaaaagcat agccattact ccgatctatt tttaaactta
      241 gtttctacct ctaatatata tcgagttttt attttgcctt cagataatac tgtttctttt
      301 ttcgcaatta caggttggtt attttcggaa aaagctaata tagctaagat tgaaacatcc
      361 atctggaatt tatctttttt gctgctttgc tcataaaagt ctgcatattc atcactgata
      421 ttttttctaa taaagtcttc catcataaaa atcacctcaa aacgattata cgaacttacg
      481 ttctcgttgt aaagcgatat ttgaggggca aaaagggggc aaaaatacgt ttacctttga
      541 tatatctcag attgaacata gtgtttatta tatgtcggta ttgttgattt atagctgttt
      601 tgagggtatt agatacataa tagaatatag tggttttgtt tacgtgcatt acacggaaaa
      661 gctgctcgta tcaaagaaat cagaagataa acacggaaaa cttccttgga aatctgaaat
      721 ttgtgaaaag tccttgtata tcaagggctt tttctttttt ctctatcaca gttttaagcc
      781 atttttggct gttttggacc atttttcaat catattccct taaaaattgt cctagattgt
      841 ccgacattga ctatcagtgt cgtcaaaata gggcaaaatt tagtagtcag cttgacgaca
      901 aatataatac gaaaaatacc aaaacattta ccgaatttag caacttttga acccaagttt
      961 ctcaaagggt cagctattag caaaaaagac aaaacatgta cttttctact aaaaagttga
     1021 tgtgataggc ttctatctaa ataactatta ggagttttta tcgtgaagca aaatgatgga
     1081 cgtatcattt ggaaaaatca aagtgagtta aaactgattt taacaattaa tgaattcatc
     1141 gaaaaacacg gaattacatc tagccgtcaa taccagaaaa agctatcaga aaatccaaat
     1201 tctgcaccaa gtatgtggtt cattaacaaa aaatatggat catgggagaa tttattgatt
     1261 agtataggac gagaaaatac tgggtatgga aaatgggcta gaatgtcaga acaagaatta
     1321 ttggaaatag tagaagcctt tattaagtgc gagaagataa cctctcaacg aatgtacgaa
     1381 caaaaatcag tagggaagaa tattccttca cttagtacca ttaaaaagat gttaggagat
     1441 atacgtccac tttttaaaga aaaaaatgat ggatctcgat ttactgattt cgaactgctg
     1501 ttagaactaa aaaatgaaat aatccgatta aaactacagg atgatttatc aatgacaaag
     1561 tttcgaaaac tagttcaatc cccaaaacta ccatcagttg atacaattat gaaaagaacg
     1621 aacaaaaatt gggaggaatt gatggcagag attggatttg attatcgaag aatcaaaatt
     1681 tataagcaga gaaacaacct atccaagaca aagaaaacta aatagtatca ctctaaatca
     1741 gacgttcaaa attaaaattt ggacgtcttt tttattaccc aaaaacgaaa ggagatttat
     1801 tttatgaaaa agccaagatt taagaattgg cgtttgctcg caacactgag tctattatgc
     1861 caaacaattg gtggatcgct tggcccaacg attgcctttg ctgatgaaat tactcatcca
     1921 caaacggtaa ctgtggaatt ggatttggct caccagtatg ctgtcgaagg tacatttagc
     1981 gatggtcgtc ccatgtcaga agttaccgtt ccgcactatg cagtttacaa tggtgtgaag
     2041 caagatattt tctgtattga gccaggggtg ccgatttaca atgagttcac tcctggttat
     2101 gagaaaaatc cattgcctga tatgtcggag aaagcgaaat tagtttccgt tttatggaag
     2161 gaagctggta cggatgtgga tacacatatt gtggcccaga agatgatttg gcaagaagtt
     2221 aatggctaca cgcttcactc aattaaacgt tctgatggta gtgcagtaaa tatcgcagcc
     2281 attgagtcaa aaatcaatca agccattgcg gattatcaaa agaaaccaag cttccataac
     2341 tccacagtga aaaccgtgtt aggtcaatcg actactgtga cagatacgaa cggcttgaat
     2401 ttatcggagt ttgatgaagt tgtcgagaat atcgcaaata ttgattatcg tgtgaacggc
     2461 aatcaactag tgattactcc aaatgccaat tcaaaagaga gtggtgaatt aaccctaaag
     2521 aagtcagcta atacaggaac accggtagct tataaaatgg ctggtcaaca aactttgatg
     2581 gcgggggcaa ttgataagcc caatacctac acaatcaaaa ttgatgtgga aactgagggt
     2641 tctttgaaga ttaaaaaagt cgataaagaa acaggaaatg ttgtaccggg aaccgttttc
     2701 catttagact ttggaaaaac attacctgca aaagacgtga ccaccgataa agaaggcatt
     2761 gcgacattgg atgagattcc tcatggcgcg aaagtaacca ttactgaaaa atcagtgcca
     2821 gctccttata cgattgacac tacaccaatc accgcaacca ttaaatctgg tgagactatt
     2881 tctgtgactt caaaaaatac tcgcgaaaaa ggtcaaatca ttttgaataa aatgggggtg
     2941 gaaacaggaa ctgatctttg gaacgacaaa tactcattag ccggaaatac gtttgccatt
     3001 cgcaaagaca gtccaaccgg tgaaattgtc caagaaatga ccacggatga aaaaggtcat
     3061 gcggaaacac caaaagagat tgccaatgcg ttggaattgg gaacctatta tgtgaccgaa
     3121 accaaagcta gtaatggctt tgtgaatacc tttaaaccag taaaagtcga attgaactat
     3181 gtcaatcaaa ccgtggctct tgttaccagt aacgtaaaag ggcaaaacca agaaatcact
     3241 ggtgaaacca ctttgacaaa agaagacaaa gataccggta atgaaactca aggtaaagct
     3301 gagtttaaag gagctgaata tactctcttt actgcaaaag atggtcaagc ggtcaaatgg
     3361 agtgaggctt ttaaaccaga gttagtgaag ggaacgaaag cttctgatga aacggtgact
     3421 ttgactttag atgaaaagaa tcaagttgct gttaaacact tagcgattaa tgagtattac
     3481 tggcaagaaa ccaaagcacc tgaaggatat accttggatg aaacaaagta ccctgtttcc
     3541 atcaaaaagg tggatgataa cgaaaaaaat gccgtgatta cccgagatgt tacggcaaaa
     3601 gaacaagtca ttcgctttgg ctttgatttc tttaaatttg ctggatcagc tgctgggact
     3661 gccgaaactg gcttcaatga tctgaccttt aaagtatcgc cattggaagg aaccagtgag
     3721 attacagatg ccgaagatga agcaattaca gcttataacg agcaactagg ttttgatggc
     3781 tatggcaagt ttgaaaatct tccttatggg gattatttac ttgaagaagt agaggctcca
     3841 gaaggatttc aaaaaattac gccattagaa atccgttcta cttttaaaga aaataaagcg
     3901 gattacacta agagtgaata catttttacg attaccgaaa aaggacaaaa acaaccaatt
     3961 aaaacggtga ccgttcctta cgagaaactg acgaataaag cattttctgt tagcttgaat
     4021 cgtttgatgc tctatgattt acctgaagaa gaagatagct taacttctct tgggacttgg
     4081 aaagacggag gcaaagaatt gacagacctt gattctaccg agctagttga taaattgagc
     4141 tataacttgc atgaaatcaa agaagactgg tatgtggtag cgcaagccat tgatgtggaa
     4201 gcgacaaaag ctgcccaaga aaaagatgaa aaagccaaac cagtggtaat tgccgaaaca
     4261 accgcaacgt tggcgaataa agagaaaaca ggaacttgga aaattttgca taaattaacc
     4321 gcagaacaag ttttggataa aaccatcgtc ttattcaact atgtgtatga aaacaagaaa
     4381 ccctatgaag caggtgatga tccagtagcg aaagatgcta gcttgaacaa tcaagcccaa
     4441 actgtcaatt gtacggtgga acgccatgtt tccatccaaa caaaagccca cctagaagat
     4501 ggttcgcaaa cctttactca tggggatgtg gtggatatgt tcgatgatgt gtcgattacc
     4561 catgatgtac tggatggctc aaaagaagct tttgaaacaa ttctgtatgc attacttccg
     4621 gataatacga ccaaagaaat ttggaaatct ggcaaaattg attatgaagt gaatgacaaa
     4681 gaattcacta aaaccgtact tgcggaaaaa gtggacacaa gtaaatatcc agaaggtaca
     4741 agttttacct tcaaagaaat taactatggc aaagacggaa acatcaatgg gaaacacaat
     4801 gaggatctaa aagaaaaaac tcaaacttta acacctaaaa aagttccgac aacaccaagt
     4861 gcaccagaac aaccggaaat accaactgtt ccaagtgact ctcaagaatc tagtcctaca
     4921 gtaaagacat tcccacaaac aggggagaaa aattctaatg ttctgctgtt tattgggttt
     4981 accttgatct ttgcgactgc tgggtattat ttctggaatc gccgaaacta aggtgatgtg
     5041 atgaaacaac taaataggaa aaaccaacgt gcgcgaccgc ctcctaaaaa aagtggtcgc
     5101 gctatttttg tatccaaaac taaaaatgaa aagaggaaaa gaagatggaa ttgaaatttg
     5161 ttgtgccaga tatggccgaa acctttggaa agataaggta tgccggcgaa ggcgaagttt
     5221 taactgaagg atatgggcgg aatactacag taattggtcg tagttatcat ttgtattcca
     5281 gtaagcaacg agccgatgat attgaagtgg tggtagctgc ggaagccggc gaaaaggatt
     5341 ttgatcaaga tcaaccacta aaagccgtga atccccattt ggttgccaaa ggctatgaga
     5401 ttgagaatcg tgggtttacc gactacgtgt tgtatgtcga tgatttagtg aaagcatagg
     5461 aggaaaagaa gatgagatta acagaaggta ttgttgtaga ttcaggacta acgtttggga
     5521 aattacgatt ttccgcatta cgccgagaag tacggaagca aaatgaggat ggaacggtta
     5581 gtaacgaggt aaaagaacgg acttataatt tgaaatcctc tgcgcaaggt cgaatgatcc
     5641 aagttagtat cccagcaaat gtacccttac gcgagtttgc ctatgacgca gaggtagagt
     5701 tggtcaatcc aatcatggat acggtcgcca attatgtttt ccgagaagga actactgtca
     5761 attggttcat taaggccgat gatttagtct tgaaacgaca accagatcag ggaaattcta
     5821 caaaccaaaa tgaaggaaag aaataggtga agcgtatgga aattaatgtt gaacatattt
     5881 tagattgtct cgatcaatat ggaaaaggtg agctaacgga ggaacaactc actaaagcat
     5941 taacctatga tgaaaaaatg tttctgatta tgcatcaagg gttactggaa gtaggtaacg
     6001 atgccgaaga agattttgat gtactgaatt ggttagggga agaagagtcc ttctttatgg
     6061 ttatcgaagt aaatgaaagt ctatgtcgag aagccgaaac cgtattggaa gaaattggtg
     6121 tggaaatgcc ggatgccatt gaagtttttt taaagcaact agtggaaacg aaacaactcc
     6181 ctatagcagt aaatgactag cataactgct tgaaattgga tcaatgaaat cctatgaagc
     6241 ttttttcgat tggaggtgga aaccataaaa atgtacaaag ggcatcgtat acgggcagga
     6301 gatcagcact tggtttatca ctttgttctt ggctggctac tcgctctgtt catcggttgg
     6361 atgagcgtct tttattttca agagcttaga caatttgata tttctaagct atcactttct
     6421 actatagaaa tcgttcgttc tataaaagat ttaatctatt tgctaggaag tctcgttctt
     6481 tcaggaagca cgatgttgct ttatatacac ttttttcagg atcattggcg cagtttgtgg
     6541 catcgacaaa agctagcccg gatgattcta gaaaatcatt ggtacgaagt aaaacaaact
     6601 cagagtgaag gatttttcaa agacctcaat agtagtcgaa ccaaagagac aatcagttac
     6661 ttccccaaaa tctattaccg tatgaaggat ggtttacttt ctattcgcgt tcaaatttca
     6721 ctgggaaaat atcaagatca gcttttaaag ctggaaaaga agttagaaag tggtctatat
     6781 tgtgaactag tagaaaagga actcaaagac tcctatgtgg agtacacttt actgtatgat
     6841 ataattgcca atcgaattgg gatagacgaa gtagtggcag aaagtggggc tttgcgattg
     6901 atgaaaaatc aagtatgggc ttatgattct ttacctcata tgttaatcgc tggcggcaca
     6961 ggtggtggga agacttactt tttactcact atcatcgagg ctttattaaa atctgatgcc
     7021 gagctttttg ttcttgatcc caaaaatgcg gacttagccg atttaggtac ggtaatgcct
     7081 catgtctatt cccaaaagga ggaaatttct gcttgtgtgg aagatttcta tgagcgcatg
     7141 atgactcgta gcaaggcaat gaaagaaatg cccaactaca aaacaggaga gaattatgcg
     7201 tttcttggac ttccaccaaa ctttttaatc tttgatgaat acgtggttta tatggaaatg
     7261 ttaacgacga aggaaagtgc ggtgattttg aataagctca aacaaatcgt gatgttaggt
     7321 cgtcaatctg gtttctttct gattctagct tgtcaaagac cggatgcgaa atatttagga
     7381 gacgggattc gcgatcaatt taatttctgg gtggctttgg gtcgtatgag tgaactggga
     7441 tattccatga tgtttggcga ggttgataaa aaattcttta tgaagcgtat caaaggtcga
     7501 ggctatgtag atacgggagg gagtgtgatt agtgagtttt atacgccact tgtaccaaaa
     7561 ggatatgatt tcttaaggga aattagcgac attggtggat taaacgttaa tacggaagga
     7621 taaaataata gtatgtagcc taggagtgtc aagaatcctg ggcttttttt acgaggtgat
     7681 ttatgacatt tttagattta ttcgctggga ttggtggctt ttgcttaggt atggaacaag
     7741 cgggtcacca gtgtatcggc ttttgtgaaa ttgatgattt tgctcgccag agttataagg
     7801 caatccatga tacaagtaag gaggtggaaa tgcatgacat cacaagtgta tcagacgagt
     7861 ttattcaatc tctcggacca gtggatatcc tttgcggtgg atttccgtgc caagcttttt
     7921 caattgcggg aaagcggcaa ggattttccg atactcgagg tactttattc tttgaaatcg
     7981 ctcggttcgc cgctattctc caacctaagt ttttattcct tgagaacgtc cggggattac
     8041 tcaatcacga aggaggggct acgttcgaga cgatcctccg aacgctggat ggattggggt
     8101 atgatgtgga atggcaagtg cttaactcaa aggcctacgt tccccaaaac cgtgagcgga
     8161 tcttccttat cggacattct cgagacgcat gtaccgaaca agtatttcct atcattggat
     8221 cgtctccaac atctgatcaa aacatcagaa acttattaaa tatcaaccct tccaatcgag
     8281 gaatgggggg acaagtctat gggtcagatg acgtagcgcc taccttgacc ggtgatgaag
     8341 gaatcaaaat cgcattgccg gtagatgatg gaatttctgt agcgggtatg ttactgggaa
     8401 attttgaaca aggcaatcgg gtttatgaga taactggaac agcgcctact ttgtcaacga
     8461 aacaaggcgg aacgaagatc atgcttcgga aaaacgaaac agaatatcaa gaggtgaagc
     8521 cagggaacag tgtgaacctg gcttttccta attccacaag tcgtcgaggc cgtctgggaa
     8581 aacaaagtgt gcatacctta ttaacaggag accaacaagc agtcgtcacg gatcagtatc
     8641 aaattcgaaa gttaacacct agggagtgct ggcggcttca gggctttccg gactgggctt
     8701 ttgatcgagc ttctcaagtc aattcagata gtcagttgta taagcaggct ggaaattctg
     8761 taacagttcc ggtcattttt gatattgcta gaagattaaa ggaggtaaaa acagatgatt
     8821 tatgatgagt tgattgggga atctactggg tgattggcaa gattcagtca gatccggaat
     8881 tggaagaaga actgtaccgg ctcaattttg atattcgcaa aaacggggtg aaagtccctg
     8941 atgatccgta tgtaattgat gaggaaacgg atgctcgaat ggagctgaat caagtcatca
     9001 gtgaattgga acgaattgcg gactttgcta aagaacctga tatccgccaa tacttgtttg
     9061 agataaaagc agagttggaa attgagggta ttaccgcgga gtaacggcca aataaaccac
     9121 tgataggcac tgaccgcggg ggatttgcga agcagaaatc ctccgtggtg ctgtgcctgt
     9181 ttatggacgg cgttagccgg ccatgatgtc tcaccccccg tatctaacag gggggtacaa
     9241 aaacacaaaa aataagcaag caacgataag gaatggctgt cctatcaagg ataataagca
     9301 atttgtgtag atgttaactg atttgaaaaa gttaacacct taaatttgga ggtgagaact
     9361 tggcacaaag gaatttagat tatcggctat taaaagaccg gcgtaatgaa tatggcgttt
     9421 cacaaaataa attagctacg acttgtggac ttagtcgccc gtacttaaat cagatagaaa
     9481 atggtggcgt aaccgcatcg acaaaaacca tgaggaaaat ttttgaccaa ctggaaagtt
     9541 tcaatcccga gttaccttta acgttactgt ttgactatgt aaggattcgc tttcccacaa
     9601 cggatgcgag gaaaatcatt caagagattc tccatttgaa atttgattat atgctccacg
     9661 aagattacgc cttttactcc tatcaagaac aatatgttat gggagatatt gtggtgatgt
     9721 tgtcacatga agaagataaa ggcgtccttt tagaattaaa gggtcgtggt tgtcggcagt
     9781 ttgaaacttt tttactcgcc caaaagcgta gctggtatga ctttttcgaa gattgtctaa
     9841 aagccggtgg cgtgatgaaa cgcttagacc tggcaatcaa tgatcgagtt ggcctgttag
     9901 atattcctga tttaacgaaa aaatgtcaga aggaagaatg tatctccttg tttcgtacct
     9961 tcaaaagcta tcgttccggg gaactgttga aacctgatga taaagatggt atgggcaata
    10021 ctttgtatat tggcagtctt aagagtgagg tctatttctg tttgtacgaa aaagactatg
    10081 agcaatatat caagttaggg attcctttag accagaccga aacgaaaaat cgttttgaaa
    10141 tccgactgaa aaatgatcga gcttatcatg caattcaaga tttgttaaaa ggtcgcagta
    10201 ttgaaagtac cacattttcc attattaacc ggtacttgcg atttgcggat aaggtggaag
    10261 gcaaaaggcg aactaactgg cccttgaatg aacaatgggg gcgcttcatt ggacggaatc
    10321 agaaggaaat tcaattaact tctgaaccga agccttatac cattgaacga acgttgaact
    10381 ggcttggacg acaagtcgcc cctacgtgga agatggccaa ggagttggat cggttgaatc
    10441 agacaacgta cattcaggat atggtaaata atactcgact atcagaccgg cacaaaaaga
    10501 ttttggagca acaaagtatg gcaattgaaa atttgattat atgaaaagag gaatcgtgat
    10561 ggaaattgtg aaagatattt tattggtgtt tggtggcagt atgcttggtg ttactgtgat
    10621 gtgcttgatg catgcaagtg cagcggcgga ccgagcaatg gaaaagaaag gaaagtgatg
    10681 aaatgaattt cggtcaaaat ttgtatcaat ggtttttaac caatgctcaa tctttagtct
    10741 tactagcgat tgtggtcatt ggtttgtttt taggatttaa acgcgagttt tccaaactga
    10801 ttggcttctt ggtgattgct ttgattgcgg taggtctggt ctttaatgct tctggtgtga
    10861 aggatgtctt actcaatttg tttaaccgaa ttgtcggtgc ctgaggggga atcacaatgg
    10921 aacagatacg tgtttatatt gcgaaccttg gaaaatacaa tgaaggtgag ttggtggggg
    10981 catggtttac cccacccgtc gattttgatg aagtgaaaga acggattgga ttaaatgacg
    11041 aatatgaaga gtacgcaatt catgattatg aactgccttt tgagattgat gagtatacac
    11101 caattgagga aattaatcgg ttgtgtggtt tagcggaaga gcttaaagga acgccaattg
    11161 gtgaggtcgc ttcagagatt caacatgcct tcttcaattc tttcgaggaa atggtagagc
    11221 atgtggatga tatcatctat tatcccgatt gtaatgacat gagtgatgta gcgtattact
    11281 tgattgtaga agctggtgat ttaggcgaag taccagaaca cttgaagacg tatattgatt
    11341 ttgatgcgtg tggtcgagac ttggagattg gcgggaatta tttggttacg agtcgagggg
    11401 tttttgaact aatgtaaatc atttgttaga attgaccaga aatttctatc gtacttttac
    11461 ttttctattt gatatactga aatagaaaat atttgttgat aggggtgtta ctaatggttg
    11521 gcaataagtg gtacaaatgt gatcttcata ttcattcaac tgcgagtcag tgctttcagg
    11581 ataaaaaggt tactgctaag gaatgggtag aagaatgttt aaacaaagga ctcgattgtg
    11641 ttgcattaac tgatcacaat acaggggaaa atattgatga atataagaaa gtggctatcg
    11701 aaaatggctt agattttttt cctggagtgg aattaacgtg tggagaaaat ggaactcatt
    11761 tactagtcct atttgataaa agtgcatgta caaatgatat ctctgatttc ttaaccaaga
    11821 tgggtataaa aagagaggat tgggccagcg ctgcagcttg ctcaatgaaa tcagttttag
    11881 aagttattga ttttgctgag cacgagggct tgctcgttat tcctgcacat atagatgagt
    11941 ttaatggaat ttcttcagca aaatttggaa atctaggaaa gatatttgaa tcagaaaata
    12001 tatatgcagt acagacggtt caaaaagaat tttttgaaaa tcgctcacaa atgattccct
    12061 catctaagcg tgacactatc tatgatagtg tgaatgccag atatgatggt agagttggaa
    12121 aagatacttt ggaatcttgg tataaatcag ttgttgaggc agaaaaaaat aatatgacat
    12181 ttcttagctt ttctgataac ccacactcga aaggaaattc aaaacatgga ctttggggaa
    12241 taggcacaag atattcctat ataaaaatga aggacgaacc tgacttggga tcacttcgcg
    12301 atgctttaat gctaggcgaa actcgagttc attctgattt ttctaatttc tccattaatg
    12361 aaaatgaagt tttattggaa aaattaagct tttctgggac cactcttagc acaaaagaag
    12421 ttgtagtcga attcagcgat aatttaactt caattattgg aggaagagga acaggcaaat
    12481 cttgtattac aagattcttg gtctatgtcc ttggaaagga agcagaactt gatcaatttt
    12541 ctgaaataca aagtgattat cagaactttg cacaaattga acataatggc tctggaatat
    12601 ttttgaagga tacaattgtg aaactgaata ttttctataa ggggacaaaa tatcaaataa
    12661 taagaacaca ggatagacat tctatttatg aatttacaca agagaatggt ctggttgaaa
    12721 aagaaacaga acggttgaga atgatttccg ataaggtgag tatatactct caaaaacaaa
    12781 tttatgaaat ttcaaaaaat caaactagta tactagaatt actagatgga tataactctg
    12841 atttgatttc agagtataaa aatgagattg aaacatgtgt aaacgaaata agaaaattaa
    12901 attgggatat tgtttctgtg aaaaaagaaa tacaagataa ggcgaaggta gagcttgaaa
    12961 ttgaagattt aaaaaaacaa gtagaaaagc tatctcataa gagttataaa gatgtttatg
    13021 atgagtattc aaaagagaca gatatttata gggaactgaa acgtgatgtg gaggcactta
    13081 aggaaattcc caaaaatcta actgatagtg ttgacaaaat tgactttggc aatggtataa
    13141 aagttacaga cgaaattgat gaacaccgcg gagaattgat taagaattta gtgaccaatc
    13201 gggctaagat tcaaacaata attaatgaaa tgtcagatga aattgatagt tatagagcag
    13261 agctgaataa atcagattgg aaagttaact ataatgaggt ttcaaagagg tatcaaagag
    13321 gtatcaaaaa cttagtgaag agttatctca agatgaatta aaaatgttac aaaaccttga
    13381 ttctttatat caatctttat caaaaactga agagcgattg gaagaaatta ttcaacaaga
    13441 aataaagctt aaagattacc aagttgaggt tgactcagca atgtcaagaa tgaataaatc
    13501 atatcaaaat ttctattctg agagaagtag ttcctcgcgc gaaatttttt ctgatattac
    13561 aggaatagag gctactattc aaccaaatag ggatttcaat aattatgtta aagagctcag
    13621 agcttgtatt aataaggagg acacttttga cagtgagttt ggatctctta ttgataagct
    13681 gacaaaaaat tccattacta atcaagatat atataatgac atacttgata taagagttag
    13741 tggggaaagt agtatttttt cagataaaaa attaatcaat tctataagaa aattgaatga
    13801 tgcacaagtt cttgaattac aaacccttaa gccaaatgat ttagtagtta tccgacttga
    13861 actaaatgga aaaaaagtta gtttatcgaa tgctagtgct ggtcaaaaga catctgcaat
    13921 tctttctatg attttggcgt atggaaattc accactcata ttggatcagc ctgaagatga
    13981 tttggatagt caattaatta ataacttaat cgtaagaagt atcattacaa aaaaggaaaa
    14041 cagacaaatt ttaattgtaa ctcataatgc aaatatccca gttaatggtg attcagaatg
    14101 gttgattagc atgggagatt caaaagaaat atcggctgat cagtgcgggt cggtagatga
    14161 acccaatatc aagccaagaa tatgtactgt gatggaaggt ggcgaggatg cttttacaaa
    14221 tagagcgaaa cgctatggtt ttaaacaaat tgtagaataa cactagaggg tgagacatat
    14281 tattatgtcc gcccttttta ggaggaaaaa tgaaaaaaat aaaaagctat accagtatct
    14341 gggcagttga aaaagtcatt tacgcaatca atgattttca gttgcctttt cctgtgactt
    14401 ttaaccaaat ggcttggttc gttttatctt tactgtttgt catcgtattt gcccatgtgc
    14461 ctccactatc tatgatagag gaggtctttt taaaatactt aggcataccg gtggctgtca
    14521 cttggtttat gtcgcaaaag acgtttgatg gcaagaaacc actgggattt ttacgatcct
    14581 ttatcagcta tcacttgcga tttaaggtga cttttgcagg aaagaaagtc aaagaacaga
    14641 agaaacgatg ggatgaaccc agtactcttg taaggagtgt gaactatgta tccgattaag
    14701 tatattgaaa ataatctcgt ctttaaccaa gaaggcgagt gttttgccta ctatgaatta
    14761 gtgccttaca attactcctt tttgtcaccc gaacagaaat ttcaagtgca tgataacttt
    14821 cgccaactaa ttgcgcaaaa tcgtgaaggc aagatccatg cgttacaaat tgccacagaa
    14881 agtagtattc gcgccacaca agaacgatca aaaaaagaaa ttaccggtag actcaaagaa
    14941 gtagcgaaac aacgaattga tatacagaca gatgcattag tatccatgat tggcgatagt
    15001 cagattgatt atcgcttttt tattggcttt aaactaattg cgacagatga agaagtcaat
    15061 ctaaagagtc tcaagaaatc tttcttttct gggcttcaag aatttgtcta tggagtgaat
    15121 catcatttga tgggcgattt tgtttcctta tccaatgaag aaattcgctg ctattctaag
    15181 cttgaaaaat taatggaaag caaattggct cgaagattta aagtcaggcg agtcacaccg
    15241 agtgacctga cgtatttgat tgaacatatt tatggcgaaa aagggatacc gtttgaagaa
    15301 tacgaatttc agctaccaaa gaaaaagcta aaatcagaaa cactggtgaa acgttatgac
    15361 ttattacgtc caaatcgttg tttaattgaa gaaaaaccaa ggtgcttacg gatggaacat
    15421 gagaatcatg agtcgtacgt agcgtattta acaattaata caattgtggg ggagatggaa
    15481 tttccttcct cagaactttt ctattaccag caacaacaat ttacattccc aatcgacaca
    15541 agtatgaatg tagagattgt gacgaataaa aaggctttag ctaccgttcg taataagaaa
    15601 aaagaactga aagatttaga caatcatgct taccaatctg acaatgaaac gaattccaat
    15661 gtcttagatg ctttggattc cgtggatgaa ttggaaacca ccttggatca gtcaaaagaa
    15721 tctatgtaca aactgagtta tgtggttcga gtgagtgccg aatcagtgga tgaactaaag
    15781 cgacgctgtg atgaagtgct cgatttttat gatgatacca atgtaaaact agtccggccc
    15841 tttggcgata tgatggggct acatgaagaa ttcttaccct taagtaaacg atatatgaac
    15901 gactatattc agtatgttac gtctgatttt ttggcggggc ttggttttgg ggctactcag
    15961 atgctaggag aattagaagg gatttacttt ggctacaatg tggatacagg tcgtaatgtt
    16021 tacctgaaac cggcattggc ttcacaagga gtcaagggtt cagtaaccaa tgcgctggcc
    16081 gccgctttcc tgggttctct tggtggaggt aaatccttta gtaacaatct cttagtctac
    16141 tatgctgttt tgttcggtgg tcaagctgtg attgtcgatc caaaaggggg tgcgaaacgt
    16201 tcctacttga aaagagtagg cacagcactt cattaaatca atatttaatg tgtgttggag
    16261 aactaaacac acgaatagtc gaatgacggg gtaacgccct gaaaggctac tttaatactc
    16321 tgactggcag aaacttgagt aaacaaggct ctgtcagaag ctcggtgaag tcggcagaca
    16381 gacaccgtaa cagataatgc tgacgaaaga ttcccagagg tgggcgttgt gtcctatatg
    16441 ccggaagtct ataaaatatc tatggttaga atgtagatga gaggtctact gacgaatcct
    16501 tgaatgtaca ggtctatatc ggggctggat agaaatgtcc agtgacacaa acagtgtcgc
    16561 tactgtgggt gagtaagact ccgcatttat gaaaatccat ataacgttaa aggcgttatc
    16621 aaggtagcag gcttatagag gaaacctaag gatatatgta cagatagtgt gtttggaacg
    16681 ttgaaagctg acaacatgga gattttactg tctgtgaagt gttcacatca gaaagttatt
    16741 gtgagattag caatgatata aggtgtgtta atgtcagtga gagtggtggc acagtaccta
    16801 tgaaaccgtg ataacaagcg gtggagggat agccactagt catatgaaga atagaattac
    16861 taagaaaaat ggtatgggtt cgagtaagac taagagatgt acttgctcct gcaaacaagg
    16921 agggtacaga ccatgctaaa gaaaaacaag ctccgctata acgagtatta tgatatgcaa
    16981 catatttatg acgagttata cgcacagagc aagaacggta ataactttta taagttactt
    17041 gaaattattg gttcggaaca aaatatttgt ttagcttacc gtaatctgaa atcaaacagt
    17101 ggcagtaaaa cggctggaac ggatggaatg acgatagacg atataaaaca actcagcaat
    17161 gctgagattg ttgctaccgt tcgggaaagc cttagcaact accgccccaa atcagtcaga
    17221 cgtgttttca ttccaaaagc tgggagcgat aaaatgcgtc cattggggat tccgtgtatc
    17281 tgggacaggc tggtacaaca atgtatcctg caagtcctag agccgatatg cgaaccaaag
    17341 ttccataatc attcctatgg attccgtgcg aatcgaagtg cccaccatgc agtcagcaga
    17401 gtaacgacac tgataaattt atcaaaatat cattactgtg ttgacgtaga cattaaagga
    17461 tttttcgata atgtcaatca tggaaaacta ttaaaacaaa tctggacact tggtattcgg
    17521 gataaaagat tgatttgcat tatcagcaaa atgctgaaag ccgaaattga cggcgagggt
    17581 gtcccagaaa aaggaacgcc acaaggcggt ctgttaagtc cactgctctc cctcatagtc
    17641 cttaatgaat tagactggtg ggtaagcagt cagtgggaaa cattccagcc gaagaaccgc
    17701 agtaaaaatg ggtggcttca atacgcaaag aaatatacca aactgaaaag cggttttatt
    17761 gtacgttacg ctgatgattt taaaatcatg tgttcaacct atggagaagc acaaagattt
    17821 taccacagta ccgtagattt tcttaataaa aggctgaaat tagaaatcag tccagagaaa
    17881 tcaaaggtag taaatctgaa gaaaaattca tcagattttc tggggttcaa aatcaaagtc
    17941 attccaaaag gaagaacgaa acacggttat gttgccaaaa cagatatgaa ccaaaaagca
    18001 ttaaagaaag cgaaaacaaa tctaaagtta aaggtaaaag atatagccag acatacgact
    18061 ggcttcaata tcagcagata taatctgaca gttatcggta tgcagaatta ctactgcata
    18121 gcaactaacg tatataacaa cctgacagaa gtaagttacg ctctcttacc gaccatacga
    18181 atccgtttaa ggaacattgc aaaatcagtt ccatttgaaa gtacaagttc agaatttcag
    18241 agcaggacaa aaggaatcag accaaaaaca aaaatagtga tgattgcgga taatccgcta
    18301 ttgccgattc aaggagtaca acacaaaaat cctatgaatt tctcgcaaga tatttgtaat
    18361 tttacaaagc aagggagaaa caaggtgcat gaggacgttg tagttgtaac aaaagaagaa
    18421 atccgagcgt tgttggaaaa tgaaaaccct gccgatagcg tagagtttaa cgacaatcgt
    18481 atttcggcat atatcgcaca acaaggcaac tgctatgtaa tgaatcgtcg aggaactccg
    18541 tccactctga tatgtattca caaatcagac aaaggagata accttgacag atattctaat
    18601 ctggcatttg tggaaattcc cattgcaaag gcaatcctaa cagaatcagc agacgaagca
    18661 aaatcactgt taaaaggtta tgttcttaat agtcagcaga agaaaaaact gaacagaata
    18721 cggacgaatt acggatacca gacaataact gggaaataac ttataaatct atttggatat
    18781 gatggaacgc cgtatgaagc gaaagtttca tgtacggtgt gaagcggggg aaaacttgga
    18841 gataacatca aaaagttacc tatcgctata gcgaggaggg tggaaagaaa ccttgccaga
    18901 aattgcggat gaaatcagta tcctcaactt gacgagtaag tcagaaaatc aaggtctgct
    18961 tgatccttat gtgattatga agaaaaagaa agactcggaa agtttagcaa ttgatattct
    19021 gactttttta acaggaattt caagtcgaga cggggagaag tttcctgtgt tacgtaaagc
    19081 cattcgaacg gtgactcaaa gtgatcaacg ggggttatta caagttatta acgaattgcg
    19141 aaaagacggg tcaccaatcg cggaaaatat cgccgatcat atcgagtcct ttaccgatta
    19201 tgattttgct catttgcttt tctcagacgg ctcgattacc caatcgatta gtttagataa
    19261 acagctaaat atcattcaag tggcggattt ggttttaccg gatgcagaaa cgacttttga
    19321 agaatatacc accatggaat tgcttagtgt ttcgatgcta atcgtcattt ccacttttgc
    19381 cttggacttt atccatagta accgagaaat cttcaaaatt gtcgatttgg atgaggcttg
    19441 gagttttctt caagtggctc aaggaaaaac gttatcgaat aagcttgttc gtgctggtcg
    19501 ggccatgaat gctggggtct atttcgtcac tcaaaatagc gacgatttat tagatgaacg
    19561 tttaaaaaat aatatcgggt tgaagtttgc ttttcgcagt accgatattc atgaaatcaa
    19621 gaaaaccttg gaattctttg gtttggatca ggaggatcaa agcaatcaaa aacgcctgcg
    19681 agatttggaa aacg
//
LOCUS       DADLIO010000051        17727 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.052, whole genome shotgun sequence.
ACCESSION   DADLIO010000051 DADLIO010000000
VERSION     DADLIO010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17727)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17727)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17727
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.052"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            68..1219
                     /locus_tag="JOX41_001979"
     CDS             68..1219
                     /locus_tag="JOX41_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAY6449704.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(1328..3370)
                     /locus_tag="JOX41_001980"
     CDS             complement(1328..3370)
                     /locus_tag="JOX41_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HAY6449705.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKIAFDSLGGKAASTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFKTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADDKETKDKKNVISETAVQTIVSDLREVVQDVNGTAHSLSALGIPLAAKTGTAE
                     IKEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(3428..3985)
                     /locus_tag="JOX41_001981"
                     /pseudo
     CDS             complement(3428..3985)
                     /locus_tag="JOX41_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     gene            complement(4524..4730)
                     /locus_tag="JOX41_001982"
     CDS             complement(4524..4730)
                     /locus_tag="JOX41_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449706.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(4746..5360)
                     /locus_tag="JOX41_001983"
     CDS             complement(4746..5360)
                     /locus_tag="JOX41_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HAY6449707.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(5507..6190)
                     /locus_tag="JOX41_001984"
     CDS             complement(5507..6190)
                     /locus_tag="JOX41_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HAY6449708.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(6299..6757)
                     /locus_tag="JOX41_001985"
     CDS             complement(6299..6757)
                     /locus_tag="JOX41_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HAY6449709.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(6841..8604)
                     /locus_tag="JOX41_001986"
     CDS             complement(6841..8604)
                     /locus_tag="JOX41_001986"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HAY6449710.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(8825..10285)
                     /locus_tag="JOX41_001987"
     CDS             complement(8825..10285)
                     /locus_tag="JOX41_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449711.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(10493..11419)
                     /gene="glsA"
                     /locus_tag="JOX41_001988"
     CDS             complement(10493..11419)
                     /gene="glsA"
                     /locus_tag="JOX41_001988"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HAY6449712.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(11442..12869)
                     /locus_tag="JOX41_001989"
     CDS             complement(11442..12869)
                     /locus_tag="JOX41_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAY6449713.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(12900..14114)
                     /locus_tag="JOX41_001990"
     CDS             complement(12900..14114)
                     /locus_tag="JOX41_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HAY6449714.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            14464..15543
                     /locus_tag="JOX41_001991"
     CDS             14464..15543
                     /locus_tag="JOX41_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006908283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAY6449715.1"
                     /translation="MTQNHDNTVSRKGKHLTYSERCQIAILKKENYSNRQVADVLGCV
                     PQTINNEIKRGTVTQLNRQNQNGKVYDYYHDVYDADAGQAAYEKNRLNCGRRPLWADT
                     DAFIEWADDMMLLEKWSPDVVVGFARKHELFDPAIIPGTTTLYQWIDRGIMKTKNMDL
                     LEKLSRKPKSSRHGNRPNKRVLGKSIEERPEAVGTRKTFGHWEVDTVVGNKTKSDAVL
                     LTLVERQTRFEVILKLAGKDAESVNQAVRQLRERAGAYFGQLFKTVTSDNGSEFAGLH
                     DALQDVANIYFSHPYASWERGTSENQHKLIRRFIPKGSPIGNVSENQILRIQRWMNDY
                     PRKILGYATPHDTFVQAFRQERLTA"
     gene            complement(15844..16086)
                     /locus_tag="JOX41_001992"
     CDS             complement(15844..16086)
                     /locus_tag="JOX41_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAY6449716.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(16118..16675)
                     /locus_tag="JOX41_001993"
     CDS             complement(16118..16675)
                     /locus_tag="JOX41_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAY6449717.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(16688..16876)
                     /locus_tag="JOX41_001994"
     CDS             complement(16688..16876)
                     /locus_tag="JOX41_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HAY6449718.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(16889..17455)
                     /gene="amaP"
                     /locus_tag="JOX41_001995"
     CDS             complement(16889..17455)
                     /gene="amaP"
                     /locus_tag="JOX41_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HAY6449719.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
BASE COUNT         5027 a         3685 c         3135 g         5880 t
ORIGIN      
        1 tcctattttt tcaataatgt atgttatgct aagttcgggc tatattttat acaaaggaat
       61 gatgagaatg gaatttattg gtattttatg cctgatattg atttcaacaa cgattggctc
      121 acatatctcg cggagattag gtatcccagc agtgattgga caattacttg ttggtgtttt
      181 gctaggccaa gctggattga attgggtcaa acctgatatt ctagtccatg acttttcgga
      241 gattggtgtg atcttattaa tgtttttagc tggtctggaa agtgatttat ctcttttgaa
      301 aaaatatttc cgacctggta tgttcgttgc tttgcttggg atcatcttcc cggttgtttt
      361 tggctggttg acaggcaaag cattccaagt ttcgggaaat gaagcgattt tctttgggat
      421 tattcttgcg gcaacttctg tcagtatttc agtagaagta ttaaaagaac taaacgtagt
      481 gaatacaaaa gaaggatcaa caattttggg tgcttctgtg gtagatgaca ttttagtcgt
      541 tttagttcta agtttcagcc tatcttttct aacgggggaa gcttctagca atgcttcttt
      601 accgcttgtt ttgattgaac agctaattta ttttgttttt attttcttat tagtcaaatg
      661 gattgcgcct ttcctacttt catttgcaga aaaagtgtac gcaaattctt ctattatcat
      721 cgtatcgcta gttatttgtt taggaatgtc ttacgtagcg gatcttgttg ggcttagctc
      781 tgtcattggt gctttttttg ctgggatagc tgtcagtcag acaaaggtta aagaagaagt
      841 ataccacaat gtagaggctt taggatatgc agtatttata ccagtatttt ttgtcagtgt
      901 aggattagaa gttgattttt ctgactttag tgaacaacta ctctttattt ctatattgac
      961 gcttgtagcg attttgacca aattgcttgg aggttatttt ggtgctcaga ttgccggttt
     1021 ttctcaacat agttcattga tggtcggtgc tggtatgatt tcgcgtggag aaatggcttt
     1081 gatcatttta caaattggac agcaaagtca attgatcgaa ccacagtact attcaccttt
     1141 agttatcgtg attttattaa gtacacttat ttctccactt gttctcaaat attttacaaa
     1201 aaaagtttat gaagtgtgag taaatcaaaa agaagttgtg aaagagacat cgtgaaaacc
     1261 gtttatttga aaaaaggact gtgacgataa cgccacagtc cttttactgt acttaaaaag
     1321 caatttttta ttgataattt tggttgaggt attgcaatag ttccgatgct cgtttggttg
     1381 ctgaatcatc atcttcttta ttttccaaca tgctgaccat catataacct tggttatcaa
     1441 gattgaaagc aaacaagaaa ctgttctctt gcccctttac atcctgtttt tctttgattt
     1501 ccgctgtacc agttttcgct gccaacggaa tccctaaagc agaaagagaa tgtgctgtac
     1561 catttacatc ttgcacaact tctctcagat ctgacacgat cgtttgtact gctgtttcgc
     1621 tgatgacatt cttcttatct tttgtctctt tatcatctgc aatcaattta ggatagacaa
     1681 gtgtgccatt gttggtaaaa acagaataca ttgctgcttg ctggatagga gtaattagaa
     1741 gttcgccctg tccatatcca gtatcagcta gcaagatatc tgagttaaag ctatcttcat
     1801 tagaaatttg tgctggattc atactaattg gcaaatcaag gtcttcacca aaaatgaatt
     1861 tatctaagcc tgtacgaaat tttttctcac ccattttcaa cgtttcttgt gccgcatata
     1921 tattatcgga atagatcaaa gcagttttta agtctacttg tgatacatca ctactgacac
     1981 gcgttgtttt aaaagatccc caagaactgt ctttttgcca tttaagcccg ttgatcgtca
     2041 acacttcatt tggatcgata gtgccgttgt cgagaccgat tgctgctgta atcattttaa
     2101 acgtagatcc aggagcataa cctgtcgcaa atcggctgat gaatggatgt tcaggatttt
     2161 cttcataagc tttgtaatct tcttgtgaga tcccgtttgt cattttgttt ggatcatagc
     2221 ttggagagct agcaagcgca agaagatcac cggtttttgg cgttgtcgca acagttgatg
     2281 cagcttttcc tcctagactg tcaaaagcta ttttttgtgc cttcgcatcg attgtcaatt
     2341 tgatatcttt gccattttga acttcatgtt cgatcagaac ttttttctct acaccgtctg
     2401 catctgtaat gcttaatttc ccacctgttg tcccacgaag atccttatca aaagccatct
     2461 ccaaacctga gcgaccgatt tttccattac tgcttaattc tggattctta tcaatatctt
     2521 ctgctgtgat atctcccacg taaccaatca gctgagcagc tgcttcaccc aaaggataat
     2581 atctgccgtc tacttcttga atggtagctc cagctggaag ttctggcgtt gctccatcaa
     2641 tgattttcaa tgggacaaag taatcgggtt gtacccagct ttgtgaaatc gcctgattga
     2701 tagcatcttc tgttaagtcg aaggaggaag caatcgcttt gatattggct gttttttcgc
     2761 ctccatctcc aagtttactt ggaacgactc ctaattgttt tagtttgcct gttgttgcta
     2821 atggttcacc atttcgatct ataatattcc ctcttgctgc ttcttgtgtg gtcaggctta
     2881 ctttgtcatt tccttccatt tctggaaaaa ccaagttggg ttgccagttg atcgtggttt
     2941 gaccatcatt tctgtctaat gttcctttat aagaaagatc tttcaattca cctaatgagg
     3001 tattcatctt tgctttatat gaaaaactgt aagtagaatc gtctttttta tctactttta
     3061 gattcgatat ctgaagtcct ttgacatcag cagcaccgta tatattctgg tatttatcta
     3121 agatctcttt ttcagataat gcacttttat ttgccgcctt ttttgatgtc atttctgcag
     3181 ctttgttata atctcccttg ttcaaagctt ggacaaattg ctcaactgtc ttttctccag
     3241 cttctactgc ttgggtttct tgatagtgct ggtagtaaaa ataaccgcca cccgcagctg
     3301 ctattaagat cactgcgccg gcaatataag cgcctgttcg atttttgccg tgcttgtcac
     3361 ttcttttcat tttttcctcc ttctcttgct tgtcattcct ttatttcact atttatacct
     3421 gtttattcta acatatgtct ttgaggaaat ccataccaca atccagaagc acactttctg
     3481 gaaggttcgt ttggatacta ccaagtaatt tcccaaccgc tttgggtagc ttgaatattg
     3541 aagttacgtc tttcagctgc tgagagatag ctttgatcac ttgctgctgc cttctgatcc
     3601 tcccgaagtc tccttctttg tcttcccgaa atcgagcata ctggagtaaa gtattaccat
     3661 ccatcacttg ctctcctttg tttatatata cgccatctaa atctagagat ttttctgcat
     3721 cgatcttgac tccaccagga aacagttcat taacgcaatc gataaaatct tgaaatgtga
     3781 tacttgcata atagggagct tcaaatttga aattttcctt taatgtttga tttaataaat
     3841 caactccccc ataagagtaa gctgcattta tcttattcat tccgtaacct ggaatatcga
     3901 catatgaatc tctcatgata gagatcagtt ttgcttgttg tgttttctgg ttgtattgtg
     3961 caaccagaag tgaatccgag cgacctccac caatcgatct tttttcaccg catctcctcc
     4021 tcacacagca atccacttgt caggtgagga gcgagtttgt ctcatcaaat aagtcagtca
     4081 caaaaatata aagaaaaggt cagaaacctt ttcgaacaag aattctgacc tagcatcatc
     4141 tcatcgtccg agttttagca ctatacaacg taaagaaaac attcttagct attggaaaaa
     4201 gccttaatcc aacagtttct gttttaccca ttggcgactt tcgacgtttc tgggcaacag
     4261 cctatgtttg tataggagcc tcacctaaca aggttattac tatattctat ttacgagttc
     4321 atgatagact tttcctaatg attaggcaat ggaatttgaa atgaaatagt gaaatttaac
     4381 aatctttaat attttttaga aaaaaataac aaataagttg aaagaatccc gttgcaaatt
     4441 ctttcagttg caccaggatt ctttgataat tttttagttt tatgtgtttt tttatatgtt
     4501 ttttcacttt tcggaataaa tatttatttg ttaaagtaat taaacaatcc gctaatcgtt
     4561 tgatctggca tttctatttc cttaccatct aaagtaacag tagtaacgac aaaatggtct
     4621 tgcaatggcg gaacttctaa gtactgccct tgcagaaaat cattcactgt ttcatattct
     4681 tttttcattt cttttgaatc tgtcgatggt ttatagctta tttttaacat aactagtgct
     4741 cctttttatt cgggacgtgc aatcgtgaaa atttctccta ttgctgcata atcatttcct
     4801 gccaaacggc ttacagcatt caattttctt ggatcgatcc ttcctgtctt atcatcatag
     4861 actgtttcat ttaaatgata tttctgtact tctagcaaaa ataaatcagc tgttacttta
     4921 tttttattcc gtatctcgac atgttcatat aaggatgttt caaaacgaac ttttgcttct
     4981 gtcaatgctg gtactgaaat gattactgaa tcagttaaag tcaagtcagt caggtacagt
     5041 tcgctttcct cattaggcag attggctgct gttttattta cttcttctac gttgtcctca
     5101 tcaaggatat ggataacagc ttctcttgtc tcaagaatat tctttgctgt gtcttttact
     5161 gcatcttgtt ttctctggat cgccaaggat aagatgggtc gattcgaact gacgatattg
     5221 aagtaactga agggtgcgat attcactata tcttttgctg atttagtcgt tactactgct
     5281 actggtctag ggatgactga accaatcagc aacttgtaat tttcacgttc tgtcaattct
     5341 gaaggactcc gttcaaacat ggtttcgcct tctttctata aaattcgtta aaaagcagat
     5401 cttgaagaca aaatgaaaag taatgctttt ttcatcttct tagaatctgc tttaaactat
     5461 ctatcaattt ttcttttttg tcaagaatct gtgccgtgcg tgttttttag ttatttgctt
     5521 tacttgcggc ttcgacatat cttttagtga tcaattgcgg acgggtgata atagatccaa
     5581 ctacgactga aaaagcacct aattcatatg ctttctctac ttgttcagga gagtcagtat
     5641 gtccttccat aattactggg atatcgactt gttctatgat ttgattcaat aaatcaaaat
     5701 caggtgtctg cgtctttcgt gaatattctg tatagcctgc taaagtcgta gacaaaagat
     5761 caaaaccatc ttcttgcgct tgaagcgctt cctcaaaagt cgaaatatct gccatagcta
     5821 accgaccgtg ttcgtgaatc atttggacaa gttcagcagt tgttttttct gtcggacgtt
     5881 tacgagaagt tgcatccagt gcaatgattt ctgcttgcgt ctccaaaagt tcttccactt
     5941 ctttttctgt cgcagtaata aacacttctg acccatcgta atctcttttg ataatcccta
     6001 ttaccggtaa atcaacgatt cgcttgattt cattgatatc ttctgtcgta tttgctcgaa
     6061 taccaactgc tccgccttct tttgcagcca aagccattct ccccataata aaagaactgt
     6121 gtagcggctc gttttccaaa gcttgacaag aaacgacgac tccgcctttg atttgttcca
     6181 gtgtatccac aatatctcct ccagtaatgt tatataaaaa tacagcttca tataaaaatg
     6241 taaccctttt ctattcagga gacaataatg agctatttct ttcagcagac ctttcttact
     6301 aaaagaaaat tacttcaaat tcttcgtata cgaccagctt ctcttctgta aattctatgt
     6361 tcaacgcttc tttataagca tgtttaaaaa actcagcatg gactttccgc caataagcta
     6421 atgtccgatc cccttctcct tctttccaag catgctcttt cgtgacttca ctaaaaggca
     6481 agatggtcac atttatattt ttgatgatac aaactggttc attttttcca ttcaggacca
     6541 cgtctaattg accaactttt ggtaaaggct cattctcttg tttatacaga tcgtaaccac
     6601 ttgatgtacc agtctttatc ttttttacaa ctagttcgct caactcgtct gccatttttt
     6661 ctgtatcccc aaatgaaaag aaacctaatt tttctgattg ataactagga tatttttctt
     6721 ggaacttttt gacatattct tctacttgct gatacataac atccacccct ttgcttttta
     6781 taatgaaaaa accatccaga tactagtata aacaattatc tggatggtga gcataatgaa
     6841 ttattgaata ttcaagacac gcagactatc ttcaacgatt tgttttggtg ttaaatgata
     6901 acgttcataa agctgcccta caggaacgct atccgtgaat tctttctctg caccaaaatt
     6961 taatacgttc attgaagaat caccataata acgactgata ttttcgccaa atcctcctga
     7021 caaactacca tcttctaatg tgatgactaa ttcgtgtgtt tcttttaatt tatctaatgt
     7081 ttctacgtca ttttctgtga tcgttcctgg attgatcaac gttgcttcga ttcctttttt
     7141 tctaaaagct tttactgttt cttttcctaa ttcaagaaaa ccgcctaaag ctaaaattgc
     7201 tacttttcct ccattattta ctgtttgata ggctggaata ctataatcat ttgcgatagc
     7261 tgtaccatgt tctacaccat gtgtaggaat tcggattgct acaggctgcg ctgtttgttc
     7321 gaacgcccaa tctagcatag agatcatatc ctcttttgtt gctggagcaa gatatttgat
     7381 gttcgggata cttgataagt aaggaatgtc aaatgttcct tggtgtgttc ggtcactagc
     7441 tgagatcgtt ccgccaccga ctaaaataat cactggattc tcgttgatcg ctaaatcatg
     7501 tgataattga tcatatgccc gttgcaagaa agtacttgat tggaagacga ctggacgtac
     7561 tccctgagaa gccaaagcag aagcgaaagt gatagagtgc tgttcagcga tccccacgtc
     7621 aaaataatga tctggatgtt tttcttggaa tgttttcagt ccaaaggcgc ctggtatcgc
     7681 tgcattgact gcggcaatag gagctgtact tgtttgcatt ttcttatcca aataatccat
     7741 gatgatcata ttaaatgttt ctccagaagt tacttgcttt gcctccccgg tggacagatc
     7801 aaatggtaca tgccaatgat atttcatttt attatcgatt gccggctgat aaccgcgacc
     7861 tttttccgta tggacgtgaa gtacaatcgg atgatcaata tcttttactt cttcaaataa
     7921 acggatcacc gtttccagat cgtttccatt atccacgtaa cgataatcaa atcccattgc
     7981 tttaaatagg ttattgctgc ttttaccgtt ggtttgacga agctcagcta agtttttata
     8041 taaactgcca tgattctcat caatagacat ctcattatcg tttactaata cgattagatt
     8101 ggattgtaaa acaccaccat tgttcaatcc ttcaaaagct aagccaccac ttagggagcc
     8161 gtcaccgata aatgctacca catttcctga ttctttcttc agatctctcg ctttagctaa
     8221 acctgttgct aagctgatag atgtagatgt gtgccccact gtaaaatagt catgtttact
     8281 ttcatgttgg ttggaatatc cgctcacttc acggtaatgt cctttttcaa aaccattttt
     8341 tcgaccagtt aaaagcttat gaccataaga ctgatgggaa acatcccaaa cgattttatc
     8401 ctttggtgaa tcaaatacat aatgaaacgc aatcgttaat tctactacac ctagattcgg
     8461 accaacgtgc ccacctacat cgctgtcctt ttgcaagatt ttttggcgca tctcttctgc
     8521 caactgtttc atttcctcaa cagataattt tttgacatct gcggggctat tgattgcatc
     8581 caatacatgt aatactgtac tcataataca ttctctcctc cgtactatct tcttttaatg
     8641 aaaatagatt tgttacactt tatctattct actacttaga gttgactcta agtcaatagc
     8701 attttaaaaa aatttcagag aaagcttgtt atataagtag atcttcgcac gaatcaggac
     8761 tcaaataaaa accttctaca gacaattaaa aagctttgta gaaggtctcc taattaaggt
     8821 ctcatcaaga aatatgtttt tttaataggt gaagttcctg agcaatatga tacaaatgga
     8881 tgtttgcacc ttttaatgag attggataga tctttgtctt ttcagtttct aatccatttt
     8941 gatagctagc agcatcgcac aaaaccactc tttttttcgc acatagacat tcatcaggca
     9001 attcttctaa tgaacgaaat aaaataggat ttatttcagc gatgccttct tccgcataca
     9061 aatgaaattg ggttcgataa aaaaattgtt tgactgaact ttctgaaaca acaaaaattt
     9121 ctatttcctg tctccccgct tgttcactgt tgatcaaaga aagacttttg acgaattttc
     9181 gaatgaaatt ttcattccat cttagttgga tttgattttt ctttttccac tcttccaata
     9241 tttctacaat ttttccgtac agaagttgtt ctttttctga tagaagatag atcctttccg
     9301 gtaaaaatac ttgtccatct gcccacaacg tacggacaaa ttgtaaaaag gattgcttga
     9361 aaataaaatt ttctgcatcg tcgatttcag cgatactaat aatctgtaaa atcaattcat
     9421 tcagtgatag gtcattgaga acaaaatttt tataaacaac ttcgaaatct tttcttaaca
     9481 gctccatgtt ctcattggta taatttctac tgttgaacaa agaaaaaata taatagacat
     9541 cttcttcttg taagtctaga attccttttt gctcttccaa tccttgacag actaattgaa
     9601 ataacggctt cgtttctgcg cttttcttat cttcttcttt cagtccaagg ggaaatgcct
     9661 ttcttccgat tgcgatctct attcctcgta tgataaagga cttttcatct tccgaatatc
     9721 ttcttttaaa aaaatgagtc tctacataat caatcaactc gttacaagct tcttctacat
     9781 acggattttt attttcatag ccttcccaat tgacataacg tactaaagct agcaagatgt
     9841 tccgcgagtc aaattctggg ataatgattt ctttattttt caaataatca ttttctttaa
     9901 aaaaatccaa tacgattttt ttgattgtat atactttgct caaagaaata aattcaagat
     9961 cagccagttc tgtactcgtg aatataccat taaaataata acttaaaaac tttaaaaaat
    10021 aagattgacc gtacagaaac tgtgtgagct cagaaagagc aataccatgt ttgaatacga
    10081 gtttatactt atgcttctct cttacttgtt cttttataca atattctaga cactcggcta
    10141 gactttctag atcgtgaagg atcgttggtg tagtcaccct tagagaaata gctgtttgtt
    10201 cgatgtctat ttcttggaat tcaaataatt gttcacacag atacactttt ctaaatatat
    10261 ttcgctcgat gtaattttcc agcattcctg atacacgcct ccagtttttc ttatgatttt
    10321 atttaatcat atctgtaaat cgtatttttg tttccttttt atttagaaaa gccctttcaa
    10381 aaaccaataa aaaaagaaac tgggacaaaa gtcaaacaag ctcacaattt cagcctcatt
    10441 gtaggtagct ttgagccgtt tggactttta ccccagcctc tttcaagaat ggttattcaa
    10501 agatgtcagc gtctagttct ttgactacat ctttcaacaa ttggatacca gctgcgctgt
    10561 taccaaatgg atctagtgcc gggctgaaga cacctatgcc gtaacgattt ggcacagctg
    10621 ccatcaaccc gccgcctaca ccgctttttg caggtacacc aacatggacg gaaaactctc
    10681 ctgattcatc atacaaacca gcagttgtca taattgattt gacgattgta gcactttctt
    10741 cagtaatgat ttgtttgcca ttccaaggag caattccttt atttgccagc acagcagcta
    10801 attttgctat gcctgtagcg gtgacattga gggagcattg tctgaaataa gcatcgagta
    10861 tctccggtac gtctccttcg atcatttgat tacctttcat atagtaagca agagagcgat
    10921 tgatatcacc tgttcttgat tcagaatgat agatttcttc attcaatgtg atattaggat
    10981 catcacagat ctctttcata aatgacaaga ttcgctcaaa tttttcatct gcatctttac
    11041 cggcaatcaa cgaggttgtt gcaatcgctc ctgcattaac aaaaggattc attggatgtt
    11101 tgcgatgatt gatttccata ttcatgatag aattgaaggc aaaaccggtt ggttccgtgt
    11161 tgattgtttg aaagactttt tctattccgt tgtctttgat tgctaataac aatacgggaa
    11221 cttttgacat gctttcgatg gcaaagcgca catcggcgtc tcctccctca atcagttgtt
    11281 ttgtatccaa atcataaatc gccataccta attgtttggg atccacttca gctaatgctg
    11341 gaatgtaatc cgccacttgt cctgtttgat aatagtggaa attttttcca atcaattgtt
    11401 ctaattcttt tacttccatt tgaataacca gctttcattt tttatttttc tgcatgctgg
    11461 aatttatgac ggcatgcgta gatcgtaaat ggaataacta agacgataag ataagaaaca
    11521 atcagaatcg tttcataaat cccatgctgt ccagctgcga tactagcagg tggaacaaat
    11581 gagatacaaa aagcaaaaag tgaagtcaaa agacctaaac aagcaacgat tacttttaca
    11641 acttttccgc ctggaacctg ataggctctt tcaagactgt catctttaaa aaccagcttc
    11701 aaatagcccg cgaaaaacat aaagtacaac atcaggtaga ttacaacagt caatgacatc
    11761 gctgcaagaa atgaaagatt attccccccg ccgcttaatg taaagacggc tgcccagatt
    11821 gttgcaacga tcccatttgc gatcatcaaa tgagcaggaa caccgtgtgt gttttctttt
    11881 gcaaaatatt caggaagtaa tccttcttct gctgctacgt gaagtgcttt tgaaggagag
    11941 gttacccaag aagcaatttc tccgatgaca cctaaacaaa caagaatcgc aagaattttc
    12001 gcaatccatg caagatttgg atcaatgtgt cttaatagga attctaacga ttgaatcacc
    12061 cctgtattaa gagacaaacc atgttgaggt actgtagtag cgacggtcaa tccgccaaaa
    12121 gtatctaaaa tgattgccag aataaccaat acaaacattg ctaatggata atccttttta
    12181 gggttttcca tttcatttgc atgactggca gatgtttcta cgcccatata tgctaaaata
    12241 aaggaaacaa aaacaaccag cgtaggcaat ttcgaaaaat caggaatcaa tgttttcata
    12301 gacagtatcg tttgtagtgg agcgcctgaa gcgacataat ggatccctaa gccaaacaag
    12361 actaatgctg gcaacaagat accagctaca aaaccgatcc gagcaatcaa tgaagtgtat
    12421 ttggttcctt ttaactgtga gagtaaaata gcccagaaaa taatcaatag gattgccaat
    12481 ttcagatatt tattgttttg tatagcacca atacccgttg cataggataa tgcaccagtt
    12541 aagaaataca gcatggtcaa gtagccaact gttatctcaa accattggaa aaagattgcg
    12601 gcaaaaccga atcgttttcc caatgtgcga ctgacccaag tatagacacc gcctttttcc
    12661 catcctttca ccgttgccat ctctgctgcg cacaatgcca cagggataaa ccatagcaaa
    12721 ccgcctaata acaagaaaaa tactaagctg aagcctgagg tcgcgaatgt gggatattca
    12781 tataatgaaa cgaccattga gatggtcata gccaaaaagc caaagaacgt taattttttt
    12841 gcaggaattt tcgttttgct ttgttgcatg aatcttcctc ttttctattt gaatttgttt
    12901 caattgagtt tgttgccaaa gaagaaaaag tccaatcctt cttcttgttc ttcttttgta
    12961 gtagtgatcg ttgtaaagtg catcgccgat tttaaaatca ctgttgtcag cacataggca
    13021 tacacggcag taatgatgac accaatcact tgaatcccta agaagtacca gctgcttgga
    13081 ttcgttagta aatggctgtt agatgcaaag atccctatca gaatcgtacc tgtgaatccg
    13141 cccatgccat gaacacccca cacatcaagt gcatcatccc attgtttctt tttacgaaaa
    13201 tcaacagcag catgacagac gatacccgca atgatcccaa tcagcatggc actttttgct
    13261 tctacataac cggcacaagg cgtaatggct gccaatccag caacggatcc tgttagtacg
    13321 tcgacaaaat caaagccatt tccttttact tttgcaatga tcagccaagt aatcatcgca
    13381 aatgcaagag cgatgaatgt tgaaccaaat gcattgactg cttgttcatc tgctcgaagt
    13441 gcaccaccgg aattaaaacc gaaccagcca aaccaaagca gtcctgtacc gatagcagct
    13501 gccataagac tgctatgctg acttctttct cctaaaggaa tctttctttg accaagtgtg
    13561 aggatacatg ctaaagagcc gaatccagct gtcgtgtgga tgactgctcc accagcgaaa
    13621 tctctaaatc ccatctgatc caaaaatccg ccaccccata tccagtggca aacagggaaa
    13681 taaatcagca gattccaaaa aataacaagt ataatatagc cttttaaatt caatctccct
    13741 gcaaaagctc ctgtcatcaa aggaacggta atcacgataa acatcagttg gtaaagaaag
    13801 aacattaaaa atggaatcgt tgcaccatga aacatgttgg ggaagcttgt aacatgtctc
    13861 atcaaaaaga aatctgccgg gtttccaata acaccgccga tatcccgtcc aaaggccaat
    13921 ccgaatccac caaataccca cataatcgtt gttatcccaa cggagagaaa agattgagac
    13981 atgatcgtta gtatattatt cttccgtgct aatccgccgt aaaaaaaagc tagaccagga
    14041 gtcatcaggc aaaccattgc tgtacataaa atcatgaatg ctgtatctcc tgtattgata
    14101 ggtaatgtat tcattttttt cgcctccttt ctacgattac gagtataaaa gaaggtgtag
    14161 ttgttttttt cttctgtttt tttgaattaa tacttgcatt tataaaagac agacaattaa
    14221 taaaagcttg atgtgttgtg ctctttttcg tttttcacac aaataaagac aaaaaataaa
    14281 cggtcttctt tttatagaaa accgtttatt ttcgtctttt tttattttta aagatatttt
    14341 ttcataagga ataaagaggc ggattttata attaacttag ccatttggaa ataaaaaaac
    14401 gccacgtgaa ttccatgtta tattgaagtt accacaactc tcaatagaca aggatgaatt
    14461 cacatgacgc aaaaccatga taacacagtt tcacgcaagg gaaaacacct aacctactca
    14521 gaacgttgcc aaatcgccat cctgaaaaag gaaaactatt ccaaccgtca ggttgcggat
    14581 gtcctgggct gcgtgccgca gaccataaac aacgaaatca aacgcgggac cgttactcag
    14641 cttaaccgcc agaatcagaa cgggaaggtc tacgactatt atcatgacgt ctacgacgcc
    14701 gatgccgggc aggcggccta cgagaagaac cgcttgaact gcggcagacg gcccttatgg
    14761 gccgacacgg acgccttcat tgaatgggcg gacgacatga tgctgttgga aaaatggtcc
    14821 ccggacgtgg tggtgggctt tgccagaaaa cacgaattgt tcgacccggc cattatccct
    14881 gggaccacca ccctctatca gtggatcgac cgtggcatca tgaaaacgaa gaatatggac
    14941 ctgctagaaa aactgtcccg caaaccgaaa tcgtcccgtc atggcaaccg cccgaataaa
    15001 cgggtgctag ggaaatccat tgaagagcgc ccggaggcgg ttggtacccg gaaaaccttc
    15061 ggccattggg aagtcgacac ggtcgtagga aacaagacca agtcggatgc cgtgctgctg
    15121 acgttggtgg aacggcagac acgcttcgag gtcattctga agctggccgg gaaggatgcc
    15181 gaatcggtca accaagcggt ccgacagctg agagaacggg ctggtgcgta cttcggccag
    15241 ctgttcaaga cggttacctc ggacaacggc tcggagttcg cgggactgca cgatgccttg
    15301 caggatgtgg caaacatcta cttcagccac ccctatgctt cctgggagcg cgggacgagc
    15361 gaaaaccaac acaagctgat tcgccgtttc atccccaagg gcagcccaat cggcaacgtg
    15421 agcgaaaacc aaatcttgcg gattcagcgt tggatgaacg attacccgcg aaagattttg
    15481 ggctatgcaa cgccgcatga cacgttcgtc caggcattta ggcaggaacg gttgacggct
    15541 tgacacgtgg gcccttgaca acgagcctcc ctcggcatgg cttgtgtctg gaaagctggc
    15601 cggggccagc cagtcgggag actaccatgc ctcagctcat tgtcaagggc ccactcgatt
    15661 agaaaaatta gacggttggt ggtaacgagc aaccgggtca ccatgggtgg ctaacttaaa
    15721 cttgaaattt acgtaaggaa taaagaatac ttcatataaa atatataaaa aagaaccgca
    15781 gcgagtgtcg ctacggttct caaatttgtt cttcatttca acataagttt ttcttcaatt
    15841 tgcttataat ttacgtgcaa agaatgaaac gactaatact aaaatgattg caccgatcaa
    15901 tgatggaatg atagccattc ctgcaattgt tggtccccaa gttcctagta aagcttgtcc
    15961 aattgctgaa cctactaaac cagcaatgat gtttgcgatg atccccattg atgatccttt
    16021 attcgtgatt gctcctgcaa ttgctccaat gataccgccg acgattaatg cccaaataaa
    16081 tcccatttta aattcctcct aactgacttc ttacttctta ttgtacacgt ggttcgttat
    16141 tttctttgac tttttgtgca cctttgccta cagcagattt tgctttatct gtttggcgtg
    16201 aagcaaattg tcctgtggat tttgctgctt ctgttacttt gtcttgtact gtttcttgat
    16261 ctttttggta ttcttcttgt gttttgatgt ctgcaacatt cacattcact tcgataacat
    16321 ctaaatgtgt catattgttt acttcagtac tgatcaattc tttgatttgg ttgtaaatat
    16381 cttcgatgtc tttaccgtat tctacgatca catctagatc cacagctact tgtttcttac
    16441 ctacttctgt attgatacct gctgttacgt tatctgtgtt gactaatttt tcagccatat
    16501 ttgagaaaaa tccgccatct aatgtcaata gaccatctac atctttcaat gcataaccga
    16561 tgattttttg gatgactttg tcttcataag tcaattcacc attcatcatg cggttttctc
    16621 ctttttcatt tgccaaaact gatccatttg ttgtattcat gtttttgttt tccatctttg
    16681 tttcctccta tgatttaaaa aattgatcaa ctattcctga ctgtttcaaa taaaaaccga
    16741 ttcctgcgcc aattgctgtc atgattatga tcaacaatgt cttgaaaaat ccaatcgtta
    16801 accataaaac agctagcagt agtccaagac ccccaaagat aatagggagc ttgtatgctg
    16861 aaaatagttc tttcattatt tggccctcct attccactcg agagtgcttg tagtctcttg
    16921 tatcttcttg ttcttcataa ccgctgtatg tgactgccac tttgaccgtt tcttttgttc
    16981 cgagtacttt agttacttct tcttcgatat cttgcatcaa tacacctgtt ttccctacta
    17041 atgaagaagt tcgtttcaag tctccgttga catggatatg gattcgattt ttcgttgaac
    17101 gtatccgtac tttaggtgaa tgaatgaact cttcttcgtg taaatgggaa cgtaccaacc
    17161 cttcgatcgc ttttttgtcg attgttagtt tgccatcttc ccgtttcata acgaaagttc
    17221 ctcttgactt tggatagaaa agaacgacta gcaagatgat aatagcaaga acggcaaata
    17281 ctacagctgc ccagaaaata tattgttgca tgtagtaatt cgttaaagta aagaagcgaa
    17341 atcgttccaa ttgttcaggc ataatatacg gcgcattgat caacgcaatc gctagaaata
    17401 ctgaaagtag cagtaaactc atgataacac cgattatttt taacccctta ttcattttcc
    17461 acctcctata aacttatttt taccctgtaa ataactctac cgacaatcac agtatagata
    17521 gcgaacagtt agcatagcat cagtaaataa agcgctacca aacattgctg gatcataacg
    17581 gcgttttatt gccagtctga tactgaaata acaattgctt acttattctc tatttacttt
    17641 tgattgctgg ctatacttaa aggatattat tcaagattaa aaattgcaaa gattatgctc
    17701 agttattatt acaagattct atttatt
//
LOCUS       DADLIO010000052        17218 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.053, whole genome shotgun sequence.
ACCESSION   DADLIO010000052 DADLIO010000000
VERSION     DADLIO010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17218)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17218)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17218
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.053"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(105..1124)
                     /locus_tag="JOX41_001996"
     CDS             complement(105..1124)
                     /locus_tag="JOX41_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAY6449720.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(1146..2153)
                     /locus_tag="JOX41_001997"
     CDS             complement(1146..2153)
                     /locus_tag="JOX41_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAY6449721.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            complement(2146..2811)
                     /gene="pgmB"
                     /locus_tag="JOX41_001998"
     CDS             complement(2146..2811)
                     /gene="pgmB"
                     /locus_tag="JOX41_001998"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAY6449722.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            complement(2804..5098)
                     /locus_tag="JOX41_001999"
     CDS             complement(2804..5098)
                     /locus_tag="JOX41_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HAY6449723.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            5358..7523
                     /locus_tag="JOX41_002000"
     CDS             5358..7523
                     /locus_tag="JOX41_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAY6449724.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            7827..8660
                     /locus_tag="JOX41_002001"
     CDS             7827..8660
                     /locus_tag="JOX41_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HAY6449725.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(8762..10462)
                     /locus_tag="JOX41_002002"
     CDS             complement(8762..10462)
                     /locus_tag="JOX41_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449726.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            10969..12129
                     /locus_tag="JOX41_002003"
     CDS             10969..12129
                     /locus_tag="JOX41_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAY6449727.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            12145..12588
                     /locus_tag="JOX41_002004"
     CDS             12145..12588
                     /locus_tag="JOX41_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAY6449728.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(13071..13601)
                     /locus_tag="JOX41_002005"
     CDS             complement(13071..13601)
                     /locus_tag="JOX41_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HAY6449729.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            13706..14257
                     /locus_tag="JOX41_002006"
     CDS             13706..14257
                     /locus_tag="JOX41_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAY6449730.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(14410..14883)
                     /locus_tag="JOX41_002007"
     CDS             complement(14410..14883)
                     /locus_tag="JOX41_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAY6449731.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            15021..16493
                     /locus_tag="JOX41_002008"
     CDS             15021..16493
                     /locus_tag="JOX41_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAY6449732.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            16490..17200
                     /locus_tag="JOX41_002009"
     CDS             16490..17200
                     /locus_tag="JOX41_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HAY6449733.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
BASE COUNT         5351 a         3098 c         3536 g         5233 t
ORIGIN      
        1 cacgctcttt tttacagata aacaatgtgt tagaagtagt atcttctttt acataaaaag
       61 ctgaccatag gataaatggt cagcgtattt agtgagtcag ctatttagta tgggttttct
      121 aaaggaacga ctgtctctct tttgatcaag cgatgaggga tgaccaaacg tacgccactg
      181 ctcaattctt catggatcaa ttcgcgcagc ttttgcatag cgacacgtcc taattcggag
      241 atatcgatat cgatacttgt aaggtaaggg tgtgttaatg ttgagaagat cgagttgttg
      301 aagctaatga cggagagtgt ctctggaatg acatagccat acatttgcgc caactgcatc
      361 gtgcgaaggg cgaagatatc gtcaatgacc accaatgctg tggcttcgtt ttctttcaac
      421 gttttctcaa aggacagata atcctccgga tgctctagta ctacactgga taacgcagga
      481 agaccagcca tcatcattgc tttttgataa ccgaaatatc gttcgaaata caaactttca
      541 tgagtcgtgt ttgtcacaaa caggatattc ttatgtccat tctggatcaa aaattctgtt
      601 gcttgtttac ctagaagctg gttatcatta tctacataaa cgatttcgtt ctcatgatga
      661 taaggctgtc cgatcaaagt gaaagggatg tggttttggt ataaataatc aatgacagta
      721 tcttgactat ctgaatacac tagaataaaa ccatctactt gtttttgtaa atgcatacgc
      781 tggacgttct ctaacagcaa ttcaaaattt ttagcagtag cgattgctgt agtcatatca
      841 taattccgcg cttcttcgtt gattgcttcc atgatctcaa gataaaatgg gttaccgatc
      901 cgctcttttg aatcaagagg gggtaagatt acgccgatgg cactggaaat gcgttttcct
      961 agattgcggg cagtcatgtt aggaacataa cctagttcat ccataatttt tcggactttc
     1021 ttctttgttg tctcggaaat actaggatga tcgttgatga cacgagagac ggtcgaggtg
     1081 gcaacaccgg cttttttcgc cacatctttt acggtaatag ccatgataaa aacacctttc
     1141 tcttgttatt gtgcagagaa ccgataaatc gtctgactga tccgttcttg accaggatgg
     1201 aggttgatcg atccaaattt ggggaaatga acgatatcag ggatttcttg cggttcgatt
     1261 gctaatccgt agtttgaatg catctgtttt ccattgacag agaaatcagc ttcgaatcca
     1321 gtcgtagaaa ataataccat acttttatta gaagttgcta tagtcatttg gcgaccagaa
     1381 tgcttctcga ataattgtaa ggaagttttg gaaagcctag gatgatgcaa aagaaataca
     1441 tcatctagtc catctggata acatgcaagg atctcttgca gtgttgggga ttttctaaag
     1501 tcgattggca gtttttcttt ttttgtccaa tttccagtag gcagtttttc ttgatctaat
     1561 tcaagcacac catctaaaaa gaccgttaac tgatgttcat agatgtctct tgttccattt
     1621 cctgaaaggt tgaagtaggc atggttggtc ggattgcaga tggtttcaac aaggctacta
     1681 gcagaggttg tcatctctaa ttcgtttttt gttaaacggt aagtgatcgt agcagtgatt
     1741 ggtcctggat aggtagaaaa ttcatctttt aagtaaaaga ccacacctat tgatgatgga
     1801 gttttgaaaa cttctacttc ccaaaattgg aaagaccagc ctttcgtgcc accgtggata
     1861 tggtgtgatc cgcagttttt ctccaatcta tgctcacccc aagaagcatc ccggatcctt
     1921 ccggctacag gtccgacagt tgctccaaaa aagcttttgt ctgttagaac atcttcgaaa
     1981 cgatcgtaag acaataaaac attttctgat tttccttctt tgtctggtgc gaagatttgg
     2041 tgcaggcggg caccgtaatt gagaagaacg acttctaagt agtcgttctt caatgtgatt
     2101 ttctttattt cagtctctgg aactggtacg acggagatct ctggattatc catggtcatg
     2161 ccacttttct ttcaagtaat cgatcgtaag aaaagtcgta tcagggacaa gcgggatctc
     2221 ctctccaagg tcttcagcac gtcccacgcc aattggttga gcgccacttg agaggatggc
     2281 ttggataccg gcttgcgcgt cttcgatccc gatacattct tctgctttta gtccgacagc
     2341 ttttgctgca aggaggaaga tatctggcgc aggttttccg tttgttgctt ctgccgggtc
     2401 ggcaatagca tcaaagtaag gtgtaagacc cattttttca agtaggaatg gcccgttttt
     2461 acttgcagaa gcaagagcaa tcttgatttt ttcttctttt aaagaatcca gtaaaggcac
     2521 gaccccgggg aagacatctt ttggttcgat cgtctggatc atctctaaat aataatcgtt
     2581 ttttcttttc gctaattctg caaattcttc ctttgaaaaa gagtgttctt ttccgccata
     2641 agctaaaagc aaagagagtg agtcttctcg gctgacgcct tttagctgtt cgttgaatgt
     2701 gtggtcgatc gtaatgccga tttcctgacc aagctttcgc caagcacgat aatggaattc
     2761 agcagtatcg gtaatgacac cgtctaaatc aaacaatacc cctttaaaca tttgcttcct
     2821 cctttcttag cgttatttct agacgatccg ctaaagaata agactgttca tagacgtaaa
     2881 tttctagagg agaaccttct aataactcga aagtaacttg ttcatctgtg actgagatga
     2941 acaataaacg tccgcgataa ttgatatgga aagaataagc tttccaagtt tttggcagaa
     3001 atggtgcgaa tctcaactga tcatgggcag ttttcatttg agcaaatcct tggacaatcg
     3061 acaaccagct accagtcatg gaagtgatgt gcaagccgtc ttctgtgtcg ttattgtaat
     3121 tatccaaatc caagcgagct gttcgctggt acatttctac agctttgctt tccattccta
     3181 attctgctgc taaaatcgaa tggatacttg gcgaaaggga agactcatgg acagtcattg
     3241 gttcatagaa atcaaagttt ttttgctttt cttcttttgt aaaagtatca ttgaagaaat
     3301 aaatcccctg tagtacatct gcctgcttga tgaagcaaga tctaaggatt ttgtcccaag
     3361 accaatgctg attcagagga agatcgcttg tgggaatatc ggatacaggc atgagatctt
     3421 tatctaagaa tgtgtcatgc tggacaaaga ttcctaattc ttcgtcaact gggaagtaca
     3481 tgttctctgc gatatctttc catttggcta gttcttcttc gctgatagtg atagcagctt
     3541 ctttttgata agttaaataa ttttctcgcg tgtaacgcaa gacccaagct gcgatcgtat
     3601 ttgtatacca attgttattg atattgttct catattcgtt tgggccggtc acaccgtgga
     3661 tcatgtattt atttgctcgt tttgaaaaat ggacacggtc tgcccagaag cgtgcgattt
     3721 ctgctaaaac ttccagtcct tcatttttca aatattccgt atcgccggtg taattcgtat
     3781 aattgtagat tgcataggca atcgcgccat ttcggtgaat ctcctcgaat gtgatttccc
     3841 actcgttatg gcattcgaca ccagtgaagg tgaccatagg ataaagcgcg ccttttaatc
     3901 cttgttgctg agcgttgtgg attgcttgcg gcagttgatt atgccgatat ttcagcagat
     3961 tcttagttac ttcaggtttg gctaaagcaa gataaagagg gacagcatac gcttctgtat
     4021 cccagtaagt ggctccgccg tatttttctc ctgtgaatcc tttggggccg atattcaatc
     4081 gttcatcttc gccgtagtaa gtagagaata gttggaacaa attgaatcga ataccttgtt
     4141 gtgcttcttc gtctccttcg atgaccacat cggcaagctt ccatcgttct gcccaagccg
     4201 ctgtttgctc ttcttttgct tggatataat tgtttgtctg gttcgttaat tctgagacag
     4261 ctttttctgc ttgctgcgct tctggaatat ctctactagt aagaacgata atttcttttt
     4321 ccactgacca tgtctcacct tgagataatt ctgcagacaa gcaaccatgt aatgctaaag
     4381 tatcttcgtg atagtcaggg atgactgatt ttccattaac gaaatggcgc attgctgcag
     4441 taacagtaaa ttgttcaatc ccaaagttgt ttggaatagt tttagtcgtc aaatagccga
     4501 tttcttctat agttccacga tcaatctcat tccaaaaatg ttcatcatag ttgctgtctt
     4561 cgttttgaac atttccatcc aattttgata cgagtttgac tgttccgcta ccttcaagca
     4621 tttctatagt taaatagata taagctgatt cttttttgac aatgctcaga aaacgttcga
     4681 aggaaatgcg tactttatta gtagaagtag tgattgtgaa tgtacgagat aatacaccat
     4741 ttttcatatc taattcccag taaaagtctt ctggttccaa agaagccaag tcgatcagct
     4801 gatcgttgat cgaaatatct atcgcgataa agttcaaggc gttgatcact tttccaaagt
     4861 attctggata accatttttc caccagccga cacgtgtctt atcgggatac cagacacccg
     4921 ccaaataagt accttgatgg tggtcccctg agtaagtttc ttcaaagttc ccgcgcatcc
     4981 ccatataacc gtttccaata cttgttaaag attcttgcag tcgaagattt tttttatcta
     5041 attgtgtcgt gctgattttc catggatcaa tagcaaatag tcgtttgatc tgtttcattt
     5101 ttctcctcct aatgagctgt tttatacgtt cataataaac gcaaccgatt gcacaagtca
     5161 atagacaaaa gaaaatattt catagaaaaa agcttaaaaa aataaatttt taggagaaaa
     5221 ttatagaagg gaacacacgt attataggtt ttatagaatg gtatagacag aaaaataaaa
     5281 aataaagcat ttacaaaaaa gaaaacgcac gctataatac gtttaacgaa accgattgcg
     5341 taaaggagct aaacggaatg aaaaagatat ttagttttga gttttggcaa aaatttggaa
     5401 aggctttaat ggttgtggta gcagttatgc cggcagctgg gttgatgatc agtataggga
     5461 aatcaattcc cttgatcaat cctgattgga cgccgcttgt cacaacgggc ggagtaattg
     5521 aaaatattgg ttgggcaatt attggtaatc ttcatatttt atttgcttta gcaataggag
     5581 gaagttgggc aaaagaaaga gcaggcggag catttgcagc tgggatctca tttattttaa
     5641 tcaatcggat cactggggct atctttggtg tcacaagtga catgcttgcg aatgaagatg
     5701 catttaccca cactctgttc ggtacgaaga tcatggttaa aggatttttt acaagtgtat
     5761 tggaagcacc agctttgaat atgggagtat tcgtagggat catcgctgga tttgtcgggg
     5821 caatggctta taataagtac tataattata gaaaattgcc ggatgctttg tcatttttca
     5881 atggaaagcg ctttgttccg tttgttgtta tcttatggtc aacaatcgtg gcattgattc
     5941 ttgctgtggt gtggccaaac gtacaggctg gaatcaataa ttttggttta tggattgcag
     6001 aatcacaaga aagcgcaccg attctagcac cgtttttatt tggaacatta gaacgtttac
     6061 tattgccatt tggattgcat catatgctga cgattcctat caactataca cagcttggcg
     6121 gatcgtatga gattttatca ggcgcacagg cggggacaca agtatttggg caagatccgt
     6181 tatggttggc ttgggccact gatttagtga atcttaaagg tgcaggggat atgtcgcaat
     6241 atgagtttgt gttgcataac tggacgccgg ctcgtttcaa agtaggacaa atgattggtt
     6301 cttcaggtat cttgatggga atggcttttg cgatgtatcg taatgtcgat cctgataaga
     6361 aagcaagata taaatcaatg tatttttcag cagcgttggc tgtctttcta acaggtgtaa
     6421 cagaaccatt ggagttcatg tttatgtttg ctgctgtgcc attatatgtc atttattcag
     6481 tgatccaagg ggctgcattt gcgatggcag atatcttgcc attgcgggtc cattcatttg
     6541 ggaatatcga attgctgact cggacaccgt tagctatcaa agcgggtcta ggtggagatc
     6601 ttatcaactt cgtgttgtgt gtgatcgctt ttggtgttgt tacgtatttc ttagcaaatt
     6661 tcttgatcaa aaaattcaac tttgctacac cgggacgtaa cggaaattac gacaatgaca
     6721 gtgaagaaac cgttgtatct aacagcggaa caggaacagc agatcagcaa gtggtccaga
     6781 tcattcattt gctgggagga aaagaaaata tcaaagatgt cgatgcttgt atgactcggt
     6841 tacgcgtaag tgtaaatgat cgagaaaaag tagggactga agaagcctgg aaacgagcag
     6901 gggcgatggg attgatcgtc aaagacaatg gagtccaagc agtttatgga ccaaaagcag
     6961 atgtcttgaa atcagatatc gaagatctgc tgcaatcagg agcagagatt ccagagccag
     7021 aaatggtttc tacaggaaat ggacaagcag gtagtaagca atacttaggt atagaacaag
     7081 aactagtttc cgcagcttct ggagaagtga ttcctttatc tgaagtaaaa gatccggtat
     7141 tctcacaaaa aatgatgggt gacggctttg ctgttattcc aacatcaaga gaagttgttg
     7201 cgccgatcgc tggaaaagtg acaagtattt tccctagcaa acatgcaatt gggctggaaa
     7261 cgaaagatgg tatcgaagtt ttgatccata tgggaatcga tacagtccaa atgaatcagc
     7321 cagcttttga gattgctgtc aaagaaggcc aagaagtagg aacaggaacg aaattagctg
     7381 agatggatct tgatgtgatc caaaacgaag aaaaagatcc aacgatcatg atcgtattta
     7441 caaacgataa agtagaagaa gtagtgatca agcaattagg tacagtgaca gctggtaaag
     7501 tgatcggctc cattaaaatg taaggagagg ttgtgaaaaa gctgtcctgc atcaagtcat
     7561 aagaacagcc aaacaaaaat agctcctcct atttttcgtt tggttgggct tattaccgag
     7621 aagcagcagt ttgaatactg tttagtggag aggtcgtgaa aaagctgccc tgcaccaagt
     7681 gataaaaaca gccaaacaaa aaatagctcc tggtccattg agcttattac tgaggagtta
     7741 gcaggagaac actatttgct ggagaggttg tgacaaaaat tttgtcacaa cccttttgtt
     7801 tcgaaatgaa gacaaggaga aaaccaatga aattcatgac actcaacacg catagctggc
     7861 ttgagccaga accagagaaa aaattgcaag aattagcaga taagatcctg ttagaagatt
     7921 atgaagtgat tgctttacaa gaaatcaacc aattactgga atctgaagaa gtagaacctg
     7981 cgaagctaat gaagttctgt ccggtaaaga atcaagtacc tatccgtaaa gataattttg
     8041 cctaccgttt agttcagctt ttaaaggaac acggaaaaga gtatttttgg agttgggaaa
     8101 tgagccacat cggttatgat aaatatgaag aaggaaatgc actgcttacg aaaaaaacat
     8161 tggaaagtca ggtccttacc gtctcccaat ttcaaaagaa agaagattat cagacacgca
     8221 agatcttgat tgggaaaaca aagatagatg atcaggacat ttttgtctcg agctgccact
     8281 tttcttggtg gacagataaa aaaagtggct tttattttga gtggaaaaac ttggaaaact
     8341 actttttgga aactcgcgta ccactttttt tcctaggtga tttcaataat ccagtagact
     8401 ctcaaggtta ttatactgta agagaaagtt gccttcttct tcaagattcg tatgttgtcg
     8461 cgaatgaaaa aggaaaagca gctactgtgg aaaagaaaat agatggttgg gaacaaaata
     8521 cagaaaaatt gcgtatagat tttattttcg tccctgaagg aatgcaggtt aaaaaatatc
     8581 aacggatttt tgatgggatc gatagtccaa tcatcagtga tcactacggg gtggaaatcg
     8641 aattagatgt gaacgaataa aaaatataac atataacata aaaaaactga ttaaaataaa
     8701 actctccaaa cgattatacc gtttggagag ttttttgatc ggatgtattt atcccttttg
     8761 cctaagcacg taaaagcttg tatctatgat aaataaataa acatagcaag gtaaaccagc
     8821 caatcaaagt aagagaaaga atgaaataga aatagattgg cgtttgataa tgaagcgtga
     8881 gctcgttgat tcctttttgc tgcttcacga ttggggtccc gatatctgtt acttcataat
     8941 cagtcaatgt ttttccattt tgctgtagca cagtccgatc gtagacgata acagggatat
     9001 gaacagtttt gtccccagtg tttttccact tgattgtcaa aagaccgcct ggatgtgttt
     9061 ttataaaagt tgtttcgttt tctagtattt cttcgttata ccggtcgtat ttattgtctt
     9121 ttgtctcctt atagattggc agatagtcag gtgtggtttt ttggaaaacg aacaagctgg
     9181 tagacatatc tttgctgaag aatgttttcc ttgcttcttc cggcgtatcg aatagataag
     9241 tatgtcgact gacaaatgtt tcattttccc acttttccag atgctggtat aagttctgga
     9301 tcgtctgtgc tgaaaaaata agaatgccaa atatacttaa aagacggaac cacttttgtt
     9361 cagaccactg gttcagtgaa agggcaaggt aaagtagaag caatagcgta aatggcacga
     9421 aaaatcgaaa tggaaactgg atcaaactaa taaaaggcac atttttttcg atcaatgtcg
     9481 tccatggaat caagctagta gaaagaaaaa agaaaacaag acttgtgtac aacacgattt
     9541 tttggaataa ggtgttcttt tgttgaaaga aaataaaaag caaaaaacct gataatatca
     9601 atataggaaa ggccttaggg taatggagcc aataactgcc atccagatct atcgcctttt
     9661 gactcatttc tctgttaaca aagggaggaa gaatcttatt cccactgtaa acaatagcta
     9721 atcctgccca aatatttgct gtcagaacaa aataaagcaa gaccgactta atcagttgaa
     9781 gcagtgcttt tcctttttca gtctggttaa aaaagtaata aagataaaaa gggatataca
     9841 tcaaagctaa catgatcgaa gacagtaaat ggatctgtgt cataagtccc actgagacag
     9901 cgactttgat aacagggaac tttttatgaa ggacgaaatc agcaataggg atcatacata
     9961 aaggataaaa acaagtcccc cagctagtga atccttggtt gatagaccag tattgaatag
    10021 aatacgtact catgaataaa acggctactg gtacacttac ccaatttcga acattgacat
    10081 atctcagtaa aatcagcata gaaaatcctg aaataagata aagaatgaaa tttgaaagaa
    10141 tctgataatg aaaccagcta cctgcaagca acacgatcaa tccttgtaaa taagcgaaaa
    10201 atgggccgta aacggcattc acgatcctgc cactttgctg gaatccataa agggaaggaa
    10261 aataatggaa atccccatat ttaatttgtt gcgcggcatc atagaaccga ttgtaatgga
    10321 atggggcatc agcacccaaa attagtttat gtgtgaataa atgaggcatg agaaatgcca
    10381 aagcaatgaa aaaaattgct aaaaatgggc catatttttt caattgtcga actcctttgc
    10441 aaactttaga taaattcatc atatatccta tgcgagaggt aggcaagaaa ttagaaaatt
    10501 catgaaaata tttatgaatt ttacaagaaa aacataagtg aaagttctaa ggagagagga
    10561 tgcgacataa gttttgttgc atctccttgt tttgaaacag aatttttctt aatactcgaa
    10621 acaaagtagc tttttcatga cctctcggta aacggtgttc aatcagctgc ttctcggtaa
    10681 taagctcact agcctagaaa atatgagaag ctattttctg actagcgctc ttattactca
    10741 aagcataacg cagttttcac aacctcttcc ttaaacggtg ttcaaaagct tgcatctgcg
    10801 gtaataagcc caacccaaca aaaaatatga gtagctattt ttttgggctg tacttattac
    10861 ttgatgcagg acagcttttt cacaacctca tcggctttca ttttctattt ttttcctgaa
    10921 cccatataat aaaagaaaga acaaaaaaac ttgcaaggga ggacacatgt gaagcagagt
    10981 aagcaaaaac agtctcgtcg acttttgttt cgtttgtttt tattaatatg tatcgtcgta
    11041 gggttactga tcgctttata tccattttat gtggattctt taaatagttt tattgatcaa
    11101 aaacgtatcg aacaagtaca aaaacggacc gcagctgaaa ttgaagtgca gcgaaagaaa
    11161 atggaggaga aaaaccaacg attaactgac caaggattca atcctggtac tgatcctttc
    11221 aatgaaaaga acagaaatga aagtacaaca tccagccaat tagaggaatg gctgatcgga
    11281 agtatcaata tacctaagat ccaattaaat atttcacttt atgatcggct caatggtagg
    11341 atccttgaaa atggagcagg cgtcttgcaa ggaacctctt tcccgcttgg tggaaattcg
    11401 acgcattcag tgatctctgc tcacagcggt ttacctaatc gacggttatt taccgaatta
    11461 gatcgtttag aaaacggaga cacgtttatt ttgactgttt tgggggagaa attggcttat
    11521 caagttaaaa atatacaagt ggtactgcca gatgacacgt ctgttctaac gatttcagaa
    11581 ggagaagact tagttacctt gcttacatgt acgccgtata tgatcaacac gcatcgtttg
    11641 ctagtgacag gacatcggat tccttataac gaatcggtaa aaaaagaaga aggaaaagga
    11701 aatcaggaaa gaaccatgcg gcaatggttt attcttgcag gaacgataat agctgtagtc
    11761 atactgttag tgtttatcgg acgactaatc tatcagtata gattaagtaa aaaagtgctt
    11821 gatttttcat ttattattag tgattcgtca gggaaaccgg taaatggtag ttcattcatt
    11881 ttgaaacata agaaaaaaac acttactaga aatggtgtgc cgttttcagt acaaagcgac
    11941 catcatggga aagtcaagct ggatcaattg cctggtggaa cttatcgaat cgtttcagct
    12001 gatgatccta aagttgctgt ttcttttggt attagaaaag taaaacaaga gaagatatac
    12061 ttttttgagg ggcgaaaact tgtaaaagag cttcaaaaaa atggttttta ttttaaaatc
    12121 aatgaataag taaggagaga aaaaatgatc cgcacaacaa caaaattgtc tgccaaagaa
    12181 ctggaatctg ttctatcgat ttggctgcat gctaacttgg attctcatga attcattcca
    12241 tcaacttatt gggagaatca agtagaatct gttaggaaag ctttaccaga tgcagtgatt
    12301 tacttagcag aaatagatca agaaattatt ggttttgctg gggtgattga tcagtttatc
    12361 gcaggaatct ttgtgaaaag ggaataccgg caacaaagaa tcggtacgca actaatgaaa
    12421 aaaataaaag aaaccaataa aacactgact ttgacagtct atcaaaaaaa tcaatcagct
    12481 attcatttct atctttcaca aggttttaca attcaaacac agcaaaaaga tgaagcagta
    12541 aatgaggagg aacttgtgat gaaatggaat caaaacgctg atttttgatg aacagaataa
    12601 cgaaataatg ctcccagcct aattttttgc tgggagcatt atttcatttt gaagtcacta
    12661 atttaactgt gtgaatatgc agttgttaca atctttgata aacggtgttc aatcagctga
    12721 ccctcggtat tagctcaaaa aacggcaaaa tatgaggaac tatttttcca tttgtttctc
    12781 taatactcag gtcaaaacgc tgatttcaca acctcttgat aaacggtgtt caaacggctg
    12841 cttctcggta ataagcccac tagcctagaa aatatgaaaa gctattttct aactagcgtt
    12901 cttattactc aaagcataac gctgatttca caacctcttg ataaacggtg ttcaatcagc
    12961 tgaccctcgg tattagctca aaaaacggca aaacatgagg aactattttt ccgtttcttt
    13021 ctctaatact caggtcagaa cgctgatttc acaacctctc tttcacaacc ttattttact
    13081 cgtttataat tttcatcgaa gtattttccg ctacggatat catctggcat tccatcgtat
    13141 ggttcttcgc taataacatc ttcattgtct atacctgcat cacccatata agtgatcgta
    13201 gcaaattcag gaacaagtaa ttttggataa gtttcatatt tttcacgagc tgcttccatt
    13261 tctgcgatat gttcgttttg gaaagtaaca gtgatttctg gatgttcttc aacccattta
    13321 gggaaaaaga tcattccgtg aagtttcttt tcatttggca taaagtccaa tgccacgtct
    13381 gtccctgttg gctctgtcca agtgattttg aatacgccgt ccgtcaattt aacgatatca
    13441 gcttcttggt cttttaccca acggcctttg accattccgc catggatacg gtaatcaaca
    13501 gtatggtcat ttttggcata ccattcatat tcccaaccat tgtcatacgt atagataaag
    13561 tgagttccaa taaaatcttc caattcttta aattctttca tgtttaagca tctccttata
    13621 aattaaaaca tgtaataaac tacatgtttt cgattactca tttatgatag aatggattta
    13681 aagatttgtc aaggagggaa aactgatggc aagaaaaaat acacttcgat atattttgtt
    13741 agggttatta agtaagaaga agatgacagg atatgaattg aatcaatcgt tcaaaaatga
    13801 aataggagaa ttttggcaag caaaacatag tcagatttat cctgaacttg caaaaatgga
    13861 agagcaagga atcattcagc atcaagtaga gatcacaggt gaaaaattgg aaaagaaagt
    13921 ttatgaatta acagaagaag ggaaggaaca attggcagag tggattcata cacccaccaa
    13981 tgaactaccg gttaatcgag acgaatttgt tctgaaattg tatttcgtca aagacgtgaa
    14041 tgatccggca ttagtagaaa ttattcagca gcagcgtgac cttcatgaag aaaaacgact
    14101 tcatctatta gagcgaaaaa aaacgatctt tcctactgaa aaagaaaaac atgaaaatta
    14161 cggacactac ctgattttag cgcatgcgat caatcgggaa acagaatatg caaattggct
    14221 aacagatgta ttagaagaaa gtaaccgaaa aaaataaaaa aatatccgaa cagtgatgga
    14281 gaattccttt ctatatgaaa gaaacgcaga tcaccgttcg gatattctta tgttcaaaca
    14341 ggcctttttt caagtattta tgtagcatct acttattaaa aagcttggta cttaggagat
    14401 tagtggcgtt tagagttctt ttaacaactg ttcgtagtca gctttttcat cgacaggaag
    14461 gagcttgtaa gttaattcgt ctgtctcgtt gtcatgaatg atgtacatct tagcattctc
    14521 ttctttgaag ttaccgattt gtaaaatcgt atagcgttcg tcgatcaatt cgatatcttt
    14581 gattgctttt gaaaaaactt tacggacatg gtgcattttc ttttggcgga tttctgcctt
    14641 ttctgcagct tttgacaaag taaatccgtc atctaaatat tttttgatca gttctacttt
    14701 tatgactgta ggtaaacgat attttctagg acaattcgca tcagcttcga tcgaacgaat
    14761 gaatcccttt tgttcccaat accttaattg acgtggagac acacctacga tatcacttaa
    14821 ttcactgatg ccaacaacca attgatcatt ttccaacaaa cgtttaaggg aagccccaac
    14881 catttttgtc actccttttg tcctcttgct tcccttaatt atatccgtat taacttatgt
    14941 gtcaagtagg ttgacaaata gcgaatttag gactaaagta ttctagtagt ttcagaaaaa
    15001 attcagaaag aaggagaaat atgagtaaca accaacccgt agatatttac ggaaaaccat
    15061 ataatcggac acttttagtt gttgtcttat taattggtac attttgtacc gttttgaatc
    15121 agaccttatt gacgacagct tttcctacat tgatgaaagc tttcgatatt tcagcgtctg
    15181 atgtgcaatg gttaacgact ggtttcttgc tagtcaacgg gatcatgatc ccaataacag
    15241 catggctgat caataaattc agttcaagaa atttatatct ttctgccatg acgatctttt
    15301 tgatcggaac gattacttgc tttacagcac ctaattttag tacattacta atcggtcgtt
    15361 tgatccaagc ttgcggtgtg ggagtatcga tgccattatt gcaaaatatc atgctatcta
    15421 ttttcccgcc agaaaaaaga ggatcagcaa tggggatgtc agggatcgtt attggacttg
    15481 ctcctgcttt aggccctaca ttatctggtt atatcattga taactaccat tggcgtgact
    15541 tgtttggtat ggtactgcca atcgttgttc ttgtcttggt tttagcattc ttcctaatga
    15601 aaagtgttat tccattgtca aatcctagca ttgatatttt atccgctatt ttatcaacga
    15661 ttggattcgg tagtttactt tacggatttt ctagtgtagg agatgacggc tggggaagct
    15721 tgaaagtaat tggtttctta gttgttggtg tgattttcat cgccttgttc tcatggcgtc
    15781 aattacattt ggaacatcca ttcttggaac ttcgtgtatt caaatcatct acattcacga
    15841 ttgcagctgt tttagctggt gtaacaaata tggcgatggt aggggcagaa atggtcgtac
    15901 cattgtatat tcaaaatatt cgtggagaat cagcattcca ttctggcttg atgttgttgc
    15961 cgggtgcatt gatcatgggg gctatgatgc ctgtgacggg tgcgattttc gataaatacg
    16021 gcgcgaaacg tttagccatc acagggatgt tcattttgac agcggcaact gcaccatttg
    16081 ctttcttgac aaaaacgact ccagttttat atatcgtgat cctttatgcg atccgtatgt
    16141 ttgggatctc catggtcatg atgccggtaa cgacttctgg tatgaatgca ttgccaaata
    16201 acttgatcag tcatgggaca gcggtaaata atacattccg tcaaatcgca agctcgattg
    16261 gtacagctat tttgatcagt gtgttgacga atgtgacaaa agcaaatatc ccaagcaaat
    16321 ctgtattgga taatacgcca ttagcttata aagatcaggc aatcaatgcc acactgtcag
    16381 gttaccatgc cgcgtttatc gtagcgatca tctttgggat tcttggcttt attattgcct
    16441 ttttattgaa gaaaaaagaa cctgttctaa tgaaagcggg ggataatgca tgattattgg
    16501 agttttgatt gtcagcttgc ttgcttttgc tttaacgaac gtgttcgcta aaaaaacatg
    16561 gcaaaccttt ttatctttga ttttcggact aatcttcgtc gcttcactaa gtttgatcgt
    16621 cgctaatttg tccaatcact ttggaatgga aaaagtaacg gaaacaaaaa cagaaaaaat
    16681 tgtttccagt gctgattccc aaggagcaga tatgcttttg tataaagctt tagggaatgg
    16741 aaaagaaaaa gtgtatcttt accgaacaaa tgaaaaacaa gaaaaaccaa aagcaactgg
    16801 tacggataac gaaacaaata aagtagaaaa gacagacggc gatgctgaaa aagtgacgaa
    16861 aactacttat tgggaataca aaaacgacat gtataaattc tggttcaata ttgctgataa
    16921 caatcacgaa tatgacagcc gagtgaatac attcaaaatc ccagagacat gggtagaatt
    16981 aagtacggac caagcagcca agttagctga attagtgaag aaacagcaaa gtacgatgga
    17041 aagtgaagca aaagcttatg ttcaagacgg tatggtaaaa gcaatgactg aaaatccaaa
    17101 aatgagcaaa gcagagcaag aacaacgtac gaaagcctta gctgctgaat tccaacaaca
    17161 agcattcgca aaattagtga aagaagcaaa aggcgaataa tattttgaac accatgta
//
LOCUS       DADLIO010000053        16494 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.054, whole genome shotgun sequence.
ACCESSION   DADLIO010000053 DADLIO010000000
VERSION     DADLIO010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.054"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            <1..525
                     /gene="scm"
                     /locus_tag="JOX41_002010"
     CDS             <1..525
                     /gene="scm"
                     /locus_tag="JOX41_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HAY6449734.1"
                     /translation="TSASSDSTDTTSTTSDSTDTSASSDSTDTSTTTSDSTDTSASSD
                     STDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSD
                     TRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVI
                     GLRITFMSYKKSKR"
     gene            complement(680..1666)
                     /locus_tag="JOX41_002011"
     CDS             complement(680..1666)
                     /locus_tag="JOX41_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HAY6449735.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYEGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(1689..2255)
                     /locus_tag="JOX41_002012"
     CDS             complement(1689..2255)
                     /locus_tag="JOX41_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HAY6449736.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKRDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(2269..2685)
                     /locus_tag="JOX41_002013"
     CDS             complement(2269..2685)
                     /locus_tag="JOX41_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HAY6449737.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(3142..5076)
                     /locus_tag="JOX41_002014"
     CDS             complement(3142..5076)
                     /locus_tag="JOX41_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAY6449738.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5378..6313
                     /locus_tag="JOX41_002015"
     CDS             5378..6313
                     /locus_tag="JOX41_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HAY6449739.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            6403..7506
                     /locus_tag="JOX41_002016"
     CDS             6403..7506
                     /locus_tag="JOX41_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HAY6449740.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            7519..8472
                     /gene="menA"
                     /locus_tag="JOX41_002017"
     CDS             7519..8472
                     /gene="menA"
                     /locus_tag="JOX41_002017"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HAY6449741.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(9286..10632)
                     /gene="gor"
                     /locus_tag="JOX41_002018"
     CDS             complement(9286..10632)
                     /gene="gor"
                     /locus_tag="JOX41_002018"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HAY6449742.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(10766..12007)
                     /locus_tag="JOX41_002019"
     CDS             complement(10766..12007)
                     /locus_tag="JOX41_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAY6449743.1"
                     /translation="MTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAYGLRS
                     RAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISAVIVS
                     DPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVAEIRK
                     NTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFGQERN
                     SLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNVYKAA
                     VDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVYKFVG
                     EVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRAPNPM
                     MILTMPVAQPVKPGDMIRKRK"
     gene            complement(12025..12948)
                     /locus_tag="JOX41_002020"
     CDS             complement(12025..12948)
                     /locus_tag="JOX41_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAY6449744.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(13169..15661)
                     /locus_tag="JOX41_002021"
     CDS             complement(13169..15661)
                     /locus_tag="JOX41_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HAY6449745.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(15668..16135)
                     /locus_tag="JOX41_002022"
     CDS             complement(15668..16135)
                     /locus_tag="JOX41_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HAY6449746.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(16271..16344)
                     /locus_tag="JOX41_002023"
     tRNA            complement(16271..16344)
                     /locus_tag="JOX41_002023"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16308..16310),aa:Arg,seq:acg)
     gene            complement(16402..16475)
                     /locus_tag="JOX41_002024"
     tRNA            complement(16402..16475)
                     /locus_tag="JOX41_002024"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16439..16441),aa:Pro,seq:tgg)
BASE COUNT         4868 a         3460 c         2932 g         5234 t
ORIGIN      
        1 acatcagctt caagtgacag tacagatact acctctacca caagtgatag cacggacacg
       61 tcagcttcaa gcgacagtac ggatacatct accacaacaa gtgatagcac ggacacgtca
      121 gcttcaagtg acagtacaga tactacctct accacaagtg atagctcaga ttcatctacc
      181 actacaagtg atagcacgga cacgtcagct tcaagtgaca gtacagatac atcctctacc
      241 acaagtgata gctcagattc atcaacttca agcgatagta cagacacgtc gtctaccaca
      301 agcgatacac gtcatgcaag tgtctccttc tcaaaaacaa gttcggataa caggacgaac
      361 tttaacttaa ctaataaaac aagcaatgac aatggaaaca aatcaaaaag agcacttcct
      421 aaaactggaa gtcaatcgaa taattggata acactcgcag gcgttatatt acttgtaatc
      481 ggtttaagaa tcacttttat gagttataag aaatcgaaaa ggtaaaaaaa tattcaagat
      541 aaaaaagagc aacgtcgcta acggacgttg ctctttattt ttgcttttta tcataaatac
      601 aagaactaca attcaatttg tcaaaaaaca cgtagatttc cttctgagaa atttatttac
      661 gtatcgaacc tttccctatt cagtctttgc gatccaaaat cagttgggta agggaaaaga
      721 gattctcttt tgttcgaaga gaggtggcag gtaatttctt tatttccttc aaagcctttt
      781 ctgtgtaaga ggccgctaac ttcctagctt cttccacgcc tcctgtatgt tcaacgattt
      841 tgcgtacggc gtcgacatct tcttctgtca ttgccgcttt cttctctaaa taaggtagta
      901 gctttggttt gtttttttgc aaagagtaga tcaacggtaa agaatagacc ccttgacgca
      961 tgtcttctag tacaggtttg ccgatttcct ggctctcttt tgtataatct aaaatatcat
     1021 cgataatctg aaaggccatc ccgatagaaa gtccgatatc tcctgctttt tttgcgaagc
     1081 gctcgcttgt tccactttca aaagcgccaa cagaacaact taattggaac agttcagctg
     1141 tcttacctga aatattttcc aaatattctt ttacagaaag ttcataatta tagcgatcat
     1201 ccatctgccc taattcgcca ttcaatactt tttccatact gcgagaattc aattggagac
     1261 ttttcaagga agtggagtaa tcagacaata gtttaaaaca gcagacaaat aaatagtctc
     1321 cttcatagac agaaacgaca ttaccaaact gactacggat attaggctga ccacgtcgca
     1381 gatccgcttc atcaacgata tcatcatgga tcagtgtggc cgtatggagc atttcgatag
     1441 aagctgccaa agcgatggct ttgtctcgat cttgctctgg tccaaattgt gagaacaata
     1501 gctgataggc aggacgcaac agctttccgc cggcatggat cgtttctttg attgcttgtt
     1561 cgacaggttt gtttttcagg cggacagttt cttccatccg ttttagtgtt tctgtcaatt
     1621 ctttacttaa agcaggatag ttttcccaca ttggatgtag cttcataaaa aaactccttg
     1681 tgtgacgatt attttttggt aaacattggg ctccattttt gtttggttcc ctgctcataa
     1741 tctttttgga atcgttgaag tgtctgcaca tgtcgtaaaa gataattcgc tgcgatcccg
     1801 attgcaatcc ctgataaaat ccctaaaact gaaaggactg gcaagtacaa catgactgtc
     1861 catgattgtg caatgaaaga agccatcaaa agctgtccga cattatgcat gaaaccgccg
     1921 gccgcactaa ttccgatgat actgacacgt tttggtccta attgcttgac caataacatt
     1981 ccaaaataac taagcaaagc accactcata ctataaagga atgtggaaat cgttccgcct
     2041 agcaaagtag tcaggaatag tcgtagccaa agtagtaaga agctgtctcg ttttttcatg
     2101 gtaaaaatgg caacgatcgt gattagattg gctaagccta gttttgcacc aggcgcaaaa
     2161 gaaaaaggat aagggatcat attttccaat aaaccaatga tcactccttg tgcaacaagt
     2221 agcgaaatat aaatcatttt ttgtaattta ctcatggtgt gtgaaggtct aataaatcag
     2281 actgtcttcg tcacctccat ctgttgaacg gacttcgatc actaatttat gtggcaaaca
     2341 gacgatggtt tcgccatttt tcgttgccca gcctcgacgt acgcagatct ggtcatcgca
     2401 atctgcttct tttatccgta ctcgatcgcc atctatctcg atcaagttat aatctccgtg
     2461 ttcatctttg taagtatatg tgttgctctc ttctccagcc atcaaaggga atgttttgat
     2521 ttctgtgcca tccacacgca gtaccgcttc tttttctgct gttgcggtgt tttgctgaag
     2581 accaaaaatc atgactggta aaaaagaaag aacagtcaaa agcaaaataa taaaaacatc
     2641 ccaaggtttg agcagacttt tttcagcaaa ttctttaagg ctcatttttg ttctcctttt
     2701 tccagattaa ctcacccaat tttagcataa aaacaagagg ttgtgacacc tgtgtcttgc
     2761 tttgagtaat aagaacgaag aatagaaaac agctttccat gttttctaat tctttgggct
     2821 tattaccgag aagcagcagg tggaacaccg tttataacaa gaggttgtga cagaagtggg
     2881 caacttcaag aaataagaag gaatttacga aaattacttt tcaagttttt gtgaaatttc
     2941 ggcttatttt tcgaagaagc tacttctgga acaccgttta taacaagagg ttgtaacaga
     3001 ggttgtgaca cctgtgtctt gctcatggag gcttatctcg ggcatcttat tcctttaatt
     3061 ttacataaaa aggaggctgt gacggtttgt ctcagcccct ttctattgaa atcttgcatt
     3121 caaataacgt tctttatcta tttatttctt gccgtactgg gaacttggtc taccgtacca
     3181 ccaattacct agtgtacgtt gtagccatgg aattacccag cgatccaacc caatcgcacg
     3241 tccggaaccg ttcatcaatg cgaaagcaac aaaaatgaac caaatgttta cccagtaaaa
     3301 catgcctgat aagcagaacg tgatcaccaa tacaatcgtt gtcgcactgc atagccatgt
     3361 gaataatcca gcaatcaatg ctaatgccaa ggcaatttca aagaatacca tgaatttttg
     3421 gaagaacatt gctacatcat tgtttggcat gatcacttgc atgatctttg tgaaccagtc
     3481 tggtgacttc tcaatcacag ccattggttc ttcaccgtat gcataactca aaccaaaatg
     3541 tgcagcttga gtcgctgctt ctccggcact tgcccctgct ccgctggcag ctgtggttgc
     3601 atcaccagca gcagaagcac cactggcaac atctgttaca ttgtattccc atgtccaagg
     3661 gaacacactg tttccagtga accatgatcc ttcaccaaac caagtacttg gtttgaacac
     3721 ttcaccattc ccaatgattt ttttggaagc ttcaacgaac caaactaaac catagaaaat
     3781 acgaagtggc acactccata agacattgcc gtaacgagaa gaatgtcctc gagtcacgtt
     3841 gcgatcatct ttgatatgga aaaactcatg cattaaatat tggaacatat aataaccaga
     3901 acgaatatca aagaagtatt tcaaattcac gatatgtttc attacgatag ctaaaaatcc
     3961 gcttaaatgg atcttatcaa ataggttagc taccccccat ttggcaccaa tagaaaccat
     4021 aaatccttga tagtttcctt taaatttatg cttttctccg cctttgatcg aagccacgat
     4081 attcgctgcg gctgtgtgtc ctgtttgttc agcagcttga acgatctgcg gtgtcggtgt
     4141 tcctgggaat tcttcataaa agactaaatc accaatgata tagatgtttt tatcttcgta
     4201 gccttttgcc tgcatatatt cattggcgat caaccgctgt ccgcgtgctg attctaatcc
     4261 aaagtcagca gcgtcagaag ttcctttgac accagctgtc caaatcagtg tgtgagtcgg
     4321 aatgttgcgt ccgtctttca atttgatatg atcagcagcc acttctacga ttggtgcatt
     4381 caataataat tccacgttgt gcttacgcaa atagcgttca gcttttgcag catcatttcg
     4441 atccaacata ttcaagatcg tcggcattgc ctctacgacc atcagtgtga tttcgtttgg
     4501 atctaattta taatctttgg ctaggcgatt tttccagtcg atcagttccc caatcatttc
     4561 aataccggta aatccagaac cacagacaac gaaagtcagc atggctttac gcagttcatc
     4621 atctggttcc aatgcagctt ttgctactgt cttctcaata tgttcccgaa tccttacaga
     4681 atcttcaaat gaccaaaggg tgaatccgtg tgctttgaca ccaggtgtac caaagtcatt
     4741 cggctctccg cccattccaa ggatcagctg atcaaaagga taggaaccta atttggtctt
     4801 gacgattttt cgttctttat cgataccgat tacagtgtct gtgacaagtt gtacattctt
     4861 ttgacgagca aacaaatgct gcagatcgta ttggattgct tctggttcta cacgtccgcc
     4921 agctacttca tgcaactcgg tcatcatagt atggtacgaa tgacgatcga tcagagtaat
     4981 tgctacatct tcttttttca gtttctttgc caagtatttt gtagctgaaa caccggcata
     5041 tcctgctcct acaacgacaa tattttgctt tgccattgat catccgctcc ttatagacta
     5101 tctatataat gaatatatga taattctttt agtttgatac ttattacaca atctccatat
     5161 attatataga tgttctgttc ttttgtctaa ctccttttgg atttttttca aattttaaaa
     5221 taaagcgttt tttcacgaaa tttgctgaaa gaaaacgttt gaaatattac atgggttatt
     5281 tatcaaaaat agttgactta taggctaaaa agattagaat gtataatgaa tcacaaagaa
     5341 aaattgtgga ctagaaatgg aatggtgggg tattaaaatg aagaaaaaac gttttgtaac
     5401 tggatttgcc gtattagcat tttcagctct agtgttaggc gcttgcggcg cagatgacaa
     5461 cggaagctca aactcttctt ctgaatcatc tacagcacaa tcttcgactg caaaaagcac
     5521 aacagaatca tctgcaaaag ttgtagctgg cggagatttg caagacggca catataaatt
     5581 agaagaaaaa aattattcaa atggttaccg tgcagtcttt gaaatggttg taaaagacgg
     5641 caaaatcact gaatcaaaat atgataacgt caatgaaaac ggcgaatcaa aaacaaaaga
     5701 tgcagaatac aacaaaaaca tggaagcaaa atctggcaca aacccagaaa aatacattcc
     5761 tgagttgaat gaccaattct taaaagcaca aagcgcaagc ggtgtggaag tcgtaactgg
     5821 agctactcac tcatctgaaa gcttccaaaa ctacgcacaa caattgatcc aagctgctca
     5881 agctggtaac acagatacaa tcgaaatcga caatggtgct gatttgaaag acggcactta
     5941 caagcttgaa gaaaagaact actctaacgg ctaccgtgtg caattcgaaa tgacagttgc
     6001 tggcggcaaa gtaactgaat caaactttga ttatatcgac aaagacggta aatcaaaaca
     6061 agatgataca gaatataatg aaaatatgaa agcaaaaagc ggtacagaac caaaaactta
     6121 catccctact ctgaacgacg aattcgtcaa agcaatgggc gaagaagatg gctcacctgc
     6181 taatgtagaa gttgttacag gtgctacaca cagctcacat tcattcatca tgtacgcaca
     6241 acaattagtg aatgcagctg aaaaaggcga cactcaaaca atcgaagtag ataatatcgt
     6301 aacagaaaaa taatcacata atcatactaa taaaagttgg agggtgggac gatagccaga
     6361 ttaggcagtc gtctcacctt tcaaaatgaa gagaggaaaa agatgcggaa aaaactacta
     6421 ttttccttaa tcacactggg catctctttt atggtgctaa ctggctgcag caactcagca
     6481 aataaaacaa ccactgaaag ttcagcagct accaagatat tgaaagatcc atattctgat
     6541 gaacagttct tgttagggac ttacgttcgt atccgtgtgt atgatgaagg caaagaatca
     6601 gcattgaaac ctgccttcga tcgagtaaaa gaacttggtg ataaaatcac gatcaatcaa
     6661 aaaggttctg agatcgatga agtgaatgag caagctggga tcaaaccagt aaaagtttct
     6721 gatgacgtct acacgttagt caagcgggcc tacgaatata gccaagattc tcaaggcgga
     6781 ttcgatatgg cgattggtgc aatcacacaa ttatggcgaa tcggttttga tgacgccaga
     6841 aaaccttccc aagaagaaat cgatcaggca ttgaaattag tggattatca taagatcgaa
     6901 ctaaatgaca aagaaaaaac tgtttatcta aaagaaaaag gaatgatcat cgatttaggt
     6961 gcaatcgcca aaggttacat tacggacgaa gtagtgaaag tcttgaaaaa acaaggagtg
     7021 accactgcca tcgttgactt gggcggtaat gtctatgtct taggccacag cccaagaggc
     7081 gaaaaccaag actggacagt cggcatccaa gatccgaaca tggctcgcgg atctgtttta
     7141 ggttctatta aagaacggaa caaaacatta gttacctctg gaatttacga gcgttattta
     7201 gaagtagatg gcaaaaaata ccatcatttg tttgatccaa aaacgggtta tccgttcgac
     7261 aatgatatcg caagtgtcac gatcataaca gataaatcaa ttgatggtga cgggttgtct
     7321 acagcagtct tttcaatggg tgtgaaaaaa ggactggaat acgtcgaaag cgaattgaat
     7381 aacgggacgg aagcgatctt cgtgacaaaa gacgataaag tatatgtgac cgatccaatc
     7441 aaagacacct tcaaattatc ggaggactcc cattacacga tgggtgaccg ttctgaacta
     7501 aaataaggag tacgaaccat gacactaaaa atctttttag aagtagttga aatacgaaca
     7561 aaggtggcta gtgtatttcc ttttgcggta ggggtattat tctctatcgc tttttttcat
     7621 gagatacatt ggctaaacac ttttttattt tttattggaa tgctagtttt tgatttagcg
     7681 actaccgcta tcaataatta catggattat gaaaaggctc attctgaagt atataagtat
     7741 gaagaaaatg tcattggccg cagaaatcta tctcctgtat tgattcgaaa catgatttta
     7801 gctatgattg catttgtttt tgttatcggc gttattctaa cgatcaatac gggttggctt
     7861 ttacttttga tgggatttat ctgttgtttt attggagtat tctatacatt cggaccgatt
     7921 cctttatctc gaatgccttt aggggaaatt ttcagtgggg tgactatggg ccttggaatt
     7981 tttgccatgg tcgtttatgt caatacattc ggttcagatg tctatgatct gacagtcaac
     8041 ttttcatctg gacaatttgc tttggtagga aatctttggg ctatagcagc aatcgtatta
     8101 gcttccttac ccttggtgtt tacgattgcc aatatcatgt tggctaataa tttgcgggat
     8161 cttgaccgtg atattgaaaa tcatcgctat acactagttt tttatatcgg acgtcctgcg
     8221 ggaacagtct tattccagct attgatgtat gcttgctatt tcgtgatttt aatggggttg
     8281 ttgagcggta tctatgaatg gccgatcttg gtcaccttct tgaccttgcc aattgtgaag
     8341 aagcatttgg atcaattcaa gcaaacgtta ccccagccta tcagtttcag ctattccatc
     8401 aaaaatatgg tcttattcaa tgccagttat gtattggggc tattactaac aatcattatg
     8461 caagccattt aacagcatga agaggttgtg aaaaaactgc cctgcatcaa gtaataagaa
     8521 cagccaaata aaaatagctc cttatatttt tcgtttggtt gggcttatta ccgcagatgc
     8581 aagcttttga acaccgttta tcaggaggtt gtgaaaaagt cgcttagttt cgagtattaa
     8641 gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttggctta ataccgagaa
     8701 actggctttt gaacaccgtt tatcagaggt tgtaaaatca gtgttttgtc ctgagtatta
     8761 gagaaacaaa tggaaaaata gttcctcata ttttgccgtt ttttgagcta ataccgaagg
     8821 acagctgatt gaacactatt tgttcggaaa aagtgactaa ctatgacaca atttttttca
     8881 cagtcccttt tttcacttga tttgattcgt accagcgaac ttgacgagaa ctttcttggt
     8941 ttggtaacta tatggtattc ttttaacatc ctcgtttgct tcttctaatt tatttataca
     9001 aagtcacact tttttaaaca tctgttcttc gatacatttc tatttctttt aaacatcgat
     9061 accaatattt tgaacttaag agtgcatacc aaatggattc atttactctt cgtcagttac
     9121 gaagataatc aaaatctcca acttccctac ttatttcgtt ttgagaatta tcgaagcaat
     9181 cttacataaa taactaaaaa acaaaaaacc agaaaatcag tatactgatt ttctggtttt
     9241 acatggtttg ttcaataaaa agctgttgga actgttaata ttaaattatc gcatcgttac
     9301 gaattcttcc gctcctgttg gatggatggc tactgtattg tcaaagtctt ctttagttgc
     9361 acccatcttg atagccacgg caaaaccttg cagcatctca tcgacaccaa caccaatagc
     9421 atgtaagccg acgattcttt cttcttttcc gacacagatc aatttcattt cgcatttttg
     9481 gcgataatca tttaatgcaa agtacattgg ggtaaagcgt gaacgataaa ctttcaattc
     9541 attttcgcca tatttttcca atgcttcttc ttctgtcaaa ccaattgttg caattggtgg
     9601 atgcgtaaag acgactgtcg gaacaagttt atagtcaaga taagaatctt tctttccatt
     9661 aaataaacgt tctgataaac gtctaccagc tgcgattgca acaggagtca gatctaattt
     9721 accgatcaca tcaccaacag caaaaatatg ttcatccgtt gtattttggt atttatctac
     9781 tttgataaac ccttttttgt ccaattccac atttgtattt tccagaccta atttttcggt
     9841 attcggtaca cgtccaccgg caaaaagtac acaatcacca gttaaggttt caccattttc
     9901 aaatagcacc gtatattcgt cattgttttt agtaatttct ttagcaatat gatgtgcgta
     9961 agtttttatt ccagcttctt ggtacatttg gatcaaattg tccgaaagca ttttatcaaa
    10021 cgttctaagt ggtcgttctt ttcgatatgc ccacatgact tcactaccta aaccacgaaa
    10081 tacacctgaa agttcagccg caatgtatcc agcacctaaa acgattgctc tcttaggtaa
    10141 ctctgttaat tcaaaaaatc catttgaatc aattgcgtat tctccaccag gaatggtcat
    10201 tttacttgca cggcctccag tagcgatcaa gattttagga gcacgatagg tttcaccgtt
    10261 tacttcgatc gtttgactat cgataaaagt agcgtaacct tttatagcct cgacatgatt
    10321 gctatctaat cctctttgat aagcaccgtg tagaaaatca atatattttt ctcgtctttc
    10381 tactagaccg gcgaaatcaa cattttttaa atctgcttgg ataccgtaac ttgaggcatc
    10441 tcgttcaatt gtttccaaaa tcgtacttgc ttgccacata acttttttag gtacacaacc
    10501 gacgttgaca catgttccgc ccaattcatt cgcttcaatc agcaaaactt ttgcgccatg
    10561 catccctgct ctgtttgctg aagcaatacc gccagagccg ccaccaatta cgatgtaatc
    10621 atatatttgc attttgttcc tccttattga agagatcaat caaaaccttt atttaacgat
    10681 cctttttcta cagaaaacaa gtgtaacact tttcttgaat tttgtatgcg aagatgctta
    10741 aaacagggat atatcagctt tttccttatt tacgttttcg gatcatatct ccaggtttca
    10801 ccggctgtgc gactggcata gttaaaatca tcattggatt tggtgctcgg tcaatggatt
    10861 cgccttcttc attatgcata acttcaacgg tttgactgaa atgactgaat cctggaccat
    10921 aaaattcgat ttcatctcct acagaaaaca agtttctctg acgtatcgta gcaatctgtg
    10981 ttgcctcatc ataagataat acttcaccga caaatttata tactgggatt ttacgacgtt
    11041 caccgaataa ttgttcgttt tcagttggtg tattgtagta aaaacctgta gctaattctc
    11101 gttgtgctac tttccataac tcgtcgatcc attcttgctt gcagacatag ttttcaggat
    11161 cttccatata actgtctaca gccgctttat agacatttga caccgtagat acataatgga
    11221 tcgatttcat tcttccttcg atcttgaagc tgtctacgcc gttttcaatc aattctggaa
    11281 tatgttcgat cattgacata tccactgcac tcatcgagaa ttcttcttcc acttcgcctg
    11341 tatcagttaa actgtttcgt tcttgaccaa aaggcatatc gaacaatcca tacttccagc
    11401 gacaagattg agaacatccg ccacggtttg catcccgcat cgacatatgg ttggacaatg
    11461 tgcatcgacc agaataagag atacacatgg caccatggat aaatgcttcg atttcggtat
    11521 ccgtattttt acgaatctct gccacttcct ccattgaaac ttcacgagct aaaacgacac
    11581 gttccaaccc ttcttctttc cagaattcca atgtctcaaa attagttgct gaagcttgag
    11641 tggataaatg gatcggcaga cctggggctt ctgtcgcaca aatttcgatc aaagctggat
    11701 cagaaacaat cactgcagaa ataccgacat cacgcaaact gcggaaaaat tcccctgctc
    11761 catcttcatt tccttcatgg gtgaccatat tagcagcaac gtataccttc gcatcatgtt
    11821 cttttgcaaa agcaactcct tcagccattt cttcataagt aaaattacct gcacggcttc
    11881 ttaaaccata tgcattcccg ccaatatata ctgcatctgc tccataatgg atcgcggttt
    11941 ttaacttttc cagtgttcct gctggcgcta ggatttctgg tcgtttcaat tttcttttta
    12001 ctgtcatttc tttcatcata ctccttattt gatagcagaa ggatcaatat aaaagaatcc
    12061 tgtatctaat tcacggtttt caggatgcaa tttactgatt tcgctagtca ttttttccgc
    12121 tttttcttga tcccagctac cttctaaaat ttgttttttt gcttcggcga atagtcgagt
    12181 gatgtttacg aatttttcgc ctggagtaaa taatccgtcc aatttccatg tacagtaatg
    12241 atgctgataa agttcattca attcattcga gagattcaga tcattgctgg caaaaatatg
    12301 tgtgccatga ctatcttcat aaatagaata atgtgtctct tcttttttag gttccgagat
    12361 aaaaagacct ctttcacgat ctttttgttc gtcttgtttc gtatagttat agtaattctg
    12421 tagcagtgga cgtttggatt gatggatgca tgtagcacca tacacaaggg tttctacagg
    12481 aatatcgagt ttttcttcca tcgccttcat ctcttcaaaa ggaacttcac gagcaagtac
    12541 tgctccaact gcgccttttt tcgcccagaa attgatttga cgtgcgctcg ttactaatgt
    12601 ttcagcatca taaatatacg gtatacgcaa ttcaggattt tttttcatcg tataaataat
    12661 acctgtatca ccaactgtga tcacatctac gtttatttct tttaaaaaag ccaaatattc
    12721 aggtacattt ttcatttttt caggatgaat gatcccattt acagcaatat tcgctttttt
    12781 accatacttg tgtgctaatt ctaccaattg tcgctgttct tctcgtgtaa atgaagcagg
    12841 cagacgcaat ccaaattgct cttcaccgaa atatagtgta tctgcacctg cagcaagcaa
    12901 ctgttctgct tgttcaatag tttctactgt ggttatgagt tcgatcataa ttttctcctc
    12961 ctacaacttc ataatagtag catagctcta aaaactttcc aatacttctt ctatttaaag
    13021 tcggattttt gaaaattatt tcacaaaaaa tcaaaataaa gttcgatata ttctgtccaa
    13081 atataaaaag agattgtgac aaaaatcttg tcacaacctc ttaatcaagt cttactatta
    13141 taaaaattca gctacacagg ccaagtaact atagggaacc tactgtttcc tttttaggtc
    13201 cgcgaacatt caatgtgatc ttaccttttg aagcacctac tgttacgtgg tcacctaaac
    13261 gaatttctcc gccaagcaaa gcctcgctca atcgatcttc aatttctttt tgaagtgcgc
    13321 gacggattgg acgtgcacca tattcaggat caaatccagc tttcccgatc acatcgattg
    13381 cagatggtgt gattttcact tgaatatctt gttctttcaa tcgtttgata atcgctttgc
    13441 tcatgatttg gacgattgta tggatttcat ctttactcaa tgaatggaag acgacagtct
    13501 catcgattcg attcaagaat tcaggtcgga aagctttctt taactcttct aagatacgtt
    13561 tttgcatggc tttgtgatct ttagtaacat cttggacatt gaatccgaca tttttttctt
    13621 ctcgaatttg tgtcgctccg atatttgaag tcataatcat gattgtattt ctaaagtcca
    13681 cttttctacc tttagaatct gttaaatgac catcatccaa tacttgcaga agtaaattga
    13741 aaacgtctgg atgtgctttc tccacttcat ctaagagaat cactgaatat ggtttttgac
    13801 gaattttttc tgtcaactgt ccaccttcat cataccctac gtatcctgga ggagacccga
    13861 ttaatcggct tgtactgtat ttttccataa attctgacat atcaacacgg atcagggcat
    13921 cttcacttcc aaacatgact tctgaaagtg ctttggccaa ttctgttttt ccgacaccag
    13981 ttggtccaag gaacatgaat gaaccaattg gacgatcagg atctttcaat ccgcttcgtg
    14041 cacggcggat cgcacgtgaa actgctttga cagcctcatc ttgaccaacg acacgttcat
    14101 gcagaagtcc ttccagttct aacaagcgtt cgctttcttt tttctccaac tgctgtagag
    14161 ggacaccagt ccactccgat acaactgtag caacatcttc ttctgttaca cgatcagaat
    14221 aaccttgctc ctgttttgct tcaattgcag aaactttttg cagcttttta cgtagtgctt
    14281 tttcttgtct gcgtaattga gcagcatttt caaagtcttg tttttggatc gctgcttcct
    14341 tttcttgtac tagttcatcg atttctagtt tgatcacagt tgattttgtt aagtgatcgg
    14401 tttgatccaa acggactttc gctgctgatt catcgatcaa atcaattgct ttatcgggta
    14461 gttgacgaga agtgatataa cgaacagaaa gattgactgc tgctcgtaca gcttcatctg
    14521 tgatctccac tccatggtgc tcttcatatc ttgtacgtaa tccttgaaga atcacttctg
    14581 cttcttcagg agttggctca tctacttgaa tgcgagcaaa acgtcgctct aatgcagaat
    14641 ctttttcgat atatttttga tattcatcta gggtcgttgc tccgatcgtt tgtaattctc
    14701 ctcgagctaa cgccggtttc aagatattcg aagcatcaat tgctccttct gctccacctg
    14761 caccaattaa ggtatgcaat tcatcaatga ataagattac ttgaccatca ttatagattt
    14821 cgtcgatgac ctttttcatt cgatcttcaa attcaccgcg atatttcgta ccagcaacca
    14881 aagatcccat atcaagcatc atcaggcgct tttcttgcat gtcttctggc acttcaccta
    14941 aaatgatttt ttgagctaac ccttcagcaa tggctgtttt gcctacacca ggttcaccca
    15001 ccagtacagg gttattcttt gtccgtcggc taagaatctg gataagccgt ttcacttctc
    15061 tcgaacgacc aacaactggg tccagcttgt tttcttttgc taatttcgtc aaatcacgtg
    15121 ctaatgaatc tagcgtaggt gttccttgcg gtgtttgccg tttatcttgt acatttacat
    15181 ttctacgacg attcattcct tttccagcag aatcaccagc tagccccatt ttttgtttca
    15241 gaacttgacg ggcttttgaa aggctgatac ctaagttgat catgattcga gtagccatga
    15301 tactttcatc ttttaataag ctcatcaaaa tatgttctgt tccaactttt tgagaaccag
    15361 ttttcttcac ttcgctgcta gctaaagcaa aaacttgttt cattcttggt gaatatggaa
    15421 gaaagactcc tttagggtaa gaacggatac caccataacc aatcagatgt tcaatttctt
    15481 cataaatttc cgtttcattc aaatccattt cacgtaatac ttttccagca attccatttt
    15541 gctcgaccac taaggctagt aaaacatgtt ctgaactaac tgattgatgt ttcaaccgtt
    15601 ttgcttcttc ttgtgcaatt tctaatactg cttgggctct ttcagtaaaa agttcttcca
    15661 tctaatctca cttcccatct tcataactta aacgttccag aaatgctcgg agaatccgag
    15721 cacgtgtatg atcttcatat tcattgaaat tcaatgtgtt ttttgcaatt gcactcaaca
    15781 tcaagtttcc ttcttttttt gtaattattt ggtcttcata aagtttttga ataatagcaa
    15841 aagcattttt ctcactgatt gtatcatcaa ataactgatt tatctgctca agtaattgtt
    15901 ttttatctga aatccttact tttgcaattc gtatataacc accaccacca cgtttgcttt
    15961 ctactagata accacgttgg atggtaaaac gggtattaat cacatagttg atttgtgaag
    16021 gaacacagtt aaagaggtct gccatttcaa tccttcgaat ctcgatcatt tcactatttt
    16081 ccagaatttt ctttatatat gattcaatta aatccgaggt attctgatgt gccatcttat
    16141 tcattccctt tgactaatat tgaccttaat tataacgaat ttgataatag aaagaaagaa
    16201 gaacgctttt tgttaaataa atcctttaga atcaacaaaa aaaaatacgg aatatactat
    16261 tccgtatcga cgcgcccaag aggagtcgaa cccctaacct tttgatccgt agtcaaacac
    16321 tctatccagt tgagctatgg gcgcatattc aatttaaaaa aattataaat catttgaaaa
    16381 caaaaagcaa gataaaaaaa atcgggaaga caggattcga acctgcgacc ccttggtccc
    16441 aaaccaagtg ctctaccaag ctgagctact tcccgtttaa aaaataaaaa agac
//
LOCUS       DADLIO010000054        16405 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.056, whole genome shotgun sequence.
ACCESSION   DADLIO010000054 DADLIO010000000
VERSION     DADLIO010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16405
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.056"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            4..243
                     /locus_tag="JOX41_002025"
     CDS             4..243
                     /locus_tag="JOX41_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449747.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKEVFKALSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            310..519
                     /locus_tag="JOX41_002026"
     CDS             310..519
                     /locus_tag="JOX41_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449748.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKTMKQKHLKRLSVAQYINDMQLT
                     GKEKACLLGSMKNFEQLRRTYRIHF"
     gene            579..1250
                     /locus_tag="JOX41_002027"
     CDS             579..1250
                     /locus_tag="JOX41_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HAY6449749.1"
                     /translation="MKKWLFGFLGVTLIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVLAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            1303..3279
                     /locus_tag="JOX41_002028"
     CDS             1303..3279
                     /locus_tag="JOX41_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAY6449750.1"
                     /translation="MAINRYVKKAGMLIGMLGIIAGCFQGYRAYAEDITQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PTEDSDLTNAKVDEIVKDVEDKGSNSEYVKNATNKITSAVDENGEITFADQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDNTGSGFLKDIHLYPKNIVSKLSFELTK
                     FGDDGTAQSKQTPLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDKEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GQGLSYVAAKANIKVTNKDGSVVLKENTDYKIQNSENGFVIDFIVNNGQVSDTVASLH
                     GQDLQMTYNMYVNDSAAVANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLVDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGEYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQTYVLISCLLLGAGALSAVVYFKKKA"
     gene            3294..4046
                     /locus_tag="JOX41_002029"
     CDS             3294..4046
                     /locus_tag="JOX41_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAY6449751.1"
                     /translation="MIIRKPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQ
                     QIAAIDRTGTAAETDSSLDVAKIELGDPVGILTILSISLKLPIYDGTSDKILENGVGI
                     TEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIE
                     EVQKDELQRNFVTYLEPNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEEN
                     KKQKLSWKWLLGSTVFLSVMIIGSLFVYKKKK"
     gene            4062..4823
                     /locus_tag="JOX41_002030"
     CDS             4062..4823
                     /locus_tag="JOX41_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449752.1"
                     /translation="MRNRKWLFVCAAALFSFTAYTQLTFADRQESTDSTEQTIQTSDS
                     STIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGQKLEKQEGV
                     NGAKFSVYDVSDILQKMDVKDLTTDQIESQLKDRVKKLSSDQLKLISNGETKTIDQQT
                     GVFEFSVEVQANQKQAYYIVNESSPENISNSEDILLLTPVSDKNGEFLKDVWIYPKSE
                     ASQPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            4836..5096
                     /locus_tag="JOX41_002031"
     CDS             4836..5096
                     /locus_tag="JOX41_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449753.1"
                     /translation="MKLIKLLLFNFSCLTAVFLYCGLLFSKLSILPSYQLYLMRILNI
                     PAASMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG"
     gene            5093..7183
                     /locus_tag="JOX41_002032"
     CDS             5093..7183
                     /locus_tag="JOX41_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAY6449754.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKTNITVNGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYP
                     SFQKEYGETNLVLEGVTTNTKVNIDYGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNLL
                     DNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATYEDG
                     SPVQFSGDTFISFNSLNPAGGKSTDLKGEYAHYDKMNTTDWYVRKDTVLSEFKSFYNN
                     LNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQT
                     WFTLSSATIFSVVPDQPEKTGVDKNGNNVNDKMLQVGDTIQYRIKQKVNRLGVDLLAV
                     YDRFELIDNLPKEVNYVDAHVESGTNKKFDVSGEVTYDKTKHQVKYAAKADTLKNRMK
                     YNGETYELVINVKVNELANQNSVAKNQGTSIINKVEKDTNIITVYFPKIPVKEVQQNG
                     KDVNGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDPIEARLT
                     YKEGSAQVIDKSKGKDITSEGTLTYDSNSRTLKWEASADFLSNNLLDGREIQLIFTAK
                     TPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTISAVSLLL
                     LVLATFSYAVLRYI"
     gene            7210..7674
                     /locus_tag="JOX41_002033"
     CDS             7210..7674
                     /locus_tag="JOX41_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449755.1"
                     /translation="MKKLIIVVTSLIAMIVILVGCSNEKNKQINQDNGVLKSGTMWKE
                     EVGGLVYNLKIIDETTWEYSESVWHPDPVQITVKRQKDYKGLERYKIVDSAGVREFIN
                     KSDSLFIVVPYEKNGVKKIIFLGSSKDEKRTKEKLIHDGSQSNKYKLQKTSE"
     gene            7671..7913
                     /locus_tag="JOX41_002034"
     CDS             7671..7913
                     /locus_tag="JOX41_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449756.1"
                     /translation="MIASLFICPEGGITVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            7931..8233
                     /locus_tag="JOX41_002035"
     CDS             7931..8233
                     /locus_tag="JOX41_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449757.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAAAA
                     VASIVIGGLFFLFGRRGAENGKMHVGYVLMGVGVILAAASIVVSLFGLFGQTPQGL"
     gene            8303..10366
                     /locus_tag="JOX41_002036"
     CDS             8303..10366
                     /locus_tag="JOX41_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449758.1"
                     /translation="MYFTIAGNTKTDKELIKKATKEVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGKVLEHESRSSVKLTLTLHDTEGKIEKAGTEYVFGPLDYQISEGFYPTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVNQGSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETAEVEVDPVEA
                     NEESTWTEGDSQEYIEPLISEEVEKNEIEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKAKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCVA
                     KINNFTQTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMEKYEKIQQELQVQIPKWKKEYEIQQQELKEQEEKQRQKEKEREQLELKKREQD
                     LAEQQMAIEKQRLNQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPTPSVAAVQTPM
                     NNQTNLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTTSIKEE
                     AQEQARKEYEQQLEELLNRTNQSTTESSMENSKESDPSKAKEGSSDSTVQSNTSESSE
                     SNEVK"
     gene            10366..12975
                     /locus_tag="JOX41_002037"
     CDS             10366..12975
                     /locus_tag="JOX41_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HAY6449759.1"
                     /translation="MRVRETTRRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     QKIFYSGLAYLPLNYVVTRIPEAFHRFEIIPGSLQGVNIFQLQEMPQLFHFDSTGFWN
                     PLTPTTSLGTRLVVSTICVVPAVLMGLKMDMWFRPLADGQKGDNRLKTLKEIQQIYPQ
                     IPESKGGFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     RQSSMVVNDPKTELYVASKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYQDPDNEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNIL
                     STAITGLNPFTLTKIAKMTSQSTIDYKSIGFPKYLDLKLHESLLNQRIVVEFYHQGKK
                     FHEERVKVGYRGFCEINFDCHLEQGDHVCLKYDHRGKEYVAWYEFSQRVLKDEEGNIV
                     YRKKRGETHLPELEKEAVLTLDEDKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHII
                     VSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNMLW
                     DLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENST
                     INSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNHG
                     ETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDIYARRLYHNMH
                     DQIEEEAKENIFIKIVQSLDNSTAQKLLIQFYEEKQIDRLQEYLEKLRQNEEITEVIR
                     KRLLLEAEKAVKE"
     gene            12972..15497
                     /locus_tag="JOX41_002038"
     CDS             12972..15497
                     /locus_tag="JOX41_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449760.1"
                     /translation="MIIGGIFSGIADWWSGLFGDGDADPKTVTKVLQDYGNYLQYQDV
                     FSWICNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNELFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKIKNILVNLFMAMILIFGGSSLIDEGLNISKNFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLENDPNKVEHIPTDKRNALTAKNFKTANINGIIT
                     PDQAKKMSESSDISTVQKDRLKALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYRRY
                     ISSPGIILAGESSLSVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSAIE
                     DISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQSV
                     TKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGFGH
                     RKDVTPDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGTAE
                     DLTEKAKDTLEDKLDGTRAKELAEAVKNPSEALEKQKEKASEVKEGLKDAYGEGQVNA
                     AVKANTTTEKENQEGIVIPSVKDHQEALHSNENSIEEKNSIEERNSEEGKNGQLPKTD
                     PEQYRYKPNSDLENEKRISDLSKVNQEDKAENEGQLPKTDPEQYRYRSVNSENEKRIS
                     DLPKRNQEVQTDEDSIVLPNDNGIEVGTEKSTKIGLPKAQNLPMKDSRLNQFKDNDQS
                     FVHQSPAGTVQMKPSRLPENGNLTTVSYNLSESGETGNASVQNVVTREAAPKPIQNVH
                     TGYKPANVAFTAPTKINVTRETKNRNNALKEQLLRDIKQDIKP"
     gene            15549..15881
                     /locus_tag="JOX41_002039"
     CDS             15549..15881
                     /locus_tag="JOX41_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449761.1"
                     /translation="MDKYSNMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKMVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFADKNHYHALDPNRNY
                     HGTYKEDE"
     gene            15882..>16405
                     /locus_tag="JOX41_002040"
     CDS             15882..>16405
                     /locus_tag="JOX41_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449762.1"
                     /translation="MRVKGQNSVERKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLKKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILG"
BASE COUNT         6085 a         2575 c         3323 g         4422 t
ORIGIN      
        1 tagatggcgc gaccagtttt agaggcgatg gatatggata ctttgacaaa aggaaggtat
       61 gtacagctgt tagctcgtgg ttattcacct aaagaagtat tcaaagcctt atctaaagga
      121 acagatatgg aaaaagaaag attgcgaaaa gaattcgatt attggagaac ccataatgga
      181 atcaaggatt tgaaaccagc acggccagta attaaacgaa agaaaaagat aacccaagac
      241 tgaagtgtag agcgtatgtg atcataggct tttttatttt tgcaaaaaac aaggaaggta
      301 ggaaaactca tgaattatga agaaatcgaa aacagaaaaa aagtgtcgaa agaaatggaa
      361 gaaaagttac taaaaacgat gaagcaaaaa caccttaaaa gattatctgt cgcgcaatat
      421 atcaatgata tgcagttaac aggaaaagag aaagcttgtt tgttaggttc aatgaaaaac
      481 tttgaacagt tgagacgaac ttatagaatt catttttaaa actttttcta tggaaatgag
      541 aaaaagtttt tttgttttgt ctgaaaggag gcagatggat gaaaaaatgg ttatttggtt
      601 ttttaggagt cactttaatc gtcttttgca gtgtgtttgg ctatgttagc taccaaaaac
      661 atgaaggaga ggtgtttaag caaaatatag aaaaaaagat gcccgtagat caaatcaatg
      721 cacatgcaaa gagttataag gaggatgcaa cgaacgtcaa taatgatatg tctttggggc
      781 aaatgttgtc catacaaaaa gaagcaatcg aaatgggcgt caataaacaa gtacttgcac
      841 aaattcagat tcctgcactt ggtttagcat tgccaatttt taaaggggca aatcaataca
      901 ctttgagtct tggagcggct acttattttt atgaagatgc cgaaatgggc aaaggaaact
      961 atgtcctagc aggtcataac atggaaatgc caggtgtttt attttctgat attcagaagt
     1021 tgtcattagg ggaggtgatg gacttagtta gtaacgatgg cgtctatcgt tacaaggtaa
     1081 cgcgtaaatt tatcgtacct gagtacttta aattaatcga tggcgttcct gaagagaact
     1141 ctttcttgtc tttgccaaag aaaggagaga aacccttatt aacgttgttt acttgtgtct
     1201 atacgtcaca aggaaaagaa agatacgtgg tacagggaga gctacaataa caaggtttta
     1261 atcaacgcga gtcgttgaaa tatgaaatga ggagagtaaa aaatggcaat aaatcggtat
     1321 gtaaaaaaag ctggaatgct tattggaatg ttaggaatca ttgcaggctg ctttcaggga
     1381 tatcgagcat atgcagaaga tatcacgcaa aaaacgccac cagaaaaggt caatatcacg
     1441 gttcataaat taatgtacga tcaaggaacg caattgaatg ttgatattga cgggatcaaa
     1501 aacgatggtt atacgcacga tcaatatcct acaggtgtaa cgaaatacaa caaggcagat
     1561 tatggtgatg ttgagtttac gttaggaaat attacggatc aagtattacc gactgaagat
     1621 tctgatctaa ccaacgcgaa agtggacgaa atcgttaaag atgtagaaga caagggatct
     1681 aacagtgagt acgtcaagaa tgcaacaaac aaaattactt cagctgtaga tgaaaatggt
     1741 gagattactt ttgctgatca accagcctat gtcaattcca aagggaatgt atatgtggtt
     1801 tatgaaagta aatccgctgc tggattagtc acacaaaaag caaaaccaat ggttgtgatt
     1861 gcgccaatga ctgataatac aggttcaggt tttttaaaag acattcactt atatcctaaa
     1921 aatattgttt ctaagttgag ttttgaatta acgaaatttg gtgacgatgg cacagctcaa
     1981 agcaaacaaa cacctttaaa aggggcaaaa tttgagttat acaagggcga acctggaaaa
     2041 ggaacaaaat taggagatct tgtatcggat gatcaaggaa agctgactgc tactgatttg
     2101 acgttaggaa aatactattt tgtggaagtt ccttcagaag ttgtagtggg atcagataaa
     2161 gaaccaacag cagatcaata tttattaggc gcagacgctc gcaacgatgc gcacaataaa
     2221 ttaacctttg aaattacgaa tgatggcgtg acaagtgact taaaagcttc atacgtaaac
     2281 tataaagcac cagtgatcga taaaacagta acaaatggaa caggacaaga acattctttc
     2341 caaattggtg acgcagtaaa ttatcaagga acaattcata tcccaacaga cattgcaggc
     2401 ggagcagacg gtatcacagt aaacggagtg aaaagcgaaa cttctcctta cagtgtattt
     2461 aaatgggggg atacagcagg acaaggactt tcttatgtcg ctgctaaagc aaatatcaaa
     2521 gtaacaaata aagatggatc tgtggtatta aaagaaaata cagattataa aatccaaaat
     2581 tcagaaaatg gctttgtgat cgattttatc gtgaataatg gccaagtaag tgatactgta
     2641 gcaagtttac acggacaaga tcttcaaatg acttataaca tgtatgtaaa tgacagcgca
     2701 gctgttgcca atccattaac aaatagcgtg gatttcgttt ataacaacaa tccatttaat
     2761 caggaagaac accacgaaaa aacgaaagct gacgttgtga cttatggtgc aaaattctta
     2821 aaagtcgata gcggactatt tggaacagga atcaaagcaa caccgcttga aggcgcagaa
     2881 tttgctgcta aaaacgcaga aggaaaatat tatggtggat tagttgatac ggataaagac
     2941 ggtgtcaaag aagcagtatg ggtagacgat gtagcaaatg cagcgatcct aaaatcagat
     3001 aaagaaggtc actttgaaat cactggttta actgaaggtg aatattcact ggaagaaaca
     3061 aaagcgcctg aaaactatca aaaattaacg aaagagatct ctttcaaagt agacaaagat
     3121 tcatacaaag aagaaaaccg aatcacgatc aaaaacaatc aaaaagcttc cgtaccaatg
     3181 accggtagca acggttttca aacgtatgta ttaatctctt gcttgttgct aggagcaggg
     3241 gcactttctg cagttgttta ctttaagaag aaagcctaga aggatcaaaa ccaatgatta
     3301 tcaggaagcc taagaaaaag cgaatcatgg gtaaatggat cattgctttc tggttacttt
     3361 cagctgtagg tgtcttactt ttgatgcctg ctgaagcgag cgtggcgaaa taccaacaaa
     3421 atcagcagat tgccgcaatc gatcgaacag gaacggcagc agaaacggat tcttctttgg
     3481 atgttgctaa gattgagtta ggcgatcctg ttggtattct tacaattcta agtatttctt
     3541 taaaactacc aatttatgac ggaacgtccg acaaaatttt agaaaatggt gtaggtatta
     3601 cggaaggaac tggtgatatt acaggaggaa acggtaaaaa tcctttaatc gcaggtcata
     3661 gtggacttta taaagataat ctttttgatg atttaccttc agtaaaaaag ggagaaaagt
     3721 tttatatcaa agttgatggt gagcagcacg cttatcaaat cgatcggatt gaggaagtgc
     3781 aaaaagacga actacaaaga aactttgtca cttacttaga accaaatccc aatgaagatc
     3841 gagtaacgct aatgacatgt acgcctaagg ggatcaacac acaccgtttc ctagtgtatg
     3901 ggaagcgagt aacctttaca aaatcagaat taaaagatga agaaaataag aaacaaaaat
     3961 tatcttggaa atggctttta ggaagtactg tttttctttc agtcatgatc attggttcgc
     4021 tatttgttta taaaaagaaa aaataaagga gggtaaccaa catgagaaat agaaaatggc
     4081 tatttgtttg tgcagccgct cttttttctt tcactgccta cacacagttg acgtttgcag
     4141 acagacaaga aagcacggat agcacagaac aaacaatcca aacgtcagat agcagcacga
     4201 ttcaaagcag cgatgaaacc gtcgattcgt caacagttga ttcttcagaa gaacctaaaa
     4261 ttgctgaaga cgatcaaata gtcaaacaga ccattcacgt tcaaaaaatt atttcttccg
     4321 aacaattaga caaccagggg caaaagcttg aaaaacaaga aggagtaaat ggcgcgaagt
     4381 tttctgttta tgatgtatcg gacattttac aaaagatgga tgttaaggat ctcactactg
     4441 accaaattga atcccaatta aaagatcgag tgaaaaaact atccagtgat caactgaagc
     4501 taatttctaa tggagaaaca aagacaattg atcaacaaac aggtgtcttt gaattctcgg
     4561 tagaagtaca ggcaaatcag aaacaagctt attatattgt caatgaatca agtcctgaaa
     4621 acatttctaa tagcgaggat attttgctat taacacctgt ttctgataaa aatggtgaat
     4681 tcttaaagga tgtgtggatt tatcctaaat cagaagcttc gcaacctaaa gaagaagtaa
     4741 aaaaaatcgt atctactggc gtaaagaaaa acttctttga gaattgttgg gattttgtta
     4801 ctcacttgtt ttctagagat taaggaagaa ataaaatgaa actgatcaaa ttattattat
     4861 tcaatttttc ttgtttaacc gcagtctttt tgtactgcgg tttattattt tctaaactat
     4921 ctattttgcc aagctaccaa ctatacctaa tgaggatttt aaacatacca gctgcttcca
     4981 tgccgctaga tattatggaa aagctcatta ggaatccatt atttactacg atcaatttga
     5041 tcgttattgt cggaatttca ctagtcattt ataaaaaaga ggggatgaag ggatgaattt
     5101 taaacactcg tggacaagac ggttaaaata tgtttttccc ataatgatga tgttaggtac
     5161 attgtttggg ttaaaaacag ccaatgtctt tgctgaaaaa gttattgtcg atccgtcaaa
     5221 tccaatccag aacgtaaaga ataattttat tattccaaaa gatgttccta atgcaaaaac
     5281 aaatattact gtaaacggag cgtcaaaagt ttacaaatat catgttgatg ccaacaaagg
     5341 tggttttaca gacgactacg taggattagt ggagggaaac aaaaatatac gctatccttc
     5401 tttccaaaaa gaatacggtg aaacaaacct tgttttagaa ggcgtaacaa ccaacaccaa
     5461 agtcaatatt gactatggaa aaatcggtac gtataacggg aaaaaagtca atatcaagct
     5521 agttctatct aatattcact tatactcgga tacgttgccg tggaatctac tagataacaa
     5581 ctatacaaaa actcattttc gagacgatgg ctataaaaat acgaatggtg caatgagtaa
     5641 atctaaaaaa agaacagtac tttggatctc agacaatctt ttctcaggaa ttgtttacca
     5701 ttcaacacaa atgaatgtgc agctagtagc cacatatgag gacggtagcc ccgttcaatt
     5761 ttcaggagat acatttatca gttttaactc tttgaaccct gcaggaggaa aaagcacgga
     5821 tcttaaagga gaatatgccc actatgacaa aatgaatacg acagattggt atgtcagaaa
     5881 agatacggtt ctttcagaat ttaaatcttt ctacaacaat ctgaacgtgg taggtggcca
     5941 cccaggagga agctctaagc tgacacaagc ggataatgat ttcaataatt tgcatgataa
     6001 attaggagat ccgaagtttg gtcaaggtac tgtgtccttt aaaatatctg aagcaaatcc
     6061 gacgtttgtg attggttctt ctaatgttca aacctggttt actttatctt ctgcgacaat
     6121 ctttagtgtt gttcctgatc aacctgaaaa aacaggggtt gataaaaatg gaaataacgt
     6181 gaacgataaa atgttgcaag taggagacac gattcaatat cgaatcaaac agaaggtgaa
     6241 tcgattagga gtggatttac tagcggttta cgatcgattt gagttaatcg ataatttacc
     6301 aaaagaagta aattacgtcg atgcacacgt tgaaagtggt acaaataaaa aattcgatgt
     6361 atctggtgaa gtgacctatg acaaaacaaa acaccaggta aaatatgcag cgaaagctga
     6421 tacattaaaa aatcgaatga agtataacgg cgaaacttac gaattagtga tcaatgtaaa
     6481 agtcaatgaa ttggccaatc aaaatagtgt agccaaaaat cagggaacgt cgatcattaa
     6541 taaagtagaa aaggatacaa atatcattac cgtttatttc cctaaaattc cagtgaaaga
     6601 agtacaacaa aatggaaaag atgtaaacgg acgaaatgac ggtaagaagg gtacgccgac
     6661 agctccttta aacgcaggat ctgaagtaca atatctagtc acacaaaaat ggcacacaaa
     6721 aggcgtagac gctgcgtcag atcactacaa acaatttagt attcaagatc caattgaagc
     6781 tcgtttgaca tataaagaag gttctgcgca agtaatagat aagagtaaag gaaaagatat
     6841 tacttctgaa ggcacactaa cctatgatag caattcaaga acgctgaagt gggaagcttc
     6901 cgctgacttc ttaagtaaca atcttttaga tggacgagaa attcagctga tatttacagc
     6961 taaaactcca ttacaatcag aaaaaaatat tgataaccaa gccgtagtag cagtagataa
     7021 tgtttctaat aaaacaaatg ttgtgacaat tggggttgat cctaacttgc cacaggtcat
     7081 tgttcctaaa acaggttcta cacatttagt aacgatttca gcggtcagct tactattact
     7141 tgtgttagca acttttagtt atgcggttct gagatacatt taaaataaaa aaacgaaaga
     7201 atgaataaaa tgaaaaagtt aataatagta gttacttcct tgattgccat gattgttatt
     7261 ttagtcggat gtagtaatga aaaaaataaa caaattaatc aagataatgg cgtattgaaa
     7321 tcaggaacta tgtggaaaga agaagtaggt ggtcttgttt ataatttgaa aattatagac
     7381 gagactacct gggaatactc tgagagtgta tggcatccag atcctgtaca aataacagtc
     7441 aagaggcaaa aagactataa aggtttagaa agatacaaaa tagtagattc agctggtgtt
     7501 agggaattta taaacaaatc tgattcttta tttattgttg ttccctatga gaagaatggc
     7561 gtaaaaaaaa taatttttct tggatctagc aaggatgaaa agcgaacgaa agagaaattg
     7621 attcacgatg gatcacaatc caataaatat aagttacaaa agactagcga gtgattgcta
     7681 gtctttttat ttgtcctgaa ggaggaatca cagtggcaaa agctaaaacg ccatttgaaa
     7741 aagccgcgtc taaaatctta gaacgccgcg gtgtatctga aacacagtgg aaacaagaag
     7801 tccttgaaaa agcacaattt gacctattac ggggaaaaga caaggactta gaaggatata
     7861 tctatcaacg tgaacgtgaa aagcttgttt tcgatgaaat tattaaacac taaaaggagc
     7921 gaacaatttt atgtttgaat caattacaat gaatttttta acacaaccga aagtagtagc
     7981 tgcggttgat atttttagag cattacaaac tgccgcaact agtttaaaaa acaatctgat
     8041 gatttttgct gctgctgcgg ccgttgcttc cattgttatt gggggtcttt tcttcctatt
     8101 tggacgaaga ggagctgaaa atgggaagat gcacgtaggc tatgtattga tgggggtagg
     8161 agttatttta gcagcagctt ctattgtggt ttcgttattt ggattgtttg gacaaacacc
     8221 tcaaggatta taagaaagta aaaaagtagg agtaagaagt agtcgatact ttttactcct
     8281 tttttatgaa aggagaatac tcatgtactt tacgattgca ggcaatacca aaacagataa
     8341 agagttaata aaaaaagcaa cgaaggaagt aggaaagcgt acttcttttt taccgaaaac
     8401 aattaaatat tctgtcattg aaacggaaga acagctacat gtgttaggga aagtactgga
     8461 acacgaaagt cgatcttctg ttaagttgac tctcacgtta catgacacag aaggaaaaat
     8521 agagaaagct ggtacagaat acgtttttgg cccactggat tatcaaattt cagaaggttt
     8581 ctatcctaca ttgatggatt taatccgcct tgatgtgttt aaagaaacgg atgaaactat
     8641 gagtgtggaa gagtcttatc gaaacgaaaa acttttacaa gttttagaag aagagttaga
     8701 gagcgaccaa agaaaagtga atcaagggag tgaagtcgaa gtaaatgaag aagtaccatg
     8761 ggaacgacca atatttccaa agaaggagtc aaaagaaaaa gagacagtct atgttgacga
     8821 acaagctgat attccgactc agaaatcgat atttgaggaa gagaacgatg tgatgggtca
     8881 attggaggta gatccctttg aagaaacaat ggaggatgaa gagacggccg aagtagaagt
     8941 tgatccagtt gaagcgaatg aagagtcaac atggactgaa ggggattctc aggaatatat
     9001 tgaaccactt atcagtgaag aagtagaaaa aaacgaaata gagatacaaa aggcaactgt
     9061 atttgattat attttggatc aatatccgcc agagcatgaa tggatgaaag aaaaaaacaa
     9121 attattttta aatgagcttt attcgaaata tcaattaccc caaacctatc aagcattttt
     9181 agagagtaaa gaagaattaa tctcacaggg taaaggcaca cttttagaac agttagagtc
     9241 tgtccaatca acaaattggc atgagcttgc acaagaagat ttattagcca cctttgaaga
     9301 acgtcaacaa gaaacagatc aagaaattaa tgagtatgcg acggaacagt cgtctaattg
     9361 ggagaaagca aaagaggaac taaataaaga agaacagcga gtgattgaag aagaagtaca
     9421 aaaaattaaa gagcgatacg aaaagaaacg cgacaatgcg tattccttgt gtgtagcaaa
     9481 gatcaataat tttactcaga cgaatcaaga agcgttatcg aaagaaaaag aaaacttgtt
     9541 aaaagaacgt attaaagaac gaaaagaaga attttaccga ggtttgcgta cagataagct
     9601 aaagattagc aaagaattaa atgaacaact gaataagcta tatcaaacaa cgactgaagt
     9661 tcttatggaa aaatacgaaa agatccagca agaattacaa gtgcaaattc caaaatggaa
     9721 aaaagagtat gaaattcaac aacaagaatt gaaagaacaa gaagaaaaac aacggcaaaa
     9781 agaaaaagag cgcgaacaat tagaactaaa aaaacgtgaa caggatcttg cggaacaaca
     9841 aatggcaata gaaaaacaac ggttaaacca agaaaaggaa aaagaagcag ctgctcgtaa
     9901 ggaacgtcaa gaacaaatgg atacattgcg acaagctcag ttaaattatc tagcacaacc
     9961 tcaaccaacg ccttcagtag ctgctgttca aaccccaatg aacaaccaaa caaatctaac
    10021 tccttcacca cagcgttcct ttaacggatg gatggtggga tgtattgcaa gtttaagctt
    10081 gcttctaggt ggaggaacag tatttgcttt taatcatatc aatcaatctt cacaggctga
    10141 ttctgtggcc acaacgacgt caatcaagga agaagcccaa gaacaagcaa gaaaagagta
    10201 tgaacaacaa ttagaagaat tattgaatcg taccaatcag tcaacaacag aatcaagtat
    10261 ggaaaatagc aaagagagtg atcctagtaa ggctaaagaa ggatcaagcg attcaactgt
    10321 acaatcaaac acttccgaaa gttcagaatc aaatgaggtg aaataatgcg tgttagagaa
    10381 acaacgagac gaaaagacaa acgattcaat ttagaaaaga ataggtatct ttctcatttc
    10441 tatcgctata ctccttcagg agaagagcta ccagaaaaac atgacaaacg tatttctcaa
    10501 aagatttttt atagtggctt agcttatctt cctttaaact atgttgttac aagaatacca
    10561 gaagcatttc atcgatttga gattattcca ggaagtttac aaggagtgaa tatttttcag
    10621 ttacaagaaa tgccgcagtt attccatttt gattcaactg gtttttggaa tcctttgacc
    10681 ccaacaacaa gtttaggcac acgtttagtt gtttctacga tttgtgttgt tccagctgta
    10741 cttatgggat tgaaaatgga catgtggttt cgtcctctag cagatgggca aaaaggagat
    10801 aaccgattaa aaacgttaaa ggaaatccaa caaatttatc cgcaaatacc agaatcaaag
    10861 ggaggttttc ctggttatgg cggaatacca attactcatt ataaaaagta ctggtatatt
    10921 cagacggata cagtaaatac ttgtattgtt ggtacttccc gttcagggaa aggacagata
    10981 gaagttttag caaccattga caatttgtct cgtgcagaaa gacaaagttc aatggttgtt
    11041 aatgatccaa aaacagaatt atatgttgct agtaaagatg aactagaagc tagagggtat
    11101 gatgtgtatg catttaatat caccgatcca ctgcaatcaa tgagtgataa tccattggca
    11161 ctcatcgtga aatactggaa gcgaggagac atagacacag cgacacagtt aaccaatact
    11221 ttcacgaata cgatttatta tgatgccaac gcttcagaca ataaatactt taacgaaaat
    11281 gcgcaaaaag ctgtcaatgc gcttattttt gcgttattgg aacaagcgga tcagacaggg
    11341 gattactcca aattaacacc gaataatctc gtcgaacttc tttctgagat tggtggtttt
    11401 aattaccaag atcctgataa tgaattcaag cagctcaatg ctttagatga atttatgaat
    11461 cagttaccac ctggaaacat agcaaaaaaa caatatgggg caacaaaaat tggttctgat
    11521 aaagcgaaag gcaacattct atcgacagcg atcacaggac taaatccatt tacactgacg
    11581 aaaattgcga aaatgacttc tcaatcaacc attgattata agtccattgg ttttccgaag
    11641 tatttggatc tcaaactaca cgagagtctg ttaaaccagc gaattgttgt agagttttat
    11701 catcaaggaa aaaaatttca tgaggaacgt gtcaaagtag gctatagagg tttttgtgaa
    11761 attaactttg attgtcattt agaacaggga gatcatgttt gcttaaaata cgatcatcga
    11821 ggaaaagaat atgttgcttg gtatgagttt tctcaaagag tattgaaaga cgaagaggga
    11881 aatattgttt atcgaaaaaa acgaggagaa acccatttgc cagaattaga aaaagaagcc
    11941 gttctaacat tagatgagga taaaagtaac ttattagtag agtctattcg gatgcactat
    12001 accgataaac caatggctat ttttatgctc acacctgatt atgatccatc taaccatatc
    12061 attgttagta tttttcttag tcagttgtat aaagaattat ctacgcaatg tgttaagact
    12121 aaaggagata aatgtcaccg taggattcat tttattttag atgaatttgg gaatatgcca
    12181 ccaatggata atatggaagg aatcatgaca gtcacagctg gtagaaacat gttgtgggat
    12241 ttgtttatcc aatcctatca gcaactttat gcgaagtatg gggaacaaaa cgcagcgatt
    12301 atcaaagaaa attgtcagac acatatttat attatgtcga cagacgataa taccatagaa
    12361 gaattttcca aaaaagtggg gaataagacg gttgaacaag agaacagtac catcaattca
    12421 ttaggtatga atactcatat caatcgcaat gttgattcag atcgcatctt aactcctgaa
    12481 agaatttcta cttttttaga aggtgaaacg attgtactcg ctcctttaaa acgacaagat
    12541 ttgaaaggtc ataaaatacg gccgtatcct atttttaatc atggggaaac gaatcttcct
    12601 tatgcttatc aatatattga agatttcaat ccatcgtggg atatcaatga tatagacata
    12661 cattgtacac atgcggactt ggatcttaag gctttacaaa ttgattacga ttattttcta
    12721 cctgatatct atgcacgtcg actttatcac aatatgcacg atcaaataga agaggaagct
    12781 aaagaaaaca tttttattaa aatcgttcaa tctttagaca actcaacggc acaaaagtta
    12841 cttattcaat tttatgaaga gaagcaaata gatcgtttgc aagaatacct tgaaaaattg
    12901 cgtcaaaatg aagaaattac agaggttata aggaaacgac ttttgctaga agctgaaaag
    12961 gcggtgaaag aatgatcatt ggaggaatat tttccggcat tgccgactgg tggtcaggct
    13021 tatttgggga tggggatgca gatcccaaaa ccgtaacgaa agtcttacaa gattatggta
    13081 attatctgca gtatcaagat gtattcagtt ggatttgtaa tactttttta tggggtttga
    13141 ttaaagggtt atataatctc aatactttac tagaaaaaac aatttatcaa agctttgatt
    13201 taaaagactt attgaacgcc gctggtgtta atgaactgtt tcaaagtttg attagtaagg
    13261 tattggctct tttttgtgtc gtcacattaa tttatttagg cttaaaattt tttatgagta
    13321 aacatccacc aaaaatcaaa aatatcttgg ttaatctatt tatggccatg attttgattt
    13381 ttggtggtag ttctttaatc gatgaagggc taaatattag taaaaacttt tacggagacg
    13441 tgactgcagc aaataaagca gataaaactg gttcacctgc ttttcaaatt attcaaaata
    13501 atgtgattga tgtgagtacg ttactagaaa atgatccgaa caaagtagaa cacataccaa
    13561 cagacaaaag aaatgctctc acggcgaaaa attttaaaac agcgaatatc aatgggatta
    13621 ttacacctga tcaagctaag aaaatgtctg aatcaagtga tattagtaca gtacaaaaag
    13681 atcggttaaa ggcattacag tatcgactag agttagacga taatgggaaa gaaatccctg
    13741 ttcaaattag tgatgaaggt ttagcaaaat atgtgtatac ttcaggctat cgccgataca
    13801 ttagtagtcc aggtattatt ttagctggtg aatcttcttt gtcggtagcc tatttattta
    13861 tcttgtttac gattgttact tgcattattg agctggtatt taaaaaattc tatttagtga
    13921 ttgccgcgtc aacggacttt gagacaggac aacggatgaa aagtgctata gaagatattt
    13981 ctcaatcctt cttgttattg gcatttacga ttttagaatt acgaatctat acattaatgc
    14041 tttcaggtat cggtgatttg catgcggcag gaaagatcaa tggattcttg tatgtcgttg
    14101 ctttgattgt actaaccatt gcgctattca aaggctctca atcagttacg aaaattttcg
    14161 gcgttgatac aagcctgaaa aacggcagta attctcttct tagcatgttt gccttaggaa
    14221 atattgcgaa aaatgtgggt agcggagcta aaaaccttgc aagtgctggt aagagtggtt
    14281 taagccattt aaatgatatt cgtaaaaatg gatttggcca tcgaaaagat gttacccctg
    14341 ataacgggga agaacaatca gacgataaag ctacaactgt acctaatagt aagaaaacag
    14401 tttccgaaat gttcgggaaa gcgaaaaatg gtgtttctaa agccgcagaa ggtcttggtt
    14461 acgtcaatga acgtgggtta aaaggaacag ctgaagatct tacagaaaaa gccaaagaca
    14521 ccttagaaga taaattagac ggcacgagag ctaaagaatt ggctgaagct gtgaagaatc
    14581 catccgaagc actagaaaaa caaaaagaaa aagcttcaga agtcaaagaa ggactaaaag
    14641 atgcgtatgg tgaaggacaa gtcaatgcag cagtgaaagc taatacaaca accgaaaaag
    14701 aaaatcaaga aggtatagtg attccttcag tcaaagatca ccaagaagcg ttgcactcta
    14761 atgaaaattc gattgaagag aaaaattcca tagaagaaag aaattcagaa gaaggaaaaa
    14821 atggacagtt accaaaaact gatccagaac aatatcgcta taaacctaac agtgaccttg
    14881 aaaatgagaa gcgaatttca gatttatcaa aagtaaatca agaagacaaa gcagaaaatg
    14941 agggacagtt accaaaaact gatccagaac aatatcggta tagatctgtt aactccgaaa
    15001 atgaaaaacg catttcagat ttaccaaaac gaaatcaaga agtacaaacg gatgaggatt
    15061 ccatcgttct gccaaatgat aatggaatcg aagttggaac tgaaaaatca acgaaaattg
    15121 gtttacctaa ggcacaaaat ttaccaatga aagatagtcg tttgaatcaa ttcaaggata
    15181 atgatcaaag ttttgttcat caatcacctg caggtactgt tcaaatgaaa ccaagtcgtt
    15241 tgcctgaaaa tggaaatctg acaactgttt cttacaattt atctgaaagt ggtgagacag
    15301 ggaatgcgtc cgttcaaaat gttgtgacaa gagaagctgc accaaaacct attcaaaacg
    15361 ttcatacagg ttacaagcca gcaaatgtgg catttactgc accaacaaaa ataaatgtga
    15421 caagagaaac aaaaaacagg aacaatgcat tgaaagaaca actattgagg gatatcaaac
    15481 aggatatcaa accataaaag gcctacaagt taggcctttt ttctatgtat gaaaaggaga
    15541 aatcatttat ggataaatat agtaacatga aaaaccctcc aagatttagt ggagaatgga
    15601 agtttttcgc ttttttcttt ttagatctat taacgcttgg tggctgcttt ttttgggcga
    15661 aaatggtcaa taatcttgtc cacttaccac tcttttttgc actcttgaat tatggcttat
    15721 ggattgcgat agcgttagtg attgtttggc gaccctataa taacccaggt caacgacaaa
    15781 tttttgcgat tatcgagtct attttttttg cggacaagaa ccattatcat gcgttagatc
    15841 ctaaccgaaa ttatcatggt acgtataagg aggatgaata aatgcgagtc aaaggacaaa
    15901 attcagttga aaggaaatcc attttgcagt ttggaaaacc agaagagcgc tctatcttgg
    15961 acttatttcc atataaatcc tgtacagaag agggagtctt aattactaga gaagatcatt
    16021 ttcaacgtta ttatcgtgta gtttctacag acgtggaagg attaaatgaa caagagaaac
    16081 tagaacgaat gaatcagttg accaccgtca tgcgtacgta tgtgccaaca attaagttag
    16141 ttagtttgac cacagagacg gatctaacgg aacaaatcgt gcaaaagcgg caattattag
    16201 ataaaaatcg tatggaacag tccttaggaa gaaatctaca acgattaaaa aaatatgaaa
    16261 agaaattagt cgaagaaatc caggaattga aacgagcaga acaagaacgt cctgacttaa
    16321 gcttcttttt cgtcattgaa ggaaagacaa tcaaggattt acaaaccaga aaccgtcagt
    16381 taatgcgatc tagtggcatt ttagg
//
LOCUS       DADLIO010000055        16376 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.057, whole genome shotgun sequence.
ACCESSION   DADLIO010000055 DADLIO010000000
VERSION     DADLIO010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16376
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.057"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            200..1474
                     /locus_tag="JOX41_002041"
     CDS             200..1474
                     /locus_tag="JOX41_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAY6449763.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSP
                     SYCEHCRSVRIIRNGSYTTRTQILKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQSRMNFLPTVL
                     CMDEFKSMKSVSGSMSFICVDGTTHQLFTILEDRRLYKLTQYFLHFPRKARLKVKYLV
                     MDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQIMNRFRTSHSENQKKYR
                     RLKRYWKLLLKDSTTWEPLKRHYHRLFKRPISQTEIVDELLSYNEELRTAYHFCQLLR
                     YYFVKRGTEGFQETLKTISSTLPQSFKKKFTIFHCYQSGISNAFKVSHSNGVTEGLNN
                     KIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
     gene            complement(1857..2585)
                     /locus_tag="JOX41_002042"
     CDS             complement(1857..2585)
                     /locus_tag="JOX41_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAY6449764.1"
                     /translation="MLRIAIVDDDCTIVEGIRHYLLKKVPDIIIDHCYTDGDEAFKNL
                     QNQRFDLLITDITMGKISGLELIESLQQTSNRYFTSIVISAHQNFQYAKKGIDLSIKS
                     YITKPIDFPYLVKLVQEEKMRKSAANQNSLTDDSFNESIQQVIDYVQNNYSEKLTLKD
                     VATQFHYHPAYLGRAFKKETGYSFHDYLLDFRIKRASALLKDTFLSIDEISQKVGIDH
                     VSYFSVLFKKTTGHSPSNYRKKLL"
     gene            complement(2563..4137)
                     /locus_tag="JOX41_002043"
     CDS             complement(2563..4137)
                     /locus_tag="JOX41_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAY6449765.1"
                     /translation="MKNDLSKVIMRFTYILIFFITLLACFTLFFSYINVIEKEKNQNL
                     QNIQQITHYMETYNRILSGIVTEIYQNYDFQENLNDYYLSSPAEYMEDILSKDRSPTY
                     LVDNLKKLVQDDEVKNISISLDYEKYLSAYAPTKNEKISFIRSLSFISEDMPDATLIL
                     DVSINALKKSLFPTHYNYSLSNGIDSVNLSEDISPSKWKKTQQIAIGNHTLQVYENPN
                     YSSQTLLGLAIMIFLLMSLFILAIHQLLNRSFRNYIQQYQEIITSLNHSSTGDYKSIN
                     IENKVGDLKEIAMHINQFYLDNATYQKTLYENNWLKQEAKYAALQYQIEPHFLFNNLE
                     FIRMTAILNDDEEISDSIYLLSKLYRNNTYQPDIIDLKEELINIDLSLQLHQRRYRHN
                     FDYQLIDHIDQLMLPKLSLQPFVENYIKHGFDSSKKENRLTVYATETTNHYVLKIVEN
                     GKGMDQDKLEHIQQKLNDDIPYSENIGISNSFRRIKHLYPGDTRFVIESQLHVGTTIT
                     IKIQKGGNMHVENCNC"
     gene            4366..5304
                     /locus_tag="JOX41_002044"
     CDS             4366..5304
                     /locus_tag="JOX41_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAY6449766.1"
                     /translation="MKLKKGLLGNLKKNRALFIMLLPGALWLFIFCYIPMFGVVIAFK
                     DFRISSRGFFTSLFNSPWVGWENFKYLFASQDAWIITRNTVVYNVVGILLSTFCTVSL
                     AIILSQMANKRLLKKMQTFMIFPNFLSWVVISYFVYAFLSTDKGLINILLSNFGVEPI
                     NWYSEPKYWPFIIVFTSLWKGVGYGSIIYYASIMGIDTSYYEAALVDGASKWQQIRNV
                     VLPHLRSIIVIMLILSVGSIFRADFGLFYQLPRNSGALYDVTNVLDTYVYRGLMNSGD
                     IGMSTAAGLYQSSVGFVLILITNKIVNKLDPSSALF"
     gene            5316..6227
                     /locus_tag="JOX41_002045"
     CDS             5316..6227
                     /locus_tag="JOX41_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAY6449767.1"
                     /translation="MISKLKRQMYFSLPVERFFTILLILFTLSCIFPFIFVIVISLTD
                     EKALQLNGYELLPAQWSTDAYQYLIQDGGQLLRSLGVTIMITVIGTLITVFMTGTYAY
                     VLSRASFPYRKFFTFYLFFTMLFAGGMVPSYLVMTKMLGLKNTIWALILPLAFSPYNV
                     IILRTFFKKSIPESIIESAKMDGCSEFRVFFQIVLPLAIPGVATIGLFSSLGYWNDWF
                     NALLYIDTNKLIPLQYLLMKIQNSMEFLANNNDITLAQQQAIQNSLPQESTRMAMVVV
                     ATLPIAIVYPFFQKYFVQGLTIGGVKE"
     gene            6251..7723
                     /locus_tag="JOX41_002046"
     CDS             6251..7723
                     /locus_tag="JOX41_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAY6449768.1"
                     /translation="MKKNMQKYLIGGASVLTLGLLGACGSSNGEANNETGTTKVTWYQ
                     VGEEPKDFDEVMTKVNEKLKEEINVELDMRLIPDGDYQQKLGVMINSGEEYDICFVNG
                     TDYVNYGNKGAFISLNDHLDKELKDYAAELNEGFIEGGAINGETYGLPVNNDIATTEY
                     WTFNKDLVDQYQLDVENVEGVETLAPVLEKFAEKNTDTNITPIGMTRTSVCIPYDNII
                     GGGVPLAVAFEGDTQTVVNTYETPEMMTYLKAMHEFYKKGYILKDAATVTTDPFRIDS
                     KNWFLGRNSSGYQPLAQKKLEALAGHGLILKPAGKAFKTTGFARVAMHAVSASSKHPE
                     AALKLLNYVNTNQEVADLMVYGIEGKHYDRNEDGSITLTNSDDYYQGAWALVNTYLVS
                     KTSPITEESKKLEEESKKFQNEAPMSPILGFSFDASDFRTEIASVQNIVSQYEVLLSS
                     GTVDPEQYVPELLEKLEKAGLDKIQASAQEQYDEWRKSNK"
     gene            7774..8385
                     /locus_tag="JOX41_002047"
     CDS             7774..8385
                     /locus_tag="JOX41_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAY6449769.1"
                     /translation="MNENKWTKGFNWVFQLLLLNFTYFILICLGFGILGFFPATIALI
                     AGVVNRKKYGLQESVKFMSKIYKKNFVRYNLYCWSATLLLAGNITTIWLCWQQSAPLF
                     YLLSTLLSVITLFLVFAMLNWVVIKSLGLWMMGDRLIDYLLFTATMLPTVVMQGLVLG
                     IYFRILMILPVIFLFGGTAVTVILISKLTERALAKLPCQIQSH"
     gene            8415..10328
                     /locus_tag="JOX41_002048"
     CDS             8415..10328
                     /locus_tag="JOX41_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HAY6449770.1"
                     /translation="MKLTDKQVANIAFIQQLEIPLTQKDEEQIDLIFTDTKANVRQIK
                     ITKNEQQRICLSYSHEDLLYRGLFICLPRFLAQGGEMPYIEETSIIETSYSLDASRNG
                     VMNKETLKKFISYLALMGYNTLYIYTEDTYEVEDLPYFGYLRGAYTKEEVNEIVEFAS
                     GFGIEVVPSIQTLAHLTQFLKWYAQQELMDDQNTLLIGEEKVYAAIEKMIIACKEMYQ
                     TERIHLGMDEAYQAGLGRYLSLYGYCDRTTLMIQHMDRVLSIVDKYKMKPMIWSDFIY
                     KLLDETGKDRYYNPDFKLKALAAKGLPAGLTYVHWDYGSDEVSSYEKVIDNHLKFCDI
                     DHYVLASGAHIWGRLAPNHGKTEAIVSAAVKASKNKGVRSVMLTTWGDEGQETEHWHS
                     LIGALKLADYVYSEEEWNDFEEIYDRLLGTGSYQLMSELRYFDEVDTITNNNLQMASV
                     SKLLLWQDPLVGIYDFHVAAHNKIATRTIGTYYHELAQKLDMNKNWNPKQPILTTIRQ
                     RYILLAEILAQKAELGIYLQHCCLVEDLAGLMELANRCEALANRVNELASIHEIIWYQ
                     TYKTYGWEVLEQRYAALAHRLKTVARRIKNHLQGQDALEELLEERLPFCQYQVPLEIS
                     GFNYRQSSVSGYN"
     gene            10456..13437
                     /locus_tag="JOX41_002049"
     CDS             10456..13437
                     /locus_tag="JOX41_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 42"
                     /protein_id="HAY6449771.1"
                     /translation="MLSDYYQNLSVISVNTEPLRNYYIPYASKEEAKQELEREKTSQF
                     IDLNGTWDFQYYPSVQQLPENFFQEAFTESYDRISVPGVWQTEGFDLPQYINVSYPIP
                     FDPPYVPNDTPCGVYRRQFQIEQTDARFYLNLEGADSNCFVWINRNFVGYDQVSHSTS
                     EFDVTKYLQVGVNEIQILVMKWCDGTYFEDQDKWRMSGLFRPVYLLQRPTMHLTSYQL
                     RTLTDPKKGSGTLMVSFQRFTPIEVSLPISYELFHPDGRLIAKGECYSEQQINLDVED
                     CLFWTAETPKLYTLLLTCNGEYFKEKVGFRALTIKNRKLLLNGTPIKLYGVNYHDVNQ
                     QGTPVMTREQLRADLLLMKKLNVNTVRTAHYPKSPDFYELADEIGLYVINEADLECHG
                     VVNLYDTEANYQLIANDPTFEKPIMDRVIRSILPYQNRSSIIMWSMGNESGYGVNFEK
                     AQALARKLDDSRLIHNERSIEPVIDQVNDFSNLDVISQMYPPLEDVHRHCQRSDTEKP
                     FFMCEYSHAMGNGPGDLKTYFDLIQQYDSFLGGCVWEWTDHAINRGTLETPSYLYGGD
                     FGEKYHDGNFCVDGLLTPDRQLTVGALEYRNIHSPIQLIAVDEELQEVTLSNITAFTA
                     GSAFNLSLEWYIDGKKTVYEVMNPFILEPGKSCSLPITVPTTIHGAHTVAVSLSVYKN
                     DELYGQQQLFLKKEKMRLPRTAHHNDAPQISVKGTELIIKGESFIYIYQLAKAAFTSV
                     KINQKELLERPTQFSIWRAPTDNDRNLVNKWKAAGYAEMSLEIRKKDWKFVDDHLLIE
                     TSYRGVIPGLQPIFTMHIQLKINGAGVINQKVSVEKNPIFPDFPRFGMDWPLNDTFSK
                     VSYCGYGPYESYPDKHYAAMFGIYEMEIEEFDQPYIKPQEYGNRWQCDWVSIKNHQGS
                     TMTVYGNSNFSALPYSQAQLTEKSHHYELIKENRTWFNLSYKQNGIGSHSCGPYLEDR
                     FRFMEDTFDWNIVITFKGENR"
     gene            13434..15095
                     /locus_tag="JOX41_002050"
     CDS             13434..15095
                     /locus_tag="JOX41_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HAY6449772.1"
                     /translation="MKETKINQVKKKLSRYQEVVYRNHCLKWSKNKLNVRFNGLFYRF
                     EQLEEVWKPVTNFQSCPVQLINDPKETYDLCITHLYNQHLKNDGFYLKVTNDNQLTIE
                     SANLRGFQYAMEALLESFFSVGDQLLLPELILKHEPSVKIRGIIEGFYGIPWTHEMRL
                     SLFSYMKDNQLNTFMYAPKDDELLRKKWRELYDAQELDKFKELLSAAEASNIDFWYLI
                     SPGNDIDITCEEDIQVLLKKLEQLIELGVFQFGLLMDDIDYQLKGAAKRRFREPAFAH
                     AYLVNRVEEYLSTRLSNHELVICPTEYDNRHGSRYLATLSQEIPEQLPFFWTGPSTLA
                     ASISTEELQEMASVYQRPMLIWDNIPVNDYLEDKELLFMSPYENRTPNLSKERYQVTG
                     VVSNPMAQLEASKFTINSMANYLWNCERFDPLETWTSVVEKVVGSKLQPAYLTLTNAF
                     PNHYTSSLLSDEELLLAKDPEWVTKEMAALVQAVKWIQQEQHTSRLRTELEPWLQAIT
                     ESWTFWQEWQLKKDPKEAEEWLAKKKTHRIGRDLVTAHLEQIIKS"
     gene            15135..16067
                     /locus_tag="JOX41_002051"
     CDS             15135..16067
                     /locus_tag="JOX41_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HAY6449773.1"
                     /translation="MVKRLISANYSDVKKMTSKELKQSIKASEGRVIVCETVANTLPQ
                     SGEITNAEVASAFGADLILLNGFDCYRPAVFGLPNVTIEKVFDLQQTIENPIPKLKEL
                     VGRPVGINLEPIAPKTNMMSEKVEISQGRASSVETIQKAEELGVDFICFTGNPGTGVT
                     NLEITKSVKMAKKYFSGLIIAGKMHSAGSEEPVVNKEAIISYAEAGADILLVPSVGSI
                     PGFLEQDLIEAVRLAKKYDLLTMSAIGTSQESARPETLRQLAIMNKSCGVDLQHIGDA
                     GYGGLAPAENIFETSVAIRGMRHTINCVSRSINR"
BASE COUNT         5312 a         2649 c         3273 g         5142 t
ORIGIN      
        1 gctctttgtc aaataggact gatagagtga tataagaaca tctaaggtag aattgatttt
       61 gcttctataa tattttgtgt tggtggaaaa tcgaaggcga ttttctacta acactttttc
      121 ttcgtttcaa ctcaaaaaga gactcacttt tggtaaaatt tagtcgacca aaacgtcatc
      181 ctaccaaagg agtctctcaa tggataatca tactagaaaa ttactcggat taacagataa
      241 acatttattt tttgatgaag aatggctgat tgaaaaagaa tataaaggcg ttcaagcgca
      301 gtttattaaa ggaaaattgg atgactctcc ttcctattgt gaacactgtc gatcggttcg
      361 tattatccgc aacggttcct atacgacacg cactcagata ttgaaagtca aagaaaagtt
      421 aactatttta gaattaaaac gtacccgttt tctctgccat gattgtggaa ggaccttttc
      481 tgcgaaaacg gacttagttg atgaacatca tcaactaaca aaggaactga agcaggcaat
      541 tctcatggaa ctgtacgaaa atcaatcacg taaactaatc gctaagaagt acttcgtctc
      601 ggatgggacg gtgacacgga tcttgcgtga agcaacgaag cattaccagt cacgtatgaa
      661 cttccttccg acggtgttgt gtatggatga gttcaaatca atgaagtctg tttctggttc
      721 catgagtttt atttgtgttg atgggacaac ccatcagcta tttacgatcc ttgaagatcg
      781 cagactttac aaactaactc aatacttcct gcactttcct agaaaagccc gtttaaaggt
      841 caagtaccta gtgatggaca tgaatgccag ctattgtcag ttgcttaaaa cagtctttcc
      901 aaatgcggag atcgtaactg accgctttca tattgtccaa cacatcaatc gcagcttcaa
      961 tcaattacgt gtccagatca tgaatcgttt tcgaacctca cactctgaaa atcagaagaa
     1021 gtaccgtcgg ctcaagcgat attggaaact cttactcaaa gattccacga catgggagcc
     1081 actcaaacgg cattatcatc gactgtttaa acgaccaatt agtcaaacag aaatcgttga
     1141 tgagctgtta agctacaacg aagaattgcg aactgcgtat catttttgtc aattattacg
     1201 ctattatttc gttaaacgag gtacggaagg ctttcaagaa acccttaaaa caatttcatc
     1261 tacgttacct cagtcgttta aaaagaaatt cacgatcttc cattgctacc aatcgggtat
     1321 ttcaaatgcc tttaaggtgt cccactcaaa cggcgtcact gaggggctga ataacaagat
     1381 caagctgatt aaacgaattg cgtttggtta tcgcaacttt tataactttc gggcacggat
     1441 ctatttacaa caaggtctga tctttgaaaa ctaaaaaaat atgcggcgca cagaacgcgc
     1501 cgcatatcgg actaagtttt attcaaattt gtcttcacca acacgatttg acgaagagcc
     1561 tatttaaata actacatcca tttattctat cttctaaaat agcctttttc atttcagtta
     1621 aatagttcag cgccattttt gcactcgact tgcatagtag ttttttccat attcctcaac
     1681 ctcagcgggg gttgaagaca taaggaaaat cctatgcgtt atgctcaact ggatctgatt
     1741 aaatattcta atgtattttt ctctaccatc attaaatggt taatagccaa aaatcaccac
     1801 ttttcaatgg ctccttgttg tataagtata actagaagat gaacacgtct gagaaattat
     1861 agaagctttt tacggtaatt actggggctg tgtccagtag tttttttgaa gagaacagaa
     1921 aaatagctca cgtgatctat tcctactttt tgactaattt catcaataga taagaatgtg
     1981 tctttcagta gagcacttgc tcttttgatt cgaaagtcta gcaagtaatc atgaaaggaa
     2041 taacctgttt cttttttgaa ggcccgtcct aaataagcgg gatggtaatg gaattgtgta
     2101 gctacatctt tgagcgtaag cttttcacta taattgtttt gaacgtaatc aatcacttgt
     2161 tgaattgact cattaaaaga atcatcagtt agagagtttt gattagctgc tgatttacgc
     2221 attttttctt cttgtactaa cttaactaaa taaggaaaat caatgggttt cgttatgtaa
     2281 cttttaatag ataaatcaat cccctttttt gcatactgaa aattttggtg ggcactaatg
     2341 acaatactag taaagtagcg attggatgtt tgttgcaaag attcgattaa ttcgagtcca
     2401 gaaattttcc ccatcgtaat atctgtgata agtaaatcaa agcgctggtt ttgcaggttt
     2461 ttaaatgctt cgtctccgtc tgtgtagcag tgatcgataa tgatgtcggg gactttcttc
     2521 aaaagataat gccttatgcc ttctacaatt gtacaatcat cgtcaacaat tgcaattctc
     2581 aacatgcata ttcccccctt tttgtatttt gatagtaatc gttgttccga cgtgtagttg
     2641 gctttctata acaaaacgtg tatctccagg atagagatgc tttatacgtc gaaaagaatt
     2701 tgagatgccg atattctcac tataaggaat atcatcatta agtttttgtt gaatatgctc
     2761 cagcttgtct tggtccattc ctttcccatt ttcaacgatt tttaacacat aatggttggt
     2821 tgtttcagtt gcatagacag tcaaacgatt ttcctttttt gatgaatcga agccgtgttt
     2881 aatataattt tcaacaaatg gctgtaaaga aagttttggt aacattaatt gatcaatatg
     2941 atcaatcagc tgatagtcaa agttatgtcg ataacgacgt tgatgtagtt gcaaggagag
     3001 gtcgatatta attaattcct ctttcaaatc aattatgtcg ggctgatatg tattattgcg
     3061 atacaacttg ctcaataaat atatactgtc gctgatttct tcgtcatcat tcaatatggc
     3121 agtcattcga ataaattcca aattattaaa tagaaaatga ggctcgattt gatattgaag
     3181 tgctgcatac tttgcttctt gcttcaacca attattttca taaagtgttt tttgatatgt
     3241 agcattatct aaataaaact gattgatatg catagcgatt tctttcaaat caccgacttt
     3301 gttttcgata ttgattgact tgtagtctcc tgtagatgaa tgatttaagg aagtaatgat
     3361 ttcctgatac tgctggatat agttacgaaa acttctattt aataattgat gaatagcaag
     3421 aataaacaaa ctcattaata agaaaatcat gattgccaga cctaataagg tttgtgacga
     3481 ataatttgga ttttcatata cttgtaatgt gtggttaccg atagctatct gttgcgtttt
     3541 tttccattta gaaggcgaga tgtcttcaga taaattgacg gaatcaatac cattagacaa
     3601 agaataattg taatgtgttg gaaagagact cttttttagc gcgttgatcg aaacgtctag
     3661 aatcaatgta gcatcgggca tgtcctcact aatgaaactt aatgaacgaa taaaagaaat
     3721 tttttcgttt tttgtaggtg cgtaggcact taagtatttt tcgtaatcta atgagataga
     3781 tatattttta acttcatcat cttgcacaag tttttttaag ttatctacta aataggtagg
     3841 ggagcgatcc tttgacaaaa tatcttccat gtattcagca ggtgatgaga ggtagtagtc
     3901 attaaggttt tcttggaaat cataattttg atagatctct gtcacgatac cggagagaat
     3961 acgattatat gtttccatat agtgggtgat ttgctgaatg ttttgcaggt tttgattttt
     4021 ttctttttca atcacattga tataggaaaa gaacaatgtg aaacaggcaa gtaaagtaat
     4081 aaaaaaaatc aatatgtatg taaaacgcat aataactttt gataaatcgt ttttcattca
     4141 aagtcctcat tttgataatc tctaatttta tgaatcatta tagcacatat tacaagtgat
     4201 gtaaacgctt tgcaaacagg gctacttatg attgtgaata cagtttccgt ttaaaaacta
     4261 ttctattgta gaggtttaat aaactaaaaa taatgtataa aaaattaatg taagcgatta
     4321 accaagtggg tataatcaag gaaacgctga gagaggagag acaaaatgaa gctaaagaaa
     4381 gggttattag gaaatctaaa aaaaaaccga gcattgttta ttatgctttt accaggtgcg
     4441 ttatggttat ttatattttg ctatatacca atgtttggag ttgtaatcgc ttttaaagat
     4501 ttcagaattt catcaagggg attctttaca agtttgttca acagtccttg ggttggctgg
     4561 gaaaatttca aatatctctt tgcttcgcaa gatgcttgga tcattactcg caatacggtt
     4621 gtttataacg ttgtaggtat tttgctaagt actttttgta cagtgtcatt agcaatcatt
     4681 ctgagccaaa tggcgaacaa acggttattg aaaaagatgc agacatttat gatttttcct
     4741 aattttttat catgggtagt catcagttac tttgtttacg catttttgag tacggataaa
     4801 ggattaatta atattttact aagcaatttt ggtgtggaac ccataaattg gtatagtgaa
     4861 ccgaagtact ggccttttat tattgttttt acgagtttat ggaaaggcgt aggctatgga
     4921 tccatcattt attacgcgtc aattatgggg atcgatacta gttattatga agctgcttta
     4981 gttgatggtg ccagtaaatg gcaacagata aggaatgtag tcttgccaca tttaagatcg
     5041 attattgtca ttatgttgat tttgtctgtt ggtagtattt ttcgagctga ttttggattg
     5101 ttttatcaat tgccaagaaa ttcgggggct ctttatgatg tgacgaatgt attagatact
     5161 tatgtctacc gtggattaat gaatagcgga gatatcggaa tgtctacggc agcgggatta
     5221 tatcagtcat cagttggctt tgtcttgatt ttgattacta ataagatagt caacaagtta
     5281 gatcctagtt cagcactatt ttaggaggaa tcaaaatgat atcaaaatta aaacggcaga
     5341 tgtacttttc gctgccagtc gaacggtttt tcacaatatt actaatctta tttactctta
     5401 gctgtatttt tccctttatt ttcgtaatcg tcatttcatt aacagatgaa aaagcattac
     5461 aactcaacgg ttacgaatta ttgccggctc aatggagcac tgatgcatat caatacttaa
     5521 tacaagatgg cggacagtta cttcggtcat taggcgttac aattatgatt acagtgattg
     5581 gaacgttgat tactgttttt atgacgggaa cctatgctta tgttttatca agagcctctt
     5641 tcccttaccg gaagttcttt actttttatc ttttttttac catgttattt gcgggaggga
     5701 tggttccttc ttacttagtg atgacgaaga tgcttggctt aaaaaataca atttgggctt
     5761 tgattctacc tcttgctttt agcccataca atgtcattat tttaaggaca ttctttaaga
     5821 agtcgattcc agaatcgatt atcgaatccg ctaaaatgga tggctgtagt gagtttcgag
     5881 tttttttcca aatcgttttg cctttagcga tcccaggggt tgcaacaata ggtttatttt
     5941 caagcttagg ttattggaat gactggttca acgcattgct gtatattgac accaacaaat
     6001 tgattccatt gcaatatttg ttaatgaaga ttcaaaattc aatggaattc ttagcaaata
     6061 ataatgacat tacattagcg cagcaacaag caattcaaaa tagccttcct caagaatcaa
     6121 cacgaatggc aatggtcgta gtagctactt taccgattgc aattgtttat ccgttcttcc
     6181 aaaaatactt tgttcaagga ttgacgatcg gtggagtgaa agaataaaaa agaataggag
     6241 atgttaaaag atgaaaaaga acatgcagaa atatttgatt ggtggtgctt ctgtactaac
     6301 ccttggccta ttaggtgctt gtggtagcag taatggcgaa gcaaataatg aaacaggaac
     6361 cacaaaagtt acttggtatc aggttggaga agaacccaaa gattttgatg aggtcatgac
     6421 aaaagtcaac gaaaaattaa aggaagaaat caatgtagag ttggatatgc ggctgattcc
     6481 ggacggggat tatcagcaaa agcttggtgt gatgatcaat tcaggagaag aatatgatat
     6541 ttgtttcgtc aatggcacag attatgtgaa ttatgggaac aaaggtgctt tcattagtct
     6601 caacgatcat ttggataaag agttgaaaga ttatgcagct gaattgaatg aaggatttat
     6661 tgaaggtggg gcaattaatg gcgaaactta tggattgcca gtcaataacg atattgccac
     6721 aacggaatat tggaccttta ataaagattt ggtagatcaa taccaattgg atgtagagaa
     6781 tgttgaaggt gtagaaacat tggctccagt attagaaaag tttgcagaaa aaaatactga
     6841 tacgaatatt acgccaatcg gtatgacccg taccagtgtc tgtattcctt atgacaatat
     6901 tatcggtggt ggtgtaccgc tagcggttgc atttgaaggc gatacacaaa cagttgttaa
     6961 tacttatgag actccagaaa tgatgactta tttgaaggct atgcatgagt tttataaaaa
     7021 aggatatatt ttgaaagatg cagccactgt tacgacagat ccatttcgaa ttgatagtaa
     7081 aaactggttt ttaggtcgta actcaagtgg ttatcaacca ttagcacaaa aaaaattaga
     7141 agctctagcg ggacatggat taattttaaa accagctgga aaagctttta aaacgactgg
     7201 atttgcaaga gtggcaatgc atgcggtatc tgcttcaagt aaacatccgg aagcagcctt
     7261 gaaattgttg aattatgtga ataccaatca agaagtagcg gatttaatgg tttatggaat
     7321 tgaaggaaaa cactatgatc gcaatgaaga tggttcgatt actttaacaa actctgatga
     7381 ttattatcaa ggcgcttggg cattggtaaa tacttatcta gtttcaaaaa cttcaccgat
     7441 tacagaagaa agtaaaaaac tagaagaaga aagtaaaaag tttcaaaatg aagcaccgat
     7501 gtctcctatt ttaggtttct cttttgacgc ttctgatttt cgaacagaaa ttgcaagtgt
     7561 acaaaatatc gtgtcacaat atgaagtact tttaagctcg ggaacagttg accctgaaca
     7621 atatgtacca gagttgttag aaaaactaga aaaagctgga ttggataaaa ttcaggcatc
     7681 tgctcaagaa caatacgatg aatggcgaaa atctaacaaa taatttttta ctaaatgaaa
     7741 agaatagact aagcagttag tggggggatt caaatgaacg aaaacaaatg gaccaaagga
     7801 tttaattggg tttttcaatt gttgttacta aactttactt attttatact aatttgttta
     7861 ggatttggaa ttttaggttt tttccctgct acgatagctt tgattgctgg cgttgtgaat
     7921 cgaaaaaaat atggcttgca agagtctgtg aagttcatga gtaaaatcta taagaaaaat
     7981 tttgttagat ataatctata ttgctggtca gcaactttgt tgttggccgg caatattact
     8041 acgatctggc tttgttggca gcaaagcgca ccattgtttt atttattaag tacattatta
     8101 tcggtaatta cactgttcct agtctttgca atgttgaatt gggtcgtgat caaaagtctt
     8161 gggttgtgga tgatgggaga ccgactgatt gactatttgc ttttcacagc aacgatgttg
     8221 ccaacggtag tcatgcaagg cttggtgctt ggaatttatt tccgaatatt gatgattttg
     8281 cctgtgattt ttctgtttgg cggaacagct gtaacggtaa tattgattag taaattaact
     8341 gaaagagcgt tagcaaagtt gccttgtcag atacaatcgc actaattttt tcacaaaaag
     8401 gagtatttct ttctatgaag ttaactgata aacaagtagc taatatagcc tttatccagc
     8461 aacttgagat tccattgaca caaaaagatg aagaacaaat agacttgatt tttactgaca
     8521 caaaggctaa tgtgcgacaa atcaagatta ctaaaaatga gcagcaacga atttgcttgt
     8581 cttattcaca tgaagacttg ctgtatcgag gattgtttat ctgccttcca cgttttttag
     8641 ctcaaggagg agagatgcca tacattgaag aaacctcgat cattgagacc agttattcat
     8701 tagatgcttc tcgtaatggc gtgatgaata aagagactct aaaaaaattc atttcttact
     8761 tagcgttgat ggggtacaac acattgtata tttacacaga agatacctat gaagtagaag
     8821 accttccata ttttggttac cttcgcggag cgtatacaaa agaagaagtg aatgaaattg
     8881 ttgaatttgc ttctggtttt ggcatagaag tagttccatc gatccagacc cttgctcact
     8941 tgacccaatt tttgaagtgg tatgctcaac aagaactgat ggatgatcaa aatactctac
     9001 tgatcggtga agaaaaggtt tatgcggcaa tcgaaaagat gattattgcc tgcaaagaaa
     9061 tgtatcagac agagcgtatt catttgggaa tggatgaagc ctatcaagca ggtctgggac
     9121 gatatttaag cctgtatggg tattgtgatc ggacaacttt aatgattcaa catatggacc
     9181 gtgtgttatc aattgttgat aaatataaga tgaaaccaat gatttggagt gatttcattt
     9241 ataagctatt agatgaaacc ggtaaagata ggtattacaa tcctgatttt aaactcaaag
     9301 cattagcagc taaaggatta ccagcaggat taacctatgt tcattgggac tatggttcag
     9361 atgaagtttc ctcctatgag aaagtaattg ataaccattt gaaattttgt gacattgatc
     9421 attacgtttt agctagtggt gcccatatct gggggagact agccccgaat catgggaaaa
     9481 cagaagcaat tgtttctgca gctgtaaaag cttctaaaaa taaaggtgta cgttctgtga
     9541 tgttaactac ttggggagat gaagggcagg aaacagagca ttggcattcc ttaattgggg
     9601 cattaaaatt agcagattat gtctattctg aagaagagtg gaatgatttt gaggaaatct
     9661 acgatcgttt attaggaaca ggtagttatc aattaatgtc cgaattacga tatttcgatg
     9721 aagtggatac cattacaaat aacaacttac aaatggcttc cgtgagtaaa ctgctacttt
     9781 ggcaagatcc gttagttggt atatatgact ttcatgtagc cgctcataac aaaattgcca
     9841 ctagaacaat tggtacttat tatcatgagt tagctcagaa attagatatg aataaaaatt
     9901 ggaatccaaa acaaccaatt ttaacaacta ttcgtcaacg atatatactt ttagctgaaa
     9961 ttttagcaca aaaggcagaa ctaggcatct atttacaaca ctgctgtctg gtagaagacc
    10021 ttgcaggatt aatggaatta gcgaatcggt gtgaagcact agccaatcga gtaaatgaat
    10081 tggcatctat tcatgaaata atttggtatc aaacatacaa aacctatggt tgggaagtat
    10141 tagaacaacg atatgctgca ttagctcatc gtctgaaaac cgttgcgcgt cgtattaaaa
    10201 atcatcttca ggggcaagat gccctagagg agcttttgga agaacgatta ccgttttgtc
    10261 aatatcaagt gccgcttgaa atttctggct ttaattatcg gcaaagctcg gtgtcaggct
    10321 acaattaacg aaggaatctt cccgttgaac ggaccacttg ctcatctaat gggaaagtgg
    10381 ttcgttttct attcataagt agcttaccac taactctttt attaagaaga gaaaaaaagt
    10441 aggaagtgag aaaatatgtt atcggactat tatcaaaatc tgtcagttat aagtgtcaat
    10501 acagaaccat tacgtaatta ttatattcct tatgcaagta aagaagaagc aaaacaagag
    10561 ttagaaaggg aaaaaacgag ccagtttatc gatctcaatg gtacatggga ttttcagtat
    10621 tatccttctg tccaacagtt accggaaaat ttttttcaag aggcctttac tgaaagctat
    10681 gatagaattt ctgttcctgg agtttggcaa acagagggat ttgacttacc tcagtatatc
    10741 aatgtatctt atccaattcc ttttgatccg ccttatgtac ctaatgatac cccttgtggt
    10801 gtatatcggc gtcagtttca aattgagcaa acagatgcac gcttttactt aaatctagaa
    10861 ggagcagata gtaattgttt tgtttggata aatagaaact ttgtaggcta tgaccaagtg
    10921 agtcatagta catctgaatt tgatgtgacc aagtatttac aggttggggt taatgaaatt
    10981 caaattctag tgatgaagtg gtgtgatggt acctactttg aagatcagga taagtggcga
    11041 atgagcggtc tatttcgtcc agtgtatctt cttcaacgac caactatgca tctgacaagt
    11101 tatcaactac ggacgttgac tgatcctaaa aaaggaagcg gaacattaat ggtttctttt
    11161 caacgattta ctcctattga agtatcgtta cctatttctt acgaattatt ccatcctgat
    11221 ggacgtctca tagcgaaagg ggagtgttac tcggaacaac aaataaattt ggatgttgaa
    11281 gattgccttt tttggacagc agaaacgcct aaattatata cattactttt aacatgtaat
    11341 ggtgaatatt ttaaagaaaa agttggcttt cgagcactga cgatcaagaa tcgtaagtta
    11401 ttgctgaacg gaacacctat taaattatat ggagtcaact atcatgacgt gaatcagcaa
    11461 ggcacgccag tgatgacccg agagcagtta cgtgcagatt tgttattaat gaaaaaatta
    11521 aatgtgaata ctgtacgaac ggcacattac cctaaatcac cagattttta tgaattggcg
    11581 gatgagattg gtctgtatgt aatcaatgaa gcagatttgg agtgtcatgg tgtggttaat
    11641 ctatatgata ctgaagcgaa ttatcaacta attgctaatg atccgacatt cgaaaagccg
    11701 attatggacc gagtgatccg ttctattctt ccttatcaaa atcgaagctc tatcattatg
    11761 tggtctatgg ggaatgaatc tggttatgga gtaaattttg aaaaagctca agctttagca
    11821 cggaaattgg atgattcacg gttgattcat aatgaacgct cgattgaacc agttattgac
    11881 caagtgaatg attttagtaa cttggatgtt attagtcaaa tgtatccccc actggaagat
    11941 gttcatcgtc attgtcaaag aagtgatact gaaaaacctt tttttatgtg tgaatatagc
    12001 cacgctatgg gcaacggtcc tggagatctt aaaacgtact tcgatttgat tcaacagtat
    12061 gattcctttc ttggcggttg tgtctgggag tggactgatc atgcaatcaa tagaggaact
    12121 ttagaaacgc catcttattt atacggtggt gattttggtg aaaaatatca cgacggcaat
    12181 ttttgcgtag atggtttatt gaccccagat cggcaattaa cagtaggtgc attggagtac
    12241 cgtaatattc attcgcctat tcaactgatt gctgtagatg aggagctgca agaagtaacc
    12301 ttgagcaata taactgcttt tacagccggt tcagcattta acctttctct tgaatggtat
    12361 atagatggaa aaaaaacagt ttatgaagta atgaatcctt tcatacttga gcctggcaaa
    12421 agttgttcat tgcccatcac agtacctaca acgattcatg gtgctcatac ggttgctgtt
    12481 tcgctatctg tttataaaaa tgatgagctt tatggacagc aacagctctt tcttaaaaaa
    12541 gaaaaaatga gattgccaag aactgctcat cataatgatg caccacaaat ttcagtaaaa
    12601 ggcacagagc tgataatcaa aggagaatcc tttatttata tatatcaatt agcaaaagct
    12661 gcgttcactt ctgtaaagat caatcaaaag gaacttttgg aacgtcctac tcaattttca
    12721 atttggcgtg caccaacgga taatgatcgt aacttagtaa acaaatggaa agcagctgga
    12781 tatgctgaaa tgtctttaga aatcagaaaa aaagactgga aattcgtaga tgatcatctc
    12841 ctgatcgaaa cgtcttatcg aggagttatt ccaggattac agccaatttt tacaatgcac
    12901 atacagttga aaataaatgg tgcaggcgta atcaaccaaa aagtatcagt ggagaaaaat
    12961 ccgatttttc cagatttccc tcgctttggg atggactggc cgttgaatga tactttttcg
    13021 aaggtttctt attgtggcta tgggccgtat gaaagttatc ctgataagca ctatgctgcg
    13081 atgtttggta tttatgagat ggagattgag gaatttgatc agccatatat caaaccacaa
    13141 gaatatggta accgctggca atgtgattgg gtatcaatca aaaatcatca aggatctacc
    13201 atgacggttt atggaaactc taatttttct gctctgcctt atagtcaagc tcaattaacc
    13261 gaaaagtcac accattatga attaataaaa gaaaatagaa cttggttcaa tttaagttat
    13321 aaacaaaatg gtatcggctc acacagttgc ggtccttatt tagaagatcg tttccgtttt
    13381 atggaagata cttttgactg gaatatagtg attactttca aaggagaaaa tagatgaaag
    13441 aaacaaagat caatcaagtc aaaaaaaaat tatctcgtta tcaagaagtt gtttatcgaa
    13501 accattgctt aaaatggtca aaaaataagc tgaatgttcg ttttaatgga ttattttatc
    13561 gtttcgaaca gttagaagaa gtctggaaac cggtaacgaa tttccaatca tgtcctgtac
    13621 agctcataaa tgatccaaaa gaaacatacg atttatgtat aacacacctt tataaccagc
    13681 atttgaaaaa tgacggattt tatttaaagg ttactaatga caatcaactt acgattgaat
    13741 cagcaaacct tcgagggttt caatatgcta tggaagcctt attagagagt tttttttcgg
    13801 taggagatca attattatta ccggaattga ttctgaaaca tgaaccatca gtgaaaattc
    13861 gaggaatcat tgaagggttt tatggtatcc cctggacaca tgaaatgcgc ctctctcttt
    13921 tttcatatat gaaagataac caattgaata cttttatgta tgcccctaaa gatgatgaat
    13981 tattacgtaa aaaatggcgt gaactctacg atgcgcaaga attagacaaa tttaaggagc
    14041 ttttatctgc tgctgaggct agcaatatcg atttttggta cttaattagt cctggaaatg
    14101 atattgatat tacgtgtgaa gaagacattc aagttcttct gaaaaagtta gaacaactga
    14161 ttgagcttgg cgtatttcaa tttggtctat taatggatga tattgactat caattaaaag
    14221 gtgctgctaa acgccgtttt cgagagccag cattcgctca tgcctattta gtgaatcgag
    14281 tagaggaata tcttagcact cggttgtcca atcatgaatt agtcatttgt cctacagaat
    14341 atgataatcg tcatggttct cgctatttag caacgttaag tcaagaaata ccagaacaat
    14401 taccgttctt ttggactggc ccaagcacgt tagcggcgtc aatttctaca gaagagctgc
    14461 aggaaatggc ttctgtctat caacggccga tgctgatttg ggataatatt ccggtaaatg
    14521 attatttaga ggataaagaa ctattgttca tgagtccata tgagaatcga acaccgaatc
    14581 tttctaagga gagataccag gttacaggag tagtttcgaa tccaatggct caattagaag
    14641 cttcaaagtt tacgatcaat agtatggcta attacttatg gaactgtgag cgttttgatc
    14701 ctttggaaac ttggacgtca gtcgttgaaa aagtagttgg aagtaaacta caaccagctt
    14761 atcttacctt aaccaatgct tttccaaatc attacacaag cagtctgctt tcagatgaag
    14821 aattactgct agccaaagac ccagaatggg tcacaaaaga aatggctgct ttagtccaag
    14881 cagtaaaatg gatccagcaa gaacaacata catctagatt gagaacagaa ttggagcctt
    14941 ggttacaagc aatcacagaa agttggactt tctggcaaga atggcaatta aaaaaagatc
    15001 caaaagaagc agaagaatgg ttggctaaga aaaaaacaca ccgcatagga cgtgatttag
    15061 taactgccca tttagagcaa attatcaaaa gttagatatc ttaaaaaata aaaagcaaga
    15121 aaaaggagaa caaaatggtc aagagattaa ttagtgcaaa ctacagtgat gtcaagaaaa
    15181 tgacgtcaaa agagttgaag caatccatca aagcgagtga aggacgggtg attgtttgtg
    15241 aaacggttgc taatactctt ccacaatctg gagaaattac gaatgcagaa gttgcgtcag
    15301 catttggtgc agatttgatt cttttaaatg gtttcgattg ttatcgtcct gcagtttttg
    15361 gactaccaaa tgtgacgatt gagaaggttt ttgatctaca gcaaacgatt gaaaacccga
    15421 ttcctaaatt aaaagaacta gtcggtcgtc ctgtgggaat taatttagaa cccattgccc
    15481 ctaaaacaaa tatgatgagt gagaaagtag aaatcagcca aggaagagca agctctgttg
    15541 aaacgataca aaaagcagaa gaactaggag tcgattttat ttgctttacc ggtaatccag
    15601 gcactggagt aaccaattta gaaattacta aatccgtaaa aatggcaaaa aagtattttt
    15661 cgggattgat tattgctggg aaaatgcata gcgccggctc agaagagcca gttgtgaata
    15721 aagaggcgat tatttcttat gcggaagcag gcgcagatat tttactagtt ccttcagtag
    15781 ggtctatccc aggcttttta gagcaagacc taattgaagc ggttcggttg gcaaaaaaat
    15841 atgatttgtt aacgatgtct gcaatcggta ctagtcagga aagtgcccga ccagaaacat
    15901 tgcggcaatt agccattatg aataaaagtt gtggtgttga tttacaacat attggagatg
    15961 ctggatacgg gggattggca ccagcagaaa atattttcga aacctcggtt gcaattagag
    16021 gaatgcgaca taccatcaac tgcgttagcc gctcgatcaa tcgctaacaa aattaaataa
    16081 aaaatggtta aattgattat ttaagtggga acatacttga gatatcagct aacttctgtc
    16141 actttaaaaa agggactgtg acagaagtga aaatagacaa aaaatatccg aacaagagac
    16201 taggatagca gaaaaactat cgttttgcaa cgaggaccaa ctggaccgta ggagcaattc
    16261 tcttattgtt cggatatttc gcttgttcaa ggacttatgt ctgtagtgcc cttttttggt
    16321 aggaaaaatg gtagggaacc atatcatttt taatgaaaat caagcatttc aaaagt
//
LOCUS       DADLIO010000056        16276 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.058, whole genome shotgun sequence.
ACCESSION   DADLIO010000056 DADLIO010000000
VERSION     DADLIO010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16276
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.058"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(47..412)
                     /locus_tag="JOX41_002052"
     CDS             complement(47..412)
                     /locus_tag="JOX41_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449774.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            620..1102
                     /locus_tag="JOX41_002053"
     CDS             620..1102
                     /locus_tag="JOX41_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449775.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALTVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDSAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1299..2189
                     /gene="pstS"
                     /locus_tag="JOX41_002054"
     CDS             1299..2189
                     /gene="pstS"
                     /locus_tag="JOX41_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HAY6449776.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            2514..4985
                     /locus_tag="JOX41_002055"
     CDS             2514..4985
                     /locus_tag="JOX41_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAY6449777.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGHQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKVIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(5088..6824)
                     /locus_tag="JOX41_002056"
     CDS             complement(5088..6824)
                     /locus_tag="JOX41_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HAY6449778.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(6821..7525)
                     /locus_tag="JOX41_002057"
     CDS             complement(6821..7525)
                     /locus_tag="JOX41_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAY6449779.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            7656..8159
                     /locus_tag="JOX41_002058"
     CDS             7656..8159
                     /locus_tag="JOX41_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HAY6449780.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            8119..8457
                     /locus_tag="JOX41_002059"
     CDS             8119..8457
                     /locus_tag="JOX41_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HAY6449781.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            8478..9896
                     /gene="ffh"
                     /locus_tag="JOX41_002060"
     CDS             8478..9896
                     /gene="ffh"
                     /locus_tag="JOX41_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HAY6449782.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            10008..10586
                     /locus_tag="JOX41_002061"
     CDS             10008..10586
                     /locus_tag="JOX41_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HAY6449783.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            10590..11111
                     /locus_tag="JOX41_002062"
     CDS             10590..11111
                     /locus_tag="JOX41_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAY6449784.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(11190..11744)
                     /locus_tag="JOX41_002063"
     CDS             complement(11190..11744)
                     /locus_tag="JOX41_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAY6449785.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            11997..12272
                     /gene="rpsP"
                     /locus_tag="JOX41_002064"
     CDS             11997..12272
                     /gene="rpsP"
                     /locus_tag="JOX41_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HAY6449786.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            12284..12535
                     /locus_tag="JOX41_002065"
     CDS             12284..12535
                     /locus_tag="JOX41_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HAY6449787.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            12660..13451
                     /locus_tag="JOX41_002066"
     CDS             12660..13451
                     /locus_tag="JOX41_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449788.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            13621..14142
                     /gene="rimM"
                     /locus_tag="JOX41_002067"
     CDS             13621..14142
                     /gene="rimM"
                     /locus_tag="JOX41_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HAY6449789.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            14132..14893
                     /gene="trmD"
                     /locus_tag="JOX41_002068"
     CDS             14132..14893
                     /gene="trmD"
                     /locus_tag="JOX41_002068"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HAY6449790.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            15029..15376
                     /gene="rplS"
                     /locus_tag="JOX41_002069"
     CDS             15029..15376
                     /gene="rplS"
                     /locus_tag="JOX41_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HAY6449791.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            complement(15508..16269)
                     /locus_tag="JOX41_002070"
     CDS             complement(15508..16269)
                     /locus_tag="JOX41_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAY6449792.1"
                     /translation="MIYKDDLSNKYVSVIKSKLNLLFSYAMKKGYVEKNPIDEVVIDY
                     KRESKTIKIKDKFLEDDEYNRLVDFTTSHNKRYSLLFQWLYLTGMRSGEAIALSKDDV
                     HITNNNASVVINGTMMYRERSIADMKKSDSTKTAAGMREIDLPKKAIAIYNELLELNP
                     NGQFLFQTTKGTPFQLTAINTYLRSHKADMKIDKKLSSHIFRHTHISKLAELGTPLYA
                     IQDRVGHENSDITEKIYLHVTKGVKEKLKEDIEKL"
BASE COUNT         5375 a         2926 c         3302 g         4673 t
ORIGIN      
        1 ataaaaagaa gaaagtagct tctctttgta catatatggt ttgtttttat ggatgccgag
       61 cttttttata agataaggct accgcccata acgacccaag gatttgtgga actaagtaaa
      121 tacctgcaag aagcaagatc agctgggtcg gttttaaagg atgatagaag taacgccatt
      181 cagtaaaatt ggcgcaaaat aaataggaag tgacagtaga tataatattg gcaatgaata
      241 aagatataat acgcctgttc ctttgaaaat aatatccagc aaaaagagat aaaaatatca
      301 atgtgatgaa cccgcttacg gaatgataac gaaaatcaag cagtaaggcg aaatgcacat
      361 aaggaacaaa agataaaagc aacggaaggt ttttccagca agtttttatc atctttcatc
      421 accacctaac aagtgttatt attttgttag ttttattgta aattgaatcc tgcaataatc
      481 aattactttt tcattatttc tagattaaat gaataaactc tcatgccatt atctctaaaa
      541 aaaaagtttt tccccctaat ttttttagat agaaaattgt atagtatgat gagagaaaaa
      601 gtagtttggg ggaacgttaa tgagaagaaa agcagtaatc gatcggcttt atttattttt
      661 ttggtttttt cctatcgttt tgctaccttt tacatgggta aatgctgttg tacaaggtgc
      721 ggagatatta ggcctgatcc aaggaagcgg atttgtggtt tctaggaatt ttccagcttt
      781 gactgttttc tatttagtga taagtgtagg tctcttatta ccaaaatctc tgatcaatca
      841 ctacaattgg cagctgcttt acttttcttg cttattagta tttacatcta tgttttcttt
      901 gctgcctcgc ttgattatcg gccctaatgg tttgagcgag agtggattga aggattcagc
      961 ttattcctcc atgtatttct tgacgatcaa accatggttc tatttagtaa ttgcctcatt
     1021 tattcttgca acattttttt acttctggac agaaatcagg ataaaaagtg aacgatctgt
     1081 atctataaaa aataactatt gatggtggat catcagtaaa aaagcatatg agctgcgtaa
     1141 aatgcatgtt tctcatatgc tttttttatt attatgtaaa gaatgcgaaa aacgtttaca
     1201 tgatttttac ataacttaac tatattttta cagcaaccat acgagggatt tacagtcgac
     1261 tgataaactt tagttgtaaa taagaaagga gcaataaaat gaaaaaagta ttgtttactc
     1321 taggtatgat gggaattctt ttagccggat gcggctcagg atcaggaaat acagatggct
     1381 ctgccacaca aaataattca agtgactcaa atgaacaagt aaaaatcgtt gcggtaggtt
     1441 cgacagcatt acagccgtta gtcgatgcag cacaagaaag ctttgtacaa gaaaatccaa
     1501 attatcaaat ctctgtacaa ggaggaggaa gcggaactgg tttgagccaa gtcgaagctg
     1561 gagcagttac tatcggaaac tctgatgtat ttgcagaaga aagagacgga gttgatgctt
     1621 caaaattagt ggatcataaa gtagcagtgg tcgggatggc gccaatcgtc aataaagata
     1681 cagatgtcaa agatatcacc aaacaggaat tgattgatat ctttacagga aaaatcacta
     1741 actggaagga agttggcggg aaagatcaaa aaatcaacgt cgtgaaccgt gcaaacggca
     1801 gcggtacccg cgcgacattc gaaaaatggg gactggatgg tgctacccct gtgcagtccc
     1861 aagaacaaga ttcatcagga acagttcggc agctggtaag tcaaacacca ggagcaatca
     1921 gctatttagc tttctcatat ctcgatgatt ccacacaagc actaagtatc gacggtgtag
     1981 aaccaaaaga agagaatgta gcagataaca gctggggaat ctggtcatat gaacatatgt
     2041 acacgaacgg aaaaccttcc cctgaagtcc aaaaattctt agactacatg atgacagaag
     2101 aaatccaaga aggacctgtc aaagaattgg gctatttacc aatcacaatg atggaagtag
     2161 aacgtgatca cgaaggaaat atcaaataac tagcagataa acatgccacg gtagtcgtta
     2221 ctattaagga aaaatcaact atgtttccca catatacatt tttcctttaa ttgtgaaaaa
     2281 tagttcctca tattttgccg ttttttgagc taataccgag ggtcagctga ttaaacaccg
     2341 tttattcgaa aaaaagagct acgacataga actgtcgtag ctcttttttt gctatatgac
     2401 aggaatgaaa ggtgtttgca agcttaatgt gaggaacact ttccatatct gttctatact
     2461 ggataggaga agtttggaaa tatccagaaa acgaaatcaa tcgaggtagc cacatgaaga
     2521 ataaatggat aaatcgaagt aaaaaaaaga aagtaacaca aagatcatca gataaagtca
     2581 tccgtctttt tccatcgtat aaagaaggat taacggcaga tcaagtcaag gaacgaatag
     2641 aaaaaggtgc agcaaataat tcagtcgatc ccacattcaa aacaaatcag caaatcgtat
     2701 tggaaaacat atttacgtat ttcaatttga tctttcttat cttagccatt ttgctttgtt
     2761 tagtagaatc ctataagaac ttgacttttt taccagttat catagccaat acaggaatcg
     2821 ccatttttca ggaaattcga tccaaaaaga tcttggacga actaaatgtt ttaaatacag
     2881 caaaagtcaa tgtcatacgg gacgggatag aacaaacaat agatatagaa gaccttgtaa
     2941 tagatgacat tgttatttta gagactggac atcaaattcc agcagatgca gaggtcgtgg
     3001 aaggaaaact gcaagttaat gaggctttat tgacaggcga agcagatgaa ataaccaaag
     3061 aaataggcga tccattaatg tccggcagtt tcattgtttc cggaaaagct tacgcccgat
     3121 tagacaaagt tggagcagat tcgtatattt cccagctgac agtcaaagcc aagacaatgg
     3181 gagaaggaga acagtcggag atgattgctt ctcttaatca attgatcaaa tggattggga
     3241 tcatcattat tcctatcggt atcctgcttt tttctcaaag ttactttttt aatggaaaca
     3301 cgatcaaaga aagtgtcgtt gcaatggaag cagcattgat cggtatgata cctgaaggac
     3361 tgtacttgct gacgacgatt gcattagcat taagtgcgac taaactagca aagcaaagag
     3421 ttcttttaca caatatgaaa agcattgaga cattggcaag ggtaaatgtc ctttgtgtag
     3481 ataaaacagg aacgatcaca gaaaataaaa tgtctgttca aaaagtgatc gtctctaaaa
     3541 aacaagaaat aatcagtcag tcagatcaat tggaagcatg cattgctgac tatgcaaaag
     3601 cgatggcagg agacaatgca acaatggaag ctgttaaagc atattttaca aaaaccactg
     3661 atcaatccta tcaccatgtt attccttttt cttctgtcca aaaattcagc agtgtagcgt
     3721 tggcagacaa ggtgtatgtt ttaggagcgc ccgaaatggt tttgcgcgat caattgccgg
     3781 aatatgcgga agagtttgtt tctttcgctg aaaaaggcta tcgcgtgttg gtctttggtg
     3841 tgtacgatgg gattcttgaa gaaccagtat tgacagaagc agtcacacca ttaggctata
     3901 ttctgattgc taatcctatc agaaaagaag caagagccac atttgattac ttcaaaaaac
     3961 agcaagtagc catcaaagtg atttctggag ataatccgct caccgtatcc aatgtagctg
     4021 tccaagcagg gatttcacat gctgatcagt acgttgatgc atctaaatta tcagaagaag
     4081 aatatgaagc agctgtcgaa aaatatacag tttttggacg cgtcaagcca gaacaaaaga
     4141 aaatcttcgt tcaattgata aagcgtaaca atacagtagc tatgacaggt gatggcgtga
     4201 atgatattct agccatgaaa gaagcagact gcagtatagc gatggcttcc ggaaatgaag
     4261 ccgccatgca ggcctcacaa gtggtcttac ttgattctga cttttcacgc atgccagaag
     4321 ttgttgcaga aggacggcgc gttgtgaaca atattgagcg atcagccagc ttgtttttag
     4381 tgaagaatat tttctccttt ttgctctcac tgttttcagt gatctttgct ctgacctatc
     4441 ctttagaacc atcacaaatc acattgatta gtttgtttac tatcggactt ccatctttct
     4501 tgcttgctct agaagaaaac aaaaagcgaa tcagagggaa attcatcatg aatgtgatgg
     4561 aaaaagctgt gccaggtgga ctaacagata tgatcgtagt cggtgcgttg gtgatctgcg
     4621 gggtgacttt gaatctaaat aaaacagatg tttctacagc atctaccatg cttttgattg
     4681 cagtagggtt cctcgttctc tataaaatct gttcaccgct gaataaattc agaagtcaga
     4741 tcattctttt ctgtgctagc ggtaactttt tttcggtcat ctttttgcat aagctgtttt
     4801 caatcaccgg tatctcagct gtatcacttt tgctgttgag cattctattt ttctcggcag
     4861 attcgatttt taggcatttg accacattgg tagaatattt gtttgaacgt aaaaatgaaa
     4921 aagagcaaaa gccgtttagt cgcgtagcta aaaaatttct atcgatattt aaacgagaaa
     4981 attgacgaaa agtatctcaa aaaagagtaa aaaagaacaa ccactcgtgt atctttcgaa
     5041 gcaggatgag tcatccaact ttaaaacgca cgagcagttg ctctttttta cattttcgga
     5101 atggtaacgg tgaaagtcga acctgttcca agatgactgt ctacagtaat cgtaccatta
     5161 aggagttgca cgtagtcttt tacaatcgct aaccctaatc cggtcccgcc tgaatgtcgg
     5221 cttcgcgcct tgtctacgcg gtaaaaacgc tcaaagatcc gttcctgatc ctcaatgtcg
     5281 atacctatac caaagtcttg gacagaaaac gatagatcat ctgttgcctg atagcggata
     5341 ataatctcgc tgtcgctttt tgaatattgg acagcatttt caatcagatt tttgataatt
     5401 ggataaagga tatctgtttt agtagtaaat ggttcgttct ttccaatcaa tcgaatcgtc
     5461 aaccgtttct tttcgatgat tggctgataa ttttgaacga tttgctggaa ataaggttct
     5521 gtataaattg tctggatctc gtaagaattc tcgccatctt ttgacagctg gatgatttcc
     5581 cgaatcagtt tatctaaccg gatcgcatct ttttgcatga tctcaagaaa agaagtcaga
     5641 gtttgcgggt catcttttgc accatccagt aaagtctcgg taaaaccaat cagtgaagtc
     5701 acaggagttt ttaattcgtg agagacgttg ccaacgaaat ccttttgtag cttttctaaa
     5761 cgtcgcactt tcgttaagtc atacgccacc cctagaatct gtccggtacc ttctgaatta
     5821 gtaaagtagc gcaaactcaa gtctaatgtc tgccgacctt ctgtaagggt gatctcctga
     5881 tggatcagcg gatgctcagg agtcacttga tgaatcagct gaatgagttt tggctcttga
     5941 atgacttctg tgtaccgctg ttcaggttga tagcttacca cgtttaaatg tagctgcatc
     6001 tttggattaa gcagtagtaa acgagaatca gcatcatcaa tcaggaatac gccaatcatc
     6061 agttcgttca gtaacgtata taattgctct tctgtggtag tacacgcccg atacatctta
     6121 ctcatttgtt cgctcaacgc attaatcgtc tgatacaatt cttcccattg atcgggtgtt
     6181 tgcatgatta cttccgcctg attaggattt tgcaccattt tttttagtac gggcagcacg
     6241 gttttcaatg gctggttttt ttgatagatc agataataga tcattcctgc aagaacaagg
     6301 aagaaagaca gaaagaagaa aaagacccaa cggcgaaaac tctcagttct cggtaaaaaa
     6361 ccgcttgtcg gttctgcgat acgtaaaatg gcttctaact ggccactttt tttgactggt
     6421 aatgcgacat ataaaagatc ctcattcaaa gtagtacttt tgcgcaaagc gctacctagg
     6481 ttcccaccat tcaatacggc tttgatttcg ggacgggagt ttcgctgttc attcaatgtt
     6541 tcattgtttg tgtcaaataa gatctttcca gtagcatcca ttaaagtaat ccgttcgttc
     6601 gactgatgga cgaattcttc caaagcagtt ttgttttgcg ctgcttggag gttttcgaca
     6661 tctaattgcc ggatcagcag ttgtgctttt tttgtcaggt agctttcttg ctgttccacg
     6721 atctgctgtt gaaaataatg ggaaatcaat tgccagccac caaaaaacaa actaactaaa
     6781 agaataagaa agaagagacg ttcataaatt tttttccatt tcatcgtttt ggttcctgaa
     6841 acttatagcc aaatcctcta atagtcacca agtactttgg atgttttgga tctcgctcga
     6901 ttttttctcg caaatgacta acgtgtacat ctacgattcg gctttgtcct gcgaagtcaa
     6961 aattccaaat gcggtctagc aatgtgtctc ggtcgatcac acggtctttt cgtttcatga
     7021 aataaacaag taattcaaat tctttcggtg ttagttcaat cagatggtcg tctacggtca
     7081 cttgataatt ggtcaaatca gcagtgattt gtccaatcga tagatattca ggctcagctt
     7141 catcttttga ttgcttacga ggttcaatcc gtctgaatat tgctttcata cgggctaata
     7201 cttcgcgagg actaaatggt ttggtcaaat agtcgtcagc acctatttct aggccaatga
     7261 tccgatccac ttggtcatct ttagccgtca gcatcaaaat cggtgtttca tttttttctt
     7321 gacgcagccg ctgagtgatc tccatgccat ccatcgttgg aagcatcaca tctaaaatga
     7381 tgaaatcaaa tgattgttct aatgctaatt ctaatccttc gcctccatct gtggcactgg
     7441 ttaccttgta gccttctttt tccaaattga acgtcaagag cgttacaata gaaggttcat
     7501 catcaacaac tagtattttt ttcattcaaa tctcctttaa ataggtttca ttctgtttat
     7561 attttagcat agaatcagta caaagggcta ttttacaaaa gaaataaatg gtataatagg
     7621 aaggcacttt gctgaataga aaggaagagc agtcaatgat tggaatcagt gcatgtttag
     7681 gcggtctggc ctgtcgctat gatggacaga aaaaagaagt accagaattg atggaactag
     7741 ttgaaactgg agaagctgtc atggtctgtc cagaagtgat cggcggatta ccaattccta
     7801 gagatcccgc tgaaatcatt ggtggaaatg gattcgatgt gtggaaagat caagcaaaag
     7861 tatggacgac aagcggcgaa gatgtaacgg aagcgtacaa aaatggcgcg atcaaagcct
     7921 atcaaaaatt gcaggaaaaa cacattgatc tagtcatcat gaaggaaaaa agcccttcat
     7981 gcggaaccca ttcgatttat gacggaagtt tttccggaat aaaaaaaaat ggtgccggag
     8041 tggctactgc ttattttatt cagcaaaaaa tgactgtgct ctctgatgaa gaatggctga
     8101 aaactagagg tgagcagaat ggaaatcgaa aagaccaatc gaatgaacgc gctctttgaa
     8161 ttttattcga ccttattgac agaaaaacaa atgaactaca tggaattata ttatgcagat
     8221 gatttttcat taggtgagat cgcggaagaa tacgaagtaa gccgacaagc agtatatgac
     8281 aatatcaagc ggacaagcaa gatcttggag gattatgaaa aaaaactcca tcttttttct
     8341 aattatattg ttcgagaaca ggtattggaa aatatgactg catatattac agataagtac
     8401 ccggaagata aaaaactact tgaatatgta cagcaaattc aagcaatcga agaataaata
     8461 aaaggaatga agaaaatatg gcatttgaaa gcttaactga acgtctccag caggcgatgg
     8521 gaaaaataag aaaaaaagga aaagtatcag aagctgacgt aaaagaaatg atgcgggaaa
     8581 tccgccttgc cttactagaa gccgatgtta acttgcaagt agtcaaagat tttactaagc
     8641 gcgtacgcga acgtgcggta ggggcagaag tgctggaaag tttatcacct gcacaacaaa
     8701 tcgtaaaaat cgttgatgaa gaattgacga tcacacttgg ttctgaaaca gcagagttaa
     8761 ataaatcacc aaaaatacca actgttatca tgatggctgg tcttcaaggg gcaggtaaaa
     8821 cgacctttac tggtaaatta gccaattatt taaagaaaaa tgaaaatgct cgtccgctcc
     8881 taatcgcagg ggacgtatat cgaccagctg cgatcgacca attgaaagta ttaggtcaac
     8941 agctagacgt tcctgtattt gatatgggaa ctgaagtcag cccggtagag atcgtccgtc
     9001 aagggatgga gttagcaaaa gaaaagaaaa acgactatgt attgatcgat acggcaggac
     9061 gtctgcatat cgatgaaaca ttgatggatg agttgaaaca aatcaaagaa ttgacgcaac
     9121 caaatgagat tttgcttgtt gtcgatgcca tgactggtca agatgccgtc aacgtagctg
     9181 atagcttcaa ccagcaatta ggtattacag gggtcgtcat cactaaactt gatggggata
     9241 ctcgaggcgg ggcagcacta tcgatccgct cagtgacagg cgcaccaatc aaattcatcg
     9301 gttctggtga aaaattgact gacttagaag tattccaccc agatcgtatg gctagccgta
     9361 tccttggtat gggggatatg ctgacattga ttgaaaaagc gcagcaagac tacgacgaga
     9421 aaaaagcgga agaacttgca cagaaaatgc gggaaaattc attcgatttc aatgacttta
     9481 ttgaacagct tgatcaagtg atgggtatgg gcccactgga agatctaatc aaaatgatcc
     9541 caggaatgaa tcaagtccct ggaatcgaaa acgtcaaggt agatccaaaa gatgttgaac
     9601 gcaaaaaagc gatggtttat tctatgacgc cagcagaaag agcaaatcct gatctgttga
     9661 acccaagccg tcgtcgccga attgctgccg gttctggaaa cagtgttgtt gaagtgaatc
     9721 gaatgatcaa acaattcaag gaatcaagaa aaatgatgca gcaaatgtcc aaaggggata
     9781 tgaacatccc aggtatggac caaatgtttg gttcaggcgt caaaggaaaa ctaggcaaaa
     9841 tggcgatgaa tcgaatgatc aagaaaaata agaagaaaaa gaaaaaacgg aaataagatg
     9901 aaaaaaacag cttcggtaca gactgaaaat gtctactgcc ggagcttttc tatcagcaat
     9961 ttttattctt tactaataca attactctaa acgaagaggt ggcacagatg agatgtccgt
    10021 ggagtgaaca aacagaaagt atgcggcaat atcatgatac tgtctggggt gttcctgaat
    10081 atgatgacca aaagctgttc cgaaaattga tgcttgatat taatcaagcc ggattgagct
    10141 ggcagacgat tttaaataaa agtgaagcat tcgatgaagc atatgatcga ttcgatatca
    10201 aaaaagtcgc aaattatgga gaaacaaaaa tcagtgaact aatggaaaac aaaggaatta
    10261 ttcgtaaccg aagaaaaatc gaagcagccg tccaaaacgc caaagcagtc ttgaaaattc
    10321 aagaagaaat cggcagtttt tcagagtatc tttggtcgtt ttctaatgga aaaatcgttg
    10381 attcttctta tcattcacaa gaagaagtcc caacaacaag tcctctttca gatgaattag
    10441 caaaagatct aaagaaaaga ggatttaaat ttatcggaag cacaacaatc tatgcttttt
    10501 tagaagctgt cgggatcatc aatgatcacc ttgacagttg tttccgcaaa gaagaggtcg
    10561 tacgtatcgg cagaaagggc gaataaagca tgcgaaaaat catattttat ggtgctataa
    10621 gtttagatgg ctatttggca acgaaaacgg atgatcttca atggcttttt gacactccaa
    10681 caggtaagca aactacttat gaagcttttt atgaaacaat cgatacgacc atcatgggca
    10741 gaaaaactta tcaggaagca aaaaaatatt tggagaccga agcaatttat ccagagaaaa
    10801 agaatttcgt tttttccacc cacgcacaat tacaattgcc agatgctgag gtcgtaaacg
    10861 aagatcctgt tgcttttcta aaaaatctac aaatgacaga aggaaaagat atctgggttg
    10921 tgggtggcgg tcgattgatc aaaccgctat tggaacatca aatgattgat gaatggtata
    10981 tccagattac ccctgtatta ttaggggacg ggattccttt attccaaaaa ggaacatatg
    11041 aagcgcgttt tgaaatgcta gacacgacac gattcggtga atttatcgaa ttgcattatg
    11101 tacgaaagta gaagtaaata aaataaaaaa ggcaactata tgcagaaatg tcctgtacat
    11161 agttgccttt tttattaccg ttatgctttt tactctgtta atttgttaga aaaatctaga
    11221 tacgcatcta aaatcgtttg gaagaaactt aatgttcctt caacgatatt accattttca
    11281 tcaattagat tcgcaacgtt tccgatatat gcttccggtt gctgcaaggt tggcacattc
    11341 aaaaagacaa gtgattggcg tagatggtgg tttgcgccaa agccgccgat cccacctggt
    11401 gatgcagtaa cgactaaacc tggtttatga tcccaaacac tgtgtccata aggtcttgag
    11461 cctacatcta aagcattttt caatactgct ggcacagaac ggttgtattc aggagtaacg
    11521 aaaacgacac cgtctagtcc cctcacttcc tcacgaaaac gagtccattc agcaggagcc
    11581 tgttctggag tttcgagatc ctcattgtaa aatggcagat catcgatttt tacaaataca
    11641 ctttcgtacc cttcaggaag caatttcgca aaagcttctg ctactttttt gttgtaagaa
    11701 tcttttctta aactaccaat aaaaaatcca attttttttg tcatacgatt tttcctcctt
    11761 caaactatct ataataatct tacaaaagat aagtaactgg agcaaataaa aacacttact
    11821 gacaaaagct acatagaaga tagattactt atttttaaca aaaaagaagt ctaaaatctt
    11881 ctattttcta aaaaaaatcg aatttaatca agctgtaaag aaaaaaagct ttacagggta
    11941 aaaaaaaact gttacactac atcttgtgaa taaaacaatg gaggtggaaa taaataatgg
    12001 cagttaaaat ccgtttaaaa cgtatgggtt ctaaaaagag tccgttttac cgtatcgtcg
    12061 tagctgattc acgttctcct cgtgatggac gtttcatcga aactgtaggt acttacaatc
    12121 ctttgaaaga ccctgcagaa gtagttttaa aagaagactt agttcttgac tggttatcaa
    12181 aaggtgcaca accttctgac actgtacgta acatcctttc aaaagaaggc gttatgcaaa
    12241 aacaccacga agctaaattc tcaaagaaat aaggtgaccg gatatgaaag atttaagcga
    12301 cttagtctta acaatcgttc gtccgctagt cacttatcct gatcaagtca agttagacgt
    12361 cgtagagtcg aaagactttt acgagtacaa tctaacagtg gctcctgaag atattggccg
    12421 tatcattgga aaacaagggc gtgttgctaa agcaatccgc acaatcgttt acggtgttcg
    12481 gatcaatgca ccgaaaaaag tgcgtttgaa tatcatcgat gataaggaaa agtaaataaa
    12541 cgtgctgtac tcgaattttc gagtgcagct tttttgtttt ttttattaat tgaagaaatg
    12601 attatttggc aaaacaagca agaaagcgta tccttatagg aggagggagt gaacagccaa
    12661 tgagaaagaa aatgttattt attccatttg ctctattgtt aagcgcttgt agttcggtta
    12721 ctcaagaatc agacaataca catctatcaa gcagtatatc tgaaactgtt accagtccag
    12781 aaaaaagtag taccaaaacg gcttccacca ctgaacaaac aatggctacc tcaaataatg
    12841 agaaaaagac tgctttagac cagttgaaag aacaacagcc aaatgttccc atgcctctag
    12901 atgtaccagt ctcttcaggc tatctcaata tcgcagcgac acatacaaag caaggttatt
    12961 ctattttata ttacagaaca gatcgtcccc tcgggttgaa tgctgacgaa ttgaatcaag
    13021 aaacgcctat tgcaacctat ctatatcaat atgggtttgc ttctagtcaa gaaacaatcc
    13081 aagttttgca gccatttgag atcgacacaa atggtcagca agtggactta ggttctcgaa
    13141 tcacagggta tcagcaaggt gcagcaggtt caagttttct tgaatggcaa gaaggaaact
    13201 ggcgtattcg aatccgtggg aataatatag aaggccaaga tcccttacta ttagctaaag
    13261 aaatcgtagc ttatttggaa gaaaacagtc taccagcacc tgaacaattt ggtaaaatta
    13321 ctgttgatat gggtgatacg acgaatcgag ccgtagaagt aagctggcaa gaaccgaaaa
    13381 atgcctatac gatcactcat caagatccta tgtctgcgtt gaagatggca gtttctatga
    13441 agaggttgtg aaatcagcgc gctgatctga gcccatcatt taactccaag tcacaggaag
    13501 taatcaaaaa tagcacgccg catttttgca taattttggc ttaatacctt aaaagaaaac
    13561 tagaattgcc tcttcacaca tgctaaaata aaacagacaa aaaagaaatg gggatataag
    13621 ttgactgaat acttgaatgt aggaaaaatc gtaaacacac aaggtatcaa aggcgaagtc
    13681 cgtgttatct caacaacgga tttcccagaa gaacgttaca aaaaaggaac ggtgctaaca
    13741 ctattccaag acggaaaagc acctgtggaa ttaacagtca aaagtcatcg caaacataaa
    13801 aattttgact tattgagttt tgaaggacat ccttctatca atgatgtgga aaaatatcgg
    13861 gatggcatat taaaagtgtc aaaagacaac tctgtagatc tagctgaaaa tgaattctat
    13921 taccatgaga tcatcggtct gcatgtatta gaagatggaa ctgagttagg taaagtaaaa
    13981 gaaatcttgt caccaggtgc caatgatgtt tgggtcgttc aacgtccgaa aaaagctgat
    14041 atattgcttc catatatcgc ttctgtcgtc aaagaagtcg atttagaagc tggagtggtc
    14101 cgtgtagaaa ttccagaagg actgattgac gatgaagatt gatgtattga ctttatttcc
    14161 aagaatgttt gaaggtccta tgggggaatc catcatcggt aaggctgtag ataaaggatt
    14221 attagatatc aatatctcta acttccgcga ttattcagat aacaaacatc agacagtaga
    14281 tgattatcca tacggcggtg gagcaggtat gctgctcaaa gtccagccca tctatgataa
    14341 catccaagcc attgaaaaag ctgcaccgga tgtcaaaaaa agagtaattc ttcttgaccc
    14401 agctggtaaa cgattcgatc agaaaatggc agaagaattt tcacaagaag aacacttagt
    14461 attcatttgt ggtcattatg agggatatga tgaacgtatc cgcacattag tgacagatga
    14521 agtttcctta ggagattatg tccttactgg gggagaatta ggtgcgatgg tcatgatcga
    14581 tgcaacagtt cggcttttgc cagatgtgtt agggaatcag acttcagctc aaacggattc
    14641 ttattcaacc ggtttattgg aacatcccca atatactcgc ccggcagaat ataaagggat
    14701 gaaagtacca gaagtattga caaatggaaa tcataaattg attgaagaat ggcaattaaa
    14761 agaatcacta agaaggacct atcaacgtcg gcctgatctt ttggaaacac ttgaatggac
    14821 acctcaaatg acgaaatttt tagaagaaat caagaaagaa gaacaagaaa aaacagcaga
    14881 tgaagccaag tgactttttc taaaatcttc tttacagtag gttgataata tgttagtatt
    14941 ttatggtgag tgcaaaagca cttaactatt acgatattcc gctgtgagaa aagctcataa
    15001 gaatatttgg aataaggaga agaaaaccat gaatccatta atcgaagaat taacaaaaga
    15061 acaattacgt tctgacatcc cagcgttccg ccctggtgac actgtgcgtg ttcacgcaaa
    15121 agttgttgaa ggtactcgtg aacgtatcca gttatttgaa ggtgttgtta tcaaacgccg
    15181 cggtgctgga atcagcgaaa cttatacagt acgtaaagtt tctaacggag tgggcgttga
    15241 acgtacattc ccattgcata caccacgtgt tgcaaaaatc gaagtagttc gctacggtaa
    15301 agtacgtcgt gcaaaattgt actacctacg tgcattacac ggaaaagctg ctcgtatcaa
    15361 agaaatccgt cgttaatcat cgttatcaga cagagaaaga acccttggta ttcaagggtt
    15421 ctttttttat tatctgtttt tttatattaa cgatttctat ttggtacatt tttgattaat
    15481 aaaaaggggc aaaaaagggg caacaagtta cagtttttct atatcttctt tcaatttttc
    15541 ttttactcct tttgtcacat gcaaataaat tttttcagtg atatcactat tttcgtgacc
    15601 aacgcgatcc tgaatggcat acagaggagt tcctagttcc gctaattttg aaatatgggt
    15661 atgtctaaaa atatgtgaac taagtttttt atcaatcttc atgtcagctt tatgacttct
    15721 caaataggtg ttaattgctg ttagttggaa aggagttcct ttcgttgttt gaaatagaaa
    15781 ttgaccattt ggatttaatt ctagaagctc attgtaaata gctatcgctt tttttggtaa
    15841 atcaatttct cgcattccgg cagctgtttt tgtagaatca gattttttca tatcagctat
    15901 tgaacgttct ctatacatca tcgtcccatt tataactact gatgcattat tattggtaat
    15961 gtgtacatca tctttactta atgcgattgc ttcaccagac ctcatcccag tcaaatatag
    16021 ccactggaaa aggagagaat atcttttatt gtgtgaagtt gtgaaatcta ctagtctatt
    16081 atattcatca tcttctaaaa atttatcttt aatttttatc gtttttgact ctcttttata
    16141 atcaataact acttcatcga taggattttt ttctacataa ccttttttca tagcatatga
    16201 aaaaagaaga ttcaatttgg atttaattac actgacgtac ttatttgaca agtcatcttt
    16261 atatatcatg tcttca
//
LOCUS       DADLIO010000057        15997 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.059, whole genome shotgun sequence.
ACCESSION   DADLIO010000057 DADLIO010000000
VERSION     DADLIO010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15997)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15997)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15997
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.059"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            226..894
                     /locus_tag="JOX41_002071"
     CDS             226..894
                     /locus_tag="JOX41_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HAY6449793.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(1094..1324)
                     /locus_tag="JOX41_002072"
     CDS             complement(1094..1324)
                     /locus_tag="JOX41_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449794.1"
                     /translation="MTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGE
                     AYEDYFMIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(1451..2833)
                     /locus_tag="JOX41_002073"
     CDS             complement(1451..2833)
                     /locus_tag="JOX41_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAY6449795.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            complement(2989..4176)
                     /locus_tag="JOX41_002074"
     CDS             complement(2989..4176)
                     /locus_tag="JOX41_002074"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HAY6449796.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            complement(4183..5214)
                     /locus_tag="JOX41_002075"
     CDS             complement(4183..5214)
                     /locus_tag="JOX41_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAY6449797.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            complement(5230..6684)
                     /locus_tag="JOX41_002076"
     CDS             complement(5230..6684)
                     /locus_tag="JOX41_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAY6449798.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVDPSH"
     gene            6859..7764
                     /locus_tag="JOX41_002077"
     CDS             6859..7764
                     /locus_tag="JOX41_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAY6449799.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            7855..8532
                     /locus_tag="JOX41_002078"
     CDS             7855..8532
                     /locus_tag="JOX41_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAY6449800.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            8813..9709
                     /locus_tag="JOX41_002079"
     CDS             8813..9709
                     /locus_tag="JOX41_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAY6449801.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(9764..11134)
                     /locus_tag="JOX41_002080"
     CDS             complement(9764..11134)
                     /locus_tag="JOX41_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAY6449802.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            11372..12118
                     /locus_tag="JOX41_002081"
     CDS             11372..12118
                     /locus_tag="JOX41_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAY6449803.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            12115..12954
                     /locus_tag="JOX41_002082"
     CDS             12115..12954
                     /locus_tag="JOX41_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAY6449804.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            12955..13905
                     /locus_tag="JOX41_002083"
     CDS             12955..13905
                     /locus_tag="JOX41_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HAY6449805.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            14046..14798
                     /locus_tag="JOX41_002084"
     CDS             14046..14798
                     /locus_tag="JOX41_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449806.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            14817..15968
                     /gene="queG"
                     /locus_tag="JOX41_002085"
     CDS             14817..15968
                     /gene="queG"
                     /locus_tag="JOX41_002085"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HAY6449807.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
BASE COUNT         5190 a         2997 c         3222 g         4588 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacggt tgtgtaaaaa tatcatttta gagcataaaa
       61 aaaaggagtg gatttctcca ctccaaaaaa gtctaacttt tgggggtcac tacagtgtca
      121 cagtcctttt tttagtaaaa ggatacattt cttccttgta tattccatgc gtgttcgtga
      181 gaaagcatat ataatttaat taacagatag ttagggggag aaaaaatgat tttttcaatt
      241 acaatgaaac tggtgttcgg gttgatcggt ttattattag tggtacgttt gcttgggaag
      301 aaatccatgt cagaaatcac accgtttgat ttagtctata cgcttgtttt aggtgggatc
      361 ttagaagaat caacctatga tgacaatgtc catgtagggc atgtcctatt tgccattgcg
      421 ctttgggcag taatgattta tggtatcgaa cgtatcgtcc aaaaaaatga aaaggtcaat
      481 cgttgggtca aaggcgagcc atctgttcta atcaaagacg gcgtcatcaa catgacagag
      541 ttgacaaata accatatcga gatggagcag ttgcgagcaa tcttaagaca gcaagaatgc
      601 ttttttcttg aaaatgccaa acatgttatc ctagagaatg ccggtcaaat gagtgtattg
      661 aaaaaatcag atgaagacaa agctttatcg atcctgcttg tagatgaagg gcaaattcag
      721 cataaagtgc ttcagtccaa tcaattgact gaagcatggc ttatggagaa cttgaagaaa
      781 gaaggctatg cagatgtaaa acagctgatt tatgttgaat ggtcagaaga aaaagggctc
      841 tacatactaa ataaagaaga cgtcatgcat gaatcttacc gaatagatgg atagatagac
      901 agaggttgtg aaatcagcgc cttggcttgt tactcaaaac taagcgactt tttcacaacc
      961 tctgatatct aatatacgtt gttccagaag ttgcttcttc gaaaaataag ccaaaattcc
     1021 acaaaaattt aagaagcaat tttcgaaaaa tcctttctta ttttttgaag ttgatcactt
     1081 ctgtcacaac ctctcatgtc acaaaccatt tttttgtttc ctttaactca atataccgta
     1141 cgtcttccca caatatcggc tgatggtcaa tcataaagta atcttcatag gcttcaccaa
     1201 tgaagtgccc ttcgacctca tccaagagtc ttccaaattc atcttttaaa ttgagctgaa
     1261 tgattactgc tttacgagat aaaaaggctt ctgtcagtat actatcgatt tcttgcaatg
     1321 tcatttgttg tttaggaaga ggctgtttgc gtgcttcttc ttcatttttt tgataccgtt
     1381 gactagttct tccatcgcaa aagcagtccc ccattttaat ccaaatggcc gatctcgata
     1441 ctcgttatag tcaatgaatt tttttgctgt ccgtctcatc ttttccacct tctaatccac
     1501 tcataccacc tgcatgcccg ccaacgagag aactacgtgc gatggcgcgt cctccttgca
     1561 agagactatg cgcatggatg attgattgaa agccgtattt ttttctaatc gtatcgacaa
     1621 caaaatcaac tttcgcttca tttatctgct tttcaggatc ttcaaaaagg ttaagctgta
     1681 aacctgtcgc gtatacgagg tcggaacagt tcacgcctac acgccgaata tcctggtagt
     1741 ggtaatgctg gtggaaaatg gtcaataaag catctgctag atctctgcta gcatttgtcg
     1801 cttcgatttt catttgctgg tgaaacccgg tcttgccatt tggatcaaga tagcctaaag
     1861 agtatcctac ccataagctg actacttgtg tttttgctgc agatcgtctc aagcgagtgc
     1921 cgacttggtc ggccatttct ttgataacga tctcgatttc ttctcgtctt gtataatctc
     1981 tatctaggat ttgactattt ccgatacttt ttgattttgg tgtatattct tgtcccaaaa
     2041 aacttcgatc gatgccccaa gcatgggcat aaagctgagt accgatgacc cctagcttgc
     2101 ttttcaagtg ataataatcc gcgtgagcta aatcataaac agaatgtata cccatttgtt
     2161 tcagacgttt tgctgttcgt ttgccgattc cccaaaagtc agtgatatct gagattttcc
     2221 ataacttttc tggtacatct tcataacgcc attcagcaaa catttgcttt ccgtcttttg
     2281 agccattgtc taaggctagt ttagcaagta gcgggttatc gccaattcct atagtcgtgt
     2341 agattccggt ctgctcaaac acatctttat ggatcagttt agccatgtcg tacgcatttg
     2401 ttttaccaaa gagtgccatg ctatttgtta catcaaggaa gctttcatcg acggaataga
     2461 catgatggtt cgcttcgtct gcatattttt tatagataga attgatttct ctgttctttt
     2521 ccatataata ggccatcctt ggggcaacaa tatataaatc acttggatag gggaagggaa
     2581 gatctctggc acggctgata ttggtgatgc cgtaagcttt ttttgctgca ggactggaag
     2641 ccaagattaa tccgctaccc cgtgtttctg tcgaatcgga cggataggac atgactacta
     2701 atttagttgt aaggggatca agatcctttt caacgcactc tacggaggcg taaaaagatt
     2761 tgcagtcaat acataaaata tctcttgaag gttctttttc ataaacaaat accggatttt
     2821 gattcgccca cataacaatc acctcttcaa cacaattaga acacacgttc tctttccgtg
     2881 tcaataaaaa acagcaattt tcaaatacga gcaaaaggct cacatttgga aattgctgag
     2941 aggttatttt tatctatttg tttttagctg agatcgttga tttttttatc aaacatgaac
     3001 agcttctgga tcgatctttg ttgtcccatt tccaatgtgt gcaacataaa attccggagc
     3061 atagccgaca actttcatgt attcatcata gacattgttt ttgaaggcag gtatattttc
     3121 ttctttgaca agagcaatcg cacagccacc aaatccagct cctgtcattc gtgcacctaa
     3181 gacaccttct tgtttttgag cagcatctac tagtgtatct aattcgatcc cagttacttc
     3241 ataatcatag cgaagagagt ggtgagaatc atttaacagt tgaccaaatg cttctaagtt
     3301 cccagcttct aattcagctt ttgccttcaa agtccgctga ttttcagaaa cggcatggcg
     3361 agctctgcgt atcaatgtat catcgccgat ttggtcaata gttgattcaa attcttcttc
     3421 atctaagtct cctaaagaag agataggcaa agttttttgc aaacgtgcca aggcttcttc
     3481 gcattcgcta cggcgttcat tgtattttga atctgccaat tcccgccgct tattcgtatt
     3541 catgatgacg attgcataac catctagttt cactggaacc atttcgtatt tcagcgtatt
     3601 tgtatctaat aagattgcat gatctagctc accgaagccg atggcaaact gatccatgat
     3661 acctgaattg acaccgatga attcattttc tactttttta cctgtttgga ctagttccaa
     3721 gcgatctgtt tttaaatcaa acagatcttc taatacaaca cctactaata attctaatga
     3781 agcgctactg gaaagtcctg caccattagg gattgttcct tccactaata actcaaaccc
     3841 atgatcgatt gagtgtccag cttcttttaa tttaaggacc attcctttta cgtaatttgc
     3901 ccagtttgct tttttatcat attctagctc atctaaagta aaactaatga caccgatatc
     3961 gtcaaagttt gtggaataaa ctaatatttt attatcgtct cgaggtgctg ctacaccttg
     4021 cgttccataa gtgatggaag cggggaagac atggcctcca ttgtaatctg tgtgttcacc
     4081 aatcaaattg atgcgtcctg gtgagaagta ttgtgtagtt tttttaggtc cgaatgtttc
     4141 ggcaaatttt gtgtttaagc ttcttttgat ttccatgatg agttattcct ttcttgtttt
     4201 gattttgaat tctgttactg tttcaaatac tgatccggct tttaaatgaa tcgaaccaaa
     4261 tgctgagaag cgctctgcac ctggagctgt ttgagtctca aatgtgatgc caccgtgatg
     4321 tgccagtttt cggttgcgca tttctggtgt ttctgtgccg aaatttgcag tgaaaataac
     4381 cacactagaa gcatctgtag caatatctac ttggattctt ttatcggggc tagtcaagcg
     4441 agcggcttct ttacccaagc cggtttcttt taagaaaaat ggatgatcga ttccgtcaac
     4501 aagatttttt tgatccaaat cactagcaaa aacggacgct aattttttag gtatttgaaa
     4561 atcgaaagca cttcctgcag cattttcttt tacccctata ggaatactat ctgttcgcaa
     4621 aggagcataa gcttcgctat tgagccaaag ctcatgttga tcgattgact gagaagcatc
     4681 tcccgtcaag ttgaagtaaa catgatttgt cggattgaat aaagtatctt ggtcactggt
     4741 gccgcgagag gtcactcgcc agatattatc ttttgtcaaa gtatagcgga tttccacatc
     4801 cattgtacct ggaaaaccat gttctccgtc gggacttgta gtagtaaaaa tgacagaagc
     4861 ttcattttcg ccattcaaaa tgacataaga ccattttttt aattcaaatc caggagcacc
     4921 accatgcaga ttatgtccag tttttggatc tgtggctaat tggtaagttt ttccattgag
     4981 agaaaagcgg ccattttcga ttctccctgc ggtgcgaccg atagaagcac cgatatacgg
     5041 atctttttcg atatattctt cagcggtgtc aaatcccaaa actaattctc gatcatttga
     5101 ttttaaactg acgattctag cacctaaatc agagatagaa agtgctagct tgtttttgtt
     5161 ctccaaggtt atcaagtgat aaccttggcc aaaatctttt tctgtaatct tcattttcaa
     5221 gatcctttct taatgggaag gatctactgc atcgtgaagt tcatcttcca ttgtatcagc
     5281 tggagccaat ttgttttcca atttctcaac gatttgtgca tgttttttct ctgtcaatgt
     5341 aatcttccaa gcaaaaataa tagcggagaa aatcatcaaa gcagcaggag catagaatgc
     5401 ataagctttg aaagtcgtta cgccatgagc agtgatatca gcagcagtag cattaccagt
     5461 catcccagaa gcgatagcga caaaccctac gatcccgtta gacaaagcac cagcgatttt
     5521 atctagtaaa gggcgaattg atagagtaac agcttcgtta cggataccat ttttccattg
     5581 accatattca acagagtctg tgatcgtcat caaagcggat aagaaaatca attgttgagg
     5641 gaagtagaac aatactagcc cgatgataac gattggcaaa cttgaacctg cgatcgtaaa
     5701 gaaaaagtaa gaagaaatca tcattgcgat ccctccaagg taaacgtagc gacgagagat
     5761 gacgcgtgta agcattggga atagtggaac agctactaaa ccaagtaagg cagcaactag
     5821 accaacgatc caaaattcag ttggttggcc aagtacatat ttgaagaagt agaataatac
     5881 ggcagttgtt gctgcattgg caatcgcata agcgatataa gcaagggcaa gccacatcaa
     5941 ctgatcattt tgagcaactg ctttgaacac atctttgatc ccagcttttt cattttgctg
     6001 acggatcgca gtatcgactt cttttgtgcc caaggcagtg ataatcgcag taccgcctga
     6061 aataacagca gcaatcacac cgaaccagaa ccagcctgaa gcgccttcaa tatgtttatg
     6121 agtaacaaga taggtaaaga aagtaacgat agggacaacg actagagtag taccatttgc
     6181 acctagagaa gagccgaaac gagcaaacgt agcaaatttt tcacgttcct ttgtttccgt
     6241 actcaaagct ggaatcattg accaaaaagc gatatcctta aatgaataaa aactatccaa
     6301 taagatgaaa acgattgcaa ataatatgat aaataaagtc gtattatgag tagctaagcc
     6361 aaagaaattg gtaaagattg ctaccaagag tacggaacta acaacgccgc cgataactaa
     6421 ccatggtttg aatttaccgt attttgtacg agtattatcg atgatgccac caatcaaagg
     6481 atcaaaaata atttcaacta agcggatacc tacaactaag cttgtaactg tagcaatcat
     6541 ttttgcattc gttgccttat ctgttcctgc gaacatctgg cttgtcacga ataccataaa
     6601 ataagtgctt aatgtaacat agaatgtgtc gtgtccaaaa gcgcctaaag cgtaggacac
     6661 acgttggatc attttgcttt tcataatctg tattcctctc ctgttcaata tataatacta
     6721 agtaaaccgg ttacaacgaa taacaaagat cttttaatga cttaaactta acaagaaatc
     6781 gcttcctttt taatatattt ctgtgacttt tatttaactt tttgttgcat tatactaaag
     6841 gagtaaggag ggatagacgt ggagcaatcg atttttttaa aaaaggaaca tcaacaagta
     6901 gaaaaagaat tgtattttga tttttgtggt ttctctaaaa cgatgccgtt tcattctttt
     6961 ggtcctgcta ttcgcaatga ttacatcctg catgtcgtga tggaaggcaa aggatcttat
     7021 catgtgaaaa atcaacaatt ccaattgaaa aaaggtgatc tgttcttgat tcgtccagga
     7081 gactcgacgt tttacttatc agatggagaa gatccgtgga tgtattgctg gctttcattt
     7141 ggtgggagtg ctgcagaaga aatcattcgg cagtcgcttt tcagagaaga ccaatacacg
     7201 atggtctctt ctgacataca aaaatatatc gacattattt tagaatgcat gaaagatacg
     7261 gaagaaacct tggaaaatga attacagtta acagcattaa cctaccgttt tttatcagtc
     7321 cttttaaaag atggcggaaa ggtcagcggt ggtgtacaaa aggttcattc ctctttagct
     7381 gttgaaacag tcaaatacat cgaggcacat tatgctgaaa aattgtctgt tgaggaaatc
     7441 gcccagcatt tagcggtcaa tcggagccat ttgtcgcgag tattcaaaaa tcatatgggt
     7501 accagtatca aggaatattt gatcggggta cggatcaatc gaggggcgtt tcttctttct
     7561 ctgacggatg aatccgtgga aagtattgcc tatcaagtag ggttcaatag tctagtcgta
     7621 tttagccgaa tgttcaaaaa gagtaccgga gaaacggcta cgaactatcg taaacgtatg
     7681 aaaaacgaaa attttaagaa tattgctttg gataccttga aaaaacagtt ggaaaaacaa
     7741 accgcagttt cttggacaac ctgattagtc tggttaaaat gacaagcatc ggcaaaagaa
     7801 acttgtggcg gttatgctac actgtaaagc gaagactaaa aaggaggaaa agggatgcgt
     7861 acacttatca tcattagcca tccaacgatc gaagaatctt taaatcagca atttttcaaa
     7921 gaagcttctg ctggtttacc agctacttgg catcatttgg aatcaagtta tccagacgga
     7981 aaaatagata tagagactga actacagctc ttggcccagc atgatcggat cattttccag
     8041 tttccgtttt actggtatag ttctcctgct catttaaaaa tttggcaaga taatgtcttg
     8101 gaacgagcag cacatgtatt aaaagggaaa gaactaggaa tcgtattgac aacaggtgtg
     8161 gcggaaaaag aataccaagc tggaggaaaa gaagaatata cgatttccga atttttgagg
     8221 ccgtatcagc gaatcgcaaa taaattccat atgacctatc ttccgccatt cgttttagca
     8281 caatttatgt atttatccca ggaaaaacgt tgggagaagc taattgctta tcagcagtat
     8341 ctctcattgg aaggcaaacc atcgctgact cagcggattg actggtttat tcaaagagta
     8401 caggaaaatc agaaaatgca ggaagaagaa tctgaaaaac aagcatatat cgtagaagca
     8461 ctgactgagg caaaagagca gatcgaagac ttgaccttta cactgcaaga aatgaaagga
     8521 acttcattat gacaaatgat tggctgatcc aacaattaga tgaattaagc gaaaaatcag
     8581 aatatcaaga ccgtgcgctc ttatatgaaa taaagaaact gatggctgag atagacgaac
     8641 gaacaatgca gctgcaagga gaaatcgacg gacaatcttg gaatcatctc aactggtgaa
     8701 attttcttat aaataacaaa gataaaaatg tgcacagcga caattatttg ctacaataag
     8761 aatatgaagc gtttgataac gctattatac ataaaaattg gtggtgaaaa aaatgtatga
     8821 tgaaaatgag tggggagaaa atgttcggat gacccgaaga agacagcaaa aacaggcagc
     8881 tcgtaagcgg atgatcatga ttggggcagc agttgccgtg tttttgatca tagcaggagg
     8941 agttgcgggt ctatattttc atggaaaaaa ttcgtcagaa gcgaaaagta cgaccataac
     9001 ggaaacaacg acaaagaaaa cagagacgaa acaaacaagt gagtcatcaa ctaaaacaaa
     9061 agagacacaa acttctgaag aaaaaacagc aaatggtttg ccagagcaac ttcaagcaat
     9121 cgtaaatgat tattcgaaaa agatcgaaga aaagacgcct gcattgattg aagaatacca
     9181 gacagaaatt cagggaaatc aagagggaat agctggttta tcagcagttg ctaaccaaaa
     9241 agcacgtgag cttcaagcaa tctccgacga agggatcaga aaattacgtg cagcgtatca
     9301 ggcagcagaa aataaagacg gtgtagactt agatactttg atcaatcaat tatcggctaa
     9361 ttatacgaat catgtcgcta agatttccga tatttatttg cagactagcg cctctcttca
     9421 agcagagtca acaagcacac aagacacaac atcttctgat tctgagacag cagagtcggt
     9481 agaagcttct gaaatgcaag ctcgaacaac acaagacaca acagattcct ctgaaactaa
     9541 taccaacagc gcgacttcac aggctgcgac aaccgtagtt ttggaaggag aaggtccaaa
     9601 tcaaatagcc gaacgaactg gcgtaccagt agaaacgatc ttgtcgctga atgggatgag
     9661 catggagaat tatttcctga ctcccggtga gacgctaaaa ttgaattgat aaaagcaata
     9721 aaaaagaacg aagcttccac taaggtgaag cttcgttctt tttttatttt ccggttcttt
     9781 tttcgcgtac aaagtaatgg atcgtcatgt aaagcaagaa aacgagtcca ataatcaatg
     9841 agattctcgt ttcaggattg ataaacatga aaatcaatac gatagctaaa aaagcaagtg
     9901 tcacataatt cgtataagga gatagtggca ttttaaaagg atgatcatgc attttatctg
     9961 cgtgcttctt tttgaagcga atctcgctga tcaaaatcac tacccaagga accataccag
    10021 gcaaaatact tgagctgtat acgaaaacga aaatattttc tgactggttg atgaacattg
    10081 gtagaagata atttaagatc agaccaatta agattccacc tgagattgct acgacaggat
    10141 aaaaaggcgc accgtgacga gatagtttca gaaatttttt agacatcttt ccatttatgg
    10201 caagtgtata gaccatacga cttgcgctga aaatccctga attgcaacct gataatgccg
    10261 ctgtaatcac gacaaaatta atcagtcctg cagcaaatgt aatgccgact ttagaaaaag
    10321 tttgtacaaa aggtgaacca atctcactca attgattcca cggatagata ctcacaatga
    10381 taaaaatagc accaatataa aaaatcaaga ttcgaccgat agtggactgg acagcttcaa
    10441 tgatcgtctt tttaggattc tctgcttcac cagcagtcat tccgatcagt tcgattcctt
    10501 gataggaagc aacaacgatc gataatgcaa agaaaaatcc tttgacgcct ccagtgaaga
    10561 atccaccatt tttccaaaga tttgaaatcc ctactgcctg accatgatta ccaaatccaa
    10621 ataagattac cccaagacct gcaatgatca tcaaaatgat cgttatgact ttgatgatcg
    10681 aaaaccaaaa ttctaattcg ccaaacgcct tgacagaaat aagatttgcc agcataagaa
    10741 acaagacgac aatgattccg ggaataattg ccggcaaatc aggccaccaa taattcatat
    10801 aagatcctac agcaatcact tcacttattc ctacgacaat atattgaaaa atattactcc
    10861 aagcggtcaa gtagccagcc acaggatgga tgtactcgct cgcgtaattt gcaaaagaac
    10921 cagtcgaagg atcaacgtaa agcatttcgc ctaaagcacg cataatcaaa tacaaaaaga
    10981 atcctgcaat cgcataggct cccatcactg agggccctgt ccaacgtatg gttgaggagg
    11041 cacccataaa cagaccgaca ccgatcgttc cacctagtgc gatcatttgg atatgacggg
    11101 cactaagact tcgagttaac ttttcttctt ccatacaaaa actcctttcg ttgttgagtc
    11161 aacaagaaaa aataatcaaa cgtttcaaca catgtttttc attattaggt tagccttatt
    11221 gaactcttga tgtgattcta cagaaaattt tcataaaatg cgaggaaaat tcgaaaaaaa
    11281 ctttttcatc attctacttg aaaatgcttt ccattttagt taaactatat ttaaataaaa
    11341 agttaggtaa acctaaaaag gagtgtaaga tttggaacgt acggccattg taattcaaga
    11401 cctttcagcc gcttatcaag ggaaaactgt tttgaaaact atcaacttga cgataaatcc
    11461 acaaaaaatt accggtatta tcggaccaaa cggtgcagga aaatcaacat ttatgaaatc
    11521 tttgctagag ttgataccag ctactactgg taaagtcacc ttttctggac agtcggtaaa
    11581 ctcagtccgt aaaaaaatag cctacgtgga acagcgaagt gaattggatc tttcctttcc
    11641 aattgatgta ttaggcgttg tacttttagg aacatatcca tctttacgaa ttggacaaag
    11701 acctgggaaa aaagaaaaag aacgtgcaag acaagctttg aaaaaagtag ggatggaaga
    11761 atatgccaaa agacagatca gcgaactatc gggtggacag cttcagagag tttttattgc
    11821 aagagctcta gcccaaggag cagaatggat ctttttagat gaaccattcg tagggattga
    11881 tgcgttaagt gaacgaaaga tctttgacat cttgcaggaa ttgaagaatt caggaaaaac
    11941 gattttgatc gtccatcatg atcttcataa agtagaagaa tatttcgatg aggttattct
    12001 tttaaataaa cagctgatcg cttccggtcc agtacaagaa gtctttacat cgaagaacct
    12061 tcaattggcc tatggtgaga tcatcagaca tttagtaaaa ggaggagaga aaaaatgatc
    12121 caatccttta ttgatggatt aatgaattat caattcctgc aatacgcttt ggtcacttcc
    12181 atgcttgtag gacttgcttc tggagtcatc ggttctttta ttattttacg agggatgtct
    12241 ttgatgggag acgctatctc tcacgcagtt cttccaggtg tagccatttc ttatatgttt
    12301 ggttttagtt acatctttgg agccactgct tttgggatgc taacagcagc agtgattggt
    12361 ttcgtgactc agcggagccg attgaaaaat gatacagcga ttggaattgt ctttagctcc
    12421 ttttttgcat tagggattat cttgatttca tatgcccaga gtgcgacaga tttgtatcat
    12481 attttatttg ggaatgtctt agctgttagg gaaagcgatt tgttgctgac agcactcgtt
    12541 agtggaatcg tcttgatatt tgtctttttc ttttataaag aattgaagat cacatcattc
    12601 gatccgacaa tggcaaaagc ttatgggctg aacacatcgc tgatccatta tcttttgatg
    12661 ttctttttga cattagtggc tgtagtcagt ttacagacag taggaacaat cttggtgatt
    12721 gccatgttga tcacaccagc cgccacggct tacttgctaa cgaaccattt actgaaaatg
    12781 atcattacag ctgcaggaat cggtatgcta agtgcagttg tcggtgtgtt tttcagttat
    12841 agttacaatt ggccatcagg agctacgatc gtgttagcat gtaccgcatt ttttatcctt
    12901 gcttttttat tttctccaac aaaaggaatt ttatttcaga aaggaagcag atagatgaaa
    12961 acaaaaaaat cactcttttt aatcttggca gttagtttct tggtattagc cggttgcgga
    13021 aagcaggctt ctgaccaagc ggatgaagga agtaaagaaa agttgtcagt cgtggctacc
    13081 aattcgatct tggcggacat ggcaaaagag gtcggaacag atcaaataga tatccacagt
    13141 atcgtaccag tcggaacaga tccgcatgaa tatgaagtac taccagaaga catcaaaaag
    13201 gcaagcgatg cagatgttat tttatacaac ggtttgaatc ttgaaacagg taacagctgg
    13261 ttcgataact tgatggaaac ggctaaaaaa gaagaaggaa aagattattt tgcagttagc
    13321 aaaaatgtag aacctcttta tttaactagc ggtgaagaac atacaaaagc agatccccat
    13381 gcttggctag acctatctaa cggaataaaa tatgtggagg aaatcgcacg tatattctct
    13441 gaaaaagatg cagaaaatgc gacactctat aaaaaaaatg cagaagcata tgtggaaaaa
    13501 ctaaaagaat tagatacaca agcgaaggaa agttttgctt ctatcgaaga gaacaaaaaa
    13561 ttattagtaa caagtgaagg ggcattcaag tatttttcac gagcatatga tttgccagca
    13621 gcttatatat gggagatcaa tacagaaagt caaggtacgc ctgatcaaat gaaagcgatc
    13681 attgatcaga taagagcaaa agaagtaccg gttttattcg tggaaaccag tgtagactca
    13741 agaagcatgg aacgggtagc aaaagaaacg ggtttgaaaa tctatgataa actgttcact
    13801 gattccatag caaaagaagg agaacaagga gattcttact atcagatgat gaaatggaat
    13861 attgaaacga tccatgaagg tttgtcacaa acaaaagaaa gctgaaaagt gcaaggtcta
    13921 gcttgaggag cagaccttgc attttttata agagatatga aaaaaaatta tgctgttttt
    13981 cgtcgtacag ataccttttt tgaagaaatt ccgttatagt tagagtaagg aaggaaggtg
    14041 tggctatgaa ttttacacgt aaagataaat atacgattaa agaagaagtc tttcgattga
    14101 tcagccagca ggaaaatacc gacaaggatc aagaccttca atttcttgaa gcagaattag
    14161 ctaaattatt catagcaaat caaaatgaga caacagaacc agatgaagag ctgtacatag
    14221 gcaaatggtt gtttgatgaa tttcagcctt tagatgaaaa taccggtatc ggttattttg
    14281 tgttcctttc tccagtcggc ttcacacctg gcgtattagt taaacaaaac gacgaaataa
    14341 ccgtcaaagc atggcctgca ttattttcag tcatcaaagc agaaggagta atcaaaaaga
    14401 tccagtcggc ctattataaa agtcaattta ttgccaacag caaattaatg aatatgtttt
    14461 ataatcgtct agtagaaatt gctaggcctg ggaaaatccc gcaaacattc acgtacacac
    14521 agcaaaaaaa tctctatgaa gaagtattgt attcccgcga tctgtctgag ttttcgccat
    14581 gggaagaggt aaggctccat gaactgttaa gtacaaaacc agtttcattg aattttttta
    14641 atgcattaga taacaaaaga aaattaattt caacaaatta ttgggaagta tttgctgcaa
    14701 gaaaaaaatg gatggaagaa aagaagattg ccgatcagca gatccagttt gtccagctga
    14761 aaaaagaaaa actatattat gggttataca gccgttaaca gcaagcgagg aagaccatga
    14821 cattaaaaga agaaatcata caagaaagca aacgattagg aattgacaaa atcgggttca
    14881 ccacggcgga accttttgat tcattaaaag aatcgttgga agaacaaaaa gcagctggcc
    14941 atacttctgg ctttgaacat ccaaatatcg atgagcgtct ttatccagaa atgacatttg
    15001 atcagccgaa atcgatcatt tccattgcac ttgcgtatcc tactaggatc catgaagaag
    15061 tgcctaggga tgaaaaacgc gggcagtttg ctcgtgcttc ttgggggatc gattaccatg
    15121 atatactcag agaccgtttg aaccgattga tcgaattcat ccaaacaaga gcagaaaaat
    15181 ggcaaaaaga agaggaatgg cgtctagctc cgcaagtaga tactggagaa ctgatcgatg
    15241 tcgctgtagc acagcgagct ggtttaggat ttattggacg aaacggattg ttgatcactg
    15301 aagagttcgg ttcatttgtc tatcttggtg agatcgttac taatattgta tttgagcctg
    15361 ataaaccagg agaatttggt tgcggtgact gtatgcgctg cgtgactgct tgtccgacaa
    15421 aagcattgct tggtgacgga agaatgaatg cccagcgatg tttgtcttat caaactcaga
    15481 caaaagggat gatgccggaa gaatatcgta aaaaaatgcg aaatgtcatt tatggatgtg
    15541 atatctgcca gttagtctgc ccttacaatc aaggaaaaga ttttcatttt catgaagaga
    15601 tggaaccaaa agtagacgaa atatatccaa aattaaagcc aatgctttcg atgtctaata
    15661 aagacttcaa acagcaattt gggcatttag ctggttcatg gcgtgggaag aaacctttgc
    15721 agagaaacgc attgattgct ttagctaatc taggtgatcg aacggcattg cctgagattt
    15781 cagaatgttt aacagatgtc cgccctgtca tcagaggaac agcagcttgg gctattggac
    15841 gtctaggaac aaaagaaccg gaaaaatggc ttgatgtatt agatgaaata ttagctaaag
    15901 aaacagaaga agtcgttata aacgaattgg aacatgccca gaaattattg cggagaaagt
    15961 taaaataaaa aaatagttaa cattattcaa agttttt
//
LOCUS       DADLIO010000058        15742 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.061, whole genome shotgun sequence.
ACCESSION   DADLIO010000058 DADLIO010000000
VERSION     DADLIO010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15742
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.061"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(24..722)
                     /locus_tag="JOX41_002086"
     CDS             complement(24..722)
                     /locus_tag="JOX41_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobyric acid synthase"
                     /protein_id="HAY6449808.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(715..2067)
                     /locus_tag="JOX41_002087"
     CDS             complement(715..2067)
                     /locus_tag="JOX41_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HAY6449809.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(2290..3690)
                     /locus_tag="JOX41_002088"
     CDS             complement(2290..3690)
                     /locus_tag="JOX41_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HAY6449810.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            3851..4588
                     /locus_tag="JOX41_002089"
     CDS             3851..4588
                     /locus_tag="JOX41_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HAY6449811.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            4713..5192
                     /locus_tag="JOX41_002090"
     CDS             4713..5192
                     /locus_tag="JOX41_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HAY6449812.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            5189..5956
                     /locus_tag="JOX41_002091"
     CDS             5189..5956
                     /locus_tag="JOX41_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449813.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            6186..6755
                     /gene="lepB"
                     /locus_tag="JOX41_002092"
     CDS             6186..6755
                     /gene="lepB"
                     /locus_tag="JOX41_002092"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAY6449814.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(6859..7461)
                     /locus_tag="JOX41_002093"
     CDS             complement(6859..7461)
                     /locus_tag="JOX41_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAY6449815.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            7567..8036
                     /locus_tag="JOX41_002094"
                     /pseudo
     CDS             7567..8036
                     /locus_tag="JOX41_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            8142..8726
                     /locus_tag="JOX41_002095"
     CDS             8142..8726
                     /locus_tag="JOX41_002095"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HAY6449816.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            8729..9802
                     /gene="prfA"
                     /locus_tag="JOX41_002096"
     CDS             8729..9802
                     /gene="prfA"
                     /locus_tag="JOX41_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HAY6449817.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            9795..10634
                     /gene="prmC"
                     /locus_tag="JOX41_002097"
     CDS             9795..10634
                     /gene="prmC"
                     /locus_tag="JOX41_002097"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HAY6449818.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            10627..10806
                     /locus_tag="JOX41_002098"
     CDS             10627..10806
                     /locus_tag="JOX41_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449819.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            10828..11853
                     /locus_tag="JOX41_002099"
     CDS             10828..11853
                     /locus_tag="JOX41_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HAY6449820.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            12028..13272
                     /locus_tag="JOX41_002100"
     CDS             12028..13272
                     /locus_tag="JOX41_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HAY6449821.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            13425..14372
                     /locus_tag="JOX41_002101"
     CDS             13425..14372
                     /locus_tag="JOX41_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAY6449822.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            14506..15135
                     /gene="upp"
                     /locus_tag="JOX41_002102"
     CDS             14506..15135
                     /gene="upp"
                     /locus_tag="JOX41_002102"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HAY6449823.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(15274..15516)
                     /locus_tag="JOX41_002103"
     CDS             complement(15274..15516)
                     /locus_tag="JOX41_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449824.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            15637..15709
                     /locus_tag="JOX41_002104"
     tRNA            15637..15709
                     /locus_tag="JOX41_002104"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:15670..15672,aa:Thr,seq:cgt)
BASE COUNT         5349 a         2823 c         3195 g         4375 t
ORIGIN      
        1 tcacattccc ctttttcgaa taactaggct gtttgtcctt caagataggg cagatccaat
       61 tctttaccgt aacgttgttc taaagctagg cggatcaaac gagctgccag gttctcattt
      121 cttgcaagga taggtccatg gaaataagaa ccgaagacat ttcggtaaat gacaccttca
      181 gattggtctt caccattatt tccttgacct tgtaccactt tccccaaagg tcgttcacct
      241 tcacctaaga aagtccgacc attgtggttt tcaaatccat aataagtttc attgaattct
      301 tcgttatgga taacgatatc accgataaac cggttatttt cctgacttaa cgtgtagtga
      361 tccagtgcac tgattccttg gatcttttct ccattagctc ccatgtagta gtgacctagc
      421 aattggtagc caccacaaat ggctaacatg acgccatcat tttcgatata gttgatcaaa
      481 gaatctttct ttttctggat gtcttttgaa atgattaatt gctcaaagtc ttgaccaccg
      541 ccaaagaaaa ccaagtcata tttatcagca tcaaaaggtt catgtatact aacgatctcc
      601 gtatggcaag aaacccccat tttttctgct atatatttca acatcaaaag gtttccgtta
      661 tcaccatatg tgttcatcaa atttccataa aggtgggcga tattgagttc ataattagcc
      721 acggttcatt cctcctttga taaatccttg agcagctagt tctttacgaa gctgcaatac
      781 agcagtgtaa gtagctaaaa tatagacatg ctcagttggc aattctttga ttttttcgat
      841 tacttctggt aattcttttg tttctgtcaa tttattttct ggaatcccgg caacttttag
      901 acgtaaagtc atatctgtat gacggtctcc tccagaaata acagctggga tatccatatc
      961 ggcaaagttt tcaaaattac catcccaaat ccagctgaca tcgattccgt ctgcgtaatt
     1021 ggcatttaat aaagccacta aagaaaatgg ataaggagct agaccaatca tatcgattac
     1081 ttgattgata cctacaggat ttttgacaag tactaatgta cattttttcc cattgatatt
     1141 gatgacttct tgtcggccga atactttctc gtcatatcct aaaccttgtt tgattttatc
     1201 aggatcgaca ttgaagtact ctgccactgc agtagctgct aaagcattgt agacattata
     1261 cataccgcca acttcgattc cgtattcatg accatcgatc acgaaatctg ctgacacatt
     1321 gtccatccgt accatatcag ttaatcgata atccaattca ggacgtttga agtcacaatt
     1381 tggacagtaa tatttcccta agtttgcata agtgatcatt ttataatgca agatgtgatg
     1441 acaatttgga cataagacac cgtctgtatt gtaatgagcc atttgttcac gatcttcttc
     1501 atggtcaaag ccataatatt ttctaggatt gactgtttcg atagaattga agattggtga
     1561 atcaccgtta ctgataatcg ttgcatttgg tgactttgcg gcaccgtcta caatcatttt
     1621 ataggtcgta tagatttctc cataccgatc catttgatca cggaaaatat ttgtaaataa
     1681 gaacagttct ggtttcatat attctgtgac tttgctcaaa cttgcttcat ctatttctag
     1741 gacagcaaac tttttctgtc ctttttttgg ttttgcctgc aagaaagtcg atacaattcc
     1801 ctgtaccata ttcgcaccag tagggttggt tagaacttca tcgaattgct ggcgcaaaat
     1861 attgactgtt aaagcggtag tcaatgtttt accgtttgtt ccggtgacaa cgacgacttg
     1921 gtagtctttt gccaaactat ctagtatatg tggatcgact ttcagcgcta gtttacctgg
     1981 taaacttgat ccgcctttaa aaaaagtttt taatgcccat tgcgacgttt ttccaactgc
     2041 aatcgcaaaa tgactgcgta ttcccattat gtaacctcca aaaacgattt gctgacgaat
     2101 aaattcaact aatcatacca tatgttgaaa aaaaggttaa attgcttttc ttattcttaa
     2161 gaaaaggtta cggctgaaag tgcatgaaat cggacaaaat cgcatgattt aacaaaaaaa
     2221 cagcttgaaa caaaatgatt gtttcaagct gctgtgattt tattattccc tcttacctat
     2281 attcccattt taaccgataa taattttctc gcttggatat tcatagccta gatctcgtgt
     2341 ttcttttggc acgaataaca tcaatgtata tagcattccg atccgcccaa taaacatcag
     2401 tgtagcaatc gtgattttgc ccacaacaga caagtctccg gtaatcccta aagataaacc
     2461 agttgttcca aacgcagaag ttacttcgat gatgatcgag atcagcgttt gttcttctgt
     2521 agcagataaa aaaacgatac aaaagaaaca cataccaaga gaaagcataa agacaacgac
     2581 tgattttcgc acatcatctt gatcgattct ccgtccaaaa atattgatgt tatcttcact
     2641 tttgaggaag gaatatagat acaaaccgat gattgctaca gtagttgttc gaatcccgcc
     2701 gcctacagaa ctaggactgc atccgataaa catcagtaaa gaaaaaatga tcagtgttgt
     2761 gatttgaaaa tcacccaaat cgtgaatctg cagaccagca ttacgagtcg taatcgaata
     2821 aaacatcgaa ttgatccatt tgacactcat attggaatct tggaataaat ggtccttttc
     2881 caatagataa atcaagacag ttcccgaaac aaacaagata acaaaagcta acacagctaa
     2941 tttggtaaac aaggaaaaac gaaacggaag cttcgcattg gaacgtttgt ataatagcca
     3001 ttcccggcac tccatcaata caggaaaacc aattcctccg acaaaaatca aaaacatgat
     3061 caggatcaag aaaaaatagt catgtgcaaa gggcttgatg gaatccccag tgacgtcaaa
     3121 cccagagttc gtgacagccg atatcgcctg ataaaaaccg taaaaaacgg catcacgcca
     3181 acgatcaaaa tagcctctgt aataaaaata aatagaaaag aatgtcccaa aaagtaattg
     3241 aaaccagatt aaaatagcaa aagtgatccg aatcagtcgg acgataccag acaaacgcgg
     3301 ttgattcata tccgtcatga tcagctgtcg ctgtttcagt gtgatccgtc gtttagaaaa
     3361 aatgacaaaa gcagtagaaa tcatcatgat ccccaaacca ccaacttgaa ataatatttc
     3421 cagcagtata ataccgttat cattgaacac agaattgata tcaaaagtcg atagtccagt
     3481 cacactcact gtactgattg ccatgaacag catgtccaca aaagaaacat ggctatctgg
     3541 ttcgcgaaaa atcggcatat aaaatagaac gagtgataag accgtcatca atatataata
     3601 aaaaacgatg atttggatcg atgagaaatg attggcagca aacttctgtc ctcgccgctg
     3661 cagccttcga aagaataaat caacatgcac agtactatcc tcctgacaat agtcgtttct
     3721 accagtatac aaggggaatt aggaatactc aaagaaatta tcaaacagat aacaatacag
     3781 ctttcgatta aaatagaaat ggcttataat aaggaaaatc ctagaaaaaa gaaggaggag
     3841 gaataacaaa ttgattaatg ctcaacaaat cgtagaaaaa atgaaaaatc aaaaaataaa
     3901 ttatgataca gttctgaaaa aaatgatcat gcaatgggag aaagaagaag taaagcctaa
     3961 gatattaata catacatgct gtgctccttg cagtacgcac acattggaat tcatgtctca
     4021 atatgcagag atcacgttat ttttttcaaa ttcgaatatt catcctaaaa gtgagtattt
     4081 gcgaagatta catgaacaaa aacgatttgt agaccaattt aatgagaaaa ctgaccatca
     4141 tgttgcgcta atcgttgatg aataccgtcc aaatgaattc accaaaatgg ttttaacaaa
     4201 ccatcttgaa aacgaaaaag aaggtggtgc tcgctgcagt gcatgcttca atatgcgatt
     4261 agatcttgtt gcgcaaaaag cgcaagaact aggatacgat tactttggaa gtgccctgac
     4321 catctcgcca aagaaaaatg cagctttgat caatcagatc ggaatggata tccaaaagat
     4381 ttacgggaca caatacttgc caagtgattt caagaaaaac aaaggctatg aacgctcttt
     4441 gcaaatgtgc aaagagtatg atatttatcg ccaatgttat tgtggttgcg tgttcgctgc
     4501 caagcagcaa ggatgcgatc tgaaagaaat caatcgggaa gcaaaagctt acttaaaaac
     4561 atcaaccgta gtttttgagg aaaattaaag aaatctttcg gaaaaacgta agaaaaaaat
     4621 aaagaattta tggtagaaat aaggtagact gtataatttg tccgtagtaa agtaaggaaa
     4681 caagaataaa tttcaatgaa ggaagagata agatgcgaaa agtagcacct attttgaagc
     4741 caatcgctgt attaacaatc tcgacgattg tcgcgactac tacaggtatt gtgaatagtt
     4801 ccagctaccg tgcaccaagt tcaagttcta gtactgtaga agaaacaaca ccaactactt
     4861 cagtctcgac atctgaacca acaacaacgg aaagtttgaa tgaaaccact acgacaagta
     4921 catgggacga tacaacaact agttcgtcgt atgatgagac atatacaact gacagctcaa
     4981 gcgaaacaag taatacggta ccagatggca ctccatcgga ttcaaccaat ccaagtacaa
     5041 gtccggatac aagtgctagc tccgaaacga taccaagcag tacgactgta gatgataaca
     5101 cgcaaaatga tgatgcagca cgtacagcac agcaaaacca agattcagga aatacccaaa
     5161 cgtataacca gcaagcaggt gattctcaat gacattttta ctagacctta tcaacggggt
     5221 gcataaattc cttggctatt tagacatcag tcctaaatat cttaaccgtg gatatacgat
     5281 tttaagtgtg attcccacgc tttatttatt gagaattgtt tatggacttt ggcaaaacca
     5341 aaactatctt caatttttct tatatggact tgcatttcta gtgcttgttt attttactgt
     5401 tttaaatgta ttttattact ttttagataa aaacacgaaa gccgatgtca ctcagctttt
     5461 tgtgaagtat ttacctgatg aagcgttcaa catccagaca gaagaatcga tagataatgg
     5521 aaattcgatc gataaagtga atacacaaga ggtcatggtt tcttatgacg aagattatca
     5581 attgaaatta gccgagaata tgcggtattt gattggaaat ggtgagatca aaacaaatga
     5641 actcggtcgc atggatggat ttctggtcga tagaaataca ttgtatcctt attactatgt
     5701 caagaaaaca ggagagaaag agtatgttct aaatattgga cgaagctact cggacatgga
     5761 aaaagtaggg accattcgac ttgactcaac agaagacaca ttggaacctg tcggattgtt
     5821 catcgtcggc ggtgattttg tcaaagacgg gttacgctat catgagcctt atcgtctgaa
     5881 attgattgca aaaaaggcac agtcgcagga agaaccagtg gtttatagtc gtagccaaag
     5941 aagaagacat tcataatgtg atgaaacgcc gtgtatcagt ggttgcgata aaaacgttta
     6001 ttcggaataa gggggatgtg acacgtcttt tgtcacgttc cttttttata taacgagaaa
     6061 gataagacga acacatcact tattctttcc tttcatttat aaacattgta gaataaagaa
     6121 agtacaacga agtattgtga aaaaacgtaa taaataacga ggaaaataca agtaggaggt
     6181 aagctgtgaa agaatttttg aaaaattggg ggattttgat ccttgtatta gcggctattt
     6241 tattagctag agtgtacgtg tttacaccag ttactgtaaa cgggcattcg atggacccta
     6301 cattaagtga tggacaacga ttgatttcat ctaagatctc aaactatgaa cgaatggata
     6361 ttattactac aaaggaaccg ggggatgaag aacggatgat tgttaaacgg atcatcggta
     6421 tgcctggaga tacagtcaag atggaaaatg accagttgac cattaatggc aaaaagtatg
     6481 atgaacctta tctggatgag ttcaaaaaag aattttcaga agataagtta caaggagaat
     6541 atgcttatag ctcaggattc caagcacaag cagaaagttc atccaccttt acgagtgact
     6601 ttgaatatac tgtgccaaaa ggaaagtatc ttgttctagg cgataaccgc ttgatttcaa
     6661 aagacagccg aatgtttggg ttagtcgaca aagatatgat ccaaggaaaa gttgttttcc
     6721 gttattggcc tctttcagaa attaaaatca tgtgatgaaa aaataaaaag aagctgtgac
     6781 atgttttttg tcacagcttc tttttccgaa aattccttct tatttcttgg agttgctcac
     6841 tttttttgca atctcatttt aagctttttg gctgatggat aagaaaagcg aagcgttttt
     6901 gttcataaat agcttttccc cacgatggaa ggtatgacta gtagcagaga caaagcccgt
     6961 tttttccaat cgattattca attcttcttg gctaaagcca ttatggactt tcggatgact
     7021 aatttgttca ttcttgtcaa agtctacgat gatcaattga ccgccaggag ctaaaatttc
     7081 ataaagtttt gtaagaatat tctccgtatc aggaatgtgt aaaagtacaa gtgatagaag
     7141 gatgagatta gcttggacag caggaaattc gacagaagca tcagcgtgga tcgttcggac
     7201 atttttcaga tctgctgctt ggatcttttc ttctgccatt ttcagcatag tttctgaagc
     7261 atcggcaatg atcagttctt tgaatctttc cgcaagcggt aaactaacaa gcccagttcc
     7321 gcctccgtaa tccagcagga ctttttggtg gctgtcgcgc ggtagataag tagttagttc
     7381 ttcgcgaata atcttggcta atgcttgacg gtcaggggaa tcataatggt tagcgatgga
     7441 atcaaaaata ttttttgtca tcaaatagct ccttacgtaa aactttgaaa ttttaactta
     7501 ttatagcacg tgaaaagaaa gaaagcatgc tatactcaat tcaaaaaggg agaatctaga
     7561 aagaatatgc cgatatcgtt tgtaaaagat agagaggaaa aaggaaagtg tgtccgagaa
     7621 atattactag acttgcctga gtggtttggg cttcctgaat caacggaaaa atatatcgag
     7681 gaatcaagta aactaccttt atggtgtgaa aaaagaaaag aagaatattt aggctttatc
     7741 actctttcac agacaagtga agatactgcc gaaatctatt ctattgtatg ggaataaaaa
     7801 aagactatca tcaccaagga ttaggaacaa aactttttaa agaagcagaa ggttacgcag
     7861 caaaacatta caaatatttg caagtgaaga ctgtagacga ggggcactac tctatatatg
     7921 atcaaactat ttgtttctac gaatcattag gattttcaag gttggaagtt tttccaaatt
     7981 tatgggatga atggaaccca tgtttagttc ttgtcaaaaa attggaacaa aagtgagcaa
     8041 tagatttaat actaatctgt gcttgatgaa aattctcact gtaaaaaatg ctgaaaatca
     8101 agtataatac cataggaaca aactggaagg tgaaaaagag catggcacaa ctatttttta
     8161 agtatggcgc aatgaatagc ggcaagacga tcgagatcct aaaagtcgca cataattatg
     8221 aagaacaaaa taagccagtt gtcttaatga caagcggtat tgatacaaga gatggtttag
     8281 gcgttgtttc aagccgaatc ggactgaaac gtaatgcgat gccgatattt gaagaaacag
     8341 acgtatttga cgtaattcag aaaatggaaa gcaaacccta ttgtgtgctg atcgatgaag
     8401 cgcaattctt aaaaaagaaa catgtcattg cttttacgag aattgtggac gaattggata
     8461 ttccggttat ggcatttggt ttgaaaaatg attttcgaaa cgagttattt gaaggatcaa
     8521 aatatttatt gctttatgca gacaaaatcg aagaaatgaa aacaatctgt tggttctgcc
     8581 acaaaaaagc aatcatgaat ttacattata ttgatggaaa ccctgtttat gaaggcgatc
     8641 aagtgcaaat tggcggaaat gaagcttatt accccgtttg tcgaaaacat tactttcacc
     8701 catcaatgat tacagaagga gaataagcat gtacgatcaa ttacaagcaa ttgaagaccg
     8761 ttatgaagag cttggagaac ttttaagtga cccagaagtg atttctgata caaagcgttt
     8821 tatgcagctt tcaaaagaag aagcaaacac gcgcgaaaca gtcgaagttt atcgtcgtta
     8881 taaagaagta gtacaaggaa tcaccgatac agaagaactg cttggtgaaa aactggatga
     8941 tgaaatggct gaactagcaa aagaagaatt atctgaatta aaaaaagaaa aagaagtctt
     9001 agaagaaaaa atcaagatct tgcttttacc aaaagatcca aatgacgata aaaatatcat
     9061 catggaaatc cgtggagcag caggcggaga cgaagcagca ttattcgctg gcgatctttt
     9121 caatatgtac caaaagtatg ctgaagcaca aggctggaaa acagaagtga tggaagctaa
     9181 cgttaccgga atcggtggat ataaagaagt gatcatgatg atcaccggag acaacgtata
     9241 ttcgaaatta aaatatgaaa gtggtgcgca ccgcgtccag cgtgttcctt caactgaatc
     9301 gcaagggcgt atccatactt ccaccgcaac agttgtcgtg atgccagaag ctgaagaagt
     9361 agagatcgat attgaagaca aagatatccg tacagatatc tatcatgctt caggtgctgg
     9421 cggacagcac gtcaataaaa cagcatctgc tgtacgtttg actcacttac caacagggat
     9481 cgttgttgct atgcaagatg aacgttctca aatcaagaac cgtgaaaaag caatgaaaat
     9541 cttgcgtgct cgtgtgtacg ataagatcca gcaagaagca caaagcgagt atgatgccaa
     9601 tcgaaaatca gcagtcggaa ctggggatcg ttcagaacgg atccggacgt ataatttccc
     9661 gcaaaatcgt gtgactgatc atcgtatcgg attaactatc caaaaattag atcagatttt
     9721 agcagggaaa ttagatgaga tcgttgatgc attgatcatg tatgatcaaa catcaaaact
     9781 ggaagctatg caaaatgggt aaaatgacct atcgagaagt cctgtcacgg gcttcttctt
     9841 ttttagagga tcatgggaaa gaagcatata gtatccaatt tttatttttg gaacgaaaac
     9901 aatggaaaaa acttgattgg ctccttcata tgaacgaaga gatttcagaa gaagaacagc
     9961 ggttgatcga aaccgatctg cgacttctgc ttgcagatca tccacctcag tatttgctag
    10021 gatatgcaga tttttatgat catcggttaa aggtaactga agcaacactg atccctcgac
    10081 cagaaacaga ggagttagtc gaatggtgtt tagacgagac gcctggtgta ccgttagaag
    10141 tgatagatat tgggacaggg actggagcaa ttgctattag tttgaaagca gcaagaaaaa
    10201 attggcatat atctgctgtg gatctttcag aagaagcatt agaagtagcg aaagaaaatg
    10261 ctcagaaaga aggaacgaaa atcagttttt atcatggaga tacattagga ccagtaatgg
    10321 atcagcaatt tgatgtgatt atttctaatc cgccgtacat cagtcggaat gaatgggaac
    10381 tgatggatga aagtgtccgg tcattcgaac ctaaaatggc cctttttgct gagaacgatg
    10441 gattagctat ttatgaaaaa atagcagttg aagcaccaag cgtactaaaa tcaaatggaa
    10501 agattttttt agaaatcgga tttcgccaag gtgaagcagt aaaaaaaata tttcagcaag
    10561 catttccaga taaaaaagtg gcgataaaaa aggatctttt tggcaatgaa cgaatgatcc
    10621 aagtttatgg ttgaagttgt ggatgaaaaa ttttttattt gtttttttat tataaaaaaa
    10681 cacttatttg acaaggatgt aaacgacttt ttggtttatc aacaagttta tccactattg
    10741 acaaatagat tatccacaaa cagtggaaaa cttgaggata aactcagaca aaataagaat
    10801 gtatgaaaaa ggggttgtgg ataaactgtg gaaacgaaac gatatgatga aacagaattg
    10861 caagaggcag ccgaagcact gaaagaagga gaacttgttg cttttcctac cgaaacagta
    10921 tacggattgg gcgccaacgc tcttttacca aacgctgtca agaaagtgtt ttctgtaaaa
    10981 gggagaccgc aagataatcc attaatcgtc catgtcgcct cttttgaaca agtaaaagag
    11041 tatgtggaca actttcatcc ggcagcagag aagattgtga agaacttctg gcctggacca
    11101 ttaactttga tatttaagat caaaaaagac actttgccct cagttgtgac gggaggatta
    11161 tccacagctg catttcgtat accggataac aaaaaaacac tagaagtaat cgaactttcc
    11221 ggtgttccgc ttgtcggtcc aagtgcaaat acgtcgggaa aaccaagtcc aacgactgca
    11281 gatcatgtat atcatgatct acaaggaaaa attaccggga ttattgatga tggagctacg
    11341 cgaattggtg tagaatccac tgttcttgat ttaagtgatc caacagccat gcctatgatt
    11401 ttacgaccag gtgcagtaac gaaagaacaa atcgaagcag tcatcgaatc tcctgttgct
    11461 attgatcagc atcttgtaaa agaaaatgaa acaccaaaag cccctgggat gaaatacaaa
    11521 cactactcac ccgatacacg tgttctgatg gtcagagatg gcgattggtc aactgcagtt
    11581 caatgggcaa aaaataagaa gatccgtgca ggtgtcatag caagccccga aattgcggat
    11641 caagtgcgga cagatactgc agctgtttat atgtataacg acaactcagt agaagcggcg
    11701 gctaaaggat tgtttgcagg tctaagagga ttagatgaac caacacttgg attagatttg
    11761 atttttgtac aagtgtatcc agaaactgga ttggggaatg cttacatgaa tcgcttgaaa
    11821 aaagcagcag gacaaaatta ttttgaaaaa tgatcaattg gttattgtcg cattctttta
    11881 gtatgataca atgctatcaa gtaaatcttc tatcagtgaa cgaaaaacta agcgtaacta
    11941 atcgtaatag aagagatacg aatatttggc aatttgtttt tgatgggaaa aataaaattg
    12001 taggaaaata aaaaggagct gttgtttgtg gtagattaca aaacgtttga ccctgatctt
    12061 tgggctgcga tcgccaaaga agaagaaaga caagaacata atttggagct gattgcctct
    12121 gaaaactttg tctccgaagc agtgatggct gcacaaggaa gtatcttgac aaataaatac
    12181 gcagaaggtt atccagggca tcgctattat ggtgggtgtg aatttgtcga tatcgttgaa
    12241 aatttagcga ttgaccgtgc aaaagaatta ttcggagcga aatttgcgaa cgtccagcct
    12301 cactccggct ctcaagccaa cacggctgct tatctcgctt tggtagaacc aggggacacg
    12361 atcttaggaa tggatctttc cgcaggcgga catctaacac atggatcacc agtcaacttc
    12421 agtggcaaaa cctatcactt tgttgcttac ggtgttgatc cgacaacaga agttattgat
    12481 tataatgtgg tacgtatttt agctagaaaa catcaaccaa aattgatcgt agcaggtgcc
    12541 agtgcttacg gacgaacgat cgactttgcg aaattcagag aaatcgcaga tgaagtaggc
    12601 gcaaaactga tggtagatat ggcacatatc gcaggattag tagcagcagg acttcatcct
    12661 aatccagttc cttatgcaga tatcacaacg actaccactc ataaaacatt gcgtggccct
    12721 cgaggcggca tgattttgac aaacgatgaa gcattagcaa aaaaaataaa tagtgcggta
    12781 tttcctggta ttcaaggcgg ccctctagag catgtgattg cgggtaaagc agtagcattc
    12841 aaagaagcat tagatcctgc atttaaagaa tatagtgaac aaatcatcgc caatgcaaaa
    12901 gcaatggtca aagttttcaa tcaagcaatt ggaaccagag tcatttcagg ggcgacagat
    12961 aatcatctga tgttgatcga tgttcgcgag ttaggtataa atggaaaaga agcagagagc
    13021 attttggaca gtgtgaatat cactgtaaat aaaaactcga ttccttttga aacactaagt
    13081 ccattcaaaa caagcggtat tcgaatcggc acgccagcaa tcactactcg cgggttcaaa
    13141 gaagaagatg ctgtaaaagt ggctgaacta gttgtcaaag cattacaagc aaaagatgat
    13201 aacgctcaac tagacgaagt caaaacaggt gtacgcgaat taactgaaaa atttccgttg
    13261 cataaaaaat aaaaatttaa attccattag taaacagaaa agttcaatgt tgggcttttc
    13321 tgtttatttt ttgggaaaac ggattctttg acaatatcgg tgatgctctc tagtatatga
    13381 ggtgtaattt tagtcttcac actaaatctc agggaggaaa agtcatgact gatcgtatct
    13441 cgttagaaaa ggaagcagta gcattcagtg atgcaaatgc gcctcatccg cgtatctatg
    13501 aactagcacc ggaagaagga agagttttac tagaagaagt acaagaatca cctgtgaaca
    13561 aatattccgt cgatattgaa gacttgatgg tggatactgg cgaatgggga aaactcaata
    13621 ttcgtctcgt acgaccagaa gggaatatgg ataaattacc agttattttt tatattcatg
    13681 gagcaggctg ggtttttggc agtgctcaaa cccatgataa attgatcaga gaacttgcgg
    13741 ttcgtacgaa ttccgtcgtt gtctttccag aatatagtcg atcaccagaa gcaaaatatc
    13801 caacagcaat tgaacaaaat tatgctgtgt tgcaacagct gaataaatta gccaagtcaa
    13861 aaaatctgga tctcgagaat ctaatcgttg caggagattc agtaggtggt aacatggcta
    13921 cagtcatgac gatcttaaca aaagaacgaa agggcctccc aatatccaag caattgctgt
    13981 attatccagt cacaaacgct gattttgata cagattccta tcatgaattc ggagaaaact
    14041 attttttgac aagagaagga atgatgtggt tttgggacca atatacgacg aatgaagaag
    14101 agcgtgctga aatcacagct tcgcctttga gagcaaatat aaatgaacta aatgatcttc
    14161 cttcagcaat gattttaacg ggagaagcgg atgtattaag agatgaaggt gaggcttatg
    14221 cgcgcaaact tcgtgatgca ggggttcctg ttacacaagt acgcttccaa ggaatcatcc
    14281 atgattttgt catggtaaat gctatggatc agacaaaggc aacgcgtgca gcaatggcat
    14341 tatctacttc ttggatcaag aaaaaagaat aagctttgct tgtccgcagg aaaacttctt
    14401 ttcaaaaacg gattttctta ggaaaaatgg cgagtttgac tagtcaatca cttgattttg
    14461 ttttacaatt aaaaagaaac gacagaacaa aggagagctt aaaaaatggg caaatttcaa
    14521 gtgatcgatc atccattgat tcaacacaaa ctaactatta ttcgggacaa aaactgcgga
    14581 acaaaggttt ttcgtgaagt agtcgatgaa atcgctatgt tgatggcata tgaagtatca
    14641 cgggatatgc cattggaaga catcgtgatc gaaacaccga tcactgaaac aacacaaaaa
    14701 acgttgtctg gtaaaaaagt agcgattatt ccaatcttgc gcgcaggtat tggaatggtt
    14761 gacggtatct tggaattgat tccagctgct aaagtgggac atatcggtct ttatcgagat
    14821 gaagaaacat tggaaccaca tgaatatttc gtcaaacttc cagaagacat tgatgcacgt
    14881 cagttgtttg tagtagatcc aatgttggca acaggcggat cagcaatcat ggcaatcgat
    14941 gcattgaaag aacgtggcgc gtcgaacatt aaatttgttt gtttggtagc agcacctgag
    15001 ggagtaaaag ctttgcaaga agcgcatcct gatattgaca tctatacagc ttctctagat
    15061 gaaaaattga atgaacatgg ttatatcgtt cctggactag gggatgcggg tgaccgtttg
    15121 tttggtacaa aataagtaaa tacgaaaaag ggtgtgacac aacttttgtc acatcctttt
    15181 ttggtcattt ttaacgtttg atgcagaaca gctttttcac agctttcgtt tgcatataaa
    15241 aaaaccatcc caaaaatgca gagatggtca aattcaaatc ttttttagtt ctttgtagtt
    15301 aacgattact acacccttac tttgcgtcat caagttcgca ttttctgcag tttcatcaat
    15361 ctcaacaaca gcggaatttt tcaattgctt tgaaatcgtt ccagtttgcg acttgccgtg
    15421 aattgtgaac attacgtgag tattgatctt gaatttttca ccaatttccg atggtacgat
    15481 agttgtatca aattttccaa aagttgccat tttcataaaa cctgcctttc acatcaatta
    15541 taccacgttt tatgaaaaat atcatgaaat taaactaatt ttccatcgga ctctttacaa
    15601 tcagccaaat agagtatata atttcttttg gataaggcca gcttagctca gttggtagag
    15661 caacgcactc gtaacgcgta ggtcgtaggt tcgatcccta tagctggcat taaaagagaa
    15721 gacagatata tcaaggattt tt
//
LOCUS       DADLIO010000059        15436 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.062, whole genome shotgun sequence.
ACCESSION   DADLIO010000059 DADLIO010000000
VERSION     DADLIO010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15436)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15436)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15436
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.062"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(1017..1358)
                     /locus_tag="JOX41_002105"
     CDS             complement(1017..1358)
                     /locus_tag="JOX41_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAY6449825.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(1358..1588)
                     /locus_tag="JOX41_002106"
     CDS             complement(1358..1588)
                     /locus_tag="JOX41_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAY6449826.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            1875..2213
                     /locus_tag="JOX41_002107"
     CDS             1875..2213
                     /locus_tag="JOX41_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449827.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(2418..2657)
                     /locus_tag="JOX41_002108"
     CDS             complement(2418..2657)
                     /locus_tag="JOX41_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
                     /protein_id="HAY6449828.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(2633..2980)
                     /locus_tag="JOX41_002109"
     CDS             complement(2633..2980)
                     /locus_tag="JOX41_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF159 family protein"
                     /protein_id="HAY6449829.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(3712..4293)
                     /locus_tag="JOX41_002110"
     CDS             complement(3712..4293)
                     /locus_tag="JOX41_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAY6449830.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(4476..5102)
                     /locus_tag="JOX41_002111"
     CDS             complement(4476..5102)
                     /locus_tag="JOX41_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAY6449831.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(5124..6455)
                     /locus_tag="JOX41_002112"
     CDS             complement(5124..6455)
                     /locus_tag="JOX41_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HAY6449832.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(6610..7011)
                     /locus_tag="JOX41_002113"
     CDS             complement(6610..7011)
                     /locus_tag="JOX41_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAY6449833.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(7097..7303)
                     /locus_tag="JOX41_002114"
     CDS             complement(7097..7303)
                     /locus_tag="JOX41_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449834.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(7398..8900)
                     /locus_tag="JOX41_002115"
     CDS             complement(7398..8900)
                     /locus_tag="JOX41_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HAY6449835.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(8918..9373)
                     /gene="argR"
                     /locus_tag="JOX41_002116"
     CDS             complement(8918..9373)
                     /gene="argR"
                     /locus_tag="JOX41_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HAY6449836.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(9471..10088)
                     /locus_tag="JOX41_002117"
     CDS             complement(9471..10088)
                     /locus_tag="JOX41_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449837.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            10309..11682
                     /locus_tag="JOX41_002118"
     CDS             10309..11682
                     /locus_tag="JOX41_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAY6449838.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            11757..12869
                     /locus_tag="JOX41_002119"
     CDS             11757..12869
                     /locus_tag="JOX41_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HAY6449839.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(12941..14578)
                     /locus_tag="JOX41_002120"
     CDS             complement(12941..14578)
                     /locus_tag="JOX41_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HAY6449840.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(14746..15354)
                     /locus_tag="JOX41_002121"
     CDS             complement(14746..15354)
                     /locus_tag="JOX41_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAY6449841.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
BASE COUNT         4274 a         3166 c         2692 g         5304 t
ORIGIN      
        1 taaccaacag caaaaaatac aatgaaaaac aaacttggaa ctaatgtatc attaataaat
       61 gttgaaaaat tcagcaactc attactgtat gattttagca gcccaaccaa catataccct
      121 ataaaagcta ataagatggt taggaatcct ttagaatttt tactcattca tagacacttc
      181 cttaaataac ttttattata gaaggtattg taaataataa tattgacaaa aagtgactca
      241 aaataaaaaa aaccttacat tatactggaa tgaactgtat tgatagtgta cctaaaagct
      301 ctactgacat aagatcgtgt aatcggtaaa gtaattttat taattatacg ggatgtaatc
      361 aattagagaa taaactaatc ataaaaggta cttttacatt cataattgtc gctttgagat
      421 tctactttgg ttcactatct gacccaattg cacattttcg atcattacaa gtattggtgt
      481 cgttagaaca actaaataaa aactagcggt agatttttca gaatctatgc taatttctgt
      541 atggatgttc cagtgatggc aaatttctct tttcattgtt tttcttgtcg catgatatgc
      601 ctttttgtgt tattcagtta aactatagaa attctttcct agacagatct tgatcccaaa
      661 ttttacgttt ttgagcatcg atatagttta aaatgacatt actcatatct aaagagttta
      721 gattttttag gactaaaact gtcagttgtt ctttttcttc tttctgttaa agtattgtcg
      781 cgacttttcg tatacgttaa gatatgtcgt gaaaaaacaa gttttgtgac acaaaaaaac
      841 gaatgacttg aggaaatcac ctcaatcatt cgtttaaaat gctatatatt ctttagttta
      901 agatacggaa attaatgcca tcgaccacac tagtagaatg aacgacattt acttggcctt
      961 tttttaattt cgttatgttt agcatataaa aatattatag agtttactta caatgcttaa
     1021 aacatatact gtataatctg atcaatttta gccatgtctt gcaatggtaa gttttctatt
     1081 tttttgagtt ttcgttcctt aaaatcaaga gattttaatt gtgtaataat tacttgtcct
     1141 tttatatcta gctcttcagg taatgagtaa cgtgtcggta aattctttat agtggaagta
     1201 attggacata tgaccgaaaa cattgtttta cggttaaatt cataacgaga gacgactagt
     1261 cctggtcgtc ttttttgaat ttcttttcct acggagggat caaaatcaat ccatacaata
     1321 tcaccttttt taggaatata aattctttct tctgacacta taaaatttct ctcccttcag
     1381 gagttaaatc ttcccattcg tctttctcat aatactcggc ctcttcccca ccactaaatg
     1441 gatcttcaat ttttggaact aacgtaattg ttccatcatc agaatacaca acgatatatt
     1501 cttggttttc tgaaggtttc tttccgttat cagaaggtaa agttaccact acagaacttc
     1561 cttgtaatct agattttgta acaagcatta tcatcactcc cttaataaaa gtatactata
     1621 taacactaag taacgcaaaa ttcccctttg taaactatct agaaaattgt tttgtttaaa
     1681 gtatatctta ttggatataa atagaaataa attgtagcca gttcattttt tctttaacta
     1741 aaaaaataat ccaagaaaca ttgaacctat ggatccaaaa gctacccaaa tactatagct
     1801 aaccccccgc taccttcaat tttgcagata aaacgctttg ggagaaaatt tcaaagacaa
     1861 caggccatcc tatcatgccc gattataaac aaaaagctgg ctattccttt tgctctgaca
     1921 aatttcaatt gggaaagttc acgaaactag caggtgaaga agtttcaact gttcggatca
     1981 aagaatgccc gcttcaaata gaaacattgg ttcaacgaat ttcaactaga caagactttg
     2041 ctattgtaga acgtgagatc gtagctattt ttgtagaaga agggatttta catgatccaa
     2101 ctcatatcaa tgtggataaa tggcaacctc ttatctataa attcagagaa tatacaactg
     2161 ccaaccagtc gttaactttg aattttagat tccaagaatt caaagagtca taatgataaa
     2221 catcgttagg tataaataaa aaagactcgc agcacgagta aaaaacaaat agaagctata
     2281 cattagaaag gtcgactgtg accctataga tgcagtatat gcagcttatg agcatttctt
     2341 ctgttctctt tgtttttggg atctgtgctg aagtcttttt cgttttttgc cgctctttct
     2401 ttgaaaaatc gattatgtta taccttctcc attactaatt caggcatctg ctgagtaatg
     2461 atttttcgcg caaaagaaat atctgttacc caaggttcga tttgttcttc agtcaagaca
     2521 agcggcattc ggtcatggat tggtgcgact gtgcggttag gttcagtagt cattatgatt
     2581 gattctgcca ttttttcatc ctgatggcta cgataaaaac cgccaatata cactattttt
     2641 tccttatttg aaaacataaa tttgtctttt tcttcattcc actcattggg aaaacacaac
     2701 gattttgcaa aaatggttga tgaaaggtct ttttttcttc tactgtctct gcacgggcat
     2761 taatcatcaa ttgtcctttt ttaaatccgg taaatcccca cttcatgatt tccggagtga
     2821 ggatgttttc ttcctctttt cttaacgtca caacaagatt tgacggaaaa acttctccag
     2881 ctgctaattc tgctgcctgc ttcggttgtt tcgtctgggc ttctcgataa taattctgaa
     2941 ggagctctga ctctagatca aaaaaataac gaccacacat cctaatccct cccaatcttt
     3001 ttttctatca tacactgcaa caagaagttc gcaccaacaa aacgctttca atttttgtag
     3061 aactaaaaaa gttgtgacaa gtgacaaact ctccagtgaa tggtattctc ctgccaactc
     3121 ctcggtcaca agtcacaata ttcaacaaac atgagaagct gctttttgaa attgttcctt
     3181 gtgactcgga gtgaaacggc aggcttacga cctctgggta aacggtgttc aaaagccagt
     3241 ttctcggtat taagccaaat ttatgcaaaa atgtagaaag ctattttcac aaaatttttc
     3301 ttaatactcg aaactaagcg actttttcac aacctcttcc ttaaacggtg ttcaaaagct
     3361 tgcatctgcg gtaataagcc caaccaaacg aaaaatatga gcagctattt ttatttggct
     3421 gttcttatta cttgatgcag ggcagctttt tcacaacctc tccactaaac ggtgttcaat
     3481 cagctaacct tcggtattag ctcaaaaaac ggcaaaatat gaggaactat tttgccgttt
     3541 gtttctctaa tactcaggtc aaagcgctga tttcacaacc tctaatacac ggtgttccag
     3601 aagtagcttc ttcgaaaaat aagccgaaat ttcacaaaaa tttgagaagc aattttcgta
     3661 aattccttct tatttcttga agctgaccac ttctgtcaca acctctaatt attaaagaac
     3721 cttttgcgaa gttaacaatc tttctttgat caattgaaaa ttctgcctaa gtagtgatag
     3781 atcctgtgtg actttcaaca ataagatact tccctggatt tcagcaatca acgctttggc
     3841 ttgacggtct gcttcttcat cggacagttt ttcttcagaa agtgccagga tattttgttt
     3901 cgtatacttg acccattgat tgactaattc tagtagcaac agacggtatt cttcatccac
     3961 tgtactcaac tcaataatca aattacctac aggacagcca tgataagtga tctgtgtctc
     4021 atgatcagcg aaaatccagt ccaacatttc ttctaatgct tcttctggct gttttccagc
     4081 atttaagatg tcttcgaaca attctgtctg ccatacgtcc atatgcgcat ggatcaccgc
     4141 tagacaaact tctttttttg aagaaaagta ataataaaat tgaccttttc ctgtatcaga
     4201 agctgctaga atatctcgga ttgacgtttc atgatagcct tttttataaa taagatcttt
     4261 ggtcgcttcc aagatctttt cctttgtttt caatgatatt ctcctttttc atttctcata
     4321 gtcctatatt atacagtaaa ttcatcattt tttcttctta atcgtttaaa aaagactgtg
     4381 ccaaattatc tgacacagcc ctcactataa aactgttctc atatagctag atgttcattg
     4441 attcaagaac tgcgaggaca aaagcaattc ctatcttatg atagttgctc taatacttcc
     4501 tctgttgtca tcacttgatc tgcaataaag ccaaagttcg tcaacgctgc atccattgct
     4561 tcttggccag gagcaccaat tgcatctgtc gctaccacaa cattgaatcc actctctacc
     4621 aattcacgca tatgggaatc gctacacaag tttccgttca ttccaccaag aattactgtg
     4681 tcgattccat tttttctcaa ttggagcgcc aaatcattgc tttctggtcc aaagatttta
     4741 tgaggagagc tgatgatcgt attttcatcc aaataaggtt tcaattcttc gataaaatcg
     4801 gctcctgaac cttcttccac tgattcatat tgactttttc tagcaaacat ctgctgctca
     4861 agcatcatat gttctcctgc accgccaaat tgccatttat ggtcatgtgg gtaaaaataa
     4921 tgaggagaaa taaagagttt gtatcctttt tcttttgctt gttttaccat ttcaatcata
     4981 ttttcgatcg tattgtattt ttctaagata tcttttgtca aaccaaagcc accgcctgct
     5041 ggtttcaaga actcgacttg cgggtcagtg agaactactg ctgtattttt attattgaac
     5101 atggtggatt ctccattcgt tatttatttt aatacatcat ttagagcttc actcattgtc
     5161 ggatgagaat agatttgatc tctcaataac gtataaggaa gttttccatt catagctagc
     5221 gaaatcaagt tgatgacttc atgagaatct tccgcataga tacttgcccc tagaatcaag
     5281 tcagtttcag ggtcgactaa aactttgaat acacctttag gatcttctaa tacttgtgct
     5341 ttagggacac cgcttgtcat atacttgaat aatttgtaat tgacgccttg tgctttggct
     5401 tgtttttctg ttaaacctac attggataaa gtcggagtga taaatacact gtaaggcaca
     5461 gctttccggt tattcgttgt tcgtttattc tcgcccttca actgatccat aatgattcga
     5521 taatcatcta gagagatata agtgaactgc aatccgcctt tgacgtctcc aatcgcccaa
     5581 atgttgtctg catctgtacg aaggtattca tccacagcga ttgctccgcg atctgttagt
     5641 ttaacatctg tattttctaa tccaagtgat gctgtacttg gttttcttcc agttgcagcc
     5701 aaaacttttg acgcttggat tgttacttct tggccatctt ctgtaaaggt gacggcagct
     5761 gttgattctt ggtctgctac ttgatctaca gatacaccta gatggaattc gattcccgca
     5821 tttgtcatgt cttctaaaat catttgcgcg atatcttcat cttcacgtgg aagaaattca
     5881 gaatgggcat caagaacgac aactttagat ccgtattcat tgaacattga tgcaaattcc
     5941 aagccaatat atccagcccc gatgatcact aatttttccg gtaattgttc ctgatccatc
     6001 gcttgcgtag aatcaatcaa gtagcgactt gtattcaatc ctttgattgg taaaatgatt
     6061 ggttcagaac cagtattgat gaaaatccgt tcgccttcaa caatcacttt ttcaccatta
     6121 ttcgtcactt cgatttgatg gttagaaaga aaacgtgctg taccgtccat cactgtccca
     6181 gttgcctcat cgctgatcat atgataattt ttggcgcgaa gcatgcccgt caatttttct
     6241 ttccgagcaa cagcctctgt aaagtcgatt cctctttctc cattgaaaat caatgattta
     6301 gaaggaatac agccgatgtt gatacatgtt ccgccataca tacgtgttga cttttcaacg
     6361 actaaaaccg attcaccttt tgaagctaac gccttcgcta aagtcttacc gccctttcca
     6421 aaaccgatca caatattttg atatttttcc atcatttttc cctcgcttct tttttaccta
     6481 ccgattggta caaaaatatg ataaccgata attgtctatt ctccaaatca tctgctttat
     6541 ttgtcaaaaa aaaccagaca aaaagcggtc ctttcacgtt tttagtctgg ttcgatttcc
     6601 tttattcttc taaacaatcg ttacttctac atcgatattt cctctagttg ctttggagta
     6661 agggcagaat tcatgcgcat cttctgcaat tttttgggct tcttcttcgc tgatgccatc
     6721 gatatgcact tctaatacta caccgatctg atagccgcca tcatctaaat tataaagaga
     6781 gacacgtgct tttactgtgg actctgctgt cattcctgct tctttgatca tatgttgtac
     6841 cgccccattg aaacaagaag cataacctgc tgcaaataat tgttctggat ttgttccttc
     6901 tgcatggatt cctggaggag tgattttcat atgcatcgag ccatttggtg cctcgacttc
     6961 tccattgcgc ccgccatggt tgatcattgc tgtttcgtat gcttttttca ttgtactgct
     7021 cctttcgatt gaccatttgc tacttggcta taattatagt gtatgacaag taaggcgctt
     7081 tctacaaaaa ttctgcttat tcgaatacca gaatgccgtc ttctactatt tttccaaaaa
     7141 acaaaaaaat actactcgtg aacaacagcg tcatatttgt tccaaaataa atagcaatct
     7201 tttctacata atcttttata tgattgattt taagatacat atataccaga aagttgaccc
     7261 cataaaccaa tactgttaaa aaaataacca tattcgttac cattttttcc tccttttgct
     7321 ggtctcccta ccagcactcg atttaaccat accacttttt ttgccgtcca agcaactagc
     7381 ctttcaaaaa gactggttta ttctgctgtt aatgattcaa gatcagaaaa atgtccgaat
     7441 aattttgcta attttactaa cgccaacttg ttctttccga attcatcatt ttctatctgt
     7501 aatactagta acggctcatg taagcttaaa cggatcaaaa accagccgtt tccgtatggc
     7561 tcttctagat catatcgaat accttcttca ttttccgggt cgaagttcat ccctttttct
     7621 tcttccaaca gtcgcttcat ttcttctaat atcttgtttc cttgttcgcg tggttcatcg
     7681 ctgaacaatt ttaatcggat ttcttgtact tctacgggct gtttcaactc tttgatttgt
     7741 tcatctaatg tgataccttt tctttttaat tctggcaaaa gcatcaggat ctttgcgatg
     7801 acatatgcac catcatccag aaaatagttt tccttgaatg cagcgtgtcc gcttgtttcg
     7861 atggctagct gtgtatcttt cccaagacgg ttaagttcta atgctttatt gattacattt
     7921 cgatagccgg aaatataacg aacttggatg cctccttttt cttcaatgaa tctttgtaga
     7981 tgagaagaag taggggaatt cgtcacgatt cttgttcctg gatgctcttt taatacgatt
     8041 gtacttaata ctgcgatcaa attatttcga ttgatcactg ttccagaagc actgacaact
     8101 gcagaacgat ccacatctgt atcgaaaatg atcccaagat ctgcttcatt tgctaaaaca
     8161 gcctgcttga tactttccat cgcttcttta ttatcaggat ttgggatatg attaggaaat
     8221 cggccatctg gttccaaaaa ttgggaacct gttgaatccg cacctaagct attcaatact
     8281 ttttcagcaa agaatccacc agcaccattt ccggcatcaa caatgatttt ccaaccattt
     8341 agtggtttgc tttctagtgt tccaatcccc tttttaattt ttgtgactaa atcttgcgca
     8401 taaggtgtca aaaggtctgc tttttctacg cttccagttt gttcgctttt tattttttgc
     8461 tgctgtgata ggataaaagc aatatcttct ttttctgctc ctccttctga ggtaaagaat
     8521 tttattccat tataataata gggaagatgg ctagcagtca gcataaccgc agcatcgcac
     8581 gagaactgtt caaattgagt ggacataaac atagcaggcg tagtagctaa ttcgaaatcg
     8641 atgacatgta tcccttgttc tttcagactt tggatcaacg cctctttcag tgctggtccg
     8701 cttatcctac tgtcatgacc aatcccaatc gtccattttt tatttggatc ggttgatttc
     8761 ttctttttct ttatccagtt tgctagtccc cagccgatct tttttaccat gtctgtcgtc
     8821 aagtttactt catatccttc aactggtaat gcgattcctc gaatatccga tccattttgc
     8881 agcgctttca tatctttcat ataaaagtcc tcctcattta ttccctcatt ttttccagct
     8941 tttctgcaaa tcgctgtgct tcttcttctg agcggcaaat aataatgaat gtatctacac
     9001 cggccatcgt tccgacaact tcagggtaag ccacttcatc tagccaattc gttaccacat
     9061 cggcaccatt tcgttcagtc aatacgataa ccatgaactg aacagactgg atacgcaaaa
     9121 cctcgcgtct aattgctgta cgcaaacgtt cttcatttaa agaaacagat ggctggttaa
     9181 ataatgtata gcgtactatt ttgttttcat tttgactttt tactaacttc atttctcgaa
     9241 tgtctcgaga aatcgttgct tgagtcacat cggcgcctgc ttcatgcagc cgcgcaagca
     9301 gctcttcctg tgtcccaata ggttgttctg taatgatctg gcggatcagt gcttgtcgct
     9361 gtttcttttt catattagac acctctcaat gttgattata gcaaaagata agtaatattt
     9421 cttcatattt tggtattttt tacttttatt ttttgttttc attcaggttg ctaacctttt
     9481 tctattttaa cacgcaaaat cgtcttcatt ttttcaggtg ctgattttct tggatcgctg
     9541 atgtaaatct ctttgtgttc tttagaagct ctttcatagc cttcttttgc gatgaatgct
     9601 tctaatttct caaacgttgc tggttcttcg gcatagggcc cgacgtgtaa gatttgggca
     9661 caaagacctt cttccatctt tttgaatact acttgttctt tcaagtcttc cggaagtttg
     9721 ctagaacgct gaatggcttc ttgtgctatc gcttctgtaa caaagtcagg ctgtcggatc
     9781 atcaattgat aagaaaaatg ttcttttttc atcactggtt catgcaaata cttttcttgc
     9841 agtccccatt gtccttccag tggatagaca gtatacatct gataatcagg aatcagccaa
     9901 ttttttttag gcgacatgcg tattgcatag ctgactgcat atagacaggc tactcttcgt
     9961 ttaaagtctt cctgattcgg gtcgccgatc cctctgatgc taaagaatga ttttttagga
    10021 acctctagta tttgcgggct ttttttcata ctatagctct tgtctttacg ccattcaatt
    10081 ttttccattt ttcttcctcc gcgaaattcc atttagttat ttattatcat acctcttttt
    10141 gagtgacttg gctaatcgtg ttgacactat ttttcagttt gtgctagaat aagtgaagta
    10201 aataaatcgt acagataaca cgtttcggcg tgtcgagaga gaggcggttt ctatttttat
    10261 aatagaaatc actctctttt tttacgaaat tttttagagg tgatgtaaat gacaaaacaa
    10321 aaacagctgc ttttagtacc tgcagtaatt gcaacaggga tgatgtcttt tgcgggcgta
    10381 ttgatcgaga cggccatgaa tgtaactttc ccaactctta tcagacagtt tgatttaacg
    10441 actgcacaag tccaatgggt aacaacgatt tatcttttga tgatttcgat cattgttccg
    10501 ctgtctactt atttgaatcg caattttagt ctcaaaaaac tctttttagc ttcaaatctg
    10561 cttttcttgg caggtataat gatcgatttc ttctctccta ccttcatggt cctattgttt
    10621 ggtcgattgc tccaaggtgc agcgacaggt atcgctcttc cgttgatgtt ccatattatc
    10681 ttgacatttg cccccctcaa tcgacgaggc gcgatgatgg gtgtcggtac tttgacaacg
    10741 gccattgctc cagcaattgg ccccacttat ggaggcatta tgacttcaca ttttacatgg
    10801 aatcatatct tcctgtttct tgtgcccgtt ttgtttcttt ctttgattat cggctggttt
    10861 gctattcccg agatggcagt acaaaaaagt ggttatttgg attggataag cgttttagga
    10921 atttgtcttt tgtttagtgg aagtctaaca tttttgagta cgttgggaac agtttccagc
    10981 tggattgctt taatcatcgg cggtattggc tggttccttt tttactatcg aagtaaaaaa
    11041 gtggagcatc cactgatccg actgtctatt ctttcaaata aaacattccg cttgtttttg
    11101 attggcttct tagtttatca gtttttatta cttggtgtat cttttgtctt gccgaatttc
    11161 cttcagatcg ttcaaggaag tagtcctttt gtcgctggat tagcgatgct tcccggcgca
    11221 gcggttggtg ctttgctttc tcctttttcc gggaaaatgc tggatcaata tggtccgaag
    11281 aagccaattt ttgctgggct gattctttct ttgattggtt ggctagcatt attcctactc
    11341 ataggacacg cttcagtggg tgtattgatt gcttgtcatg tgttttatat gatcggtatc
    11401 ggattatctt acagcaatat gatgaccacc ggaatgaatg cactgaatga agaactacaa
    11461 ggagacggga acgcaatgtt caataccttg cagcagtttt ctggcgctgt ggctacttca
    11521 ttagtagcgg tcattatcaa ttacgtccag catcatactt cccataacta tgaagtgtct
    11581 actacattag gatcaaaagc agcattaggc gtcttgttgc tgttgcttct cgtaagcttt
    11641 gctcgattcg cctattatct gttctttgct aaaaaagcgt agattccata tacggcaggt
    11701 gttgcatctg ccgttttttt gtgtgaaaat ggttgtttgt aaaaggaggc ttttttatgg
    11761 aaaaaattgc cattatcggt ggcgggatca ttggtatgac cctagccagt tacttagata
    11821 catcaaaatt caatgttgct ttatttgatg aagggacagg acaggcaact aaagctagcg
    11881 ctgggattat ctccccttgg ttgtcgaaac gcagaaacaa acaatggtat cgtctggcta
    11941 aagacggcgc tgcttttttc cctaaactta taaaagattt ccaacttgat caaacgattt
    12001 acgcacaatc agggacactt ttgcttcgac ctgaaaaaga tttagctgaa ttggctgttc
    12061 ttgccgagaa acgaaaagaa gaagcgccag aaattggaaa catcgaatgg ctttcacctg
    12121 aacagacatc tcaagcactt ccgttattga aaccagcagt ttcactgcgt atcagtggtg
    12181 gtggtcgtct ggatggaaaa gcatatttag aacatcttgg tcagcgttta gcacaaaaac
    12241 aaatggagca gatccaggca aaagtcactt tgcataagaa gagcgattct tggctcatca
    12301 agggaccgtt tggagaatac acagctgatc gtgtaatttt gacacctggc ccggcactta
    12361 agcctttatt acaagaatta ggctatgctg cagatatacg tccgcaaaaa gggcagctct
    12421 tagcatttca gacatcttat aagatgagtc aagactggcc tgttgctatg cttgacggag
    12481 aagctgattt cattcctttc atggatggaa agatcctttt aggtgctacc catgaaaacg
    12541 atcaaggctg ggatttggct cctactagcg aagcttataa gggattgact aagagtacag
    12601 aacagttctt gactgatcca gatcagataa aaaactggcc atacgagttc cgtgtaggta
    12661 cccgtgctta tacgtcagat ttttccccat ttttcggcgt actgccagat gatccaagct
    12721 tactggctgc tagcggtcta ggctcttctg gcttgaccac aggtccttat atcggctatc
    12781 tattagccaa cttcttaaat actggtcatt ggcctacgga agattatcaa aaggacatct
    12841 ccacctatat tacgaaaaat ccatcataga aaaacagctt tttcaagtaa ggatcccgag
    12901 cgatattgcg catggattac ttcttgaaaa agctgttatt ttagttcaat ttctgaatca
    12961 aattctccaa actttctttt gcttcatctg gcaagagatc ttttcctatc tgagcttcaa
    13021 tgaatcgtaa acgaatatca agtcgttgtt tcaccagatt tttataggac gtatcctcaa
    13081 aagaaacagg aaaatctggt ataggtaaat agtggatgtc ttcaaatgga ccaaacgact
    13141 tgaattctgc cgtttgttgc acgattcttt caacgattga caatgtcgtt tcaggtttga
    13201 tttttttatc atcgaaatat ccagtattca ggacatagca ggctgtttgc tgtttcaaaa
    13261 acaactctcg aaaagcttga tagtcttccc taagaggata gacacggaaa ggattagcaa
    13321 atggttcaat gactagctca tctagctgtc tttttgtagt gatattttcc gcgtctgatc
    13381 gttttgttgc taatgttgca ccaaaagacg ctgctaaaac tgggtcattg atcttgataa
    13441 ttggcggaag cgaatcatct ttcatgatcc aaaaaacagc atcgatcttt tcgctaagat
    13501 gatcgactcg gtcgggtgtc gcataacgtg atttgactgt ccgcccattt ccgtttcgta
    13561 tatctcctgt tactaggact ttttctcctt tacttgtaca tgtcacgccc acattctgac
    13621 aagtaaggaa agaagaaatg gccggatcat cagacggata gtcttgtgtt ttatcaaagt
    13681 aagaaggttc caaggcagta gcaaaaccat tttttcgaga aataacgaaa gcatcgtcat
    13741 gcaagatcga aacagagtga ccttccgtat gttttgctaa ggtaatcgtt gattttccag
    13801 aaccggacaa cccaaataca gccatcgtat aggtctggtc attactagca tattgtttca
    13861 tcccaccgtg gcaggcaata aagccattgc gatttcccaa tgcccaagca agcgtcaaag
    13921 tcgctttttt taattctcca aagtaacgta atcctagcac agccgctgta ttatggagag
    13981 catcaaacaa aatgagtcca tttggaaatg tttcatgtgt ccattcggga tcacaaaaga
    14041 tataaagatc tccctcatca aaggaaacag acttttgata agtctctaag atcttcgaat
    14101 tcgctggctg aaaattcagc aaataagaat acaaattgtt ctcaaatcct tctggaatca
    14161 gcaaatgact ttgcacagaa aattcttcag ataggccaac gattactttt gtatggtaaa
    14221 actggcgctt gcgactttga tacacagctt ctcttaaaat tttctcgtat ttgctttgtt
    14281 ccttgtctaa gtcctcaaag atccgccgag cacttgctgt tcttcccaca atgcttccat
    14341 cattgaatac tagtgtccta acatcagctg gtaaatctag ttcttcagca tgtgagattg
    14401 ttaaatctgt gatgatcgtt cctggactcc cttttgctag ttgataagct gtcttcctat
    14461 caaaaacttc atgaacatta ttaccgtaaa atgtcgtttc tacaatcgat cgaatactgg
    14521 ataacagtgg atttccactt gtgatttcgt ttaattcgag actctctttt gtactcatgg
    14581 ctcctcctca ttccctaaac aaaaaaacgt tttctttatt atacattatt cgagttttta
    14641 tttgtactgc tgcgctgtgg gaagcaaacg agttattttt cacacaaaaa aaccgagaac
    14701 ttgaataaac aagtttctcg gtttcatcat tttcctttta tcggcttagt accagccgtt
    14761 tgctaaccag aatgttttag cagcatccca tgaaccataa cgagatgtta catattgttc
    14821 tgctacacgt tcttgattgg cagctgaata gtcgccgttt aagtatgaag catctaattg
    14881 ataacggccg atgtaacgtc cgttagtagc tgtgtatgaa ccgcctgatt ctttttgtgc
    14941 gatccattct tttgcagagc ttgaagttgg cgctgttgca gcagctgggg cagcaggagc
    15001 tacttcaact gtttcaacag gtgcaacgta tgtatgttct tgcgttgctg tttcagttgt
    15061 agatgctgta ttttctgttg ttttgttttc tgttgttgct gaagaatcat ttgaagttgg
    15121 gattgttaat tgttcaccaa cataaatgcg gttgatgttt gcgatcgaat ttttttcagc
    15181 aattgcatcg atcattgagt tgtctcctgc aaatttttgt gagatcttag ataatgaatc
    15241 acctgatttt actgtataaa cttcatcagc gtgagcattt gtagttccta caaacattgc
    15301 agtagcacca gcagcaaaag ttgtacctaa aacaattttc ttaaatgaat tcatattaaa
    15361 ctcctttttt tctccgtttt ttattctttc gacgctatta actttatcat ttagaaatat
    15421 ttcataggta aaagaa
//
LOCUS       DADLIO010000060        15314 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.063, whole genome shotgun sequence.
ACCESSION   DADLIO010000060 DADLIO010000000
VERSION     DADLIO010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15314
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.063"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            278..787
                     /locus_tag="JOX41_002122"
     CDS             278..787
                     /locus_tag="JOX41_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAY6449842.1"
                     /translation="MVQGIERGVYVVDKIQFNQVIEEFIKVNNLMTHIQKRPIRITND
                     LKLSTSMIHLIDVIGNYPETSITELADRLGVTKGAVSQQIPTLEKMNLISISQKKGNK
                     KTKLVSLTKYGRKVYESHNYLHEELYSSINEALESFSPDQISTIKQILEKVSYTINEY
                     QVSLTRKED"
     gene            880..2042
                     /locus_tag="JOX41_002123"
     CDS             join(880..1156,1156..2042)
                     /locus_tag="JOX41_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAY6449843.1"
                     /translation="MSRRQRRTYSKEFKQQVVDLYLAGKPRAEIIRDYELTTSAFDKW
                     VKQAQTTGSFQEKDNLTPEQVELIALRKKNKQLEMENDILKQAALILGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
     gene            2322..3302
                     /locus_tag="JOX41_002124"
     CDS             2322..3302
                     /locus_tag="JOX41_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAY6449844.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLPVKLIKKNTA"
     gene            3424..4842
                     /locus_tag="JOX41_002125"
     CDS             3424..4842
                     /locus_tag="JOX41_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HAY6449845.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            4913..6382
                     /locus_tag="JOX41_002126"
     CDS             4913..6382
                     /locus_tag="JOX41_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAY6449846.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            6392..6859
                     /locus_tag="JOX41_002127"
     CDS             6392..6859
                     /locus_tag="JOX41_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAY6449847.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            6895..7767
                     /locus_tag="JOX41_002128"
     CDS             6895..7767
                     /locus_tag="JOX41_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAY6449848.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFITSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            7849..10383
                     /locus_tag="JOX41_002129"
     CDS             7849..10383
                     /locus_tag="JOX41_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAY6449849.1"
                     /translation="MKKKMKDEVLEYIKNNLKYYDFSAQDIAMKFCIKRNVASHYLNQ
                     LFSDGKLLKNDSVRPVMFKYNQQKPKDCFSKFIGADISLKSTIDKCKATVMYPPNGLP
                     LIIKGNSGVGKSFLASLIYQYALDRKVIHNDAKFVVVNCADYANNPELLSAVLFGYKK
                     GAFTGAEKDTAGMLSSANGGYLFLDEVHNLSAENQEKLFLLMDSQKYRKLGESVQWEY
                     ANVRLILATTEDKNTSLLATFRRRIPAEITLPDYNNRSTSEKIQLLFEFLKDEAITID
                     SKIFCSIELFTDLLSKTFEGNVGELRNEIKLLCAEGYLGNKRKSSIYLGDKLDSGFWI
                     DPEISIDLKKMFLKSLSEIDLIELFQNHISIEESMSQLRDRILKECAGSSEYNYLESD
                     EFIALRNYVVNKISPIIDSTGLCLLDEFLADISLFIMFIDVIEETSRNFLLSKFRKFR
                     MKNDKQKLLANEIWSSLEVEESKQELLLKWILFLVKKFYVKIPETHCLIVMHGKITAS
                     AIARETNKLLNTYVYEAFDMPIEGETSDLINLINNFCKSIDTTNGLILLVDMGSLEQM
                     YEKIESNVIGDLVILNNVSTALAIECGIQVCQKKPISHFYQMDFDSFQVKVQYYKGLS
                     QKKNVIVSCLSGEGISEKVKDILKRYLDNQVEILIFDFNALKKIAKEKDTMIFKNTIC
                     VLSTTEFYIQGIDCLNLENLINGNQTLEKLNKYMDSDSCEFCLNELVKLFTIEGASTK
                     LRFLDSKKVFNEIEKVLYLYEKYYDVKIPSFLRINLFLHLSGMIERIMIGDGITNEHL
                     KEGAQLFDTFLNVSKDFFSEIKDIYCIEIPKGEYELIYTIFEQTIF"
     gene            10539..11312
                     /locus_tag="JOX41_002130"
     CDS             10539..11312
                     /locus_tag="JOX41_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAY6449850.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
     gene            11305..12096
                     /locus_tag="JOX41_002131"
     CDS             11305..12096
                     /locus_tag="JOX41_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAY6449851.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            12106..12597
                     /locus_tag="JOX41_002132"
     CDS             12106..12597
                     /locus_tag="JOX41_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAY6449852.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            12615..13025
                     /locus_tag="JOX41_002133"
     CDS             12615..13025
                     /locus_tag="JOX41_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAY6449853.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            13029..14429
                     /locus_tag="JOX41_002134"
     CDS             13029..14429
                     /locus_tag="JOX41_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HAY6449854.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIENFKEITPFSSFKLEKEFGKKERVIVP
                     KIEDYFLFETTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPNYPWPQ
                     MFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMTVTEGA
                     IKVDKLDYSINYECGF"
     gene            14452..14826
                     /locus_tag="JOX41_002135"
     CDS             14452..14826
                     /locus_tag="JOX41_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAY6449855.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYESLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
BASE COUNT         5315 a         2156 c         3060 g         4783 t
ORIGIN      
        1 ttttttattt gtctcgctta attatacaaa cggcgtgata aaaaacgaga aatgaattat
       61 aggtttagac ctttatcatt tctcgtttta ttttattgta tcaaggctct atcataagtg
      121 gtaaaatcta cttttaaatc acatgtaatc attgataagt ccagtgtttt agcggataat
      181 cagcttttta tttatttttt cttataaatt tgataaatag aaattagtat agccctaaac
      241 aaattatttg tgttttattg tttagggcta tactatattg gtacaaggaa tagaaagagg
      301 tgtttatgtg gttgataaaa ttcagtttaa tcaagttata gaagaattca tcaaagtaaa
      361 taatttaatg acccatattc aaaaacgacc aatcagaata actaatgatc taaaactcag
      421 tacgagtatg attcatttga ttgatgtgat tggaaattat cctgaaacta gtattacgga
      481 attagctgat cgattaggcg ttaccaaagg agctgtatcc caacagattc ccactttaga
      541 gaaaatgaat cttataagca tttctcaaaa aaaaggaaat aagaaaacta aacttgtatc
      601 gttaacaaaa tatggtcgaa aggtgtacga atcacataat tatttacatg aagagcttta
      661 tagctcaata aatgaagcgt tagaatcatt ctcaccagac caaatttcaa ccattaaaca
      721 gattctagaa aaagtatctt atacaatcaa tgaatatcaa gtaagtctga caagaaagga
      781 agattgacat gaaaaaaatg atttttgaat cggctacact agactagaca gaaaaaataa
      841 ggtgtgtaaa ataaatgaaa acacactgga ggaattttta tgtcaagacg tcaacgtaga
      901 acctattcaa aagaattcaa acaacaagtc gtcgatcttt atctcgcagg aaagccccga
      961 gctgaaatca ttcgagatta tgagctgact acctcggcct ttgataagtg ggtcaagcaa
     1021 gcgcaaacta ctggctcgtt tcaggaaaaa gataacttga cccctgaaca agtagaacta
     1081 attgcattac gaaagaaaaa taaacagctt gaaatggaga atgacatttt aaagcaagcg
     1141 gcgctgatat tgggacgaaa agacaagtaa ttgataccaa taagcacaaa tactcaatat
     1201 cagcgatgtg taaagtgtta aacatctctt gccaaaccta ttattatcaa gccaaaccag
     1261 ttgaagatga atcagaactg gaagaactcg ttcaagaaga atttattcgc aatcgaaaag
     1321 cttatggtac caggaagctg aagcagtgct tggccaatct aggtcttcaa gtgagtcaac
     1381 gcagaatcgg ccgtatgatg aaacagcgtg gcttgcgttc aacatacaca ttggctcatt
     1441 tcaaattcca ttcttctact tgtaacgaag ccaagaccgc caatattcta gacggaacct
     1501 tcctacagga aaagtcatta gaagcgattg taaccgacct tacctatgtt cgtgttggga
     1561 agaaatggca gtatatctgc ctgattcttg atttgtttaa tcgagaaatc atcggctatt
     1621 catgcgggga gaagaaagat gcgacgttag tcaaggaagc ttttgcaaag attccgtact
     1681 cgttgaataa tgtacaactt tttcacacgg atcgtggaaa agaattcgat aaccagacga
     1741 ttgacgaaat tttatgggcc tttaatatca cgcgttcctt aagcaaaaaa ggctgcccct
     1801 atgataacgc cgttgcagaa tccacctata aatctgtcaa agtagaattc gttcatcaat
     1861 accgctttga gacattggct aatttgcgat tagagctatt tgattacgtc cattggtgga
     1921 ataccatccg gctgcacggc acgttaggct atgagacacc gatcagtttt cgacagcaga
     1981 gattggcgca gcgaatcctt gataatgagc tcggatgtga taccggtggc gaggcacctt
     2041 aattatttga atgagcttct gccttagaga atcagattcg aggaggctcg ttgtcaaggg
     2101 cagtcggaac accagcagca agcttacgca ataccttata atttttgtca aaaaaagtgt
     2161 tgccattcca catatatctt taaacagcta ttgccagata aaaataaatg atattatata
     2221 tataaatact tatccgaaaa ggggaatgag agagtcaagg ttcttggaat gtcgaatagt
     2281 cgagtaggta gattttctat ctacaacctt gttgtttaaa aatgaaaaaa attggaatta
     2341 gagaagttgc gaaagaggca aatgtttctc ctacgactgt gtcgagggta ttgaatgatc
     2401 gtggatattt gagtgaggaa acaaaaagaa aagtttttga tgccatgaaa aaattagaat
     2461 actatcctaa tgaactggcg agagcacttt ttaaaaacga aacatatacc gtaggtttga
     2521 tttttcctac aattactaat ccatttcacg ctgagttaat tcaagatatc gagttcgagc
     2581 tttccagcag gggatataaa gtgttgctgt gcaatagctt aaacaatcca acaaaagaaa
     2641 aagagtactt gacgatgttg agaaagaatc aggttgatgg aattatagta ggaacgcaca
     2701 ataaagatat tgcggattat gatattccag ggctacctat tgtagcgatt gatagaagtc
     2761 ttggtgaaaa tacagttaca gtatcttgtg ataattacag gggtggggaa ttagctactc
     2821 aactacttgt aaatcatggc tgtcagaata tactgtgtat tcggggagat agtaagataa
     2881 agctacccgc gaatagtagg actttagcat ataaagatgt tttgaataaa ttcatgctgg
     2941 aaccgttagt cctagaagta ccatttgtaa aagaaatcaa tgaaaaaaat gaaataatta
     3001 agacatatct ggaaactcat ccaaatattg acggggtttt tgcaggagat gatttattgg
     3061 cttctttggc gattaacaac ttaggaagtt cgggcaaaag agttccaaaa gaggttaaag
     3121 tgattggatt tgatggagct caacaaacat tgatttataa tccagaatta tcaactattc
     3181 aacagcctat agatcaaata tctaaagtag cagtaaaaaa attattgaat atgattaagg
     3241 gcgaaaagga gacggatgaa ctttcacttc cagtaaagct cataaaaaaa aatacagcat
     3301 aagttaaatc ggcgaaaaat tccttcgtcg atttaaaaat atttttatga aacgggttga
     3361 catatgaaac gggttgacat atattagttg tgaagataaa aaccttttca ctggaggaag
     3421 aaaatggaga aattattaat taaaagcaat aatcatcaac tttactacca acctaaggat
     3481 gtttgggtcg gagatgttat gccttacggg aaagaaggaa aattctttat ttatcatcaa
     3541 cgtgatacta gaaatccagt tccttttgga gaaccgtttg gctgggcttt agcaactacg
     3601 aaagattttg ttcattttga agactttggg gaatctcttt taagagggga tgacaatgag
     3661 agagaccagt ttatctacgc tggttctgta tttgaggcaa atggaaaggt tcacgcattt
     3721 tatacagggt ataatcgtga attcttagcg cagggaaaga catctcaagt gttgcttcat
     3781 gctgagagtg atgattttgt tcattgggaa aaatcagaaa cagcattgga gttagaacca
     3841 caagaagggt atgatattcg aaactggaga gatccatttg tcgtttggga tgatgaaaaa
     3901 gaagaatatt tgctaatttt aggggcgcga aagggtcagg ataaacatct acaaaccgga
     3961 cgtttagtgg aatttacatc aaaagattta actaattggg aattcaaagg tgatttttgg
     4021 gctccgggat tgtataccat gtttgaaatg ccagaacttt tcaagattgg tgactggtgg
     4081 tatcttgtct attcagaata ctcagatgga aataaaatac tctatcgaat gagtcaaagt
     4141 ttggaaggtc cttggattaa gcctaaagat gaagcttttg atggacgggc ttattatgca
     4201 ggtagaacag cttatgatgg aaaacgtcga gtcctatttg gatgggtacc aacaaaagat
     4261 caagaaaatg ataaaaacaa ttatttatgg ggaggtactt tggttcctca tgaagtctat
     4321 caaaaagagg atttttcact tggggtaaaa cccatagacg aagtgtggaa tgcattcata
     4381 aatttacatg atattgccga tgtagagata gaaacagcag acacaagaga agaagtaacg
     4441 cttgtcaaaa atagtggaac tttgtttaat ttagaaacaa caatttcatt tgatgagaat
     4501 cttagtgact tttcactgag attatataaa aaccttgaga cagatgaatc ttacgaatat
     4561 cgcttcaatt tagatgaggg gcgtcttaca tttgataaaa acccttgtta cccttggttt
     4621 caatatatgg ataaaggact tattagacct atatctttaa agcctaacca atcttataaa
     4681 ctaaaagtga ttgttgatga caatataatg acactttata ttgatggaat cgctcttaac
     4741 gctcgtgtac atggttgttt tggtcaagca attactatta cagcaacaaa tggatcaatg
     4801 actgcaataa ataccaagtt ttcaaatgaa ataaagaaat aataaacgtc aatcatgtgg
     4861 caggtctgaa aatcaaacat gacctgtcac atttaaaagg gaggataaat gaatggacta
     4921 caaaaaaatt gccgaagatg tattggaaaa cgttggagga aaagagaata tctcaagcgc
     4981 tacacactgc attactcgtt tacgtttaat tcttaaagac aaaagcaaag cgaatatgga
     5041 aatgcttgag gaaatagaag gtgcaaaagg tgttcttttc aatagtggac agttacaagt
     5101 aattttcgga acaggtataa ttgaaaaggt ttacaaagag ttcgttgaat tgacaggagc
     5161 taaggaagta tccgtttctg aaatgaaaga cgaaggagtc aataattcag gaaatagact
     5221 tcaacgagct tttaaagttt tctcggatat ctttattccg atcattccag cttttattgg
     5281 ggcagcaatg gttttaggaa ttcgttcgtt gattaccact cctggaatgt ttggaatgga
     5341 tggctcattc gctgatcaca atgtattcct aaatgattta tccaaatttc tgggtattat
     5401 tgcaaccaca tttgattatt taccagtttt agttatgtat tctgcaacaa aacgttttgg
     5461 cggaaaccct attttaggat tacttgtagg atttgttatg attcatccag gactagccaa
     5521 tcggaatgat ttcgtcatgg gaactataaa gcctgattat tggcatttat ttggattaag
     5581 cattccagca gttgcgtttc aagggggtgt ttttccagca attttgactt cttggttttt
     5641 agcaaaagtt gagaaaatta caaataaata ttctcctcaa gtacttgctt acattttagt
     5701 cccaactgtg acaattgttc ttgccaactt tgcactattt ttagtgtttg gtccattggg
     5761 gaattttatc ggtaatgttt taggtggaat cattgatttc ctatatatga agatgggtgc
     5821 ctttggtgct tttgtttttg caggcgcgtt acaaccatta gttgtaacag gaacacaaca
     5881 tgctattcaa ggtattgagg caaacttagt cgcaacaact ggattcaatt atatccaacc
     5941 tatttggtca gtttcaatta ttgcccaagg tggcggttgt attggtatgt atttactctt
     6001 taagaaaaaa tctaaagata gagatattgc gatttcaagc tttattccaa cactggtagg
     6061 tattactgaa ccggctatct ttgctgttaa tttgaaatat tcaatcgttc cttttgtttg
     6121 ctcgtttatt ggtgctggtt ttggtggagc atttatgaaa atttttgatg taaaagccat
     6181 tggacaagga ttgactgtat tgccaggtct gactattgct aatccagttc ttccttatat
     6241 atttggtaat ctcatagcat tcattttacc aatcattttt attctcgctt atgataaata
     6301 taaagtgttt atccctgaag ctaaacaccg taaatttgca gaaaaaactg actcaaaaaa
     6361 attgccagtt caagtaaagt gagatgagag catgttaaat ttttttagaa aaaatgaaat
     6421 aagcgttgta gcacctgcaa ccggtgtttt tgaaaaactg gagaaattaa gtgatccagt
     6481 cttttcaaaa ggaatgatgg gacaaggatt tgcaattgat gcaaaaaacg aaacgattgt
     6541 atctccaatc gatggttttg tttcaagtat ttttcctaca aaacatgcct taggaataaa
     6601 aacaaaatca ggaattgaga tacttgttca tgtaggaata gatacagttg agctaaatgg
     6661 tgagggattt gatattaaag ttcaagaagg acaaaaagtt aaggctgggg atattcttat
     6721 gaccattaat tttgtagttt ttgaaaagaa tcacaagact aaagatgtca ttgttgtttt
     6781 tccagactac caagacgaaa ttttcattcc gaaacttgaa gaagtaaaac aaggacaaga
     6841 attgtttgtt cttggctaat gataagtaat taataataga atcgaggaaa atgtatggtt
     6901 tttggggcta ttgaagctgg tggaacaaaa tttgtttgtg ccattggaga taaagatttg
     6961 aacatatttg aaaaagtcag ctttcccacg actacaccca aagaaacaat gaatttagtt
     7021 ttagattttt ttaatcatca taaagatgat ttagaaggta tcggagtggg atcgttcggt
     7081 cctattgata ttcattgtga atctaaaacg tatggcttca ttacatcaac gccaaaactt
     7141 gcttggcagg attttgattt tattggaagt ttaaaaaagc aacttaatat tccaactgct
     7201 tggacgactg atgtaaatgc ctcttgctat ggtgaatatg tttctggaaa tggcagaggc
     7261 ctttcaagtg ttgtttacta taccgtagga acgggcatag gaggtggcgc tatccaaaac
     7321 ggaaacttca ttgaaggttt tagtcatcca gaaatgggac atatgcttgt aaaacgacac
     7381 aataaagaca acttttctgg gacatgtcca ttccacggag actgtttaga gggcttagct
     7441 gctggtccgg caatcgaaag aagatcaggg aaaaagggac aagaagtgac tgaaaatgac
     7501 gttacttggg aaatagaagc ttattacatt gctcagtgtg catataatac aacattgatg
     7561 ttatcacctg atgtcattat atttggtggc ggagtaatga aacaaaaaca cttaaaaaag
     7621 aaagtacaag ataagtttat tgagttgatc aacggatatg tcgctattcc cgatgttgac
     7681 aattatatta tgacaccaaa attgttagat aattctggta ttgtaggttg tttagcttta
     7741 gcaagagacg ttaaagaaaa atcttaattt ggaaaaaaga tcgtctcgac tatttgtttg
     7801 gttgatgcga tctttttttt caattagtaa ttgaagggac gcctaaaagt gaaaaaaaaa
     7861 atgaaagatg aagtattaga gtatatcaaa aataatttaa agtattacga tttttctgct
     7921 caagatattg caatgaaatt ttgtattaaa agaaatgtcg cttcccacta tttgaatcag
     7981 ttattttcag atggaaaatt actaaagaat gattctgtta gaccagtaat gttcaagtat
     8041 aatcaacaaa agccaaaaga ctgcttttct aagtttattg gagcagacat atctttgaaa
     8101 tccactatag ataaatgcaa agctactgta atgtatcccc ctaatggcct cccattaata
     8161 ataaaaggaa acagtggcgt tggaaaaagt tttttagcaa gtttgatcta tcagtatgct
     8221 cttgatagaa aagtaattca taatgacgca aaatttgttg ttgtgaattg tgcagattat
     8281 gcaaataatc cagagctatt gtcagcagtt ttatttggat ataaaaaagg agcctttact
     8341 ggggctgaaa aagatactgc agggatgcta tcttctgcta atggaggata ccttttttta
     8401 gatgaggttc acaatctaag tgcagaaaac caagagaaat tgtttcttct tatggattct
     8461 caaaagtatc gtaaacttgg tgaaagtgtg caatgggagt atgcaaatgt tcgccttatc
     8521 ttagccacaa cagaagataa aaatacctct ttgttagcaa cttttagaag acgcatccca
     8581 gctgaaatca ctctgccaga ttacaataat agaagtacat ctgaaaaaat tcaattatta
     8641 tttgaatttc ttaaagatga agcaattaca attgattcaa aaatattttg ttcgattgaa
     8701 ctttttactg atcttttatc gaaaacattt gaaggaaatg ttggagaatt gaggaatgaa
     8761 atcaagcttc tttgtgcaga aggttattta ggaaataaga gaaagtcttc aatttattta
     8821 ggggacaaac tagacagcgg tttttggata gatccagaaa ttagtataga tttaaaaaaa
     8881 atgtttctta aatcactttc tgaaattgat ttgattgaac tttttcaaaa tcacatttca
     8941 attgaagaaa gcatgagtca attaagagat agaatactta aagagtgtgc aggttcttct
     9001 gagtataatt atttagaaag tgacgaattt atagcattaa gaaactatgt tgttaataaa
     9061 atatcaccaa ttattgattc gacaggtcta tgtttattag atgaattctt ggcggatatc
     9121 agtctattta taatgtttat tgatgtaatt gaagaaacat caagaaattt tttgctgtct
     9181 aagttcagaa aatttcgtat gaaaaatgat aaacaaaaat tattggcaaa tgagatttgg
     9241 agtagtttag aagtcgaaga aagtaaacaa gaacttttgt tgaaatggat actttttctt
     9301 gtaaagaagt tctatgtgaa aataccagaa acccattgtc tgatagttat gcacggtaaa
     9361 ataacagctt ctgcgatcgc aagggaaaca aataagttgc tgaatacata tgtttatgag
     9421 gctttcgata tgccaattga aggtgagact agtgacttaa ttaacctaat caacaatttt
     9481 tgtaaaagta tagatacgac gaatggactc attctgctag ttgatatggg atcattggaa
     9541 caaatgtatg aaaaaattga atccaatgta ataggtgatt tggtaatttt aaacaatgtt
     9601 tctacagctt tagcgattga atgtgggatt caagtttgcc aaaaaaagcc aattagtcat
     9661 ttttaccaga tggattttga ttcgtttcaa gttaaagttc agtattataa aggattatca
     9721 caaaagaaaa atgtaatagt atcttgtctc tctggtgagg ggatttctga aaaagttaag
     9781 gatattttaa aacggtatct cgataatcaa gtggagattt tgatttttga ttttaacgca
     9841 ttaaagaaaa tagcaaagga aaaagatact atgattttta agaatacaat ttgtgttctt
     9901 tcaaccactg aattttacat tcaaggaatc gattgtttaa atttagaaaa tctaattaat
     9961 gggaatcaaa ccttagaaaa attaaataag tatatggact cggatagctg tgagttctgc
    10021 ttaaatgaat tagttaaact ctttactatt gaaggcgcta gtactaagct tcgcttttta
    10081 gattccaaaa aagtattcaa tgagatagaa aaagtactat atttgtatga aaaatattac
    10141 gatgtcaaaa tcccaagttt tctgagaatt aatctatttc tacatctttc tggaatgatt
    10201 gaacgaatta tgattggtga tggaataaca aatgaacatt tgaaagaggg agcgcaacta
    10261 tttgatactt ttttaaatgt atcaaaagat tttttttcag aaatcaaaga tatttactgt
    10321 attgaaatac ccaaaggaga gtatgagtta atctatacaa tttttgagca gactattttc
    10381 taaatagcat actagcgtct aaaaaaatga aagggtgtcc aaagtatatt tagacgctca
    10441 tttaattaat atttactgta ttttcccgct ttattggata atgttagttg gcacagtaat
    10501 tgcttatata aaagtataag aagaaaggag agaacaaaat ggcgttttgg caaacatttt
    10561 tagttgtgtt gtatggattt ttcattaact gggataagga agggcccaaa atcggaacct
    10621 cccaacctgt cgttgcaggt ttcttgaccg gacttattat gggagatatt caaactggac
    10681 tttatatcgg tgggactttg caattaatga cactaggtat tactagtttt ggtggtgcat
    10741 cagtaccgga ttatcaaaca gcagcattga tcggtactta tttagcaatc tcaactaacc
    10801 aggatgcttc tataggaata actttagcaa taccggtagc aatgttaatt gtacaactag
    10861 atgttctaaa gtggtcaaca aacatttttt ttcaacaaaa ggcagaaaaa ttcgcacaaa
    10921 aagaagatta tcaaaaatta gagtggatgc aatatttggc atcaattaat acaagctttg
    10981 tatctggaat tcctgttttg ttaactgtga tattaggccc aacgttagtg ggaagtgcaa
    11041 tcaattatat tcctgaatgg gttaccggtg gtttaaaggt agcaggggga ctattacctg
    11101 ctgttgggat aggaatgcta cttaaatatt tacctacaaa agattacttt gcctatttgt
    11161 tagttggttt cgttttggca gtttatttcc aaataccaat tttagggatt tcgttacttg
    11221 gcgctgcaat cgcactaatc gtatataaaa atagatcaaa taatactcaa gtagcaccag
    11281 ctgcaacagg aggttttgac gaagatgaat aagaaactga caaaaatcga caaacaagta
    11341 attttccggt ggattctcaa tggtgcaact tcattaaatt atgaaaaaat ggaagggttg
    11401 ggttatgcgt attctatgct tccttttatc aaggacacat ataaagatga tcctgaagga
    11461 atgaaacaat ccgttttagc tcacctacaa ttttttaaca ctacgccgta tacagcgcct
    11521 tacattattg gtatgaatgt tggaattgaa aaagaagaaa aaaataagtc tttggaagca
    11581 gtaagtgctc tgaaaacagg tctaatgggt cctttagcgg gaattggaga tagtgtattt
    11641 gtagttattc catggactat ttttggagca attgcagcta atatggcatt ggaaggtagt
    11701 tttgttggaa ttattttgtg gatactggca tcaattttat taaggattac tgcttatcct
    11761 ttataccttg ctgggaaaga atcgggtgcg agcctactaa ctcaaattga aacaaaatta
    11821 aagtctatta ctgatgcagt atcaatttta gggttaatgg tggtcggtgc actcattgcc
    11881 acagttgtaa aagtgaatgt tggctttgaa tttaaacaag gcgacttaac aatgaccgga
    11941 aatgaaatct ttgatcaagt tatgcctggt ttattacctg catgtgtagt agcaattgtg
    12001 tattatttgt taggacgaaa ggttaaacca gtttatgtaa ttctattaat cttagtagtt
    12061 tctattgcgt taagagcgtt aaatattttg aagtaggtgt tgaatatgga tgaaaaaatg
    12121 aaaggtatta tacatgttcg tattgatgat cgaatgattc atggacaagt agcaacacaa
    12181 tggacaaatc aattgagtgc taacagaatt atggttatta ataatgaagt agccaatgat
    12241 gacgtaaaaa aagctgtagt tcgcctcgct gcaccaccta atgttagaac ttcaataatt
    12301 acaagggaag tagcagttaa aaatattctt tctggtaaat atgaaggaca aaaagttctt
    12361 attgttgcag tttctccaat cgatgttaaa tttttgattg ataacggttt accaataaca
    12421 agtgtaaacg taggaaattt atcaagaagg aatggaacag aacgcatccg tccgacgata
    12481 aatattactg aagaagagag agaggctttt aaagaactaa ttagtgatgg agttgaagtg
    12541 acagtgatac aaactcctag agattcaaaa gaatttttaa aggattttat ttattaagaa
    12601 cagaggatga gtggatggag tttataatta catctcatgg aaatattgcc attggatttg
    12661 tagatacatt aaaaatgttt tttggcgata atttaaattg tcatgtggta acacttggag
    12721 atgcaggcat tgaagaattc cgtgaaaaca ttgaaaaaat agtttctcaa gtaaaaaatc
    12781 aagaagttat ggtatttgct gacttgattg gtggaacacc tttcaacgaa tttgctaaaa
    12841 gaagtgaagt atttcaaaat gggtttcaac ttcttggtgg catgaattta ggaattttga
    12901 ttgaggctgt caatttgaga ttacaaggaa aaaaaagcga tgatatcatc gaaaatctaa
    12961 gaaatatgaa tacaattgcg tgtcttgcag atatgcaaag acatactaac gaagaggatg
    13021 agtgataaat gcaaaaaatt ttttacaagc ctaaagattt ttggtttggg gattgcatgc
    13081 ctttttataa agatggaact ttttatctat ttcatcaacg agatacgaga aatcctaaac
    13141 ctttaactga tccttttggg tggtcactag ttacaaccac tgattttgtg aaatttgaag
    13201 aatacgggga agtaattcat cgtggtggca acgatgacat tgatcaatac atttacgctg
    13261 gaagtattgt ccaaggaatc aatgagtatt tagctttgta tactggacat aatcgcaaag
    13321 ctaagttgga tggaaaaact tcagaagtgt taatgattgc aagttctaaa gatttaattc
    13381 attggaaaaa ggatggcgaa gcagcaaaac ttgttcctca agaaggatat gataagaatg
    13441 attggcgcga tccttttgca atttttgatc aagatcatgg aaaatacgtt ttgatactag
    13501 gagctagaaa accagcaagt aagaaaaagc cgacggggag attggtctat tttgaatccg
    13561 aagatttaaa agattggaat ttcaaaggag actactgggc taataatgaa tttaacatga
    13621 ttgaaatgcc tgatatattt gaaattgatg gaacgtggta tttacttttt tcagagtatt
    13681 gtgaagataa aaagactaaa tatcgagtcg gagcaggatt attttcagat tggaaatcac
    13741 cagtagacga agctttcgac ggaaaagcct attatgcagc aagaacagtc ggaactaatg
    13801 aaactggccg ttttctaact ggctgggtgg caacaaaaga aggggagaac gatcaaaata
    13861 actgggattg gggcggtgca cttgttccac atcaaattat tcaaaagaca gacaaaactc
    13921 ttggtgttaa actgcctgaa aaaataattg agaattttaa agaaatcact ccattttcaa
    13981 gttttaagtt agagaaagaa tttggaaaaa aagaaagagt aattgttcct aaaatcgaag
    14041 attattttct atttgaaaca actttgacta ttacatcgtt aacaaaggag tttgctttaa
    14101 aattatttgt agatagtgat actcaagaag gatacgaatt tcgtatttca ttgattaata
    14161 atcagcttac tttcggaaaa actccgaact atccttggcc tcaaatgttt gataaggggc
    14221 tgcaacgacc actatttttg gaaataggca aagaatatga actaaagtta attgttgatg
    14281 atacgatagc tgttttatat attgataatg ttgctttaag tactagaatg tatgataaag
    14341 tcggaacagc attaagtatg actgttacgg agggagcaat caaggtagat aaactagact
    14401 attcaataaa ttatgaatgt ggattttaaa acaattgaag ggatgatgta agtgaaatta
    14461 aatggtttac aacatattgg aattccaaca aaagattttg gagcttcaaa aatcttttat
    14521 gaatccttag ggtttagtct gattaatgaa gaaatgaatg tgggaagtaa agtcggcttt
    14581 ttcgagttga atggaacgat aatagaaata tgggaagata aaactactga gtgtagagga
    14641 gccattgatc atctagcatt agatacggat gacatagatg aggtattcaa ttcaattcaa
    14701 gatttaggat atgaattatt agataaaaat attatggaat taccgttctg ggaaaatgga
    14761 atccgttact ttaatttcta cggaccaaat catgagatta tagagataag ccaaatgaag
    14821 aaataaatag ataacgaagt gctctaagtt ggtatgaacg aaaagtactt cattttttgg
    14881 tatcagcatt tcaatagttt aatgagaatt tactatttca aattaattca aagtgacagt
    14941 attttttact tatttggttt caaattttgt aatccttcct atttattgga atacactcca
    15001 cattttgtat acaagtcata tcatgtttta gcaaagctct taccaagcaa agttataatg
    15061 atgttttcca aagtttgatc tttcgatgga ggctaacaca tattttttgc aggacagcca
    15121 aaattagatg tatagaatag agtctgtgag gcgtatagac agtttattgt ctgtatgcct
    15181 ttttttattt tgaaaaattt ttagtatttt tcgaaaaatg ctcactccta gagtaagcgc
    15241 cccatagaac agtaccttac taacaaatgc acctcaagat atacttgagc tatcaagaag
    15301 tctggaggtt ttct
//
LOCUS       DADLIO010000061        15255 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.064, whole genome shotgun sequence.
ACCESSION   DADLIO010000061 DADLIO010000000
VERSION     DADLIO010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15255
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.064"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            248..1021
                     /locus_tag="JOX41_002136"
     CDS             248..1021
                     /locus_tag="JOX41_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HAY6449856.1"
                     /translation="MHGDEWQLVAKKNDGWLFFFTSIFIGAMLLIGGKQGLFALGSLI
                     INIVLLLLLLLIFTKTEGISLLNKSILFVVIGMIISILALDGWNRSSIIKISAAVTSV
                     FLAFFICLLTMNHWKDQGLRYEELNYLTRPYRSVFLSSVLIGTAGGTLDTVITVIATL
                     EELTKRQPEITAKQLWLSGRQVGRDVIGSMTNILLFVYISGSVPSLLLYLGNQWSFKE
                     TIEQHLSLEFLRVIAGSLGIVLSIPISVLFFLTVRRLKR"
     gene            1018..1785
                     /locus_tag="JOX41_002137"
     CDS             1018..1785
                     /locus_tag="JOX41_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HAY6449857.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALIVLPLTCVTTAYLFTKKKEQLKME"
     gene            1885..3453
                     /gene="liaX"
                     /locus_tag="JOX41_002138"
     CDS             1885..3453
                     /gene="liaX"
                     /locus_tag="JOX41_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HAY6449858.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDKASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQALEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDDEIAQVQL
                     STTTGSIYLKDTDK"
     gene            3753..4070
                     /locus_tag="JOX41_002139"
     CDS             3753..4070
                     /locus_tag="JOX41_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HAY6449859.1"
                     /translation="MKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVAF
                     GSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDEW
                     SDF"
     gene            4070..4420
                     /locus_tag="JOX41_002140"
     CDS             4070..4420
                     /locus_tag="JOX41_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HAY6449860.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            4587..5525
                     /locus_tag="JOX41_002141"
     CDS             4587..5525
                     /locus_tag="JOX41_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HAY6449861.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            5540..6370
                     /locus_tag="JOX41_002142"
     CDS             5540..6370
                     /locus_tag="JOX41_002142"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HAY6449862.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            6414..7439
                     /locus_tag="JOX41_002143"
     CDS             6414..7439
                     /locus_tag="JOX41_002143"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HAY6449863.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGIGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            7454..8392
                     /gene="galU"
                     /locus_tag="JOX41_002144"
     CDS             7454..8392
                     /gene="galU"
                     /locus_tag="JOX41_002144"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAY6449864.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYIMSLGKTLEAEGSKINHNPKGITEIKEEKKK"
     gene            8517..8957
                     /locus_tag="JOX41_002145"
     CDS             8517..8957
                     /locus_tag="JOX41_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HAY6449865.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTQDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIVTKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            8960..9562
                     /locus_tag="JOX41_002146"
     CDS             8960..9562
                     /locus_tag="JOX41_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAY6449866.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSSELTGIAKEKAQGLSQQAGDLAGNVKQKVSESAEEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDLKKPADELGSIAKDTSEDIMIDVKDAADKAGETVNEG
                     MSEAKPVADDTKEMLKMAKEDAKEAKKEMKDTMTDSTTNH"
     gene            complement(9625..10728)
                     /locus_tag="JOX41_002147"
     CDS             complement(9625..10728)
                     /locus_tag="JOX41_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAY6449867.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVDRFDAISDILTGTDSYTDLTSIIQRLQLIKTVEEKDKLIEAGKWADVAF
                     EIGFKTVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGSTKVSP
                     NELVLFDLGVIWNGYCSDATRTVAYQKPTEFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLE"
     gene            10938..11939
                     /gene="ccpA"
                     /locus_tag="JOX41_002148"
     CDS             10938..11939
                     /gene="ccpA"
                     /locus_tag="JOX41_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HAY6449868.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            12294..12689
                     /locus_tag="JOX41_002149"
     CDS             12294..12689
                     /locus_tag="JOX41_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449869.1"
                     /translation="MPKKRRKTIVIILTILTIGIGGKFYMDKREMQRQKDLLAVEKQS
                     VKVLKNTFADIKEVKIEKSARNEMTGSYRIVILMTNKQDQSIYFSYSFWKERNEIGSY
                     GIVDEKKQKEGNTLNKVKVTYSNGNEESI"
     gene            12689..12940
                     /locus_tag="JOX41_002150"
     CDS             12689..12940
                     /locus_tag="JOX41_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449870.1"
                     /translation="MITDKQYSELSDAVYWLDPKHRDYVPEMQENLSFKINGTMYKIL
                     KIKNSFDGMQAMAVAPIVHSKLEKNFKNKKIPANFRVLK"
     gene            12983..13378
                     /locus_tag="JOX41_002151"
     CDS             12983..13378
                     /locus_tag="JOX41_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449871.1"
                     /translation="MSRKIRKLSLAILLIVILGIGGKVYMDKREAQRQKDLLAVEKQS
                     VKVLKNTFADIREVKVEEFKKNPVTGSYGALVTMTNNEGKSVYFDYSFWKERNELGGF
                     GIENRAVQKTGVTIKRVKVIFSNGQEELV"
     gene            13375..14631
                     /locus_tag="JOX41_002152"
     CDS             13375..14631
                     /locus_tag="JOX41_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HAY6449872.1"
                     /translation="MTINDKHYNDISEKVYWLDPKYPRYNEGYKKNSVKEFAGMEFQI
                     LQIKDSLDGMQAMSVAPIKNGKVDLSQVVIAFAGTNLSDWKDLETDARSIMNLYGNRP
                     GASFSEKATTNKILSVSGLKTAGQINSAIAFANEVKKEYGEAAISTTGHSLGGFLALY
                     VAAEKQWKNVGFNGPDPYDLLSPEAKKWVEENPGMLTNYRNHADFIGNFGGNGTGAEV
                     RISMETAFLNLLASHSLTSWKFDENGKLIIPENENNVKARKQQKENQATQLFSYQLQE
                     LNNIRKKLRLSGGRLTVNEQIYLDDTQARLVVEKLSAKMKSAMEEVIRINQRGIFELE
                     KKWQEGLRQARVVAPSLTEQEIIEALASVGATKENLVDSAKEVYLLRINKARRMGEAF
                     DTLAKEIQDKINEIVARDRELAQQFN"
     gene            14643..14966
                     /locus_tag="JOX41_002153"
     CDS             14643..14966
                     /locus_tag="JOX41_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449873.1"
                     /translation="MKLEELERDYRSERRQLEAQEDELIHFKNQGLRLMEQEEQRLHH
                     VLKNLALDNEPLFQARRSYSNYQEHYQQALQVERRKLYQQQDELERSYRQKIRQITME
                     KSSYE"
     gene            14959..15225
                     /locus_tag="JOX41_002154"
     CDS             14959..15225
                     /locus_tag="JOX41_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449874.1"
                     /translation="MNEFLMQLLKELEKNLHRSNVRSVGMGISQQIWAEKRLTDQNYQ
                     MTAEEAAQEFSNRHVHLKGSVKGQFAEKLTELFQRQEKKLKQFR"
BASE COUNT         5242 a         2580 c         3225 g         4208 t
ORIGIN      
        1 aattagcatc atcactatat tttttatttg tgtgcttact tcatgggtta ttcagcatca
       61 agccgcttta tatgaagtac ctgtcatcga gatagaaaaa gtacgaataa aagaggatca
      121 tcaattgatt acaggaaaac tgatgaactc ggatcaaaaa ggagaatcga tttatttatc
      181 ggttccttat caaaaaaatc aaatagaaac agcaaatata aaagcgagac aaatgtatct
      241 agtccaaatg catggagatg aatggcagct agtagcaaaa aaaaatgatg gctggctttt
      301 cttcttcaca agtatcttca ttggcgccat gttgcttatt ggcggaaaac agggtctatt
      361 tgctttagga agtctcatca tcaatatcgt tttactttta cttttgttgc tcatctttac
      421 taaaacagaa gggatttctc tattaaataa atctatcctg ttcgtcgtta tagggatgat
      481 tattagcata ttggctttag atggatggaa tagaagcagt ataatcaaaa tttcagctgc
      541 agttacgagt gtttttttag cattttttat ttgtcttttg acaatgaatc attggaaaga
      601 ccaaggactg cgctatgagg aactgaatta tctgacacga ccgtatcgtt ctgtttttct
      661 ttctagcgta ctgattggaa cagctggagg aacactcgat accgttatca cagtcattgc
      721 gacattagaa gaattgacta agcgacaacc agaaataaca gcgaaacagt tatggctttc
      781 aggaaggcaa gtgggtcgag atgtgattgg ctcgatgacc aatatccttt tgttcgtcta
      841 tatcagtggg tcagttccat cgcttctttt atatttagga aatcaatggt ctttcaaaga
      901 aacgatagaa cagcatttat cattggaatt tttacgcgtc attgctggca gcttaggaat
      961 agtattatcg atccccatct cggtcctctt ttttctgact gtaaggaggc tgaaacgatg
     1021 aatgtactta ttatacttgt tgggatttta gcaatcagcg tgctacttat tggcggtacg
     1081 caaggtatgt atattctttt aggcttattc atcaatttag ggatcttttt cctgttgtta
     1141 ttcggttatc atcagaagtg gccgatactg gcattgtcgg tcataggatt tttattgatt
     1201 gctgtggtta tcttattttt tatcaacggt tataatctaa aaatgcgtgc agcttttgtg
     1261 agtatactga tctttttatt ttgtttccta ctattgcttc ctatcactga ttttttagcg
     1321 atccaaggtt ttacatcggt agaactagaa gaattatctg gcttagataa gactttagcg
     1381 attgatttta gattacttac gagatcgttg cttctgatta gtcttagtgg tgctgtttta
     1441 gatgcgagtg tagcaatttc tagtgggaca ttcgaagtat atcaggcaaa tccgcaatta
     1501 tctttttacc aattgcgcca ttctagtttc gctattgcta aaaaaatatt ggcgtcaaca
     1561 gtaatgacac ttctttttgc attcatggga agttctttag cgttgatcct ctggtttatt
     1621 gatttagaca ttccttttca gcaagtgatc aatgaaaaat catttgttct agaatatacg
     1681 atggctattc ttaccacatt gtccgcacta attgttcttc ctttaacctg cgtgactaca
     1741 gcatatctct ttacaaaaaa gaaagaacaa ctcaagatgg agtaaaagtt acaacttaag
     1801 tcctatgaca tttttactga atcagtgcat aatatggatg taaggaaaag cttgcaaaca
     1861 attttgctta aggaggcaat ttccatgaaa gaaagagaac gtattttaga tttagtgaaa
     1921 aaaggaatcc tttcgactga agaaggctta gatttattag aaagcatggc aactgaaaaa
     1981 gacgaaaagc aaatcaaaaa agaagcagac aaggtaactg ctagtcataa agaaaaagat
     2041 aaggcaagtc aattgatcga taaacttgaa aacggcgaag aagaaatttc tgagccagtt
     2101 gatccaaagg aaagagaaag acaagatcaa gaaaacttag aaaagatctt agatgaacta
     2161 gcaactgaag cgaataaaac ttcggcgcgt ctagatgaag taaatgctca attcgctgac
     2221 aataaggcag cacgcaatga gaaacaggaa gcattgatgc agctgaatac aaaagaagaa
     2281 ttaggcgagt tgacagaaga agaattagca cagcgtcagg cgttagaggc agaaatcaaa
     2341 gagttagaag ctagtggcga tacactgtta gaagaacaat tgaaattaga agcagaatta
     2401 aaagatatcc gtaagaatca atggtctgag aaaaaagaaa cgtttactga taagtttgaa
     2461 ttgccagatg attggaaaga tcaagcaaca gatacactga atcaagtagg cgaaaaaatg
     2521 tcagaagctg gatcacagtt aggcaaattc ttgaagaaaa cattccaaac tgtttcagaa
     2581 acagtgaatg acaacatgga atggaaagat gtcagcttac gtgtccctgg gattgcgaca
     2641 acgaaatttg agcatgaatt ttactatgaa gctcctgcag caagtatcct tgatatcaag
     2701 gcagcaaacg gaaacgtgac gttaaaaacg tgggacagca acgatgtgaa agttgaagct
     2761 aagatcaaac tttacggaaa aatgggtgct gaaccatttg aagcattctc tgaacggagc
     2821 cagattgagg ttaatgaaga tcatatctcc ttccaaattc caaataaacg tgtgcgtgca
     2881 gaccttgttt tctacttacc taaacgagta tacgaccacg cagctattaa acttctaaat
     2941 ggcaacatca tgattgaaac attggaagct aaagatattt atacaaaatc tacgaatggt
     3001 aacatcatcg tggaccaatt aactgcaacg atgctggaag tagaaggtgt aaacggcaat
     3061 atcgatattc gaaacgggaa catcttagat tctattatcg aaacagtaaa tggtacagtg
     3121 acatttggtg cgacagcaga aaatctttct gtgtctttag taaatggtga tgtacgtctt
     3181 acgattaaag aagataattt gaaaaaagta gaagcaagtt cagtgaacgg aaatgtcaaa
     3241 gtcgctttac cagatggcat cggtttggaa ggacatgcta aaacaagtct tggaagtatc
     3301 aatagccgtc tgtccaatta cgaagtagtt cgtgagaaaa aagaacggac aaaccaaatg
     3361 ttgcaattcc gtcgtgtttc agatgatgag atcgcgcaag tgcaactttc aacgacaaca
     3421 ggaagtatct atttaaaaga tacagataaa taaagaggtt gtgaaagaga tgttcagcct
     3481 tgagcaataa gaagcgattt tgtaaaatag cttcccctat tttacaaaat tgtgccttat
     3541 tgccgatagt ctatctcttg aacaccgttt accaagagat tatgaacctg ccaattatcg
     3601 ccgagtcaca aggaataatt tcagaaaaag ctcgtcacgt tttatgaata tggtaatttg
     3661 tgaccgagaa ttttgcagaa agacaccgat taagaagaag gttgtcacaa cgattttctt
     3721 catttaaaat agtagaacag aggtgagaca tgatgaaaaa aaagttgaca aaatctaata
     3781 aaaatgttgt tttgacaggg actttagcag gaataggaga atacatcggg attgatccga
     3841 ctgttatccg tgtgctttat gtattcctga gcttagttgc ttttggaagt ccaattattt
     3901 tatacatttt attagctttg attatcccat ctgcgcgttc tgcacgaaca aactatggac
     3961 ataacaatgc atattatgaa aaaaacaatt atcgtgaaca aactcgtgaa caaacaaaaa
     4021 aacgcaaaga agcggaaaaa atcgatgatg acgaatggag tgacttttaa tgtcgtactt
     4081 tcaacgtatt ttagttaata cgttaacatt catatcattg gctgttcttt ttcctgcgat
     4141 ggtccatgtg agcagtattt ggacggccgt tcttgccagc ttcgtattgt ctgtgttgaa
     4201 tatgtttgtc aaaccgattt tgacgatact gtccctgccc tttacattag tcacattggg
     4261 attgtttacg tttgttatca atgcagcgat tcttaaaatg acctcctttt ttgtgggagc
     4321 agaacatttt agtttttctt cattcggtgc agcgttgtta gtagctatct tgatgtcgct
     4381 tgtcaatgta attgtcagcg aacataacag tagaaaataa aagaaagctg tgccgaacta
     4441 tcggcgcagt ttttttattt agaatcagga atgcgttttc tattacattg gtaattaaat
     4501 aaaaacgttt tttttaattg gtagtacttt tggctagaca atgataaaat gatagagaac
     4561 actctaatag aaatgaggta gcatgaatgt cagaagttgt aaaagttagc caattagtga
     4621 aaaaattatc tttggaaatc gtgacaggcg acgagaaaag cttagaccgt gtcatcgtaa
     4681 ctggggacat ctcacgccca ggactagagt tgactggtta ttttaattat tattcccata
     4741 atcgtttaca gctatttggc agtaaagaaa tcagttttgc ggaacggatg atcccagaag
     4801 agcgtttgat catcatgaga agattatgta gtgaagatat gcccgcattt attatttcaa
     4861 gaggattacc agctccagaa gaaatgatcc aggcagcaaa tgaaaatggg atagctgtac
     4921 tgcgttctcc catctcaact tctcgtttat taggagaatt atccagttat ttagatggtc
     4981 gccttgcccc tcgaacaagt gtccacggtg ttttagtgga tgtttacgga ttaggtgtac
     5041 tgattcaagg tgacagtggg ataggaaaaa gtgaaacagc gttggagttg atcaaacgcg
     5101 gccatcgatt gatcgcagac gatcgagtag atgtttatca gcaagatgaa ttaacggtga
     5161 tcggagaacc gcctaaaatc ctggaacatc tgattgaaat ccgaggaatc gggatcattg
     5221 atgtaatgaa tctttttggt gcgagtgcgg tacgtggctc tatgcaagtc cagttggctg
     5281 tttatctgga agcatgggca aaagataaga aatacgaccg tctgggctct gaagacacga
     5341 ccgttgaaat cgcggaagtg ggcattccac aaataaaaat ccctgtcaaa acaggacgaa
     5401 acgttgcaat catcattgaa gtagccgcga tgaatttccg tgcacgtaca atgggctttg
     5461 acgcaacgaa aacatttgaa gaaagattaa gtcgcttgat tgaagaaaac tcaggcaacg
     5521 actagcaagg agtgacaata tgttagcaca aatcaatcga gttgcttttg agcttgtagg
     5581 gattcctatc tactggtatg cattgatcat cgtatcaggt atcattatcg ctatgtggct
     5641 tagcagcaga gaggctgttc gggtaggatt aaaagcagat gatgtgacag attttatgtt
     5701 gtggggattg cctatctcca ttattggcgc tcgcttatat tatgttttat ttgatcttcc
     5761 ccagtatata gctgatccaa tccaaatatt caatatccgt tcaggaggct tagctattta
     5821 tggcggactg attgcaggcg cgatcacgct gtattttttt actaaatatc attttatttc
     5881 tttgtggact tttttagata tcgctgcacc aagtgtatta ttagcacagg caatcggtcg
     5941 ttggggaaat ttcatgaacc acgaagcata tggaccagac acgacgcgaa gcttcttaga
     6001 aagtctgcat ttaccgcaat tcatcattga taatatgtat atcgaaggga tctatcgtca
     6061 accaacattt ctttatgaat cactttggag tttgattgga tttattttgc ttttgttttt
     6121 acgaaagaaa ccacaccttt tgaaaaaagg cgaagtcctt ttatgttatc taatgtggta
     6181 tagtttcggg cgtttcttta ttgaaggatt acgtacagac agtctttact ttttaggtgt
     6241 gatccgtatt tctcaattat tatctgctgt gttatttgtc ggtacattga ttctatttat
     6301 ttggcgcaga aaaaaaggaa atttaccgga ttatgaccgc tcattaggaa aaaatcaaca
     6361 aattatctga tttttagagc gttaaaaatg aaaaaaattt caggagtggt aaaatgaatt
     6421 atagagtagc ggttttagga ccaggctctt ggggtactgc tttggcacaa gtcctcgccg
     6481 aaaacggaca tgacgttcgg atttggggac atcgtgcttc acaagtagaa gaaatcaaca
     6541 cccaacacac gaatcaacgt tatttaccag atcattatct acccgattcc atccaagcat
     6601 tcaccaatat ggaagatgca gtaaaagacg cagatgcggt gctattcgtc attccaacga
     6661 aagcaatacg ttctgttgca aaagaactag tgcctaaatt gaatacaaag ccagtgatca
     6721 tccatgcaag taaaggatta gaacagggaa cacataaaag gatctctgac atcttgttag
     6781 aggaaatccc agcagaaaaa agaaaagctg ttgttgttct ttctggacca agccatgcag
     6841 aagaagtagc aaaacatgac atcactacga tcacagctgc aagtacagat gcaaaagcag
     6901 caaaatatgt acaagagctg ttcatgaata attattttcg gatctatacc aatcctgatg
     6961 tgatcggtgt agagatgggg gcagctttga aaaatattat tgctattggt gctggcgcta
     7021 ttcacggctt agggtttggc gataatgcaa aggcagcaat catgacgcgc ggattagctg
     7081 agatcagccg tttaggtgta gcaatgggtg ccaacccgct gacctttatc ggattaagcg
     7141 gaataggcga tctagtcgtt acttgcacaa gtgttcattc taggaactgg cgcgcaggca
     7201 acttgttagg acaagggcag cccctagaag aggtgctagc caatatggga atggtcgttg
     7261 aaggtgtgaa tactacccaa gcagcgatgg aactagccca aatgatggaa atcgaaatgc
     7321 ccatcactca aacaatctat gaagtgctgt atgaacaaaa agaaatcaaa acagccgcaa
     7381 aagaaatcat gttacgtgat ggaaaaaaag aaaatgaatt ctcattaaca attttttgaa
     7441 ggagcgaatg tatatgaaag ttaaaaaagc agttattcca gcagcaggat taggaacaag
     7501 atttttacca gcaacaaaag ctatggcaaa ggaaatgttg ccaattgttg ataaaccaac
     7561 aatccagttc atcgttgaag aagcgttgaa atcaggtatc gaagacatct tgatcgttac
     7621 aggaaaagct aaacgaccaa tcgaagatca ctttgattca aatattgaat tagaaacaaa
     7681 cctaagtgaa aaaggaaaga ccgaattatt gaaattagta gaagaaacga cagatgtcaa
     7741 cttgcatttc atccgtcaat ctcatccaaa gggtttagga catgccgttc ttcaagcaag
     7801 agcctttatt ggaaatgaac catttgtcgt tatgctaggc gatgatataa tggaagacga
     7861 agtaccattg acacagcaat tgatcgatga ctatgagcgt acacacgctt ctacgattgc
     7921 cgttatgcaa gttcctcacg atgaaacttc aaaatacgga atcatcaacc caggggaagt
     7981 actggaagat gggttataca atgtcaaaaa ctttgttgaa aaaccagatc caagcaaagc
     8041 accaagtgat ttagctatta ttgggcgtta cttattgact ccagaaatct ttgatgtatt
     8101 atcagaacaa caaccaggtg ctggaaatga gatccaacta actgacgcaa tcgatacgtt
     8161 gaataaaaca caacgcgtat ttgcccgtaa attcacaggt aaacgttatg acgttggtga
     8221 caaatttggt tttatgaaaa caagtattga atatggtctg acacatccag aagtaggggc
     8281 acctttgcgt gaatacatca tgtctttagg taaaacatta gaagcagaag gaagcaagat
     8341 caatcataat ccaaaaggaa taacagaaat caaagaagaa aagaaaaaat aatctttttt
     8401 tctaacgagc ttcagctgct aattgaataa aaagtagttg aagctcgttt ttatttgttt
     8461 aaaaaacacg aaaatgctat ccttatagaa aagagagaca agaagggagt ttgatcatgt
     8521 caggaggaga aattgcagga ttgatcgcag caatcgcctt tgcgatactt gtcgttttca
     8581 tcgttcgcgt attgttgcaa gtttccaaaa ctttagaaaa agtagaccag actgtcgcag
     8641 aagcaaatac gacaattgag atcgtcacac aagacgtaga tcttttatct agacaagtag
     8701 aaggcttgct agtcaaaagt aatgagctgc tcttggatat caatggaaaa gtcgcaacga
     8761 tcgatccatt gttcacagca gttgctgatt taagtgaaag tgtatcggaa cttaatcatt
     8821 ctagtaaaaa catcgtgacg aaagtcggcg gaatcggaaa aacgacagct aaagcgactg
     8881 ttgccggaaa agtcggtgga acagcgatga aattttttaa aaacaaaaaa catactgaaa
     8941 cgacaggagg aaaataagaa tggctaaaaa aggtggattt ttattaggtg cagtagttgg
     9001 aggtacagcc gcagcaatcg ccgcattatt gttagcaccc aaatctggta aagaacttcg
     9061 ggatgaattg gctgctcaag cagatgattt gatggacatg gcttcagatt acacagatat
     9121 ggcaaaagaa aaatcatctg agttaacagg tattgcaaaa gaaaaagcgc aaggtctttc
     9181 tcaacaagca ggggatctag caggcaatgt taagcagaag gtaagtgaat cagcagagga
     9241 agcaggaagt gaatcagatg atatcttgtt aaacctcaaa gaacaatcag ctgatttatc
     9301 taatcgtttc aaaaaaacag cagaagatct gaaaaagcca gcagacgaat taggtagtat
     9361 tgctaaagat acttcagaag atatcatgat cgatgtaaaa gatgctgcag ataaagcagg
     9421 agagacggtc aatgaaggaa tgtcagaagc aaaaccagtt gcagatgaca caaaagaaat
     9481 gttgaaaatg gcaaaagaag atgcaaaaga agctaaaaaa gaaatgaaag atacaatgac
     9541 agattcgact accaatcact aagattactc atttctagaa taaaaaaggt gagagcggac
     9601 cagctctcac cttttttatt ttcattactc taaaacaagt aattcttttg gtgtagtcgt
     9661 gaatggcaca caaccatcac ttgtcacata cacacaatct tcgatacgta cccctacttt
     9721 ttcaggaata tagattcctg gttcaagaga gaagcacatc ccttcttcaa tcactaagtc
     9781 gtttccttct acaagagaag ggaattcgtg gacggttgtt ccgattccgt gacctaaacg
     9841 gtgattgaaa tattcgccgt agccatagct gttgatcacg tttcgtgcga tttgatcaag
     9901 ttcacctgct gtcacacctg ggcgaactgc ctcttgtgcg gcaagctgtg cttcaagagt
     9961 gatgttatag attttttctt ggaactcagt tggtttttga taagcaactg tacgagtagc
    10021 atcactgcaa tagccattcc aaataacgcc aagatcgaat aacactagtt catttggtga
    10081 aaccttcgtg cttcctggtg taccatgagg gcttgcagca tttgctcctg caaggactaa
    10141 tgtgtcgaaa gacatttgtg aaacaccttg tttttttaat tggtattcga tttctgcgat
    10201 aattgcttgt tcagttacgc cttcttttac tgttttgaag ccaatttcaa aggcaacatc
    10261 ggcccattta ccagcttcga tcagtttgtc tttttcttct accgttttga tcagttgcag
    10321 acgctggata atagaagtta gatcggtgta agaatctgta cctgtcaaga tatcagagat
    10381 agcatcgaag cgatcgacag tcagagcatt cttttcaata cctacattac caggttgccc
    10441 atagcgtgcg cgaagctctt ttccgatgat ctcccaagga ttttcgctgt ctaagtagcc
    10501 acgtacatcg tacgcccagc tgctgttttg agcatcttca acttccagag caggagtgaa
    10561 aaggaaagga tcttgttcca gagggataaa aagagctagt acacgctcgt gaggatcact
    10621 ttcatatccg gaaaagtaag cgatgtggcc agggtcgctg atataagcca attctacttg
    10681 gtgttgtgcc atccattgac gtagttcatt gatttttacg ttattcattt ggcaacctac
    10741 tttctaaatt aattttgtat tcaataattg taccactgat tgattaaaag accaacgttc
    10801 ttaaaactga aaaaagtaaa aattttcatg aaaacagaga taaaacggtt gcaattgttg
    10861 agattatttg atatcctatt ttagaaatgt aagacgtatt ttcagaaaac atataaaata
    10921 tgaataggag aacacaaatg gaaaagcaaa caatcactat ctatgatgta gcgagagagg
    10981 caaatgtttc gatggctact gtttcacgtg tcgtaaatgg caatccaaac gtcaaaccag
    11041 caacaagaaa aaaagtcttg gaagttatcg atcgcttgga ttatcgtcca aatgcagtcg
    11101 cacgtggctt ggcaagtaag aaaacaacaa cagttggggt aatcattcct gatgtcagca
    11161 atatgttctt tgcctcttta gcacgtggta tcgacgatgt ggcaacaatg tacaaataca
    11221 atatcatctt agcaaactca gatggcaacg atcaaaaaga agtcaatgta ttgaataatt
    11281 tattggctaa gcaagtggac ggcgtgatct ttatgggtca ccatatcaca gacgaaatcc
    11341 gtggagaatt ttcacgttca aaaacgcctg ttgtactagc tggttccatt gatccagatg
    11401 aacaagtagg tagcgtaaac attgattatg tgtcagcaac aaaagatgca gtaaataaat
    11461 tagcaaaaag cggcaataaa aaaatcgctt ttgtcagcgg tgcgctgatt gatcctatca
    11521 atggtcaaaa ccgtctaaaa ggctataaag aagcattaag cgaaaacaat ctaccatata
    11581 gcgaaggatt gatttttgag gcacaataca actttaaaga tggtctgtct ctagttgacc
    11641 ggatccataa tagcggtgca acagctgtct atgtttcaga cgatgaatta gccattggta
    11701 tcttggatgg tttattagac cgcggcgtaa aagtaccaga agaattcgaa atcatcacaa
    11761 gcaacaattc tttactgaca gaagtagctc gtcctcgttt gacaagtatc acacaaccat
    11821 tatacgattt aggagcggta tccatgcgcc tattgacgaa aatgatgaat aaagaagaag
    11881 tcgaagaaaa aacgattatc ttgccttatg gaatcgaaga aaaaggatca actaaataat
    11941 aaaagatcaa tcatttaaag gttgttccaa aagtggtcaa cttctggaac aacgtttata
    12001 cgagaaaggg ggttatgaca aaattttgtc ataacccctt tttttttgtg actttaaaaa
    12061 aagagaaaat ggcggaaaca aaccttacgt ccatcgtata cgacacaatc tgtgcgtaga
    12121 tgctacattt tgttcactac tatcaaaatt actttaaaat gaaaacgtga taaaaaagaa
    12181 agtagaaaag tagataagta actctaaaaa atccaaaaaa atccaggctc gattgcgtac
    12241 ttatcttaaa ggagaaacaa tccatcatat ataacccgaa aggagacttc tatttgccta
    12301 agaaaagacg aaagaccata gtcatcattt tgaccattct tactatagga atcggaggga
    12361 aattttacat ggacaaaaga gaaatgcaaa gacagaaaga tttactcgca gtagaaaaac
    12421 agtccgtcaa agttctgaaa aatacctttg cggatatcaa ggaagtgaag attgaaaaat
    12481 ctgctcgaaa tgaaatgacg ggttcatacc ggatagttat tctaatgact aataaacaag
    12541 atcaatcgat ttatttttct tatagttttt ggaaagaaag aaatgagata ggaagttacg
    12601 gaatagttga tgaaaaaaag caaaaagaag gaaatacgct caataaagtt aaagtaactt
    12661 actctaatgg aaatgaggaa agtatttaat gattactgac aaacaatata gtgaattaag
    12721 tgatgctgtt tactggctag atcctaaaca tagagactat gtacctgaaa tgcaagaaaa
    12781 tttaagtttt aaaattaacg gcactatgta taaaatccta aaaatcaaaa actccttcga
    12841 cggcatgcag gcgatggctg tagcgccaat cgtccatagc aaattggaga aaaatttcaa
    12901 aaataaaaaa attcctgcaa actttcgcgt acttaaataa tgaaggtgtc aatacttaca
    12961 taaaaagaaa ggaggcacgt tcttgtcaag gaaaataaga aaactcagct tagccatttt
    13021 attaatcgtc atattaggga tcggagggaa agtctatatg gacaaaagag aagcacaaag
    13081 gcagaaagat ttactcgcag tagaaaaaca gtcagtcaaa gttctgaaaa atacctttgc
    13141 ggatatcagg gaagtgaagg tagaagaatt taaaaaaaac cctgttaccg gaagttatgg
    13201 tgcacttgtg acaatgacaa ataatgaagg gaaatctgtt tattttgatt atagtttttg
    13261 gaaggagaga aatgaacttg gtggttttgg cattgagaac agagcggtac aaaagacagg
    13321 agtcactata aaaagagtaa aagtaatttt ttctaacgga caggaggagt tagtatgaca
    13381 ataaacgata agcattacaa tgatattagt gagaaggttt attggctaga tcccaaatat
    13441 ccccgctaca atgagggata caaaaagaac tctgttaaag aatttgctgg tatggaattt
    13501 caaatcctac aaatcaaaga ctcattggac ggcatgcagg cgatgtctgt agcgccaatc
    13561 aagaacggta aagtggatct ttctcaagta gtgattgctt ttgcaggaac gaacttaagt
    13621 gattggaaag atttggaaac ggatgcaaga agtatcatga atctctacgg gaatagacca
    13681 ggagcaagtt tttctgaaaa agcaacaaca aacaagattt tatccgttag tggattgaaa
    13741 acagcggggc aaatcaattc agcgattgca tttgctaatg aagtaaaaaa ggaatatgga
    13801 gaagctgcta tttctactac cggccattca ttaggtggat tcttagcatt atatgtagca
    13861 gcagagaaac aatggaaaaa tgtcggcttc aacgggccgg acccgtatga tctcttatca
    13921 ccagaagcaa aaaaatgggt ggaagaaaat cccggtatgc tcaccaatta ccgaaatcac
    13981 gccgatttta tcggtaattt tggtggtaat ggcacaggtg ctgaagttcg gatcagtatg
    14041 gaaacagcat tcttgaatct gcttgcttcc cacagtttaa cctcttggaa gtttgatgaa
    14101 aatggaaagc tgattattcc tgaaaatgaa aacaatgtta aagctcgaaa acaacagaaa
    14161 gaaaaccaag cgacccagtt gttttcctat cagttgcaag aactgaacaa catacgtaaa
    14221 aaactacgat taagtggcgg ccggctgaca gttaatgaac aaatttactt agatgacaca
    14281 caagctaggt tagtagtgga aaagttatcg gcaaaaatga aaagcgctat ggaagaagtt
    14341 atccgcatca atcaaagagg aatttttgag ctagagaaaa aatggcaaga aggcttgcgg
    14401 caagcacgtg ttgtagcccc ttcgttgact gaacaggaaa tcatagaagc attagctagt
    14461 gtgggcgcca caaaagaaaa cttagtcgat tctgcgaaag aagtctatct gctacgaatc
    14521 aataaggcaa gacgtatggg ggaggccttt gatacattgg cgaaggagat ccaagacaaa
    14581 atcaatgaaa tcgtggcacg agatcgagaa ttagcacagc aattcaatta aaggagaagt
    14641 agatgaaact agaagaattg gaaagagatt atcgaagtga acgaagacaa ttagaagctc
    14701 aagaagatga attgatccac tttaagaatc aaggattacg attgatggag caagaggagc
    14761 agcgactgca tcatgtatta aagaacttag ctttagataa tgagcctctg tttcaagcaa
    14821 gacgaagtta ttcgaattat caggagcatt atcaacaagc cctacaagta gaacgacgaa
    14881 aactctatca gcagcaagat gaactagaac gttcctatcg tcaaaaaatc agacaaataa
    14941 ctatggagaa atcatcttat gaatgaattt ttaatgcaat tactaaaaga attagagaaa
    15001 aatctacatc gatcaaatgt acgttcagtt ggtatgggga tatctcagca aatttgggca
    15061 gaaaaacgat tgacagatca aaactaccaa atgactgcag aagaagctgc tcaagaattt
    15121 tctaaccgac atgtacactt gaaaggatca gtaaaagggc aatttgcaga aaaactaact
    15181 gaattattcc aaagacaaga aaagaaatta aaacagtttc gttagtaaag ttatatagaa
    15241 aaattttgtg aaaat
//
LOCUS       DADLIO010000062        14995 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.065, whole genome shotgun sequence.
ACCESSION   DADLIO010000062 DADLIO010000000
VERSION     DADLIO010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14995
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.065"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            <1..608
                     /locus_tag="JOX41_002155"
     CDS             <1..608
                     /locus_tag="JOX41_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449875.1"
                     /translation="ENQLFAGDVLEIVLNDQAGEAAAKGVQNKPSTNDEIGNHNPSDT
                     PVVYHDAPPFAPATKIVVEGGLSFLAPSKLDCGQIKATGLTQEAFGQMDIQEKLWIYD
                     QRETKSPWILTIKLSQPFTTDAGFSMQDVLYFKKAEEYQLVNEEELEIVRGQNSTNVQ
                     TDYSEYLNNGRAFKLVLTKENQIAGNYSAEMTWTLADAPTE"
     gene            628..1656
                     /locus_tag="JOX41_002156"
     CDS             628..1656
                     /locus_tag="JOX41_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAY6449876.1"
                     /translation="MNRIWNKSHRNNCSLLLILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILIRNSEKESSPNLKLKKTYADQSDGRNVIKANLQNPNAS
                     YMFGLTTSVEIYKKETKEPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKG
                     AWKEKRWNLHTDFEITDDAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFI
                     LKERRKKK"
     gene            1653..2411
                     /locus_tag="JOX41_002157"
     CDS             1653..2411
                     /locus_tag="JOX41_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAY6449877.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPNEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QNGTDSTGTATQVQNFVQVTDKSGIYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGTPSTISGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEGKA"
     gene            complement(2497..3237)
                     /locus_tag="JOX41_002158"
     CDS             complement(2497..3237)
                     /locus_tag="JOX41_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAY6449878.1"
                     /translation="MKKYFIIEDNQFHSEWIIKELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            3298..4551
                     /locus_tag="JOX41_002159"
     CDS             3298..4551
                     /locus_tag="JOX41_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAY6449879.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGFIALMVVTLL
                     FPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGLRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            4852..5100
                     /locus_tag="JOX41_002160"
                     /pseudo
     CDS             4852..5100
                     /locus_tag="JOX41_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877177.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            5222..5548
                     /locus_tag="JOX41_002161"
     CDS             5222..5548
                     /locus_tag="JOX41_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAY6449880.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLQLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEF"
     gene            5616..6329
                     /locus_tag="JOX41_002162"
     CDS             5616..6329
                     /locus_tag="JOX41_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HAY6449881.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYLVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PIFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEEKEIVTLITCGDMDAVTRLVVQGELESVTP
                     IKDATDDMRSAFNLETKTF"
     gene            6639..7491
                     /locus_tag="JOX41_002163"
                     /pseudo
     CDS             6639..7491
                     /locus_tag="JOX41_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            7612..9477
                     /locus_tag="JOX41_002164"
     CDS             7612..9477
                     /locus_tag="JOX41_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAY6449882.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            9525..10934
                     /locus_tag="JOX41_002165"
     CDS             9525..10934
                     /locus_tag="JOX41_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HAY6449883.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            11042..11743
                     /locus_tag="JOX41_002166"
     CDS             11042..11743
                     /locus_tag="JOX41_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAY6449884.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            11902..12381
                     /locus_tag="JOX41_002167"
                     /pseudo
     CDS             11902..12381
                     /locus_tag="JOX41_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015510350.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            13229..13804
                     /locus_tag="JOX41_002168"
     CDS             13229..13804
                     /locus_tag="JOX41_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HAY6449885.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            13804..14244
                     /locus_tag="JOX41_002169"
     CDS             13804..14244
                     /locus_tag="JOX41_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HAY6449886.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            14260..14961
                     /locus_tag="JOX41_002170"
     CDS             14260..14961
                     /locus_tag="JOX41_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAY6449887.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
BASE COUNT         5067 a         2485 c         3161 g         4282 t
ORIGIN      
        1 cagaaaatca actttttgca ggagatgtat tagaaattgt attaaacgac caagcaggag
       61 aagctgctgc taagggtgtg cagaacaagc caagtaccaa cgatgaaatt gggaatcaca
      121 atccaagtga tacgccagtt gtttatcatg atgccccgcc ttttgcacct gctacgaaga
      181 ttgtagtaga aggtggtctc tcatttcttg ccccttccaa actcgattgt ggtcagatca
      241 aagcaactgg gttgacgcaa gaagcatttg gccaaatgga tatacaggaa aaattatgga
      301 tttatgatca gcgagaaaca aaaagtccat ggatcttaac gataaaatta tctcagcctt
      361 tcacaaccga tgcaggattt tctatgcagg atgtcctata tttcaagaaa gctgaggagt
      421 atcaattagt gaatgaagaa gaactggaaa ttgtcagagg acaaaattca acgaatgtgc
      481 aaacagatta ttcagaatat ttaaataatg gtcgggcgtt taaacttgtc ttaaccaaag
      541 aaaatcagat agctggtaat tactcagcag agatgacatg gacattagca gatgcgccga
      601 cagaataaag atcaaggaga atgattgatg aatcgaatat ggaataaaag tcatcgaaac
      661 aactgctctt tacttctgat ccttctcctt ggattcatcc tttggcagac acctgtccat
      721 gcctccgaat tcaattttgc ggtagatttt gaattaccgg ctaatcagat tgataagaac
      781 aaaacatata taaatgtaag gatggagcct gggaaaacac aggaaatccc ctacacggtc
      841 tttaaccgaa cagataaatc agtaacagtt gagacattga tccactccgc tacgacgaat
      901 tcaaacggtg tgatcgaata tggagaatca aaaagtaaat ttgatgaaac attaagttat
      961 gatatgaaaa acttagcaaa aacagtggga gaaataactg tccctcctca aagtgcggtc
     1021 actgagacac tttcactgaa agctccagaa aaagagctgg ctggtgtggt cgcaggagga
     1081 atcacgtttc aagaaaaaaa agagaacgtt tctaacaaaa gtacagttgg tgtcgtcaat
     1141 cagttttctc aagtgaaagc aatcttgatt cgaaatagcg aaaaagagtc ttccccaaat
     1201 ttgaaattaa aaaaaactta tgcggatcaa agcgatggaa gaaatgtgat taaggcgaat
     1261 cttcaaaatc caaatgcttc ttatatgttc ggcttgacta catcggttga aatctacaaa
     1321 aaagaaacaa aagagcctta tctttcaata aaaaaagaaa aaatagatgt agcacccaat
     1381 acaaattttg atttacttgt cccattagaa ggaaaaaaat tagctccggg acattatcaa
     1441 gcggttgtga agggtgcttg gaaagaaaaa cgctggaatc tccataccga ttttgaaata
     1501 actgatgatg cagcggacca attgaatgaa aaggatattg atttaaaaaa tcagccagaa
     1561 acatttgact ggcgatggct gatacttgtt ggagtcattc ttattggctt atttgctgga
     1621 ttatttattt taaaagaaag aaggaaaaag aaatgaaaaa aacaattgca ttaagtaccg
     1681 ttctagctgg aagtctatta ttatgtacac aaagtgtttt tgctgagaat aagagctcag
     1741 ccactacaga aggaacgatt tctgtaacaa aaccagatgc cgcaaatcct gaagacgttg
     1801 ttccagttcc tcctgttgat ccaaatgatc ccgatacgcc gtttacacct aacgaaccaa
     1861 atcagggaac atccggatta ctgacgattg accaagctcc agatcttgat tttggaacaa
     1921 tcaagttagg tacagcaaaa acagtatatg ctgcattaca aaacggaacg gacagtacag
     1981 ggacagcaac acaagtacag aatttcgtac aagtaacgga taaaagcgga atttatgccg
     2041 gttggaaact atcagtcaaa cgaacagaat ttattggtac aacatctgat acgaataaac
     2101 taactggttc aaaggtgaaa ttcaaaaacg ccgtgattcg aaatagcgca actaatagca
     2161 gtggaacgcc atctactatt tctggtactg gcgctgaagg aattgagatc ccagcagatc
     2221 aggcagtaga tctagtaact gcaggagcaa atgaagggat tggcacatgg atttattcat
     2281 taggagagaa tgtggaacaa gggagacaat cagtggaatt atttgttcct gtatccaatt
     2341 atgccgtaga caactacgtt tcaacattca catggtcgtt aacagatgct cctacagaag
     2401 ggaaagcgta aaatcaaatc aatgacttca gggagtggag ccgattcaag gccaactccc
     2461 tgaaatctgc tatgcttacg tctcagctct tattcatcaa ctcgaagcag ttttttggaa
     2521 gtcatggaaa cgttcctttg tcttttcaaa gatctttcga ccaacgagta aggagtcacc
     2581 attgaaaaat tctaacacat aatgagcaga atcaattttc tgcaattgcg ataagttgat
     2641 acagtaagat tttaatagta aaaagtaagc atacttttcc aactctgtct tcaattgttt
     2701 taaagaagta ttcactaatt tatcttctgt agttgttttg accataactt ggtttttcaa
     2761 acctttgata ctttcaatat ataaaatttc ccgaggatac aggacgagac ttccaccttt
     2821 ttgatcaata aagattttat cgacatttac gatttgctgt tctttccaat tgatctgttc
     2881 tagcacttga cgaatttgtt cagataaatt cctgtctttt ctgatatatc caatcggaag
     2941 gattttccga ttgatgatct ctactgcaaa attcgtataa gcggtgaaaa aaacaatatt
     3001 actatgtgca ttttttttac gtatttgttc ggcgacatca atacctgtga gtgattgctt
     3061 caagtcgata tcgataaaga aaacatcgtg attatcaata gtacccaact ggatcaactg
     3121 attgatttga gagatagaag tgagctgcac gatattctcg atatgatgat tgaccaattc
     3181 tttgatgatc cattcgctgt gaaactggtt atcttctatg ataaaatact ttttcatatg
     3241 caggctccta ttaaaaaaat atgtgtacat tttgaaacaa aacaatggag gaataagatg
     3301 gtcgcaacag tgacacttta tttgaccttt actttgattt tagatttagg tatctattta
     3361 ttcttttcga aacaactgct agtaaaaaac agctttggtt ttatagcttt gatggtggtg
     3421 acacttttat ttcctatccc taaagtgagc tttccttacc tagttggctt attattgatg
     3481 tttctttttt attttactac gaaaaacctg tttatcagct gtttgatcag taatcttttt
     3541 tttgctatca ctggactcag cttttttctg gtttttgatc tgatggatta tttaggaaag
     3601 agacatcttg gaacagcaag tttttttgca ctacttatcg catttatttt ctatctatta
     3661 gtaaaaagta tagacaaaca gacgagattt ctcaacttgc tttttactta tccaactgaa
     3721 cactattttg gaggtatttg tattttatta agctggggcg tgatttactt ggtattggga
     3781 agtgttcact tccgctcatc taattatctg cttctatctc ttttgtcgat agtcatcagt
     3841 tttttttctt tgtttttttc cattatgttg atcagtttcc aagtaaaaga aagacaacat
     3901 caggaatcgc ttcaactgta tcaaataaat gaagaatatt accatcatct agaggaattc
     3961 aaacatgatt ataaaagtct actgttttca ttaaaaatta ctcttcagga aaataaaaaa
     4021 gaaacgttgg aatttttaga aatcttagaa gatcattctg cagctatttt tgaaaaaccg
     4081 caaatacaac agctaacaaa tattgtatcc ccagctgtca ggggtgtctt tttaaaattt
     4141 ctagaaaaag cagaatcgga gaaaatcccg atccaagtag ttattcctgt cgaagtgaaa
     4201 acaatcccga ttgatctggt tgtttttatt cgctgtttat ctatttttat ttctaacgca
     4261 ttcgatcatc gtgtagccga tcagagtccg attacgatca atctgctgga agaaaaagag
     4321 ggattacgtt ttagtatagc gaacaaggca aatccgacga atttgacgct atcggagatg
     4381 gtcaaaagag gaaaaacctc taaaaaaaat ggcgggttag gtctatacag tgcgaaaaaa
     4441 atgttggatg tttacgaaaa tgcagaacta aaaatcgaat tttcaaaaca gaatcactat
     4501 ttttttgtag aaatgtatct ggcatctaga aagagcaaat cagcctactg acttactgtc
     4561 aaaggataag cttgaggaaa gtctacacgg agatagagac aacaacacag catattcaaa
     4621 agaaacagaa gcgtgatgac cgttgtcacc cttctgtttc ttttgctatg tagttaaaca
     4681 aagtagttga cacttccgct acttagtatt agtacgaaag tatacttcat gatactaagt
     4741 agataagaag tgaaaagcgg aacccacgat cgtcaaaatg ctaactgctt tgcttacacc
     4801 agataaaggg aagagcaata tcgcttattt taggcgtgga gaagcaagaa aatccctacg
     4861 atcacacaaa aaatgctgac ccagcagtta agagagttag aacaagatgg cattgtccat
     4921 cgaaaagtct ataaccaagt cccgcctaaa gtagagtact cgctcaccga agaaggaaaa
     4981 tcattaagag agattctagt agcgatgtct gtttggggag aagaacgtat cgaaaaacaa
     5041 aaagcctcag gggaagaagt cacattactg catacacatg gtggctacct aaattactga
     5101 tttctatgac atttatttta aataaaagaa aacaggagtt tttttaaaag catcatctat
     5161 tttttatgta aaaaaatggt atgattaatc aagtaagaaa tgattggaag aaggcaagca
     5221 aatgaatagc atggaaaaag ttaaccagtt tagagatgaa cgtaattggc gacaatttca
     5281 taacgaaaaa gatttggcta tttctatttc tttggaagca tctgaattgt tagaactttt
     5341 tcaatggaaa acgccggaag aagtaaaaga aacacaatta gaacgaatca aagaagaact
     5401 ggcggatgta ttgatctatt catacatgat ggcagacaac cttcagctgg atctagatga
     5461 gatcattgaa gaaaaattga tcaaaaataa tttgaaatat cctgtagaaa aaagcgcagg
     5521 tgtacgaaaa aaatacacag agttttagaa atgtgtcatt cggctgttgg aaagagcaaa
     5581 agaaaaacag taaaatgagt ctggagggag agaaaatgaa aaaaaaagga aaagcaaaaa
     5641 gatggctagt caatatcctc ttgttcctct tgttattagt aggactagct ttgattttca
     5701 atgaacagat caaggattat cttgtcagag agacaggaga taaatatgct atagcgaatg
     5761 taacaaaaga agatctgaaa aagaataacg ataaagatgt cagttttgac tttgatgcgg
     5821 tagaaccaat gacgacagaa ggggtcatga ggtcgcagat gagaggaaca gatctaccag
     5881 tgattgctag tatcgcagtc ccttcagttt caatcaattt accgattttc aaaggcttgg
     5941 ataatacgtc actactttac ggagcaggaa cattatctcc agatcaagaa atgggaaaag
     6001 gaaattatgc cttagcaagc catcgtgcaa cgaaccctga attgttgttt acaccgctgg
     6061 aaaatttaga gatgggtgcc aagatctatt tgacagattt agaaaatgtg tatacataca
     6121 aaacattttt taaagaaaaa gttgctccta cagataccca attactgaat gaagtcgagg
     6181 aaaaagaaat tgtcacacta attacttgtg gcgacatgga cgccgtcacg cgactagttg
     6241 tacaaggaga actggaaagt gttacaccga taaaagatgc gacagatgat atgagatctg
     6301 ctttcaatct agagacaaaa acattttagg atactgggac ataagtcgtt acagattaaa
     6361 aacagccaaa ggatatgaat cgataaggaa aaaccaattt gctgaaaaaa agaggaacgc
     6421 aaagaggtgc atctctgatt tggttgtttt ctagatagac ttgtgttcca gtttttttat
     6481 tttttatatg aaaaggcttg cataaataaa aattcgatgg tatgatgatt ttgaataaga
     6541 aatggattgt tactgtacgg caggcaaaac cagaattcag ctaagaaaca gtaggcgaat
     6601 tctaggtttt tttatttttc ttgagagggc gaagcaaaat gaaaattgat aaaattttga
     6661 ataacaatgt cgtcatttcg aaaaatggat tcggggaaga agtcgtttgt atgggaaaag
     6721 gactagcttt tcaaaaaaaa gattggggac gagatttcgc cagaagcggt ccaaaaagaa
     6781 tttattttaa gagattcttt tgctaaaaac caattccagc agctgatggc tgatattccg
     6841 gcagaggaga tcgaatgggt caaacaagta gtcgaactgg ctgaagataa actaaaagtt
     6901 gaattttcgc ctaatattta tctgacattg accgatcatc ttcattatgc gatcacacga
     6961 gcaaaagaaa atatccaact gcctaatcca ttattatttg aaacaaaaaa attttatccg
     7021 aaagaatatc aagcagcgaa agaggctctt ttgttcgtga aacaaaagac gggtgtggaa
     7081 ctttctgagg atgaagccgg ttttattgcc tttcattttg tgaatagcca acaaggaaac
     7141 gaagacatgc aagtgacgat gaccgctacc acaatggtaa gagatatact gagtatcatc
     7201 agtaaattct tcggcatcgt gttcgatgaa gaatctttga attatcagcg tatcattact
     7261 catctgcagt tttttgccca gcgttatctc aaaggggaag gatctgacga gcaagatgaa
     7321 tttctctacg cattagttca aggaaagtat ccaaaagcgt ttcattgtgt cgaacggatc
     7381 aatgagtatc ttcgacaaac gcaaaaacag gaaatgggga tcgcagagca gatttattta
     7441 acgattcata ttcaaagagt agtaagtgag aaaaaaagca tccaatcata aggattgtta
     7501 ctgtatggca ggcaaaacct ggattgaaaa aataggttca cgaatgtttg tgactgtttt
     7561 tttcaatctg ggtttttatt ttttaaataa aaaagaaaga aggaaaaaac aatggataat
     7621 caagcagttg gtcgtcgtgt atgggaagcg gtaggaggac aaaagaatgt caaaagttta
     7681 gtacattgtg ctacgcggtt gcgattcaga ttaaaagatg aatctttagc agatacgcaa
     7741 aagttaaaag aagacccgga cgtgatccaa gtcgtacaaa gtggcggtca gtatcaagta
     7801 gtgattggca gtaatgtagc agatgtttat caatcgatcg tggatgagga aggtcttgca
     7861 gtttcggagg atggaaaaga agagtccaaa aatattttga atcgtctgat cgatattatc
     7921 tctagtatat ttacaccttt tctaggggcg atggcagccg ccggggtatt gaaaggattc
     7981 ttatcattgg caacggtgat gggctggctg acagctgata gcggtactta tcaaatattg
     8041 tttgctgcag cagatggtgt ctttaccttc ttacctgtca tgcttgcttt tacagcagct
     8101 aaaaagttca aagccaacca gtttttagca gtagcaattg ctatggcact tgtgtatcca
     8161 gctatcacag cagttgctgg tgcgggagaa gctatcagtt tctttgggat cccagtgatt
     8221 ctttcaccat ctggttatac ttcttctgtc ataccaatca ttctagccgt atgggttcaa
     8281 agtaaattag agccattcgt aaaaaaagtg attccgcaat ttctgcaaat gattttagtt
     8341 ccgcttgtcg ttttagtagt gatggttcca ttaacatttc ttgctttagg accaatcggg
     8401 acggttgccg gtaatgcttt aggcggtctc ttcaactcga tttatggatt tagtccaatc
     8461 gtagcaggtc taatcatggg aagtttatgg caagtattcg tgatgttcgg catgcattgg
     8521 ggattcgtac cgatcatgtt tttgaatatc gaacaatatg ggtttgatgt attgatgcca
     8581 atgcttcttc cagccatctt ggcacaaggt ggggctgctt tagctgtagc attgcgaaca
     8641 aaagatacga aacttcgagc attagggatt tcttctacag tgacttcgtt atttggaatc
     8701 actgaaccaa ctgtgtatgg tgtgacatta cctttgaaga aaccattcat tgccgcttgt
     8761 atttctggag gtattggtgg agctattatc ggattttccg gagtaaaagc tttctccagc
     8821 agtttggtca gcttattgac gattccgact ttcattaata cggtggatgg tgtagagtca
     8881 aatgtgacag tagcagtaat agctacagga attgcttttg ttcttgcatt cgtaggtaca
     8941 ttgattttag gatttgacga acaaacacaa gacaatcaat tagaaaacaa acatgcgaat
     9001 gcaggagaac cgattacttc agcacggcat accttaaaaa gtcctttaac gggtaaagta
     9061 ctgccattga gtgaagtacc agaccaagtt ttttcttctg gcgtgatggg aaaaggtatc
     9121 gctattgatc cagaagtagg agaactagtt gcacctgcag acggagagat cacgactatt
     9181 tttccaactg gacatgctgt agggatcaca acgactgacg gagcggagat tttgattcat
     9241 atcgggatgg atacagtaga attaaatggg aatggctttg agatcttagt caaacaaggg
     9301 gatctcgtca aagcaggaga tttattgatt cgttttgaca tcgaagcaat tagagcagct
     9361 ggctatagcg taatcactcc agttgtcatt acgaatactg atgcatttgc cgatatactt
     9421 gaattagacc aaaaagagat tattgcaaac gaagatgttc tggcaattgt aaaataagga
     9481 ggaaatcagg atgcaatcac gtttttcaga aaaattttta tggggtggag caactgctgc
     9541 caaatcaatt agaaggggct tatgatcgag acggaaaagg actatccgtt gcagatgcta
     9601 tgcctggagg taagcagcgc tttgcgatta tcggcagtga agaatttgac tggacgattg
     9661 atcaagaaaa atatatttac ccgaatcatc gaggaatcga tcattacgat cgtttcaaag
     9721 aagatcttgc cttgtttgcg gaaatgggat tcaaatgtta tcgtttttcg attgcctgga
     9781 cacgaatttt tccaaatgga gacgaaggta ctcctaacga agcgggatta gaattttatg
     9841 atcagctgat tgatgagtgc ttaaaatatg atattgaacc tgtgatcacg atttctcatt
     9901 acgaaatgcc tcttcatttg gcaaaagaat acggtggctg gaaaaatcga aaactgatcg
     9961 acttctatga acgatttgct cagacagtat tagagagata cagcagtaaa gtcaaatatt
    10021 ggatgacttt caatgaaatc aattcggcct ttcactttcc agctttaagt caaggattag
    10081 taaaaagcaa tggagcagga gagtaccaaa atattttcca agcatggcat aatcaattcg
    10141 ttgcaagtag caaagccgta aaaatcggcc acgaattgcg ttcggatatc caaatcggct
    10201 gcatgattat ctatgcaaca acttacagca tcgatgccaa tccagtcaat caggcagcaa
    10261 caatgatcca aaaccaagaa ttcaattttt tctgcacgga tgtccaagta cgtggagaat
    10321 accctgcata cacagcgcgt acccataaaa aatatggagt cgatccggaa aaattagagc
    10381 aaacggaaaa agacttccag ttgctaaaag aatatccagt ggactacatc ggatttagtt
    10441 attatatgtc tacggcaatc aatgagactg atccacaagc agcaacttca gaagggaact
    10501 tgctgggagg agtaaaaaat ccgtttcttg aggcaagtga atggggctgg cagatcgatc
    10561 cagaagggct gagaatcgca ttgaatgaat tatacaatcg ttaccagaaa ccattattca
    10621 ttgttgaaaa cggtcttgga gccattgatc atatggaaga ggatggcacg attattgatg
    10681 attatcggat cgattattta cgtcgtcata tcgaagcgat ggctaatgca gtagcagacg
    10741 gtgtagattt gatgggctat acgccttggg gatgtatcga tcttgtcagt gcatcaacag
    10801 gagaaatgag taaacgttac ggctttatct atgtggatct agacgatgaa ggaaatggga
    10861 cactgaatcg atcaaagaaa aaatcttttg attggtataa agaagtaatt gcctcaaatg
    10921 gcgtaaactt gtaattaaag cagctgaatg aaaaagaaca cacttctcac atgtgatttg
    10981 tgttcttttt ttatttttta tgtgctattc ttttagtaat agtaaagcaa agggtgacgt
    11041 tatgaaaagg acacgtgtac tatacttgga agtcgcagat aaaattaaag aagatatttt
    11101 ctcaggaaaa tatccagtcg gttcgatgtt gccgacagaa agtgaattag aagaactgtt
    11161 tcaagtcagc aaaatcactg tccgaaaggc aatcgaactg ctggcatcag atgaatatgt
    11221 cgcaaagaaa agtggtcgtg ggacgacggt tctaagcaat cgtccttaca atcgattatc
    11281 caaagcggca agctttacgc aaatcttgga gaactcccga tatgaagtcc ggaaagaaac
    11341 gctggatttg caattggtcc atataaagaa ggaagatcct ttgttttcct ttttcggtga
    11401 gcaagctgtt tgttttaagc gcttatatta tttgaacaat cagccttata tttattttgt
    11461 tcattatctt ccacaagaaa tgatgcaatt cagcagagaa gaatttggca aagaatcttt
    11521 gtatcgtttg ctgacgaaaa aaggatatac tattgactca ttttctgatg atttctcggc
    11581 agtattttta acagaagaag aacaaggaat tctgaaaaca gacgcacaga tcggcatcaa
    11641 acggatacgg aaatcgtcta cgcaaattgg ggaaatgatt gaatattcgg aggcggtcta
    11701 ccatacggag ctgcatcctt accatattga ttatgaaaca taaataaaaa aagaggttgt
    11761 gaaaaagctg ccctgcatca agtaataaga acagccaaac aaaaatagct tctcatattt
    11821 ttcgtttggt taggcttatt accgcagata cacggctgtt tctggattac catttattct
    11881 ggataagggg gtgtggcacg attttcagaa ggaatctatg aaccaatcac tgtattgatt
    11941 ttagcttcga tggtaacccc attcggcttg acgatcgctt atttcttagg gaaaatcatt
    12001 cgtaaaaata tactcaatcg tcaagaaatc gatacattga agaccgcttt tcctatgggg
    12061 atctgtcaga tcacagaggg atgtttccct atcgtattga acgacttggc acgcaatgtc
    12121 atagcaacgg gagtcggtgg gacagtaggt ggcggattaa gcatgttttg gggcgcagat
    12181 agccgtattc cggcatcggg aatgtttgca gtcgctacga tgaccagacc atgggcattc
    12241 attggtgcat tgttagctgg ttcttttgtc acaggaataa ccattttatt attgaaaaaa
    12301 ccagtagatc cgaatgcaga aatcatccaa gaagaaaaag aggaagaaga catatcttgg
    12361 gatgatttga caattagtta ggagaggcag aatggattac aagaaaaaag tacaatagat
    12421 gtaccttgag acaggaatgg tatgaaagaa tcagagttag aaagaatcga atatacagat
    12481 tttggtttag gagcgatcga aactgtccag agcatcggca ccctccttga aatgacgatg
    12541 aaggaaaaat gagaaccttt cgttgtcgaa agggtctggt ataccttatg tcgaaggaaa
    12601 ggaaacaaaa aaactttcct gtactattcc aaaaaggaaa gaaagttatt atacagtaaa
    12661 aaaagaaatt attcttcatg ctagagatca gtacacgttc gagcccaata tcaaacacta
    12721 gttccaggca ggcgcaacag gtgcggttat cactgaattt tcttccagca gtgacgattc
    12781 aagtgatatt tttacaaatc cagctattta tcgttaacaa aaagattttt aggagaagct
    12841 gatgaacaaa aatgatcaaa ttttgatcgt ttagttcgtc ggctttttta tttagagaaa
    12901 catcatttat cagtgaaaca taacacgaga acaaaatgat tttttcgtta ataaaagaaa
    12961 caagtatttg ttgtttaaaa taatacacgt tattggcata taggacgaaa tcccagtatc
    13021 ttctataagt aagtcatttc atatcgatga aaacacgtta tttatttttg ttttatctat
    13081 aaaatggctg aaaaatgatt tttttctaaa tactatatat agtggcgtct atcctatata
    13141 ccactaaaaa actacaaaat ctagtctttt attttaaaaa aacacgtgta gaatgaagat
    13201 agacttttga gttagggagt gtttttttat gaaacttact gttttttgcg gttcccgttt
    13261 tggtaataaa gaaagttaca aatttattgc gcaaacgtta ggaaaataca tggcacaaga
    13321 agaaatcgaa ctggtttacg gtggttcata ctccgggatt atgggagtga ttagtaaaac
    13381 agtactggaa aataacggaa aagtcacagg tatctatccg aatgggcttt ttgaaactga
    13441 attgcctgga aaagatgtta ctacatttat tcctacagaa acgatcgatg aaagaaaggt
    13501 attattattt gaaaagggag atgctgtcct cgttttccct ggaggtctag gtacattgga
    13561 ggaattctca caacttcttt cttggatagc aatcggtctg acgcccgaca agccaatcgg
    13621 aatattgaat attggcggtt attacagcgg cttgcaacaa ttattagaaa cttttgcaaa
    13681 agaggatttt atggataaaa aatggttgga tcaagtaatc ttttccaaca atccattgga
    13741 actggtcaat gaattacgag cagtatctat taaaaatcag ttattattga aggaggcaaa
    13801 ataatgagtc aaatatattt agcaggacca tttttttcag aggagcaaat cgatcgagta
    13861 agtcgtatcg aaaaagcgtt ggaggaaaac aaaacagtca caagtttcta ctctccacgt
    13921 catcaccaag aaagcaatta tgaactattc agcgctggat gggcgcagga agtatacgaa
    13981 aaagatatgg aagaactgac aaatgcagaa tttgttgttg ctatccttga ctttgagcat
    14041 caaacaatcg atccaggaac ggcttacgaa ttaggtgtgg caactatgtt gaaaaaaccg
    14101 atgatcattg tacaagaaga gacggtacct acgaacttga tgattacaca aagtctccat
    14161 acgtatttaa aatcagacca agctgtacgt gaatatgatt ttgaaacatt gcctgttgaa
    14221 acttacgtag gcgagtactt atagaagagg aagggttgta tgtcagtgat tttgatttca
    14281 ggaacgattg gtgcaggtaa gagcagtttg acggatatgc ttgcaaaaga gattgattct
    14341 aaaccatttt atgaaaatgt cgaagataac gaagtattgc cgctctttta ttcaaatcct
    14401 gagcagtacg cttttttatt gcaaatcttc tttttgaaca agcgattttt agcaatgaaa
    14461 aatgctttag tgaacgatga caatgtgcta gaccgatcca tctatgaaga tagcctgttg
    14521 ttccatctaa acgctgattt aggtcgggta acggatatcg aagtacagca gtacgatagc
    14581 ttattagata cgatgctaaa cgagttagat gatgttgctc caaaaaaacg gcctgatttg
    14641 atggtccata tcaaagtttc tttggacacg atgctagaac gtatcaaaaa acgtgggcgt
    14701 gactatgaac agctagaaag cgatgagacg ttatatacct attatgaaac gttgaacacc
    14761 cgctataatc aatggtatga agattttgat gtatgtccta aaatacaagt ggatggggat
    14821 aaattcgatt ttgtagaaaa tccagaagat gcaaaaaagg tgatccgtca gatccaagaa
    14881 aaattagctg aattggaagg aaagcctgct ggaaaatatt ttacggataa ccagcatgca
    14941 aaaggtcaag aattaggcta aaaataaaaa accaaacgac gggaaagaaa aatta
//
LOCUS       DADLIO010000063        14812 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.066, whole genome shotgun sequence.
ACCESSION   DADLIO010000063 DADLIO010000000
VERSION     DADLIO010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14812
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.066"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(606..1172)
                     /locus_tag="JOX41_002171"
     CDS             complement(606..1172)
                     /locus_tag="JOX41_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAY6449888.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1172..2128)
                     /locus_tag="JOX41_002172"
     CDS             complement(1172..2128)
                     /locus_tag="JOX41_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HAY6449889.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2128..2784)
                     /locus_tag="JOX41_002173"
     CDS             complement(2128..2784)
                     /locus_tag="JOX41_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAY6449890.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3154..5172
                     /locus_tag="JOX41_002174"
     CDS             3154..5172
                     /locus_tag="JOX41_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAY6449891.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     gene            5599..8013
                     /locus_tag="JOX41_002175"
     CDS             5599..8013
                     /locus_tag="JOX41_002175"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016183651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HAY6449892.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8361..9914
                     /locus_tag="JOX41_002176"
     CDS             8361..9914
                     /locus_tag="JOX41_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HAY6449893.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10295..12079)
                     /locus_tag="JOX41_002177"
     CDS             complement(10295..12079)
                     /locus_tag="JOX41_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6449894.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12094..13815)
                     /locus_tag="JOX41_002178"
     CDS             complement(12094..13815)
                     /locus_tag="JOX41_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6449895.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            13915..14676
                     /locus_tag="JOX41_002179"
     CDS             13915..14676
                     /locus_tag="JOX41_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAY6449896.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
BASE COUNT         4804 a         2739 c         2927 g         4342 t
ORIGIN      
        1 ccttcagaga atactgtttc tttttttgca gttacaggtt gtttattttc ggaaaaagct
       61 aatatagcta aaattgaaac atccatctgg aatttatctt ttttactgct ttgatcataa
      121 aagtctgcat attcatcact gatatttttt ctaataaatt cttccatcat aaaaatcacc
      181 tcaaaacgat tatacgaact tacgttcttg ttgtaaagcg atatttgagg ggcaaaaaag
      241 gggcataatt tgactgatat taagttagct attgatatat gaatgacata caaaaatata
      301 aaatctttta aaaatgctta tatatcaatg tttttgccat tcttttatat atctgttata
      361 tgtcaaaaaa atgtgttcaa tttcaatttg tatttgaata aagaggttgt gaaaaagctg
      421 tcctgcatca agtaataaga acagccaatc aaaaacagct tctcatgttt ttgatttggt
      481 tggacttatt accgcagata taagcttttg agcaccgtga ataaagaggt tatgaaatca
      541 acgctctaac ctgagtatta gagaaaaaaa cgcaaaacat atcatttatg ttttgcgttt
      601 tttatttatc tttttttctc aatacaatat aaaataggcg gctggttctt ttggttgata
      661 aaccgataat tcagcacatt atatgtttcc tgtggcagtt tggaacaaaa agaatcaacc
      721 atatccagtt ctttttctcc accttcatga ccatagtaga cgacaaggat caatcgtccg
      781 cgaggcacaa gtcgtttcaa tatttcttcc atagctgtgc gtgtagtctc tggcatagtg
      841 atgattgctt tatcactttt tgggagatac cctagattga aaatccctgc tttgagattt
      901 tgttgttcag ctatcacttc tcctaacgtt tcgtggcctt gtagaaacaa tgagacacgt
      961 tcttctaact gacgctgttc tagcctttca cgagtagcat cgattgcttg ttgctggata
     1021 tcaaaactat agacatgacc agtttttccg atgtgttctg ctagaaaaac cgtatcgtgg
     1081 ccattgccca tcgttgcatc tacgacgtga tcccctggtt gcaagatttc ttgcagtaat
     1141 gtatggctga aatgcaaagc agtttgcaac atcagacgct cacctttttc cgtacatcat
     1201 attttccttg gaagctatct ctgcgaagaa gttcttcatc aattgcattc aagacttccc
     1261 attttttcaa gctccacatt ggtccaatca aggaatccca cggcgcatcc cctgtcaaac
     1321 gatggatgat gatctctttt ggtatcattt ccagctggtc gcaaatgaca ttgacatagt
     1381 caggacggct cattaattga aggcgacctt catgatagtc ccgcaacatt ctcgttttgc
     1441 gcatcagatg catcaaatgg agcttgattc cttggatatc tgaatctaaa atggtgcgtc
     1501 tgacattttc tttcatcatt tctaaacttt cgcctggtaa tccgttgatc aaatgcgtac
     1561 aaacacggat attatgtttg cgtaatttag ccacgccatc taaataagtt tgataatcat
     1621 gtgctcggtt gatcagtttt gaagtttctt caaaagttgt ttgcaatcca agttctaccc
     1681 ataaatacat ccgctcgttc agttcagcaa ggtaatcaac tacttcatct ggcagacaat
     1741 ccggtcgtgt accgactgat aatcctacga cacctggtaa attgactact tgctcaaatc
     1801 gttctttgat tatttcaact ggcgcatggg tgtttgtaaa attttggaaa taaacgatgt
     1861 attgttggac atgaggccat ttttgatgca tcatgtcgat ttctttctgg aattggattg
     1921 gaagagggtc ttcaggtgca acgatcatgt ctcccgaacc agatacactg caaaaagtac
     1981 aaccgccatg ggcaacagtc ccatctcgat tcggacagtc aaatcctcca tcgatcggca
     2041 ccttgaaaat tttcccgcca aactcatttc gtaaagcgta attccaagaa tgatatcttt
     2101 tatttccttc tgaataagga aaagtcatta aaagtccttc tttctgtaag agttatctat
     2161 ttgttttctt ttttctctat acactggata agtcaggcac agccaagaaa gactgagtaa
     2221 gtaaccgccg atgatatcag taggaaaatg aacgcccaga taaatgcggc ttatcccgac
     2281 acttactata ataaacatca tcagcaattg aagcaatgtg cgtaaggttc ttttttgaac
     2341 aaaagctgga agcagaaata gtaaagaacc gtaaagaatc atactgcctg ctgcatgtcc
     2401 actagggaaa ctgtaacttg tttcaactac taagtgcgcc aatgaaggac gctctcgcat
     2461 gaaaaatagt ttgatcaccg ggttgatgat tccagcaatt acaataaatc cagaaacgaa
     2521 ccaaaatgtt tctgcccttt ttttcttata ccacatccat aaagccgcac aagcaaataa
     2581 aatgatgacg gtaagaggat taccgaattt agtcataaag agttggtagc tgttcagatc
     2641 aggataagaa gctctgacaa tgcctgtaaa ccactgatcg aaaccagaaa gccacgacag
     2701 atggaacttt acgatccagc ccaaaatgaa aaacaggaca agaaagaagc taccagccac
     2761 ctgaaatgat gttttatatt tcatacaatt cctcctttga agcaatgact tattatagca
     2821 tttttggtcc agcgaaaaaa acggtaaaga gataaaacca atgtatgatt cctctttgaa
     2881 taaccaatat tcttataaaa aaaataactg taatcggaaa gacatttttt ggtaatgcaa
     2941 atgaaatgtt agggaaataa aatcagtgtt tttcgaaatc cttttaaaca agaacgtaga
     3001 cgtaggaaga acttgaaaat gaacagaagt tgttcattac ggtaaattac aatatgatta
     3061 caaaaaacaa caaagctctt aaataacttt taataaatat taagagaagt tataattatt
     3121 aataatagat aaattgaagt tggaggatag aagatggaaa acattgcaag aaaagaacgg
     3181 agacgtttag aacagaccaa acgttttcga aaagcaaaac gaggggcagc aatcgtggga
     3241 actgcgatgg taggctgttc tgtcgctgcc ccattagtac agccggttcc tgttcaagcg
     3301 gatgaaacac ctgttcagtt cggcgcaaga atcaatacag cggcatttat cacagaaatt
     3361 gctacttatg ctcaaccaat cgctcaagcc aacgatctat atgcatcagt gatgatcgca
     3421 caagcagttg tagaaagcgg ttggggcagt agtgcgttat ctcaagcacc ttattataat
     3481 ctttttggga taaaaggcag ctatcaagga caaaccgtct acatggatac gcttgaattt
     3541 ttaaataatc aatgggtaaa taaaaaggag cctttccgac aatatccttc ttttgctgaa
     3601 tctttcaatg acaatgccta tgtacttaga aatacttcat ttggcaacgg ttattactat
     3661 gccggtactt ggaagagcaa cacgaaatcc tatacagatg cgacagcttg tttgacaggg
     3721 cgttatgcga ctgatcctgg ttacgcaggc aaattaaata atatcatcgc aacttacgga
     3781 ttgacccaat atgatacacc agctagcgga aacgcaggcg gtggagcgac tacaggtggc
     3841 aataatactg gaagtgcagg tagtactggc ggttcaagca attctggtaa tacaaactca
     3901 ggttcagcaa cttcgaccac ttatactgtc caatctggtg attctgtttg gggaatctca
     3961 aataaattcg gtatcacaat ggatcaattg atccaatgga acaacatcca aaacaatttc
     4021 atttatccag gacaaaaact gacaatcaaa ggtagccagg aaaatggctc ttcgacgaat
     4081 aattccggta acaataccaa ttcttcagga aatgctggta catcaaacgg aggacaaaca
     4141 actggtgcga aatacactgt tcaatctggt gattctgttt ggaagatctc aaatgatcac
     4201 ggaattacga tggctcaatt gattgaatgg aacaatatca agaacaattt cgtttatcca
     4261 ggacaacagc taatcgtatc aaatggcggt tcttctaatg ctggagcaaa tactggctca
     4321 aatactggga atacaagtgg ctctagttcg tccagctcaa gttcttctaa tacagcttca
     4381 ggaacgaaat atacagttaa agccggagac tctgtttgga gcgtctcaaa taaatacgga
     4441 attacgatgg ctcagctaat ccaatggaac aatatccaaa ataactttat ctacccagga
     4501 caacaactga ctgtttcaaa cagtggatca acaaacagca cgtcaggtaa tacaggttcg
     4561 tcaaccaata caaataacag cagttcagtt aatactggca gcagttcgtc tcaaggcact
     4621 tataccgtga aagcaggtga atctgtttgg agcgtggcaa ataaaaacgg catcacgatg
     4681 gatcagttaa tcgaatggaa taatatcaaa aacaacttca tttatccagg acagcaattg
     4741 atcgttaaag gtggaacttc ggcaaataca aatacaggtt caactacttc tgcagcgaaa
     4801 ccaaatacac cgaatacgtc tgctacgaca agtacatcat ccactggtaa tacgatgtat
     4861 accgtgaaag cgggcgagtc agtttggagc gtagcgaaca aacatcatat cacgatggat
     4921 cagttaatcg aatggaataa tatcaaaaat aatttcatct atccaggaca gcaagtgatt
     4981 gtgaagaaag gttcatctca atcaacaaac caacaatcag ttactggttc gaaaacctat
     5041 actgtgaaat ctggagaatc tgtttggagt gttgctgaca gtcatggaat tacaatggct
     5101 caactaatcg aatggaacaa tattaagaac aactttattt atccaggtca aacgttgatt
     5161 gtagctaaat aaaatagctg ttcgaagaaa taacgattga attccacaaa aatatttgtt
     5221 actataaggc tacttaaata tgacaacact tgaaaaggaa gtagtaaaaa gactgaagtt
     5281 tcagagagcg catggctggt gagaatgtgc acggatgctt ttgaactcgc ctttgagttg
     5341 cccttgctga atacccgagt aagcaagcgg cggtgacggc cgttacaacg ttcgaggcct
     5401 tttcactaag gtaaaattag gtggtaccgc gtagattacg tcctataaaa agagcaatct
     5461 ttttatagga tttttttatt tcttttgtga agtttgagaa aacaaagcaa aaggaaataa
     5521 aaataaacag attctgccgg ttttttcgtt atatttataa tagaaacaag tgttttcaat
     5581 agaacaggag gacagcaaat gagttacaat cataaagaaa ttgagaaaaa atggcaaaaa
     5641 tactgggcaa aaacgaatac tttcaacacc catgatgatc ctgaaaagcc aaaattttac
     5701 gcactggata tgtttcccta tccatccggt caagggctac atgtagggca tcctgaaggt
     5761 tatacggcaa cggatatcct ttcacgtgtg aaaagaagtc aaggatacaa cgtgctgcat
     5821 ccaatggggt gggatgcatt cggtctgcct gctgaacaat atgcgctaga tacaggaaac
     5881 gatccagctg agtttaccca aaaaaatatc gaaacattcc gacgccaaat caattcttta
     5941 ggatttagtt atgactggaa tcgcgaagtg aatacaactg atccggagta ttataaatgg
     6001 acacaatgga tctttacgaa gctttatgaa aaaggtctag cttatgaagc agaagtagcg
     6061 gtaaactggg tacctgaatt aggaacagtt atttcaaatg aagaagtgat cgatgggaaa
     6121 agtgaacgtg gtggctatga tgtagtcaga aaaccaatgc gccaatggat gctgaaaatc
     6181 actgcttatg ctgatcgctt attggatgat ctagaattag ttgattggcc agaaagcatt
     6241 aaagaaatgc aaagaaattg gatcggtcgt tcagtaggag caaatattga atttaaagtg
     6301 gctggtacgg ataaatccta taccgtattt acgacacgac cagatactct attcggtgca
     6361 acttactcgg ttcttgcacc tgaactagat cttgttagag aaattacgac ccctgaacaa
     6421 aaagctgctg tagaagctta tatcgaagag acagctaaaa aatcagatct aaagagaacg
     6481 gatcttgcaa aagaaaaaac aggagtattt actggtgctt atgcaatcaa tccagttaat
     6541 ggcaaggaaa tcccaatctg gatcgccgat tatgtattat cttcatacgg cacaggagcc
     6601 atcatggctg ttccagcaca tgatgaacgt gactttgaat tcgctcaaac tttcggacta
     6661 gaaattcttc cagttatcga aggtggagat gttgaaaaag ctgcttacac agaagatggt
     6721 acgcacatca actctgaatt tctagacggc atgaacaaac aagaagcaat cgataaaatg
     6781 aatgaatggc tagaagaaaa tggcgtaggg aaaaaagaag tcagctatcg cttacgtgac
     6841 tggctattct cccgtcaacg ttactggggt gaaccaatcc caatcatcca ttgggaggac
     6901 ggaacagtca cagctgtccc agaagaagag ctaccattac ggttgcctaa gacaaaaaac
     6961 atcaagccaa gcggtactgg agaatctcca ttagcaaata tcgaggagtg ggtcaatgtc
     7021 gttgatcctg taacaggtaa aaaaggccgt cgcgaaacga atacaatgcc acaatgggca
     7081 ggaagctcat ggtattacct gcgttatatc gaccctcata acaaaaaaga actagcagat
     7141 tatgaaaagt tgaagcgttg gctaccagtt gacatctaca ttggtggagc agaacatgcg
     7201 gtacttcatt tactatatgc acgattctgg cataaattct tatacgatat cggtgttgtt
     7261 cctacaaaag aaccattcca aaaactatac aatcaaggaa tgatcttagg cgaaaacaac
     7321 gaaaaaatgt caaaatctcg tggtaatgta gtcaatcctg atgatgtggt cgaaacttac
     7381 ggtgcagata cactgcgcat gtacgaaatg ttcatggggc cattagatgc ttcgattgct
     7441 tggagcgaaa atggcttaga aggaagccgt aaattcttgg atcgtgtatg gcgtttgatc
     7501 gttgatgaga acaataaaat gcgtgaccgt atcactacat tgaatgatgg caagcttgat
     7561 aaagtgtatc atcaaacagt gaaaaaagtg acagaagact atgaaaatct tcatttcaat
     7621 acagcaatct cccaattgat ggtctttatc aatgaagcct ataaagtgga cgctctgcct
     7681 tatgaatata tcgaaggatt tgttcaacta ctcgcaccga ttgctcctca catgggtgaa
     7741 gaactatggg caatccttgg aaatgatggt ggtatttctt acgcaccatg gccaacatac
     7801 gatgaagcag cacttgttga agacgaagta gaagttgttt tccaagtaaa cggtaaagtt
     7861 cgtgcgaaaa gcaatgttcc ccgagactta ggaaaagatg agctagaaaa agcagcatta
     7921 gccaatgaaa tagtgcaaga atatattgaa ggcaaaacag tcagaaaagt tattgcggta
     7981 ccaaacaagt tagtcaatat cgttgctaat taattggctc tttgtcaata aggactgatg
     8041 agttgtgcaa aatcaaatct gggccagaat gaacttcatt ctgtctcaga ttttttgtta
     8101 tttcaaattg attaattgat tgatcaaaaa ggttttgatt ttcatgttct caaacacgtt
     8161 caatgtcttt ttcttctgaa tggtcttgta agagatctct gtaatcatca aatttttgtc
     8221 tattaatctt agtatttttt gatgtataaa ctacctgaaa ttgagagtac ataccaaatt
     8281 cataaatttt ttattagtgg gactagtgat tgtatggatt ttgacgcata atgaatgaag
     8341 tatgagaaaa ggagagacaa atggatcaag aactatttat tatcgaagta ttatcagcta
     8401 aacaaaaaat tatcgagaaa gcgaaaaaaa gagcgaaaag aataatgttc aagcttttaa
     8461 gcttagtatt tttctctggt ttgctttttt tcggagctgt atcgttccta tatcgccata
     8521 tgagtgcagt agtccgttca gctgaaggga tgcaaaaatt aaataatttg tatcactttt
     8581 cgtggggagt tggcggaata acaattgttg tgcttattgt ttttcttcta cttatttggc
     8641 tccgttacca tcaattgtcg cgtcatttcg atcaatggct tagtcaaaga gcacaacagt
     8701 ttttacataa taaaccaact tctcaagatg atgactatct ttattttgag aagacttcga
     8761 cgagtcaagc ttttcggata caaaaaagtg attgccagtt attgctgaga tcacttgatg
     8821 atttacctat ctacttaggc gaaagcaaat caaaattcgg aatgaacaca ttccatattt
     8881 ttttactaga aaacgaaccc agatgggaaa aaagccagtc ttcgcctggt ggatacctga
     8941 caactaagat gagtacatta gtcactggtt ttttcctcat tcttttagct ggaacaatct
     9001 attatgggag atacactcag ccaaaaatgt cttctcatat aaatgctgct tctcacatga
     9061 caatgaactc aactaacgat acgcatatac aaaagacaaa tgaagggttg ttagctgatc
     9121 ctaagcaaaa ggtaaatttg acaacacaaa agataaatga tctcaaactt gatacagaga
     9181 cgcactctct ctatatgaca acagatagtg gtgctaattg ggtatttgtg ccgattgatt
     9241 cgcaatggtt gcgttttggc gaatacaccc tgacaacggg gctgattcct gaaggttatt
     9301 ggatggacaa cacatatgat atttccgccg atttctcatg gtttatctat tcttctgggg
     9361 atgatgtacg tctgctgact tcaagagata atggtaaaac atggcaaacg tctattatca
     9421 cccaatcagt tcagccgata cgttatcgaa aagcggtatt ttatggcaac gatggtctat
     9481 ttatctgtac atcagccagt gggatgtctg cagaaacttt gtacatttac actactatgg
     9541 atggcggaat cacttggata aaaagtggaa gtacaatgat caatcagcca gtacaaaatg
     9601 tcagcttcgt tacaacttct ttaggttttg tttcgacacg tgaaagtttg ttttatacaa
     9661 acaacggagg acgctcattc aaagaatcag ttctgtcgat tccggaaaac tatcagacag
     9721 gggggataga tctttttcaa tcaccaaatg aagttactca aataagcgcg aatacgttag
     9781 agacaaaatt ttatttgttg aaaaaaggac caatcgatgc agggaaaatg tttgcctgcc
     9841 tcttccgttc aactgataac ggggaaacat ggcaattcgt tcagcaacta tcgcaagtag
     9901 aacaaggaga ttaaagaaga gagattgtga gcctgacgtt cagcaccgag tcacaagaaa
     9961 caaattcaaa aaacagcttc tcatatttgt tgaatagtgt aactcgtgat tcggagttga
    10021 caagagcaac aagaagcgat tttgaagtat agcttctcgt attttacaag atcgtgtctt
    10081 attgccgata ggttgtctct tgaacaccgt ttattcgtaa aaagggattg tgacaagtct
    10141 tttgtcacta cttaccgaac gaaactgaag gagctatcca aaaagtatca ttagtattat
    10201 tctttgtgtt tctagtggca ccactagtac atttaaaaaa gctatcgatc atggactaat
    10261 catacatgat cgatagcttt ttagataatg tttgttacgc tatctgaaat tgactattat
    10321 aaagactggc ataaagcgtt ggtgattgga gtagttcaga atgtgttcct ttttcgacga
    10381 tatcgccatt cttcattaca aggatcatgt ctgcattttc aatcgttgac aaacggtgtg
    10441 caatcacaaa acttgtccta tcttttgtca cagcttccat tgcttgctga atcaatgctt
    10501 ctgttcgtgt atctacgcta gaagttgctt catctaaaat aacgacagga ggattcgcta
    10561 gaatgactcg agcaattgtc aataattgtt gctgtccttg agataacgtg ccgttttcgc
    10621 tagaaatgat cgtatcatat ccgtctggca gtgttcgaat aaagtgatca cattgtgcga
    10681 tttcagccgc ttcgataatt tgttctcttg tggcatccat tttcccgtag gcgatattat
    10741 cagctaccgt tccttcaaac agccaggtat tttgtaaaac catcccaaaa gaacgacgta
    10801 gttctccacg tgaaagcttg gtaatatcaa gaccgtcgaa ttcgatcttt cctttattca
    10861 gttcataaaa acgcatcagc agattgacta aagtcgtttt tcctgcacca gttggaccaa
    10921 cgatcgctac cgtttgtttt ggctttactg aaaaatcgac ttgattcatc aatattttat
    10981 ctgatgtgta accaaactgt acatttttga aagctatttt tcctttcggt tgttctaaaa
    11041 gtcttgcatc tggaaggtct ggaatttcat ctgtttcatc taatatctca aatatcctat
    11101 cgattgctgc cattgcggat tggatcgagt tgatcacata agaagcggta gaaattggtt
    11161 cagaaatctg attgatgtac tgaagataag cttgtaagaa gccgatcgtc acaccacctg
    11221 atagaacaag catagcaccg aataccgcac ttatgatgaa ggcgagttga ttaatgaaac
    11281 gaatggccgg atagatagca cagttcataa attgagcacg tttaaaagcg ttgtattgct
    11341 ttttatttac ttcgtgtata gcagcttctg catgagcttg ctgattgaat gttttgacca
    11401 ctagattacc agctaagatt tcttccattc gattatttaa aacacccagt tcatactgat
    11461 tctgttcaga aatctgtttg tttttgttcg caatcttagt tgtaacaatt gaactgccaa
    11521 cgatcagcaa taagacgagc aaagtaagct tgctttcgat ataaaacagc atcagaccag
    11581 cagcagctat tgttacgaca gaagtaaaaa attgattgat acctgtcaat aacacttgag
    11641 aaagttgatt gagaccggta gttgtccgac taatgatgtc acctacttga tgattgtcaa
    11701 aaaacgacat cggtaatgtt ttgaattttt ttgtgatttc ttttcgcacc ctcaatgtga
    11761 tcttttcgct taacgctgcc attgtccgtt cctgaataaa tgaagtgatg ctgcttaaga
    11821 ctgaacagcc gatcagcaat aagacaggga acaacaatgc ttgtttgata tcactgaaag
    11881 aaagctgtcc aatacctgtt tttcttattt ctgataagag atcatcgatc ccgattccca
    11941 tgatcaaggg catggctacg actaataggt tcccgaataa actgcataga aacaatccgt
    12001 aaaaatattt atgttcaggt ttgatcattt tccaaaaacg tatcaaagca cgcgtgttca
    12061 acgttttttt cttttccatc gtatcccttc tttctatatt ccttgtgatt ttgcaaactc
    12121 ctgataagtt tggcaattag acagtagttc ttcatgagta ccttgtccaa cgatttttcc
    12181 ttcatctaaa acaatgatgt tatctgcttg ttggattgta ctgaggcgtt gagcaacaat
    12241 cacgagagtt ttctccgaca tgtgtttatg aagggctgct cttaatgctg catctgtttt
    12301 atagtctaaa gcggagaaac tatcatcgaa tacatagatc tctgctggtt tgatcaacgc
    12361 tcgagcaata catatccgct gtttctggcc ccctgaataa ttagaaccgc cttgagcaac
    12421 aaagctgtcc aatccgtcag gaagggtgtc cactagttct tctaattgag cgatcttgat
    12481 cgctttagac aactcttctg ttgaggcata ttcatttccc atctgcaagt tgcttaaaat
    12541 tgtcccgctg aataagaaag ccttctgagg gacataactg atgtgggagc ggatctgttc
    12601 ttgagtcatt tgagtaagag gaataccacc aagggttact tttcctatcg tagggtcact
    12661 aagtctcaag agaagtttcg ccaaactact ttttccagat ccggtcccgc caacgatcgc
    12721 tgttgttttt cctttaggta ttgtgaaatc aatatcttct agaactggat cagagatttc
    12781 agtatattta aatgtgacat gttcaaaagc agctgcattt gtctgatcaa aggttggttc
    12841 agctactgtt ttgatcgtct cttcctcaat ttcgatctct gcttgcagta tttcttctat
    12901 ccgtcgtaat gaggcaaacg atttagggat aatgaccaat accatagctg cgatcatcaa
    12961 gtaagcaagt gtcagcatag agtattcgac tacagcagtc acgacaccga tttgtaatgc
    13021 tccttctgct acaagatttc cgccaaacca caaaatagaa gcataaacga ttcccatgag
    13081 caaaaaagca attggagtga cccaagcaaa tattcggttc actttgatca tttgattagc
    13141 atagtcagca aagctcttat tcgttcgctt ttcttcatat gattgattat caaaggcacg
    13201 gatcatatta atcccagtaa agaattctct caatgtgatg gtgatccgat ccatttttgg
    13261 ctggatactc aaagataaag gtgcccctcg tttcatcagt cgataaacaa tccatacata
    13321 aaaaacaaca gagatcaatg taacccatgt tagtaataga gaataacgaa acatcatgag
    13381 aatggtgaaa acgcaaataa ccggtgctgg taagatcatt tggcaaaata aaacaatcat
    13441 ttgctggaca ttatcgacat cattcgtcat tcttgtcaaa agagatccag aactaaaacg
    13501 actgatatcc ttcattgaca gctgttggaa tttacggaaa tatttctccc gcgtttggaa
    13561 tccaaaccta gcggaagcca atgctgaaaa gtaactagag gcaactgcag cgattgttcc
    13621 tagaaacgct acaagcagca tttcaactcc aatttttttt ataactgagg cttcgccact
    13681 tgctatacct gtgtcgatca gctttgctac taattttggt acacctaatg taccggcgat
    13741 ttctaaacag atcatcacaa aggtaaggag agcgagtcct ttgtttttct gtaagaatgt
    13801 ttttaagata gacatattat tcctcctttt ttcctgatac ttttcgattc tataccttca
    13861 agtaacttga aggtcaatag aaaaaagaat aaactgaaaa agaggtgaga aaaaatgaaa
    13921 aaaatgtata cgattggcca agtatcggaa ctatttgatt tgccaaaatc aacgatccgc
    13981 tattgggatg aacaaggatt aatccgttca agtagacaag aagagaatga ttatcgattg
    14041 tttgatatcg atgatatttt tatgctttat gatatcgttt tttatagaaa attagatata
    14101 ccgatcaaac agatgaagaa tttatatgga aaaacattga cggagttata tgagacactt
    14161 gatgaaacag aaagaagaat ccataaagaa ctggtggtga tgaaacaaaa acaaaaagag
    14221 ataagggagc aaaaaaaaca gttgaaattg atgatcgata caaacgagga agaatttcct
    14281 gtagaagaga tcccttttga ctgtatgatc tcaacggagt ttgaagatat tgtggaaatc
    14341 aaaaaatttc tacctaacta ttcaagcttt gggatgatga gtatgccagc ttccagttca
    14401 cagacgatgt atggattttt tatcgaccct agtgaagtac atttatttac tcaagacgtg
    14461 atttgggaga aaaaagatac ggctgtttat cgtcgattct tattgaaatc cgagatgaac
    14521 catgcggaac gtaataatat tttagaaatc agagaaagaa tgtatgaaaa aggatggaaa
    14581 acaggagaag tgatcggcca gtatctattg acgaatacgg atgaaaacaa tatcagaact
    14641 gaatattatc atgcatggat agaaatgaaa aaataggaaa tatgtgttta agataactcg
    14701 aaaatgatgg ttgttttagt tataaagaaa aattttctgg ttcgattacg ggtttaatgt
    14761 gggggattat tagtcgtgga tagatagaat tttagttttt tagaggaaat at
//
LOCUS       DADLIO010000064        14805 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.067, whole genome shotgun sequence.
ACCESSION   DADLIO010000064 DADLIO010000000
VERSION     DADLIO010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14805
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.067"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            <1..135
                     /locus_tag="JOX41_002180"
     CDS             <1..135
                     /locus_tag="JOX41_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAY6449897.1"
                     /translation="FNQVNQGFISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA
                     "
     gene            complement(313..2310)
                     /gene="tkt"
                     /locus_tag="JOX41_002181"
     CDS             complement(313..2310)
                     /gene="tkt"
                     /locus_tag="JOX41_002181"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HAY6449898.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2412..2663)
                     /locus_tag="JOX41_002182"
     CDS             complement(2412..2663)
                     /locus_tag="JOX41_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HAY6449899.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2810..3433
                     /gene="lexA"
                     /locus_tag="JOX41_002183"
     CDS             2810..3433
                     /gene="lexA"
                     /locus_tag="JOX41_002183"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HAY6449900.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3613..3831
                     /locus_tag="JOX41_002184"
     CDS             3613..3831
                     /locus_tag="JOX41_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449901.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(4120..4632)
                     /locus_tag="JOX41_002185"
     CDS             complement(4120..4632)
                     /locus_tag="JOX41_002185"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HAY6449902.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4646..6943)
                     /gene="recJ"
                     /locus_tag="JOX41_002186"
     CDS             complement(4646..6943)
                     /gene="recJ"
                     /locus_tag="JOX41_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HAY6449903.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(7085..7519)
                     /locus_tag="JOX41_002187"
     CDS             complement(7085..7519)
                     /locus_tag="JOX41_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HAY6449904.1"
                     /translation="MKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPLILV
                     IIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQREFRN
                     ERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7529..8317)
                     /locus_tag="JOX41_002188"
     CDS             complement(7529..8317)
                     /locus_tag="JOX41_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAY6449905.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8314..9255)
                     /locus_tag="JOX41_002189"
     CDS             complement(8314..9255)
                     /locus_tag="JOX41_002189"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HAY6449906.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9432..10019)
                     /locus_tag="JOX41_002190"
     CDS             complement(9432..10019)
                     /locus_tag="JOX41_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HAY6449907.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10240..11553)
                     /gene="obgE"
                     /locus_tag="JOX41_002191"
     CDS             complement(10240..11553)
                     /gene="obgE"
                     /locus_tag="JOX41_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HAY6449908.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11841..12851
                     /gene="gap"
                     /locus_tag="JOX41_002192"
     CDS             11841..12851
                     /gene="gap"
                     /locus_tag="JOX41_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAY6449909.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12936..13871)
                     /locus_tag="JOX41_002193"
     CDS             complement(12936..13871)
                     /locus_tag="JOX41_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAY6449910.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
     gene            14057..>14805
                     /locus_tag="JOX41_002194"
     CDS             14057..>14805
                     /locus_tag="JOX41_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HAY6449911.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERSVS
                     CGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPDNYPDFNSEF
                     GHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFK
                     SITFDCGKEFSNWKAISNQHDIDIYFADPGTP"
BASE COUNT         4169 a         3277 c         2607 g         4752 t
ORIGIN      
        1 ttcaaccaag tcaatcaagg attcatctca tccgttgcgt ccaaaagaaa ccatatccct
       61 agaaaatcac taaattacca aacaccatta gaagtttttt tgagttacgt aaatggaaag
      121 ttttgtctcg cttaatttga caaataatat tctcaagaaa cacaaactaa tccgaagaat
      181 tctttgtttt gtcatttaaa tgtaacatag ccgaaaacga aaagtaatat tgatttattc
      241 ttctaacaca taaagaacag ctgtctccaa cttgcagaca gctgttctta tcagtcaaac
      301 aattgcttgg atctatgata gttgattgta cgtattcacg acattttcta ctgtaaatcc
      361 aaattcttct aaaattttag tgccaggggc agatgcaccg aaatgatcga ttgtaatcgt
      421 tgcgccctct gttcctacgt agcgttccca tccaaatgat gcagcagctt cgatagccac
      481 acgtttcttc actgatttag gaagtacact ttctttatat tcagaagatt gtttttcaaa
      541 gaggtcaaag cttggcatag aaacaacaga aacatctttg cctttttcag ccaattcttt
      601 ttgagctttc acagccaaat caacttcaga acctgttgca atcaaaatac cttctggtgt
      661 ttctccttgt gatggagaaa gaacatacgc gccttttttc accatttcat ctgctacttc
      721 ttttgtagaa ggcaatactg gaaggttttg acgactcaat acaaggatag taggcgcatc
      781 tgttgtctcc atcgctactt tccaagcagc acgtgtttca tttccgtctg ccggacgaat
      841 cacttgaaca ccaggcatgc agcgaacaga tgctagttgt tcaatcggtt cgtgcgttgg
      901 tccgtcttct ccgacagcaa ccgagtcatg tgttaagacg taaacaacag gagtatgttg
      961 gattgctgct aaacgaactg ctggtcttag ataatcgaca aagacaaaga atgttccacc
     1021 gtagatacga gttccgccat gaagttggat accattcata gccgaagcca ttgcaaattc
     1081 gcggacaccg aaccagatgt tgcgtccttc ataatgttca ggagtgaaat ctttatctgc
     1141 agccaccatt gtattattgg aacctgacaa gtccgctgaa ccaccccaga agcttggtat
     1201 agctttcgat aattcttgga tgacttcttt acttgaaaca cggcttgctt gactgcttcc
     1261 aacttcataa gttggcaatt ctgcatccca gttttctggt agtttgccat caaaagcatc
     1321 ttcaaattgt tgtgctaatt caggataagc ttttttataa ttggcaaaca tttcattcca
     1381 tgcatcttca gctttttgtc cttcttctat catcgtttga tggaagcggg cagctacttc
     1441 ttctggaaca gtgaaatctg gatactccca accataaact tctttagcca tcttgatgcc
     1501 atcttcacca agaggagcac catgaacagc agatgttcct tctttaggag caccatagcc
     1561 gatgactgtt tttacttcga tcaatgttgg tttgtctgtt tcagcttttg cttcttcaat
     1621 cgctttagag attgcttcta ggtcatttcc gtctttcact aagatatgtt gccagccata
     1681 tgcttcatag cgagcaccaa cgttttctgt gaaagctttt gaagttggac cgtctagtga
     1741 aatatcgttt gaatcgtata aaacgatcaa tttccctagt ttcatatgac ctgccatcga
     1801 acttgcttct tgagataccc cttccatcaa gtctccgtca ccgcatattg catacgtata
     1861 gtgatccatc acattaaagt tttctttgtt atacgttgct gcaaggtgcg cttctgccat
     1921 tgccataccg acagccattg caatcccttg tcctaatggc cctgtagtgg cttctacacc
     1981 atctgtatga tgtacttcag gatgtcctgg tgttttagaa tcccattgac ggaattgttt
     2041 caaatcatcg attgtcactt gatagccagc taaatgaagc aagctataca acattgctga
     2101 cccatgtcct gccgaaagaa cgaaacggtc gcggtcagcc cagttttttg atgtcgttgg
     2161 atttactttc aggtgttttg tccataacgc atatgccata ggtgctgcgc ccatcggcaa
     2221 tccaggatgt cctgagtttg ctttttggac tgcttcaata cttaatgtac gaattgtgtt
     2281 aacgccaagt tggtcaattt tgtcaaacaa aataacccct cctattaatt taggtttttt
     2341 ttacctttat ttcttacact ttcattctat aagatgtcac acgaaaaagc aatctttttc
     2401 agtatttttt actaaaagtt gtcatttcgg ttgtgtaagc cttttttctt ttggatttct
     2461 tttaattttt ccggggtcac gtcattgccc tcaggatcga cgactttcat tccttcgata
     2521 tgatgacgca taccggaacg aaaagcttcc aaatactctt tgcgcaagtt gatttgttct
     2581 tgttcttcgg cttttgagag accattttcc ttctttttac gtgcaagttc attgatccgc
     2641 tctatttttt caggtgacag catgctcagc cctcctttta ctctccttca tattatataa
     2701 aaactgaaaa aaaaacaact agataaacta aataaaatac gaacattcgt ttgatttagc
     2761 gctttttata tggtactatt tatttatcaa gtgaaagaag gtgtaccttg tggcccgaca
     2821 aactgaatca agacaaatcg aagtcttacg atatatccat gaacaagtaa cccaaaaagg
     2881 atacccgccg actgtccgtg aaatcgggga agctgttcag ctttcttcta cttctactgt
     2941 tcacggtcat cttgcacggc ttgaaaaaaa agggtttatc caaagagatc cgacgaaacc
     3001 tcgtgcaatc gagttgacaa aacaaggttt agaaaagatt gggattcgtc caacaactat
     3061 tccagtactt ggcgtcgtaa cagctggaga acccatttta gcagtagagg atgcttcaga
     3121 cttctttcca atccctccta atctttcttc cgaagaaggc agtctcttta tgctgacaat
     3181 tcgtggagat agtatgatca atgctgggat attggatggt gacaacgtga tcgttcggaa
     3241 gcaagaaact gctcaaaatg gcgatattgt cattgcaatg actgccgagg acgaagcgac
     3301 ttgcaaacga ttctataaag aaaaaaactt tttccgtctg cagcctgaaa acgacttgct
     3361 cgaaccaatc atcttagatc aagtatctat attaggacga gtagtaggac tttatcgtag
     3421 tcatatctat taattgctac taattaaaag aaaacttttt aaaaagagtt tgagacgttg
     3481 gtctcaaact cttttttcgc ccgggttctt cttctttcaa atttttatca cttccctctt
     3541 tacaaaccga acaaatattc gtatactaaa tatacgaaca attgttcgca taaattaaag
     3601 aggtgagaat tcatgaaatc aatgagacgt cttggcttag tattaactgt tttgttttta
     3661 ggtattatta ttggtaattt cggcatacgt ccagctttac ttgtgtttgt tccgttattt
     3721 actttgtggt tcatgttgtg ggatgaaaag aagtaccgtc aatctgagcg gcgcagaatt
     3781 catgaagatc atttctatca tgagccctac tacagatcca ggcaatcata ataaggattg
     3841 actgctaatt attcaaaaga caagaagtta aacttttacg ggggtgtgac aaaaatcggt
     3901 cacatccttt ttttcgaata aacggtgttc taaagccagt ttttcggtat taagtcaaat
     3961 tgcggaaaaa gtgatttttt aaacttctac tggtctttgc ttgtttccat ttataaaaaa
     4021 atagcgaccc tcaaaagtca gatagagaat ctgacttttg agggtcgctt taaaatcgct
     4081 tctttaagaa taacatcaag aatagcttct tttttctgct taatattcca ttaatgtaat
     4141 gatgtcatat cctttgattt tgtcgcgtcc atggagatcc atcaattcga tcaaaaatgc
     4201 gcagcctacg actacaccgc ctaattgttc gatcagttcg atcgtcgctt tgattgttcc
     4261 tccagtagct agcaaatcgt cacaaatcag cacacgttga cctggtttaa tggcatcctt
     4321 atgcaatgtc aatgtatctg ttccatattc taatccataa gtcacttcga tggtttctcg
     4381 aggtaacttc ccttttttgc ggactggggc aaaaccgact cctaactcat aagcaacagg
     4441 acatcctacg atgaatccac gggcttctgg cccaactacc atatcaattc gtttttcttt
     4501 tgcataattt acgatttgtt tagtagcttc ccgataagcg tcaccatctg ccatcagtgg
     4561 ggaaatatct cgaaacacaa ttccttttga cggatagtcg ggaatactgg caatataatc
     4621 ttttaaatcc actctttgtt tcctcctagg ttgttaacca tttctttatg gtaggaatat
     4681 cgctcaaaag caaaaattcc tcaactttga ttttattgag ccgtcgctgg tataatctgc
     4741 tctcagtcaa aggatgactt tctgggctag cgactttttg taaaacaccg ttctctattg
     4801 taacaaattt caattcaaaa aacacctgta tcataaaaat taataatttt tcagggatac
     4861 gcaaatattg agctattgct tttattttat gacgtatatc aattcgttct tgagaatgga
     4921 tcaatttaaa caattttgcg tactgttctc ttgtgcctac cccattcaaa taggcctcat
     4981 caggtgaaat ccccatcaga taaacacgat tgaatgaata agaccgaaaa acttctttca
     5041 gatccgctaa atcatctgga caatccataa caactagaga gtttggtttt cttttttcaa
     5101 ttattgcctt tacagaatct agtccttcga aaacaatcgc agcttcctgg ataatctcag
     5161 gcacgaattt caacgtcgaa gaatcaaatg ctaaataaag gctaccttcc gacgttcggc
     5221 tctgttcacg gaaacgtttt gcccgccaat caaatacttg cagaccaccc acagaaaaat
     5281 cagataccat cagctgcggt ttcttacgcc cgttccattc attgatcgaa agctttccta
     5341 ccacatctac ctgattattc agcagttctt cttcttgagt accaaaacca aaagcgaccg
     5401 catcaagctg actcgatgca tcggaaagga caaatttcag atgctgttgg tttgctccga
     5461 ttcttttgat attttctgct tggacttgtc gaaataaaaa ctgaggcaaa ggattatccg
     5521 taccaaatgg cgccaatagt ttcagctcat caattcgctc tactgttact tcatttggca
     5581 gcaatacttc atcaattctc aactcaggcc ctctcatcaa gtcaatttga tgatcgacta
     5641 tatattggtt catcttctcc tgtagtatag tgacattttc acttggcatc gttaaaccga
     5701 ctgctgcatg atgtcctccg aagtaagtaa ataaatctcg catctggtca agcatttcaa
     5761 aaagattcaa ggcttcaata ctacgtccag atcctttagc tgatccatct tcttttaaag
     5821 taaggacaag cgttggttta cccgtttcat tcattatttt cccagcaaca atgcccaaaa
     5881 cgccttcatg ccatcctcgg tttaccaata gatggatatg attctcctta ttgaccatcg
     5941 ctaatgcttc ttgtgttatc tgctctacga ttgcttttct ttcttcattg atctcattca
     6001 atttttttgc ttgaacggat gcttcctctt catcaaacgt cgcaagtaac gagacggcag
     6061 gacgtggatc gcccatccga ccgattgcat ttagtctggg agcaatcgaa aaaccgatcg
     6121 ttgtttcgtc tgcgtccctc atttttacgc cgctttcttc aaatagcgcc tgaagtccta
     6181 tccgttctga atgatgaatg gcatcgattc ctaatgaaac aaggattcga ttctcatcag
     6241 tcaatgaaac taaatcggcg atcgttccta tcgctactaa atccaaaaat tctgcaggcg
     6301 gttcttccaa taatgcagaa gctactttga atgctactcc gactcctgcc aaatctggaa
     6361 atggatagtg ccccgctgga tgacgagggt gaacaatcgc ataagcgtct ggtaaattct
     6421 caggtagttc gtgatgatct gtaatgatca cgtctacacc agcttgctga gcgtatgcta
     6481 ccgcatcatt tcctgctacc ccgttatcaa cagtgatgat caactggatt ccttcttcga
     6541 tcttttcttg gtataccgat tggtttggtc catacccatg ctcaaatcga tttggcagga
     6601 atacttctac ttctgcacca agtaattcca gtgtttcttt cattaccgtt gcactggtga
     6661 tcccatctgc gtcataatca ccgtaaacga ggattttttc tccactgatt acagcttctt
     6721 ggattcggct gattgcttta tccatatcgt gtatcagata cggatcatgt aattcttgtt
     6781 cctttggatg taaaaatcgg ttgatatcct tttcctcatg gtaacctctt tgccacagta
     6841 acttaccgac aaatggagat aatttcagtt cacggatcat ttggagaaag gattcagaag
     6901 gctctgtctc gcttaacttc caatcaaaat ttgcttgtct cactttctca ctcctaactt
     6961 agttattata gcaaaggaaa tcagcaaaaa aaagcagaaa gaaagaataa aaacagatca
     7021 gatccgctag acagatgttc agcaggacct gatcttttgt acgaccattt atgaaatatc
     7081 cctattagtc aaaataattg aagctttgtt tgggcgattg agttttttgt tcttccggcg
     7141 ctttcaattg actgatttgt gcggttttcg cttgtaactc cgcctgataa gcagcttcca
     7201 actccgcacg ttcgtttcta aactcgcgtt gctgttcttc ttttgcttct tcaattttct
     7261 tttgaagttc tgtttgatat tctgacattt cctgagtcag ctgtttgatt tgcttttttt
     7321 gctgccatag tgttgccgaa gcagtcaaaa atacaatcag tgcaccaatc agcgcagaac
     7381 cgatgatcac taagatcaat ggcgcagaaa aggaagtgaa gccaaaactt acaggaacat
     7441 ttttattgtt caatacagca aaaagaacaa taatcaaaac taaaacaaat ccaagaatca
     7501 cattgctttg ctttttcaat tccttcacct actttttgtt aaaaattccg ctggctaaat
     7561 aatcaccaat cgttggaaac agcgtataaa attttgatgc aacttctaaa ataaacggtt
     7621 gattgatttc ccgttttgga tgtctcatat tgcggacgat catttttgcc aacttggcag
     7681 gttctaaaac gatttgtccg actttttcca aatagcttcc gcttggatca gccttatcga
     7741 agaaatttgt ctcgattgga cctggattca ctgtcgtaac agctacgcca agtggtttca
     7801 attctaatcg caaagcgttg gagaagccaa ggactgcaaa tttcgtggca gaataaaccg
     7861 ttgattttgc agttgccatt tttccagcca tagaggcgat attaatgata tgaccttgtc
     7921 ttctttctgc catatcgatc gcaaattttt gtgtcaaaac catcattcct aagatgttga
     7981 cttcaaacat atcgtatgct tttccaaggt cgaatgtaag gaagtcttcg aaaatcccaa
     8041 aacccgcatt gtttaccaga atatcgacgc gcccgacttc ttccatcacc ttttcatata
     8101 attcgtccac gctttcagga ttgctgacgt ctaccttgaa agcataagcc tctttgccgc
     8161 tcaagcgtct gcactcgtct ctgacacctt ctacaaatgc cattcttcgt gcgcaactta
     8221 taacgattgc tccttgcttt gctgcttcat aacagatttg tgcgcccaga ccgcctgaac
     8281 tacctgttac taaaacaact ttatcttcta aattcatgcc tcttcctcct cgcgaaatgg
     8341 aatctcaatg ctatcaaaat ctttcataat cgtcgtgttt tcaaacactt cttgtgcttc
     8401 tttttcaagc tctaaagctg cttttcctaa atatctcgca ctgatatgag taagtagcag
     8461 ccgttttgcc tgcgcttctt ttgcaacttc agcagcttga tgagtcgtgg aatggaaata
     8521 gttgtgcgcc attcttgctt catctttatt aaatgtgctt tcatgtacca gaatatcgct
     8581 attttccgca agcacaacgg aattatgtgt ttttctcgta tcgcctaaaa tagtcacgat
     8641 tcgtcctttt ttatctggac ctacgaaatc ttttccattg atcgtccgcc catcttctag
     8701 ttggatcgtt tcaccttgct tcagtttgcc gtacagtggt ccagctggaa tacctaattc
     8761 ttttagacga tccacctgca attctccttt atgatcatgt tcaaccacac gataaccaaa
     8821 actgtcgatc ccatgattta gtttttttgt ataaacagaa aattgctgat cagtaaaaat
     8881 cggggctgtt tcatttagct caatgaattt cagcggataa cttaaacgcg tttgcgaaat
     8941 acctaaagag acttttatgt attcctctat cccttttggc ccgtaaatct ctaatggcgt
     9001 atccccacct tgaaatgacc ggctgctgat gagcccggga agtccaaaaa tatgatcgcc
     9061 gtgtaaatgt gtaatgaaaa ttttaccgat ttttctcgga cgaatagtcg ttcgcaaaat
     9121 ctgcatttgc gtgccttcgc cacagtcgaa caaccaaact tcattgcgct cgtctaaaag
     9181 tttcaatgct atacttgtca catttctatg ttttgcagga acacctgcac ctgttcctaa
     9241 aaattgtaat tccataatct acctgacttt ctttaagttc ctctttaatt ttagggtaaa
     9301 aagaagggat aatcaaccgt aagtcgagaa tgggttcaaa ttaaaaataa cgttctaaag
     9361 cgatagcgtt ttctttgaaa attactataa aaacagcagc gaacccgttt gagatcctct
     9421 gctgtttttt attaatttga agatccagaa ctttcattgt cgttggaagt ttgcggatgt
     9481 ttgtccttcc aagtcttttg tgcagcttct ttcgcatgat tttcagcttc tttcgcatca
     9541 tgcacatctt tttcgacatc ttcataatcc aagcgagtaa tttctccgcc taattccatc
     9601 attaccaatt gattcagtgg gcgattgtcc tcttcatcag caatcaagat cagtcctgta
     9661 gctccttcac cgattttatt tcctacaaag tcgaacacgg tctgggcatc ttttatttct
     9721 ttggcatctt gtgtcgcacc gatcattcct ccggcaaacc atcctaataa aatccctagc
     9781 ggaccaccta atacaccaac caacattccg attaatccac ccgtagaaga tttgttatta
     9841 ccggtaaagt cgataaaatc ttctattttg aattgatgtg tcccattagg atcatggctg
     9901 acaactgcca tctgttctcc tttaatcgaa cgaacagcat gtaacttttt gatttctgaa
     9961 aatgcctgat atgcctggct ttctacttga aaatttaaaa tgattactcg tttgctcatt
    10021 aaaaacgccc ctttcatacc ttcttgttat ttattttacc tttaattgaa aaataagaaa
    10081 agaaaagcac tctttttttc caataaaata gggctgtgac aaaagtcgta tcacagctcc
    10141 tttttccgaa taaacggcgt tcttgaagct gatcacttct gtcacaacct cccttaaatc
    10201 tgaatctata ttttttggta tttgttttta tttgcttgcc tattcgacaa attcaaattc
    10261 aaactcaccg atacgtacaa ggtcgccatc tttcgcaccg cgtgcccgaa gagcttcatc
    10321 cacacccata ccacgtaatt gacgagcaaa acgcatcact gtttcatcat gatcgaaatt
    10381 cgtcatttgg aataattttt cgatcttctc accagataag atccacgttg catctgaatc
    10441 acgatcgatt tggaactcag gaccttctgg attgaatcca tagtgtacag tttcttcttc
    10501 cagttcttct tcgtacaatg ggaattctgg cgttacttct aacaaatctg ctgtagcatt
    10561 caataacgcg tccaatcctt gtcgagtcac tccagaaatt ggaaatactg ggatgtcatc
    10621 agcaaattca tcttcttttt ccttgttcag ctgttctttg aatttcacta gattttccgg
    10681 tgcatccggc atatccattt tgtttgccac gatgatttgc ggacgctcta gcaagcgtaa
    10741 gttataagta gataattctt tgttgatggc aagatagtct tcataaggat ctcgtccttc
    10801 catcccactc atatcgatca catgtaaaat tactcgtgtt ctttcgatat gacgaaggaa
    10861 ttgtgtaccc agcccaacac cttgcgaagc tccttcaatc aagcctggca agtctgctgc
    10921 ggcaaaactt ctgccatcac ttgtagtaac cattcctaga ttaggtacga gcgtcgtgaa
    10981 atgataagcg ccgatttttg gacgagcaga tgaaataacg gatagtaaag tcgatttccc
    11041 gacagatgga aaacctacaa gtccaacgtc tgccaatact ttcaattcta gttcgatttt
    11101 tcgctcttgt cctggttcac cgttttcagc aatttccggt gcaggattcc gaggagaggc
    11161 aaaacggata ttccctcgtc caccgcgtcc accttttgcc acaactagtg tttgaccatt
    11221 ttcaattaaa tctcctaaaa gagcaccagt ctccgcatct cggacagtgg ttccttgtgg
    11281 tactttaaca taggtatctt ctgaaccacg accgtgcatc cctttactca tcccattttc
    11341 acctggctgc gctttgaaat ggcgattgaa ccgaaaatcc atcaatgtac gtaacccttc
    11401 atcgacgatc aagatgacat cgccgccacg accaccgtct ccgccagccg gtccgccgtc
    11461 aggaacgtat ttttcgcgac gaaatgcaac cattccgtct ccgcccttgc cagctttcac
    11521 atcgatcgtt acttgatcta aaaacatgga cataattaag tcctcctatt attcatttat
    11581 ttatttgact gcctgaattt ccacaataaa caaaagtctt acttatttta tcggtgaaat
    11641 ctgattttgt ctatcatttc agcaaaaaga ttgtttacct tcttcttttt ttatcatttg
    11701 gtaaggtttc caaccttttt tctgctacca agtataattt tttgacaaaa tattctttgc
    11761 gtagcagaat aacagtgtat taattgtatt aattgaggat gccgtttcac agcaccccta
    11821 ataaaggagg aacttttgat atgacagtaa aagtaggtat taacggattt gggcgtattg
    11881 gccgtctggc tttccgccgc atcaaagaag tctcagatga tattgaagta gtagcaatca
    11941 acgacttaac aagtccaact atgttagcac aattattgca atttgactct actcatggta
    12001 cttatcctgg cacagttact gcaacagaag actcaatcgt agtggatggc gaagcaactc
    12061 gtgtttatgc agaacccgac gcaagcaaaa tcccttgggc aaaagaaaac ggtgtagata
    12121 tcgtactaga atgtactggt ttttatacat ctgaagaaaa agcaaaagcg catttagatg
    12181 ctggtgtcaa acgagtagtt atttctgccc cagctggtgc tatgaaaacc atcgtctata
    12241 acgtcaatga tgatacatta gatgaaaacg acaaaatcat ctcagcaggt tcatgtacaa
    12301 caaactgttt agcacctatg gcttatttct taaataatga atttgggatc gaagttggta
    12361 caatgacaac agttcatgcc tacacttcca cacaaatgct cttagatgga cctgtaaaag
    12421 gcggtaattt gcgtgctgct cgttcagctg ctgacaatac tatcccacat tctactggtg
    12481 ctgcgaaagc aatcggctta gttatccctg agctacaagg aaaattacaa ggacacgcac
    12541 aacgtgttcc agtcgttgat ggttcattaa ctgaattggt ttcagtattg aaaacaaaag
    12601 taactgctga tcaagtaaac gaagcaatca aaaaacacac agttgacaat ccttcattcg
    12661 ggtatgatga ccgtcaaatc gtttctagcg atgtcattgg aacaactcaa ggttcgatct
    12721 ttgacccaac gcaaacagaa gtaacaactg ctggtgattt ccaacttgtt aaaactgttg
    12781 catggtatga caatgagtat ggatttactt gccaaatgat tcgcttacta gaaaaattcg
    12841 ctaacttgta atttgataga tcaatcgata aaagaagcct ttgactggat ccagtcaaag
    12901 gcttctttct tttcatcccc tacttttaaa ctcgttcaat gaacatattg gcttaaaaat
    12961 tgttggacta cttgctgata tttttcagga tctgtcttgt atgcttccgc atgctcggct
    13021 ccttttacaa catacttttc ttttggtccc ttcgttgcac gatagacctt atctaacatt
    13081 tcaaatggta caaatgtatc ttcgtctcca tgtataaaga gcattgggcg ctggtttttc
    13141 ttcaattgtt ccactgcatt tgcttcaccg aaaaagtagc cagcacggac ttttgtcact
    13201 agactcgtta cttgcataag cggaaatgct ggaagactaa acatatcgtc tagctgataa
    13261 gcaagctcat catgaacgga agaataaccg caatcttcaa tgattgcttt cacattatct
    13321 ggtagttttt ctccgctagt catcataact gttgctgctc ccatgctgac accgtataga
    13381 acgatttctt gcgattttcc attgttttct agcactttgt ttatccactg tacatagtct
    13441 ttacgctctg gccatccaaa tccaatgtaa tccccttcgc tttttccatg tcctcttgca
    13501 tcaggaacaa ggacattgta acccatatca tgaaacatct ttgcgtaatt ggtcatcgtt
    13561 tcagcgtttc ccatatagcc atgagccaca agagctgttt tttcactttt cgtttcagca
    13621 ggaagataaa tcgctgataa tttcagaccg tcttttgaag tgatggtcca atcgcttcgg
    13681 ttttcttttg aactaaacca tttatgtgca tccgtttctt tggatgtctg tgttgtacca
    13741 ggtgtatctt cgtctaaaaa gtctttctca gaaggcacaa cagcataatt ataaaaataa
    13801 ttccctgcaa acactaacgc aacaatcaga gctaaagcga cgcctaaaag gattttcatc
    13861 caaagtttca taaatcatcc atctcatttc tcttttttca tataaccttg aattagtata
    13921 atcaaagaat ctctactatg caatgttcat ttttataacc cgcgaattgt aaaattaagt
    13981 tagaaaaata aaaaggcatt tatggtacac tcaaattgta tttccgacga aagaaaacaa
    14041 aggagtgtaa ccataaatga cctacaaaca tcttaccata gacgaactga caatgataga
    14101 atcatattat cttcaacata ataagccggt tgaaatcgct aaccgaatgg gacgtgctat
    14161 acaaactatt tataatgtag tcaataagtt caagcaaggc aagactgctc ttgattattg
    14221 gcaccagtat aaagaaaata agaaaaaatg tggtagaaaa gtcattcaat tacctgctca
    14281 tgaagtagat tacattaaag agaaagtcac tcttggttgg acgcctgacg tcattatcgg
    14341 gcgaaaagaa aggtctgttt catgcggtat gagaacactt tatcgtttat tttctaaagg
    14401 aatatttgat attgacacac taccgatgaa aggtaaaaga aaacccaatg gccatcagga
    14461 aaaacgggga aaacaacagt atcagcgctc aatccatgat cgacctgata attatcctga
    14521 tttcaattct gagtttggtc accttgaagg tgatacgatc gttggcattc atcataaaag
    14581 tgccgtcatt actttagttg aaagattatc taaagtcatt atcacgatta aacccaacgg
    14641 ccgtaaggca ttagatattg aaactgccct taatcaatgg ttttctcgct tccctaaaaa
    14701 cttctttaaa tctattacgt ttgactgtgg aaaagaattt tctaactgga aagccattag
    14761 taaccaacat gatattgata tatattttgc ggaccctgga acacc
//
LOCUS       DADLIO010000065        14625 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.068, whole genome shotgun sequence.
ACCESSION   DADLIO010000065 DADLIO010000000
VERSION     DADLIO010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.068"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            4..816
                     /locus_tag="JOX41_002195"
     CDS             4..816
                     /locus_tag="JOX41_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HAY6449912.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            813..1613
                     /locus_tag="JOX41_002196"
     CDS             813..1613
                     /locus_tag="JOX41_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HAY6449913.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            1774..3042
                     /gene="rseP"
                     /locus_tag="JOX41_002197"
     CDS             1774..3042
                     /gene="rseP"
                     /locus_tag="JOX41_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HAY6449914.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            3110..4819
                     /locus_tag="JOX41_002198"
     CDS             3110..4819
                     /locus_tag="JOX41_002198"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HAY6449915.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            5031..9389
                     /locus_tag="JOX41_002199"
     CDS             5031..9389
                     /locus_tag="JOX41_002199"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HAY6449916.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            9534..10007
                     /gene="rimP"
                     /locus_tag="JOX41_002200"
     CDS             9534..10007
                     /gene="rimP"
                     /locus_tag="JOX41_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HAY6449917.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            10030..11205
                     /gene="nusA"
                     /locus_tag="JOX41_002201"
     CDS             10030..11205
                     /gene="nusA"
                     /locus_tag="JOX41_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HAY6449918.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            11227..11520
                     /locus_tag="JOX41_002202"
     CDS             11227..11520
                     /locus_tag="JOX41_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HAY6449919.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            11517..11828
                     /locus_tag="JOX41_002203"
     CDS             11517..11828
                     /locus_tag="JOX41_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HAY6449920.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            11841..14147
                     /gene="infB"
                     /locus_tag="JOX41_002204"
     CDS             11841..14147
                     /gene="infB"
                     /locus_tag="JOX41_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HAY6449921.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLQEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            14174..14521
                     /gene="rbfA"
                     /locus_tag="JOX41_002205"
     CDS             14174..14521
                     /gene="rbfA"
                     /locus_tag="JOX41_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HAY6449922.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
BASE COUNT         4982 a         2599 c         3255 g         3789 t
ORIGIN      
        1 agaatgttac gtttttttcc gcaaaaaaac aaatatattc aagaaaaaag cgaatttcaa
       61 tttaataccg atggaccaat tcctcagcac attgccatca tcatggacgg caatggtcgt
      121 tgggcgcaaa accgtcgttt gccacgagtt gctggccata aagaaggcat ggaaacagta
      181 aagaaagtca caaaaaaagc atcaaggctt ggagtgaaag tgttgacgct ttatgccttt
      241 tcgactgaaa actggaagcg accaaaagat gaagtaagtt ttctcatgca actacctgtc
      301 gacttctttg atacgttcgt accagaattg attaaagaaa atgtcaaagt tcatgtcatg
      361 ggttatgaaa acgtattgcc agaacatacg caagatgctg taagacgtgc aattgagcaa
      421 acaaaaaaca atactggaat ggtattgaat tttgctttga attatggaag tagagcagag
      481 atcgtgactg ctgtccaaga aattgccgaa gaagtagcaa aaggagaaat acacgcagaa
      541 gaaatcgatg atgaattgat tgctaagcat ttaatgacag gtttcttgcc taaagagtta
      601 caagatcctg agctgatgat ccgtacaagt ggagaagagc gaattagtaa ttttctgtta
      661 tggcagatcg catatagtga gctgtatttt acaaaagcgc tttggcctga ttttgatggt
      721 gcgcatcttg aagaagcaat cgcctcttat caaaatcgag accgtcgatt cggcggtgta
      781 aaaaaaacag aagatgagaa aggggatcag tcatgaaaca acgtgtgatc acagcagctg
      841 tggcgctagt cttgtttatt ccgattatat ggatcggagg catagcggtt gagcttacag
      901 cagcaatctt agcggtagta ggagtttacg agctgttccg gatgaaagga ttgacactct
      961 taagttttga aggagtttta tccgccgttg gtgcagtgtt acttgttttg ccaaaagaaa
     1021 gatggttttt ctttcttcca gagaatgtaa gtacatttat gttattttat cttatagtta
     1081 tgattctttt aggaacatca gttatttcta aaaatacgta tacgattgat gaagcaggtt
     1141 ttcctgtgct tgtcagcttg tatgtgggaa taggtttcca gaattttgtc aatgcacgaa
     1201 cagaaagctt ggctgttttg atatttggtc tatttattgt ttgggcaact gatatcggag
     1261 catatatggt tggtcgacgt tatggtcagc ataagttaag tcctgatatt tcgcccaaca
     1321 aaacgattga aggtgcgctc ggtggtatcg gtagtgctgt tgtagtcgca tttctttatt
     1381 tattgctata cccagcaaaa gaactattca atcatggtat gtttgtcatg cttctgatga
     1441 cgattatttt ttcagcagtc ggacaatttg gtgatttggt cgaatctgca atcaaacgtc
     1501 attatgatgt gaaagactcg ggaaatatct taccaggcca tggtggaatc ttagaccgtt
     1561 tcgacagttt gctgtttgta tttcctatca tgcatttatt tggcattatt tagtaagtat
     1621 acctgcgttt ctttgtgaat ttcataaaag acgcaggttt ttatttttca ttatattgat
     1681 actattggtg tctttggtat actatggtaa aattatagtg ttttatcgtt gttttataaa
     1741 aaacacaaaa aacaagtaaa ggagaaaaaa gctatgaaaa cgattctgac atttatcatc
     1801 gtttttggta tattagtgat tgttcatgag tttggtcatt tcttctttgc gaaacgatca
     1861 ggaatcctcg tccgcgaatt tgctatcggt atgggtccga aaatttatgg gcatcaagca
     1921 aaagacggga caacatatac gcttcgccta ttacctattg gcggttatgt tcgaatggca
     1981 ggcaatgggg atgatgaaac agaaatggca ccaggaatgc ctctttctct tttactaaat
     2041 tctgacggca tcgtagagaa gataaattta agtaagaaaa tccaattgac aaatgctatc
     2101 ccgatggaat tgagccgtta tgatttagaa gatgagctga ctatcactgg ttatgtgaat
     2161 ggagacgaaa cagaagtagt aacctaccct gttgatcacg atgcgacgat tattgaaaac
     2221 gacggaacag aaatcagaat tgcgccaaaa gacgtacagt tccaatcggc taaattgtgg
     2281 cagcgtatgc tgaccaactt tgctggaccc atgaataact ttattttggc aatcgtgtta
     2341 ttcatcattc tggcatttat gcaaggtggt gttcaagtga cgaacactaa tcgcgtagga
     2401 gagatcatgc ctaatggagc tgcggcagaa gcaggcttaa aagaaaatga tgaggtagtc
     2461 agtgtggacg gaaaagaaat ccattcatgg aatgatctga caacagtcat tacgaaaaat
     2521 ccaggtaaaa cattagactt taagatcgaa cgagaaggtc aggtgcaatc tgtcgacgtg
     2581 acaccgaaat ctgtagagtc aaatggcgaa aaagttggcc aacttggtat aaaagcccca
     2641 atgaatacag gttttatgga taagatcatt ggagggacgc gtcaagcttt cagcggttca
     2701 ttggaaattt tcaaagcctt aggatcacta tttacaggtt tcagtttaga taaattaggc
     2761 ggacctgtca tgatgtacca attgtcttca gaagcagcaa atcaaggtgt aacaactgtt
     2821 attagtttga tggcgcttct ttcaatgaat ctcggaatcg tcaatctgct tccgattcct
     2881 gccttagatg gcgggaaatt agtcttgaat atttttgaag ggattcgcgg gaaaccatta
     2941 agtcaagaaa aagaaggaat attgacatta gctggctttg gatttttaat gttgttgatg
     3001 gtgctagtta catggaacga tattcaacga ttctttttct agaaaaagtt gacaaatagg
     3061 gtataataac aaacgataac tattttgagg aaataaagga gtatatagaa tgagacaatc
     3121 aaaaatgttg attccaacat tacgcgaagt tccaaatgat gcagaagtat taagccatca
     3181 aatcttgcta agagctggat atatccgcca agtatcagcg ggtatttatt catatctgcc
     3241 attagcaaat cgtgtattgg aaaaactgaa acgcattatg cgggaagaat ttgaaaaaat
     3301 cggagcggta gaaatgctga tgcctgccat cttgccagca gaactttggg aagaatccgg
     3361 gcgttacgaa acatatggac caaacttgta tcgtttcaaa gaccgcaatg atcgaaaaat
     3421 gatccttgga ccaactcacg aagaaacttt tactgatttg atgcgtaatg aaatcaattc
     3481 atataagaaa ttacctttaa atctttatca aatccaacct aaatatcgtg acgaaaaacg
     3541 acctcgcttc ggtttgcttc gcggaagaga gtttatcatg aaagatgcat attctttcca
     3601 tgcaacggaa gaaagtttgg acgagacata taaagattac gaaaaagcct ataccgaagt
     3661 attcaagcgt tgtggcttag aatttcgctc gatcatcgga gacggcggcg caatgggcgg
     3721 gaaagactca aaggaattca tggcgatctc agaaatcggg gaggatacga tctgttattc
     3781 gactgaaagt gattatgctg caaacttgga gatggctaca agctactatg tatcaaaaaa
     3841 atcgcatgaa acacagcttg aattggagaa agtagctaca cctaacgtaa aatcaattga
     3901 cgaagtagca gatttctttt ctgttgaacc tcaaaaaatc atcaagtctg tattgttcat
     3961 tgcggatgaa caacctgtcc ttgttttggt acgtggagac catgaagtca atgacgtaaa
     4021 actgaaaaac tttttatctg ctgacttttt agaagaagca acagaagaag aagcacaaaa
     4081 atatctaggt gctgagtttg gttctgtcgg accagtcggt gtttcagatg acgtaaaagt
     4141 atatgcagac cgttatgtcc aagatttagc gaatgccatt actggagcga acgaaacagg
     4201 attccactat aaaaatgtga atccagaacg cgatttcact gtgctttctt atgaagatct
     4261 tcgttttgta caagaaggag atccttcacc agacaacaac ggtgttcttg cctttactcg
     4321 aggaatcgaa atcggacata tattcaaaat cggcactcgt tacagtgaat ctatgggagc
     4381 aactgtacta gacgaaaatg gacgagaaaa atttgtgatt atgggctgtt atggtatcgg
     4441 tgtaagtcgt ttattatcag caatcgtaga acaacattca gatgaacaag gaatcaattg
     4501 gccaaaagga attgcgccat ttgatctgca tatcgtccaa atgaatctaa aagacgaata
     4561 ccaaacaagc ctgacgaatg aactagaaga agcgatgaca aaagctggct atgaagtact
     4621 ggttgatgac agaaatgaac gcgcaggagt gaaattcgcg gattctgatt tgattggctg
     4681 tccaatcaga atcactgtcg gtaaaaaagc agtggatgga atcgtagaag tgaaaatcaa
     4741 gaaaactggc gaaatggttg aagtacgtaa agaagaattg gcgaatactt taccaatcct
     4801 cttgaaccaa ggcgaataat aagcgttaaa acacagaaaa taaaaatagc tgaatcagct
     4861 gtttttgaca atctgatgat tcgcttttaa aattggaact gcgatttgaa tcgcagttcc
     4921 aattttttaa tgtaaaactc agaaaaaacg agtatactaa aaggtactga aaaagaagag
     4981 gataagatgc gatcaattgc attgtttctc atcagaaagg gcgtatatct ttgtcagaaa
     5041 aacgagattt atttgaaaaa ctgttggaac aaatccaact agaggaagca gaaaaaaatc
     5101 atccactgct tactgctggt gaaatggata gtgtagtggt ccatcgtaaa tcgcgtttat
     5161 gggaatttac gctacatttt tccaaaattt tgcctattat gctatatcgg tcattgactc
     5221 agcatctgac tatcgctttt aaagatattg cacaagtcaa actgaatatc ttagcagatg
     5281 accagacatt cgatgaacag ctcttgcaag attactgggc ccaagctttg gaaaatcagc
     5341 aatgcgatac accactagca cagcaagtat tgaaaacgca ggtacctgtg ataaaagatc
     5401 gtaaagtcat cttgccaatc gacagtacag gagctatttc ttatttgaag caacaatact
     5461 tgccattagt agaagagttg ttcgtcagtt acggattccc aaaatttcgt atcgaaccag
     5521 aagtggatga gcagcaagcg gaacgagtat tgaaactttt tgaagaacgc aaacaagaac
     5581 aggcagaagc ctttatgaag caagcagctg aaagtctagt tgtccacgaa caaaagaaaa
     5641 aggaaagaaa agagcaatcg ccagctcttg aaggacccat ccacatccag ctaggacgaa
     5701 atattccagc cgatgaacca acgacaccaa tgatcagtat cgttgaagaa gaacgaagag
     5761 tcacacttga ggggtacgta ttcgacaaag aagtcagaga actacgttca aaacgcaaga
     5821 tcttgacttt gaaaatcaca gattatactt catcatttat cgtcaaaaaa ttctcgaacg
     5881 gcgaaaaaga tgaacaagta tttgatgcga tcagtgtcgg tagctggtta aaggtacgag
     5941 gaagtattca agaagatacg tttgtccgtg atttggtcat gaatgcgcaa gatatcatag
     6001 aagtcaaaca tacacctcgc aaagattatg ctcctgaagg ggaaaaacga gtagagcttc
     6061 atgttcatag caatatgagt acgatggatg caacaaacag catctctgat cttgtggcac
     6121 aagcagggaa atggggacac cgagctatcg ccattacaga ccacggtggt gcgcaagcct
     6181 ttccggaagc acatagtgct ggaaaaaaag caggtgtgaa aatcttatac ggcgtggaag
     6241 cgaatgtcgt agatgatggt gtcccaattg cttataatga tgcacatgaa gcattgagtg
     6301 aagccacata tgtcgtattt gacgtggaaa cgacaggatt gtctgcagta tatgacacga
     6361 tcatcgagct agccgcagtc aaaatgtata aaggaaatgt gatcgaaagc tttgatgaat
     6421 ttatcgatcc aggacatcct ttgtcacgaa caacggtaga tctgactggt atcacggatg
     6481 gaatggttcg aggatcaaag tcggaagaag aagtattgcg gatgttcctt gaattttcaa
     6541 aagatacaat tttggtagcc cacaacgcgg cttttgatat ggggttcttg aatactagct
     6601 acgcaaggta tggtattcct gaagcggcca atccagtcat tgatacgttg gaattagcta
     6661 gatatctgta tcctcaattc aaacgtttcg gattaggtgt gttatctaaa aaatttggtg
     6721 tcagcttgga acagcatcac cgagcaatct atgatgctga agcaactggt cacttagcat
     6781 ggatctttgt gaaagaggca atggacaatc ataacatgct ttatcatgat cagctaaatg
     6841 agcatatcgg agaaggagat tcttacaaaa gggctcgacc tttccatgta acgattttag
     6901 caaaaaatca ggcaggactg aaagatttgt tcaaactgat ttcaatgtcg aatgtcgaat
     6961 acttcgaacg cgtcccacga ataccacgct cccaattgaa aaagatgcgt gaaaatctat
     7021 tgatcggctc agcttgtgat aagggagaaa tattcgaagc catgatgcaa aaaggggtag
     7081 aagaggcaag aaaccgagca aaattctacg attatattga agttatgcca aaagcggtct
     7141 atgcgccttt gatcgagcaa gaattggtaa aaaatgaaca tgatttggaa gaaattatcc
     7201 aaaatttggt agaaatcgga aaaagtttgg ataaaatcgt tgttgcaaca ggtaatgtac
     7261 attatctgaa cgaagaagat gccatttacc gaaaaatttt gatcaattct atgggcggag
     7321 cgaatccgtt gaatcgtcat agtttgccgg atgtccattt ccgaacaacc gatgagatgc
     7381 taactgcatt tcacttttta ggggaagaaa cagcgaaaga gatcgtagta gaaaatacga
     7441 ataaaatcgc agatatctgc gaagaagtga ttccagtcaa agatgaactt tatacaccga
     7501 agattccagg ttcagaagat gaaatatcag aattgagtta cacaaaagca aaacaaatgt
     7561 acggagatcc gttacctgag atcattcaaa aacgattaaa aaaagagttg aattctatta
     7621 atggtaatgg cttctcggtt atttatctga tcgcccaaaa actagtgcat aaaagtaatg
     7681 aagatggcta tctagtaggt tcacgtggct ctgttggctc tagctttgtt gcgacgatga
     7741 caggaatcac tgaagttaat ccgttagccc ctcattatta ttgtccagag tgccaatatt
     7801 ccgagttttt tgaagatggt acgtatggtt ctggatttga catgccagaa aaacaatgtc
     7861 caaaatgtgg tgcacgctta aacaaagacg gtcatgatat tccatttgag acatttttag
     7921 gattccatgg agacaaagtg cccgatattg atttgaactt ctcaggtgat tatcaagcag
     7981 aagcccataa ctatacgaaa gtattgtttg gcgaagacta tgtttaccgt gccggaacga
     8041 ttggtacagt cgccgacaaa acagcatatg gctatgtaaa aggatacgaa agggacaata
     8101 atctgcagtt tcgaagtgca gaagtcgaca gattagcaaa aggcgctact ggagtcaaac
     8161 ggacaaccgg ccagcatcca ggggggatca tcgttattcc cgattatatg gatgtctatg
     8221 attttacgcc gatccaatat ccagcagacg atcaaaattc ggaatggaaa acgactcatt
     8281 ttgattttca ctcgattcac gataatgtat tgaaattaga tattctaggg catgatgacc
     8341 caactgttat tcggatgctt caagatttat cagggatcga tccacaaacg atccctacgg
     8401 atgacccgga agtgatgcgg atatttgccg gtcctgaagt acttggagta agtcaggaac
     8461 aaatttattc caaaacaggg acattaggta ttccagaatt cggcactcgt tttgttcgag
     8521 ggatgctaga agaaacgcat cctacaactt ttgcagaact actgcaaatt tccggactat
     8581 ctcatggtac agacgtatgg ttaggaaatg cggaagaatt gattcgacga ggagatgcga
     8641 cactggcgga agtaatcggc tgtcgtgatg atattatggt ttatttgatc catgctggat
     8701 tagatagcgg gatggcattt aaaatcatgg aaactgttcg taaaggacaa tggaacaaga
     8761 tccctgatga attgcgagaa acctatctat cggcgatgaa agaaaataat gtgcccgact
     8821 ggtatatcga ttcttgttca aaaatcaaat atatgtttcc gaaagcccat gctgcagctt
     8881 acgtattgat ggctcttcgt gtcgcttatt tcaaggttta tttccctatt ttgtattact
     8941 gtgcatactt ttctgtacgt gcagacgact ttgatctagt ctccatgtgc aaaggaaaag
     9001 atgctgtgaa acaagcaatg aaagaaatca cggacaaagg attagatgct tccgtaaaag
     9061 aaaagaatca actgacagtg ctggagttag ccaatgaaat gctggaacga ggattcaaat
     9121 ttggaatgat tgatttgtat aaatcggatg ccgttaactt tgttattgaa ggtgatacgt
     9181 tgatcgcacc atttagagct gtcccaagtt tgggaaccaa cgtggcaaaa caaatcgttg
     9241 aagcaagaaa agacggtcca tttttatcca aagaagatct tgccacccgc ggtaaagttt
     9301 caaaaacatt gatcgaatat atgaacgaca atggcgtatt gaaagatcta ccagatgaaa
     9361 atcaattatc gttattcgat atgctataag catctgtttt cctgtctgct tgtaatttta
     9421 agcagagtat ggtatagttc ttataggtaa tgatactaac tgtgagtgag cggatttttc
     9481 gctcactctt tttaatggaa ttacgcactt aattttttaa ggaggcgaaa cttttgagta
     9541 gcgtcgttga aacagtcaca gaaatggtga caccgatttt agatgaacaa aattttgaac
     9601 ttgtcgaagt cgaatttgta aaagaaggaa aaagctggtt cttacgagta tttattgaca
     9661 aagaaggcgg tatcgatatc gaagaatgcg cctttgtcag tgagaaactg agtgaaaaac
     9721 ttgatgcagc agatccagat ccgattcctc aagcttattt cctggaggta tcctccccgg
     9781 gagcagagcg gccattgaaa aaagaaagcg actatgaaaa ggcacttggt gattatgtcc
     9841 atgtctcctt ataccaacca gtagatggcg aaaaacaata tgaaggattt cttcaatcat
     9901 ttgatgctga acagcttaca ttgaaaatac gcataaaaac acgagaaaaa gaattgactt
     9961 ttgaccgaaa aaatattgca aaagctcgct tagctatcca attttaatca cggagaggaa
    10021 tcagaaaaaa tgagtaaaga aatgttaaat gcgttagacg ctttagaagc tgaaaaaggg
    10081 atctcaaaag aaatcgtgat cgatgcttta gaagcagcat tggtttctgc atacaaacgt
    10141 cactatggcc aagcacaaaa cgtcgaagtg gaatttgatc agaaaaaagg aaagatccat
    10201 gtctatgcgg taaaagaagt aacggaagaa gtgatggatt cacagttgga agtctcattg
    10261 aaagatgcac ttttaatcaa tccagcatat gagatcggtg atacgatccg ttttgaagta
    10321 acaccaaaag attttgggcg gatcgctgcg caaacggcta aacaagttat tttacagcgt
    10381 gtacgtgaag cagaaagaac gattatttat aacgaattca gtgcttatga aaaagacatc
    10441 atgcaaggaa tcgtcgaacg ccaggataaa cgttatattt atgtcaatct tggtaaaatt
    10501 gaggcagttc tttctaaaca agatcaaatg ccaaatgaat tttatcaacc acatgatcga
    10561 atcaaagttt atgtttcccg agtagaaaat acgtctaaag gtccgcaagt atttgttagc
    10621 cgcagccatc cagacctatt gcgccgctta tttgagcaag aagtaccaga agtctatgat
    10681 ggaatcgttg aaattgtcag catcgcccgt gaagctggcg atcgttcaaa agtggcagtt
    10741 cgctcaaatg atccaaatat cgatgcagtc ggtacatgtg tcgggccaaa gggacaacga
    10801 gttcaagcaa tcgtcaatga attaaaaggc gaaaacatgg atatcgtcga atggaatgaa
    10861 gatccagctg tattcattgc aaatgcattg aatcctgcac aagtcatgga tgtgatcttc
    10921 gatgagacaa atccaaaggc ctgcacagtt gtcgttccag actaccaatt atcgctagca
    10981 atcggtaaac gcggacaaaa cgcacgttta gctgctaaat tgactaacca taaaatcgat
    11041 atcaaatcag aatctgacat gacggaattt tatgaaaatc aagaacaaca aaaagaaaca
    11101 gaagaactgc atgatgaagc aatcgttcag tcagatttaa cagacgatga atatgaaaca
    11161 attgcattca acaatgaaac ggtcgaagaa aaaccagaag cttaacttta gtaaggaggc
    11221 aaagagatga aacaaaggaa aattccttta cgcaaatccg tggtttcagg tgaaatgaaa
    11281 cctaaaaaag agatggtccg aatcacccgt tcaaaagaag gggaagtatc gatcgatcca
    11341 actggaaaaa tgcctggacg aggagcgtat gtctcacttg agccggaaga agtacaacaa
    11401 gcttgggata aaaaaattct cgatcgagta ctcgaaacaa cattaacaga tgagttttat
    11461 caagaacttc ttgactatgt cactcaccaa aaagcacgta aagagttatt tggaaaatga
    11521 atacagttaa tcggcaaaaa gccatgaatc tcatcggtct agcgatgcgc gcgggaaaac
    11581 taatcacggg tgaagaactg accattgctg aaatccgcaa acaaaaagca aaattggtgt
    11641 ttgtggcaac cgatgcaagc gagaatacaa gaaaaaagat aaaagataag agttcatatt
    11701 atgaagttcc ttgctttgag ctattttctg aagcagaaat cacgcagatg atcggaaaac
    11761 ctcgcaaggt attcggaata atggatgccg gatttgcgaa gaagaccaag gagctaattg
    11821 aaggttagga aggtgattgc atgggcaaca aaagaatcta tgaattagca aaagaactca
    11881 aaaaatctag taaagacgtc gtggaaaaag cacaacaact tggcatcgat gtgaaaaacc
    11941 atatgggtgc gattactagc aatgatgaga agaaattgca acaagcgttc aaaaacccaa
    12001 gcacgaaaca acaagctgca caacaagcaa gcagaaaacc agccaatcaa cagccgaacg
    12061 atcaacgtaa aaaagaaaca acgaacaatc aacaaaaaaa taaaaataac cgcagttatc
    12121 aagatcgcgg tcaagggagc ggtcaagtga atcaaggaaa aaaaccaaca acaaaccaaa
    12181 ataatacggg aaataccagc agccaaaatc gtcaaggaac gagccaaggc ggcaatcaaa
    12241 accgtactaa caataacaac aaaccaaaca ataacaatcg cggcaaattt aataataata
    12301 accgtaatcg ttataataaa aaaggtaaaa aaggcaaaca gcaacaatca actaaaccag
    12361 ctgtaccacc acgcaaattc cgtgaattgc cagatgtatt agagtatact gaaggtatga
    12421 acgtagcaga tattgcgaaa aaaattcatc gtgagccagc agaaatcatt aaaaaattat
    12481 ttatgcttgg tgtcatggtc aatcaaaacc aagcactgga taaagatacg attgaactgt
    12541 tagcgacgga ctatggcatg gaaccacaag aaaaagtcca agttgacatt gctgatatcg
    12601 ataaattctt cgaggcagaa gaagtcgatc cagataaatt agtctcacgt ccgccagtcg
    12661 taacgattat gggacacgta gaccatggga aaacaacttt attggataca ttacgccatt
    12721 cacgtgtaac aagcggcgaa gccggcggaa tcacacagca tatcggtgcc taccagatcg
    12781 atattgatgg taaaccaatc actttcttgg atacaccagg acatgcggcc tttacaagta
    12841 tgcgtgcacg tggagcaagt atcacagata tcacgatctt agttgttgct gcagatgatg
    12901 gcgtcatgcc acaaacagtt gaagcaatca accatgccaa agctgcaggc gttccaatca
    12961 tcgtcgctgt aaataaaatt gataaaccag gtgcaaaccc tcaacatgtt atgcaagaat
    13021 taagtgagta tgagttaatt cctgaagcat ggggtggaga aacgatcttt gttgagatct
    13081 cagcgaaatt cggccaaaac atcgaagaat tgctggaaat gatcctgtta gtcgcagaag
    13141 tagaagattt aaaagcagat ccaacacaac gcgcaatcgg aacagtgatc gaagcacgtc
    13201 ttgataaagg taaaggtcct gtgtcaacct tacttgtcca agaaggaaca cttcatgttg
    13261 gtgacccaat cgttgtcggt aatacttacg gacgtgtccg tgtaatgaca aacgatcttg
    13321 gccgtcgcga taaagaagca ggacctgcaa cgccagtaga aatcactggc ttgaatgatg
    13381 tacctcaagc aggtgaccgt ttcgtagtct tcgaagacga aaagacagca cgtgcagcgg
    13441 gtgaagaacg cgcgaaacgt gcattattag aaaaccgtgc tgccacaagc cgtgtgactt
    13501 tggataactt atttgaaagc ctgcaagaag gcgaattgaa agaagttaac gtaatcatca
    13561 aagcagatgt acaaggttca gcagaagcac tggctgcatc attgaagaag attgatgtgg
    13621 aaggtgtccg tgtaaaaatc gtccattcag ctgtcggagc aatcaatgaa agtgatgtaa
    13681 ccttagcagc agccagcaac gctattatca tcggtttcaa cgttcgtcct acaccgcagg
    13741 caaaagtgca agctgatact gaagaagtcg atattcgtct tcaccgtatc atctataaag
    13801 ccatcgaaga aatcgaaact gcgatgaaag ggatgctaga ccctgaattt gaagaaaaaa
    13861 tcaccggtca aatgatcgtt cgtgaaacct tcaaagtttc taaagttggt acgattgcag
    13921 gtgcctatgt aacagaagga tatattcgta gagatagcgg tgtccgtgta atccgtgacg
    13981 gaatcgtaat ctatgaaggc caacttgcaa gtctgaaacg attcaaagat gacgtgaaag
    14041 aagtcaaaat gggttatgaa tgtggtgcaa tgattgaaaa attcaatgac atcaaagtag
    14101 atgacgtaat tgaaggattt atcatggaag aagtcaaaaa tgactaaaaa ctgataaaag
    14161 gaggccaatc attatggcta actaccgtga ccgccgagtc ggtcaagaaa tcttaaaaga
    14221 agtcaatgat attttgcgca aaaaggtccg tgaccctcgt gtggagaacg taacgatcac
    14281 agatgtgaaa gttacggggg acttacagca agcaacgatc tattacagca ttttatctga
    14341 cttagcatca gataagaaaa cagcacaaga tggattgaat aaagcatcag gattgattcg
    14401 tcgagagtta gggcacaatc taagtattta taagacacct gaattgttct ttgaacttga
    14461 tgaatcagtt gtctatggca accatatcga tgaattgctt cgcgacttga acaaagacta
    14521 atcaaaaact cccgcaaatc ctgtgaaatc aggctctttg tcaataagga ctgatgagtt
    14581 gtgcaaaatc aaatctgagt cagaatgaac cacattctgg ctcag
//
LOCUS       DADLIO010000066        13974 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.069, whole genome shotgun sequence.
ACCESSION   DADLIO010000066 DADLIO010000000
VERSION     DADLIO010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13974)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13974)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13974
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.069"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            140..460
                     /locus_tag="JOX41_002206"
     CDS             140..460
                     /locus_tag="JOX41_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449923.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            912..1112
                     /locus_tag="JOX41_002207"
     CDS             912..1112
                     /locus_tag="JOX41_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAY6449924.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            1259..4048
                     /locus_tag="JOX41_002208"
     CDS             1259..4048
                     /locus_tag="JOX41_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAY6449925.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            4095..4622
                     /locus_tag="JOX41_002209"
     CDS             4095..4622
                     /locus_tag="JOX41_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAY6449926.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            4643..5833
                     /locus_tag="JOX41_002210"
     CDS             4643..5833
                     /locus_tag="JOX41_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAY6449927.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNSEIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            5873..7171
                     /gene="asnS"
                     /locus_tag="JOX41_002211"
     CDS             5873..7171
                     /gene="asnS"
                     /locus_tag="JOX41_002211"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HAY6449928.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKITFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            7966..8640
                     /locus_tag="JOX41_002212"
     CDS             7966..8640
                     /locus_tag="JOX41_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAY6449929.1"
                     /translation="MKKRILFIGDSITDAGRYRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIVAVDFFSGDKNE
                     RKKSEK"
     gene            8637..8978
                     /locus_tag="JOX41_002213"
     CDS             8637..8978
                     /locus_tag="JOX41_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449930.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            9008..9367
                     /locus_tag="JOX41_002214"
     CDS             9008..9367
                     /locus_tag="JOX41_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HAY6449931.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            9561..9749
                     /locus_tag="JOX41_002215"
                     /pseudo
     CDS             9561..9749
                     /locus_tag="JOX41_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329861.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
     gene            9891..11975
                     /gene="cadA"
                     /locus_tag="JOX41_002216"
     CDS             9891..11975
                     /gene="cadA"
                     /locus_tag="JOX41_002216"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HAY6449932.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKKRNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTAEGLMTVNPEDVLIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     RAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDPTGIDPKKFMQYVASAEQFSTHPIAQSVLEGYAGPLL
                     PTANIQEFAGEGILAEVDGKQVLVGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGY
                     LVIADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDK
                     VQRLEEILQSNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQP
                     SKIAEAIHLAKKTLKIVKQNIVFAIGIKILVLSLGAFGFASMGDAVFADVGVTVLAVL
                     NAMRSLHVKNKR"
     gene            12286..13752
                     /locus_tag="JOX41_002217"
     CDS             12286..13752
                     /locus_tag="JOX41_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAY6449933.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
BASE COUNT         4635 a         2430 c         2974 g         3935 t
ORIGIN      
        1 aaaaagaggt tgtgacgtgg tcacgacctc tttttgacga ttatgataca aaaaacatca
       61 tttatgaaca aaatgtgaat aacgggcgtt cttgagatat gattttaatt gggaaaaact
      121 tatcgataag gaggtcttta tgaaaaaaag actgttatgg tgtttgctgt ttctatccct
      181 aagtttaaca agtcagccag tttttgctga agaaacacag cggtctccta ttacaggcac
      241 acgtctgtac aaaaatgttt atgtacagac aacagatctt gattctgcga ttcctgaaac
      301 agaagaacgg tctttgcagc caagatttgg ttacttttgg tactgtccga cctgtgatta
      361 tgaaagttgc tggcatttct tacattctac agctgcagct tttgctttta ctcatactca
      421 gaaatatgat ggacatcatc ctgttattta tgaggtatag atatgagcaa aaaagaaaaa
      481 ctaatctcgt tgatcgtatt ggtttgcctt gttcttctgg taactgtcat aggctatcag
      541 aaataccatg agaacatcag acctactaaa gaatcttccc cagcctcgac cgttgaaaca
      601 gaaccgataa gtagtcagaa agaataattt ttttagttta aagaagaaca tcagagcaaa
      661 aaaacaccaa ctgaacaata tgtcgtttat tttaaaaaaa gttcggtttt tcactttatg
      721 taatcgctga gaaaactttt tttaataaaa aaagtcgaaa aactctagct tttttgtaaa
      781 cggtatgata tactatagga gtagtttttg ttcggtaatc tgtggtagct tgtttcaaat
      841 aaacatcttc cagatataca ccattcaagt aattgcaaaa tatgtgttga tacacaagga
      901 ggatttttat tatggaaaca ggtacagtaa aatggtttaa ctcagaaaaa ggatttggat
      961 tcatcactgc agaaaacgga aacgatgtat tcgttcattt ctcagctatc caaggcgacg
     1021 gattcaaaac tttagaagaa ggccaagcag taactttcga tgttgaagaa ggccaacgcg
     1081 gacctcaagc aacaaacgtt actaaagctt aattaaccta tactaaaaaa taaacgccca
     1141 gacatttgcg tgtctgggcg tttttgtcta ttttctttaa aaagcgatga gagtattttt
     1201 ctgcactttg tagtataatt tcaaaagaac attagaggca ggagaagagg aagatatttt
     1261 gaaaccaaga acttatgcag tcgttgatat cgaaacgact gggacgaatc caaaagaaga
     1321 tcggatcatc caatttggct gcgtcatgat tgaatcaggt cggatcactt cacgtttttc
     1381 gatcgatatt catccagggc ggaagatttc aaaacaaatc cagcatttaa cagggatcac
     1441 gaatcaacgc gtccaaaaag cgccttattt cgaagatgtc gcccaaacga tttacaatct
     1501 tttggcagac accatatttg tcgcgcataa tatttatttt gattataatt ttttgaacca
     1561 tgaactcatg cgatgcggac ttcctagttt gaagatacca ggcatcgata cagtagaact
     1621 tgcacaaatt ttcttgccga cggaaccaag ctttcgctta gctgatttgt cagaaagcct
     1681 tggatttatt catgagaatc ctcatcaggc agatagtgat gccgaagtga cgggtcaact
     1741 tcttttgctg atcgaagaac ggatgagaaa attgccaatc atcacgttag agcagattgc
     1801 gcgattaagt agacacacag gtatggatac gagtcgtttc atttatcatg tgattgaaga
     1861 aatgaaagaa aaaccagagc cacttgatcc ctcattagaa atcgtcgatg ggctagcttt
     1921 gcagaaaaaa gaagtggaac tattcacatc cgtccattat ggcgagcgga catatccaag
     1981 aaaaaaacaa gcaaaagaaa aaatgtttgg taaaacactg atgtatcgaa aagaacagaa
     2041 cagactgatg aatgcggtct acgaccattt cacaaaagat gaatcaaaag atttgatgat
     2101 cgaagcagct acaggaatgg gtaaaacaat cggttatctg ctgccattga gttatttggc
     2161 tacacctgaa aaacccgctg tcatcagtac cgtttcgcta gttttgcagc agcagatcat
     2221 agaaaaagac attccattgc tgaatcaatt gctagatcag cccatacaac ctgtaattat
     2281 caaaagctat cgccactata ttgatttaca gcgttttaaa ggcacacttg tggaaccgcc
     2341 agaacaaaaa caatatgctt tgtatcaaat ggcggtctta gtttggctga cgcaaacgaa
     2401 gaccggtgat ttggatgaat tacatttaac aaatttgaac cattcattct ttgcagatat
     2461 cgcgcacaga ggtattggat ttttagcaag aaatcagtca ttttacgaac aagactttgt
     2521 tcgtttcttg caaaagaaaa tcaggcaaag taattttttg attgtcaatc atgcgttttt
     2581 aatacaagaa acacagcgaa aagaaccatt gcttccagct agtccatttt tgttgatcga
     2641 tgaagtacat catttgccgg aaatcgctga aaaagtaaat gacaaacgat taagtattaa
     2701 ctatttccat aaacaaatcc agcaattaga agaaccaaat cagctgtttg accgaataca
     2761 aagctattta ccgaaagaac atgaagcctt acgctggtta tcgatttatc gagaagaact
     2821 ttctgcgcta tgcgaagcac agatttgtat ggcagaagga ttaatgagtt tagtgagcgg
     2881 caagcaacct aacggacagt atccagaaga agtcatgatg acaaaagaga tgttggatca
     2941 gctgccactg gaatctggga cagccattga tcacctgcag cttttttatc aggagatcca
     3001 gcagctacag tcacaaatgc gtctgacttt tgagattatc caagaaagct ggacaaacca
     3061 gatgcggatc gatttagcaa gtttatatag cttatttgat caattagaca agcagtactt
     3121 gctgatggat caatggctgg aagactggcg agatcatttg atccattggt tcgttcctgg
     3181 gaacacagcg cagcagatga tttttcatct ccatgatttt caagcggcta tgttgccgtc
     3241 gactgtttgg tatcctcgat atgatcgtat tctttatatt ggaggaacgc tgaagatcgg
     3301 ccctaatcga cactatctct ctaagcggct tggcattgaa gcagcacctc ttaaagtgat
     3361 tgcctctcct tatgattatg agaaacaggc aaggatctat gtgccaaaag aggcacctgc
     3421 cgtccatcaa gtcagcaatc aagcatatat cgattattta gagacagcac ttacaggtct
     3481 gatcgaacaa gaagatcggc caatacttgt gttattcact tctcatgatg ttttgcagaa
     3541 ggtctatcag aaaatgcatc tgtctatgct agaaaaagga cgagaaatac tagctcaagg
     3601 gtttggcgga agccgggaga agcttttgaa acgcttcatt ttgtcagaaa aaagcgtatt
     3661 gtttggcgct gacagctttt gggaaggtgt agatttgcct ggggatgctt tgcagatcgt
     3721 tgtagtcaca cgtttaccct tcgataatcc gcttcgcccg atggtcaaag ctaggaacgc
     3781 ttatttagaa tcagagggga tcaatccttt ttaccaggaa tccgtaccta aagcagcttt
     3841 gaagttacgc caagcattag gtcgcttgat aaggacggag acagatcgtg gcgtattgct
     3901 tattttggat cgaagactag tcactgcaaa atatggtgca cggatcatcc atgcattacc
     3961 gaaaaaagta ccgatcaaag agctagctat ggaggaaatc tatcaggaca tccatgaatt
     4021 cttaaagaaa aatgaagaag gaagttagag gagctgtctt ttttcataat taaaatctgc
     4081 tataatgaaa aggaatgaag ataaaggagc gacgaccctt gaagaaaaaa cagacaaagg
     4141 aaaaaacgat taatcgcgtg ttacttggct tgatcgtatt tttattagcg gtcatcgtga
     4201 tcagctcgat tttttacttg cgttccagtc gtccggcggt gcaggcgaag aaagaagcag
     4261 tagaaatcgc aaagaaatat gcaaatcttg aggaagccga tcatttttat tggtttactc
     4321 gaaagaagac atacttttca ctgacaggta caaatgataa aggaaaagaa atcgccgtta
     4381 tcattcctaa atctggtgaa aaagtaaaag tattggatca aacaaaggga ctgactgaaa
     4441 acgaagcaaa acagacaatt gctgcggccc atcctgaaat ccaaatcgaa aaagctgctt
     4501 tagggatgta tgatgatcag cctgtgtggg aagtagtagg aaaagaaaca aatgggaaac
     4561 tgaattatta cctgattggc tttgaatctg gagatgaagt caagacaatc aagggaattt
     4621 aaaaggtaaa ggaatgaatg ggatggagtt atcaaaaaga acaaaacgat tagaaccgtc
     4681 tgtcactttg gcagctgcgg caaaggccaa ggcattaaaa gcaaaaggca gagatgtgct
     4741 gagtttgact gtgggagaac cggattttgc gacaccagaa aacatccaag aagcagcaat
     4801 cgaagcaatc cgcaatggga aagctagcta ttatacacca acagcaggaa tcccagagct
     4861 tcgacaggca atcgttgatt atctgaagaa aaactatgga cttgtctatg aaccttcaca
     4921 aacagtcgta acagacggag cgaaatttgc tttgtatacc cttttccaaa cgatccttga
     4981 cccgcaagat gaagtcatca ttcctgtgcc ttactgggtc agttacggtg agcaagtaaa
     5041 actggcagaa ggacttcctg tctttgtgaa aggggaagaa tccaatagct ggaaagttac
     5101 tgttgaacag ctagaacaag cacgttcaga aaaaacaaaa gccgtaatca tcaattctcc
     5161 atcgaatccg actggaatga tttatagcaa gaatgaactt caggcaatcg gtgaatgggc
     5221 agtaaaaaat gatattttga tagttgctga tgatatttat ggtcgtttag tttataatgg
     5281 caatgagttt actccaattg caacgatttc agaagcaatc aaaaatcaga ccatcatcat
     5341 caatggcgtg tctaaaacat atgcgatgac aggctggcgc attggttatg cggtggggaa
     5401 ttctgagatc atcaatggaa tgattgctgt tgcttcccag tcaaccagta atccgacagc
     5461 agtcagtcaa tatgcagctg ttgaagcatt gaaaggtgag caagatacag tagaagaaat
     5521 gcggaacgcc tttgaagaac gcctgaatac gttatatccg cttgtggcag aactgccagg
     5581 tgtttctctt gaaaagccgc aaggagcttt ctatcttttt cctaatgtaa aagaaacgct
     5641 acgcatgtgt aaatatgaaa atgtcacaca atgggtagaa gatcttttag aagaaacagg
     5701 ggtagcgctt gtgactggcg aaggctttgg ggcaccagaa aatgtccgca tgagttatgc
     5761 tactgatcgc gctacgttag aagaagcggt acgcagaatc aagcaattta ttgagagtaa
     5821 aagtcaaaat taatcctgaa gaaattcaag gaatataaaa ggagagtcat acgtggaaca
     5881 aattcaaatc atcgattcga aaaaccatgt gggagaaaca gtaacaatcg gcgcttgggt
     5941 cgcaaataag cgatcaagcg gaaaaatcac atttttacaa ttaagagacg gaacagcctt
     6001 tttccaaggt gtagttgtaa aaagcgaagt gtcggaagaa gttttccaaa cagctaaaaa
     6061 tctacaccaa gaaacatccg tgttagtaac tggagaaatc cgtgaagaca gtcgttcaaa
     6121 atttggttat gaaatcggaa ttacaaatgt ggaagtggta agcgagagcc acgattatcc
     6181 gatcacacca aaagaacacg gaacagactt cttgatggat catcgtcatt tatggctgcg
     6241 ttcttcaaga caacatgcga ttatgcagat cagaaatgaa atcattcgtg caacgtatga
     6301 attctttaat caacatcatt ttgtcaaaat tgatccgccg atcttgactg gttctgcacc
     6361 agaaggcact acggatctat tcgaaacaaa ttactttgat caaaaagctt atttatctca
     6421 aagtggccaa ttatacatgg aagctgctgc tatggctttc ggaaaagtct tttcattcgg
     6481 tccgactttc cgtgctgaaa aatcaaaaac acgacgtcat ttgatcgaat tctggatgat
     6541 cgaaccagaa atggctttca ctcatcaaga agaaagttta gaagtacagg aacaatatgt
     6601 agcattctta gtacaaaatg ttttagatca ttgcgaatac gcattagatg tactaggacg
     6661 agacaaagaa gtcttaaaaa cttatacaaa attgccattc cctcgtatta cttacgatga
     6721 tgcaatcgaa ttactgaaga aaaatggatt tgatgacatc gaatggggcg aagactttgg
     6781 ttcacctcat gaaacgttca ttgcgaattc attcgaacag cctgtcttta tcctaaacta
     6841 tccaaaagcc atcaagccat tctacatgaa accacatcca acaagagaag acgtggtaat
     6901 ttgtgcagat atgatcgcac cagaaggtta cggtgaaatt attggcggaa gcgaacgggc
     6961 aacggactat gatttcttgc tagaacaaat ccgtaatcac ggtttggatg aaaaagaata
     7021 ttcatggtat cttgatctac gtaaatacgg ttctgttccg cactctggtt ttggtctagg
     7081 tcttgaacga acagtcactt ggattgctgg tatcgaccat gtacgtgaag ctattccatt
     7141 cccacgtttg ttgaaccgaa tttatccata agaggttgtg cgcctgccgt tcagctccga
     7201 gtcacaagga gtaatttcaa aaaacagttt ttcatgtttg atgactattg tgacttgtgg
     7261 ccggagagca acgtttattt aaaaaaaaga actgcgaact ctcgcagttc ttttttttaa
     7321 atacgggata atggaagttt ccagcagaca agagaagaaa gcaaaagaaa ttgctatttg
     7381 attcacaagg ttctataacg aaatcgcaat caatcaaaca tttacaaaga aggtaattca
     7441 aatggaaatc tgatttgatg atgcttctgc tgttgaaata aagcagcatc tagcacctga
     7501 aaacaaacta atagtaacat tcgaagatgg agtaggtccg tattttcagc atgcaataat
     7561 ccatatgtaa gttcaattca cccttgaaat catcggacca gataaagtta tgaccaatct
     7621 atcccaagca atctagaaga gatattagta aagggacatt tactagaagt cttagatgag
     7681 cctataaata tatgtttcga tggcgtcatc agtggtctga ttgacggaag cttgggtgtg
     7741 atcgatctct ctggaccaaa caacgaagga atcaagggga atccggcacg ttaagaaaaa
     7801 aatagcataa aaaactagac acttgatgag cgttcattca attgtttgaa ggaactaggc
     7861 tggtgtcatt ttttatacat atattttctc tttcgtcttg atagggctta tgggataata
     7921 taaggaagaa aatcatcgtt ttattcaaaa aggagttttt gacaaatgaa aaaacgtata
     7981 ttatttatcg gtgatagcat tacagacgca ggaagatacc gagcagaagc aactgatcta
     8041 ggtaaaggtt atccactttt gattgccgga aaactaatct cccaatatcc aacgatggaa
     8101 tttgaatgca tgaaccgtgg gataggagga gacaaaattg cagatctgca agtacgctgg
     8161 caagaagatt gtttagcttt acaacctgac tatgtatcga ttttgatcgg aatcaatgat
     8221 acctggcata atactagcga tcaggctata ttcggaactg agaaatctgc tcagcaattt
     8281 gaatccgttt atcgaaaatt actaaatgaa cttcaaacag cggaaatctg caacatcatc
     8341 ttgatggagc cgtttgtact tcctataacc gacgaccgtc atggctggcg taaagactta
     8401 gaccctaaaa tccaaattgt tcgtaaactt gctaaggaat atggcgcatt gctggttcct
     8461 ttagatggta tattcaatgc tttagggatt gcttatggtt tttcgaaata tacaagagaa
     8521 gatggggtcc acccaacgat tggcggacat gagatcattg cacaaagctg gatagatgca
     8581 attgtcgcag tcgatttttt tagtggagat aaaaatgagc gaaagaaaag tgaaaaatga
     8641 tggaaataag gtgggcagta aaagaagatt tacctcaaat caatcagctg attactgatc
     8701 atccagaatc attcgtaaaa gcaaaaacgg cagctgacct aaatgataag aataaactat
     8761 tgctcgttgc tgtaacaaaa gaaaaacgga ttatcggatt tgcgcaagcg gacgtgcaac
     8821 agtcagaaga acgattggat cagcgaccat caggaaaact aatccaacac acattagtaa
     8881 caaaagaaaa tacggaagaa atccaaaaaa aatttgcaga atacttgatg ctggaagcta
     8941 aaaaaagaag aataaaatca atttttgccc agttttaatc aaaaacagta atagaaggag
     9001 aaatacaatg agttgtttag gaaatgtcat ctggtttata ttcggcggac taatcggtgg
     9061 tcttagctgg ttagcagcgg ggatactttg gtgtatcacg atcataggta tcccaatcgg
     9121 tatgcaatgt tttaagatcg cctccctttc ttttgcgcct tttggcaaag aagtaattta
     9181 tcaccagtct ggcatgtcat tgatcgttaa tatcatctgg ctgatcgttt caggcctacc
     9241 aattgctctc gcacatgtcg tcagcggcat ccttctatgt atcacgatca tagggatacc
     9301 ttttgccaag caatctttca aacttgctcg attggcgttg atgccattcg gtgcagaaat
     9361 tgtataaaag agaataataa aggttagata aagcatagag ccaggtggga tacatgtatt
     9421 tcacctgact ctatgcgttt tcctgtataa gttcttctat gtgactttta cgtcttttat
     9481 ttatatgggg ttactgttta tggaaagttg aaataatttt cattaaagaa ctctttctat
     9541 atttttgaaa gcgtagtgga gcttcgtata tctgggaagg acattttgca gggattgaaa
     9601 aaagatattg tcctatcgaa aaattaatga atttagacaa attgccagca acaggcttca
     9661 aacttagttg ctatcctgtc aagatcaaga aggcaagtgc gggttggata agagcagtgg
     9721 caatgatcga agagaaaaag aaagaataag ccaaaacatc tgtatggaag aaattttccg
     9781 atgcagatgt ttttcatttt ttctttcgga taccttgaca tatgaataac cattcattta
     9841 taattagtta tgaagagata ttcatatgtt gaggcgagga ggtcattaaa atgaaaagtt
     9901 acagattaga aggtttagat tgtgcgaact gtgcaatgaa aatcgaaaaa ggagttcaga
     9961 aaatcaatgg agtcaaggaa gcaacggtaa acttcacttc tggaaaacta acgattgacg
    10021 cagaggaaga tcatttggct acgattgaac aagaaacaaa aaaagtagtg aaggaattag
    10081 aaccagatgt caaagtaaca gaaatagata aggaaaaagt atctgaacat ggaaatgaaa
    10141 aaaagagaaa tacgctgttc cggattttat tttcccttgc aggtatcgct ttattgctat
    10201 tatttgattt taatgaacca attcgcttga tagggtattt attgatttat ctgctgatag
    10261 gatatgatgt agtgaagaag gcagtgatga atatcgtcaa aggaaaaatc tttgatgaga
    10321 attttcttat gtctgttgct acgattggcg ctatgttgat cggtgaatat ccagaagccg
    10381 tagcagtgat gctattttat caaatcggcg agtatttcca aggattggca gtcagtcatt
    10441 caagaaaatc gattcgcgaa ttgatggcga tccgtccaga aacagctcac gtgcagacgg
    10501 cggaaggatt gatgaccgtg aaccctgaag acgtgctgat cggtcagttt gtacttgtga
    10561 agcctggtga acgtgtaccg ttagatggaa cgatcatcga aggagaatca ttagtcgata
    10621 cgtcagcact tacaggagaa tcagtcccta aatctgtata tgttggtgaa acagtattaa
    10681 gcggatttat caataaaaat aaaccatttt tagttcaagt agaaaaatct tatgaaaatt
    10741 ctactatcag caaattatta gaattagtag aaaatgccag cagtaaaaaa gcaccagctg
    10801 aaaatttcat tactaaattc gcgcgctatt acacaccagt cgttgtagga ttggccgttt
    10861 tattagctgt tttacctcca cttgttgttt ctagagcggc gttttctgaa tggatctatc
    10921 gagcattgac atttttagtg atctcatgtc catgtgcatt agtgatttcc gtgccactta
    10981 gtttctttgg cggtatcgga ggagcaagta aaatcggtgt attagtaaaa ggttcaaatt
    11041 acttggagtt gcttgcacaa actgagacag tggtattcga taaaactggc acattaacga
    11101 aaggtgactt ttcgatccag acgatcgatc caacaggaat tgatccaaag aaatttatgc
    11161 aatatgttgc aagtgcagaa cagttttcta cacatccgat tgctcaatct gttttagaag
    11221 gctacgcagg tccgctttta ccaacagcta atatccagga atttgcaggt gaagggatct
    11281 tagctgaagt tgatggcaaa caagtattag taggtaatca caaattgatg gaaagatttg
    11341 aaatctcttt tccttcaagt caagaaatcg gtacattgct ttatctagcg atcgatcaaa
    11401 gttacagtgg ttatcttgtt attgcagata ccttgaaaga agatgccgta gacgcattgg
    11461 ttcaattaaa acaggctggt gtgaaaaaca cagtcatgtt gacgggcgac tcgaaaaaaa
    11521 ttgctgatca tatcgggaag caagtaggcg tggacaagat atatagcgaa ttgcttccag
    11581 aagataaagt gcagcggtta gaggaaatct tacaaagtaa caataaaaag accgcatttg
    11641 tcggagatgg aatcaacgat gcaccggtgc tagcaagagc agatgtagga atcgcaatgg
    11701 gtggattggg aagcgatgct gcaattgaag cagcagatgt agtcatcatg aatgatcaac
    11761 catcgaagat tgcagaagca atccatttag caaagaaaac attgaaaatc gtcaaacaga
    11821 acattgtctt tgctattggg ataaaaattt tggtactttc cttaggtgct tttggttttg
    11881 catcaatggg agatgcagta tttgcagatg ttggggtgac agtattagct gttttgaatg
    11941 ccatgcgaag cttgcatgta aaaaataaac gttgatcaat gaagaggacg aatgaacgtc
    12001 ctcttttttt tatatccttt tcttaatgaa aaatgtaaag aaaatagata ggattataaa
    12061 ataactaatg tttttaattt tgcagaaaat tcaaaatagc ttgaaattca ataaggtcaa
    12121 tgaaataaaa gaaaataact tatttttttg atggaaaaaa tatgaaaaaa cgatgtgtat
    12181 taaataaaag aatacacaca taaaataaca ctgtcttgta agtttgttaa aaattgaata
    12241 tgattacatc tggataacaa atttttatca taaaggagag aacgaatgaa caacaaacaa
    12301 ttacgctggt ttactgttgc gttaattgca tttaacatgg tttggggcat ggggaatgta
    12361 gttaataact atgctcagca aggagtatca gttgtcacct cttggctatt gattttggcc
    12421 atttatttta ttccatacgc attgatcgtt ggacaattag gatcagcctt caaggatagt
    12481 aaaggaggcg tcagttcatg ggtcgaaaat acgacatcta ataaacgact ggcatactat
    12541 gccgcttgga cttactgggt cgtccatatt ccttatttgg cacaaaagcc tcaagcaatt
    12601 ctgattgctg gtggttgggc agtccaagga aatggaaata tcgtaaatac gatgtcagta
    12661 caaatggtag cagttatttc acttattata tttcttgcct ttttatattt atcaacaaaa
    12721 ggactttcta ctttgaaagt gattggcgga ctggccggaa cagcgatgtt cgtcatgtcg
    12781 atcttattta ttcttttagc tgtaacggca ccgttcatca atccaacgat ggaatttgcc
    12841 acaccacata tgaatcaagt gaaaacatat attccaacat ttgatttcag ttatttcaca
    12901 accgtttcga tgctagtatt tgcagttgga ggggcggaaa aaatatcccc ttatgtcaac
    12961 tctacaagaa atcctgcaaa ggaatttcct aaagggatga tcttcttagc agcaatggta
    13021 gggatttgtg ctgtattagg ctcagtcgca atgggtatgc tgtttgctag cgataatatc
    13081 cctaaagact tgatggcaaa tggggcatac agtgcttttc aaattttagg taattactat
    13141 ggtatcggta actcattgat gatcatttac gcattgacaa acatgattgg acaaatctcc
    13201 gcattagcct tttcaattga tgcaccacta aaaatcttgt tagcagatgc ggatccagaa
    13261 tttgtaccaa actggctacg taaacgtaat cgtaaaggta cattggtgaa tggttatctt
    13321 ctgacaggta tactagtagg aatcattatt ttgttgccga tctttggtat caaagatatg
    13381 aatgaattag taaaatggtt gacgaacttg aactcagttg tcatgccaat gcgttaccta
    13441 tgggtgttct tggcatatat gatgttgaat aaagcttata agaaattcaa ttctgaatat
    13501 aaatttgtta aaaatccaaa aatcggtttt atctttggtg cttggtgctt tgccttcact
    13561 gcgtttgcat gtatcctagg aatggtgcca aaagtagatt atactgctga tcctaaagca
    13621 tggtggttcc aattattcac gaatatcatc acaccaattg tcttgatctt attaggtatg
    13681 atcttgccag caattgctcg tcgagacaaa aacaaagaaa ttactgaacc agaaacagtg
    13741 gttcagcctt aaaatagaaa tacttgttac aagaggttgt gacagaagct acttctggaa
    13801 caccgtgaat cagaggttgt gaaaaagctg tcctgcatca agtaataaga acagccaaac
    13861 aaaaatagct cctcatattt tgccgttttt tgagctaatg ctgaaggtca gctgattgaa
    13921 caccatttat tcgaaacaag ggactttgac acgacttttg tcacagtccc ttgt
//
LOCUS       DADLIO010000067        13935 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.070, whole genome shotgun sequence.
ACCESSION   DADLIO010000067 DADLIO010000000
VERSION     DADLIO010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13935)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13935)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13935
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.070"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            131..505
                     /locus_tag="JOX41_002218"
     CDS             131..505
                     /locus_tag="JOX41_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAY6449934.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="JOX41_002219"
     CDS             complement(619..1248)
                     /locus_tag="JOX41_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAY6449935.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="JOX41_002220"
     tRNA            complement(1382..1454)
                     /locus_tag="JOX41_002220"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
     gene            1668..1741
                     /locus_tag="JOX41_002221"
     tRNA            1668..1741
                     /locus_tag="JOX41_002221"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1702..1704,aa:Asn,seq:gtt)
     gene            1696..1845
                     /locus_tag="JOX41_002222"
     CDS             1696..1845
                     /locus_tag="JOX41_002222"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449936.1"
                     /translation="MTVNHDVVGSSPTAGVNKAYAKKKKSNHLGFFFFYYYDESSFLF
                     LSRML"
     gene            2338..3666
                     /locus_tag="JOX41_002223"
     CDS             2338..3666
                     /locus_tag="JOX41_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAY6449937.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTVVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3868..4701
                     /locus_tag="JOX41_002224"
     CDS             3868..4701
                     /locus_tag="JOX41_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HAY6449938.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4717..5454
                     /locus_tag="JOX41_002225"
     CDS             4717..5454
                     /locus_tag="JOX41_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HAY6449939.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5609..6577)
                     /locus_tag="JOX41_002226"
     CDS             complement(5609..6577)
                     /locus_tag="JOX41_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HAY6449940.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6809..7642
                     /locus_tag="JOX41_002227"
     CDS             6809..7642
                     /locus_tag="JOX41_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HAY6449941.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7676..8515
                     /locus_tag="JOX41_002228"
     CDS             7676..8515
                     /locus_tag="JOX41_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAY6449942.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8541..9101
                     /locus_tag="JOX41_002229"
     CDS             8541..9101
                     /locus_tag="JOX41_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAY6449943.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9300..11021
                     /locus_tag="JOX41_002230"
     CDS             9300..11021
                     /locus_tag="JOX41_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HAY6449944.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11186..12328
                     /locus_tag="JOX41_002231"
     CDS             11186..12328
                     /locus_tag="JOX41_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAY6449945.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12344..13555
                     /gene="thiI"
                     /locus_tag="JOX41_002232"
     CDS             12344..13555
                     /gene="thiI"
                     /locus_tag="JOX41_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HAY6449946.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
BASE COUNT         4757 a         2304 c         2836 g         4038 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt acttgattcc ggcatagctc
     1681 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactgccgga
     1741 gtaaataaag cttatgcaaa gaaaaagaaa tccaatcact tgggtttctt tttcttttat
     1801 tattatgatg aatcaagctt tctgtttttg tcacgtatgt tgtaatcttt acgaaagagt
     1861 agagttggct actcataatc aaccatactt cccatcatcg ctaaatacga aataaatcag
     1921 cattcctaca ccaatcaaag cacaagctgc accaagaaaa gggatgacat tcccaaagtt
     1981 atctgtattc ataagtatgc caccacccac aaacaaaaag ccgccagcaa tcaggttttt
     2041 cattttattc atctcctttc ttacgttata gtatttcctt ctttcaatga gtattttgaa
     2101 agctatctta ttgtatgatg ttcttctagg cctcttcttt attatacagg ccattttcgt
     2161 tatctcatag aaatattcct ttttatctga aaactattgt ataccgtatg acatttttct
     2221 tcatgaagtt gtaagtatat tctcattcaa atgaaaattt catcatagaa gagattgtat
     2281 ttctaaattc ttaagagtaa aatacgaagt ataacttgga tttggaagga tgattggatg
     2341 aaagctatta cgcctgatat gacaacaaaa tttaacaaac agtttcaagc aaatatcaaa
     2401 cagcaggcat tgcagcgggc agttgtgaag aacggaatta ctgcttctgc tgaaaatgtt
     2461 tcagcacatg tggagaatac accggtattt tctatagatt tggctacggg gaaagtggct
     2521 aatcaaatgc aatcggggcg ttgctggatg tttgctgcac tgaacacatt ccgtcataag
     2581 atgctgaatc aattccattt aaaagagttt gaattatcac aaaattacac ttttttctgg
     2641 gataaatatg aaaaggcaaa ttatttctat gaaaacatca ttgcaacagg aaaagaggca
     2701 atcgatagcc ggaaagtagc tttcttactc gctactcctc aacaagatgg cggccaatgg
     2761 gatatgatcg tttcattatt ccaaaaatat ggcgttgtgc ctaaatcggt gatgccggaa
     2821 agtgcgaata gttcaaattc tcgagatttg aataactact tgaacaaatt actgcgtaaa
     2881 gatgcagtag tgttacggaa aatggttgct caaggagaaa cattagacgc tattgaagaa
     2941 aagaaagaag aaatgctaga aagcatttat aacttcttag ctatctcatt aggaacacct
     3001 ccaaaagaat tcgattttga gtaccgcgat gaagaaaaga actatcatct tgaccgagga
     3061 ctgacaccac aaatttttta tgataaatac atcggtgtaa aattagatga ttatgttagc
     3121 gtgatcaatg caccaacaaa agacaaacca ttcaatcgtt cttatacagt agagatgcta
     3181 ggaaatgtcg ttggcgggaa agaagtcaaa tatctgaatg ttgatatgga aactttcaaa
     3241 aaattagcga ttgctcagct tgaagaagga gaatctgttt ggtttggttg tgatgtaggt
     3301 caatcttcta ctagaactag tggcatcatg gccttagatg cttattcaat ggatgatcta
     3361 tttgatacgg attttacaat gactaaagct gaacgtttag attttggaga aagtctgatg
     3421 acccatgcga tggtattgac cgttgttgac ttagtagacg ggcaatcaac aaaatggaaa
     3481 gtcgaaaata gctggggcga aaaagttgga aagaatggct tctttgttat gagtgatgcc
     3541 tggatggacg aatatacgta ccaaatcgtt gtaagaaaag atttattgac gaaagagcaa
     3601 ttaaatgcgt tcaatgaaga accaattgtt ctatctccgt gggatccaat gggtgcttta
     3661 gcatagacga gtatttcaat gaagagtatg tagtaaagat aaaaagagct ggcttaagcc
     3721 agctcttttt atctttaaag tccattccct gttttttatg gtccctgtgc tataattcta
     3781 aataaaggat aaggattgga aataatcctt ttatcattaa aaatatgatg acgaagtaga
     3841 ataaaattgg gagtaggggg gaaagtcatg gatatccaaa ctgttttatc tgatctgaaa
     3901 ttaaatggta aagtgattcc agttgttggt ggcgatgtta atcagaccta tcgtataaaa
     3961 accgaacatc gtgcttattt tttaaaaatc catccgaatg taaaaaaagg attttttgaa
     4021 gcagaagtag acggattaaa agaactgtca gcattcgtac gtgtaccgga tacgtatatg
     4081 ctaggtgaaa caagtgaagg cgcttatttg ttaatggaat ggatcgagcc gggaaaaggg
     4141 gatcaacgag atcttgctgc agctttagct aatctccatc agcaaacagc gccacaattt
     4201 ggttttcgta aagataacta tttgggtaca cttgttcaga aaaattcttt tgaagaagat
     4261 tggtggactt ttttctttaa agatcggctt gaatcccaga tttctttggc agaagaaacg
     4321 aatcgatgga atgtacagcg tcaagaaaag tatctgcgat ttaaagaacg tgtattgaaa
     4381 tcggttgaac caaaaaagat cactccacgc ctcttgcacg gagacctgtg gagtggtaat
     4441 gtgttctttg accagcaagg gcatccagtt tttgtcgacc cagctgtttc ttatgggaat
     4501 cgggaacaag atattgcaat gagccagtta ttcggtggtt tccgaccgga atttttagat
     4561 gcttatcaaa ctatatttcc attagaaaag ggatggaaag accgactgcc gatttaccag
     4621 ttatattatc ttttggcaca tttgaatatg tttggagaaa gttacggttc ccaagtagat
     4681 caattactag aaaattttta agaggagggc gtgtttttgg caaaaaaata taccaaaaag
     4741 catgaagttt catattatga gtgtgacatc aaccaaacga tgacatttcc ttcgatgtta
     4801 ggagtagtta tcaaaacgtc tgaagatcaa agcgaccagt tgggaagagg cagtgaattc
     4861 gtcaatagct ttggacttac ttgggtcatc acgaattatt ccatggagat taatcgtctc
     4921 cctagagtcg gtgaagtaat ctcagtaacg actcaagcca tggagtacaa taagtttttc
     4981 tgttatcgga acttctggat ccatgatgaa gatgggaaag aattagtcaa aatagaatct
     5041 gttttcgtat tgatggattt tgtgaatcga aaaatgagca gtgttaatga agagatcatt
     5101 gctccttttg agagtgagaa gatcaagaaa atcaagcgtc aggaaaaaat tgaaaagatt
     5161 gattcgggct tcatgttgcc atatcgtgtt cgtttttatg atatcgatag taatcagcat
     5221 gttaataatg cgatgtattt taattggatc attgacgtat taggatatga ctttttgact
     5281 acgcatgttc cagaaaaagt aattattcga tttgataaag aagtagagta cgggaatgag
     5341 atcgaaagcc attttgaaca aatccctatc gaaaatggtg tcaaaacaaa acatgaaatc
     5401 cgaatgcaag aacagctgta ttgtgaagca aatattatat ggaaaaataa ataaaaaaga
     5461 ggttgtgaca gaagggggca acttcaagaa ataagaagaa atttacgaaa attgtttctc
     5521 aaatttttgt aaattttcga cttagttttc gaagaagcta tttttgtcac agcctctctt
     5581 tttaagttta gctattagat aatgatgttt agttttggat aaacgaaatc aattcttcac
     5641 ccgacaaacc atagtttaca gcaatcaata gttttaaacg tgctttttga ctattaatac
     5701 tgttacagaa aataatcccc attttttcta gttcttttcc cccgccttca taatcataaa
     5761 caggctctgc gattccattg aaacaacgag aaacaagtac tacagggatt ttttggacaa
     5821 gaagcttttc caaagcagct aaggcttgtg gagggagatt ccccgcacct aaagcttcga
     5881 ttaccaaacc gtctactttc gtatgggcga tggcttccaa taagtcccct tgcatcccag
     5941 catatgcttt aacgatcggg atagtcccat ctacagcgga aatgtccagt cgctttgttt
     6001 ctaaaagttc ctgcaagaat aaaattcgat tcttagttac taagccgatg ggacccaatg
     6061 taggtgttcg gaaagtagca acatttgtgg tatgggtctt tgtcacgtag cgtgcagaat
     6121 ggatctcatc gttcatgacc accaaaaccc ccttatctag cgcttcttca caacttgcga
     6181 cacgaatcgc actttcaaaa ttataaaggc cgtcacttcc aagttcatta cttgaacgca
     6241 ttgccccagt caaaacaatt ggtaatttgt tgccaatcgt tgtatcaaga aaaaaagcag
     6301 tttcttctaa tgtatctgta ccgtgtgtga tcaccactcc ggatatacct gatgcataag
     6361 cggacaagat acgttctttt aataccaaca tgtgagaagg catgatgtgt ggtgagggaa
     6421 gattgaagat atcttcaact aataattcta catgcttggg gattgtgatt tctgcatcta
     6481 ataatgggtt tgccacatca ggactaacac cgcccgtgag catgttttct ttcatggcga
     6541 tcgttccgcc ggtgtgtagt acaagtattt ttttcatttt acagacttcc ttacgaataa
     6601 ttttgcatag ccgttaaatc ttattgtata ctatataaaa gagttttgct atcagtgaag
     6661 aataacgaat agcctaactt atcataaaaa agctgacctt attaaaatgg aaaagactca
     6721 accttgacct cctaatacaa tggagtatct ggttgagttt cttttacaag aaagcagcca
     6781 aggaaatcaa tcacgaaggt ggccggaaat gatcagaatc ggattaacat cgtttaaaga
     6841 acatgacaaa ttaactggta aaaagaataa cactctttat gaatatgcag ggtttctacc
     6901 cttagtggaa ttagatactg cctattatgg aattccccga aagtcctcag ttgagaattg
     6961 gataagtgaa gtacctgaat catttcgctt tgtagtcaaa gtctatcaag gaatcagcgg
     7021 tcaaggagac tggaagcctt attatcagac cgaagaagag atgattgcgc attttttaga
     7081 tgttatgtcg ccaatggtag atgctggaaa gatgttttgc tttttagtcc aattcccctc
     7141 atcattcaaa tgtacgaaag aaaatgtcca gtacttgcgc aaacttagaa agtggtttga
     7201 gggttatcct gtttctatag aattgcggga ttattcttgg tacagcgatg aatttcttga
     7261 acgtacaaga aactttatgt ctagagccgc tttttcttta gccatcatcg atgagccaca
     7321 gttgctgaat acaacgattc cttttgatcc atttgtcacc aatccgaact ttgctctttt
     7381 tcgattccat ggtaggaatg cgcaaggatg gcaagcaaat gataaagagt ggcgtaaaaa
     7441 aagaacgtta tatcgttatt cagaaaaaga actgcaagaa ctagcacatg aagtcaaagt
     7501 agttgattct aagacaaaag aggtaggtgt gatttttaat aataattctg gtggtgatgc
     7561 ggctgaaaat gcattagcac tgcaaaaaat attaaatatc aagccagatg gactcaatcc
     7621 aacccaaatg gatctgtttt aagggcttat tttattcaag aaaggggcga agtctatgat
     7681 caaagctatt ttttttgata ttgacggaac attggtcacc aatcgttcaa aagcgttgga
     7741 atcaacaaaa caagcaattg aatatgctcg gaaaaacggc attttatgcg gtgtagcaac
     7801 ggggcgcagc ccagtaaaga tcaaagaaat cattgatgaa ttggaattag atatgtatgt
     7861 cgtgtataat ggtcaactgg tttttactgc agatcgcacg attatcgacc acccttttga
     7921 acaaaaagta ttggaacata ttgttgaatt tgcagatgag aaccatcgac aaatcgtttt
     7981 tggtgcgaga aatcggttag atggatcaac gacgatgcta ttaggacaat cgatttttat
     8041 caagcgacta gtcagctttt taccgcgtaa attcccggta cgtctgatga aaaaaatcct
     8101 ccaggttttt agccctcacc gacaaaagga tcgttatgaa acgttagaga tattaaaaga
     8161 accaatttat caatgtatat tgctcagtcc ggagtcagaa cagaaaaagt tagaacatcg
     8221 ctttcccgag tgtacgtttc agcgttcaaa tacgtatact gtagatatca tcccaaaagg
     8281 tggttcaaaa ttactaggca tccaagcttt cgcaaatgct gtcgaaattg aaatggaaga
     8341 aattatggca ttcggcgatc attacaatga tatcgagatg ctgaaaggtg taggaattgg
     8401 agtggccatg gggaatgctc agatcgaagt aaaacatgct gcagactttg tgactcaatc
     8461 aaatgaagaa gatgggatat acgaaggact gaaacacttc ggtctgattt attagtcaat
     8521 gaaagaagga aaaaatcagt atggaagcag agacaccttt tcaaaaagta gaaacattcc
     8581 acaaaacttt tgatccaaga agaccagaga tacccacggc ttttacagaa aatgaagctc
     8641 atacacgtgc tgcgttcaaa atagaagaac ttgttgaatt tgttgcagct acttcaccta
     8701 ataaagaaca actgcatgaa gctgttatgc tgctgcacga agcattagat aaagcagaag
     8761 aaaaaatact tggtaaaaca cagtggggaa gtgatccgct ggttgaacaa gtagatgcac
     8821 tgacagatat cctttacttt acttatggtt ctttttcatt actaggaata gtgcctgatc
     8881 gaatattcga aatcgtccat caggcaaata tggggaaatt atttccagat ggaaaacctc
     8941 attatgaccc tgtaacaaat aaagtgttga aacctgaaaa ctggcagatg gaatatgctc
     9001 cagaacctaa aatcgcggca gaaatccaac gtcagattca agaagcgatt gctaagaaga
     9061 aatccgctga tataggcatg tgcacaaatg aaaaagagtg atcagagttt cactattttt
     9121 gttatcttta tacgatggaa aaacaaaaga ttttcgttta agttagtgaa tgcatgaaaa
     9181 tagtatgcta taatctagaa tagatgtctt ttgcacgaga gacgtattat ttggatttat
     9241 gccaagcaga acgccatctg ttgcataaaa gatgcatact gaaaacggag gaaccataaa
     9301 tgggaaataa tgttatcatc ggaatcgtca ttgcaatcat tatagtcgcc attgtcgtct
     9361 ttttggttag ttacttgatg aagaaaaaaa accaagatcg attggatgcc ttagaaaaac
     9421 gcaaggaaga attatttgac ttgccagtga ttgaagaagt cgatgatgtt aaaaaaatgc
     9481 atctggttgg gcaaagccaa aatacctttc gtgaatggag tcaaaaatgg aatgacatat
     9541 ctacttcctc gttcgctgaa ctagaaagtc aaattttcga agtggaaaac ctcaatgaaa
     9601 gttttcggtt cttaaaagga aaaaaagcag ttgttgaagc agaagctaca atggaccaaa
     9661 tggagaaaca agtgacggaa atccgtgaag gtctaaagga attgcgggaa acggaagaac
     9721 gcaactcact agctgttcag caggcacttg acgtctatga agaactgaaa gaaaaagtca
     9781 gagaagacga gcatgaatac ggaccagctc tttttgaatt gcaaaaacag atcaaagtga
     9841 tcgaaaaaga atttacgcag tttgtgactt taaacacttc tggagaccct gttgaagccc
     9901 gcgaggtttt ggataaagca gaaaaacata cgtatgaagt ggaagctctg atgaaaaaaa
     9961 ttccaccgct gtatgaggag ctccatacca ctttccctga acaacttgaa gaaatcagtg
    10021 atacttacga gaaattgatg gaagaacaat atgtattccc agaagaagat cttgctgaag
    10081 atatcgcaaa agtaagtcga agaattgaaa attcattagc caatcttgaa aaaacagaag
    10141 ttgaaacggt cgaatttgaa aaccgtgaaa cagctgattt gattgattcg ttatatgata
    10201 tcttagaacg ggaaatggaa gctcagagat atgtaaaaac taaccaatca acgattgcag
    10261 agtatatcaa acatacaaca aagaataacc gtcaattatt gattgagctg gatcacacat
    10321 ctcaaagcta tacattgaac cacaatgaaa ttggccgtgt acgaggtttc caaaccgaag
    10381 tggaagaaat ggaacgtcaa aatgaacaga tgattccaca gatccgtcaa cacgaaattc
    10441 cttattcaga agtgcgcacg ttctataaaa cagtcttcaa agtcttagaa gatatcgaaa
    10501 agcaacaagt agagatcgac gactcattac atgaattgag aaaaggcgaa aaagaagcgc
    10561 aagaaaagat cgatacattc gaattcaaat tgcgcagttt gaaacgtttt gtagaaaaac
    10621 aacgtttgcc tggcttgccg aatgattacc tagaattctt ttttgttgct actgaccgta
    10681 ttgaagaact aagtgttgtc ttgaataaaa ttcgagtaaa catggaagag gtcaatcgtt
    10741 tagttgctct atgtgaagaa gatctagaat tattagataa gaagacacat gatttagtag
    10801 atgcagcagc attaacggag caaatgctcc aatatgcaaa tcgttatcgt catacacacg
    10861 aagaagtgag agaagcaatt gataaaagct actatttatt caataaagaa tatcactatc
    10921 aagaagcatt agacgaaatc ggtacagcat tagagcgagt agaacctggt gctttcaaac
    10981 gcatcgaaga tttttatttt aatcatccag acttagtata aagcaaaaaa gttagtaaac
    11041 cagcaagagc aagacggatt attgtcttgt tcttgtcttt ttttgtatat ttgaaaattg
    11101 aaacaagtga aaatttcacc tgctcttgaa agcaccttgg acaaccgtta taatagaaaa
    11161 gaatttcaaa aaagaggggt ttcttatgat atattttgat aacagtgcaa caaccccaat
    11221 ctttccgcaa agcttagatg catatgtaaa aaccagtcag cggattattg ggaatccatc
    11281 aagcttgcat gatttaggca atcaagctaa ccggttgttg cagcaagcaa gaaagcagat
    11341 cgctgatttg atccatgtag aaccagaaga aatctatttt acttcaggcg gaacagaagg
    11401 agataactgg gtattaaaag gaacgatgat cgaaaaaaga gaatatggga atcatatgat
    11461 catttcagga gtcgaacatc cggccgtcag cgagacagca gaacaattaa aagaattagg
    11521 aatcgaagta agtatcgccc cagtggataa acgcggattt gtacgtgtcg acgaattgaa
    11581 agaattaata agaaaagaga cagtattagt ctctgttatg gctgtgaata atgaagtagg
    11641 atcgattcag cccatccagg aaatcagtga tcttttggat gattttccta aaattcattt
    11701 ccatgtagat gctgttcagg cgattggaaa agtaccattc tcgcaatggt tgacagaaag
    11761 agttgatttt gcaacatttt cagctcataa attccatggc ccacggggaa ctggtttcat
    11821 ttattggaaa aagggtcgtc gtttagcacc attactgaca ggtggagggc aagaaagaaa
    11881 tcagcgaagt gggacagaaa atgttccagg tattgtggct atggttaaag ctttacgttt
    11941 atcattagag ataaaggaac aaaaacctga gcagacacaa cgcttaaaag tagctctaat
    12001 caatgcgttg aagacgtatg agaaagtgac gattttttca gaaggaactg actatgcacc
    12061 gcatatttta tgttttgctc taaaaggaat tcgcggcgaa gttctcgtcc atgccttaga
    12121 agaaaaacaa atatttgttt ctactactag tgcctgctcc tcacgtaaac atatggcaag
    12181 cagtacattg cacgcaatgc atgtaccaaa tgatctggct acatctgctg ttcgaatcag
    12241 cttagatgaa aacaattcgc ttgcagaagt cgagcaattt atgattattt tcaagcagct
    12301 ttataagaaa ttttctgcaa tcaattaaaa gaggagtgtt cttgtgaaat acagtgaaat
    12361 tatggtccgt tatggggaac tttcgacaaa aggaaagaat cgaaaaagct ttatcatgca
    12421 actagcacaa aatgtcagac aagctttgaa agactttcca gaaatcaaaa tccatgctga
    12481 tcgggaccgg atgcatcttt tattgaatgg cgcagacggg cagctagtta ttccaaaact
    12541 agcaaaaata tttgggatcc aaaatttctc tccaagtatt cgtgtagaaa aagatgtcga
    12601 agttttgaaa caagctgttc aagacatcat gaaagaaatt tatactggga aagaaacatt
    12661 taaaattatc gctaaaagaa gcgatcacca atttgaattg acaagtaatg aattgaatca
    12721 aacattaggt aatgctgttt ttgatatttt cccgcatatc caagttcaaa tgcgtcaacc
    12781 agatattcca ttacgtgtag agattcggcg tgatggcgct tatctatcgt atgaaacgat
    12841 caagggagct ggaggattgc ccgtaggaac aagcggaaaa ggaatgctta tgctttctgg
    12901 ggggattgat tctcctgtag cagggtactt tgccatgaag cggggagtgg aaattgaagc
    12961 tgttcatttt gctagtccgc cgtatacaag tgaacaagca ctgcaaaaag caaaagatct
    13021 aacagccaaa ctagcacctt atgtgggaac gatccatttt atcgaagtgc catttaccga
    13081 gattcaagaa gaaatcaaaa agtcagtgcc acaaggatat tggatgacaa ttactcgtcg
    13141 aatgatgttg cgtttgaccg atgaaattcg ccgtattcgt catggtttag tcattttgaa
    13201 tggtgaatca ttaggtcaag tggcttcaca aactttgcaa agtatggtgg ctatcaatga
    13261 agtaacgaat acgccaatca ttcggcctgt agcgacaatg gataaacttg aaatcattga
    13321 agtagcagaa cagatcgata catttaatct ttctatccag ccttttgaag attgctgtac
    13381 gatttttgct cctccacagc caaaaacacg ccctcaactg gaaaaggtcc atcaatatga
    13441 agagcgttta gcaatagatg aaatgatcca acgagcacta gctggcttga agatggaaga
    13501 gatacaagca gaatcgtcta atgaaaaaac tgaagaattt tcagaattgc tataagaggt
    13561 tatgaaaata gtgttttgac cagagtatta gagaaacaaa acgaaaaaat agctccatgt
    13621 attttaccgt ttttgaacta atgtcgaaga ttagctgatt gaataccatt tatcaagaag
    13681 ttatggaaaa gccggttctt ttttactaac tgaaaaataa aattttattt agagatcaag
    13741 ctacagttga taaatgatat aaaaaagaga atttcccatg aaatagcgag gttgtgacag
    13801 aagtgggcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttttca aatttttgtg
    13861 aaatttcggc ttatttttcg aagaagttac ttctggaaca ccgtgtatca gaggttgcga
    13921 aaaagctgcc ctgca
//
LOCUS       DADLIO010000068        13834 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.071, whole genome shotgun sequence.
ACCESSION   DADLIO010000068 DADLIO010000000
VERSION     DADLIO010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13834
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.071"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(143..1345)
                     /locus_tag="JOX41_002233"
     CDS             complement(143..1345)
                     /locus_tag="JOX41_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAY6449947.1"
                     /translation="MKTKYPCVYQDKNGRFSYLVELGTDQVTGKRIQKKGTKDSLGKR
                     FSSAREAHKEVMRIKNEYMVVNGFANYDLTYKEFMEQSYVPHYKASVQKSTWSSRECG
                     LIQITEFFGDKKLREINVRDCENYRIWLLNDSGYSQAYSSLMYGMFRKSLDYAVTLQF
                     LNENISKRTKAIPKGKSIVPYWTKEEFEEVLAKIYKDDFYEHMCFLMIWLYYMTGVRV
                     SEGLALNWNDVDFKRKKLRVHHTLEMTNQKDFIRKPYTKTESGLRIISLDDDTIEVLK
                     KWKVIQKNHGVEQFILSYTDLPLYRSTVQRIIQRYAKLAKVPLIQGKGLRHSHVSYLI
                     NEFNADILVVSQRLGHSSPEITLKHYAHLWSRNDEGIAEQMTGNIKFTCATKSKVANF
                     NGNQAVKI"
     gene            complement(1348..1542)
                     /locus_tag="JOX41_002234"
     CDS             complement(1348..1542)
                     /locus_tag="JOX41_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAY6449948.1"
                     /translation="MKNTICRKDLEALGFKTHQATTIIRQAKTRMVNQGYPYYNNKRV
                     GVVPRQVIEEIIGVPLSQEE"
     gene            complement(1589..2437)
                     /locus_tag="JOX41_002235"
     CDS             complement(1589..2437)
                     /locus_tag="JOX41_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HAY6449949.1"
                     /translation="MQAYNQKIIETPTYIEIYDYEAIITPKRKTIENEVNLERKQKLA
                     WIYENDITLEKRKNYDELSAQGQYDSLKRKQKHYQSMRFEIARLVDTNFDNQTKFLTL
                     TFKENIQDIEYANNEFKKFIKRLNYDLYKTKKANLKYLATWEKQQRGAIHYHIILFDF
                     PFISFNRLTTIWGQGFVKINKIDVDSIENRGRYISKYFDKELELKEHKKKAFFKSRNL
                     KLPTVTKKMVKKPYDSTNQDILYTSEYIVRRPFFYNALALNELGSPEQVMDFQESTVH
                     YTKIKK"
     gene            complement(2642..2992)
                     /locus_tag="JOX41_002236"
     CDS             complement(2642..2992)
                     /locus_tag="JOX41_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449950.1"
                     /translation="MPIKITDLSLPKETLEKEYQVVNVTRWQKEGEILGWSYECILPK
                     LRYEKISVKVKSEHPVITPEELTQQGLAIITFTNLVIVPWGRSNGQFVSYGLSATADT
                     ATLIPRKQGTTTQN"
     gene            3587..4033
                     /locus_tag="JOX41_002237"
     CDS             3587..4033
                     /locus_tag="JOX41_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HAY6449951.1"
                     /translation="MKDYVVQITKEVLEESKTLNKLSSKAKEEAVTILSSGIIDYIEM
                     SGEIKYGEKDRIAKMVKESIKTFDVKQDLTFNDSYLIGKLINILGTDEDTELFLSSLS
                     MIFTDKHFSTRFGGEELVEIFQSMRPALIKLYREKTPDEFYDWFEK"
     gene            4657..5649
                     /locus_tag="JOX41_002238"
     CDS             4657..5649
                     /locus_tag="JOX41_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAY6449952.1"
                     /translation="MYWEEIELEKTLGPGGEIRAVQRDKKNISKWEKLKKQLRRDKWM
                     YLLLLPGIIMTFIFKYVPMYGAVIAFKDYNPMLGILESPWVGLDHFREFISSPNFTLL
                     LSNTLKISIYGLLLGFFPPIILALSLNQIINKKIKQKIQLILYAPNFISVVIIVGMLF
                     LFLSANGPINGLVEKVTGQPIMFMSNPAYFRTIYILSGIWQGIGWSSILYTATLAGVS
                     TDLYEAANIDGANILQKIWHIDLPALRPVMVISFILAAGGIMNVGYEKAYLMQTSMNI
                     PASEIISTYVYKVGLQSGDYAYSAAVGLFNMIINVVLLLIVNNITKRLNDGQGL"
     gene            5665..6549
                     /locus_tag="JOX41_002239"
     CDS             5665..6549
                     /locus_tag="JOX41_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAY6449953.1"
                     /translation="MNSALSKIDRQILWLNRVIVTFLVVITIVPLIYVLVASFMDPAT
                     LINKGISFNPKDWTIQGYQRVFADDSILRGFVNSLFYSFSFSLLTVFITMITAYPLSR
                     PNLAGKKIIMTFFVITMFVGGGLIPTYLLVKNLGMLDSVWAIIVPGAINVWNIILART
                     YFSALPKELSEAATIDGANDLQILFKVMLPLAKPIMFVLFLYAFVGQWNSYFDAMIYI
                     KDPDLQPLQLVLRNILIQNQPSQDMVGANTAMAEMKQIAELIKYATIVISSLPLIIMY
                     PFFQKYFDKGVLVGSVKG"
     gene            6598..8205
                     /locus_tag="JOX41_002240"
     CDS             6598..8205
                     /locus_tag="JOX41_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAY6449954.1"
                     /translation="MKAKWMLPIVFTSVLILGACGGSKEKSKSSPDYELENVSFPLKE
                     KVSLKMMSQSAPLAPNDPNDKLIFQRLEEETNLHIDWTNYSSDFAEKRNLDIASGDLP
                     DAIFNAAAGDYDLLNWAESGVIVPIEDLIEDYMPNLKKIFDENPEYRQMSTAPDGHIY
                     SMPWIEELGEGKESIHTVNGMAWINKEWLDNLGLEMPQTTDQLMTVLEAFKTQDPNGN
                     GEADEIPFSFINNGGNEDLKFLMGAFGLGDNDDHLVVDNDGQVQFTANKEGYKEAIKY
                     FNEMNNKGLIDKEAFEQDWNTYVAKGKEHKYGVYFTWDKANITGADDSYDVLPVLAGP
                     DGTKHVTRTNGMGFSRDRFVITSANKNLELTARWIDKMYEPLQSVQNNWGTYGDEAQA
                     NIFELKDGMLKHLPLEGTAPGELRQKTEAGGPLAVLDSYYGTVTTMPDDAKWRLDLMH
                     DTYLPYITEDNIYPRVFLEKEETDRLAKIETDMWDYIYRKRAEWITGGKIDEEWEEYL
                     AELERVGLEEWIQIKQTGYDNFLKGAQ"
     gene            8206..9690
                     /locus_tag="JOX41_002241"
     CDS             8206..9690
                     /locus_tag="JOX41_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016621147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HAY6449955.1"
                     /translation="MLVEETAILDKANRFIEMMRGKVNPQYRQNYHFSAPIGWINDPN
                     GFIYYKGHYHLFYQYYPYDSRWGPMHWGHARSSDLVHWEDLPVALAPDQPYDSGGCFS
                     GSAIERDGKLYLFYTGCQEIDGISHQHQCLAVSEDGIHFSKYSGNPVVAEKQLGENGL
                     IQEFRDPKVIVHNDGYYMVVATKSTQSTGRIVMFQSSDLYTWHFYSVLLEGTSEQGIM
                     WECPDLFHLDGRDVLIMSPIQIKKNGLEYHNISSTMACIGEVNWETGQMIVDNFHEMD
                     FGMDFYAPQTTRDPNGGRVMIAWMQMWDRTLPTHELGHLWAGSMSLPRELRVKKNRLV
                     QKPISTVYSHLVYQQGSENIAVTDTSVVFRNALSDSSYLHLVADLEKAEVFTIELLRS
                     KTDCLKLAYDTATQVFELDRQKLGRELTGAEEDPLNVRKVEVPLIDNQLVLEIFRDTS
                     SIEVFINGLEVMTATFYELEKARDILFHSIGESRIQAFETASVK"
     gene            9867..10859
                     /locus_tag="JOX41_002242"
     CDS             9867..10859
                     /locus_tag="JOX41_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005230454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAY6449956.1"
                     /translation="MKATMKDVAKLAGVGVGTVSRVLNNGSVKASTREKVEAAMTELN
                     YQPDFYARGLKMKHTNTVALILPTVWHPFFGEFAYHVETALERQNYKLYLCNSSGNSE
                     KEQEYIQMVSQNKVDGIIGITYSDIDEYISSNLPFVSIDRYFTEEVIYVTADNAAGGR
                     LAANELYRRGCQNVAYIGGYQETPNETKSRRKYFEIECRQLGISYKALDMLEPLDHLS
                     ERVTNFLLENPDIDGIFTINDPMALAVIDMLEKIGKNVPEDVQVIGFDGQKMTEGDPY
                     LVSTIAQPTKQMAEVAVAKLIAVINGETVEKRTVLPIEFGEGDTTKPLVRNDFA"
     gene            10911..11780
                     /locus_tag="JOX41_002243"
     CDS             10911..11780
                     /locus_tag="JOX41_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAY6449957.1"
                     /translation="MLYGGIEAGGTKFVCGIGNEQLQVIERKSFPTTTPEETMEQVFD
                     FFDKYKGNIASIGVGAFGPIDIQIESRTYGYITNTPKLAWQNYHFVGALENALSVPIY
                     WTTDVNAACYGEYMAGYGKGKNSVLYYTVGTGVGGGAVVDGKIVAGFSHPEMGHMLLQ
                     RHNEDQFEGICPFHHDCLEGLASGPAIEKRFGRKAQTISFDHPYWTIEADYLAQCVYN
                     TTLLYAPEVIILGGGVMKQPQLLELIRQSFKEKMGSYVDTPTLEEYLLTPRLADNAGL
                     IGCLALAIKKLNH"
     gene            complement(12200..13765)
                     /gene="guaA"
                     /locus_tag="JOX41_002244"
     CDS             complement(12200..13765)
                     /gene="guaA"
                     /locus_tag="JOX41_002244"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HAY6449958.1"
                     /translation="MSSPTRFDEEPKIIVLDYGSQYNQLITRRIREFGVFSELMSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDEKAFGIDEKIFDLGIPVLGICYGMQLITYKLGGK
                     VKPAKNREYGKAELEITSAEAALFQNTPEKQTVWMSHGDLVTQAPTDFDVVATSKDCP
                     IASIQNAERKMYGIQFHAEVRHSEYGNDLLRHFTLDVCQCTGDWTMDNFIDMEIAKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHVLLRKGEAEQVMESLGGK
                     FGLNIIKVDAKERFLSKLAGVSDPEEKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGELTEEKLEIVRESDAILREEIANAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
BASE COUNT         4239 a         2340 c         2855 g         4400 t
ORIGIN      
        1 ttgaaaaacg ttgatttatc ggcattcccc atccatatta tatttacgtc ttattcccac
       61 tcaatatgag tagcctcgta aagaagctat tatatcagtg ctttttcagc ctattcctca
      121 ttttggtagg gaaatggtag ggttagattt ttactgcttg atttccatta aagtttgcaa
      181 ctttagattt tgttgcacag gtaaatttaa tgtttcctgt catttgttct gcaattcctt
      241 catcattacg gctccataga tgagcgtagt gctttaaagt gatttcaggg ctagaatggc
      301 ctaaccgttg cgacacgacc agaatgtctg cgttaaactc attgattagg tagctaacat
      361 gagaatgacg taatcctttt ccttgtatta ggggtacctt agctagtttg gcataacgct
      421 gaataattcg ttgaacagtt gaacgataga gtgggaggtc agtgtagcta agaataaatt
      481 gttctacacc atgatttttt tgaataactt tccacttttt tagcacttca attgtatcat
      541 cgtccagaga aatgatccgc aagccgcttt cagtttttgt gtaaggtttc cgaataaaat
      601 ctttttgatt tgtcatttcc aaggtgtgat gaaccctcaa ctttttacgt ttgaagtcca
      661 cgtcattcca attaagtgct aatccttcgc ttacacgaac accagtcatg taatatagcc
      721 agatcattaa aaaacacata tgttcgtaga aatcatcttt ataaattttt gccaaaactt
      781 cttcaaattc ttcttttgtc cagtaaggaa cgattgattt tccttttgga attgcttttg
      841 ttcttttgga aatattctca ttcagaaatt gcagggtgac cgcatagtct aatgatttac
      901 gaaacatacc gtacataagt gaactgtatg cttgtgagta tccgctatcg ttcaataacc
      961 aaattcgata attttcacaa tctcgcacat tgatttcacg aagcttctta tcaccgaaaa
     1021 attcagtaat ctgaatcaat ccacactcac gagaactcca agtacttttt tgtacgctag
     1081 ctttgtagtg tggaacgtaa gactgctcca taaattcttt gtaagttaaa tcataattcg
     1141 caaatccatt tacaaccatg tattcatttt ttatacgcat gacttctttg tgtgcttcac
     1201 gagctgatga gaatcgtttt cctagagaat cttttgttcc tttcttctgg atcctctttc
     1261 cagtcacttg atctgttcct aactcaacta gataagaaaa gcgaccattt ttatcttgat
     1321 acacacaagg gtattttgtt ttcatagtta ttcctcctgt gaaagaggaa cacctataat
     1381 ttcttcaatt acttgtcggg gtactacccc aactctttta ttattataat atggatatcc
     1441 ctgatttacc attcttgttt ttgcttgtcg gattattgtg gtagcttgat gtgttttaaa
     1501 tcctagagcc tctaaatctt ttcgacaaat tgtatttttc attgtataaa ctcactttca
     1561 aagaaaacac tatcattggg taatagtgtt atttctttat ttttgtataa tgaacggtac
     1621 tttcttgaaa atccatcact tgttcaggac ttcccaactc atttaaagct aaagcattgt
     1681 aaaaaaatgg acgtctaact atatattcgc ttgtatatag tatatcttga ttcgtggaat
     1741 catagggttt ctttaccatc tttttggtga cagttggtag tttgagattc cgggacttga
     1801 aaaaagcttt tttcttatgc tctttcaatt ccagctcttt atcgaaatat ttgctgatat
     1861 agcgcccgcg attttcgata ctgtctacat cgatcttgtt gatcttaacg aaaccctgac
     1921 cccaaatcgt agttaaccgg ttaaatgaga taaaggggaa atcaaacaag ataatatggt
     1981 agtggattgc accgcgttgc tgcttttccc acgtggcgag atactttaaa tttgcttttt
     2041 tagttttata gaggtcataa ttcagtcgtt tgataaattt tttaaattca ttatttgcat
     2101 actcaatgtc ttgaatgttt tctttgaaag tgagagttaa aaatttcgtt tgattgtcaa
     2161 aattcgtgtc tacaaggcgg gcaatctcaa atcgcatact ttgataatgt ttctgtttgc
     2221 gttttaaact gtcatattgt ccttgagcgg ataattcatc atagtttttt cttttttcaa
     2281 gagtaatatc attttcataa atccaagcta atttttgttt tcgttccaga tttacttcgt
     2341 tttcgatcgt tttacgtttg ggagtaatga ttgcttcata atcataaatt tcaatatacg
     2401 tgggagtttc aatgattttc tgattataag cttgcaaaaa tcatcactcc ttgttgcgta
     2461 ttcgattgtc aaagaaccag tcattttctc ctgatgttga tctataaatc aagttaaggg
     2521 ggaaggcctg cgtagcagcc cttctagcct atggggtgtt gggcggtctt aacggacaga
     2581 aacggctctg tgggcgctgc cccgccgttt cgtcctaacc acccaacact ccatagtata
     2641 gttagttttg tgtagtggta ccttgttttc tgggaatcaa agttgccgta tcagcggttg
     2701 ccgataaccc ataactgaca aattgtccat tcgagcgtcc ccaaggtaca atcaccaaat
     2761 tggtaaatgt aattatggct aaaccttgtt gggtaagttc ttccggcgtg atcacaggat
     2821 gttcagattt gactttgaca ctgatttttt cgtagcgaag ttttggtagg atacattcgt
     2881 agctccaacc tagaatttcg ccctcctttt gccagcgagt gacattgacg acttggtatt
     2941 ctttttcgag tgtttctttt ggtaaactga gatcggtaat ttttattggc atcacaattc
     3001 tcctttttta tacgaaagtt tatacgattt gattaaaaaa tatagatggc catctacgac
     3061 ttgtattata tacgagaact tatacgtagt caagagattt tctaaaaaaa tatatacgat
     3121 tttttatacg agtgttataa tgaaaaaaat gataaggagg aatttgaata tgtttggttt
     3181 agtacaacct aataaagtga aggtgggcca acgaatcaaa gaaataaaag acggaatgtc
     3241 tctctctttt acagaattag ggaatcgatt aggtttaaaa aagccgacga tcagttccta
     3301 cgttcaaggc tatgcgttgg ctcctaagag tgtgatcaac caattatcta gtatcagcgg
     3361 aaaacctgtc ggctggtttt attttgggca tgtggaagaa tatatccgag agtatttgtt
     3421 tctcattggt cagaaaaaaa tagtggacga ttatcctgaa atcattgaga aaataaagca
     3481 agaattttat acgggcgagt tcaaaaatcc tgcttgggag aatgagctag gctatccttt
     3541 ggaggaattt atccaagaat gttttgtaga atattcgagt gaaatcatga aggactatgt
     3601 cgtacagatt acgaaagagg tacttgaaga atccaaaacg ctaaacaaac tatcatcaaa
     3661 agcaaaagaa gaagctgtca cgattctttc atctgggatc attgactata tcgagatgag
     3721 tggtgagatc aagtatggag agaaagatcg cattgcgaaa atggtgaaag aatcaataaa
     3781 aacctttgat gtgaaacaag acctgacatt taatgattcc tatttgattg gaaagttgat
     3841 caatattctt ggtacagatg aagatacgga gctgtttctt tcttctttat caatgatatt
     3901 tactgataag catttttcca ctcgatttgg tggggaagaa ttagtcgaaa tatttcaatc
     3961 gatgcgacca gcgttaatca aactctatcg ggagaaaaca ccagatgaat tttatgattg
     4021 gtttgagaag taaaataaga aaagtggctt agattacaag ttggtgaaaa aatttttttc
     4081 agcataacat cagtaatcta taaaggggtt gttgattata ctgtagaagt taagtactca
     4141 agagattttt tgtacgtaaa caaagcaaaa aagggtgcag tttcactaga aaatgtactc
     4201 ttttttgtga tttttcttag ttatagagtt tttttgaaac tttaaaaatg agaaaacata
     4261 ttgattttaa agagtgtaga catagcttct tttgctaaat agattaaact tactggtgag
     4321 tggtcttgaa catactttta aatcacattt tactgagttt tattggattt tataattcat
     4381 tggaaacctc gtacttaatc tgtttttatc tatcgactag aatctgtata tattccagct
     4441 atcaatgagg ccgcagaaaa gggtgcttaa aaataatctg ttgtttaaaa tattattatc
     4501 agaatactta gatacaaaat tctggcacaa agtaaaaaaa atattgactt aaaaaaatgg
     4561 atatggtaat ctataaacga aaatagtggt aacgtttcca aaatgcatct tcgttaaatt
     4621 tttatttttt taaacgaaaa tggaaacgtt tctaaaatgt attgggagga gattgaattg
     4681 gaaaagacat tgggaccagg tggtgagata agggcggtac aacgggataa aaaaaatatt
     4741 tcgaagtggg aaaaattaaa gaaacagttg cggcgtgata agtggatgta cttgttgctc
     4801 ttaccaggta tcatcatgac gtttatcttt aagtatgtgc caatgtacgg tgctgtgatt
     4861 gcatttaaag actataatcc tatgctagga attttggaaa gtccttgggt aggactagat
     4921 cactttaggg aatttatcag ttcaccaaat tttacgcttt tgctgagcaa cacattaaaa
     4981 attagtattt atggtttatt gttaggtttt tttccaccaa ttattttagc actgagcttg
     5041 aatcaaatta tcaataaaaa aataaaacag aaaatccagt tgattctata tgcgccgaat
     5101 tttatctcag tagttattat tgtggggatg ctgtttttgt tcctatccgc aaatggacct
     5161 attaatgggt tagtagaaaa ggttacgggg caaccaatta tgttcatgtc taatccagct
     5221 tatttcagaa cgatttatat tttatcggga atttggcaag gaatcggctg gtcatccatt
     5281 ctttacaccg caacgctggc gggagtcagt accgatttat atgaggcagc aaatatcgat
     5341 ggggcaaata ttttacaaaa gatttggcat atcgatttgc ctgcattgag gcctgtgatg
     5401 gtgatcagct tcatcttggc cgccggcggt attatgaatg taggatatga aaaagcctac
     5461 ttgatgcaaa cttcaatgaa catccctgcc tcagaaatca tttccactta tgtatacaaa
     5521 gtcggcttgc aatcaggtga ttatgcctac tctgctgctg ttggtctgtt caatatgatt
     5581 attaatgtcg ttttattact gattgtcaac aatataacca agcggctaaa cgatggtcaa
     5641 ggcttgtaat gaaaggagaa aattatgaat agtgctttat caaaaatcga ccgtcaaatc
     5701 ttatggttga atcgagtgat tgtaactttt ttagtcgtca tcaccattgt tccgctgatt
     5761 tatgtactgg tagcttcttt tatggaccca gctactttga tcaataaagg tataagcttc
     5821 aatccgaaag attggacaat acagggatat caacgggtat ttgcagatga ttccatttta
     5881 cgcggttttg taaattcgtt gttttactct tttagcttca gcttattgac tgtatttatt
     5941 acgatgatca ctgcgtatcc tttgtctcga cctaacttgg cggggaaaaa gattattatg
     6001 actttttttg tcattacaat gttcgtgggt ggtggcttga tacctaccta tttattggta
     6061 aagaacttgg gcatgttaga tagtgtatgg gcgattatcg taccaggtgc tataaatgtg
     6121 tggaatatta tcttagcccg tacctatttt agtgctttgc caaaagaact ttctgaagct
     6181 gctactatcg atggcgccaa tgacttgcaa atactgttca aagtcatgct tccattagcg
     6241 aaaccaatta tgttcgtatt gtttttatat gcctttgttg ggcaatggaa ctcatacttt
     6301 gatgccatga tttacatcaa agatcccgac ttacagccgt tgcaactcgt attaagaaat
     6361 attttgatcc aaaaccaacc ttcacaagac atggtgggag ccaatactgc catggcagaa
     6421 atgaaacaaa ttgctgagtt gatcaaatac gcaacgatcg tcatttctag tctgccatta
     6481 atcataatgt atcctttctt ccaaaaatat tttgataaag gtgttttagt tggttctgtt
     6541 aaagggtaag tattgttcac tatttgtatg aataaaaatt ataaaggaga ttttaagatg
     6601 aaagcaaaat ggatgctgcc aatcgttttt acttccgtac taattttggg ggcttgtgga
     6661 ggctcaaaag aaaagagtaa atcaagccct gattatgaac tagaaaatgt ctcttttcca
     6721 ttgaaagaaa aagtatcttt aaaaatgatg tctcaaagtg cccctttggc tcccaatgat
     6781 cctaatgaca aattgatttt ccaacgatta gaagaagaga ccaatctcca tattgattgg
     6841 acaaactaca gtagtgattt tgccgaaaaa agaaatttgg atatcgctag tggtgattta
     6901 ccagatgcca tcttcaacgc cgctgcaggt gactatgatt tattaaactg ggcggaaagt
     6961 ggcgttattg taccgattga agatttgatc gaagattata tgccaaatct gaagaaaatt
     7021 tttgatgaaa accccgaata ccgacaaatg tctactgcac ctgatggtca catttactct
     7081 atgccttgga ttgaagaatt aggcgaagga aaagagtcga ttcatacagt aaatgggatg
     7141 gcttggatca acaaggagtg gttggataat ttgggtcttg aaatgccgca aaccactgat
     7201 cagttgatga ctgtgttgga ggctttcaag acgcaagatc caaatggtaa tggtgaagca
     7261 gatgaaattc cttttagctt tattaacaat ggaggaaacg aagacttaaa atttttaatg
     7321 ggggcattcg gtctaggtga taatgatgac cacttagtcg ttgataacga tggtcaggta
     7381 caatttactg ctaacaaaga agggtataaa gaagccatca aatatttcaa tgaaatgaat
     7441 aataaaggtc ttattgataa agaggctttc gaacaagatt ggaatacgta tgttgccaaa
     7501 gggaaagaac ataagtatgg cgtgtacttt acttgggata aagcaaatat cacgggtgca
     7561 gatgatagtt atgacgtctt gccagtctta gcgggaccag atggaacgaa acatgttact
     7621 cgtacgaatg gcatgggttt ctcaagagat cgtttcgtaa ttactagtgc gaataaaaac
     7681 ttggaactta cagctaggtg gatagataaa atgtatgaac cgttacagtc tgtccaaaat
     7741 aactggggaa cctacggtga tgaagcacag gcgaatattt ttgaattaaa ggatggtatg
     7801 ttaaaacatt tgcctttaga ggggacagca ccgggggaac taagacaaaa aaccgaagct
     7861 ggaggaccat tagcagttct tgattcttat tacggcacag tcactactat gccagatgat
     7921 gcgaagtggc gtttagattt gatgcatgac acgtatttgc catatattac agaagacaat
     7981 atctatccac gtgtcttttt agaaaaagaa gaaacagatc gattagcaaa aatcgaaacg
     8041 gatatgtggg attacatcta tcgcaaaaga gcagagtgga tcaccggcgg taaaatcgat
     8101 gaagaatggg aagaatacct tgctgaattg gaacgtgtag gtttggaaga atggattcaa
     8161 ataaaacaaa ctggctatga taattttttg aagggagcac aataagtgtt agtagaagaa
     8221 acggcgattt tggataaagc aaatcgattt attgaaatga tgcgaggaaa agttaaccct
     8281 cagtatcgac aaaactatca tttttccgca cccatcgggt ggataaatga ccccaatggg
     8341 tttatatatt acaaagggca ttaccatctc ttctatcaat actatcctta cgatagtcga
     8401 tgggggccca tgcattgggg gcatgcgcgc agtagtgatt tggtccattg ggaagatcta
     8461 ccagtagcgt tagccccaga tcaaccttat gacagcggcg ggtgtttctc aggaagtgca
     8521 attgaaagag acggaaaact atatttattt tatacaggct gtcaagaaat tgatggtatt
     8581 agccatcagc atcaatgttt ggcggtctct gaagatggta ttcattttag caaatacagt
     8641 ggtaatcctg tggtagcaga aaaacagcta ggtgaaaatg ggctaataca agaatttcgt
     8701 gatcctaaag taattgttca caacgatggt tactatatgg tagtagctac taaatctaca
     8761 cagtctactg gtagaatagt gatgtttcaa tcgtcagatt tgtatacttg gcacttttac
     8821 tctgtgctgc tagaagggac ttcagagcaa ggaataatgt gggaatgtcc tgatttattc
     8881 catttagacg gacgagatgt cttaatcatg tctccgatac aaatcaagaa gaacggactg
     8941 gaatatcata atatcagttc taccatggct tgtattggtg aggtaaactg ggaaacaggt
     9001 cagatgatag ttgataattt ccatgaaatg gattttggaa tggattttta tgcaccacaa
     9061 acaacaagag atcctaatgg tggacgggtg atgattgctt ggatgcagat gtgggatcgt
     9121 acattgccta cacatgagtt aggccatctt tgggcaggct ctatgagttt gccccgagag
     9181 ttaagagtga aaaaaaatcg attggtacaa aaacccatct caactgtata tagtcattta
     9241 gtttatcaac aaggcagtga aaatattgca gtgactgaca catcagtcgt atttcgaaac
     9301 gcgctgtctg attcttcata tttacatcta gtcgcagatt tggagaaagc tgaagttttt
     9361 acaattgaat tactgcggtc taagacggat tgtctcaaac tagcctatga cactgctaca
     9421 caggtttttg aattggatcg tcagaaacta ggaagagagc ttacaggggc ggaagaagac
     9481 cctctgaatg tacgaaaagt tgaagtacct ttgattgata atcagctcgt tcttgagatt
     9541 tttagagata cctcatcaat tgaagtcttt attaatgggt tagaagttat gacggctact
     9601 ttctatgagc tggaaaaagc tcgagatatc ttgtttcatt cgatcggaga aagtcgtatt
     9661 caagcttttg aaacagcgag tgtgaaataa atgtttgatt gcttaggcga tgaatcaatt
     9721 atttaatagg ttttgaagga taatgttttt agaaaagaac agatagctag atttcccatg
     9781 gatttgctat tagtattttg aaaaaattag taatttatga caaaattcat tatactaaac
     9841 ttgtgcagaa atgtgaggga tcaactatga aagcaacaat gaaagatgtc gcaaaattag
     9901 caggtgttgg agtaggaact gtttcccggg tattgaataa cggttctgtt aaagcttcta
     9961 ctagagaaaa agttgaagca gcaatgacag agttaaacta tcaaccagat ttttatgccc
    10021 gggggttaaa gatgaagcat acgaacacgg ttgctttgat tctacccacg gtatggcatc
    10081 cattttttgg cgaatttgcc taccatgtag aaacagcatt agaaagacaa aactacaagc
    10141 tttatttgtg taactccagt ggtaatagtg aaaaagaaca agaatatatc cagatggtca
    10201 gccaaaataa agtagacggc atcattggaa ttacttattc agatatcgat gaatacattt
    10261 cgagtaatct gccttttgtt agtattgacc gttatttcac tgaagaggtg atttatgtga
    10321 ccgctgacaa tgcggccggt ggacgtttgg ctgcaaatga actttatcgc cgaggatgtc
    10381 agaatgtagc atatatcggt gggtaccaag aaacaccgaa tgaaacgaag agtcgtcgaa
    10441 aatattttga aatcgagtgc cgtcaactgg ggatttccta taaagcgtta gatatgttag
    10501 aacctttaga ccatctctca gaacgtgtaa caaatttttt gttagagaat cccgatatcg
    10561 atgggatttt tacgatcaac gatccaatgg cattagctgt cattgatatg cttgaaaaaa
    10621 tagggaaaaa cgtaccagag gatgtccaag ttatcggatt tgatggtcaa aagatgacag
    10681 aaggagatcc ttatctagtc tcaacgattg cccaacctac aaagcaaatg gcggaagtgg
    10741 cagtggcaaa attaattgct gtcattaatg gagagacagt agaaaaacgt accgtattgc
    10801 cgattgaatt tggcgaaggt gacacaacga aacctttagt gagaaacgat tttgcttagt
    10861 gcaaatacgt ttcttttttt gaaaatgagt gaatgaaagg tgtagataaa atgttatatg
    10921 gtggaataga agccggtgga acaaagtttg tctgtgggat tggtaatgaa caattacaag
    10981 tgatagaacg gaaaagtttt cctaccacaa caccagaaga aacgatggag caagtgtttg
    11041 atttctttga taagtacaaa ggaaatatcg catcaattgg tgtaggagca tttgggccta
    11101 ttgatattca aatcgaatca agaacttacg gatatatcac caacacaccg aagttagctt
    11161 ggcaaaatta tcattttgta ggagctttgg aaaacgcctt gtcggttccc atctattgga
    11221 ctaccgatgt aaatgctgct tgttatggag aatatatggc agggtatgga aaaggtaaaa
    11281 atagtgttct gtattacacc gttggtacag gtgttggtgg tggtgctgta gtggatggga
    11341 aaatagtcgc aggttttagt catcctgaaa tgggacatat gctcttacaa cgtcataatg
    11401 aagatcaatt tgaaggaatc tgtccttttc atcatgattg tttggaaggg ttagcatcag
    11461 gacctgcgat tgaaaaacgc tttggaagaa aagcccagac tatctcattt gatcatcctt
    11521 attggacgat tgaggcagat tatcttgctc agtgtgtgta taacacaacg ttactatatg
    11581 caccggaagt aataatttta ggcgggggtg taatgaaaca gccgcaacta ctcgagttga
    11641 ttcgccaatc gtttaaagaa aaaatgggtt cctacgtgga tacgcctact ctcgaagaat
    11701 atctactaac tccaaggctt gctgacaatg cgggcttgat tggctgccta gctttagcaa
    11761 taaagaaact caatcattag aatagtattt attagaacta ttcataacat accggaagtt
    11821 taaaagggta ttctgaaact taaatagtct caattcattc ttctttcttg agaatctgag
    11881 tagagacttt tattctgttt caaattaata taattacgaa atgatattga gtacaagaaa
    11941 gttcttttta ccagatcttt taaatcgaaa aatctgatat atatatttat agtactaaaa
    12001 atctgattag ataaaaagct aattcaatag gaaaataaag gtagtgaata aaagcaaagc
    12061 ccttgttagt agttaatcta acaagggctt tggtagggaa aatggtagga aaccatctta
    12121 ttttttacga aaatcaggaa ctttagtaat tgaataatgt tgatttatag gtattcctca
    12181 tccatattat gttggctctt tattcccact ccactgttgc aggtggtttg ctggtaatat
    12241 catacacgat acggttaacg tgtgcgactt catttacgat acggacactg attttttgca
    12301 agacttccca agggatacgg gcaaagtcag cggtcatgcc gtcaatagaa gtgacagcac
    12361 ggatacctac agtgtagtca tacgtacggc catctcccat aaccccaaca gagcgaatgc
    12421 ctggtaggac ggtgaagtat tgccagatgt cgcgatctaa accggcattg gcgatttctt
    12481 cgcgcaagat agcgtctgat tcacggacga tttctaattt ttcttctgtc aattcaccaa
    12541 ggacacgaat acctaagcct ggtccaggga atggttggcg ccaaacgatg ctgtcaggca
    12601 tgcctaattg ggtacctaat tcacgtactt cgtctttgaa caatgtgttc aatggctcga
    12661 tcagcttgaa ttgcatgtct tcaggtaatc cacctacatt gtgatgtgat ttgatggttt
    12721 gggcagtttc agttcctgat tcgatcacat cggtataaag ggttccttgt gcaaggaaag
    12781 aaacgccttc ttcaccggca agtttggttg cttcatcatc gaagacatat acaaattcat
    12841 ttccaatgat tttacgtttt tcttctggat cagacacgcc agcaagtttt gataagaaac
    12901 gttctttggc atcgactttt ataatgttca agccaaattt tccgccaaga ctttccataa
    12961 cttgttctgc ttcaccttta cgcaacaata cgtgatcaac gaagatacat gttaattgat
    13021 cgccgatcgc tttttgtaaa agaacaccaa caacagagga atctactccg cctgaaaggc
    13081 ctaataaaac ttttttgtca ccgacttgtt cacgaatttt tgcgatctcc atgtcgatga
    13141 agttatccat tgtccagtca ccagtacatt ggcagacatc tagtgtaaaa tggcgcaaca
    13201 agtcatttcc atattcggaa tggcgaactt ctgcatggaa ttggattccg tacattttgc
    13261 gttctgcatt ttggatcgat gcgatggggc aatctttgct ggtagcaacg acatcgaaat
    13321 cagtcggtgc ttgggtaact aggtcaccat gactcatcca aacggtttgt ttttcaggag
    13381 tgttttggaa aagggccgct tctgcagaag tgatttccaa ttctgctttt ccgtattcac
    13441 ggtttttggc tggtttaact tttccgccta atttataagt aatcaactgc ataccgtaac
    13501 agattcctaa aactgggatc cccaaatcaa aaatcttttc atcaatacca aaggccttct
    13561 catcataaac actgtttggt ccgccagaaa ggatgattcc tttagggttc attgccttta
    13621 cttcttctgc ggtaatgcgg tggctcatca actctgagaa aacaccgaac tcacgaatac
    13681 ggcgagtgat cagttggtta tactgactac cgtaatcaag tacgataatt tttggctctt
    13741 cgtcaaatcg tgttggtgaa gacaaatttg aataaaactt agtccgatat gcggcgcgtt
    13801 ctgtgcgccg catatttttt tagttttcaa agat
//
LOCUS       DADLIO010000069        13613 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.072, whole genome shotgun sequence.
ACCESSION   DADLIO010000069 DADLIO010000000
VERSION     DADLIO010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13613
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.072"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(1..144)
                     /locus_tag="JOX41_002245"
                     /pseudo
     CDS             complement(1..144)
                     /locus_tag="JOX41_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(186..1312)
                     /locus_tag="JOX41_002246"
     CDS             complement(join(186..1084,1084..1312))
                     /locus_tag="JOX41_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAY6449959.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PDQSTGLTGKEVAELRKENARLNEELEILKKAGSHILSENLNSLVQFIEKWCKDYTVS
                     LLCRLLEIPRSVYYFYKNKPLTATEIRNNKLKKKISTIFFTNKQRYGATKIHQVLLKE
                     GISVSLKHVQKLMKQLNLRSIVVKKYRPQRSNKPIISKENLLNQDFSTETICEKWAAD
                     ITYIPTKKNGWCYLSSIMDLHTKKIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMIL
                     HTDLGSQYTAREVEQWLKTNKIRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDF
                     EEANRALFSYIEGFYNRNRIHSSIHYLTPQEFEELAKEKMA"
     gene            complement(1716..2498)
                     /locus_tag="JOX41_002247"
     CDS             complement(1716..2498)
                     /locus_tag="JOX41_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449960.1"
                     /translation="MENSSNSAEVNVSTSTSEVVKCSQETTSLPEELLGDWQINNKDA
                     GIEISDSKAVFRIGRSQVESKDYYVDVNNKMLLHVYFSFEYDSVKYIEVSIERTGYSE
                     FISKSVGILTMHTKDGQYISLGVKRVSGENNETEAVTEQTMDERIDSSKSNETEVDTG
                     KTIDERIDSFIETYTAIPPTWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNA
                     VTEQVGKDIPLRLLENGKKDYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(2563..3399)
                     /locus_tag="JOX41_002248"
     CDS             complement(2563..3399)
                     /locus_tag="JOX41_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAY6449961.1"
                     /translation="MRVIKTLNNSLILCLDKQGKEVILMGKGIGFQLKKGDLVPADKI
                     QKVFKLDSLSDALKKDYIKLFEAAPDDLIICVKRIIDYANAKFDFKLNKSLFFTLVDH
                     LKHAIERSQKGIVFQNRLLIEIQKYYPKEFEIGCYAIQLINKKMNVQLPEEEAGNIAF
                     HIVNAQSEQANMEETMLSVRALKDILAMLGYLFPEKKVDKDSMLYLRFVTHLQFFIAR
                     MIKKEELPEKDDFLLASVKQRFPKEYRAALKIKEYVQEEMGASANQDELLYLTLHISR
                     VY"
     gene            complement(3417..4826)
                     /locus_tag="JOX41_002249"
     CDS             complement(3417..4826)
                     /locus_tag="JOX41_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAY6449962.1"
                     /translation="MQYKQLSAFPEKFLWGASISAYQAEGAYQEDGKQPSIIDKYQHT
                     EGVANFEVASDFYHHYKEDIQLFKELGLKAFRFSIAWTRIMDIENNKTNQKGISFYHQ
                     VIDECLNQGIEPIVTMYHFDLPYFLEEQGGWLNRATIDYFVDYVQVLLTEYGDKVNYW
                     LTINEQNTMILHPGAIGLPPSGELPSKKELFQINHHVLLAQARVIHLYHQLNLKGKIG
                     PAINLTAMYQATSSPEDAIAAHNWETLRGWSFLDVAVRGKYNYLFENYLNDRGLYPKI
                     EAEDQAILSSGKPDFIAINYYSTATIAASKNDGSDVSARAGDQQIMLGEEGVYRAAEN
                     PYVDKTPYGWVVDPTGLRLTLRKLYDRYDLPILITENGYGAPDIVEEDRRINDQDRID
                     YLAKHILAIQAALTDGVDVFGYLPWSAIDVVSTHQGFNKRYGFIYVDRTDENLKELKR
                     IKKESFFWYQKVIARNGLA"
     gene            complement(4840..6663)
                     /locus_tag="JOX41_002250"
     CDS             complement(4840..6663)
                     /locus_tag="JOX41_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAY6449963.1"
                     /translation="MDYREVGRNVLQQVGGKENVVSLTHCATRLRFELKDKRKADTKA
                     LEKTLGVISVVDSGGQYQVVIGNEVQTAFKEIQKEVGTSIKKGPSSDNQESIISRLIS
                     VISTTFTPMIPAITGAGMVKAILAVLTLTGVLSDSSQTYIILNTIADAAFYFMPVLLA
                     YGAAIKFDVNPILAITVAGILLHPNISQLFSTGDAVSFLGIPVLAADYAGSVLPIIFT
                     VWIMSYVEPFADRISPSFIKFFTKPMLVFLIMGPLALVVIGPFGTLLNDLIAMGAEWI
                     NGKAAWLIPFLMGGLQPFLVVTGTAWAMTPIATMQLSSTGSEMINGPGMLASNIAQSG
                     ATFAVAAKTKNKELKQLAVSTGITALMGITEPSLYGVTLKLKKPLVASMIGGAIAGLY
                     AGLSGLVRYAFVSPGLAALPAFIGENPMNIVHAIITCVIAFVATFIIAYLIGFDDTSD
                     ESEQTAIAEAVIVENPVKGTVCPISEVNDAVFSKGLLGKGVAIHPEENSIYSPVEGEV
                     ITILESKHAIGLRSKEGIELLIHVGIDTVNLKGEPFEVFVKAGDQVSAGQLLINADFA
                     AIRNAGYDDTVIVVVTNSENYAGISEASGSLKEHEPLMQIS"
     gene            complement(7506..7832)
                     /locus_tag="JOX41_002251"
     CDS             complement(7506..7832)
                     /locus_tag="JOX41_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449964.1"
                     /translation="MNKVNMNKKFIIIVIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKAILDNGSAININIEYYPKKDRIYVEIPYA
                     EVLMLN"
     gene            complement(7878..8240)
                     /locus_tag="JOX41_002252"
     CDS             complement(7878..8240)
                     /locus_tag="JOX41_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HAY6449965.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGADAVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVALAFIPVVFGAVAVIMGYLYRDKDEQMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            complement(8277..8491)
                     /locus_tag="JOX41_002253"
                     /pseudo
     CDS             complement(8277..8491)
                     /locus_tag="JOX41_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            8619..8954
                     /locus_tag="JOX41_002254"
     CDS             8619..8954
                     /locus_tag="JOX41_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAY6449966.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(9030..11027)
                     /locus_tag="JOX41_002255"
     CDS             complement(9030..11027)
                     /locus_tag="JOX41_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449967.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSFYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELTNTVC
                     ERLRNVGNNSVENALKENRGYFVKQGFTLERASKDIKRLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(11125..11400)
                     /locus_tag="JOX41_002256"
     CDS             complement(11125..11400)
                     /locus_tag="JOX41_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAY6449968.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            11632..12366
                     /locus_tag="JOX41_002257"
     CDS             11632..12366
                     /locus_tag="JOX41_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAY6449969.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            12405..13547
                     /locus_tag="JOX41_002258"
     CDS             12405..13547
                     /locus_tag="JOX41_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAY6449970.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
BASE COUNT         4372 a         2681 c         2089 g         4471 t
ORIGIN      
        1 ctccagataa gtgcgatact cagacgcatc attcagtaac aaccgaacgg ttgtcgtccc
       61 ccaacgaatg atcctagagg ggacgacaca aagacaatgg gaacactctt ctggcttgta
      121 cagaagagtt cctttgtaaa tcatggattt gagtcaatat cttggacaca ttttagtaga
      181 gacggttaag ccattttttc ttttgctaat tcttcaaatt cctgtggggt tagatagtga
      241 atcgagctat ggattcgatt tcggttataa aatccttcaa tgtagctaaa tagcgctcga
      301 tttgcttctt caaaatctga gtagctagtc gtgtagactt cttctttttt caatgaggca
      361 tggaaagatt cgattccagc attatcataa ggtgttcctt ttctactata agaatgcctt
      421 attttgttgg ttttaagcca ttgttccact tctcttgctg tgtattggct gcccaagtca
      481 gtgtgtagaa tcattccttc tggaatgtga taatgtattt ttgctttatt caatgtttga
      541 atgacacaat ccacagtcat tcgttttgaa aatgtataac taataatttt tttcgtgtgt
      601 aaatccatga ttgaagataa gtaacaccaa ccatttttct tagtaggaat gtacgtaatg
      661 tcagctgccc atttctcaca gatcgtttca gtagaaaagt cctgatttaa gagattctct
      721 tttgaaatga tcggtttatt agacctttga ggtctatatt ttttaactac aatcgacctt
      781 aaatttaatt gtttcattag cttttggaca tgtttaagag atactgaaat cccttctttt
      841 aataaaactt gatggatctt tgtggcacca tagcgttgtt tattcgtaaa aaaaattgtt
      901 gaaatcttct ttttcaactt attatttctg atttctgtag ctgtcaacgg tttattctta
      961 taaaaataat agacacttct agggatttct aataaccgac ataacaaaga aacagtgtaa
     1021 tccttacacc atttttcaat aaattgaaca agcgaattta ggttttccga gagaatatgg
     1081 ctgcggcttt ttttaagatt tcaagttcct catttaaacg agcattttct tttctcagtt
     1141 cagctacttc ttttccagtc agtcctgtgg actgatcagg taaatataaa ttcttccatt
     1201 tgtaaatcgt tgcttcagat aagccatatt ctttcgctaa ccctcgaaca gaacgtccag
     1261 tttgattcag ttcaacaatc atttgtttaa aattttcttc atatcgggtc ataaaaattc
     1321 atcctctcgt agataagttt aatttattct tgtctctacg aaaagctgtc taagatttga
     1381 tactaacacc aagttatctt tagaaccatt tcagatacat atgaaacaat tacatatgat
     1441 tttttcataa aaaaacagta ctgtctagta gtataaaata tacaaatttc ttaaaaattt
     1501 tttcactaaa atcactacct gaaacagtct aaaacactta tatatcaacg tttaatgaaa
     1561 ctatctccgt ttcatttcag atacaaataa atatagtcgg gctccaaatc cgaaaaaaaa
     1621 tacccccagt agcttatcct aagctactgg agatgtataa gtacggtcat ataacaacgg
     1681 ggtagggtaa ataaatgaaa aagatggaag aatcattatt caataacttt tttaaatact
     1741 tcgttgtaat cagttacctg tccgttctta aataccacag aataatcttt tttcccattt
     1801 tcaagtaacc gaagtggaat gtctttacca acttgctctg tcactgcatt actgatacct
     1861 gttagattag ctaataaatc tgataaagat tgagcatctg tagaaatctc tgtatcagta
     1921 tttatcgtga ttcctttatc ttcatttaca agcttccaag taggtggtat agctgtgtat
     1981 gtttcgatga atgaatcaat tctttcatct atcgtcttcc cagtatctac ttctgtctca
     2041 ttactcttag atgaatcgat tctttcatcc atcgtctgct ccgtaactgc ttctgtctca
     2101 ttattctcac cggaaactct cttcacaccc aaacttatat attgtccatc tttagtgtgc
     2161 atagttaaaa ttcccacgct tttactaata aattcactat aaccagttct ttcaatagag
     2221 acttcaatgt atttcacact atcatactca aaagaaaaat agacatgtaa aagcattttg
     2281 ttgtttacat ctacataata atcctttgac tctacttgag accttcctat acggaataca
     2341 gctttactgt ctgatatctc tataccagca tccttattat taatctgcca atctccaagt
     2401 agctcttctg gcaagctagt agtttcttgt gaacacttta ccacttcact ggtagaggtc
     2461 gaaacattca cctccgcact gttagaagaa ttttccaagg aatcaggagc cttagcacaa
     2521 ccaacaagtc tttatatatt gtgcagccga tattttcttc attcagtaca cccttgaaat
     2581 atgcagtgtt agataaagca gttcgtcctg atttgctgag gcacccatct cttcttgaac
     2641 gtactccttg attttcaagg ccgcccgata ctctttcgga aaacgctgct tcactgaagc
     2701 cagcaaaaaa tcatccttct ccggcaactc ttccttctta atcattcggg caataaaaaa
     2761 ctgtaaatgc gtcacaaatc ttaagtaaag catcgaatct ttatcaacct ttttttcggg
     2821 aaacagatat cctagcatag ccaagatatc ctttagtgct cttaccgaga gcatggtttc
     2881 ttccatattt gcttgttcac tttgggcatt tacaatgtga aacgcaatgt ttccagcctc
     2941 ctcttctggc aactgaacat tcattttttt gttgatcaat tggatagcat agcagccgat
     3001 ctcaaattct tttgggtaat acttttgaat ttcaatcagc aggcgatttt gaaaaacaat
     3061 gcctttttga ctgcgttcaa tggcatgctt caagtgatca accaaggtaa aaaatagact
     3121 tttattcagc ttaaagtcaa acttggcgtt ggcataatcg ataattcgct tgacgcaaat
     3181 aattagatca tccggagcag cctcaaacag tttaatgtaa tcctttttta gagcatcaga
     3241 aagtgaatct aatttaaata ctttttggat tttgtcagcc ggaaccaaat cgcctttctt
     3301 tagttgaaat ccaatccctt tccccatcaa aattacttct ttgccttgct tatctaagca
     3361 aagaattaaa ctgttgttta acgttttaat tactctcatt agattcaccg ttctctctaa
     3421 gctaagccat ttcttgcgat tactttttga taccaaaaga agctttcttt ttttattcgt
     3481 tttaattctt taagattctc atcggttcgg tcaacatata taaaaccata acgcttattg
     3541 aagccttgat gggtactaac aacatcaatc gctgaccaag gtaaataacc aaaaacatct
     3601 acaccatctg ttaaagctgc ttgaatagcc agaatatgtt tggctagata atcaattcga
     3661 tcctggtcat taattcgtct atcttcctca actatgtcgg gtgccccata gccattttca
     3721 gtaattaaaa taggtaaatc atagcgatcg tacaatttcc tcaatgttaa tcgtagtcca
     3781 gtagggtcaa ctacccagcc atatggcgtt ttatctacat aaggattttc agctgcccgg
     3841 tagacacctt cttctcccaa catgatctgt tgatcccccg ctctagcgga aacatctgat
     3901 ccgtcatttt tgctggcagc gatggtggca gttgaataat aattaatcgc aataaaatcg
     3961 ggtttaccgg aggataaaat tgcctgatcc tctgcctcaa ttttaggata taatccacga
     4021 tcattcaaat agttttcaaa caaataattg tattttcccc gaactgctac atctaagaaa
     4081 gaccagcctc tcaatgtttc ccaattatgg gctgcaattg catcttctgg actggaggta
     4141 gcttgataca tagccgttaa attgattgct ggaccgattt ttcctttaag attcaactga
     4201 tgatacaagt gaattactct agcttgagct aataaaacat ggtgattaat ttgaaagagt
     4261 tctttttttg aaggcagctc tccacttggt ggcaaaccaa tcgctccagg atgaaggatc
     4321 atcgtgtttt gctcattaat tgtcagccaa tagttcacct tgtcaccata ctcagtaagc
     4381 aatacctgta catagtccac aaaataatcg atagttgctc gatttaacca accgccctgc
     4441 tcctctagaa aataaggtaa atcgaaatgg tacatggtga caatcggttc gattccctga
     4501 ttcaggcatt catcaattac ttgatgataa aaagaaattc ccttttgatt ggttttatta
     4561 ttttcaatat ccataattcg cgtccaagcg atggaaaagc gaaaagcttt taagcctaat
     4621 tctttaaaca gctgtatatc ttctttatag tgatggtaaa aatccgaggc aacttcaaaa
     4681 ttagctaccc cttctgtatg ctgatacttg tcaataatag acggttgttt cccatcctcc
     4741 tgataggcac cctctgcctg gtaggcacta atggaggcac cccataaaaa cttctctgga
     4801 aatgctgaaa gctgtttgta ttgcacaaaa atcctctcct taactaattt gcatcaatgg
     4861 ttcgtgttcc tttaagcttc cgcttgcttc actaattcct gcgtaatttt cactgttggt
     4921 cactaccaca atcactgtat catcgtagcc agcgtttcta atggcagcga aatcggcgtt
     4981 gattaataat tgtcctgctg acacctgatc tcctgctttt acaaatactt caaagggttc
     5041 cccttttaaa ttcacggtgt cgatccccac atggatcaat aattcaatac cttctttaga
     5101 acgtagacca atcgcatgtt tagattctaa aatagtaatg acttctccct caacaggtga
     5161 ataaatgctg ttttcttctg gatgaatggc tacgcccttt cccaatagtc ccttagaaaa
     5221 gacagcatcg ttcacttcag aaataggaca cacggttcct tttaccggat tttcaacaat
     5281 gactgcttcg gctattgccg tttgctctga ttcatcagaa gtatcgtcaa atccaattag
     5341 ataagcaatg ataaaggttg caacaaaggc gattacacac gtaataattg cgtgaacaat
     5401 attcattgga ttttctccaa taaaggctgg taaggctgct aagccagggg aaacaaaggc
     5461 atatctgact aaaccgctca agccagcata caaaccagca attgcaccac caatcatgga
     5521 agcaactaat ggttttttca gcttcaaggt tactccatag agtgaaggct cagtaattcc
     5581 cattaaagca gtgatcccag tggacacagc tagctgcttc aactctttgt ttttagtttt
     5641 cgcggctaca gcaaaggtag cacctgattg agcaatatta gaagccagca ttcctggccc
     5701 attgatcatt tcagaacccg tactgctcaa ttgcatagta gcgattggcg tcattgccca
     5761 agctgtaccc gtaaccacca aaaatggctg caaaccaccc atcaaaaatg gaattaacca
     5821 agctgctttg ccgttaatcc attcagcccc cattgctata agatcgttca gcaacgttcc
     5881 aaacggtcca atgacaacca acgctaaagg ccccataatt aaaaatacca gcatcggctt
     5941 agtaaagaat ttaataaacg aaggcgaaat tcgatccgca aagggctcta cataggacat
     6001 gatccaaaca gtaaagataa tcggtaaaac tgatcccgca taatctgcag ctaataccgg
     6061 aattcctaga aaagaaacgg catcgccagt agaaaaaagc tgtgaaatat ttggatgaag
     6121 caaaatgcca gcaacagtaa tcgccaaaat tgggttgaca tcaaacttta tggctgcccc
     6181 ataggctaat agtactggca taaaataaaa ggctgcatca gcaatagtat tcaaaatgat
     6241 gtaagtttga ctactgtctg atagtacacc agtcaaagtc aagacggcca aaatggcttt
     6301 taccatcccg gcacctgtta tagctggaat catcggtgta aaggtggtag aaatgacact
     6361 aatcaatctt gaaataatac tttcttgatt gtctgaagag gggccctttt taattgaagt
     6421 tcccacttcc ttttgaattt ccttgaaggc tgtttggact tcattgccaa tcaccacttg
     6481 gtattgtcca ccgctatcca ccacactaat tacaccaagt gttttttcta aggctttcgt
     6541 atcggctttc cttttatctt tgagttcaaa acgcagtctg gtggcacaat gggttaagct
     6601 gaccacattt tcttttcccc caacctgttg caatacattt cttcctactt ctctgtaatc
     6661 cattattctc tctccttaaa gcagtaaaaa agaccaagtc aaaccacgcc ccaatcaaca
     6721 ttgaagtgtt agtttgtctt ggtcttgcct gcataatcag taacatgcca ataacgttat
     6781 tttgctgtaa tccaataata gcacattatg atagcgcaat caacagggaa tttaattttt
     6841 tatcttttcg tttgaccgta tagggtaata taacagttag atcacatcaa ctagggtata
     6901 tctgcgtata cttactgcta aaataagtat atctaatatt aactatacca gtaaaaccat
     6961 tcctacataa ccagcgggaa attcccaaaa tcgtgaaagc atcaaaaatg catataacgg
     7021 atcacacaac ttcaacaatt ctgctcttgg gaaaaattga tgaatttggt gagtaaagga
     7081 tggaataaac agcattccaa caatataggc aacaatagtg atacttgttt ttttggtaaa
     7141 aatcagtaag caatagccaa tttcaatcat tccgagatat aaaggtatcg atagaatgat
     7201 ttgggctagt attcttaaaa attaactagc aaatgtttaa actgatttat ttctaatcta
     7261 catgtagtaa gtatttcaat tccaccaatt atcaataaaa ataccaaaca tatccataat
     7321 aattttttct ttttcatttc ttttatattg ttataacagt gaataacata aaaattcccg
     7381 acaatcattg taatattttt ttgtcacctg tattagtatt taatttatag gaaactataa
     7441 aaactcccta gtgaatttac acctttggga gttcctgttt ggacggtatg cataatacat
     7501 ttaaatcaat ttaacattaa cacctcagca tatggtatct ccacatatat acggtctttc
     7561 tttggatagt actcaatatt tatgttgata gcacttccat tgtctaatat agctttagcc
     7621 cggtatgtgt tatctccatt ttcatgagta atcgtcacat catcacatga tcgatttaag
     7681 ttgtactgtt cttgtaaaat ctgtgttacc aatggtttcg atgacttctc taatccagat
     7741 gtacctgtca tttttgaaaa aatgatacct ataatagcca agacaacgat aactataatg
     7801 ataaacttct tgttcatatt tactttattc aactttttat ctcctatctc caaaataatt
     7861 tgctcttatc cctcttatca gtacattgac atccctaaaa gtacaccaaa gattgctcca
     7921 gctacccctg ctatcatcaa aatcgtaccc atttgttcat ctttatctcg atataagtag
     7981 cccataataa cagcaacagc accaaataca acaggaataa atgctaacgc tactaccata
     8041 gaaatccaac caataatcaa atacagcttc cctgtctctt gtccatgtac gatttgttcc
     8101 ttcatttcat taattgtctg ctcagtactt ttctttactg cgtctgctcc agttgtctca
     8161 tctgtttctt gtagtgctcc gcaaaactgg caatacttac tttcatctgt tatttctttg
     8221 ccacattttc tacaatacat gtcttctcct cctaaaaaca ttcaattgtt tattagttaa
     8281 ctgtttactt tattaaatac atcagaaaac agctcattca ttggtacact taatatctca
     8341 gaaagcatct tcatttgata gggtttagga atcgttctcc ctgtttgcca cgaacttaca
     8401 cattgctgtg taacattcat ttttttgcta actccgtttg agaaagtcct ttttcttttc
     8461 tgtatcggct gagattactt acttttttca tgattctccc ctcctgtttt attatataca
     8521 acaatatgat gtatttcaac tcataaaata taaaaaaact tcaaatacca ttacaaatac
     8581 aacaacttgt tgtactatac tgagatgggg gtgtattaat gaaacagaaa caatatgcaa
     8641 aggtcattag agaaaagcga aaagctctcg ggtggacaca aaaagaatta gctgaaaaaa
     8701 tcttctctac acaacaggca gtagcaagat gggaaaattc tgtaacagag cctaacctcg
     8761 atagcttaac cgctctttct agagccctag gaacccctgt aagccatttt ctagacaatg
     8821 ttgtcgtaga ttatgaggaa gagtttttgg ctctctatcg ttctcttagc actgaagatg
     8881 cagttcgaac aattgactat atgaagctat taaaaaggca agaaaatgaa cgcaatcagc
     8941 tattgaaaga ttgaaaaata aataacccac cgaactttaa cggtgggtgt attgagatga
     9001 aataagatta agagctatgg ataacctgtc tagtttaata caattgggtc ttttctcttc
     9061 cttactctcc gtccatcatc tcttgttaca cttgtaaatt gataaagagg aactaattca
     9121 actcctgata atatcaattc ttttattact tcatctatcc ctgctccttt tgctaggtag
     9181 actaaaaaac tactacttgc tttcacattg tatagtctct taatatcctt agaagctcgt
     9241 tcaagagtga atccttgttt aacaaagtag cctctgtttt cttttaaagc attttccacg
     9301 ctgttattcc caacattacg tagacgttca caaacagtgt tagtaagttc tttctctgtc
     9361 attagatatg ttccttgcca cgataagccc tgtaaaactt catgtgcttc atctaaaatc
     9421 aattgttttt ccttgctaag ttctgatcgg gaattttgag gaaatactct tttagcctct
     9481 ttttcgttaa aacatatctt aacccattca taagaaaaat attgatatgt aaaatgaaat
     9541 ttttccagaa gtggaaggat atcttcattc aatttttgaa tcacagaagt tgcattaaaa
     9601 acgtctaatc gatagacatt gcttctctta tgattaaagt ttcctaacgc tttctcttcc
     9661 tttaacctat ttaggtattc gagcatcttc aaaggaacat cttcatcatc taattttttt
     9721 atcaatccta taaaagtcat aagtgatagt aacttattac atttatctat gtcataagtt
     9781 ttaccatagt aaaaactcat ttttttagct aattgttccc ccgacaaaat acaagtcaca
     9841 ctttccttac tatcatcaaa aaaattaaca tcagaaagca agacatcata gacacgtcgc
     9901 atttcctcta gataattcct tattgtcctg aaaagtttgt ctttcattga ttcaagagtg
     9961 tcaaaaagta cttttgattc ctctttcaat tttcgaaaat gtgtaggata caagtctagg
    10021 ttctctaata gccaattaaa tgtttctacc cgactgtctt tctttaaaat tagcatcaca
    10081 actccaataa aattttcact gatatcacaa ttactggaat gacaataaaa aatggaatgc
    10141 ccagttttac tggtaaaaat actagcagag ggattatgat cgttgtgaaa cagacatctt
    10201 aagtttttac ttgacttaag taatttattc atatcaatgg ttaacaatct ttcataaatc
    10261 tcattaaaag acatgtcgga ggaatcaaac aggcagtctt taaaccactg tttcatttct
    10321 tctttgtcgt cattttttat caacttaaca aaatcggttt cattgactag ttcatactct
    10381 ctccctgaat cactttgaca atttttagaa catgtcatgg taaaatcaat cggaagctca
    10441 gtaatatcta acatgttgtc ttcattaatt attatcactg catctgactt atatcctcca
    10501 aaaaacattc tattcgaagc atttacattg tcatcacacc cggggatgtt ctttttcaag
    10561 tattcgtaaa cagcaaccat tttaccatag tcagtaattg cttcttttaa tagaaagaca
    10621 atcttgtatt tttctagatt ttcagagtac cgaatacttt tttgtatcgc aaacgcagaa
    10681 ttatgaacta aattgataga taaaaccttt tctatgctta agtatctact atcatcttta
    10741 ctcaaatcta ctaccttccc cttctcatct ttaacagtgt tatcgacatc cagaataatt
    10801 actctggttt ccacaaaact ctccttgtca ttgcctttat tctttgtctt gcttggaata
    10861 aatgattgtg atgaatttag tatctctaca aactcatctc ttgtaacttc tctatagtta
    10921 tctaaacacc tatctcttac atcagttttt tctttttttg taactggctt ctctaataat
    10981 ttttctttat ctacataaat tggaatatta atcattgatg tttccatttg tgtttcctcc
    11041 ttataaaatt ctgttaaaga ctaaaacata cagataataa aaacaaactc tttattacta
    11101 tatgttttag tcttatttgt ttactcaacc tttataccgt tccatgaaac tatcaatatc
    11161 agatttttta aatctaatga ccgtatcaat ttttataaca ggtaacccgt attgagaaac
    11221 atattttcta atcgttccta ctgatacacc tagatattca cttgcctgct gatagtccat
    11281 atactctaga gtgactccag aaataatgtc ttctagcata ggctttagca ctgtaattat
    11341 ctctttcact tgttgttcaa cttgtataga aacaatgcta tcaatgattt gtagagacat
    11401 atttccccct cctttcgtga ttgcttgaac aaattttcta agaattatct tcgtattttt
    11461 tgctcaaaat aaaagtattt tgttattaac cgattaatca aacaaaaaat gattaccagt
    11521 tcatcgacat acacataata cctcgataaa aaagaggtgt caatatcttt gtaaaattta
    11581 tttacaacac ccctttttcg aggtatacta attttaggag gtgtggtcaa tatgataaaa
    11641 cgtccaccaa taaattattt agaacgaaaa aagatactcg gaacaaaaat aaaagctata
    11701 agaaagagta aaaaattaac acaaccagca tttggtctta tgattaacaa cggtcaatta
    11761 attgacaaaa aaactatcta cgaatgggag aagggaacct atttaccaat accagagcga
    11821 ttatcccgaa ttgctgattt gggaaatatg agtatagagg agttagtttg tggcaatgta
    11881 gaagaatata ttttgggaat tattctttat agagatagca ttgtactaga tggtataaca
    11941 tttccagata aaaacctgtt ccagcatctt cgtcaacagt tcccaccagt acactctaat
    12001 ttagatacat ggctggatag atattccaaa ttagaaccag agatgcaaga atttattgct
    12061 aacaagactt gtaataaagt taaaaatgaa aaaattagtc ttttcaatat cttaaaaata
    12121 gaagaattat tcatcaatgc tattgtagaa gaatttgaca ataacattct tttcctcact
    12181 agcagtatag aagaactact agaaagaatg gtagatgaat ggctacctat tcaattgaaa
    12241 gacatgtctt atcccgaaga agctgtgaga gaaattactg ataatataaa caagctagaa
    12301 caaacgattt catcaattgg gaaaaaatac actaagaaaa aaatgaaggg aggtgatacc
    12361 atctagtggt aagtactcct tgtaaactaa gaggagatga tttcatggca aaaatatcaa
    12421 agtacaaaaa gaaaaacggt caagtggcgt ggatgtataa aggacacatt gccaccgatc
    12481 cacgaactgg tgaaaaaata aatactacga gaagaggttt tagtagcaaa caagaagctc
    12541 aaaaagatta tgacgagtac agacatcaaa tattatacgg tgttaaaaag aaagcacctg
    12601 atatgacatt tgaagacctg tataatgaat ggataactca tcagcgtacc agtgttaaag
    12661 cttcaacaat cgcaatctca gtaagatacg caaataatca aatacttcca gcatttggta
    12721 agcttaaact atcgaatatc tctgtcccat attgtcaaaa agtggtagat gaatggcaca
    12781 gtaaatatga aagttacgat tatatgagaa aacagactgc acaaatttta cgctacgggg
    12841 ttgcaatgca atatattgac aataatccta tggaaaaaac acttcttcca cgaaaaaaag
    12901 agtatgagaa aaatcgtaaa ttttactcaa aagaggagct taataattta ctggatgctt
    12961 ttaaagattt tggtaacatg aaacaatacg ccttcttcag attattggca tacacaggta
    13021 tgagaaagag tgaagtactc gctttacagt ggaaagacat agacacgttt aataaagaac
    13081 tacatgtcaa taaaactctt gctgtagatg aatttggtaa agttataatt caatctccga
    13141 aaacaagagc ttctagacga gttatctctt tagatactga gactctttct atcctcaaca
    13201 actggaaatt acagcaaaaa gaagagtatt taaaacttgg atacaatact agctctaaag
    13261 agcaacatgt ttttacaaca gttaaaaaca ctctatacat tccaaacact gttaatgatt
    13321 ggttaagata tattttgaaa aaatataact tgcctcgtat tacacctcat gggtttagac
    13381 atacacatgc tagtttatta ttagaagcag gagaatctgt caaggtagtt caacaacgat
    13441 tagggcatga aaatagtaaa gtgacattag acatctatgc acatattaca aataatgcac
    13501 ctaagaaaac aggtcaagac tttgctgata tgatggctca tcagtaaaag agctggtcaa
    13561 aatctggtca tttctagtat acaggcaaaa caaaaaagct agaaccctta tat
//
LOCUS       DADLIO010000070        13185 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.073, whole genome shotgun sequence.
ACCESSION   DADLIO010000070 DADLIO010000000
VERSION     DADLIO010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13185
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.073"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            226..1920
                     /locus_tag="JOX41_002259"
     CDS             226..1920
                     /locus_tag="JOX41_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAY6449971.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEIVKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNGATCSAVKSCGLQVV"
     gene            2608..4485
                     /gene="ltrA"
                     /locus_tag="JOX41_002260"
     CDS             2608..4485
                     /gene="ltrA"
                     /locus_tag="JOX41_002260"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAY6449972.1"
                     /translation="MTKETSPKDRKLRHAEYYGMTEIFDKIYSKSLKGDNFKNLMQII
                     ISDNNIVLAYRNIKRNHGSVTRGEDGVTIKDIENLNRNEFVEIVRKRFAHYNPRKVRR
                     VEIPKYNGKLRPLGIPSIWDRIAQQCILQVLEPICEAKFNNHSYGFRPNRSAEHAIAD
                     CMARMNQSHMEYVVDVDIKGFFDEVNHTKLMRQIWSMGIRDKQLLLIIRKMLRAPVVL
                     PNGKLIYPTKGTPQGGILSPLLANINLNEFDWWIANQWEEKDAKELKHHFRKNGAWDK
                     GNIYHKLRKSTTLKEIYLVRYADDFKIFCRNYNEAKKVFYATKMWLQERLKLPISEEK
                     SKITNLSKEESEFLGFTMKLVTKGNKKVVNTHIGTKAQSMIKVKLKKQIKRIQKSPNS
                     KDTFIYIGVYNSMVIGIHNYFKIATHCSVAMRKIARELRPSFEIRLREQGISKEGQYG
                     KYEGYKPYLRSGQIRYIRGFPILPVGYIQHRHPMCKKRNINKYTEEGREAIHKKQQTV
                     EEWKISWLCSNPVLSKRATIEFADNRISKFIAQKGRCAVTGEELILSEMHCHHIIPYH
                     ESKSDSYENLVIVTEEVHRVIHATQSETIEELLKYLKLNPKQKEKLNELRLKVGNEEI
                     S"
     gene            4616..4993
                     /locus_tag="JOX41_002261"
                     /pseudo
     CDS             4616..4993
                     /locus_tag="JOX41_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
     gene            4993..6198
                     /locus_tag="JOX41_002262"
     CDS             4993..6198
                     /locus_tag="JOX41_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HAY6449973.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWLFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYK
                     LLPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKF
                     PNSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMS
                     IITSNKLTEYDEFAIKHWGEGGNNNGTITGEWTNPFPGSSLDKSSFSGGQLFGTNPGG
                     EFRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVY
                     QEFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDP
                     LPFLNSSKK"
     gene            6214..6858
                     /locus_tag="JOX41_002263"
     CDS             6214..6858
                     /locus_tag="JOX41_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449974.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQAANTYKIEEVAK
                     NASEKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPTDDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVIDFSYFTR"
     gene            6869..7675
                     /locus_tag="JOX41_002264"
     CDS             6869..7675
                     /locus_tag="JOX41_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449975.1"
                     /translation="MSKKKGERQRFKKRKSYLRWLGIFMILGFLILASPIYTNQKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIRAKVIKVSDDYFAVKLTHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIFYIH
                     EDKVKDHVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQLKDQEEIIQKLQEKIDRMTKEKI"
     gene            7697..7927
                     /locus_tag="JOX41_002265"
     CDS             7697..7927
                     /locus_tag="JOX41_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449976.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYVAAKKYFTADNK"
     gene            8473..8748
                     /locus_tag="JOX41_002266"
     CDS             8473..8748
                     /locus_tag="JOX41_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449977.1"
                     /translation="MDLLIRNIEEKYINKIDKRCEELTVKTGKKWSRNQYLKVLIEND
                     FDHALLNYKKDQFDRLLEKFVDIQTYNTKTLEEYIATNNQLIGLLIE"
     gene            8790..9212
                     /locus_tag="JOX41_002267"
     CDS             8790..9212
                     /locus_tag="JOX41_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449978.1"
                     /translation="MAKATRKHVYLYDMHIEVLDEIISTHEDISNYSEAVRHLCMMYD
                     PKIEEKINPIQIKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAEERVE
                     GKIKSNQTKKYSSKLKKPVNESVHTRVDPFDPTKILKR"
     gene            9231..10823
                     /locus_tag="JOX41_002268"
     CDS             9231..10823
                     /locus_tag="JOX41_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449979.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEMERRTPEE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMEHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQREQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVISHDNSYLEKMGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEIENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPEKRSEWNYGDENRTKLSPFTRGKLDELTKYVLTKEPGYQEYIQ
                     ISKALKEEAKSLYGESKRETKNAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVN
                     QMQSIYNERSFRTLKQLPTNEYKYSYQEFVKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            10835..11170
                     /locus_tag="JOX41_002269"
     CDS             10835..11170
                     /locus_tag="JOX41_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449980.1"
                     /translation="MKQYLDQWKVIEGSLKEERIEQLPDCLEKEHLFQISEMLRNEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEINEEGINNFPCESI
                     EESISLTEC"
     gene            11317..11511
                     /locus_tag="JOX41_002270"
     CDS             11317..11511
                     /locus_tag="JOX41_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449981.1"
                     /translation="MTQTTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQNGNI
                     LTLNLTTKMFVDAVENYPFV"
     gene            11543..>13185
                     /locus_tag="JOX41_002271"
     CDS             11543..>13185
                     /locus_tag="JOX41_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6449982.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNNQFQKLFDHQKLTNGQ
                     PMNDKRNGRSWFNQQEKIENKIQSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKEKDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNHPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSSEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQAR"
BASE COUNT         5050 a         2052 c         2772 g         3311 t
ORIGIN      
        1 ccactctaca aaaaagaatt gatcaagatt ctgtatcgaa tgaacaatat gaatgatgag
       61 taggaatgga gaagagagaa tgaaatatcc gttgatatgg ttagaaaaag atgttccgaa
      121 ggaagagacc actagaaaat ttcctcacac tttaagcctg ggtaagttgg gaaaagggca
      181 atcttttaac caagtaaaga atcaaacaag aagaggtgac tgtacatgtt agaagcaatt
      241 aaaacagctt tttcaccaca aaatgatcaa aaagtacttg atccattaaa gcaactagga
      301 aatcgggaaa tagaaattgt aaaatccaaa gggtatgatt tagatttttt aaaacaagtg
      361 atgccacaag gtgggttaaa ttttgatgaa gaatatgtga cgtatggtaa tggttattca
      421 cgatgtgtga cagtttatca ctacacaaaa aatcctacgc ttttttggtt ggccaatctc
      481 atgaacaatc ctcatacagt ggccacactc gatgttagca cagatgaaaa gcaaaaagtg
      541 attgatcaaa tcaatcgtgc cttagatgaa ttaaatgatc gatcagataa tgaacgaaaa
      601 gcgactgacc gaaataaaag cgcggaagaa tacctggaac tagcggaata tgctagaaaa
      661 ttgacttcta atggggaaat ttctaagcaa gtcaaagtga gagtacatgt ttacggaaac
      721 acgattcaag aagtagatga acgagcgcag gaactgatcg aaaatctcaa agggatggat
      781 tatcgtgcgg tgacttatct gcataaaacc aaacgagatt ggcaatcgat gtttaccatg
      841 ttcgatgaac aagctgaatg gttcggaaat atcaaagggc aatcactacc atcgttaaac
      901 attggcggag gtttcccgtt ccaccaccaa acgctaaaag atccaggagg gacacaatat
      961 ggggaaacca tgacaggcgg cccatttgtc tggaatgcga cgtataaaaa tagtgtacgg
     1021 ttgtctacta ataccttgct tctaggaatg atgggagctg gtaaatcgac cgttcttaaa
     1081 atgatcgcgg aagcccattt agctgcagga gactttattt ggggctttga aaagggaaaa
     1141 gactttattc ctttcttaaa ggaatataac ggtattatgg tgcgtttaga cggatctgac
     1201 ggaatgatca atcctttaga gatatttgcc acacggacgt atgatgaagc atccagttta
     1261 tatgacgatg gatcagtcaa agatttgaag atcaatgaag cagcgtccta tcaaacacac
     1321 ttagacaaag tggtctatca ggtacagtta gtgagtcctc agctaaaagg aacgatgaaa
     1381 gcagaattta agacctactt aaatcgtttt tatgaagagt atggaacagt accacgcggc
     1441 tttacttcct caaattcgcg ttcaaatact gatacgcaag tcacagggaa agatccagaa
     1501 gcttatccga cgttcaaaga atttttagac tttttaggac aactggaatt accaggtgct
     1561 tcccaagaga aaaagaatcg aaaagaagaa atggaatcca tcgtagaatc cttatgtgag
     1621 acgtatggca tgatttttga tggtcatagt acgattcgac accttgacca acaacagttg
     1681 gtcttttttg acattgactc tattacaggc ttagatcgag gggtacaaca atgtcaaatg
     1741 tacatggcta tgacgttgat ttggaatcag gcattgattc aaggaagaag acaacgacgt
     1801 ttaattaaag aaaaacaaat ggaagaacaa gacttcaaac gcttcttggc gatgattgat
     1861 gagtgccata atggtgcgac ctgttctgca gtgaaaagct gtgggttgca agtagtctaa
     1921 aaactattgt aataactctt ataacgagaa gtcaaatgag tgggtaacgc cacaaagggc
     1981 ttccactgat actccgacat gcaacaagta gtttatgcag accaacgttg tgtgaagctc
     2041 ggtgaagtcg gctgaaggat accgtaaggt aaaagaaata gtgaatacca cgaaagttct
     2101 ctagaggtaa agggtgtatc cgataagtcg ggtgtccaaa aaaacttaat atggtgagta
     2161 tgtacaaacg tactgacgaa ctagcgaatg tactgtccga aaggcatagc tcctagaaat
     2221 gggagagaca gtgagcaaaa aatcactcat tgtgctaact tgtggttgag taaaagtcgt
     2281 tgttatgaaa gaccatgctg cgttacaggc gtaggagaag ttagggggca aaagctagca
     2341 tctaagttaa ggcatgtgga tagatataag ggaacagggg aagccatcaa catggagagt
     2401 gcatactcga tgaagtggta gtaagaaata tgtgaatgac aaataactta ctttagtgat
     2461 ggtgaaagta gagtcacgac tgatgaaggt tctgtaatgg aactggagga acaggctcga
     2521 ttcgtctgta aaagtcatga aacccgttca accatgggat tctcgtatga ctaaaaaggt
     2581 cacgagccaa ttggagcgtg ataaaccatg acaaaagaaa caagtccaaa agataggaag
     2641 ttgcggcatg cagaatatta tggcatgacg gaaatcttcg ataagatata ctccaaaagt
     2701 ttgaagggag ataatttcaa gaatctaatg cagattatca tttctgataa caacattgtc
     2761 ctagcatatc gtaatatcaa gagaaatcac ggtagtgtga caagaggaga agatggagta
     2821 acgattaaag atattgaaaa tctcaaccgt aatgaattcg tagaaattgt taggaagcga
     2881 ttcgcacatt ataaccctcg gaaagtaagg cgtgtagaaa ttcctaaata taatggtaaa
     2941 ttaagaccgt tgggtattcc atcaatatgg gatagaatcg cgcagcaatg catcttacaa
     3001 gtattagaac caatatgtga agcaaaattc aataatcaca gctatggttt ccgcccaaat
     3061 agatcagcag aacacgcaat agcagattgt atggcccgaa tgaatcaaag tcacatggaa
     3121 tatgtggtag atgtagatat caaaggtttc ttcgacgaag tcaatcatac taaactcatg
     3181 agacaaatct ggtctatggg tatacgagac aaacagcttc tcttaatcat taggaaaatg
     3241 ttaagagcac ccgtagtact tccaaatggg aagttgatat acccaacaaa aggaacacca
     3301 caaggcggaa tacttagccc attacttgcg aacatcaatc tcaacgaatt tgactggtgg
     3361 atagcaaatc agtgggagga aaaagatgcc aaagagctaa aacatcattt taggaaaaat
     3421 ggagcttggg ataaaggtaa tatctatcac aagctcagaa agagtacaac tctaaaagaa
     3481 atatacctag tgagatacgc agatgatttt aaaattttct gtagaaatta taatgaagcg
     3541 aaaaaagttt tctatgcaac taaaatgtgg ttacaggagc gtctaaagtt accaatatct
     3601 gaagaaaagt caaaaatcac aaatctttca aaagaagaaa gtgaattttt aggctttacg
     3661 atgaaattag tgaccaaagg taacaaaaag gttgttaata cgcatatagg tacaaaagca
     3721 caaagcatga ttaaagtgaa actaaaaaaa caaatcaaac gaattcaaaa aagtcctaat
     3781 agcaaagata cctttatcta tattggagtc tataacagta tggttattgg gattcataat
     3841 tacttcaaaa ttgcgactca ttgtagtgta gcaatgcgaa aaattgcaag agaactcaga
     3901 ccaagttttg aaatacgact acgagaacaa ggaatctcaa aagaaggaca atacggaaag
     3961 tacgaaggat acaagcctta cctacggtca ggacaaatac gatatataag agggtttcca
     4021 atattaccag tagggtatat tcaacacaga catccgatgt gtaaaaaaag aaatattaat
     4081 aaatacaccg aagaaggtag ggaagccatt cataagaagc aacaaaccgt agaagaatgg
     4141 aagatatcgt ggttgtgtag caatccagtg cttagtaaga gagcaacgat tgaatttgcg
     4201 gacaatcgaa tttcaaaatt catcgctcaa aagggaagat gtgcagtaac aggtgaggag
     4261 cttatcttat ctgaaatgca ttgtcatcat attatccctt atcatgaaag caaaagtgat
     4321 agctatgaaa acctagtgat tgttactgag gaggttcatc gggtaataca cgctacacaa
     4381 agtgaaacga ttgaggaact tctaaaatat ctaaaattaa atccaaaaca aaaagaaaaa
     4441 ctcaatgagt tgagattaaa agttggtaac gaagaaatat cttaataaat atttgtagga
     4501 cgggaaaaca gaatgtcttt tatagacgag ggaacgccgt atgcggtgaa agtcgcacgt
     4561 acggtgtgga ctgggggaaa agacggagat aatatcaaac tcttacctat cagtatcgat
     4621 taatccagat tttattgaaa cggtaaatta tgtcacaaac tttcaacgag aaatgcgtaa
     4681 agtagaagca atgactgttt tagctacaca atccccacaa gaaatggtgc cagaaaatat
     4741 gtcttctgat aacttctcga aactgaagaa agtctttgaa ttttcttcta cgaagatctt
     4801 tatgcgtatg gatgaatcta ttttacgtca tatagaagga ttagtgggta aatcaatgac
     4861 gaactcagaa ttagaatcca ttcctcaaca aaatcaagga gacgctgtga tcaattttgg
     4921 ctcaaaagaa accattcgtg ttcattttag tccgaacaaa cgtcaattaa aattgtttga
     4981 tggaggaaaa taatggaaaa ccaaaatgaa agtttaatca agcagtatgt taagcgtcgt
     5041 gcaaagcggc gcttattttt gtggttgttt ggtacttctg caggtttgat tactattttg
     5101 atcactgtgt tcgtgaccct atttctaata cttgcggcgg gctcgattga taattcggat
     5161 tcagattcaa gcagtggtgg cgaagctttt acaggagaat attcggaagg cttaccgatt
     5221 tataaagaaa tcaaaggaag aggccctttt tctgatgaga ttgcgcaata tgccgtaggt
     5281 gcagcagtga aatataaatt attaccaagt gtgatccttt cgcaatacgg ttacgaatca
     5341 gcgtttggta catcggcgtc cgcaagaaat gatctcaact attttgggat tacttggttt
     5401 gatggttgtc tgtttcctaa aggaactgca cgaggaattg gtggcattga aggtggctgg
     5461 tacatgaagt ttcccaactc aaaagctgca ttttcctatt acggctttat ggtagccaca
     5521 caatccaatt ttaatgcttg tgtaggaaat aaaagccctg gcgcaagctt attgatctta
     5581 ggacgaggcg gttatgccgc tgcaggaatt acggaagata gtccgtatta tacaggttgt
     5641 atgtcaatta tcacttctaa taaattaacc gaatatgatg aattcgccat caaacattgg
     5701 ggtgaaggtg gcaataacaa cggcacgatt actggtgaat ggacgaatcc attccctggc
     5761 agcagtttag ataaaagttc cttcagcggt ggtcaattat ttggaacgaa tccaggcggt
     5821 gaattccgtc cgaacggctt ccatgatgga ttagattttg gttcagttga tcatccagga
     5881 agtgagattc atgcggttca tggcggaaaa gtcgtgtacg ttggcaatcc tggtatttca
     5941 ggtttgggtg cgtgtgtgat cgtgattaat tacgatggct tgaatatggt gtatcaagaa
     6001 tttgcaaata gtacaggaaa ttctcgagtg aaagtaggcg atcaagtgaa agttggtcaa
     6061 gtaattggga tacgagatac agcacacttg catttaggat ttactcgaat ggattggcgt
     6121 caagcacaag gacatgcatt cattgatgat ggtacatgga tcgatccgtt accatttttg
     6181 aatagcagta aaaaatagat caggagaaaa aatatggaaa ataaaacgtt aaaaatcgtc
     6241 ttaacagctg caattagcgt tagtttaatc ggcaatattg cgttgttttg gcagctgaaa
     6301 gaggaacaag cagcaaatac ctataaaatt gaagaagtgg ctaaaaacgc gtctgagaag
     6361 ctcaaaaaaa attcctctga ggcacaggcg aagatcgaca agttaaatca aaccatcaat
     6421 gagaaaaacc aagaaatcga tcagctgaag caacaagatg gcacaaaagc aaaagaggaa
     6481 gtaactgaag cacaaagaaa gacggcagaa gagttcggtc aattggccat tgataaatca
     6541 ttaagcagaa atgaattaac ggaaaaacta aaagatgtcg caacccaaga agtgatcgac
     6601 aaattaagtc ctacagacga tgatcaccaa catgatgatt acggaagtta ctcctttaca
     6661 ttaggtgacg tgcaaactta cgctcaaaca agcagtgtaa aagaggaaca aaattttgtc
     6721 gtatttgttg attatacaat cggcaatccg caattcaaag atgtcaaacc acaaaaaata
     6781 aaaggtggat taactgtcac tgaaaaacaa gtagatggtc aatggaaagt catagacttt
     6841 agttatttca ctcgttagga ggaagaaaat gagtaagaaa aaaggagaaa gacaacgttt
     6901 caaaaaacga aaaagttatc ttagatggct gggaatcttt atgattctcg gctttttgat
     6961 tcttgctagt ccgatttata cgaatcagaa ggtagatata ccagatgagg taagcacgaa
     7021 cgccttttta aacacgaaag agctgacaat ggtttcaaaa gaaaaaggag cgaaccagca
     7081 attagttttt gaatttgcga tcgatgatga agatcaaagc ttgttaaaag aactggctaa
     7141 tcttaattat cgcgtagaag taaagacagc taaaggggat tatcaagcaa tacgagccaa
     7201 agtgattaag gtgtctgatg attattttgc agtgaagcta acgcatgtac cagaagaata
     7261 tatcgccatg cgtttaacca ttattcctga aaaaattgat ccaaaagtgg atatgcaaga
     7321 accacaagat ctgatttttt atattcacga agataaggtc aaagatcacg tgaaagacga
     7381 agattatgaa caacatgcga tcaattacaa agtgaaagga tacaagaaag aacaaaaagc
     7441 agctcaaaaa caaatggaat ctttccaagc aaccattgat ttgaatgaag aattagtgaa
     7501 gaagctaaaa gatcaattgc cttatcaagt cgcagatgat caggaaaata ctgaaaacaa
     7561 gattaatagc taccagcaag aaattgaaac atcgaaaacg caactgaaag atcaagaaga
     7621 gatcattcaa aaacttcaag aaaaaattga tcgtatgaca aaagaaaaga tttagaagga
     7681 caggtggagt gaaaaaatga agcgaacaaa cttggctgac aaagatactt tcgctgagca
     7741 gaaagtattg attaaagcct atctcaaagt tgtaaaagct aaagaaatat gtcgagaagt
     7801 gaatttatct aacacaacaa tatctgagtt gaagaatggt cgaaagaatt tagatacctt
     7861 aaaattcaga tcatttgaag ctctatatgt agctgctaaa aaatatttta cagctgataa
     7921 caaataaaaa acaggagtat tttatgtgaa aaaagtatat aaaaaatgct tatgaatcag
     7981 ctatatcacc ttaaccattt gttaatgaga tgggagaaaa cattaaccac gattctaacg
     8041 caaacatcaa gcacataaaa catttaacac tcctcctttc tggctgaaga tttcaaccaa
     8101 acaggaagac agcgtatcaa ttatagcata cactttttct taaattcatt tttcatatga
     8161 caaaatattt ccttctaatc gacaaagtta gaaggatttt ttattgtcta aatacacaaa
     8221 taaccttaat ttttaaagag cataaggaaa cgtgatatca ctttctcacg aaaggtgtta
     8281 ggtaggctgt gcctaccacg tttctaagaa agataaatga tatcaaaatt ttggatttgt
     8341 gtgtagattt gtgggtagga tgaaagcgaa tgtgggcagt aaaataagcg tttgtgtgta
     8401 gcaaaatcaa aaaatgtgta gggatatgtg tagctacaca tatccctaca cataataaat
     8461 ttggaggaaa atatggactt attaattaga aatattgaag aaaagtatat taataaaatt
     8521 gacaaacgtt gtgaagaact tacggtcaag actggcaaaa aatggagtcg aaatcaatac
     8581 ctaaaagttt tgatcgaaaa tgattttgat cacgctcttc tgaattataa aaaagaccaa
     8641 tttgatcggt tgttagaaaa atttgtggat attcaaactt ataatacgaa aactttagaa
     8701 gaatatattg caacaaataa tcaattaatt ggtttgttaa ttgaataata aaaatagtat
     8761 tgtgaattta taaaaggagg aaatcaattt tggcaaaagc aacaagaaaa catgtatatc
     8821 tttacgatat gcatatcgaa gtacttgatg aaataatttc tactcatgaa gatatatcta
     8881 attatagtga agcagtcaga catttgtgta tgatgtatga tccaaaaatc gaagaaaaaa
     8941 taaatccaat tcaaattaaa ttgaatgcaa tgggaaaaga aatttctatt ttaaccgaaa
     9001 tggtttcaga gtttgcggat cttcatttga aagatacagg aatactaatt ggtacaaatt
     9061 caactgttta tcaagaagca gaagaacgtg tggaaggaaa aattaaatcc aatcaaacca
     9121 aaaaatattc ttctaagtta aagaaaccag tgaatgaatc tgttcatacc agagtagatc
     9181 catttgatcc aacgaagatt ctaaaaagat aaaagtagaa ggagaacgtg atgaataaat
     9241 cgcctgcagt tattcttact tgtcaattta ccttgcccaa taaaaaatct ttttcaacat
     9301 acattgatta tatgacaaga gaaaaagcac tggaagaaat ggaacgacgt acgcccgaag
     9361 aagaacagga actgcaacga atcaagaatg ctttagagga tttttatatt cctgaaggag
     9421 aaactttttc ggaaagtaag acggataaag aattcagtga aacgtcgaat gaagctcaat
     9481 cgttgatgga acatggaatc aattttgaca agttagagga acaagatttt accaaatatc
     9541 tttcttatat gacccgtcac tatgcgttag aacaaaagaa agaactgacg caaagggaac
     9601 aaaaagaata ccaacggttg aaccaagcaa tgaaaaaata tcaaacagag ccacataaaa
     9661 aagcttcagg aaatcttcct ggagtttttt ctatggcttc agacgaagtg aaaggaagtg
     9721 atctgaagga gatcaaacaa atcttccaaa gaggacaaca aaaaggctca atcatttatc
     9781 aagatgttat ctctcacgac aattcgtatc ttgaaaaaat gggcttgtac gatcccaaaa
     9841 cagatacctt agatgaagaa ggtttgaaag cagctggaag aaaaatgatg gagacattat
     9901 tcgagaaaga acaattgaat gaaacaggtt actggatggc aacgattcac cgtaacacta
     9961 agcatatcca tattcatttt gcagttgttg aaaaagaaaa tacgcgtaaa ccgtatactg
    10021 agattgaaaa tggtgtgagt tatatcgtac cgaaggggaa gagaagacaa gcaacattag
    10081 acgcaatgaa aaccaattat gtacatgagt tagaacgttt ctcttatgaa aaggatcgaa
    10141 tgatcggtat ggagaaacga aatttattga cacgaaaaag tgatttgcgt aacaccttaa
    10201 caaaagtagt aaaagaacca gcacgttacg atcgacacgc catgaactta ttaaatgaag
    10261 tatataaaac cctacctgaa aaacgttcgg aatggaatta tggagatgaa aatcgaacca
    10321 agctttcacc atttacaagg ggaaaacttg atgagttaac caaatatgtt ttaacaaaag
    10381 aacctggata tcaagaatat atacagattt caaaagcatt gaaagaagaa gccaaaagcc
    10441 tttatgggga aagcaaaaga gaaacaaaga atgcagaaaa aaacgccctc tttgatttaa
    10501 aaaagcgcac aggaaatgcg attttaacag aactgaagag acaggatagt caaataaaac
    10561 cattaataga aagtgtcaat cagatgcaat ctatttacaa tgaacgatcc tttcgaacac
    10621 tcaaacagtt gccaacaaat gaatacaagt atagttatca agaattcgta aagcgtagga
    10681 aacaattcca acaaagagtt gtcacgcagc gaagcttgcg tcaattaaat cgaacaatta
    10741 atgcacatga agaaaaatac cacgcaagta aagcatatga agagcaacag cgaagaatcc
    10801 aaatggaaca agaaagacaa taggaggaag agaaatgaaa caatatttag atcaatggaa
    10861 agtcatagaa ggatcactaa aagaagaacg aatcgaacaa cttcctgatt gtttagaaaa
    10921 agagcatttg tttcagataa gcgaaatgtt gagaaacgaa cagtttgatc caaatcaatt
    10981 tttagttgtt gagtacccag ctactggtgt gtattgttgt aatcatgtga agggtgaaaa
    11041 atattttatt attcaagaat acgaaggtaa gttagcgcct tattatacta cttgggaaat
    11101 aaatgaagag ggaatcaata atttcccatg tgaaagcatt gaagagtcta tttctctcac
    11161 ggaatgttaa ataaatagag acgtaaaaga gtcctgaacg tgattgtcca ggactctttt
    11221 tcaatgaatt gttttccgcc aattcactga gtggtgcgat tcaattttat tatatcaaaa
    11281 gaaagtgaga ttccaaagtg aagggaggaa gaagaaatga ctcagacaac gattggtgtt
    11341 gtggttgaaa aaagcaggga taatctcgtt tttgtgacag aaattcaaac aggtagagct
    11401 tttgtagtca cagacaaagc tgcaaaagcg tatcaaaatg gcaatatttt aacgttaaat
    11461 ctgactacga agatgttcgt tgatgcagta gaaaattatc catttgttta gacaaacgat
    11521 attttacaag gaggaaacgg acatggcaga agaaaaagaa ccactagata atagtcggtt
    11581 gggaaagtcc aaaagaaaat tagtacggtt gcaaaacgaa ttaaataatc aatttcaaaa
    11641 gctatttgat caccaaaaat tgacaaatgg gcaaccaatg aatgacaaac gaaatggtcg
    11701 ttcatggttt aaccagcaag aaaaaataga aaataaaata caaagtttga gagaagagat
    11761 caagcaacaa gaaaaacagg tagaaaaact tgaaagacaa gaagagctaa aggaaatggg
    11821 ctataacaag tacggcggac tggatatgac gatcgataat attccaagaa tcaaagaaga
    11881 aatcgaacgc tttgaaaaag gtgaatcgac tttttcagcc gccacgatcc gaaaatatca
    11941 acggaagttg gaaacattag aacagctgaa agaaaaatca gaaaaaggaa aagaaaatat
    12001 cctccctgaa gtacaagcga tcattgacag cggacgagtg acgcaatgga aaaaaaatcc
    12061 aaccatttat tttttgaaag gctatcgaaa agttgcttta gaactgaatg aaaacggggg
    12121 atttgaggaa tcaaaaaaat accaagccac gtcggaagag gaaaaagcag ctgttcgtga
    12181 attacttgaa gaggctgcac caactgattc tctgaaggag aaagaaaaag atcatttcta
    12241 tcgagtagaa ttcaacgaaa atgatccaga aaaaggattg aaaagttatg gtggggagat
    12301 cgtaacatta gaattgatcg atcaacttaa aacgttggat aaccaatacg ctgcagaagc
    12361 aggttattat aaattctatt ttgaagaagt gaagaacgga gaagtagtag atcagatccg
    12421 aatggatcta ggggatggcg tcaacagtaa tcaccccatc tatttagagt tagcaaaatt
    12481 gtgcgaacaa gtacctgaga aggaacaaaa acaatcggtc aaaaatgaac ctgtttcgaa
    12541 agaacaaatg cagtcgaaag aaacaaaaac aaaacaaaag ggctatcaaa aacgaacggc
    12601 agaagagatc aaacaagaag ttaaatccct ttcgcaacag gcactggatg cggtgaaaaa
    12661 gcatacccat tcttctgaag acgtcaaaga acttttgaac tttatgtctc gttttccaga
    12721 acgatccttt agaaatcaat tattgattga ggaacaattt ccaggtgcaa cggcttgttt
    12781 aggtcgtgcc gcgttgaaaa aagaaggaat ctatatcaaa aaaggggaac aagggaacaa
    12841 gatctttgtc agaaaaacgg tcaaaggatt ttatgagaaa ggacgtggct ttgttcgaga
    12901 aacagaagct acaccagaag ataaaaaacg aatcgaaagt ggtcaaatcg aagtgatcaa
    12961 aaaaccttac tacacgattg aaaaagtgtt tgatatcaca caaacacagt taaaacctga
    13021 agactatccg aaaatctttc cgaaccgtgt ctttgatttt caattggata aaaaaggaca
    13081 gtcagaactt caagctggga ttcaagcggt agccaacaat attggaatac aaattcgaga
    13141 tatgacagaa agtgaagtct atcaaagaga attaggacaa gcacg
//
LOCUS       DADLIO010000071        12916 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.074, whole genome shotgun sequence.
ACCESSION   DADLIO010000071 DADLIO010000000
VERSION     DADLIO010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12916)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12916)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12916
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.074"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            133..3660
                     /locus_tag="JOX41_002272"
     CDS             133..3660
                     /locus_tag="JOX41_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAY6449983.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3657..7379
                     /gene="addA"
                     /locus_tag="JOX41_002273"
     CDS             3657..7379
                     /gene="addA"
                     /locus_tag="JOX41_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HAY6449984.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7448..7789
                     /locus_tag="JOX41_002274"
     CDS             7448..7789
                     /locus_tag="JOX41_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAY6449985.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8098..9141
                     /gene="pheS"
                     /locus_tag="JOX41_002275"
     CDS             8098..9141
                     /gene="pheS"
                     /locus_tag="JOX41_002275"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HAY6449986.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9146..11566
                     /locus_tag="JOX41_002276"
     CDS             9146..11566
                     /locus_tag="JOX41_002276"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HAY6449987.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="JOX41_002277"
     CDS             complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="JOX41_002277"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HAY6449988.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
BASE COUNT         4387 a         2244 c         2739 g         3546 t
ORIGIN      
        1 tttttgcgta tacttaaaaa agtagaaata tcagaacctt aaaaggatat aatttgaaga
       61 atatagaaca aatgttcagt attttttgat ataataaagg agcaccgtat catgtgttga
      121 aggaggaaaa gcatgtcttt acaatttatt cttggaaacg ggaaaaaaga tcaccgtcaa
      181 gtcttgatcg acgaagcatc cgcttggctc gaccaggatg caagtaacca agtatttttc
      241 cttgttccca actacagcaa attcgaacag gaacaagaaa ttttagcgga gatgcgaaga
      301 agaagcggaa aaaaaacttt cagcacaaca aacgttcaag tatttagttt ttatcgtctg
      361 gcttggtatt tgctgcaaca gacaactctt cttacaggaa atgaattatc agaatcagga
      421 tctgcaatga tcttgcgaca gattttagaa aaaaatgagg aagaattaac aatctttcgc
      481 ggagaaatca ataaaagagg gtttattcgt caattacaag aactctacag tgaattgcgt
      541 acaggaaata ttcaaccaga agacctgatg cttttatttg gtgattcacc taatgcagaa
      601 gaccagcaac ttaaaatgaa agacttgaag ctgatttttt cagcttatga cagcgaattg
      661 actcaacgtg cactaacaaa tgaagatgca ctatctatac tagcaaatta tatgcagaca
      721 caagatttca acaacgtcaa atttattgtc agtggttttt ctcgaatcaa tggtcaagag
      781 tatcaattac tgcaggcaat gatggaaaag gggcaattgg ttgtcgattt attgctggat
      841 cgtccttata cagcggatct tccagaagta cttacgctct ttcatgagac tggaaagctt
      901 tatttccgtc tttttcaaag tgcaagagaa cggaaagtcc ctatattagt ggaccgattt
      961 gcaccagagc agactcgtcc gacagagctt caactgctgc aaacaatgtg ggaagagaca
     1021 tctagccaaa agaaagcggc agtacacaaa atagggggac aagagcatct ccatttgtgg
     1081 gaagctgaaa atccaactga agaagtccga caattagctg ttgaaatcag acgactagtc
     1141 agtgaagaaa actaccgtta tcgtgatatc caagtgctga caaaaaatat gtctttatat
     1201 ggaaatatcc ttcggccgat ctttcaagaa atggcaattc ctttttatat cgatgaagaa
     1261 caaatgatgg aaaatcatcc gctgatcgaa tggatcaaca gtctgttcgc tcttgaccgc
     1321 tattcttatc ggctaagtga tattatgcgt tttttcaaaa ctgaattatt tctgtcgacg
     1381 gaagcagaaa ccgaacttga tgaatggaaa caagagcgag atgaattcag gaaaaaactg
     1441 gacatcactg aaaatgtagc acttgcttac aattatcaag gaacttattg gactcgtgaa
     1501 aaagactggc agtttgtggc gtatgatttt gaagcagaac agattgaaga cgtacagtat
     1561 ttggaagaac agtcaaatac gattagacga ttatttcaga aagctgtacc agtatttttg
     1621 aaaaaaataa agaaaagcaa aacaggacaa gaggccgcaa atgtttttta tcaatttttg
     1681 atccaaagtg gcgtacagca acaattattg ttttggcgta atcaggaagt agacagagga
     1741 aacttagaag cggcaagaaa ccatgagcag acatggggag cgctgattga tctgttggat
     1801 gaatatgtag taatttatgg tgaatcggct tttgactggt cactgttcca agaaatcatt
     1861 acaagtggtc tagaaaatct aagttatggt aaaatcccta ccgcaatcga ccaagtgcga
     1921 atcaatcgtt tggaattagt tcgaccaaat caagctgccg tcacttttgc attagggttg
     1981 aatgatcaag tgtttccaga ccgaaaagag acaaaaggat tgttgtccag tgaagaacga
     2041 gaagtattaa atcaggcctt gccagatgga cagtttttat tcgacccatc aaaggaaagt
     2101 atctcttttg agcctttcca agcctatctt gtttttcttt ccggaacaga tcgattatat
     2161 cttagttatg cacaaagcta tgacacagat ggttcgctga agatgtctcc ttatttgcgt
     2221 agaatcacag aatatttatc tgttcccgtc gagagaaaag agcatttgac gatcgaaagc
     2281 gaccctaatt gttatgtagg gacttacaga agcggaatca atacagtcaa taggatttat
     2341 cgattagctt tagatgaaaa aaaacctgta ccaaagcact ggcaaaagct caaagaatta
     2401 gtactgaatt cgtcatggcg aaattttgct ttacagattt ttgaaagtca ggaacattta
     2461 aatgttcctg tttcgatgcc agaaaaaatg gcggaagagc tttatggaaa agagatttat
     2521 acttcaattt cacgtatgga gaatttttat aattgtgaat acaaatactt catgcaattt
     2581 ggtttgaaat tgaaagaacg aactgtttat ggtctaactc cagcagcaac tggtgatttt
     2641 tatcatgaat cattggatcg tttcttcaag ctactgtttt caaaccaatt atccttagtg
     2701 aatatgtccg atgcgcagcg tagagacttt actgaaaaag tgctgcagga agtattcgga
     2761 gaacttcggt ttgagatatt ggatagttct gcaagaatga actatatccg ctaccagtta
     2821 ggacagacga ttcaaaaagt gacatgggct ttgcaaaaac agagcaaaaa tacaggcatg
     2881 catcctcttc agacagagat tctatttggt cagattgctg gagcaaaagg tatcacaggt
     2941 ctggaattac cgttgagtaa tggtggaaaa ctccatgttc gagggaaaat cgatcgaatc
     3001 gatgtagctt ctgaacaaga agatacttgg ctaagcgtcg ttgattacaa atctagcgga
     3061 cgttcattcg atgtcacaga agcttattat ggcatggcta tgcaattatt gacgtatctg
     3121 gacgtagcat tgatggatgc ggtacgtttg actggaaagg cggctgttaa accagcagga
     3181 tcatattatt tacatgttca taatcctgta ttgacggaga cagatgatgt agagaagaat
     3241 acattgaaaa aatttagtta tgatggcgtt tttgtcgatg atcccgctct tttagaagta
     3301 ctagatcatt cactggaagc aaaagaacaa tcactgatct atccagtgaa aaaaaatgcg
     3361 aaagatgaat accaaaaagg tagtttcagt aaagacaaat ttttcacgga agaagaactg
     3421 caactattca tggcgcataa tcgggaaaat atgcggttag ctggagatgc gattacttcc
     3481 ggagaaatca aactaaatcc agcttataaa gataaacagc ggattgcctg cgaattttgt
     3541 ccattcagaa gcatctgtac gtttgatgtg atgctgaaag aaaataatta ccaccgtctg
     3601 gagaaaatag ataaggaaga agcactgcgt agaatattga aaaggagtga agaagagtga
     3661 atcaaattcc tttaaaaccg caaaatgaac gattcacaga tgatcagtgg caagcgattt
     3721 ttgatcaagg agataatcta ttagtctctg cgtctgccgg atcaggtaaa actacagtgc
     3781 ttgttcgaag agtgattgaa aaactaaaaa tgggttttga tatcgatgaa ttattgattg
     3841 tgacatttac tgaagctgcc gcaagagaaa tgaaagaaag aattcaagag gcattacaag
     3901 aatccgtcaa tagcgaaagt gaccctgtac gtagacagca ttttactaag cagttagttt
     3961 tattgcccac agcgaatatc tcaaccttac atgctttttg cctgacagtt attcgacgtt
     4021 attattactt aattgatatt gatccagtct ttcgcatgtt aacagatgaa acagaaacga
     4081 tcttgatgaa ggaggatgtg tgggacgagc tgagagaagc actttatgca gaaaatgatg
     4141 aacgattttt ccaattaaca atgaattttt ctaatgatcg ttcagatgac ggcttgacga
     4201 atctggtgtt ttctctttat gagtttgccc gtgccaaccc tgacccccaa aaatggctag
     4261 aacagttaag cgataattat cgtttgcctg aggggctagc gaaatctcga ttatatcaaa
     4321 aacaaatccg tcctttagtt ttggcagata tataccaatg tgtacagtta tatgaacaga
     4381 tgactcagtt agcacaaggt gaaggattag aaaaaatgca tgagcaagta gctggagaac
     4441 aacagcagat caagaatatc tatgaagcgt tctcgcaaga tcggttagaa gaagcttatg
     4501 ctggtttgga acaactaact ttttcaactt ttaagagcag tcggaaagca gaattgaaag
     4561 aaatttccaa tgaagtcaag ggcatgaggg ataaagcaaa aaaactgatt cagcagataa
     4621 gtaaaagtta ttttcctgtt tccccaagcc aaatggaaga attaacggac aaagcactac
     4681 cgttagtcga agaaatgaca aaagtcacgc aaagcttcat ggacggtttc agtatgcgta
     4741 aacgggaaaa aggtgtgctg gatttcaatg atctggaaca tttagcgttg cagattctca
     4801 cagaaaaaac gaaagatgta tggctgccaa gtgaagcttc aaaacattat cgaaaaaaat
     4861 tcaaagaagt aatggtagat gaatatcaag acgtgaacca attacaagaa gccattttat
     4921 actggctaag agaacccgat gatacaaaag gaaatatgtt catggttggg gatgtcaaac
     4981 aatccatcta ttctttccgt ttagcagatc ctagtttatt tatcgggaaa tacgagaatt
     5041 tctcaaagaa agaaggcgga cgtcgaatcg ttttggctga gaacttccgc tctagaaaag
     5101 aagtcctttc ttttacgaat cttatttttg aacaactaat ggatccagca gtgggtcaaa
     5161 tcaattatga cgaagcagcc aaactgatcc aaggattttc agactttcca gagaatgaac
     5221 agtttgagcc ggaaatcatg atctatgaaa aagaacagga agaatcagag attgagattc
     5281 cgacggatga tatactggaa gacaaaacag aaggcgaact ttttatgaca ggactaaaaa
     5341 ttcgtcaatt aattgattcc tcctttatga tttatgataa aaaatcaaaa aaaagtcgtc
     5401 cgatagagta caaagacatt gttctcttga cacctacaaa gaagaacaac ttaacgattt
     5461 tagagatttt caaaacattg gatattccat tagagatgaa tgatgctcaa aactattttc
     5521 aagcgacaga aattcgcacg atgatctcgc tgctacaatt aatcgataat ccctatcaag
     5581 atattccgct tgcggctgta ttgcgctcac cgatcgtggg tctgattgaa ccagaattag
     5641 ccagcattcg attagctaac cgtgcacata cttactatga tgctgtgctt gcttatcaag
     5701 catcaaacga agatgaatta gcagctaagc tggaacattt tggcaagcaa ctagagcatt
     5761 ggcgagaact tgctcgccgt tcttcgatca ctgacttgtt atgggatatc tattatgaga
     5821 cgggatatct agagtatgtg gtcggtctgc cagcaggggc acagagacaa gccaatcttt
     5881 atgcattggt tgatcgtgcc aaagcttacg agcaaagttc tttcagagga ttataccagt
     5941 tcgtgcgttt cattgaaaaa atgcaagaaa aagataaaga cttagcagaa ccagtcattt
     6001 caatagaaga taatgctgtt cgcgttatga cgatccatgc aagtaaaggc ttggaattcc
     6061 cagttgtatt tttgttagat atgacaaagg agttcaactt acaagacttg cgcaatcggt
     6121 atgcttttga agaaaaactt ggagcaggaa ttcgctatat ggatcctgaa acacgagtgt
     6181 tatatgatac gttaccgttt caagccatca aattggcaaa gcaaaacaaa ttgttgtcgg
     6241 aagaaatgcg taaattgtat gtaggattga ctcgggcaga acaaaagctt ttcattgtcg
     6301 gttcctataa aaataaagag caaatgatcc aaacgtggtc tgaagcagct gatcatgagg
     6361 agttagtttt tgatcctgcg ctacgtttga agggcagaag cagcttgatg aattggattg
     6421 gttacggatt gatccgtcat cctgaaatgc agaaatactt agaggaagaa atttcgactt
     6481 ctcttcttca acattcaaat gcacagtttt ctatttcatg gatgaatcag caatcgatca
     6541 ttgaacaaag acagttgctt gctgaaaaag aactggttaa cttagatcag cagatgaaag
     6601 aagatgaaac tttattagca gattcgttac aaaaacgtct ggcatatgaa tatccttatc
     6661 aagcttcttc acaaaccaca agttatcaat ctgtatctga aatcaaacga ttattcgaag
     6721 atccagatga tacacaagaa tcacgtttga ctctggaaag cagtcagaac aaagcagcat
     6781 cccgtcaatt tcgttatacg caagaacaac tagcagaacc aaaatttttg caaaaagatc
     6841 ggcaagtgtc agcagctgct gttggaactg ctacgcatgc tttgttacaa ttactgccat
     6901 tagagatgcc aactacagag agtatccatc aaaaattaca ggaattggta aggaaacggt
     6961 tagtagacga aaaagtcgcg aaaaaagtag atgtttcttc tattatatgg ttctttcaaa
     7021 cagaacttgg tcaacagctg attgccaaca aagaaaacgt aaaacgagaa caaccttttt
     7081 ccatgctgct tcctgctgac gaagtatttc aagactatcc aaatcaagaa gatgaactat
     7141 taatccacgg aatcgtcgat ggatacctag aagaaaaaga tcatctcaat atctatgatt
     7201 ttaaaacaga ttttatttta catccggatg atccagcaga aatagatgca atcgtccaaa
     7261 aatatcaagg acagctaaga ctttaccaac aagcaatgtc agaagctttg aataagccag
     7321 tagaaaatgt tttcctaatt ttgcttcgag tgaaacaaat tataaacatt aacaaataat
     7381 tataattgag caaacttgac ttatgttttg taaggattat gctatactct gggaagaggt
     7441 gagtatgatg gagctaacac agacagaatt cgttttatgc cctaaatttg aaaaaacatt
     7501 ctctatttta ggaaaaaaat ggaacggatt gattatcgat gtactactcg aaaacggtcc
     7561 gcaacgcttt gttgagcttg cggcaaaaat cccgatggtc agtgatcgag tattagtcga
     7621 acgcttgaag gaattagaaa aagaaggaat agtcactcga aactttgcct gtagcgaaaa
     7681 gagccgttca gaatatctct tgactgaaaa aggagcagac ttgcaaaaag cgatgcgtca
     7741 aatacaagtt tggagcgaaa aatggatcac agaggaagaa tgcggttgat tttgtaaaaa
     7801 aaatcttgta aactatagtc catacgaata agtaaagaac gatgacgaaa aagagtagtt
     7861 tggctaaacc agttcaggga gatctgtcgc agactgaaag cagatcctgt gtttgaaaaa
     7921 tgaagttcac tttccgagtt cgtctgataa aatcagaccg gcaattgtcg ttaacgaagt
     7981 aagagtgcgg tgtaagtcat ttatccgcaa attaggatgg taacgcgaag acctcgttcc
     8041 ttaacaggaa tgaggtcttt ttgttttgta tttggaattt aaaggaggaa caagcacatg
     8101 tctctacaag cacaattaga gagcttgaaa gaagcaacgc tcgtcaaaat cacagcggca
     8161 caagatttaa atgaattaaa tcaaatacgt gttgaaacgt taggaaaaaa aggaccgatc
     8221 acagaagtat tacgtgggat gaaagatcta agtccagaag agcgaccaaa agtcggaagt
     8281 ttcgcaaatg agatccgaga tcttttgaca gaagagatcg agcgaaaaaa acaagtatta
     8341 gaagaagaag cgttaaatgc agctttggca aaagaaacaa tagacgtgac actacctggt
     8401 agaaaagtaa aacatggtac acgtcatatc gtgacacaaa tcatggaaga aattgaagat
     8461 atttttgtgg gtatgggcta tcagatcgta gaaggatatg aagtagaatc tgatcattac
     8521 aatttcgaac ggatgaatct gccaaaagat catccagcaa gggacatgca agatactttc
     8581 tatatttcag acgagatatt gattcggaca catacttcac cagtccaagc acggacaatg
     8641 gaaaaacatg atttctctaa gggtgctcta cgaatgatct cgccagggaa agtcttccgc
     8701 agagatacag atgatgcgac ccacagtcat cagttccatc aaattgaagg gctagttgtt
     8761 gataaaaaca tcacaatggg cgaccttaaa ggaacattag aagtcgtaat gaaaaaaatg
     8821 tttggggaag atcgtgaaat tcgtttgcgt ccaagttatt tcccatttac ggaaccatca
     8881 gtagaagtag atgtcagctg tttcaaatgt ggtggtgccg gttgtaacgt atgtaaatac
     8941 actggatgga tcgaaatttt aggagctggc atggtacacc cgaatgtgtt gaagatgtca
     9001 ggaatcgatc cagaagaata ttcaggcttt gctttcggcc ttggaccaga ccgcgtagct
     9061 atgttgcggt atggagtgaa tgatatccgt aatttctatc aaaatgactt acgtttctta
     9121 agtcagttca agggggagta agaaaatgtt agtttcatat aaatggctca atcgttatgt
     9181 agatttatcg aatgtaacac caaaagaatt agcggataag atgtctgtga caggaatcga
     9241 agtagaggga gtaacggttc cagaagaagg cttgaaaaaa atcgttgtcg gtgaagtcaa
     9301 ggaatgcgta ccacatccag attctgatca cctttctatt tgtcaagtcg atattggcga
     9361 agacgaactg tctcaaatcg tttgtggagc gcctaatgtg aaggttggaa tcaaagtgat
     9421 tgttgcactt cctaactcac gtatcgctgg taatgtaaaa atcaaaaaag gaaaaatgcg
     9481 tggccaagta tcaaatggca tgatttgctc attacaagaa attggctatt cagatagtgt
     9541 tataccgaaa gaatacgctg aaggtatcta ttatatgcca caagaagctg taaatggcga
     9601 tccagttttt ccttatttgg atatggatga ttcgattatt gaattatcta tcacaccgaa
     9661 tcgtgcggat gcattgtcaa tgcgtggcgt agcttatgaa gttggggcaa tttatcgtca
     9721 gactcctaca ttcgatgacg aaaagctggt agaatcctca cgtcctgcta gcgataaaat
     9781 tcaagtggaa gttgaagata aagaagcagt tcctgcttat caaatcagaa tcattgaagg
     9841 agtaagaatc cagccaagtc ctcaatggct gcaaaatctt ttgatgaacg aaggcattcg
     9901 tccaatcaac aatgtagtag atgtgacgaa ctatattttg cttttattcg gacaaccact
     9961 acatgcattt gactacgaca aattgaaatc aaaagagatc tttgtccgcc gtgcaaaaga
    10021 aaatgaaaca ttagtaacac tagatggaga atctcgggaa ttgacaactg acaatctcgt
    10081 cattactaac ggcaaagaac cagttgcttt agctggtgtc atgggagggt tagactcaga
    10141 gatcacgaat gaaacaacaa cagttgcact agaatctgct ttatttgatc caatttcgat
    10201 tcgtcgtaca gcaaaacaat ttaatttgcg tagtgaatcc tctgcacgtt ttgaaaaagg
    10261 aatcaaccat gcgactgttg gagaagccag tgaggttgct gcagcaatga tcgtttctct
    10321 tgcgggtggg gaagttctac aaggcgcggt caaaggctca gagatcaaag cagaagacgt
    10381 atcagtgaag atttcacttg aacgcatcaa tcaatattta ggaacatctc ttgtcgttaa
    10441 agaagtaaat gagatttttg aagcacttgg atttagctat gaagaaaagg agtatgttta
    10501 ttccgtagta gtaccaccaa gacgctggga tatccaaatc gaagcagata ttatcgaaga
    10561 agttgctcgt atttatggat acgaccagtt gccatctaca cttccaagtg gagaaacggt
    10621 tgctggaagc ttgtcaaaag aacaagaaac tactcgtaaa attcgtacaa tctttgaagg
    10681 aagcggattg agcgaagcaa tcagttatgc attgacaaca gaagaaaaat caagacagtt
    10741 tgttataaat gaaagtaata ttacacgttt ggactggcca atgagcgaag aacgttctgt
    10801 attacgaatg aatttgatca gcggactatt agatgatatc agttataaca ctgcccgaaa
    10861 aaatacagag attgctttat atgaaattgg tcgggtgttc ttccaagaaa atgatccacg
    10921 tacacatctg ccgcaagaag taaaacatgc agcaatcgct atttctggta tttgggaaga
    10981 aaaagattgg cagacgaaag ctcaaaatgt agactttttc accatcaagg gtcttttaga
    11041 aaacttattt gaacaactag gcatcactga agatgtccat tatcaaacag tgacagaaat
    11101 gaaggaaatg catcctggaa gaactgctgc gatttacctt ggcgaaaaat ttattggttt
    11161 tgtcggtcaa gtgcatccaa cgattacaaa aagttatgat attccagaaa catatgttgc
    11221 tgagtttgat ttatctgcta tagtggaagc tgctcaaaaa gggatcgttt tcgaagcagt
    11281 gacaaaattc ccagcagtca gccgggacat cgctttgctt gtaaaagaaa ctgtgacaaa
    11341 tcaggaatta acagaagtta tccgttctgc tgccggaaga tttttaacag atatccaatt
    11401 atttgatgtc tatcaaggag aaaacattga aaaaggacat aaatccatgg cgtatagcct
    11461 gacattcgtc aacccagaag caacattgac agatgaagaa atcaataaag caatggaaaa
    11521 agtcgaaaaa gcgttggtag aaaacctaga ggcaagtatt cgctaagaag gaaaatatag
    11581 taagtaacga tcaagtagct tttgaagacc atacatttga aaaaaagatg tgacacaact
    11641 tcgtcacatc tctttttttg attttaaaaa aggaatagca cagagacgag ataaaaaaac
    11701 aggcctttac agcctgcttt tttagagtaa atgaattaat ggaagtaatt gattcccatt
    11761 gctgatttta cttcagaaag tgtttgtgca gctactttag cagcttcttc actaccttta
    11821 cgtaagattt ccataacagc tgaaggatct ttttccaatt cttctcggcg cgcacggatc
    11881 ggtgcaaatt cagcttccaa tacatcaatg aggtatcgtt tgatctttac atcaccaagt
    11941 ccgccgcggc ggtaatgagc tttcatttct tcaattgctt ctttatctgt tccgaataca
    12001 tccaagtagg tgaagaccat attcccttct acttgtccag gatcttgtac atggatgtgg
    12061 tttggatcag tatacatact catgactttt ttctgtaaga catcggcagg atcggagata
    12121 taaataccgt ttcctaacga tttactcatt ttgccatttc catcgattcc aggtaatcta
    12181 cccattcctt ttggtgggaa tacgcctttt ggttccacca agacttcacc atatgtatga
    12241 ttgaagcttt gtacgatttc ctgtgtctgc tctagcattg gtttttgatc ctcaccaaca
    12301 ggtacaagat tcgctttgaa tgcagtgata tctgctgctt gagaaacagg atagataaag
    12361 aatcctgtag gcacgctttc accgaatttt ttttgttcga tttctgtttt gacagtcgga
    12421 ttgcgccgaa cgcgtcctac gctgactaag ttcaaataat acatggttaa ttcagctaat
    12481 tccggaattt gtgattggat aaataaagta gattttgcag gatctaatcc cacggctaaa
    12541 tagtctaaag caacttgcaa gacatttgat gaaaccttct caggattttt agcattatct
    12601 gtcagtgctt gcatgtcagc aatcatgaca aacagttggt tgtcttcatc tgcctgcata
    12661 gccactcggg tttttagaga accgacgtaa tgccctaaat gcagcttccc agttggtcga
    12721 tctcccgtta aaataatatt tttcaaaaaa gacacctctt tacgatttgt aagtctgagc
    12781 acttaatatc ttaccgtttt tcctgaaaag aaacaacagt tcctaaggaa aaaacaagga
    12841 aagaggataa aataactaat agattagaaa tggaagaaat atttatggga gaataaacgt
    12901 tctaagaaac tttaca
//
LOCUS       DADLIO010000072        12747 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.075, whole genome shotgun sequence.
ACCESSION   DADLIO010000072 DADLIO010000000
VERSION     DADLIO010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12747
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.075"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(86..265)
                     /gene="rpmF"
                     /locus_tag="JOX41_002278"
     CDS             complement(86..265)
                     /gene="rpmF"
                     /locus_tag="JOX41_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HAY6449989.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(323..892)
                     /locus_tag="JOX41_002279"
     CDS             complement(323..892)
                     /locus_tag="JOX41_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HAY6449990.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1078..1980
                     /locus_tag="JOX41_002280"
     CDS             1078..1980
                     /locus_tag="JOX41_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAY6449991.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="JOX41_002281"
     CDS             complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="JOX41_002281"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HAY6449992.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="JOX41_002282"
     CDS             complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="JOX41_002282"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HAY6449993.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5003..8323)
                     /gene="dnaE"
                     /locus_tag="JOX41_002283"
     CDS             complement(5003..8323)
                     /gene="dnaE"
                     /locus_tag="JOX41_002283"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HAY6449994.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSK
                     SIKGQLIYLLGEDNVVFK"
     gene            8554..8739
                     /locus_tag="JOX41_002284"
     CDS             8554..8739
                     /locus_tag="JOX41_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HAY6449995.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8801..9997)
                     /locus_tag="JOX41_002285"
     CDS             complement(8801..9997)
                     /locus_tag="JOX41_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAY6449996.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10167..11603)
                     /locus_tag="JOX41_002286"
     CDS             complement(10167..11603)
                     /locus_tag="JOX41_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAY6449997.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11896..12705
                     /locus_tag="JOX41_002287"
     CDS             11896..12705
                     /locus_tag="JOX41_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAY6449998.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3804 a         2675 c         2250 g         4018 t
ORIGIN      
        1 tattttttat ttaccgacta caaaaaaata aacctcaagg ctccatggtt agccttgagg
       61 ttttacattt tctaattaaa atgtattaag cttcttttga cattacgtcc ttaccatcat
      121 agtaaccaca atttgcacat acgtgatggc tttttttcat ttcaccacag tttggacatt
      181 cgtttaaccc tttgattgtc aatttgtagt gtgtacgacg ttttgctttt ttagcttttg
      241 atgttcttct agctggtact gccattttgc tacacctcct tgtaaagtct tgtatctaaa
      301 ttagacacaa tatattccaa tcttacttgt tatcgtcgtc ttttgattta gaatcaaaaa
      361 gttcagatag ttttgcaaga cgaggatcaa ttttattctc ggcttcttcc atttttctgc
      421 gctggtattc ttcttcggaa acaacttccc aatcattgcc ttttggaagt tctgttgctg
      481 cttcctcttc ttttgtcaat acccgcattg gaatcgccaa taagatgttg tcttcaatcg
      541 actctgctaa attcaataat ggaccttcaa ttagcaaaat ctcatctgca gacatttgtt
      601 catctctact ttggaattgt tcttctgtca tgaatacttc gtctacagaa aaatccatgg
      661 gcagttcaac aggttctagt gaacgtgttg aaggaactgt caaagtcgtc tgcacagtgt
      721 aatgaacgat atagcctttc ttatcaactg agaccaaacc ttcgacttcc actggcgcaa
      781 catcaagtat taaattgtct cgcttcatga gagcggcttt caagtcgagc gtctcatgaa
      841 aagttaacgg tgtctcctgg tattttctca attccaataa agaccatttc atttttcatc
      901 actcctaagc aacaaaagca attatacagg gcaaaaagca tgttgtcaat gaaattttct
      961 tgacaccttg cagttcataa aaaaacagaa aaatctttat tagaaagcct ctgtttgcta
     1021 tcatcctcag aatcatttac aataatcatt attccattaa aggagcggat gatcttcatg
     1081 aacacgaaag atatcgaata ctatgtccaa atcgtcaaac aaaaaaattt tacgaaagtg
     1141 gctaattatt tccgtgtgag ccaacctact attacatatg cattacaacg tcttgaaaaa
     1201 gagtttgaca ccgtacttat tacaagagat cgatcgcatc acgaattaat cgtcacgcct
     1261 tctggaaagc agctgtttct ccatgcacaa accattctcc aagagatttc tactgcaaga
     1321 gctgaaatca ctcagttgca aaagaaaaag cttcgttttg gcatgcctcc tattatcggc
     1381 aatgaatact ttcctaaact gtcaagttac tttatcaagc atgaattgat gaatcaaatt
     1441 gagattaccg atggaggctc tcgggactta tacgggatga tccgacaagg gaggatcgat
     1501 ttagctgtat taggctcaac acagccaatc gtggatcaat atttagaaac agagttactt
     1561 ttggacaaac gtttcatgat cgtcgtgcca cctacacatc ctctttccaa gcaggatact
     1621 gtctctttca aagatatagc agatgaacag tttgtactat tgaacgaaca ttatgtccac
     1681 cccgcagcat tcactaagct ttctaaacaa acacatactc atccaaaagt tgtttatcaa
     1741 agcaatgact tgacgatttt aaagagtatg gtccgagaaa atgtgggtat cggttttttg
     1801 gcagagattg ctgtccatcc tgaagatcat ttagtttgcc tccctctttc agatgaagtt
     1861 cagcctcgct tcttgatttc attggcaaaa cgaacacagc agatcgtcac gcctcttcaa
     1921 gaacaagtag tccaagttat ccatgaattc gttacagcac aaaaaaacag ctcttcgtaa
     1981 aagaagagct gtttttattt tttattaagc taaattagat agctgttgtt tcgccacggt
     2041 aaacgatgcc gcgacgtgaa tcaacggtaa tcaattcacc ttctgtaatt gttgttgttg
     2101 cgcctttagc accaacgatt acaggaatat cttgtgcaat tcctacaact gcagcgtgag
     2161 aagtcaatcc gccttcttca acgataacag cagctgcttt ttcgattgca ggcatatatt
     2221 ctttgtcagt tgatggtaca actagaacca ttccgtcttt tgcttttttt acagcttctt
     2281 cagcagatga agcaataact gcatttgcaa cgacagattt ttgtccaacg ccttgagctt
     2341 ctaataattt agaaccaatc atttgaattt tcatcacgtt agttgttccg cgttcaccaa
     2401 ctggtacacc agcagtgatc aagattaaat cgccttctga tgcgaaacct aattcaacag
     2461 cttttttagc tgctagttca aacatttcat cagttgttga tggtttttca gcaactgttg
     2521 ggtaaacgcc ccagtttaac atcaaaccac gttttgtgcg ttcgtcaaaa gtaacagcca
     2581 agatatctgc atctggacga tattttgaaa tcatttttgc agtgtatcct gattcagttg
     2641 cagcaacgat tgttttcacg cctagatttt ttgcagcacg agctacagat aaaccgattg
     2701 tttcagttac atctgtttta tcgaattcgt tcaattggaa tgtacctaat tctgataatg
     2761 cattttcagc ttcttggtcg atacgtgcca ttgttgaaac agcttcaact gggtagtccc
     2821 cgtttgcaga ttcaccagat agcattgttg catctgtgcc atcaaataca gcgttagcaa
     2881 cgtcagaagc ttccgcacgt gttggacgtg ggttttcttg cattgattct aacatttgtg
     2941 tagcagtgat aactgggata ccagcagcat tacatttttt gataatgcgt ttttgaacca
     3001 ttggtactag ttcagctggg atttcaacac ccatatctcc gcgggcaatc ataacaccgt
     3061 cagaaacttt gatgatttcg tcaatgttgt cgataccttc ttgagattcg attttaggga
     3121 agatttgaac atgagtcatg tctttttctt ctaagatttc gcggatatct agaacgtctt
     3181 gtgctttacg tacaaaactt gcagcgataa agtcgatatc gttgtctaaa ccaaaacgaa
     3241 tatcgtcagc atcttttgga gtaatacctg gcaaactaat agaaacgcct ggtgcattta
     3301 cccctttacg tgatcctagc atacctgcat ttttaacttc tacgactaat tcacggtttg
     3361 cttcgtcttt ttcaatgatt tgcatatcga tcaaaccatc atcaaataaa atgtgtccgc
     3421 caacgtgaac atcgtcaaat aatcctgggt aagtaaccgc gattttttct tttgaaccta
     3481 catgttcagg atccatagag atgcgtgttt gatctcctac ttcaaatttg atgtatcctg
     3541 cacgaccaaa atcagcttct gttgtgcctt gaacagttgt acggatttca gctccttttg
     3601 tatctaaaag aataccgaca tcttttcctg tctttttaac tgcttcacgg accatagtca
     3661 tacgtgataa ttgttcttca tggtcaccat gagaaaaatt aaagcggaag acatttgccc
     3721 cagattcaat caattgagaa ataatttcta ctgagttact tgctggtcct aatgtactaa
     3781 cgattttggt ttttttcatt taaaaaactc tcccattcaa ttttgtttat ttaaagctgt
     3841 acacagctta aatagcttgg tttctttcac tcttaaaatg aaagtgaatt atttagatca
     3901 tatagtgata agtctggttt atgtttgttg ttttcaagtg tatcaatgat gtcagacgca
     3961 acgatttcgt tgtcatggat accgacacat aatccacctt ttccttcttg aagcaattcg
     4021 acagcgtaag caccgaattt acttgccaac acgcggtcgc gtgcgcttgg tgctccacca
     4081 cggacaacgt gtcccaagat agatacacgt gtatgatagt caccaaattc tgaaagtttc
     4141 tcagcgaatt catttccgcc cattacacct tcagccaaga tgatcaagca atgtttcttc
     4201 ccgcgatcgc ggccttcttg gattttttta gcaactgaag ccatatcaaa atcatgttct
     4261 gggatgatga tttcatccgc tccgccagcc acacctgacc ataaagcgat gtctcctgca
     4321 ttgcgtccca ttacttcgat aacgaatgta cgaacatgag aagtcgctgt gtcacgaata
     4381 cggtcaattg attctagtac tgtattgatt gctgtatcaa aaccgattgt gaaatcagtc
     4441 ccaggaatat cattatcgat tgttccagga atacctactg ctgggaaacc gcgttttgtc
     4501 aaagccattg cgccatgata agagccgtct cctccgataa ccactagacc ttcgattccg
     4561 aattttttca attgttcgat tccttttaat tgaccttctt cagttgcaaa ttctggataa
     4621 cgtgcagaat acaagaatgt accaccacgt tggatcttgt cacctacatc tgccacatca
     4681 agacgacgaa tatctccagc aactaaaccg gcaaaaccat aattgatccc gtatacttcc
     4741 agtccttcgt aaataccttt acgaacaacg gcacgaacag ctgcattcat tccaggtgcg
     4801 tctccgccac tggtcaaaat tccgatgcgt ttcataataa acattcacct cattaaaata
     4861 ctttatccta agtatgactt aggtttacaa ccatttttgc gttaaccacg actaacattc
     4921 taacattatt tttctcactt gtcttgattt acggataaaa aaatgaaaaa aaatgaaagc
     4981 aagtagtatt ttttaccgta agttatttga aaaccacatt atcttcgcca agcagataaa
     5041 taagttgccc ctttatactc ttactcttgc tgtcatccac ccaataagca tctgacagaa
     5101 ctacttttcg ttgcgttttt tcgtgataca taactactgg tatatatcct gggtgtttct
     5161 gaaaaatcac ttgtaattgt ttcattatct cgggatcttc ccgttcttct gtaatacgca
     5221 aatagcaagt ttgtgaagga tactgggctt ctaactggtt aggatcagca aagctttctc
     5281 caattagttg cagttcctga ttatatttgc tgatttcgct ccgcccttga acaaagatca
     5341 ctcgatcaac ggcaaacaaa ttacgatatt tacgataaag agttggaaaa actgtgacag
     5401 aaatttctcc actactgtcg gttccttcaa caaaggccat cagttctcct ttttttgtcc
     5461 gaatttctct aacttccttg atcatcacta ataaattgac tggttgatta gggacgatat
     5521 ctgtaatcag ctgaacttgt ttagctaaac gaagacgatc aaacccttct gcaggatgac
     5581 ctgacaaata aatacctaag tactcctctt ccagcttcaa gcgttcttct agtgtatagt
     5641 cagcgacttc ttcttctttt aatgccatga ttcccagcaa gtcaagactt ccaccactgt
     5701 aaacgatatt ttggattttt ccttcgagat caagcatcaa ttgtttcctg ttaggagata
     5761 attcatcaaa aactcctact gctgtcagtg attgcagtaa ctctaatttc agccaacgct
     5821 tatcgatccg tatgaggaat tgatccactg actggaacgg gccattttgt tttctttcgt
     5881 ttaatatatc ttctacaaaa tcacgccgaa taccttttat cgctgtcagt ccgaatctga
     5941 tttcttcctt attgaccaac tcaaaactgg aattactttg attaatggac ggcgaggaaa
     6001 gtttgagttt atttttacgt gcttctgcaa tatattcttt caattttgat gtgttatgcc
     6061 gaacagaatt catcaggctg gtaaagaaag cacctggatg atgggctttt agatacgcca
     6121 tttggaatcc cacgaatgaa taagcaaatg catgtgaccg attgaatcca tagtttgcaa
     6181 atttttcgat atattcatat acggtcgctg ctgttttttc cgaatatccc tgttgtaatg
     6241 ctcctgatac aaaatgcgac ttttcttcat ctaatacgtc ttttttcttt ttactcactg
     6301 cccgtcgcag aatatctgac tgccctaatg taaatccagc catagtcgag gcgatctgca
     6361 tgatttgttc ctgatagacg atcactccat atgtgttttt caaaatcggg atcagtgaat
     6421 catctgggta gcgaatggct tcttttcctt tcttcctggc aatgaaggta tctatatttt
     6481 gcatagggcc tggtcgatac aatgcattga ctgcggcaat atcttcgatg ttttctggat
     6541 ctaatcttcg taaaacgttc cggataccag cagattcaaa ttgaaatact cctgaggttt
     6601 cgcctcgttg aaacaagagc agcgtttttg catcatttag cgggatctct tttaatcgga
     6661 tctcataccc ttctactcgc ttaacagctt tcaaagtaaa atcaataatc gataagttgc
     6721 gtagtcctaa aaagtccatt ttcaaaagac cgattgcttc tacctcattc atcgtatact
     6781 gggtcagaaa agcttcatca gaaccgcgtt ggagcggaac tagttcaagt agattcttat
     6841 cgctgataac tacacctgct gcgtgagtcg aaacatgtct tggcaatcct tctaaaatca
     6901 ctgcagtttt gaataaaagt tggttttttt cgcttgcctg aactaattct actaattgat
     6961 gcgaagtttt ataagcttgg gtcaatgtga ttttcaattg attgggtatt gcttttgacc
     7021 agcggtttgc ttcactttgc gataaaccaa acactctagc tgcatctcta agaaccattt
     7081 ttgctgccat tgtgccaaat gttgcgattt gtgccatatg atattgtcca tacttttctc
     7141 gaacataatt caatacttct tcacgtcgat tgtcaggaat atccaaatcg atatctggca
     7201 tcgtaaagcg ttcggggttt aaaaagcgtt cgaacagcaa atcatattct aatggatcca
     7261 catctgtgat ttctaacaca taggctacta atgaacccgc agcagaacca cgacctgcac
     7321 cggtaacgat tttgtttcta tgagcaaaag ccattacatc ccatacgatc aagaaataat
     7381 catcgaatcc catttgatgg atgacagata actcgtagtc caaacgttct tggtattcct
     7441 ttgtatagtc agtgattcgg cgttccactt gcgaatagca taactctctt aaatattctc
     7501 cagcttgttt tccattagga actggataat gcggaagtaa tttctgatgg aactggaatt
     7561 caaatgaaat cgattcagct aaacgctggg cgcctattac agcttgggaa agacccgctt
     7621 tttcgaatcg tttgatcatt tcttgttctg aaagaagata gacatttgct gttagtggta
     7681 aagatgcaga taaattttct aaaggtattt ggcttccctc tttgatatgt ttcatcactt
     7741 caagtgcaaa aagttcttct tgttgtaaac tagcgatggg atgtaatgca caaagcgaat
     7801 aattttcttt tatcacatac tgataccatt caggcaattg atcaggcgtg ttttctgtca
     7861 agccgatata aaaatttcta gtaaaaacat tttcaagtaa aaactgccaa tgaccgaaaa
     7921 agttatcctc tttattgaaa gcctcagaaa cagaatgatt tgccggaaca acaaacgcta
     7981 gatggtcggt ttctgtcatt tctgcaagtt ccaatttttc ttggatcatt tttcggctgg
     8041 aaagtttcat cagctgctga taacctattt catcttttgc gtacgcaagc aagccataat
     8101 ttttttcttc ataagtataa ctaagatgta atccaatgat tggctgtact ccttcttcta
     8161 cacaaatacg atagaattca ggtgcaccgt ataagacatc tttatccgtt atggctaatg
     8221 aagtgtagcc ttgttttttt gcttcttgta catattctcg aatacgtatc gtactttgta
     8281 aaagagaata agaagtaatt gtataaagtt gtgggaaaaa catcttgcat tccgcctttt
     8341 ttttcgttaa aattcactag cgttaaaagg tttgatcctt ttactttcat taagatagca
     8401 ggcgctgaag ttgattattc cacttcattt gcttgcttgt aatctgtagg aatgagttct
     8461 ttcgcaagaa ctcaaatttt attgagattt ggtctcgttt ctttacattc aaagaaaatc
     8521 tggtaaaatt aagatagaaa agaggtgttc tttatgcgat atatcgttac attattctgg
     8581 gctgtcgttc taggtcaagt agtcggttat attggtgctg cattaacaag cggaacatat
     8641 gattttactt tgacaacaat catttcattc attgcgggtg tcattatcct tttgattggt
     8701 gcagttgcgc caagaaaaga aacctctgcc cattcgtaaa aaaacagcca agagcttgag
     8761 atttctcaag ctctttttta ttttctactc ctcaccacca ttataatctg ctgcgaagaa
     8821 ctttacgaaa gttgaataaa gaaagaagaa tatttgacag aacaaacaaa cttgtcacaa
     8881 taaaaacagc actgtaatta taagcatgcg cgactgtcga tcctagcatg ggacctaaaa
     8941 cttgtccaaa gttgctaaac atctgattgt agctatagat tcggctgact ccttcttgag
     9001 gcgtaatctt actgatcagt gtattgacag aaggcatcaa agcgccagtt gaaaagccta
     9061 aaataaagcg aagtatacct aattggagcg gtgtagtgac gaatgccata ggtaaataac
     9121 agcaaaatga taaaatgagt cctccaatta gaactttttg attcccaatc ttatccccta
     9181 gttttcctag tttcggtgaa gaaaagacag cggaaacacc agctatcgaa acaatcaagc
     9241 cgctgacaaa aaggatattt tctgtacttc cgctcaattc acgaatatat aaggtcaaaa
     9301 tagggctgat cgtagtgatt cctatctgta aaatcaaggt cgtaatgaag agaccgatca
     9361 aaatagagag atgatccatt tttgaaaaaa tttctttggt gcttatcaga tcttttttct
     9421 cgattggatg gaaatcttct ttgactaaga aaatggtcaa taccgttgtg atcatcaaca
     9481 aagcccctgt gatcaagaat acattttcca taccaaacca ctgagccagt gcaccgccca
     9541 ttgaaggtcc gatcagattt ccagcaatcg ctccggtaga caatgttcct aacgcccatc
     9601 cgctcttttc tctaggtgcc tgtgaagcaa tcatcgctgt ggcatttgga atatatccag
     9661 acaaaatccc attccaaaac cgcatgatca aaagccaata cgcgtttggt acaaaagcca
     9721 aagatcccat tgttaatgtc atccctgctg ctgcacggat catcatgagt tttcggcctt
     9781 ttcgatcagc tagatttccc cagattggtg caaccacggc agatgcaaaa gcagtcacag
     9841 agattgctag tcccgaaaac aattcgattt gatcttttgg tgttcctagt tgctcaacat
     9901 aaactggtat gaatggcata actaaactaa tacttgcacc agtgaaaaaa cagccaatcc
     9961 acgcaatcac taaatttttt ctccaattaa tctccatcta tcatccctct ttcgtctctt
    10021 ttatcatacc tattttcgaa taaacaagca acgatctcgc cagtaaaaag agaaaaatcc
    10081 cgcaaaggtc attttatatg taacgttctt tttatgtaaa acaaaaagag atcagaacaa
    10141 atactgttcc aatcccttct ctttagttaa attgttgcta gaatgatgaa gttgataatg
    10201 aataaaatat caacgatcca caaagcaaca gaaacttgat tgtattttcc tttgattact
    10261 ttcacaattg tatagaaaat aaatcctgct gcaatcccat aggaaatgct atagcacaat
    10321 cccataaaga tcgatgcaaa gaaggccggt aaagcttctt ccatatctag ccatttgatg
    10381 tctgcaaaag aagccatcat cattactcca actaaaatca atgctggcgc agttgcttga
    10441 tttggtacaa tggcgatcag tggagagaat aaactactta atgcgaatag cactgccact
    10501 actactgaag tcaaaccagt acgtccaccg gccccgatcc cagctgcaga ttcgacataa
    10561 gttgttgtat tcgatgtacc aaagatagcc cccacagaag tagcgatcgc atcggcaaat
    10621 agtgctttat ccatttttgt tttgaaccca cgaccatctt ccaacgcgat ctcgtcttct
    10681 tttgagaaaa tacctgtgcg gcgtcctgta ccgataaatg ttccgatcgt atcgaaagta
    10741 tcagataaac tgaatgcgat gatcgtcatc aatacttgag gaatcttgga agaatcactg
    10801 aataaagatt gcatgccttc agaaccaaat gctgcaccga aagttgttcc taattcttta
    10861 aatgaattac ctaacgaatt cgtttgccaa tcaatggaac ttaaatcaac aacacccata
    10921 aaaataccaa ggactgtggt cgctacgata ccgataagaa tagccccacg gacatttttt
    10981 acaactaaaa tggctgtcag taccaaacca atcacagcca ataagatagg agcgttgtca
    11041 aagttggcta acgcagggac gattccacca tttatcgtaa catttgtcgc ttttccgcct
    11101 tcaacgacag agctcgaaat agctgactgg tctgctgaaa aagataagaa tcctgcattt
    11161 ttgattccga catacgcaac gaaaataccg atcccgccac caatcgcatg ttgaagactt
    11221 tcgggaatcg cccgaataat catttttcga atatttgtga cagtaataaa aatattgatt
    11281 aatccgcaaa taaacaccat tgccaaggct tgttgccaag aataaccaag cccaaaaacg
    11341 accgtaaaag tgaaaaatgc gttcaatccc ataccaggtg cctgagcata tggtacattt
    11401 gcgaacaatc ccattaccag cgtaccaata atcgatgcaa tgattgtcgc tagaaatact
    11461 gcttggaagg gcatacctga tgctgacaaa atcgtcggat ttacgaataa gatataactc
    11521 atggcaaaga atgtcgttac tcccgccatt atttcagttg atacatttgt attgtttttc
    11581 tttaaaccga aaaacttttc cataaaaagt tccactccct gaattttttt ctgatggaaa
    11641 actataataa taaaaaataa gtaaaatagg gcaaatccat cgaacaattt caaattatat
    11701 agacgtttca ttcgcttttc aacgtttttt taacaaaaaa agcgaaaata atacttaacg
    11761 ttcgtgttta gcttatgttt agctatttat atagccataa ctgtagtttt tgttaggaat
    11821 agctgattgc tcttgttaat tacctaaaat atgctagact aaaacaaatg ctagttgagg
    11881 aaggaaggac ccttattgaa taaaaaatta attgccatcg atctggacgg aactaccctc
    11941 aatcaagatt cgatgattac atctaaaaca aaagagactc taaaaaaagc aatcaatgcc
    12001 ggtcatcatg tcagtattgc tacaggacgc ccattccgaa tgagccatca gttttaccaa
    12061 caattagaat taacaacacc gatggttaat tttaacggcg cattagtaca catccctaat
    12121 cagcactggg atggtgaaag agaaacgttg atcaatcgtg aaatcgcttt tgaaatctta
    12181 tcgcaaaaaa agcagctaaa tttagatttt atcgctgctg aaaatcgtga tacttttttt
    12241 attgacagtt ttgatttctt tgatgaaaaa atttttgctt cttctcgtcc aggagagaag
    12301 aatttgcttt ctcctaaaaa tttgacgaca aatcctacat ctttgcttgt ccgaacagac
    12361 aaacgttttg caggagctgt atctgctgaa ttaacacgtc aatttggcag ttatgtcgat
    12421 gttcggacat ggggtggacc tactgccatc ttagagattg tttcaaaagg aatccaaaaa
    12481 gcaaaaggcg tgcaagagat tgctaactac ctgtctatcg atcaaaaaga cgtcattgcc
    12541 tttggtgacg agcataatga tttggaattg ttggattatg caggttgggg agtagctatg
    12601 gctaacggta ctgaccaact caaaggcatt gcaaatgatg tcactccttt gagcaatcag
    12661 gaagacggtt tagctgttta tctggaaaaa ctacttaaac tataatagag aattagattc
    12721 cacaaaaaag aggttgtgac aattttt
//
LOCUS       DADLIO010000073        12742 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.076, whole genome shotgun sequence.
ACCESSION   DADLIO010000073 DADLIO010000000
VERSION     DADLIO010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12742
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.076"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            101..544
                     /locus_tag="JOX41_002288"
     CDS             101..544
                     /locus_tag="JOX41_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAY6449999.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(550..1734)
                     /locus_tag="JOX41_002289"
     CDS             complement(550..1734)
                     /locus_tag="JOX41_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HAY6450000.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            2002..2700
                     /locus_tag="JOX41_002290"
     CDS             2002..2700
                     /locus_tag="JOX41_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HAY6450001.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2707..3384
                     /gene="nth"
                     /locus_tag="JOX41_002291"
     CDS             2707..3384
                     /gene="nth"
                     /locus_tag="JOX41_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HAY6450002.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(3510..4043)
                     /locus_tag="JOX41_002292"
     CDS             complement(3510..4043)
                     /locus_tag="JOX41_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450003.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(4340..6721)
                     /locus_tag="JOX41_002293"
     CDS             complement(4340..6721)
                     /locus_tag="JOX41_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HAY6450004.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(6711..7358)
                     /gene="recU"
                     /locus_tag="JOX41_002294"
     CDS             complement(6711..7358)
                     /gene="recU"
                     /locus_tag="JOX41_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HAY6450005.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            7422..7961
                     /locus_tag="JOX41_002295"
     CDS             7422..7961
                     /locus_tag="JOX41_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HAY6450006.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            8051..8470
                     /gene="gpsB"
                     /locus_tag="JOX41_002296"
     CDS             8051..8470
                     /gene="gpsB"
                     /locus_tag="JOX41_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HAY6450007.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            8492..8859
                     /gene="rnpB"
                     /locus_tag="JOX41_002297"
     ncRNA           8492..8859
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="JOX41_002297"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9068..10234
                     /locus_tag="JOX41_002298"
     CDS             9068..10234
                     /locus_tag="JOX41_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HAY6450008.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            10280..11776
                     /locus_tag="JOX41_002299"
     CDS             10280..11776
                     /locus_tag="JOX41_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HAY6450009.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            11857..12540
                     /locus_tag="JOX41_002300"
     CDS             11857..12540
                     /locus_tag="JOX41_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAY6450010.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
BASE COUNT         4273 a         2230 c         2630 g         3609 t
ORIGIN      
        1 tttttcttgg tttcagattg ggttttccta caaaatattt ttatctttgt tgaataggaa
       61 acaaaaaaac aatataatga aagaaaaaga aggtgtagaa atggataaaa gacaactgct
      121 aatagaagaa tatctggatt tagctaatga gattattcat cgtaataaac cagaaatgga
      181 aaaagaattt gcaggattta ctctaaatga actagaagtg attgaacata tcgggaaaat
      241 ccctgatcct aacgtgacaa aattagcgaa tgctagttac atgactagag gagccatcag
      301 taagctaaca aaaaaactga tagctagagg gatcataaac acttatcaaa gcgaagagaa
      361 taaaaaagaa atctattttc aattgacgcc aatcggacaa aaaataagga atagacacga
      421 gcaactccat caaaaatggg tacagcgaga tgctactgta tttgaaaata tgtcaaaaga
      481 agaatttgac acagtatttc gttttatcgg tcgatacaga gaatttatac gaagtagcaa
      541 atgaagctac tattttttat tgtagtgata ataggcaaaa atcataagca aaaatccgaa
      601 taccgtcgga agaaatggtg ctgcagcata aagctgtcct gcgattagcg ggccgatgac
      661 gcgcgataga gattgtatac tttgggtacc gcccattaca agaccttgct ggttatctga
      721 gacagaattg gatagttggc cattgaatac aggagtaaaa atagaatcac cgaaaccata
      781 acagataatc ccaaataaaa acaaaatcgg cagtagaaga attccagata atgtgatgaa
      841 tagataggcg aggatttcac tgaacatccc tattcttgtg atctgctgtt ctgaaaattt
      901 tttgagcaat cgaggcataa tgaacaattg cgagacagta tccaagattc caatcaaaga
      961 gaagcttaaa ccaaccaacc cagccttcca ctgaaaggcg tcaatcgaaa attgagaaaa
     1021 gatagattga agagagccag ctgccaacca aacagcaaaa cctgctgtca ataaaggaat
     1081 aacggatgaa atcttgaata attgttgtaa ttggtgaaaa ggtcttacat gggagaaact
     1141 taaatctact gaacgttttt ttattggaag gctttctagc ataaatgtgt agccataaac
     1201 ggcatttaag aaagtaaaga gtgctccaat aaatatagga acagaattcc ccaactcagc
     1261 taatagaccc cctataatag gacccagcgt tgttcctata ccgactaaag cacccatcca
     1321 tccaaaaact ttggttcttt cattaggttc cgtgatgtcg gcaaagtaag catataaggt
     1381 ggagatttct cctgccgtca atccttcaat gatacgacca aggaacaaca tccatatcga
     1441 atttcctaaa ccaaaaagca aatatccgat acttgatcct aataaactga taataaggat
     1501 cggatgacgc ccaaaatgat cacttaagct accgagaatg ggggcagata agaaggcagc
     1561 tagagcataa acagacatga gcaaagtgat atagaaagct tgctgatgta tggagtgaga
     1621 ataaggcagc gttaaaaacg gaagtacagg actgacgata gtaaatccta atccagtgaa
     1681 taagacagag acgtatccaa aaactttaga atgtttattt gtgaaactgt acatgtaaaa
     1741 actcctttat gcaataatgt taacttggaa acaaaaatag tgtatagtaa ttttgtttcc
     1801 ttgtcaacat tctaaggaac agcgaaatct acttaattta tttattccga aaagtgaaga
     1861 tacgcatcaa aaacatgaac aaacaaaaat caagtagacg acattgtaaa tctgaccgat
     1921 cagtgaagta aatagaaaag aaacctgttc ttgcttccca tgtttttttt acgtatactg
     1981 tgattgagcg gaggagaaat catgttgaat ttagaaaatt acttaagcgc tggacaaaca
     2041 gtcatatcta atcttttact taaaaattat cataggatcg gtctacaatc tgaagaattt
     2101 ttatttgttc tacagttgca tatggcacag cttgaaggag atactttccc tgatttgcag
     2161 atgattgcta tggatatggg aatcaaacaa gatcagattt ttcaaatact ggatcgtctc
     2221 gtaacaaatg gatttatcaa gatagaaacg acgattgtca acggtaaaaa agcagatcga
     2281 tataatcttt accccatcta tgatctatta ggtgagtatt taaaaacaca agaaaaaaaa
     2341 tacgaagaaa aaacacaaga aaaagaaatc cagtcagtgt atcaattatt tgaacaagaa
     2401 tttggacgcc cgctttcttc gatcgagttc cagcggatcg gacaatggct agaagaagac
     2461 cattatcagc cggaaatttt gaagctagca ctgcgggaag ccgtattaaa tcaggcttat
     2521 agttttaatt acgttgaccg cattttgcta tcgtgggaaa gaaaaaatct acgtacaaaa
     2581 caacaagtgg aagaagacca aaaacgaaga aaacagcagc ttcttcaaag agaagtagaa
     2641 cagtcagctc aacaagaaga attgccgaaa gtctcactga aaaattggtt ggaggagtag
     2701 cggaatatgt taagcaaaca aaaaacaatg gaagctctag aaacgatgta tggaatgttt
     2761 cccgaagcac atggagaact caagcacaat aatccatttg agttattgat tgcagtgatc
     2821 ttaagtgccc aggcgacaga tgtatcagtg aataaagcaa cgccagattt gtttgcctct
     2881 tttccgacac ccgatgcgtt agcagaagct tcaatcgatg aaatcattct taaaataaaa
     2941 acgattggtt tgtatcgaaa taaagcaaaa aacatcaaag cgtgtgcaca gcagctgatt
     3001 gaacgtttcg atgggcaagt gccaacgtca agagaagaat tgatgtctct tcctggtgta
     3061 ggcagaaaga cagcaaatgt cgtattgggg gatgcattcg ggataccagc aatcgcagta
     3121 gatacccacg tggaacgtgt ctcaaaacgc ctgaggatct gcaaactaga tgctacggtc
     3181 atggaagtag aagaaacact gatgcggaaa gtaccacaag aattatgggt aaagacacat
     3241 catacactga ttttttttgg tagatatcat tgcacggcaa gaaatcccaa gtgcgaggta
     3301 tgtcctttgc tatcaatatg tcaagatggg aaaaatcgga tgcgtctaaa agaaaaggcg
     3361 ctaaaaaaga aaccacgcct gtagacgtgg tttctttaat tgcaaataaa tgtatgaatt
     3421 atcttgttat tatggagaaa agctgtttcg tttatctttt ttgcatgaaa aagtaaatgt
     3481 acatactcag tagctaggat ggtaacttat tacaatttat tgcgataaaa ataaaagttg
     3541 ttatttttat tgggaaaata cccgatgtag aaaataatgc cttccaatat acctataaaa
     3601 taagtccagt attccaaagg attatataaa taagtgacgt atctatctaa aggtgtaata
     3661 aaaatgataa gtgataataa aaaaatacca tttataacta aacataaact aatggatttg
     3721 ggcggtttca ggctcatcag aaaaatatag attctggtga acaacaacca taaaaaagtg
     3781 agaatcattg catgagagct tctttccata aattttcctt taagagtagt gcttaaaagt
     3841 acagaaaaaa taataaatgc aaggatagga gcaattaaag taaatttatt taataataaa
     3901 caaaattttt cagctttttt attcttggaa taacgaggta ttgttttcga taaaaaaaga
     3961 tggtgcagac aaattatgat aattaagcat actatcagat aactcaaaat gaagccttct
     4021 ttcaaaaaat tattcaaaac catatattgt attttttatt tgataataac aatgggatta
     4081 ttaagaagtg gcactaaata aaagactagt gtgtatttag ccgatttaat tataaacaag
     4141 taaatggata aagtatatgt aatgataaaa gaaaaatgga ttttctaatt tttaagctaa
     4201 atgttagatc acacatgtat atgctggata gtcttataaa aaatcatgta atacagcttg
     4261 gtacatgatt tttatttgta gctgtttttt acatagacac aaaaaagaaa ccacgcttgt
     4321 agacgtggtt tcttttttac tatctgtttc cagaagctga ggtgctgctg gatggtgtat
     4381 ggtcatttgc agcatccgct ccgctagttg ctggctcact ggaagaagca ggaggagcag
     4441 atgaagacgg tgtcgagctt tcttcggatg aagaagaagg aaccgttgtt gaagacgctg
     4501 gctcgcttgt ttctgctgtc gtgctttctt ttgaggactc agcagttgat tcgctttgac
     4561 tagtagagct agagctttga gtcgttgtct ctgttgttga gcttccagga gtctggacat
     4621 agctggaaga tggaatagtt gttgatggtg taattgcatt cgatctagct gtatattgat
     4681 ctttgtagta cagttcaccg cccacacgaa ttaatccgct tggcatctcc cagtctgtat
     4741 ttgtcacgtt agctgaaaca tactgcataa gctcgcgata aacatcagag gctacgtgtg
     4801 acgattctga agtgacaggc gtcatttttt tattgtaacc tgtccacacg gaaatcgaat
     4861 aatttggcgt atagcccgca aataggatat ctggatacac cccagaagaa ataccaagtt
     4921 ttgcatactc gtcatctgtg taattggatg ttccggtctt accggcttga tataacccag
     4981 cgatttgcgc attcgtacca gttccttcag tgatcgtatc ttttaaaatg tctgtgatca
     5041 tataagctgt ttctggagac atggctgttt ttccatctgg ctcataagtt tcttctgttc
     5101 cgtcttggaa gacgatttta ttaacatatt gaggtttgta ataagtccct ccattggcga
     5161 aagccgcata ggctgctgcc atttttaagg aagaagctcc gtattttgtc ccatcttgtt
     5221 cttccgtatt actagagatc gcattcgatt gatggatcgt actgtattcg atcccaagat
     5281 tttttaagaa agaagccact ttatctgaac cgacttcatt gaataatttg actgctggaa
     5341 cattacggga taagtaaagt gcttggcgta aagtaatggt gcccatatat tgattatccc
     5401 agtttcctac aggagtcgaa gtcccttcat agttatacgg tgcgtcagta atagtttttc
     5461 cagtagaata tttcaaatat tcaaaagctg gtccgtaatc tgtgacaggt ttcatcgtag
     5521 aaccaaaatc acgggaagta ttcactgcta agttgttgcc taaagttacg tcttctgcga
     5581 tgtgacgtcc gccaatctgg gcttttactt tcccggtatt ggtgtcgata agggtggagg
     5641 caacttgcat ctcgtcgtct gggtaagaga catactgatc cgtgttgacg atatcatata
     5701 gtttcttttg ggcgtccaga tccaaattcg tataaatctc taaaccgtct gtgtagacat
     5761 tcttatctgt tttttcttgt acttcattga tgacttcttt gacataatta tcgacgatct
     5821 tagtattgtc atcggattga gttagttctt gcagaccatc cgttaccggt acattaacag
     5881 cttgatcata ttctgtttga gagatttttt cgttttgaag catcgtatac aaaacagtat
     5941 ctcgtctttt cttcgcctga tctggataaa cataaggatc ataggcggaa ggggcttgag
     6001 gcatcccagc aagcaatgct gtttgcggta aagaaagttc tgataatttc ttaccaaagt
     6061 acatctcaga agctgtctcc atcccgtaca agccgtttga catatacact ttatttacgt
     6121 agtaggtcaa gatctcttgt ttcgattttt tttgttccaa tcttacagcc atccacgctt
     6181 cttgggcctt gcgtttcaga gtctgatcct cggcactggt ggagaagaag gaaagtttga
     6241 tcaattgctg tgtcaaagta cttccgcctt gcagtccgcc agaggtaaag ttagagaggg
     6301 cagaaccgat gatccgaata gggtcaaccc cgatgtgttt ataaaaacgg cgatcttcta
     6361 ccgacacgat cgcatcttct aatgttttcg gtaattcatt cgcagaaatt ttttcacgct
     6421 tttctgcgcc taaatcttcg aatagttcgc catcttgtgt atatagtttg gaagatacgg
     6481 tagcgtctaa ttttttatcc gtcaattcgg gcgcatcttt tgcgtaatac cagaaaagtc
     6541 ctacacctgc taaaaagagg atacagaaaa atgagagtat tcctaaaagg atcttgataa
     6601 ataatccttt tttatgtgtt ccagaggact ttccagaacc tttgccagaa ttcttcttca
     6661 cactcttttt aggagtaggc tgtttctgtc gtctagagct tctagtttgt tcatttgcca
     6721 ttcttgcttt ctccttcaat agataatgtt gataaataga agtcaaccgc gtccaaataa
     6781 ggaatccgcg gagaaatacc agttttgatc tctattccta gttcttcgat caaagataaa
     6841 ggtagtgatt tgcgtccttt ttccttttgg gcgtcccagt aagcaatcaa atgaacacta
     6901 ttcaaataaa aacagcgctt caaagacgaa aaccataaca agacaaagca gaccccattt
     6961 tgttcgaggc atgctttcat atgttcgatt tgatgggcat ggaagttttt aaagggaaaa
     7021 gatgttttgt tcttggtttc ttttgcttca aagtccaagt aaaagcctcg atagacgcca
     7081 ttatagtctg tagttgaggc ttgggtaaag taggcttcct tgatcacagc agcacttctc
     7141 ttaggatagt ctactttcac gatttggata ggggtaggct ttttatggat aaccgccaac
     7201 ccgcgggaaa gataatattt attactttca ttgattgctt cttcaaagcg catcccccga
     7261 ttgccgaatt cagtgatctg atttcttttt tcttgaattt tttcgacggg agaggcattc
     7321 ttataataag gttggccatt tggatagcgc aataccatct ttaatcacac tcctaggcca
     7381 cattatagca aaaaagcgga tagaaagaaa aggaatctga gatggataag tcaaaagtaa
     7441 tctatgtgtc tgggtatcga agtttcgaac tcggtgtttt taaagaaaat gatcctaaaa
     7501 tccaagttgt taaaaatgtt ttaaaaaaag aactccatca gttagcagaa gaagggctgg
     7561 aatgggtact tgtcagtggg aatttgggcg tcgaactatg ggctgtgcaa atagtagcgg
     7621 aattgaaaga agaatatccg gaactatctc ttggtatttt gtatcctttt tctgattttg
     7681 gtaataactg gaatgaaggg aaccaagaaa aaaaacaatt agcagaacaa ttagcagatt
     7741 atgtcgaagc tgttagccat caaccctacc aatcacctag tcagctaaag aatcacactc
     7801 gttttatact tgagcataca gtgggctgtc tgctgatcta tgatgaagaa ttccctggaa
     7861 aaacgaagta tttttttgaa gatgcacaga attaccaagc agatcatccc tacgaaattc
     7921 ggctgatcag tatggacgat cttcaaaatt ttagtgaata atcgatattg tgtttgattt
     7981 atcaactttt ttcctataca atgaaaaagg tagaaatgtt attacgtaaa tgaaaactag
     8041 aggtgtaaat atggcgaatt tggtttatag tcctaaagac attttacaac aagaattcaa
     8101 aacaaaaatg cgcggctatg atcccgttga agttgatgaa ttcttagaca atatcatcaa
     8161 agattatgaa acttacagca aagaactcct tgctttacaa gaagaaaacg atcgattgag
     8221 tgcaaaagta gctcaattat ctaaaactca aggagcagct caaacacgcg tgcaacaaac
     8281 agaggcacca aagagcgcag cagtgaccaa ttttgatatc ttaaaacgct tgtcaaatct
     8341 tgaacgtgaa gtatttggta aaaagcttga tcaacaagca agtgcagtca aaccagcaca
     8401 acctaatcca aataactaca caaatgcaga cacaagctta gatgataatg aaaaaacacg
     8461 tcaattttaa tttttgatta atgaatttgc ggttttcggg taatcgcggt ctgacttgat
     8521 caggctgagg aaagtccatg ctcgcacagg ctgtgatgcc tgtagtgttc gtgcttagcg
     8581 aaaccataag ctaaggtact ctttggagta acggcaggaa aacaagctaa ggcttcggct
     8641 atgcttaagt atccttgaaa gtgccacagt gacgaagcgg ctggggaaac ccatccggtg
     8701 gaacgcggta aacccctcga gcgagcaacc caaacaatgg taggggcgct ttttgtctgg
     8761 aagaagaaca ggacaaaaag gcagtataac tgcagataga tggttaccgc tttgtttttt
     8821 ctccctggaa aagcaaagta cagaacatgg cttatagaaa accgcaaaca tcagggaatt
     8881 aggtcgtgac aaaagtaatg cgttataaga aacaagaaaa acatttgaaa gctatttttc
     8941 aatacttcag atgaatcgtt cttattacaa aacaaacttt tgtatcaccg gttattcgga
     9001 atttgagtaa aagtgtgggg taggactgat gtcccacctc ctttttttat aaataaggag
     9061 attgtgtatg gaaaaaaaca ggaagttcaa cctcgtcgca actgcggcaa gcgggctaga
     9121 agcactggtt ggtaaagaat taagagatct tggaatcgaa tgccaagttg agaacggacg
     9181 tgcacgtttt gaaggaacaa tggaaacgat cgctacagct aatttatggt tacgtacagc
     9241 agatcgagta aaaatcgtgg ttggggaatt cgatgcgtat acgtttgatg aattgtttga
     9301 aaacgtaaaa gcattgcctt gggaagattt tcttccacta gatgcagctt ttcctgtagc
     9361 tggaaaatcg atcaagtcga aactatatag cacacctgat tgccaagcga tcacaaaaaa
     9421 agcaatcgtt gaacgtctcc gtacctatta tcaccgtcca gcttctgtac cactgacgga
     9481 aactggcgca cattttcagt tggaagtagc tttgctgaaa gaccatgtga tggtaactct
     9541 ggatacgaca ggaccaagtt tattcaaacg tggttatcgc ttagaaaaag gtggagcacc
     9601 attgaaagaa aacatggcag cagcacttat tatgttgaca aattggcgaa aagaccgtcc
     9661 attttatgat cctgtatgtg gttcaggtac gctttgtatt gaagcagcct taataggcca
     9721 taatatcgca ccaggattca atcgtgagtt tgcttgcgaa tcttgggatt ggttcagtca
     9781 agaaatcatg gaaaatgttc gatcagcagc cgaagaaaaa gcagattatg atattgaatt
     9841 agatattact ggttcagata tcaatggacg gatgattgaa attgccaaag ccaatgcaga
     9901 agaaatcgga ttaggctctt cgattacctt taagcaacaa gcagtcaaag acttcaaaac
     9961 ggataaagaa tacggggtca tcgtggctaa tccgccttac ggagaacgtc taggagaaga
    10021 agaaactgtt cggaaattat ataaagaaat gggcgatgta ttccgtccat taaaaacatg
    10081 gagtaaatat atcttgacta gcgacttagc gtttgaggaa ttttacggac aaaaagcaac
    10141 caaaaaaaga aaattgtaca atggtgcatt gcgtacggat ctattccagt attggggaac
    10201 tcgtccgcct agaaaaaaag agaaagacga ataatcttac taattgattc attcaattgg
    10261 atgtttggag gaatagggaa tgaaagaaaa agagttttta caagaagtaa aagaaatcaa
    10321 tcttctacaa caagctttag gaatcctcga ttgggataca caaacaggta tgcctgaaaa
    10381 agctagtgca taccgaagtg aagtagacag ctatctttac agcatttatt tttcaaaaaa
    10441 aatcggtcca aaaatcaaag aagccattcg ctatttttct gaacatccgg aagaattgtc
    10501 ggaagttgga actgccgttt ttgccaaagt aaaagaagag tatgatttgg aacatcgcgt
    10561 accggaagat cttatgagaa aatatacagc tgccgtttct tcagcacacg gacaatggca
    10621 aaaagctaga gaaacacaac aattttctga ttttcaacac gcattgaatc aaaatattga
    10681 attaacaaaa cagttgatac cttactggag aaaagatgaa aagacgaatt atgatgtttt
    10741 gctgaatcaa tacgaacccg ggatgactgt cgaaatcctt gataaggtat ttgatcagct
    10801 taaagaagga attctttcga tccgccgtac gctccaagaa aaagggactg aacctgaaac
    10861 agacttttta aatcggagaa tgacgaaaaa acaacagaag agatttgtag tgaaagtaat
    10921 cgaacaactt ggttatgatt ttagtcgtgg tcgtttagat gacactgtcc acccatttat
    10981 gactggaatt aatccgaatg atgcacgaat cacgacacga tggaacgaaa cagatttcaa
    11041 aatggctgtt tttggagtga tccacgaggc tggtcatggt atgtatgaac aagacatcga
    11101 tgataaatat gcgtatacac cggtttatga aggtacatca atgggtatcc atgaatcaca
    11161 atcgttgttt aacgagatca ttattggaag tagtcgcagc ttctggaaaa agcaatatcc
    11221 tttctttcaa gaatgtgcag aaggaacatt cgatgatatt ccttttgaca aattttatcg
    11281 ttcattgaac catacaaaat caagtttggt tcgtatcgag gcagacagtt tgacttaccc
    11341 tctccatatc atcattcgtt atgaaatcga aaaaatgatt ttcaatgaag gggtagatgt
    11401 tgctgaacta cctgaaatat ggaatcaaaa atatgaagag tatctgggaa tacgaccaac
    11461 aaatgatgtg gaaggcatcc tacaagacgt tcattggtca ggtgcaagct ttggttattt
    11521 tccctcttat gcattagggt acatgtatgc ggcacaatta cttcattctt tgcagcaaga
    11581 aatagatgtg gaaaatgttc tagcgtcaga cgattattct ccaatcaaaa actggatgtc
    11641 agagcatatc catcaatatg gtgcatctag aaaaccaaat caattaatca tggatgcaac
    11701 acatgaaccg cttaatccgc aatacctgat cgactatatg aaagacctgt attttaatgt
    11761 atatcaggta aaataaaata caatttacaa agatagctga aattcatcta atctatagat
    11821 gttttcagct atttacttaa gaaagaagtg gaacgaatgg ataaattaca agtgatcgct
    11881 gattatagta tggaccaatt agcgcatgat caaacaggac atgggagcga tcataccaaa
    11941 agagttgtca agttagctga aaaaattttg gagacggaac cgcaggcaga ccgctttgtg
    12001 acgcttgcag cagcttacct acatgatacg attgatgata aagtcgttaa aaatgagaac
    12061 gaggcaaagc aacagcttcg tgtattcctt cgctctttgc caatagtaga ggaacagatc
    12121 tcgatgattt tttccattat cgaaaatatg tccttttcta aaaatctctc tgaagcggcc
    12181 gaactatctc tggaaggtaa gatcgttcaa gacgctgatc gtatcgaagc attaggagca
    12241 atcggcattt tgcgtactgc ttatttcggc ggtggacatg ggcacccgat ttttgatcct
    12301 gaactgtatc cgcaaacatt caaggacaaa gaaaattacc gaaaaggcac gacagtgatc
    12361 aatcattttt atgaaaaact gttcttgctg tctgataaaa tgaatactga ttacggatat
    12421 gaagaagcca aacgaagaga aaccttcatg cgtgaattct tagaagaatt ttttctggaa
    12481 tggtctattg acgatgaaaa ttttactcca gacaattgga tcaaaaataa caaaaaatga
    12541 tggaggttgt gacagaagtg gtcagctcca agatatttcg gatcattttc cgtaaaagtt
    12601 acttctggaa cactgtttac caagaggtcg tgagcctgcc gttcagctcc gagtcacaag
    12661 gaacaatttc aaaaaatagc ttctcgtgtt tgatgaatat tgtaacttgt gattcggaat
    12721 tggcaggaga acaccgttta tt
//
LOCUS       DADLIO010000074        12670 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.077, whole genome shotgun sequence.
ACCESSION   DADLIO010000074 DADLIO010000000
VERSION     DADLIO010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12670
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.077"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            6..305
                     /locus_tag="JOX41_002301"
     CDS             6..305
                     /locus_tag="JOX41_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAY6450011.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="JOX41_002302"
     CDS             378..1739
                     /locus_tag="JOX41_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HAY6450012.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="JOX41_002303"
     CDS             1761..2021
                     /locus_tag="JOX41_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450013.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="JOX41_002304"
     CDS             2035..2787
                     /locus_tag="JOX41_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HAY6450014.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="JOX41_002305"
     CDS             complement(2881..3486)
                     /locus_tag="JOX41_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAY6450015.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="JOX41_002306"
     CDS             complement(3539..4513)
                     /locus_tag="JOX41_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HAY6450016.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5670)
                     /locus_tag="JOX41_002307"
     CDS             complement(4891..5670)
                     /locus_tag="JOX41_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAY6450017.1"
                     /translation="MLLRVVGSIIFRYTLEEVNNVPKYEEIANILRERIRSKEYPLDS
                     FLPNQVDLVKEFGASRMTIKKAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEY
                     EGLSLQMKRRHRSLKSQIIHFDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVL
                     EHTFMPVHLVPGLKKEHLLASIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAE
                     NDPVLEVQQVVYLKDGQPIEYSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="JOX41_002308"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="JOX41_002308"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAY6450018.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="JOX41_002309"
     CDS             7161..8558
                     /locus_tag="JOX41_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAY6450019.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="JOX41_002310"
     CDS             8639..9079
                     /locus_tag="JOX41_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAY6450020.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="JOX41_002311"
     CDS             9227..9553
                     /locus_tag="JOX41_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAY6450021.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="JOX41_002312"
     CDS             9554..10303
                     /locus_tag="JOX41_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450022.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="JOX41_002313"
     CDS             complement(10383..10838)
                     /locus_tag="JOX41_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAY6450023.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="JOX41_002314"
     CDS             complement(11265..11540)
                     /locus_tag="JOX41_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450024.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="JOX41_002315"
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="JOX41_002315"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HAY6450025.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
BASE COUNT         4054 a         2175 c         2588 g         3853 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaag
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaagaact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattcg ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag
//
LOCUS       DADLIO010000075        12635 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.078, whole genome shotgun sequence.
ACCESSION   DADLIO010000075 DADLIO010000000
VERSION     DADLIO010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12635
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.078"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(146..1111)
                     /locus_tag="JOX41_002316"
     CDS             complement(146..1111)
                     /locus_tag="JOX41_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HAY6450026.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            1345..2190
                     /locus_tag="JOX41_002317"
     CDS             1345..2190
                     /locus_tag="JOX41_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAY6450027.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            2381..3568
                     /locus_tag="JOX41_002318"
     CDS             2381..3568
                     /locus_tag="JOX41_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAY6450028.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            3574..3930
                     /locus_tag="JOX41_002319"
     CDS             3574..3930
                     /locus_tag="JOX41_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HAY6450029.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            3932..4270
                     /locus_tag="JOX41_002320"
     CDS             3932..4270
                     /locus_tag="JOX41_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HAY6450030.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            4665..5699
                     /locus_tag="JOX41_002321"
     CDS             4665..5699
                     /locus_tag="JOX41_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAY6450031.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            5692..6378
                     /locus_tag="JOX41_002322"
     CDS             5692..6378
                     /locus_tag="JOX41_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAY6450032.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            6402..7250
                     /locus_tag="JOX41_002323"
     CDS             6402..7250
                     /locus_tag="JOX41_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAY6450033.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            7447..8220
                     /gene="sufC"
                     /locus_tag="JOX41_002324"
     CDS             7447..8220
                     /gene="sufC"
                     /locus_tag="JOX41_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HAY6450034.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            8233..9519
                     /gene="sufD"
                     /locus_tag="JOX41_002325"
     CDS             8233..9519
                     /gene="sufD"
                     /locus_tag="JOX41_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HAY6450035.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            9516..10751
                     /locus_tag="JOX41_002326"
     CDS             9516..10751
                     /locus_tag="JOX41_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAY6450036.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            10738..11208
                     /locus_tag="JOX41_002327"
     CDS             10738..11208
                     /locus_tag="JOX41_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HAY6450037.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            11213..12604
                     /gene="sufB"
                     /locus_tag="JOX41_002328"
     CDS             11213..12604
                     /gene="sufB"
                     /locus_tag="JOX41_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HAY6450038.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
BASE COUNT         4179 a         2366 c         2798 g         3292 t
ORIGIN      
        1 ttacgacctc ttggtaaacg gtgttcaaaa gcttgcatct gcggtaataa gcccaaccag
       61 tacaaaaaca tgaacagctg tttttgtttg gccgttctta ttacttgatg cagaacagct
      121 ttttcacaac ctattgaatc gattattaag cgattttttt agaaacaaat tttccatgtt
      181 tgctatgttc tttaattaag aaacgtacgt aatgagcaag aacgtagaag acaactacac
      241 ttgcaaacag acattccgca acttttaaga aatccaatac gctactatag atacctaaac
      301 tgttgaagta atgaacagta gtaaatatag ctgttgcaga gataacaagc gggaatgtaa
      361 aggctgcata gcttggataa aaacgaagct tgaacaaacg tggaagcata gacagcacaa
      421 cgaaatacaa tacttgagat aaagcgaaca atgctacgac aagataaaaa ttaggttcag
      481 caaagttttt aagataacct gttaggcaaa gagaaccagg tgctgcaacg atcgtaatca
      541 gcggacgtgt cggatgagcc atatttctta cgaaaaagac acgtttgatg atgatcggca
      601 ataagaacgc atagcagatc aatgaaatcc aaaagaaaat ttttccaata agtgggaaga
      661 agttcccggc agttacagtg atgaccccaa atccaacgta aatgataaac cagcttggat
      721 aaattgcttc aattgaaaga tcagctttga taacatggtg ataattgaaa taaaagacaa
      781 ggatcacttg gaagataaca gcgcacagcc aaatgaattt gacaattggt gcaatacttt
      841 catatgaaac aaaataagta caaataacca tgagtgacat cgtaaaagtt ggtgaaacgg
      901 aggcgatgat tggatcatgc aacgtttgtt tcgtgtgttc gaataagata aacaatttaa
      961 caaaaatgaa tatcataaga atcatagaga taccgccagt tagattgcct aaagcaacat
     1021 ggtgatagtc tttaaacaga tttccaaggg aagctaaccc aaggatcaac ccgcagatcg
     1081 ggatcggaat aattttcaaa aagttcttca tatataatat tctccttttt atttaataga
     1141 ttttagtacc aagatgaacg aatacattgt aaaatgaata ggaatgtatg attacgagca
     1201 agcagacagc tgattgtctt catctaagtt actagttgga tcagcaactg ttttgttgta
     1261 catttctatt atagatggtt ttttgtatat ttaaatcaaa tagtttttat agtaattatc
     1321 ataaaaagtt atggaagtgg tgccatgttt aagttattaa cgacttttcg agcagtatat
     1381 gaaacaagaa atttttccag agcagcagaa gtactgtttt tatctcaacc agcagtctcg
     1441 aatcaaatca aacagttgga gcgggaattg aatatcgatc tttttcaacg taacggaaga
     1501 aaagagatgc ttccaactaa gcaagccgac ttattatatg aacggacact ggttttgtta
     1561 gaagaatggg aagaaactca gcaaaaattg ctcaatgaac aaaatgaaga agaagtatgt
     1621 cggatcgttg cttcccacac ctttgctgtc tatcttttgc ctcagttgat gaaacatctg
     1681 atcaaaaggt ttcctaaagt gcattttgag atcgaaatca cgaattctca tgaatcatta
     1741 gaacaagtag cgaaacatga atccgatttt ggttttatcg aaaagccatt agagacttcc
     1801 ggcgtacaaa gatactcttt gatggaagac cagctagtca tcgctgggga cccaaaaagc
     1861 aaattgtggc ttgtaagaga agcaaactct ggtgtttttc attacacgca gcgttatttt
     1921 gaagagatga atatccaaga taagaagatg atcgtgaaaa gtaacgatgt aattgttgcg
     1981 ttgctgaagg aaggaatcgg tcgctcgatt ttgtctaagc gctctgttcc agaaaatgtg
     2041 ccaatgactc cgttgaattt ccatcgatat ttttatttca tccaacgaac caatctggtt
     2101 tctgatcagc tgctagagat tgccgaagag atccttcgat acaatgaaag cacagaaact
     2161 tctcacagcg aggagaatct cagctggtag ataattgcat gtatcaaaaa aagttctatg
     2221 atacactaaa gataagcagt aggcttttgt actgcatttg ctcaagcaac tgcacaaacg
     2281 gaaagttaat ttttcccaaa tgtctatgga aagactttcc attatctaac tggaccgcta
     2341 taataatcag cagtatggtt tttaagaaaa gggatgaaac atggaaaaaa aattaaaagc
     2401 ttcgaacgat aatcgtattg attatggcgt gattttacca gtctttctgt tatgtttgat
     2461 tggtctgctc tcattatatg tagcacttag ccatgatccg aacaatccag cagtcttgaa
     2521 aggcgtaggg atgcaagttg tctggtattt agttggagcg gcagcaatcg ttgtcatcat
     2581 gcatttgaat tccaaatgga tctggaaact gactccttac ctttatggtt tggggttagt
     2641 ggtaatggga ctcttgctca aattctatga tcagaattta gctgcttcaa cagggtctaa
     2701 aaactggttt cgattcggtg cgtttacttt ccagccagca gagttgatga agattgcgta
     2761 catcttgatg atggcactga tcgtaactaa acataatacg caagtaaaag aacggacgat
     2821 gaaatcggac ttttggctga ttgggaagct cttgatcgtg acaataccgg ttttagcatt
     2881 gatcatggcc caagatgact ttggaacgat gcttgtcttt cttgcgatct ttggcgggat
     2941 tttcctgatg tctggaatct cttggcgcat catcgcacct gtagtaatct tggcagtagt
     3001 cgttggagca ggaacgatct tcttggttac gactgaaggc ggaagagact tgctttataa
     3061 agttggattc aaatcttatc agtttgcacg tattgattca tggctggacc ctttccatga
     3121 tacgtcagga atgagttatc agccggccca aggacttttg gcaattggta ccggtggctt
     3181 gtttggtaaa ggattcaacg taagcaatat ctatgtgcct gttcgtgagt ccgatatgat
     3241 ttttaccgtt atcggtgaaa acttcggctt tatcggtggt gcattcgtca ttttcttgta
     3301 ttttatttta atctatcgta tgattcgggt gtgtttcgat acgaataatg aattttacgc
     3361 ctatatcgca agcggtttga tcatgatgct gctgttccat gtctttgaga atattggagc
     3421 aaatatcgga ttacttcctt taacagggat cccattgcct ttcattagtc agggaggatc
     3481 ctcgatttta gggaacatga tcggtatcgg gttgatatta tcgatgagat accaaaatga
     3541 agcacctgca agatcttcaa ggaggtaaga aaattgtaca ccttttactg gtacccgaaa
     3601 tgttcaacat gcaaaaaagc caaagcgtgg ttagaccagc atggcgttag ttatcaaacc
     3661 gttgatatga tcaaagaagt accgaaggcc tcaacgattg agacttggct agaaacgagt
     3721 caagtaccaa tccgtcgcct gttcaacaca agcgggatga aatatcggga acttggactg
     3781 aaagatcaag taggcgagtt tacggcttca aaagcgagcc aagtcttatc gacagatggt
     3841 atgctgatca agcgaccact gatcttacga gaggaccagc ttgttgcaat tggattcaat
     3901 gaaaaaattt atgaaggaga actgatataa aatggcaggc aagcatttga agaaaaagga
     3961 caacctttgg atcttattta atggaaaaga atactgtgtt ggtttgacaa atgaagcgca
     4021 agaagaactt ggagacatca cgtttgccaa tctgccaaaa gcaggacaat cgctaaaaaa
     4081 agatgaacct ctgatcgaag ttgaagcgga aaaagcggtc aatgaatttg ccagcccgct
     4141 aacgggtaca gtttcttctg ttaatgataa aatcggtgaa gatatcaata tcttgaatga
     4201 ttcagatgaa atgaatgcgt ggatcttaag tttcaaagat gttgatccaa aagaatttga
     4261 cgaattataa aatcagaaaa tcacttgaaa aaagttgaca ctgattcttc cagttgctat
     4321 aatcataagc aatcctatat gaaacgagaa agctttgaaa agaagagtac atgtcacgga
     4381 cgtttgaaga gagccctgtt tgctgaaaat gggtaacgaa aatgagatgg aagatggtct
     4441 tagagcagag taagcgagcg taagcaaact tactacggga gtgcccgtta cagcgcgaca
     4501 gtatacggaa agaagctaag tccaagtact ggaagaggct gttattgcga agtaacggta
     4561 aatcaaggtg gtaacacgga agttcaagct ttcgtccttt tgcttaaggc aagagggcga
     4621 aggctttttt gtttgaaaaa ttataagaga aagatgtgaa tggcatgtca ttaatccaac
     4681 taacgaatgt caaaaagaca ttcaatggga aaaacggaaa catccaagcc gtcaatgacg
     4741 tttcactaaa cgttgaaaaa ggggatattt atggaatcgt cggctattct ggcgcaggaa
     4801 aaagtacatt agtccgtctc ctgaatggac ttgagcttcc cacgagcggc gaagtgatcg
     4861 taaacgatca agatattaca aaattaaaaa acaaagaatt acgtacattc cgaaagaaaa
     4921 tcggtatgat cttccagcat ttcaacctgt tatggtcaag aactgtactt gaaaatatcc
     4981 agctgccgct ggaattagct ggcgtaccaa agagcaaacg taaagaacgg gcagaagaac
     5041 tgttgcgttt agtcgggtta gaaggacgcg gacaagcata tccttcacaa ctttccggcg
     5101 gacagaaaca acgcgtcggt atcgcacgag cattggcaaa tgatcctgag atcctgcttt
     5161 gtgatgaggc tactagcgca ttggacccgc aaacaacaga agaagtatta gacttattgt
     5221 tagcgatcaa taagaaattg aatttgacca tcgtcttgat cacacatgaa atgaatgtga
     5281 tccgcaaaat ctgcaacaaa gtcgctgtga tggagttggg gaaagtcgta gaagaaggag
     5341 acgtattgac tgtcttcaga caaccgaaaa aagaagtaac caaacgcttt gtacaacaag
     5401 acatcgaacc agaagctgat tcgacagaac tattagctga actcatcaaa gaaaatccaa
     5461 gcggccgttt ggcaactttg acctttagcg aaagaaatgc caacgagcca gtcatttccc
     5521 aagcgattcg acgctataac atcgatgtca acgttgtgta tggaaagatc aaacaagtga
     5581 aagaaggttc ctttggttca ttgactgtct tgatgactgg tgaaaccaaa gaattagatc
     5641 aagcagaagt gttcatcaaa gaacaaggag taggaattga ggtgatccat cgtggataaa
     5701 agcttttcag aaacatatct agattttaaa caaatcaacc cggaaacgat gaatcaggct
     5761 atccttgata cactatatat gacattaatc tcaatggtct tagtgacgat catcggatta
     5821 gttttgggat tgatccttta ctctattgga cgcaaaaaca aaccgtatgc tcgaatcatt
     5881 tatggaatcg tatcgatcat cagtaatatt ttccggtcaa cgccatttat gatcctgatg
     5941 gttttgatca ttccatttac taaagcaatc gtaggcacta tgctaggtgc gcaagcagcc
     6001 attccagctc ttgttttatc cgcagcacca ttttatgccc gtctagtaga gattgctttt
     6061 cgtgaagtca gccctggtgt actggaagca gcagatgcaa tgggagcaag ttactgggaa
     6121 atcatctgga aggtcttgat acctgaaagt attcccgcat tgatttctgg attaacagtt
     6181 acaacgatct cgatgatcgg atttactgcg atggccggcg cgatcggcgc aggtggactt
     6241 ggaggtcttg cttggcagga aggctaccag cgtggtaatc taacagtgac attcgttgcg
     6301 actttaatta ttttactaat cgtatttatc gttcaaggaa tcggtgattt cttaactaag
     6361 aaaacagaca aaagataata ggatataggg ggatgtagga tatgaaaaag aaaatttttg
     6421 gatttgcagc agcgcttttg ctgactgtag gattagcagc atgcggtaac aacagcgaca
     6481 gcaaagattc agcaaataaa gcagacgaca cgacattgaa agtcggcgct tcaccgacac
     6541 cgcacgcaga gattttggaa catgtgaaac cattattgaa agatgaagga atcgatcttg
     6601 aaatcgtcaa attcgatgac tatgtattac cgaaccaatc tttggaagaa ggcgacattg
     6661 atgccaatta cttccagcat attccttatt tgaacaaaga aatcaaagaa aaaggatatg
     6721 actttgtcaa tgccggtgct gtccacatcg aaccaatggg cttgtactct aaaaaagtca
     6781 aagatgtttc cgaattaaaa gatggtgcaa caatcattac ttcaaattct gaatcagact
     6841 ggggacgcat catcacaatt ctacaagatg ctggcttagt caaagtcaaa gatggagtag
     6901 atctggaaac agcaacattc gatgatattg aagaaaaccc taagaacttg aagttcaacc
     6961 atacgatcga cccatcactt ttagcttcta cgtaccaaaa tgatgaaggt gacctagttg
     7021 caatcaacgc aaacttcgct tacggcgcag ggttgaatcc attagaagat gccgtattgc
     7081 ttgaaaagga caactctcct tacgtgaata ttattgcgac tcgtaaaggt gatgaagaca
     7141 gtgacaaaat caaaaaactg attgaagtgc ttcaccgcaa agaagtccaa gaatggatca
     7201 cagacaaatg gggcggctct gttaaaccag taaaggctga tgcaaaataa ggtatggaac
     7261 aaaaaagatg agaaataagt ctgtaatggc ttatttctca tcttttttat acctattcta
     7321 atttagaaat caaaattgtt taataataaa taaaagatat ttgattttag taaggaaggt
     7381 cattgcgctt cattctcaat tagtctaaaa tgagtgagaa cgaaagagaa tttgggggta
     7441 taatgcatgt ctgtcttaga aataaaaaat ctacatgtgt cgatcgagga aaaagaaatc
     7501 cttaaaggcg taaacctaac aatgaaaacc ggagaaatcc atgccatcat gggacctaac
     7561 ggcacaggaa aatctacctt atctgccgct atcatgggca atccaaacta tgaagtaaca
     7621 gaaggcgaaa ttttgtttga cgggaaaaat gttttagact tggaagtaga tgaacgtgcg
     7681 cgacttggct tatttttagc tatgcaatat ccaagtgaga taccaggtat cacgaatgcg
     7741 gaattcatgc gtgcagcgat caatgcgaaa cgtgatgaaa acgacaaaat ttctgttatg
     7801 gcatttttga aaaagttaga tgaaaaaatg gctttactaa atatgccaga agaaatggct
     7861 gaacgttatc tgaacgaagg tttttctggc ggagaaaaga aacggaatga gatcctgcaa
     7921 ttgttgatgt tagaacctac atttgcaatt ttagacgaaa tcgattcagg tctggatatc
     7981 gatgctttga aagtcgttgc taaaggagta aatgaaatgc gcggagacaa tttcggtgca
     8041 ttgatcatca cccactatca acgattattg aactatatca cacctgatgt cgttcacatc
     8101 atgatggaag gccgagtagt catgacaggg aatgctgacc tagctaaacg tctggaagca
     8161 gaaggctacg ctggtatcag taaagaatta ggaatcgact ataaagaaga agaagcgtaa
     8221 gggggagcaa gaatgaaaga aaaaaactgg ctcgattatc ttgacgcggt aaatgatttt
     8281 tctttaagta aaggcgaacc tgattggatg agaaccttcc gtcaagacgc actagcgaaa
     8341 gcagatgaac tgccattgcc gcatatcgat cgggtgaaat tccatcgctg gtcgttattt
     8401 gatgtgaaag aaacacaaac catcagtgaa acaggcacga ttccggcatt tgatgcaatg
     8461 aaagacaatc ctgtgcttgt ccaacaaggt tcatggacga tttttgaaca actgcctgtg
     8521 gaattagcag aaaaaggagt catttttacc gacttgttca ctgcaatgat cgaatatcca
     8581 gaactagtcc aagaatatta tatgaaaaaa gcagtaaaca tgaacgaaga ccaattgact
     8641 gcactccatg tagcttttat gaacagcggt attttcctgt atgtgcctaa aaatgtcgtg
     8701 atcgatgaac cactcgagtc cttattcatt caagatggcg catccgatga gcacttcttc
     8761 aagcatgtgt tgatcgtggc agatgaacat agtgaatttt cttatctgga acgtttccag
     8821 acaaccaaag aacaagtagc aaaatcatca ggtaatatca tcgtggaagt catcgctaaa
     8881 gctggttcaa aaatcaaata ttcagccgta gatcaattag gagaaaatat tacttcttat
     8941 atgaatcgcc gtgggcacat tttacgagat gcttctgtcg actgggcaat tggtgtcatg
     9001 aatgacggtc atgtgatcgc tgactttgac tcagatttag caggagaagg tgcacacgca
     9061 gaagtcaaaa tcgtggcaat cagctcgggc agacaaatcc aaggaatcga tacacgagta
     9121 accaataaag cccctcatac gatcgggcat attttgcaac acggagtgat ccgagaaaaa
     9181 ggaacattga cctttaatgg tatcggccac atcttgaaag gggcaaaagg tgcagatgcc
     9241 caacaagaaa gtcgtgtctt gatgctttct gataaagcac gtggtgatgc gaatcctatt
     9301 cttttgatcg atgaaaacga agtaactgct ggacatgctg ccagtgtagg acgagttgat
     9361 ccagaagaaa tgtactatct gatgagtaga ggattgcata aagaagaagc agagcgctta
     9421 gtgattcgag gattcctcgg ttctgtctta acagcaatcc ctgtagaaca agttcggaaa
     9481 gaattagtcg aagtaatcga agggaagttg aatggatgat cgatgctaaa aagctacgca
     9541 atgattttcc tatcttattt caagacgtca atgatgaacc tttagtttat ctggataatg
     9601 cagcgacgac ccaaaagcca aaacaagtac tccaggcatt agcgtactat tacgaacacg
     9661 ataacgccaa tgttcatcgc ggtgtccata cgttagcaga acgcgcgacc catgattatg
     9721 aacaagcaag agaaaaagta cgggcgttca tccatgcaaa agaaacagca gaagtgctgt
     9781 ttactcgtgg tacgacgaca agcttgaatt gggtagccag aaccttcggc gaccgctata
     9841 tcaaagcagg agacgagata gtgctctctt acatggaaca tcattctaat gttatcccgt
     9901 ggcagcagtt ggcaaaacga acaggtgctg tcttgaaata tatcgaacta acagaagaag
     9961 gcttcctgga tatggaggat gcagcgaaaa agattacgga caaaaccaaa atcgtctcca
    10021 ttgctcatgt atccaatgtc ttaggtgtct tcaatcctgt tcaagaatta gctgaacttg
    10081 tccatgaaaa cggcggggtc atcgtagtag atggtgctca atctgccccg cacatggcca
    10141 ttgatgtcca agcactagac tgtgatttct ttgctttcag cggacacaaa atgtgcggac
    10201 caacaggtat tggtgtttta tatggtaaac gaaaatggtt agaagaaatg gaacctgttg
    10261 aatttggtgg cgaaatgatc gattttgtcg aattatacga cagtacatgg aaagaactac
    10321 cttggaaatt cgaagcaggg acaccaaata tcgccggcgc tatcgcatta ggccatgcaa
    10381 tcgattattt gcaaaaactc ggtatggaca atatccatcg atatgaagaa gaactagccg
    10441 cttatgtgtt gccaaaatta caagcaattg atggattgac tgtttatggt ccacaagacc
    10501 cgaattttcg gacaggagtc gttgcattca atttggatgg gttacatccc catgatgtcg
    10561 cgacagcttt agacatggaa ggggtagccg tcagagcagg tcatcattgt gcgcaaccgc
    10621 tattgaagta ccttgaagta tcagcgactg ctcgcgcgag cttttatttc tacaacacaa
    10681 cgcaagacgc cgaccgttta gttgaagcaa tcatggcaac aaaggagttt ttccaacatg
    10741 ggactatcta aattagacaa tttataccgt caagtgatct tggatcattc ttcccatccg
    10801 catcatcgtg gaagcttgac tgactcgaca agcaagatcg aattgaacaa ccccacatgt
    10861 ggagatgtga tcgaattgca agtcgatgta aaagacggaa tcatcaaaaa tatcgccttt
    10921 gacggcagtg gctgctccat cagtacggca agtgcctcga tgatgacaga cgccgtcatc
    10981 ggaaaatcaa tagaagaagc agaacattta actgtagact ttctacagct tgtccaagga
    11041 aaagaagtca aagatcccga ccaattaggc gatgctgcta tgcttggtgg tgtagctaaa
    11101 tttcccgctc ggatcaaatg tgcgacactt gcctggaaag cactaggaaa agcaatggaa
    11161 aacgatggta ccgcagcttt ccatcattac cacaaggaag aggagtgaga acatgggcgt
    11221 accagaatta gaagaatata aattcgggtt tcacgatgat gtcgaaccgg ttttcagtac
    11281 aggagaaggc ttgacagaag aagtgatccg tgagatgtca agaatcaaag gcgaaccaga
    11341 atggatgctt gaattccgtc tgaaatctct agaaacattt aacaaaatgc caatgcaaac
    11401 atggggcccc gacctttcag acatcgattt cgatgccatc aaatattacc aaaaaccaag
    11461 tgacaaaccc gctcgtgact gggaagacgt accagaaaaa atcaaagata catttgaaaa
    11521 gattggtata ccagaagctg aacgagctta tctagccggt gcttccgcac aatatgaatc
    11581 agaagtcgtg taccataata tgaaagatga attcgaaaag ttaggaatcg tctttactga
    11641 cactgactct gctttgaaag aataccctga attattcaaa gagtactttt caaaacttgt
    11701 accgccaacc gacaacaaat tagcagcgct gaattcagcc gtatggtcag gtgggacctt
    11761 tatttacgtg ccaaaaggcg tcaaagtcga tgttccatta caaacgtact tccggatcaa
    11821 tgcggaaaac acggggcaat tcgaacgtac gctgatcatt gttgacgaag gagcaagcat
    11881 ccactatgtc gaaggttgta cggcacctac ttattcaagt aacagcctgc atgccgccat
    11941 cgtagaaatc tttacaagaa aagatgcgta ttgccgttac acaacgatcc aaaactggtc
    12001 agacaatgtg tacaacttag taaccaaacg agcaaaagca tacgaaggcg caaccgttga
    12061 atggatcgac ggaaacctag gtgcaaaaac aacgatgaaa tacccaagtg tttacttaga
    12121 tggaaaaggt gcacgaggca ccatgctctc catcgccttt gcaggagcaa accaaatcca
    12181 agatacgggt gcaaaaatga tccacaatgc accaaataca tctagctcta tcgtctctaa
    12241 atcaatttca aaagacggcg gagaagtaaa ctatcgagga caagtaacct ttgccaaaaa
    12301 cagtgcgggt tcgatctctc atatcgaatg tgacacgatc atcatggacg aatggtcgaa
    12361 atccgatacg atcccattca atgagatcca caacagccaa gtctctttag aacacgaagc
    12421 caaagtctca aaaatctcag aagaacaact ctactatctg atgagccgag gcctgaccga
    12481 atctgaagca actgaaatga tcgtcatggg ctttgttgaa ccattcacca aagaacttcc
    12541 aatggaatat gcagtcgaac tcaatcgatt gatcagttat gagatggaag gcagtgttgg
    12601 gtaaacctgt tataggagct agaacccttg atata
//
LOCUS       DADLIO010000076        12601 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.079, whole genome shotgun sequence.
ACCESSION   DADLIO010000076 DADLIO010000000
VERSION     DADLIO010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12601)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12601)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12601
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.079"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(324..893)
                     /locus_tag="JOX41_002329"
     CDS             complement(324..893)
                     /locus_tag="JOX41_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAY6450039.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1214..2257)
                     /locus_tag="JOX41_002330"
                     /pseudo
     CDS             complement(1214..2257)
                     /locus_tag="JOX41_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327800.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2611..3459
                     /locus_tag="JOX41_002331"
     CDS             2611..3459
                     /locus_tag="JOX41_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HAY6450040.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPVPVR"
     gene            3473..4546
                     /locus_tag="JOX41_002332"
     CDS             3473..4546
                     /locus_tag="JOX41_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HAY6450041.1"
                     /translation="MEKIKDYFINFVLFLVYFIIVLFALVFNNSLGWFLLAFFTLYVS
                     WSLISLSSFLKKLSVTCTLQPLVYRKKSMQVIFSIAKKRTFSLPLPRLQIGFPAIFAE
                     KKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFRKSAKREISFPVTVL
                     PAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNRIDWKLSAHTQEWLY
                     REYDYQEEECSPLFCFWGSHSPKFEPLLDLYFSLWHLRKEKQPELLILGNRAFHGKDP
                     GHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIETLSKDRTVYLVYFV
                     EKQLMVQEKDKICSLPGGEWIDD"
     gene            4536..6707
                     /locus_tag="JOX41_002333"
     CDS             4536..6707
                     /locus_tag="JOX41_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HAY6450042.1"
                     /translation="MTIKWEKWLCGVYSFVILSVGAPIFVVANQLQNSYLLILTIGVL
                     CLIVCCIPKKWVRLLLSLPVMIGCLFLYFPSKTFSLLWILQFFSSVTEEFFHLSQGKL
                     YYLPEKTAFFLIMLLIYLFITLTVDYDYLYAPFLSLMAYFMMLTVFREKDLLYEMIAV
                     VTVLFVYLAARQFFSMRLLSGNTRFQSLTTVLLICFLTISAILPLYLPKVHQSLEETS
                     EPIREYLNDEGLYDTLHEYQLTGSARTGFSENDEQLGGPLYDNGEVVFTANQKGNGYW
                     KIENKNHYTGSGWIEDQDAPIQPIQEFPVDITSYQTVMEDKENITLTLKKQAFLPYPY
                     GNTTLTDFSLASGQTLYYLPESQRFIPVPNESTRSATLQTERLVFTREELKSSQLKAD
                     DLENQQTNLQLPKSLPKRIEDLAVELTKNEATLIRKVEAVEQYLKTSGNFRYSKTDTG
                     HTPKEHDYVDYFLFDSKVGYCDNFSTSMVVLLRTLGIPARWTKGFTNGLRTGTDNQGN
                     EEYSILNSHAHSWPEVYFPGFGWLPFEPTPSFANPMGSQPVAETTETVQPAIEQPNES
                     ENMAETISSERSEVIPSEETTLTPAYKIVLFSLGVCLYVLLFFLLLFRKSLRWTSYLI
                     YLHFFASTNTIAYQKLLNHLETLVPRKPAESLQEYSLRIEQEFKLDLRFIRLTTQYEA
                     EIYGRQADPVNFDKKTYLEITHIIRKTVYKKVLTKGSRFKK"
     gene            complement(6819..8975)
                     /gene="copB"
                     /locus_tag="JOX41_002334"
     CDS             complement(6819..8975)
                     /gene="copB"
                     /locus_tag="JOX41_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HAY6450043.1"
                     /translation="MHMGHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHMGHNHG
                     DIANSKQMDHSMHMDHDHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGMEFPFQ
                     VTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYIYSVYS
                     FIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPESVKRL
                     TKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGIKKQAN
                     DKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAKWLFYV
                     ALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAAKNGLL
                     LKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGALEANAN
                     HPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKNQQVKIVNEKEVERLGLNVEQ
                     ALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVMLTGDNK
                     NAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLARASIGM
                     AIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILAIPLAA
                     GILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
     gene            complement(9118..11304)
                     /locus_tag="JOX41_002335"
     CDS             complement(9118..11304)
                     /locus_tag="JOX41_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HAY6450044.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKSKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGLIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMSSSLASIAQTIELSRVTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            complement(11304..11513)
                     /gene="copZ"
                     /locus_tag="JOX41_002336"
     CDS             complement(11304..11513)
                     /gene="copZ"
                     /locus_tag="JOX41_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HAY6450045.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(11526..11966)
                     /locus_tag="JOX41_002337"
     CDS             complement(11526..11966)
                     /locus_tag="JOX41_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HAY6450046.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(12040..12513)
                     /locus_tag="JOX41_002338"
     CDS             complement(12040..12513)
                     /locus_tag="JOX41_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation family protein"
                     /protein_id="HAY6450047.1"
                     /translation="MGRENRPSQGRSKKSPAFRIQAKKWFLQEQQSFMVSNPSWIVEG
                     NYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLKRKINKKSRPDMPESFSEKLNRK
                     YLEFLSFIWHFEGNNEPKIQQLIQVANARNKLIILKTRREKQEFLTKLKIESKNN"
BASE COUNT         3537 a         2652 c         2235 g         4177 t
ORIGIN      
        1 gtcaaggaca atcggaatag catacggaaa gaagttctgc accttataaa atttgtcaaa
       61 aaaactgttg ccattccaag tgaaaaaaag atcaatgaat caactagaaa actatataga
      121 agagcaaata aaaaagcact caaattgagt gcttttttaa gctcactatc actaaaacta
      181 tcactaattt tatttataag cgaacatgtt tctatcactg attttttaaa tctagcgaaa
      241 aacccttatc ttaaaggcgt tcgttcaatt ctttggcaag gtcttcaaag cctggcttgc
      301 ctagaagtgc gaacatggtt ttcttatagc tcatgtagaa aaattttctt gatgatgatt
      361 ttatccatca attgagattg actgttttgc tctcctatga tttcagctat gattgtccga
      421 ttttgcggtt ttcttcttaa ctggtagttg attttcccag tttccatcaa ctcgctaagc
      481 atatccacga ctccgccaaa tccggtcttt ttcgtaataa aacctagtgc taccattcgt
      541 tcatctagat tttttgctgt aatcgtcaca ccagtaatga gcgagtgctg taatgtttgg
      601 gccagctctt ccatcccttc agcattggat acgacggaag ctgttttgtt aataggttct
      661 tcgtttattt cttttggttc tttcctctcc actttcactg tttgacgaag gacatctagt
      721 tcttgcaaga gcgtttcgta ttgttcttgg gtcagcatca cgccagctac tttttcacga
      781 ttaaatatat atacgccagt tcccgcgtct cgcgcttgag caaatacatc catcggcgat
      841 cgtttcactt ctgtgatcga agatgtggga acttctaatt tctttaattc caatggattt
      901 cctcctttac taatcgcttt ttattatagc acagactgac ttgttttgat cttttttcca
      961 aaggttttat cggtttttgc ctaaccagta attgatatcg gtaagaagtc tttcgatacc
     1021 aaatgaagga tggtacagat acgttttttt gatcttcgtt atggtctagt ggaaaaaaat
     1081 gatcggtgat cactagatct gcataccgag gcggcttatt tcgagtacat acatgtatag
     1141 agatccgttt tcgatgtctt agcgttttgt tcagtacccc agcaagtctt cttgcttctt
     1201 ggtgttcata gcgaaaaaaa aagacgattt tcacttcagg agggtggaca tctaaatacc
     1261 ctcgttcctg gagtgttttc agtaaaagca tcccccactc tactgcgggg tgtgcaaatg
     1321 cttgttggat cgctagccga aattgatata gtttatcttt ggaattggga aatttttcta
     1381 atgtttcctg ataataacga acttcttcta tcagccggtc atggatacca attacgtaac
     1441 gaagccattc ttggtaaagt acttttgtca gctttgattt gttttcgctc tcaaattcgc
     1501 tattcagcca aaacagcgaa tcaagctttt cagtcacaat cgtcaatttc cgatagtctt
     1561 gtgtctcttc tatccgtttc caccgctttt cagtaatctg gttacagctc aagcgcaaaa
     1621 ttgctagata atttttttct tttattggca aaatctgctc ttctctaaat agcaattcag
     1681 gaaacaattc aaagaatagt gttcgactgt ctcctaaaat ctcgatttct gccggatcct
     1741 ttctttgctt caataattgg atgaacatct cagaaaagga ctgctctcca tcatctgcaa
     1801 aaaaatgcgg aaaatctttc aaaaagcaaa acagcagata tcttactttt ctttctgaac
     1861 caaagatctg tgctttttta taagaaaaag aaaggtggta ctcgccaaac cactttctca
     1921 atcgctcttg cgtagaacga tcgtacttct gctcgtaagg ttcattcaat agcagatttt
     1981 tcagtaaaca aaacgggggt gattggatca gaaaaacaaa caagagataa ggttcgctat
     2041 atccttgatc ataaactaac tgaacggttt tcttatgaag aatcagctgg atgggacagt
     2101 cgctttccgc caaacgtttc agatgccgat ccactgtttt aacatcgatt ttcagttctt
     2161 cagctaaatc agcttttcgc cagatcaaat ctttcattag attgattagt gaaaataaat
     2221 tctgtgcatt ttttgataat agtttttgcc atctcatcga tcatttctca cctgatttct
     2281 aaacatattg tttgatcaaa atgggttcac tcctaaaaag ataaaaaact ccctttctat
     2341 ttatttaaat acgcaaattt tcctcattat ttttaatttt actcaattta atcgtattct
     2401 catttcaaaa cgaatgtact ttaaaaaaac ataataaaat cactttgctt gtaggatgta
     2461 ttcccttcca ttacaatgaa ataaatagca attttatgag aaggtgatgt gaaaatggaa
     2521 gaaaaaatcg aagaatccaa acaaaaaatc gatcagttga tacaagaatt agaaaaagcg
     2581 gtcatcggca aacgttcaac tatccaattg atgatcgtgg ccctattagc aggtggtcat
     2641 gtcttattcg aagatattcc cggtgtaggt aaaacgttac tggtcaaagc actagcaaaa
     2701 gctgtacagg gaaccttcag cagagtccaa tgtactcctg atctgctgcc tagtgatatt
     2761 cttggttttt ccgtatacaa ttcacaatca aaagagtttg aatttcgtcc gggaccgatc
     2821 tttaccacga tcttgttggc agatgagatc aatcgcacga ctcctcgtac tcagtcagca
     2881 cttttagaag caatggccga gaatcatgca acgatcgaca acaatacata ccctctagac
     2941 aatcattttt ttgtcttagc tacgcaaaat ccaatcgagt atgaaggaac atatcctttg
     3001 ccggaagcac agctcgatcg ttttttattc cgactacaaa tcggttatcc ttcttttgat
     3061 gacgaacttt tgctactttt agataaattc gaaaaagtgt tggataactt aaatgaagta
     3121 ttgaacagtt atgaaataga agaaataaaa acaaatgtgg cgaatgtctt tgtcagtccc
     3181 gaagtggcat cttatgcctt gcagttagtg tcagcaacaa gaagccatgc tgccatccag
     3241 cttggcatca gtccacgagg aagcctttcc tttattcagg cagcaaaagc ttatgcttta
     3301 atccatggga gaaattacgt cacgcccaaa gatttgcagg atttagttcc ttacgtgttt
     3361 tcccatcgcc tgatttttta cgatcgttca ttgaaggaag acgaaaaaaa acaaatcatt
     3421 catactcttg ttgcacaaat tcctgttcct gtgaggtaga ttgaggtaga taatggaaaa
     3481 aatcaaagat tatttcatta attttgtgtt atttctggta tatttcatca ttgtgctttt
     3541 tgctcttgta ttcaacaatt ctttaggctg gttcttgttg gcctttttta ctctttatgt
     3601 atcatggagc ttgatttcat taagcagctt tctaaagaaa ctttcggtta cttgtacatt
     3661 gcagccactc gtttatcgca aaaaaagtat gcaggttatt ttttccatag caaaaaagag
     3721 aactttttct ttacctctcc ctcgtttaca aatcggcttc ccagcaatct ttgcagaaaa
     3781 aaaacaagag attttgattc ttacaaataa accgcaagaa gtccaattgc tttggcagcc
     3841 aaaagaaaga ggatgccatg aaacattaac tgtcattttt acagcctatg atagtctagg
     3901 acttttcaga aaaagtgcaa aaagagagat ctcttttcct gtgactgttc tgcctgcttt
     3961 ttgtaagatt caagcagaaa aattacagag agttctggaa aaaaaacagc agctgaacgc
     4021 gtaccaaaga ggtcttgatt ttcgggaaca tcgcgcttat cgtccaggtg attctttcaa
     4081 ccgaatcgat tggaaattgt ctgctcatac tcaagagtgg ttataccgtg aatacgatta
     4141 tcaagaagaa gaatgttctc ctcttttttg cttttggggt tcgcacagtc caaaatttga
     4201 acctctgcta gacttgtatt tttctttatg gcatttgaga aaagaaaagc agccggaact
     4261 tctgatatta ggcaaccgcg cctttcatgg caaagacccc ggtcatacct attttgcttc
     4321 tttggaagct ggcgatgaga aagctttttt cgcacaccta aaaaaatatg caaaaaaaca
     4381 aatcgtcctc tttgttcctg agaattctcc tgaagtctca gaagctattg aaacattgtc
     4441 aaaagatcga acggtttatc ttgtttattt cgtagaaaaa caactcatgg tccaagaaaa
     4501 agacaagata tgttcattgc caggaggtga atggattgac gattaaatgg gaaaaatggc
     4561 tgtgtggcgt ttactccttt gtgatactaa gtgtaggtgc tccgatattt gtagtagcta
     4621 atcaattgca aaacagctac cttcttatcc taactattgg tgtcctatgc cttattgtct
     4681 gctgtattcc taaaaaatgg gtacgtttgc tgctttcttt gccagtaatg ataggttgtt
     4741 tgtttttgta ttttccttcg aagacatttt ccttattatg gatcttacag tttttttcgt
     4801 cagtcacaga ggaattcttc catctatccc aaggtaaact ttattatttg ccagaaaaga
     4861 cagctttttt tctcataatg ttgctgatct atttatttat tacattgacc gtggattacg
     4921 actatttgta cgcacccttt ctttctttga tggcttactt catgatgctt accgtttttc
     4981 gggaaaaaga tttactgtac gaaatgattg cggtagtaac tgttttgttc gtgtatctgg
     5041 cagcaaggca atttttctcc atgcggttgt tgtcgggaaa cactcgattc cagtcattga
     5101 ctacagttct gcttatttgt ttcttaacta ttagcgctat cttgccttta tatcttccga
     5161 aagtacacca atctctcgag gaaacgagtg aaccgatccg agaatatctt aatgatgaag
     5221 ggctttatga tacactccat gagtatcaat taaccggaag tgcaagaaca ggcttcagtg
     5281 agaatgatga acagcttggt ggacctttat atgataatgg cgaagttgtt tttacagcga
     5341 accaaaaagg aaatggctat tggaagatcg aaaataaaaa tcattacacc ggttctggat
     5401 ggatagaaga tcaggacgca cccatccaac caatccaaga attccctgtt gacatcacga
     5461 gctaccaaac cgttatggaa gacaaagaaa acattacatt gaccctaaaa aaacaagctt
     5521 tcttacctta tccttatgga aatactacct tgactgattt ttcattagct agtggacaaa
     5581 cgctttacta tttgcctgaa agccagcgat tcattcctgt cccgaatgaa tcgacacgtt
     5641 ctgcaacttt acaaacagaa aggttagttt ttacgagaga agaattaaaa agcagtcagt
     5701 taaaagctga tgatttagaa aatcagcaga caaatcttca attgccaaaa agtttgccta
     5761 aacgtattga ggacttggcg gtcgaattga ccaaaaatga agcaacttta attcgtaaag
     5821 tcgaagctgt cgaacagtat ttaaaaacaa gcggaaattt ccgctattcc aaaacggata
     5881 ccggacatac tccgaaagaa cacgattatg tggattattt cctctttgat tcaaaagtcg
     5941 gctattgtga caacttttca acttctatgg tcgtccttct tcgaacactt ggtatcccag
     6001 ctcgctggac aaaaggtttt acaaatgggc tcagaacagg cacagataat caagggaatg
     6061 aggaatacag cattctcaat agtcatgctc attcttggcc agaggtatac tttcctggat
     6121 ttggctggct tccatttgaa ccaacccctt catttgccaa tccaatgggt tcacaaccag
     6181 ttgctgaaac aaccgaaacc gtccagcctg ctatcgaaca accaaatgaa agcgaaaata
     6241 tggcagaaac tatttccagt gagagatctg aggtcattcc atcagaagaa acaacactca
     6301 caccagctta taaaatcgtc ttattcagcc ttggggtgtg tttatacgtc ttgttgttct
     6361 ttctattgtt attcagaaaa tctctgcgct ggacaagtta tcttatctat cttcattttt
     6421 ttgcttctac taatacgatt gcatatcaaa aacttcttaa ccatttggaa acattggtac
     6481 cgcgcaaacc cgcagaatct ttgcaggaat atagcctgcg aatagaacaa gaattcaagc
     6541 tagatctgcg tttcattcga ttaactactc aatatgaagc agaaatatat ggacgacaag
     6601 cagatccggt aaatttcgat aaaaaaacct atttagaaat tacgcatata ataagaaaaa
     6661 cggtatacaa aaaagttctg acaaaaggga gccgcttcaa aaaataagat aaaatttctg
     6721 gagaatctac ttctggaatg ccgagaacca gctgcttgag tatcgattat tcgaaaaaaa
     6781 ggttgtgaca cgttttttgt cacaaccttt tttcattatt atttgatttt caatgtcaaa
     6841 gcatttagag ctacaactac cgtacttaac gacatcaaga cagcaccaac tgctggactt
     6901 aatatgatac caattggcgc aagaattccg gctgctagcg gaattgcaag aatattgtaa
     6961 cctgcccccc accagaggtt ctggatcatt ttctttcgcg tttgcttggc tagatcaaga
     7021 aaatgcaaaa tatcttttgg atcgctgttt gtcaatacga catccgcaga atcgattgcg
     7081 atatctgtcc ctgcaccgat tgccatcccg attgaagcac gggctaaact tggcgcatca
     7141 ttgatcccat cacccaccat gattactttt ttcccttggt caaggtattt ctggacaaca
     7201 gcttctttat catctggtaa taaaccgcca taatattctt cgatccctaa ataatctgct
     7261 actgcttggg cagcgttttt attgtcacca gtaagcatga caggagtgat ttttctttct
     7321 ttcaatgttc ggataaattc ttttgcttct gtttttacta cgtcacctaa agcaacgatt
     7381 gcagctagat gattttctaa aatcaggaag ctgatggtat ttccttgttc ttggtaaggt
     7441 ttcaataatg cttgttctac gtttaatccg agacgctcaa cttctttttc attaactatt
     7501 ttcacttgtt ggtttttgac tgttgcctct agcccaactc ctgaaagatt ttttagattt
     7561 tcggcttgat aaggcttgat ttcatgttct ttcaaataat tcataatacc aacagccaat
     7621 ggatgattgg cattcgcttc caatgctcct aaatattgaa ggatttcatt tttattgaac
     7681 gcatcatcaa gtacttcgac acccgttaca gtaaattttc cttctgttag tgttcctgtt
     7741 ttgtccagca tgatcacatc tagatcattg gcttgctcca gtgcattgcg gtttttcaaa
     7801 agtaatccgt ttttagctgc tattgatgta gagcgagcaa caactaatgg gatagctaaa
     7861 cctagagcat gaggacaggc gatgataaag actgttacca tacgttctaa tgcattagga
     7921 agatctgtca agaacaacca ggcgatgaat gccaggatac ccacaattaa tgcgacataa
     7981 aacagccatt ttgccacttt gtcagataat gactctagct tggatttttc tccttgtgct
     8041 tttcgcacca tttccataac cttcgctaga taaccatttt caccagttcc agttacttcg
     8101 atttcgatcg ttccatcccc attgatagaa ccgccaatca ctttgtcatt ggcttgtttt
     8161 ttgattcctc ttgattcgcc agtcacagct gattcgtcaa caattgtttc acctttcaag
     8221 attacaccat ctgttggcat tttatcacca gaccggacga tcaaacgatc accttcgttt
     8281 acttctttca atgaaactgt ctcttctttt ccatctttcg tcaagcgttt tactgattct
     8341 ggcagtaatt ctgctagttt ttgtaaagca ttgctggcat tcgacacagc attcatttca
     8401 atccagtgac ctagtagcat aataacgatc aaagtagcca attcccagaa gaaatccatg
     8461 acgtgtgtat gtggattgag cagatttgcg ataaacgaat agacactata aatatatgca
     8521 actgtaatcc ccatcgcgat cagtgtcatc atagcaggac ttttttgttt caattccatc
     8581 ttagctccac ttaaaaatgg ctgaccgcca tagataaata gtatagttgc taagatcaat
     8641 acgagccaat cagaaccagg aaacgttact tgaaatggaa attccattcc catcattggt
     8701 gaaaaaagaa tgattgggat agctaggata agcgatagcc aaaatttttg tttgaaattt
     8761 cccatgtgca tggaatgatc catgccgcca tgatcgtgat ccatgtgcat cgaatggtcc
     8821 atttgtttgc tgtttgctat atctccatgg ttatgtccca tgtgcatgga atggtccatc
     8881 tggctatggt catgtttcat ctccatctgt ttttcatgag attctgtact ttctttgttt
     8941 actacttctt ttttatgttc atgtcccatg tgcatggaat ggtccatctg gctatggtca
     9001 tgtttcatct ccatctgttt ttcatgagat tctgtacttt ctttgtttac tacttctttt
     9061 ttatgttcat gttttttctc catatcgttc ccattcattt ttactccatc ccttctctta
     9121 ctttttcatg tgccgattta agctcaggga gttcaacaat acactgacgg aactaaacgc
     9181 catcgctcct cctgcaatga ttggattcaa aaagcctagt gcggcaaaag gaataccaat
     9241 cgtattatag acaaaagccc agaaaagatt ttgtttgatt tttctcaatg tcaccctaga
     9301 caactcgatt gtttgtgcaa tggatgccaa actgctactc atcagcgtca catcggctgt
     9361 ttccatcgcg atatccgttc cacttcccat tgccatacca acatcagcta atgctaaagc
     9421 cggtgcatca ttgattccat cgcctgccat accgactttt ttgccatctt tctgaagttt
     9481 ttctacgtag gctgctttat cctctggaag tacttcagca aagatatgct ttggatcaat
     9541 accaacttgt ttaccaatcg tttcggctgc cagtttgttg tctcctgtca gcataaaaac
     9601 atctaatcct ttattctgga gctgcttgat tgcttgtttg gcttctagtt tgatttgatc
     9661 agccacggca atcaacccga tcacttgctt ttcatcagct aaaaacatga ctgtttttcc
     9721 ctgctgttct aattctaacg cgtgttcttg gtattcatca aatgataggt tcaattcaat
     9781 taatcgttta cgtgtacccg caaaatagcg tactccgtta atcgtaccgc tgattccagc
     9841 acctgggtga gctgtaaaat caatcatatc gtatgttgct gcttcttgca gttttccgta
     9901 ttccacgatt gctttaccta gtggatgttc agaagcttgt tctaaagtat aaaaaataga
     9961 taggacttct ttagaaccga ctagatctgt aactttgggc tttccttctg taatcgtccc
    10021 agttttatcc aaaacaatgc tgtctaagtg agcagctgct tctaatgctt ctccgccttt
    10081 aattaaaatt ccatttcgtg caccaacacc cgttcctacc ataatagctg ttggagtcgc
    10141 taaacctaat gcacatggac acgcaatgac taatacagag acactatgga tcaatgcgag
    10201 ttgccaatca ccagtgatca aacctgtagc tatgagcgtg ataaacgcga tgactaatac
    10261 gatcggaaca aaaatccctg agatccgatc tgcgattttt tggattgggg ctttgctccc
    10321 ttgagcatct tccaccattt gaatgatttg cgctaatact gtctgcttgc cgacttgtgt
    10381 gacttccatg tgtagcagac cattcgtatt gattgtcccg ccaaaaagcg tgtcatccgg
    10441 attcttttct acaggaagat tttcaccagt aagcatactt tcatctatcg cactgcttcc
    10501 tgaaataatt cgaccatctg ctggaatctg ctcaccagga cggatgacta gttgatcacc
    10561 aacgactact tcttcaatcg ctaacgtttc ttctttcccg tttcttatca cttgggcggt
    10621 ttttgtttga agagacatca attgtttgat tgcattacct gttttcgttt ttgctgtatg
    10681 ttccaaatat ttgccgagca aaatcagcgt gatgatcata ctgctgcttt caaaataaag
    10741 atcttggggg tgtccacgga aaaatccgtt gtaaatgctc aatgcaaagg cagccgatgt
    10801 tccaattgct accaatacat ccatatttgg tgctttcgac ttgattgcat ggtacgcacc
    10861 tttataaaaa cgagcaccga cataaaattg gacaggagca gacagcacta actggacgat
    10921 tggaaaatga aaaaagtgaa caatcgccgc atggcttcct aacatcatag caatcattga
    10981 caacatcaac ggcaaagtca aaaccgtact caatataaga tcgaatagca tttttttcaa
    11041 atacgcttgc ttttcttctg caattttttg tttgtgggct tcatcgtaca aaattgcacc
    11101 atagccgatg ttttctacgc tttggattaa tttttcagtg gtcgtccctt catatttgac
    11161 acttgctttt tcagtggcca agttgactgt ggcattgacc acaccaggtt gtccgttcag
    11221 ctctttttcg atcctagcag aacaatttgc acaagtcata cctgtaatga cgaacgtatc
    11281 cattttggtt tctgctgttg ccatcaaatc acctctgctt tataacccaa tccattgatt
    11341 gcttgacaaa tcttttcgga ttgaactttt gtttcatcaa acttgaccgt accgtttgct
    11401 tttttcaaat ttactttcac tttttgcacg ccgtcaagtg cgcttactgt ttcttctact
    11461 cttgctgcac aatgattgca gctcatacct tcgattgaaa attgttgttt cattttttct
    11521 tcctcctatt gatgttgttt acattcacat tgacctggga tacagttaca ttcgatcgta
    11581 tctactggtt gcttttgttc cagttgtttc aaaatctcat tgatatcttc ttgagtcaaa
    11641 gtggcttctt ctactagatc cgcaatcgtc tctccaatcc tttttgcaca gatatgggaa
    11701 aaaagatttt ccgtcgcact gcgaactgtt tccatctccg agacagctgg atgataaatg
    11761 aatttttttc cttcttgttc tgtccagatc acttcttttt ttaccaaacg acccagcaaa
    11821 gttttgatcg ttgctggttt ccaatccatc gaatcagcta agatctgcgt gatttcttgg
    11881 gctgtcgtct gtccaagtgt ccaaataaca cgcatgatct cccactctga atcactaatc
    11941 tttactggcg ttttgacttt ttccatttat ttcacacctt tcgtttacaa atgtaatcat
    12001 taacttatga atacagatta cacttgtaaa caaaaactgt caattatttt tgctctctat
    12061 tttcaattta gttaaaaatt cttgtttctc tcgtcttgtt ttaaggatga tcagtttatt
    12121 tcttgcatta gctacttgga tcagctgctg tatttttggt tcattgtttc cttcaaaatg
    12181 ccagataaaa gataaaaatt ctaagtattt cctgtttagt ttctccgaaa atgattcagg
    12241 catatctggc cgagattttt tgtttatctt tctttttaga gaacgccaaa ctactcggta
    12301 gatggcgaga taacgcggca ctttaagcca aatgatctta tctgcttctt taatcctttc
    12361 ctctaacgta gaagtataat ttccttcaac gatccatgac ggattagata ccataaacga
    12421 ttgctgttct tgcaaaaacc acttttttgc ctgaatgcgg aaagccggtg atttctttga
    12481 tcttccttgc gagggacgat tttcccgacc cactttgtcc aatcacgatg atcttcattc
    12541 ttctccctca cttctctttg gaatttggtt cgatcatacc acttataacg ccgcaaaaaa
    12601 a
//
LOCUS       DADLIO010000077        12514 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.080, whole genome shotgun sequence.
ACCESSION   DADLIO010000077 DADLIO010000000
VERSION     DADLIO010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12514
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.080"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            51..788
                     /locus_tag="JOX41_002339"
     CDS             51..788
                     /locus_tag="JOX41_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAY6450048.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            802..1617
                     /locus_tag="JOX41_002340"
     CDS             802..1617
                     /locus_tag="JOX41_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAY6450049.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            1630..2277
                     /locus_tag="JOX41_002341"
     CDS             1630..2277
                     /locus_tag="JOX41_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAY6450050.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            2293..2949
                     /locus_tag="JOX41_002342"
     CDS             2293..2949
                     /locus_tag="JOX41_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAY6450051.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            3111..3932
                     /gene="racE"
                     /locus_tag="JOX41_002343"
     CDS             3111..3932
                     /gene="racE"
                     /locus_tag="JOX41_002343"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HAY6450052.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            3935..5290
                     /gene="rph"
                     /locus_tag="JOX41_002344"
     CDS             3935..5290
                     /gene="rph"
                     /locus_tag="JOX41_002344"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HAY6450053.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            5291..5809
                     /locus_tag="JOX41_002345"
     CDS             5291..5809
                     /locus_tag="JOX41_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAY6450054.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            5916..6416
                     /locus_tag="JOX41_002346"
     CDS             5916..6416
                     /locus_tag="JOX41_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAY6450055.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(6696..7616)
                     /locus_tag="JOX41_002347"
     CDS             complement(6696..7616)
                     /locus_tag="JOX41_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HAY6450056.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            7781..8794
                     /locus_tag="JOX41_002348"
     CDS             7781..8794
                     /locus_tag="JOX41_002348"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HAY6450057.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(8904..9659)
                     /gene="fabI"
                     /locus_tag="JOX41_002349"
     CDS             complement(8904..9659)
                     /gene="fabI"
                     /locus_tag="JOX41_002349"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HAY6450058.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            9879..10319
                     /gene="fabZ"
                     /locus_tag="JOX41_002350"
     CDS             9879..10319
                     /gene="fabZ"
                     /locus_tag="JOX41_002350"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HAY6450059.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(10434..11195)
                     /locus_tag="JOX41_002351"
     CDS             complement(10434..11195)
                     /locus_tag="JOX41_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAY6450060.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            11384..12478
                     /locus_tag="JOX41_002352"
     CDS             11384..12478
                     /locus_tag="JOX41_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAY6450061.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
BASE COUNT         4042 a         2173 c         2637 g         3662 t
ORIGIN      
        1 tatacatctt taaaagaaat cttactaaat aataatggga gtgtaattct atggcaatga
       61 ttaaatttga tcacgtggat aaatattatg gcaagttcca cgcattaaaa aatatcaatc
      121 tcgaattcga gaaaggagaa gttgtcgttg tcattggtcc ttctggttca ggaaagagca
      181 cgatgcttcg ctgtatcaat ggattagaga cgatctcttc aggtaagctg ctgattaatg
      241 atactgactt gcatgataaa aagacaaaac tgacagaagt ccgaaaaaac atcggcatgg
      301 ttttccaaca tttcaatttg tacccaaata aaactgttct ggaaaacatc aaattagcac
      361 caatcaaagt gttgaagcaa gaccaggcaa ctgcagtcaa aaacgcggag aaatttttga
      421 aaactgtcaa tatgttagat aagaaagatt cttatccttc catgttatcc gggggacaac
      481 agcaacgggt ggcaatcgcc agaggtttag cgatgaatcc tgagatgctg ctgtttgatg
      541 aacctacttc tgctttggat ccggaaatga ttggtgatgt attagacgtt atgaaaaaat
      601 tggctcatga cggtatgtca atgattgtcg tgacacatga aatgggcttt gccaaagaag
      661 tggcggatcg tgttatcttc atggctgatg gagaagtatt ggaagacagc agaaatgtga
      721 gagacttttt cgaaaatcca aatgaagtcc gagcacagca atttatcagt aaagttatca
      781 atcattgata ggaggaaaaa gatgcgcagg ttaaaaaaaa tacgcctgat tttcctttta
      841 ggcattgctt ttcttgcact agccggatgt aaaggaaatg ggttggcaaa tgaagatatt
      901 ttagagcgaa gcaaatctac caatgaaatc atctggggtg tcaagtatga tactcgatta
      961 tttggaatga tggatattga gagcagaact gtacaaggat ttgatgtaga tattgcaaaa
     1021 gcaatcacta aaaagatcct tggtgacaat ggaaaaacag aatttgttga agtcacttct
     1081 aaaactcgga ttccattatt gaaaaacgga aatatcgatg caattattgc aacgatgacg
     1141 atcacagatg aacgaaaaaa acaggttgac ttttcagatg tctatttcga tgctggccaa
     1201 gctttgttgg taaagaaagg aagccaaatc aaaagtgtag atgatttgaa tgcttctaca
     1261 acggttctag cagtcaaagg ttctacatcg gctgcgaata tccgacagca tgcaccagat
     1321 gcaaaaattt tagaattaga aaactatgca gaagcattta ctgctttaca atctggtcag
     1381 ggagacgcga tgactacgga taatgcgatt ttgttaggga ttgcagatga aaatccagag
     1441 tatgagttag ttggtggaac gtttactaat gagccttacg ggattgcgat caacaaaggg
     1501 caagaaaact tcttgaaagc tgttaaccaa gcgctagagg aaatgcatgc agatggcaca
     1561 tacgataaaa tctatcaaaa atggtttcca aatgaaactg aaggaaaagt agagtaaggg
     1621 ggagaggcaa tgagcgaatt gatacaaact tatggaccaa tctttgtcga cgggttcaag
     1681 atcacattgt tttcgagtgt cttagcactt gtgtttagtt tgattatcgg aacgttaatg
     1741 gcaatcttcc aattatcaaa gaataaagta gtgagcgcct tagcaaaggc atatgtagaa
     1801 ttttttagaa acattccatt attaatcatc gtgatgtttt tttatgttgt cgtaccgatt
     1861 tattggttta atctagatgg attccaagca ggtacgattg gattaacgat ctatacatct
     1921 gcttttattg ctgaaacagt acgttcaggg attcaaaccg taccaaaagg tcaaacagaa
     1981 gcaggactat cttctggttt tacctattca gaaatcatgc gttatattgt tttaccgcaa
     2041 gcattcaaaa tcgttatccc gccattaggc aaccaattta tcaacctcgt aaaaaactca
     2101 tctattttag caatcgtagc tggtttagat ttgatgtatc aaggagactt gatcgctagt
     2161 gaaacattca ataccttcga tacgtatatc atcgttgggt tattttactt agttatcacg
     2221 ctaccgttat cttacttaat ggtttatctt gagaaaaaat gggcggttcg ttcatagaag
     2281 gaggggaaat acatggattt tagcggcgct ttttcatgga tgaatatccg ttttttattg
     2341 gaaggattaa aggttactgt tgaagtttca ttgttttcga tcatttttag tttcttgatc
     2401 ggtggtctga caggtgtgat tcgttttgcg aatatccctt tcttttccaa aatccttggt
     2461 gtagtgattg atattatacg gaatcttcca ttattattga tcattttctt cacttacttt
     2521 gccttacctc aaatcggcat tcagatgaac atcttctggt ccgctgtcgc agcattaacg
     2581 atttttgagt cagctatgtt gtcggaaatt ttccgagctg gactcaatgc tgttccaaaa
     2641 ggacagatgg aagcaggatt atcaacggga ctgacttatg tagaatcgat gcgaacgatc
     2701 gtgttaccgc aagcatttaa atcaatgatc ccggcaattg tgagccaatt gatttcactg
     2761 atcaaagata cttcattagc agtaatcatt tctttacctg aactttctca tcaggcacgt
     2821 attatttatg gacagaacac caattatgtg cttccgatgt tcatcatcat gacacttatg
     2881 tacttcgtgg tatgttacgc gctttctctg ctttccggtt acttggaaaa gagacggtac
     2941 agttattaat agatgattct tttagcggtt gtggcaaact aaagtcacaa ccgcttttcc
     3001 tctttccatt cgaaaaaaag agatttcgat tgttttaagc aagtaagagc acttgaaaat
     3061 tcacgctaaa aagtacacaa tagggaggat agaatttatt gaaaaaaagg atgatacgat
     3121 tgacagataa tcgccctatc ggatttattg attcaggtgt cggcggcttg actgtagtaa
     3181 aagaagccct gaaacaatta ccgaatgaaa atattttatt tgtaggagac acagcacgct
     3241 gcccatatgg ccctagaccc gcggaacagg taatccagta tacttgggaa atgacggatt
     3301 atctggtgga gcaaggaatc aagatgctgg tgatcgcctg caataccgca actgcggtgg
     3361 ctttagaaga aatcaaagct gctctttcta ttccagtcat cggtgtgatc cttcccggta
     3421 ctagagcggc agtaaaaaaa acacaaaata aacaagttgg cattatcggt acgattggta
     3481 cggtaaaaag tcaagcttat gaaaaagcac tgaaagagaa agtaccagaa ttgactgtga
     3541 caagtcttgc ttgtcccaaa tttgtttcag ttgtcgaaag taatgaatac cattcatcgg
     3601 tggcgaaaaa aattgtggca gaaacattag ctcctttaac cactaaaaaa atcgatacat
     3661 tgattttggg atgcacccat tatccattat tacgccccat cattcaaaat gtaatgggag
     3721 aaaatgttca actgatcgat tctggagcag aaacagtagg tgaagtatct atgctgttag
     3781 attatttcaa tttgagcaat tcaccgcaaa atggtcggac attatgccag ttttatacaa
     3841 ctggctctgc caaacttttc gaggaaatag ctgaagactg gcttggaatc ggacacttaa
     3901 atgtagaaca tatcgaattg ggaggaaaat aaggatgcgt catgacggga gaaaagccca
     3961 agagcttcgc aaactggagc ttcaaacaaa tgttttcaaa tatccagaag gatcggtagt
     4021 gatccgtttt ggtgatacaa cagttatttg ttctgcaaca atagaaaatt ctgttccccc
     4081 ttttttgaga gaaacaggaa caggatgggt gacagcagaa tatagtatgc tgcctcgagc
     4141 aacgagtacg agaaatcgta gagaaagcag caaagggaaa ctttctggta gaacaatgga
     4201 aatccagcgt cttattggtc gttccttgcg tgcagtagta gacttggaaa aattaggaga
     4261 acgtagtatc atcgtagact gcgatgtgat ccaagcggat ggcggtacta gaacagcaag
     4321 tatcactggg gcatttgtgg cattgaaatt agccattgaa aaacttttaa gagaaaaaga
     4381 attgtcagaa gatccaataa aagaacatct tgctgcagtt agcgtaggaa tcttaccaga
     4441 tgggacttgc gtcacagatt tggattacca agaagattcc gcagcacttg tagacatgaa
     4501 tcttgtaatg acagaatctg gaaaattcgt ggagattcaa ggaactggag aagaagcaac
     4561 gtttgatggt gaacagttga atgaaatgct cttttttgga aaaaacgcga ttgaagattt
     4621 gatcaaagag caaaaacatg ctttgctaac agagtttgct caaaatgatg agcggataga
     4681 agaaacaaaa acaatcatca ttgcgacaag aaatccagga aaagcagaag agtttcgaaa
     4741 tatgttcaaa gaagcgggat atcatgtaaa aacattactt gactatcctg aattgccaga
     4801 tgtggaagaa actggcagca catttgaaga aaatgcccga ttaaaagcag aaacgattgc
     4861 acaattgctt gatcagccag tcttagcaga tgattcaggt ttgaaagtgg atgctttagg
     4921 cggtatgcca ggaatctatt ctgcacgttt tgcaggggaa caaaaaagtg atgcggggaa
     4981 taacgccaaa ttattatatg aattgacaga tgtgccggat gaaaaaagaa cagcacaatt
     5041 ccattgtacg ttagtattcg cggcacccaa aaaagacagc cttgtagtag aagcggaatg
     5101 gcccggtcga gtagcccgta taccatctgg cgaaaatggc tttgggtatg atcctttatt
     5161 tatcccagaa ggtaagaaac aaacagcagc agaattatcg agcgaagaaa aaaacaagat
     5221 cagtcatcgg gctcaagcaa tgaaaaaatt gagtgccgag tggaaacaat ggctggaagg
     5281 agagagatag atgcggtatt tagtagtaag tgataatcat ggagacagag atatcctcgt
     5341 tgacttagta gatcgttatc gttctgaagt ggatatcttt ttccattgtg gtgattcgga
     5401 attagaagct tctgacccat tatgggatac attccaagtg gttcaaggta attgtgatta
     5461 tggaccagga ttcgaacaga aaaaagtgat ccaaactggt caggatacag tattcatgac
     5521 tcacggtcat ttatcgaatg tccgatttgg tttgacacag ttagcaatcg aagctcgagc
     5581 tgcaactgcc gatatggtgt tttttggtca tacccatcaa ataggctgtg agatggatca
     5641 gaaaatcctg tttttgaatc ctggtagcat ttctcagcct agaggcccga tccaaatccc
     5701 atcatatgct cttatcgaaa gtttagatga ccaaatttct gttcaatact ataaccgtgc
     5761 ccatcaggca gttgaagagt tggccttttc tttttcgaga gagcgctgaa taaaaaaact
     5821 ctaattttta ataaaaataa gctttatttt atgaattttg catccggttt cggtaaaata
     5881 gtagtgttga atgaaataga aatggaggcc atcagatgat tggacctata gtaagagaaa
     5941 tgctgctgga aaatcaggaa acgtttttga ttcctgcaga aaatgtggca aatgttatgt
     6001 atcatcatcc attgtcccat ggtttacttg tgttatcgaa ggtcggttat tccaaaattc
     6061 ctgtattagg aaaagatgat cactttgtag gactagtaag tttatcagat gtggtcaata
     6121 aaatgattga cttgcaaaca atcagcatgg acccgttaga aggactaacg gttgctgatg
     6181 tgacagaaac agatgttccg acaattgatg aaaattggga actagaagaa gtactccatt
     6241 tgttagtcga ttcgcctttt ttaccggttg tcacagaaga tcggattttc aaaggaatca
     6301 ttacaagaaa agagctgctt aaagccgtaa acttcatggt gcatgaatta gaacgtcgta
     6361 atatattgtc tccgaaaatc gaagaattaa aagaacaaat cgatatcgtg agctaaagaa
     6421 cgagaaacta aaagataatc aaaaaataag tagaaaaaac agcgtaccag ttttgacttt
     6481 atcttgaaaa agaggctggg acaaaagcgt ttaactccaa gaaataagaa ggaattcacg
     6541 aaaattgctt ttcaaatttt tgtgaatttc agcttatttc cgaaggagtt gcttctgctt
     6601 ccgccgttta tacgtgttta gagcgtggga caaaagtgtt ctttactttt gtcccacgct
     6661 ctttttagtg agattcgttg catcgtttgt ccaaattatt ttccgacagc aattggactg
     6721 ttcggaatcg tgaaaccaga agctgtcaat tctttgacat aggagctcaa gaactcttct
     6781 tttaaggcat attgttttcc gttcaatgcg tagcagaccg tacgaatcgc aaaattgctg
     6841 tttccaagat ccactaatcc aaagatagaa ggttcagttt ggagctcttc ttggtatttt
     6901 tcagctaatg tacgatttac tcgatcaatg atctcataga ttttgtcata tccttcttca
     6961 ggaacaatcc gaatatctaa aagtacttgc atatttgcac gagagagatt gctgatcgtg
     7021 gtgatgtttc gattcgggat gaaatggaca gtaccatccg ttgctttcag ctgaagggta
     7081 cggataccaa cagatacgac ggttccttca atcgttaagt ttgctagctt gatgtagtcc
     7141 ccaacatcca tctgttgttc catgataata aaaaatccgg taataacatc actcatgaac
     7201 ccttgggcac caagaccgat tgccacacct gcaattccgg caccagccaa aagtgatccg
     7261 atcggcacac cgatagcaga taaaattgca tagataaaaa agaaaccaag ggtataatga
     7321 aaaatagtat ttaaaagact atgtaaagtc tttaagcggc tctcgtttag aatggctttt
     7381 ttagaatact gattaaaaga cttatcaatc agatattttc ccacacggtg aagaatccaa
     7441 aaaaggacga tcaaaaaaat cagatataaa cttttttgga taaaggcagc caaaatggcg
     7501 tcccaatcaa tcccgtccca aaaccgctga aacgcattta ctttgctgac agcttgatct
     7561 gtcaatgtct cgccagaaga gtctgtcgta ccggcagttg ctaataatga aaacataaaa
     7621 tcctcttttc taaaatttga ttctttctgt attgtaccaa gaagttttca aaaaaggaaa
     7681 tagcaaaaat aactataatg aaggaaaaaa gctgaaaata aaatgacaaa taatatggat
     7741 aatgataaaa tgtggagaaa ataacgaagg tggtaagtat atgcaaatcg attggaacaa
     7801 tctaggtttt tcttatatca aaactccttg gcgttttatt gccaaatgga aagacggaca
     7861 atgggaagaa ggagaattga cagaagataa ttacctgacg attcatgaag gctctccagc
     7921 gcttcattat ggtcagcaat gttttgaagg tctaaaagct tatcgtcgaa aagacggcaa
     7981 ggtcaatctc tttcgacctg aacaaaatag tcgacggatg aatcaaagtg ctagacgatt
     8041 gctgatgcca atggtccctg aaaagatgtt cgttgatgct gtcaagcaag tggtaaaagc
     8101 aaatgaagat tttgtgccgc cctatggaac aggcgctaca ttatacttgc gccctttact
     8161 gattggggtc ggtgaaaaca ttggtgtcca tccagctcca gaatatttat ttgtcgtctt
     8221 ctgtacgcca gtaggagcgt atttcaaagg tggactaaaa ccaacgaatt ttattgtatc
     8281 tgattacgat cgtgctgctc ctaaggggac tggtgcagca aaagtcggcg gaaattacgc
     8341 agcgagttta cttccaggaa cagaagcaaa agaactggat tactcagatt gtgtttatct
     8401 tgatccagcc acacatacga aaatcgaaga agtaggtgca gcaaatttct ttggaattac
     8461 aaaagacgga aaattcatca ctccgcaatc gccctctatc ttaccaagta tcacgaaata
     8521 ttccttgttg cagttagctg aagaacgact aggactgcaa gcaattgaag gagatatttt
     8581 cattgatgat ctagatcaat ttgcagaagc tggtgcatgt ggtacagcgg ctgttatttc
     8641 tccaatcggt gggatttatc acaataacaa tcttcatgta ttttatagtg aaacggaagt
     8701 aggaccagta acaaaacggt tgtatgatga attgacaggt attcaatttg gagacataga
     8761 agcaccagaa ggctggattg aagtcgtgga ataatttcaa agtaatgagt tgaaaaaaac
     8821 gtaaaaagaa aaaatcagga agagacttta aaaagttttt tcctgatttt tatatgtttt
     8881 actttaaaga atgcaacaaa agtttatgaa agatggacac ctttgtcaac gtagataata
     8941 tcaccgatga ttccgctgga aagtgggctg attaagaaag cacaagcatt accgacttct
     9001 tcgatcgtca caccttgctg atcaggcgta cgagattcag ataactggat cagtttttga
     9061 tagtctttaa cacctgtgac agctaatgtt ttgattgccc cagctgagat tccattgacc
     9121 cgaattcctt taggcgagaa ctcagctgcc aaataacgga tagcagcttc aagagaagct
     9181 ttcgcaatac ccatcatgtt ataattcggg attgcgcgtt ctgaacctag ataagtcatg
     9241 ctaacgatcc cgctgtttgg tgcaagaaac ggttgtgcgt attttgatac agcaattaaa
     9301 gagtagctgc tgatatcttg agctaattga tagccgtctc tggaaatatc agacacattt
     9361 ccggacaatt cttctttgtt ggcgtaagca actgcatgga caaggccgtg gatctcccca
     9421 gcatattcac cgatggcatt cattgctttt tcgatgcttt cgtcgctaga aacatcacat
     9481 tctacagtga atgcttcttc gccgaccaat ttgactaatg attttttcat tcgttcattt
     9541 tggtaagtat agataatttc tgccccttgt ttcaacattg cttcagcaca accccaagca
     9601 atgctttttt tgttagcgac gcccataatg acgatttttt ttccttctag aaatgacata
     9661 atgactctcc tttgtttctg ataaaaattt gatagtcgta aaaaaataga gaataatagc
     9721 taaaataact tcttgatttc ttaattatta gtcaaaatgt tttgattgtc aaactatttt
     9781 ttcttaaatt aaaaaaagat tgctaaatat ttaggaatat gatactttga tagtcaaagt
     9841 aatgaaaatg gcaattgcct gaaagaagga gtttaattat gtcttacgta ttatctgcta
     9901 ctgaagtaat ggaattgatt cctaatcgtt atcctatttg ttatattgat tatgtagata
     9961 ctttagaacc aggaaaaaag atcgttgcga caaaaaatgt aacaatcaat gaagattttt
    10021 tccaaggtca ctttcctgac aatccagtga tgccgggtgc gttgattcta gaaacactgg
    10081 cacaagcagg ttcgatactt atcctaaaat cagaagagtt tctaggaaaa agagcttata
    10141 tcggtgggat caataaggcc aaattccgtc aaaaagttgt tccaggagat gtgctgaaat
    10201 gtcattttga aatcaccaaa atgaagggat cagtcggtac agcgttatct gcagcatatg
    10261 tagatgataa aaaagtctgt gagtgcgagt tcacgttcat cgtcaaccaa aatgcttgac
    10321 tataaaacct gatatagcaa aacaaaagga agcttacttg ctttttatgt aaaaagaaga
    10381 cgcctgaatc ctagcatacg ttgtcatcta tgcaggattc agacgttatt tttttatttt
    10441 tgttttgctt cttgcagtat attgatttta tcgattttta cttcttcttt tggtttgtct
    10501 gaactatctg tttcgatatt tgcaatagca tccacgacat ccattccttc aatcacttgg
    10561 ccgaagacag tataatggcc atctagtgaa ggataaccgc cgtttttata agcgtcgatg
    10621 attgcttgag gatagtcgtc ttttaaaaga ccatcatgca tatcatctgt attttgaacg
    10681 ataaagaact ggctgccgtt actgttagga tcttgtgagc gagccataga taacgcacct
    10741 cttatattat aaaggtggtt gttgatctct gtttcaaatc cttctcccca aatgctttcc
    10801 cctccagtgc catcgccttt aggatcgcca ccttggatca tgaaatcttt gatgacgcga
    10861 tggaaagtca gtccgttgta gtaaccgtct tttgcatgtg tcataaagtt ttcaaccgct
    10921 tttggtgcgt gttcgggaaa taatttgatt ttgattgtgc ctttattcgt caccatttcg
    10981 accagatctt cattttcggc gacatctttc gtcaattgtg gtaattccaa tgcgttcaaa
    11041 tcgacgctac tggcagtcgt gctttccgca gtagatgtac tttttgaact ttctgtagac
    11101 gaactagaag aagtcgtgtt gtttgcagaa caaccagcag caaacagcaa tgctgctgct
    11161 aaactaatac ttaaaataac tttatttttc ttcataactg ttcctttcca atttactatt
    11221 ttgttatctt taatgataac aaaatagagg gaaaatacct acttaaatta ttggaattta
    11281 tcatttattt taaaagaaaa agaaaaggtg tagaccattt actttgtgtt tgctataatg
    11341 taagtggata caaaaacgaa aagatgcagg aggaaatggt aatatgggaa aattaggaat
    11401 ctcgatttat ccagaacggt caacatttga aaaggacaaa gcgtacttgg atttagctca
    11461 taagtatggg tataaacggg tttttaccag tttgctgcag atcaatgatg ataaagaaaa
    11521 agttctttca gaatttaaag aagtagttga ttacgcgaat agcctaggca tggaagtaat
    11581 ggttgatatc aatccagcgt tatttgaaca gttggagatt tcttacgatg acttatcttt
    11641 tttccataag atgggtgcct acggggtccg cttagatatc ggattcacag gagcagaaga
    11701 agcaaaaatg acgcgcaatc cttttggtat caaaatcgag atcaatatga gttcgggcac
    11761 gaattacgtt gacaacatca tgagttattc gccaaacacg gataatttat taggttctca
    11821 taatttttat cctcatcgat actctggttt aggatacgaa cactttgttt tttgttcaga
    11881 aaaattcaga aaatataatt tgaatacgat ggcattcgtc aattcgcaat ctgctgagtt
    11941 tggcccttgg cctacgcaag atggcttgtg cacgctggaa gaccaccgag atcttgaaat
    12001 tgcgacacaa gtgaagcatt taatccttac aggattgatt gatgatattt ctattggaaa
    12061 tgcgtacgca agtgaagaag aattgaaaga aatggcagaa gcatttaacg cggattatcc
    12121 aacattgaaa gtagatacgg aagaaggtat tacagaaaac gaacgaatct gcttgtttga
    12181 taaccttcat agttatcgag gggatcgctc agaatatatc cttcgttcaa cgatgactcg
    12241 tgtatactac aaagataaag atttcccgcc tcataatacg cgagatatgc atcatgggga
    12301 tgtactgatt gacaatgaag ggtacggtca atacaaagga gaaacacaaa tcgccttgaa
    12361 ggatatgaaa aacgacggac gtgtcaatgt tgtaggaaga atctccgatg acgaattatt
    12421 cctccttgac tttttgaaac catggtcaag ctttaaatta attgaaaata aaaaatagat
    12481 aattagttat tgcagaaata atccgctaga aata
//
LOCUS       DADLIO010000078        12271 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.081, whole genome shotgun sequence.
ACCESSION   DADLIO010000078 DADLIO010000000
VERSION     DADLIO010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12271
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.081"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(92..649)
                     /gene="frr"
                     /locus_tag="JOX41_002353"
     CDS             complement(92..649)
                     /gene="frr"
                     /locus_tag="JOX41_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HAY6450062.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(652..1374)
                     /locus_tag="JOX41_002354"
     CDS             complement(652..1374)
                     /locus_tag="JOX41_002354"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010761216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HAY6450063.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(1510..2391)
                     /locus_tag="JOX41_002355"
     CDS             complement(1510..2391)
                     /locus_tag="JOX41_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HAY6450064.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(2490..3272)
                     /gene="rpsB"
                     /locus_tag="JOX41_002356"
     CDS             complement(2490..3272)
                     /gene="rpsB"
                     /locus_tag="JOX41_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HAY6450065.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            3631..4110
                     /locus_tag="JOX41_002357"
     CDS             3631..4110
                     /locus_tag="JOX41_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HAY6450066.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            4327..5418
                     /gene="phnW"
                     /locus_tag="JOX41_002358"
     CDS             4327..5418
                     /gene="phnW"
                     /locus_tag="JOX41_002358"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HAY6450067.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            5411..5539
                     /locus_tag="JOX41_002359"
     CDS             5411..5539
                     /locus_tag="JOX41_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HAY6450068.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGTQLTDKEIR"
     gene            5543..6088
                     /locus_tag="JOX41_002360"
     CDS             5543..6088
                     /locus_tag="JOX41_002360"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HAY6450069.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(6542..8233)
                     /locus_tag="JOX41_002361"
     CDS             complement(6542..8233)
                     /locus_tag="JOX41_002361"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HAY6450070.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(8653..9600)
                     /gene="arcC"
                     /locus_tag="JOX41_002362"
     CDS             complement(8653..9600)
                     /gene="arcC"
                     /locus_tag="JOX41_002362"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HAY6450071.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(9715..10734)
                     /gene="argF"
                     /locus_tag="JOX41_002363"
     CDS             complement(9715..10734)
                     /gene="argF"
                     /locus_tag="JOX41_002363"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HAY6450072.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(10825..12054)
                     /gene="arcA"
                     /locus_tag="JOX41_002364"
     CDS             complement(10825..12054)
                     /gene="arcA"
                     /locus_tag="JOX41_002364"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HAY6450073.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
BASE COUNT         3367 a         2535 c         2206 g         4163 t
ORIGIN      
        1 taattttttc tttttttaat ttttaaataa aagaaatata aataaaaaca gaggaagcgg
       61 aatgatccgc ccctctgttt ttatgatttt attaaacttc caataattct ttttctttat
      121 cagcagcgat cttatctact tctttgatgc tgttatctgt caatgtttgt acgtcttttt
      181 ctaatccgcg caaatcatct tcggtaatat caccattttt ttgttgtttt ttatattcat
      241 cgatcgcatc acgacggatg ttacgaatcg cgatttttgc attttctgct tcttttttca
      301 catctttagc taattctttt ctgcgttctt ctgtcagttg cgggataact aagcgaatga
      361 catttccatc attggttgga ctgattccga tatcacttgc cataatagct ttttcaacat
      421 cttgaagaat gctcttgtca aaaggtgtga tcattaaaac acgtgcttct ggaatttgga
      481 ttgatgccat ttggttcaat ggtgttggcg caccgtagta gttcacagta atacggtcca
      541 aaaggctagc gttcgcacgg cctgcgcgga tttgcccaag ttcacgttga agattttgtg
      601 ctgctttttt cattttttct tttgcttctg tcataattgc atctgccatt tttatttccc
      661 ccttacagtt gttccgatat tttcgcctaa gattgcacgg cgaatatttc cgtgttcatt
      721 taaattgaag acaagcagtg gaatatcatt atccatgctt agtgaacttg cagttgaatc
      781 catgacttgt aatcctttgg caataacttc cagatgagtc agttcttcaa attttactgc
      841 atttgcatct actttcggat cagcagaata aacaccgtct acattgtttt tagccatcag
      901 gataacatct gcgccgattt ctgccgcgcg taatgctgct gttgtgtctg tcgagaagta
      961 cgggttgccg gtaccgcctg caaagataac gatccgtcct ttttctaaat gacgttctgc
     1021 tttacggcga atatatggct ctgcgatttg acgcatttca atcgaagttt gcacgcgtgt
     1081 cggtacaccc acgttttcca acgtatcctg taaagctaag gcattcataa ctgtagctaa
     1141 catacccatg taatcagctt gagcacgttc catgcccatt tgtgctccga tttgtccgcg
     1201 ccagatattt ccgccgccca caacgattgc catttcaacg cccagctcgt gaacttcttt
     1261 gatttcttgg atgatttctt tgattactgg tggtttgatt ccaaatcctg cgtccccagc
     1321 taaagcttct ccactcaatt ttaagactac acgctgatat ttcggtgtga ccatgttcat
     1381 tcctccaata ttttctattg ccattttacc atacttagat gatttcgaca ctctaagact
     1441 ggtttttctt gttttgctta aaaaaaggga gcgcacaaac cgtgcgttcc cgtctgttat
     1501 tcaacagaat tattttttca cttggctcat aacttcttct acaaagttat cttcgcgttt
     1561 ttcgatacct tcgccaactt cgaaacgtac gaatgtttta acagttgcgc cttttgatgc
     1621 aacgtatttt tcaacagtca tatcaggatc tttaacgaat ggttggtcca ccaaagcgat
     1681 ttctgctttg aatttcttca agcgtccttc taccattttt tcaacgatat tcgctggttt
     1741 gccttcgttc aatgcttgtt ctgtaagaac agttttttca tgttctaatt cagcttctgg
     1801 aatttgtgat tcgtttacat aacgaggatt gatagctgct acgtgcatag ctacgtctct
     1861 tgcaactgtt tcgtcagttg ttccatctag aacagtcaat acggcaatac gtccgcccat
     1921 atgcaagtat ccaccaaatg cagcattgtc gtctttttct acaacttcaa agcgacggaa
     1981 gctgattttt tctccgataa cttgagttgc ttcgatcaag tcagattcaa ttgtaccttt
     2041 atctgttttg attttcattg cagcttccat gtctgctggt ttgttttcag caacaagttc
     2101 tgcaatttct tttactaaat cttggaacat ttcgttttta gaaacaaagt ctgtttctga
     2161 gtttacttca acgattgctg cagtgttacc tttcacagca actgaagcca atccttcagc
     2221 tgcaatgcgg tcatttttct tcgcagcctt tgccattcct ttttcacgta aaagatcaac
     2281 tgctttttcc atgtcgcctt ctacttcaac taatgctttt ttcgcatcca tcattcctac
     2341 gccagtcatt tcgcgtagtt cttttaccat tttagctgta acgtctgcca tgtttaactc
     2401 ctcctgtgtg tttttctttt taaaaaaagc tgcttcaaag gagagtgagg cttgtcgccc
     2461 agcctttgaa acagctccat cattcaaaat tattctgctg aagaattgtc gccttcaaca
     2521 acatctacga tttcttcgat tgatgttgct gtgttttctt ctgtgaaatc ttcttcaact
     2581 acttgatctt caccttggtt tccttcgatg aaagcatcag ccatttttga agtaatcaat
     2641 ttaacggcac gaattgcatc gtcgtttgaa gggattacta cgtcgatttc atctggatcg
     2701 cagtttgtat caaccatagc tacgattggg atatttaatt tgtgtgcttc ttgaacagca
     2761 atacgttctt tacgtgggtc aacgatgtac attacatctg ggattcttgg catatcagcg
     2821 ataccgccta agaatttttc aagacgttca cgttctttgt tcaaaccagc aacttctttt
     2881 ttaggtagaa cttcaaaagt tccatcttct tccattgcat tgatttgttt caaacggctg
     2941 atacgttttt ggatagtatc ccagtttgtc aatgttccgc ctaaccaacg atggttaacg
     3001 aagtattgtc ctgcacgagt tgcttcttct ttgattgctt cttgtgcttg tttttttgta
     3061 cctacgaata atgctacgcc gccttcttca gcaacgctct tcatgtaatc ataagctgca
     3121 tctactaatt taactgtttt ttgcaagtca atgatgtaga ttccgtttct ttctgtgaag
     3181 atatatttct tcatttttgg attccagcga cgagtttggt gaccaaagtg tacgccggct
     3241 tctagtaatt gtttcataga aattactgcc atgtttgttt cctccgattt ggttttattt
     3301 ttcctcttct tatcttctac cttgccggca aactttttca agcacctacc gacaatccaa
     3361 taagaatgtg gatttgctga tgcataaagc accctcagct attatacaga caaaagatcc
     3421 gtatcgcaag agcaaatata cttttctgct caacattcaa tagtttacct gaaagataaa
     3481 aagaattcaa gaaaaacagt agatttctct ttgtttcttt attatccttt ttccataaaa
     3541 taattttagg tataaaagac gaatattatt gggcaatcct tctttttttt gttatgatac
     3601 atgtgaaatc tttcgtaaag gagaaagaaa atgcgcaaag ctcaaagaca tttgctgatt
     3661 aaacaagtca ttgaagaatt cccgatccgt acgcaagaag aactattaaa caaacttggg
     3721 cattatggcg ttaccgccac gcaggcaacg atttctcgag atatccgtga tctaaaaatc
     3781 gtgaaggcac ctgatgaaaa tggcgtttcc cgcttcgtat tgtttcgcga aaaaggaact
     3841 cctgagacta ggactgagga agaggatcgg ctggttcaaa tgattgaaga cattgtattg
     3901 aaagtcgaac gagtccactt tttgacgatc gtcaatacct tgccagacaa tgctcattta
     3961 tttgcatctg ttttagatga gatcaaacct ccctctattg tcagtacaat tgctggattc
     4021 gatacgatca tggtcatctc ggaaaatgag gaggacgcaa aacgagtaga agaatttctt
     4081 caccatccaa ctgaagtatc acttttttaa tcagagcacg tattcctaat atggaatgcg
     4141 tgttttttta ttttcaatat tttccttatt gaataaacct ttacactctt tacaaaaata
     4201 catcattttt tattcaaatt tttcaacacc ttgattgaat cacaataatc atcatttata
     4261 ttggatgtta acaagagcag cttcttgctc tttgtgtatt tcaaaaaaga aatgaaagga
     4321 aatcatatgt ataaattatt aacttctgga ccattgacga cttctgaaac agtgaaaaat
     4381 gctatgctga tcgatcattg tacttgggat caagaataca aagaaattac acaatggata
     4441 agaaaaaaat tattggatct tgctcaagta tcggaaggaa tatacacaac ggtcttaatg
     4501 caaggtagca gctccttcgg ggtagaatcg gtattaagtt ctgtgatcag gccagaagat
     4561 actgtactga tttgttcaaa cggcgcatat agacaacgaa tgatcaacat gtgcgaatgt
     4621 ctgaaactga actataccgt ttatgaggta tcggaacatc aaatcctcca agctcatgtg
     4681 attacacagc tgattgaaga gaatccgtct atctccgcac tagcaatggt ccatagcgag
     4741 actacttccg gtattttgaa taatttggaa gagattgctg ctgtcacaca agaaagagat
     4801 cttttgttta tagtggacgc gatgtcaagc tttggtggga taccgatttg tgtagccgaa
     4861 ctagggattg attttttgat ttccagctca aacaaatgta ttcaaggtgt tccaggcttt
     4921 tcttttgtac ttgctaataa agcggaactg gaaaaacgaa aaaatgttag ccgaagtttg
     4981 tcacttgatc tatatgacca gtaccgcgtg atggaaaacg agaatggcaa atggcgtttc
     5041 acttccccta cccatacggt tttggctttt caacaagcgc tgaaggaact agaggcagaa
     5101 ggaggaatcg aaactcgata ttcacgttat ctcgccaata atcatgtgct acgacaaaaa
     5161 atgacagaga tggggttcca gcctttcatt caagaatatc aggggccatt catcacctct
     5221 tttctttacc ctaaggactg gcgatttgat tttaatcatt tttatcagta tttaaagcaa
     5281 aatggatttg tgatctatcc cgggaaaatc agcgatcatg aatgttttcg tatcggaaat
     5341 attggcgaga tctatccgga agatattttg gaactgacag caattatcaa agactataag
     5401 gagaacgtta atgattaaaa ctgtaatttt tgattgggca ggaacaactg tggactttgg
     5461 ctgtatggct cctgtccacg cttttagaaa tgcttttcta gaaaaaggaa cccaactgac
     5521 tgacaaagaa atccgctaac cgatgggaaa attaaaatgg gatcatatcc aacagcttct
     5581 ttccctccct tctgtcaaaa aacaatggat agctatttat ggacaactac ctcaggaaaa
     5641 agaggtggag gaattgtatc aacaatttga acattatctg tttaaagatt tggtcaagca
     5701 ttctaccttg aaacccgaca cattggaaac gatcgaacgg ttgagaaacg ctgggatcaa
     5761 tattggttcc acgaatggat ttaatgctcc tatgatgaca atcgtagcag aaaccgcaaa
     5821 aaaagaaagg tattcaccag acttcatggc aacttttgaa gacgtcgaag ggtatggtcg
     5881 accgtttcct tatatgatcc ataaaaacat gcagtacttc aaaaacaagt cggttgatga
     5941 agtaatcaaa gtcggagata cggtctcaga tatccaggaa gggaaaaatg ccggagtgtt
     6001 gacagtaggt gtaattgaag gtagttcgct aatggggatt tcttatgatg agtaccaaaa
     6061 attagagatg gggaaaaaga tcgtttaaaa cagtctgttg ctcttagatt ccaacaagcc
     6121 ggcgctgata tttgtgtaaa caatttaaaa gagttaacag aatacatttt gtacgctgac
     6181 aagaatccag aatgactttt atacaaaata agaggttgtg aaaaagctgt cctgtatcaa
     6241 gtaataaaaa cagccaagca aaaatagctc ctcatatttt tcgtttggtt aggcttatta
     6301 ccgcagatgc aagcttttga acaccgttta ttcgaaaaaa aaaagggagc tgtgacacga
     6361 cttttgtcac agtcccctta tttgcaaaca aacagtgttt aagagacaac ctctccacta
     6421 aacggtgttc attcagctga ctctcggtat ttgctcaaaa aacgataaaa tttgaaaagc
     6481 tattttctct tttgtttctc taatactcgg atcagaacgc tgatttcaca ttctcttttt
     6541 cttacatctt atctggtgca tgaagtccta gcaaacgaag gtcttctttc aataatacag
     6601 tcactgcata aactagagct aagcgtgctt ctttttgttc atcatcagct aaaatcttcg
     6661 tatgagcata gtatttgttg aatgcttgtg ctaatttgat tgcatgtttc gcaatcactg
     6721 acggttcgta tttttcccca gcagacaaga ccgtttcagg gtatttttga actaatttaa
     6781 ccacttccca gctggtatcg tcattcaatg catagtctgc tgtttctgaa gggacaaatc
     6841 ctgctttttc caacaggctg actgcacgag catgtgtata ttgcacataa ggtccagttt
     6901 ctccttcaaa tcgaacaact tcttccaggt taaagtcaaa tgtattcagt cgatcgtttt
     6961 tcaaatcgtg gaaaatgact gccccaaccc caacttgttt agctacagca tctttgtttt
     7021 ccaaatcagg gtttttctcg ctgatttgtt ctttagcaga ttggattgct tcatttaata
     7081 cttcttctaa taagacgatc tttcctttac gagttgataa ttttttacca ccttgcgtga
     7141 tcaaaccaaa tggaatatgg tgcatgtcgt cagaccagtc aaagcccatt tccttcaaga
     7201 cagctttcaa ctgtttaaaa tgatagcttt gttcattccc tactacatat agagattgtt
     7261 tgaagtcgta agtacgttta cggtacaatg cagcagctaa gtcacgtgta atgtatagtg
     7321 tcgcaccgtc tgacttctta atcaacgctg gattcaggtc ataagcagat aggtcaacga
     7381 tctctgcacc tttatcctcg ttcagcaaat gtttttcttc taaaagtttg acgatttcat
     7441 ccatcttgtc attgtagaaa gcttcaccgt tcaacgaatc gaaacgtact tccagcagat
     7501 catagatttt attgaattct ttcatcgatt catcacggaa ccattgccat aattgaatag
     7561 cctctttatc gccttcttcc agacgtttga accaagcacg agcttcttca tttaattctg
     7621 gttctgtttc agctacttca tggaattgga cgtataaacg aagcaattca ttgattggtt
     7681 ctgctttaac agcttcttct gtaccccatt ttttgtaagc gacgatcagt tttccaaact
     7741 gtgttcccca gtcacctaaa tggttgatgc ggattggctg ataaccgatt ttttccataa
     7801 tgaaaccgat cgaattaccg ataactgtcg aacgcaaatg tcccattgag attggtttgg
     7861 caatattagg agaagacatg tcgattggta ctgttccttg attcccgatg ttgctatccc
     7921 cataatgttc tttttctttc actactgttt gcaaaacttt tttgctgata agttctttat
     7981 tcatgaaaaa gttcaagtaa ggtccgacaa cttcgatttt ttcaaagttg gcagaatcga
     8041 ttttttctgc taaatctgca gcgatttgct gtggcgcttt tcggtaaact tttgctaatg
     8101 aaaaggctgg aaatgcaaca tctccgtgtt cagctgattt tggattttct agtaattgct
     8161 cgacttgttc cagtgttaaa tcatctttga cagcgtcata gacagctttt gcgacaagat
     8221 ctttattatt catctttatt cctcctaaag tgttcccttg attgttaaac aaaaaaaatc
     8281 tctagcgacg gcatacttag tatgccatca ctagagacga gatttcccgc ggtaccactc
     8341 caattgtcct aaaaaaggac cagctccatc tgatatcggt agacgaccgt ctgtttaaaa
     8401 cagaattctc caagtgcgct tcgttgtatc ttcttcattc ggcttccacc acttccgaat
     8461 tcgctagcca agaatgatac aagtactctc ttgttcaaca aatcttagtc ttattaaact
     8521 ttcttgaatt atatcagaaa aaaaaacgaa aggctagtcg tttcataaaa aaaaaatcca
     8581 gatggcctaa aggagaagaa ataccacctg gatagctata aatcatttcg taaatacgaa
     8641 agacttaaca aattaatcag ctacgataat cgttccttct tcagaagcta aaagattctc
     8701 gatattttct aaagaagtga tgattgcctt agcgtttggt tttgcttcaa caaatgcaat
     8761 agctgcttct actttcggaa gcatgcttcc tggagcgaat tgcttttcat caatgtattg
     8821 tttcatttct gaaacagtaa cagtttctaa tttcttttga tctggttttt ggtaattgac
     8881 atacacattg tctactcctg tcaatacgat cagcaaatcc gcatcgatga tttcggctaa
     8941 tttttctgaa gcaaaatctt tatcgattac ggcttctcgt ccttctaatc cagtagctgt
     9001 ttctacaaca ggaatcccac cgccaccaac agagactgtg ataactcctt gatcgaccag
     9061 cgtttcgatg acacgtgctt ctttaatcga gatgggttta ggggaagcga ctacttttct
     9121 ccatccacgt ccagcatctt ctttgaatgt cacagtggag tcagcattca tttgttcttt
     9181 ggcttcttct tccgtgtaga atggaccgac tggtttactt ggatttttga atgaaggatc
     9241 attttcatcc acaataactt gagtgactaa agaaaccaca tctttatcga tccctttttc
     9301 cttcagtact tcgcccatgg cgttttgtaa ccagtaaccg atagatcctt ctgtcattgc
     9361 aacacatgta tctaaaggca ttgccggtgt tttctcagaa tcagcagctt gctgctgaat
     9421 caataggtta ccgacttgcg gaccatttcc gtgggagatg atcaattcat ctccttgttc
     9481 gataaatttc actaaatact ttgctgtttc cattaacgct tcttgttggg cttttgcact
     9541 tgcatccgta gacaagatgg cattgccccc taaagcgaca actacttttc gtttggccat
     9601 ttcattcgtc ctttcttcag ttctaccgaa ttttctagat aacaaaacga gccagcgttt
     9661 tgtgattttc cctcaatgct gactcgtttt ttcgtgagat gaatgtggtt atgcttaaac
     9721 gcgagggata aacaagttac ctaatgttgc tgccatgatc gctttgattg agtgcatacg
     9781 attttctgct tggtcaaatt gacgagcata tttgctgcgg aagacttcat ctgttacttc
     9841 catttcagtg atgccaaagc gttctttcat ttgttcaccg taaacagtgt ttgtatcatg
     9901 gaaagctggc aagcagtgca agaagatcaa acgatctgtg ttgtgtgttt tttctaccat
     9961 ttccatattg atttggtaag gtttcaacaa tttgatacgt tcttcgaatt tatcttcttc
    10021 acccattgat acccatacat cagaataaag gacgtctgct ccgtctacac ctttatcaac
    10081 atcgtcggta atcatcaatt gtgcaccgga tttttcagca aagccttctg ccattttgac
    10141 gatttcttct tcaggttgta attcttttgg tgcaacgata cgcatattcg ctcctaaaat
    10201 tgcacctgtg actaataaag agttagccat attgtttcga ccatctccgc agtaagcaac
    10261 agtgatacct tctactgttc caaagttttc ttggatagtt aaaaagtcag cgatcatttg
    10321 tgttggatgc cattcatcag tcaagccatt ccaaactgga acaccagaga attctgctag
    10381 ttcctctacc attttttgac tgaatccacg gaattcgatt ccgtcaaaca tacgtcctag
    10441 tactttagct gtatcttctg tggattcttt tttacctaat tggatatcat ttgcacctag
    10501 atattcagga tgtgcaccta gatcgatcgc tgcagtagta aatgcagaac gagtacgtgt
    10561 agatgttttt tcaaataaaa gcgcaatatt ttttccttct agatagtgat gtgggatacc
    10621 acgttttttc aagtctttca agtgttctga aaaatcgatc aaatattgta attcttcttt
    10681 tgtaaagtct ttttctgcta ataagcttct tccttggaat actgattctt tcatattaaa
    10741 cattctcctt tagattgttt ttatttaaga ttaaagagga aatcccgacg gcagctgaca
    10801 gtaagactgc cgtcaggaaa caaattactt caagtcttca cggacaagtg gttggctcat
    10861 gcagcgtgga ccaccacgac ctcgtgacaa ttcacttgaa ttgatttcta acactttgat
    10921 gccatagcta cgaagcaatt cgttcgatac ataatttcgg ttataagtga ctacaacacc
    10981 tggagcgatt gccaatgtgt ttgatccatc attccattgt tctcgaggtg caacgatctc
    11041 atctccatta ccagttggga tcagtacaag atcatctaat ccaagagcag ctttcatcgt
    11101 ttcgtgtaag ttatctgaat gagtaatctt gatatcatca ccatctggtt cgattgtaaa
    11161 gacatccatc ttaccgtctt tactttgaat tgctggatgg atagtgaatt tatcgtgatc
    11221 taccattgta aatacggtat ccaaatgcat cattgcacgg ttgttcggaa ttttgattgc
    11281 caacactttt tcaaatcctg aattttttgc gaataggtgg cgtgctaatt tttctaaagc
    11341 tttcgcatta gttcgttgag aaatcccaac agctactact ttatcgctta agatcaattc
    11401 gtctccgcct tcgatatgat ctggattttc acgatccaac catacttcga ttcctttatt
    11461 tgcaaatctt ggatgatgtt tcaaaatata ttctgtaaac atcgattcac gacgacgtgc
    11521 ttcaaaagtc atcttattga ctgtcatccc atttcccatt gatgcggaag ggtcgcgtgt
    11581 aaagtacaag tttggcattg ggtccatgta aaatggatag tcatcgtctg ctgacagatc
    11641 atatagactg ctagaacgta cttcgatatc ttttgtacga accccagcca tgattttatc
    11701 taccatttct tgcgtttcca ttgatagaag gaactcatga agaccctctc ttacagcatt
    11761 cgatgcaata tgagattcat ccaacatttt attcaagaat tgttctttga cattgcctgc
    11821 gtcaatcgct tctgccgcta atttttccaa gtaaagagtc tcgacgcctt cattttgcaa
    11881 tgtcttcgca aagttgtcat gttcttcttg agcaatcgga agatatggaa tatcatcgaa
    11941 caacagacga tccataatat ctggtgtcaa attttccact tcttgtccag gccgtttcag
    12001 taaaactgtc tttaatttcc ctatttcaga gaaaacgtga ataggtttat ccatgttgtg
    12061 ttgcctcctt ctttttgatt acatgtatag gatatcctcc ttttgtaatc actttcataa
    12121 ttttgtctca ttcaaaatga gacattcctc acattaatat tcgataatta aataattaaa
    12181 cgtttttcta tttttaagcg taatttattc attttttatt ctgtatacac tttcaaaaaa
    12241 atatttattc attgaaaaaa tttttttgaa t
//
LOCUS       DADLIO010000079        12252 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.082, whole genome shotgun sequence.
ACCESSION   DADLIO010000079 DADLIO010000000
VERSION     DADLIO010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12252
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.082"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            64..1122
                     /locus_tag="JOX41_002365"
     CDS             64..1122
                     /locus_tag="JOX41_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HAY6450074.1"
                     /translation="MVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPGLLARQGF
                     IEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQIFYITLSS
                     SRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFSFGTNYAK
                     DFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIWKAALKVI
                     RPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLVSSGIIAF
                     ICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFNKRDVISI
                     VFWYYLGSISYLYLKKEN"
     gene            1124..2194
                     /locus_tag="JOX41_002366"
     CDS             1124..2194
                     /locus_tag="JOX41_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450075.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKKIDDYF
                     VYCPELLLYDVKNIKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYG
                     IDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTL
                     LISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLS
                     EEKILLPENWAELRKLVEYGII"
     gene            2181..3602
                     /locus_tag="JOX41_002367"
     CDS             2181..3602
                     /locus_tag="JOX41_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HAY6450076.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFSLILHILINQMLIRYVLTS
                     LLIISLVIYFLKIKNRIIDDYNS"
     gene            3615..4622
                     /locus_tag="JOX41_002368"
     CDS             3615..4622
                     /locus_tag="JOX41_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAY6450077.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            4634..5638
                     /gene="neuB"
                     /locus_tag="JOX41_002369"
     CDS             4634..5638
                     /gene="neuB"
                     /locus_tag="JOX41_002369"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HAY6450078.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            5635..6783
                     /gene="neuC"
                     /locus_tag="JOX41_002370"
     CDS             5635..6783
                     /gene="neuC"
                     /locus_tag="JOX41_002370"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HAY6450079.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            6756..7433
                     /locus_tag="JOX41_002371"
     CDS             6756..7433
                     /locus_tag="JOX41_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAY6450080.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            7423..8565
                     /locus_tag="JOX41_002372"
     CDS             7423..8565
                     /locus_tag="JOX41_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HAY6450081.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            8578..9555
                     /locus_tag="JOX41_002373"
     CDS             8578..9555
                     /locus_tag="JOX41_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAY6450082.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            9555..10463
                     /locus_tag="JOX41_002374"
     CDS             9555..10463
                     /locus_tag="JOX41_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HAY6450083.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            10464..11216
                     /locus_tag="JOX41_002375"
     CDS             10464..11216
                     /locus_tag="JOX41_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HAY6450084.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            11221..12168
                     /locus_tag="JOX41_002376"
     CDS             11221..12168
                     /locus_tag="JOX41_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HAY6450085.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT         4396 a         1537 c         2223 g         4096 t
ORIGIN      
        1 attactttga tagtaatttt tcctgcagac ttttcacaaa gtgaagagga aaaaaagaaa
       61 aaaatggtgt attttaataa tgttttcatt atcataattt ttttagctgc gctaatatct
      121 atctatcaat ttattttttt gatttcttat catgtcccaa caggaacgcc aggattactt
      181 gcaagacaag gttttattga acatcggtta tttggtgtct atacaagtcc aaatgttgga
      241 gctatgtttg gatatacttc tattatttta agtttaatta gtgtattaat ttcaaaaata
      301 acaaaaacga ttcgtgtttt ttatatgatg aattttatcg tacaaatatt ttatattaca
      361 ctttcttcgt ctagaggtgc ccaggtagta atttgttctt ttttagtatt atttcttttg
      421 ttgtttgcca attcaaaatt tagaaagagc attagagaag tactacctgt aaaaatcaaa
      481 tggatggtaa gcatattatt agttctattg gtatattttt cttttggtac taattatgct
      541 aaggattttt tagcaacaat tcctgtatcg attgatagaa aagtagaagt tatagagtca
      601 aatgaatcag ataaaactcc acttccagaa aaagaagtaa tattacagca ttctagtgat
      661 aactccgaaa tttcagctgg tcgttttacg atttggaaag ctgcgcttaa agttataaga
      721 ccaactttgt tatttggtta tggagagacc gatttctatg ggaatagcga tgcaaaattt
      781 ttgaaaaaag tagatcttga tactacagat gtgaatgaac taaaaagagc acatggaaac
      841 atgcataatg gatttcttca agtacttgta tcaagtggta taattgcttt tatatgtatc
      901 tatgctttct atgtgttaaa tatctttagt ttactcaaaa cattttttag aagtaaagtg
      961 aattatgcgt ttcttggtat tgttttaatt tttatactat ctatttttat agatgaaatg
     1021 gtggaggctc atgtactttt caataagcgc gatgtcattt caattgtttt ctggtattat
     1081 ttgggaagca tttcttactt gtatttaaaa aaggagaatt aatatgaaga cagctttcat
     1141 tgcttggact cctttacatt tgattaatat attaaatgtt tatcaaaatt tttaccgaga
     1201 atcaaaagga gatttattta tttattctga atttgaaaac gctagaagat atagtgagcg
     1261 tataaaagaa ttagggctat ttaatgatgt tgtttttgtg aatcaccgga aaatcggttc
     1321 ttcctttaaa cgtaaaatta acttgttaac taaccataat caatttttct cggatgattt
     1381 atccgtttat gatgaaattt ttatacaggg ggaaaattat ttcacaaaaa tacttttctc
     1441 caatgtttac aaaaaaaatc cagatgtaaa actaaattat atagaagatg gtttgggtac
     1501 ttatttgaag aagagtatat tttcaacaag taaaaacgtt caaagagttt ttaaaatatt
     1561 aaataaaaat agcatcttca aaaaaaaaat tgacgattat tttgtctatt gtccggaatt
     1621 gttactttat gatgtaaaaa atataaaaaa aattcccaaa atagatgaaa acagtaaatt
     1681 gatgaaaaac atacaatcaa tctttgggat agaagaagtt tttgtcggag ataaatgtat
     1741 cttttttgat caacctttat tatctgatgg ttatggcata gatgaaacag atattttcgc
     1801 taaagtaaat agtatatttt ctggaaaaaa agaaacttta attaagcttc atcctagagc
     1861 aaggacaaat cgttatggtg aaaaaaacat attgaattcc agtttaccgt ttgaagtctt
     1921 gctacttgaa aatgacttct cttcaacact tttgattagt cctatatcta caatttcttt
     1981 ttcaccatct atgatgtttg aaaagacgat caactctatt atgttggcta aattaatttt
     2041 aaatgaatat acagcattat ctgaagataa aaaagaaaca ttgacaaata ttgttctttt
     2101 ctgtgaacat tataaccgtc tatcagaaga aaaaatttta ctcccagaaa actgggcaga
     2161 attaagaaag ttggtagagt atgggattat ttaacacact ttccaagtca aaattagtta
     2221 agtccagttt ctggtatact atagggaatt tttttattaa gggaatttca ttcataacta
     2281 ttcctatttt tgtaaatatt actactcaag cagaatatgg tttgattaat aatttcactt
     2341 catttgtatc aattttttcg attcttgttg ggctaagcct aaattcggca attaataatg
     2401 caagttttga ctataaagat gacataaatg aatttatgtc atcggtactt tctctagcta
     2461 cactttcgtt aattgtgttc ttattaatag ggaacatata ttttttgttt tcaaatgctt
     2521 tttttgatat gaaccaactt gtatttaatt tgatgttatt acaaagtttt gctagttttg
     2581 taattagtta tatccagtct tattttacga ttaactttaa ccattttaaa tatttgattt
     2641 tatcttttat atctactttt ttgaatattg caatctctgt agctttgatg cagacattat
     2701 attttgatga taaatatgtt ggcagagtag tcggcggaac actgtcattt gtgttgatag
     2761 gtttagtaat ttatttaaga ataatgataa agggtgctca tttttttgat aaaaaacagt
     2821 ggagatacgc tttaaaaatc tctttgccgc taatcccaca ttccttagca aatatagttt
     2881 tagcacaatt cgatagaatt atgattaatt cttatttagg tcctgctgcg gggggaatat
     2941 attcctacat tagtaacata ggtattattc taagcgtaat atggatgtct actaataacg
     3001 cctgggttcc atggttctat ggtgagatga gtaaaaataa tgaaaaaaaa gtgaagaaag
     3061 ttagtaacta ttatttagta gtctttactt tgattacgat gattgtaatg gtagtttcga
     3121 ttgatttagc aaaatttatg gctccgaaag actattattc tgggttatct ttagtggttc
     3181 cgataacctt aggctatttc tttcagtttt tatatagttt accagttaat gctgaatttt
     3241 atgagaaaaa aacatcgttt attgcgattg gtacagtagc aagtgctata gttaatatac
     3301 tattaaacat gattttcata cctaggttag gaataattgc tgctggatac acaaccgtat
     3361 ttacgtattt tttacttttt atttttcatt ataatatcgc taaaaaaatt acgaataaac
     3421 aattatttga cacaaaaaaa atatgtatca taataatttt tgtatcaatt ttttctttga
     3481 tacttcatat tttaatcaat caaatgttga ttcgttacgt tttgacatca ttattgataa
     3541 ttagtttagt tatatatttt ttaaagatta agaatcgaat tatagatgac tataattcat
     3601 aggaggagat ataagtgttt aaaggaaaaa caatattagt aactggcgga actggttcca
     3661 ttggaagtga aattgttcgt cagcttttaa aatatgaacc aaaagctatc agaatttata
     3721 gtagaggtga agaaaaacaa ttttatatgc aacaagagct ctcaaatcac actaatttga
     3781 gatttttaat tggtgatatc agagactctc aaaggattga ttatgcatgt cgtgatgtgg
     3841 atattatttt tcatgctgcc gcaatgaaac acgttccagc aagtgaatat aatcctatgg
     3901 aagctgtaaa aacaaatgtg atgggaactc aaaatgtaat agatgcagcg atcaaaaata
     3961 atgtaaaaca ttttgtaggt atcagtacag ataaagtagt gagtcctact aacaccatgg
     4021 gtgcgacaaa gttattgagt gaaaaattaa taatagctgc caatcagtat aaaggaaaaa
     4081 cagaaacaat attttcttgt gtaaggtttg gaaatgtcat ggggtcaagt ggatctgtta
     4141 ttcctctttt tagtaaacaa ataaaaaaca ataaagatat tactttgaca gatgttgata
     4201 tgacacgatt tatgatgtca ataccggatg ctgcaagatt agttctgtct gctgctatga
     4261 attcaaaatt tggagaaaca tatgtcttaa aaatgccggc aatcaatatt ttaactttag
     4321 ctcaatcatt aataaaaata tataatgata cacatgatga aaaatataga ggtgaaataa
     4381 aagttgtagg tatcaggcca ggagaaaaat tatatgaaga gctaatgact acagacgaaa
     4441 ttgaacgctc atatgaaaat gataaaatgt atatcattcc accacactat catgctactg
     4501 acgaactgta caaagattat gaaaaaatta aaatcactgc atactcttca gatgcaacag
     4561 aattaatgag tggacaggaa tttattagaa tcgcaaaaga gaataatgtc gtgacttggt
     4621 aaggagtttt atgatgaaat cagaagtata tgtaattgca gaaattggtg taaaccataa
     4681 tggaagtcta gatttagctt tagaaagtat tgataaagct aaagaatgtg gagctaacgc
     4741 ggttaaattt caaacattta aaacgaataa gctagtttcc aaaaaggctc caatggcaaa
     4801 atatcagaag gataatctta aagaggacag ttctcaattt gaaatgctaa aaaaattaga
     4861 attatctcaa tctgatttta ttagaataaa agattattgt atacaaaata aaattgattt
     4921 tttgtctact ccttttgatg aagaaagtgc agactttcta aaacaaattg gtgtacaagg
     4981 atttaaaatt ggctcaggag atttaacaaa tttacctttt cttagaaaaa tagatatgta
     5041 tgggttgcca gttttattat ctacaggtat ggctgatatt catgaggtca gtgaggctgt
     5101 agattgtttc atagatagtc cagttactat tttacattgt acttcaaatt atccggctag
     5161 ttctgaagat attaatttat tggcgattaa cacattaaaa gaaatgttcg ggatacccgt
     5221 tgggtactcc gatcattcat tgggatatga tgttggtatt tgtgctgttg cgatgggtgc
     5281 taaggtaatt gagaaacatt ttaccttgga taaggaacta cctggtccag atcataaagc
     5341 ttctttagat cctcaggaat ttgcagattt tgtaaagcat attagaaaca ctgaaatatt
     5401 tttaggtgat ggtgttaagc gagcaatgcc ttctgaactt agtacaaaag aagtatcaag
     5461 aaaaagccta gtggtcactg agaatttaaa tgtgggagat attcttacag agaaatctct
     5521 tacaataaaa cgtcctggaa atggaatagc tcctaagttt ttatatcaat atattggcaa
     5581 aaaagttaaa agaccaataa gtgcagatag tgttctgctt gaggaagatg ttgaatgaaa
     5641 aaaatactta tagtaagtgg aacacgagct gattatggaa tatataaacc tgttgctgag
     5701 aatttactac aagataattg ggatgtatca tttgttgttt ctggaatgca tttatcccat
     5761 aaatatggat ttactaaaga attgatctta gctgacggat ttagaattag tggagaagtt
     5821 caaagtttgt ttttagagaa caataaggga aacatggctc ggtctgtggc attagagata
     5881 aatggtttca caaatatatt tgaacaaact agccctgatt ttgtattatt actaggggat
     5941 agaggagaaa tgttggcagc tgcgatagct tgtttgtatc ttggaatcaa aacagcacat
     6001 attcacggag gcgaagtgtc tggtactgta gatgaatcaa taagacatgc cataacgaaa
     6061 atagcatctg ttcattttgc tgctacggaa aaaagcaaag agcgtttaat aaaaatgggg
     6121 gaagattctt ggagagtttt tcccgtcgga gctcctagaa tagatactat tttaaataat
     6181 agattaccta gttttagaga tataaaagaa aaatatcatc taaaatttga aaagaaaaaa
     6241 tacgttttgc aagtatttca tccagttgta accgaactag aaaatataga aaaacaaatt
     6301 ttagctttga tcaattcaat ggaacaacaa tctcaaccaa ttatttgcat tttacctaat
     6361 agtgatgctg gtagcgaaat tatcagaaaa atgtaccaga aatatttaaa aacggatatt
     6421 atttatatta cgaatttaga gccggaggaa tacctgacta tattaaaaga gtgcaaattt
     6481 atgatcggaa attcttcttc tgggataatt gaagctgcat cattcaaaat accagtaata
     6541 aatttaggaa ccagacaaaa tggacgagaa caatctaaaa atattataaa tgcaaatcta
     6601 aatgaaaatg aaattgaaac tgctttgaat aaaatacaag atcctcagtt tataaaaagc
     6661 ttgaaaaatg ttaagaacat ctacggtgac ggcaacagtt ctagaagaat aacaaaaaca
     6721 ttgaatcaaa tattgaatga tggggaagat attaagtgga ttcaaaaaca aatagcttat
     6781 taaaatatac tagtgatcca tacattatta ttggggctgg cggacacgca aaagtcatta
     6841 ttgaaacctt aagattagaa aataagttaa tatatggatt ttttgatgat aagcaaaata
     6901 aaatgcaaga tctgaaatat cttgggaaaa taaacgaatt gaatagctgg gcggatagca
     6961 aaaaaaaaat ctataaattt attgtagcta ttggtgactg tgtagtaaga aaaaagatta
     7021 taaaaaaatt gaatatgcca agtgagcaat atggaatagc tgttcatcca agtgctatag
     7081 tggcaaaaga aatttcaatt ggttatggaa ctgttatttt tgcgaatgct gtaattaacc
     7141 cagatgctgt aattggagag catgctataa taaacacagg tagcattgtt gagcatgatt
     7201 gtagaattaa taactatgtt catttatctc caggtgtatg cttagcgggt ggagtacatg
     7261 taggtgtagg aactcaaata ggaattggtt ctcaatgtat ccagatgaag aaaattggat
     7321 cttggtgtat gataggcgca gggagcacta ttgttaagga tattccctca cattccttag
     7381 cttatggcaa tccagctaaa attaagaaag aaggaattaa ttttgaattc tagaatttta
     7441 ttatcaagtc ctcatatggg aggaacagaa gaaaaatatg ttgctaaggc ttttaaagat
     7501 aattggatag cgccattagg tgaaaatgtg gataaatttg aagaaagtat tacaaaatat
     7561 actggttcta agggcggagc ttctgcgtta agttcaggta cagctgccat acatcttgcc
     7621 ttaagactgc ttaatgttgg aaaaaacgat attgtctttg ctccttcatt tacttttata
     7681 gctacagtaa atcctatttt atatcaaggg gctgtaccag tgttcattga ctcagaacct
     7741 aatacatgga atatgagccc tgttgcacta gagagcgcat tagaagaagc tgaaagaaac
     7801 aaccaattac ctaaggcaat catcgtagtg aatttatatg gtcaaatggc tgattatgaa
     7861 cgaattttag ctattgcaaa ccaatttaat gttccagtga tagaagatgc agcggaatcg
     7921 ttaggttcta cttataaggg aatttcgtca ggcttatttg ggacaattgg gatctattca
     7981 tttaacggta ataagatcat cacaacctca ggtggaggag ctctagtgtc tagtgataaa
     8041 aaatatgttg agcattcaag atttttagca acacaagcaa gagatcaagc accgtattat
     8101 caacatagcg aaataggtta taattaccgt ctaagcaata tttctgccgg tatcggacgt
     8161 ggacaaatgg aagtattgaa tgatagagta gctaaacgaa gagaaatttt caatcgatat
     8221 aaggaagctt tttctggaat tgatagaatt gaaatgatgc cagaagtgga tggcatggtg
     8281 ccaaatcgtt ggttgtctac tttaacgatc aatgattata attctattga tcaagtagtt
     8341 aacgtaataa ataaactaaa tgaaaaaaac attgaaacaa gagctttgtg gaaaccacta
     8401 catttgcaac cagtatttca aggggtaaaa atgtattacc atgataataa tcttagtgtg
     8461 tcagaaaagt tatttaatag cggcttatgc ttaccttctg gaagtaatat gacagatagt
     8521 gaacaagaat ttgttattga tgagtttaaa aaaatattca agtaggtgtg atattttatg
     8581 aacataggaa ttattggttt aggttccatg gggaaaagaa gacttagact cattcaagaa
     8641 cactttaatg atattttact atgtggtgtt gatactaatg aggcgagacg aaaggaagtt
     8701 gaaaaggaat ttggaatacc aacttataat agtctaacag aggcaaaaaa tttgtttgaa
     8761 ataaattcag tttttgtttg tacatcccct ataacccatg aatttattat aaaagaggct
     8821 ttaaatttag attgtaatat ctttacggaa atcaatttat taaatgaata ttatgatgaa
     8881 ataatcgaag tagctaaaaa gaaagataga ttactttatc tatcttctac atttttgaag
     8941 agaaaagaaa ttcaatatat taagtctaaa gtgacgcata ataaaaaaat ttcttatcaa
     9001 taccatgtag gacagtattt acccgactgg catccttggg aagattatcg caattttttt
     9061 gtttcaaaca aaaaaactaa tgggtgtaga gaaatattcg ctattgaatt accttggatt
     9121 atagatacat ttgggaaagt taaatcgttt actgtaatga cccagaaatt atccaatctt
     9181 gatattgatt attcggacag tttcactctt attattgagc atgaaactgg tatagttgga
     9241 actttaagtg tagatgttgt ttcaagagta gctaaaagaa atttaactat aattggtgaa
     9301 aagattttaa tagaatggga aggtaacccg gattctctat tttcatggaa tgaagaaact
     9361 tctagtatga cagatattca attgtacgat gaggttatgc atgataataa ttattcacat
     9421 actattattg aagatgcata tttagaggag attaaagaat ttttcacgct tttggaaaag
     9481 aaaatggaac cccaatatac ttttgaaaaa gataagtata ttattaactt aattaacgac
     9541 attgaggtaa attaatgatg aaagtaattt tttttgggtt agggtcaatt ggaaagagac
     9601 atctaaaaaa tctaataagc tatggaaaaa agaattctat taattttgat ataacagctt
     9661 atagtagcag tggaaaaaaa gagtttgaag aaataacgta tattcaaaat agagacgatt
     9721 tggatacaca ttatgatata gcttttatta caaatccgac ttttaagcat ctggaaacac
     9781 taaatgtaat tgttgaaaaa gttgattaca tatttttaga aaaacctgct ttttctgaga
     9841 gtattgatct tactcaatat aattatgatt acaaaaatat ttatgttgct gctccactga
     9901 ggtataaaaa tatcatggaa gttgttcgta atagtattca aagtaaaaaa gtatattctg
     9961 taagagctat ttgttctact tatcttcctg attggagaaa aggtactgat tatagaaata
    10021 attattctgc ctttaaatct atggggggag gagtagaatt agactgtata catgaattgg
    10081 attatattat aaacctattt ggtttcccta aatcagtaaa aaaacagttt ggtaaatatt
    10141 cgaatcttga aattaacagt aatgatttag caacatatat attgagatac gatgataaaa
    10201 ttatagaaat tcatttagat tattttggaa gagttcctac aagaaaattt caattgttta
    10261 ctttagatga atgtatcaat gttgacttat taaataataa aataagtttt gaagaaaaca
    10321 ttgttaaaga aatgcctgaa tctgctaatg atatgtatga gaaggagttg aaatatttct
    10381 ttgaaaacgt agtaacaggc aaagaaaact ggaatgattt atatcatgca aacgaagtat
    10441 tgaaaatagc tgaggagaaa taaatggaaa ttttatttac tatttgtggt agagctgggt
    10501 ctaaggggtt taaaaataaa aatttgaaat atttggcagg aaagccccta gtccatttcg
    10561 ctttagcaat gatagatatc tatcaacaaa aacatcctga acataattgc acgacttgtt
    10621 tgaatacgga cagtaatgag ttagtagaat tgacgactaa gttaaatccg tctgtgaaaa
    10681 ttgtagaacg taaacctgaa ttagctacag atactgtagg gaaaattgaa gtgatacgtg
    10741 attcattctt acaactagaa agagaagata atatatttga tttaattata gatttagatt
    10801 tgacttcacc tttacgtgaa gtttctaatc ttgaagaatt aatagatgaa catctaaaaa
    10861 atttagataa agacgtctac ttttcagttg tttctgcaag acgtaatccc tattttaata
    10921 tggtaaaaag aattgaaaat gaagttacta tagttaataa atcaagatac acatctaggc
    10981 aacagacacc tgaagttttt gaaatgaatg cctcaatgta ttcttttaaa cctgaatttc
    11041 taaaaaaaag taattatatt tttgatgggc aatgtgggat aataaaaatg agagattatc
    11101 taattttaga tattgatagt gaagaagatt ttaaatggtt agaatttttg tttcctaaat
    11161 ttttagaaga ttcttcggag cttcaagata tctataatta tttatatcgg aggtaaaagg
    11221 atgagctgtt atcttatcac cggtggggct ggcttcattg gttctacctt agccaatcat
    11281 ttaggagaag aacatgtggt aatcgtcgtc gatgacttat caatgggaaa agtagaaaat
    11341 cttgatatga cgaaaaatat cacttttatt gagggagatg tcgctgagaa atccttgatg
    11401 gaagagatca tgaaagctaa taaatttgat tatatctttc atttagcagc agttgctagt
    11461 gtggcagatt cagttgcccg accagtagaa acacatcgtg tgaattttga aagtgtatta
    11521 atgattttag aattgatccg caagtatcaa cctgatttaa aacggatcgt gtttagttct
    11581 tcagcggctg tttatgggga tgaaccgact ttaccaaaaa aagaagagtc cgtgattcgc
    11641 ccattgacgc cttatgcggt tgataaattc gctgcagaac aatatgtgct agattattgt
    11701 catttatatg atgtacccgg tagcgcagtt cgttttttca atgtctatgg tccaaatcaa
    11761 aatccgaatt ctccatacag tggtgtgatt tctattctcg tagatcgcta taagaaacaa
    11821 atcgtaggag aagcaacttc atttacatta tttggtgatg gaagccagtc tagagacttt
    11881 gtttatatag atgatgtaat ccaagcatta cttttagttg cgaatgagga agctgcactg
    11941 gggaaacaat tcaatgttgg aacgggtaaa gcaaccacac ttttggaatt gattcatgca
    12001 atcaatgaaa ttctcggtgt agaattgaca cttgaataca aagaagagcg ttcgggtgat
    12061 atccatgact ctctagcaga tattactaag atccagtcaa ttggctatca accgaaatat
    12121 ggtattttaa gtggaatgac taattatttg aaaactgaaa tcaattaaaa catactaaga
    12181 taagattaga gggtaaattc aggctctttg tcaataagga ctgatgagtt ttgtaaaatc
    12241 aaatctggga ta
//
LOCUS       DADLIO010000080        11666 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.083, whole genome shotgun sequence.
ACCESSION   DADLIO010000080 DADLIO010000000
VERSION     DADLIO010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11666
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.083"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            203..403
                     /locus_tag="JOX41_002377"
                     /pseudo
     CDS             203..403
                     /locus_tag="JOX41_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298761.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1115..1720)
                     /locus_tag="JOX41_002378"
     CDS             complement(1115..1720)
                     /locus_tag="JOX41_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAY6450086.1"
                     /translation="MAKIGYIRVSSQDQNLDRQLAMMEDLNIDKLFQEKASGKDIQRP
                     EFQKLLNYIREGDCVIVASLDRLGRDYEDIKNTVTFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAKKAGRYKGRPIEYSENSTDPQ
                     KRLVFKTVVDMLNQGVPVAEIAKENGLSRPTIYKIKKANDL"
     gene            1902..2237
                     /locus_tag="JOX41_002379"
                     /pseudo
     CDS             1902..2237
                     /locus_tag="JOX41_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343406.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2402..2629
                     /locus_tag="JOX41_002380"
                     /pseudo
     CDS             2402..2629
                     /locus_tag="JOX41_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613886.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            2755..3726
                     /locus_tag="JOX41_002381"
     CDS             2755..3726
                     /locus_tag="JOX41_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAY6450087.1"
                     /translation="MKTTMKDVAALAGVGVGTVSRVINGVKVKEVTKEKVMAAISELN
                     YEPDEYARGMKTNSSNTIALILPTIWHPFFSEFAYYVEEALSQKNYKLFLCNANGSAE
                     KEKEYIQMVKQSKVDGIIGITYSDIDKYVSSNLPFVSIDRHFSEQVSYVTADNYLGGQ
                     IAAQELLTRNCKNLCYVGGVSPYPNETNNRKAGFYNICEENKIAVKVLDMPEPISNLE
                     EQLLAFFSDNPEIDSIFTINDFMALDVIKAQKKLGKEAPKDFQIIGFDGVKLSLQKDY
                     LLSTIVQPIEEMAKVSVETLMAMILNEEPPKRVVVPVFFHAGETTKE"
     gene            3866..5179
                     /locus_tag="JOX41_002382"
     CDS             3866..5179
                     /locus_tag="JOX41_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAY6450088.1"
                     /translation="MKKRMLAIAAILALTAGGLAGCGSKEKSSGSSDPGEIKIWVQFS
                     DETPEGKAWAEIVNNFNDEYEGEYKAVTEYIPRSGSGGGYEDKVNAAITTNTLPDVIT
                     LDGPNTAAYAHSGVIAPLDDYLKDADMDDVLDSIIQQGTYDGKMYAFGFSESSVGVYY
                     NKSLFKDAGITEDQLPTLEDPWTWTEFQAICQKLTDKYKTPAIDMQMASGDEMLTYAY
                     TPFIWSNGGDVVNADGTKAEDYFNGKKSVEALEFIQELVEKGYTTISPIEKGFETGKY
                     AMMLSGSWTMADLEENYQEIDYGILPYPVSDATGELVSPTGSWQLAMTEKTEKKDASA
                     AFIKFATSTESSRIMSLGNSVLPIRNSTVDLIKDEVSEGMQVLIKQNQLSGHARPVVV
                     AYPQVSRAFQQAVQDISYFEENPDVQKVADSRAAEMQQAIDTSLK"
     gene            5222..6088
                     /locus_tag="JOX41_002383"
     CDS             5222..6088
                     /locus_tag="JOX41_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAY6450089.1"
                     /translation="MKDNLIGYGFLAPALLLLTIFLIIPVIMVIYYAFTDYYLLTPDA
                     RQFIGLENFKRLFADPIFVKSIWNTAKFVVWIIPVQIGAALGMALIINKNRKGNIFFK
                     VAFFAPVVMSLVVISILWLYLLNPNEGLVNTLFAKIGIASQPFLTSPKQAMYTLVFVS
                     AWQGAGYQMLLFLGGMQNIPQDVYEAAEIDGFSKFQQFRYITMPLLKPTAIFILLTTL
                     ISAFKLIIQPMVMTQGGPMNSTMTMVYYIYQTGFTDRMVGYSSSIALIFTTMIGLITI
                     AQRKLVKEDDPA"
     gene            6085..6933
                     /locus_tag="JOX41_002384"
     CDS             6085..6933
                     /locus_tag="JOX41_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006639650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAY6450090.1"
                     /translation="MTKKFGPLMIVEYCLLFLLAALFIFPMLWMVVSSMKPEADVYQN
                     LASFKAFLPSLNPANWFKTYQEVISRFSVGTYLLNSIFYGLTFACGSIIVNSLAGFAF
                     AKVNFSGKKIIFGALLALLIVPMETVLIPQFTIVNSLGLVNTRLAVILPAMASAFNIY
                     LFRNFFIAIPEEIIESAKLDGANIVKIFFHIMLPMSKPAIATVGVLSFISSWNDYIWP
                     LMVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTIATIPLIIVYIVAQKYILQGLGG
                     SGTGIK"
     gene            6947..8419
                     /locus_tag="JOX41_002385"
     CDS             6947..8419
                     /locus_tag="JOX41_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HAY6450091.1"
                     /translation="MLQKLLKANEFIEKNAQTVNQEYRNKFHLMAPIGWMNDPNGFVY
                     YQEEYHLFYQYYPYDSIWGPMHWGHAKSKDLIHWEHLPVALAPGESYDKEGCFSGSAI
                     EKDGKLYLIYTGHNVVEGQVRQVQCLAVSEDGIHFEKYAGNPIIAEDHLASVATTEDF
                     RDPKVFQRKEDYFTVVATKTADARGQIVMFHSKDLLTWEFYSVLLEGTPEQGIVWECP
                     DLFELDGKEVLILSPIQMTPQGNAYQNTNSTVAFIGTVDWQTGKFLVENFHEIDGGLD
                     FYAPQTCENEAGQRIMIAWMQMWQRKIPTNDLGHGWSGSMTLPRELRVADNQLLQRPV
                     SSIYQVIDPQERIEWAKTEENRFLLKDLVYDQHYLRLEINLKQATKLELHYAKGPDHT
                     LLLNYDVERECFTASREHMPYDLSGAEKEVLKKRSVTIPLENNCLTIEIFRDTSAIEL
                     FLNDRLTMSTTFYETEKGQDFLLLADSEVTFSLESGLINL"
     gene            8436..9308
                     /locus_tag="JOX41_002386"
     CDS             8436..9308
                     /locus_tag="JOX41_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAY6450092.1"
                     /translation="MIYGSIEAGGTKFVCAISDEEMTIKERVSFPTTTPEETIPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKVAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIEKRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
     gene            complement(9543..10925)
                     /locus_tag="JOX41_002387"
                     /pseudo
     CDS             complement(9543..10925)
                     /locus_tag="JOX41_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010726506.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            11387..>11666
                     /locus_tag="JOX41_002388"
     CDS             11387..>11666
                     /locus_tag="JOX41_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450093.1"
                     /translation="MDSFQRLSLVNQFELLAKFEDQNRSYYERKIEILREGYEYHYDD
                     EIWSDLSEPFPKEDSRFVLDVLNMYRDINFSKSKLNLDENQITNSYYTH"
BASE COUNT         3606 a         2011 c         2354 g         3695 t
ORIGIN      
        1 agaacaccac gcatagtttt tattttgaga tattctagaa tgaaacacat taagaacgaa
       61 agcaaagcaa aagacgccag aacttctact accttctaag ttttttcata tttgtttgtt
      121 atgctataca tagatctgca taattagact tgcgctgccc gttattgaag tttcaggcag
      181 cgctcttttt gggggatcga taatggaaga agaaaaaata tttgagaaac gctggcagct
      241 agcatcaagt gaacaaagag caagatacaa taatttgatc acctcctacc ccactgttga
      301 ctagacatat aaggaaaaga aatacttact ttggctgtgc cagttagata tagatacctt
      361 tgaaacattt gaagtgatcc tagataaaat taaacagaat tgatcagaaa caagcgaagc
      421 cttctctcgg ttcgcttgtt ttgctattta ttagttggct cagggcaact ctaagctcgt
      481 ttgaaagaaa accgatggat aatccccttg tttgtaccac tttagaatac atggatgtac
      541 gtattgccat tgactcctat tagttactga aaaaaaattt aaacaagttg agtattgcag
      601 ataaatagct ccagtgaggt gaataactgc tccactcaag gcaatagata gctccatcca
      661 gggcaacaaa ctgctccact ttcatattta atagatgaat aaccttctgt ataatagaaa
      721 ggcatacctt tcggtatgac aacttataca gaatgttatt ttattggttc actatcgaaa
      781 aattttggag ctttattttt ccggtatttc tcaacgaacg attagtttaa ctgtgggaag
      841 ctccagacat acgattcgag aagttacttc tcgagcagac aggaaggggg tgactgaact
      901 aaccgctgat atgagcgata cttggctgta ggaatatctt tttccggaaa aacaaacaac
      961 agcacgaggt taccttcctg tagactggga atatgttcat aaagaactaa tgaaaaagaa
     1021 tatgacattg aaactccttc atagagaata tggggtacat ggaacataga aacgaaaatg
     1081 cacggtagaa aagcgaatga atatagtata aattctacaa atcattcgct ttctttattt
     1141 tatatatggt tggtcgagag agaccatttt ctttggcaat ttctgcaact ggaactcctt
     1201 gatttaacat gtccaccaca gttttaaaga ctaatcgttt ttgcggatct gttgagttct
     1261 cagaatattc aattggtcgc cccttatatc gaccagcttt tttggccaat aatactcctt
     1321 gccgctgacg ttcacggatt ttctcacgtt cgttttgtgc aatataactt agcaatgata
     1381 aaaacatatc gaacatagca gtatctagga gttcatttcc agtattaaaa tctaaaaact
     1441 gtgcatctag tatttttaat gctacttttt tctgtttcat aaaggtaact gtatttttta
     1501 tgtcttcata atctctgcct aggcgatcca gtgatgcaac aatgacacaa tcaccttctc
     1561 ggatataatt tagtaatttt tgaaactcag gtcgctggat atctttacca ctggcttttt
     1621 cttggaataa tttatcaatg ttaaggtctt ccatcattgc caattgtcga tctaaatttt
     1681 gatcttgtga agacactcta atatatccaa tttttgccat aaaaactcct tttaaaaaat
     1741 gatataattt acatgtaaaa tttacttgta gttttactgt tatcatagca tttttaaaaa
     1801 taaattttaa gtctacttat aatttacttt ggaggttttg aatgaatgaa attaagcgca
     1861 ataaaaattc ttttggtgtt tatttaggag agcctagctc ggaacagtta aataaaggtg
     1921 aagctcgtca tgctctatgt cgaaatatat tttatggtag aaaaggcaaa ctttatcaaa
     1981 cttattacga cggtatggag gaacagctca acgcattagg attagtaact aatgctatca
     2041 tatattggaa ttcactatat ttagaaaaag tctttgaaca aattaaaacg gaagggttcg
     2101 actgttccga agaagtgtta cgcaagcaat ttccattaat tagtgatcac attaattttg
     2161 ttggcaaata tagtttccgc tatgaaaaag aattatcgaa tggaatacta cgtccgttaa
     2221 atatagagaa ttattgagaa tgttcgtctt ttggttccta ccgtgcattt tcgcacggat
     2281 gttccagata ctatttttga atgtataaaa ttgaaaacac aagaatacta ataaatcaac
     2341 gattcttgtg tttttaattt ttcactaccg tgcattttcg tttctatgtt ccatgtaccc
     2401 caatcttgaa aaattaatta aagacttaga taaagccatt gacgacttag tcgtggtgct
     2461 accggagtat caatgtttaa ccagtatccc aggtattggt cctgtttagg ctgctggaat
     2521 actcgctgaa attggtccaa ttgaacgttt ttctgatgaa ataaaattga caaagtatgc
     2581 cggcctatat tggcgacaga gtcaatccgg taaatctgaa tacgaaaatt tttttacgaa
     2641 aagcttcacg tctaatatct attttaaaat aaaaatattc ctgctaattt ggaatcgttt
     2701 ccttcttttg gtataataat acctgaaatt cttttgagag gagttgttcg tgaagtgaaa
     2761 actactatga aggatgttgc tgcgttagca ggagttggtg tgggtacggt atctagagta
     2821 ataaatggag taaaggtgaa agaggttacc aaagaaaaag taatggctgc aattagtgag
     2881 cttaattatg agcctgatga atatgccaga ggtatgaaaa cgaatagtag caatacaata
     2941 gctcttattt tacctacgat ttggcatccc ttcttttccg agtttgccta ctatgtagag
     3001 gaagctctca gccaaaaaaa ttataagctt tttttgtgta atgcgaacgg cagtgcggaa
     3061 aaagaaaaag aatatatcca aatggtcaag cagagtaaag tagacggaat tataggtatt
     3121 acctattcag acattgataa atatgtatca tcaaatttac catttgtcag tatagaccgc
     3181 catttttcgg aacaggtttc ttatgtaacg gcagataatt atttaggtgg gcaaattgcc
     3241 gctcaagaac tacttactcg taactgtaaa aacttgtgct atgttggggg tgtttcacct
     3301 taccctaacg aaacaaacaa tcgtaaagct ggtttttaca atatttgtga ggaaaataaa
     3361 atagctgtga aggtattgga tatgcctgaa ccaattagca atttagagga acaattgctc
     3421 gctttttttt cggataatcc tgaaattgat agcattttta ccatcaatga tttcatggct
     3481 ttggatgtga taaaagccca aaaaaaacta gggaaggaag cacctaagga ttttcaaatt
     3541 attggttttg atggagtcaa gctatcgttg caaaaagact atttactatc aacgattgta
     3601 cagccgatag aggaaatggc caaggtttca gtagaaacac tcatggcgat gattttaaat
     3661 gaagaaccgc ctaagcgtgt ggtagtaccg gttttctttc acgctggaga gacgactaaa
     3721 gagtaaaaaa ccggtttata acgatttttt tgagataggt tgacagaaag tgatttcaat
     3781 gatatcttaa aaccaattaa ttggaaacgt taccaattaa ttgaaaaata aaacggaaac
     3841 gtttcaaaaa ataggaggaa catcgatgaa aaagagaatg ttagcaattg cagcaatttt
     3901 agcattaaca gctggaggac ttgcaggatg tggcagtaag gagaaaagtt caggtagcag
     3961 tgatccagga gaaattaaga tttgggttca gttttctgat gaaacgcctg aaggaaaagc
     4021 ttgggcagag attgtgaaca attttaatga tgaatacgag ggtgaatata aagctgttac
     4081 tgagtatatt cctcgtagcg gaagcggcgg tggatatgag gataaagtaa atgctgcaat
     4141 tacaaccaat acccttcctg atgttattac gttagatgga ccgaatactg cagcttatgc
     4201 tcattcagga gtcattgctc cattagatga ttatttgaaa gatgcggaca tggatgatgt
     4261 attagacagc attattcagc aaggaaccta cgatggcaaa atgtatgcgt ttggtttctc
     4321 agagtccagt gtgggtgtct attacaataa gtcgctgttc aaagatgctg gaattacaga
     4381 agatcaattg ccgacgttag aagatccttg gacttggacg gaatttcaag caatttgcca
     4441 aaagctgact gataaataca aaacgcctgc aattgatatg caaatggcgt cgggagacga
     4501 aatgctgacc tacgcatata caccatttat atggtcgaat ggcggcgatg tcgttaatgc
     4561 tgatggaacc aaagccgaag actattttaa cggtaaaaaa tccgttgaag cgttggaatt
     4621 tattcaagaa ttggttgaaa aaggttacac cacaatcagt cctattgaaa aaggatttga
     4681 aactggcaaa tatgccatga tgctgagcgg ttcttggaca atggcagatt tagaggaaaa
     4741 ctatcaagag attgattatg gtattttgcc ttaccccgtt tcagatgcaa ctggggagtt
     4801 agtttcacca accggaagct ggcagttagc aatgactgag aaaacagaga aaaaggatgc
     4861 ttctgcggcc tttattaagt ttgcaaccag tacagaatct agtcgtatta tgagtttagg
     4921 gaacagtgtt ctacctatca gaaattcaac agttgattta attaaagatg aagtgtcgga
     4981 aggaatgcag gtattaatta agcaaaacca actttctgga catgcccgcc cagtggttgt
     5041 agcttatccg caagtatcta gagcattcca acaagcagtt caagatatta gctacttcga
     5101 ggaaaaccca gatgtacaaa aagtagcaga tagtcgcgct gctgaaatgc aacaggcaat
     5161 tgatacttca ctaaaataga agtttctaaa gggggccaat caagtgttaa aaaaaccgac
     5221 aatgaaagac aatttgatag gttacggctt tctagcgcca gctttgctgc tgctgacgat
     5281 ttttctgatc atacccgtaa tcatggtaat ttattatgcc tttactgatt attatttgtt
     5341 aacgccagat gctagacaat ttatcggctt agaaaatttt aagcgactgt tcgctgatcc
     5401 aatttttgta aaaagtattt ggaacacggc taaatttgtt gtttggatta ttccggtcca
     5461 aataggggca gctttaggaa tggcacttat tatcaacaaa aatcgtaaag gaaatatctt
     5521 ttttaaagta gccttttttg cgccagtcgt gatgtcctta gtcgttattt cgattttatg
     5581 gttgtacttg ttaaatccta atgaaggtct ggttaatacg ctatttgcaa agattggaat
     5641 tgcttcgcag ccttttttga ctagtcccaa acaagcaatg tatacgcttg ttttcgtatc
     5701 ggcatggcaa ggtgcaggat atcagatgct gctgttttta gggggaatgc aaaatattcc
     5761 gcaagacgtt tatgaggcag ccgaaattga tggtttttct aagtttcagc aatttcgcta
     5821 tatcaccatg ccattattaa agcccacggc gatttttatt ttacttacca cattgatttc
     5881 ggcctttaaa ctaatcattc agccaatggt aatgactcaa ggtggaccaa tgaattctac
     5941 tatgacaatg gtttattaca tttaccaaac tggatttaca gaccgtatgg taggctactc
     6001 cagctccatt gcgttaatct ttaccactat gattggttta attacaattg ctcaaagaaa
     6061 attggtaaag gaggatgatc cagcatgacc aagaaatttg gaccgctaat gatcgtagaa
     6121 tattgtttgc tgttcctttt agcggcatta ttcattttcc cgatgctgtg gatggtagtt
     6181 tcctctatga agcctgaagc agatgtctat caaaatttag cttccttcaa agctttttta
     6241 cctagtttga atccagctaa ttggtttaaa acttatcaag aggttatttc ccggttcagt
     6301 gtgggaactt atttattaaa cagtattttt tatggtttaa cctttgcctg tgggtcaatc
     6361 attgtaaact ctttggcggg ttttgccttt gcgaaggtta atttttcagg caagaaaatt
     6421 atctttggag ctttgttagc tctgctgatt gtcccgatgg agacggtttt aattccgcaa
     6481 tttaccatcg ttaattcact aggcttagtg aatactcgct tggcagtgat tttaccagcg
     6541 atggccagcg cgtttaatat ctatctgttt agaaatttct ttatcgcgat tccagaagaa
     6601 atcattgaat cagcgaaatt agatggtgca aatattgtta aaattttctt tcacatcatg
     6661 ctgccaatgt ctaaaccagc catagccaca gtaggtgtct tatcctttat ctccagctgg
     6721 aatgattata tttggccgtt aatggtctta actgacagca gcaaattttc aatgcaagtg
     6781 gcaattacta cgatcaatac tacacagcca gtttatatca atcaagtgat ggctgtttta
     6841 accattgcaa cgattccact gattattgtt tatatcgttg cacaaaaata tattctgcag
     6901 ggacttggcg gttctggaac gggtataaaa taggagtgaa tagtgaatgt tgcaaaaact
     6961 tttaaaggcc aatgagttta ttgagaaaaa tgctcaaaca gtcaatcaag aataccggaa
     7021 taaatttcat ttgatggctc cgattggctg gatgaatgat ccaaatggtt ttgtttatta
     7081 tcaagaggag tatcacttgt tttatcaata ttatccttac gacagcatct ggggaccaat
     7141 gcattggggc catgctaaaa gcaaggatct aattcactgg gagcatttgc cagtagcact
     7201 ggcaccaggt gaaagctatg acaaggaagg ctgtttttcc ggcagtgcca tagaaaagga
     7261 tggcaagctg tatttgattt atacaggaca caatgttgtg gaagggcaag ttcgacaagt
     7321 tcagtgtttg gcagtttcag aagatggcat tcactttgaa aaatatgccg gaaatccaat
     7381 catcgcagaa gatcacttag cttctgttgc aacgaccgaa gatttccgcg atcccaaagt
     7441 gtttcagcga aaagaagact attttactgt agtcgctact aaaactgcag atgctcgtgg
     7501 acaaattgtg atgttccatt ccaaagattt actaacttgg gagttttatt ccgtattgct
     7561 ggagggaact ccagaacaag gcattgtatg ggaatgccca gacttgtttg aactagatgg
     7621 caaagaagtc ttgattcttt ctcctattca aatgactcca caaggcaatg cttaccaaaa
     7681 tacgaactca actgttgctt tcatcggtac tgtcgattgg caaacaggca aatttctagt
     7741 agagaatttt catgaaatcg atggcggttt agatttttat gcaccccaga cctgtgaaaa
     7801 cgaagcaggc caaagaataa tgattgcttg gatgcaaatg tggcagcgta aaatacctac
     7861 gaatgatctg ggccatggtt ggtcaggttc catgaccttg cctagagagc tgagggtggc
     7921 tgataatcaa ttgttgcaac ggccagtttc atcaatttat caagtaattg atccgcagga
     7981 aaggattgaa tgggcgaaga ctgaagagaa tcgcttctta ctgaaggact tagtatatga
     8041 ccagcactat ttacgcttgg aaatcaattt aaaacaggca acgaaactag aacttcacta
     8101 tgcgaaggga cccgaccata cattactgct taactatgat gttgaacggg agtgctttac
     8161 tgcttccagg gaacacatgc cgtatgattt atcaggagct gaaaaggaag tgttgaaaaa
     8221 gcgcagtgtg acgattcctt tggaaaataa ttgtctaacc atcgaaattt tccgtgatac
     8281 ttcagctatt gagctttttc taaatgatcg tctgactatg agtacaactt tttatgagac
     8341 agaaaaagga caggattttc ttttgctggc agacagtgaa gtaacctttt cattggaaag
     8401 cggcttaatt aatctataga agggagagct cagtgatgat ttatggttca atcgaagcag
     8461 gcggcacaaa atttgtgtgt gccattagcg atgaagaaat gacgatcaag gaaagagtga
     8521 gctttccgac aacgacacct gaggaaacaa tacctttagt cattgacttc ttcaaacaat
     8581 accaagcaga tttagcaggg attgggattg gctcatttgg gcctatcgat atccatcgcg
     8641 attccgccac ttatgggtac attacctcga ccccgaaagt ggcatggcaa aattttgatt
     8701 tcatcggtac catgaaaaaa gaatttccga tcccgatttc ttggacaaca gatgtcaatg
     8761 cggctgccta tggtgagtat gtcttcggca gtggcaaagg attgagcagt gtcgtttact
     8821 atacgatcgg tacgggtgtt ggcggcggtg ccttacaaga agggcgcttt atcgaagggt
     8881 ttagtcatcc agaaatgggg catatgctcg tcgtccctca tccaaaagat gactttgctg
     8941 gcagctgtcc atttcatggc aactgtttag aagggatggc cgctggaccc gccatcgaaa
     9001 aacgcttagg gaaaaaagga caagaggttg cagaagatga tccttattgg gaaatcgaag
     9061 cctcctatat tgctcaatgt gcctacaata caaccttgat gttttctcca gatgtgatca
     9121 tttttggcgg tggtgtgatg aaacaacgcc atatgctgca aaacgtccac gacgcatttg
     9181 caaaattggt caatgggtat gtcgaaacac ctgagttaag caaatatatc gtgaccccag
     9241 cattagaaga caacgctgga acgctcggtt gtttggcatt ggctcgagaa gcggtcttac
     9301 attcataaac gaaaaaaggc tcttcgacat ttagtgttgg tagagaaaga tacaactgaa
     9361 aatttagtca taaccagtta ggcagagtgc ttaactggtt tttgttttac ttggaagatc
     9421 aagccttgaa tgagataagt tcttgctcga aagttatgga aatttcgata gccgtaggct
     9481 acttgtattg tgcaatagtt ttttacaaaa aaagggggtg cggatatttt ttttggacct
     9541 ttttaacaaa tatatctttg cttcttccga tattgaagag ggcttagcct tcctaaagat
     9601 aacttaattc gttgattatt ataccaatga atataatcat ccaatttgtt tataaactga
     9661 ttgattgttg tattcttcca gtcacgttga taaaacatct cgttttttaa tcgtccaaag
     9721 aaaccttcgc acgctgaatt atctggtgaa taactctttt tagacataga gtgaagcaag
     9781 ttggctttgt tccaatagtc caactaacaa tagcaccatc gtaacaatcg acaagtggtg
     9841 ataagtagat tttccctgcg agaattctaa attcagtaat atctgttaac catttttcat
     9901 ttggcttctt tgctttaaaa ttccgattta ataaattggg gtgtgcagga gaaatttccc
     9961 cagcatacga agaatacttt tttcgtctag aaaatttaac aaatagattt tcctcagtca
    10021 tcaatctacg tacaactttt tcagaaagct ttttacccat attttttaaa gcttggtgaa
    10081 ttctacggta accatacgca cagaagttat gattgaaaat cgtgataatt aatttgacgt
    10141 tctttgtaat acttatctgg tttctcaagt gcttgttttt gataaaaata gctgctttta
    10201 ggaaactgga gctgttgaag aagctctttc aaggtgaact gatttcgtaa ggcatcaatc
    10261 aatatcgttt tttcttgatt tgatagacaa agaagattga cgcctttttc tttttttagc
    10321 agttcagccg ctccttcgag taatgctttt tcgagctgta attggtgtac ttgtttttgt
    10381 aagtcttcta cttcctttaa aagtagctct ttttgttttt cctgattttt taaagtcata
    10441 cacaatggaa aatcctttcc aagaaccgtg tttttccatt gatatagagt aactctacta
    10501 attcctccag attcggctaa atttttccta ttagtttgcg gtttatagaa ttttttcaac
    10561 acagcttctt tttgatcttg tgttaacttt accgcacttt ttcggagttt tctagctcct
    10621 ggtgcaagtt cttcacaccg ctgccgcaag gactctctat taggataacc aagcatgcga
    10681 atggttcgtg cataacattg accatattca aaataatgat tcaccgctat tcgtttttgt
    10741 tcttcagaat actttgattt ttttcggtgc tcctgatgga gctctccgga ttccaaatac
    10801 tctttatacc atttccgtag tgcaccaatc gacggatacc ctaattctcg aatggttgca
    10861 gcataagagc aatcgtattt taaaaataac tgaattgccc ttacacgctc tttgtgggaa
    10921 aacacacgga cattcctcct aagtttattt tttcgtccag gattatgtcc gcaccccctt
    10981 gctttctgat gacttattct ggttctttga gtgtcaatgc atagatgtga tgtagctagt
    11041 tagaaaaaaa ttttgaatac tctttttttc tttcagactc ctttttaagt aagattttga
    11101 agtgtgagtt acggggtcag aaacttaaaa gtttttgatc ctttattttc aagtctgatt
    11161 tggcagcttt tcggcagctc atttatttat ggtcagaaat agatgctgaa attttaatct
    11221 attagcaaat agtccagaac gtatgaagag gagtcggata tcatttgtca ttaacaccat
    11281 aaatatttat aaaattcgtg ttcacctaca attaaattta atatataata ttcgttgtaa
    11341 gggcttataa ttttttgtta atgaacaaga taggaagaaa catttaatgg acagttttca
    11401 gagattgtca ctagtaaatc aatttgagtt attggctaaa tttgaggacc aaaacagatc
    11461 ttattatgaa agaaaaatcg aaatattgag agaaggttac gagtatcatt atgatgatga
    11521 aatttggagt gatctttctg agccatttcc gaaagaagat tctcgatttg tattagatgt
    11581 attgaacatg tatcgagata tcaattttag taaatcaaag ctaaacttag atgaaaacca
    11641 aattactaat tcatactata ctcatt
//
LOCUS       DADLIO010000081        11546 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.084, whole genome shotgun sequence.
ACCESSION   DADLIO010000081 DADLIO010000000
VERSION     DADLIO010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11546
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.084"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(203..1654)
                     /gene="cls"
                     /locus_tag="JOX41_002389"
     CDS             complement(203..1654)
                     /gene="cls"
                     /locus_tag="JOX41_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAY6450094.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            1995..4661
                     /locus_tag="JOX41_002390"
     CDS             1995..4661
                     /locus_tag="JOX41_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAY6450095.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            5025..5777
                     /locus_tag="JOX41_002391"
     CDS             5025..5777
                     /locus_tag="JOX41_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAY6450096.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            6230..7618
                     /gene="ltrA"
                     /locus_tag="JOX41_002392"
     CDS             6230..7618
                     /gene="ltrA"
                     /locus_tag="JOX41_002392"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAY6450097.1"
                     /translation="MRRPQKTRKLGYHQRASVEHEGYDEVRSTSCGEQRKQDGVENLF
                     GRILDRNNLNQAYLQVVRNKGAAGADGMTVDQLLPYLKEHREELLSNLRQGNYKPQPV
                     LRVEIPKPNGGVRKLGIPTVIDRMLQQAINQVLQPLFEPEFSDNSYGFRPNRSAHDAV
                     KKAKSYYEQGYRYVVDIDMKAYFDTVNHDKLMYFIERKVKDKQVLKLIRQYLMSGVME
                     NGLITTTEEGTPQGGNLSPLLSNIYLNEFDQVLENLGHKFVRYADDCNIYVRSKRAGQ
                     RVMKKSIQFLEEQLKLTVNREKSAVGSPLKRKFLGFCILPTKKGIKIRPHAKAKQRVK
                     SKLKQLTKRNRGRSIQLILKEIKQLMTGWINYYGIGEMKEFMRELNGWLKRRIRQYIW
                     KQWKNPRTKRKNLIRLGIDKAKAYEWSNTRKGIWSVSKSHILHRSLTDKELARQGYED
                     ISLKYQFVHSTY"
     gene            complement(7698..8852)
                     /locus_tag="JOX41_002393"
     CDS             complement(7698..8852)
                     /locus_tag="JOX41_002393"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HAY6450098.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYSLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            9037..11478
                     /locus_tag="JOX41_002394"
     CDS             9037..11478
                     /locus_tag="JOX41_002394"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HAY6450099.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
BASE COUNT         3770 a         2093 c         2522 g         3161 t
ORIGIN      
        1 gaaagaggtc gtgagcctgc cgtccagctc cgagtcacaa ggaacaagtt caaaaaacag
       61 cttctcatgt ttgttgaata ttgtgacttg tgaccgagga gttggcagga gaacaccgtt
      121 tgttcggaag aagggactgt gacaagattt ttgtcacagt ccctttaatc ttagtatatt
      181 tttctctact tgaataaaaa aattatagga ttggagaaaa taatcgagaa atttgttgct
      241 tgaataatag ccagttagac atttccttga ctgtttcagt tgtcatggat gaacaatgtg
      301 tctcatcttc tttgaactga gtagcaagtt cttctaaaaa ctcaggatcg taaatgacag
      361 cacttgtttc aaaattcaat cggtagctac gaatatcttg atttgctgaa cctaccatgc
      421 agatttcatc atccattatc aatgtttttg catggaggaa gccgttctca tagacaagga
      481 tttgtacatt ttccttgatc agctgccgag cataatattg tgttgctcga taaataaaag
      541 gatgatccgg tttgttggga atcatgattt tcacatctac accagaggca gttgcgattt
      601 ttaaagcagc aatgacactt tcatcaggaa caaggtaagg tgtctgtatc caaacacgtt
      661 ttttagcaga agtaatcaat ttgataaatg aaagcttgat ttgttccctt tcgttattcg
      721 gtccgcttga aacaagctgg atggatgtat cagcaagctt agattcatct cgatctgctt
      781 ttttaaagaa ataattcaaa tgatagccga cctttttttc ttcaggtacc gagacgttcc
      841 agtctgttaa gaagcgaagc tggagcaaag aagaagcggc accgaaaatc cgtatatgcg
      901 tatcgcgcca atagccgaat ttttttgttg tatttacata ttgattggca atattgaaac
      961 caccggtata actaatcttt ccatcgatca caacgatttt tcggtgatca tggtaattca
     1021 atcggaaacg aagtaatgcc ctttgtgagg taacaaatgt atggacatgt ccaccatttt
     1081 tgattagacg attgaaatct tttgcttttg tgccatgaga gccaaatgca tcatataata
     1141 ttcgaacttc cacgccttct gcggcttttt cttctaaaac atgtaagact tgctggccga
     1201 tattatctgt cacaaatgcg taatattcga tatggatcga atgtttggct ttttttagat
     1261 cttgaagcag tgaatccaat ttctcttgtc cgtctgtgag aagagtgaca gaattcattc
     1321 ttgtcagcgg catacgattt aatgaagaga agaagtcaac aaattgctgt ttgtctttat
     1381 cgcccatgtc aggatcgtaa tgttcaatgg tatctcctct aaaagactga aagttttcta
     1441 attctttcaa gtcactttgt cggagataga attttttctt atccgttaat ccacgtccga
     1501 aaaataaata taatacaaag cccaccccag gaagggcaaa caatactaag agccatgccc
     1561 aaatggctgc tacatctcgg ggtttgatca aaatagccac caaagcaata agtgcattta
     1621 atagataaag ggcggttata atactagata ccacaaaaat gttcctcctt acatacaata
     1681 acattagtat agcatgatag aagaaagaag cctaccaagg tgaatatact tttcactcct
     1741 ttcatgaaaa tgtaggtaaa tcgggctaaa gtagttgctt tttgtaggtt aataaggtag
     1801 gatattagta cagttgaata tctccttagg ggagtaaccg gcaacgtttg ttgcgataat
     1861 atcaacagta agttaaccaa atggttttct ggtattgtat gaaatggtga gacctaagac
     1921 aaatgcgtat ttgtcttagg tctctttttt ttcagacagg actagggcca agatcaaaaa
     1981 atgggggatg aaatttggaa aacaaggaac aagcacaaca agcggtctat aaagaaacga
     2041 tcgactcgtt gatgcagcaa acgcagagct caaccgatgg attgagcacc acgcaagcga
     2101 aggaaaaatt agaaagagat ggcttgaacc agctaaaaga aaagccgaag aagccaactt
     2161 ggaaattgtt cttagaaact ttcaaagatg caatggttat cgtattgctg attgtcgcac
     2221 tgattcagat ggtcatgggt gactacatcg aattcttagt tatttttgca gtattgatgt
     2281 tgaattctat aatcagtgtt gtccaaacaa aaaaagcaga aggttcttta gaagcgttga
     2341 aaaacctttc agcgcccgat gctcgagtga ttcgtgatgg taaggaaaaa acgattccgg
     2401 caaacgaact tgtggtagga gatatcgtgt tgttagacgc aggcgattat gtacctgctg
     2461 atggacgttt actagatgcg ggatcattaa aagtagatga aggtatgctg acaggagagt
     2521 cgacttctgc agaaaaagaa gtaacggata tcacaagtac ggtaccaatc ggagatcgta
     2581 caaatatggt attcagtgga acgatcgtaa cttacggacg cggtaaattc ttagtgactt
     2641 caactgggaa taatacggag atcggacaag ttgctggcct tttggaatca acaactgagc
     2701 aagtcactcc gttacaacga ggtctggata aattcagtaa aaaactaagt ttggctattt
     2761 tggcattgtc tttattgatt ttaggtatcc aactgtttcg tatttatctt ggagaaggta
     2821 caggagatat gactgcagat atcgtcagcg cagtgatgtt tgccgtagcc gtagccgtag
     2881 ctgctattcc agaagcatta cagtctatcg taacaatcgt gttatctttg ggaacgaata
     2941 aaatggcaaa acgtcatgcc attattcgga agcttccagc agttgaaaca cttggttcga
     3001 caagtatcat ctgtacagat aagactggta cattgacaca aaacaaaatg acagttgttg
     3061 actacttttt aggtaatggc gatactgggg atttcacaaa tgacccttca aaatggacag
     3121 ctgacgaacg tcgcttgatc gaaatcagtg ttttagcgaa tgatgcatcg atcagtgaag
     3181 acggtactaa attgggcgac cctacggaag tagcgtttat cgactttagt gaaaaattaa
     3241 accagcctta tcaggaaatc cgaaacaact acccaagaca agcagaactt ccttttgact
     3301 cagatcgaaa attaatgtct actggacaca caattgataa caaaaattac ttgtttgtta
     3361 aaggcggacc agatatcgtc ttccaacgca gtaaaaaagt attgctaaat ggtgaagtcg
     3421 ttccgatgac ggatgaattg atgaaaaaat tccaagagca aaatgaagct ttttcaacac
     3481 gcgcattacg tgtactagct tttgcttacc gtccacttga taattttgat ttatcatttg
     3541 aagatgaaga cgatttgatc cttgttggtt tgcttgctat gatcgatcct ccacgtgctg
     3601 aagtgactca ggcggtaaca gaagcaagaa gtgcaggaat caaaacaatc atgattactg
     3661 gtgaccacaa aacaacagct gttgctatcg caaaacaaat cgggattttt gaagaaggaa
     3721 acctggcttt gaccgggacg gaactagatg aattgacaga agatcaacta aacgaagttt
     3781 tagaaaaagt cactgtttat gcacgtgttt cacctgagaa taaaattcgt atcgttcgtg
     3841 cttggcaaaa taaaggtcat atctcagcta tgacaggtga tggtgtaaat gacgcaccag
     3901 cattgaaaca agcagacatc ggaattgcta tgggaacggg tacagatgtg gcaaaagatg
     3961 cagcagcgat ggtattgacg gatgataact ttgcttctat tgtcagcgca gtagaagtag
     4021 gacgtaatgt gtttgataat atcaagaaag ctatttctta tctatttgca ggaaatttag
     4081 gtgcgatcat tgcgatcatc tttgccttag ttgctgactg gtccaatcca tttacagcat
     4141 tacaactgtt gttcatcaat ttagtcaatg attcactgcc agcaattgca ttaggtacag
     4201 aaaaagctga acctgctacg atgaaccgcc cgccaagaga tccaaattca ggaatcttta
     4261 cggacaaaac attgatttct gtaacgtatc gtggtgtgct gattgggatt gctgttatct
     4321 ttgctcaatg gcttggcatg cagcattcac ctgaattcgg tgtagccatg tcattttcaa
     4381 cattgatttg gtgtcggaca ttgcaaacat tcccagcacg ttcaaacaca caaacagcta
     4441 tccaagcagg gttcttctct aacagaagtg tcttactagc tgtagttgta tgtagcgcgc
     4501 tttactgctt aacaatgatc ccaggactga aagaagtctt ctctatccca tcagcatttg
     4561 gattgacaga agtctttaca tgtatgggaa tcgcacttgt gacaattgtt ttgatggaaa
     4621 tcactaaatt gatcattgta cgagtacaag gaaataaata aaacgaatca acgaggttgt
     4681 gagcctgccg tttaattctg agtcacaagg tgcaatttca acaaacagct tctcatgttt
     4741 gttgaatatt gtgacttgtg accgaagagt tggcaggaga acaccgttta aggaagaagt
     4801 tgtaaaatca gcattttgag ctaatactga gggtcatctg attggacact gtttattcgg
     4861 aaagagggac tttgacacga ctttggtcac agtccctttt tttatttatg atagacggaa
     4921 agccaatcat tttattattc atcaaaagag atagaataga taaaagagga gaatgattta
     4981 ttccgaaaag tgaaaacata taacaaaaaa ttagaggaaa tcaaatgaat gaaaaagaat
     5041 gggatgaatt tgctgaagaa tattatgaaa tccagcaaga atcgcaagta actattgctg
     5101 aagatgtaaa aaattatctg aaaacggaga aagtcctgcc tgctgaaaca gcagcagacg
     5161 ttgctggagg atctggcaga tttctttcct tagcaaaaga aattaatcgc tatgatttga
     5221 tcgatttttc ttcaggaatg ctagaaaatg caaaaaaaga agcagaaaaa aatgagttgc
     5281 caaatgtttc ctttatcaaa cagtcgttag aagaatttat ccaatcaaat gagacatatg
     5341 aaatggtttt tacagcagca aatccagcat tggtacatct tattcaatta gaaaaattga
     5401 tgaaaaagtc aagcaaatgg tgcgtgataa tcagagtagt ggaatcaatc gatgatgttt
     5461 tttatcctat cgaaaagcaa ctaggaatga tagaagaaga tcctaataca tcgccagttg
     5521 taatggatca atttgaaaca tacttaattg atgaaggatt caaagtgaag aaaaaagatt
     5581 ttacttattt tacacaggaa tcaattactg aagaattgat gaagctatac tatgacgcgt
     5641 acgcaaaaga tcctgttgtg accaggtaca ttcgcaaact attcagtgaa aaacgagaaa
     5701 tccttagtac gactaagctg acctatagac tgctcctttg gtccgcagat aaaaaaagaa
     5761 cctttcacga ctcgtgaagg gttcttttta tgatgtgcgc cctgcatggg tgaaaacttg
     5821 gtggtgaaag tccactacag gcttggcagt aggaactgtt agcgaaagac aaggcggcaa
     5881 tcgtgaggtt gtggctgaag gaagtcggac gcaaactcct gaactgacga acagaaacta
     5941 gatacaaggc tgaattaggt cggataagtc ttcatcacaa gacaaagtcc aatactgccc
     6001 gaaacctata cagtaaatct agcagttaca tgggaggaaa gttttcactc ttaccggggg
     6061 agatctcatg agggtgttgt gggcgttgaa tgaaaacaaa ccagcacaac gatcatggcg
     6121 acatgatggt gaatcatgag aagtcagccg aggtcatagt agtaacgaca ctgaccgtta
     6181 cgaaggactg aacaataaga atcttgaata atttaggagg tgtgagaaga tgcgacgacc
     6241 gcagaaaaca agaaaacttg gctatcatca aagagctagt gtggaacacg aagggtatga
     6301 tgaagtgcgc agcacttctt gcggtgaaca gaggaaacaa gatggtgtag aaaatctgtt
     6361 tgggagaatt ctagatcgga ataatctcaa tcaagcgtat cttcaagtag tcagaaataa
     6421 aggggcggct ggtgcagatg ggatgaccgt cgatcaactg cttccttact tgaaagagca
     6481 ccgcgaggaa ttactatcca atttacgcca agggaactat aaacctcagc ctgttttgcg
     6541 agtagaaata ccgaaaccaa acggcggtgt aagaaaacta ggaattccca cggttattga
     6601 tcgtatgctt caacaggcaa tcaatcaagt gttacaaccg ctatttgaac cagaattctc
     6661 agataatagt tatgggtttc gcccaaatcg cagcgcacat gacgcagtga agaaagcaaa
     6721 atcttattat gaacaaggtt accgatatgt ggtggacatt gatatgaaag cctactttga
     6781 caccgtaaat cacgataagc tgatgtattt cattgagcgg aaagtaaagg acaaacaagt
     6841 cctaaaactg atccgtcaat acttaatgag tggtgtaatg gaaaatggac tcatcacaac
     6901 aactgaagaa ggaacgcccc aaggaggcaa tctctctccc ctgttaagta acatctacct
     6961 gaacgaattt gatcaagtgc tagaaaatct aggacataaa tttgttcgat acgccgatga
     7021 ctgcaatatc tatgttagaa gcaaacgagc aggacagcgt gtgatgaaga aatccattca
     7081 atttctcgaa gaacaactaa agttgacggt aaatcgagaa aagagtgcgg taggaagtcc
     7141 attgaaacga aagtttcttg gattctgcat tctgccaaca aagaaaggta ttaaaattcg
     7201 ccctcacgca aaagcaaaac agcgtgtgaa aagcaagctc aaacaactca ctaaaagaaa
     7261 ccgtggaaga agtatccaac ttattttaaa agaaatcaag caactaatga ctggttggat
     7321 caactactat ggaattggtg agatgaaaga attcatgagg gagttaaacg gttggttgaa
     7381 gcgaagaatc agacaatata tttggaaaca atggaagaat ccaagaacca aaagaaaaaa
     7441 tctgattcgt ttagggatcg ataaagcgaa agcgtatgaa tggtcaaata caagaaaagg
     7501 tatttggtca gtctccaaaa gtcatattct tcatcgatca ttaacagaca aagaactggc
     7561 ccgccaagga tatgaggaca tctccttgaa gtaccagttc gtacactcaa cttattgaac
     7621 cgccgtatac gggtccgtac gtacggtggt gtgagagggg cggaaggtca gttggctttc
     7681 ccctctactc gattttatta tattttgtag taacgaatat cattttcgat ctttgtaatc
     7741 gaaaaaggta catctgaagt atattctgca cattctccgt gttcaggaag cgtctcactg
     7801 aaaatcgttt catattcgtc aacagtgatc cgtgttcgag aatctagcat ctcttgatga
     7861 gattgtgcga agagatattc ttgatagttt tcttccagat aacctgtaaa aaattcactt
     7921 actgcaccag aaccgtagct gaatagaccg atgcgatctc ctggctgtag tgatttcgaa
     7981 ttttccagta gagaagttag ccccaggtat aatgaaccag tgtaaagatt accgattcgt
     8041 cggctgtaac ggatgctttc ttcatagcga gccataagac gttcctgatt ttcttcgtct
     8101 gtttggtcta atacgctttg caatgccttt tttcccatct tagtatacgg aatatggaaa
     8161 gcaatcgcct gataatcttc gagtcctcga cccgacaatt ctttatgtcg attccaaact
     8221 ttttggaatg attcgatata cgtagaatta gataaaggac catcaacaac aggaaattcg
     8281 ctataatctg gacgccagaa atcatagata tcttctgtca gaaatacgct gtcgtcttca
     8341 atcgataaaa tacgcgggtt ttgagtgatc atcatcgcaa cagcaccgac accttgcgtc
     8401 acttcaccac cgcttgccaa gctgtaacga gcaatatcac ttgctatgac tagtactttt
     8461 cgttctggat gatttttgac atattctttc gccatgtgca aagctgcggt gccaccgtag
     8521 caagcctctt ttacttcaaa agaacgagca aaagattgga ttttcagtaa atggtggata
     8581 attaccgcac tcgcttttga atgatcaatc ccggattctg ttccgacgat gaccatgtcg
     8641 attagctcac ggtctttttc tgttacgatt ttgctggcag catttgctcc tagtgtaatg
     8701 atgtcttcat ttgcacgatt gactgccatt tggtcttgac caatccctat atggtatttt
     8761 gcaggatcat ccccacggct ttctgccaac tctgtcatat ctaaatataa attaggaata
     8821 aaaaaggaaa gacgatcaat ccctattttc atttcaacac ctctttactt atgataaaaa
     8881 acttacttta ctaaggtatc ataaaaagat taaaagaaat ataaaaaaga gaatatttaa
     8941 ggattgttaa aatttaatct tagaaaaaaa taactggaac aagagctatt tgtttttaca
     9001 gcaaagaatg gtatattttt gtaggaggtg gcttacttga aagaagtcgt tatgatagat
     9061 gctgcaagaa cgccgatagg aaagtatcgc ggaagtttaa gtccatttac tgcagttgaa
     9121 ttaggcacac ttgtgactaa aggattatta gataaaacaa aactgaaaaa agataaaatc
     9181 gatcaagtaa tatttggaaa tgtcctgcaa gctggtaatg gtcaaaatgt tgccagacag
     9241 attgctttga acagcggtct ccctgtagat gtcccagcaa tgacgatcaa tgaagtttgc
     9301 ggatctggta tgaaagcagt gatcttagca cgccagctga tccaattagg tgaagcagaa
     9361 cttgtgatag ccggcggaac agagagtatg tctcaagcac ctatgctgaa acagtatcag
     9421 tcagaaacaa atgaatatgg tgaaccaatt tccagtatgg tcaacgacgg attgactgac
     9481 gcattttcaa atgcacatat gggattaacc gcagagaatg ttgcaacaca attttctgtg
     9541 agcagagaag agcaggatcg ctatgccttg tcgtcccagt tgaaagcagc acatgctgtc
     9601 gaagccggtg tattttctga ggagatcatc ccagtcaaga tttctgatga agacgtgtta
     9661 tctgaggatg aagcagttcg tggaaatagt acattggaaa aactgggcac gttacgtaca
     9721 gtattctcag aagaaggaac tgtaacagca ggaaatgctt ccccgttgaa tgacggtgcc
     9781 tctgtggtga tccttgcatc caaagaatac gcagaaaata ataatctgcc ttatttagca
     9841 accatcaaag aagtagcgga ggtcggtatt gacccaagta tcatgggaat cgctccaatc
     9901 aaagccattc aaaaattgac agatagatca ggaatgaatt tatcaacaat cgatcttttt
     9961 gagatcaatg aagcatttgc agcttcttct atcgtagtta gccaagaact gcagttagat
    10021 gaagaaaagg tcaatatata tggaggagca atcgcattag gccatccaat tggtgcaagc
    10081 ggtgcacgta tcttgactac attagcttac ggattgcttc gtgaacagaa gagatacggt
    10141 attgcttcat tatgtattgg tggaggttta ggcttggcag tcttgttaga agcgaatatg
    10201 gagcaaacac ataaggatgt gcaaaaaaaa aagttttatc agcttacgcc atctgaacgg
    10261 cgcagtcaat taatagaaaa aaatgtattg acacaagaaa ctgcgttgat ttttcaggaa
    10321 caaacacttt ctgaagagct ctccgatcac atgatcgaaa accaagtgag tgaagtggaa
    10381 atcccaatgg ggatcgcgca gaattttcaa atcaatggca agaaaaaatg gattccgatg
    10441 gcaacagagg aaccatctgt cattgcagct gcaagtaatg gtgcaaaaat ctgtggaaat
    10501 atctgcgcag aaacacctca gcggctgatg cgagggcaaa tcgttctatc aggaaaatcg
    10561 gagtatcaag cagtgatcaa tgcagttaat catcgaaaag aagagctgat tctttgtgca
    10621 aatgaaagtt atccttcaat cgtgaaacgc gggggcggtg ttcaagatat ctctactcgg
    10681 gaattcatgg ggagtttcca tgcatactta tctattgatt ttttagtgga tgtaaaagat
    10741 gcaatgggcg ctaacatgat caactcgatt cttgagagtg tggcaaacaa gttacgggag
    10801 tggttccctg aagaagagat tctattcagt attttaagta attttgctac agaatcattg
    10861 gcttctgcct gttgtgaaat cccattcgaa cgcttaggga gaaacaaaga aatcggtgaa
    10921 caaattgcca aaaaaatcca acaggcaggg gaatatgcga agcttgaccc ttaccgtgca
    10981 gcaacgcaca acaaagggat catgaatggt atagaagctg tagtggcagc tacaggaaat
    11041 gatacacgtg cggttagcgc ttcgatccac gcctacgcgg caagaaatgg attataccaa
    11101 ggattaacag actggcagat caaaggggat aaactagttg gaaaactaac ggtgcctttg
    11161 gctgttgcca cagtaggcgg agcttccaat atcctgccaa aagcaaaagc atctttagct
    11221 atgttagata ttgattcagc caaggaacta gcacaagtaa ttgctgcagt agggttagct
    11281 caaaacctgg ctgctttgcg tgcattagtt acagaaggaa tccaaaaagg ccacatggga
    11341 cttcaagctc gttcattagc gatctcaatt ggggctattg gtgaggaaat cgagcaagtt
    11401 gcgaaaaaat tacgtgaagc agaaaagatg aaccagcaga cagctataca aatattggaa
    11461 aaaatccggg aaaaataaaa aagcaatatc tttagaagaa taaagcaaga tttacagtta
    11521 ttttatttac tgcagatctt gctttt
//
LOCUS       DADLIO010000082        11445 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.085, whole genome shotgun sequence.
ACCESSION   DADLIO010000082 DADLIO010000000
VERSION     DADLIO010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11445
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.085"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(<1..53)
                     /locus_tag="JOX41_002395"
     CDS             complement(<1..53)
                     /locus_tag="JOX41_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HAY6450100.1"
                     /translation="MLVFQMRNVDKTSTVLK"
     gene            complement(102..341)
                     /locus_tag="JOX41_002396"
     CDS             complement(102..341)
                     /locus_tag="JOX41_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013646120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HAY6450101.1"
                     /translation="MIVGNLGAQKEKRNDTPISAKKDIMGDKTVRVRADLHHIIKIET
                     AKNGGNVKEVMEIRLRSKLKSVLIVHYLKILYNRN"
     gene            complement(475..1692)
                     /locus_tag="JOX41_002397"
                     /pseudo
     CDS             complement(475..1692)
                     /locus_tag="JOX41_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
     gene            2183..3121
                     /locus_tag="JOX41_002398"
     CDS             2183..3121
                     /locus_tag="JOX41_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HAY6450102.1"
                     /translation="MKKIDEKLAAEISLKKPAVSNSRLSNSRLSGQTLGKSQPALSFD
                     AMTIVGNLNKTNAKKLSDFMSVEPQIRLWDILQTKFKAKALQEKVYIEYDKVKADTWD
                     RRNMRVEFNPNKLTHEEMIWLKQNIIDYMEDDGFTRLDLAFDFEDDLSDYYAMTDKAV
                     KKTVFYGRNGKPETKYFGVRDSDRFIRIYNKKQERKDNADVEVVSEHLWRVEVELKRD
                     MVDYWNDCFNDLHILKPAWATLEKINEQAMVYTLLHEESMWGKLSKNTKTKFKKLIRE
                     ISPIDLTELMKSTLKANEKQLQKQIDFWQREFRFWK"
     gene            3251..3898
                     /locus_tag="JOX41_002399"
     CDS             3251..3898
                     /locus_tag="JOX41_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A-7 chloramphenicol O-acetyltransferase"
                     /protein_id="HAY6450103.1"
                     /translation="MTFNIIELENWDRKEYFEHYFNQQTTYSITKEIDITLFKDMIKK
                     KGYEIYPSLIYAIMEVVNKNKVFRTGINSENKLGYWDKLNPLYTVFNKQTEKFTNIWT
                     ESDKNFISFYNNYKNDLLEYKDKEEMFPKKPIPENTIPISMIPWIDFSSFNLNIGNNS
                     SFLLPIITIGKFYSENNKIYIPVALQLHHSVCDGYHASLFMNEFQDIIHRVDDWI"
     gene            complement(4591..5529)
                     /locus_tag="JOX41_002400"
                     /pseudo
     CDS             complement(4591..5529)
                     /locus_tag="JOX41_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
     gene            complement(5529..6146)
                     /locus_tag="JOX41_002401"
     CDS             complement(5529..6146)
                     /locus_tag="JOX41_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAY6450104.1"
                     /translation="MAKIGYARVSSKEQNLDRQLQALQGVSKVFSDKLSGQSVERPQL
                     QAMLNYIREGDIVIVTELDRLGRNNKELTELMNQIQIKGATLEVLNLPSMNGIEDENL
                     RRLINSLVIELYKYQAESERKKIKERQAQGIEIAKKKGKFKGRQHKFKENDPRLKHAF
                     DLFLNGLSDKEVEEQTGINRRTFRRYRARYNVTVDQRKNNEKRDS"
     gene            complement(6678..8168)
                     /locus_tag="JOX41_002402"
     CDS             complement(6678..8168)
                     /locus_tag="JOX41_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepR"
                     /protein_id="HAY6450105.1"
                     /translation="MNIPFVVETVLHDGLLKYKFKNSKIRSITTKPGKSKGAIFAYRS
                     KSSMIGGRGVVLTSEEAIQENQDTFTHWTPNVYRYGTYADENRSYTKGHSENNLRQIN
                     TFFIDFDIHTAKETISASDILTTAIDLGFMPTMIIKSDKGYQAYFVLETPVYVTSKSE
                     FKSVKAAKIISQNIREYFGKSLPVDLTCNHFGIARIPRTDNVEFFDPNYRYSFKEWQD
                     WSFKQTDNKGFTRSSLTVLSGTEGKKQVDEPWFNLLLHETKFSGEKGLIGRNNVMFTL
                     SLAYFSSGYSIETCEYNMFEFNNRLDQPLEEKEVIKIVRSAYSENYQGANREYITILC
                     KAWVSSDLTSKDLFVRQGWFKFKKKRSERQRVHLSEWKEDLMAYISEKSDVYKPYLVT
                     TKKEIREVLGIPERTLDKLLKVLKANQEIFFKIKPGRNGGIQLASVKSLLLSIIKVKK
                     EEKESYIKALTNSFDLEHTFIQETLNKLAERPKTDTQLDLFSYDTG"
     gene            complement(8211..8510)
                     /locus_tag="JOX41_002403"
     CDS             complement(8211..8510)
                     /locus_tag="JOX41_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450106.1"
                     /translation="MNHDECKTYIKNSLLEIRKLANIYTLETFKKELEKRNIYLETKS
                     DKYFSSEGEDYIYKLIENNKIIYSISGKKLTYKGKKSFSKHAILKQLNEKANQVN"
     gene            complement(8876..9160)
                     /locus_tag="JOX41_002404"
     CDS             complement(8876..9160)
                     /locus_tag="JOX41_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAY6450107.1"
                     /translation="MELAFRESLKKMRGTKSKEKFSQELEMSRSNYSRIESGKSDPTI
                     KTLEQIAKLTNSTLVVDLIPNEPTEPEPETESEQVTLDLEMEEEKSNDFV"
     gene            complement(9679..10164)
                     /gene="vanZ"
                     /locus_tag="JOX41_002405"
     CDS             complement(9679..10164)
                     /gene="vanZ"
                     /locus_tag="JOX41_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HAY6450108.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(10317..11228)
                     /locus_tag="JOX41_002406"
     CDS             complement(10317..11228)
                     /locus_tag="JOX41_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HAY6450109.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
BASE COUNT         3508 a         2004 c         1742 g         4191 t
ORIGIN      
        1 tgtttcaaaa cagtagatgt tttatctaca ttacgcattt ggaataccaa catgacgaat
       61 ccctccttct taattacaaa tttttagcat ctaatttaac ttcaattcct attatacaaa
      121 attttaagat aatgcactat caacacactc ttaagtttgc ttctaagtct tatttccata
      181 acttctttta cgtttccgcc attctttgct gtttcgattt ttatgatatg gtgcaagtca
      241 gcacgaacac gaaccgtctt atctcccatt atatcttttt ttgcactgat tggtgtatca
      301 tttcgttttt ctttttgtgc gcctaaattt cccacaatca ctcacttctt tctatttctt
      361 cttattctta ttttatcatc aacaatcaca aatcacttgt gatttgtgat aagtgatttg
      421 tgataagtga tttgtgatta atatataaaa gccctcttta aagggctttt atgtttattt
      481 tgagaaagat ataaaatcaa tatatccctt ttccccaatt tttacaacgg cattgtaggg
      541 ctttttctct ttgtttttga ttccttttac cagggtttct tttccctcca gtaattcttt
      601 tacattcgtt ttggttagtt ttttctttct aaaatgttca gctaaagtaa acttacattc
      661 aggataattt gaacaaccat aaaacgattt ttttaataca atattgttgc cacacttagg
      721 acattttcct acaatacttt tttctgcttc tttttctttc tgttcctggt aatcagaaaa
      781 atttagtttt tctatatcgt taggtacagc ttccagtaaa tgaacaatga attttttgat
      841 attcgtaata aagttctctt gattgccttc tcttttaccg atttttttta aatacgtttc
      901 ccatttagcc gtcatttcag cactcgttaa aaggtgctga ctttcaactg cctggcacaa
      961 taattttcct ttttcagtta caacaagctt attcttaatc acttggatat attctttttg
     1021 ttttaacgct tcaataatac ttgctcttgt cgcttctgtt ccaatcccct caacttcttg
     1081 taaaatcttg attgcttctt catcatcaac cgttttattc gccgttttca tagcagttaa
     1141 taatgtaccc tctgtaaaag cttttggcgg ttgcgtttct ttttcaacac tcttaacacc
     1201 aacttcggca cgttcgccaa tgataacgag tggtaacgtt tgaacgtcct ctttttcttc
     1261 tttggtttgt tgtttgaaaa gaattttcca cccttcttgc tttggtgtct ttccgatcga
     1321 ttgaaacagc aaatcagcta ctttcgtttg tatcttggtt tcttcataca agtaatcagg
     1381 taaaaacatg gcaacggtcg ttttaacgac taaagcataa atttttcgtt gtaaatcgtc
     1441 cattttcgct aatgcagatt cggtaggtac ttgttttgtt gggataatgg cgtggtgttc
     1501 ctgtacctta ctaccgtcca cataacgctt tctaggctct gtttgaacca tttcaagatc
     1561 aagtcctaaa aaaccgctat atttgccaaa attcgctttt aaataagcaa attcgttctc
     1621 tgtaataaat ggtgtatctg ttcttggata actcaataat tttgcttcat acagtccttg
     1681 catagctttt aaacgtaaaa ttttgcgttc taagacgttt taaatatatc tgcgtatatt
     1741 tttatgtgtt ttatcttttc gtcggcaaat gcgttaaaat ttgcgaaata aaatagctca
     1801 agggcgaacg cagtgagtgc atttaccctt gatctatttt tttgagtaaa ttagcttttg
     1861 aaaccgacgg aaaggaaaca caaaactttt cagaggcaag gggtttttaa ggggcgcttt
     1921 tagccccttg aatttatttg ctttaagata tatttagttt taaaatagtt ttaacgaaaa
     1981 aaagacataa aaaaagacga gcaacgctac caacgttctc gcccggaata acaaaccaca
     2041 cttgttattc attcgatgat tagtatatca atttttgatt ttgaatacaa aacaaaatgg
     2101 acgaatggat acaggcgaaa tttattttgc gattccactc gtcctttttt cgttccaaaa
     2161 attattttag gagcgataaa aaatgaagaa aattgatgaa aaattagctg cagaaatctc
     2221 actaaaaaaa ccggccgtct ctaatagccg gttaagtaat agccggttaa gtggtcaaac
     2281 tttgggaaaa tctcaacccg cattaagttt tgatgccatg acaatcgttg gaaatttgaa
     2341 caaaactaat gctaaaaagc tatctgactt tatgagtgta gagccacaaa tacgactttg
     2401 ggatatactt caaacaaagt ttaaagctaa ggcacttcaa gaaaaagttt atatcgaata
     2461 tgacaaagta aaagcagata cttgggatag acgtaatatg cgtgttgaat ttaatcccaa
     2521 taaactcaca catgaagaaa tgatttggtt aaaacaaaat attatcgact acatggaaga
     2581 tgacggtttt acaagattag acttagcttt tgattttgaa gatgatttga gcgattacta
     2641 tgcaatgact gataaagcag ttaagaaaac tgttttttat ggtcgtaatg gcaagccaga
     2701 aacaaaatat tttggtgtcc gtgatagtga tagatttatt agaatttata ataaaaaaca
     2761 agaacgtaaa gataacgcag atgttgaagt tgtgtctgaa catttatggc gtgtagaagt
     2821 tgaattaaaa agagatatgg ttgattactg gaatgattgt tttaatgatt tacacatctt
     2881 gaaacctgcg tgggctactt tagaaaaaat taatgagcaa gctatggttt atactttgtt
     2941 gcatgaagaa agtatgtggg gaaagctaag taagaatact aagactaaat ttaaaaaatt
     3001 gattagagaa atatctccaa ttgatttaac ggaattaatg aaatcgactt taaaagcgaa
     3061 cgaaaaacaa ttgcaaaagc agattgattt ttggcaacgt gaatttaggt tttggaagta
     3121 aaataagttt tatttgataa aaattgctaa ttcagtataa ttaatattta cgaggtgaca
     3181 taacgtatga aaaaatcaga ggattattcc tcctaaatat aaaaatttaa aatttaggag
     3241 gaagttatat atgactttta atattattga attagaaaat tgggatagaa aagaatattt
     3301 tgaacactat tttaatcagc aaactactta tagcattact aaagaaattg atattacttt
     3361 gtttaaagat atgataaaaa agaaaggata tgaaatttat ccctctttaa tttatgcaat
     3421 tatggaagtt gtaaataaaa ataaagtgtt tagaacagga attaatagtg agaataaatt
     3481 aggttattgg gataagttaa atcctttgta tacagttttt aataagcaaa ctgaaaaatt
     3541 tactaacatt tggactgaat ctgataaaaa cttcatttct ttttataata attataaaaa
     3601 tgacttgctt gaatataaag ataaagaaga aatgtttcct aaaaaaccga tacctgaaaa
     3661 caccataccg atttcaatga ttccttggat tgattttagt tcatttaatt taaatattgg
     3721 taacaatagc agctttttat tgcctattat tacgataggt aaattttata gtgagaataa
     3781 taaaatttat ataccagttg ctctgcaact tcatcattct gtatgtgatg gttaccatgc
     3841 ttcactattt atgaatgaat ttcaagatat aattcatagg gtagatgatt ggatttagtt
     3901 tttagatttt gaaagtgaat ttaattttat acacgtaagt gatcataaaa tttatgaacg
     3961 tataacaacc acattttttg gttgcttgtg gttttgattt tgaatttggt tttgaactta
     4021 tggactgatt tattcagtcc attttttgtg cttgcacaaa aactagcctc gcagagcaca
     4081 cgcattaatg acttatgaaa cgtagtaaat aagtctagtg tgttatactt tacttggaag
     4141 atgcaccgaa taaaaaatat tgaagaacaa ctagcaaaag attttaaaga gttattttat
     4201 tttaagtctt tataacatga gtgaagcgaa tttttaaatt tcgatagaaa tttttacatc
     4261 aaaaagcccc ctgtcaaaat tgacgaaggg ggttttttgg cgcacgcttt tcgttagaaa
     4321 tatacaagat tgaaaatcgt gtataagtgc gccctttgtt ttgaacttag cacgttacat
     4381 caatttttta aaatgatgta taagtgcgcc cttttaaatt ttgagtgatt atattttttg
     4441 agttagaaaa agggattggg aaaatttccc aaaataattt aaaaaataag caaaaatttt
     4501 cgatagagaa tgtgctattt tttgtcaaag gtgtatacct tgactgtgct tgctgttaca
     4561 ttaagtttat ttttaagtta ttaaaaaaga aatagctttt aaagtttggc tcgctgtcgc
     4621 tttataaagc tgattgactt ttgattgcaa actacttaaa gaaaacaaac tcggactatt
     4681 cgttttcttc tctttggttt gaacatcagc aattatcccc tcttgattgc ctattttagc
     4741 ttgtttagaa gaaacaaaag ctaaaagctc ctcttgggtt ttaaaacgct gtgtggggct
     4801 tagaacgccc ttaaacgacc cttggtttac ttttatacta gcttccacct cgaaaaaagg
     4861 ttctttttta aaattctcta tggcttcctg gcgctgaaaa ataaggtata aggtgggcgt
     4921 ttgaacacgt cctagtgaaa atgtaccttg tacgcccttc tgttgtaaat ttaacgtata
     4981 caaagggctt gcgttcatgc cgatcaacca atcggcaatt tggcgtgttt gcgcttcttg
     5041 ataaaaggga tagtaattca ttccaggttg caaattttga aaaccgcttc ggattacatc
     5101 tttttctaag ctattgatcc atagtctttt aaatgtttta tcttttgaaa aggcatttgc
     5161 tttatggata atcgaccagg cgatattttc accttctctg tcgctatctg ttgcaacaat
     5221 aattgtattt gcctttttga gaagttctgc aacaatttta aactgctttc ccttatcttt
     5281 tgcaacttca aaatcgtatc gatcaggaaa aatcggcaaa gattcaagtt tccaattttg
     5341 ccacttttcg tcataatgac ctggttctgc taattccact aaatgcccaa aaccaaaggt
     5401 gataaacgtt tcatctgtaa atagtgggtc tttgatctca aaataaccgt cttttttggt
     5461 gctttgtttt aaagcacttg cgtaggctaa tgcctggctt ggtttttcag ctaaaataac
     5521 cgtactcatt aactatccct cttttcattg ttttttcttt gatcgactgt cacgttatat
     5581 cttgctcgat accttctaaa cgttcggcga ttgattccag tttgttcttc aacttcttta
     5641 tcggataaac cattcaaaaa caaatcgaaa gcatgcttta aacgtggatc attttcttta
     5701 aatttatgct gacgaccttt gaatttgcct tttttcttag caatttcgat tccttgtgcc
     5761 tgacgttcct taattttttt tcgttctgat tctgcttgat acttgtacaa ttcaatgaca
     5821 aggctattaa tcaaacgcct taaattttca tcttcaatac cattcattga gggtaaattt
     5881 aagacttcca gggttgcccc cttaatttga atttgattca tcaattctgt taattcttta
     5941 ttatttcgtc ctaatcgatc taattcagta acaataacaa tatccccttc acgaatatag
     6001 ttaagcatag cttgtaattg tgggcgttcg accgattgac cgcttaattt gtctgaaaag
     6061 accttagaaa cgccctgtaa cgcttgtaat tgccgatcta agttctgttc tttgctactg
     6121 acacgtgcat aaccaatttt agccattttc aaccaacctc taaaattctc tcggttgcaa
     6181 taaccaatca gcaatatcta ctttttcaat ttcaaattgc ttatcagaaa ttgtcttttc
     6241 gtaagcgata aaatcttgcg catattgttg ctcattaaaa atagccacca cttcgtcatt
     6301 ttctaaaact cgataaataa attttttcat tttactcctc ctattatgcc caacttaaat
     6361 gacctattca ccaagtcaat tatactgcta aaatcatatt aggacaaata ggtatactct
     6421 aatgacctat aaaagataga aaattaaaaa atcaagtgtt cgcttcgctc tcactgcccc
     6481 tcgacgtttt agtagccttt ccctcacttc gttcagtcca agccaactaa aagttttcgg
     6541 gctactctct ccttctcccc ctaataatta attaaaatct tactctgtat atttctgcta
     6601 atcattcgct aaacagcaaa gaaaaaacaa acacgtatca tagatataaa tgtaatggca
     6661 tagtgcgggt tttattttca gcctgtatca tagctaaaca aatcgagttg tgtgtccgtt
     6721 ttagggcgtt ctgctagctt gtttaaagtc tcttgaatga atgtatgctc taagtcaaaa
     6781 gaatttgtca gcgcctttat atagctttct ttttcttctt tttttacttt aatgatcgat
     6841 agcaacaatg atttaacact agcaagttga atgccaccat ttcttcctgg tttaatctta
     6901 aagaaaattt cctgattcgc cttcagtacc ttcagcaatt tatctaatgt ccgttcagga
     6961 atgcctagca cttctctaat ctcttttttg gtcgtcacta aataaggctt gtatacatcg
     7021 cttttttcgc taatataagc cattaaatct tctttccatt ctgacaaatg aacacgttga
     7081 cgttcgcttc tttttttctt gaatttaaac cacccttgac ggacaaataa atctttactg
     7141 gttaaatcac ttgataccca agctttgcaa agaatggtaa tgtattccct attagcccct
     7201 tgatagtttt ctgaataggc acttctaaca attttgatta cttctttttc ttctaagggt
     7261 tgatctaatc gattattaaa ctcaaacata ttatattcgc acgtttcgat tgaatagcct
     7321 gaactaaagt aggctaaaga gagggtaaac atgacgttat tacgccctat taaacccttt
     7381 tctcctgaaa atttcgtttc gtgcaataag agattaaacc agggttcatc tacttgtttt
     7441 ttgccttctg taccgcttaa aaccgttaga cttgaacgag taaagccctt attatctgtt
     7501 tgtttgaaag accaatcttg ccattctttg aaagaataac ggtaattagg atcaaaaaat
     7561 tctacattgt ccgttcttgg tatgcgagca ataccaaaat gattacacgt tagatcaact
     7621 ggcaaagact ttccaaaata ttctcggata ttttgcgaaa ttattttggc tgctttgaca
     7681 gatttaaatt ctgattttga agtcacatag actggcgttt ctaaaacaaa atatgcttga
     7741 taacctttat cagatttgat aatcatagta ggcataaaac ctaaatcaat agcggttgtt
     7801 aaaatatcgc ttgctgaaat agtttctttt gccgtgtgaa tatcaaaatc aataaagaag
     7861 gtattgattt gtcttaaatt gttttcagaa tgtcctttcg tgtatgaacg gttttcgtct
     7921 gcatacgttc cataacgata aacgttgggt gtccaatgtg taaatgtatc ttgattttct
     7981 tgaatcgctt cctcggaagt cagaacaaca ccacgaccgc caatcatgct tgattttgag
     8041 cgatacgcaa aaatagcccc tttgctttta cctggcttgg tagtgattga gcgaatttta
     8101 ctatttttaa atttgtactt taacaagccg tcatgaagca cagtttctac aacaaaaggg
     8161 atattcattc agctgttctc ctttcctata aatcctataa aataggttgt ttaattaact
     8221 tggtttgctt tttcattcaa ctgtttcaat attgcatgtt ttgaaaaaga tttttttcct
     8281 ttataagtca atttttttcc actaatcgaa taaattattt tgttattttc tattaactta
     8341 tatatataat cttccccctc cgaagaaaaa tacttatctg attttgtttc taagtagata
     8401 tttctctttt ctaactcttt cttaaacgtt tctagtgtat agatatttgc taattttctt
     8461 atctccaata aactattttt tatataagtt ttacattcat catgattcat acaaactcca
     8521 ccttctataa atgaatacaa aaaaagcaat caaacgattt ccgattgatt gcttaacaat
     8581 tcttaaattc agtagcttag atacttgaaa actctctgat ttccctatat aatgatagta
     8641 cggttatata ccgtcttcaa acaaagttaa ttaaataact tcttacgagg gaagagttca
     8701 tctgactaac tgataagcgt tggtttggca atcttatcgg gctatgcatt tataaaatgt
     8761 cgtcaaacat tttataaatg tgtcatggct cttttttcgt ttctattcag ttcgttgttt
     8821 cgttatatct agtataccgc ttttaaaaaa aataagcaac gatttcgtgc attattcaca
     8881 cgaagtcatt gcttttttct tcttccattt ctaaatccaa tgttacttgt tctgattctg
     8941 tttctggttc tggttctgtt ggctcatttg ggattaaatc cactactagc gttgagttag
     9001 ttaactttgc aatttgttct agtgttttta tggttggatc tgattttcct gattctattc
     9061 gtgaataatt tgatctactc atttctaatt cttgggagaa tttttctttt gatttggtac
     9121 ctctcatctt ttttaagctt tctctaaatg ctagttccaa gtttctcccc cctctttttg
     9181 tgtaataaaa ttcacgcttt atttaaatta tagcttttaa tatcttaata aacaagtgat
     9241 taatcacttg tgatttgtga ttattccaaa agtaggtaat ttcaccaacc tttttcaaaa
     9301 gtttttatcg acgattattg gactggatcg tgtttcctaa agcgattcta agcgcatgtt
     9361 taattttaaa gtgggtaatt ctctttaaaa cgtcctacaa agattcaaaa aaagcatggc
     9421 tgctagtggg ggtaccgtca ggaaaatgcg gatttacaac gttaaggaaa tttattaaag
     9481 agaccaattc ctcagcacta aaattgataa ttgggctttc tttgttacta tagtgttagg
     9541 taagcttttt actttatcac cggttttccc ctcacttcac acctacgggc gagtttcccc
     9601 acatcccgtt ttccatctaa tccaattcat tcaatatctt tatgtgtatg aaagatcaga
     9661 ttgcttgatt tagacatctt acacgtaatt tattcttaaa tgggtacggt aaacgagcaa
     9721 taatacgagc aaaagtatac ctacaaaaat aataactctg tctaattttt tttgattcat
     9781 atgcttattg cttaaaccat ataatttcag tccaagaaag cctccaacag tatttgtaat
     9841 tacatctgtt atgtctgtcg ctccaatagc gaagataaat tgaattattt caaaagtaag
     9901 acttaaaacc agtacaaaag caaacttagg taaaaatccg atttctttaa aattgacatt
     9961 caaaagcaag ccaaatggaa taaagattat aacattatct atcatctctc tgaaattccc
    10021 agtagcagta aatggagtca agttaagact tctttgatga taattaaata ctgataaaat
    10081 attgtattgt aatttgaata acactaacca gattagtgtc actaaatata aagctagcaa
    10141 tcctctagat aatatttttc ccaatataat ttcctctaat tcttttgttt aagttgtatc
    10201 attagtatag caatgtccta gttaacgtgg gttttaaatt aaaaagctaa cgttacccca
    10261 aaagtgctag tacaataatg ctgttcatta atttcgttgg tttcattccg ccatccttac
    10321 ctccttgaat tagtatgtgt tgatccggga aacactgtca caattacacc gtctatattg
    10381 tttcctgata tctcataacg aagattagtc ggcacatgaa tggtggtatt tttagtaaca
    10441 ggataataaa agatctcata tttttcccca tttacactaa cagaaatggt tttttcttct
    10501 tttaggtaat ccatatattc ctcgagaacg aaattctttt ctttcataat cgcactatgt
    10561 ggtaaaccaa catagcgaat atgccatggt tcatattgaa ttcctgttaa ctctgttttg
    10621 tcctctggat aacgtaaaat gaacccgtat ttccaagcat tttcttctat ccactttcct
    10681 tcaggggctc gttccatttt cgtcaagctt gatcctacat ctagtgataa acctgaatta
    10741 tgctcactat aacctgctgg taaggcatac tcagccccca tttcttggta aagcacactt
    10801 tgctcatcaa agtctcgata gccactatta ataataaaat gactaacgcc accctttaca
    10861 gcatcattga ccatctctga aaatttttgt gctatttctt ttgacatata aatattacta
    10921 tcaagcaacc cgtatccatt tattaattcg tcatgtttag ataaattcac gatatctgac
    10981 ttcacacttt cttggcgaac aggatattta ctattgatta atagcagatt tccttgataa
    11041 acctgttctt ctgtaattgt tttctcttgg gtattttcag aagtcccact attttctaaa
    11101 tgttctttgg gattttgatc ataattttga aattcgactt tttcctgaga aaacagtgct
    11161 tcattaacgt agtcataacc taagtatatt aagaataaca ataacaataa aaaaaacaac
    11221 ttcttcattt tcagtctcct ccttaactat atagttggaa gtatgaaata tttctagaat
    11281 cttcccctta aacggcacaa tctcgtttga gattgtgccg ttttgccccg taaattacag
    11341 tcaattattt cgccctactg gatttactat tatcaccaat gtagatgaat tttcataagt
    11401 gatacccatg ctgaatttaa cgaggctgaa ctgcctgttg acaat
//
LOCUS       DADLIO010000083        11337 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.086, whole genome shotgun sequence.
ACCESSION   DADLIO010000083 DADLIO010000000
VERSION     DADLIO010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11337
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.086"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(364..1482)
                     /locus_tag="JOX41_002407"
     CDS             complement(364..1482)
                     /locus_tag="JOX41_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450110.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            1953..3260
                     /locus_tag="JOX41_002408"
     CDS             1953..3260
                     /locus_tag="JOX41_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HAY6450111.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWGDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            3379..4578
                     /locus_tag="JOX41_002409"
     CDS             3379..4578
                     /locus_tag="JOX41_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HAY6450112.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVLLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYLAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(4605..5873)
                     /locus_tag="JOX41_002410"
     CDS             complement(4605..5873)
                     /locus_tag="JOX41_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HAY6450113.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLCLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVCRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
     gene            complement(6036..6682)
                     /locus_tag="JOX41_002411"
                     /pseudo
     CDS             complement(6036..6682)
                     /locus_tag="JOX41_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FusB/FusC family EF-G-binding protein"
     gene            complement(7090..7593)
                     /locus_tag="JOX41_002412"
     CDS             complement(7090..7593)
                     /locus_tag="JOX41_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAY6450114.1"
                     /translation="MTEKWREDEEYMSYVEDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TELSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(7716..8480)
                     /locus_tag="JOX41_002413"
     CDS             complement(7716..8480)
                     /locus_tag="JOX41_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HAY6450115.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKEEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAANKEISTFLVSDEVMDAVSDLPTPQGILAVMALTAE
                     GTPDFSGGWLLLDNVQDPGNVGTMIRTADAFDMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLTEVISLMKDKGFTVYGTELNEEAHALDKVEKSDNFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            8588..8863
                     /locus_tag="JOX41_002414"
     CDS             8588..8863
                     /locus_tag="JOX41_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HAY6450116.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            9301..10251
                     /gene="yidC"
                     /locus_tag="JOX41_002415"
     CDS             9301..10251
                     /gene="yidC"
                     /locus_tag="JOX41_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HAY6450117.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     IDVTESAKPADSKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(10430..10630)
                     /locus_tag="JOX41_002416"
     CDS             complement(10430..10630)
                     /locus_tag="JOX41_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450118.1"
                     /translation="MGGISALSFMENGVLCGRATWAKGVAPFVTEGEEKASSWMLEEG
                     KQNIKELSTLLEETATPVYVDR"
BASE COUNT         3401 a         2387 c         2002 g         3547 t
ORIGIN      
        1 taaacggtgt tccagaagta gcttcttcgg aaataagccg aaatttcaca aaaatttgag
       61 aaataatttt tgtcaatctc ttcttatttc ttgaagctga ccacttctgt cacaacctct
      121 tccttaaacg gtgttcaaaa gcttgcatct gcggtaataa gcccaccaaa caaaaaatat
      181 gaagagctat ttttgcttgc tgttcttatt acttgatgca gaacagcttt ttcacaacct
      241 ctcatacacg gtgtttaatc agctgacctt cggtattagc tcaaaaaacg gaaaaatatg
      301 tgaaactatt tttccgtttg tttctctaat actcaggtca aaacactgat ttcacaacct
      361 cttttaataa cgaagaatcg ctgtcagact cttttcatct ggcgcatctt tttgatccaa
      421 aataaacact ttcccgccat taatgatcac atcatctgct aatgcattca gcacttgacg
      481 ccgatcatat tctgtttcag gatcttcacc gaaaccatca gctaagtttg acgtagcgat
      541 aaataaatgt gacacttttc cttctttcgc agctggaacg atatcaacta actgatcgat
      601 gaatttctta tctaagagtt tattgtattc ttttgattct tgagctgcga gttcacttga
      661 cagcttcttc gccccttctt cgatatctct aaaggatagc tgcgcaggag aagcagaaat
      721 cgcaacgtct gcacaataat agggattttt agcaattttt ttgaacatcg tctgattttc
      781 tggtaatgca aataaataaa tcggccattg ttcaggattt tcgaaagaat ccttcaagta
      841 cgtatcaaca gcttggtaat agttgaccca atcgatctct acttcttcat cttttggatt
      901 tacgccatgg aaagttactc catctcgggc tccgcctcct ccattagaag agaagttcaa
      961 accgccacct gtcagttcag atcccaatgc agtaacgaca tcaaccggtg ccccttctgg
     1021 tagagatact tcttttactt gtttgttgct gacctcatac aatttcatgg agtcgcggtt
     1081 caatcccaat aaataataag aatagttgaa ctgcccattt ttgataatag ccagtaaata
     1141 aggaagatca cttacatagt attgatcgtc taccgggata ctcaaacgat ggatataggt
     1201 ctggtcagca gttataatga ccgctacact cgtagttgca ctacgccaaa acgaaggatc
     1261 tcctaacaaa ttttcaattt tttcttggaa cggggaccag tcatgttcgg aatatttttt
     1321 ctcaaaacgt ttctttgctt ctttcgcaaa atttttgaat ttgatctgat ctttttccac
     1381 atcttgatgg gcgacatgcg tattcagcat gatcgtgacg aatggtcctt tagcgccttc
     1441 tgaagtcaat tgtgtcaata attctttatc cttttttgcc ataaacgtac ccctcctaaa
     1501 aaaatcattc ctttgtttct atctaaagtc taccacaaca ctatttttcc atacaataaa
     1561 acgtatctaa aaaaataaaa cggtttctac ggttttaaat ttagctattt ttttaagtta
     1621 tcttcataat ttcctcaatt atttagcccc agtcttcaac tattcttcat gaaatgctga
     1681 taaactaaga aaaagaataa aagaggtgga tcttatgcat ttgattatga ttttcagttt
     1741 attaagtatt atcagtttat ttgctttcag cgcttcccgc ttattagatg cggaaacaca
     1801 gcctattcct gtaaaagtac gtaaaaacga ccgctaaact tccataacgc gcgttcttat
     1861 cctaaagttt tttcagaaac attgaaactc tctcccctct ctgataaaat tttaatttgt
     1921 agcgaaacaa attaattaca aggagatcgg atatgtccat aaaaaaaaca cgtctagtcc
     1981 tattattggc tagtctcatt ctttgccttg cttcttttct accagctgtt gctgtgcaag
     2041 ctgaagatac gttcaaagta aatgcaaaag cagcttttgc tgtagatgcg caaagcggta
     2101 agattcttta tgatcaagat ggagaaaaaa ccatggggat cgcttcaatc acaaaaatca
     2161 tcggtcttta catcgtcctt gatcaagtaa aagaaggaaa actgtcatgg ggtgataaag
     2221 tttcgatttc agattatgca gaaaatttga gtatcacccc agatttatcg aatgttcctt
     2281 tgcataaaga aaacacctac actgtcaaag aattattcga ctctgcaatc atccagtcag
     2341 ccaatgcttc aatggtggcc ttggcagaaa aaatctctgg cagcgaagct aaattcactg
     2401 aacgaatgaa agaacaattg aaagattggg gaatcaaaga tgcaacaatc gttaatgcat
     2461 caggattgaa caactcttat cttggcgaaa accgaccaga aggcactgga gaaaacgacg
     2521 aaaatcaaat gtctgctcaa gatgtggcca tcgttgcccg ccatttgatc ttggatttcc
     2581 cagaaatact ggatgtatca agtactacga cccaaatgtt tggcgaaaat acgcaatcac
     2641 cagtggaaat ggtcaactgg aactggatgc tcccaggatt cgttaattac aaggaaggcg
     2701 tggacggatt aaaaactggt acgactgagc ttgcaggtgc ttgtttcgtt ggtacgatca
     2761 ctaaaaacga tcaacggatc atcactgtcg tattgaatgc ggacggccat gcggaaaacc
     2821 cgagtgcccg cttcaatgaa acagaccgtt tgatggacta ctgctatgac aattggtcag
     2881 aaaaagagct cggaaaagct aacgcaagta ttcctagtct aaaaaccatt gatgtaaaag
     2941 acggaaaaga atcaacagtt cctgttgtgc ttaaaagccc tgtaaaagta tgggtacgaa
     3001 acgatatgga tactggcaaa ttaacgatca cgccaacact tgacaagaag caagtcactg
     3061 acaatgagat ccaagcacct atggataaag gtacaaaaat cggtaccgct acgatcacct
     3121 tggcagacga taaattaggc tatttagaag acaacaatgc accatcaaca gagatcatta
     3181 cggataaaac agtggaaaaa gcgaatatat tcgtgattgg ctggcgacgc gtcgcagaat
     3241 ttttcggcaa cttgttttaa ttgaacaata agaaaaacat ctttccatcg gaaagatgtt
     3301 tttttgcttt ttctagttta aataacagct tttttcatct attttcgtta tactgtataa
     3361 gaaaaaggag ttgaatttat gaatctaacc agagatctga tctttttagt tctctatctt
     3421 attggggtat tctctatcgt ttattggcga aaacagaaga aggatccttc cttgttcttt
     3481 tacggcagta cgtggacatt tacggtaatc ttaacttatt ttgtcgtgtt ggaaattttt
     3541 tattcgacct tttatttttt gattccattg ttgttcttta gtatctttgc tttttcttat
     3601 ttcacagaaa aacgaaggct actgaatggt cttttattca atgttttact catcagtttc
     3661 ggcatctact tgtttgtctt gctgtatgaa acgcaaaata tttttcttgg cggactgatc
     3721 gccttgatca cgattccatt gctacttgtc cttttatttg gtatttatgg attgattgtt
     3781 tttctttttt ggaacggggt cacagtttta cgtagagaat cgcattcatt agctaatctt
     3841 ttaacgttga tactagccat ttttcttaca ctgtttcttg tttttgactt tttcttgtta
     3901 aaatatttgc cgcaatggat aaatgctttg tttttctgcg ttcccctgat cttgatctat
     3961 ctatttatcg tattctacaa ctttttgact gtctcattct tgtatcagtt caaccggcct
     4021 cgatacaatc aagacttcat cgttgtgtta ggcgctggat tgatcaatgg agaaacagtt
     4081 tctcctcttc tagccaagcg aatcaataag gcaattgctt tttatcgggc tcaaagccgt
     4141 gctacattaa atccgcccat cttattgatg tctggcgggc aaggagcaga cgaaaaagta
     4201 ccagaggcca ttgcgatgaa acaatatgcc atggaacaag gaatccctga aagagacatt
     4261 cttgtcgaaa ccaattcgac aaccactttg gaaaacatgc tctattcaaa ggaaatcatg
     4321 gatcagcaaa tgaaagggcc ataccgcgcg atctttagtt ccaacaatta ccacattttt
     4381 agagccggtc tttatgcgcg gcaagccaaa ttgaaagcaa atggtattgg tgcaaaaaca
     4441 gctttctact acttgcctaa tgcgttttta agagaatacc tcgccatctt gatgatgaac
     4501 aaaaaaagac atatgatcat ttgcggattg cttttcgcag gctccgcatt cttatcgctg
     4561 attactttac ttttctaaaa aaacaaggtg tgacaaaaca tatgtcacac cttgtttttt
     4621 tctttcattc tcttaactat tggcaaaaag agtatccctt ttttgaccgc tacttgctga
     4681 gcagaataaa taccgctgtt gcctgaacac ataaagctga tcaagcagat cataaagaag
     4741 tatactgccg cttgtgaacc gaacaattcg atccccatca caaagcaggc aatcggtgta
     4801 tttgtcgcac cagaaaatac tccgataaag cccaatcctg caagaaaagg aacagaaaca
     4861 tggagcaaag gcgctagtgc tgcaccaagc gttgcaccaa tttcaaacaa tggtgtcact
     4921 tctccccctt gatatcccgc gcctaaagac aaaactgtga agaataactt cccaataaaa
     4981 tcatagacat gtgcctgtcc attaaatgat tcttgaagta acggaagact caatccgaga
     5041 taacgttgtg tttgcaaaat caatgctgct gccacaacta cagctccacc tatcgtattt
     5101 cgacaaacag gatgaggaat ccattgtgca tatcgcgctt ttaaaaagac gatcgaacgg
     5161 ctgaataccc aaccaatcaa accaaaagca atcccagcaa caaaaacttt gaagaacagc
     5221 aacatactcc attcaggaat cacacccatt tggtaatgta gatgagaaac accatagctt
     5281 tctgtcatga aatttgcaaa cagtgcagca aagaagctag ggaagatcgc ttctgttcgg
     5341 actttcccga ttgccaacac ttctaatcca aataatgttc cagctaaagg tgtgccaaat
     5401 acagaactaa aacccgcact gattccactg ataatcaaga tttcccgttc tgatttatcc
     5461 aatcggaaca aacgtgccgt attatctgct aacgctcccc ccatttggac tgctgttcct
     5521 tcacggccaa cagatccccc aaataaatgg gtagttatgg ttccaaacag tgtaagtgga
     5581 ataagccgca acgggatttt ttcttctcca ccatttcctt gatcgatcac taagttgttt
     5641 ccacgactag aaagtccgcc gtgatacgca tagagataag caaaaagcgc accactaact
     5701 ggtagtagac aaaggagcca aggatgtgat agtcggatat ctgtcacaac tgtcaggcta
     5761 tttaagaaaa aagcagacaa gctccccatg aatataccga gaatcgctgt gatcaccagc
     5821 cacttcagca tatacactaa aatgcgtact ggactcggta attgtttttc cataaaaaat
     5881 tcctcctcaa taaaaaaacg cctactaaag aaaggggctg tccccagact ttagtaggcg
     5941 tcattagcta tctttcgtta gcatttaaag gcgaacacca tcacctattc acttccatta
     6001 aaagatagca tatttttctg taaaaaacaa taaaattatc gttctttctt tacacgttca
     6061 gcaaattcat agaaaggagc caatttcgtt aactgttgat tacattggtc actatcatga
     6121 caaatataat tccccttttt cgtatacgtg ccatcagaac ctgctttcgt tgtagaaaga
     6181 aaaagcgaaa cattcgatgt tttctgacag attgcacaga ttcccttatt tatcgttggt
     6241 gataaagtac cgctaatccc ttttaatttt tcatcttcgt aatagaccat gaattttttc
     6301 tgcgtacctg gatcattcca gccgatgtac gtatgttctt gcaagtcgat ttcattccaa
     6361 gctggttgtt tgagtttttt cacttttcgg aataatttct cgatttgtgg tttgctaggc
     6421 tgcataaacg gctgaacgat ttgcttcagc tcctccaatg ctctttctgc ttgcgctttt
     6481 gtcagtttta cgtctaaaac tgtcgttaaa aatgtatcga ttctggcagt tcgtgatcta
     6541 atatgtctcg aatcttttca gctgctagtg cctgaactgt ttgtaccgtt tttggatcat
     6601 tgacagatga gtacgcattt aataactgtt ctacttctct tattataaaa aaatattggt
     6661 atggttttat tgtttgttcc atgattttaa agtcctttct tctaaccaaa gtgcatactt
     6721 tgtagaaaaa agtgatcttc tgcaaagtat gtgttacctg aagatcccgg actcttttaa
     6781 ataagatacg ttttgcatct tatcatcacc ccctttaatg cttattattc tatgtacatg
     6841 attcattcga taaataaaag taaaccgtat cttgaacaga tagtcaactg caaacagaaa
     6901 aaaggactgt gacaaaagtc gtgtcaaagt cccttgtttc gaatgaatgg tgttcaaaag
     6961 ctggcatctg cggtaataag ccgaaacttc acaaaaattt gagaagcaat tttcgtaaat
     7021 tccttcttat ttcttgaagc tgaccacttc tgtcacaacc tcaatatggt ctattattgg
     7081 ttttatctat taaatcgagg attctttccc aaagtaacgt tgccatctct tacgcatact
     7141 tgctgacata ggctgagcgg cttctttgac tgcgcagtat ttgtctacga atgttacgat
     7201 atatccttct ttgtacttag gcggtgcaat cgttgcgccc cacatgtgct tcaaaatgat
     7261 atctcgctca agatccgaca attcggtgat cttttctgca ttctttacag caattcttgg
     7321 atggatatac gcatgtgtgc cttcatcaaa tttcgtcgta cgccaatcat agtagaacag
     7381 atcatgcaaa agtccagcac gcgctgttgc tttagcattg ccaccccatt tttttgcgag
     7441 cagataacta tagtaagaaa cactgatgga atgctccaaa cgagtggaat gaacatgctg
     7501 tgtgtaattc gctaattttt tcactgcttc tgtttctaaa agatcttcta cataagacat
     7561 atattcttcg tcttcacgcc atttttctgt cataattatc gatctgccac ctttttgaat
     7621 ttcattttct tctgaaattg atctaagtat accaccagtg ttcggattat tctagtcgcc
     7681 ttggataaaa tagccaaagc ttaatagttc cttaatcata aagaaaaatg ataaagaaca
     7741 atccctgccg caaccccaac attcaacgat tccgcatttc ctttcatcgg gatatatacg
     7801 ttctgatcag tcaaagacaa gatttcctga cttaccccct gaccttcgtt ccccatgatt
     7861 attgcgaagt tatctgattt ttctactttg tctaatgcgt gtgcttcttc atttaattct
     7921 gtgccataca ctgtaaaccc tttgtctttc attaaagaaa tcacttctgt caaatctttt
     7981 tgcaacacag gcaaatgata attgcttccc tgcatgctgc gcagcacctt tgtactataa
     8041 atatctgccg ttcctttgcc taataaaaca ccagccatat caaatgcatc tgccgtacgg
     8101 atcatcgtcc ctacatttcc aggatcttgt acattatcta acaacagcca tcctcctgaa
     8161 aaatctggcg tgccttcagc cgttaacgcc atcactgcta agattccttg tggtgtaggt
     8221 agatccgata cagcatccat gacctcatcc gaaactagaa aagtagaaat ctctttgttt
     8281 gcggccagcc agtctcccca ttctttcatg cctcgctgtg tcacaaaaag ttcttttatt
     8341 tctgcatcag acgacgcagc ttcttcaatc agatggaacc cttccaaaag atattcttcc
     8401 ttttcttccc gatatttctt tttatgtagt ttttttaatt ctttgattct tggatttttt
     8461 gctgattgga tctctttcac attcctcacc tccccatgat tatatcatgg aataggtgct
     8521 tgagcttgtt tcatcctaaa aaaatcggta tcattaattt ataaaatagg aaagaaaggt
     8581 gacgaacatg cgcaaagtta aaatgaacgt ccaaggacgc gtccaaggcg taggatttcg
     8641 ctacatgacc aagatggtcg ctgatcaact aggcgtgact ggaacggtaa aaaacgaaga
     8701 tgacggctca gtcacgatcg aagcaatcgg caatgacgac atcatccaga aatttattga
     8761 agaagtcaag aaatctccga gcccaagtgg acgagtgcag tatgtggatg tccaagaaga
     8821 cccgatgatt gaggaacgaa agaaatttga tgtggtggga taaggttgtg aaaaagctgg
     8881 tctgcatcaa gcattaagga caggttgtga aaaatagctc tccatatttt tcaacaggct
     8941 ggacttaatg ccgtagatgc aagcttttga acaccgtcga taaggttatt cttgaggcgc
     9001 tttgcctcaa aaattaagga cagcagtgaa aaagctgatc tatcacttgc agtgagttca
     9061 tttgactccg ctttttcggg cagaaaaaaa gtttttagtt tattaaagta agaaagaaac
     9121 acttggaatc attctacttt ttcctagtat ttctttcttg attttttgtc tttttttcaa
     9181 aatttttcgc tacgtaaaag aacgaatatt tatatgaaat ttctatgaag ttgattgaat
     9241 tccatgcgct tttttagtat agttaagttt gtgtaaaaat tatagaagag gaagtattct
     9301 atgaataaat ggaaaaactg gttattggga tccggacttg tcagtatcct gctcttttta
     9361 tctggctgtg tgcggatgga ttcaaacgga aaccctgaca cttcgggaat cgtttatcga
     9421 gtactcgtcc atcctatggg ccaagcgatt acatatctag ttgaaaattt caattggtct
     9481 tatggctggg cagttattgc aatgactgtg atcgtccgta tcatcatctt gccactaggt
     9541 attagtcaat cgaaaaaaac aatgatccaa tctgaaaaaa tgcaagcgtt aaaaccacaa
     9601 gttgaagcag cccaacaaaa attgaaagct gcaacaacac gtgaagaaca aatggcagca
     9661 caagcagaaa tgcagcaagt ataccgcgaa aacggattga gtatgaccgg cggaatcggc
     9721 tgtctgcctc tattgatcca aatgccgatc ttctctgcct tgtactttac ggcacgttat
     9781 acagaaggta tccgggaatc atctttctac ggcatcgatt taggctcacc aagtatggta
     9841 cttgttgcca ttgcaggggt cgcttatctg cttcaaggat acatctcaac gatcggtatt
     9901 cctgaagaac agaaaaagac gatgcgtacg atgctgatcg tctctcctgc tatgatcgtc
     9961 ttcatgtcga tcagtgcgcc agccggtgtt acactttact gggtagtcgg tggtgtgttc
    10021 agctgtctgc aaacattcat cacaaacgtt atgatgaaac cacgtttgaa agcacaagtg
    10081 gcagaagagt tgaaacaaaa cccaccaaaa caagtcgtca ctccaagaat tgatgtgaca
    10141 gaatcagcta aaccagctga cagcaaacaa gcaaccaaac aaatcaagca acccaaaaac
    10201 agtacaaaca ataaaggccg caacgcagga aagcagcaga agcggaagta gatagtaaat
    10261 aagagtgtaa taaaaattca ttaacagttt tagcaattaa aaatatcgac caagattttt
    10321 gaaaaagaaa tctggtcgat atttttattt aagtgaatgt ttaatttgaa tcatcgattg
    10381 atcgctatct aattgcagca gcatcttttt atgaagaaac aactttttct tatctatcaa
    10441 cgtagacagg tgttgctgtt tcttctaata gtgtacttaa ttccttaata ttttgttttc
    10501 cttcttctaa catccaacta ctcgcttttt cttcgccttc ggtaacaaaa ggcgccactc
    10561 ccttcgccca tgttgctcgc ccacataaga caccattctc cataaaggac aacgcggaga
    10621 taccacccat ctaaataaca tccataaacc tttctagtag aagaatagtg atagtatcca
    10681 tccctttttc tactgggaat acaattacac gattcaaagc ttgatacaca acatttccct
    10741 tcttataaac cgctattgta accgaattgt tttgaatcac ctttttggga tagaaactgg
    10801 ctcctttccg caacttctta aatgttggtt tcttttatac tttctttgta gcaactacaa
    10861 atttcttcaa atctctaaat gtttgcataa caaccgcctt tctgactttt actcaggatg
    10921 gtatttaaaa atcagcaaaa taaggcttct ctccatcttt tttatttcct agctgcttta
    10981 aagacactct tgctgttttt taatctctat caagggggct ctgaatctat tttgatgaac
    11041 ttatcttatt aatttctcaa atgagctgtc agacacaact gtattttttc aatctcatac
    11101 cggacaacta tgccagctta aaaaaatttc ctctggcaaa acttctttat tgaaaaatga
    11161 caatgaaaaa agaccattct ttttgttgaa tgctcattgt gtaaacatat ttcctgcgac
    11221 tgctcttcga accattctca gtgcaatccc taatttatct attaaatctt cttttagttc
    11281 ctcatctttc atattcaaaa tttcctttgt atgttacaca agtttgttct ctaaata
//
LOCUS       DADLIO010000084        11269 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.087, whole genome shotgun sequence.
ACCESSION   DADLIO010000084 DADLIO010000000
VERSION     DADLIO010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11269
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.087"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            949..1422
                     /locus_tag="JOX41_002417"
     CDS             949..1422
                     /locus_tag="JOX41_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HAY6450119.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1431..1658
                     /locus_tag="JOX41_002418"
     CDS             1431..1658
                     /locus_tag="JOX41_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAY6450120.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            2294..2665
                     /locus_tag="JOX41_002419"
     CDS             2294..2665
                     /locus_tag="JOX41_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450121.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(2921..3163)
                     /locus_tag="JOX41_002420"
     CDS             complement(2921..3163)
                     /locus_tag="JOX41_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAY6450122.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(3195..4097)
                     /locus_tag="JOX41_002421"
     CDS             complement(3195..4097)
                     /locus_tag="JOX41_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAY6450123.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            complement(4110..4298)
                     /locus_tag="JOX41_002422"
     CDS             complement(4110..4298)
                     /locus_tag="JOX41_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HAY6450124.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            complement(4312..4875)
                     /gene="amaP"
                     /locus_tag="JOX41_002423"
     CDS             complement(4312..4875)
                     /gene="amaP"
                     /locus_tag="JOX41_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HAY6450125.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            complement(4913..5806)
                     /locus_tag="JOX41_002424"
     CDS             complement(4913..5806)
                     /locus_tag="JOX41_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAY6450126.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            complement(5884..6822)
                     /locus_tag="JOX41_002425"
     CDS             complement(5884..6822)
                     /locus_tag="JOX41_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAY6450127.1"
                     /translation="MRYYFVDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPD
                     DIFVGTEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLI
                     TCIDRKTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAAR
                     KTTENEELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQ
                     RQTEKMIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTG
                     GLPGKSSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            complement(6856..7206)
                     /locus_tag="JOX41_002426"
     CDS             complement(6856..7206)
                     /locus_tag="JOX41_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAY6450128.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            complement(7239..8141)
                     /locus_tag="JOX41_002427"
     CDS             complement(7239..8141)
                     /locus_tag="JOX41_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HAY6450129.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            complement(8134..8991)
                     /locus_tag="JOX41_002428"
     CDS             complement(8134..8991)
                     /locus_tag="JOX41_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HAY6450130.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            9325..10134
                     /locus_tag="JOX41_002429"
     CDS             9325..10134
                     /locus_tag="JOX41_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAY6450131.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            10174..10671
                     /locus_tag="JOX41_002430"
     CDS             10174..10671
                     /locus_tag="JOX41_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAY6450132.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(11056..11129)
                     /locus_tag="JOX41_002431"
     tRNA            complement(11056..11129)
                     /locus_tag="JOX41_002431"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11093..11095),aa:Ile,seq:cat)
BASE COUNT         3303 a         2103 c         1882 g         3981 t
ORIGIN      
        1 ttttcggaga attaaaaaat acaataaata actttagtta ctttaatgcg ttcttacttt
       61 atttttatat tatcattttt cttattcact tctttggttt atactattct tataaataaa
      121 aacgaggtat gtcctatgat gaaaagattg tactattcat tgatcataac gattggctat
      181 ttgattgtat caaatctagg aaatatggta tttggtatca gtaaagaatt cagttggact
      241 actacattat gggaatctct attctttttc atcttcgtat ttttgttaca aaattatcga
      301 aaaaaataaa catgtgccat ctatctgttg gcacatgttt taggatttat ggtacttttt
      361 attcggcaat ccattttatt tttctacttc ttcttaatac ctctaacact tttgatttat
      421 aaactaatcc aatgcatcta cttgcgctta ttaagctatt tcagctagat agtaccaccc
      481 catgcgtcaa tgcttgattt tccttttgta taacattgta taagcaataa aggacaaata
      541 agtggtgatt acaccaaacc attgaataag aaaaattctg atacgtaaat aaacatgaac
      601 ttgaaaaaat taatgaatcg gttagctact acgtagttgt cttttttctc atacagttct
      661 gttaacttac acttctcttc gctagataat aaaaaatcct ccaactgtat tgtccaatat
      721 aatcccaggc atctaaacta gcattataga agagacacac atagaatcta aaataactgg
      781 ttttaaatgt ttcttacaat caaaaaaagc tgttaaatgc actccacacc ttcatactct
      841 atcatttttt ataaacgata tatttttatt gtttttcgat aaaaaatagt tgttttacaa
      901 taattattct gctatatttt agctatcaaa gataaaagag ggataaaaat gaaatttaaa
      961 acattgctat taaaatttgt cgttttaggt ataagtgccg tatttatttt gttcggcgta
     1021 cttttttata ctcagatcgc tacaagcgaa aaaggattca attttgattg gcagaccaca
     1081 ttatttgttt ctgtcattta ctttgccctt ctcctaggga tcgttattgc ttatttctta
     1141 ttgaaactat tgaaaaaaat cgaagataac caagcttttt ccactcaaag cttaaacata
     1201 ctaaaaaaaa tcgaacgaac cattttgttt attggtttcg ccttttttgg cttacttcct
     1261 aaatttatga aagtagcgga tttagacgat gctccaggtt tgatgttggt aggaatcgct
     1321 gtcgtattca ttccttttgc agtatacaca ttaacaagcg tgctggaaaa actgcttgaa
     1381 catgcgattt tacttaagac agatcatgat ttgacagtgt gaggtgcgac atggcaatta
     1441 tcgttaattt agatgtagta ttagctcaaa aaaaaatgag tgtgactgaa ttgagtgaga
     1501 aagtgggcat tacgatggca aacatctcta ttctaaaaaa tggaaaagca aaagccatcc
     1561 gtttttccac tctcgaaaaa atctgccaag ttttggagtg tcaaccaggt gatttgttga
     1621 cctataaaaa tgactcgaat actataccag aagaataaaa taaagtagaa caaacagtaa
     1681 ataaaaaata atctgaatga tagatgtgtg agacttttag aagttattta cgtctattat
     1741 tcagattttt tatttcgatt gaataccgtt ttatctataa ataagatatg tactgactca
     1801 tacaaagggg gccttttctt ctccatgtac tatcactttt cctgatacaa ctggtttcct
     1861 gttacgttgt agttggatct gcttttagta taatacttta ttcattccac cagactgata
     1921 gcagtttgag cagtctaaat aatcatgtag tattacaggc cattctgttt cataccttga
     1981 agtgcttaaa acttcagcta atggcccatt gtgttaactc ttactccatt cttttttagt
     2041 aagctcccat atatactgta aagccttcta tatattatgt catgttgctt tttaacattt
     2101 actatgtagt tttgataaaa tgatttgaat aacagtgatg gacaattctt ttttattttt
     2161 aacattattt tgataataat gattatttat ttaaaaatac attagataac atttgttacg
     2221 acacgaaaaa gcttcacaaa caaatatcgt tattttaaaa tgagggcgaa ctcacacaat
     2281 taggaggaat agtatgccat ttattgttta cttttttctt tcattactcg tgatctatat
     2341 tccattacca acatttttcc tgctcgtcaa tcgtctagca gagcaacatg atacgattgc
     2401 tgctcttacg aaactttgtt tacttctatt tgtttgtcta gattacttta cgagctatta
     2461 ttggctaaaa cagacaagag taaaaaagag atattatttc ttccttgtct ttttcaatct
     2521 ctttgagttt ctgatccatt gctttttact tcatcagtat catacgatcc atttgtggat
     2581 catctgggtt ttcaaagtgg tcgtattatt ttgtatgttc acctttccta tctcaagaaa
     2641 atttagggag gcattgtttt attaaagaag cttctctgta tcaataaaga cacatttaag
     2701 gaaaaacttt taaaaatcta attgggaatt tgcccgcata aataagaggc tgtgacaaaa
     2761 gtcttgtcac agcctcttat tccgtataaa cagtgttcaa aagcttgcat cttcgataat
     2821 atgcccaacc aaatgaaaaa tatgagaagc tatttttgtt tggctgttct tattacttga
     2881 tgaagaacag ctttttcacg acctcttttt aaaagtcttt ttacagtttt cgagcaaaga
     2941 atgatacgat tagtactaaa atgatggcac caatcaatga tggcacgatt gccattcctg
     3001 caatacttgg tccccaagaa cctaataatg cttgaccaag tgctgatcca actaaacctg
     3061 ctacgacatt tgcaataatc cccatcgaag aacctttatt cgtgattgct cctgcaattg
     3121 ctccgataat tcctccgacg ataagtgacc aaataaatcc catgtttcgt tcctcctaat
     3181 gttttacttc cttattactg aacccgtggt tctgtatttt cttttacttt ttgtgcgccg
     3241 cttccagctg ctgattttac tttatctgtt tgattcgaag caaattcacc ggtttttttc
     3301 gctgcgtcag ttactttgtc ttgcaccgtt tcttgatctt tttcaaattc ttcttttgtt
     3361 ttgatgtcca ctacgttagc gttgacttcg atcacttcta aatgtgtcat attttttact
     3421 tctttgccga ttacttcttg catttcttca aagatttttt cgatatcttt gccatattcc
     3481 acaatgacat ccatatcaac tgctacttgt tttttaccga cttctgtttc gatcccagcc
     3541 gttacattat ctgtattcac aagttttcct gccacattag agaagaaacc accgtttgca
     3601 gataataaac cgtctacttg ttcaattgcg attccgatga ttttttgcac aactttatct
     3661 tcataattca gctcaccgcg cattgaatct tcctgttcag aatcatgctt tccttggtta
     3721 tttgtatgat cagaaccaag ttttccttgt ccgtttgtgt ggtcagaact aagtttttct
     3781 tgtgctttcg catggtcaga aggatgtttt tgctcttcca caggtttaga aggatcgatt
     3841 gcatcatgtt gttctggaac tttagattct ggagttcctg gatgatgagg tgcatgcttt
     3901 tctgcatcat gtttcttctc ttctactcct tgttgaacgt tagggactac tggatctgga
     3961 tgtgcagata ctggtgctgt tttgttcttt tcatcgttca caccatttga ttggtttggt
     4021 gtcgttgggt ctggatgtgc agacactggt ttttggttgt tcattttatt gttattattt
     4081 ttgttattgt tattcatgga tgtttcctcc taagatttaa aatagtgatc taagattttc
     4141 gtttgtttca gataaaaacc gatagcgacg ccgatcgctg ccatgatcaa gatcaataag
     4201 gtcttgaaaa agcccacggt gatccataaa acggctaata tcaatccaag taccccaaag
     4261 atgataggga gcttgtatgt cgaaaatagt tctttcattt ttggtccccc cctattctac
     4321 tcgtttgcgg tcattgcttc gtttagctgg ttcttcaaag cctgtgtatt tcaccgatac
     4381 tttcactggc tcttttgttc ccaatatgtg ttgtacttca ttttcgattt ctttcatcaa
     4441 tgttcctgtt ttaccaatga gtgctgaagt tcgtttcaac tcccctttta cattgacggc
     4501 gatcttgttt ttcgttgctt tgacatttac ttttggtgaa tggatgaatt catcttcatg
     4561 caagtgagaa cgaaccattc cttcaattgc ttttttatcc aacgtcaact ccccatcacc
     4621 atgtttcagt agaaagtttc cgattgtttt tggataaaac aggaaaacaa gtaacgtgat
     4681 aattgtcaaa atagcaaatg caacggcaag ccaaaataca tattgttgca cgtatgaatt
     4741 agtgatggaa aagaatcgaa acttctctag ctgaaaaggc aatggatagg ttgcacttaa
     4801 tagtatcgca aacaaaagca cagatagcaa aagtaatgtt ccgatcactc cgatcgtttt
     4861 tacaccttta ttcattttcg cacctcctca taggggtgaa acgatcaact tcttataagt
     4921 tgatcgcttc tccaccagtt actccgtaaa tttgggctgt aacataactt gctttattcg
     4981 atgctaagaa aacataaact ggtgctaatt ctcctggctg acctgcacgt tctagtaaac
     5041 tttgctgacc aaattcaggg atcgaatcag aaggttgtcc ttcgtctagt tgtaatggtg
     5101 tccagattgg accaggtgct acaccattta cacggattcc tttaggtgca agctgttttg
     5161 ctaaaccgat cgtaaagtta gcgattgaag cttttgttgc tgcgtaatct aataaatgtt
     5221 cgcttggatt gaatgcttga acagaagttg ttgttacgat tgctcctcct gctgggatat
     5281 gcggaacagc ttctttcact aaagcaaaca tagcgatgat gtttatcata aatgtgtctt
     5341 tgacttgctc aagtggtaac tcagcaatag actgacaaga aatttgctgt cctgcgttta
     5401 gtaccatcgt atctagcccg ccaagttcac tcacggcttt atctatgatt tctttaggtg
     5461 cttgttcgtc acgaagatca aaaggtagta agacaatctt acgtcctgca tctttcacgt
     5521 attttgctac ttcctctgca tctttttctt ctcctgggaa gaattgaaga gcgatatctg
     5581 ccccttctct agcaaatgca atcgctgctg cacgaccgat ccctgaatct ccaccagtga
     5641 ttagtacacg gcggttttct agttgattat tgccttcata ggattcttct ccacaatcag
     5701 gaacaggaat catattctgc tgtaaagctg gtgtatcctg atcttgttta ggaaatttct
     5761 ccgtatggta caagtttcgc gggtcgatta attttggttc tgtcattgct gtattcctcc
     5821 tagtttttaa attgtattgc caaaacaaat ttctttgttt gatacctgtt ttaaatagat
     5881 tctttaattt gtataatctt tccggtataa atggtaacct aaaactactg ctgctatcaa
     5941 agagccaaag actacgagta taaagcctag agcagaactt ttacccggta atcctcctgt
     6001 attcattccc caaatccctg cgaacaacgc cggaacggaa atgattaatg cagctgaatc
     6061 tagatatttc atgatatgat ttagattatt gtccatcatc ccgttgaata gatcaccaat
     6121 actctctaat aaatctcgat agatctcgat cattttttct gtttgtcgct gtctcaaatg
     6181 gacatcatag agtagctgtt catcgtctaa acgtttgatg aaagtttcag aattccataa
     6241 ttgatccatt gtttcccgtt gatctcttaa ggtatgatcg atatatacga tgtctctttc
     6301 aagatctgcc tgtttataca gttcttcatt ttccgttgtt ttacgagctg ctttatccaa
     6361 agcgtcaatt cgctttttca tctctcttag ttctttcacg taatgggtgt aaatatctaa
     6421 taatgtatac gtgatgatct tttcaaacga gtttaaatga tttccatgct ttgtcagcag
     6481 ccgatccaca aattcggttt ttctatcgat acaagtaatc aagagattat cggaaagtac
     6541 aaaagatatt ggcgttaatt ttttttcgat acgattatct gactgatcta gattaatcac
     6601 taccaaagaa aatggatgct ctagtttcgt ctcataaagg cgctccatcc gagaaacttc
     6661 ttccggatat tcggttccta cgaaaatatc atcaggaagc tcgaattctt cgattgcttg
     6721 ctcaatctct tcgggctttg cactatcaag tacgagccaa ttatattttt tttcatctgt
     6781 ttctattaca ttcttttctt catccacaaa gtagtatctc aatgtatacc tcctttttgg
     6841 actttctcga aactattagc tgaagaagca gttctttaat ttgatattat aatcgagtac
     6901 tgcgatttca ttttctaatg aaaagctgtc aagctgtttg ttgaagtcca tgttcaatcg
     6961 tttaccgaaa taattttgct ctaatttaga tgtatagatg tccaataatg gatgctcgat
     7021 tttagtcgca tattctccaa attccgaaac aaaaggaatg atttgaaaaa agctgccttt
     7081 tgcaaaagca cctttgtccc ttagaaatgg atcggaatca ttgataagcg cgagtgcgat
     7141 ttttgtattt tccccaacct tttcaattaa cgtctctact gcatttttag acattgtaat
     7201 ttccattcct actccccctc ttcagttgtt gtcttctatt atttaacaac tacatctgtt
     7261 tttggttgaa cttttgcata ttttggatat ttagggaatt tagctacaca acggaaagcc
     7321 gtcatccctg catatttttc gtaatatttc ttcgttggcc cttcaaaatc cttgctccac
     7381 ggtttcacat gtcctgaaaa atggataatg taaggattgt tgcgagtttc ttcgtattca
     7441 cgttcacctg ctgctgttgg atgttttttt gcttttgcca tgatatagcc ttgtgcattc
     7501 caacgcggat gaagtggtaa ccaacggtca tgtaagatag catttaatgc atcttggtca
     7561 tggaatcgta atttttctgg attatgttcg atgaaatcta atactttttg cgtaatattt
     7621 tcatctaacc attttttcac attgatcagc atcaaacctg agttgaaata acgcattgat
     7681 ttagctgaaa ttttcatttt ttccagtcgt tgatggaacc cagcgtcttc aacagctgct
     7741 acgattgaat caccgaagtc aagacgccat aatttagaga tatcttgtaa agcgatcatg
     7801 tcgcaatcca tatataagat acgttcaact tctgtgccgc ggaacaattc cggaatcgca
     7861 atacgataat aagctgtttc tggaatacga tcgctgatta ccacatttgt aaagaattct
     7921 ttattgattt tcaagaattc cacatctgag ttcattcgtg cgtttttcac tgagaagcgt
     7981 aaaagctgtt tactttcaaa atcgatatca tcgtcaatca catagaaccg aacaaattta
     8041 gacgggttgc aattatctaa tactgagaca aataatgcag ctaaatgtgg tacgaatttt
     8101 gtgttacaac ttgcgactac tgctatttct tttttattca ttgatctcgc ctactttcgt
     8161 tagagtactg tgtgctaatt tttttaagta taaattggta tacggatgat ctttcaacgt
     8221 attccaaggt ttatcatgtc ctgtaaagtg aacgatcgaa ggtttttcat ttccttcttt
     8281 atactgacgt tcatattttt catttggtgc tggatgacgt tcaaaaatca gcgaagtctg
     8341 catgttccat tttggatgaa gttgttccca atcttcataa agtacagcat tcaaagcatc
     8401 ttggtcgtga tagatgattc gatcgccatt ttcactgagg taatggatag ttttttctgt
     8461 aatttctttt ttattccatt gatcaatgtc aatcaccatc actcctgaat tgaagtacaa
     8521 gtcatcggaa tcgattccta atctttccaa agctttcact tggcctggat cgataatagc
     8581 gccgattgtt tttccattta acggctcatc atatagtttt acgatatcgt ctagtactaa
     8641 cacatctgaa tctaagtaaa ggactttctt ataatcctct ttagctaata agtttggtaa
     8701 agaaattctt aagtaagcgg tagttgtgat atggtcactg actaggaagt cttcgtagat
     8761 atctttttcc actgtcagga attggatact tgcattactt gaatatttat ttaccgtttc
     8821 ttccaatcct tctttactat attctgatag accatcgtca atcacataaa attttatgcg
     8881 tcttgtttta ttgcaatttt ctaatgcagt tgcgatcatc acgctcaagt aaggagcata
     8941 attttcgtct gaagcagtta ccacaggaac tacgccgtat ctcttctcca tcaaaatcac
     9001 tcctttttct aatctttttc taacctgttc tacatctaga atattcctca tttggtttta
     9061 aagcaaaata tatgctttgt tttcattgaa tattttaaaa tttttttatc acaaaacgca
     9121 tcggtaagcg ctaactattc gtttttcatg gctttttatt caaaggtatt gaccaaaaac
     9181 tactatatat agccaccttt ttcttaagaa tgttttttga aaaaattcat aatgacaaag
     9241 caagttagtt tcattttttt aaattctcat ttaatcttaa ggtaacagga aaatagatat
     9301 gtaaaaagaa agtaggaaga taaaatgaaa ctagcagcga ttgatttaga cggtaccttg
     9361 cttgatcgaa atggaaagat accagaagaa aatatccaag cacttcggaa atttgatgaa
     9421 aatggcggaa tcgtaaccgt cgctaccgga aggaacagca tttctgctaa agatattttt
     9481 tccgaattag gaatcggtgg ctatttgatt tcttccaatg gttcactgat tgctgaaatg
     9541 aaggatggaa aaatggcgaa agttctcaga cgttcaaaaa tagatagcga tacactgaga
     9601 aaagccttct tctatgctca agaagcgaaa atatccatca ttgctagccg agaaacccaa
     9661 gatgatcagc tgacattcga tgaatcaaat ctagtcaaag atgaccctta ttatgaacat
     9721 ttcaatttac agaaccattc ttttgatcaa attttaaata tgttggaaga tccttctctt
     9781 agctatctta aattagcatt aacagataag agtgaagaaa aactacagaa gctacaaaga
     9841 gatctgcaag cagatggtat ccaatcagta ttctctgatc cgcatttctt agaaatcacg
     9901 cctacaggta tcactaaagc tcattcactt gtttttctgg cggattacct tggaatcgaa
     9961 tcgagtgaca tcatggcttt tggcgatcaa gaaaacgaca ttgctatgtt gaattacagc
    10021 gggttgagta ttgcgatggg gaatgcacag cgacaagtaa aagaaattgc aaaccaagta
    10081 acactgacga atgaagaagc tggtgttgct tatattttaa aaaacttcta ttaaaaagaa
    10141 taaaatgacg atatgaatgt aggaggaaag aaaatgttag ttattattga tatgcaaaat
    10201 catattcttg atccaaacag cgaattttat attccagagt cagatcaatt ggcagaacgt
    10261 attgctcaaa gattagctaa agcacgccaa aataatgaat atattctctt cacacgggat
    10321 ataccagttg aactgaagga caaagaagaa gaacgagaag atttgcaatt gatccctctt
    10381 ctttctccac aagaaaatga acgagtgatt aaaaagtatt actttacgat tccacctgaa
    10441 actttagctg aaatccagga aactttattt gaaagcaaag aagaacaaaa agagatcgaa
    10501 gtagtcggga ttgaaacaaa cttgtgtgta ctctctaatc tgataggcct gcagagtgct
    10561 tttcctgaag cagacttttt tgttgatcca atgttagtct ccagtagaaa acacggagaa
    10621 tccgctttag agctgttgaa agatttcaac gtctctatcg tcgaatcata aaaatatcta
    10681 tcttcattta cgatatttaa cacacaataa aaaaagcacg cagaactgtt ttagtcctac
    10741 gtgctttttc tatcaaagta gattggcttt tttatgacac agagtgaaac ggcaggctca
    10801 cgacctcttt cttaaatggt gttcaatcag ctgaccctcg gtattagctt aacaaacggc
    10861 aaaatatgag gaactatttt tccgtttgtt aagctaatac tcaggtcaaa acgctgattt
    10921 cacaacctct tccttaaacg gtattcaaaa gcttgcatct gcagtaataa gaacagccaa
    10981 gtaaaaacat aagaagctgt ttttacttgg ctgttcttat tacttgatgc agggcagctt
    11041 tttcacaacc tcttatgtac cttgtaggac tcgaacctac gaccggacgg ttatgagccg
    11101 tctgctctaa ccaactgagc taaaggtaca tcataaataa aatttatttt tgttactttt
    11161 caactatagc acgaatgaca aactctcaca agtttcaaaa tataagtaaa ataatattgt
    11221 tattcttatt tcttttactt gtgtcataac tattttgtta ctttaattt
//
LOCUS       DADLIO010000085        11227 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.088, whole genome shotgun sequence.
ACCESSION   DADLIO010000085 DADLIO010000000
VERSION     DADLIO010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11227)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11227)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11227
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.088"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            189..1448
                     /gene="lysA"
                     /locus_tag="JOX41_002432"
     CDS             189..1448
                     /gene="lysA"
                     /locus_tag="JOX41_002432"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HAY6450133.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            1435..2235
                     /gene="dapF"
                     /locus_tag="JOX41_002433"
     CDS             1435..2235
                     /gene="dapF"
                     /locus_tag="JOX41_002433"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HAY6450134.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            2238..3119
                     /locus_tag="JOX41_002434"
     CDS             2238..3119
                     /locus_tag="JOX41_002434"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HAY6450135.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            3116..3832
                     /locus_tag="JOX41_002435"
     CDS             3116..3832
                     /locus_tag="JOX41_002435"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HAY6450136.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            3838..4533
                     /gene="dapD"
                     /locus_tag="JOX41_002436"
     CDS             3838..4533
                     /gene="dapD"
                     /locus_tag="JOX41_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HAY6450137.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            4549..5550
                     /locus_tag="JOX41_002437"
     CDS             4549..5550
                     /locus_tag="JOX41_002437"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HAY6450138.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            5547..6908
                     /locus_tag="JOX41_002438"
     CDS             5547..6908
                     /locus_tag="JOX41_002438"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HAY6450139.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            6868..8019
                     /locus_tag="JOX41_002439"
     CDS             6868..8019
                     /locus_tag="JOX41_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HAY6450140.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            7994..9163
                     /locus_tag="JOX41_002440"
     CDS             7994..9163
                     /locus_tag="JOX41_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAY6450141.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            9338..10717
                     /locus_tag="JOX41_002441"
     CDS             9338..10717
                     /locus_tag="JOX41_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAY6450142.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            10998..11227
                     /locus_tag="JOX41_002442"
                     /pseudo
     CDS             10998..11227
                     /locus_tag="JOX41_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3739 a         1955 c         2503 g         3030 t
ORIGIN      
        1 ataaatagct tctaatagtt cgggtatttt gtttttataa ccatttttat tcttattttt
       61 aaaaaaatat ttcgaaatat actagacaat tcagaaaatt ttgtttaata ttattccaat
      121 aaaattcaaa tctttatcaa atgaaattcc aataaaaacg gaaaaaaagt gaaaagagga
      181 atgaaaaaat gacagaattg ataattggcg gagtcacagc aagcacattg gcagaaaagt
      241 ataagacacc tctgtatgtg tatgatgaag aaaagatgag acaaacgatg ctgtcattca
      301 agcgaggctt tgtatcgaaa cgttttgata caaaagtgct ttacgcctct aaagcattcc
      361 aaacgattga gatgctgcat ttagttcgtg aatatggatt cgggctagat gttgtcagtg
      421 gtggggaaat ctataccgct ttgcaagctg attttcctag agatactatc tacttccatg
      481 gtaacaacaa gacgccagag gaactgatct atgcacttga aaatgatttg ttgcatattg
      541 ttgccgataa tttgatggaa gttgaattat tagcagaatt aagccaacgc tatttaaaaa
      601 aaatctgtat catgcttcgg ttgaatgtcg gagtagaagc acatactcat gaatatatcg
      661 tcactgcgca tattgattca aaattcggca tgagctatga aagtaaagag tgccaacaag
      721 cccttcagtt gataaaagaa agcagctatc tagagttaga aggatttcat gctcatatcg
      781 ggtcacaaat ttttgatgtt actgcttggt tagctgaaat cgacaaattg acgaattact
      841 taaccgattt tgaccaacct ctttccttga atcttggcgg agggtttggg attcgttata
      901 cacaaaatga tcagccgatc ccagtcgaag aggcactaaa aaaactgatt gaatatacgg
      961 aagaagcttt ggaaaaacga aaactgacca ttcgtcaatt actgatcgaa ccgggtagaa
     1021 gtattgttgg agaagctggt acaacactat acacgattgg tttcatcaaa aagacaccac
     1081 ataaaaaata ttactttgta gatggcggga tgacagataa tatccgtcca gctctgtatc
     1141 aggcagaata cgattgtgat ttagcagcaa aactgtcgga agaaaaaaca gagaaagtga
     1201 cgattgcagg aaaaatgtgt gaatcaggcg atgtggtaat taaagaagct tatttgccga
     1261 aagcagaatc gggtgatctt ttagctgttt attccacggg agcttatgga tactcgatga
     1321 gcagcaacta caatcgagcg acacgaccag cagttgtttt tgtcaataat ggccaatcaa
     1381 gactgattgt tcgcagacaa gcattttctg atctactaag gggggaagtt tcctatgatc
     1441 cttcataaat ataatggctg cggaaatgat tttatcttat tagattacgc agaagacaca
     1501 gattatagtc aattagccgc ttctttatgc acaaaagaaa aatatgatat agacggattg
     1561 atcgccgtaa aaatcgatcc gttggaaatg atctattaca acaaagatgg cagccgcgcg
     1621 ccgatgtgcg gaaatggcat tcgctgtttt gctcgatacg taaatgatca gaacatgatg
     1681 aatgaacagg aattcaacgt agagacatta gcaggcacaa gaaaaattac ggtgttggat
     1741 ccctcacctt tttattgcag cgtagatatg ggagtgccag atgattctcc ggaaaaaatc
     1801 aaagctaatc aaacttatcc aataaaaaac caggaaatag agatcaatgg tgaaaaagta
     1861 acgatcacta gtttattttt aggaacgatt cataccgttg tttttgttga aaatgcgcgt
     1921 gaggaagtct ggagaaaaag aggtgaactg atctgtcatc atcctttgtt caaagaaaaa
     1981 accaatgtca actttgtaga agtagtcaat gaacaagaat tgatcgtccg tacctatgaa
     2041 agaggagtag gttggacact tgcttgcggt acaggttgct gtgcctctta tgtggttgct
     2101 aaggaaactg ggaaaatttc agcagatcag gtagttgttc acttggaaca aggagacttg
     2161 atgatctctg gtgaggatgc gatacaaatg gctggcccag cagttcatga atggacaaga
     2221 atattggagg aatgaagatg ataaaaggtt cgatcgtggc gctgatcacg ccgatgaatg
     2281 aagagggatc agtagattat gctggtttgg aaaaattgat ccaattccat ttagatgaac
     2341 aaacagatgg attattagtt ttaggtacaa caggagaatc ttctacgctc acacaatctg
     2401 aggaggagca gatccttcaa ctgacagtaa agaaagtggc tggccgtgtg ccggtgattg
     2461 caggagctgg aacgaataat acgaaagaaa cgattgaaaa agcgaagcat tttgcttctt
     2521 tgggggcaga cgcacttttg gtcatcaccc cttactacaa caaaacaagt gatgcaggac
     2581 tagctgctca ttttacagca attgcagaag cctcaccgat tccgcttatt ttgtataatg
     2641 ttccttctag aacaggcatg tcgattccaa tccatgtatt agtaaattta gcagaacatc
     2701 ctaatatcat tggtttgaaa gaagcctcag gagatatggc ttatgtgatg gatgccgctc
     2761 ggttgattgg agaagaattc ttcctttaca gtggaaatga tgatttgatc ctaccagtaa
     2821 tgagtgtagg aggaagcggt gtaataagtg tatgggcgaa tatccaacct aaaatagtcc
     2881 atgaattagt aaaagatacg caggacggaa gatggcagca agcaaaagaa aagcaattaa
     2941 atgcacttga actgatccat gccttgttca gtgagaccaa tcctattcct gtcaaagcag
     3001 ccatgtcatt attagactta ccttccggac ctctacgcct gcctttagtt tctctttcaa
     3061 aagagaaaaa gaaacaatta gctcagcttt tgttaaaaga aaggacggtt gaaaaatgaa
     3121 aatcggactg attggcagtg gacagatggg aaatagagtc gaagaagttg cacaagaaag
     3181 aggagatacg gtccttcttt tacggacggc acctaaagaa gcaactacgc ttgcttttac
     3241 ggaactgcca gaactgctta ttgatttttc tcatccagat aatttagaga aaatcctttc
     3301 gtatagctta tcatatcaac ttccgttagt cattggcacg acaggttata cacaatcaca
     3361 gttccaagaa ataaaagaac atgccaaaca tgtacctgtg atgtatagtg ctaatttttc
     3421 gttcggcatc atggtgatga atcaactaat caagcaagca gctgcaatgt tgcaaggctg
     3481 gcagatcgaa ctgattgaaa aacatcatag tcgtaaaaaa gatgcaccat ctggtactgc
     3541 aaatatgctg cttcaaacaa tccaagaagt gcaaaagctg cagcccgtat acaactggca
     3601 agggaaaaaa agagaagaaa accaaattgg tgtacacagt attcgtgcag gttctttacc
     3661 tggtgaacat gatgtattgt ttgctgctac tgatgaaata tttacgatca aacatgaatc
     3721 tttttctaat cgaatctttg ctgcaggcgc agtagaagca gcggactggt tgaaagatca
     3781 gtcaccaggt tattacaaat tagaagattt attaatggac aaaggggtgt aaaaaacgtg
     3841 gaagctcaag aaatcatccg ctacattcaa acggcatcta aaaagacgcc tgtgaaagtc
     3901 tatctgaatg taaccgagcc aatcgaattt aaagaaagta aagtttttgg tgaaggaagc
     3961 agcttcgttg tttttggtga ctatgagacg attgctccgg ttttagaagc tgaatcagaa
     4021 aaaatcattg aaatcgaaat cgaaactgct gcaagataca gcgcagttcc tttgctagat
     4081 attaaaaaaa ttaatgctcg tatcgaacca ggtgctatta tcagagatca agtgtcaatc
     4141 ggcaacaatg ccgtgatcat gatgggagcg attatcaata ttggtgcagt aatcggtgaa
     4201 aacacgatga ttgatatggg tgctgtctta ggtggacgag cgacagtggg caaaaactgc
     4261 catattggtg caggagctgt cttagcaggt gtgatcgaac cagcatcggc caaaccggtt
     4321 atcgtagaag acggcgtact ggtaggtgcg aatgcagtga ttgttgaagg tgtccatatc
     4381 ggaaaagatg cagtcgtggc agcaggagca gtggttttag aagatgtggc agcagaaact
     4441 gttgtcggtg gaatacctgc acgtgtatta aaaataagtg atgatcagac aaaagaaaat
     4501 acagcattga ttgctgcgtt acgcgaatta tagaggagat ggagaaaaat gcgcgaaata
     4561 gatacctgta ttgtgggggc aaccggatta gtcggccaaa cgatgctcaa agtgttagaa
     4621 gaatatgatt ttccagtagg acgattgaaa ttattagctt caaaacgttc agccggtaaa
     4681 gtttgtgtat tcaagaaaaa gaaacacact gtacaggaat tgacagaaac ttcatttgaa
     4741 ggatatgatt tagcgctatt ttctgcaggt gcttctgtat ccaaagagtt tgcgccaatc
     4801 gcacgaagtc agggactatt tgtcatagat aattcctcag catggcggga agattcggat
     4861 attccattaa tcgttccaga ggtcaatctg gaagactata cattgaatcg gctgattgca
     4921 aatccaaatt gttcaaccat tcaagcggta cttccgctta aagctttaca agaagccttt
     4981 ggtatccagc gagtcaatta ttcgacctat caagcagttt ctggttccgg gcaaaaaggc
     5041 attgaagatc ttcatcgtac gcaaaatgac gaggaaccag ttttgtatcc ttataatatt
     5101 agccaaacgg tgattccgga aatcgatcag cctttggaaa atgggtatac aaaagaagaa
     5161 cagaaaatga taaatgagac ccgtaagatt ctgcatcagc ctgctttgcc agtatcagca
     5221 acctgcgtac gtgtgccaat cgaaaatgga catggagtct ctgtggcagt tcaactgcaa
     5281 aaagagttta cgacggaaga aattagagag tgtctcagcc agtttccagg gattcaatta
     5341 gaagatgatc tagcagcaca taaatatccg acgagcattc ttgctagagg aacagatatg
     5401 gtttatgttg ggaggatcag aaaagacact tctttagaga acggattgtt gttctatacg
     5461 actgccgata acatacgcaa aggagccgct gcgaatgccg tacagattgc tgcagcttta
     5521 atgcagaaaa tagcggaggt ggcaagatga gtaatacgct gaaagtagcg aaattcggcg
     5581 gaacatcgat gtctcatgaa gagcaattca aaaaagtccg tacaattgtt ctttcagatc
     5641 ccaatcgcca agtgatcgtt gtttctgctt taggcaaacg tacgtcagat gatgacaaag
     5701 taacagactt actttatttg atttatgctt accttcagca tcatgttgat tggacacccc
     5761 tttggaaaag gatttgtgat cgtttcattc aagtaagaga tgttcttgcc ctgcagttac
     5821 ctattgaaga tgaactagca cgcatacaga aacaactgga agacgaaaag ataactgaag
     5881 attatttagt aagtagaggt gaatatctga ctgctcaact gatggctgag tatcttggtt
     5941 accagtttat tgacgcaaaa gacctgattt tctttgacta tgatgggaaa atcgatcagg
     6001 aaaaaacagc acaggaaatc acaaaagcat ttaaaagata tccgaaaatg gttgttccag
     6061 ggttttacgg ggcgaaccct gcaggaaaag aaaaattatt gggccgtggg ggaagcgaca
     6121 ttaccggcgc gatactggcg aagatgttgc aagcggaaag ttatgagaat tggacggatg
     6181 tttcaggaat catgatggct gatccgcgaa tcatcgatca tcctaaaatc atcgaggaaa
     6241 tctcttttag agaactgaga gagatggctt atatgggggc taacgttctt catgaagcag
     6301 ctgttttccc agttcaagag gctgatatcc ccatccaaat aaaaaatacc aatgatcctt
     6361 tcgctcaagg gacaaaaata tcgaatcacg aaatagaaaa ggaaaatgga ctgacaggaa
     6421 tagctggacg caaggatttt ctttccatca ctttattcaa acgtcatatg tccgatgaaa
     6481 tcgggtttat ctggaaagca atgagcattt ttgctaaaca tgagatatca atcgaacata
     6541 ttccttcagg gatcgacaat atcggagtga tcgtctcagc agaagcgatt gccgataagt
     6601 tatttctcat cacgaaagaa ttaaaagaaa cacttggcgt ggaagaaatc gtcgtgatcg
     6661 aagacttagc tttgatctct gtcgttgggg gtccgcataa agaattgatt ggattatctg
     6721 ggaaagtgtt atcgatattg aacaaattag aaattcgcac atcgatctta tcacaaggag
     6781 cacaggagtt gaatctgatc atcggtgtac cgaataatca atatgaaaca gtagtgaagg
     6841 gtatctatga agggatggtg aatacggatg ctgaaagaat atcgaatggc actccatcaa
     6901 attcctgaaa tcgggtttca tgaattcaag acaaaaaaat atttatatga acaagtaaaa
     6961 aacagcgagg ccgttatcca tgaaatcggc gaaacaggac tactccttta ttttgataat
     7021 cagcaagaag aaacgattgc ttttcgaaca gatatcgatg cactgccagt caaagaagaa
     7081 acgaatctct cttttgcttc taagcatgaa ggttatatgc atgcatgtgg tcatgacgga
     7141 catatggcga tgcttttagg gttgactgac tttataacta aacacattga ggatcttatt
     7201 tataatgtag tactgatcta tcagccatca gaagaaattt ccggtggcgc acaaagcgtt
     7261 attcagtcag gattgttgga taaatatgaa gtacaagcaa tatttggctt tcatctatgg
     7321 cctggactag ctaagggaga agttttctct cgaccaggac ctttgatggc acaaagcagt
     7381 gaaacagaca ttatcattaa aggccagtct gcacatattg cttctagtga aaaaggaatc
     7441 gatagtctgg aggcagctgt acgatttttg aagaatgttt atgattttga ccggcaatta
     7501 ccggcagagt ggaatcatct aatgaaattt ggccaaatcc aaggtggaac gatccgaaat
     7561 gttttagctg gagaagttat tgtatccgga agtatccgtt cttacagttc agatatgcaa
     7621 aattatttga agaggggatt agaccattta gcagaacagt ttcactctac agctactatt
     7681 tcttttcgct ataatgacgg ctatccagct gtaatcaacc atagaggctt atatgcagca
     7741 ctgttagatt caaacaaact acatgaatta gatgctccag ttcttcaagc cgaagatttt
     7801 ggcatatata cgcaacaata tccatgtgta tttttctttt taggtgtcgg tgatacccct
     7861 gctttacatg atccgacgtt cgattttgat atggatgttt tagaaaatgg tgtagaatgg
     7921 tacaaaacga ttctttttac agaaaatctt cttgtaaaaa tcgatagcag ttcaaaagag
     7981 gagcgagtaa ataatgatga atttatccaa tcgatttagt cctaggcttt ctagaataga
     8041 agtatcaaaa atacgacaat tcgatcagca aatatcgtcg ataccagatg tgatcaaact
     8101 caccctggga gaaccggatt ttccaactcc tgaacatgtc aagcaagcag gaatagcagc
     8161 gattgaagaa gacttttctc actataccgg aatgagagga ttagaggaac tgcgggaagc
     8221 ggcttgtata tttcagcaac agcgttatgg attaacttat gatccgcaaa cggaagtttt
     8281 gacgacagtt ggtgcaacgg aagcgattgc ctctgcgttg ttatctgttt tggaagaagg
     8341 agacaaggtt cttattccag cgcctgctta ttcaggatat cagccattag tggaactagc
     8401 tggtgctgaa ttgatcccga tagatacttc tgacacaggg tttgtctgtc agccggaaca
     8461 atttgaacga gcatttgaac aatatggatc agctgtcaaa gcagtcattt taaactatcc
     8521 taacaatcct actgggacga cattgtctgc aaaacaattg aaagcaatcg ctgaggtttt
     8581 aaaaaaatat ccggtatttg ttataagtga tgaagtatat gctgaattga cttatagtgg
     8641 aacgcatatg tccatagcta cttatcttcc agaacaaaca atcgtgataa gcgggttatc
     8701 caagtcacat gcgatgactg gttggcgagt gggctttatt tttgctcaaa aagcccttat
     8761 tgacgaacta attaaagtcc atcaatatct ggtgactgcc gctacaacga tgtcgcaaaa
     8821 agctgcggct gaagcgctaa taaatggggt gaaagatagc gagaatatga aagagcaata
     8881 tcaaacacga agagactatc tggtccagca attggcgcct ttaggatttg aagtgaccca
     8941 gccaaacggt gcattttact tgttttgcaa actcccagct gccattcaaa ctgactcttg
     9001 gcagttttgt gtagaattag cggaacaggc aaaagttgcg tgtatcccag gaattgcatt
     9061 tggcccagaa ggagaaggtt atatccggat ttcttatgct agcagcatgg aaaaattaca
     9121 tgaggcctgc aaacggatca aagacttttt aacagaacag tgattcatag attttatcaa
     9181 aaaaacaatc gttaattttg cggtatattc tgcaaggaga cgattgtttt ttaaatttag
     9241 ttcaaatgaa cgcgtttctt ttgattcata actaatgtaa tgttaagttt aaattgttta
     9301 gaatgatttt aaaagaatat tcaaggaggt ttcatcaatg gaaaaaatca aagttgtcat
     9361 tgtaggtgca tctcatggag ggcatcaatc gatcttggaa ctattgacac gatacggtga
     9421 aaatgtagat atcacgctat ttgaagcagg agactatatt tccttcatgt catgtggtat
     9481 ggagctgtat ttagaagaca aggtaacaga tgtaaatgat gtacgtaatt tcagaccaga
     9541 aaactttccg caatccaatg ttcatatttt aaataatcac gaagtaaaaa cgatcgatgc
     9601 cgataaaaaa acagtaacgg ttactagcgc atcagataac gaaacaaaag aatatcctta
     9661 tgacaaattg attttgagtt ctggtgtcaa accaaacaat ctgccagtac caggagcaga
     9721 tctagaaaat gtctacttga tgcgtggata caattgggca accaaaatca aagaaaaatt
     9781 aaatgatccg gctattaaaa aaatcgctgt cgtaggtgcg ggttacattg ggatcgaagc
     9841 agcagaagca agccgaaaag ctgggaaaga agtcgtattg cttgatgtga tcgatagacc
     9901 tttaggcact tatttagatg ctgagatgac agatatttta gaacaacacc taaatgaaaa
     9961 cggtattgaa gttttgacaa atgcaaaaat cgaagctttt actggtaacg gaaaagttga
    10021 ggcaatcaaa acaagtgaaa aagaaatccc agcagatcta gtcattcaag ctgccggtgt
    10081 gaaggcaaat acagaatggt taaaagggat cgtcgactta gatgaacgtg gctggatcca
    10141 aacaaatgaa tacttgcaaa cgaatcttcc agatgtgtat gcagtaggag atgctacact
    10201 tgcttattct atcccagcac gcaaaaaaat gccgatcgct ttagcgactg ttgcacgtag
    10261 agaagcacgt tatgtagtaa aacatctttt tgaagaagta ccaaacaaac cgttcggcgg
    10321 agtcgtaggt tcctctgcat taagtgtctt tgactatcat tttgcagcaa gcggattgaa
    10381 tagctttaca gcagcaaaag caggagtaga tgtacgagtg tcttattatg aagatacgtt
    10441 acgaccaaaa tatgtaccag aagaacaagg aaatccaaaa gtgtccatcc aattattctc
    10501 ggatccaatg acccatcaat tgctaggagg agcagtatta tctacctatg atgttacagg
    10561 tcaaggaaat gtattggcac tagcgatcca aaacaaactg actttagaag aactagcaga
    10621 agctgacttc ttcttccagc caggctttga ccgacaatgg agcatgttga atctagccgc
    10681 tcaacaagcg ttaggagaag aaccatttgt agaataagaa aacgaaatat ttgaaaagag
    10741 gttgtgaaaa agctgccttg catcaagtaa taagaacagc caagtaaaaa cagcttctta
    10801 tgtttttaac ttggctggac ttattaccgc agatgcaagc ttttgaacac cgtttatttt
    10861 caaaaaaggg actgtgacac gatttgtgta ccgaccccca aaagttagac caaaaaatct
    10921 aacttttgga ggtcggtatt ttttatggtt aaatatactt ttgaacttaa attaaagatc
    10981 gttcatgatt atttggatgg caaaggcgat tggaccgtaa aaatccagat caagagattg
    11041 aagcggaaat gcttaaaatt cgggagaagc acaaggatta tggctgttta cggatgacca
    11101 atgaactaag aaaccgcggt ttctctatca ataaaaagaa agttcagcgc ttgatcaaga
    11161 agctaggaat aaaagtaacg gcatacacgc gtaaatcacg tcgctacaat tcttatcgag
    11221 gaaaagt
//
LOCUS       DADLIO010000086        11197 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.089, whole genome shotgun sequence.
ACCESSION   DADLIO010000086 DADLIO010000000
VERSION     DADLIO010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11197
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.089"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(13..906)
                     /locus_tag="JOX41_002443"
     CDS             complement(13..906)
                     /locus_tag="JOX41_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAY6450143.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIRPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            complement(890..1576)
                     /gene="ftsE"
                     /locus_tag="JOX41_002444"
     CDS             complement(890..1576)
                     /gene="ftsE"
                     /locus_tag="JOX41_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HAY6450144.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            complement(1681..2782)
                     /gene="prfB"
                     /locus_tag="JOX41_002445"
     CDS             complement(join(1681..2718,2720..2782))
                     /gene="prfB"
                     /locus_tag="JOX41_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078989099.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HAY6450145.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRGLFDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            complement(2908..5442)
                     /gene="secA"
                     /locus_tag="JOX41_002446"
     CDS             complement(2908..5442)
                     /gene="secA"
                     /locus_tag="JOX41_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HAY6450146.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTSQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            complement(5664..6215)
                     /gene="raiA"
                     /locus_tag="JOX41_002447"
     CDS             complement(5664..6215)
                     /gene="raiA"
                     /locus_tag="JOX41_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HAY6450147.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            complement(6343..7062)
                     /locus_tag="JOX41_002448"
     CDS             complement(6343..7062)
                     /locus_tag="JOX41_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HAY6450148.1"
                     /translation="MRCSCCSKDIFQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVKSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQVAQPKIIRTISLAR"
     gene            complement(7059..8372)
                     /locus_tag="JOX41_002449"
     CDS             complement(7059..8372)
                     /locus_tag="JOX41_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAY6450149.1"
                     /translation="MNHFWGRRLLTRDIEAIDCEEVNLPNYEKIAAVERLGNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEISKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKML"
     gene            complement(8453..8773)
                     /locus_tag="JOX41_002450"
     CDS             complement(8453..8773)
                     /locus_tag="JOX41_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAY6450150.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            complement(8881..9168)
                     /locus_tag="JOX41_002451"
     CDS             complement(8881..9168)
                     /locus_tag="JOX41_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450151.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            9295..9939
                     /locus_tag="JOX41_002452"
     CDS             9295..9939
                     /locus_tag="JOX41_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HAY6450152.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGSVSYHEQLITDHI"
     gene            complement(9998..10705)
                     /locus_tag="JOX41_002453"
     CDS             complement(9998..10705)
                     /locus_tag="JOX41_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAY6450153.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
BASE COUNT         3053 a         2430 c         1956 g         3758 t
ORIGIN      
        1 tatattgtgg tattagaatt tcaaaaaacg tctcatagaa atgatcgagc caagtgaacc
       61 aatgatcaca ccaatgccga ccattaaaag attgattttc caaacgatat tttgtggacg
      121 aatcaatgaa taatgggaac gtaataatga tggattgatc aattggaaaa accatgcata
      181 accaaatgtg atgatcaaaa tcggaagaat cgcaccgatc agaccgatcc agccaccttc
      241 aaggaaaaac ggccagcgaa tatatccatt ttttgcaccg actaaacgca tgatttgaat
      301 ttcacgctgt ctagacaaaa tcgtgatccg aatcgtgttc gaaatgagaa acatcgctac
      361 gaacagcagc aatgccgctg caactaatcc ccatgtccga actgcaccag cgatttggaa
      421 aatccgatct gaggaagctc caccgtaatc agaacgagaa acattcttca aatctgctgc
      481 ttcttctgct acttgttttg tataagaagg atcagtagca cttactacat acacatcata
      541 taacgggtta ttgtcacctt caaacaattt ccaggaatca cccatttcgt tttggatttt
      601 tttcaattcc tgttctttgc ttgaaaattc aactttttta acatgatcta agtcattcaa
      661 ttctttttct agctttttca tctcttcgtc ttttgtaccg atatctacga atacagatac
      721 atcaacgttt ccttctatat cctgagctaa tttagttgca ttcatgataa ctgccatgaa
      781 tacaccgact aaagtcaacg tgatcgttac cgcactgact gaagcaactg tcatccagcc
      841 gttacgtttc aaactcttga tactttctaa taaatggcgg aaaaaggttc taatcatcgt
      901 atccatattc cccttccgct tgatctcgaa taatgcggcc gttttcgata gcaattactc
      961 ggtgccgaat cgtatttacg atcgtactgt tatgtgtagc catcacgaca gtagttcctt
     1021 gggcattgat ccgatctaat aatttcatga tttcccatga gttttctgga tccagatttc
     1081 ctgtcggttc atccgcgata agtactttag gcgtattcac gattgcccga gcaatagaga
     1141 cacgttgctg ttccccaccg gataattcgc taggaaagac tcgaactttg tgtttcaaac
     1201 caacaaggtc cagcacttcc attactcgtt ttttgatatc tcgaggtttt ctgccgataa
     1261 cttgcatagc gtacgcaaca ttttcatata ctgtttttct tggtaataat ttatagtctt
     1321 ggaacaccac gccgatttct ctgcgtagat aaggaacttc gcggtttttg attgctatta
     1381 gatcatgacc tgcgacgttc aaagttcctt ttgaagcttt ttcttctcga tacatcaatt
     1441 tgatgaatgt agatttaccg gctccagacg gaccaaccac atagacaaac tctccttgtt
     1501 cgatgacaat cgagagattg cggatagcgg tcgtaccatt tgagtacttc ttcattacat
     1561 ccttcatttc aatcatggcg ttctctccat atctttttca gtctttagct attatagcat
     1621 ggcaatgttt caacatgctt gcaaaatctt acaattttat ttcaatttaa caatgagttc
     1681 ttattgtaga tgcattttta aatagccgtc aataaataaa tcaaggtcac cgtccataac
     1741 tgcttggaca tttcctgtct ctacgtttgt ccgatggtct tttaccatag aatagggatg
     1801 gaaaacataa gaacggatct gtgaacccca gccgatttct ttttgttctc ctcgaagtgc
     1861 agctgcttct tgttctttct tttccacttc taattgataa agcttagctt ttaacatccc
     1921 catcgcttgc tcacggtttt tcaattgtga gcgttgtgcc tgactagcta ctactgttcc
     1981 tgtaggcaag tgagtgatcc gtacagcaga ttctgtttta ttgatgtgct gaccacctgc
     2041 accacttgct cggtacgtat cgattttcaa atcatctgga ttgatttcta tatcgatcgt
     2101 ttcatcaagc tctggcatca catctaccga acaaaaagaa gtatgacgtc gtttcgctga
     2161 gtcaaaaggc gaaatccgta caaggcgatg aacacctttt tctgatttta gataaccaaa
     2221 agcgttatgt cctttaatca gcagggtcac actcttgatc cctgcttcat cacctgcttg
     2281 ataatctagt gtttctactt gatagccatg ctgctctgcc caacgtgtat acatacgtaa
     2341 aagcatgctg ccccagtctt gggactccgt tccgccagcc cctggatgca attcgacgat
     2401 cgcattgttt cgatcataag gtccgtctaa cagcatagat aattcatacg tcttcatttt
     2461 ttcatctaat gcattgatac gtgtttctgc ttcttcttgc attgctgcat caggttcttc
     2521 ttgcagcatc tccaccatca attcgatttc ttctagttct tcggcaagag aatggaattg
     2581 gtcataggtt tctttattag cgttattttc gctgatcact ttttgtgcgg cttcgctgtc
     2641 atcccaaaaa ccaggttcag ccatttttgc ttctgcttcc gcgatgtctt cttccagctg
     2701 atctaagtca aagagacctc ctgaaacttg tgaccttttc ctgcatttct gtcaggagat
     2761 ttcgaatttc ggatatttcc atgttttttc cttctttcac tatacttttt tcattatatc
     2821 tagtctaaca gaatcagcaa ataacagaaa gaaggtgaga cgaattctta aaaaaagaat
     2881 ttgtctcacc aatcctgctg tcagaaatta gtttgcattt tttccatgac agttcttata
     2941 ttttttcccg cttccacaag gacaaggatc atttcttccg accttgttca catggattgg
     3001 ctgttttttc gcgctagtat tactattttc tttggcatct ccgtcttctg agtgagaagc
     3061 tgttccttga gaaacctgtt cacgctgtac gttttgacgg atctcagctt tcataaagat
     3121 tcgagtgact tcatactcga tggcgcctac catatcttca aacatcttat agccttctgt
     3181 ttgatattcg actaatggat tgttctgtcc ataagcacgt aagccgattg actgacgtaa
     3241 ttgatccatt gcatcaatat ggtctgtcca tttagagtcc acaacacgca agatcacgac
     3301 tttttcaaat tccaacagtt gctctggacc atttagttga gccgctttgg tattaaatac
     3361 ttcttgtgct cgttcgttta gatactcttt gatctcctga gatgtttttc cttcgatatc
     3421 tgcaagagta atactatctt catggacaag agtactgccg gcaaaatcga tgatactttc
     3481 caaattccaa ttttctttct ctaattgtgt atgcgcatct actacacgac tgattgtccg
     3541 tttgaccatg ttcattagtg gcttggataa gcttttttct tccatgatta cttcttgtcg
     3601 ctgtttatag attacttcac gttgttcacg catcacatca tcgtattgta agacgttttt
     3661 acgtgtgtca tagttatttc cttctacacg tttttgtgca gattctactt gtttcgtcag
     3721 catcttgctt tggataacag catcttcctc accgatcttc atccgatcta agaaagcttt
     3781 gattcgttct gaaccgaatc gtttcatcaa atcatcttcc aatgacaagt agaattgtga
     3841 cataccaggg tctccttgac gtcctgcacg tcctcgaagc tggttatcga tacgacgaga
     3901 ttcatgtcgt tctgtcccga taactgctag accaccaagt tctcttaccc caagtcctaa
     3961 cttgatatct gttccccgac cagccatgtt ggtagcaatc gtcacagcac ctttttgacc
     4021 agcattcatg atgatctctg cttctttaaa gtgatttttc gcattcagca cttcatgagg
     4081 aatacgttct tgattcagca tatctgataa taactcagat gtttcaaccg caacagttcc
     4141 gactaacaca ggttgacctt tgcggtagcg atctttgata tcttgcacga cagcgtggaa
     4201 cttgctttgt aatgttgggt aaagtaaatc tggacgatca tcacggataa ccggacgatt
     4261 tgtcggaatc tggtatactt ggatgttata aatttctctg aattcttctt cttctgtttt
     4321 agctgtacca gtcattcccg caagtttctt gtacatacgg aaatagttct ggaaagtgat
     4381 cgtcgccatg gttttcgttt cgtcttcgat ctctacgcct tctttagctt cgattgcttg
     4441 gtgaagtcca tctgaataac ggcgtccatc catgatccga ccagtgaact ggtcaacaat
     4501 cagtactttt ccgtcttgga caacataatc gatatctaaa agcatgatat agttggctct
     4561 caatgcttga tccaagtgat gggtcaatgc agtattttca atgtcgtata agttatccaa
     4621 accgaatgtt tcttctgctt tttcgatccc tgcttcggtt aaactgattg tttttgattg
     4681 tacatcgatt ttataatctt cttcttcttt caaacgtttc acgaagttgt ctgctcttgt
     4741 atataaagct gtggattttt ctgcttgccc tgaaatgatc agcggcgttc tcgcttcatc
     4801 aatcaagatt gagtcaactt catcgacaat ggcataattc agcggacgtt gtaccatttg
     4861 atggcggtaa acgaccatat tgtctctcaa gtagtcaaat cctaattcat tattcgtact
     4921 ataagtgata tcacaattat aagcctcgcg tttttcatcc gaagattttg agttgatatt
     4981 caaccccact gttaatccta agaaattata aagttcgccc atttccgtcg agtcacgggt
     5041 tgctaaatat tcattgacgg taactacgtg taccccttcg ccagtcagag catttagata
     5101 tactggcatc gttgcggtca aggttttacc ttcaccagta cgcatttcag ggatatttcc
     5161 atcgtgaagc acgattccac ccatcaattg tacgtggtat ggatataacc ccaatacacg
     5221 ttttgctgct tctcggacga ctgcaaaagc ttccggaagt aattgatcta atgtttctcc
     5281 tttttggtat ctgcccttga attcagcagt ttttgcctgt aattgttcat cagttaatgc
     5341 tgccatttgg tcagcgtatg cttcaacttt ttttgcaatg ctatctaaac gttttagttc
     5401 tttcttatcg ttttcgataa gtgaacgaat caaattggcc atgcgttgtg taatctcctt
     5461 ttccttctgt gtattatcca gactatgtag actttacttt tcattttatc attagttata
     5521 gataattgaa atatcttaag cgtattaaag taagaacttc ataatttatt catatttcat
     5581 ctaaaagagg aggaaactca aaaaaacttg cggcagctgt cagtagctgc tgcaagtttt
     5641 cgttgttatt taagtaaggc tgatcagtct gtttcaatca gtccgtattt tccatcttta
     5701 cggcggtaaa cgatacttgt accatttgtt tctgcatctt caaaaataaa gaagttatgt
     5761 cccagcatgt tcatttgtaa gactgcttct tcactatcca ttggtttcaa tgaaaggcgt
     5821 ttcgtacgta cgatatctaa ttcagaatca ttttcgtttt cgtcctcttc attgaataaa
     5881 gcagcagcat ctgcagtatt catgcccgtt tcacgggatt tacgattaat ttttgttttg
     5941 aatttgcgga tttggcgttc caatttatca acaaccaaat cgatacttgc gtataaatct
     6001 ggagaagttt cttcggcacg taatacaaga taaggtaatg ggatcgttac ttccactttt
     6061 gctgtttttt ctgtataaac ttttaagttc acatgcgccg ttgcatcggg tgcgtcactg
     6121 aaatagcgtt ctagtttgcc tacttttttc tcaacgtagt cgcgaatcgc ttcagttact
     6181 tcgatatttt cgccgcgtac attatatcta aacataaaaa ttaccccttt cgtctaccac
     6241 aatcaagaag gagaaggacc actctttccc tcttcttaat tctattatat cgaactctag
     6301 gttatttgca aattaaatcg ctatcaaatt tccacatcta attcatctcg ccaaagaaat
     6361 ggttcggatg attttcggct gtgcgacctg caaacaatct gctgcgtgga aaagagtctg
     6421 tcctgttgta tagacatcat caataatcaa tattttttta ttttgtatct tagaaaaggt
     6481 gactgcaagt tcaaaaggtt gaggcatctc caatctttcc tttcgcgtgt tttttgcttg
     6541 agccagcaga tgcttctctc ttttgagtag catctgaaaa ggaattcttg ctgctttcaa
     6601 catctcgctt acttgattga atcctctttc tgttcgcctt ttttcagata aaggtattgg
     6661 acaatagatg tatgtcgggt attctttttt tatctgcgtc catttatatg caaaggtgcc
     6721 tgctagtcgg atatctccca taaacttgta ttgattgagc caggccttca tattttcatc
     6781 gtacacaaaa aaggcacggt gctgaaaatc ataggtcgga tatttcttct tccattcttg
     6841 acagtcactg cagtaaacgg gaatagactt tactttcttt ttcgtactct ctagattgaa
     6901 atggattggt ttttgacagc cagaacagcc tcttgtttcc aataaatgaa attgtgcgcg
     6961 acaaactgaa caagtctgag gtaatctgta tttcgaaaca ccaataatct cgctgaatgt
     7021 taaattttgg aagatatctt tactgcagca actgcacctc acagcatctt cttcccttct
     7081 tcattcattt ctttgatttc ctgacaagct tttcgaatag ctgcagtttt ttcttcatag
     7141 aaaaagtata cttgactgtt cgtataaggc cctttacgat cggctcttcc tgcgatttgt
     7201 accaaagaag atttagtaaa aaccggatga tccgctccta aaacgataac ggatattctt
     7261 tcaaatgtga ctccacgttc aaggatcatc gtggttaaca gtatatcata ttttgcttct
     7321 cgcattttct ggactttttc cgcccgctga ttgtctcttg aagaaacatc tgtgatctca
     7381 tatctcggaa gagcctcttg aagtgtggct ttcaaacgat gcatcatcgt gatacttgga
     7441 caaaataaaa ggatatggtt ttctttaatt aattgatgaa tgatccgcac caaagatttt
     7501 atcttcttct tgttcttgca tttttgtcgc caattattca tgaaaaccaa gacgggttca
     7561 ggaagcaaac gccgatgaaa gcgtaaagca agtttgtgga tgtcaaacgt ctgcttgatt
     7621 tcctttagta actttttatc aggtgtggca cttaagtaga tgaatcgtcc gtctggttta
     7681 atcgctgttt gcacagcatg agctaatcct gcatccccgt tataaggaaa cgcatcgatc
     7741 tcatcgatca ctattaaatc aaaggaccga taaaaacggt atagctgatg aatcgtacag
     7801 ataacaaaag aagtaaaggt ataagccgtt gctgtattcc catggagcaa cgtgattttt
     7861 tcttctggaa aaacataacg atagcgtaaa aacaattcat tacaaacatc gactcgcggt
     7921 gtacaaatcg ctactcttcc tccagctttt aaagtttcca ctaaaatagg ataaagcatc
     7981 tctgttttcc ctgcacctgt tacagcccaa ataagatgat gtcttttttc tgaatggcaa
     8041 agtattctct ttgagatttc cgtttgtttt tcagtaagct gtcctgtcca aaaaaagacg
     8101 acttctcgag gttttgcttc aggctgatca aacaaatata aatcttgttg agtgtcgcat
     8161 cgccctaaat atagacaatg tgtacaaaaa taaccgtaat ctgcaagctg tccatcaatg
     8221 acggacgtcc tcattccaca gcgatgacaa agaatccagt tgcccaaacg ttccactgct
     8281 gcgatcttct cataatttgg taaatttacc tcctcacagt ctattgcttc aatatctctc
     8341 gtcagaagcc ttctacccca aaaatgattc atattcttcg ccctaaaaaa atatacgaaa
     8401 aaacaagcga tctatttttt ggatcgcttg ttcgatagtt atactgttct atttattcac
     8461 ctatgagcgt gattgcttga tctaacactt tttcgccatt catcatacca taatcagcca
     8521 tattgatgac atctaaagga atgccttttg gttccagacg tttctcaaaa tcagctttca
     8581 taaagcgaac ttgtgggcct aataacaaca catccacgtc tttatttgca aggttgttat
     8641 ctgcgtcaga agcggacaca gcgaaaatat ccgagtcgat tccttttgct tcagcagctt
     8701 tttgcatttt tgttactagt aaacttgtgc tcataccagc cgaacataca agcatgattg
     8761 tttttttagc catacttttc tctccttttt aaaacaaact atgcaaacgt tttcttcgcg
     8821 tctgttactc tattatataa aaagaaagaa atttgtcaac gttttctaaa cgcggtttat
     8881 ttaatcaaat agccaactag atttcactaa tttattgaac acgacatatt ctttgtccaa
     8941 attgatgaca actacttcat agcctgcatt tatccagcca taggcacctt tttcagggtg
     9001 tttataatca tttgcccacc aatctgtact ttcccttgct gttttgggaa gtccgttact
     9061 gggaaacagc agttcgtcaa attgggtaaa ggtcaacgtt acttgagagc cgccattgtt
     9121 cttcaaataa tgcgtaattg catcgtactt tttcattcgt tcctgcatcc ccagatccac
     9181 ctgcctttgt ctttattatc gcatactaca gcaattgcgc aaccgttaca gtgttgaaac
     9241 aacctagaac tttatttata ctgaataaag aaaatgaaaa aaagaggtga caagatgatc
     9301 gagcgctatc gtacaataaa agaaaatgga caaagtgaga ttgagatcaa aaaatcacgc
     9361 tttatctgtt ctcttagacg aatagaatca gaggaccaag caaaaagttt cattcaagaa
     9421 ataaaaaaag aacattggaa agcgaaccat aactgcagcg ccttcatcat tggagaaaaa
     9481 aatgaaatcc agcgaagcag cgatgatgga gaaccaagtg gaacggcggg cgtaccgatg
     9541 ttggaagtcc tcaaaaaaaa tcaactgatc aatgtagctg cagtagtcac tcgatatttt
     9601 ggaggaacga aactcggcac aggcggatta atacgagcat acactcatgc ggtctctcaa
     9661 gcattgtctg acattggaat cgtagaaggt accttgcaac aggagatctc tgtgatgatc
     9721 acgtatccgc aactaggaaa attacagaat tatcttgaac tccaacattt ttttataaaa
     9781 gaaatccaat atactgatca agttagcgtc atctgtgctg tagatgaaaa aagtgctgac
     9841 cactttaaag aatccatcat tgagctgctg aacggacaag tccaatttga agagggttct
     9901 gtttcttatc acgagcaact gataactgat catatataaa aacaggtgat tctgattctc
     9961 ttttatttct aataaggaat cagggatcac ctgtttttta tttttccaaa taaaactcaa
    10021 aacgatttcc tacgtattgc gtacgcacat actcaaacgg cgtaccgtct tcaaaataag
    10081 aaatctggcg caaacgaaga actgcatctc ctcgttttac ctctaaatag tcagcaattt
    10141 tctcagaagc caacacagca gtaatcgttt gattcgctgg accgatcttt ttcccgcctt
    10201 tttcttctag cgtgcgatac aacgattcag taatctctgc tttgctgtag ccatcgatca
    10261 gcttttgtgg aacactggca acttcaaaac aaatagggac atcatctgcg aaacgaatac
    10321 gttccattcg caagatcgtg tcatctttac tcaagtttag tttttccatt tcacttgagc
    10381 ttggcgaagt caagaaataa gagattgtcc gactagacgg tactcgattt tgtgattcca
    10441 taatttctgt aaaacttgtt gcaccagaca ttttttcttg tactttttct cgcgcaacat
    10501 acgtacccga accgatcttt ctttctaaga ttccttcatc tgccaagttt tgaattgctt
    10561 gtctcaacgt catacggctg acattgaatt tcactgctaa ttctctttct gaaggaagac
    10621 ggtctccgac tttccatata ccctgttcga tttcattttt taattggtca tgaatctgta
    10681 tatatacagg taattgattc gacataacgt acacccgtcc tttcgtttct tctattataa
    10741 ctggtatata cctgattcac aactgaaaaa gataaaggtt tctatccatc aacagaggat
    10801 ttagacacac atcgttctcc ctactcctat tgtcagaaac aattttttag atatgttcaa
    10861 cctagaaaat aacaaaagac cctaaaatcg atgaaaatgc cgacttatgg atcttttgtt
    10921 attattagcg gtttttagcc atccattttt ttgtatgatt cgttgggcgt tttgatttta
    10981 cctggaccgc ttttccgcct tttttcggaa tattcacttc aatattgtat ttttctgatt
    11041 tgaccaaatc atataacttt tcagctgctt cgtctacttt ttctttccat ttcatgtgga
    11101 tccctccaat tcttgtagtt aacttaactc tatcttaatt cagcagaatc ttcaaggaac
    11161 aaggtagcaa agcaaaaaaa agagctctcg aactaac
//
LOCUS       DADLIO010000087        10760 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.090, whole genome shotgun sequence.
ACCESSION   DADLIO010000087 DADLIO010000000
VERSION     DADLIO010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10760
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.090"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(59..1042)
                     /locus_tag="JOX41_002454"
                     /pseudo
     CDS             complement(59..1042)
                     /locus_tag="JOX41_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311512.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
     gene            complement(1437..2279)
                     /locus_tag="JOX41_002455"
     CDS             complement(1437..2279)
                     /locus_tag="JOX41_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAY6450154.1"
                     /translation="MKGDVIVEIKVLFENSRINLNFKSGHGLSLLINYSGKKYLFDAG
                     ANKKLVYNATKMGETLNDLEAVIISHGHSDHTGGLRYLKSGNAPIYTAEGVTLPHYLK
                     ILTTFLYVGIPKNEILKMHENLHTIKTKTELAPSFHIIPLGKANSTTKNLYKKMDDKF
                     VYDDFSDELLVVIEQEDGLIVFTGCSHHGIIDMMEIALETFPTKPIKYLIGGFHMIGI
                     PYINNLGLPEQEVMKIGNKLNDSRVEKILTCHCTGSKAFNILKTQLGNKLEAIKTGQH
                     LEIS"
     gene            2604..3020
                     /locus_tag="JOX41_002456"
     CDS             2604..3020
                     /locus_tag="JOX41_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAY6450155.1"
                     /translation="MATIILASHGEFAQGLKQTATMIIGDSVPIHALSAFRDEDESIL
                     VQIKKLLATIDIEETYILTDILGGSVNNDMLTIIKEYEGLQLITGMNLPLVISIATYN
                     GKIGESELEKLIKESQQSVIDCRKLLVEQLTGGDDL"
     gene            3017..3487
                     /locus_tag="JOX41_002457"
     CDS             3017..3487
                     /locus_tag="JOX41_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAY6450156.1"
                     /translation="MIKLVRIDHRLLHGQVVFSWSKSLNINRIIIANKEAANDEFKKM
                     SLNLSKPTGIKLTIFSVEQLLEKMPKIETLNENIMLIFGNTKEIRQFCEAYPKVQEIN
                     YGGIIKKEGSKQFSNAIFLNESEQEDAKKLKALGIKQFIQQVPTSKKEDLNTML"
     gene            3501..4274
                     /locus_tag="JOX41_002458"
     CDS             3501..4274
                     /locus_tag="JOX41_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAY6450157.1"
                     /translation="MLVQSIGLGLIGVFCILDSRLLGRMNFERPLIVSTLVGLVLGDM
                     EKGLIVGASLELMSLGLVNIGAASPPDMNMASIIATAFAILSNANAEAALTIAIPISV
                     LGQILGILMRTILSNLTHVADRFIEQGKFSQARRIHILYGSGLYALMYFIPIFLAIYF
                     GTNLVSQIVDAIPEWLTNGLTVASKILPAYGFALLLQTMLTKKMVPFLLLGFLITAYS
                     GLGIIGIAAFACIVAFVMVQVQGKNSNGNQNEPDPLDDL"
     gene            4288..5100
                     /locus_tag="JOX41_002459"
     CDS             4288..5100
                     /locus_tag="JOX41_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAY6450158.1"
                     /translation="MKEKDQNAWKYRQFLWRSWAIQASWNYERQMNMGFMYGIAPILD
                     NIYKNPEDEAMKKEAYERHMMYYNCTPQTSAFVLGLTASMEEQYYEDQENFNPESISA
                     VKTSLMGPLSGVGDSFFQGTIRVLAFGLGINLAQQGSILGPILAMLISFVPSFLVTYY
                     GGKIGYNMGNKYLSKLYQEGLMDKVMYVCSIVGLMVIGSMIASMIGITTPIQMGKAFV
                     LQDVLDSIMPQFLPLGLTFFMYWLLQKKVKTGWMLAICLVGGIIFSLLGILQ"
     gene            5154..6119
                     /locus_tag="JOX41_002460"
     CDS             5154..6119
                     /locus_tag="JOX41_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAY6450159.1"
                     /translation="MNSKEIVKEIVAKKEVKSIVFVGCGASKADLYPAKYFLDQNAKQ
                     LRISHYTASEFNYATPASVDESTVVISASLGGTTPETVEANAVAKEKGATVISLTRSI
                     DSPLTKDADYVIYHRFAENYAAKLEKTGYCLELAVELLHQVEGYDHYEAMQEGFATIY
                     DLAQKSAESARKDAKKFAERFKDEKVIYVMSSGATHEVAYSTSICLMMEMQWINSGTF
                     HSGEFFHGPFEIVDKDVPFILLMNDGKTRNIDARALTFLERFDTKTEVVDALDYGLSS
                     HIAKEVLDYFNPFVITAVFRVYAEELSEAREHPLTKRRYMWKLTY"
     gene            6255..8978
                     /locus_tag="JOX41_002461"
     CDS             6255..8978
                     /locus_tag="JOX41_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAY6450160.1"
                     /translation="MQRLNDYLYQLTLLLKSTPSDNYSARSISQALQLNRSTISSYLN
                     EGVREGLFIKVKSYPVLFLHRTALEELHITLNNSEIESIESLLTISQKPALDQVIGSK
                     GSLKEAIDQIKTAVLYPGKGLPLLLIGASGSGKTFLANKIYEYAVEEKVIHTSAPFID
                     YNCAQYVSNPELLSSALFGYTKGAFTGASQEHTGLLEKADGGVLFLDEVHRLSEEGQE
                     KLFTFMDTGEFSPMGDNSIRKKADVRLVFATTENIYTTFLPTFLRRLPVIVNLPRFQQ
                     RPSFERLSLIDEFFVSESQILAKELSVSDALIHFLMNSDFEGNVGNIKNIIKYACGNA
                     YIHQKSQQTIQVKLLDMPLEYSYKFKEQLNKPRKKRADRIYYPEETRQVQLERNNQLF
                     VQFFDQLLTGFSEVIENNKDIKLFLEEMVTKVTQVMDTLIFQEDYEKEQSLYAILNYH
                     IRQSIDFMRESYGFEQDGNRVVALANYLYVKDNQVIFENSLQEKKTKDQLNEFFANVL
                     ETPYWYAKKILSLLSECLDQPVYEEDIFFITLYFYSLNVTNVKTGIKSIVLAHGYSTA
                     SSMANVANRMLNKNVFQAYDMPLDITLEKIEAKLIQFLGDYRTDSGLILLVDMGSLNQ
                     LGGLLVNHLNGPLLIIDHINTPLLLEVGQQVLNNKSITEIGAEIETSLTFKKQLLLPK
                     KKKKKAIITCCYTGIGSATQIQEILTKCLKDAVRELVIIPYDYKKLLENKNFETPFQL
                     YDVIMIVGTEDPKINQIPYIGLDRLINGGSIGEFVHYLEKELTIEVNDLQKELIFNFS
                     ISKIVENLTILDPDKVLSFVQKAIKELSKLLNFDFSNNQLFLLYLHCSCMIERIVRKE
                     SVDEQEDIEEYMQANGEIMDKIHSAFFEIEREYTIEIPDLELRLLSDIVQG"
     gene            8991..9623
                     /locus_tag="JOX41_002462"
     CDS             8991..9623
                     /locus_tag="JOX41_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAY6450161.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKALRKEVKPLLDFLKKRDIP
                     LALASSSPAVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTAALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            9828..10055
                     /locus_tag="JOX41_002463"
     CDS             9828..10055
                     /locus_tag="JOX41_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009320234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HAY6450162.1"
                     /translation="MLQQNQNTNSYQAAILTAVNLGGDTDTTAAVTGALAGILYGGEV
                     IPENWRKSLQNDQLLKTISQRFCDTVLSQRI"
     gene            10124..10390
                     /locus_tag="JOX41_002464"
     CDS             10124..10390
                     /locus_tag="JOX41_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAY6450163.1"
                     /translation="MLVQMMNGGRIMSQSTITFRIPDDEKELVLEYAKAHNSSLTELY
                     RNAVLDKIEDEIDLRTLRSAIEVSKEKKESGISQEEMEKLLNEL"
     gene            10380..10649
                     /locus_tag="JOX41_002465"
     CDS             10380..10649
                     /locus_tag="JOX41_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAY6450164.1"
                     /translation="MNYKVIYMPQAQKQLKKMDRNQAKIIVAWIRKNLENTTDPRQHG
                     KGLTGNKSGEWRYRIGNYRILANICDSEIEIQIFSIGHRSTIYKR"
BASE COUNT         3566 a         1716 c         2102 g         3376 t
ORIGIN      
        1 aataaatagt ttttctatca agtatattga actacgataa atttgttatt ttgttttgtt
       61 taatttcgtt gtacttattg gctttgactt cgatttcttt aaatactggg taatcggtgt
      121 ccggcaaagc tagcaaatct gttttttctg tgttccatag atcattgata atgacatgtt
      181 tttcgtaatg gattcgctct cgatcgtgtg acagctccac cgctaatgcc tcgttgaaac
      241 tggcgaaatc cttcataatc ggtgtagatg aaaagaagtt gtaccgtaca tagccgactt
      301 tgttttccat actacctttc tcgtttccgc tacgtggatt gcacacctgt gtctcaaaac
      361 catagtgcat agaaaatcgg aggaaaccgt cagtcagcac cgcttgttca gtctttgttt
      421 ttgtctaagt aacggccgtt gacatattat caatccgtat tttccgagga acgccacctg
      481 attggctgaa gagttctttc atgccttcca acaaacattc ttgattctcg gcggggagta
      541 caacggcgaa tcctgcatta ctaaaaggga aagtcatcac taataccttc acatctttaa
      601 acgctccatc gtgacaaact tccatcgtac caaaatcaag ttgcgcttct gctggcgggt
      661 gttcaagacg ctcaaagcct tggtcttcca gtgtttccaa gtagtgtgtc gctttccaat
      721 cttgaatgaa tacacagact gttcggtagg atcctggaaa gccatcggct tttaaagcag
      781 tagtcattgc ttcagcagtc ctacgctttt tatttggcag cttagcatct tctgaaagcc
      841 atagggaaac gatgcctccc cacttttctg tatacatcat accagtcttt ttgcgtgctt
      901 taggttgcgg cagcaaatca tcatctgcat attttttagc cgtgcgccaa tttacatcta
      961 gctcctttgc aatatgatta atggatttat catgattatt tcgtaaattt ctgatagtat
     1021 taatatcggt cattgtgagc atacctttct tacctccagt tacagtgtcg agactataac
     1081 tttagaggag tttcaggttg cccgcaatgg ctttttatct taacttaatc gatttgcgga
     1141 gttgtgtagt ttttcgttgc acttgtatgt acttttattc tgccataaac agcttaatga
     1201 atgtccactt gaaaaagtga ataaacgaaa tagatgactc gatttaataa ggaagtaaac
     1261 ccacacagaa atataggtga ttttccttga atgaccaaga tattgaaagt tagtgaaaaa
     1321 acacaaaaag gtagccctat tcacagaagg tctgcctttt gtgttatcgc cagcaaacat
     1381 tagagggggt atttcatata gcttttgtcc tctcgacagt cctatcagtt tctcttttaa
     1441 cttatctcta agtgctgtcc agttttaata gcttctagct tgtttcctaa ctgtgttttt
     1501 aatatgttga aggcttttga acctgtgcag tggcaagtaa ggattttttc tactcgtgag
     1561 tcattcaatt tatttccaat tttcattacc tcttgctcag gtagacctaa attatttata
     1621 taaggtatgc caatcatatg gaagccacca attaggtatt ttatgggttt agtcggaaat
     1681 gtttcaagag caatttccat catatcgata atgccatgat gactacagcc agtaaagaca
     1741 atcagaccgt cttcttgctc aattacgacc aataattcat ctgaaaaatc atcataaaca
     1801 aatttatcat ccatcttttt gtataaattc ttggtggtcg agtttgcttt gcctaggggg
     1861 atgatatgga agctcggagc aagttctgtt ttcgttttta ttgtatgtaa attctcatgc
     1921 attttaagga tttcattttt aggaatacca acatacagaa acgtggttaa aatctttaaa
     1981 taatggggta aagttacacc ttcagctgta taaatagggg cgtttcctga ttttaaatat
     2041 cttaacccgc cggtgtggtc agaatgaccg tgtgaaataa tcactgcctc cagatcattc
     2101 aaagtttccc ccattttagt cgcattatag actaattttt tattagcgcc agcatcgaag
     2161 agatatttct tccctgagta gttaattaag agagataacc catgtccact tttaaagttc
     2221 aaatttattc ttgagttttc aaataaaacc ttgatttcca ctataacatc tcctttcaca
     2281 tgaacgtgta ttcatatatt gtagcacatt aagttctatt ttttgttgta attaccgaaa
     2341 aaaatattaa tggacgcttt ttacgcttta tttcgtatgt ggaagaaaat ttcttaggat
     2401 gtggcggggg attggggcaa agctaaattc caattacagt gatcatttaa ttagacacct
     2461 ttaaataccc acactttcat caacactata atttagggaa agaaaagtgt tggcatgata
     2521 tagaaaaacc tttaattaac agcgtttcct aaaattggca cgcatcttgc ttatagaaaa
     2581 gcgtaaggat aggaggaatg aaaatggcaa ctataattct tgccagccat ggggaatttg
     2641 ctcaaggatt aaagcaaaca gcgacaatga ttattggaga tagtgtacca attcatgcct
     2701 tgtcagcatt tagagatgaa gatgaatcta ttttggtaca aataaaaaaa cttttagcca
     2761 caatagatat agaagaaacc tacattttaa ctgatattct aggtggtagt gtgaataatg
     2821 atatgctcac tattattaaa gagtatgagg gattgcaatt aattactgga atgaacttac
     2881 ctttagttat ttctattgca acctataatg gaaaaattgg ggaaagtgag ctagaaaagc
     2941 ttattaaaga gagtcaacaa tcagtgattg attgtagaaa attattagta gaacaactta
     3001 ctggaggaga tgacctatga ttaagttagt acgtattgac catcgtttgt tgcacggaca
     3061 ggtagtattt tcttggagta aatcattaaa tatcaatcgt attattattg ccaataaaga
     3121 ggcagcgaat gatgaattca aaaaaatgtc tttgaattta tctaaaccga ctggcattaa
     3181 attaacaatt ttttcagttg aacagttact agaaaaaatg cctaaaatcg aaacacttaa
     3241 cgaaaatatc atgcttattt ttggtaatac aaaagaaatt cgtcaatttt gtgaagccta
     3301 tcctaaagta caagaaatca actatggagg gataatcaaa aaagaaggtt ccaagcaatt
     3361 tagtaatgcc attttcttga atgaatctga gcaagaagat gccaaaaaat taaaagctct
     3421 tggcattaaa caatttattc aacaggtacc aacttctaaa aaagaagatt tgaatacaat
     3481 gttataaagg aggaatgaaa atgctcgttc agtcaattgg tttagggtta atcggtgttt
     3541 tttgtatttt agactcaagg cttttaggaa gaatgaattt tgaacgaccg ttgattgtca
     3601 gtacgcttgt tggtttggta cttggagaca tggaaaaagg attaattgtt ggagcctctt
     3661 tggaattgat gtccttagga ttagtaaata tcggagctgc ttcaccacct gatatgaata
     3721 tggcatcaat tattgctaca gcctttgcca ttttatcaaa tgcgaatgca gaagcagcat
     3781 taacgattgc cattccaatt tcagtgttag gtcaaatact aggtatctta atgcggacga
     3841 ttttgtcaaa tttgactcac gttgcggatc gctttatcga acaaggaaaa tttagccaag
     3901 caaggagaat tcatatactt tatggctcgg gattatatgc tctcatgtat tttattccta
     3961 tttttctagc aatttatttt ggaacgaatc ttgtttctca gattgttgat gcgattcctg
     4021 agtggctaac aaatggctta acggttgcaa gtaaaatttt accagcatat gggtttgcgt
     4081 tgttattaca aacgatgtta acgaaaaaaa tggtgccatt tttattactt ggatttttaa
     4141 ttactgctta ttctggattg ggaatcattg gtattgcagc cttcgcatgt attgttgcgt
     4201 ttgtcatggt tcaagttcaa ggtaaaaact caaatggtaa ccaaaatgag ccagatccat
     4261 tagatgactt ataaggaggt agattaagtg aaagagaaag atcaaaatgc atggaaatat
     4321 cggcagttct tatggcgttc atgggcaatt caagcctcat ggaactatga acgacaaatg
     4381 aacatgggtt ttatgtacgg aattgcacca attctagata acatttacaa gaatccagaa
     4441 gatgaagcaa tgaagaaaga agcttacgag cggcatatga tgtactacaa ctgtacccct
     4501 caaacaagtg catttgtgtt agggttaact gcttctatgg aggagcaata ctacgaagac
     4561 caagaaaact ttaatccgga atcaatcagt gcagtgaaga cttctctgat gggaccgcta
     4621 tctggtgttg gtgattcttt ctttcaagga acgattcggg tattagcctt tggactagga
     4681 attaatttag cccaacaagg tagtatttta ggtccaattc tagcaatgtt aatttccttt
     4741 gtaccttcct ttttagttac ttactatggt gggaaaattg gctataacat ggggaataaa
     4801 tacttgtcta aactgtatca agaaggtttg atggataaag taatgtatgt ttgctccatt
     4861 gtggggttga tggtcattgg ttcgatgatt gccagcatga tcgggattac aacaccaatt
     4921 caaatgggta aagcttttgt cttacaagat gtattagata gtattatgcc acaattttta
     4981 ccattaggat taaccttctt catgtactgg ttattgcaga aaaaggtcaa aacaggatgg
     5041 atgttggcaa tctgtttagt cggaggaatt atttttagtt tgttaggtat cttacaataa
     5101 gggaataacc aataaatttg gttgaataat ataaataagg aggaattcaa ttgatgaatt
     5161 caaaagaaat tgttaaagaa atcgtagcga aaaaagaggt aaaatcaatc gtatttgttg
     5221 gctgtggcgc ttcaaaagcg gacctttatc ctgcaaagta ttttctagac caaaatgcga
     5281 agcagttacg gattagtcat tacacagcca gcgaatttaa ctatgcaaca ccagcatctg
     5341 tagatgagtc aactgtcgtt atttcagctt ctttaggagg tacgactcca gaaacagttg
     5401 aagctaacgc agtagctaaa gaaaaaggtg ctacagttat tagtctaaca cgaagcattg
     5461 actcaccgtt aacaaaagat gcagattatg taatttatca tcgatttgca gagaactatg
     5521 ctgctaaatt agaaaaaaca ggctactgtt tagaattggc agtagaactt ttacatcaag
     5581 tagaaggtta tgaccattat gaagcaatgc aagaaggatt tgctactatc tatgatcttg
     5641 cccaaaaaag tgcagaatca gctcgtaaag atgcgaagaa atttgctgaa cgctttaaag
     5701 atgaaaaagt tatttatgta atgagtagtg gtgctacaca tgaagtagca tactcaacat
     5761 caatttgctt gatgatggaa atgcaatgga ttaattctgg taccttccat tcaggagaat
     5821 ttttccacgg accattcgaa attgtggata aagacgtacc gtttatatta ttaatgaatg
     5881 atggaaaaac tagaaatata gatgctcgag cattaacttt ccttgaacgc tttgatacga
     5941 aaacagaagt tgtagatgcc ttggattatg gcttgtcttc acatattgct aaagaagtct
     6001 tagactactt taacccattc gtgattactg cagtatttag agtttatgca gaagaattgt
     6061 cagaagcaag agaacatcca ttaactaaga gacgttatat gtggaaacta acttattaaa
     6121 aaatagatca aactaaataa ggtggcttga gaaattaagc caccttgttt tcttcaatgt
     6181 gattttatac atatggtaaa ataactagta catatggtaa aataactagt acatattgtg
     6241 aaagcaggtg gcagatgcag cgattaaatg actatcttta tcaactaaca ttgcttttga
     6301 aatctacgcc ttcagataat tattcagctc gcagtatttc gcaagctcta cagttgaata
     6361 gaagtacaat cagtagctac ttaaatgaag gtgttcgtga agggcttttc ataaaagtaa
     6421 aaagttaccc ggttttattt ttacatagaa cagctcttga agaactacat atcacactga
     6481 ataactccga aatagaatca attgaaagct tgttaacaat ttctcaaaaa cccgcattag
     6541 atcaagtaat tggctctaaa ggaagtttga aagaagcaat tgatcaaatt aaaacggcag
     6601 tcttatatcc tggaaaaggg ttgcctttat tattgatcgg cgctagtgga tcagggaaaa
     6661 cctttctagc gaataaaata tatgaatatg cagtagaaga aaaggtcatt cacacatcgg
     6721 cacctttcat agattataat tgtgcacaat atgtgagcaa tccagagtta ctatcctctg
     6781 ctttatttgg ctacacgaaa ggagcattta ccggagcaag ccaggagcat actggtttgc
     6841 tagaaaaagc cgatggagga gtattgtttt tagatgaagt gcatcgctta tctgaagaag
     6901 ggcaagagaa attatttaca tttatggata cgggtgaatt ctctcctatg ggggataata
     6961 gtattcggaa aaaagccgat gttcgattag tctttgcaac aacagaaaat atatatacga
     7021 ctttcttacc aacttttctt aggagattgc cagttattgt taatctacct agatttcaac
     7081 aacgtccgtc gtttgaacgt ctgtcattga ttgatgaatt ttttgtttct gagagccaaa
     7141 ttttagctaa ggaactatct gtttctgatg cattgattca tttcttaatg aatagtgatt
     7201 ttgaaggtaa cgtggggaat attaaaaata ttatcaagta tgcttgcgga aacgcatata
     7261 tccaccagaa gagtcagcaa acaattcaag ttaaattatt ggatatgcct ttagagtaca
     7321 gttataaatt caaggagcaa ctaaataaac ccagaaagaa aagagcagat cgaatctact
     7381 atccagaaga aacacgacaa gtgcaactag aaagaaacaa tcagcttttt gttcaatttt
     7441 ttgaccaatt acttactgga ttctctgaag tgattgaaaa taacaaggat attaaactat
     7501 ttttagaaga aatggttacc aaggtaacac aagtaatgga tacgcttatt tttcaagagg
     7561 attacgaaaa agagcagtct ttatacgcca ttctaaacta tcatattcgt caaagtattg
     7621 attttatgcg agaaagctac gggtttgaac aagatggtaa ccgggtagtc gctttggcca
     7681 actatctata tgtcaaggat aatcaagtga tttttgaaaa tagtcttcaa gaaaagaaaa
     7741 ccaaagatca gcttaacgaa ttttttgcta atgttcttga aaccccttat tggtatgcaa
     7801 aaaaaatctt aagcctttta tctgagtgtt tagatcaacc tgtgtatgaa gaggacattt
     7861 tctttattac gctatatttt tatagtttga atgtcacgaa tgttaaaaca ggtattaaga
     7921 gtattgtgct agctcatggt tattctacag ctagtagtat ggcgaatgtt gccaaccgta
     7981 tgctgaataa gaacgttttt caagcttatg atatgccttt agatattaca ttagagaaaa
     8041 ttgaagcaaa attgattcaa ttccttggag attatcgaac agattcaggc ttgattttat
     8101 tggtagatat gggttcacta aaccaactag gcggtttatt agtgaatcat ctaaatggac
     8161 cactgttaat cattgatcat atcaatacac cgttattatt ggaagtcggc caacaagtat
     8221 taaacaataa aagtatcacc gaaataggag cagaaattga aacaagtctt actttcaaaa
     8281 agcagttact acttcccaag aaaaagaaaa agaaagccat cattacttgt tgttatacag
     8341 ggattggtag tgcgacccag attcaggaga ttttaacgaa atgcttgaaa gatgcagtta
     8401 gagaattagt aattattccg tatgattaca aaaagctgtt agaaaacaag aattttgaga
     8461 ctccttttca attatacgat gtcatcatga ttgtaggtac agaagatccc aaaattaatc
     8521 agattccata tattggatta gatcgcctga ttaatggggg aagcattggc gaatttgttc
     8581 attacttgga aaaagagctg actattgaag tgaacgattt acaaaaagaa ttaattttca
     8641 atttttcaat tagtaaaatt gtcgaaaatt taaccatttt ggatccagat aaggtgctat
     8701 cttttgtaca aaaagcaatt aaagaattat cgaagttatt aaattttgat ttttctaata
     8761 atcagctgtt tttgttgtac cttcactgta gttgtatgat tgaacgaatt gtacgtaaag
     8821 aaagtgtgga tgagcaagag gacattgaag aatatatgca agcaaatgga gaaataatgg
     8881 ataaaattca tagcgctttt tttgagattg aaagggaata cacaattgaa ataccagatt
     8941 tagagttgcg attattgagc gatattgttc aaggatagga gtgaattcga atgacaatgg
     9001 gagtaatttt tgatatggat ggggtactca tagatagcga gacattttat tttgagagaa
     9061 gaatgaactt ctttcaagaa ctggagatag atccaggatc aaaccagatt gatgattatg
     9121 tggggaaaac agaagctgca atatgggaaa cattagttcc tgaggacaaa tcattaagag
     9181 aggaacttta tccgaaatat gtagattatc gaaaaacgca tccaattgat ttcgctaaag
     9241 ctttacgaaa agaagtgaaa ccgttacttg acttcctcaa gaagcgggat ataccattgg
     9301 cactggcatc ttcttctcca gctgtcgaga tagagagtat gctcattcaa tgtgaactta
     9361 ctgaatattt ttcctttgtt ataagtggtg agtcattaaa acaaagcaaa ccacatcccg
     9421 aaatatattt aaaagcgaaa cagcaattag actgtgactt ctttattgca gtagaggatt
     9481 caacgattgg tattaaatca gcaaaggcag caaatatcta tacggcggca ctaaaacaac
     9541 caatgcaaat cgatcagagt gaagcagaca tacaaattga aagtctacaa gaactggaac
     9601 aaattgtttt agaaaaaggt tagtgaatta atggaaataa ggctatatat ctgtgctagc
     9661 tattttgact aaccaaaaaa acttgctata attcaggtgt agtaaaaggt gctggtaaca
     9721 ccttttacga aaatgcttcg gcagtgataa tgggattggc tttttaagtt ttttattttg
     9781 ttcgcaatcc ctaaggtcat gtgaatgatc ctagggattg ctagaatatt ttgcaacaga
     9841 accaaaatac gaatagttat caagcagcca tattgactgc ggtcaattta ggaggggata
     9901 ctgatactac tgctgccgta actggtgctc ttgcgggtat tctttacggg ggtgaagtga
     9961 tccctgaaaa ttggagaaaa tcgcttcaaa atgaccagct tcttaaaacg atcagtcaga
    10021 gattttgcga taccgtgcta tctcaaagaa tttgaataat ggatatgatg caaatcttgt
    10081 ttgtactaac gttgtattga caaaaaggat tttatttagt acaatgttag tacaaatgat
    10141 gaacggaggt agaatcatgt ctcaatcaac cattacattt aggattcccg acgatgaaaa
    10201 agaactggta ttagaatatg caaaagcaca caattcttca ttgaccgaac tttatcgaaa
    10261 tgctgtactg gataaaatcg aagatgaaat cgatctacgg actttacgga gtgcaattga
    10321 agtttccaaa gagaaaaaag agagtggtat ttctcaagag gaaatggaga aactgctaaa
    10381 tgaattataa agtcatctac atgccgcaag cccagaagca attaaaaaaa atggacagaa
    10441 accaagctaa aataattgtc gcctggatca gaaagaattt agaaaacacg actgacccgc
    10501 gtcagcacgg aaaaggtttg actggaaata agagtgggga atggcgctat cgaattggaa
    10561 actatcgaat attggctaat atttgtgatt ctgaaattga aatccagata ttctcaattg
    10621 gacatagaag tacaatatat aaaagataac cgtttttgga acgaagtaga gtttcgaaag
    10681 tcaatgtata atcttttgaa ttttgcataa taccacaggt agaaactacc cgatactatc
    10741 ggttggtttc tgctttttta
//
LOCUS       DADLIO010000088        10635 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.091, whole genome shotgun sequence.
ACCESSION   DADLIO010000088 DADLIO010000000
VERSION     DADLIO010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10635
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.091"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(178..1026)
                     /locus_tag="JOX41_002466"
     CDS             complement(178..1026)
                     /locus_tag="JOX41_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAY6450165.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            1190..2092
                     /gene="gnd"
                     /locus_tag="JOX41_002467"
     CDS             1190..2092
                     /gene="gnd"
                     /locus_tag="JOX41_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HAY6450166.1"
                     /translation="MEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDI
                     PAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSI
                     RRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLY
                     AGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWL
                     MEIMEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEED
                     SFSAKVVSALRNGFGGHEIVEKGE"
     gene            2094..3095
                     /locus_tag="JOX41_002468"
     CDS             2094..3095
                     /locus_tag="JOX41_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HAY6450167.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            3092..3376
                     /locus_tag="JOX41_002469"
     CDS             3092..3376
                     /locus_tag="JOX41_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAY6450168.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            3409..4206
                     /locus_tag="JOX41_002470"
     CDS             3409..4206
                     /locus_tag="JOX41_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAY6450169.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            4220..5053
                     /locus_tag="JOX41_002471"
     CDS             4220..5053
                     /locus_tag="JOX41_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAY6450170.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            5071..5928
                     /locus_tag="JOX41_002472"
     CDS             5071..5928
                     /locus_tag="JOX41_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAY6450171.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            5950..6459
                     /locus_tag="JOX41_002473"
     CDS             5950..6459
                     /locus_tag="JOX41_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAY6450172.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            6496..6897
                     /locus_tag="JOX41_002474"
     CDS             6496..6897
                     /locus_tag="JOX41_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450173.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            7009..7362
                     /locus_tag="JOX41_002475"
     CDS             7009..7362
                     /locus_tag="JOX41_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450174.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            7396..7839
                     /locus_tag="JOX41_002476"
     CDS             7396..7839
                     /locus_tag="JOX41_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAY6450175.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            7856..8941
                     /gene="uxuA"
                     /locus_tag="JOX41_002477"
     CDS             7856..8941
                     /gene="uxuA"
                     /locus_tag="JOX41_002477"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAY6450176.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            8934..9647
                     /locus_tag="JOX41_002478"
     CDS             8934..9647
                     /locus_tag="JOX41_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAY6450177.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            10399..10599
                     /locus_tag="JOX41_002479"
     CDS             10399..10599
                     /locus_tag="JOX41_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAY6450178.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT         3551 a         1685 c         2309 g         3090 t
ORIGIN      
        1 ctaacaagta actcgaataa taccaataca accttctcca aagatgcgat gacatacgtt
       61 ctaacccacc gactattgat gttctgtacc acccttgcag aaccaaaaaa gccactacca
      121 aatatttggt agtggctttt tttgttttat ggatttttcg ctttttctgt tatggtgcta
      181 ttctttgatt tcagaaatag tatgtcgaac tttagcgata gaacgacgtg attctttttc
      241 gttgtaaaac atcaaaatca catatagaga gtccaaaatg cttagttgag aaatacggga
      301 agctaaagct tcagatcgga attctgtttc ttcagaaata gaaataaaaa cgacatcgcc
      361 aagtttagca agggaagaat tagcttggct agtaataacg attgtttttg ctccagtttt
      421 tcttacggtt tcagcaatat ggattgtttc ttttgattgc cctgtgtgag aaatcaaaac
      481 agcacagtct ttttccgtca ataaagaagc ttccatcaat tgaatatggt aatccgtgct
      541 gtgagaagtt gcgatagggg aacgcaaaaa tttatgataa gcgtcagttg ctacaatctc
      601 tgaaccgcca acaccgaaaa aatagacacg tttagattca ttgataatag tagccgcttt
      661 ttttagatcc ttttgttgta acaacttttt tgtgtcattt aaagttgaaa tactagactc
      721 gaacaccttt tgcgccatag tgagctcagt atctgttttc tgaatatttt cgtggataga
      781 aatagcagat agatcatttt cttggatcaa catggccatt ttaaaatctt taaatccatt
      841 ataaccaagt ttttttgtaa attgaaaaaa agtagagtca gcaatgccca gttcacttgc
      901 taaattgcta ataggactat gacttacttt gcttggattt tctaaaatat aatcggcgat
      961 agcctgttct tttgggctga agtcgttgta cattgttttg atttgtagtc ttatggagac
     1021 gctcatgaga attcctcatt ttcataataa gattatcatt ttttccgttc tcattaatgt
     1081 taaagataca aggagagtag gaaaaaatca aacaaaaaat atttttgtaa aatctattta
     1141 caaaaaaatt tttttgtata atgagggtat aagaaatgga ggcgctatca tggaaattgg
     1201 tgtaattggt ttgggaaaaa tgggattgaa tttagcttta aacttaaaag agcaccatca
     1261 caaagtacaa ggactcgaca tttcaagtac agctgttagt caggcaagag aaaatgacat
     1321 tcctgcttat caagagatct ctgaatttct agctactttt gagcagaaaa aaatcatctg
     1381 gttaatgctt cctgctggag agataaccga aaacatgtta agaaaacttt ttccaaaact
     1441 cggaccagga gacattatta ttgaaggcgg aaactcttat tataaagatt caatccgtcg
     1501 agcagaagag tttcagaaaa atgaaatcgg ttacttggat tgtgggactt ctggaggaat
     1561 cgaaggagca cgacatcaag cctgcttaat gattggagga gataaagaaa cttttctatc
     1621 cgtggaacaa ttattcaaag atgtagcaat tgaaagagga tatctgtatg ctggtgcatc
     1681 cggaagcgga cacttcttga aaatgatcca taatggaatc gaatatggaa tgatgcaagc
     1741 aatcggtgaa ggattccaac ttgtacaaaa aagtgagtat gcttttgact tggaacaagt
     1801 cgcacgtgtt tggaatcatg gttcggtgat tcgcggctgg ctgatggaaa tcatggaaga
     1861 tcagttaaac gaacatccca atttaagtaa ttatcgggga atcgtttctg catcaggtga
     1921 agcaaaatgg acggttgaaa cagcgctaga aatggctgtt ccagttccag taattgcaac
     1981 tagtttgttc atgaggaatc tttcacagga agaagatagt ttttcagcaa aagtagtttc
     2041 agcactaaga aatgggtttg gcggacatga aatagttgaa aagggtgagt aaaatgccag
     2101 attatcatat agcaatcgtt aattccagca gtttcggaag agtctttcca caccacttgg
     2161 aaagattaaa gtcagttgga gacgttcatt tctttactgt tgatcaagag attccaggaa
     2221 aagaactagc ggagttactt aaaggattca atatcattat tgcaagtgtt acgccatttt
     2281 ttcgacgaga tttttttgaa aacaaagatg aactgctatt gatttcccga catggtattg
     2341 gttacaacaa tattgattta aaagcagcaa aagaacacca gacaatcgta tctatcatac
     2401 ctgctttagt tgaacgaaat gctgtagcag aaaataatat aactaatttg ttgtccatgc
     2461 ttcgacgcac gacacaagca caagcaagag tcaaggacga tcgatgggaa gatcgggcgg
     2521 agttcgtcgg taggacgctg tttaacaaaa cagttggtgt gattggtgca ggaaataccg
     2581 gaagcggagt aatcgaaatt ttgcgtaacg gttttcgctg tgatgttcta gcttatgatc
     2641 cttacaaatc agatttatac atcgaaagct ttggtgcaaa aaaagtagaa cttcaagaat
     2701 tactggaaca atcagatatc atttgtttat gtgcgaattt gacagaagag aactatcaca
     2761 tgatttctga taaagaagtc gatcagatga aagaaaatgt ttatctatct aatagtgcaa
     2821 gaggcgctct agttgatgaa gaagcgatga ttaatggtct gaaaagcgga aagatcgcag
     2881 gatatgccac agatgtttta gaagaagaac cgggacgtca agatcatccg tatttagcgt
     2941 ttgaacaagt agtgattacg ccacatatat cggcctacac aagggaatgt ttagaagcaa
     3001 tgggtgaaaa atgtgtcaga gatgtcgaac agatcagtca gcaccttctt cctgaacgtt
     3061 ctgtccagac aaagagcaac tatataaaag gatgatgaag aaaatggtga acggtttaaa
     3121 agtgaaaaca ggccctcaat tttatttata tgaagaaggt ggtatttcaa aagtttctga
     3181 tctcttgaaa tcatacggcg cgaaaagagt actggtcacc cacggaacgg tatcatggga
     3241 aaaggcgcta cctaaattag tatttttgaa tgacgaaacg attcaatttt tttatcatcg
     3301 ttattctgga gaatgtagtt atgctgaagc cagacgaata gctacaatca tcaaaaaaat
     3361 gaaatcgatt tcgtagttgg cgttggcgga ggaaaactga ccgatctagt gggttatagt
     3421 gccaatcttg caagaatcga tttcggagtc atccctactt tagctagtaa ttgtgctcca
     3481 tggacacctc ttgctgtcat gtataaggag aatggacaag cagaagggaa aacagaacac
     3541 ttttacagac aagctgcttt ttttataaca gatccccaat tagtgattga ttcccctgtt
     3601 ccatatttca ttgccgggtt agcagataca ctagcaaaat ggtatgaatc tgagctcatc
     3661 ttagaacaag attttttgca agatgaatca tttttgaagc tagcacaaga tactgcgaag
     3721 atctgcaaag aagagatttt gaatcattct gctaaagcaa tccaagatat ggcacaaaga
     3781 aaactgacat cggagttcaa acagctttca gagattatct ttgctgttgc tggtttagtt
     3841 ggaggattag gagataaata cgcaagaaat gtggcagcac atgctatgca tgacgctatc
     3901 agtaaatata ttccggaaag ccatcgtttt ctacatggag aaaaagtagc gtatgggatt
     3961 ttctatcaac tggcactaga aggtcgctgg gaaaaaatag acgagttata tcctttgtat
     4021 cgggaattag aactgccggt ttctctagaa caaatgggat tatttccgaa agataaacag
     4081 ataatagata aaatggctga atttattgat tcgaaagaga aagtgcattt gattcctata
     4141 gaggtaacac agaaatcact gatacagtca atgatggaac tggaaggtta tatcagaaag
     4201 atctgaagga ggaggacaca tggaaacatt aagtgtagta caaagtttgt tgattgcttt
     4261 atgggtagcc gcggttatgt cccgctggtt aggtggagga gccacgttga ccttacgttt
     4321 ttctcctttg atgactggat tagtcgtcgg gttgatcatg ggggaagttg cacaagcgat
     4381 gattgttaca gccgctttgc aaatgattta tatgggggtt ttttctccag gaggatcaat
     4441 gccagctgaa ccatctattg cagcagctat cgcagtacca gtcgcattat taggggatct
     4501 gtcgccagaa gcagcgattg ccgttgcggt gccagtcgga ttgctcggaa gttacttgta
     4561 tcagtttcgt tttttcatca atactttttt aggtaaatat acagacaaag ctgtagaaga
     4621 tttgaataca aaagctatgg cccgatcaat tattctttat ccaacggttg cctcattttt
     4681 attattcgtt ccgcttgttt tcattgcttt atatttaggg gcgccattga tcgctgatgt
     4741 aatcaaagct ttagagggaa cagtcgttat ccacattctt gaagtagtag gtggagggtt
     4801 agcggcaatc ggtatcgcga caactgtata cgttatcggt cgaaaagatt atctggtctt
     4861 tttcttcctt gcttatttta tgagtgttgt tttgaaatct ttagatatta cgatggttac
     4921 ttatgccatt tttgggatta ttatcgcttt gatctttgtc cagtcgcaaa aagggaaaca
     4981 agtacagcct gccacaagca ataacaattc agcatctttt gatgacgaag atgactatga
     5041 tgacggattt taatttagga ggaatgggaa atggctgaaa taatggataa tcaaacaggt
     5101 gctcctgaag aaatcacgaa aaaagatgta acaaaagcct atctgagatg gcattttgca
     5161 aacgaaattc ctcactcttt tgaacgttac ttggcgccat cactactata cggaatgatg
     5221 ccaatcttga aaaaacttta taaagatgaa gactctttaa aagcagcata taaacggcag
     5281 ttactgttct tcaacactca attaagctgg ggtggcggtg tgattactgg cctaatgtct
     5341 tctatggaac agcaaagagc agaagaagag tatgaagaaa aagagatctt gatgcaggat
     5401 gacttgatgt ataacacgaa agcgggattg atgggggcac tagcaggaat cggagatgca
     5461 atcgattcag gaaccgtcca atatattttt atcgcaatcg cggtaccttg ggcacaacag
     5521 ggaagtcctt taggcgcact ttttcctttt atctgctttg ggttgtatca ggttttacta
     5581 ggggtatttt tcgcaagaca agctttcact atgggccgta atgctacagg cctaaagcaa
     5641 aacactggtg ttcagacagc gattgaaatg ctatcagttt tagggttgtt tatgatgggg
     5701 gtgcttgcgg gaaactatgt aaaagtagaa tcttcattga aatttgcgat atccggacgt
     5761 gagtttgtta tccaggaaat tcttgatcaa atcgtgccag ggatattacc tttagctgtc
     5821 gtaatgggtg tgtacttgtt ctatacgaaa aaaggattga aagtcacaca agcattatta
     5881 tggctgactg gaatattaat tgtgctagca ggaatcggta ttttataaaa agaagggaac
     5941 gtgaataaga tgggtgtagt caatttagcg cgtgtggatg agcgtttgat ccatgggcaa
     6001 gtaatggtaa cgttatctca aaaaagtgga gtgaattcca tttttgttgt agacgaagtt
     6061 gtagcaaaag ataaatttat gagagatctt tacaaaaatg caggaagccg tacaggacaa
     6121 aaaacaattg tcattacacc agagaaagct aaattctatt gggatgaata tcaatttaaa
     6181 gaatacaatt gtattttgat cgcaaaaaca gtccaaacga tttacgactt agtaaaacac
     6241 ggaatcccca tggaagaatt gaatattgga gggattgctc aaaaaaatcc tgatacagat
     6301 cttttagtga cgaaatctgt ttatttaaat aaatcagatg ctgaaaaatt gaaagaaatg
     6361 aatgaacaat atggcgtaaa gaatatttat tttcaagcca ctccatctgc acctaaaaca
     6421 ggattaaaag atgtattgaa caagtttgat ttgtcataaa caaatgctta gaaaaaagat
     6481 aaagagggcg aaaaaatgaa gaagaacgag ctgtttcgtg attgggaatt tcgttatcgc
     6541 tatatttacc gtaagcgccg tacaaaaaag agtaaacagc gttttctttc agcattagta
     6601 tcagatattt acagtatgag aacagatgtg acagtcattg cttacgatac gctagcctac
     6661 cgatcaaaaa atatttatgt tggagatatc gaaaaagcag agaaagttat ctgtacttat
     6721 tacgatacac ccgttcatgc attaggaagt tatttcatgt ttgattggaa agaccaaagg
     6781 aaaaaaacaa tctactctat attattgtcc ttcattttgt tgttcagttt aggttggtgg
     6841 ggaatgatga tatataacaa aaatcctcat cacgtattcg atctgctatc cgtataaaca
     6901 ggtatcactg tactagcatt tgggagctac tttttcttat tgggaaaagc agctcgcgga
     6961 tggcctagca gacaaacttt tattcgaaat acttcatcca tattaacgat gctagaaatg
     7021 atccgtacga ttgatgatcc gagtgtagcg tatgcgtttg ttgatgaagg ctgttatgga
     7081 gaaaagggct tagacagcgt gagatcgggt atgaaaaaag aggctattct tttttatcta
     7141 gactctgttg gggcagatac accgctacag ttttcgggaa attatttttc aaataaagaa
     7201 cagtggctga aacaagttga taagttgaaa gaaaaaaacg tcaattatat ttttagtgca
     7261 agaaaaaagc aagcgcagtt cttctatttg accaaaacag atttacgagg gaaaacattt
     7321 aattggcaaa atgccaatca gattattgct ctttttcgat aagtaaaaag tgcaaaacaa
     7381 ggagtgagaa gactaatgtt ggaaatcatg atcgttacac atggtaagtt gagcgaagga
     7441 ctgaaagatg cggcggaagt aattgtcggg acatcgagcc atattgaaac aatgtgctta
     7501 gagtctgggg aggacatcca aacattcgga gagaaggtca aagaaaaatt aactatgatc
     7561 aacacagcag aacccatgct agtatttgtt gatctaatta gcgcaagtcc gtacaatcaa
     7621 gcgctcttgg cagtcaatga actgactgaa gaaaagaaag cagccactta tgtcataggg
     7681 ggcgtgaatc tgccaatgtt gttagaagca atcaatcatc agatgcttca cacaccgata
     7741 gaagaagcgg tggaacaaat tgtcaaacaa ggaaaagata atttaactgt ttggcatgct
     7801 tcagcggaag aaaaaaaatt agatgaggac gatttttaga aggaaggctg aaaagatgaa
     7861 gtggggattt agatggtatg gtgaaaaagg ggattcgatc ccattaaaat atgttcgcca
     7921 aataccggga ataaatggga taattggaac tttgctgact aaaatgcctg gagatgtttg
     7981 ggagatttca gaaattgagg agttgaaagc atctgttgag agccaaggac tggaactgct
     8041 tggaattgaa agtgtagcga tccacgatgc aatcaaggca gggacagatg aacgagatta
     8101 ctatattgat aactatatac gaacaatcaa aaacttgtct cgatgtgggg ttcgattgat
     8161 ttgttatagc ttcaaaccaa tttttggatg ggcgaaaact gatttgttta atgaaaacaa
     8221 cgatggaagc tattctcttt tatacgatca gaaaatcgtc gatcagatgg agccaggaga
     8281 aatgtatcaa ttgatacaca gccagtcaaa gggattcaaa ttgccgggtt gggaagaaga
     8341 acggttgaaa aaattcgctc agctggaaaa actgtatgaa ggaatgaccg aagaagaatt
     8401 atttgaaaat ctgacttatt ttttagaaaa agtgattcca gtgtgcgaaa aagcagatgt
     8461 aaaaatggct atccatccag atgatccgcc atgggaactt tttggttttc ctagagtgac
     8521 gaaaaatctt ggcgacttga agaaaattct aaatgcagta gattctccat ataatggact
     8581 aacgctgtgc acaggatctt taggggcaaa tccggaaaac gatttagttg aaatcatcca
     8641 tgaggtaggt tcgcgcatcc attttgtcca cttcagaaac gtggagtttt taggagaaag
     8701 aaagttcaaa gaaacggcac atccctctac agaaggctcc cttgatatgt atcatattat
     8761 gaaagcgttg gtgcaagaag ggttcgacgg tcctatacgc cctgatcatg gtagaaccgt
     8821 gtggggtgaa gtggctatgc ctggatatgg cctgtatgat cgtgcaatgg gactcactta
     8881 catgcaaggt ctatatgagg cgataagtaa ggaaaaacca ctgggagagc attatgaata
     8941 aaatcaagct cttcatcttt gatatggatg gccttttatt agaaactgga cgtttagctt
     9001 atcgtgctta tgtaaaatca gcacaaaagt atgattatga aatgcgtaag gaagtctatt
     9061 atttactaac tggccaaaca gaaatggcga taagagaaca aatgggcatt ttgtacggag
     9121 aagatgttcc atatatcaaa tggcgagaag caatcaatca atataaagaa aaaatcgtga
     9181 aagaagataa gagagtatat acgaaaaaag gagcagaaga aattttatct tttgcaaaag
     9241 aaagaggaat ccatacaatc gtggcttcgt ctaatacacg ggtaaaagta gaaatgtatt
     9301 taaaaatgga aaatctatat gccttgtttg atcaaatcat ttcaggggat gatgtaaaaa
     9361 aaggaaagcc ggaaccagag atctttttga aagcttgttc aaaaatgaat attcctccaa
     9421 gtgaagcact tgtatttgaa gactcgattg cagggatcga agcagcaagg cgagcgggca
     9481 ttttgtcttt tctcatcaaa gatcatttga tagggttgcc cgatcataat gggaagcata
     9541 agttgaaagt agatgtaagt ttatatgaat ccaataaagc agactatgaa ttttatgacc
     9601 tgcatcaagc aaaacgattt ttagaaagta aagggttgta tctctaataa agaggactat
     9661 tttctagtcc tctttattta ttgtcctgca cgactgaggg aacagatgaa aaagaagtaa
     9721 ttttttattt tgaagtatct accttatttg tagtgaacaa tttagaacaa acacaaaacg
     9781 catctactgt tatctaccag tagatgcgtt taaagagaag aacgagaatc gtccatatga
     9841 gggtttccac tccttatgca gattttttta attcttgcac tgcttgttcg atcgtaacac
     9901 ctgtcgctac atgattggta ttttctttgt caaaaacgac aaatagattc aaatctgtat
     9961 ccaaggttac tcgatattgt atatctttgt tatagaatgt catagccatt ctcctttctt
    10021 taaatacttg ctgaaaggca acgaacgcgt tgataacgaa attccattta taagtatacc
    10081 accaattgaa aggttttcat agttaagaaa ttttaaagtc aaaagttgca gataaaagca
    10141 aataaacaag aaaacaaaaa gtgaatcaat cgcggttatt caactttttc ttcgattcga
    10201 agacaataga agacaatgaa atttatattt cattgcatta tccttgtgtt attagaaaaa
    10261 gcatgatata ttaaatgagt aatctatttt gaaacgtaat ttgagcgata tatctacata
    10321 gataaaactc cttttgccta tcaaatattt attgcaacga aaaaacgtac attgatacgt
    10381 atcaggagga atttatttat gaataacggt acagtaaaat ggttcaacgc agacaaaggt
    10441 tttggcttta tcactggtga agatggaaat gatgtatttg cacatttttc agctatccaa
    10501 ggtgacggct tcaaaacttt agaagaaggc caagcagtgt cttacgatgt tgaagatggt
    10561 caacgtggcc ctcaagcaac aaacattgtt aaagcttaat aaaaattgac ttttaaccgt
    10621 cttttcgaaa gaaaa
//
LOCUS       DADLIO010000089        10517 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.092, whole genome shotgun sequence.
ACCESSION   DADLIO010000089 DADLIO010000000
VERSION     DADLIO010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10517
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.092"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(133..306)
                     /locus_tag="JOX41_002480"
     CDS             complement(133..306)
                     /locus_tag="JOX41_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAY6450179.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
     gene            754..3116
                     /locus_tag="JOX41_002481"
                     /pseudo
     CDS             754..3116
                     /locus_tag="JOX41_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
     gene            3484..4407
                     /gene="truB"
                     /locus_tag="JOX41_002482"
     CDS             3484..4407
                     /gene="truB"
                     /locus_tag="JOX41_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HAY6450180.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            4411..5352
                     /gene="ribF"
                     /locus_tag="JOX41_002483"
     CDS             4411..5352
                     /gene="ribF"
                     /locus_tag="JOX41_002483"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HAY6450181.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            5704..6489
                     /locus_tag="JOX41_002484"
     CDS             5704..6489
                     /locus_tag="JOX41_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAY6450182.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            6502..7353
                     /locus_tag="JOX41_002485"
     CDS             6502..7353
                     /locus_tag="JOX41_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HAY6450183.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(7477..7929)
                     /locus_tag="JOX41_002486"
     CDS             complement(7477..7929)
                     /locus_tag="JOX41_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAY6450184.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(8394..8762)
                     /locus_tag="JOX41_002487"
     CDS             complement(8394..8762)
                     /locus_tag="JOX41_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chaperone"
                     /protein_id="HAY6450185.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            8912..9394
                     /locus_tag="JOX41_002488"
     CDS             8912..9394
                     /locus_tag="JOX41_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HAY6450186.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            9431..10441
                     /locus_tag="JOX41_002489"
     CDS             9431..10441
                     /locus_tag="JOX41_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HAY6450187.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
BASE COUNT         3576 a         1748 c         2192 g         3001 t
ORIGIN      
        1 aaatcagggg ttgcgggatt tttttgtttt cattaagacg tattacctaa gagttccatg
       61 actttagtct tgcggcgtgt cagctaacca aaaaagagaa aaagaaaagt aaaaaattcg
      121 actttctttt ttctagtagt atataaattt ttgcatatag ataaagatca agataccgat
      181 aacggaagct agattgtaat ctattttagt gacagtcagg tatagccaag taactagaag
      241 atcagtggaa cctgcaccat aaaagtttga gtttgtcggt ccgttgacag ttaaaagaaa
      301 aatcacgttg aagttattga tatttccgat tacgccgctt cgatttggtc acgatccaaa
      361 ttttggataa tccctgtaga aattagcata gtagctggga taccaattca catattgaca
      421 aagataacag agacttttac ataaaacgga tcaatcagga aaggaattgc tcgatccagc
      481 cccagttttc cagcaatgtg ttaactggcc cagcgtcatt cagcaaatta tgcatgatga
      541 ggagcgaaat gaactgcgga acagccattg tgataacgac aagttttttg gatcaatgta
      601 aaaaacgtca gcgaaaggaa aaatttcgtg gttttttata cctgttcatt tggctagata
      661 taaaatccaa acaaatgaac agaagtgctt attaggtttc aattgggagt atctgcgcta
      721 gaataagagt aataatgaaa aggagtgtta tgtatggatt attctagtaa agaatacttt
      781 gataaaatga cggcttggtg gcgtgctgct aattatcttt ctgttgggca actttatctt
      841 aaagataacc ccttactgag acgtacactg aaacccgaag atgtcaaaaa acatccaatc
      901 ggtcattggg gaacgattcc tggccaaaat tttatttatg tccatttgaa ccgagtcatc
      961 aataaatatg atttgaacat gttttatatt gaagggccag gacacggcgg acaagtcatg
     1021 gtatcgaatg cttatttaga tggaagttac acagagatct atccagaagt aacggaagat
     1081 gagacaggaa tgcaaaaatt attcaaacga ttttcatttc ctggaggcat tgcttctcat
     1141 gcagcaccag aaacaccagg ttctatccat gaaggcggag agcttggata ctctctttca
     1201 catgcagtcg gagctgtatt agacaatcct gaagtaatct ctgctgtcgt gattggtgat
     1261 ggtgaagcag aaaccggtcc tttagctgga agctggttct caaatgtctt tatcaatcca
     1321 gtgatagatg gagctgtttt accgatcctt catttaaatg gtgcaaaaat agccaaccca
     1381 acgatcttgg cacgtaaatc agatggagaa ttagcaaatt actttaacgg acttggctgg
     1441 gaacctttct ttattgaagg aaatgattca gaaaaattaa atcctgttat ggctgaaaaa
     1501 atggatcaag caatcgagaa aattaaatcc atccaaaaag aagctcgcct gaagacagca
     1561 acagatgtcg tgatgccaaa atggccagta ttgatcgtac gcacaccaaa aggatggacc
     1621 ggtccaaaag aatgggacgg ggaaccaatt gaaggaacct tccgagcaca ccaagtaccg
     1681 attcctgtag atcaagaaca tatggatcat gcagatgctt tactccgttg gctgaaatcc
     1741 tatgaaccag aaaaattatt tgatgcacaa ggacgtattt tagaagaaat cagagaaatc
     1801 gcgcctactg gtgaccaaag aatggcaaaa aatcctatca ccaatggtgg aatcgatcca
     1861 agaccgctta ttatgccaga ttggaaaaaa tatactttgc aatttgaaaa accaggctcc
     1921 gttaaagcag aagatatgac cgaacttggt aaattcgttc gcgagatcat tgagaaaaat
     1981 ccagaaaatt tccgtatatt tggaccagat gaaacaaaat caaaccgatt gaatcaagtt
     2041 ttcaaaacga caaatcgcca atggatggaa aaaatcgaac cagaaaatga tgaatggctt
     2101 tcgccatctg gtcgcgtcat cgacagtcaa ttatcggaac accaagatga agggttctta
     2161 gaagggtacg ttctgactgg acggcatggt tttttgcaag ttacgaatca ttcttgcgag
     2221 tggttgactc tatgttgact cagcacttca aatggatgcg gaaatcacat gacctttctt
     2281 ggcgaaatga ttatccttcg ctaaatctca ttgcaagctc aacagtcttc cagcaagatc
     2341 acaatggata tagccaccaa gatccaggaa tattgacaca tttggcagaa aagaaggcgg
     2401 agttcatccg tgaatatctg cctgcggatg caaatacatt gctcgcagtc atggataaag
     2461 cattccgctc gtcagaaaaa atcaatttga tcatctcttc caaacatccg cgtgctcaat
     2521 tttactcagc agaagaagca gccgtcttag tgaatgaagg cttgaaaatc attgattggg
     2581 cttcgacagc aaaagaggag gaacctgaat tggtcattgc tgctgcagga acggaatcta
     2641 acttagaagc attagcagct gtaactttgc tgctggaaga attcccaaaa ctaaaaattc
     2701 ggttcatcaa tgtcgtagat ttattgaaat tacgtcatcc aagtcaagat ccgcgtgggt
     2761 tgagcgatga agaatttgat caatatttta caaaagacaa accgatctta tttgctttcc
     2821 acggttatga aacattggtc cgcacgattt tctttgatcg tcataaccat catttaatga
     2881 ttcatggcta caaagaaaat ggagatatca cgacaccatt tgacatgcgt gtagtaaatg
     2941 aacttgatcg ttatcatttg gcaaaagacg cagctttaaa aatcaaagga agtcaagcag
     3001 aagattttgc gaaaaaaatg gatcagaaat tacaagaaca tcaaaactat attcgtgaaa
     3061 atggtattga tctgccagaa gtattggatt ggaaatggaa aaatcttgac caataaaatg
     3121 ataaaatcga tcccgcaaaa tagaattttt tacattgatt aagaaactga aaaaataaat
     3181 aaaaaaaacg gaaaaaagac tggaagaatg gccagtcttt tttttcgttt ttgggaagtg
     3241 aaaaccaaac tatttacctg taagccaccc ataaatccaa tcaaatggtg caaagaaaaa
     3301 atcttccatt ctattccctc ctttaaaaaa gcataacatg atttctattt acgtgagcat
     3361 gaattttgtt acgtttttat tgccgaaaaa taaaaaccgt tcattatgat gtcaaattcg
     3421 tcagtaattg atgcaatgtg ttataataat tcagttaaat caaaaatgaa atggagaaaa
     3481 gacatggacg ggttattacc tttatggaaa gaacgcggaa tgacaagtca tgattgcgta
     3541 ttcaaattaa gaaaaatctt acatacgaaa aaaatcggac atgggggtac gcttgaccca
     3601 gacgtagacg gtgtgttgcc catttgtatt ggaaaagcca caaaagttat cgaatatttg
     3661 acagattctg ggaaaatcta tgtaggcgag ataactctag gtttcagtac aacgacggaa
     3721 gatcgatccg gagaacgggt agaaacaaaa ccagtagata tgtctttatc tgaaaaaaaa
     3781 atagatgaag tgatggcttc atttattggt gagatcaccc agataccacc aatgtactca
     3841 gcggtaaaag tcaacggtaa gcggttatat gaatatgccc gcaataatga aacagtggag
     3901 cgtcctgtta gaaaggctca gatttaccgt tttatccgga caagtgaatt gacaagagac
     3961 gaagtgacag gaaccatttc ttggcgcttc gaagtagaat gcgggaaagg aacctatgtc
     4021 cgcacattag ctgtagatac aggcaagaaa cttggttacc ctgcgcacat gtctgatctg
     4081 acccgaacag caagtgccgg tatgtcccag aaggatgctc tgacattaga agaagtagct
     4141 caagctgtga aaaatgggac aatcgatgat tgtttgctgc caatagaaaa aggagtggaa
     4201 cggttcaaac gagtagatat tactgatgaa gtatggcaga aagtaaaaaa cggtatgaga
     4261 cttgattata ctgtatttgc gctcccagaa atgccgtcag aagaaattgc tttgttttat
     4321 aaaggaaaag ttgtcagtat ttatcagcca aacccgaaag aaaaaaacaa attaaaacct
     4381 agtaaagtat tgagaaatga ggaataacga atgaatatca tcaagatcag acatccttac
     4441 caatcagaac aaattccaga agacgatgtc gttttagtgc tgggattttt cgacggcgtg
     4501 catatcggac accagaaagt cataaagaca ggtatggaaa ttgcacaaaa agaaggattg
     4561 aaattagcat tgatgacttt caatcagcat ccatctattg tctttaaaaa gatcgatcct
     4621 agcagcgtga aatatttgac tagccttaag caaaaagaag aaaaaatggc cgctttgggt
     4681 atagattatt tatatgaagt tgattttact tcttcttttg ctcatttagc accgcaggaa
     4741 tttgttgatc aatacatcgt agggttacat gcaaaatatg ctgtttccgg ttttgattat
     4801 acgtatggac caaaagacat tgcagatgtc gctcattttc ctgaatatgc caaaggaaga
     4861 ttcaaaatcg tcacagtttc taaagaagaa gaacaaggtg aaaaaatcag ctctacccgt
     4921 attcgtggat tactagacag cggacaagta aaagaagcag caaaactatt aggttgcaca
     4981 tatgaggtag aaggggtagt tgtccatggc gatgcacgag gcagactact aggattccct
     5041 acagcaaatg tcaaagtaaa gagcacggtt catttgccta aagaaggtgt ttatgtgtcg
     5101 gaaataaaaa ttggggaaac atggtatcca gccatgggtt caattggaca taatgataca
     5161 ttcggtgaag gacgggagct gactgtagag ttgtatattt tggactttaa tcaagatatc
     5221 tatggtgaac atgtcgcggt acgctggaat caatttttaa gagatcaagt gaaattttct
     5281 agtgtagagg aattgattga acaactcaag gaggatgaac aagcaacagc tgaatatttt
     5341 tctcagcaat aaaacattat gcataaaatc tcttgtttat gtataactag caattacaat
     5401 aaaatgggtg ataaataagc ccaggaaagg ggctgtgaca aaagtcttgt cacagccttt
     5461 ttttccaaat aaatggtttt tcagaagtag cttcttcgga aataagccga aatttcttga
     5521 agctgaccac ttctgtcaca acctctttct ttatagaaat aaaaggacac tagcaattca
     5581 tgaaaacgat tgctagagcg tatcatttgc tttagactat atatcttggt gtacactcac
     5641 tttaaggcgg aaataaaagt tatccgtaat aacaggttta ggtatgaaaa aggagtgggt
     5701 actatgtaca aggaattaga aaacaaagtc gcagtagtaa ctggtggctc aaaggggatt
     5761 ggaacagcga ttgctcaacg attcgggaaa gaaaaaatga atgtagttgt caactataac
     5821 tcggataaag aaggagcaga aaaagcagtc aaagcaatcg aagaggcagg cggaaaagca
     5881 gtctctgtac aagcagatgt cagttctgaa gaaggaatac agcgtttact tgatacggct
     5941 ttagaaaatt ttgggacact ggacgtttgg gttaataatg ctgggatgga aaatcagcat
     6001 ccaacccatg aacttagcct tgaagattgg gaaagagtgt taaaagtcaa tttgactggc
     6061 gtttttatcg gaacgaaagc ggctttaaat tactttacag agaataataa aaaaggaaat
     6121 atcatcaata tgtcttctgt tcatgaacag atcccatggc caacgtttgc tcattacgct
     6181 gcttcaaaag gcggggtaaa attatttacc gaaacggtag caatggagta tgcaccgaag
     6241 ggaatcagaa tcaatagtat aggccctggt gctatccgta cacctattaa tgcggcaaaa
     6301 tttgatgatc ctgaacaaaa agaactcttg gaaagtatga tcccactagg acgcgtaggt
     6361 gaaccaaaag aaatagcggc gacagctgca tggttggctt cagacgaatc cagttatgtt
     6421 acaggtatta cactatttgc agatggtggg atgactttat atccttcttt ccaaggtgga
     6481 aaaggataag ggtgaataaa aatgggttta ttgattgcat tgatcccggc agttggctgg
     6541 gggatccagc cactgatttt gaaaaagatt ggtggcagac caacaaatga gatattagga
     6601 actggtattg gagcggtgct tgtcggctta ctcgttcaat tattcgcttc tccagctggt
     6661 atttcagtga ctacattttt gattagttta ctttctggtg cattttgggt tattggacaa
     6721 acaggacagt atacatcttt caacttgatt ggtgtttcta aaacgatgcc aatttcgact
     6781 gcattacagt tagtcggaac ctcgttgatt ggtgtcttcg cttttggaga atggtctgga
     6841 agtatgggga aaatcattgg agcagcagca atcattcttc ttgtatttgg ttctgcttta
     6901 acggcaatca gtgatgatcc tggaaaaaaa ggcggtatca caaaaggaat tagtctatta
     6961 gcatcaacaa gtattggtta ttgggtatac agtgcattgc ctaaactagt tgatgcaagc
     7021 ggactttcca ttttctttcc gcaaatgatc ggtgtctttt taggggcagt gatttatgtg
     7081 attttccgta aaccaaccgc attttctgaa gacaagagtt ggaaagcaac gatcgttgga
     7141 gccatcttta gtgtgtcagc attggcttat attttttcag caaatgaaaa tggggttgct
     7201 actgcatata tcattacaca gctaaacgta gttatctcta cattaggcgg tatgtacatc
     7261 ctgcatgaaa ataagacacc aaaagaaaaa aaattaacga ttatcggatt attgctgatc
     7321 gtagtaggaa gcatggtcac ggtctttatt tgaggataaa gatggtaaaa tttcatttat
     7381 taaaaaaata tttgtttgaa ccaaacagta agtacttata aaaaaatagc gctagaattt
     7441 ccaacatctc tggaatttct agcgcttttt aattgtttaa gatacaaggg aaatatctgt
     7501 ctggatcaat aatttttcat tgatccattg actaaagttt acgacataat tgaagttacc
     7561 accgattagt atctccgcat gattgtcttt ataaagatcg tattgtaaaa gacggtcttt
     7621 tttatttgcg taaacatcgt tatggtactg gactaattgt tctcggaatt gattgattgc
     7681 tgtaaaatca cgatattgaa ggttgaaacg catcgtgatt ggtgcattta gcatgaatcg
     7741 ctgcatttct tttgctgctt cctctgcttg atctccgtat aggaactcaa aaagattacg
     7801 ttcagaaaat ttccattgcc cgccaacctt tgttcctttt agttttcctt catgaagata
     7861 atttctgata gaacgtgtag taacacctaa ttgttcggct aattcattta ctgagtaaaa
     7921 atctttcaat gttcaccctc ctatgtgaat ggttctactg acttagttga tatttgctta
     7981 atcacgaaat gtagaaagaa cgattttaat taaggtcatt gtaaaaatca agtcagaaaa
     8041 ttctaacttt tatttctcta aagaaattcg ttctctccta aagtgatatt atatttaaat
     8101 atacctgaaa ataatgggca gtattatgaa agatcactga tattttctcg tattttttcc
     8161 ttattcaaaa gttttgcagg aaaattgctg aaaaaataat tttactaagt agaaaattca
     8221 aagccattca atcagtgatt tttttcagca caagaaagac tccttataaa aatagcagat
     8281 actttgtcaa ttaagtgttt aaccagggat gataaaaagg ataggattga acaaaacctg
     8341 tataaggtga tgaatagttt cctcgccagt aaaaggttta ttcgtataaa gctttatcgc
     8401 caaaatttat catgaccttt tttatcttca atattaaatg aaatcaattg ttcaatcaat
     8461 tcccagttga ttacactttt ccaaggaact ttgatgacgt tatccgtata tacgtagcct
     8521 gcttcttgga tatttttttc aagggcacga atcgctgctt tttccggtgc gatagaaaaa
     8581 tgatttttag caaaactaaa tgcaataata aaggtaccat ggtcagtaaa cataggttgg
     8641 ttccatttta cagttgtgtc tagctgggga tacgtttctg ttatcttagc aaaaaggtct
     8701 ttgatctttt gttgatgttc tttttctttg atttgattga tgatcggctg aaatttttcc
     8761 attctaaaac gcctccatta agtggtttga tttattttac cagaaaaaca atagttatgt
     8821 ataaaaaacg aacaaaacac aagtaatgtt gtaaccgcta tatttatatg ataagatgtc
     8881 tcaaataata aaatagaaaa gagacataaa aatgattgac ttggcaaaga aattcttaca
     8941 cgaaaatata tattttgagt tgtatcatca tcgagccatt tatacaaatg aagatgcttt
     9001 ggtaataaag aaagaacaag gatttacagg tacagagacc aaaagcttat tcttaaaaga
     9061 taaaaaagat aataactacg tatatctgac ttttactacg aaacaaacgg atttcaaagc
     9121 attagggaag atcgtcggta aaaggctttc tattgtttca tcagaacgca tggaagaaca
     9181 aacgggacaa aagcagggcg ctgtttctcc gtttggttat gaaaaacaga ttccgattat
     9241 tattgatgaa gagctcttat caaatgaaaa acttgttttt gcaccaggta gaccagatca
     9301 aacgatggtc atccaaacgg ttgacttaaa caaaatcatc cagctacttg agatgccgat
     9361 atttttgatg ccggcaaacg aaaaaaacaa ttaaccaagt aaaatagtgc atacttggag
     9421 gtgaagcaac atgataagtt atccattatt agaaagaaat gcaacgattg gggttactgc
     9481 accatcctca ggcgtatcag aggaacacca ttcgttactc gaatcagctt taaagagaat
     9541 ggaagaaaaa tctttccaag tagttactgg aaagacgctt tggacgcaag ataaggaaaa
     9601 atcaggtcca gcaagaaaac gagcagatga attcaatcaa atgatgcaag atgaaaatat
     9661 ccaaatgatc tttccgactt ggggaggaga attattgatt gagattctcg attttgtcga
     9721 ttttgatgct ctacaaccaa aatggatagt aggttattca gatattagta cgttgctact
     9781 tgctgtcaca ttaaaaacag ggatagccac tgcacatgga actaacctta ttgatttaag
     9841 aggagagtac ttggatgaaa cgacagcaat gtgggaaagt gtactgaaaa caagagaagg
     9901 agaatcgatt ctacagcaat cttctgaaaa gtatcaaaaa gtgtggcccc atgagcattc
     9961 atcatcttct gttttccatc tcactgaacc aacaaattgg caatcagtca gcggagatgc
    10021 agtaaggatg aagggacgat tattaggtgg ttgtattgat acgatcaggc atttaatcgg
    10081 tactccttat ggagatgtcc aatcttttaa aagaaagtat aatgatggaa agccgatctt
    10141 gtggtttcta gaaaactgtg agctatcgtc agttgattta agaagatcac ttgttcagat
    10201 gaaactggca ggctggtttg atggcagctc ggggatcatg ttcggtagaa gtgcggcaga
    10261 ggatttgtta gattataaaa tgaaggatgt atacgaagat ctgtcaaagg aattaaaact
    10321 accgatcttg tatgatattg attgtggtca tgtaccgcca caactgacat tgattaatgg
    10381 tgcctatgca gaagtagcgg tagaagatag aaaagcgact gttttgcaaa cgtttattta
    10441 aaaaattttt tcctgccttg gagtctatca aagaccaata aatctaaata gaaaagaaag
    10501 tgaaagaagc tgacaaa
//
LOCUS       DADLIO010000090        10372 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.093, whole genome shotgun sequence.
ACCESSION   DADLIO010000090 DADLIO010000000
VERSION     DADLIO010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10372
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.093"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            176..2785
                     /gene="clpB"
                     /locus_tag="JOX41_002490"
     CDS             176..2785
                     /gene="clpB"
                     /locus_tag="JOX41_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HAY6450188.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(2936..3607)
                     /locus_tag="JOX41_002491"
     CDS             complement(2936..3607)
                     /locus_tag="JOX41_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450189.1"
                     /translation="MIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGITFIVES
                     LLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWDKILHA
                     VSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLCDQFLG
                     MNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFESYKLE
                     KVKNT"
     gene            complement(3600..4094)
                     /locus_tag="JOX41_002492"
     CDS             complement(3600..4094)
                     /locus_tag="JOX41_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HAY6450190.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(4114..5334)
                     /locus_tag="JOX41_002493"
     CDS             complement(4114..5334)
                     /locus_tag="JOX41_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAY6450191.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            5481..7316
                     /gene="lepA"
                     /locus_tag="JOX41_002494"
     CDS             5481..7316
                     /gene="lepA"
                     /locus_tag="JOX41_002494"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HAY6450192.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            7512..8423
                     /locus_tag="JOX41_002495"
     CDS             7512..8423
                     /locus_tag="JOX41_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAY6450193.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGKLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEILKEINRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDY
                     KNILPKDERVSDFKKINSFSMGLRMRKIRKDYYLEREEFGKLFSPSISKWSIDRYENG
                     RDIPNTNRIIQYAYIGNLSLEFLIYGI"
     gene            complement(9363..10322)
                     /locus_tag="JOX41_002496"
     CDS             complement(9363..10322)
                     /locus_tag="JOX41_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAY6450194.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVFLSYVTKDDLSNLI"
BASE COUNT         3463 a         1806 c         2074 g         3029 t
ORIGIN      
        1 ctcttttttt atatacatac aatcaatttt gtttttttaa gatttatata agtcgagaaa
       61 aaaagtcaaa aaactatgtg tatattttga ccaaaattga ccaaagcgat ataatagttt
      121 ttgtaaagat caaagaaata agtgatctta cctttaatta ggagggtata cctgtatgaa
      181 tattgagaaa atgactacga cgcttcaaga agcgattgct gaagctcaac agattgcggt
      241 cactcgaaaa catcaagata tcgacattgc ccatgtatgg aaaatctttt tacaatctaa
      301 tcattttggt cgaaatttct atacggatgc cggattggat gtcgaatctt ttgaacatga
      361 aattgatcgt ctactggatg agtatccagt tgtttctggt ggaaacgtcc aatatggaca
      421 aaacctcagc cagaatttct ttcgattatt gaatgaagca gaccaaatac gtgaaagctt
      481 cggcgacgag tttctttcaa cggaagtcgt tattttagcg ttgatgaaat taaaaaatta
      541 tccgttaact gtttatttga ataaaaacgg attatctgaa aaagaattgc gtaaaaacat
      601 cgaagagatg agaggaggag aaagagtgac ctcacaaaac caagaagaac aatacaaagc
      661 attagaaaaa tacggcgttg atttagtaca gcaagtcaaa agcggaaaaa tggatccaat
      721 catcggtcgt gatgaagaaa tccgtgatgt catccgtatt ctttcacgaa aaacaaaaaa
      781 taatcctgtt ctgataggag aacccggtgt agggaaaacg gcaatcgttg aagggcttgc
      841 tcaacgtatc gtacgcaaag atgtgcctga aaatttaaaa gataaaacga ttttttcatt
      901 agatatgggt gcattgatcg ctggagcaaa attccgtggt gaatttgaag aaagactaaa
      961 agcagtcttg aaagaagtca aaaaaagtga tggacgtatc ctcttgttca tcgatgaaat
     1021 ccacaatatc gtaggggcag gaaaaacaga aggaagtatg gatgccggaa atctgttgaa
     1081 accaatgctt gctcgcggtg aattacattt gatcggtgcc acaactttag atgagtaccg
     1141 tcaatatatg gaaaaagaca aagcgttgga acgtcgcttt caaaaggtat tagtcaaaga
     1201 accaacagtg gaagatacga tcagtattct gcgtggatta aaagaacgtt ttgagatcca
     1261 ccatggtgtt aacatccatg acaacgcatt agtagcagca gctactttat ctgaccgtta
     1321 tattactgat cggttcttac cggacaaagc aatcgatttg atcgatgaag ccagtgcaac
     1381 gattcgggta gaaatgaact ctatgccaac ggaattagat caagttacta gacgtttgat
     1441 gcagttggaa atcgaagaag ctgcactgaa aaaagaatca gatgatgcaa gtaaaaaacg
     1501 cttgaaaaat ttgcaagaag aattagctga acttcgtgaa gaagcaaatg cgatgaagat
     1561 gcagtgggaa acagaaaaag aagaagtcaa ttctgtttca gcaaaacgtg ctgaaatcga
     1621 taaagcaaaa cacgaattag aagatgcaga aaataactat gatttagaac gcgctgctgt
     1681 attgcgtcat ggtacgatac ctcaattaga aaaagaattg aaggaattag aagctaaagc
     1741 aaaagacagc gagattaaga tggttcaaga gtccgttacc gaaaatgaga ttgctcaagt
     1801 cgttggcaga ttaacgggta tccccgtaac gaaacttgta gaaggtgaac gagaaaaact
     1861 aattaaattg aatgaaacac ttcataaacg agtgattggt caagatgaag cagttgatgc
     1921 ggtcagtgac gcggtaattc gttcacgggc tggattgcaa gacccaaatc gtcctctagg
     1981 ttctttcctt ttcctaggac caactggtgt cggaaaaacc gaattagcga aagcgttagc
     2041 tgagaacttg tttgactcag aagatcatat ggtacggatc gatatgagtg aatatatgga
     2101 aaaacatgct gtgtctcgtc tagtcggagc tcctccaggc tatgtaggtt acgaagaagg
     2161 tggtcaatta acggaagctg tcagacgaaa tccttataca atcgtcttgt tggatgaaat
     2221 cgaaaaagcg catcccgatg tcttcaatat cttgttacaa gtcctagatg acggacgctt
     2281 gactgattca aaagggcgag tagtagattt caaaaatacg gttctgatca tgaccagcaa
     2341 tatcggttca cagttactgc tggaaggcgt gactgctgat ggaacgattc cagaagcagt
     2401 ggctgaacaa gtcaacacgc tattacgtgg aaacttcaaa ccagaattct tgaaccgaat
     2461 cgacgacacg attttattta caccattgag cctagacaac gtgaaaggaa tcgttgacaa
     2521 aatggtggcg caattggcac aacgtctgga acatcaagaa atcctgctga caatcagtga
     2581 tgaagccaaa acgtggattg ctgaaaatgc ttatgaacca gcatatggtg caagaccatt
     2641 gaaacgattt atcactaagg aagtagaaac accactagct aaagaaatcg ttgcaggaca
     2701 tgttatgcct aaatcaaaag taacgattac tttacttgat ggacaacttc atttcaaaac
     2761 agaagagcta gaagaaatcg tctaatcttc cattgagact ataaaagaaa aaaggggtct
     2821 gacacaacta gtgtcagacc tccttttttc aaataaacag tgttccagaa gtagtttctt
     2881 cgaaaaataa gccgaaattt cttgaagctg cccgcttctg tcacaacctc ttttattagg
     2941 tatttttcac tttttctaat ttataacttt caaagtaacg ctcatctttt ttactttgag
     3001 accatgcaaa caatcccatt aaggcagcac ctatcgtatt tgtcagcaag tcgcccatcg
     3061 tatccatcaa tgctgctcgt ccgacaaaca gtgtgccatc agaagcagca aaacgttgaa
     3121 gattcatgcc taagaactgg tcgcataaga attcccagaa ctcccaaaac acgccgcaaa
     3181 gtccagcaaa cgcaaagccg aataagagga acaaccaagg actggttttt gatatctcag
     3241 catctttcat caagtaacca atcaatccat agccaagagc tgtcaggacc attggactca
     3301 ccgcatgtaa gattttgtcc caaaaagaga tgatactgat caaatgcatc cctgtgccta
     3361 aaaagacaga gatgaacaag aaaaaccagt aaaacaaaac gattgctgct ggtattttaa
     3421 gtttgaaaac tttcaaaatg acttgtggca tgaaaatcaa tgcaatccct aataaagatt
     3481 ccacgataaa tgtgattcct tgagaagtcg aatatttttg tgtgataaat tcataaaaat
     3541 tatagcagac aacgaataca ccaaaagcaa gtaaagctat ttgcaccttt ttgatttctt
     3601 taatcactga aagtccctcc atctaaaaat ctttttactt ctgaaagcaa ctcaatttct
     3661 gaagaaacca cttttccgtt caatttgatc aaacctattg tatataagtt caggtagtga
     3721 aattgatttt cagctgtttc ttgtagtgca gcgatttttt tcgggtgggt tccgccttgc
     3781 tgtcgagtat cagtatataa gccgatcact gggatgcctt tcgcataagc cacaccgatt
     3841 tccgatgcta ccccggcatc gatcgtcagc ccatctagta aagcaatcat taaatcacta
     3901 gccaacactt tttctgtgtc agcaagagca atcattcgac tgtctgcata agcagttttg
     3961 tcattgattg cttcattttc ttgaggaaga tagatcgaaa gctcagaaga gagctctctg
     4021 atttctttaa ctaactgttg gttatataac aaatcacttt tagcaaacat tggtgcggca
     4081 aaataaattt tcatctaaac atcatccttt ttatcaaaaa taatcgctaa agtaagcttc
     4141 catgtttgga atgatacgct ctagtgactt cagtgtttct tcatctgttt ctaaccgttc
     4201 gattcttgcc aaataagaag cacggcgata attcatcatc aagcaagtca atgtttggat
     4261 atccagtcga acggattttc ctataggttc atttaagaca cggacttgtc cctgttcatc
     4321 ccatgttaaa gcgaagacac cattattcca aggagcgaca ggatcttcaa tgatgaaatg
     4381 aaaagcatca gctgttccaa caaacggaaa ccgttgaagg aattctttta catcaacgat
     4441 ccgagccata aaatatggtt cgatctgctc tttgatctga ctatcttcaa tcaaaaatgc
     4501 taaaggctca tttttataaa tatctccatg tacccagtag atcatggaaa aatgtgcgga
     4561 aataaagttc cataagccat ttcgagcttc ttgatcaaga tagaacattt cttttacgtg
     4621 aaatatttct tcagctaccc agtagaacag aacacctctt ggttcatggt tgctatcgta
     4681 gtagacagcg gctgtgcgct catcttcatt ttcgaaacgc caatactctt cccaatgaaa
     4741 atcactgcgg aataaagcac catggttttg ttgggcaaat ttgtcataaa cggaaaatac
     4801 gtctggatga tcaactggta atcgctcaac cataccactt actgggattt gtttaggtag
     4861 ctgtgtatct ctgattttaa aggaaagttt atcagacatg atttcccatc ctttacgccg
     4921 atagtagggg atactgtaag gatacaaata agagatccat tgcttattct tgcgcatatt
     4981 atccaatgca acgataatta gatcttgcat caatccatgg ttagcatatt ctggataagt
     5041 tccaactcca gtcacaccac ccattttata acgtgcaccg tgaatattga cttcacaagg
     5101 atagatagcg atttgagaga tcagtttatt ttcgtggaac catccgaaca ctttcgatac
     5161 ttccaaaatc ggttttttgg aacggataaa agctcgttta ttctcaaacc cgctttcctc
     5221 gatgtctgct tcagtcactt ggaacacata ggaaagcaat tcattgaatt gatcgatatg
     5281 ttcttgagtg accggtttta attcaagatt ttctctaaaa tctttttgat ccattttttc
     5341 atctccattt attagcttga taacagtata gcaaaattct acaaaaaaaa cttctatagc
     5401 tgactaatta aaaactcttt aaattactgc ttttcgttgg tataatggaa agtgctgatt
     5461 atatgaaaag aggagacgct atggatataa agaaaatgaa agaacgccaa gagcagattc
     5521 gtaatttttc gatcatcgct catatcgacc atgggaaatc tacattggcc gatcgtattt
     5581 tagaaatgac gcacactgtg acgtctcgcg aaatgcaaga tcagctgtta gactcgatgg
     5641 atttggaacg tgaacgtgga atcacgatta aattaaatgc tgtagaactc aattacacag
     5701 cgaaaaatgg agaaacatat atctttcact tgattgacac cccagggcac gtcgacttca
     5761 cctatgaagt ctctcgaagc cttgctgcct gtgagggtgc cgttttagtg gtcgatgcag
     5821 cacaaggaat cgaagcacaa acattggcca atgtttattt agcgttagac aatgatttgg
     5881 agatcctgcc agtcatcaat aaaatcgacc tacccgcagc agatcccgaa cgtgtccgtc
     5941 aagaaatcga agacgtaatc ggaatcgatg ctagtgaagc tgtattagcc agtgccaaat
     6001 cagggattgg gattgaagat attctcgagc agatcgtgga atatgttcct gcaccaagtg
     6061 gagacttaga tgcaccgcta aaagctttga tctttgactc tatttatgat agttaccgcg
     6121 gtgttgttct aaatgtccgg atcacggacg gtatggtcaa acccggagac aaaatcaaac
     6181 tgatgagtaa tggcaaaaca tttgatgtta cagaggtcgg ggtcttctcg ccaaaagcag
     6241 ttgctagaga ctttttgatg gtcggtgatg tcggttatat cacagcaagt atcaaaactg
     6301 tccaagatac acgagtaggg gatacagtaa cgttagcaga caatcctgcc gctgaagctt
     6361 taccaggtta ccgaaaaatg aatccgatgg tttattgtgg tctttatcca attgatactt
     6421 ctcgttacaa cgatttgcgg gaagctttag aaaaactgca attgaatgat gctgctttac
     6481 aattcgaacc agaaacctct caagcattag gttttgggtt ccgctgtgga ttcctcggac
     6541 ttcttcatat ggatgtcgtc caagaacgct tggaacggga attcaatcta gaattgatca
     6601 cgactgcacc atccgttatt taccatgtta ataaaacgga tggtacgact gctacagtag
     6661 ataacccggc agattttcct gaacctgtaa cgattcagga tgtagaagaa ccattcgtca
     6721 aagcacagat catggtccca aatgattttg tcggtgcagt aatggaactt tctcaacgaa
     6781 aacggggaga attcattacg atggattatt tagatgatta ccgagtaaat gtcgtctata
     6841 atattccgct ttctgaaatt gtctttgact ttttcgacaa attgaaatca agcacgaaag
     6901 gctatgcctc attggattat gaaatgtctg gttatcaaaa aagcaagtta gtgaagatgg
     6961 acatcttgct gaatggagaa aaagtcgatg cattaagctt tatcgttcac cgagactttg
     7021 cctatgaacg tggaaaagca atcgttgaaa aactgaaaaa actaatccca cgccaacaat
     7081 ttgaggtgcc aatccaagca gctattggac aaaaaatcgt tgcccgttca gacatcaaag
     7141 ccttgcgtaa aaacgtcttg gctaaatgtt atggtggaga tgtttctcgt aaacgtaaac
     7201 tcttagagaa acaaaaagaa gggaagaagc ggatgaaaca aatcggctcc gtcgaagttc
     7261 cgcaagaagc cttcatggcc gttctgaaaa tggatgagca agatagtgtg aaataactta
     7321 taatcaatcg aaaaacctat taaataaacc tttttgagta gatgcaacac tgaggattat
     7381 ctgtataaaa gattttaaac tgtcatttgg ttatcacggc gatactaaaa ttaacaaaat
     7441 tggaatattt ttcttgaaga tttttagctg tcagtatatg atgaaagcat ctcataggag
     7501 gtgctttttt catggttgat aattcaagtg gaagggttct taaatctcta agaaaagaga
     7561 aaaaactatc tcaaaaaaag ttagctgatt tagcaggtat ttcacaaagt actttagtta
     7621 aatatgaaaa agggtcaaga aaaatcccta aagacgtaga taatactcta agcaagattc
     7681 tgaatataga aactctaata aaagatgagg aagataagat tgagattctc atcggtaaac
     7741 taattgcata cagagatatg aataagttac ttaacaaaga gttagctgat aatataggaa
     7801 ttagtgaagt attactcagt tatgtgttaa atagaaagag aaatccgtca aaagaaatgc
     7861 aaaaaaaaat cgatattttt ctattaagta atgaaaaaga aattttgaag gagattaatc
     7921 gtgatagtga gatatttagt ttatcaaaag acgataaaat tgttatggga aaaagaatac
     7981 gagaagtccg aaagaaccgg gaagagacgc ttgaaaaatt tggtaaaaac tttaccatct
     8041 atacaggcaa aaatgttata agtagatggg aaaaaggtat taatattcca gatattgaaa
     8101 aactaatgaa tattgcctat cttggtaagg tcactgttcc ttaccttatg tacggagaag
     8161 attataagaa tatacttcca aaagatgaaa gagttagcga ttttaaaaag ataaattctt
     8221 ttagtatggg attaaggatg aggaaaatta ggaaagatta ttatctagaa agggaggagt
     8281 ttggaaagct tttttctcct tcaatttcaa aatggtccat agataggtat gagaatggta
     8341 gagatatacc caatactaat cgaattatcc aatatgctta tataggaaat ctttctttag
     8401 aatttttgat ttacgggata taaaaatagt ttacgtcgat acttattaag ttatcgacgt
     8461 tttttattat agaaaaaatt tataaaagga ggtttcttga tatgataaga aacaaaaagg
     8521 gtttgttgaa agttgcttta ctggcagctt ttttctaagt aactttttga caagctcaat
     8581 ggcaacacaa gcggaagaag taatacaaga actaactgtt atgaataaca gctagataaa
     8641 atgggctatg tatgttatcc aacaatttag taatcactag aagcctagcg aaagttcgct
     8701 tgataagtta tagatgagta ttgatttgta gtgtttccaa atcaaaaggg tacagagcca
     8761 catgaaatat gttgtcctct gcagcgtcag gatgggaatc cataccatgg agattcggag
     8821 atctgtgagg gaatacttac gtggttaata tgtcagttgt gttggacgta gtaatggtca
     8881 tagtgggtag attgactgaa ttcttatatg agaaaatgaa accaacaaga agatagggtt
     8941 atttatacag aattggggat cttttctgga aaagtaatcg gataatgcga gattcgtacg
     9001 gtctttttta aatttctcta aaaaaaacgg catcgaatgg gttgggtgat tgataagcaa
     9061 tgaatcatag actgatatag aataaaaaat gattctattt atctttttac atctatcgtt
     9121 ttttcaagta gccgcaaatt atatcagcat tcaacaattt ttgtatacaa gttctagtaa
     9181 aaggatctga agaaaaagtt ggttgttgtg aagataaaaa aagaatcagg ttttactgag
     9241 tttttcttca aaatttgtgt tattaggtta ggacaaagat aagaagaagt atgaagattt
     9301 aaaaaaggaa tgaggaaaag atagtaattt ccgattattg gagttttttt atttttcgtt
     9361 tgtcaaatta agttagacaa atcatctttt gtgacgtaac tcaaaaatac ttccattggt
     9421 gtccgatagt gtaatgattt tctaggaata tgatttcgtt tcgatgccac cgattggata
     9481 aaggtttcag atacaccatt aaaatccata gctttataca aaccatcttt acgtaataag
     9541 ccatttgaat gttcattcaa tcctcgttga gaaggtgttc ctggatccgc aaaataaatt
     9601 gaaatatcgt tggtattact aatctttttc caatttgaga attcttttcc acaatcaaat
     9661 gtgatggatt taaataagtt ttttgggaca caacgaaacc attgattcag cctattttca
     9721 atgtctttag cctgtctgcc ttcgggtttc aaggtaatga tgactttaga tagccgttca
     9781 actaatgtga tgaccgcgct tttatgtttt ccacccacga tagtgtcacc ttccaggtga
     9841 ccaaattcat gatcaaactg ggtatagtct gtctttctgt ctcggattga ccggcgaaac
     9901 ccttgttttc ctcttttttc tttatgaccg tttggttttc tttttccctt cattggtaaa
     9961 tcgtgagtgt caaaggtttt atctttaaac attcgataca gtgtgcgtac cgaacaagca
    10021 ataggaaact ctgctcgacc aataaggaca tcaggagccc acccttgaac aacctttttt
    10081 tgaatgtatt cctgttgctc atcaggtaaa acaatcggat gtcttccgca gttacgtttg
    10141 tttttcttat attgtttata gtagctcatt gcgcttccac cagatttaag aaaacgatag
    10201 accttataaa tagtttgtcg agaacgttgt aacagattgg ctacttttga aacaggttgt
    10261 gattgattga aataagcttc tatcattacg agttcagttg gtgtaagatg gttataggtc
    10321 atttgtactc actccttata attctttcgt cggaactatt ttgagtgtag ca
//
LOCUS       DADLIO010000091        10223 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.094, whole genome shotgun sequence.
ACCESSION   DADLIO010000091 DADLIO010000000
VERSION     DADLIO010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10223
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.094"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            388..594
                     /locus_tag="JOX41_002497"
     CDS             388..594
                     /locus_tag="JOX41_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HAY6450195.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(796..1797)
                     /locus_tag="JOX41_002498"
     CDS             complement(796..1797)
                     /locus_tag="JOX41_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAY6450196.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(1802..3715)
                     /locus_tag="JOX41_002499"
     CDS             complement(1802..3715)
                     /locus_tag="JOX41_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HAY6450197.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            complement(3883..4389)
                     /locus_tag="JOX41_002500"
     CDS             complement(3883..4389)
                     /locus_tag="JOX41_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAY6450198.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            4549..4989
                     /locus_tag="JOX41_002501"
     CDS             4549..4989
                     /locus_tag="JOX41_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAY6450199.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            complement(5015..6172)
                     /locus_tag="JOX41_002502"
     CDS             complement(5015..6172)
                     /locus_tag="JOX41_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450200.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6175..6531)
                     /locus_tag="JOX41_002503"
     CDS             complement(6175..6531)
                     /locus_tag="JOX41_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450201.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            complement(6829..7803)
                     /gene="sgrA"
                     /locus_tag="JOX41_002504"
     CDS             complement(6829..7803)
                     /gene="sgrA"
                     /locus_tag="JOX41_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HAY6450202.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            complement(7999..8838)
                     /locus_tag="JOX41_002505"
     CDS             complement(7999..8838)
                     /locus_tag="JOX41_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAY6450203.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            9023..9910
                     /locus_tag="JOX41_002506"
     CDS             9023..9910
                     /locus_tag="JOX41_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rotamase"
                     /protein_id="HAY6450204.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
BASE COUNT         3089 a         2031 c         1532 g         3571 t
ORIGIN      
        1 aattaaaaaa aattttggtg aattaagtat ttccttgata acactggctt ttggcctcat
       61 tttaggttat catttgtaat tttatttcac agttgatatg attgttatgt aaaataaaaa
      121 agtttaggat acatcgaatt tttggggaaa ttcttttggg ggtatcctaa atcttttcta
      181 ttatattccc atattttcta ttattggtct agacgtatga tggtaaactt tgtacctatc
      241 tgattgctga atcattaatt gcttatcatt agccatcttt gtttcaagtt cgctagatga
      301 tcattttatt cacatcctaa caaacttgtc acatttatag attcttaatc tatttatcat
      361 acaattataa aaaaggaggt gctgcttatg aaagctatcc atatttcttt gctttttttc
      421 gctagtgcat tgattttatt tgctattcat ctttgttccc agccttatat caataacaac
      481 ggaatattag tggaaccagc attcttttgc ttaccactcg gctttttgtc ccttcttgcc
      541 tccgcaggct tcggatttgt tgcttttttt aaacgatcaa aacaacaaat ctgacttata
      601 aaatttacgt aaaagagatc gtgacaataa tcgtgtgata ttcccaaatt tcgaataaaa
      661 ggtgcccctt gccatctcta actcctcagt cacaagttac aatattcata aaccatgaaa
      721 agcttgttta ttgaaattgc tccttgtgac ttggagctaa gtgacagatt acaacctctt
      781 ttgcatcata agactttact ccttgaaaaa cattactaac ttttgatatg tttcttgcgc
      841 ttgtttattg ctgaaatcaa actgatattc atggttcaaa acagcatttt tctccgcata
      901 atctactttt gtgactttca cccccgcttt ctcaaataca gaagttactt cttccatttg
      961 tttcgtaaac gtatttgtat ttccatccgt taagaatgtg ttttgcgtcc aacgatccgc
     1021 atgtctgacc aaggctaaac ttttgacctt ctctgattgt tcaaagtcct tattatcaaa
     1081 gtaagcccat ccacattttt cataaagaaa gctagagatt ttatcactta cttgagtaag
     1141 tgcagaagga tccaacagac cagacaaaga aataaacttc gtaatctgct tgttctccaa
     1201 agtcggatca agatgatcag cttttttaat ttcttcattt tgaagtgcta acaaatattc
     1261 tccactaatt tgtgcacctg ccgaatttcc accaatcgaa atattcgacc aatctgcttg
     1321 atcttttatc tcttttttag ctgcttgaat ggcttcgttc aattggataa ctggtgtagg
     1381 atgttttgct tccggtgatc gttcataatc tatatttacg atgatttgct gcgtgtctga
     1441 acatagatat tccaaataat cacgacaatc atttttatcc cctcctacat atgcgcctcc
     1501 atgcatccag aaaagaatcg gtaatttttt cttttccact ttcggtgtgt agatatccat
     1561 attattattt ttgtactttg aaggatagga tatttctttt tttatatcga tttgttcgat
     1621 tttttgctgg aaatcatctg gtcgggcata tacttgttct ttttcacttg tgtcaaattg
     1681 ttttctaaca agcaagctaa tcggctttgg tgtgatttga ttaatcaaaa atacagtgac
     1741 taaaataact acgatgataa ctggtactgc aatcactatt cgcttgaacc atttcattca
     1801 tttaccctct ctttcttcgc caaatccatg tgataatcgt gctaacagat aaaaatccac
     1861 ctgaataaat gagaagcgaa tgtttctttt ctccagtttt cggcaacatt cttttttttg
     1921 catctgtctt tttttgtact ttcactgtca tctgaatcgg ttgcgtatca tcacttgatt
     1981 gatcctctcg aggttcattc tttcccttat tgtctgcatt ctctgtcgga tcttgctttt
     2041 ttggtggagc tactgggatt tttttgtaat agaaaataat agttggtatc gtctcattaa
     2101 aaatcccttc agtcggtcct tcaacatttg ctaattcgta tccttcgaat gtcttttgct
     2161 ctgtcatata attttctcca taagctccgt aaagctggat ttcgtcctgg tctttgagta
     2221 gacttttatt gttttcatcc acatacttta cgtttatctg atcatggaac actactttca
     2281 aaaagtccgt tacatgtttc gtgtaggcag catggtcaac ttcctgtgcc tttccatgcc
     2341 ctgctccttc tactaataaa agatctttat accctcctga taactcatat aatttttgcg
     2401 cgttagacac aggtactaca tcatctgctg ttccatggat aatcaattta ggcaatgaat
     2461 ctgacattcc aatcgtaggt agagcagctt ttgtatccaa atgcatctcc tgatcaaaat
     2521 agtattgttt caaaaggccc ataaataaat cttcatgctc ttgatcccca atgatgtcta
     2581 actgattttt tatggcatcc ggtagtgcgg gggctactgt ctggctgtac gtaaaacgta
     2641 gttgttcatc aattgatgca aatccgcaat tttcaataat tcctttgaca ttgacaggaa
     2701 tatctttcgc taatacagac atcatcgtag ctgctcccat cgaaccacca taaagtaaaa
     2761 tcttttgaga tggccgctct cgaacttctt gatttatcca gtaaaggacg tcatctgact
     2821 catattgtcc ataggtcaca taatcgcctc cgctattacc agtcgctctg gaatcaacaa
     2881 ataataaatt atacccggcc ttataaaaat cattgtattc ttctgtaacg atcccgttat
     2941 tccaattccc tcgaaatccg ccatggatca tgactgtttt atctgaacct tgatcgacat
     3001 aatatgcata tacatccatc attttgccat cttgtttgtt tagtacagtt tgatgaagtt
     3061 gttttgtatt tggatagaag cctgtgtttt ctgtaggcgt tgtcccatca tctgtacctc
     3121 caagcatcga catcaacaca ctgttttttg caaaagcgat atcgtacaat agataagtag
     3181 caatcagatg tttgataatc tctttatcta caccataatc attaacagca agctcagtga
     3241 ctaataactc tattaatttt gacttgatgt cttctgttgg tccattaagt atttctgtca
     3301 tctgtttacc gaagtaattc aaatattctt taccattgaa attttcacct ttaccgatat
     3361 catcattttc tgtcccattc tctttgtcac ttactttagc agaagaggat tcgtcgtttg
     3421 acatttttgt agctgttgct tcttctgttt gttggttatc tgtggtagcg gtcgtttctt
     3481 gatctgtgct agtaacagat gtctcaaccg ttgtttcagt atttgtttct gtttgtgaag
     3541 tactcgattt cgtttcattt ccagcatcag tagtttctgt ggtttctacc tcccgagatt
     3601 ccgattcgga agaaatgctc tctccatata ctgtccattg cgggacgctt gtacttacag
     3661 caaataagat gaccaacgct ccctttaata cttgttttgt tctcaagcta ttcactcctt
     3721 tttatgtttc taggagaatt atatgtaaac gcaaacattt tttatacaaa aaataaatgg
     3781 tttatcccat aaaaatagaa caggattatt ttctcatttt acgtaataaa gcagaatgga
     3841 taaaccagta tccattctgc tttttttaaa cgaagaaaca acttattgct ccaaaaatgt
     3901 cagaaatcgt ttatcccaaa ttttctcgta aaaagcgatt gtttcctttg ctttcataaa
     3961 aggattatca taagttgtcg ttgctcctct acacatcata agctggtatc ctaatccatg
     4021 agcaaacttc acagtcgtat ctatacaata ctctgcttgt gccccacata attcgatcga
     4081 atgacagtcc aattcagtta ataaaacact caaattagtc ttataaaatg aattcgcatg
     4141 ggtttttctc acaaaataac tgtgctcagg aatagataat tccgacaata gctcccatgg
     4201 ttttgtttgt ggcactaatt gagcatcttc gtgttgaacg aaaataactg gtttcccaat
     4261 cgtttcgtat gttttgattc ttttattcac taatgctgtc actgtttcta attcgtgtat
     4321 cggcgaagaa tcaaaacata cccctttttg taaatcgatc actactattg cgtcggctgt
     4381 gtttgacata cttgtgcctt ctttcttttt tcttgattta atagtatttc ttatctagct
     4441 agttccatta tacgtgacaa cattttctta ttttacacct ctaaatggca cttttcgact
     4501 atttcttcat gttattattt cataaatact tagctattgg aggaatgtat gatgattaaa
     4561 ttgtatacag gttctggctg ctcgtcttca agacgcgcaa aacgttggct tatcgtccat
     4621 gatataccgt ttatcgaaca gaacttaatt cgtcaaccac taaccaaaaa tgaatttatc
     4681 cacttactaa aattgacaaa caacggcgtg accgaaatgc tctctactca ttctattagt
     4741 tataaaaatc ttgttcacag aatagatgaa ctcagtttga gtgaactata tattgagatt
     4801 cgtacatccc cttctttatt gaaaaaaccg attatctacg accaatctgc aaaacttttg
     4861 actggattta gcgaagataa aatcaggatg ttcctttcta aaactaaaag aaagcaagag
     4921 ctcaacgaac tcttgctttc tggtcatctt gtcgatttta aagaaaataa tctttttgca
     4981 atgtcttaat tttggcataa acaatctgct tttcttaatt aacgaaatcc aatttttcca
     5041 atatggatct atttttctca ttcctgattt ttatgatttc agctttcaga cgcgcccaat
     5101 cattttttgt aggttgtcca ttccagtaaa atatctgtgt attcgtttga tcatatgcct
     5161 ttttgtcgat aggataatcg ctaatgacaa tatcaggtaa ctgatcagcg gatgcactat
     5221 attttattgg gcgttcagtc atagataata tccttttctt tgcccataat tcctgtgttt
     5281 taccatactt tgattgaata tagaatatga caggttgttc gtgttttata aaaatatccc
     5341 tgactaacat acagtattga aaaatcaacc gtctgttctt ttcataataa gtattaagct
     5401 ctggaattct gcgagctacc ccactaaaaa actgttgcat gattggatac atcactggaa
     5461 atatatgctg aaaatctctg tcttctgctg attttccaaa agcatccacc ttcttttttg
     5521 tcccaaaaac ccttgaatac aaatggatca ttgccaaatt gacatataga taattttttt
     5581 ctgaagttgt aaaacaaatc ttgaagtttt tttcaaaatt ttctacaata gacgattcaa
     5641 tccagcccca actttcttgt actttatctg gagtatccaa caaatcttct tccaaatagg
     5701 tgttcattac accaaacata aaataaaggt aagcttgctc tgttggagtg atgtgattca
     5761 tcgaccagaa gtttgcttca aaaaaaggct ctagtatgta atgcgtaaac tcttcttttg
     5821 ttatcaatgg atgcacaaat ttgttcatct cttctgggac atacgtaatc gagtggcctt
     5881 gtttcattcg ttgcaacgaa attcttagta ggctgatcca tttctttcta tctatactac
     5941 gcgtatatgg cgcatgtttc gcaaattttt ctaatagttg acgtttattt tttatacttg
     6001 ataatatatc agaatgattt tcgtcgaatg actgccaata catcaagtga aaaaagtatc
     6061 ggatacggta ttcttctcct tctatcggat tacctttttt caagctgcaa gataaatgat
     6121 agtttttcaa aatagtatta agttctctta attttctttg aatcgtacgc aaacttatat
     6181 aattttttga ctaagatttt ctaaggattg ataagtacct ttgtaaagtg aatccagtaa
     6241 aatataacca atcgttccct ctaaaagtat agaataaact ttactcagta aaaactgaga
     6301 agaaaactcg acttttatca tcttgttttc tgaaagaaaa gataatttat attctggata
     6361 cctttcgcaa aacgattctg cttgttgaat caccgaattc atcttagcca gggtgtagtt
     6421 tagatctaaa gcgatatcct tcaccacata taatttctcg tctctttcat aacaatagtt
     6481 caaaaattga tatacttgcc tttcattgat atcaataaat tcttcaaaca aagtacatac
     6541 tcctttttat ctattattta gacttattcc gacagctaca tgaataacgt acaaatagat
     6601 tcgttactga tttttcagag atactaccat gcgcagtgtg cattgtcaat tattcttgct
     6661 cttattttcc atttgtgttc ctgttatttc ctgtttctca aatatgttag taaacaaaaa
     6721 tagatctggc aaagctacaa cttcgccagg caatacagca ctctcgaatg aaatattcac
     6781 tcaaaaatct atcgttttat tcaattttag atctgttgct tttattcttt atttcactcg
     6841 atggaagaga gaacgaaaat agcttgctcc tacaatcaaa atgagtaaca cacccatcca
     6901 tgtaattagc ttgttcaagg ttctactacc agtttctggt aaatcgcttt ttctattatc
     6961 tgtttctttc gctttttctt gatgatcaat tccacgagaa acaaaatcag gctgttttag
     7021 cacacttttt aggttgctcc ctgcatttct cttttgttcc ttagttggta tgataggtac
     7081 caaatcaagt tcattattta cttttcctgt gctgctttcg ctgctcgtgc ttcctgtgct
     7141 actctcacta ctcatgcttc ctgtgctact ttcactactc gtactctccg tactgctttc
     7201 gctgctcgtg cttcctgtgc tactttcact actcgtactc tccgtactgc tttcgctgct
     7261 cgtgttttct gtgctacttt cactgctcgt actctctgta ctgctttcac cgctcgtgtt
     7321 ttctgtactg ctttcactac ttgtgctatc cgtactgctt ggcggtccaa caactgtcca
     7381 actgcttggt ttcaaattct ccgtgatcgt catctgtcca tcataaaaaa caatcaaatc
     7441 aactttatct ttactcttga tctcatcaat cgatagttct gcagaaatca ttattgtata
     7501 ctcaatacca gcggtccatt gtacgtcttt taaataaact tccccaataa ctttttctga
     7561 acttccatta ccatcccaac catatgttag aacagcatgt acatcactag cattcacgct
     7621 tttgtttggt ttgactggaa tagtaatgac ttgttgtgtc atgtcataaa caatccgatc
     7681 agttttcaca gtaaatgaaa gattctcatt tgcccgttca tttgcagaag tactgattcc
     7741 aatcattgct gcaattatac tcagcccaag aataacaaat aatacggtcg ctgttttctt
     7801 catttctatc actctccata taattacctt ctatttgata aaggaattat ataaaatgaa
     7861 aatgatgaga acacgacagt cagttgtgaa aatctaacaa aagatgtcgt gtattcgctt
     7921 gaatttgttt actttttcgt ttaatcaatg acagacttaa aaaagcaaga ccgatatcag
     7981 ccttgctttc ttcatctttt attgataaac agcagtgtat ttcttcatcc gctttgtttt
     8041 atatgcatag agtaacaaac caacaatcaa gactaacaag aataatgtag ttgatataga
     8101 tgcttcagcc ccaaagtttc ccccagtaat tattgtattt tgcgattgga tcagagtgga
     8161 gaaaaaacct tgttcttgcg ttccgctgac tggtataccc aaaatagctc cttgtgtcca
     8221 attccaagta atatgagcac caatagccgt aaataaactt cctgtactgt agataagtgc
     8281 gctgaaaaag caacctgcta aaaagatatt gaaaactgcc agaaatgtca tgttaggatt
     8341 caatccgtgc aaaagagcaa ataatgcagc agatccaatc attgctatta acggaccaaa
     8401 tctaagcatc tgatgctgaa aaaagccacg gaataaaagc tcttctgatg cccccactgc
     8461 aataaataaa ataaaactcg ttatcagcgg cacaatgttt gcgtttcctg aatctaaccg
     8521 atacgccccc gtcaaatata atggactagt aataagcaga aacactccaa ttccaacaac
     8581 gagacctccc gctaaatacc cccagtcttt tcctcgaaca gaaacaccat aatcttctat
     8641 tctttttcct tcgaccttac tagcaagaaa taaagctagt aaaaaaacag ctaaatgtcc
     8701 gaccgtaccg gcaattgctc caatccattc actatttcca ataaacatat ccgcaagtgc
     8761 attattgaca agaattccta aaacaaaacc aactaagact attaaaacag atccaatcaa
     8821 ccgaataatc ctgatcatct ttcatccctc ctttatatta agtttaacaa cccttttctt
     8881 tcttgtctcg tgaaaactat gtaaatgttc tccatcatag agagaataga tttttacgaa
     8941 ctaagaatat ctacagcaac cttacgaaaa tgaaagactg tctccctaat tcttctgtta
     9001 gactgttttt aataaggaaa ggatgggaaa ttttttgaaa aaacaactac taattatgtg
     9061 cctttcagca tgtgcaattt tactattctc aggttgtagc aagtccaatg aaacgattgc
     9121 aacgtttaaa ggtggaacac ttacagttca ggatttttat gataacccaa aagttaaatc
     9181 aaataatcaa acactattaa aaaaaatgat tgtcttcaaa gcatttgatg atgtatacgg
     9241 aaaagagatt tcttcaaagg aagtaacaaa agaatataat gaacaaatca aaaaactcgg
     9301 tccaaactac aaggaacaat taaaagcagt tggccaaaca gaagagacat ataagaaact
     9361 ctttaaacag atgctggctt tccaatacgg tttgaaagcc aatgtaaaat taacagataa
     9421 agatctagac actgcttgga aagaattcta tccagaagtt agtacacaga tcattctatt
     9481 ttcgactaaa gaagaagcag ataaagcaaa aaaagaagca aatgaaggag aaaatttctc
     9541 caagcttgtt caagcttatg gaaaaaataa aacattaaag gaaactgatg gaaaaatgaa
     9601 ttttgattca accaatccag agattcctac tgaagtaaaa aaagcagcat ttaaactaaa
     9661 aaacggggaa gtttctgata tcattcctgt aacagatcca acgacttatc agcaaagcta
     9721 ttatctagta aaaatggtaa aaaaacagga taaaggttct aataaagaca aatacaaatc
     9781 tgagctagaa aaaattgcta ccgaagcaaa aactcttgat acggaattca tggataaaac
     9841 aatccgtaaa gtgatgaaaa aagacaatgt aactattaaa gatccttatg taaaaaatat
     9901 attcaaataa acaaatttga cccaattggg gatgtggcaa aatttgagaa gtgatttttg
     9961 gaaattcctt cttatttttg aggcaaacca cttttgccac aacttcatcg gggccttttt
    10021 ttatttgtac caaaacaaat cactggattt gttacaatca tgaggatata atttaaaaaa
    10081 gttttttatt tctatcacat gaatcaatgc gccattaagt agattctttc atgcttccct
    10141 attttttcac ttgccgtatc gcttcaaaaa caactatcat aaactcaaac tcgactgaaa
    10201 agttatttta aaaaagacta aaa
//
LOCUS       DADLIO010000092         9954 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.095, whole genome shotgun sequence.
ACCESSION   DADLIO010000092 DADLIO010000000
VERSION     DADLIO010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9954
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.095"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            253..732
                     /locus_tag="JOX41_002507"
     CDS             253..732
                     /locus_tag="JOX41_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450205.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNMDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            765..2993
                     /locus_tag="JOX41_002508"
     CDS             765..2993
                     /locus_tag="JOX41_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAY6450206.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKERTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            3122..4765
                     /locus_tag="JOX41_002509"
     CDS             3122..4765
                     /locus_tag="JOX41_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HAY6450207.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKHALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(4838..5383)
                     /locus_tag="JOX41_002510"
     CDS             complement(4838..5383)
                     /locus_tag="JOX41_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HAY6450208.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(5406..5891)
                     /locus_tag="JOX41_002511"
     CDS             complement(5406..5891)
                     /locus_tag="JOX41_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAY6450209.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(5881..6693)
                     /locus_tag="JOX41_002512"
     CDS             complement(5881..6693)
                     /locus_tag="JOX41_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HAY6450210.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(6832..8364)
                     /locus_tag="JOX41_002513"
     CDS             complement(6832..8364)
                     /locus_tag="JOX41_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HAY6450211.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIPILYLMEQPALSVSQSFLD
                     KNEISYMTHTSGTTGIPKLICHSAHSMGWRTKWQKTVFTKISEKKLIAFHISPVHSRF
                     NIGISSLMSMGFPMMPLANAQSSKVVHMLEAHRPIALETHPNNFVQWRFTAKEHPEAF
                     SGIRYYHSTFDAINNQTMKTFLRTSMAQDAVFLQVYGQSECGPMILKAHTLESLKTSD
                     ARDMGVGLEDMTSARITDSVGNVLPENTDGHIQLLSKGRALTYYKEDARFQENVYGDW
                     WDSGDYGFMDKHGHLFLKDRQVDLIETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSP
                     QPIIALAPDKEMDWNRWWEQVHELPRLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQ
                     KS"
     gene            complement(8473..9504)
                     /locus_tag="JOX41_002514"
     CDS             complement(8473..9504)
                     /locus_tag="JOX41_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAY6450212.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
BASE COUNT         3317 a         1844 c         1915 g         2878 t
ORIGIN      
        1 caaaaaagat gttggtgaag ttcaccaaca tcaaaaagta tagagccaaa atattccaac
       61 atcatcttgg actttctaca tgttactaat gagcgtgtaa aagaacgaga tggtgttttt
      121 atttctatca atgaagctct ttttctttgc aatcctcact tcaatcctct ataatgtcgc
      181 atatagttta gtaaatgagt aaactactaa tttacttatt tactaaaaat aaaaggatga
      241 ggagttaaaa taatggaaat accaacaaat ttaaaacata aaccagtaat cgttgtagaa
      301 gactatgata aagttgatgg aagaaatgca ttaaatatgg atgcaaaagg gctttcactg
      361 ggccttgctc agtggaatga tcgtggaaaa gtcgatatct caggcaaggt atggcgacat
      421 actggagaaa aatggtcacg acagtcggaa gaattaccaa tcacacgtat tttagattta
      481 gcgatcttag ctgcgcaagg aagtttatac ttccaagatg cttatcgtta tgaaaaattt
      541 tatgatccag aaaatccagt cgtagacatc attggattac aagggaaccg aatgacggta
      601 gaagtagata ccaaaaatcc aaagatcgat gaagacatca ttttgtatta cgatacacta
      661 caaaaagacg gagaactgat tggggaacga ttccgtattt taaaacgtct tttagatgag
      721 ctaggatatt aatagacaga gatgatcaaa aggggaagag aagcatggag aatttctcac
      781 taacagaaaa ccgaaccttt tcacggctag aaaagcaaat gatctggaag aaaccgaaaa
      841 gccatcggac aagtgcagaa gaatggcgga tcgcctccga aatcaaaggg aattggcaag
      901 atcctgaaat gaaaatcagt aacgtacttt tggaaggaga tgccgggtcg gggaagacac
      961 aattagccaa agcactatct gctgatctgc aacttcccta tacaaaagtg acctgttttg
     1021 cagatatgga caaatcagat gttttcggag ccttattacc tgtagtagat tctaataagg
     1081 aacaagacca agaattacta gaagctattt accaaacaga tacacttgaa gctgtactga
     1141 cactgatcca gaaccattac ggcattgatc ctttttctgc taaagaaaaa ttagcagagc
     1201 tagttcaaag gatcgaagct gattatccag atgcaatcca ttacagctat tacccttctg
     1261 aaatcgttcg agcgattgaa aaaggctatt tattagagat tcaagagccg actgtcatcc
     1321 gagatgcctc tgttcttgtg gcacttaact cagcgctcga accaaatggg atgttgaatt
     1381 taccgacagg aatcattcgt cgccatccag attgcgtcat tgtgatcact acaaatcgaa
     1441 attaccaagg aaatcgccca ttaaatgaat ctttaagaga tcggatgcaa catgcggaaa
     1501 aaatggatct tcctgcctta gaagtcatgg cagaacgtgc gatggcgaaa actatgatcc
     1561 aaaaacaaga acttctctta aagatggcag agattatccg tttgttggat gaaactgcaa
     1621 aagctaacgc catcaaaggt gtagcaggaa tgcgttctta tttttattgg gcaaatacct
     1681 ataagcaagg acaagattta ctccagtcga tttatccaaa agttttgtat aaattatcca
     1741 ctgattcaga tgaattggca attcttgaac aagctttgtc tgacagtgga ttgctactgg
     1801 aacttcagga catattgaga aaagaaaaat ggggtcatcc tcaatctgag catacaaaag
     1861 aaagaaccat tagcgccgaa gaagcaaatg aacgaaacat cactgaaaat gctgaagaaa
     1921 ttctgcgctt agatgaaaag aaatcgttgt ctgctgaaga accaaatgag ggagaagaga
     1981 aacaagaaga aacaatagaa aaaaacgaga ttcctcctca aatgcaaaaa gaacgcagta
     2041 gcgatatcga aggaaaaaat caaaaagaac aacaaacagg agatgattct caagaaatgt
     2101 ctgcttctga catggaagca catgataagg aaatcaagaa gcaactgaat aaagaagcgc
     2161 gacaaatcat gaaggaaacg attcatgaaa aagaaggtct catcgttcac cgaccagctt
     2221 tccaaggaaa aacgccggaa gcacgtgagc tacacatgca agtaatgcca atagtagaat
     2281 cacttagccg gcaaatttta gagttactgg ataatgaaca aacagagacg taccaaaaag
     2341 gaaaatacga aggtcagcgg ttcaatgcaa gcaaagtagc atatggtgat ttgagaaatt
     2401 ttgacaaaaa gaacccgcca catgagcaac cttctttagc ggtagctgta cggatcgatg
     2461 aatctgggtc aatgatacgg gatgatcgga tcgaagcggc aaaaaaagca gcgattgcca
     2521 ttgccgaatt ttctaagaaa gtcgatatcc cattgttgat ttacggagat acagcagacc
     2581 gttcgtcaag agaaaagact tctttgtttt cttataaaga atttgaagac ggatttcaat
     2641 ggttaaatga aaaattagtc actatgaaac caaggcaaaa caatcgtgat ggtgctgcac
     2701 ttcgtttagc agcagaaaaa ttaaacagac aatccgcaac aaccaaactg ttgcttaata
     2761 ttagtgacgg tcagccaaaa gcgttgccgg attatacagg caaaaaagca aaagaagata
     2821 tccagtctgt tttgaaagaa tatgaacgtc aaggaatcct atttgtctcc gcagctattg
     2881 gccaagacaa agaagaaatc aagtcgatct acggtgaaag tcgttttgta gatattactg
     2941 acttgaatga atttcccaag caaatgattc aactgattgc ccgctatcta tgataaaata
     3001 aagctcaacg aacgcactta gcagattcgt tgagcttttc gtttctagtt accggtaaca
     3061 aggatacttc taaaatagaa tcggttataa tcaagaggga ccgttaaagg agtgaaacga
     3121 tatgatacaa gaacaaaaat ggtggaaaga agcagtaggc tatcaaatct atcctgctag
     3181 tttcaaagat agcaatggcg atggtcaagg agacatcaat gggatccgtg aaaaacttaa
     3241 ttatttgaaa gatcttggta tcggctttat ctggatcaat ccgatctatc aatctccatt
     3301 tgtcgataat ggttatgacg taagtgacta tcaagatata gaagagagat tcggaacgat
     3361 ggaagatttt gatttattgc taaaagaagc acatgaatta gggatcaaag tgattatgga
     3421 tcttgtcatc aaccatagtt cggatcagca tcaatggttt gaagaatcga aaaaatctaa
     3481 agaaagcccg tatcgcgatt attacatttg ggtcgacggg gtagatggca aagaaccgaa
     3541 taattggaca tcgattttcg gcggttctgc ttgggagtat tctcatgaaa ctggacagta
     3601 ttatctgcat gtttttgcaa aagaacaacc agacttaaat tgggaaagcg agaaattgaa
     3661 agaagaacta ttcaatatga tccgatggtg gttggataaa gggatagatg gatttcgttt
     3721 agatgcgatt tctcatgtaa aaaaagatga atattcagta aaagccacag agaacccttt
     3781 ctcacccttt caaaatgtct caggaatcga agaacatttg accgatttga aacatgtttt
     3841 tgaagagtac gatatcatga ctgtcggaga agcaagtggt gtcactgcag aagaaggacc
     3901 acaatgggta gggaaagacg gttatttcga tatgatattc gaatttgatc atatccatat
     3961 ctggcagcaa gaaaaagaag ggcaattaga tgtccttaaa ttgaaacatg cattaagcgc
     4021 ttggcaaact tcattggatg gtatcggatg gaacgcttta tatatggaaa accatgatgt
     4081 tcctcgtgcc gtttcagtgt ttggagatac tcgtcccgat ttttgggcta tgtctgcaaa
     4141 agcaatcgct atgatgtatt tctttttgca aggtacgcca tttatttatc aaggacagga
     4201 aatcggaatg acgaatatgc cctttgaatc gatcgatcaa gttgatgcag tagattcgaa
     4261 aagactttat aaaaggctgc ttgcggaagg taagacaaga gaagaagcat tggatatcat
     4321 tcgtgaaaca acgagagaca acagcaggac acccatgcaa tggacttcgg aacaatatgc
     4381 tggtttttct acacatgaac cttggctgat cactaatcca aataccaaaa cgatcaatgt
     4441 agaacaacaa gaatatgaac cagagtcggt cctgcaattc tataagaaca tgatccgcat
     4501 tagacaaacc aataaaggtc tgatatacgg ttcttataaa gaatatcttc atgaacatcc
     4561 acaactttat gtctatgaaa gatatttaga agatgaacaa tatcttatta tggtaaactt
     4621 aacagaatca cttgctgact atgaacttcc aaaagaagca gatcagtcct ggacattact
     4681 cttgtcaaat tcctctagcg gagaatttga agctaaaggc atactagcac cttatgaagc
     4741 tcggttatat aaaacaaaca agtaaaactt cctcgttaaa gttcattagt tggactttgc
     4801 gaggaagttt ttcagattgc tctgtcaatt actcatttca ataattcgct ctaggaccac
     4861 cgatatattt aggacgagag cgaagggctg tcacgtgagc ttgtccaagg gttttcaaac
     4921 gaggtctgac aggtacttgg acatgcttga tatgcatacc gattgatgtg tcaccgatat
     4981 cgataccggc ttgtccaact acgtgttcca cttcgacagg atcattgaac tggtcaaaag
     5041 cagcaacaga acaagcacct ccagcatgta gtgcaggaac aacagagaca atttcgaaat
     5101 tttttgcttc tgccactgtt cgttctacta ctaatgctcg gttcaaatgt tcacaacctt
     5161 ggacagctag cgcaatttct ttaggatcca acaactcttt taacgtacgg atgatccatt
     5221 gaccaacttc cgcactggaa ttttttccaa tatgtcctcc aacgacttcg cttgtgctgc
     5281 atcctaaaac aaaaagatca ccttttttca agtgtgcctc agccaatatg tcattaacta
     5341 tttcagtcaa ttggtctttt aattcttttt ctgacaactt cattttctaa aaccttcttt
     5401 ttcaattaat attgcttccg tgcttgaata cgttgaagac ttgcagttat aggaaaggca
     5461 agtcccattc caatcagatt ttggaagatg tttcctggta tagaagccac tccagccggc
     5521 caatcatata aaatccaacc ggcgatacca tagccgatga tcataactaa gcttcctaat
     5581 aaaagcccta atccccacat acgagtagaa gatttgctga aagaaccagc aacatatcct
     5641 tgtaacccgt ggatcactaa tgaaaaaact gcccactgcg gatatcctga aatcaaatcg
     5701 atcaatagac cactggaagc accaacaact aatccacccg ttggaccata aagaaaagca
     5761 gcggtataga tcccggcctc gcataatgtc acaaatccat tcgtagccgg tacagggatc
     5821 aaaattgtta atgaaagggc aactgtcaac gcaatcagca tagcatagat cgttaattgc
     5881 ttagttttca tttctcattc ctcctttttg aataccgcca gaccagacac ttccggtatg
     5941 atcgttcatc agcacgccat tagaaataca atgggcaaca aattttttac tttctgctac
     6001 tgctttggta aaatctgccc ctaacacaag attcgctgtt attgcagaag aaaaggcaca
     6061 accggccccg tttactgttg tagtgtcgat ttttttatga gaaaatacct cataatgatc
     6121 aattgaatag agaagatcca cagcttcatc tccagccatc cttgtgccgc ctttgatcac
     6181 aatgtttttt gttcctgaag cagtgagttc tttagcgaga tggatcattt ctgttaacga
     6241 agagggaaga gcttgaccag aaagtaaagc agcttctgcc aaattaggcg taatcatcgt
     6301 aacaagtgga aaaagttctt cgatgagctg cgaaatatac aattgattga tcacagcttc
     6361 agtttctttg aatgccaaaa cagggtctaa aatgattggg atattttgtt ttgtttttat
     6421 gaagtctcga acaaccatga ttgcttcact tgaattcaat aacccaattt tgataccatc
     6481 taatgaagtc attttatcaa tcgaaactaa ctgtcgttta agcaattcca aagatataga
     6541 ttccagcata aatcgctcat taatatctag tgcccctata gaagtcaagg cgcttagtcc
     6601 gaatagacca aaattctcaa aagtttttaa atctgtttgg attcctccac cagcaaatgg
     6661 atcagaaccg ccaattgtca agattctttt cataacattt tcctccatga ataagagtat
     6721 aacgaaattt tcaaaaaaga aaaacagcca attggcatat ttttatctca tccaatttaa
     6781 aaaaacaaaa agaaaagaaa gaccaaaatg gatctttctt tccttaaata gttaggactt
     6841 ttgtgatttt aattctttct cgatttgaag ccgttgcact ttcattgtag ctgttcgcgg
     6901 gattgcatca aaatcacgga tgatagggac gttcaagcga ggaagttcat ggacttgctc
     6961 ccaccatcga ttccaatcca tttctttatc aggagctaaa gcaataatcg gttgtggaga
     7021 atgattttta tcccttacaa tcactacttc tgccaaaaaa tctaacgaat ctaataaaaa
     7081 gtcttcaata gctaatgtac tattgatcgt ttcgatcaaa tccacttgcc gatctttcaa
     7141 aaataggtgg ccatgcttat ccataaaacc gtaatctccg ctatcccacc aatcgccata
     7201 aacattttcc tggaaccgtg catcttcctt gtaataagtc aaagcccgtc ctttagacag
     7261 taattgtata tgaccatctg tgttttcagg taggacattc ccaactgaat ctgtaatccg
     7321 agcgcttgtc atgtcttcca gtccaacgcc catatctctt gcatcacttg ttttcaaact
     7381 ctctagtgta tgagccttaa gaatcattgg tccgcattca ctttggccat atacttgaag
     7441 aaataccgca tcctgtgcca tcgacgttcg caaaaatgtc ttcattgtct ggttgtttat
     7501 agcatcaaaa gtggagtgat agtatcggat acccgaaaaa gcttctggat gctccttagc
     7561 agtaaaacgc cactgaacaa agttattcgg atgggtctct agtgcaattg gccggtgagc
     7621 ttccaacata tgaacaactt ttgaactttg tgcgtttgct aaaggcatca taggaaatcc
     7681 catggacatc aaagaagaga taccaatatt gaatctggaa tgcactggag agatgtgaaa
     7741 agcgattaat ttcttttccg aaatttttgt gaaaactgtt ttttgccatt tcgtccgcca
     7801 tcccatagaa tgagcagaat gacaaataag tttagggata ccagttgtac cagaagtatg
     7861 ggtcatataa gaaatttcat ttttgtctaa aaatgattga gaaacagaca aagcaggttg
     7921 ttccattaaa taaagaatag gaatctgttt tgattttgtt ccatttgaaa tttctctcac
     7981 tcgctttttt gtctcatcat caaataaaat gaaagggtct tctaaacgat cgataaatac
     8041 ttccattgtt gttgttggta gatgataaga agtcatgaca ggcactgcac caaggtaaga
     8101 cacagaaaca gctagaaggt atgtgtcaaa agcggaactc ttataaataa taactttgtc
     8161 tccggatttc actccaagat gagccaattg ataagcccgt ttcaacacac tttcgcagca
     8221 ttttttgtaa gttgtttcaa gtcctaattc tgggaaagct gaaagtggct catcaaagat
     8281 aatcggggtc tcggaaaagt tagctgcagc ttcttgaaaa ttcgtaaata agttcaaagg
     8341 ggaatacgtt atggtctcca tcattcacac tccattatct tttgttaagt aatatacaaa
     8401 ttcaagataa tcgtaacata atcctttata taataacata gtttattgtg aaaaaaagat
     8461 catacatttg ttttatatgg aagaaacccg aacgaatgcc gctaattcgt gataagaaaa
     8521 atcaaccatc ttttcccaga tatcttgaaa agaatgggat gagaggtatc gattaccaca
     8581 taaataattt accgcgtcag catcatctaa atatagttct gcataataac gatatgtttt
     8641 tctgcatagt tctggcgata cgtttttata tactgtaatt ttgctcaaaa tttggcgaat
     8701 agtccgagga gaaatttgct gatcatgtga ggaacgaaaa acaaaagaat tttcgtccgt
     8761 attttgtgct gttaacttaa aatagttctc cagaaatggc atcgcttctt ttggtattgg
     8821 tactttattc agtctgtttt cttttctatt cagattaaga atctgcttgg tcaaagatac
     8881 atctttacgt ttaagttcta ctacttcatg gatctttaat ccgcaataca gaagaatggc
     8941 agtaattgca aggttcctcg gtctattctt ttcttcaaag ctagcttctc tgcttgtttg
     9001 aaagccttca atcgggataa acaaatgctc aaaatctttg aaaagttctg catcgatata
     9061 tcgcggagct gctttggttg tttccggtaa acttgtaccc aaaagagaaa tctcttcttc
     9121 aatcagtcct ttttgataca aaaatcgtaa aaaatgattt aatgaatatt gcttccttga
     9181 aatcccgtaa tagctatttt caaacaattg ctccgtttct tggttcgctg tagtttggaa
     9241 cgaacgagta tgtcgataga ttttagctaa gaaattctga taatcttgtt tttctaaatg
     9301 gataatcagc tgatcatcca cttcttcaga aaatactttt ctcaaataat cagtaaacag
     9361 atgaaaatct tttgcgtatt catagcgact gcctaatgaa agggaagaac gattttcttc
     9421 taaaaactgt tgaaagacgg aagggagcaa gtgtgtacgt tgctttaact tttcttgcag
     9481 ttgttttcta gttttgctgt ccattacaaa ttccctccaa tagtgttcat tttctatatt
     9541 ttaccgcatt tcatcaaatg aagatagaca gtttgtcttg atcttaggaa gcaaattttt
     9601 aactaagtac tagctaaaag atatgaagta agaagataca tttttagtta ttttattagt
     9661 gcagtcattc ttttgatctt ttaattgatt tatcctcttt ttagctatgt ggttacttca
     9721 tgagcaatga aatggatttg gttcgttcta atggcaggag gctctttctt ttatttccga
     9781 aaaattagaa aacatttttt cagaatcgat tggctctcca tttattcaat aatggtttgt
     9841 ctaacgatat tgttgggata attcttaaag aagtattaga aatagttggt acttcattac
     9901 tttacatgaa gatttattct atggtaggag caattatatt gagaattaat cctt
//
LOCUS       DADLIO010000093         9811 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.096, whole genome shotgun sequence.
ACCESSION   DADLIO010000093 DADLIO010000000
VERSION     DADLIO010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9811
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.096"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(34..2154)
                     /locus_tag="JOX41_002515"
     CDS             complement(34..2154)
                     /locus_tag="JOX41_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAY6450213.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYISAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2384..3562
                     /locus_tag="JOX41_002516"
     CDS             2384..3562
                     /locus_tag="JOX41_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HAY6450214.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3578..4336
                     /gene="aroD"
                     /locus_tag="JOX41_002517"
     CDS             3578..4336
                     /gene="aroD"
                     /locus_tag="JOX41_002517"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HAY6450215.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFFSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4359..4844
                     /gene="ybaK"
                     /locus_tag="JOX41_002518"
     CDS             4359..4844
                     /gene="ybaK"
                     /locus_tag="JOX41_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HAY6450216.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4915..6168)
                     /locus_tag="JOX41_002519"
     CDS             complement(4915..6168)
                     /locus_tag="JOX41_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAY6450217.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6285..7634
                     /gene="gdhA"
                     /locus_tag="JOX41_002520"
     CDS             6285..7634
                     /gene="gdhA"
                     /locus_tag="JOX41_002520"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HAY6450218.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7746..9092
                     /locus_tag="JOX41_002521"
     CDS             7746..9092
                     /locus_tag="JOX41_002521"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HAY6450219.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9400..9786)
                     /locus_tag="JOX41_002522"
     CDS             complement(9400..9786)
                     /locus_tag="JOX41_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAY6450220.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         3128 a         1782 c         2009 g         2892 t
ORIGIN      
        1 aattttgtcg ctgctccttt taaatttatt ttatcattcg gaagaacttg tggtcgttcc
       61 gtgaagttct tggtacgttt gcgttttata aagatcaaca gttgattgtc cgttgtgttc
      121 actaaagaca ctagttgact tgtcaccaag agatttttca gcttctttta atttctctaa
      181 gccattcttg tagtcataat cactggtatc aattgggtct aatccactat tcgtatagaa
      241 ccgaagaaga tcaccattat tgatttggtc agaaacagct aactgtttat caactttttc
      301 tttcagtgaa tcaatttcat tctgtacttc ctcagtaggt tcagtaatag cttcaccagt
      361 ttcgttacta tagatcgtac caccgtagta agtatatttt ggtgtaacaa aatcaccatc
      421 acggaaagaa acaagctgtt catgatcttt cgagaataga tcttgtccta actgaatata
      481 attttttgta tctacaccta gtaagtgaag taatgtaggc aaggcatcaa cttgtccgcc
      541 gtaagtgtga ttgattccgc cctgtgtttg tccagggata tggatcatat aagggacacg
      601 ctgcatttgt gcattgtcgt agtttgtcca agtagaactt gtttttccaa ctaattcagc
      661 tagattttta tttcttgaat tcgagacacc gtaatggtca ccgtaaagga cgatgactga
      721 attatcatac aagccgcttt ctttcaaata attgaagaat tcttgtacgg cggtatctaa
      781 ataattggct gtcgcaaagt aaccgttgat cgtttcatca tttgtattgg ctaacgggaa
      841 tcctgcttcg tcattggtga attttgaata aggataatgg ttagatacag caatgaattt
      901 tgaataaaat ggttgttgca gacgttccaa gtattgtacg gattgttgga aaaatggttt
      961 atcatgcaac ccgtattgga acgaattgtc atcattaaca tcataataag aagaatcaaa
     1021 gaaataatca tatcctaaat tcttgtatgt ctcgtttcga ttccagaatg taccagcgtt
     1081 cccatggaat accgcactaa tgtaaccttg tgtttgactt aaaatatcag gtgcagcttg
     1141 gaaagtattt tttccgccta attgtgtgaa caaggagcct tgattcaagc caaacaatga
     1201 attttccatc agcgtttccg catcgcttgt ttttcctgct tttacttgat ggaaaaagtt
     1261 gtcaaaactg aacgtgctgt tgctgtggta aagactattg atgaaaggtg taacttcatg
     1321 ctggagacca ttctcatctg tcaatttata atcgatcagg aattgctgga agctttctaa
     1381 atggatataa atcacatttt ttcctctagc gagcccgaac aaatcgtcat ttggtgctgc
     1441 ataatgttct tttacataat tttctacttc tttcatatca ttgggacttg cttctgcccg
     1501 cacttggttt gtctggtaag tttgaacacc gtcataaacc atgaaagcat tcaagccaag
     1561 atatttgacc aaataatcac gagagaatgt tcgagtcagc aattctggac gatcagcttc
     1621 cgccataaaa agatttcctg agaaaatcat aactgctaat gtagagatcg caaaagccat
     1681 tcttgctcgg atcgggcgag ggtccaactt gatttttttt gcaatcagca gaacagtcaa
     1741 gataataaaa tcgatccaat agatcacatc atatgggcga aacagtcgaa tggcactttc
     1801 tcccagacca ctcgctactt tcccagcacc taaaatcgtg ttgatcgtaa tgaagtccgt
     1861 gaattctcga taataagtga cattcgaaaa aacaagcaat gtcaaaagaa aataaatgac
     1921 catcatcgtg atataagcaa ctctagggcg tctgatataa agagcaattc caagtaataa
     1981 caatgtagtt gcaatagggt tgataaacaa gataaagtat tgaatgccac tttcgattcc
     2041 gagatggaaa tcaactaaat aggcaaaaat cgttttcaac caaagtaaaa cgactagtaa
     2101 agaaaaaaat ccgagcctct tattcaaaaa ggcaggtgtt tttatacatt tcaagataat
     2161 cttcctttct gcacttctta atcacagaag tgtcctgaaa ccatgttaca cagctcactt
     2221 attctcattt attttactag tatgacaata tagtgtcaat tgaaaccaga agtttatgct
     2281 gtttcattaa ggttttcttt aagcttcatg aaaaaatgag cagtaagaca agtcctatgt
     2341 tttttgttat acttgggaag agaaagctaa agcaggtgaa ggaatgaaag taaaagtaaa
     2401 aaaaagagca agcaatcgat tgaaaaaagg atatccactg atccaaaaag aagaccttgc
     2461 tcatccccaa aaagaaacca cgcaatgggt ggaattagtt gattcgcaaa accaatttat
     2521 cgcaaaagga tatctaggaa agcagaataa gggaatcggt tgggtattga gccagcagaa
     2581 catcccattt gatcaatctt tttttgaaga attttttgtg aagtcaaaag aaaaaagaac
     2641 tttctttttt tcagatgatt ctactaccgc ttttcgtata ttcaatggag aaggagacgg
     2701 gatcggcggt ctgattgttg attattatgc aggttatgct gttttttctt ggtataacga
     2761 aacgttatat gcacatcgtg aattattgat tcaagctttt cgtgaaatct acccggaaat
     2821 cataggaggc tatgagaaaa ttcgatttga atcagtaaat ctgcctgaga gccagttcat
     2881 ttacggaaaa gaggcaccgg aacccttgat cgtaaaagaa aacggagtaa aatttgccgt
     2941 ttatttaaat gaaggattaa tgactgggat ctttttagac caaaaagaag tacggggatc
     3001 attagcagaa ggtttcgctt ctgggaaaac agttttgaac atgtttagtt ataccggcgc
     3061 cttttctgtt gctgccgcaa tgggaggggc aatcgaaaca acaagtgtcg atctagcaaa
     3121 acgcagttta aaaaaaacac aggaacagtt tgaagtgaat ggtttggatg tcgatcagca
     3181 aaaaatcatt gttatggacg tattcgagta tttcaaatac gccaaaagaa aacaattttt
     3241 atatgacatg attgtattgg atccaccaag ttttgccaga aataagaaaa aagtctttcg
     3301 cgtagcaaaa gattatgggg aactggtcaa ggatagtctg gatattttag cagaagacgg
     3361 gatacttatt gcgtctacaa atgctgcgaa tgtctcgata gaacaattcc aaacaatgat
     3421 tgaagaggaa ttccatgcca aaaatgtttc ttttgaacaa cttgctttat atcgtctgcc
     3481 aaaagatttc cagacgacgg ataccttttt agaaggcaat tatctgaaag tgtttgttta
     3541 tcaaattaaa aataaccatt agaaggagcg atgcagaatg gttcgggtaa agggattgaa
     3601 tataggaagc ggtagaccaa agatttgtgc gcctcttatc ggggccgtcc gagaggaagt
     3661 attacgtgaa gcagttcttg cacgtgaagc aggggccgat ttagtcgaat ggcgagtcga
     3721 tcattatcgt gaagtttttt cttttgatga agtagcagaa acattggttc ttatccatga
     3781 gatgcttgat ggactgccgt tattatttac gtttcgtacc ttagctgaag gcggagaaca
     3841 agacatatcg atccgtcagt atcgcgacct ttatgaacat gtgatacaca caggattagt
     3901 agatatggtc gatatcgagt tgttcaaagt agaaagtcta ggaaaaagac tgatagagga
     3961 aatcaagtct ttaaacattc ctttaattat cagtagtcat gattttaaag aaacaccagc
     4021 agaccctgtc ttgctttacc gattgaatgt tatggaacat tttggagccg atatcggaaa
     4081 actggcagta actcccaata atgaacgaga tgttttgcgg ttgatggagt tgactagacg
     4141 ggcaaatgct tttttctcca tgcctattat tacgatgtcc atgggaaatc ttggtaaaat
     4201 ttctcgtctg gttggcggaa cgacgggttc cgttatgaca tttggttcct taagcagcga
     4261 ttctacttct gctccaggac aattaccggt caaagcattg aagcaaatta ttcaattatt
     4321 aaatgaaccg ttgtagaaca agtttgaggt gatatttttt ggcaaagaaa aaaatagtaa
     4381 aaacgaatgc aatccgtatg gtcgaacaaa aaaagattcc ctatacagag cacgaatatg
     4441 agtgggacga aagccaccta agtgcgtcat cggtcgctga acagcttcca gaaagccaat
     4501 ctcgtatatt taaaacactg gttgctgtgg gcaatgtgac ggggcctctt gttgctgtga
     4561 taccgggaga agccgaattg aatctaaaaa aattagcaaa agtttcaggg aataaaaaag
     4621 tagaaatgct ccatttaaaa gatttggaag caacgaccgg atacatacgt ggtggctgct
     4681 cgcctatagg tatgaaaaaa ctatttccta cttatttaga tcaaattgca gaaagctatg
     4741 aacaaatcat tgtctcggct ggcagaagag ggctacagat ggagttagca cctcaagata
     4801 tctgtgcatt aacgagcgga caatttgcag atataaaaca ataaatcata cgtataaaag
     4861 aaagaaggag gccgggatgt tgtttgtcca gtctccttct ttctttttta tacattatgc
     4921 tctttgcccg gcattcattc ctgctacatg ccctgtagcg aaagccgctg tgatattaaa
     4981 gccgccagta taaccattga catccagtaa ttctcccgca aaatacagac catcaatgat
     5041 tttactctcc aatgttttag gataaatttc ctttagagaa acccctccgc cagttacaaa
     5101 tgatttctca ataggaaaag ttttgttgat tgatagctta aactctttgc atagttgaac
     5161 aaaatcttga atttgttttt gagaggcttg ttgtcctgtc agatgatcca tttcaagccg
     5221 ctcaagaaag aaaactaaca atcgctcagg caatatacca tgccaagcat tgaccaagtt
     5281 ctttttggtt gctttacttt tttctgtcaa tatatgaata agctcttgtt tggtttgtgt
     5341 agggaaacaa tccagagaaa gtgtcactgg ttctcccgtt ttctctaatt ctttattgac
     5401 aaaacttgaa caacgcagtg cagccggacc agaaataccg aaatgggtga aaagtaaatc
     5461 catcgtatgt tcagtcaata cacgaccttt tttatttaaa acgcgtaaag tgatgtcttg
     5521 taaagaaagc ccttgaagtg ttttctcctg aatatacggt tcatccgata tcaaggggga
     5581 ctctgtcgca taaagaggcg tcaccgtgtg acccactcgc ttcacgatct tgtacccatc
     5641 tccagtagaa ccagtagatg gataagtccg tccaccagtt gttaagataa tggcaggagc
     5701 atggaactct tcgaattccg tgcgtatacc gtaaatttta tgttctttgt ggatcaattt
     5761 ctctactcga gtagagaata gaagcgtcac atctagttct ttcagacgat tgagcaatgc
     5821 ttcgataatc gtttttgatt tatttgttac aggaaacatc cgtccatgat cctcttcttt
     5881 taaatgtacg ccttgtgatt caaagaagtt catgatatcg aaattattcc attgcgcaaa
     5941 cgtactatat aaaaactttc catttccagg aatatgtgca atcaaatcat caacaggacg
     6001 attgttcgta acattgcacc gaccaccacc tgtcatcagt agtttttttc ctgctttttt
     6061 gtttttttcg atcaagagta cgcgtgcgcc ttgttcagct gcactgatcg ctgccatcat
     6121 cccgcttgtt ccagcgccga ctacgatcac atcatacagt ttttccattc cctcacctca
     6181 aggaaagtgt agcatatctg aagaaagaaa acagaaaaaa atgttttgag ccaaaagaga
     6241 aaatgagcta aaatgaggga agataagcaa aggagcgtgg aacgatgaca aacgcaacag
     6301 aatatgttca agcaattcaa gaaaagctac atcaaaagga tcaagggcaa gaagaatttt
     6361 tacaagcaat cgatgaattc atgcccacgg ttatgtcttt tttggacact catcccgaat
     6421 atatcgaaaa gaatatctta gaacttttaa cggaaccaga aagagttatt caatttcgag
     6481 tgccttggca agatgatgaa ggaaactggc gagtaaatag agggtaccgt atccaataca
     6541 actcagctat cggcccttat aaaggtggat tgcgcttcca tcctagtgtc aatctaagta
     6601 tcttgaaatt tttggctttt gaacagattt tcaagaatag tttaaccggt ctgccaatcg
     6661 gtggaggaaa aggcggaagt gacttcgatc ctaaaggaaa atctgataat gagatcatgc
     6721 gtttttgtca aagtttcatg ctggaattgt caaaacatat cggcccatcg attgatgttc
     6781 ctgcgggaga tatcggtgta ggagctagag aaatcggcta tttgttcggc gaatataaac
     6841 gattgaaaaa atatgatact ggtgtgttga caggtaaacc tttggatttt tggggaagta
     6901 agatacgtac ggaagctact ggttatggat tagtgtatta tgtcaaacat ctattgaacg
     6961 aagaaaaaga ttcatttaat caaaaaacag tttttgtttc cggaagcggg aatgtagcca
     7021 tttatgcaat cgaaaaagtg caagagctag gcgggaaagt tgttacatgt tcagattcta
     7081 gcgggtacat ctatgatcca gaaggaatag atgtgaaact attgaaagaa gtcaaagaaa
     7141 tcaatagaca acgtttgacg gaatacgcaa accaacgtcc ttctgctatt tatcatgctg
     7201 gagaatctgt ttggacattg aaagaaaaag cggatatcgc tttgccatgt gctactcaaa
     7261 atgaaataga cgaaagcttg gccgaaatct tagtagaaaa tgggatcaaa atcgtagcag
     7321 aaggcgctaa tatgccatgt acagtaaaag ctgtttctgt tcttcatgaa gcaggcgtgt
     7381 ggtattgtcc aggaaaagct gctaatgctg gaggagtagc agtatctgct ttagaaatga
     7441 gtcagaacgt ccagcgattg acttgggaaa gagagcaagt ggatgagcag ctggatcaaa
     7501 tcatggaaac gatttaccat acgtgtcgcc aaacagcagc cgagtacggc gacgaaaaaa
     7561 atctgcttct tggagcaaat gttgctggat ttgaaaaagt tgccaaagca atggcagcag
     7621 aaggtttagt ttgaaaaatg aaactttctt ggaaatattg tcagcatttt gtttatttgc
     7681 ttgaaaaata ataaaaaaaa acgtaaagta ttacctgtag agtaaaccta taaggaggag
     7741 aacaaatggc acacattcat tttgactatt caaaagtagc accgtttgtc aacgaacaag
     7801 agttagggta catgcaaagc caagtaacag cagcccacaa cgaattacgg gaaggtactg
     7861 gcgcaggaag cgacttccgc ggctggatcg atttaccaac gaactatgac aaagaagaat
     7921 ttgcacgtat caaagaagca gctaaaaaaa tccaatctga ttctgaagta ttagttgtta
     7981 tcggtatcgg tggttcttat ttaggcgctc gtgcagcgat cgacttcttg aatcacacat
     8041 tcttcaattt attagatagc aacacaagaa aagcaccaca aatcttcttt gccggaaatt
     8101 caatcagctc aacatatatt gctgacttga tcgaagtaat cggtgatcgc gacttttcag
     8161 taaacgttat ttcaaaatct ggaacaacta ctgaaccagc gattgcgttc cgtgtattca
     8221 aagagcttct tgttaagaaa tatggacaag aagaagcaaa caaacgtatc tacgctacaa
     8281 cagataaagc aaaaggtgca gttaaagtag aagcagatgc agaaggttgg gaaactttcg
     8341 tgattcctga tgacatcggc ggacgtttct ctgtattaac tgctgttggt ttgttaccaa
     8401 tcgctgttag tggtgcagat atcgatgcat tgatgcaagg tgccgctgat gcaagcaaag
     8461 catactcaag cgacaaacta gaagaaaacg aagcttacca atacgcagca atgcgcaaca
     8521 ttctttaccg taaaggcaaa gtaactgagt tgttgatcaa ctatgaacca ggaatgcaat
     8581 acttctcaga atggtggaaa caattgtatg gtgaatctga aggaaaagac caaaaaggca
     8641 tctatccttc aagcgcaaac ttctcaactg atttgcactc tttaggacaa ttcatccaag
     8701 aaggacgtcg caatattttt gaaacagttg tgaaggttga aaaacctcgt aaatcaatca
     8761 caattcctga acaagcagaa gatttagacg gtctaggcta cttgcaagga aaagaagtgg
     8821 acttcgtaaa tacaaaagca tttgaaggaa cattgcttgc tcatacagac ggtgacgtgc
     8881 ctaacttgct agtcaaaatt ccagaaatgg atgcttatac attgggttat acaatgtact
     8941 tctttgaaat tgctgtaggt atttcaggtt acttgaatgg aatcaaccca ttcgaccaac
     9001 caggtgtaga agcttacaag aaaaacatgt tcgcacttct aggcaaacca ggctttgaag
     9061 atcttgctaa agaattgaac gaacgcctgt aagataaggg tttttcgcta gatttaaata
     9121 atcagtgata gaaacatgtt cgctttaaaa tgaaaactgg tacccattta ggtactcaaa
     9181 catactgcat cgtttattca gaataagggg ctgtgacaag acgtttgtca cagtcccttg
     9241 tttgtataga aatcgattga ttgccttgct ctttagtttg ttttaggact ttaagaacag
     9301 tgaggctgac ttcgaaggtt aattctgttt ttttgttttc tagaatcagt aagcaaaaaa
     9361 gcactcactt cgagtgcttt tttgcgatat attcttagct taagataggc ctaatttttc
     9421 ttttacagat gagggtacct tatcgctggt aattactttt ttctctatga tccgcttttc
     9481 gcttgctttc aactgcaaga tcgttccttc ggggtaagca gaaccattgg cagagtcacc
     9541 agaagtaatg acatcgaaat ctaactgtct tttttcaccg ttttcagcat aagcatctac
     9601 gttgtattta aaacctcttc caattacttc cccattatct gctttgatat cagtttctgc
     9661 aggcattgga gctttgacta ccgcataata atctttacct acataagtag actgatagta
     9721 gtcccaacct ttccatccta taaaagcaat caatatgata acgatcaacc ctaaaatttt
     9781 tttcatgaaa gatctccttt tttattttta t
//
LOCUS       DADLIO010000094         9593 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.097, whole genome shotgun sequence.
ACCESSION   DADLIO010000094 DADLIO010000000
VERSION     DADLIO010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9593
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.097"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(<1..641)
                     /locus_tag="JOX41_002523"
     CDS             complement(<1..641)
                     /locus_tag="JOX41_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HAY6450221.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQT"
     gene            complement(643..1407)
                     /locus_tag="JOX41_002524"
     CDS             complement(643..1407)
                     /locus_tag="JOX41_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HAY6450222.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(1415..2092)
                     /locus_tag="JOX41_002525"
     CDS             complement(1415..2092)
                     /locus_tag="JOX41_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HAY6450223.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(2129..3514)
                     /locus_tag="JOX41_002526"
     CDS             complement(2129..3514)
                     /locus_tag="JOX41_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HAY6450224.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(3724..3808)
                     /gene="ffs"
                     /locus_tag="JOX41_002527"
     ncRNA           complement(3724..3808)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="JOX41_002527"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(3831..4346)
                     /gene="tadA"
                     /locus_tag="JOX41_002528"
     CDS             complement(3831..4346)
                     /gene="tadA"
                     /locus_tag="JOX41_002528"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HAY6450225.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            4453..5310
                     /locus_tag="JOX41_002529"
     CDS             4453..5310
                     /locus_tag="JOX41_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HAY6450226.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYRYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(5391..5726)
                     /locus_tag="JOX41_002530"
     CDS             complement(5391..5726)
                     /locus_tag="JOX41_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450227.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(5793..7163)
                     /locus_tag="JOX41_002531"
     CDS             complement(5793..7163)
                     /locus_tag="JOX41_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NOL1/NOP2/sun family putative RNA methylase"
                     /protein_id="HAY6450228.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(7241..7777)
                     /locus_tag="JOX41_002532"
     CDS             complement(7241..7777)
                     /locus_tag="JOX41_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAY6450229.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            8086..9567
                     /locus_tag="JOX41_002533"
     CDS             8086..9567
                     /locus_tag="JOX41_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAY6450230.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
BASE COUNT         2908 a         1969 c         1502 g         3214 t
ORIGIN      
        1 tttgtttgtt tcaagctatt ttttcctaag aaaagaaaaa cagcaaaaaa taattctaat
       61 aatacaaaaa ataagataaa gctatgcatg aaaaattctt ctggaagtac attgatgatt
      121 ggatcagtaa cgggatcgaa taaccagtca tcgttgttga aaaacgtttc atgaaaaagg
      181 ataaaaaagc gatcaaatcc tatcatcatg aaaaaaccga aaacaactgg cagtaacatg
      241 ccgatttgaa acggacgaat caaccgccaa agccgatcat tcttttgcaa atatttgata
      301 aacaaaatac tcgggatcaa agtgatgaaa aacacagcat aatccactaa aaacaaaatt
      361 ttcacttcat aaaagtgatg ggctccgcta gcagaaactg ggaaatctgg caagctgagg
      421 atggttttga agggattatt gagataattc attaggtgat caaaattttt cagtaacgtc
      481 tcttgatcta aagaagtata atccaaaatt tgcaaatgtc cgatatcaaa tacgtatagt
      541 ggtcgaaagt tgatcgtcac accaactgcc agactgatca gtgtcagaaa taggctgaac
      601 aatccagcat attccatcca ctgccatctc gaatttttca tattagaagc tccattcatc
      661 cagtgattgt ttcacatagg tagctgggat aggcaaccca ggtacatctt cttcttttgt
      721 aaaacctgat aaaacgagca aagtatctat attattgcgt atcccagctt ggatatctgt
      781 ttcatagtta tctccaacca tgattacttc ttctttttgc agccctaata cttcaacggc
      841 tttatccata atgatggctt ctggttttcc gatgtagatc ggcggcgttt gggttgctgt
      901 ctctacaaaa gagatgactg accctgctcc aggaagaagg ccgcgttcag taggtatatt
      961 cttatctggg ttcgttccaa tgaaagtagc acctttttga atagcaagtg ttgctttaac
     1021 tactttttca taggtcagat aattatctaa gcctaccact acatagtcag gagcctcttc
     1081 ttcccatgta aatccggcag ctaaaatcaa gtcaatcaat cctgcttctc cgataacata
     1141 gacttttttc ccttttccat ctgctttcat aaaatcgatt gttgccaaag tagctgtgta
     1201 gactgtctct ggagctacat gaatgtcaaa ctcatctgct agacgattag ctactgtttc
     1261 tggtgactta gtcgtgttat tggtaacaaa caagaaaggt aattttcttt tttgcaattc
     1321 ttccacaaat cgtttaccgg ccggtatggg ttgtgtccca cgataaatcg ttccgtctaa
     1381 atcaattaaa tatcctttat agtccattca tccactactc ttcccttttt ctgatcgtaa
     1441 atgctgtttt tgttttttct acttgtttag gttgttcttg tttttttact ttttcagagg
     1501 tttttgctga ctctgttttt cgatttttaa taaccggttt tttgcgatta gatgcgactg
     1561 gtcctttttt ctcatcgata tacgcacgat tatggttttt tttctttttt cggcgctgag
     1621 ttgtcttttc ttttttaccg ccgattctct cgatgacaaa atacgcacaa ccaaaattgc
     1681 aatattcgta aagatagtct tccaaggaat cgattcgctg atctggatgc gcccgtcgat
     1741 tatccgcttg gaaaaatcct tttaggcgta gttgttcata accccaatct cctacgatat
     1801 aatcatatcg ggctagtaca tcactgtaac gttctccaag cttttctgca ttaaatcctt
     1861 cacgataatc ggacacaagc cgataatgtc tttcacctat caaaaaatta ctgtcatcta
     1921 acagtgtcac tagctcgcct ttgacttttt ctgctttagg ctcctcaacg atttcttcca
     1981 aagcagctgt cagttcttcg gtgactgttg tttcctgttc agctgatgat tttttcttag
     2041 caatttctgt tttatgctca acgttctgct gttcattttg ttttgcagac atgcgttcac
     2101 cacctatctt ttttattata ccttgttttt atttgattgg gtagtgagct ttcaagtaat
     2161 ctcctaccac acttcggata aattcaggga acaaaaattc attttttcca gcaatctcaa
     2221 tcgttggaaa aaatggaaca aacatcaaat gatctacggt agtaaaagta taatttttat
     2281 tcagatcgat tggcttgttc ttccaaaaga cttgatggtt aatagaatca tatgtgattc
     2341 cattatagac catctgccca aaaatcttac cgcgaaatcc cattcccttc ataggatagt
     2401 tacgtaaaaa gttacgattt ttttctattt ctaaaactaa gcggatcaga tcatttccac
     2461 ccaatgtgac atttaacaag tgcatcggat gcggcaacgc agtgtgaagc tgatcctgat
     2521 tgacccgccc ttttggaatt tcagttaaaa acagaccact gtttaatatt gctgcttccg
     2581 tctttcctcg ttctttcacc gcctcaaagg ctacttggat aaacgaatgc tcattgaaga
     2641 tatctagact cagagaaaat ggcaaatctg ctacttcttt ttcttttaat aattcatgcc
     2701 cacgttctag ataactattt atttcttgtt catcttctgt aaaagctgtc attgtttcgg
     2761 tagggatggc tttggctgaa tgcttaagga tttttttctc ttcatcgatg gttaaatgga
     2821 cttcaccgac atactgcccg tactttccag cggctgctat ttggacatca ttgattacgt
     2881 gaccttctct gaataaatga tgggtgtgcg atcctaaaat aacatcaatt gctggtattt
     2941 cttttgcaat ttggaaatca tcctgaatcc cgagatgact catcaaaact aaaacatcca
     3001 cttgtgaacg taaatcttcg actaattctg gcaaaatatc ataaggattc cgtatgtccc
     3061 agccattcgg attataagta agcggaaatg gagcagtaaa tgcaattagt ccgattttcg
     3121 tctggtgttt cgttgtaatg attttatatg gtttcgtcca tgccggtggc tggagcgtat
     3181 ttttatcgaa taagttatcc aggatgatat caaactcagc atgatcgtat aaatgattca
     3241 actcttcttt ggaatttcct acgccttcat tgtttcctat cgtcgctgca tcataaccaa
     3301 cttcattcat cagcaagata ttttcctgtc cattcgttgc ttctgacaat ggatgccaac
     3361 gatccacaaa atcacctaga tctactgcaa tcgttgtcgt tttttctttc ttttcgtttt
     3421 ctcgtttacg ttgatccaaa aaccttctga tccttggcca attttctaaa tgagaatgca
     3481 gatcattcgt atgtaaaatc actatttttt ccatgtaccc tctcgcctct ctttatcttt
     3541 atcataccat aggcagcttt ttcttccatt gaaacaagct ctatttcaga gtttttcctg
     3601 ccttgaagca aattgtataa gtacaatatt cgataaatca gtctggctaa aaaatcagga
     3661 acattcattt ttacagtact ataaaaataa aaaaaacaga cccgaaagtc tgttgtcgtt
     3721 tcattataat cagacacatg gcggaacctg cttagtgctg cttccttcca gacctgacac
     3781 gcttcacaag cccaccattg tcctagcctt tcggcaaaga atagtatacc ttatttttca
     3841 ttcgttgacc agtctttttt taatttcttt tttcgctggc ggagctttcg gaaaaagtca
     3901 gtcaaaatca tcccacattc gtcttctaaa atgccacctt ctacatatgc ttggtggtta
     3961 aaccgctcgt cctccaaaag attcatcaag gtaccggctg ttccgccttt tggatcatac
     4021 gcgccgaaat aaacttctgc tacacgagac aaaatcatcg cgccgctgca cataggacaa
     4081 ggctctaagg taacaaaaag tgcagcatct tccaagcgcc agcttcccac tttttcacag
     4141 gcttccttga ttgcaagcat ttctgcatgt gtagtagcat cttgcgtggt ttctctaagg
     4201 ttatatcctc ttccaatcac ttttccatcc aatacaacca ctgctccaat cggaacttca
     4261 tgaagcattt ctgctttctt tgcttctgcc aatgcaaggc gcatccattt ttctttttct
     4321 actgcatcaa gatttgtatt taccaattac ccttccctgc ctttgttttt tcttgtttta
     4381 ctttagcata tgataaaaag gctgtaacta actttttttt ctatggtaaa ataaatacaa
     4441 gaggtgaaca agatgaaaat ggataaatta cttgctcttt acccacaagc acagaaaaaa
     4501 aactctccag catcagaagc ggatatcctt tcttttgcaa ttgatgatgc ttttatctgg
     4561 atcaaacaag attcattatc tcaacaagaa accagccttt tgaaagcgtt attccctgta
     4621 atcaacgatc aaaaaaaaca cccatggtat cgctatcttt ttaaagatgc ttcttgtgtt
     4681 caagaaaaaa gctttcgttt gatccagctt cacgtcgaat caaaaggaga attcttaaaa
     4741 aaagaatggc aagatactat tttggaatta tttcgctatt ctgctgattt ctttttttat
     4801 acagacacag atgcgctctt agtcgaacaa ataaaccgtg attatcttga tgctactgaa
     4861 atcaacggta tttttctatc tttagatgct gattttgata cgacaacgtc tgtattcgtt
     4921 ggttctttcc attcacctgg caccgacctc gtccctttgt ttgctgaaga aagaaaaatt
     4981 tttttaacag agcaaaacaa tctttatact cacagccgta ctttttctat gcaagatgtg
     5041 gctttacatt actatacaaa agatactgta aaagatagta agttgatcaa aagttacata
     5101 gaactgatca aacaaaatga aatggaagtg atcattcaag aattatggaa tgaattaggc
     5161 aatgtcagct ctgctgcaaa aacactgttt cttcatcgta atactctaaa atatcgaatc
     5221 gaaaaatttc aagaacagtc tggtttcaat ctaaaaaaag ccaacgattt actgttttgc
     5281 tatcttttat tgcttcatga acataattaa agatagatta aaggggttgt gacaataatt
     5341 ttgtcacaac cccttatttc gaatgaatag tgttcaaaag ctagtttctc ttacatcatt
     5401 ttttcaacaa aatgcattag ccggtctttt acatcttcgg ttgaatcttt gattgaatca
     5461 ccataaacag agattttctt ttttcctgat ttgatttttg ctaacattcc catcaaagaa
     5521 tccaagtcac tatctgaaag accatctacg atttctagta atttttcatt tccatcaaat
     5581 ttgtcataga cgaatttttt tactttcgtc cgagtagtca tatgatggat cttttccatt
     5641 acttttcccg atacaacgac tgctgtcgct acactggcag cggctgctac gcttaatccg
     5701 attgttactt ttgttgatgt tttcataagt atcagctcct ttttatctat ctccatcata
     5761 gcatagacaa aaaaataaac gaactaatcc actcagtgaa atctcaatcc tttagggaaa
     5821 aagttcttta ctgttccttt tacttgtttc ccaaatccga caggtatctt atctaatact
     5881 agcaaaaccc atccttgatt cccatcacgt tgaaatgttt ctcctgctgt gtaagattgc
     5941 cattcctttt gagtgatcgg caagcaaggt atattctcta tcttttttgt agcaagcgct
     6001 aatgcatagc taggttcaaa tcgattcttt ttgaaatctc ctaaatgcaa acctgtacgt
     6061 acgactttta aaccatcgag agaaggggct aactcaggaa cttcccaaag atggtcgttg
     6121 aacactaaaa gtcttccagt agcttcataa tgaaaatcat ttgaaaactc cgtccagagt
     6181 ttttcctgct cttttgtcat ttgcacttta cttttttttc gtgtcttctt ttctttatgc
     6241 atctgatttt gtccatgaaa agtcagcttt gcaacaaaat gtccttcacc ctgatcttta
     6301 tgaggccata tacgtattgt tttttccaaa ccagctacgc ttccccattc agaacgtcct
     6361 gaactaacgg attgagtcaa aggaatctcc tcaatcgtta ctggataatt ttctacaagc
     6421 cagctaatga tctcttcatt ttcttctggt gcaaacgtac aagtcgaata aatcagttgt
     6481 cctttatttt ttagcatttt tattgctgaa gacaaaatct cttgctgacg tttttgacag
     6541 tatagcggag attcttctgt ccactctttt attgcatttg gatcttttcg gaacattcct
     6601 tctcctgaac aaggagcatc aaccacgatc cgatcaaaaa agcccgaaaa atgagggaca
     6661 agttctgcgg gtgcatgatt tgtcactatt gcgttcgaaa ctccccatcg ttctatattt
     6721 tctgataaaa tcttcgcacg tttcggaaag atctcattcg tcactaataa ccctttcccc
     6781 ttcatttgag cagctaattg ggttgattta ccaccgggag ccgcacacaa atccaaaact
     6841 ttttcaccgg gttttgctgc agcagctgtt ccaacgatca ttgcacttgg ttcttggcta
     6901 tattcatacc cagcttgatg gaggaaagac tttccattga cagtgccaag aaatccctca
     6961 ttgctgtagg gagcgggttg taattcttcg ctatggtaag tttggaccat gtccaatcct
     7021 gccggtttta gtggattcca ccgaaatcct tttttcacgc ttccttgttc aagcgcagaa
     7081 aaaaaatcgg atgcttcttc gcctaaaaga agacgatatt ttttgataaa ttgctgtggt
     7141 aacgttgtcg cttcctcctt cattccaatg tttcgttaga cattttacaa tcttttttac
     7201 gaaaaataaa ggtggctgat ctactttttc atgttgctgc ctaaggtgac tgttccttta
     7261 agatattttc caagtattca tccgtcacct cgtttttatc ccaaacagcg ttcatcattt
     7321 caagaaaatc ttgagaagaa tcatctgagc gcaaacttcc caatgcatta agccatacca
     7381 attcaagcga cttttcttct ttgatcttcg tgtgaccttt gacatatgag aaaaatggcc
     7441 gcttaaatag cgaatccatg tctaaatcag attttgcaat gatttcacga atactttcat
     7501 ggatagaaaa aaaatctttc aataagtaga caatgcttaa aacatcatcg gaactgcatt
     7561 cagctaagta gttttcaaaa taaacagtga tttcttctaa tatcttctct tttaacccgc
     7621 tgattgattt gaaatgtgta taaatcgggt atgtagaaca accgcagaac tctgctaact
     7681 ctcttgcagt aattgacttc attccatatt cttccacgta taccatactt ttgaacagca
     7741 aatattcttt actataattt gttactctcc ccatcattct tacctccgtc tcttttcatc
     7801 tacccataaa taaataacat aaataattct aaaaatatta ttgataatta tcaaaacata
     7861 tttagttata tccattaaaa atcaattttt ccgccttaaa aacaagaata tcttgacaaa
     7921 ataccctagg aaataaacaa tagaataaac aaggtaacaa aaaaattaaa taacgttata
     7981 taaaaaagaa ggcgacactc tgtgagaata acacagactg aaatgacttt ccactcacag
     8041 tttttgtcta actatataca aaaacagaat aaaaaggagg tatttatgct aattgaagca
     8101 agaaaaaaag agttacttgt tctacaaatg gtcattcaaa aaaataattg ttctttacaa
     8161 gaattatcca atgacttaca tattccaaaa cggacaatca aagaactgat ccgaaaaata
     8221 aatgtatcac tcaagcaatt tttattgatt gatgaattta tttattctaa tcataaagga
     8281 gagatccaaa ccaaagaaac cgatcaaact aaaaagttag ctgttttttc taagttaaaa
     8341 ttatgctacc taaaagaatc caatcgtttt aactatttga tgttactaat caattatcca
     8401 caaactgctg taccaaaaaa atatttactt gaacaacttt atatatcgcc ctcctatctc
     8461 gaaaaactga caaaacagct caatcattcc ttaaaaaaat tccatttacg gatcctatct
     8521 gtaaaaaatt gctgtactct tgaaggaaat gagttatcta tccgtctcta tctttacttt
     8581 tttctttcag atacatttgg aggtaacgat tggccatttt cctcacttga attaaatgca
     8641 ctaaaaatga acagtacaga tgagcaaata gaaaaaattt caaaacaaga aaaaaatatc
     8701 tacttgctgt taactttatt catattacga aacaaacaac aggcatattt tccaaaaact
     8761 tcttctgaaa tcactgaatt gatggactta ttgcagcata cacatgatta ttcagaatac
     8821 tttacttctt tttcagtgag tcgcccttgt gaagagacag aaacagagag agcctacttt
     8881 aattattttt tctattgttt ttttccaaat caaatctctt ttcgacaaaa acaggagatt
     8941 ggttttttat tttccacaag caaaaacctt atttgtcgac aagtcggtca attgatgact
     9001 tacttaactc aacagtttcc tctcaaccat ttagaaaata aaataccaat ttatttttat
     9061 tttcttgtgt tggcagttgt ttttttcgaa ctgttgggtg aatccagcag tagtttttct
     9121 acactttgct ttccagaagc cacgtccaat cattctagtt cttttataca ggaaaagaaa
     9181 ttaagagaaa aaatcgatac aattttttca aaaaatgggg aaagaaacca aatcagtcaa
     9241 taccttagtc aattgatcca acacttacta caaacagaaa cgaaagagca gttactcatc
     9301 catttgcaga taaccaaaca gtttacagga aattatcatc ttcaaagcca tttgcagcag
     9361 ttatttcgca aagatgctgt taaaattacc gcatattcag aacatgctga tttgatcatt
     9421 acagatcagc atgagaaaat ttcagatgaa acggagactt tctatctgga tacaacgcac
     9481 aatacagtgt tatttggcaa gttaataaaa gcggttcatg aactgtatat gaaaaaaggt
     9541 tatgagaaca aaacaaagag gatgtgacaa aattcttgtc acatcctctt att
//
LOCUS       DADLIO010000095         9509 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.098, whole genome shotgun sequence.
ACCESSION   DADLIO010000095 DADLIO010000000
VERSION     DADLIO010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9509
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.098"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            <1..757
                     /locus_tag="JOX41_002534"
     CDS             <1..757
                     /locus_tag="JOX41_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAY6450231.1"
                     /translation="SFIMMDGQSHALLDIVENRRLPYLECYFSRFSLATREAVQWIVI
                     DMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTARLKGTSHSQRGLGK
                     KLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIVDRLLSACPNLRQGYQLYQDIL
                     YAVKKRDQSLFEDCLNREVSGLPETYTTTLRTFKKFLPQIQNALHYSYSNGPLECLNN
                     HIKVLKRNAYGFRSFYNFKLRIMIRHGKTFLTK"
     gene            877..1077
                     /locus_tag="JOX41_002535"
     CDS             877..1077
                     /locus_tag="JOX41_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAY6450232.1"
                     /translation="MIEEEQKNIWDRYYKADPSSKNTKIGESGLGLSIVKELVRLHHG
                     SIEVTSRKNEGTTFLIQFPKEK"
     gene            1153..1350
                     /locus_tag="JOX41_002536"
     CDS             1153..1350
                     /locus_tag="JOX41_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450233.1"
                     /translation="MVECLKNKKMEANFVKAVISGSIVFQEEYRDMEKDFSKKGIELI
                     DYPRSCPILDKEYPEILTTFF"
     gene            complement(1647..3194)
                     /locus_tag="JOX41_002537"
     CDS             complement(1647..3194)
                     /locus_tag="JOX41_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HAY6450234.1"
                     /translation="MNITFLETSDMHGYVSPTDYSGRTDLALGTAKVSSKLKELRAKA
                     DGPVITIENGDFIQGSPLSYYLAKEYGSAKELTDLINQMSYDVQVLGNHEFNYGVDYL
                     EEAIKNYQAPILGANMVNKNDQPYFGNAYKIIEKVGVKIAILGLTTQYIPHWEKPETL
                     AGITFKSIVETAKEYVPLLRKQADLVIVSYHGGFEKDLLTGEDTEALTGENEGYELLQ
                     QVEGIDALFTGHQHRKIAETVHGVPVVQPGYRGEFIGEIRLTVEKKEGQVVVTDHQVA
                     LHSVEKSEPDPEILAAIVPVEEKLEKWLDQPLGKVNGNMRINDPMQARLEEHPYVEFI
                     NRVQLFASGSEISGTALFNNEGKGFGETITMRDVITNYIYPNTLAVIQINGADLRAAL
                     EQTANYLAVENNQIVFNPAFIQPKPQYYNYDMYEGIQYTIDMKQPVGQRITELRFKGH
                     PVLPQQMLEVVTNQYRAIGGGNYAMFGAEKIVREIQIDMTELIADYLNIHPRIEAKVN
                     HNFQVIL"
     gene            complement(3278..4081)
                     /locus_tag="JOX41_002538"
     CDS             complement(3278..4081)
                     /locus_tag="JOX41_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAY6450235.1"
                     /translation="MNILHISDIHFRREYEACEEGYKGMLATMQNPLIPLEQCIHHLL
                     QQTPLDLVIISGDLTEDGEIDDYRYLKTWLENALGETTILVTLGNHDIKEHFWVGWCD
                     EAASSAPYNQIVKYPEFTVISFDNSSYGYADGIVDDQQFQWLKKALEQEKDQPIFLVT
                     HHHLLSHQSSIPKWPGTERFLKLIAPYDIRCILNGHTHHTFTDEINGIPYFTVSSMSF
                     VGEDEGDGFVRFEERHGYNLYHLDQGRIVRQTTENFIPGNILKTLQMKD"
     gene            complement(4084..4866)
                     /gene="phnE"
                     /locus_tag="JOX41_002539"
     CDS             complement(4084..4866)
                     /gene="phnE"
                     /locus_tag="JOX41_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HAY6450236.1"
                     /translation="MMLREMNRRTLLSLVALVILVILSAATLDYSGLSTFSPSMGMDV
                     LRGLGQPDWQFLYDGSGEDLISLLLLTIGIACLGTMIATVLAIPITLISAVNLWQAHP
                     WVTKIGKLICNVLRAFPELVFAIIFVKVVGPGPFAGVMAIGVHQIGMLGKLFTEEMEA
                     MDERLVEEMHAVGANFWQTIFFVRIPYLMPIYCSLALNHFEIAVRSAATLGLVGAGGI
                     GAPLIFAIQTRSWSKVSIILIGVVVTVFILDQITGIIRKRLR"
     gene            complement(4863..5642)
                     /gene="phnE"
                     /locus_tag="JOX41_002540"
     CDS             complement(4863..5642)
                     /gene="phnE"
                     /locus_tag="JOX41_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HAY6450237.1"
                     /translation="MSLKETVHFKWYKHLLILLFLIVCFQGSAWITSADFSQVFQNSN
                     QMTVFLSRFIHPDFSYLPKLVEPMVKTLQMSLLGTVIGLILAIPVSFLATTVVTENRL
                     LSTIFRFLLGLVRTIPTLLLAALFVAVFGIGEATGVLTIAVFTFGMVSQLMFQAIETI
                     DFGPIEAAAAVGANKMQIAIWSIAPQVLSQFASYAFYAFEVNVRASTVLGYVGAGGIG
                     VILNSSLALLNYERVSIIILTILVTVAIVDKLSERVRRSLL"
     gene            complement(5614..6405)
                     /gene="phnC"
                     /locus_tag="JOX41_002541"
     CDS             complement(5614..6405)
                     /gene="phnC"
                     /locus_tag="JOX41_002541"
                     /EC_number="7.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter ATP-binding protein"
                     /protein_id="HAY6450238.1"
                     /translation="MIIFDNVSKVYPNGVVGLKDIDLTIEDGEFVSIIGLSGAGKSTL
                     LRSINRLAETTKGDIRINGTSITKANKKELRQIRRQIGLISQSFNLVKRSTVQKNVLS
                     GRLGYYSTWKSILGLFTKEDYQQTKEALEKVGLSDKLQTRSDELSGGQQQRVSIARAL
                     VQQAPIILADEPVASLDPITTQKVMMDLKNINQTMDKTVIVNLHSVPLAREFSTRVLA
                     LKAAQVVFDGRPDDLTDERLEQIYGNAIFEEKAGEIDELERNRSL"
     gene            complement(6466..7395)
                     /locus_tag="JOX41_002542"
     CDS             complement(6466..7395)
                     /locus_tag="JOX41_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate/phosphite/phosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HAY6450239.1"
                     /translation="MQFKQLAKGFIGVMLLTTLAACGSGNTSSSSEKESKEKLVVQFV
                     PTNNDGSMEAKAKPFAKYLSKKLDREVEVTLATDYSTIVEAMSSGQVDVGIMPPAAYV
                     QAKDAGAADAILTSQLGDYDQETGLPLKDKLTNTFKGEVLVRADSGLNKLTDLKGKNI
                     ATLSPNSASGYIYPVAELKDAGIDPTADTKMTTVNDIPSEITAVLNKQMDAAFVFEGA
                     RNVFASNFPDNDLFKDLKVLYLTKGDIPNDAIAVQPDMSKDLKAKIKETFLNMKDDKD
                     GKEAMALWGHQGYEEAADSAYDTIRDYTKKAAE"
     gene            7590..8273
                     /locus_tag="JOX41_002543"
     CDS             7590..8273
                     /locus_tag="JOX41_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HAY6450240.1"
                     /translation="MKKIHDTKQLTAYVEKHNLQDYMDSDILAMASLLFFEKEEHLIQ
                     TGKTSDYLYFLVDGTVMVYSYSSDTQNICIDYAKPATPLGEASSLWELSPKSSVKAVT
                     KCICISIPLNQYRTQLQKDVRFLQNICQLLSYRLNSGINLANSLTEPVETRLAKFILT
                     HHENERFSFRLTTCASILNVSYRHLLRTITNFREENIIEKKKNYYLIHDIEALEDLAE
                     NISSPVKAE"
     gene            8434..9477
                     /locus_tag="JOX41_002544"
     CDS             8434..9477
                     /locus_tag="JOX41_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HAY6450241.1"
                     /translation="MKKILVSLLFLVSLVTLVGCSQSQGEKQSEKEKSKIALVLGFGG
                     VDDRSFNQAGWEGLEAWGKEKKLTAKKDFTYIETNNPEDNSTNIDQAIRNGFTTIISL
                     SYLQAEELENAAKDNPKLKFALVDGEITGKKNISSATFKDQESAYLAGLAAAYTTKSD
                     QVGFIGGMEGPVIQRFQSGFEAGVKAGATALNKEITVNVQYAASYDSLDKGKAIAASM
                     YKEGVDILYQAAGSTGAGVFQEAKARNENDYSRKVWVIGVDRDQADEGDYKMENGETG
                     NFTLTSTKKNVGAEVKEFAETSHNDKFPGGKHLTFGLKEEGVDLTKGQLSEEAYQAVS
                     DAKEKIISGDFRL"
BASE COUNT         2916 a         1945 c         1886 g         2762 t
ORIGIN      
        1 gagttttatc atgatggacg gacaaagcca tgcattattg gatattgtcg aaaatcgacg
       61 cttgccttat ttagaatgct atttttctcg gttttcatta gcgactcgtg aagccgttca
      121 atggattgtt attgatatgt atgcgcctta tgtttcattg gtgaaaaagc ttttcccgaa
      181 tgctcagttg atcatcgacc gtttccacat cgtccaacat attggcagaa ccttcttgaa
      241 tcatcgagtg aaagaaacca cggcacggct taaaggaact tcccactctc aacgagggtt
      301 agggaaaaaa ttgaaacgct attggaaact cctacaaaaa gaagaagcaa agttaaacta
      361 cgaaaaaagg gtttggcgtg ccagttttaa agattatttg actgaaagtg agattgtcga
      421 tcgactgtta tctgcttgtc ccaacctgcg ccaaggctat cagttatacc aagacattct
      481 ttatgcggta aagaaaagag atcagtcatt atttgaggac tgtttaaaca gagaagtcag
      541 cggtcttcct gaaacctata caaccacttt acgaacgttt aaaaagtttc tgccacagat
      601 ccaaaatgcg cttcactaca gctattcaaa tggaccattg gaatgtttaa acaaccacat
      661 caaagtatta aaacgcaatg cgtacggctt tcgcagcttt tacaatttca aactacggat
      721 catgattcgt catggcaaaa catttttaac caaataaaca gaacagaaag agagtttctt
      781 ctttctgttc tgtccaaatt attctaagat ttctctttac caacatcatt tgacaaagag
      841 cctgtattta ttactgtcga ggacaatggc atcggcatga ttgaagagga acaaaaaaac
      901 atttgggatc gctattataa agccgatccg tcaagtaaaa atacaaagat aggcgagtca
      961 ggtcttggat tatcaatcgt gaaggaacta gtgcgcctgc accacggttc aattgaagtg
     1021 accagccgaa aaaatgaagg aacgaccttc ctgatacaat ttccaaaaga aaaataaaat
     1081 taccagtaaa aaaccgtgga gagatagctg ctattgattt ttgctatgtc ttttctttga
     1141 gaggtatccg gtatggtgga gtgtctgaaa aataaaaaaa tggaggccaa ttttgtgaaa
     1201 gctgttattt ctggaagtat tgttttccaa gaagaatatc gagatatgga aaaagatttc
     1261 agtaaaaaag gcattgaatt aattgattat cctcgctcat gtccgatcct agacaaagag
     1321 tatccagaaa tcttgacgac ttttttttaa atatcgcagc agcggattta ttttttgtat
     1381 ttaatcaaga tcggaaaggg gtattaggct atattggtgc cgcaactttt tcagaaatga
     1441 agtattgtct gatgcaaaat cttattcatg gaaaaaggat caaaatagtc ttatttaagg
     1501 aaccatcaga ggaaaatttt ttgttttgat gaggtagatc gctggctaaa gaatggctgg
     1561 atggaaatca gacagcctaa caatttggca taacaaaggt gtgggcaaaa aactgctcac
     1621 acctttttga attttttatt tatatactac aaaatcactt gaaaattatg attcactttt
     1681 gcttcgatgc gtgggtgaat attcaaatag tcggcaatta attcggtcat gtcgatttgg
     1741 atttctcgga caattttctc cgcaccaaac atcgcataat ttcctccgcc gattgcccga
     1801 tattgatttg tcaccacttc cagcatttgt tgcggaagaa cggggtgacc tttaaaacga
     1861 agttcggtaa tccgttgtcc aacaggctgt ttcatatcaa tagtgtactg aatcccttca
     1921 tacatgtcat aattgtagta ctggggctta ggctgaataa aggctggatt gaatacgatt
     1981 tggttatttt ctacagctaa ataatttgcg gtctgctcca acgccgctct caaatctgca
     2041 ccatttattt gaatcactgc cagagtattc ggataaatat agttggtgat gacgtcccgc
     2101 atcgtgatcg tctcaccaaa gccttttcct tcattattga ataacgcagt tccagaaatc
     2161 tctgagccgc tggcaaataa ttgtacacga ttaataaact ctacataggg atgttcctca
     2221 agacgagcct gcatcggatc attaatacgc atatttccgt tcactttacc taagggttga
     2281 tccaaccatt tctctagttt ttcttctacc ggtacgatcg ctgcaagaat ttctggatca
     2341 ggctctgatt tttcaactga gtgtaaagca acctggtgat ctgtaacaac cacttgcccc
     2401 tcttttttct cgacggtaag acgaatttca ccgatgaact cgccacgata gcctggttga
     2461 acaacgggaa ctccatgaac cgtttcagca attttccggt gctgatgacc ggtgaaaagg
     2521 gcgtcaatgc cttcaacctg ctgcaatagc tcgtagcctt cattctctcc agttagcgct
     2581 tctgtgtcct caccggttaa caagtctttt tcaaatccgc cgtggtaact aacgattacc
     2641 aagtctgctt gtttccttaa tagaggaaca tattcttttg ctgtttcgac gatactctta
     2701 aacgtaattc ctgctaaggt ttctggcttt tcccagtgag gaatgtattg tgtcgttaat
     2761 cccaagatag caatttttac acccaccttt tcgataatct tataggcgtt tccaaagtat
     2821 ggttggtcat ttttgttcac catattggct cctaatatag gcgcttgata attcttaatc
     2881 gcttcctcga gataatccac accatagtta aactcatgat ttcccaacac ttgaacatca
     2941 tagctcattt ggttaatcaa gtctgtaagc tctttggctg aaccatattc tttagcaaga
     3001 taataactca aaggagaccc ttggatgaaa tcaccatttt cgatcgtaat taccggtcca
     3061 tctgcttttg cccgtaattc cttcagtttc gacgatactt tagccgttcc taaggccaga
     3121 tcggttctgc cggaatagtc tgttggtgaa acatagccat gcatatcact tgtctctaaa
     3181 aacgtaatgt tcattctgcg tgctccttta gctgactcaa aatagaaaaa ccgaagcgta
     3241 ttcagctgtt cggtctcttt ttttgattta taatgcctta atccttcatt tgaagtgttt
     3301 ttaaaatgtt gcctggaata aagttttctg ttgtctggcg aacaatcctt ccttgatcga
     3361 gatgataaag gttataccca tgacgttctt caaagcgtac gaagccatcg ccttcatctt
     3421 caccaacaaa ggacatactc gatacagtaa aataggggat cccattaatt tcatcagtaa
     3481 atgtgtgatg ggtatgaccg tttaggatac agcgaatatc gtaaggtgcg attagcttca
     3541 agaaacgttc ggtaccaggc cattttggta tactgctttg gtgagacagt agatgatgat
     3601 gggtgaccaa gaaaatcggt tggtcttttt cttgctctaa ggcttttttc agccattgaa
     3661 attgctgatc gtccactata ccatctgcgt atccatagct tgaattatca aaggaaatca
     3721 ctgtaaactc aggatatttg actatctggt tgtacggggc agaagaggcg gcttcatcgc
     3781 accagcctac ccaaaaatgt tctttgatat cgtgattgcc tagagtaaca agaatcgtcg
     3841 tttctcctag cgcattttcc agccaagtct tcaagtatcg ataatcgtct atttcgccat
     3901 cttcggttaa atctccgctg ataatcacaa ggtccaaggg tgtttgctgc aggagatgat
     3961 gaatgcattg ctccagaggg ataaggggat tctgcatcgt agccagcatt cccttatagc
     4021 cttcttcaca agcctcatac tctctgcgaa agtgtatatc tgatatatgc aatatattca
     4081 ttcttatctc aatctctttc ttataattcc ggttatttga tctaaaataa acacggttac
     4141 gactacgcca atcaaaataa tactcacttt gctccaagac cgagtttgaa tcgcgaatat
     4201 caatggagca ccgattccgc cagcgccaac taagcctaag gtagccgcac tacgaaccgc
     4261 tatttcaaaa tgatttaatg ctaaagaaca ataaatcggc atcaaatagg ggatgcgaac
     4321 aaagaaaatc gtttgccaaa aatttgctcc taccgcatgc atttcttcaa caagtcgctc
     4381 atccatcgct tccatttctt ctgtaaaaag tttgccaagc attccgatct gatggacgcc
     4441 aatcgccata acaccagcaa aggggccagg tccgacgact ttcacaaaaa taattgcaaa
     4501 aactagttca ggaaaagctc gtaaaacatt acagataagc ttgccaattt ttgttaccca
     4561 tggatgtgct tgccagaggt taaccgcact gatcaaggta atgggaatcg ctaataccgt
     4621 agcgatcatt gtccctaaac aggcgattcc aatggttaat aatagcaaac taatcaaatc
     4681 ctcgccgctg ccatcatata gaaactgcca atcaggctga cctaaccctc tcaaaacgtc
     4741 cattcccatg gaaggagaga aggtgcttaa tccagagtaa tccagagtag cggccgacaa
     4801 aataacgaga atcactaaag caactaatga taaaagggtt cttctgttca tttcacgaag
     4861 catcataaca gggacctcct gacacgttca cttaatttat caacgatcgc gacagttact
     4921 aggatcgtta gaataatgat tgaaactcgt tcataattca aaagcgcaag tgaggaattt
     4981 agaataacgc caataccacc agctccgaca tatccaagga cagtagaagc acgaacattc
     5041 acctcaaacg cgtaaaaagc atagctcgca aactgactca aaacttgtgg agcgatcgac
     5101 caaatagcga tttgcatttt atttgctcca acagccgcag cggcttcaat cgggccaaag
     5161 tcaatggttt caattgcttg aaacattaat tgtgacacca taccaaaagt aaagacagcg
     5221 atagtcaaca cgccagtcgc ttcaccaatt ccaaacacag caacaaaaag cgcggctaaa
     5281 agcagggtag ggatggtccg tactaaacct aaaagaaaac gaaagatggt agaaagaaga
     5341 cggttttctg tcactacagt ggtcgctaaa aaactaacag ggatcgctaa aattaagcca
     5401 atgaccgttc caagcaaaga catttgaagt gttttcacca taggctcgac taatttaggt
     5461 aaatagctaa agtctggatg aatgaagcgt gataaaaaga cagtcatttg attggagttt
     5521 tgaaaaacct gagaaaaatc agctgacgtg atccaggcac ttccttgaaa acaaacaatt
     5581 aagaacagaa gaataagcag gtgtttatac catttaaagt gaacggtttc tttcaagctc
     5641 atcgatttcg cctgcctttt cttcaaagat tgcattgcca taaatttgct ctaagcgttc
     5701 atcggttaag tcgtctggac gaccatcaaa gacaacctga gcagctttta acgcgagcac
     5761 acgcgtagaa aactcacgag ccagagggac tgaatgcaga ttgacaatga ctgttttatc
     5821 catcgtttga ttgatatttt ttaggtccat cataaccttt tgagtcgtga ttggatctaa
     5881 tgatgcaacg ggttcatccg ctaaaataat gggggcttgc tgcacgagtg ctcgcgcaat
     5941 ggatactcgc tgttgttgcc caccactgag ctcatcactg cgtgtctgca atttatcaga
     6001 caaaccaact ttttccagtg cttcctttgt ctgctggtag tcttccttcg taaaaagacc
     6061 taaaatactt ttccaagtgg agtaatagcc caaacgtcca gatagcacat ttttctgaac
     6121 cgtactacgc tttaccagat tgaagctttg cgagattaga ccaatctggc ggcgaatctg
     6181 tcgcagctct tttttattcg cttttgtaat agaggttcca ttaatgcgaa tatctccttt
     6241 ggtggtttct gccaagcgat tgatactgcg cagcagagtg ctctttccag caccactcaa
     6301 ccctatgatg gaaacaaatt ctccatcttc aattgttaag tcaatatcct tcaagccaac
     6361 aacgccattg ggatagacct tcgaaacatt gtcaaaaata atcattatcc ttctccattt
     6421 ttttaagtgt aagcaaaaaa aagcttgctg acacttactg atgttttatt ctgctgcttt
     6481 tttcgtgtag tctctgatcg tgtcataggc agaatcagca gcttcttcat agccctgatg
     6541 cccccacaaa gccattgctt ctttgccatc tttatcatcc ttcatattta agaaggtctc
     6601 tttaattttc gcttttaaat cttttgacat gtcaggctgt acagcgattg cgtcattcgg
     6661 aatatcgcct tttgtcaggt acaggacttt taaatcctta aataaatcat tatctgggaa
     6721 attcgaagca aaaacatttc gcgcgccttc aaaaacaaac gccgcatcca tttgcttgtt
     6781 caacactgcg gtaatctcac tcggaatatc attcacagtg gtcatctttg tatctgcagt
     6841 aggatcaatc ccagcatctt tcaattcagc gacaggatag atgtagccgc tagcagagtt
     6901 aggacttaag gttgcgatat tttttccttt taaatcagtt aacttattca atccgctatc
     6961 ggcacgaacc aatacttctc ctttaaaggt gttcgtaagt ttgtccttta atggcaagcc
     7021 agtttcttga tcataatcgc cgagctgaga agtcaggatt gcatctgcag ctccagcatc
     7081 ctttgcttga acataggctg caggcggcat aattccgaca tcgacttgac cagaagacat
     7141 cgcttcgacg atcgttgaat aatcagtagc taacgtcact tctacctcac gatctaactt
     7201 tttcgataaa tacttagcaa atggttttgc ttttgcctcc atactaccat cattgtttgt
     7261 tggaacgaat tgaacaacta atttttcttt gctctctttt tctgagctgc tacttgtatt
     7321 cccagaaccg caggccgcca aagtggtcaa taacatgact ccgatgaacc cttttgctaa
     7381 ctgtttgaac tgcatttttc tcctcctgtt ggatataatt tctaatacgt ctaaatcata
     7441 gcagggaatc aaaatcaatg aagtgacgca cgtcctattt tacacaactt ttacatacaa
     7501 tttacaaaca attataaata attattcgta ttgagccgaa aaacaatcta agctataata
     7561 aagaaaaact tcttagaggt gacgatttca tgaaaaaaat ccatgatacg aagcaattaa
     7621 ctgcttacgt tgagaagcac aacctgcagg attatatgga ttcagatata ttggcaatgg
     7681 cttctttact tttttttgaa aaggaagagc acctcattca aacgggaaaa acctcagatt
     7741 atttgtattt tttagtggat gggacggtaa tggtgtactc gtattcttct gatacacaaa
     7801 atatttgcat cgattacgca aagcccgcta caccactcgg cgaagcctct tcattgtggg
     7861 aattatcgcc gaaaagcagc gttaaagcag tgactaagtg catctgtatc agcattccgc
     7921 taaatcaata tcgaacacag cttcaaaaag atgttcgctt tttgcagaat atttgccagt
     7981 tactaagtta tcgtttaaat tccgggataa atttggcgaa ctcactgaca gaacctgttg
     8041 aaactcgttt agcaaagttt attttgaccc atcacgaaaa cgaacgtttc tcatttcggt
     8101 taaccacctg cgcctcaatc ttaaatgtca gttatcgaca tcttttacga acaatcacga
     8161 attttcgtga ggagaatatt atcgaaaaga aaaagaatta ttacttgatt catgatatcg
     8221 aagctttaga ggacttagct gagaatataa gtagtccagt aaaagcagaa taacagctat
     8281 aaaaaaacag cagtcagaag tgattgctgg ttttttgata gtggagaaat tgggaaacgg
     8341 aaaatcttcg ttgaagagta gtgttctata tattggtatg ctatactttt aaaagttcaa
     8401 tgtgtcaaga cacataaaaa ggggagaaaa attttgaaga aaatacttgt ttcattgttg
     8461 tttttggtgt cattagtaac gttagtcggc tgtagtcagt ctcaggggga gaagcaaagt
     8521 gaaaaagaga aaagtaaaat cgctttggtt cttggatttg gcggggttga tgaccgctcc
     8581 ttcaatcaag ctggctggga aggattagag gcttggggaa aagagaaaaa gctgacagca
     8641 aaaaaagatt ttacgtatat agaaacgaac aatccagagg ataacagtac caatatcgat
     8701 caggcaatca gaaacggctt taccaccatt attagcttga gctacttgca agcagaggaa
     8761 ctggaaaatg ctgctaaaga taatccaaag ttgaaatttg ccttggtaga tggtgagatt
     8821 actgggaaaa agaatatctc atcagcaacc tttaaagatc aagaaagtgc gtatttagca
     8881 ggactagctg ccgcatatac gacaaaaagt gatcaagtag gctttattgg tggaatggaa
     8941 gggcccgtga tccaacgttt ccaaagcgga tttgaagctg gcgttaaggc aggggccaca
     9001 gcactgaaca aggaaattac tgttaacgta caatatgctg catcctatga ttcgctagat
     9061 aaaggaaaag ctattgctgc ttctatgtac aaagagggag tcgatattct ttatcaggcg
     9121 gcaggaagta ctggagctgg ggtgttccaa gaagcaaaag cccgcaatga aaacgactat
     9181 agcagaaaag tatgggtgat tggtgtagat cgcgatcaag cggatgaagg ggattataaa
     9241 atggagaacg gcgagacagg gaatttcacg ttgacttcta caaagaaaaa tgtcggtgca
     9301 gaagtcaaag aatttgcaga aacttctcat aacgataaat ttcctggcgg caagcatttg
     9361 acctttggtt tgaaagaaga aggggtagat ctgacaaaag gacaattatc agaggaagcc
     9421 tatcaggcag tttcagacgc aaaagagaaa atcatcagtg gtgatttcag actgtagaca
     9481 aagtccattt tatggatgat gtctacagt
//
LOCUS       DADLIO010000096         9437 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.099, whole genome shotgun sequence.
ACCESSION   DADLIO010000096 DADLIO010000000
VERSION     DADLIO010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9437
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.099"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            2..74
                     /locus_tag="JOX41_002545"
     tRNA            2..74
                     /locus_tag="JOX41_002545"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            78..150
                     /locus_tag="JOX41_002546"
     tRNA            78..150
                     /locus_tag="JOX41_002546"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:111..113,aa:Phe,seq:gaa)
     gene            155..225
                     /locus_tag="JOX41_002547"
     tRNA            155..225
                     /locus_tag="JOX41_002547"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:187..189,aa:Gly,seq:tcc)
     gene            238..311
                     /locus_tag="JOX41_002548"
     tRNA            238..311
                     /locus_tag="JOX41_002548"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:272..274,aa:Ile,seq:gat)
     gene            323..394
                     /locus_tag="JOX41_002549"
     tRNA            323..394
                     /locus_tag="JOX41_002549"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:356..358,aa:Glu,seq:ttc)
     gene            660..1853
                     /locus_tag="JOX41_002550"
     CDS             660..1853
                     /locus_tag="JOX41_002550"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HAY6450242.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            1983..3455
                     /locus_tag="JOX41_002551"
     CDS             1983..3455
                     /locus_tag="JOX41_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAY6450243.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            3538..4326
                     /locus_tag="JOX41_002552"
     CDS             3538..4326
                     /locus_tag="JOX41_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HAY6450244.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(4393..5061)
                     /locus_tag="JOX41_002553"
     CDS             complement(4393..5061)
                     /locus_tag="JOX41_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HAY6450245.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQIMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            5176..6888
                     /locus_tag="JOX41_002554"
     CDS             5176..6888
                     /locus_tag="JOX41_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6450246.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            6891..8663
                     /locus_tag="JOX41_002555"
     CDS             6891..8663
                     /locus_tag="JOX41_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6450247.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENCKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
     gene            complement(8745..>9437)
                     /locus_tag="JOX41_002556"
     CDS             complement(8745..>9437)
                     /locus_tag="JOX41_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAY6450248.1"
                     /translation="FANRRYGLKYNPVNGVSLARKPKTNEEIKKEKDGYLSKEEVQMI
                     ASKQKSSHQQSRYSLITKFLFLTGLRYGELISLTESDYDGNKITVSGTYDYELKIKTT
                     TKNTGSYRTIELSSNAKEIIDQLIEENKLIKNNKDKYIFISKNGNPISIQAYNQSLRA
                     VSKELNLDKKVSSHMLRHSHISLLTELGIPLKAIMDRVGHEDSKTTLKIYTHTTKNMQ
                     NQLVEKLGKIEI"
BASE COUNT         2833 a         1582 c         2045 g         2977 t
ORIGIN      
        1 tggttccgtg gtgtaggggt taacatgcct gcctgtcacg caggagatcg cgggttcgat
       61 tcccgtcgga accgtttggc tcggtagctc agttggtaga gcaatggatt gaagctccat
      121 gtgtcggcag ttcgattctg tcccgcgcca ttatgcgggt gtagtttagt ggtaaaacca
      181 cagccttcca agctgttgtc gcgagttcga ttctcgtcac ccgcttttag tttttatggg
      241 cctatagctc agctggttag agcgcacgcc tgataagcgt gaggtcgatg gttcgagtcc
      301 atttaggccc atttatttta ttggcccgtt ggtcaagcgg ttaagacacc gccctttcac
      361 ggcggtaaca cgggttcgaa tcccgtacgg gtcatggaag atactttttg agtatctttt
      421 tctttttatc tgaaagaatg attttaaaaa gcttagcaga gttatcttta tggatgattg
      481 tgctaagctt ttttggacag ttctaatgta aaatattttt atatttttta agcaaaaaaa
      541 tgaaaaaata cgagcagaaa actgttttat ctgctatact tggttcgttg caagttcccg
      601 aaaggatccg caggacggag atgccttgta accgaattta actaggggga atcattataa
      661 tggtagaaag acacttattt acatcagaat ctgtttctga aggacatcca gataaaattg
      721 ctgaccaaat cagtgatgca atcttggatg caattttaaa acaagatcca acagcacgag
      781 tagcgtgtga aacgtctgta acaactggtc ttgttttagt atttggagaa atatctacga
      841 cggcatatgt agatattcaa aaagtcgtac gggaaacaat aaaagaaatt ggttatacac
      901 gtgcaaaatt cggatttgat ggagatacag cagctgtatt ggttgcgatt gatgaacaat
      961 ctcctgatat tgctcaagga gttgatgaag cacttgagat ccgggatgaa gataaaaaag
     1021 acgtattaga tgagattggt gctggtgacc aaggtttaat gtttgggttt gctgtagatg
     1081 aaacaccaga attgatgcct ttaccaatcg ctttgagtca tcgtctggta cgacgcttgg
     1141 cagatttgcg taaatcaaat gaattaacgt atttacgtcc agatgcaaaa tctcaagtaa
     1201 cggttgaata tgatgatcaa ggacaaccgg aacgcgtaga tacaatcgtt atttcaacac
     1261 agcatgatga tgcagtagat aatgaaacaa ttcgtcatga tgtcatcgaa aaagtagtga
     1321 aggaagttat tccagctgaa ttattagatg atcaaacgaa atattatatc aatccgactg
     1381 gccgatttgt cattggtggt cctcaagggg atgccggatt aacaggaaga aaaatcattg
     1441 ttgatacgta tggcggttat gctcgtcatg gtggcggtgc tttttctggt aaagatgcga
     1501 caaaagttga ccgttctgcc agctatgctg cacgttatat tgctaaaaac attgttgcag
     1561 cagggcttgc tcgcaaagca gaagtacagc tagcttatgc gattggtgtt gctcaacctg
     1621 tttcgatctc aatcaatact ttcggtactg gaacggttcc ggaagaagaa ctgattgctg
     1681 cagtgagaga aaacttcgat cttcggccag caggaatcat cgagatgctt gatttgcgtc
     1741 gtccgattta caaacaaaca gctgcttacg gtcattttgg tcgtacagat gtagatttgc
     1801 cttgggaaca tacggacaaa gtagatgcgt tgaaagcaag tttagcaaaa taagttatat
     1861 tcagctggaa cgatcgccaa gtggtggttg ttccagcttt ttttatggca gttaacctct
     1921 tgaaaaagat agtaattatt tatctatttt tagatcctgt cataatgaaa gggaggaata
     1981 agatgaaaaa agaaacaaat gttactttgg tcacagtgag tattttcatt gcaacgttca
     2041 tgacggctat tgaaggtaca atcgtaacaa ccgctatgcc aacgattgtc ggttcattac
     2101 atggaatgga aatcatgaac tgggtatttt cgatttattt gctgacaaac gctatgctta
     2161 ctccgattta cggaaaactt gcggataaag tgggacggaa accaatcttt atttttggga
     2221 cattattgtt tattatcggt tcgttatttt gcggtttatc tcaaagcatg attgggttga
     2281 ttgctgctcg tgcgattcaa gggatgggtg ctggggcaat gatgccagta gctttgacga
     2341 tcatcggcga tctttattct attgaaaagc gagcaaaagt tttaggtttg aatagttcag
     2401 cctgggggat tgccagtgtt tttggaccgc ttgcgggagg attcatcgtt gaaacgatca
     2461 gctggcactg gatctttttt atcaatgtgc cgatcggaat tctattaatt attttgattt
     2521 ggctatattt aaatgaacca aaaatcatac atgagtctaa accaatggat atttttggta
     2581 gttttagttt gatggccatg cttgtctcat tgctgttagg gttccaatta ttaggagacg
     2641 aaggaatgag tccgcttgtt tctgctttgc tgctaggtag tatcgtaatg ttaggtattt
     2701 ttgtttttgc cgaaaaaaga gctaaagatc ctgtcatcat gatgcattta ttcaaaaatc
     2761 cactatttgt tgtggtcaac ttggctgcag cattggctag tggttttttg atgggaatcg
     2821 atgtttatat ccctatgtgg atgcaaggtg tattagggct gaatgcagca attggtgggc
     2881 tggtattagc accattatca ctagtctgga tggtcggttc tttccttgca agcaagtgga
     2941 tgactcaaat gaaaactcat tgggtcttga gaattggact actaatcgca gctattgggg
     3001 gcgcttggtt gtatcttatg cctttcagaa gtaactattt atggtttttt gctatatcaa
     3061 cggtcatcgg tataggctta ggtgtgacca tgactacctc gactgtcagt gcacaaaata
     3121 gtgtatctcg tgaccagctt ggtgtagcaa cttcttttaa tacgttagtt cgaacaattg
     3181 gtcaaacagt catggtttct atttttggtt tattgataaa tggggtaact aaacgagaac
     3241 ttgcagcagc aaatttaaca aatgatgcag atatcatgaa taaactggtg aatccacaaa
     3301 cggctaaata tattgatgcg gatattttgt taccattaag aaaaattctt tatgatgggt
     3361 tacattccgt ttatctagtt ggcttgttac tcgtgatcat tgctttggtc ttaacgcttt
     3421 tcgttcatga aaaaagtggt aaaataaaac agtagtttcg gttaagatat gtacgtagcc
     3481 gaatcattca aatttaaagt tattcaaaaa taacttctta ctaaggaagg cgaaaatatg
     3541 gcatttattc aagcaaatat ttattcgaat gtgttagaaa tggaagtcaa tctaaatgtg
     3601 atactaccgc aaacaacaaa aaaggtgatt ggcaccagtt cagagcaaga gacaacggat
     3661 atacctgttt tatatttact tcatggaatg ggtggcaatc atagtgtatg ggaaagacgt
     3721 acgtcgattg aacgttatgt agcaaactac ggattagctg tcatcatgcc atctactgat
     3781 cttggctggt acacagatac agtttatgac atgaagtatt ggacattcat tgcagaagag
     3841 ctacctgaga tttgtcatga attattcccg caattaacaa gaaaaagaga aaaaacatat
     3901 gccgctggat tatcgatggg cggatatggc gcgttaaaac taggccttgc aaaatcagaa
     3961 aatttcgcag cagtaatctc tctttcaggc gctgtttctg taggaaatcg aatggatgat
     4021 cttttgatgg ttcgtaaagc atctttttgg gaagggatct ttggaccatt ggatcaaatc
     4081 gaaggttcaa aaaatgatcc gcaatactta ttgaaagaac tagtaaaaag cggaaaacca
     4141 gttccaagat tttatatggc ttgtggggaa tctgattttc tttatcaggc aaatcaggaa
     4201 atggtatctg ctatgcagga acaaggcttg gcggtcacct ttgaacaagg acctggcgat
     4261 cataactgga tcttctggga ccaatggatt caacgtgcat tggcgtggct aatggaagaa
     4321 aaataaaaaa agagtcttaa aaagatagct cctatagaga tcacaaacat agtgatctct
     4381 ataggagctt ttttactgct cgttttctct tcttttattt tgttggcata agccttcaat
     4441 ataggtttgt gcactcgtta gaaagagtgc tttttcattc aattctgcat gggactgcat
     4501 actttcttta aatccctcta attgattttc aactacataa ttacgcataa atagaactgt
     4561 ttctttcaaa aattcatttc cgtccataat tttttgtcga agctgctgtt catgctgctg
     4621 atccattaac tgtccaatca ataaattgtg gagagaggca atggcctgat gactttgggt
     4681 gactgaaaat ccttcacgaa caagtaattg gatcatttgc tccaaatgtt ctaatcgact
     4741 cggaaaagcg ggcacagtat tgatttctaa ttctgcccca caagggaaac gtgtataaag
     4801 gtcatagtaa ttttccatat actgcagcaa ctgttcattc caaggcaaag ttggatctgg
     4861 aagcgctaat tcttcttcca ttgtttcagc cattatttgc aagagctgtt gtttgttttt
     4921 gaaataccaa tataaagcag gtgcttgaac atgaattctg tttgcgatgt ttcgcatgga
     4981 aagctgcgaa agagcttgtg tttcagccag gatatcaaag gcggcctgaa tgatgattgc
     5041 ttgagaaagc tttatttcca ttttatcaac ctcgtgtatt gcattatctt tttaaacatg
     5101 gtaaattgtt agtcggtcta attttacagt gttaaattag tcctgtcaat ttaaacaaag
     5161 gggtgtaatc aacgaatgaa attaatctta cgacatgcga aaaaatataa agtagctgtt
     5221 tttatttcct tgctgtccgt agcagtcatg gttgcagcag cattatggca acctaagtta
     5281 ctacagcaag tattggaagc tattattaca gaagataatg atgaaatgaa aacaattggt
     5341 atttacctga tcagtctggc tttgctagga ttagccgcag gtgtaacgaa cacgattttc
     5401 tctgcaaaag tagctcaagg cgtaagtgca gatatccgag aagaagcatt tcgaaagatc
     5461 cagacatttt catttggaaa tatcgaacag ttctctgctg gaaatcttgt tgttcgtcta
     5521 acaaatgata tcacgcaaat ccaaaattta gtgatgattt ctttgcaatc actttttcga
     5581 attccattct tatttattgg tgccttcatt ttagctatga tcacgatgcc gcaattatgg
     5641 tggatcatcg tagcgcttat cgttacggta tttctgatta cggcactttc atttacaagg
     5701 atgggcaagc acttcatgat cattcaaaaa ctgattgatc gtgtgaatag cattgcaaaa
     5761 gaaaacttac tagggattcg tgtagtgaaa tcttttgtac aagaagaaaa ccaattgaag
     5821 tcattcagca aagtaagtga ggacttaaca aaacacaaca tcatagtcgg tacattattt
     5881 tctgtgatga tcccgtcctt catgctggct gccaatttgg ctgtggttgg ggcgatcttt
     5941 tttgtgagcg atcttgttaa agatgatcct acgttaattg gtggaattgc ttcattcatg
     6001 aactacttga tgcagattat gatggcaatc attattggcg gaatgatgat gatgatgact
     6061 tcaagagcag ccgtatcgct gaagcggatt gcggaaattt tagatgctga accagatctt
     6121 acttatttag acgttccaga acaagagttg acgggttctg tcacttttga ccatgtttct
     6181 tttcgttatc ctggtgagga tacagatacg cttaaagata tcagcttttc tatcaaacct
     6241 ggagaaatgg ttggtatcgt cggggcgact ggtgccggga agtcaacact agcacaattg
     6301 atccctcgtc tatttgatcc gacagaaggc aaagttgaag taggtggtgt agatcttcgt
     6361 caagtaaatg aaaagagttt aagacaaacg gtttcctttg ttttgcaaaa agcaatttta
     6421 ttctcaggaa cgattgctca aaacttgcgc caagggaaaa agaatgcaac agaaaaagag
     6481 atggaacatg cttcttctat tgctcaagca aaagaattca tcgaaaagtt atctgatcgt
     6541 tacgaagcac caatagaaga acgtagcagt aacttttctg gtggtcaaaa gcaacgttta
     6601 tccattactc gtggcgttat cggtaatcca aagatcttga tcctagatga cagtacgagt
     6661 gcactggatg ctcgctctga aaagctggtc cgagaagcac tcgatcgaga tttgaaggga
     6721 acaacgacga ttgtcatcgc acaaaaaatt gcttctgttg tcaaagcaga ccgcatctta
     6781 gtattggatg aaggcagatt agtcggcgaa ggaacccatg aggaattggt agctggaaac
     6841 cgtgtctatc aggaaatctt tgaaactcaa aaaggaacgg aggagtaagt atgactgatc
     6901 taataaaagc aagtaaattt ttctatcact atttgaagcg gtacaaactc tcctttttct
     6961 ttatctttat cacagtgatc attgctacct atctacaagt aaaggcacct caatacatcg
     7021 gggaagcttt tcaagaatta gctaattacg taggaggctt gatgcaaggc gtagacgata
     7081 aaagcaaatt tgtttctgta atatggaaac tcttgctgtt ttatgtacta gctagtgcag
     7141 ccaactttat ctatagtatt ttgttcacac aagtagtagg gaagtcaacg aaccgaatgc
     7201 gtatcggtct attcaacaaa ttggaaaaat tgacgatccg tttctttgat tctcatcaag
     7261 acggtgaaat tttaagtcgt tttaccagtg acttagataa tattcaaaat agtttgaacc
     7321 aagctttgct tcaagtcatc acgaatgctg ttttacttgt cgggatcttg atcatgatgt
     7381 tccgccaaaa tgtagagtta gcttgggcta caattgcttc cactccagta gccgttttga
     7441 tagctgtctt gattatccgc aaagcacgga aatatgtgga tcttcagcaa gatgaagtgg
     7501 ggaaactaaa tggttatatg gatgaaaaaa tcagcggaca acgtgtcatc atcacaaatg
     7561 gcttacaaga agaaacgatt gaaggattct tagagcataa tcaaagtgtt cgcgaagcaa
     7621 ccttcaaagg acaagcttat tctggtctac tatttccgat gatgcaagga atgtcactgg
     7681 tcaatacagc gatagttatc tttttcggcg gctggttagc attaaatggt gatttggaac
     7741 gttcggtggc attaggctta gttgtgacat tcgtccagta ttcacaacaa tattaccaac
     7801 cactgatgca gatttcatct ggatacagca tgatccaatt agcgattaca ggggcaagac
     7861 gattgaatga aatatttgat gaaaaagatg aagtcaaacc agaaaactgt aaagcatttg
     7921 atggtgttga aaaaggtctt gcgttgcagc acgtagattt tggttattct ccagaaaaac
     7981 tagtcttgaa agatgtctcg atcaatgtgg acaaaggaga aatggttgct cttgttggtc
     8041 caacaggatc ggggaaaacg acgatcatga atctgctaaa ccgtttttac gatgtcaatg
     8101 atggttcagt agtcatcgat ggaatagata tccgagatta tgatcttgat gcattacgta
     8161 gacatgtagg aatcgttttg caagaatctg tattgttctc cggaacgatc aaagacaata
     8221 tcacattcgg caaaccggac gcttcagatg aagaagtcat caatgcagca aaacaagcga
     8281 atattcatga cttcatcatg acgttagaaa aaggttatga tacagagata tccgaagaaa
     8341 ataacttatt cagtacaggt caaaagcagt tgatcagtat tgctcgaacg atcatcacaa
     8401 atccatcttt attgattttg gatgaagcaa caagtaatgt agacacggta acagaagcaa
     8461 ggatccaaaa agcaatggat gaagcaatca aaggaagaac cagctttgtg attgctcacc
     8521 ggctgaaaac aatcttgaat gcagatagaa tcgttgtctt gcgtgatggg gaagtcattg
     8581 aagaaggcag tcatcacgag ttattagcag aaaatggatt ttatgcggaa ctttatcata
     8641 atcaatttgt atttgaaagt taaattaaaa gaacctcgtt ataacggggt tctttttata
     8701 tattttatgt tgtttgtttt tataaggggc agaaaagggg caatttaaat ttctattttt
     8761 cctagttttt ctactagttg attttgcata tttttagttg tatgagtata aatctttaat
     8821 gttgtttttg aatcttcatg tcctacacga tccataatgg cttttaatgg gattcctaat
     8881 tctgtaagta gagaaatgtg ggaatgcctt aacatgtgag aagaaacttt tttatctagg
     8941 tttaattctt tggatactgc tcttaaagat tgattatatg cttgaataga tatcgggtta
     9001 ccatttttag agatgaaaat gtatttatct ttattattct taattaattt gttttcttca
     9061 attaattgat ctatgatttc tttagcatta cttgataatt caatggttct ataagaacct
     9121 gtatttttag ttgttgtttt aatttttaac tcgtaatcat aagtaccaga aaccgtaatt
     9181 ttattaccat cataatcaga ttcagtcaaa gatatcaatt caccataacg tagtccagtt
     9241 aaaaacaaaa atttagtaat taaagaataa cgtgactgtt gatgtgaact tttttgttta
     9301 ctagcaatca tttgaacttc ttcttttgat aaataaccat ctttttcttt ttttatttct
     9361 tcgtttgtct taggttttct tgctaaagaa accccattta cgggattata ttttaatcca
     9421 tatcgacggt tggcgaa
//
LOCUS       DADLIO010000097         9435 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.100, whole genome shotgun sequence.
ACCESSION   DADLIO010000097 DADLIO010000000
VERSION     DADLIO010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9435
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.100"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            <1..1101
                     /locus_tag="JOX41_002557"
     CDS             <1..1101
                     /locus_tag="JOX41_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAY6450249.1"
                     /translation="KKETIVRFEQYNHMPLVTRLKKQRYTCKNCRTHWTAQSYFVRLS
                     HSIADHVRYKIASLLTEKVSLSFIAKSCQVSLTTVTRTLKEFKSYLPKPSKKILPRVL
                     MVDEFRSHASIEDKMSFICADGETGNLIAVLPTRKLPRLTSYFLGCTNPEEVEFLVTD
                     MNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQALNELRIREMNELRKAGQKSQAEKLKK
                     NWRFLLKNRASINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSAPLKEAYPFFHELV
                     EAFRDKDPDLFFSLLAELPETLDDGFREKLQNLLTYEEGITSAMIYPYSNGKIEAKNT
                     HIKTMKRVSYGFKSFENMRIRIFLINQLINVR"
     gene            complement(1280..1615)
                     /locus_tag="JOX41_002558"
     CDS             complement(1280..1615)
                     /locus_tag="JOX41_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAY6450250.1"
                     /translation="MKMNTNDIATVYVAFTAAEGGKRRPVYILKNGLDTISFLSITSK
                     YHTKSDKIKLKYVEIRDWKQAGLKKESWIDVGTLNELPKNNKKVKWKKIGELSPSDLQ
                     RLEERMEEL"
     gene            complement(1599..1871)
                     /locus_tag="JOX41_002559"
     CDS             complement(1599..1871)
                     /locus_tag="JOX41_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HAY6450251.1"
                     /translation="MEKMAKLQISMDEKLKNEAESIIDELGMSPKTAVTVFYKQIVEQ
                     GKIPFSIELSEKSKRIHNIQRLAEKLPVQKLDTDEKIEEWFNEDEY"
     gene            complement(2322..3125)
                     /locus_tag="JOX41_002560"
     CDS             complement(2322..3125)
                     /locus_tag="JOX41_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAY6450252.1"
                     /translation="MRFLHLSDIHFRENYQTNLFTAELFPTIKNPQLALEKLLQELSL
                     TVYDFILLTGDLVHEGGISDYQVLRKMLDQYFPTTPYYFCRGNHDRRSVFFEGMSVES
                     NETGEYIHCTNQNGLRIISLDSAQDTQHEGKISIGQMIQLQEWLGTPAEKGTILLVHH
                     PLSWEDPSIVTEVPEGFAELIAESDILGIFVGHIHQGSSAEFAGKKQFMAESLSFGVD
                     EYPDYSLFTNRTGFTSGSLIDGKIFTYQHYLTPHQIEIGRMKKPITGNH"
     gene            complement(3103..4227)
                     /locus_tag="JOX41_002561"
     CDS             complement(3103..4227)
                     /locus_tag="JOX41_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6450253.1"
                     /translation="MGETLELRNIGKKYGEHTILKEIDLAVAAGERIVLLGPSGSGKS
                     TLLRMIAGLEKITSGELFLGTQLANKLPCGEREIAMVFQNYALYPHMTVKENIIFALR
                     ANKIKTADIQHRLEEALKMLGLTPYQDRLPKDLSGGQRQRVALARAVVKRSNYFLLDE
                     PLSNLDVRLRLDARKELVKIHQRYKQTFVYVTHDQIEAMTLADRIVLLNEGRIQMIDT
                     PKNVYTKPKNTFTANFIGSPGMNIMPVTYDQGTLKVASQFLTLNPAWQKQLLQVSGSL
                     YLGIRPEHVTFSKETSDLHGQVKYRELLGQSYAYTVKVDGIEMIVLNEKPTWQIGDAV
                     NLRIEPERMHFFDYQTQENLGYPDYFIEERGNSHALFASL"
     gene            complement(4243..5058)
                     /locus_tag="JOX41_002562"
     CDS             complement(4243..5058)
                     /locus_tag="JOX41_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAY6450254.1"
                     /translation="MKIKRWLPHLLFMFIIIIIIYPLLFIMANSFKPLKDAYQTITSL
                     IPQPFTLENFCYLFENLPIIKITRNTFFIATIITVVKLGVAFFAAYSFTYCRIKGKKI
                     WYFIIIGTMFIPFTVAMIPNYLLIAKLNLIDTTWGVIIPQFADAMGIFLLTQTMREIP
                     VSLLDVAALDNIKQTTVMSKIVFPLTRHAITSTGIWFFITSWNEYVWPVLILRTVDNY
                     TLPLAMQTYISSEGGTNFTVAMAISLITMFVPLVLYAIFQKYIIGTFVSAGIK"
     gene            complement(5048..5929)
                     /locus_tag="JOX41_002563"
     CDS             complement(5048..5929)
                     /locus_tag="JOX41_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAY6450255.1"
                     /translation="MSEMKRYVGYLYLAPAIILLGVFVFYPLIYTIYLSFFDWNMVAP
                     TKEFVGFANYVKVLTDPVFHKVLKNTLSYTVLFVLLSCVFPYITSFLLGIVIEKGQNL
                     YKPLFFIPAVISLVVAGMVFTWILNPVSGPIAVLLGNFGLRLPMWMNLQGWVIAVIAG
                     ITAWKVFGYNFIVIFAAIVGIDQEMIEAAKLDRVPIWRIFFTIVLPMSSSTGLYLLVM
                     TIVQGLQYVFTPIKIITRGGPNNGSANVIYYAYQKAFEMYKVGESSAISVLTLLIFAV
                     FLGVIFKFVEKGVYYEN"
     gene            complement(6005..7294)
                     /locus_tag="JOX41_002564"
     CDS             complement(6005..7294)
                     /locus_tag="JOX41_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002581297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAY6450256.1"
                     /translation="MLKKNLVIGVVSVLSVISLAACGSGNTKTTKKSEGRVTIEYWHV
                     NADTLGGKTVNELVDKYNQSQDKVKVVAKYNPDMYKGLMQNLQASVASKEIPDVVQVG
                     WAFKDYFAENFKYTNPQSLVEEVDPDNADYFKDHFLDNIMALSEKDGKQVGIPYSISN
                     PVLYLNQDILKAAGLDENGPKTWEEVQTFSKIIKEKTGKYGVYIQEPADNWAQQAILE
                     SNGASVIKDGKATFASKDGIAAYELYQRMVKDQTALHTTWEQGVQSFIDGNVAMVYTT
                     IAQRDNIQKNSTFTAKAVESPSWEGKKVKLPAGGAMLAVTSQTDKKKEATWDFLKYLY
                     SVESLAKWTEGTGYLPPRKDVADAQNGLKAFLAENQMMIPAIDQMDKMVSWSSFPGDA
                     GLEAEQKLLDMRDKILSGNSVNETMKATQKEINELLK"
     gene            complement(7522..8166)
                     /locus_tag="JOX41_002565"
                     /pseudo
     CDS             complement(7522..8166)
                     /locus_tag="JOX41_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
     gene            complement(8643..>9435)
                     /locus_tag="JOX41_002566"
     CDS             complement(8643..>9435)
                     /locus_tag="JOX41_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS1182-like element ISEfa7 family transposase"
                     /protein_id="HAY6450257.1"
                     /translation="HTSCDDNGFILSTIITPGNIHDSQVAFQLVKQSKRLFPEINCVV
                     ADAGYKTPKFVHFLTHLNLRPCLPYSRPKGKKGLLSKNEFLYDEYFDCYICPQDQMLA
                     FSTVTREGYREYKSNPKECVNCPLLNQCTISKNHQRVITRHVWGDLMDEVEHLRLTDL
                     NKSIYKKRKQTIERIFADAKEKHGMRWTKYRGLEKVATHTMLVFAAMNLKKLATWLWK
                     GKEPLFFCSKIRNEVDKKLFQARVTSLEQLLSTVWLSVRTAFFVG"
BASE COUNT         2905 a         2008 c         1514 g         3008 t
ORIGIN      
        1 aagaaggaaa cgattgtccg ttttgaacaa tacaatcata tgcctttggt tacgcgccta
       61 aaaaagcaac gctatacctg taaaaactgt cgtacccatt ggacggctca aagttatttt
      121 gtccgactca gccattcaat cgcagatcat gttcgatata aaattgcttc tttactgact
      181 gaaaaagtat ctttgtcttt tattgcgaaa agttgtcagg tatctttgac taccgttact
      241 cgtacattga aagagtttaa aagctattta ccaaagcctt ctaagaagat tctccccaga
      301 gtattgatgg ttgatgaatt tcgttcgcac gcttccatag aagataaaat gagctttatt
      361 tgcgcagatg gtgaaacagg aaacttaatt gctgtcttgc ctacgcgtaa attacctcga
      421 ttaacaagct atttcttagg ctgcaccaat ccagaagaag tagaattctt agtcacagac
      481 atgaacgccg cttacttcca gcttaccaaa cgtgttctgc caaatgcgaa agtagtgatt
      541 gatcggtttc atattgtcaa acacatgaat caggcactca atgagttgcg tatccgtgaa
      601 atgaatgagc ttcgtaaagc aggacagaaa agtcaggcag aaaaactgaa aaagaactgg
      661 cgctttctgc taaaaaatcg tgcaagcatc aaccattatg agtacaaaac atggaaaagt
      721 ttccgagcac caaaataccc atttctcact gaagcaatga tgattgatcg attgcttgag
      781 ttttctgcgc ctctaaagga ggcgtatccc ttttttcatg aattagtcga agcctttcga
      841 gacaaagacc ctgacttatt tttctcctta ttggcagaac ttcccgaaac gttagatgac
      901 ggctttcggg agaagcttca aaaccttctg acctatgaag aaggtatcac cagcgcaatg
      961 atctatcctt attccaatgg aaaaattgaa gcgaagaata cccacataaa gacaatgaaa
     1021 cgagtatcct acggatttaa atcattcgag aacatgagaa ttagaatctt tttgatcaat
     1081 caattaatca atgtaagata acaaaaaatc tgaaccagaa tgtggttcat tctgacccgg
     1141 atttgatttt gcacaactca tcagtcctta ttgacaaaga gccaaaaatc tgagccagaa
     1201 tgaggttcat tctgacccag atttgatttt gtacaaccca tcagtcctta ttgacaaaga
     1261 gcccttcttt ttagtattat tataattctt ccatgcgttc ttccagtcgc tgtaaatcgc
     1321 ttggacttaa ttccccaatt tttttccatt tgaccttttt gttgtttttg ggtaattcgt
     1381 ttagagttcc tacgtcaatc caagattctt tttttagtcc tgcctgtttc caatccctta
     1441 tttcaacgta tttcagcttt attttatcgg atttagtatg atattttgaa gtaattgaca
     1501 gaaacgaaat tgtgtccagt ccatttttta gaatatagac aggccggcgt ttaccgccct
     1561 ctgcagctgt gaaagcaacg tagacggttg ctatatcatt agtattcatc ttcattgaac
     1621 cattcttcaa ttttttcgtc agtgtctagt ttttggacag gcaatttttc cgctaatctt
     1681 tgaatattat ggattcgttt acttttttcc gacaattcaa tagaaaatgg gatttttcct
     1741 tgctcaacaa tttgcttata aaaaacggtg acggctgttt tggggctcat gcctagttca
     1801 tcaataatgc tttctgcttc atttttcaat ttttcgtcca tagaaatttg taacttagcc
     1861 attttctcca cctctttctg acaaacacat tatatcacgg aaagagttca aatggaatta
     1921 atacaactac ttttgaactc cttgaaatgc agtgtattta tctaaatata aggaaaggat
     1981 atagtgctaa atggccttga tagatagaaa agtttcaaaa tccgccacag cgataattga
     2041 agcgaacact caacgacaca cagaacagga aaagactcct aaaagaacca aattaactag
     2101 gacgtgtctg aaaactccac aaagatgtgg tatgctctgg taaaaaacga atggcacaac
     2161 cacgaagacc gatatggttc ttggaaaact ttctccaccc tttttgtaat tggagggata
     2221 gtggtttatt gatagcgatt ttccaagttc ttcaagtgga accagacatt gagcaccacg
     2281 gctaaaaagt gaatgaagtc tttattttta atcaataatt tttaatgatt accagtaatt
     2341 ggttttttca tgcgccctat ttctatttga tgtggagtta aataatgctg ataagtaaaa
     2401 atttttccgt caattaaact gccactagtg aatcctgttc tattggtaaa aagagaatag
     2461 tctgggtatt catctacacc aaatgataaa gattcagcca taaactgttt tttaccagca
     2521 aattcagcac tgctaccttg atggatatgt cctacaaaaa tacctaaaat atcactttcg
     2581 gcaatcaatt cagcaaaacc ttccggaact tcagttacaa tagatggatc ttcccacgac
     2641 aatggatgat gaaccaataa aatcgttccc ttttcagcag gtgtacccaa ccactcttgt
     2701 aattgaatca tctgtcctat cgatattttt ccttcgtgct gggtatcttg agcagaatcc
     2761 aaggaaataa ttcgtaaccc attttgattc gtacaatgga tatactctcc cgtttcattg
     2821 ctttcaacac tcattccttc aaagaaaaca ctgcgacgat catgattccc acgacaaaaa
     2881 tagtaaggtg tggttgggaa atattgatcc aacattttcc gtaagacttg ataatcagaa
     2941 atcccccctt catgtactaa atcacctgtt aatagaataa aatcgtacac tgttaacgag
     3001 agttcttgta acaatttttc caatgccaac tgtggatttt taattgttgg aaatagttca
     3061 gcagtaaaca agttagtttg atagttttct ctaaaatgga tatcagagag atgcaaaaag
     3121 cgcatggcta ttccctcttt cttcaataaa ataatcagga tatcctaaat tttcttgcgt
     3181 ctgataatca aaaaaatgca ttctttcagg ttctatgcgg agattgactg catcaccaat
     3241 ctgccaagta ggtttttcat taaggacaat catttctata ccatcgactt taacggtgta
     3301 cgcataactt tgacctaata gctcacgata cttcacttga ccgtgtaaat cgcttgtttc
     3361 ttttgaaaag gttacgtgtt ctggtcttat gcctaaatac aatgagccac taacctgaag
     3421 aagttgtttt tgccaagctg gattcaatgt taaaaattga ctggctacct ttaatgttcc
     3481 ttgatcataa gtaactggca taatattcat gcctggcgaa ccaataaaat ttgcagtaaa
     3541 agtattttta ggtttcgtat aaacattttt cggcgtatca atcatctgaa ttctaccttc
     3601 attcaataaa acaatccggt cagctaacgt catcgcttca atttgatcat gagtgacgta
     3661 gacaaaagtt tgtttataac gttgatgaat ttttaccaat tcttttcgtg catccaatcg
     3721 taaacgcaca tccaaatttg ataacggttc atctaataaa aaataattac tccgtttaac
     3781 caccgcacga gccaatgcta cacgctgccg ttgccctcct gacaaatctt taggaagtcg
     3841 atcttggtat ggcgttaaac ctaacatctt caaagcttct tccaaacggt gctgaatgtc
     3901 agctgtctta attttattcg cccttaatgc aaaaataata ttctccttta cagtcatgtg
     3961 aggatataaa gcataatttt gaaaaaccat tgcgatctct cgttctccac aaggtagctt
     4021 atttgctagt tgtgtaccta aaaaaagctc tccactcgta attttttcca aaccagcaat
     4081 cattctcagc aaagtagatt ttcctgaacc agatggtccc agtaacacaa ttcgttctcc
     4141 agcggccaca gctaaatcaa tttcttttaa aatggtatgt tctccatatt tttttccgat
     4201 atttcttaat tcaagcgttt ctcccatgat ttgtcctcca atttatttaa tacctgcaga
     4261 aacaaaagtc ccgataatat atttttgaaa aattgcatac aagactaacg gtacaaacat
     4321 tgtaattaaa ctaatcgcca ttgctacggt aaaatttgtc ccaccttcag aactaatata
     4381 ggtctgcatc gccaacggca aagtataatt atctactgtc cgtaaaatta ataccggcca
     4441 aacatactca ttccaagagg taataaaaaa ccaaataccg gtagaagtaa tcgcatgtct
     4501 agtaagagga aaaacaattt tactcatgac ggttgtttgt ttgatgttat ccaatgccgc
     4561 cacatctaga aggctcactg gaatttcccg cattgtttgc gtcaataaaa aaatgcccat
     4621 cgcatcagca aattgtggta ttatcacacc ccaagtagta tcaattaaat taagttttgc
     4681 aatcaacaaa taattaggaa tcatcgcaac agtaaaagga atgaacatcg taccaatgat
     4741 gataaagtac cagattttct tccctttgat tcggcaataa gtaaaactat atgccgcaaa
     4801 aaaagctacg cctaacttaa caaccgttat aattgtagca ataaaaaaag tatttctcgt
     4861 aattttgata attggaagat tttcgaacaa atagcaaaaa ttttccaagg taaacggctg
     4921 tggtatcaaa ctagtaatcg tctgataggc atctttcaat ggcttaaaag aattggccat
     4981 aataaacaat aatggataga taataatgat tatgatgaac ataaataaga gatgtggcaa
     5041 ccagcgttta attttcatag taaaccccct tttccacaaa tttaaatatt acccctaaga
     5101 aaacagcaaa tattaataaa gttaaaactg aaattgctga agattctccg actttataca
     5161 tttcaaaagc cttttgataa gcataataga tcacgtttgc actaccatta ttcggtccac
     5221 cacgagtgat gatcttaatc ggagtaaaca catactgcag accttgaaca atggtcatca
     5281 ccaataaata tagtcctgtc gaactactca taggcaacac aattgtaaaa aaaatgcgcc
     5341 agatgggtac acgatccaac ttagctgctt cgatcatctc ttgatcaatt cccacaattg
     5401 ctgcaaaaat gacaatgaaa ttataaccaa aaactttcca agcagtaata cctgcaatca
     5461 cagcaattac ccaaccttgt aaattcatcc acataggcag tcttaaacca aaatttccca
     5521 acaagacagc aattggtccc gataccggat ttaatatcca tgtaaaaacc atccccgcca
     5581 ctaccaaaga aatcacagct ggaataaaaa ataatggttt atacaaattc tgcccttttt
     5641 ctataactat tcctaataaa aaggatgtaa tatatgggaa cacacagctc agcaagacaa
     5701 atagaacggt ataggacaaa gtattcttca acactttatg aaagactgga tcagtcagca
     5761 cctttacata gttggcaaag ccaacaaatt ctttagtggg ggccaccata ttccagtcaa
     5821 aaaaactcaa atagatcgta taaatcaatg gataaaaaac aaacacgccc aacaaaataa
     5881 ttgctggcgc cagatacaaa taacctacat agcgcttcat ttccgacagc ctcctcatcc
     5941 ttatgtcaaa agcagacgac cttgtttttc ctttcttaca ggcgctgtcg tctgcttgct
     6001 ttgcttattt gagtaactca ttaatttcct tttgagtagc tttcatcgtt tcattgacgg
     6061 aattacctga taaaatttta tcccgcatat ccaacaattt ttgttcagct tctaatccag
     6121 catctccagg aaatgaactc caactgacca tcttatccat ctgatcaatt gctggtatca
     6181 tcatctgatt ttcagctaag aaagctttta atccattttg ggcgtctgca acatctttac
     6241 gtggtggtaa ataaccagta ccttctgtcc atttagctaa agattcaaca ctataaagat
     6301 attttaagaa atcccaagtt gcttcctttt tcttatccgt ttgtgatgta acagctaaca
     6361 ttgcgccacc agcaggtagt ttaacttttt tcccttccca acttggtgac tcaactgctt
     6421 tagcagtaaa agtactattt ttttgaatgt tgtccctttg agcaatagtg gtatagacca
     6481 tcgcgacgtt accatcaata aagctttgca caccttgttc ccacgtagtg tgtaatgccg
     6541 tctggtcttt taccatcctt tgatataatt cataagcagc gataccatct ttagaagcaa
     6601 aggtagcttt gccatctttt attacacttg ccccattact ttctaaaatt gcttgttgtg
     6661 cccaattatc agcaggttct tgaatataca cgccatactt tccagttttt tcttttatta
     6721 tcttagaaaa agtttgaact tcttcccaag tttttggacc attttcatcc aagcccgctg
     6781 cttttaatat atcttgattt aaatataaaa ccggattact aatggagtaa ggaataccca
     6841 cttgtttacc atctttttca gacagtgcca tgatattgtc taaaaaatga tctttaaaat
     6901 aatcagcatt atccggatcc acttcttcta ctaaagattg aggattagta tatttgaaat
     6961 tttctgcaaa ataatcttta aaagcccatc ccacttgtac tacgtccggt atttctttgg
     7021 aggcaacaga agcttgtaaa ttttgcatca agcctttata catatcagga ttatattttg
     7081 ctacaacctt cactttgtct tgagattgat tgtatttatc tactaattca ttcactgttt
     7141 ttccacctag ggtatccgca ttaacatgcc aatactctat cgttacacga ccctccgatt
     7201 tttttgttgt cttggtattc ccactaccac aagctgccaa agagatgaca cttaaaacag
     7261 acacaacccc tataacaaga tttttcttta acataacatt aacttcctcc taatttcttt
     7321 atggccattt ttctaatcaa gaaatattat gaactaccaa tgtaaatttc tagttaattt
     7381 tctgtaaata attcgaaatt tgtgcatttc ggggtacagg gtcactggac atatccatca
     7441 agctaagaat aaagccccca tatggtcatg tatcccatct ccaaatctct taactcctct
     7501 gttttgatta taaaatagtt tattctgtgc tcctttcttc cataaatagg cccatgcaca
     7561 acgtgaggtt atattataaa caccacagcg cgcaaggtac tcaatcgttt ctagttcatt
     7621 gactgtccat acagaaaatg tcaatcctag ctgctgcccc acttcacggg ccaacttagt
     7681 taaccatcct tcatgaatat tgacgatttg aacgctttga taggctaatt tctgtaaggt
     7741 atcgatcaaa tctgcttcgg taatatcccc aagttttttc ccttcgaact gattttcaat
     7801 attataaaat atatgctttc cccaaatcgc agcccaagat aattgtacat agccactaag
     7861 aacaatttgt ggccagattt gataggtttg tgccagcgaa aaaacggcca tttccaatcc
     7921 ctcttctttt aaatcacagt taatggtcat ggttgccttc tcattggcca ctgcttgaaa
     7981 cacctgctca agggttaccg aatctgggac aacttcttac ctgtcatggg ctagtattag
     8041 cgtaccatct gtttgctgac gcacatctac ttcaaaacaa agctggcgat ccaaacaaaa
     8101 gcgaagaaat gcccagctat tctcctccgt attgtcacta ccagagtgtg cagtgatcat
     8161 ggtcattttg acccctcctt taattccgtg attttctccc acacgtccac tataccgatg
     8221 aagcgttaat ttcttgttaa tttcttgtaa attccctgcg ttttttcagt aaactagttg
     8281 taaatcttgc atgctccttc ctacgaactc atgaatcgtc gattttgccc ttctagctag
     8341 tttcaccaat taagtagttc tacattcccc gcttttaacc tactacacct ttttttgttt
     8401 tcagctattc cttcttcttg ctgaaagtcc ttgaggttct ttcttacagg ataccatcaa
     8461 ggtgttcaat ggcttattcc cattgaatga ccgagactta ctatcagatt tctgctcgtt
     8521 gaaccaagtc tttgatacag gatttcttcc gtcatcttct cacaaatacc accttgcgtt
     8581 tctctagcga ttggtcgatg tgcaccctcc cagtggactg tcactacccc tttttgctat
     8641 gcctagccca caaaaaaagc tgtcctcaca gacagccaga ctgtagacaa aagctgttcc
     8701 aaactcgtaa ctcgagcttg gaacagcttt ttatctactt cgtttcgaat ttttgaacaa
     8761 aaaaataaag gctccttgcc tttccatagc caggtggcta atttctttaa attcattgca
     8821 gcaaacacta gcatcgtatg cgtcgcgact ttttccaagc ctcgatactt ggtccaacgc
     8881 atcccatgct tttcttttgc atccgcaaat attcgttcaa tcgtttgttt ccgttttttg
     8941 taaattgatt tattcagatc tgttaggcga agatgttcca cttcatccat cagatctccc
     9001 caaacatgtc tcgtgatgac tcgttgatga tttttactta tggtacattg gtttagcaga
     9061 ggacagttca cacattcttt tggattggat ttgtattctc ggtacccttc tcgagtaacc
     9121 gttgaaaaag cgagcatttg atcttgcgga caaatataac aatcaaaata ctcgtcatag
     9181 agaaactcat tttttgataa tagccccttt ttccctttgg gccttgaata aggcaaacaa
     9241 ggtcgaaggt tcaaatgagt caaaaagtga acaaacttag gtgtcttata cccagcatca
     9301 gcgacaacac aattgatttc aggaaaaagt ctcttcgatt gtttgacgag ctgaaaggcg
     9361 acttgactgt catgaatatt tccaggagtg atgattgtgc taagaataaa tccattgtcg
     9421 tcgcatgaag tatgg
//
LOCUS       DADLIO010000098         8762 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.102, whole genome shotgun sequence.
ACCESSION   DADLIO010000098 DADLIO010000000
VERSION     DADLIO010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8762
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.102"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            5..1087
                     /locus_tag="JOX41_002567"
     CDS             5..1087
                     /locus_tag="JOX41_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017414133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAY6450258.1"
                     /translation="MNDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTDT
                     RVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINAE
                     FKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKIIS
                     LEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVKN
                     DGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKEDG
                     ELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISIT
                     MDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1305..2447)
                     /locus_tag="JOX41_002568"
     CDS             complement(1305..2447)
                     /locus_tag="JOX41_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAY6450259.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2452..2637)
                     /locus_tag="JOX41_002569"
     CDS             complement(2452..2637)
                     /locus_tag="JOX41_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAY6450260.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(2991..3236)
                     /locus_tag="JOX41_002570"
     CDS             complement(2991..3236)
                     /locus_tag="JOX41_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002412373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAY6450261.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(3230..3631)
                     /locus_tag="JOX41_002571"
     CDS             complement(3230..3631)
                     /locus_tag="JOX41_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAY6450262.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            complement(3818..5626)
                     /gene="uidA"
                     /locus_tag="JOX41_002572"
     CDS             complement(3818..5626)
                     /gene="uidA"
                     /locus_tag="JOX41_002572"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003479936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HAY6450263.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDVCKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAYYLQKRWSSIPNFSYKK"
     gene            complement(5649..7415)
                     /locus_tag="JOX41_002573"
     CDS             complement(5649..7415)
                     /locus_tag="JOX41_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HAY6450264.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IITDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(7428..8222)
                     /locus_tag="JOX41_002574"
     CDS             complement(7428..8222)
                     /locus_tag="JOX41_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAY6450265.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGDYVDIEQKYIDTFWKNLTNK"
     gene            complement(8232..>8762)
                     /locus_tag="JOX41_002575"
     CDS             complement(8232..>8762)
                     /locus_tag="JOX41_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAY6450266.1"
                     /translation="PILVLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKA
                     SNMYVFLILSSVGYMGLGVFNTVIWANITDVIDDQEVKSDQREDGTVYAVYSFARKIG
                     QALAGGVGGWTLSIIGYDSLANVQTGDVLEKLYNASTLIPSICFLIVGLILFFLYPLS
                     KDKVLENCELLKQKHK"
BASE COUNT         2839 a         1682 c         1168 g         3073 t
ORIGIN      
        1 agatatcaat gatgatggct caagaaaaaa agtggagaaa gttggcggag acacccgacc
       61 agaggccgaa gctgctttac gaaaagtttt atcagatatt gacgaaacag gacaatactt
      121 tttaggtacg gatactcgag taaaacaata ccttgatttt tggatggagg aatacgttaa
      181 actaaatcta aaatacaata cctatgaaaa ctaccgattt accatcaaaa atcatataaa
      241 cggttattta ggaaagaaaa aacttacgga tctctcccct gctcttttac aaaatttcat
      301 caatgctgaa tttaaaaagg gttactcgaa gaaaacaatg actattactc actctgtcct
      361 taagaatgcg ctgaatatgg cggtttatcc ttggggatta atcaagcaaa atcctatgct
      421 gtatgtaaaa ataccaaaat atgaagcacg accaacgact aaaaaagatc taaaaatcat
      481 ttctcttgag gactttgatc atatgctaga aattactcct gaaggacatc ctttctatat
      541 tcctttgaat attggatttt atacgggaat gcgcgttggc gaagtttgtg gtctgacgtg
      601 ggatgatgtc gatttttcaa atggaacaat tactgtagag aaacaaatgg taaagaatga
      661 cggcgcatgg gtatatggta cgccaaagac aagcagttcc aatcgaacga tttttattgg
      721 acaaaccttg ctagcaattc tgaaaaaaca taagaaacaa caattagaaa atcgaatgaa
      781 gtatggaaag ctctacattg attcaaatgc agtatgtacg aaggaagacg gtgagctagt
      841 tacgccaagt gtagtgaaat ggaatactag gaggatatcg aatgcactct ccctctcttt
      901 taacttccat tctctcagac atactcatgc tacacttctt ctcgaaaatg gcgcaaaaat
      961 gaaagaaatc tctgaacgat tgggccacag cagaatttca attacgatgg atacttactc
     1021 gcatgtaaca gataagatga gaaatgaaac ggtcgatatc atggaaaatc ttagaaagaa
     1081 ttcttgattt ttgccaccga aaaaaaccac cggtggcaaa ccggtggcaa atccatgtaa
     1141 acatggttta ttttttacac tgttttcaaa caaacccttg ctatttcttc ggttcgtcct
     1201 cgtccatttt cgataccgac agctagctta taacccaagg tatatcaaca taaaaaaata
     1261 aaaataggct atgacagcag cgtgacagca aaaaagatgg aaagttaaat atcaaacctc
     1321 gtaatttcat ttgcgagtgc ttgatttgtt tctggatata agtgtccata tttgtccaaa
     1381 gtagttttaa tagaggcatg acctagacgc ttagatattg catagatatt tttattatgt
     1441 tcaattaaaa aggcaacatg cgagtgtctt aatccatgca tatgaattgg ttttactcct
     1501 gcaatttcag ctagtttttt tattctgctt aaaatagttc ttggagatgg cggtaatcca
     1561 tcaaaagaaa aaaccaattc tatatttttc ccaattgatt gttgagtttt tttccatgtt
     1621 tttaaatctt caacggtttg tctgtctaac gaaattatcc gaatacttga tgtatttttt
     1681 gtttcagcaa attcataatc ttgtcttgta cggatgtaaa ttgacttatt tacgctacat
     1741 ctgccattta ttaagtcaaa gtctttccat tgtaacgcta agagctcctc actccttaca
     1801 cctgtaacaa aaataaaacg catcaaacgt ttataaaatt cttcataaaa atccccgtga
     1861 taaacactat tatatacttt cttaaattca tcaactgtcc aaaattctac ttgaggacgc
     1921 tgagttttta ttttacctat agtatctaca ggattttctt caataatttc aagtacaatt
     1981 gcccttttaa aaactactct caacttattg aatatctgtt taatataatt tggtgataat
     2041 ggttgctcaa tgcccttttt tacaacatgg attttcgata aaaactgttg aaattcctgt
     2101 atatgaattg gtcgaatctt tacaacctgc atttctccaa aaaaatccaa tgcacgttgt
     2161 aaaatatgat ctgttttcat atatgttttt tctacagttc ccaacttata ccaaggaaaa
     2221 aaatactctc gataaaaatc atgaaacgtt attccttgca gataaattcc ttgtgaatca
     2281 gaaaaacttt gttttaactc ttcgagtccc cttctagctt ctccttgagt tttgaagcct
     2341 cttctggtca cttgaattct ttttccaaag cgatcttgtc ctaaagttgc agaaaaaaac
     2401 caagtgcctc tttttctgtc tttataaaca ttcgcaattt tcctcatttt actattcctc
     2461 ccaagaaata tggagaactt cttctaaaat tgaaatagga attcttttta tttttgaatt
     2521 acgataaaaa aagtatcctt tctcaactaa aagttcttta cattccttga agattttatt
     2581 agcatagtac tgagaaaaac ctagattaat caaatctttt cgagtagctg ttttcattat
     2641 agcaccttcc ttactttttt tcatttattt ctatcagctg cttttgtcaa aagcacatag
     2701 gaatttcacc tctccccaag tttacggcga gccttacgga agtatcatta tcccaacttt
     2761 aaatcatcgc tttttattga ctataaaaat tattttagaa tatttatcgc tccttcttta
     2821 cagcaagaaa tcatggcgca actaaaatat gctccttaaa gtgttaacgt actgatagaa
     2881 tctatttaat tttcaatgaa caataggttt tctacctaaa agaatctact aattccttaa
     2941 ctattagaag attcttttaa acagaaaaag tggaaagggg atttttttaa ttagttaatt
     3001 ttaaatttta agatcgcttc tattaattta atttctagct gacttatcat atattcatct
     3061 acataggtaa cgaattgacc tacctcgtta aatccatttg tcaaacataa cttagccata
     3121 taagaatgat aatgtttgag tatcatcttg atcgaaattg gatctccttc tagagcagat
     3181 aagataatgg atagtggaac taataggtac tgccgctttt tagatttatc taccataggt
     3241 cataccccat tttcaattgt tcaactgcct tctttcgttg ataccagata ccacttgtgc
     3301 tcatattgag aattttaccg atttcagcat cattaaaacc tgcaaaataa taaagtagga
     3361 taatctttct tcttatctcc gataactgat caattgctgc tgataacttt tgatctgaaa
     3421 ttaatatttc cattccaaat aagaaataga catcttgttc atcaaaatga gtttgggaat
     3481 acctgccttc atttgaatct gccaatggtt cctcattatc ctttatgtta gcgtttcgtt
     3541 ttcgaataga cttagcttcg tttcgtaata cttttttaca gtaggcatca aattggtgtt
     3601 gtatagatat gtcattgtaa tgttgttgca tgataatatg ctcctttttc cccctttcca
     3661 ctaatacaac aatcagaaag cccctttttt tcgaaaaaac tagaaaaaaa acataaaaat
     3721 atttatcatt ctttaaacag aaaatctttc tataaaaaac aaaaaaaaac gattaggcta
     3781 ggctaatcgt tttttgaaca ttcttaaaaa atccaaatta ttttttataa ctgaaattgg
     3841 gtattgatga ccatcgtttc tgtagatagt aagcaatcat tttaggtttt ctatctctag
     3901 taaagattcc tttcttattt ccttgcactc ttaaaatccc ttgacttgtt gcaaaatctg
     3961 caaaattcca cacttgttca ccaacaaaat tttcacatgt atctattact tcgtgatttg
     4021 cttcgtaata agccacttga tactcttctg taaacattgt tggtactgta tcatgaaatc
     4081 cagctactgt atctgctcca tattctgtaa acattattgg cgtatcagga catctttcca
     4141 tccatccatc tagctctttt ttcaacagat attttgcatg tgccagatcc cctcccgaaa
     4201 cataccaacc ataataacga tttaaacata aaacatcgac aatatctcct accttacaaa
     4261 catctggcgt tgattttaga taagtaacga ttgttacagg tcttttctgc ggatcaagtt
     4321 ctttagttaa ttcaactaaa ggttcaaaat attctttagc accttcggaa tccgaatctg
     4381 gttcatttgc aatagaccac attacaacac ttgggtggtt cttgtcgcgt tctatcaatt
     4441 ccttgatcac cgttttatga gaattttctg ttcgtatctc tttccacgta ttatgttttt
     4501 ccacattatc atctaataaa gtggccatga aatttaaatg taaccctact gcaggtactt
     4561 catcaataac tacaatacct tctcgatctg ctaatcgcat aatttcttct gagtaaggat
     4621 aatgtgatgt tctaaaagaa ttagcaccta tccatttcat taaattaaaa tctttaatat
     4681 ttacagcctc attcaaacca cgtccattaa catacgaatc ctcatgctta ccaaatcctt
     4741 taaaataaaa aggtttatta ttaatcaaaa atttgccatt ggtaacctga acactgcgaa
     4801 taccaaattc ttctgtatag gtatcgatca ctttattatc atcaattaaa ctaattttca
     4861 tactatataa ataagcgtct agaggttccc aaaaaattgg attcttaagc tgaatcattc
     4921 ctttctttcc ttcagcttca gctacaagtt gagcctcttc gtcatatatc gctattaaga
     4981 tttttccggt ccattctgta tcgatattga attctacact tgcatccaaa tcagttattc
     5041 ttgtattaat agtaatatca cttatatagt ctttcggagt tgtatataac ttaacaggtc
     5101 tatgaatacc tgcataattg aagaaatcaa aattaactaa gttttccttt tttatatccc
     5161 cattttcctg tactgtttcc ttcataatcc ccacaggtaa agtactatcg tcaataatat
     5221 tgtttacagc aactgtaatt cgattattcc cgtcttttac aaaccgatta atttcagact
     5281 caaatggtgt aaacccacct ttgtgttgag taataaactt tccattcaaa aaaacttttg
     5341 cttcatgtgt tgcagatcca aaacgaagaa ctaatctttc ttctaataat cttttaggaa
     5401 gagtcacttc tttttcatac cacacccatc caacatgatt tctaatgttc tctgtttcaa
     5461 ataaatcatt ataagaagag ggaactgaaa tcggataact ctctttttca tttattggtt
     5521 ctaaagcaag ttcttcctgt aagtcatcat ttgtatctaa tttaaatctc cagagaccgc
     5581 ttaagtcaat tacttgcctc gtctctgtca taatgggata caacatataa accactccta
     5641 tctaaatatt aaataaatgt atcctttaaa ccacaataag catctattgg acttactccc
     5701 ttaaattcag aaagacccat tagtttgtcc accaatattt ctaaagtttc ttgttttcca
     5761 tcataagtat taatataagt ctttacttga ggtacatcag ccaaatgaaa cggacactgt
     5821 acagatacaa aaattgttgg aatttcatga atgtaaaacg gtatatccgg agttccttta
     5881 cttgctggcc agacaattcg ttgaactgtg cctggattaa cattagctat attaatgatc
     5941 aagtcatatt ttttagttaa atttttaatt ggtctcttag cagcatatat tccagctata
     6001 tttttaattt tttcttcttg cgataatcct ttcaattctt cttcaggtga aatgtatttt
     6061 tcaacttcaa atccttttgc tgacaaaatc tgtttcaata aatcaatggc ttgaggtcta
     6121 tttccagcaa ctacttcacc aaacccacct tttaccccat gtacatctac tagtaaaatc
     6181 cttttatatt tttctggtac aataggccaa atatcttgtt tatctttaac taatgtaatt
     6241 gcttggtcag ccacctcttt aaaaattgat ttattttcaa ttaaaccaat tttttccaga
     6301 gcttcttgct taggtaataa aatttgttct tttgcttttt tgtgtaatcc caatttagct
     6361 tttaacccta aaattctttt taaggcatct aataaccgat catcagtgat aattccttta
     6421 cgatagcctt ccatcatata attaaagtct tcatctggat cattaaaaaa tagaaataga
     6481 tcacatccag ctgcaataga agtgggcaat aattctgatc gtttcattgc cccagtcatt
     6541 cctaacatat gactagcatc agtaactact aatccattaa atccgagttt tcctctaagt
     6601 aagtcagtga ttaattcttt tgataaagtt gcaggaagta aatcttcatc tttcagatca
     6661 ggattaaaat gttttgaata agctggcata tggatatgac ctgccataat tgaaggtaat
     6721 ccagcttcta ttaagcctga gtatactttt ccaaaagaat tatcccattc ttccgtacct
     6781 aaactattaa tactaaaaga tagatgctga tctcgttcgt caataccgtc accagggaaa
     6841 tgtttagctg caggcaaaat tccactctcc tgaatacctt tcatataagc taaactaagt
     6901 tctaaaactt tatcagggtt ttgtccaaaa gatcgactag aaatgatagg atttctccaa
     6961 tttctattaa tatctacaat aggagcaaaa ctccagttac atccaatagc cgatgcttca
     7021 atcccagaaa ctctccctaa ttcataagca tatttcgcat catttgttgc accaattttt
     7081 acttctacac caacttcagt accatctgta caagctccgt taccacctgc ttccgtatta
     7141 gcagcaatta atagaggaat tttactttct gtttgtaaga tatagttttg atcatatacc
     7201 tcatcagcag ttcctggatt atatcgtaca gctccaatat ggtactgatt gaccatatta
     7261 ctcaagtaat ttttatcacg actagatccc atattaacaa acaattgacc tattttttct
     7321 tccaaagtca tagaatcaat cgtctcttca atccaagaaa tagcatcttc atctaaatta
     7381 tatggttttt ttcgtaaatc tacttttata gtcattttct ttctcctcta cttattagta
     7441 agatttttcc aaaaagtatc tatatatttt tgttcaatat ctacataatc tcccgataaa
     7501 catttaaata aaacatcagt tcttaagttt tcccatgatt ctttttcttt attgaccaaa
     7561 ataggataaa agaaaacttt atttttattt gcagcttcta gatcaccagg agaatcacca
     7621 atcattaata tcttatccaa atcacaacca ttttcaatta cacttcgaat aatatcttct
     7681 ttttttcctt tatcttgaca acacagttca tcaactaatg ataataattc atgtctttcc
     7741 cattcttctt gaacagcttc cttattagct gagcttacaa taattatctt cccatatttt
     7801 ttcagagctt ttatagtatc tctagcactt aaaaagggtt tatctaatcc ttttgcttga
     7861 ctaatctgtt gattgacttc ttccgaccat tttaaagctt ttaataaatc ctctgactga
     7921 gaatattcta tttccctctt caaagatgga ttagacaatt cttttgttag agatacccag
     7981 tgctttaatc gattaatcga tgttacatca tttttttcta atgttttaac taaacctaaa
     8041 aatctgttta ttccacgagt ctctgaatat aaattaatat tattccaatc ctgtaggaat
     8101 ttttctctat gatgaacatc aaaaatctct gcagcaattg gtccgaaaaa gagattgtgt
     8161 ttataagtca tcgtatccat aacacagcca tctgaatcaa tacaaaatat ccaattattc
     8221 atatttctct cctatttatg tttttgtttt aaaagctcgc aattttctaa gactttatct
     8281 ttagataatg gataaaggaa aaataaaatt aatcctacaa tcagaaaaca aattgatgga
     8341 attaatgttg aagcgttata taacttttct aaaacatctc ccgtttgtac atttgctaaa
     8401 gagtcatagc ctataataga aagagtccaa cctccgacgc ctccagctag agcttgacct
     8461 atttttctag caaaagaata taccgcatat acggtcccat cttctctttg atcagacttt
     8521 acttcttgat catcaataac atcagtaata tttgcccaaa taacagtatt aaacacaccc
     8581 aaacccatat agccaaccga actaagaatt aagaatacat acatattact agcttttatc
     8641 aaaaataaga tcaaatatac tattgctgaa aagaacattc ctactgatgc cagttctttt
     8701 tttccatatt ttttacttaa aaacaaagtt aaaggcgaaa caactattaa aaccaaaata
     8761 gg
//
LOCUS       DADLIO010000099         8494 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.103, whole genome shotgun sequence.
ACCESSION   DADLIO010000099 DADLIO010000000
VERSION     DADLIO010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.103"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(<1..173)
                     /locus_tag="JOX41_002576"
     CDS             complement(<1..173)
                     /locus_tag="JOX41_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009325336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAY6450267.1"
                     /translation="MATKIADELENHVLETGMQKITTHASITAKPFFEKRGYKVINEQ
                     TVELRGQLFTNFL"
     gene            complement(593..1714)
                     /locus_tag="JOX41_002577"
     CDS             complement(593..1714)
                     /locus_tag="JOX41_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HAY6450268.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVMDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYKPG"
     gene            2042..3451
                     /locus_tag="JOX41_002578"
     CDS             2042..3451
                     /locus_tag="JOX41_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HAY6450269.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            3448..4176
                     /locus_tag="JOX41_002579"
     CDS             3448..4176
                     /locus_tag="JOX41_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAY6450270.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSY"
     gene            complement(4304..5215)
                     /locus_tag="JOX41_002580"
     CDS             complement(4304..5215)
                     /locus_tag="JOX41_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAY6450271.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGLALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(5232..6239)
                     /locus_tag="JOX41_002581"
     CDS             complement(5232..6239)
                     /locus_tag="JOX41_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HAY6450272.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSSPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(6236..8365)
                     /locus_tag="JOX41_002582"
     CDS             complement(6236..8365)
                     /locus_tag="JOX41_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAY6450273.1"
                     /translation="MKKKLFRIVGIVFISIVLLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSSTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(8370..8477)
                     /locus_tag="JOX41_002583"
     CDS             complement(8370..8477)
                     /locus_tag="JOX41_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450274.1"
                     /translation="MQDLYGRVGVVQVHPVFEELFHAFDTRPPVQERME"
BASE COUNT         2600 a         1726 c         1485 g         2683 t
ORIGIN      
        1 attaaaaagt tagtaaataa ttgccctcta agttccacgg tctgttcatt aataacttta
       61 tatcctcgtt tttcaaaaaa tggctttgcg gtaatggaag cgtgggtagt gattttttgc
      121 ataccagttt ctaaaacatg gttttccaat tcatctgcaa ttttagtcgc aatacctttt
      181 ccttgatggc tatgtttttg tcacaacttc agtattcctg taacaatacg gatttcagta
      241 tacaacaaca gcttttgaaa agatacttgc aaaaggatta agatatctat gacctgctat
      301 gctcactgat gttgaaaaga atgttttatt aggattgagg taagcaagat agtgaatatg
      361 tccggaaagc ctgtaaaata aggcttttcg gacatatgtg aagttataaa aagatagcga
      421 aaaatctatt tagtatcact aatgttgcga acatatcgtc agaatagtct gacatttatt
      481 tcttgctaaa aatttcaaaa aagtcaagtg ctgacgcagc ggatgactat tttccagaaa
      541 attttagtat gtattcaaaa atcaaacgtg acaacagcta ttaactacat cctcatccag
      601 gtttgtaacg tttgaaccac tcttctgcgg gctcaaacat taagtaatgg aaggtacgtt
      661 tcaattgaaa cagcgtcgct gtcgtattca actcaatttt tatcacataa gtgagaagcg
      721 ttgcgattaa ggtgaggatg acttgattta tcgccccttg ttcactatgt gaatatagtc
      781 gtttaatggt cagattttgt tttaagtgtt tgaacaacaa ttcaatctgc caacgggctt
      841 gatacatgtc ggccacttcg tttggcgata catcaaagag attggtcacc attcgcagga
      901 ttttttgtcc cttggtaaga accgttacca acctaaaacg ctctgtcaca tggttgacac
      961 cgccgacaag aatcacttgt tggtcactga ttatcgtccc atcacgggtt gttgtatctg
     1021 ctacttcaat ttgatccaag atggtaattt ttgtattaga ttttgtccgt gtaacgaaga
     1081 aatagccgtc acgatttagt ttgtctaaca acttgtaatc aaagtagccg cgatccatca
     1141 catacgttgc ttgcgtttta tcaacaagaa cttcaaggtg attacggtca tgctcactcg
     1201 catttgtcat cgtaaaactt tcaggatact gattggtttt atcaagataa cagagattca
     1261 aatgtagctt gatgccagac tttgttttcc gaaacttggc ccatggaaac catgctttgt
     1321 tcaacggaat agtcgttgaa tcaatcaatt gtagactggt tgtttttgag cttggctgct
     1381 gagcagaaat tctggcgact aattgcgtaa aaatttccat caatacttct tgcttgattt
     1441 ctggcgctct acgagataac gagctgtaac acagggaatc aatgccaagt tccttgcaga
     1501 ggcgctgatc taaaaaggcg cgatcaatct cgcgatagct tggcaattct tcataaaccg
     1561 catgaagtaa cactttaagc gtcgtttgga agtctagttt tttactgtag aaatcaaagt
     1621 cgctaattaa gctttgagag ttttctgata aaccagaaaa atttattgca gaaaaccatt
     1681 tttgaaatga ggtttttacg ttatacttat ccatgcgtga gtccttttta ttggtcttgg
     1741 ataagtcatc cgagaatagt ataaaggact tttttgcgtt tggatagctt tgtattaggc
     1801 ttttgatggg ttaaaaagtc tttgcaacac tagtaattta gtatttatgt ataaattgaa
     1861 agatatttta ccaccactta gtcttcttaa aagtgatcca acattttgtt tgtggcagaa
     1921 tttaactaca cactaatgca gccgaaagta cacaactatg cagcagtttg actgcgaact
     1981 ggtttccttc catcataagt ttgaatgact tagtgatgga ggtacagaaa ggttgttaac
     2041 tttggatgat attaaaacaa taaaacattt gagaaataat cgtgatcagt caattgatca
     2101 gataagaaaa gcaatgaata tcaattggcg aacagcgaaa aaatacgccg atagtgatca
     2161 actattcatt acagatccca ctcgaaaaaa caaatccatg atggatgatg gttggggaga
     2221 aatcatcggt agttggctag aagaagacct acgtttacgc agaaaacttc gtagaacggc
     2281 caaagctatc catgaacaat tgaaaccttt gggtttccct ggctcctatc gaacagtttg
     2341 tgtatacatt tctcaatgga aaaagcagcg ttacgacgaa acgaattacc aagctgtcga
     2401 tcgtcttgat catccgatcg gagaagcaca ggtcgatttt ggaacaatgg aagttatgca
     2461 tgaagatcac atgaaagata tacaacttct tatcatgtca tttccctata gtaatgcgac
     2521 gtccgcaagt gccatgccag ctcaaaacca agagtgtttc ctggaagcat taaaacaact
     2581 atttaatcaa tgcggcggcg ttccaaaaac gatcagaata gataacttaa ctccagcggt
     2641 gaaaaaaaca aaatcaaaat ttgaagaagc acaactaacc gatgaattct tacgtttcac
     2701 cattcattat ggttgtgatg ttcaagtctg taacccacgt agtgggcatg aaaaaggaca
     2761 tgtcgaaaat aaagtgggtt atgtccgata caatttcttc tcgacttcgc caatcatgga
     2821 ctcttttgag tccctaaata agcaacttga agaacaatta aaagcagatc gaaaaaggac
     2881 gcattattca aaacatcaat taatcgaaga tttgtggaag aaagaaaata aagcgttaca
     2941 ttctcttcca caagaggatt acccaatttt taaagaagtg gaagctaaac taaatcgtta
     3001 tcacgaaatg aaattggatc aaacggttat tcatattcct aaagcatatg gctattctca
     3061 attgactgtt gttttgactt ggaataaatt caaagttctt acgcctcatg gagaaatatt
     3121 aatgaacgaa tatcgcccct atatgaacaa aaaaagattg atcccatgga gtgacatcat
     3181 gaaacaatgg agtaataaat tgaatgtcgt tagttattcg aggtattgga agtacttgcc
     3241 tgcacgcctt caaaattatc tagcgattga taataatcac ctgaaataca gacggataaa
     3301 acaattacta agtttattag cgacctacga tatccaacaa attaatgaac aattttacga
     3361 attagtcgtt caagaagacg ccccctctga ctttgatgtg aattggtcaa actatgatgc
     3421 attaacaaaa acaggaggtg tgcaaaaatg attggacaga cgttagaaga ttattgtaaa
     3481 aagcttcgat taagccatat catcacgaac ataccaagag cttctttcga agctccagaa
     3541 caatttatta ccgatttatt ccgtttagaa ctggagacca gacagcagat caaattagaa
     3601 cggatggaaa aattagccaa atttcctgta ccaaaatcgc taaagaacta tgaatggcac
     3661 gaagatattt ttctaccatc tcatctagat aaggagaccc ttgtctctct tgattttcta
     3721 aaaaggcaag aaaacattgt ttgtgttggc tctcctggta cagggaaaac acatctagcg
     3781 atcgcattag ggagaaaagc ctgtagtgaa ggtgtttcaa ccaaattttt ccgagttaac
     3841 aatctcgtag agcaattaga gaatgcatta aaaaaacaac agctagccag tttcaagaag
     3901 cgattcgaaa caacagaatt aattattctt gatgaaatgg ggtacttacc attgacaaaa
     3961 gaaggagctg aacttctctt ccaactgatt tcagattggt atgagcaaaa gagcattatt
     4021 attacctcta atttagaatt cagtcaatgg aatcgagtgt ttatggattc tcgattaaca
     4081 gctgctctcg ttgatcggct aatccatcac gctcacatta tcagcttcaa aggcgaaagt
     4141 ttcagattga aaaattcatt atctaaatca tattgaagga aaaaactagt tgcagcaaaa
     4201 ctctgcactt tcggctgcat ttttttgtaa aaagctattg cacaacacaa acatttgaac
     4261 gacgtaattc caaatgttgg attgctttta gataatcttt tatttattca caattgctaa
     4321 tagtccaatt ttcatttttg tatagtttta atctatactg aaaaacactt gttgttttgg
     4381 acaactcatc aagatactca acaccaacaa tcacttgaat cgctttaccc ttttgtttgt
     4441 aaataggatt cactaattcc acaaatttca aattagtatt aattggttgc atcgcgtctt
     4501 tttcaacata atgctctagt tctttttctg aggctgctgg ataaagcctg aaaaacgtct
     4561 ctaaaaactc ggtgatttct tccgttgtct ttgaatcaat ttttgaatca ctttttactt
     4621 gtcttacttt atgttttgcc ttttctggct taccaatcat agtgggtaaa ctcgttacaa
     4681 tatgattgcc tttttcatct tcaaagatca tcagacgata tgcagaagaa attgattgtg
     4741 tctttttccc ttctgtaatc ttttgatcta ccacaaatga aacgacaaat tcttccgagt
     4801 gtttttcaac atctagaatt tttactgata caacctcgga actagtggga atatccgctc
     4861 gaaccatatc ttggctcaaa gcgagccctt cttctgtaag gtactgctca agattagtca
     4921 ttctcttttc aattacctcc ttgttattct tccatgaaaa atattctttc acaaaatcta
     4981 cagtaaaatt ttctactcca gaggtattca ctattttctc tttcacgacc actttctcat
     5041 gagttgtatg ctgatcaatg gccgtgaagt ttttgtagat tccaaaagca aggctacaag
     5101 acaataaaag ccaaagggca agcaccattt ttcgatgctt gcccacggat actactcgtt
     5161 ctttcttctt ttttggaatc ttttccttgt tacttcgctc aatttttatc ttcattttcc
     5221 attcctcttt tctattgttt ataccgacca gcaccaataa tgtgctgttg ccaatagcta
     5281 tcggtaagat tggtccaacc caccggatct cctgcatgaa acattctgtt ctctcctgca
     5341 taaatgccca catgagtcac ataagtaccg gcatcataag ttgaatgaaa gaaaatcaaa
     5401 tcgcctggtt tggcatcttt taagtcaata tgagtcatag catcatattg atcctgagcc
     5461 acccgaggga gtttcaaacc aactttggca taacaccatt gagttaaacc actacaatca
     5521 aacccagttc cgggacttga cccaccaaat acataagccg ttccttcata cttgaacgcc
     5581 tcgtcaaaaa ttccttggac tgttttatca tcaaactgtg ttgtagttag gtactgcttc
     5641 actaataagc aataaaacat attgccatag ttataccgcc acccactatt ttccttaatc
     5701 gcgatgggat tgggataatc gactttttga ccacccgatt tttcttttga aaaagattcg
     5761 gctaaagcaa aactatgctt ctttccgttt ttcgcgacat aatccaaata cccgtcacca
     5821 tagttataag cctgaatgat actatcttga tcgcatccta gttctttgga acacttaacc
     5881 aaagacgaaa aatagagaca cacttgtttg atggatgcct cggtacttaa tgaattcggt
     5941 gataaacctg ctgattcaga actttgcatg acatcttcca ttgtacctcc agattcgact
     6001 tgaataatcg ccaaaagaat cgaaacatac tctgttatat ctgattcttt ggcatacttt
     6061 tccaccattg aacggtgttt caaaactact tctgagacac tactacctcc aggagaagtt
     6121 ccagaactac cacttccctc accgtcctca ccaaacaaca aacccacaca catcaagatg
     6181 cccacaaaag agatggtcag gaaggttaac gaaataatac tcaatttttt taagttcatc
     6241 ttttctcacc tggctttggt tttgggcgag tgttcttttt tctttgtact tgttgattgg
     6301 ttcgctttgg aaaagtgaat ctctgtttca cttgttgaaa ggaattgttc ttgcttagtg
     6361 gctgagtgct tccgtttgga atgacttctt gactagaaag tttccgtttg atttcaggat
     6421 tcgaatgtac ttgtaccctt ggttttaaag acctattttc tggtagttca tttttctgtg
     6481 gttttatctc cttttttatc ggaacatttt cccttccttt ctcatgacga ttccatgctt
     6541 cgttcaatac tttgcgtttt tcatccattt ttgcgtctct tcgttgtcgt tgtttttctc
     6601 gcaactcccc tcgatttgct ttttcttcga aaggccctcg cttaaagtcc tctggtactt
     6661 ttttcgtctt ttccatgcct ttatgaaggc tgtatttcaa gttagttggt gcatcggtta
     6721 cttgattttt tgcttgtttc gctttgtcct tcacgatttc ttttgtatcg agtacttttc
     6781 caacttttct accaactaaa tttattcgtg attctttctt cgtgcccact ggttgttctt
     6841 gttttttcag atcagaattt agctcgttaa tgcttctcgc ggaatggttc tttctattgg
     6901 acactctatt gatttttgaa ctacctttcc cttttgtaga actggtagct agtttcccac
     6961 caactgctgc accgccacca aaagcaaaag ttcgacccac atttcgatta agctgtcgca
     7021 attttcgatt catcaacatt tgcggtttcc gcatgactcg ccttcccatt gactgactat
     7081 cattactttg aaggttaaac atgctcataa tgtcacctaa tttgaaatag ataccggcaa
     7141 aggtcacaat ttgtagaaaa gctaccataa agaagggata ggtggccgaa atattgaaaa
     7201 acatcgtgga gatactgaat gcagtcgtaa tgactaaggt aactcccgct cgcatcataa
     7261 tcgtattgaa caaacgaata atcgcccttt tgcccaaact ctcatacgtc ggcaacatcg
     7321 acaataagaa actaatgggc agaaacatcg caaagataat gaaaaggatt tgtgagaaca
     7381 acataatccc tgtcagaaga aacacaaaaa aggaaatccc aatattaaac aacactaaaa
     7441 agaccacggt tcctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattat
     7501 cttcaatctc tgctttgact gcttcttccc gatccttacc cttattttca tccggactca
     7561 cggataaaat cttattaacc cgaccctcgc caatttcttc tatattggaa tcatcgaatt
     7621 gtaatagtaa ccagggttgt tgaacttgaa tcgaaaataa actgtctcga atcaaatcca
     7681 cactatcttt tccctggctt tctgaattag gtacaacaat cttggttcca aggctaagag
     7741 ccgcttcact aacgtctgag ctaaagtcat tgatttttgt aatataggtg ggcgcatacg
     7801 caatgaaaga acccgagagt agaaaaatca tcacaaaatt aatgacggtt cggactgctt
     7861 tggtagtttc tcgttttaat aatccggtat acgccacata aactcctaga gctaaaatca
     7921 tcaataatag gaacccaaag tagaatcccg aagtctgtaa tccattttca gtgataccgg
     7981 ctaaagtttg gatattcttt ccaatacttt tagccgtatc cgaaatgaaa tccaacttgt
     8041 aagcttcttg aaccacatag cccgtggcgt ttgataaata cagacttact gtccaaataa
     8101 aattggtaat ggcataaaga ccatacatca cgcttttccc taagccatcc ccccaattcc
     8161 aaggtaacca atcccaagaa ctatccacaa agaaatccag ttgataattg ttcagagaat
     8221 atttggaata aaggtttccg gcttcaactg tatcatcaac cagacctgtc gcctcagcta
     8281 ccgtaccgac taaactcaat agaactgtca ataggacgat gctaataaaa acgattccca
     8341 caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac cggcggacga
     8401 gtgtcaaaag catggaagag ttcttcaaag actggatgaa cttgaaccac acctactcgc
     8461 ccatacaagt cttgcatcaa gcattgaccg tttt
//
LOCUS       DADLIO010000100         8023 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.105, whole genome shotgun sequence.
ACCESSION   DADLIO010000100 DADLIO010000000
VERSION     DADLIO010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8023)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8023)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8023
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.105"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            259..1797
                     /locus_tag="JOX41_002584"
     CDS             259..1797
                     /locus_tag="JOX41_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HAY6450275.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            1794..2759
                     /locus_tag="JOX41_002585"
     CDS             1794..2759
                     /locus_tag="JOX41_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6450276.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            2746..4068
                     /locus_tag="JOX41_002586"
     CDS             2746..4068
                     /locus_tag="JOX41_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAY6450277.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      4131..4235
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            4309..5052
                     /locus_tag="JOX41_002587"
     CDS             4309..5052
                     /locus_tag="JOX41_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAY6450278.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            5067..6059
                     /locus_tag="JOX41_002588"
     CDS             5067..6059
                     /locus_tag="JOX41_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAY6450279.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            6071..6808
                     /locus_tag="JOX41_002589"
     CDS             6071..6808
                     /locus_tag="JOX41_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6450280.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            6798..7520
                     /locus_tag="JOX41_002590"
     CDS             6798..7520
                     /locus_tag="JOX41_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HAY6450281.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(7604..>8023)
                     /locus_tag="JOX41_002591"
     CDS             complement(7604..>8023)
                     /locus_tag="JOX41_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HAY6450282.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         2570 a         1389 c         1751 g         2313 t
ORIGIN      
        1 aaaataaaag ttgtgtgtgt aaaaaagata tagctgattc caagtgacaa tttcgtatag
       61 atttttatgg tattcgtagt gaaaaaacga gaaccaaaaa gttgatccga ctttgttgct
      121 tggattcttt ttttgtcagc atatttagag gtattttttt cttttttttg ttcgtgctgt
      181 aaggttaagg caagacaagt tagttgggaa aaaggaaaga aatgtttata cttaaagaat
      241 aacagaaagg aaggtcgcat gaataatttt atacaaacat taagtgaaag aaaaggcgag
      301 ttgctggaag ctgcatttca acatctgtcc atttctctca tttctttgct gattgcagca
      361 ctgattgcta ttcctttagc gatttgggca gccaatcata aaaaaatggc agaagtctta
      421 ttgcagatca cgggtgtgct ccaaacgatt ccttcacttg ccttattagg tttacttatc
      481 ccatttgtag ggatcggaac tgttccagca ttgattgcac ttgttattta cgctttgctt
      541 ccgattttcc aaaacacgta tattggtcta gctgaaattg acccgtctat tgaagaagca
      601 gcggtagcat ttggtatgtc cagaatgaga cgcttgctga aagtagagct tcccatcgca
      661 ttacctgtca ttatctcagg tatccgaact gccttagttt taatcatcgg tacggctact
      721 ttggcagcat tgatcggagc aggtggatta gggacattta ttttgttagg tattgaccga
      781 aatacacctg ttttgacatt gattggtgcg atcagttctg ccttgcttgc aattatattc
      841 agcggactga ttcgctggtt gcagcataag aaacctcgat attccatcat tactttagca
      901 gcagtggtgt gtttatttgg cggcgtttct ttatatcagt ctgccttgtt taaaaatgaa
      961 accatcacga ttgctggaaa attaggagcg gaacctgaaa tcctgatcca aatgtataaa
     1021 gaattgattg aagacaacac aaaaacagaa gttgaattaa aaccgaattt tggcaagacg
     1081 agttttttgt tcaatgcact ggatcaaggt caaatcgata tctatcctga gttcacaggt
     1141 actgtcctag aaagcttggt gaaggtacct gaagcaatga aaagtgctga tttgacaaaa
     1201 gaaaaaacat atgacgaagc agaagaatta ttgaataagc aattcgatat gacattatta
     1261 aaaccaatgg cttaccaaaa tacgtatgcc ttggcagtca agagatcttt tgcgaacgaa
     1321 catcaactta aaaagatttc cgatttggca gctatctctg atcagatcaa agcgggattc
     1381 acactggaat ttattgatcg ttcagatgga tataaaggaa tccaagaagc atatggcttg
     1441 aatttttcaa gtgtacaaag catggagcca agtttgcgtt accaagcaat caataatgga
     1501 gatgtcaata ttgtggatgc ctattccaca gatagccagc tcaaggagta cgatctagtg
     1561 actctagaag atgatcgagg gttattccca gcttatcaag gcgcaccgct gatgaaaaaa
     1621 gattttgcta aagaacatcc tgaaatcgtt aaagcactga ataaattaag cggaaaaata
     1681 acagaggatc aaatgattga tatgaattac caagtcaatg tcgaaaagaa aaagccgaca
     1741 gaagtagcac gaatcttcct gaaaaatgaa ggattagtaa aggaggaaga tcagtgacta
     1801 aattaatcga gttcaaacat gtgcaaaaaa agtatgatgg aaagtatgtc atcgatgacc
     1861 taaatctggc aatcaaaaaa ggagaaatct ttgttttggt tggtccttcc ggtagtggaa
     1921 aaacaactac tttgaaaatg atcaatggat tatctaaacc atcagcagga gacatctact
     1981 tcaaaggaaa atcgttaaat gaatataatc tgcagaaaat gcggtggaat atgggatatg
     2041 tgctgcagca aatcgctttg ttcccgacca tgacagtcaa gcaaaatatt gaagtcatcc
     2101 ctgaaatgtt aggttgggaa aagcagaaaa gagcagaccg tgtagatgaa cttcttcaaa
     2161 aagttggctt atctcctgat atttatcgag atcgtatgcc tagagagttg tctggaggag
     2221 aacagcaacg gatcgggatc atccgagcta ttgctgcaag cccagatgtg attttgatgg
     2281 acgagccatt tagcgcatta gatccgattt caagaaactc attacaagaa ttggttttgt
     2341 ccttacacga agaattgggc acgaccatcg ttttcgttac gcacaatatg gaagaagcaa
     2401 tcaagctagg tgatcgtatt gcatttatga aggatggaga aattatccaa tgtgacacac
     2461 cagagcagtt attgatgaat cctaaaaacg actacgttcg gcatttcttt gatgaaccga
     2521 aacagacgaa agagtggcga gtagaagatt tagtcgtcaa tggatatttc ttaaatgaaa
     2581 taccagaaaa tgctcgtcaa caagtttgct ttgatacgcc tatgaaagaa gtatattcgc
     2641 ttctttcggt gtatccaagc attgtgatag tagaaaagca aagaagtatt gggtcgctga
     2701 caagtaaaga aatctttgct tttttaagtc gagaggagga aggaaatgaa aacatatgat
     2761 gcaatcatca tcggttcagg tgtgagcggc ttaagtgctg cttatggatt gaaagaagca
     2821 ggtaaaacag tactagtggt cgaagaagat ctatggggcg ggacttgtcc taaccgtgga
     2881 tgtgatccta aaaaagtctt gttaagtgca gtagaggcac gtaatcgggt aaaacaattg
     2941 agtggaaaag gttttaacga gatcccaact gccaactggg aagaacttca aaaattcaaa
     3001 cgaacattta cggatccagt cccagaaagc cgaaaaaaac aattagcaga agctgaaatc
     3061 gatcatcttt caggaaccgc tcgttttttg gatgattcat ctattgaagt caacgaagaa
     3121 gtcttccatg cggattactt agttttggca accgggcaaa gacctacgat cttaccagtg
     3181 gagggaaagg aatacttgaa aactagtgca gactttttat cattgcctgt actgcctaaa
     3241 gaaatcattt ttatcggtgg tggttatatt gcttttgagc tagctacgat tgccaatgct
     3301 gcagggagca aagtaaccat tgtccatcat aatcaacggc cattaaaaga atttgaggcg
     3361 tctttggtag aggaagccgt ccatcaaatg gaagcatctg gcattcagtt tgcttttggt
     3421 gttgaaaccc aaaagatcat ttcagaaggt actcgctatc gtttagtcgg aaaagagacg
     3481 gaattagtag cagatatgat tttttgtgcg actgggagac agccgaatac agaatcttta
     3541 gcacttgagc aagcgaatat cgtctttgat aaacacggaa ttgcagtcaa tgattatctg
     3601 caaacgagca atccaaaaat ttttgcgtgt ggagatattg tttcaaggaa aaccccaaaa
     3661 ttgacaccag tcgccacttt tgaaggaaat tatgtagcta agcggataac ggatgcaaca
     3721 agcgaaccta tcaaatatcc gattatacct acgatcgtct acgccagtcc taaacttgct
     3781 gaagtaggag ttacaaaaag tcacgcctct tcgtcagatc aagtggtaga gatggatctt
     3841 accagttggt tcacctatca tcgtgtcaat gaaccagttg ctaaggctga attgaccttt
     3901 gaccagcaaa attatttgat tggtgctgca gtgattagcg agcaagcaga cgaattgatc
     3961 gatgatttga cactcgtcat caatcaaaaa ttgactaaaa aagagttgga tagctatatc
     4021 atggggtatc cgacattggc aagtgatctc tcctatttat tgaaataatc agcatgataa
     4081 ctaaagcgct tgttgctttt tccttcttgt gctacacttt aaaaaatgaa tacctgtttc
     4141 tggggatgtc gtagacgaca tgagagtaag ttgtgaactt agacccattg aacctgtcag
     4201 ttaatactgg tgaagggaga aacatagcag acgcttgaag cgggttacta tgtcgtgccc
     4261 atttcaagcg ttttttgtta ttcatattag aagaaaggag gtaacaaaat gaagaaaaat
     4321 ctttatccag cagtcagtat ggcattcatt ttaattattt ggcagattgt tgtcatagtt
     4381 tggaaaatac ctgcctttat tttacccgga cctgctgctg tattttctgc attagcggca
     4441 gatgcacaag tattactttc ccattctgtc acgacattaa atgaagcagt gcttggtttg
     4501 gtaatagcta gcgttctttc ttttattact gccttggcaa tggattattg gaagttttta
     4561 gaaatgtctt tttatccgtt actagtgatt tcacaaatgt tgccaatcat ggtgttaggg
     4621 ccattactta ccctatggtt tggtttcggt atgcttccaa aagtgatcct tgttgtcttg
     4681 ataagctatt ttccgatcgt agtttctttt tcggatacat tgaggaaagt atcaaaagag
     4741 caaatcatct ttttgaaaac gatgggggca gatacaggga agatttatcg aatatataaa
     4801 ataccagcgg gtttatccgg cttcttttcc ggtttaaaag tggctgctac ttattgtgtc
     4861 agcggagcag tcgttggaga atggctaagc gctcaagcag gcttagggta ttacatgata
     4921 cgcgtaaaaa acagctacca gatcgataaa gtttttgctg cgatcatttg tgtcattcta
     4981 ttgagtttat tgctgaatgg cgcttgttca ttattgaaaa aagggtatta tcgtatgctt
     5041 tatatttttt aagagaaggg gatcaaatga aaaaattatg gcttttatta ccgctactgt
     5101 tgcttttatc cgcttgtggc actgcaaaag aaacaagtag caaacaagaa ataaaggatt
     5161 tgaaaaaagt gacacttgtt ttggattatg taccgaatac taatcatact ggcatctacc
     5221 tagcaaaaga aaaaggctat tataaagagg ctggtttaaa tgtccaaatc atcgaaccag
     5281 gagataattc gacaagtatt ggtctagtag gtgcggacaa agcacaattt ggtgtaagtt
     5341 atcaagaaga tgtcacttat gctcacgcag atggacagaa tataccagtc aaagcaattg
     5401 ctacagtgat caaacataat acttctggat tcgccaccct atcagacagt aacatccatt
     5461 caccaaaaga ttttgaagga aaaacatatg caggttggca aagtccaagt gaagaagctg
     5521 tcttaaaagc tgtgatggaa aaagacggcg gggacttttc aaaactgaca atggtaggaa
     5581 gcaatggaga agggccagaa agcttaggaa aatcctcaga tatccaatgg tactttgaag
     5641 gttgggatat gatcaaagca aaagaagcgg gtattgaact aaactatatc ccattgaaag
     5701 aattagatga acggttagat tactatactc cggtaattat tacgaatgat caactgatca
     5761 aaagtgatcc agaattggta cagtctttta tggatgccac gaaaaaaggc tatcaggaag
     5821 ctattaagga tccaaatgac agtgctaaac tgttgcaaaa atatgcaaaa gaaaatgatc
     5881 ggacgttttt agaagaatca caagcattct tgtcaaaaaa ttatacggat gatcctgaga
     5941 attggggatt gatggaagaa aaagtttggc gcaattatac agcttttatg caggaaaacg
     6001 gattgatcaa gcaagatgta ccttcgcaag aactattcac taatcagttt ataaaatagg
     6061 agtgatagat atgtcaatcc aaatcagcca cttgaatgta gtcattgaaa acctgaaaat
     6121 attagaagac atccatttca ctatccctaa agataccttt acatcgattg tcgcgccaag
     6181 cggagccggt aagtcaacat tgctgaaaac tttaacagga gtccagccta tgacttctgg
     6241 aacgatcaaa gtagacgatc aaaaagtaac tggtctccat acagcattta gttatatgcc
     6301 gcaagaagat atgttacttc cttggctgag cgtctatcaa aacgttacgt tatatcaaaa
     6361 aatcaatcat ctaacaatca atgaagaaca agtaagggat tatctggata tctttgggtt
     6421 aaacggctat gaacattttt tgccggaaca attatctggc gggatgaagc agcgaacggc
     6481 cttgttacga acaatcatga atccttcttc ttacttgctt cttgatgaac catttggagc
     6541 gttagatgct atgaccagag ggcagatgca agactggatg ttgaagctgc ctaaaaaagc
     6601 aaagcggact actttacttg tgacgcatga tatcgaagaa gcaatttatt tatcagacag
     6661 gattcttgtg ctttccgccc gtccggcaca tgtgattgct gagattcaag tgcctgaaaa
     6721 acgacggtca cgtgaatggc tactgcagca atcagagttg aagcaaacga tttatcagtt
     6781 attggcaggt gaattagatg ttaagtgatg ctcattgtca tttagatggg agtcagagtt
     6841 tagcactcct tcagcaggaa cacacgattt tgacgatcat caattgtgat tcgccagaag
     6901 aatggaagga aaacagacag cttgcagcaa gtaagactca agccttaagt tacggtatcc
     6961 atccttggaa agcagatagc tatacgtttg aacaagttga gccttttttg aaaaaagcaa
     7021 ggatcatcgg tgaaataggg ttagataata tttggacgaa tgtaccgatg actacacaaa
     7081 aaaaagtatt tgagcgacag cttgcttttg cagccataaa tgagaaacct gttgtactgc
     7141 acacaaaagg atgcgaaaaa gagatcttaa attatatcca agcttaccct aatcactatt
     7201 tgatccattg gtattcttct ttggactatc aacaagacta tattgattta ggctgttatt
     7261 tcagcattgg tcttgatttg aaaaagaatc cagcagtctg gcaactagct aaagcagtcc
     7321 caatcgacca cttacttatt gaaacggatg gactacatgc agcagagtgg gctttagggg
     7381 ggattttttc agaaaaagat tatgtctcac tgcttgaaga acagttaaag acaatcgctg
     7441 agatcaaaga gctatcagtt gaagaagtta aaaaaaatac ttatcaaaac ttggaacgtt
     7501 tcattagatt aggtaaataa aaaagagatg tgacacaact agtgtcgcac ctctttttgg
     7561 ctttctttgt ataaaagtaa actgtttgat taataaatga atcttagtac caaccgtttg
     7621 cttcccagaa tgctttcgcc gcttcccaag aaccataacg tgaagtaaca tattgttctg
     7681 ctactctttc ttggtttgca gcagagtagt caccatttaa gtaagaagaa tctaattggt
     7741 aacgtccgat gtaacgtccg ttcgttgctg tgtaagaacc gcttgattct ttttgtgcga
     7801 tccattcttt tgcagagctt gtgcttgctg gagtagcagc agtttctgtt acagcaggag
     7861 caggttgtgt ttcagcaaca ggcgctgctt gtttttccgt ttgaaccgtt tcttgtacaa
     7921 caggttgttc agcttggact ggtgcttctt gaacggctgc ttgaggttca gcagctgctt
     7981 gtgcagagcc ttctgttggg attgttaatt gttgtcctga gta
//
LOCUS       DADLIO010000101         7651 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.106, whole genome shotgun sequence.
ACCESSION   DADLIO010000101 DADLIO010000000
VERSION     DADLIO010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7651
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.106"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(<1..755)
                     /locus_tag="JOX41_002592"
     CDS             complement(<1..755)
                     /locus_tag="JOX41_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAY6450283.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLVIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQYKVSLLKSLKGLVKNRALLSIIGAAIFLLL"
     gene            complement(875..1522)
                     /gene="eda"
                     /locus_tag="JOX41_002593"
     CDS             complement(875..1522)
                     /gene="eda"
                     /locus_tag="JOX41_002593"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HAY6450284.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(1606..3033)
                     /gene="uxaC"
                     /locus_tag="JOX41_002594"
     CDS             complement(1606..3033)
                     /gene="uxaC"
                     /locus_tag="JOX41_002594"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HAY6450285.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLWYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(3107..4186)
                     /gene="uxuA"
                     /locus_tag="JOX41_002595"
     CDS             complement(3107..4186)
                     /gene="uxuA"
                     /locus_tag="JOX41_002595"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAY6450286.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(4189..5820)
                     /locus_tag="JOX41_002596"
     CDS             complement(4189..5820)
                     /locus_tag="JOX41_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HAY6450287.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            6124..6795
                     /locus_tag="JOX41_002597"
     CDS             6124..6795
                     /locus_tag="JOX41_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAY6450288.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKNI"
BASE COUNT         2477 a         1497 c         1036 g         2641 t
ORIGIN      
        1 aggagtaaga aaatagccgc accaattata gaaagtaatg ccctattttt aactaaccct
       61 tttaaagatt ttaacaatga aactttgtat tgagattggt caattcttac tcgttcagta
      121 gttagtttat aacatattaa ataacaaata agtgcacata tcgaaaatat tcccgcaaca
      181 attgtaaaag ttgatccacc acgaactatt tgagcgcctg aatcatctct tgtataaata
      241 aataatggtg ttaatacacc aatgaccaaa cttgctaaag tagctccaac atttcggaat
      301 gtcgatagca ttgttctttc ttctgtaata gaagtaatag ctgatgccat tgatccataa
      361 ggaatattta tagatgtgta aaaaatactc ccccataata tatacgtaac atacatgtat
      421 actaccttaa cgctcataga agctgaaatc atagaagttt gatacattaa aaaacttgct
      481 aaagcgactg gaccactcat tcttaaaatc cacggtttaa acttaccctg cttagttgct
      541 ttcgatctat caacaatacg ccccatagtt acatcagtaa ctgcatcgat aaatcttgct
      601 actaaaaata atgttccaac ggcagctccg cttatcccca atacttttgt ataaaagatc
      661 attaaaaaag aactagcaaa aatgaaagta aaatcgtttc caaaatctcc aaacatatat
      721 cctattttgt ctcttatacc aaattttctt tccatacaat tctctccctt ctgttgttaa
      781 gcgttttcat tctgatgaaa gtacgtacta tactctgaag cgtaaagagt cagtatttat
      841 tttttacatt tcagagtatt atttgttttt tctcctaata attctttatc tcataaaact
      901 tatctatata tttactagct actcgactta cttcttcaaa atcacctttt tcaacagaag
      961 ccaataaatt cccacctaca ccaactgcaa caactcctac ttcaaaccaa tcttctaagt
     1021 tctctatact tactccgcca gtaggcatta tatttacgtg tggtaatgga gcttgatagg
     1081 cttttacaat ggatggacca aaagcagaac ctgggaatag tttaatgata tctacgccag
     1141 cagtaagtgc ctcctttatc tcagtaattg tcatacaacc tggtaaataa ggaatttgat
     1201 ataaattaca aatctcagct gtttgtcgat caaaagatgg actaacgata tattctgccc
     1261 cagccataat tgcgatacga gcagtaaacg catctaaaac cgtaccggct ccgattatta
     1321 catctttttg atcagcatat tttttagcaa tttctttgat tatttcttca gcattaggaa
     1381 ctgtaaaagt tagttcaatc cctttaattc cacccgcaat aattgaattt attgctttaa
     1441 tggcctcatc cttatttttc ccacgtacaa ccgcaatgac tccagccgct tctaacttac
     1501 ttaaaatttc tacttttttc atatctatct ccttccttta tggatacata ctttgtctag
     1561 ctgtactaac ttacaaagaa taaatttaag cttttatttc aagtattatt ttctacttcc
     1621 gatttcaaaa aaattaaaat aattatacgc attacgataa caaatattct ccactatctg
     1681 actaagatac atttcatcat ctggaattcg gcctgcttta acccactcgc ttagtaattg
     1741 acataatact cgacgaaaat actcatggcg aggatagctt agaaaacttc gagaatcagt
     1801 caacatacct gtaaaattcg acaacaaact ttgttgtgcc atcgtagtca actgttgacg
     1861 cattccttca gctgtatcat tgaaccacca agcacatccc aattggattt tttgaatcat
     1921 acccccttgg aagctttgca ttgctgttgc tagtggaagc caatcagttg gatttaatga
     1981 atataaaatt gtttttggta agcacccact cttttcagcg gtatcgaaca atgctacaac
     2041 attttgtgtc aaactagctt gatcccccat cgaatcacca ccgacatcta ctccaatttg
     2101 ttcctttaat atacttgaat tatttcttaa agcatttaaa tgcatttgca tcgtccaacc
     2161 atatcttgta tactcagaca tcaaatgtaa ttgaatacct gtaacaaatt gtgcaatttc
     2221 tgataaatgg aaatccgttt ttcctgctaa agcttttatt aacagattgt cgagtatttt
     2281 ttcatctgct atttcataaa aataagtatt caaaccgtga tctgctaatc gacagccaat
     2341 ttgatgaaaa tgatccactc gttggctcaa tgcttgcttc aacccattaa agtctttgat
     2401 tggtatagcc gctgtttgac taagttttaa aatatagttc gaaaagcctg atgatttgat
     2461 actccagacc ttatctggac ggaaagtagg taataccttg aaagaattat cctgtttaga
     2521 aagctcagta tgataccaca agtcatctgt aggatcatcc gttgtacaga tggctttcac
     2581 atccatcatc tccaacaatt ctttcgggcg ataggaatcc gtttgaattt tttcgttagc
     2641 acgtcgccaa atttctggtg cattcttctc agaaattgtc aaatcaatat caaagtaacg
     2701 ttgtaattcc aaatgagacc attcaaaaat aggattacct ggcgccttct ccactgtttt
     2761 tacaaaagct aaaaattttt cataatcatc acctggacca ctgatcaact cttcttctat
     2821 accattagct cgcatcaatc gccatttata atgatctcca gctcctttat catttaacca
     2881 tacctgagtc aaattcttgt attgcttatt ttctagcaaa tatgctgggt ctaaatgaca
     2941 atgatagtcg ataattggtt ggtgttttgc aaatttatga aaaagtcttt tagctatttc
     3001 attctctaat aaaaagttct tatctaaaaa catatttaaa cactcctttc cttccgttag
     3061 tttttagaag agaaaatttt tcctctaaat aaactccctt atataattat ttactcgccc
     3121 ccttttcaag cgcttcccaa ataccattta aataaactgc acctagagct cggtcatata
     3181 atccataacc aggtctaccg gtttctcccc aaatcatccg accatgatct ggacgaatat
     3241 agccattaaa tccattatcg tacattgttt ttaatatctt atacatatct agagaaccat
     3301 attctgattt atgcggcgct tcgtaaaaat cgagtccatt gtcacttaaa tatttgatat
     3361 tacgaacatg tgcaaaagga atccgatccc gttgacaaaa ttcagataga atttcataga
     3421 catcattatc tggtcgttct gcaatacttc cagtacataa tgtaatacca ttagaaggag
     3481 aatccactac attacacaac caatctaaat cgtcacgatt tttaacaata cgaggtaatc
     3541 cgaaaatgga atatggtgga tcatctgggt gaactgccat tttaatccca acttcttcac
     3601 atgtcgggat aattgctttg agaaaatatg caaagttctc tcgtaatttc tcttcatcaa
     3661 cttctttata ggcttctaat aattgcttaa tttgtgataa ccgatgaggt tcccaacccg
     3721 gcaattcaaa attattagta gaattttcta cttctctaat aatttcctcc ggatcagtag
     3781 ggatattttt tgaaatatag gctaacgtag aagacccatc atctaaacga taatccaaat
     3841 ccgattttac ccaatcaaat actggcataa aattataaca gataacctca atcccaaatt
     3901 ctgccaaatt gcgaatcgtc tgtttataat tctcaatgta ttgatctcgt gttggtaaac
     3961 caattttgat atcatcatga acattaacac tctcaataac tttcaaggta agtccattgg
     4021 cttcgacttc atcttttaaa gatttaattc gttctctcgg ccaaacctct ccggctggta
     4081 tatccattaa tgttccaaca attcctttca ttgctgggat ctgacgaatt tcttgtagtg
     4141 agattttttc ttcatttgcc ccataccatc taaaagtcat ttccatagtt actttcctcc
     4201 aacttctgtt atatatttat tgattgtttt acgaactgct tgaggaccta ctagcatttc
     4261 gcaaaagatt ttttcagttt tctttcctac cccaacttga tataaatcta aaccaaagat
     4321 ttctttattt tctaaaattt cctgtaccgc acaatgaatc tttgaaggat cttgttcacc
     4381 taatttcaat actgataatt tatcctgcaa ctctaccaat aacggatcag gacttggcac
     4441 aaaattttcc ccttgatcat cgactgccag taaataacgt aaccaagcag caatagcgat
     4501 aggaataaat gttagatttt ctgcatttcc gtctttttcg acatactttt taattgtttc
     4561 accatagcga atcgctactt tttgagaagt atctgttgca attcgttgtg gtgtatctgg
     4621 aatataggga ttaggcaaac gtttattaat tacttcatca ataaattgtt ttggatcaat
     4681 aatgcctgga ttttcaacta ctggtaaacc ttctaaataa cctattcctt tgattaaacc
     4741 aaccaaatca tcatcctgca tctctgctga aattgattga tatcctagca gacaacctgt
     4801 tactgccaaa gcagtatgaa gtggattcaa gcttgtcgta accttcatga tgtctgcttt
     4861 atcaaccgtc tctctatctg tcataatcac accagccttt tccaatttag gccggccatt
     4921 tggaaaacta tcttcaataa ctaaataatg aactacctca gtattagtga aagcagcaat
     4981 attggtatgt ttttttgtgt gaatgatatc taaatcctcg agccccatca tcaatagatc
     5041 ttcctttaca ttctctgaag gatttggcgt aattcgatca atcatactcc aaggaaaagt
     5101 cactttttct ttatccttta aataagcaat aaatttttca gaaacatatc cttctttttg
     5161 ccaagcttct gcaatcgtaa aaatactatc ttgaaaacgt tgaccattct gtgagaaatt
     5221 atcagtagaa accatcgcaa tcggcaactc tccagcatta aatctgctat ataacaagga
     5281 tgttacaata ctcatcgtat gttgaggatt gctaggtcca gatttgatat cagctttgac
     5341 taccgaaaag aattgccctt tagaatcttt taaactgtaa cctttttcag taatagtaaa
     5401 cgttgtaaac tgtaatttag gatcttcaaa atatttaacc actctttgat agtccgctat
     5461 attcttcgga ttgcaatata aactatcagc cgttactgcc aaaagtcttt ttttgagttc
     5521 accatctcca ctcataacaa tttccaaaat gtcattgtta tagtcatgat aagctttttc
     5581 cactacttct tcatcaaatg tttcacacac aactactcct gtttctaatt cattttgatc
     5641 tgctaagcat tgagcaattt ctgcatgaaa tcctcgataa agatttcctc caccaaaatg
     5701 aagccatact ggatgttgct ggccttcttg cttaacttct ttgacatcaa aacacggcag
     5761 tagaatctgc atttcattga attcttcgat agaattttgc caatttttaa tcgaaaccat
     5821 aattaacctc ctcaaactga tatgttagtt ttgatacatt ttatatttta aaacccattg
     5881 taaccgttgt caatataaaa agggaataaa cttgcttttt tctaccatat cagaatgatt
     5941 gtatttttta ttcagaaaaa taaaatactc cttctttttg gactgatttt atcgaaactt
     6001 attttttctt tttttcatgt attcttttat ttttataact agtgtattac ttcaaaattt
     6061 gatattatat ggcatgaaca gaattaaaat atcagttaaa ataaaagtta aggagcattg
     6121 tgtatgacaa ttaaaactag tctccaaaat caagcttacc aatctattcg ccgacaaatt
     6181 atctatgctg acttagaacc tggaaaaaaa gtatcagaaa aaaaattaga agaaacactt
     6241 tctattggtc gtacaccaat acgtgaagca ctgattcaac tccgacaaca aggtcttgtt
     6301 gatacaattc ctcaaagcgg aaattatatc tcattaattg atttagattc ggccaaaaat
     6361 gctcgatttg tcagagaaca tttggaacga caaattatgt tagagtgttg tgccaaaatg
     6421 aataaccaaa aaaaacggat tttagaaact ataatttcag aacaagaaaa agctgttagt
     6481 caaaaaaatg ctcgtagttt ttttcataat gataatttat tccataaagc ttgttttgaa
     6541 attgcagagc gagaagaagt atggcaatgg ttagaaaata acaatacaca cttagaacga
     6601 tttcgatggc tacgagtaaa aacggaagga ttaaagtggg aaaaaattat ggaacaacat
     6661 tatcaactat ttgaggcatt aacaaaacaa gatccagaag aagctaactt tctaacatcg
     6721 ttgcatcttc atttaatgct taatgagcaa aatattgttt tagctactca tccaaaatat
     6781 ttcaaaaata tataactttt aactcttttt aaattaaatg gttgttctga tcagaaaaat
     6841 atcgcttgtt ttcttattat gtaatatatt tcataaacta ttctgcataa caactattgt
     6901 ttgtactttt tacattggat aactaattat gactgctgat aacttttgat attaaactag
     6961 tatctccaat acaaataaaa aatagatatc ttgttcatca aaattagttc gtggatactt
     7021 accttcattt acatcattca gcggtttccc attttctttt attctattat ttcattttct
     7081 aatagacttg gcttcatttc gcaatacttt ttttcaatag gcatcaaatt ggtgttgttt
     7141 agatatttag ttgtagtttt gtgacatgat aagtatgctc ctttttctct tttccactaa
     7201 tacaacgatc aaagggtgct tttttcaaaa aactagaaaa atcaaaataa gattcgtatt
     7261 ttgattctat atatcctgtt tcaactacat cttatatttc acaatagaat aaatagcctt
     7321 ttgcatagct gcttaactta taagaaattg caatttactt cttcaaagtg aaaacgaata
     7381 tgagtaaaat aaaattattc ttcttacaga taattaaaaa tagcgcgtaa caaaaatcgg
     7441 cattcaatca cataattagg attgatgccg attacttata ttctacgtat agttttagta
     7501 ttcttatttt ttatcaccag taaccaattg agaacagccc taaagcagaa tagtctttta
     7561 tctcaaaacg cttaatttca ggcttaggaa tatgaataat cttttgagta tattctttct
     7621 cttttaatct tactgaagaa ataccactgc c
//
LOCUS       DADLIO010000102         7537 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.107, whole genome shotgun sequence.
ACCESSION   DADLIO010000102 DADLIO010000000
VERSION     DADLIO010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7537
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.107"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            <1..848
                     /locus_tag="JOX41_002598"
     CDS             <1..848
                     /locus_tag="JOX41_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type VI secretion protein ImpB"
                     /protein_id="HAY6450289.1"
                     /translation="TVGVGDNPLLAKLALDNEAKHNDGFLAEWTYQNVPDKVWNIPEM
                     TDLWGIGSRMKKRLNQIGIMSIKDLANWNPYTIKSHLGVIGLQLYFHANGIDRTDIAI
                     PPEPTKEKSYGNSQVLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLYIGTS
                     ILETRPGFSHQMKIPITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQL
                     DLFSDPQKQIDEENLDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAG
                     GLKND"
     gene            841..1191
                     /locus_tag="JOX41_002599"
     CDS             841..1191
                     /locus_tag="JOX41_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450290.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEKIDADNEQRANQNLAKEQMTTE
                     EVAEVLNAAVIKNRSVCIQKEERNAEGYYPEDIVSKILGSDELGIYVGKNKVHYDEIR
                     HIEFYQDNKWGRLE"
     gene            1173..1358
                     /locus_tag="JOX41_002600"
     CDS             1173..1358
                     /locus_tag="JOX41_002600"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450291.1"
                     /translation="MGSIRMNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSF
                     YVEAAAGYHKYEYYIGY"
     gene            complement(2262..2537)
                     /locus_tag="JOX41_002601"
     CDS             complement(2262..2537)
                     /locus_tag="JOX41_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgO"
                     /protein_id="HAY6450292.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(2509..3462)
                     /locus_tag="JOX41_002602"
     CDS             complement(2509..3462)
                     /locus_tag="JOX41_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAY6450293.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            4074..5567
                     /locus_tag="JOX41_002603"
     CDS             4074..5567
                     /locus_tag="JOX41_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepR"
                     /protein_id="HAY6450294.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            5702..5998
                     /locus_tag="JOX41_002604"
     CDS             5702..5998
                     /locus_tag="JOX41_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HAY6450295.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
     gene            6099..6950
                     /locus_tag="JOX41_002605"
     CDS             6099..6950
                     /locus_tag="JOX41_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450296.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            6971..7183
                     /locus_tag="JOX41_002606"
     CDS             6971..7183
                     /locus_tag="JOX41_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450297.1"
                     /translation="MIPLYRIVLIVGMELKTLKKEQLFKVKERHNQLLCSKTGTMNIE
                     YRTEYLELTNQTDFLLIRKQQEQEKN"
BASE COUNT         2612 a         1175 c         1419 g         2331 t
ORIGIN      
        1 ctacagtagg tgtcggagat aatcccttat tagctaaact tgctttagac aatgaagcaa
       61 aacataatga tggattcctt gctgaatgga cgtatcaaaa tgttcctgat aaagtatgga
      121 atattcctga aatgacagac ctttggggta ttggatctcg aatgaaaaaa agactcaacc
      181 aaattggtat catgagtatt aaagacttag ctaattggaa tccatacact attaagagcc
      241 atttaggtgt gattggctta cagctgtatt ttcatgcgaa cgggatcgat cgaacagata
      301 tagcgatccc accagaaccg acaaaggaaa aatcatatgg taattcacaa gtgttaccac
      361 gagattatac caggagaaat gaaatcgaac tggtggtaaa agaaatggcg gaacaagtag
      421 ctattcgtat caggcaacat aactgtaaaa caggttgtgt ccatttatac attggcacgt
      481 cgatcttaga aacgagacca ggtttttcac accagatgaa gatccctata acagataata
      541 caaaggaatt gcagaattac tgtcttttct tgtttgataa gtattatgaa ggacaagaag
      601 taaggcacgt tggaataacc tatagcaagc ttgtgtacac tgattcgctt cagctggatt
      661 tatttagtga tccacaaaag caaattgacg aagaaaattt agataaaatt attgacaaga
      721 ttcggcaaaa atatggtttt acgtcgattg tacatgcttc ttctatgtta gaaggcgctc
      781 gtagtattac tagaagtaca ttggttggtg gccatgcagg cggcgcagga gggcttaaaa
      841 atgattgatt ataatgatcg tggacgttta aagtgggcag gtttttattt atctgatcat
      901 actgaaaaaa ttgatgccga caatgaacaa cgagccaatc aaaatttggc aaaagaacaa
      961 atgacgactg aagaggttgc ggaagtattg aacgctgcag tcataaaaaa tagatcagta
     1021 tgtattcaaa aagaagaacg aaacgctgaa ggatactatc cagaagatat tgttagcaag
     1081 atcttaggta gtgatgagct ggggatctac gttggaaaaa acaaagttca ctacgacgaa
     1141 atacgtcata tcgaatttta ccaggataat aaatggggtc gattagaatg aacattatcc
     1201 agcaatatga gctaaagtat ataacctttg atcagctatc agaagagatt tggggttatg
     1261 gccagcgttt gataaatgag gttggtgttg aacgcttctc tttctatgta gaagctgcag
     1321 caggatacca taaatacgaa tactatattg gctattaaag tgcaataaaa ttatatttct
     1381 tttatgtttt acattttgta tcaattctga taaaattacc tataggtaat taaaaaatat
     1441 aaaaaaacta gttacaacct taggacgttg taactagctt gaagcatact agagctaact
     1501 aaaatagcac tagaaagcaa tgttaaaccc gtccaacaaa cttgatttaa cattgagacc
     1561 agcttattca gctaaatata gttgaataag cttcttttgt tttaaaaaaa caaaaggtgt
     1621 actacgaata acgcaagtaa aagaaatact attacaacca gtaggctaca agtaagtatt
     1681 actaaacatt gcgtagttag aacctttgct ctattgtcta aagccacaaa attagagatc
     1741 agctttatga tgctaagagc gagctgcatc catgcggaca taggttcttt tgacactatt
     1801 aattctcctt tttaggataa gggaaattgc tagtagtttt ttcattagca ccatccccct
     1861 tcatttgatt gagtctagtg ctgctgtgat agtttgctgt ttaatatgct tacattctta
     1921 ttataacata aatgaaacaa acacatggtt agaggtcgta tcaatcaaaa tagtgtctca
     1981 caaacgattt attacttact cctgctgact aacggactgt tcttcagtaa ctgtaactat
     2041 atgtttgtta aaaccaccat tacctgtaga taaaaaccaa tatatttact atactcacta
     2101 tattaaatat atttagtata gtaaaaacta gaaacaataa aatttgtgaa tgttgtatac
     2161 ccccaaacaa tacacatatt ttgaaggatt aggattaata aagctaaaaa tatagtaagt
     2221 atactaaata tatttactat atctagtata cttactatat tttaatcttt tgatcgtcta
     2281 ttatatataa tccgttcctc gtcgtttaaa gtatcaacat aggcgtccat tgcaagtttg
     2341 actatttcat acataggaat atcttttgca taactaagat cccgaatggt ttttagtacg
     2401 ggaggatcta cttgaactgg ttttctttct ttcgcagtgt actttcgttc ccctaactcg
     2461 acattaatat catctttaat tgaaatatct tcagcaccaa ttttcttctt atctttgttc
     2521 gttggtaata atgccattta gtttaatctc ctttccaaga ggtaggatat gattggccat
     2581 tgagtcagca tatttaggtg tataatcaaa tccttcaata tcaccatgtt gttcatagta
     2641 ttcaattctt tcttctaatt ctgtaaagat gtctgcaaaa atagcccacc atcttcgatc
     2701 tacataatca tttaattgga taccattctc accatacatt tctaaccgat ccgagccttt
     2761 aacaatgctt ttaaaaatgt ttgattcacc atacttatca attgtttttt gatagtttgc
     2821 gtgttgagag gaacgtcgca ctgagaaaag aacaggcaaa attccaatga tttgaagatg
     2881 agactcttca aaattcgtga caatcggaac taaaacttta ttaataaaat cttctgttcc
     2941 ttccattgcg taccgtttta attcttgcat tgcaataata taatctgcag cagttaagaa
     3001 tgcacgaacc acattatctg ttgatggtgg gcagtcgata aagatataat cgaaattttt
     3061 tctcaattct tctaaaggtt taatgaaggc caatgatctc ttacgacgat caggatattt
     3121 ttcggacaag tattcattaa gttcttcaga tccaggagag ccagccataa tatataaatg
     3181 tggacttact tgagtaatac ctgaaaccca gtcccctttt ttgattgctg cagacatgga
     3241 tcgatcaaag ctagtaattt gatacgttga tccaatgttg gaagtagtat ttctttgttg
     3301 gtcataatca attagcaaca cgtctttttc aaaaagttga ctagaaacaa tcgctaataa
     3361 atcattgtct gtagtcttac caatgccgcc ttttctacct gtaagcatta caacttttcc
     3421 tagtttatct gatgttttaa atgcagtccg taagttttcc atagttccct ccaatttcct
     3481 atactaaata tatttagtat acttcatata cttaatatat tcgatatatc taatatactc
     3541 caaattgata agaattcaga ctttataagg aatatagtgg atatactaaa tatatttgct
     3601 atattcagta tatcagatat attcaaaatg tcaaaatata tttgtgcgtt ttgcgttgac
     3661 aatttagagt gaaaagaggt aaacttaatt ctatagaaac cacagataat tcactattta
     3721 caaagtagca aaagcagtgg tactctttaa acagaaaaat tacataaaaa aaagagacgg
     3781 aaataattga ttttagcaga atcaattatt tctgaatcac atggttagga catgtgttca
     3841 cgctcgtctc aagaatatgt aagtagctac caactactta tattaaaagt tgatcggata
     3901 ccttttccga ttgcctttat tctaccaaaa aaaggcgagc aactcaacag aagaacgttt
     3961 atttagtgta cttaaattaa atattcttaa acactgaaga gagaacacat actatggctg
     4021 agattaaagc taaactgtgt tctctttttg tttgagaaag gacgttacaa tcgatgttga
     4081 gcgaaattta ttcagctatt cttaaaaacg gcttacgtac atacaaatat cgaaacagca
     4141 ccatgaaacc tgcaggtcat attgattcca gtaggagtgg tgctatcttt gcgtaccgta
     4201 gcaagcaatt aatgaatgtt gggcgtggta tggtcattac ttcggaagaa gctattttag
     4261 agaacgaaaa gaaactaacg cattggacac ctaataccta tcgctttggt acttatgcgg
     4321 atgattatcg aacagtggtt aaaggtcatt ctgagaaaaa cttaagtcaa atcaacacat
     4381 ttgtagttga tatcgattca aaagagaacc atcaaggcga aattatttta gcctgtttag
     4441 atcaagtggg ctacatgcca acgctaattt tagaatcaga tcatggttat caagtttatt
     4501 ttgtactaaa gacaccaggc tatgtcacaa agaaaagcaa tttcaaggtg atcgatgtag
     4561 caaaaaaaat ttcaaaaaca attcgtctac agttggctga aaaattgtcc ggagtggatc
     4621 taggatgtaa ccacttcgga attgctcgat tcccacaaga aaataatatt gtttttaaag
     4681 aaatgaacta tcagtattct tttgctgact ggattcaatg gtcgatgaag cttgaatcag
     4741 atcaaaaaac aaaagaagat cgagaacgaa aactaattgt ctttcctgag aaaaaagaaa
     4801 ttcgtcaagt agatgaaccg tggttcgata tgttacttca taaagcaaac atcgtcggcg
     4861 gagaaggacg tcttggtcga aataatgtga ttttcacgct ttctttagct tattactctt
     4921 caggttatgc attggatact tgcgaataca atatgttcac attcaacgaa cggttacagg
     4981 aaccgctatc tgaagcagaa ttagtaaaga ttgtacgtag tgcttattct ggtaattatc
     5041 aagcagcaag cagagaattc attattgaat tgtgccagca atgggtttca ccaaccttaa
     5101 aaaataatga tctgttcatt caacgacgtg gctggtggaa atttaaaaag ccacgagatc
     5161 aaagaaaata tagtcataaa aatgaatgga aagaagatct attggcttat ctaagcgaaa
     5221 aaagtcttgc tagtgagcct tatttgaacc tgtcaaaaaa agaattggct tcacaactaa
     5281 cgatgcccaa gcgaacactt gataagatct taaatgagtt acgagaggag aataaagtct
     5341 tctacaaggt aacacgagga agaaatggcg gaatgatcat tgcttcagtc aaaacgttgt
     5401 tcgcgagggt tattcaacta agtaaagaaa agagactaga ttattcaaca aggatcacag
     5461 aggtatttgg actcaacgag agcttagtag aagagacatt tagacaatta tcaaccccct
     5521 tgaaccctct taaagaagtg aatctttttg aagtagatac aggttgaaaa ataaaaggtg
     5581 caaattgccc tatacaatat atctatgata cttctgtagg tgttgctccc tttgcctagc
     5641 tacgtgtagg tggtatactt ataactgcgt atgcagtctt atgtatcatg gaggaagttg
     5701 tatgtcgtta aaaaattatg tctattcaca tcctgttaat gtgtttatca ttggtcgttt
     5761 gggattatct gtggaagtgt tctgtgagct ttatggtttt aagcagggga ctttgtcttc
     5821 ttgggttacc agggaaaaaa cagttgcttc tttgccgatt gagtttcttc atgggttgtc
     5881 cttagcttct ggggagacta tggatcaggt atatgattgt ttgtgtgtgt tagagcagga
     5941 gtatattgag tataaaatag ctaacgagtt aagaaaaagg aagaagtata tccagtagta
     6001 gtttttattt acttaaaaaa ttggttcatt gagcaaccta tcgctgctaa agtagcaaag
     6061 gaaaacgtta aaggaaagaa tttagggaag aaatcgaaat gaaatcggac gactggattg
     6121 aacacacctg gcttcctctg aaaagaaata gcaaacgaaa gaaattttgg gtattgcaat
     6181 tatggccatt aggaaaactt tgtagttacg gggcacgact tattcttgat ttaaccgttt
     6241 actcgattgg agtatttgga acggcttatt acttgataaa tgatcccaat aggattgcag
     6301 catcagacat ttttacagtg ctaatgacgt tgatttttgt catgctattg tctattttta
     6361 ctcaattagt catgcaattt accaggcaaa aattaacagc aggaaaactt ttcaaaagcc
     6421 tattcgattt aattgttgta aatgcaattc tagcgacttt aataaaacaa attgaacaat
     6481 ctggaagaac aacaaaagga gtgaaggatt ttttattgac gtttattcac tttgtaaatg
     6541 gacacatgta tttgtttgaa gtgggtatta ttctcttttt tgtcgggtat gtatccacga
     6601 aacttattaa acgttcaatt gaaaaagaaa ttgaaattga cctgattccg acacttcttg
     6661 gttatgagta caatgttgat tttggaagat atgacgaatt gatcaatacg gatatcgttc
     6721 acacgagtat ccatgaatct actgttaagg gcatcagatc tattttaaaa aatggccagg
     6781 aaatgaaagc aatagatcga agaaaagaga tctacaattt ttatgaagtc gaagcaagcc
     6841 tacgatatgg catcggaaaa ttgtggttag atggaagtaa tattcgtcaa aacaaaccat
     6901 acattttttg gaacagtagt gatttagaac ttccaatgaa agataaataa ttatggagaa
     6961 tcgtttgaaa atgattcctc tatacaggat tgtgcttata gttggcatgg agttaaaaac
     7021 cttaaagaag gagcagttat tcaaagtgaa agaacgtcat aatcagttac tatgtagtaa
     7081 aacgggtacg atgaacattg aataccgaac agaatattta gaattaacga atcaaactga
     7141 ttttttgttg attcgaaagc aacaagagca agaaaaaaat taatggctac ttatagccaa
     7201 ttgattgatg aatgggaaca attcaaggaa tctaaaattc cagaacgtct ctaaaagcct
     7261 ttatttgtaa agagcataag gaaacgtggg aacacttttt aaaaaaagtg ttccaatagg
     7321 ctgtgcctat tacgtttctc aaaaataaat gtgggaacaa aatatttaaa aataggatag
     7381 tgaaaggata gtgaaggata gtaaaaggag ggtagtagga tagcaaaaag gataggctcc
     7441 ttttcgctat cctttttaaa ttggaggaat taatatggaa gtaagaataa gaaatgtgga
     7501 tgagaaaatc gtaagagaaa ttgatcgaag atgtgac
//
LOCUS       DADLIO010000103         7474 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.108, whole genome shotgun sequence.
ACCESSION   DADLIO010000103 DADLIO010000000
VERSION     DADLIO010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7474
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.108"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            275..1753
                     /locus_tag="JOX41_002607"
     CDS             275..1753
                     /locus_tag="JOX41_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAY6450298.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            2030..4090
                     /locus_tag="JOX41_002608"
     CDS             2030..4090
                     /locus_tag="JOX41_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450299.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            4173..4742
                     /locus_tag="JOX41_002609"
     CDS             4173..4742
                     /locus_tag="JOX41_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAY6450300.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(4917..5723)
                     /locus_tag="JOX41_002610"
     CDS             complement(4917..5723)
                     /locus_tag="JOX41_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450301.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            5861..7375
                     /locus_tag="JOX41_002611"
     CDS             5861..7375
                     /locus_tag="JOX41_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HAY6450302.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
BASE COUNT         2683 a         1226 c         1459 g         2106 t
ORIGIN      
        1 taaaagagca ggacggtggc cgtcctgctc ttttttgtgg ttgtttacgc aaatggcgca
       61 aatcttgtac attttaacac aataaaacaa aaaatataga atatttcctc ataaattttt
      121 ccattttttg caatattctc aaaaaaaaga taaaaaatga gaataactga tgaaaaaaca
      181 agcataatcc atcataaaat cagtataggt gaaaagatga actttcatct gcatatcaag
      241 taattggtat gaggcatttt ttgaggtgta ggatatgaag ttggattacc ttatagaaga
      301 ggaagataga gaaaaactgc tgctagctag atatttagaa tttgagaaaa agaattatgt
      361 agtgctgcct aagttatatg aaacattagg tttgtctaaa tttaaaacaa gaaattatat
      421 catagaatta aataaagaat ttactgaatt caaaacaaag ccagagatcc aaatttcaga
      481 agaagcagag atccatgtcg aacgtctgaa tttgacggat atcaaaaatt taagaagaat
      541 ctactttcaa cgatcaaaaa ttgctcgact gttaacggag atcgtggatt caaaagtaac
      601 gatcgaaaaa tttgcagaga atcatttttt aagcatatca agagcctatg taaaaagaag
      661 agaattagtc tcttttcttg aacagcatca aataaagtta aagaaaaaca tattagttgg
      721 ggaagaaata aacatacgga acgtattatt tggggtatat ttcggggtct ttaatggttt
      781 ttctatgcca tttagagaaa gcgtcatgaa tgaagcaaag agtatcgtgc aatattttga
      841 atatctgttc aatttaaaac tgtctgcaac aaaacgaatc aaattcaatt tgctaaccac
      901 tattagtttg ttgagggcct atgggaatca accaatcgga aaacgtttct tttcagatga
      961 atactttaag agctcagaag gaatgaagat catcaaggat ttatcacata tttcttttct
     1021 tcatatccct aaagagcaga tcattgatga gatttcttat atcatgttgt ttttgatcac
     1081 ggaagaagaa tttgaattag atggcgcatt tggacttgcg gaagctcatt ttcatgatat
     1141 ccacatgatt agtcaaaaaa tgtcagtgga attgattgat caattaccat tttcgattga
     1201 aatctctgaa gaagaaagac tatatatacg aaaagaactt cgtatgggta tgatgcatgt
     1261 caatcgaaaa aattggatat tcgactttga gatgactagc tttacgtcta aaaagcagct
     1321 acagtttttc ttcgagacgt atccaatatt cagtacagca atccaaaagg tcatacaaga
     1381 gaataaacgc tatttcttgg gaaaagatga acgtttcatg attcgcttat tttatgatta
     1441 tctcttttta ttggtcggta tttgtccggt atcatatttt gaagcaccga ttcatgtctg
     1501 tattgatttt tcgcaaggat ctgcttatac cgattacatt atttctcaag tgaaaggatt
     1561 taaaaattac aatattgtga ttgagagtcg aatcacttct cgtacgaata tttatttatc
     1621 tgattgttta cttgaaaaat ttaataaaga acagataatt tggaaaaatc caccgactcc
     1681 agatgactgg gaatattttg gaaataccat catcagagaa aaaaatagac atttaactga
     1741 aaaaatcagc tagtatttat ggatggcagc tttgtctcac atatttatta gctgatttat
     1801 gtttttttca aagaaaaggt aactagatat aactagatat aactagatat attacttaac
     1861 aaaattaaaa agtacataag ttattattcc gattttcttg aaacaataaa aaatcaaaaa
     1921 aaatactctc ctaatagtcc atcttctttt gattttattt atataatgaa atcatcttat
     1981 gaaaattact acttcatgtt tagacaagag tagggaggac taagaataaa tgtgttcaaa
     2041 aagacgttca aaacaactaa ataaacacgc ttgtcgttta gataaggaac ggtcgtgttc
     2101 tgaaaaacac tacgttaagt ttatgatgcg cacgatgctg atcagtttat ctgtaggtgt
     2161 ctatatgcat gtacccgttc aggcaacgac acaaaccatc aaggtcgtac gtacctctgt
     2221 ttctgagacc actgattccc ctatcactat tactcatact ttcactgatg caaatggaaa
     2281 acagctactt cctgcattga cttcctataa taaagtcagt tatcctccaa cgataaacca
     2341 ctactggtta attcctaaca aaacattatg gacatcggaa accggaagca gtgtgccgct
     2401 ttctatcttt tccgatatga ctgatcctac aaaaggtgat cagttaaaac agatcactga
     2461 tattttgaat catgctttga cagatataaa ggacggtgga agcgcacaag tttcttatgt
     2521 atatgaaaaa gattattcac agtttgaaag aaagaaaatc gatgttctgg cagggacaaa
     2581 agtttcgata tctgatctgg tagaaaggct gaagaacgca gatggaacac aaggagatat
     2641 gtccaaagta atttcaaaca atgggaatat cgtggatacg actaatacag gaacatctac
     2701 tatttccttg tcctattttg atccaattgc tttaaaaaca atgactgcat ctgctgtgat
     2761 ccatgttcgt gctgatcaaa cagctatcaa aggaaaagat cttcacttaa gaacaggaga
     2821 gagttacgcc cctaaagatc ttgttgaata tgtaacaaaa agcgatggaa cttcaggaaa
     2881 taaagaagaa atcaaaatga acgggacagt agatactaca actccgggag aatatcccgt
     2941 tgtattaact tatatagact cgaaaacatc aaatgtggca gaaacaacag ctgtagttta
     3001 tgtagaagca tctgctgctt catcgactgt catcactcat tttatagata gtcaaacaaa
     3061 taaagaactt caagcagaaa cacatatgag tagtgtaaat cgtattcctg atttgcgcct
     3121 acctgctgaa ttttctgatc gagtgccaaa tatagattta tcgacttatg aacaaaatgg
     3181 gaaagtcact tctatttctg attggatgca agcaaacgga ttagacagaa aaagtcactg
     3241 gtcggagatc cttgaagtac ttcactcaga actgatgaat aataggaagc aatcaggagg
     3301 ggaaattacc tttacttatg tttatatacc agacaatcgt tcattagaag gtcatgatct
     3361 tattgttcat ccaaacgaaa aaataaacaa agaagagttg atccaatcag caacaaattc
     3421 cttaggtaaa cccgtaccgt taaaggatgt atcggttaca atcaatgaag taccattgga
     3481 ggatggttat ttgaccaaac aaacaggtga ttttacgatt atgtatagtt atcatgaccc
     3541 gtattcactc caagaactcc atgctcagtc actattacat gttttaccat taaacaaaca
     3601 gatagatcaa aaagaacaaa aaagacaaga agaaagcttg tcagaaaaaa aacaacaaat
     3661 ggctcatgca gtttctccaa cagggaaagt aaaacaaaca agaagcctag agttagcaag
     3721 aatatctaga aaaatctcag aatctaataa aacgataagg caagaagctc atttggcccc
     3781 acaagtttct ggattggaaa atgaaatttt agagcctaaa ataaaacaac aatcagaaaa
     3841 agaatttgtt gctaaacagt cggaagatca gaaggaatca gatgaccaga aggaaacgaa
     3901 gaaaaaacgc ttgtcaacta ttgattccac cgatgagcat ctgcagccgc aagtaccact
     3961 tcctagtccg ggaacacccg cacctggtgg aggtattcct tcttctgctt taggagattt
     4021 catgcgaggt atggcaggaa catgggtata cgctaatcga aatgaatttg acgcagatga
     4081 ctggttctga tttatatctc tatctgttat agtcaaataa gtagctgagt catatgttat
     4141 ttggcataat ggagacgagg agggatagaa aaatgttaga taaaacgtta ccttacgcag
     4201 aaatctggat gacaagacca cttcaacaaa atgttccaat cacgccttta gcggaaggtt
     4261 ttgaatttcg attttatcaa aaagaagatg aatctgcttg ggcggagatt gagacttccg
     4321 ttggggaatt tcaaacgaca gatgaagcac ttgagtattt tcaacaaaac tttgctcctt
     4381 atcctgaaga acttgaaaga aggatgtttt ttgtagagac aaaaaaagga gaaaaagtag
     4441 caacctgtac cgcttggcga aaaaaatcaa gagagcaagt gtatccggtt tttcattggt
     4501 tagcagtgaa accagattac caaggaaaag ggctcgcaaa agcattgact gccagagtct
     4561 tgcaagaatt tcctaccctc catacggacg gaccaatcta tcttcacaca cagacatgga
     4621 gccatcaggc gattgctctt tataaaaaaa tgggttttac ttttattgct gaaaatctag
     4681 acggcacacc taatccagat tatgaaaaag ttatgcaggt tttaagtaaa ttagataaat
     4741 aacgaaatgg tgaaataagt cctcagtatt gggataaaaa acgaaatagt cattcctcat
     4801 atcttacttt tttgagttaa tactatcgga taactaatgg catgccatac attcaaaaaa
     4861 gaaggggcag tgacaaaagt attgtcactg ccccttctct tgttttttag catgttttat
     4921 cgtttgattt ttttaggaat aaaattcttg atgaacgtaa atttttggta atcgtttcga
     4981 ctatagaggt aaccaaatac actgaaaaca actgctccaa taaaattaac aaataaatcc
     5041 ttcatagtat ccatgattcc cacgtctaag taaccatttt ggatgattgt tttatctgtt
     5101 ttaccatctg cattttgact ttcaatgatt gtccgagtga tatctggaac atgatagaca
     5161 gtgtttccgt ctttacttaa ctccacacta ttgatttgct ggatgatcgt atctttttgc
     5221 atatcgaatt gcagtaattt atctgctgaa aattccacaa actcccacat aacaccaact
     5281 gtcatcgaaa aacagaagga aacaactgct agtaataaag gagtcaagtt catggttttt
     5341 gtatttttat tgagcaaata aacaagggaa aagccgacac ccccagctaa aaatccgctg
     5401 aatgcatgta gaaaagtatc ccacattgaa aaatagccat aaaaatcact taactctcct
     5461 aaaactgttg aactaaaaat aaaagataac aaaatgattt ctagcatatt tggaatctgt
     5521 atctttaata tcttttccag aaaataaggg atttcaaata aaattaatgt cagtaataaa
     5581 agcattgtat ttccccagtg ttggttccag acctgatcca ctagcataat aacgacgatg
     5641 atacgtaata aaatatagat tccgtttgtg attctacctg cagtttttgt actgttcgta
     5701 aaaaaggttt tcaaatgatt cataaaataa ctccttcatg tatatcctta attatactaa
     5761 gaagcgtgtg tttaccaaag ctatatgact taaagaaaaa cagagttgat attgtgaaaa
     5821 aaatcactta atatagtata aggagaaaag ggggatacaa atgaaaaaat tagttgctgg
     5881 tttattaaca gccgttgcac ttcttgctat gagcgcatgc ggcgcagatc agaaaaatac
     5941 agcgcagaca agttctagta cgaaggaatc tgccgaagta tcatcaggcg cttctgaaca
     6001 agtatataca gatccaaaag aaatgaaaga atcttatgat gtcgtgatta ttggagctgg
     6061 tggtgcaggg atggcagcag ctatcgaagc aaaagatgct gggttgaatc cagtaatttt
     6121 ggaaaagatg cctgttgccg gaggaaacac atctaaatca tcaagcggta tgaatgcttc
     6181 agaaacaaaa tttcaaaaag aagaaggaat caaagactcg aatgatgcct tctatgaaga
     6241 aacgctaaaa ggtggtggag gaacgaatga taaagaaatg cttcgatact ttgtcgatca
     6301 ctctgctgat gcggtcgatt ggctagatca aaacggtatc aaactggaca acttaacgat
     6361 cactggaggg atgagtgaaa agaggacaca tcgtccgtct gatggctcgg ctattggtgg
     6421 atacttagtg gaggggttat tgaataacgt ccatgagcgg gaaatcccta tttttgtcaa
     6481 cgcagatgtg acagacatta agaaaaatgg ggaaacggtc aatgaagtga ctgtacatgt
     6541 tcaaggagaa gaaccaaaag aggtcaccgg aaaagcaatc gtagttacca caggcggttt
     6601 tggtgccagc aaagaattta ttgaaaaata tcgtcccgat ttagctgatt atattacgac
     6661 aaatcaagaa ggatcaactg gagatggtat caccatgatt gaaaaattag gtggacaaac
     6721 cgttgatatg gataaaatac aaattcatcc aactgtgcag caggatgagg gggtcttgat
     6781 tggtgaggtt gttcgcggag aaggagcaat cttggtcgat caagagggga aaagatttgt
     6841 caatgaaatg gatacaaggg ataaagtatc tgcagcaatt acagcattgc ctgaaaaatc
     6901 agcttatttg atttttgacc aaggcgtgcg tgatcgtgcc acagctattg aattttatga
     6961 ccaaaaagga tatgtcacaa ctggaaagac aatggaagaa ttagcagaaa aaatcgattt
     7021 accaaaagaa acactagcaa aaacagttga tggatggaat acggatgttg cggagaaaaa
     7081 agatgctcaa ttcaaccgtg ccacagccat ggaacatgac ttatcgtctc cgaattatta
     7141 tgcgatcaaa atcgcaccag gaatccatta cacgatgggc ggtgtgaaaa tcaatacgaa
     7201 cactgaagta ttagataaag aaaaccagcc aattaggggg ttatatgctg ctggtgaagt
     7261 cacaggtggc ttacatggaa acaaccggat cggtggaaat tcagttgcgg agatcattat
     7321 ttttgggcga caagcgggca tacaagcagc tcgatttgct tcggaaaatg aatgaaatag
     7381 aacgtaaata aaaagaggtt gtgaaatcag cgttttgagc taataccgag ggtcagctga
     7441 ttgaacactg tttagtgaag aggttgtgaa aaag
//
LOCUS       DADLIO010000104         7217 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.109, whole genome shotgun sequence.
ACCESSION   DADLIO010000104 DADLIO010000000
VERSION     DADLIO010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7217
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.109"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(229..906)
                     /gene="phoU"
                     /locus_tag="JOX41_002612"
     CDS             complement(229..906)
                     /gene="phoU"
                     /locus_tag="JOX41_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HAY6450303.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            complement(919..1677)
                     /locus_tag="JOX41_002613"
     CDS             complement(919..1677)
                     /locus_tag="JOX41_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HAY6450304.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            complement(1693..2499)
                     /gene="pstB"
                     /locus_tag="JOX41_002614"
     CDS             complement(1693..2499)
                     /gene="pstB"
                     /locus_tag="JOX41_002614"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HAY6450305.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDIHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            complement(2514..3398)
                     /gene="pstA"
                     /locus_tag="JOX41_002615"
     CDS             complement(2514..3398)
                     /gene="pstA"
                     /locus_tag="JOX41_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HAY6450306.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVMKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            complement(3398..4318)
                     /gene="pstC"
                     /locus_tag="JOX41_002616"
     CDS             complement(3398..4318)
                     /gene="pstC"
                     /locus_tag="JOX41_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HAY6450307.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            complement(4433..5290)
                     /locus_tag="JOX41_002617"
     CDS             complement(4433..5290)
                     /locus_tag="JOX41_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HAY6450308.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            complement(5627..7075)
                     /gene="cls"
                     /locus_tag="JOX41_002618"
     CDS             complement(5627..7075)
                     /gene="cls"
                     /locus_tag="JOX41_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAY6450309.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHTTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
BASE COUNT         2093 a         1589 c         1255 g         2280 t
ORIGIN      
        1 ttgcattctt tatcctttct atgaaatgat gaaaagggtt tgtgacatgt tttgtcacaa
       61 accctttccc gaataaacgg tgttcaaaag cttgcatctg cggtaataag tccagccaaa
      121 cgaaaaatat gaggagctat tttttgtttg actgttctta ttacttgatg tagaacagct
      181 ttttcacaac ctcttttcat aaacaaacgg cataatcaca gcttcagttt agaaaatctc
      241 attgtggttc gtatttaact cagtgatttt ccctgtagcc aagtagacga tccattcaca
      301 gatgtttgtc acatagtctc cgatccgttc tagataactg gcaacattca agtagtctgt
      361 tccactgatg actgtctcag gattttcctg catatttttg attgttgcat tatagattcg
      421 attgaaatag tcattgactc tttgatccat attggcgatc gtacgtgcgt ctttttcgtc
      481 tgttttgaca taagcaacta ggacgttgtc caccattttt ttcacataat cggacatatc
      541 ggagatctct ttttcgattt ccggtattct cgtctgccct tttacgcgaa tcgtggattt
      601 agcaacagac accgcatgat cggccatacg ttctaaatcc gagctagctt tcatgaccgt
      661 aatgatcata cgcaaatcag ttgtaactgg ctgttgcaat gcgatcattt caaaactttt
      721 cttctccaag cgtgtttcca tgttattgat atttatatcg ttttcgataa cttcttgggc
      781 taagatttta tcgtgtttga tgtatgcacg aactgacttg tgcacggcgc tgctcaccat
      841 catccccatt tcgtagaact gattatggag attcagcaat tcttcttcaa attgtgtacg
      901 tagcattccg tttcctcctt atccaaatcg acctgaaata taatcttctg tctcttgttt
      961 ttctggattc atgaatatct tcttcgtatc gttgtattcg atcaagtgac catctaaaaa
     1021 gaatgccgtc ttatctgaaa tacgtgaagc ttgagacata ttatgggtca cgatgatcat
     1081 cgtataccgc tctcttaatt ctaacagcat actttcgatt ttcccagtag aaacaggatc
     1141 aagcgcactt gttggttcat ccaataagat gatttccgga ttaactgcca aaacacgtgc
     1201 gatacataca cgctgctgct gcccgccgga taaagataaa gcacttttat gcaatttgtc
     1261 tttcacatca tcccaaacag acgctgcctt caggctttct tcaactactt gatcaaggac
     1321 ttttttatct ttttcccctt ttaatttcaa tccatagatg acattttcat agatagaaaa
     1381 aggaaatggg tttggctgct ggaataccat gccgatttct tttcttagtt caacaacatc
     1441 tgtttttgga ccatagatgt ctttgtcttt atataaaaca cttccggtga tcgttacatt
     1501 cggaatcagg tcattcatcc ggttcaaaga acgcagataa gtggattttc cgcaaccaga
     1561 aggaccgatc atcgcagtga tttccccttg attgaaactt agatcgatcc cttttagtgc
     1621 ttctttcttt ccataataca gatgaagatc tttagatgaa ataatttctt ttgtcatgtt
     1681 gaggcctccg tcttaaccaa aatgaccgga cacataatct tcggttgcct gaatttttgg
     1741 tctggtaaat atcttgttag ttttgtcata ttccattact tttcctagat agaaaaaggc
     1801 agtatagtcg ctgatacgag ctgcttgttg catgttatgc gtcacgatga tgatcgtata
     1861 gtcttctttc aagtttacaa gtgtttcttc aaccgttcct gtcgaaatag ggtccaaagc
     1921 acttgccggc tcgtctagca gcaagatatc aggtttcatc gcgatcgcac gagcaatgca
     1981 taaacgttgc tgttgcccgc cagataaagc caaggcactt ttgtccaagc tgtcttttac
     2041 ttggtcccac aaggcagctt gtttcaagct tgtttcaacg atttcatcta atttcttttt
     2101 gtttttttcg ccgtgctgtt tcaaagcaaa tgtaatattg tcataaatcg acttgctgaa
     2161 cggattagga cgttgaaaaa ccatgccaat ccgtttgcgc atctcataaa catccacttg
     2221 aggcgcatta atatctacgc cttgatacat gattttccca gtgattttcg tattagcgat
     2281 cccatcattc attcgattca acgaacgaag atacgtagat tttccgcagc cggaaggacc
     2341 aatcagtgca gtgatcttat ttttttcaaa ttccagatcc actcctttga ttgcttcatt
     2401 gtcgccatac cagacatgta tatcatccgt atatagtgct acttctttct cttttggcat
     2461 ggtgatgaca tttgtttcat tccagttata ttttttcatt ttgcttcttc tccttaggct
     2521 gaagtcattt ttcggtataa tcgtttgcca atcgcacgag cgccgaagtt gaacagtaaa
     2581 acagcaatga tcaacacggc agaagcgcca gccgaaacag aaacaccatc aggcatcgtg
     2641 ccttctgtat tgatcttcca aatatggaca gctaatgttt cagcttgacg gaaaatgctg
     2701 atcgggcttg aaacacttaa tggattccag ttcgtaaaat ctaacgcagg tgcactttgt
     2761 ccagccgtat agatcaatgc agctgcttca ccaaaaattc ttccagaact taggatcaca
     2821 ccagtcaaaa tccctggtgt cgcttctgga accaccactt tcatcactgt ttcccagcgt
     2881 gacaaaccta aggccaatcc tgcttctcgt tgtgtgtaat ggaccgcttg taaagactcc
     2941 tcaactgttc tagtcaaaag aggcaagttg aatacagtca aagccaatgc accagaaata
     3001 atcgagaaac catactggaa ttgaataacg aaaaccaaga aaccgaataa accgacaacg
     3061 acagaaggca acgagctcaa gatttcaatc gacgtgcgaa tcacatctgt tagccagttt
     3121 tttccagcat attctgaaag atagataccc gcacctaaag aaataggaaa actgatgatc
     3181 atcgtgatca aaagcaaata aatcgagtta aatagctgga tcccgattcc accaccttct
     3241 tggtaggctt tggaaggttc ggtcaagaag gaccatgaaa tgtgcggtat tccccgaact
     3301 aagatataaa gtagtaaagc tgctaaaatc aatacgatga tccccgaaac tatatataaa
     3361 acacctgtag caattttatc tgagcgtttt gcgttcatta tttcagctct cctttcttcc
     3421 caatcatacg gatcacgata ttaaagaata atgacatcaa tagcaagatc agcgctaatg
     3481 accataacac attattttca actgttccca tgattgtatt tccgattccc attgttaaga
     3541 tggacgtcaa tgtagaagca ggagtagtaa gtcctgttgg catcaatgct gcattaccga
     3601 tgaccatttg gatagctaag gcttcaccaa acgcacgagc cataccaaaa acgactgctg
     3661 ttaaaatccc gggcacggct gctcgtagca cgactttgta gattgtttgc catcttgtgg
     3721 caccaagcgc taatgaagct tcccgatagt gccgtggtac tgcctttaat gcatcaacag
     3781 tcatcgttgt gacagtcggc aagatcataa cgaacaacac aaatgtacca gctaagatac
     3841 caaaccctgt cccgccaaaa atacttctga caaaaggcac gataactgat aaaccgataa
     3901 aaccataaac gacagaagga atacctacaa gcagctcgat gaccggctgt aagatcttcg
     3961 ttccgttttt aggagagatc tccgtcatga atactgctgc accaatggca aatggcgtgg
     4021 caacgatagc agataaaaag gtcacaataa acgaacctgt gatcataggc aatgccccta
     4081 ccattggttt cccatttgct ccgatttggc ttggattcca atctgtacca aacagaaaat
     4141 caaatacatt gatcttatca gtaaaaaagg tggccaatcc tttactagct acaaaataaa
     4201 aaatagataa tacaaccaac acgatcagcg cgatacataa aaaactgatg aattttccac
     4261 gctgttccat ttttgaacgt tttgattttg ttaataatac ttttttcaca tcttccacag
     4321 atgactcccc cttaatcagg tttaacatac tcactcagtg tacaaattga acatcaattt
     4381 ggttttaata acatgtaaaa gtttagctaa gtttgtaaat tttgtgtaaa gattactctt
     4441 taacgatatt tccttgccaa tcacgttcga ctttcatatg agaaacaggg atataaccta
     4501 gttctccaac gatgttatct tgtacttcat cagataagat atagtctaaa aattcttttg
     4561 tcagtttttt tggatgatct cttgtgtaca tatgctcata tgcccaaatc gtccatttgt
     4621 tcgttgtcac attttcatct gtcggttcta caccgttaac attcaacgta tctacatcat
     4681 cggaaacata agaaaaagca acatagctga ttgcaccggg tgtgtcggca acgatctggc
     4741 gcaccattcc gcttgaatct tgttcttgtg cctgaacagc tgtttctccg tccaataccc
     4801 atttttcaaa cgtgctacgg gttccgcttc ctgaagcgcg gttcaatata actactggct
     4861 gatcttttcc accgacttca ctccagtttt tgatctcgcc tgtaaatagt tttttcaggt
     4921 tttccatact gatgtctttt acgccaatat ccttgttcac aataggagtg atcccaacaa
     4981 ctgctactcg atgatcgact aatgctgagg catcgatccc cgatttttct tccgcaaaca
     5041 aatcagagtt tccgatgtcg actgctcctg actgtacttg agacaaacca gttccgcttc
     5101 cgcccccttg tacattgatg aattttccag gattttctgt ctggtaagtt tcagcaactg
     5161 tttctactaa aggctgtaaa gcagaagagc caacagccgt aatggattct cctcgatcaa
     5221 tccactttga acagcctgat aaaagaatgg ctaatcctat tattggtaag aataatttaa
     5281 gttttttcat tagaaatctc ctttaatcct aaagtatgtt tattttatca ttttcattac
     5341 ttgatgaaaa cgaatcaaaa tcattaaata acaaaataaa ttctcataat tgtaaaaaaa
     5401 actatctcat taaaagtttc tatgctatac tggctttgaa atgtgtctct tttaatagca
     5461 tatattagct tatttcttgc tttccccaaa aaacaagaga taccccaaag ttaatttcgc
     5521 tcatgcgaga cgctttctcc atttctgacg tactctcaga aatggccccg ttagaaaagg
     5581 acacgagatc tccatctgtt gatggttctc atgtcctttt tatgttttaa aggagcggcg
     5641 aaatcaatct tgctaatcct tctttcatct tgatgattat tcctcggttt tcatacattt
     5701 cttttgtgag atgcgtagaa attttcgagt cttcaaaaaa agcttttctt acacgtgaag
     5761 ccattcgttc atcataaacc agtgtattga cctcaaagtc caagcgaaat gaacgaacat
     5821 cgatatttgc tgagccaact gaaacaatgc caccatcgat aatcatcgtc tttgcatgaa
     5881 taaatccatt ctcatatgtt tcgatccttg ctccatactc gatcagctct gcagcgaaag
     5941 aatacgttgc ccagtaaacg agaagatgat ctggtttgtt aggtatttgg atatgaactt
     6001 ttacgcctga aagaagagcc aacttcagtg cttcatgaat cgatccatcc ggtatgtaat
     6061 aaggcgtttg gatcaatatc tcccgtttgg ctaacgaaat cattttcaaa taagtcattt
     6121 tgatttgttc atgttcggta tctggtccgc ttgtcacgat ttgaacagct atatcaccag
     6181 tagtgtgaat ggacgggaaa aatttgggag aatagcctac ttcttttgta tgctgagaat
     6241 tccagtccat caaaaaacgg ttttgcaagg tatacaccgc ttctccgtaa atacgcaaat
     6301 gattgtctcg ccaataacca aatttcttta ccaatcctag atattcattt ccaacattga
     6361 acccacctgt atatccgatt ttcccatcaa taactacgat tttacgatga ttgcgataat
     6421 tgatccgagg attaatatac ggaacaaata gaggaaagaa aaatgcgact tctccgcctg
     6481 cttttttcaa attctgaaaa aagctggaag aaacttgtgt ggaaccccat gcatcaagaa
     6541 ggactctgac ttttacccct cgtcttgccg cctctgtcaa tgcatctcga acttcttcac
     6601 ctaatgcatc actgcgataa atataatact ggaagtggat atggtcttct gcctgcttga
     6661 tatcttcaat cagcgcatcg aatttttcac gaccatctgt aaataaagtg atttcatttt
     6721 tagtcgtata gagcgtactt tcaaataccg tgagcatata gatcaattgt ttcacatcta
     6781 cttgtccagt aggcggatga ggataaagcc ctcgcatcaa tgcctgtttg tcttcttcaa
     6841 tttccaggtt cttaccgatt ttcccttgga tcttcaaatc aaagattttc tctttggaaa
     6901 tccctcttcc taaaaaaata tataaaataa atcctacaac tggaatgaac atcaaaacga
     6961 gcagccatgc ccatgtttga gcagtttcct ttctttctcg aaaaacgatg ataaaggaaa
     7021 gcaaaatatt cataatcaaa aggatcgtaa aaaaattgtc aacgataatt ttcacggctt
     7081 cacctcttct tctaccaact taagaatacc caagttgttt tttaaagtaa agggaaaaaa
     7141 gccgcttcct tctattctcc tagccaataa aaaaagaaag ctggaacgaa actgtccaac
     7201 tttctcattt tatttat
//
LOCUS       DADLIO010000105         6984 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.111, whole genome shotgun sequence.
ACCESSION   DADLIO010000105 DADLIO010000000
VERSION     DADLIO010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6984
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.111"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            296..892
                     /locus_tag="JOX41_002619"
     CDS             296..892
                     /locus_tag="JOX41_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAY6450310.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAEEKEYMNDADRFRVFG"
     gene            complement(950..1432)
                     /locus_tag="JOX41_002620"
     CDS             complement(950..1432)
                     /locus_tag="JOX41_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450311.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(1538..1735)
                     /locus_tag="JOX41_002621"
     CDS             complement(1538..1735)
                     /locus_tag="JOX41_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450312.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            2030..2788
                     /locus_tag="JOX41_002622"
     CDS             2030..2788
                     /locus_tag="JOX41_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HAY6450313.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            2848..3276
                     /locus_tag="JOX41_002623"
     CDS             2848..3276
                     /locus_tag="JOX41_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450314.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            3322..3394
                     /locus_tag="JOX41_002624"
     tRNA            3322..3394
                     /locus_tag="JOX41_002624"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3355..3357,aa:Gln,seq:ctg)
     gene            complement(3544..3915)
                     /locus_tag="JOX41_002625"
     CDS             complement(3544..3915)
                     /locus_tag="JOX41_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAY6450315.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            4130..4315
                     /locus_tag="JOX41_002626"
     CDS             4130..4315
                     /locus_tag="JOX41_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450316.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(4398..4586)
                     /locus_tag="JOX41_002627"
     CDS             complement(4398..4586)
                     /locus_tag="JOX41_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450317.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(4610..4873)
                     /locus_tag="JOX41_002628"
     CDS             complement(4610..4873)
                     /locus_tag="JOX41_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450318.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            5031..5288
                     /locus_tag="JOX41_002629"
     CDS             5031..5288
                     /locus_tag="JOX41_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HAY6450319.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(5359..5550)
                     /locus_tag="JOX41_002630"
     CDS             complement(5359..5550)
                     /locus_tag="JOX41_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450320.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(5691..6011)
                     /locus_tag="JOX41_002631"
     CDS             complement(5691..6011)
                     /locus_tag="JOX41_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450321.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            complement(6034..6468)
                     /locus_tag="JOX41_002632"
     CDS             complement(6034..6468)
                     /locus_tag="JOX41_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAY6450322.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            6803..>6984
                     /locus_tag="JOX41_002633"
     CDS             6803..>6984
                     /locus_tag="JOX41_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAY6450323.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
BASE COUNT         2188 a         1361 c         1069 g         2366 t
ORIGIN      
        1 aattttctat aaaagcaagt aatttttaat ggcaatatca taaaaaaaag aagatagaga
       61 tttaataatt atatatcagc tgtttttttc aaataagcaa aaattcctaa aacacaacaa
      121 tgaaagcgat aactaagaaa atccttacat aacgattttt cttattaaaa ttgttttttg
      181 aacttcgctt attttttgtg agcatatctg tttacttact ttttgtaagg tgctatactt
      241 catttcgtaa tcaattaaaa aaatgcaaaa cgcaaatcaa aggagaaatt ttattatgac
      301 aacttttact gacactttga aaaaccgccg ttcaatctat catctaggac gtaatgtttc
      361 actttctaat gaagaattaa caactttgat caaagaagca attaaagaaa gcccaactgc
      421 tttcaatgct caatcaacac gcgcagttat ccttttcgga gatgcacatg aaaaactttg
      481 ggaaatcact gaagaagcac ttcgcccatt gactccagca gaagctttcc caaatacaca
      541 aaacaaatta gctggtttca aaaatggtta tggtacagta ttattcttca aagatactga
      601 cgtggtaaaa ggtctacaag aacaatttga attatatgca gacaacttcc cagattggtc
      661 agaacaatca aacggaatcg caacagctaa tacttgggta gcattagttg ataaaggatt
      721 gggcgcaaac ttgcaacatt acaacccagt tattgacgaa gcagttgcaa aagaatggaa
      781 tatcccttca aactggaaac tacgttcgca attagtattc ggttcaccag aaacaccggc
      841 tgaggaaaaa gaatacatga acgatgccga tcgcttccgc gtatttggat aattttattt
      901 gaaataaaaa acagaggttg tgacaaacat cttgtcgcaa cctctgtttt tattctggat
      961 caatcataat atcaatctct gcctcatcgt ttaagcgttg ggacaaaaat ggaactaatt
     1021 cttctaatga tgcagaaaat ttcagcatcg gtcctcgcca tccgtttcgg aaaaaattca
     1081 tttttacgat tttagaacct tttggctgat ataatacaat tttattgatc tcagaaaaag
     1141 gaacaccttt tttgtcaaag ctattcaaaa caagtccttc ttctgtgatt cctctactgt
     1201 ccaacaaaaa actaataaaa atcattgctg acaagatccc ttttgccaat tcatctgctg
     1261 taggatgact gatgagtgta taccaaatga ctagtgacac taagaagggt atcaccaagt
     1321 agacccatcg atttcgcaca gtccgataaa taatttcttt tcgaaccagc caaagaaata
     1381 aaaacatcac aacaacgaat aaaaacaata gaaccgtaaa gaatgttacc atgacaactc
     1441 gcctcgcttt ttcttctcca gaaaatagga aaagaatact gatttacctt ctcaaagaaa
     1501 ttggacttgc agcacgccgc acgtccaatt gttttcttta ttcaaatgta tcatattttg
     1561 caacaaccat gcttgctttt tcatctaata attcttggtc ctctgcagca cattgggcaa
     1621 ctttgaccac ggcgcagttt gtcatttttg atacaacttc accaatgacc gtttttgtaa
     1681 aaccaattgg tttgcatgca tattgttctc ctaaattaat catttcttcc gtcatcaaaa
     1741 tcctcctaaa ctgctggaac ttttctccac attaccactg ctatttcttt ggagatttaa
     1801 ctcattgatt tttatttaca gttaaaaatc aaccttacag gcattatagc gtactgtttt
     1861 cgttttcaca attaaaacag ctgttgtatt tagaagaatt tttttcaaaa aattaaaaca
     1921 tattccttaa aaactaatta tttcctacat attaaaatat aatacttcca tttccaataa
     1981 aaatacattt ataataggaa agataaacag ctgaaaaggg agatttcaaa tgaagaaaaa
     2041 aacgttcaaa aaactattgt ttctaggggg cacagctgct cttttattaa gcggtacaag
     2101 ttattaccta catatccatt ctccagaaca tacaatgaac actgcacaaa aaagttcaac
     2161 acaaaaaacg aaaaagacaa aagagaaagc agaagtttta ctagatgttc cattagagag
     2221 ccagtttgat tctccttctt tagaaaatgg ctgtgaagtc acttcgcttt ctatgctttt
     2281 atctttttat ggttatgaaa caactaaaaa ccagttagct gagcaattgg attacgtccc
     2341 tgttttcaat gcagatggga ctcatggcga tcctaatgaa ggatttgttg gtgatatcag
     2401 tggcggagac tgggctatgg tcgtctatgt tcccccagtt gcctcccttg ctcagcaaat
     2461 cgtccaaacg gattatcaca cttttccaaa aaccgatgct caactcgatg atatcaaaaa
     2521 agcactatct aaaggaaatc ctgtctggac ttctgtgact atcaattttg aagtcccaga
     2581 tgaaactgat tttatgactt ggaccacaaa taatggagaa gtaagagtca ctcctcttgt
     2641 tcatgcttgt gtagtcactg gatatgacaa agaaaatatt tatgtcaacg atccctatgg
     2701 tgtaaaaaat cgagcagtac cgatcaacga tttttcggcg attttcactg caatgggtgg
     2761 acagatgcta actttggaga aaagctagta attcaaacaa aaatccctta tactcaagat
     2821 accaaacctt tgaagggagc gtagataatg gaaaaattca cacataaaaa aatggatcca
     2881 aatgaaattc cgattatttt tgtccgtgac tgcaagggaa atgttcaagg taaagtctct
     2941 attaatgagt ggaacgagcg tcgcagacct gctaccctca atgaactgga aatcaaattg
     3001 tatcgtcaat ctcttgttta ttacgcagat caagagtacg agaaagccac cgatttattg
     3061 aaatttctaa ttgctcgaac agagtatact cgctttgaat atattgaacg tttagcaaac
     3121 atctatcata ttatgaatga acctgtcaaa gaatatcagt tattggacac cgtcttgtca
     3181 gtagcagaac tgattgccct tcctgctgga ttagaaaaga aactagtacg ccgcctttta
     3241 cgagtaaagc aacaactatc cgatcaagaa aaataacttg cgttttttta ggaaagtgct
     3301 atgattattt tgttgaataa atgggatgta gccaaactgg taaggcactt gactctgaat
     3361 caagcaattg taggttcgaa ccctgccatc ccaatttgat gtgcttgctg aaaaaatgaa
     3421 ccccctgtaa aagaacaatc tttttgcagg gggattattg tattattttt actacttgta
     3481 tttagtttac ataattaaat tatgaataat aaaatcgggc gtattcttaa tacaaaaact
     3541 gatttaccca ataattgcta atgctttctc cggaactttt tctctaggaa cttcctcata
     3601 cgtttctatg tgtgctcctt tattgctaat tttcaaataa tgattttctt ttaacacaga
     3661 aagaccatta aattcaaccg ttcgttcttt cccattggca tcagcagctt tctgcacata
     3721 ccttgctgta ccatattcat ttacttcctc tggtttttgt gtctttacat agacctctcc
     3781 tttttcaact aatggattta gctgatcaag tataccaggg atttctccat aacttccttc
     3841 agtataatat ttcagtccaa atagcaaaat accactaatc gccgccagtc caatcaaata
     3901 tttaatcact ttcatctttc tacctccttg ttatatattc agtatatggg tcagttaaag
     3961 aaattccatc cgtcccaagt tggagatttt tctcctactt tagaagcgag aatcgagtgt
     4021 ttttttagta aaaatgatcg ttatttgata ttattgacgt gtggataaat cagtttttct
     4081 cgttttgtcc atgtaaaaaa tcatgttgat agcaaaggat gtgttcaaaa tgaatcaaga
     4141 agaattattt caaaaagtca aggaaatgat taagaacggc aatttcgatg gcgcaaaacg
     4201 atttatcgaa gaacataaag aacaattagg accttataaa gagaaagccc aaaatctttt
     4261 aaaagatgta aatatcgaca gtgtcaaaaa caaatttaaa aatctattca aataagtaaa
     4321 actttcactt ttgtaaaatc aaaggaggac aatgctgctg catcgtcctc ctttggttct
     4381 tttctgaata cttcatacta aaataaacgt gtcggatcgt aatgataagt cacattgccg
     4441 ttcagtgagg cttttcccac cacatattta cgattctcca acttcagcca cgcttctcga
     4501 aaagccatta attcttctct ttttacatca atcttttcga tttttccatc gatcaaatct
     4561 tgaataagtt gttcatatgg attcattttt ttcctccatc tgctgtcaat caataagttg
     4621 taaaaatagg ttcatatgct tttttggtat ctagatcttc tctgactttg actgtcgtat
     4681 aaataatttt ttctactggg atactataat aacttccttc accattattg aatcggtgaa
     4741 cgtctttctt tgctaaaata ccatttattt tattcgtcag tacacgttgt tcgacactgt
     4801 tacttacaac atagtaaatc acccgaatat tattgatcaa atgcaaatcg atttctaaca
     4861 ctacatgatc catgaaaatc ccactccttc tttcactttg attatagcaa gtttctcctc
     4921 taatttcaaa atcgatacag attttaccgg ataaatccac aaaactgctt gcgccatttc
     4981 gcacaaagtg ttattttgta tcatggactt tatttatcgg aggcaatagt atgatcgcga
     5041 tcggtcaatt tgttttttat attccttttt ttattatgat aagcattctt ttctattaca
     5101 taaaatggac aaaaaagaag ttttcagttt tactggcctc tttacctgct gtatatttta
     5161 cttatcaaat tttttctttt aggcattggg aaacaacgtc tgtattaata acacacatca
     5221 tcgaattgac gctttcagta atttttctta ttatttggat ctatttttta tataagaatc
     5281 agaattgaat ccctcgcatg tttaaaaaga aaacgattaa agatgcagca aatttctgcc
     5341 gatctttaat cgttttttct attctgttat accaaaaaaa tgtttgaatc ggtgaaggat
     5401 cgttccttgt tttaattcta taaattcttg tgcgatcggg tacttttctt ccaaattttc
     5461 tttgttcttt tcgatcaggc ttttcgcttc ttcatatttt ttatctgcac atagtgcttt
     5521 tacttcctgt aatacttttc ctgcttccat ttgcctcacc ctcttgccat tttattgctt
     5581 taagttttat ttaagttata cgcattattc tagtttcatc ccaaataacc ttttttcatt
     5641 tttactcctc gaactaatca gttttctaaa ggctgattgg ttcgtctttt ttatttttcc
     5701 tccatttcat tctgctcttc tgttaattta tctaatgctt tgattgatgc tgcggctctt
     5761 gcataatcat agctgtataa ttccataaat ttatcaggca gaacaaacca cgctggatga
     5821 taaccgttag ctgtgacagg gaatccttta tcttgttggt tatctccatc ccatctcaga
     5881 gcaacacctt tttttccttt ccactttact aaagcgatcg agtatccctt ctttgtttgt
     5941 gtgccgtctt caataattgc taaaatttct attttttctt ttggcgcacg gacttcttga
     6001 ggacgaacca ttttctattc ctcccttatc tcattacttc acgaccaaca cactgcaagg
     6061 ggcatgtgat acgacataag aagcggtcga tccaactaat gcttgttgta tagcaccttt
     6121 tcctgtcgct cccataacga tcaaatcaat attttcttgt ccagggatga cattggcaat
     6181 caaatttctt ggatctccag tttcaactat tgcgtggatc tcagcaatgc cgtactcttt
     6241 ggcatcattg atttttttca gcatggctac ttctgttctt tgtttttcat ctgcatagat
     6301 ttttgaaaag gcataggcac tatgggtcag ctcaactttg ttgatgattg acacgataaa
     6361 taagtgggct tcattgtcct ttgctaagtc aagggcttca gcgaacgctt tgatcgattg
     6421 tcttgatccg tcaactgcta ccatgatgtt ctggtatctt ttactcattg gaaccgcctc
     6481 ctttttcttt tattgtaaca tctcaagcaa aaatacaaaa aatatacgca atatgtaaat
     6541 aaaatgatga acaaaagcaa tttctttcaa gttatttata catttctttt ctcatcagaa
     6601 cacctgttct aatcccatta tttctgcatt atgtgaaatt cctcatcatt tttcacatcg
     6661 agcgaacatc attctgttac aaaaaacgtg gatttgtcat aaattgtcat gcttctttta
     6721 cctatgaaat attttcacgt gttaaagtat tcctcgttga acacaacaaa taaaactttt
     6781 taacgaataa aggagatttt tcatgacatc acttaaaact ttactttttg gaacaacttt
     6841 ggctgccggc gctgcattct tcatgggaac gactgctcat gcggacgaag cttataccgt
     6901 tcaatcaggt gatactctat caacgatttc tcaaaaatac gttggtgata actccttgat
     6961 caatgccatt gcagaatcaa attc
//
LOCUS       DADLIO010000106         6967 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.112, whole genome shotgun sequence.
ACCESSION   DADLIO010000106 DADLIO010000000
VERSION     DADLIO010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6967
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.112"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(<1..203)
                     /locus_tag="JOX41_002634"
     CDS             complement(<1..203)
                     /locus_tag="JOX41_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HAY6450324.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYVLIDEKVKKR"
     gene            complement(640..900)
                     /locus_tag="JOX41_002635"
     CDS             complement(640..900)
                     /locus_tag="JOX41_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450325.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIESMQIRNPDHFTRSMGI"
     gene            975..1178
                     /locus_tag="JOX41_002636"
     CDS             975..1178
                     /locus_tag="JOX41_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HAY6450326.1"
                     /translation="MIKTVKFVTVAIRLKVRWCVCAYFQNLTERRSLLPVETALGLMI
                     SFGSLIATIIFGILAVVNNNQKK"
     gene            complement(1319..1804)
                     /gene="ssb"
                     /locus_tag="JOX41_002637"
     CDS             complement(1319..1804)
                     /gene="ssb"
                     /locus_tag="JOX41_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAY6450327.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSSSPSPTTFEQRDVATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            complement(1807..2706)
                     /locus_tag="JOX41_002638"
     CDS             complement(1807..2706)
                     /locus_tag="JOX41_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HAY6450328.1"
                     /translation="MTPTQFAAKTRNLAKSTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTEQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIRGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            complement(2719..3312)
                     /locus_tag="JOX41_002639"
     CDS             complement(2719..3312)
                     /locus_tag="JOX41_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection protein"
                     /protein_id="HAY6450329.1"
                     /translation="MQDKLKELLAIRDGNLSMKEARKFGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEFEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            complement(3553..5757)
                     /gene="topB"
                     /locus_tag="JOX41_002640"
     CDS             complement(3553..5757)
                     /gene="topB"
                     /locus_tag="JOX41_002640"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAY6450330.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFSGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQAGADHGKIFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGTIHQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKTVGKVPVDLGWKKLFGK
                     ESDRKEKEEEPLLPKVTKGEAVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGEQKGTQATFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEATRHLGVCPKCREQEVLLYQNVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNGRTSQSVRGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNYKKRTRRTTK"
     gene            complement(5768..6790)
                     /locus_tag="JOX41_002641"
     CDS             complement(5768..6790)
                     /locus_tag="JOX41_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HAY6450331.1"
                     /translation="MIAELKPKHERQNFLVRDDRLDHAVAFLWKDPQTNETVGASYQG
                     TFIDYERFGERGTYKHIDKNSTANHGFNLKIGDPKQLKFFESSIDLLSYAALNRDQLN
                     DTWLVSMEGLKHHVISHYFGEAVSELRKKQAFPQSIEICVDNDRAGHIFYEKEQLMGA
                     VDPFTNQKVRCERGIANDWQVPKEYKVIYEEVAKEEKITPEAIMAIHKTENNLQLTNQ
                     LVSAHKVNASFGQQLSVNDSIEAINLKDICREVAKELKACERVDGTYDFDRFYQEKGD
                     INAQILFSYKAEQYYKGYKNHEHEFVPEVKKDWNDQLKHEIYQQEIRKQKRAMLFQQG
                     RQQERE"
BASE COUNT         1763 a         1425 c         1212 g         2567 t
ORIGIN      
        1 cgtttcttta ctttctcatc aatcaaaaca taatcgccat aagacaaggt atattttttc
       61 ccgcatgttg gacattgata caaacgatag cttttgatac atttcgctct ttctccacaa
      121 tcgcattcga cagtatgtgg tgcatgatag tttgggaata attcgctgaa gggaacaccc
      181 caataatcaa atttctttcg catgattgat tctgcctcct cttaggaaag gttttatttc
      241 ctttcgttag ttctttcttt attgatttgt tggccagaat gaatcaacga aaagcgacaa
      301 ggacaagggc gcgcagcgtg ccatttaccc ttgtccttgt cgctttttgg tgataaaagg
      361 caacttgttg ccggtctggc aaatcaataa agagatagcg aacaggaacg aaccttttgg
      421 tgagaggaag ttttttctat tttgtcttgc tttgcaagac accatatctt agtgaacgtg
      481 caacgttcac ttcctttctt ctcgaacggc ggtggcggtt ggagtgagag aaaagttttt
      541 caattgagaa ggcacttgtg tcttcctaaa aaggtctttt cctgtttcta tgtaaaacaa
      601 aaagagctgc aatcctcatt taggactgca gctcttcttt tatatgccca tcgatcgcgt
      661 aaaatgatcg gggtttctaa tttgcatcga ttcaatgact aattgattcc gtttattgaa
      721 atgacctgtg acggcaatat tgtattttcc atcatccata attaacaatt tatcgataat
      781 ttcaatatct gcaactacac aattaatcga ttcatgaatt gtttgtaaag taaagcgaac
      841 caataatggt tgtgttttta ttactcggat tttatcaagc aaaccaacat atttgttcat
      901 cacgatcacc tcgctaaaat tatagcaaaa acagctaaaa ttgagaattt ttattcgatt
      961 ttagatatgc tataatgatc aagacagtaa agtttgtgac ggtggctatc cgattgaaag
     1021 tgaggtggtg cgtatgtgcg tacttccaaa atcttacaga aaggagaagc cttttgcctg
     1081 ttgaaacggc gctaggatta atgattagtt tcggttcttt gatcgcaaca atcatttttg
     1141 gaatcttagc agttgtaaac aacaatcaaa aaaaataacc gtcagcttta gccggtcgac
     1201 gattattttt caaaaataat attaagctgg tcaccgtctt aaacggtgct gttaggggag
     1261 ttgttagcgc aactcctctt ttcgtatcca ttataacaac tttattgatc ttttacaatc
     1321 agaatggtaa atcatcatca ctaatatcga ttgattgtcc gccaaatgga ttttgtgaag
     1381 cgttcaatcc attgttgtta ggcgtagcta catcccgttg ttcaaaggtg gtagggcttg
     1441 gactgctgga cgattgatca gcgtgcgcac ggctttctgt cgctgcttta ctttctaata
     1501 gttggaaatt atcggccaca acttctgtca catacacacg ttgtccttgt tggttatcgt
     1561 aggttcgggt ttgaatccgt ccaacaacgc cgatcaaact gcccttttta gctaatgtcg
     1621 ccatcgtttc tgctggtttg cgccaaatca cacagttaat aaaatcagct tctcgattgc
     1681 cgttttgatt cgtgaaattt cggttgacag ctagggtaaa agtcgctact gcagtaccac
     1741 tcgcggtata acgtaaatct ggatctttgg ttaagcgtcc tactaaagtt acattattga
     1801 tcatctttat ctctccattt cttgattcat ttgttgtgat cttttaaact gccgttttct
     1861 ttcttgattt tcaattttga tcacactttt cattaggtga tcaatttcgt tgactgtatc
     1921 tgtaaatgaa atggaattcg caaacgtgtt aactgagcga tatttttccc actgcttttc
     1981 caaatagtca tttcctctga tcttatccat ttctctttca taataaaagg acaacggttt
     2041 tgtatcccca cgttttgtaa atgtatttcg aacacttttg tataactctt tcgtatcgat
     2101 attttctagt ttcggaatgg taaataagtc gtagtaatct tttgctctcg aattatctgt
     2161 gccaaagctg aacgtagcac ttagcttttc tgcaataatt tgttctgttg gataagctgg
     2221 aatctccact tttttatctt caaacattaa ttggtgatag tgtgtatcta cttcaggata
     2281 aatagaatct cctgttgtca cgtccatttt aaacggtaca cgtactttct ctaaattagc
     2341 caccaattta atttgaaatc caggataaaa atcggcttct cttgtttcct tcattccttg
     2401 aatagagaaa acaatgcctt cttttgtggg ttttctagtt aaatcattaa aaatgctctt
     2461 caatttttct tcagttaatt tgctatttct aaatgtcgta tcgatatcaa ttgttgtcct
     2521 tctatcgatt ccatattttg atcctaataa aaagccgcct ttcaaaatga agtcattttt
     2581 gtactttgat tcagaaattt gttcaattag acgatccatc ataaaatgcc gttgcactaa
     2641 ctgtgcattt aatcctgtac tctttgctaa atttcttgtt tttgctgcaa attgtgtcgg
     2701 tgtcatcttt ttcctccatc aatataagct ttgcatgtgg tatttcattt ctttttctac
     2761 atgtagtttt gtcatgtaat ctcttaattt acttggatct ctcaatgggt cttccatgta
     2821 ctcttttaat gcttctaatt tcatttcata ttcaaattca tatctcggat tccaaatatc
     2881 acaaagtgta cgctctttat catacatagt aataggattt ccttgaaagg aagttccctc
     2941 tacttttcct agttcataaa cttctttctt cacgaaatga aattgtaact gctgctcttt
     3001 tgtaattgaa cgatcaacgt tatagccatg gggaaaagtt aagtgaatga atttcggcat
     3061 attcgtagaa agctggtaaa tatctaaagt cgtttcatga gagaagattc ccctggaaaa
     3121 tcgttgctga agccaaaata aatcatctat tccatgacca tcctctacat aataaccacg
     3181 atcaactttg atcaattttc cttgattcac caatctttgt acagtggttg ctgcgattcc
     3241 aaatttcctg gcttccttca tagataaatt tccatcgcga atagccaaca attctttcag
     3301 tttatcttgc atttacttcc cctcccttcg ttacaaatac actacatcaa atatatcata
     3361 gtagtttatt tgtaacaaga ttaacgtcta tcgatctaat tcgatttctt tttgaatgcg
     3421 ctgctggttc tttaattgtt gcagtcttct tttatttgca cgtaatttct cttgttctaa
     3481 acgaattttt gctttttgat tttcgatttc ttgttgtttg tgtgttgtat ttcgcatagg
     3541 ataacccctt cattattttg tagtgcggcg tgttcttttc ttatagttcg tttttttctt
     3601 ttcagaaaat tcaaagcctg ttgtaaagtc ttcttttaaa acgatcgttg cttcaaacga
     3661 acctttctga ccttttagtc ctctgactga ttggcttgtt cggccgtttt gaatgatctc
     3721 tttcagttgt gtggctgtga gtttcttttt ggcaatcgtt gtccataatt taaaatcaca
     3781 ggcttcagac gtacatgccg ccacattttg ataaagcaag acttcttgtt cccgacattt
     3841 tggacaaaca cctaaatgac gcgttgcttc ctgtttttca ctggctgctt tcacctcttg
     3901 taacgttgat ccaaaatctg ttgactggat ttgtcccggt acgacttcca acaagtgaga
     3961 gacaaatttt tggatattag ctaagaaagt agcttgtgtt cctttctgct caccaatctt
     4021 taataagtaa ctttcccatt tggcggtcat ttcggcactt gttagcagcg gctctttttc
     4081 cacggcttgg caaagtaaaa tccctttatt tgtcaccaca agcttatttt tttctacctt
     4141 gatatattcc ttttgtttca aagtttcaat aatatttgct cgtgttgctt ctgtaccgat
     4201 tccttctact tctttcaata tggattgtgc ttcttcgcta tccacggttt ttccagctgt
     4261 tttcatcgct gtgatcaacg taccttcggt ataaggttgt ggtggcttcg tttctttttc
     4321 aaggacttgt agatctaccg tcaccgcttc tccttttgtc actttaggaa gtagcggttc
     4381 ttcttccttt tcttttctgt cgctctcttt gccaaacagc tttttccaac ctagatctac
     4441 tggtactttt ccgactgtct ttagctgaag ctgctgaact tgcgtcaaga tcgttgtttc
     4501 ttcataggta tacttttccg caaacatggc caccgttgtt tttaacactt gttcataaat
     4561 agcctgctgc agtggactta attgttcaaa agccgctgcc gtcatgaccg tctttgtagg
     4621 aatgatcgcg taatgttcct ggactttctt attattcaca tatcgactat tcggtgtatg
     4681 aataggagta ggaatggctt cggcctttaa aaagtgtttg tattcgtcta agtgatccaa
     4741 cagatacgca tactcccctt ctgtaatata aggggtatct gttcgtgggt agcttagata
     4801 tttcccttca tacaaccctt gcatggcttc caaagtatct ttggcactag ctttcatgag
     4861 ctgattcatt ttagattgaa ggctggatag agaaaaaaga cgtggacttg ccgcactttt
     4921 tttctcggtt tcaacttggt ggatcgtacc tggctgtttt cccaattgaa cccccttttc
     4981 ttttaaataa tcttcaaatg cttcttgcgt cgcttgggtt tcattcggat caagcttcgc
     5041 atcaaatgcg ccattttgag cgattacttg ggcttttcct tcaaaatatg gttctttttg
     5101 gaagtttcta atcttttcct gtaattgata aatcatgtaa agcgttgggg tttggactct
     5161 gcctaaggaa aaacttcctg gtatgccttt ttgctgcaag agtaaactat acagcgggct
     5221 accgttcatg ccgatcaacc aatcggcgat ctggcgtgct tgtgcttctt caaattttgg
     5281 gtaggtctct tctgcatctc gtaactgctg gaatccctga taaatggctt ctttttctaa
     5341 ggagttgatc caaagtcttt taaatatctt tccatgatcg gcgcctgctt gttgaatgat
     5401 cgtccaagct atcagttccc cttcacgatc gctatctgtc gcaataataa tggtgtcggc
     5461 cgattgaagt tgctgtttca ccaccttgaa ttgctttttc ttatctttag gaacatgata
     5521 gtgataatgt gtagggaaaa taggcaaatg ctctaatgac cattgtttcc aattttcatc
     5581 gtacatatcg ggcgaatcta actcgactaa atgaccaaaa ccatacgtga tcacagtttc
     5641 tcctgaaaac aatcgatctt ggatctcaaa atacccatct tttcgggtag ctttagaaaa
     5701 gctatcggca taagccttcg cttgtgacgg tttttctgct aaaataacgg ttttcatcat
     5761 gacgatttca ctccctttct tgctgtctac cttgttgaaa caacatggca cgtttttgct
     5821 ttctgatctc ttgttggtag atttcatgct tcaattgatc attccaatcc ttttttactt
     5881 caggtacaaa ttcatgttca tgatttttat agcctttgta gtattgttct gctttataag
     5941 agaaaagaat ctgagcatta atatcccctt tttcttgata aaaacgatca aaatcgtacg
     6001 taccatccac gcgttcacaa gcttttaatt cttttgcgac ttctctacaa atatctttca
     6061 aattaatagc ttctattgaa tcgttaacag aaagctgctg accaaaagac gcatttactt
     6121 tgtgagcgga aaccaattgg ttcgttaatt gcagattgtt ttctgtcttg tgtatggcca
     6181 taatagcttc tggtgtgatc ttttcttctt ttgcgacttc ttcataaatg actttgtatt
     6241 cttttggcac ttgccaatca ttagcgattc ctcgttcaca acgtactttc tgattcgtaa
     6301 atggatcaac tgcgcccatt aattgttctt tttcgtagaa aatatgtcct gcacggtcat
     6361 tatccacaca aatctcgatg gattgaggaa aggcttgttt ctttctcaat tcagatactg
     6421 cctcaccaaa ataatgactg atcacatggt gttttaaccc ttccatcgaa actaaccacg
     6481 tatcgtttaa ctgatcacga tttagtgcag catagctaag taaatcaata ctactctcaa
     6541 aaaattttaa ctgcttaggg tcaccgatct ttaggttaaa gccatgattc gctgtcgaat
     6601 ttttatctat atgcttatat gtgcctctct caccaaaacg ttcataatca atgaacgttc
     6661 cttgataact cgcccctact gtctcatttg tctgtggatc tttccataaa aaggcgaccg
     6721 catgatctaa acgatcgtct cgaactaaga aattttgccg ttcatgtttt ggctttagtt
     6781 cggcaatcaa cccttctttt tctgcataat caatcagcca ctctggtagt tttcgttctt
     6841 ccttcagata attccttcct ttttctgtga gtggttgata atcaacgggg tgatctttgt
     6901 acttttctgt ctcaaaatga agattttcta ctcgttctgt tttgtcttca ttctttagaa
     6961 taaaatc
//
LOCUS       DADLIO010000107         6919 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.113, whole genome shotgun sequence.
ACCESSION   DADLIO010000107 DADLIO010000000
VERSION     DADLIO010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6919
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.113"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            178..1200
                     /locus_tag="JOX41_002642"
     CDS             178..1200
                     /locus_tag="JOX41_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HAY6450332.1"
                     /translation="MIAELKPKYERQNFLVRDDRLDHAVAFLWKDPQTKETVGASYQG
                     TFIDYERFGERGTYKHIDKNSTANHGFNLKIGDPKQLKFFESSIDLLSYAALNRDQLN
                     DTWLVSMEGLKHHVISHYFGEAVSELRKKQAFPQSIEICVDNDRAGHIFYEKEQLMGA
                     VDPFTNQKVRCERGIANDWQVPKEYKIIYEEVAKEEKVTPEAIMAIHKTENNLQLTNQ
                     LVSAHKVNAFFGQQLSVNDSIEAINLKDICREVAKELKVCERVDGTYDFDRFYQEKGD
                     INAQILFSYKAEQYYKGYKNHEHEFIPEVKKDWNDQLKHEIQQQEIRKQKRAMLFQQG
                     RQQERE"
     gene            1211..3415
                     /gene="topB"
                     /locus_tag="JOX41_002643"
     CDS             1211..3415
                     /gene="topB"
                     /locus_tag="JOX41_002643"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAY6450333.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFTGETVIT
                     YGFGHLVELDSPDMYDEKWKQWALEHLPIFPNQYHYHVPKDKKKQFSVVKRQLQSADT
                     IVIATDSDREGELIAWSIIQQAGANQGKTFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEVQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEAYLKEKGVQLGKQPGTILQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIEKVPLDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            3654..4247
                     /locus_tag="JOX41_002644"
     CDS             3654..4247
                     /locus_tag="JOX41_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HAY6450334.1"
                     /translation="MKDKIQCIFDKHNGNLSLKDARSEGLSPMTLDRLAEKDKIEKVA
                     PGFYTLKDAFVDELYLAQSIYSRGIFSHETALDLFQVGTYIPKKINMMFPKGYNVSKE
                     KLDQYAIQPHYTNKENFDLGVTETESFYGNKILVYDLERTLCDMWNPRYKASVEVKQE
                     ALKEYMTSTSRNTNKLRRYMDILKSPKEMTLYMLPLY"
     gene            4263..5162
                     /locus_tag="JOX41_002645"
     CDS             4263..5162
                     /locus_tag="JOX41_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HAY6450335.1"
                     /translation="MTPTQFKEKTRNFAAEKHLNPQIVQRYYMMEKLLECIVESPYHD
                     DFVLKGGFLIGSKYGLENRSTVDIDTTYRNSKLTKEKLETVFSELTANPTKDGIRFEL
                     KGLTETREADYYPGFQAKFIAYLENARVPFKLDITSGDSIIPAALMYEHKLMFEDKTI
                     HIPAYPTEQILAEKLHATFSFGKDNSRMKDFYDLYMIPKLERIDEKNLYKSVQGTFKE
                     RNNQSVFKHLYDQEMPQLVKDEGLREKWKRYQQENYFAKDISFESTLTSVDSLMQSIV
                     EQEKAERKQNFKRSQQMNQEMER"
     gene            5165..5650
                     /gene="ssb"
                     /locus_tag="JOX41_002646"
     CDS             5165..5650
                     /gene="ssb"
                     /locus_tag="JOX41_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAY6450336.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFSLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRMHADQSSSSPSPTTFEQRDTATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            6016..6276
                     /locus_tag="JOX41_002647"
     CDS             6016..6276
                     /locus_tag="JOX41_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450337.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            6717..>6919
                     /locus_tag="JOX41_002648"
     CDS             6717..>6919
                     /locus_tag="JOX41_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HAY6450338.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
BASE COUNT         2513 a         1207 c         1431 g         1768 t
ORIGIN      
        1 gattttattc taaagaatga agacaaaaca gaacgagtgg aaaatcttca ttttgaaaca
       61 gaaaagtaca aagatcaccc cgttgattat caaccactca cagaaaaagg aaggaattat
      121 ctgaaggaag aacgaaaact accagagtgg ctgattgatt atgcagaaaa agaagggttg
      181 attgccgaac taaagccaaa atatgaacgg caaaatttct tagttcgaga cgatcgttta
      241 gatcatgcgg tcgccttttt atggaaagat ccacagacaa aagagacagt aggggcgagt
      301 tatcaaggaa cgttcattga ttatgaacgt tttggtgaga gaggcacata taagcatata
      361 gataaaaatt cgacagcgaa tcatggcttt aacctaaaga tcggtgaccc taagcagtta
      421 aaattttttg agagtagtat tgatttactt agctatgctg cactgaatcg tgatcagtta
      481 aacgatacgt ggttagtctc tatggaaggg ttaaaacacc atgtgatcag tcattatttt
      541 ggtgaggcag tatctgaatt gagaaagaaa caagcctttc ctcaatccat cgagatttgt
      601 gtggataatg accgtgcagg acatattttc tacgaaaaag aacaattaat gggcgcagtc
      661 gatccattta cgaatcagaa agtacgttgt gaacgaggaa tcgctaatga ttggcaagtg
      721 ccaaaagaat acaaaatcat ttatgaagaa gtcgcaaaag aagaaaaggt cacaccagaa
      781 gctattatgg ccatacacaa gacagaaaac aatctgcaat taacgaacca actggtttcc
      841 gctcacaaag taaatgcgtt ttttggccag cagctttctg ttaacgattc aatagaagcc
      901 attaatttga aagatatttg tagagaagtc gcaaaagaat taaaagtttg tgaacgcgtg
      961 gatggtacgt acgattttga tcgtttttat caagaaaaag gggatattaa tgcgcagatt
     1021 cttttctctt ataaagcaga acaatactac aaaggctata aaaatcatga acatgaattt
     1081 atacctgaag taaaaaagga ctggaacgat caattgaagc atgagatcca gcaacaagaa
     1141 atcagaaagc aaaaacgtgc catgttgttt caacaaggca gacaacaaga aagggagtga
     1201 aatcgtcatg atgaaaaccg ttattttagc agaaaagccg tcacaagcga aagcttatgc
     1261 cgatagcttt tctaaagcta cccgaaaaga tgggtatttt gagatccaag atcgattgtt
     1321 tacaggagaa actgtgatca cgtatggttt tggtcattta gtcgagttag attcgcccga
     1381 tatgtacgat gaaaaatgga aacaatgggc attagaacat ttgcctattt tccccaatca
     1441 ataccactat catgttccta aagataagaa aaagcagttt agtgtcgtca aacgacagct
     1501 gcagtcagct gatacgattg tgatcgcgac tgatagcgat cgtgaagggg agctgattgc
     1561 ctggtcaatc attcaacaag caggcgccaa tcaaggaaaa acctttaaaa gactttggat
     1621 caactcctta gaaaaagaag ccatttatca gggattccaa cagttacgag acgcagaaga
     1681 gacctatcca aaatttgaag aagtacaagc acgtcagatc gccgattggt taattgggat
     1741 gaacggtagc ccactgtata gtttactctt gcagcaaaaa ggcataccag gaagtttttc
     1801 tttaggtaga gtccaaaccc caacactcta tatgatttat caattgcagg aaaagattag
     1861 aaacttccaa aaagaaccat attttgaagg aaaagcccaa gtaatcgctc aaaatggcgc
     1921 atttgatgcg aagcttgatc caaatgaaac ccaagcgaca caagaagcat ttgaagccta
     1981 tttaaaagaa aaaggtgttc aattaggaaa acagccaggt acgatccttc aagtcgaaac
     2041 agagaaaaaa agtgcggcta gcccacgtct tttttcttta tcgagccttc agtctaaaat
     2101 gaatcaactc atgaaagcta gtgccaaaga tactttggaa gccatgcaag ggttgtatga
     2161 aggaaaatat ctaagctatc cgcgaacgga taccccttat attacggaag gggaatatgc
     2221 gtatctgttg gatcacttag acgaatacaa gcatttttta aaagccgaag cgattccgac
     2281 tcctattcat acaccgaata gtcggtatgt gaataataag aaagtccagg aacattacgc
     2341 gatcattcct acaaaaacgg ttatgacagc agcggctttt gaacaactaa gtccactgca
     2401 gcaggctatt tatgaacaag tgttaaaaac aacggtggcc atgtttgcgg aaaagtatac
     2461 ctatgaagaa acaacgatct tgacgcaagt tcagcagctt cagttaaagg caatcgaaaa
     2521 ggtgccgcta gatctaggtt ggaagaagtt atttggaaaa gagagcgacg gaaaagagaa
     2581 ggaagaagag ccgctacttc ctaaagtgac aaaaggagaa atggtgacgg tggatctaca
     2641 agttcttgaa aaagaaacca agccaccaca gccttatacc gaaggtacgt tgatcacggc
     2701 gatgaaaaca gctgggaaaa ccgttgatag tgaagaagcg caatccatat tgaaagaagt
     2761 ggaaggaatc ggtacagaag cgacacgggc gaatattatt gaaaccttga aacaaaagga
     2821 atatatcaag gtagagaaaa ataagctcgt ggtgacgaat aaagggattt tgctttgcca
     2881 agccgtggaa aaagagccgc tgcttacgag tgccgaaatg accgccaaat gggaaagcta
     2941 cttgttaaag atcggtgaac gaaaaggaac acaaaccact tttctagcca atatccaaaa
     3001 atttgtctct cacttattgg aagtcgtacc agggcaaatc caatccactg attttggatc
     3061 gacgttacaa gaagtgaaag cagccagtga aaagcaagaa gccgcgcgtc atttaggaat
     3121 ttgtccaaaa tgccaggaac aagaagtctt actctatcaa aaggtggcag catgtacgtc
     3181 tgaagcctgt gatttcaaac tatggacaac gattgccaaa aagaaactta cagcgacaca
     3241 gctgaaagag atcattcaaa atagccgaac aagccaacca gtgaaagggt taaaaggtca
     3301 gaagggttcg tttgaagcaa cgattgtttt aaaagaagac ttcactacag gctttgaatt
     3361 ttctgaaaag aaaaaaacga acttcaagaa aagaacacga cgcactacaa aataatggag
     3421 ggttaatctt atgcgtaata caacacacaa acaacaagaa atcgaaaatc aaaaagccaa
     3481 aattcgttca gaacaggaaa aaatgcgtgc cagcaaacga agactgcagc aattgaagaa
     3541 ccagcagcgg attcaaaaag aaatcgaatt agatcgataa attcctttct tgttaatata
     3601 aaactaacat gttatagttg tgttagtttt atattaactt taggggaaga gtaatgaaag
     3661 acaaaatcca atgtattttt gataaacata atggcaacct atccttgaag gatgctagaa
     3721 gtgaaggatt atcgcctatg acgttagatc gattagccga aaaggataaa atagaaaagg
     3781 tagcaccagg tttctatacc ttaaaggatg cgttcgtgga tgaattgtat ctcgctcaga
     3841 gtatctattc cagagggatt ttttctcatg agactgcgct cgatcttttt caagtaggaa
     3901 catatatccc taaaaagatc aatatgatgt ttcctaaagg atacaatgta tcaaaggaga
     3961 aattagatca gtatgccatt caaccgcatt acactaataa agaaaatttt gacctgggag
     4021 tcacagaaac agaaagcttt tacggcaata aaattttagt ctatgattta gagcgaacgt
     4081 tatgtgacat gtggaatcca agatacaaag caagcgtaga ggtaaaacaa gaagcattaa
     4141 aagaatatat gacaagtacc agtagaaata caaataagct aagaagatac atggatattt
     4201 taaaatcacc aaaagaaatg actttgtata tgttgccact ttattgagag gagtaaagat
     4261 gaatgacacc gacacaattt aaagagaaaa caagaaattt cgcagcagag aaacatttaa
     4321 acccacaaat tgtccaaaga tattatatga tggaaaaatt attagaatgt attgttgaat
     4381 cgccttatca tgatgatttt gtattaaaag ggggatttct gattggatca aaatacgggt
     4441 tagaaaaccg ttcaaccgtt gatattgata cgacttatcg aaattcgaaa ctaacaaaag
     4501 aaaagttaga aactgttttt tctgaattaa cagctaatcc tacaaaagat ggaattcgtt
     4561 ttgaattaaa gggattaaca gagacgaggg aagccgatta ttatccaggt tttcaagcaa
     4621 agtttattgc ttatcttgaa aatgcacgtg taccttttaa attagatatt acttcaggtg
     4681 attctattat tccagcagca ttgatgtatg aacacaaatt aatgtttgaa gataaaacga
     4741 ttcatattcc agcttatcct acggaacaaa ttctagctga aaaattacat gccacgttta
     4801 gttttggaaa agataattcg cgcatgaaag atttttatga cctgtatatg attccgaaat
     4861 tagaacgtat cgatgagaaa aatttgtata agagtgttca aggaacattc aaggaaagaa
     4921 ataatcaatc ggtgtttaag catttgtatg atcaggaaat gcctcaattg gtgaaagatg
     4981 agggcttgag agaaaagtgg aaaagatacc aacaagaaaa ctattttgcc aaagacattt
     5041 ctttcgaatc tacactaact tccgttgatt ccctgatgca atcaattgta gagcaagaga
     5101 aggcagaacg aaaacaaaat tttaagagat cacaacaaat gaatcaagaa atggagagat
     5161 aaagatgatc aataatgtaa ctttagtagg gcgattaact aaagatccag atttacgtta
     5221 taccgcaagt ggcacagcag tggcgacttt ttccctagcc gttaatcgta atttcacgaa
     5281 tcaaaacggc aatcgagaag ctgattttat caattgcgtg atttggcgca aaccagcaga
     5341 aacgatggcg acattagcta aaaaaggcag cttgatcggc gttgtcggac gaattcaaac
     5401 acggacttat gacaaccagc aaggacaacg tgtgtatgtg acagaagttg tggccgataa
     5461 cttccaacta ttagaaagta aagcagcgac agaaagccgt atgcacgctg atcaatcgtc
     5521 cagcagtcca agccctacca cctttgaaca acgggataca gcgacgccta acaacaatgg
     5581 attgaacgct tcacagaatc catttggtgg acaatcaatc gatattagcg atgatgatct
     5641 accgttctaa gtagcatttt ctattggttg catttgctac ggtttatgtt ataatttaga
     5701 caacaaaaag aattttcaat ctataaccaa aaaccactag ctggcgggct agtggctttc
     5761 ttttacgttt ctattataag aattaacggg taggcttact gtctttcttg gcaaatttac
     5821 aatcaagcca tttgcagata tagtgcgcgg ctacttctgc catgattgca aaaacaaaat
     5881 caaaaagaat tttcaaacct ataacctcct ccccttgcca gattaggccg gggtagcaga
     5941 cagcaagact attatagcat aattgaaata tccaaatgat tggatttttg ctataatttt
     6001 agcgaggtga ttgtgatgaa caaatatgtt ggtttgcttg ataaaatccg agtaataaaa
     6061 acgcaaccgt tattggttcg ctttacttta caaacgattc atgaatcgat taattgtgta
     6121 gttgcagata ttgaaattat cgataaattg ctaattatgg atgatggaaa atacaatatt
     6181 gccgtcacag gtcacttcaa taaacgaaat cagctagtta ttgctagcat gtatgttaga
     6241 aatcccgatc attttacgcg atcgatgggc atataaataa aagaagagtt gtagtcctaa
     6301 atgaggattg cagctctttt tgttttacat agaaacagga aaagaccttt ttaggaagac
     6361 acaagtgcct tctcaattga aaaacctttc tctcactcca accgccaccg ccgttcgaga
     6421 agaaaggaag tgaacgctgc acgttcacta agatatggtg tcttgcaaag caagacaaaa
     6481 tagacaaaac ttcctctcac caaaaggttc gttcctgttc gttatctctt tattgatttg
     6541 ccagaccggc aacaagttgc cttttatcac caaaaagcga caaggacaag ggtaaatggc
     6601 acgctgcgcg cccttgtcct tgtcgctttt cgttgattta ttctggccaa caaatcaata
     6661 aagaaagaac taacgaaagg aagtaaaacc tttcctaaga ggaggcagaa tcaaacatgc
     6721 gaaagaaatt tgattattgg ggtgttccct tcagcgaatt attcccaaac tatcatgcac
     6781 cacatactgt tgaatgcgat tgtggagaaa gagcgaaatg tatcaaaagc tatcgtttgt
     6841 atcaatgtcc aacatgcggg aaaaaatata ccttgtctta tggcgattac attttgattg
     6901 atgagaaagg aaagaaacg
//
LOCUS       DADLIO010000108         6644 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.114, whole genome shotgun sequence.
ACCESSION   DADLIO010000108 DADLIO010000000
VERSION     DADLIO010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6644
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.114"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(1..859)
                     /locus_tag="JOX41_002649"
                     /pseudo
     CDS             complement(1..859)
                     /locus_tag="JOX41_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            1102..1557
                     /gene="tnpA"
                     /locus_tag="JOX41_002650"
     CDS             1102..1557
                     /gene="tnpA"
                     /locus_tag="JOX41_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HAY6450339.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1822..1920
                     /locus_tag="JOX41_002651"
                     /pseudo
     CDS             1822..1920
                     /locus_tag="JOX41_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2143..2373)
                     /locus_tag="JOX41_002652"
     CDS             complement(2143..2373)
                     /locus_tag="JOX41_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HAY6450340.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(2603..3421)
                     /locus_tag="JOX41_002653"
     CDS             complement(2603..3421)
                     /locus_tag="JOX41_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAY6450341.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            3582..4271
                     /locus_tag="JOX41_002654"
     CDS             3582..4271
                     /locus_tag="JOX41_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HAY6450342.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4285..5787
                     /locus_tag="JOX41_002655"
     CDS             4285..5787
                     /locus_tag="JOX41_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010759843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAY6450343.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            5800..6276
                     /locus_tag="JOX41_002656"
     CDS             5800..6276
                     /locus_tag="JOX41_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAY6450344.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(6373..6483)
                     /locus_tag="JOX41_002657"
                     /pseudo
     CDS             complement(6373..6483)
                     /locus_tag="JOX41_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2174 a         1032 c         1203 g         2235 t
ORIGIN      
        1 acttgtcctc gataagaatt gtagcgccgt gatttacgtg tgtatgtcgt tacttttatt
       61 cctagcttct tgatcaggcg ctgaactttc tttttattga tagagaaacc gcggtttctt
      121 agttcattgg tcatccgtaa acagccataa tccttgtgct tctcccgaac tttaagcatt
      181 tccgcttcaa tctcttgatc tggattttta cggtccaatc gtttttgcca gtacataaag
      241 attgccttag ggaactttaa agtttctaga agctcaacta atttaaacgg tcctcggagg
      301 cttgcgatga ttcgtgcgat tgcttcattc gtcgttgttg ggcttcctgt tttcgcagct
      361 tcctcaattc ttttaaaaag gcattttcaa tttgaaggga acggactcgt ttctccaact
      421 cctcgatgcg ttcacgttct ttagacgttg ctttagttgt agattttttc ttatttttgg
      481 gttcattttt cttagacaag ataggtggac atcctttcgt ttttgagagt ccatcgatcc
      541 caccctcacg gaattgacgc atccaactag cgatcaaatt agggttgttc atgttaagtg
      601 tgttggcaac ttcacgatag gacagctcac ttgttagata taactctatc gcatccagct
      661 taaattgaac agaatatttt ttcttttgtc gctttcttac tagaccctct tcaccaaatt
      721 cttgataggc attgatccag cgcttcactt gtgatggagc cttaatggaa tatttctttg
      781 ccagataatc acttccgcct ttaccatcca agtaatcatg aacgatcttt aatttaagtt
      841 caaaagtata cttagccata aaaaataccg acctccaaaa gttagatttt ttggtctaac
      901 ttttgggggt cggtacaaaa cttaaaagtt ttagaccctt ttattttctt aatgacttca
      961 gtcagttttg tgcgtaaagc gtgcgaaaca agaaaaccgc gcgtttctac gcgtggaaga
     1021 agtatcttta gcgataaaaa ctcctttcga tatactagtg agtggctacc aaccgctcat
     1081 cagatcgaaa ggagtttttt catgtcaaat gacgataaaa gtttagcata tactcgttgg
     1141 aattgtaagt atcatattat ttttacacca aaatatcaac gaaaagtaat ctatgggcaa
     1201 ttacgaaaag atcttggaaa aatacttagg aagttgtgcg aaatgaaaga tgtggaaatc
     1261 atagaagcac atgcaatgct agatcatatt cacatgcttg ttcgagtacc accaaaaata
     1321 tgtatatcca gttttatggg gtatctgaaa ggtcgtagtg cggtactaat ccacgagcag
     1381 cacgcaaatc tcaaatataa atacggaaac aaatcctttt ggtcgaagag atactatgtg
     1441 agtacagtcg gattgaatca aaagacaaat gaaaaataca tccgtgaaca agaagctgat
     1501 gatcgcattc gatatattat aagtaaaaga gagtacgtag aaccatttaa aaaataaaga
     1561 gaagtaagtg agtgaagatg agcagttggc ggtcttttaa aaatcccctt ttaaggggca
     1621 gcgagtgtcg accccttcta gggggattaa aaatacaccc gtcctcacgg gtgtatgggt
     1681 tactgataga cttgatttta actggtgtca gaaacttatg tccagaaagg gtgatgaaat
     1741 tttggcaatt tacggctatt caagaattag cacaagcaac caagattaca aaacacaaat
     1801 tcaaacatta gaaaatgctg gcgcagaaat aatcttccta gaaaatcact ggattatcga
     1861 acacctttgg aagtattttt gagttacgta agtattgatg atctgtctaa cttaatttga
     1921 caattaagag tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat
     1981 gaactaataa ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc
     2041 ataaactttt aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca
     2101 taacattgaa gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt
     2161 cttataaaca agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt
     2221 tatagaaaac attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc
     2281 agtaggttcc tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt
     2341 atttaagaga ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta
     2401 cacgtttttc tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc
     2461 aagaaccgta ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa
     2521 taagctatca agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta
     2581 ggtttagcta agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt
     2641 tttctcttaa ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat
     2701 cacaaatata aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa
     2761 tggctgtttg taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta
     2821 tagcaataat ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg
     2881 ttttcccaga taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt
     2941 gggcttgaaa atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat
     3001 tttctaaatc aagactagta tttccactag atcccactcc aaatatatat atgttttttg
     3061 attgagtgat cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg
     3121 aatagagagc ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat
     3181 gttctttttt ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag
     3241 aaaaaccaat tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct
     3301 taatatcact catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga
     3361 cttttttttc agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca
     3421 tacaaactcc tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact
     3481 cctaaatact ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag
     3541 ttattatcca aaaataataa aaaattggag cgtttaggat aatggataaa aagaggtttt
     3601 tagatcttat ttcaaaaggt ttgattgttt catgtcaagc attacctggt gaaccatttt
     3661 acaaagagga agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag
     3721 ttggtatacg tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac
     3781 caatgattgg aattattaaa agagattatc caccagaatc tccattcatt actgccacta
     3841 tgagagaagt agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc
     3901 ttagaaatcg acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat
     3961 atcctcatca gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata
     4021 aagcaggaat agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac
     4081 aagatgggcc agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg
     4141 ctgagggaag gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag
     4201 gtattgttgt gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag
     4261 cattaagtta gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc
     4321 atgttaccaa ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta
     4381 acaaatgaga gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt
     4441 ttaagtatta tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca
     4501 attggtattg ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga
     4561 gtagcttatc tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa
     4621 gatgcaacac tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt
     4681 ttacacaatc gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca
     4741 agatttattc cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta
     4801 atttggccac caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt
     4861 agtttaggaa cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac
     4921 cacaccattt accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga
     4981 tcaacaattg ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact
     5041 ggtctgttta cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga
     5101 ttaccagcag catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat
     5161 ggtgggcttt attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt
     5221 gaatatatgt ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga
     5281 ttatcttttt attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt
     5341 ttgatcgact ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa
     5401 ttaattcctt ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc
     5461 aaaaaattta aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa
     5521 gtaataaaca aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt
     5581 ggaaaagaaa atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg
     5641 aatggggaga ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa
     5701 gtgaagggtg gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc
     5761 aatcaaatat taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag
     5821 aaaaaacaag aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta
     5881 aatgatcctg tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt
     5941 tcaaaaattt atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct
     6001 attaatataa aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt
     6061 gaattacaag gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa
     6121 acctcgttgg ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt
     6181 atagttgttt ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt
     6241 gctcatggga attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa
     6301 aataagctaa ataggatatt tgtcaaatga agttggtgaa cagaaagaac tgttttcttt
     6361 ctgttcattt ttttatttta ttagtaatga ttccccatgc caaatcatga tccgtaattt
     6421 aaagttataa aagcttcgaa atccattggc atttcgttgg aataccttga tatgattatt
     6481 caaatataaa atatagagag aagagagaga gggaagatat ttataaaggg caaagttatg
     6541 tttactcaac ttaggaaata gaaatagatc aatttatatt ctcttgtcaa tcgaatatga
     6601 accttagcac tatataccaa atatagtaaa atgctgaaag atgt
//
LOCUS       DADLIO010000109         6312 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.115, whole genome shotgun sequence.
ACCESSION   DADLIO010000109 DADLIO010000000
VERSION     DADLIO010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6312
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.115"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            290..1135
                     /locus_tag="JOX41_002658"
     CDS             290..1135
                     /locus_tag="JOX41_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAY6450345.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1416..2636
                     /locus_tag="JOX41_002659"
     CDS             1416..2636
                     /locus_tag="JOX41_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HAY6450346.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2633..5353
                     /locus_tag="JOX41_002660"
     CDS             2633..5353
                     /locus_tag="JOX41_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAY6450347.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5337..6281
                     /locus_tag="JOX41_002661"
     CDS             5337..6281
                     /locus_tag="JOX41_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAY6450348.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
BASE COUNT         2355 a          977 c         1218 g         1762 t
ORIGIN      
        1 tttaaatctt ttgctaagtt gaactaatag agtcttttat gaatatcgaa gttagttttt
       61 cacctaactt cgttttttat agttggttat tataaaatag taatatagct gatttggatt
      121 caattcatat ttatttataa atcaaaaata cagagaatag tatataaatg tcctttccta
      181 ttcttaaaat gatgtttgta cttacttaaa ttaggtataa ttagtatatg ttttgtgaga
      241 aatttagact tacaataagc agtgaattta taatcaacgt ataggagaca tggatgaaat
      301 gaaactaatt ggtatagatt tagacggtac tcttttgaat tctgaccaga gcattagtca
      361 aaaaaatgca agaacaatga aacatttacc ggaagactgt tttccattca tttgttctgg
      421 aagagaagta gaagacatta ataatattct caaaaaatct ggtttaagga taccagcagt
      481 agggttaaat ggttctgttg gatttgatgg agaaaaaaag atatttgagt cttccttcga
      541 taaaaatgat gtaaaaaaaa ttgattctgt cctatcgaaa tttccaacca aaatatatac
      601 aaatctcgga agttatgaat ctcagaatta taaaaataaa atgaaaaaaa tttttcacga
      661 ggtagggagt gaattttcta tcaaagagct aaactatgag cttgagtatg aaaaatctat
      721 ttgttcaatc ccttataata atattgagga aattatagaa aaggatgcta tcagcattta
      781 caaatttttt atttttattc ctaatcgtca attgaaagct aatatattta accatttgaa
      841 aaagatgcta aatgtgtctg ttactgaatc ggcacctgta aatattgaaa tcgtacctca
      901 aaatgtatct aaaggtgtgg tgtttgatcg tttggaatca atctacaatt taaagaaacc
      961 tttgagaatc gcgatcggag atagtttaaa tgacttatct atgtttgaaa gtgcagatat
     1021 tagttttgca atgggaaata gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt
     1081 ttcaaatgat aaagacggag tatctcaagc atttgaaaga attcttacca tataaactaa
     1141 ttaaggtagt atagaacata gaattctaaa tacggaaaaa tggagcataa attccagtac
     1201 aaatagtact tcttcagtgt caaacgaagc gaatataaca tagatattta ggattgtgac
     1261 aaaaatcatg tcacaatctt tttttcgaat aaacttattt tttgaagtcg gccatttatc
     1321 gtaatttctt tgcataatac gaacaaattt tcggttattg atgaaaaaaa acattgaaaa
     1381 tggtatgata aaagaaaaaa aggaggaaat ttttaatggt gaaatttatc catgcggcag
     1441 atttacatat ggatcggtca tttgaaggac tgacaactct tgataaaact gtacaggaaa
     1501 aactattgaa gacgaatctg accgttttat caaatatcat tgaacaggca ataataaata
     1561 acgttgattt tgttttactt gcaggagata attttcatca aaatcgtcct tcattaaaaa
     1621 tacagaaaca tttttcagaa cagatgaaac ggttagaaaa gaaccatata cctgtattta
     1681 taatattcgg aaatcatgat ttctatcaaa aagagcggta ttggttctcc tttcctaaaa
     1741 atgtccattt atttacatcc gaaacggtag agacaaaaaa aataacgata aaaagtggag
     1801 aaactgtctc tctcagtgga tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga
     1861 tggaatttcc ttctagagaa ctcacagatt accatattgg gttgtaccac ggggaacctg
     1921 gcgtctctca aaaaggaaac tatgctcctt tccaaccctc aaagatgcaa gaaaagggat
     1981 acgattattg ggctttaggg catatccatg tgccaacggt cttaaatgaa aagcaaacaa
     2041 ttgtttatcc aggtgcgcct caaggtcata ctaaaaagga acaagcttct acatctattc
     2101 tactagttga attaagtaaa ggaagttgcc aaatacatcc gattaaagta gcagaggtct
     2161 attggaagac aaaggaaata tcattgagga aagcaagaac gacaaaagag gtcattgttc
     2221 acattcgtca gcagctttca aaagtagagg atggatttag tttaattgag ataaaattaa
     2281 aagattatga ccatctcaat acagatgttt tggaacggat acaatcagga gagctattag
     2341 actatttgtt agaggaattc tcagatagga taaatgattt ctttatttgg cgtatttctc
     2401 tcatagagaa tactttttat acgaagaccc cacttgctgc ttctgctaaa ttgatggaac
     2461 agttatttca atactatcag acacctcaag atttccaaca aattttaaat gaagtatata
     2521 gtcatcaaga agcggctaga atattgagcg aactgccgga atatcaagaa gaaacacttg
     2581 aaaaagccaa gcagctgctt aatcaagatt ttttatttga ggaggatcag gaatgaagat
     2641 tttaaggatc gagattgctg cttttggaaa atggcgtcaa aaaagttttg acttttattc
     2701 aggcaatcag ctgatctatg ggggaaacga agcaggaaaa tcaacgattt atcaatttat
     2761 tcaagcaata ttatttggtt tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa
     2821 agacggctca gcctatggcg gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc
     2881 tgtcgagcgc tacaagcagc aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt
     2941 gggaagtgat gagttactag aaaaactgat cgcacctttg acgaaagagt tattccagca
     3001 ggtatttact ttccagcaag agcagttgat ggaactagat catttgagag aaaaagagct
     3061 acatgatgcg ctgatttctt taggcatcac gggcagttct caagtattcc aaaagcggca
     3121 agaatattat cagaaagcac aacaattatt caagaaaaaa ggccaaaaat tactaatcaa
     3181 tcaaaaatta aatgaatgga aagagctgca agaaaaaatt catcaaaaac aagaacagga
     3241 agcttatttt ggcaagttga tccaacaaga acaggaatac gagtcgcaac agcagcagtt
     3301 attggcacaa ttaaaagagg cgaacaaaca attttcatta gccagacagc aagaacttaa
     3361 tttttcttta tatgaagaat ggcaatctct caaaaaaaac agcactacag gtcttcctga
     3421 tgagcaactt cttttagatc tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg
     3481 tttggaagaa ttagaagcaa cactggaaaa gcatagcggg atggatcagc agtcagccag
     3541 atattatttt tatttagagc aggagcagga actaaaagat ctccagcaac ttcaatttac
     3601 agcggaacaa ttaaacgaag aatggcaaag attacaaatt gagactagag aaacaaattc
     3661 agaattgaag attttggaac aaaggtggca ttggcagaaa aatccgttac cggaagaatt
     3721 tttatatgaa gaagaatgga agcatcttct ggctgaagaa agaaggattg ctgatctaga
     3781 aagccagatt tctgtgcgtc tccaaatagc taaagaacag caagagatga ttgaagcaga
     3841 agtgaatgac ttggaagaga cctatccagc attattacaa aatcagtcag agatagcacc
     3901 agtctcttca tctaaaccgt atatgctgat ggctggcgga gcaataatca ttgcaggtat
     3961 atttgtacca atgcccttga aagtgatcct tttactaatt ggtgcaggca tgattggcta
     4021 tttcttctac aaaaggcaac caaaaattaa aactaaaaat gatttctctg agataaaagg
     4081 aatgtggcaa gaaaaactag gacaacttga tctagcctta gctcaattag ctgaagcaga
     4141 agaaaaacaa aagagaactg gagaagaaaa acagattctt cagcaagaag tatatcgttt
     4201 tgcggatcat cggcacttag gaaagatgga tacgctcaaa ctcatgaaag aatatggaca
     4261 ggaagtcata gattatcaga aattatatgg cgtatttgag cggaaacata aaagagaaca
     4321 ggaaatacaa gaaaaactac gacaaatcga ccaaaaattt gagtttgtta aagaatggtt
     4381 accgatacaa gataagacaa tttcagaaaa aatggtattg ctttcccgtt ttatacaaga
     4441 gatggaacag atgaaatttg ccagaagcta tcagcaaaat actttattga agcaagaaat
     4501 caatcaattg aaaaagaaac aaaaagtatg gatacaagaa tacagcgaac aattgactca
     4561 agcaggctta tcttatcctt cggaagtacc tgtcttttta caaaaagcca aacaagccga
     4621 acagcagatg aaaagataca atgaattatc ggaaatgctt actccactat ttcctgaaga
     4681 gctgacaaaa gagaaattat ctgtaagact gcgccaactg aaagaaaagc aatcccaact
     4741 ccagcaagaa gaaaaagaag caagtgaaaa tcggcaacga ctccaacttc aagtagaaga
     4801 gttgcaaaga gacggcacat tggacgaact ttatcaacaa gctagccggc aaaaagcaaa
     4861 attacaggaa ttactggagg aatggggagc acttgaaatc gccgggacat tcttaggtga
     4921 tctttcaaca gagatgagtg aaagacaatt accccagttg ttaagagcag caggtgatta
     4981 tttaggtatt ttaacaaaag gaaattatca gaagatatta ctgaaaaatg atacactgac
     5041 tttaacagac ggatatacag aatttcccat ctatgagtta tctacaggta cgaaagatca
     5101 gctgattatg gcgatgagat ttgcttacct ctcattagaa gctaaccgtt cgatatgccc
     5161 gatcatcatt gatgatggct ggcttcatta tgatcatcag cgaaagtatc aattagctga
     5221 acttttagct aaatttggag aaaagtatca aataatttgt ttttcttctg ataaagaaat
     5281 ggtaagctat taccatgaga tgaaccaaat cgtaaaacaa ttagaaggag caaataatga
     5341 aaaaaattcg tgatttagta atcgatgagc agtttgaaca atttgtcctg atcaaaagtg
     5401 cagatgtaag aatcgctaaa aacggaaaaa aatttattgc ttttactttc caagatactt
     5461 caggtactat cgatggtaaa tactgggatg cttcggagga ggaaatcaat aaatttacag
     5521 ccggcacagt cgtttttcta aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa
     5581 agattcttca tatgcgctta acaagggtag atgagccagg agagcctagt ttatacatgg
     5641 aaagagcccc tttgaagaaa gaagaaatgg aagaagaaat caatcaattg ttgtttgaga
     5701 tcaccaatgc gcattggaat cgtattgttc gctatctact taataaatat caaaaacaat
     5761 tttttgagtt tccggcagca aaaagaaacc atcatgcatt tgccagtgga ttagcttatc
     5821 atactttgac aatgcttcac ttagggaaat caatcgccga tgaatatcct gagctgaatc
     5881 gagcattgtt gtatgctggt atcattttgc atgatttagg aaaggtgatt gaactttccg
     5941 gtcctatgtc gacagaatat acgcttgcag gaaatttgat cggtcatctg gtattgattg
     6001 acgaagaaat aactaaagcc tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc
     6061 tcgtattacg tcatatggtt ttagcacacc atggcttatt agaatatggc tcacctgtac
     6121 gtccaagaat aatggaagca gaaatattac atcaaatcga caatatcgat gcttcgatgc
     6181 agatgatgtt gacttcgatt cgtcaaacag aaccaggaaa atacaccgat cggattttcg
     6241 gtatggacaa ccgaagtttc tatgtaccaa aagatttata gcaaaaattt atttttttca
     6301 ttcaaaacaa aa
//
LOCUS       DADLIO010000110         6181 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.116, whole genome shotgun sequence.
ACCESSION   DADLIO010000110 DADLIO010000000
VERSION     DADLIO010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6181
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.116"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            127..579
                     /locus_tag="JOX41_002662"
     CDS             127..579
                     /locus_tag="JOX41_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450349.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            593..1282
                     /locus_tag="JOX41_002663"
     CDS             593..1282
                     /locus_tag="JOX41_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450350.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1407..3758
                     /locus_tag="JOX41_002664"
     CDS             1407..3758
                     /locus_tag="JOX41_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HAY6450351.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3838..4233
                     /locus_tag="JOX41_002665"
     CDS             3838..4233
                     /locus_tag="JOX41_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450352.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4558..5175
                     /locus_tag="JOX41_002666"
     CDS             4558..5175
                     /locus_tag="JOX41_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAY6450353.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5216..5515
                     /locus_tag="JOX41_002667"
     CDS             5216..5515
                     /locus_tag="JOX41_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450354.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            5549..5716
                     /locus_tag="JOX41_002668"
     CDS             5549..5716
                     /locus_tag="JOX41_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAY6450355.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(5761..>6181)
                     /locus_tag="JOX41_002669"
     CDS             complement(5761..>6181)
                     /locus_tag="JOX41_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAY6450356.1"
                     /translation="SLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGNELLD
                     TAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQKRLV
                     FKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
BASE COUNT         2129 a          850 c         1232 g         1970 t
ORIGIN      
        1 attcctcctg ctatcttttt ctattattct atcttatttg atagtagatt taaaactttg
       61 caacagaacc aattatctta tcgtagatat atattataaa tttaataaga aagcgaggtg
      121 agaatcgtga aaaaaacgat actaagtatt ttttcagtat ttacaatatt aattgggggc
      181 tattttcttt tgaatttaga ttctgttaat tcaaacgctc aaataaaaga tcaaagagta
      241 gctgaacata ataataaaaa aatgagtttg accaaaaata tctattctat gtcagatgaa
      301 gaattgtata aagaatttgg tgatttatcc ggggaacagt tagaagaaag tattccagga
      361 attagtgact cagataaaat tgttgtcttg tctgctggtg ggcaattaat gggagatggc
      421 aaatccgaat tagttagtta taaacaaaat cacagacagt ttattgatgt taatactgat
      481 tccaacgcta tttcgattaa ggatctaaaa gagcttttaa atagtaaaag aaatgaatta
      541 aagcagataa aagaaactaa ttcagtggaa ttagagtaaa ggaagattca ttatgaaaaa
      601 gatttttggt gtttctgttg ggctacttat gatgttaaca tttggaaatg cagtatatgc
      661 tgctgagaaa gaagttattt cagatccaga gcagtacgcc tcacgatact ttgctgattt
      721 tgaagaagaa gataaagtac ttgcattgcc agaaggtggt tttttaaaag gggaagctaa
      781 aattgtatct atggataatc cagatataat tcaaggttca tataattcag aaactgatcc
      841 tgcttcagtt tcagtgacag aagcaaaaaa aattgttgct gaaaaattca aaaatgatat
      901 tgaaactact ccaattatgc ctcgaggagc atttccaccc gatgttggta ctagcggaca
      961 ccttcttgta ctagcaggag gaggaagcta taaatcacag ccatttagtg gtgcgggatg
     1021 gcgttttgga ggtatgggtg taaaaccagc tgatggtaca ggcaactttt tacgttggaa
     1081 atcctacatt gacgatggaa gagtaggaaa tgtaaatcaa gccaacgcaa ctaaatctgg
     1141 ttctattcaa ggaatggcat tgtatgctcg tgaaggattc aaatactttg caccaaacgg
     1201 gcctggttgg acaatgaata taggtattta ttacacttat aatcctgttg caggtacgta
     1261 ttatgttgtt caaaatattt aataaaacag cacaaagaga tttctttgtg ctgttttatt
     1321 atttttagtt gttgacaaac actaaaatat aaaatataat caacacataa acgaacgtat
     1381 gttcggcaag aaagcagggg atttttatgg atgagatggt tttaagtact cagaaatggc
     1441 taaacaagaa atacagtaat gttacagggt ttgataaggt tccagaaaat gggcgaacag
     1501 ggtggcctac aatctatgga cttattgaag gactacaagt agaacttggt attactaatc
     1561 tagtagctaa ttttggacct accactgaaa aaatgtacga taatcaggtt actcctaaat
     1621 ggggcaaaaa tctacctaaa aatattgtat ttcttattca aggtgccttt tggtgtaagg
     1681 ggattaatcc aggtggcttc gatggggtat atactccata tttagatact gctgtaaaag
     1741 agttgcagac tgatgcaggg tttaatggaa gcgctgtaac tggagttttg gatgcgaaat
     1801 gggccaaagc gttatttgat atgagtgctt ttgttcttgt tcccggcgga gatagtaaaa
     1861 ttagaaaaat gcagcaatgg ttaaatgtaa attatttaga atacacggga ataatgcctt
     1921 gtgatggtat ttatcaaaga aattcaaatc aagcattaat ttttgcatta caagctgaac
     1981 taggatattc tcccagtgaa gcaacagggt cttatggtaa tgggacaact agtaaaactt
     2041 atcctgtgtc tgaaggtaac tcgggaaact atgtaagaat aattcaatat ggattatatg
     2101 ttaatggtta ttttgaagac ggtacattcg atggtatttt cactaaatat atgggtttag
     2161 aagtactggc attccgaaaa tttatggtat tgcctgaata tactgaaata gcagatgttg
     2221 ttgtaataaa aggactattg tctagcgctg gagatattag aagatctgca gatggcgcag
     2281 atacttctac gcaattaact agatctcaaa tccaaacatt ggttgataat gatataaaaa
     2341 tagttggtag atatcttact ggtactgttg gaattggaaa agatgaacga aataagtatc
     2401 taactacaga ggaattgaat aatatttttt ctaaaaattt atctgtgttt cctatctatc
     2461 aagatggagg tgcagcatta gcttatttta cttatgatcg tggcttatca gatggtaaga
     2521 aggctataga tgcagcaaaa aatctaaata taccattaac aacagttatt tattttgctg
     2581 ttgatctaga catgttaggg gaagaaattc ttgcatatgc tggagaatat tttaaggggg
     2641 tatctgctgt aatgtcatat agcgggtatc aaacgggtgt ttacggaaca agaaatgttt
     2701 gttctcaaat aatcaataac gggtatgctt cgtttgcatt tgtttcagat atgtcgactg
     2761 gttatagtgg gaatttaggt tttcctatgc ctagacaatg gtcttttgat caatttgttg
     2821 aatttaccat aggaagtggc aacggagctg ttggtatcga tttaatcgct acatcgggta
     2881 gagatagcgg atttaatgag ttatcaaatg atactaataa tgataattac attgccaaat
     2941 acaatcagaa ggttataaat cagatggtac gtgcgtatca atatctatca caagctggtc
     3001 ttgataatcc ttggaaccct catttgacat tttatagata tgtaaattat tctggtttgt
     3061 catgggacat catttcttct cctgtaacag agcatgatag aaaaatttat gatgaatata
     3121 ggaataaatt aactaatagc gagggcctgt ataattattt tatagatcct aatactggtt
     3181 caataatagg tttgcctcac ttaattgtga cgttacaatc acagatgttt ctagccgaca
     3241 caatcaatga tagtgtttct gactttgcag gttggttagg agatttaatg acttgctggg
     3301 gtgaagttaa gaaattagga atacaaatgg agcaaggtgt atttgcatta gtaggtacgg
     3361 ctgcaggtgg aacatttagt ctagaagatt tataccaaga tgttgacgcg gtaaatgttt
     3421 ataccttagc aaaaagaaat tctgattcaa cagctttatc ggctttaaaa acgtactatt
     3481 gtgataaggg tgctattgat agatttaatc aatttgttaa gaacagattt ggttcttcag
     3541 ataaaatcgc ttcagtaaca aatagtttat tagaaaatga cgaaacagtt gatatcttag
     3601 gtgtagggat aatttcattt ttcattgata aaatagttaa taattcactt gggacagatt
     3661 ttacttatct tgattttatt ggagatgagg ggaaagttgc aaatggattt tctgaaaaaa
     3721 ttattcaatt tcaagaaaat agaagtaaac ttaattaaga atcgtttact atttaaacag
     3781 tgtccttttc ctttttaaat atatacgata aaataagtat atgaattgta aaaggacatg
     3841 atgattatgg aagaaataga atggaataat ctgactcaaa ataataaaaa taattctgga
     3901 tgtggaatta tctttatgtt tgttatagtt ttgggaatag tagtactttt aataactgtc
     3961 aagatagtag attactttgc gaatactcct gaagaacaaa tacagagaaa acttcctgag
     4021 tttgaaagag taccacctta tgatccaaga gataattcat ttcaagtaaa aaaattaaaa
     4081 gagtctccaa atgaaatgtg gtttgaagtt acagttgaat caagcgactt caaagaaaaa
     4141 aagaaagaat acaattatat tgtaaaggca aaagtatcaa aaagatttat ttttaaccct
     4201 aaattagaaa tatatagtgt tgtaatagaa taatagtgtt aaaaaaattg taaaagttaa
     4261 agaagtcaaa ttctgatgtg aaaaataaaa tataccatgg aagacataaa agaaaaactg
     4321 gataactagt ttatttaatg gcagaccgtt aaggcctgcc atttttatgt attttagcgg
     4381 aataaatata atcatgcggg agtgtaaact tactgtttca aaaagtatac tttttgacat
     4441 gccttgattt tctttgttta tgtatggcat aataaccaca taatacaatt tgaaacgttt
     4501 ctgatttaat ctgattgttt tgaaacaatt ttagtgaaaa aagggtagat aaaaacgatg
     4561 agaaaatttt tttatatccg ggtcagtagt tatgatcaat cgatcgaacg acaactgatt
     4621 tccgcgaagg aattaggaat ccctgaagaa tatatatttg tagaaaaagc cagcggcaaa
     4681 gattttaaac gccctgaata tcaattaatg aaacggatgt ttcgaaaagg agatttactc
     4741 tatctacaat cattagatag actaggcaga aataaacaaa tgattttaga agaatggcga
     4801 gaattaacta aggaaaagca gattgatatt tctgtgttag acatgcctct gttagatact
     4861 gctagttaca agcaactaga tgggttagag acgcttatct ctgacttaat tctgcaatta
     4921 ctcagctata tggccgaaga cgagcggaaa cgaattaata gccggcaaag agaaggcgta
     4981 gaagctgcga aacaaaaggg tgtaaaattc ggcagaaaga aaattgcttt acctcctgaa
     5041 tttcctgcga tctattctga ctggaaagca ggaaagataa ctgcagtcta tgctatggat
     5101 caattgggca tgaaacgaaa taccttttat cgacgggtga aagaatatga acataccttg
     5161 caccactttt cttgatagat ataacagcta ttagacggga agggagagtt tgaaaatgga
     5221 cttaacgaat caaagggtcg tttttactgg aacgctgcag caaatgacac gaacccaagc
     5281 catcggtttg gttcactctt taaacggcca ttgtcaatca agtgttactt caaaaacaaa
     5341 tttcctggtt tgtggtcagt attctaagtc gttgtttgat gattctctct atacaaaaaa
     5401 ggaacaaacc gcgcgggact tgattgcgtt aggtcatgag attaccattt tatcagaagt
     5461 cgaattttat gcgttaatta gtcaacagtt gaaagaatgg caacggtatt tataatcgtt
     5521 agtaaaattt acaaggagga aaatttttat gaagcgaaaa tcttatgatc gttggggcat
     5581 tgaaataact agttttaatc gaaatattgc ttttcacgtg gagtgtgact gtggggaatt
     5641 agcaaaaagt gtttatcaaa aaaattactt ttactgtcct aaatgccatc gccgatacgg
     5701 ggtacatgga acatagaaac gaaatagtgc ggtagaaaag cgaatgaatg tagtatattt
     5761 ctacaaatca ttcgctttct ttattttata aatagttggt cgagagatcc cgttttcttt
     5821 tgcaatctct gcaactggaa tgccttgctt taacatgtcc accacggttt taaaaactaa
     5881 gcgtttttgc ggatctgttg agttaataga atactcgatt ggtcgtccct tatatcggcc
     5941 ggctttttga gccaataata ctccttgccg ctgacgttca cgaattttct cacgctcgtt
     6001 ttgtgcaata taacttagca gtgataaaaa catatcgaac atagcggtat ccaggagttc
     6061 atttccagta ttaaaatcta aaaactgtgc atctaatatt tttaacgcta cttttttctg
     6121 tttcataaaa gcaactgtat tttttatatc ttcataatct cttcctaaac gatctagtga
     6181 t
//
LOCUS       DADLIO010000111         5867 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.117, whole genome shotgun sequence.
ACCESSION   DADLIO010000111 DADLIO010000000
VERSION     DADLIO010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5867
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.117"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(37..684)
                     /locus_tag="JOX41_002670"
     CDS             complement(37..684)
                     /locus_tag="JOX41_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAY6450357.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(692..1378)
                     /locus_tag="JOX41_002671"
     CDS             complement(692..1378)
                     /locus_tag="JOX41_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6450358.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(1384..2457)
                     /locus_tag="JOX41_002672"
     CDS             complement(1384..2457)
                     /locus_tag="JOX41_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAY6450359.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            2679..3353
                     /locus_tag="JOX41_002673"
     CDS             2679..3353
                     /locus_tag="JOX41_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAY6450360.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            3358..4698
                     /locus_tag="JOX41_002674"
     CDS             3358..4698
                     /locus_tag="JOX41_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAY6450361.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(4847..5833)
                     /locus_tag="JOX41_002675"
     CDS             complement(4847..5833)
                     /locus_tag="JOX41_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HAY6450362.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
BASE COUNT         1771 a         1123 c         1038 g         1935 t
ORIGIN      
        1 aaaaatttca ggacaaatac acatagctgt ttctttttat tgtattcctt cagcaatcca
       61 acgagattta tagcgaaagt cttttaacaa ctcttctttt gtccaattat ttgcaatgag
      121 atccgtcaaa gtgttcatta cgagggtcat ggaaaagtat aggaaactaa ctgcttcttc
      181 cgacgattga atggagaaat gattgattct taataattcc agccattttt cgttcattgg
      241 agaatcagcc gatagttctc tacgtttggt tgtctgctga tcatttcgct gggttaacaa
      301 gtataacctt tgccaataga tactttcgtg atctaagtcg cagcaccact ctaaatattt
      361 ttcgatcccc aaaaagaaat gttgtttgtt ttcgctaatg aattttaaga tatcttgatg
      421 gactatgtga gaactgcttt tgatcgtata caaataagca tcttccaaat cttgaaaata
      481 tttataaaaa gcaccgcgcg acatccccat cttgtcaacg atttctgaga ctttgacttg
      541 gctgatgtgc tgtgagcaaa atatctccag taataggtca tcgattctct gtttctttgc
      601 gttcgataaa ttgaaaaaag tttcttttgg catccacatc tctcctttat ctctgattat
      661 acgtggatag cccttcattg tcatgaagga ttcattcctt ctttttctct tcttctgtca
      721 agtacccatc ttccattcga taaacgcgat cactccattg aatcatacgg acatcatgag
      781 taaccataat agtcgctttt tgtttctcat gagcttcttt aactagtaat ttgacgactt
      841 catatgcatg atctgtatcc aaactagctg ttggttcgtc tgctaagatc aagcttggct
      901 cattatataa agcgcgagca attgccactc tctgtctttc tccaccagaa aggtctttag
      961 gataactatt tttaagtgac tggatatcta aagattgcag caaggaatcg atttttgttg
     1021 aatcttcttt ttttgaagta acttggtcaa ctagttcaaa ttgttccttt accgttaaaa
     1081 aaggaatcaa attagagctt tggagaataa atcctatttc tttaaagcgt aaatctgctc
     1141 gttttttttc tggaagctca gttagtgagt gaccgttgat cactatttct ccggaagtcg
     1201 gtgtttgcaa tcctcctgaa atggtaagga aagtactttt acctgaacca gaaggaccaa
     1261 tgatgctgac gaattctcct tcctttacat aaaaatcaat tgctttcaaa gctgagacct
     1321 ttgtatgacc agaaccaaat gttttggtaa cttttttcat cgttaatatt tttttcattt
     1381 ttattaacct cctattgctg taattgggtc tactttggtt atcgtacgta tcgaaaacaa
     1441 tccgcctagc attgcgacaa tgatcaaaat cccactatat agcaaccatt gtgaccaaaa
     1501 aacagcaaaa ggcatcgcgc ttggtaaaat cagactagtc aaataagcaa acaaaagagc
     1561 aagcagaacg cctaccaccc caacaataaa ggactgtgct actaaagatt tagcgatgaa
     1621 gaaatttttg atcccttgtg ctttcattac tccaaaaata gcagtcttct gaagtgtcat
     1681 cacgtacatg aaaataccga ccacggcagc aaccactaag aacaaaaagt atatcatcgc
     1741 atttaaggtc atattttggg cagaatagcc aggaatactt tcaatgaatg tcccaatagt
     1801 taataactgt agacccttcg atgctttttc tttcgaaatt ttagctgaat cctttattac
     1861 gatcccattg atcggctgtt cttcttcaga agcaaacggc tgttgtccat acttcaaagc
     1921 agtccacgta tctagggacg catagatgac gggagaaact gtgtaataag tttcaggaaa
     1981 gataccgaca atcgtcaaag gatcgtcgta actgccaatt ttgatcgtat ctccaatttt
     2041 atagcctgaa tcagccagat tttgagagat gatgatttca ttctttgttt taaattcatg
     2101 ccctttcgtg agttttggta ataaaaatgc ttctttcgtt gtgccgaaaa ctgtaacatt
     2161 ttctttgttt tttcctttga ttgctccgct gtacaatccg attggtgctt tctctcctcc
     2221 ttcaatgtat ttcagatctc ctcttgttaa ttgtgaagct gcaaatactt gatttgcatc
     2281 ctccgacaaa acaatctctt gtgcgtccca atcatcgatt gcttttttaa actcttctga
     2341 aagtccattc gctagtcctg acaacatgaa tacgacatac gcaatcaaga acataatacc
     2401 gacgatcaag ccatatcgta atttagaata gcgaatttct ttgatagcta gaaacatttg
     2461 tttttcctcc ctatgataga ttgatagtga caaaatgtca cttgttgaat agtgtaactc
     2521 taaagtgaca atttgtcact tgtgttgttt ttttcttatc aataaattgt ctaagacatc
     2581 tttcgataaa accttaacat gagtcataaa aaatttattt aagccttatt tatgctttcc
     2641 atgataaact aaagtgacca aatcaatgag gtgggaaaat gattaaacta ttagtagtag
     2701 aagacgataa agtattatcc aataatataa aagaaatact cgctgcaatc ggcgagataa
     2761 cacaagttta tgatggtagt gaaggactgt tcgagttgga aagtggagtt tatgatcttg
     2821 caatcttgga tttgatgatg ccggaaatga atggatatga agtgttagca aaaatacgga
     2881 aagaaaaaat acagactcca gtattgattt tgactgcaaa agatagtttg gaagataaga
     2941 ttgaaggatt tgaacgaggt gcagatgatt atctaacaaa acctttctat cgagaagaac
     3001 tgatcatgcg cgtgaaagca ttattgaaac gctcgctagg tctctttgat gaaaatgttc
     3061 tgaagtataa ggatatcagt tgtgatttaa aaagcaatga agtcttgtat aaagaacaag
     3121 ttttgcccat acaaggaaaa gagtttgaat tgctcgttta ttttttacaa aataagggaa
     3181 tcattttgac aaaagagcag atatttgacc ggatctgggg atttgattct gatacgacga
     3241 ttacagttat tgaagtttat atgagcaact tacgaaaaca tctgcgaagt actggattgg
     3301 ataaagaaat caaaacctta cgtaatgtcg gttatatact gcaaagggtg tgatgcaatg
     3361 aatggagata ttacacgaaa gcaacgtagt cgcttttttg cgacaaatgt agcagcattt
     3421 gcttttatct tttttctttt gggattcatt actttacaga tattaaacca atctgcatac
     3481 agagaaacag atctgtcatt agagaaaata aattttgatt ctcgaacagt acaattagag
     3541 atacaaagat atcagcaagg cgatcccttt ttaaacccga ctcaaacgga acaaaacaga
     3601 acaaacatgg aacagccatt aatggaacca tcaaatgacc gttttaacac tcaagtgatc
     3661 ttgtggtcta aaaatggtga gatattgaat aaagcagcta ttggtgggcg tttcaaccaa
     3721 atcaaagaat taaaaatgga tacgaaaaat ctgaatacca tccaaaatat tgaattaaat
     3781 gaagacagtg gctcatctgc cctctctttc cgttcgatta cgaaaaaagc ggagacgaat
     3841 caagatggcg ttgcctacat ccaaatttta gaaaatacaa atcaaatcaa gaattcatta
     3901 gcgacttttc gcacgattat gattttgtgt atgattgttt tttggattct ctctattggt
     3961 atcagttatt acttgtctag tctaagcatg cgccctatta ttctttcttg gagaagacaa
     4021 aaagaatttg ttgagaatgc ttctcatgaa ttgcgcacac cgttaacgat tattcaaaat
     4081 agtttggaac atctttttac caagcctaat catactatta ttgaagaatc cgaaagcatc
     4141 gctcaagcat tgtcagagac gaggcgcctc actggattga cttcggattt gctgacaatc
     4201 gctcggaatg attctgatca gcagctgctt tcaaagcaaa tgatcaatac acaagaatat
     4261 atcgaacaac ttgttaaacc atttcaagag atggccatca tagatggaaa agagtttatt
     4321 ctccataacg atgcaacatt agaagtacca attgatgaaa aaaaaatcca tcaagttttg
     4381 gttattttgc tggataatgc attaaaatat acgaatccag aagataagat cattttggat
     4441 tcatctgtta accataaaga atggctgatt cacgtaaaga atactggccc ttctatcagt
     4501 gaagaagatc aagcaaggat ttttgatcga ttttatcggg aagatcaatc tcgggcgaaa
     4561 gagactggcg gatacgggct tggcttggca attgcaaaac aggtaatcga acagcatcat
     4621 ggacagattt ctgtatccaa ttatcttcca caaggagtcg attttaaagt ccaattgccg
     4681 ttgaagccta aaaaataatg cttatcccta aaaaagggct gtgacaaaaa tcttgtcaca
     4741 gccctttttt gttgcgaata aacggtgttc cagaagtagc ttcttcggaa ataagccgaa
     4801 atttctttaa gctgaccact tctgtcacaa cctctttagc ttacgcttac gattttttat
     4861 tgcggtcttc aatgtgtaca tcaccgcttg tgtcaatatc caattcttct cggctaacat
     4921 cttctgtcac tttttcaaca tcttcatgtt cttctttatg aatcccaact tcttcacgaa
     4981 taactgtatg tttgcttaca tctacttgct cttctttgat tgggatagta atcgtgtcat
     5041 cttccaattt ttcgtctgtt ccctgtgaag attgatctgt tactggtttg cgttcgatga
     5101 cgatttcttc acgtttgacc ggtacttcta ccgtttcagt atcgttgacc acatgtttgt
     5161 ggatgtcgac ttctccagtt gtcacatcat gtgtatttac atctaatttt tcttctttta
     5221 gttgaattgt atcatcatct agatttggtt tgcgatcgat gtcttcagtc ttgcttgtac
     5281 ccattgtatc agtctcgcca ggtacgtcca tcggatcagt tcctggtgtc atattcaatg
     5341 gatccgttgt attttgaaag cctgtcgtgc cacctacgtc cattggatct gttccagtgc
     5401 cagtttctaa tccagtcccc attgtgcttg ctgggctaac agtatcttgt gtatccattg
     5461 tatcttctgt tgtttctggc tgacgatagc cttttactgt gatgacaaat tttccatcag
     5521 aaatatctcc tctatattga tataaaggat cattttctgg tgtagccgtc tcagaatcat
     5581 aggtatcaaa agaaaaagta tcttttattt tttcccataa agaacggtct tcttcaccat
     5641 ccatccgatt ttcatctgtt tcaacatcta taccagacaa tccgtcaaat cctagtctag
     5701 atgctgcttc atcagtagta taaataacga tatcatctcg ttcataccct tcgttacgca
     5761 accgttcaat tactgataat gcttcttccc tcgtactata gcttccgatg accgttaaat
     5821 ttttctcttc catgtaaatt cctcctagca aatagattta tgattgg
//
LOCUS       DADLIO010000112         5674 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.118, whole genome shotgun sequence.
ACCESSION   DADLIO010000112 DADLIO010000000
VERSION     DADLIO010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5674
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.118"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(<1..179)
                     /locus_tag="JOX41_002676"
     CDS             complement(<1..179)
                     /locus_tag="JOX41_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAY6450363.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYA"
     gene            complement(169..498)
                     /locus_tag="JOX41_002677"
     CDS             complement(169..498)
                     /locus_tag="JOX41_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAY6450364.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            complement(575..847)
                     /locus_tag="JOX41_002678"
     CDS             complement(575..847)
                     /locus_tag="JOX41_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAY6450365.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            complement(847..1110)
                     /locus_tag="JOX41_002679"
     CDS             complement(847..1110)
                     /locus_tag="JOX41_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAY6450366.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            1344..2252
                     /locus_tag="JOX41_002680"
                     /pseudo
     CDS             1344..2252
                     /locus_tag="JOX41_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
     gene            complement(2311..4113)
                     /locus_tag="JOX41_002681"
     CDS             complement(2311..4113)
                     /locus_tag="JOX41_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit epsilon"
                     /protein_id="HAY6450367.1"
                     /translation="MGLFDFLKKKQGKVSKHVDYQLASSLFRTGKVFAEKLEVDISNV
                     DEFRKTFIAFDVETTGLNSSSDRIVEIGAVLFKEGVPIQSFGTLVNPKVRIAASASAI
                     NNITNEMLNSAPNEQEVYPQLVEFLGDALDGKITMCAHNASFDFGFLSNTFSRLGYDA
                     KIKYVDTLSLSRKHIKGIVNHKQETVAEYFGLINDTAHRAESDADICGKIFWGVLDII
                     EESLEEQKKQIEKMTPDIKELEACAFIQDIIEKKGCDTSWIRYRKNSNNYVDVTCLYT
                     FLKFKFAKKGNYIIIRKDATNGIDLPIEPCTVSEGGTTNVRVYFRSPFDLTPLSNYIF
                     SAYSDCYNSMNEYMSVSNYTKKEAEQSLSMLKSISKSAMKELLFDAKNRGYDETEVNL
                     NIEKVISREDVIINGLHNRVSLNKIRNIGNWEKGFDAGYPYWERGETARKNGKVDEAI
                     ALFDKARYNGYDAPALYDSYAKAYRKIKDYDNEILILDEGIMRKTRHDVGTLEARRDK
                     AIKLLFAKQEAERIAKEKSDFLKANKKEDAISEPSKKRGRQIIQMTDDGTIIKEFDTI
                     ASAVKEVGVNSKSIRDAANGVQKHAGGYYWKYKD"
     gene            complement(4176..5018)
                     /locus_tag="JOX41_002682"
     CDS             complement(4176..5018)
                     /locus_tag="JOX41_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450368.1"
                     /translation="MKIITINDVEYAVFAANEGTSKPQPHIIETKSGTIPEGKQLSLL
                     KEYLKQNDISPIKGATTYWCIDKVLKLDSSKEKTISETIHKQKYLSLTEENIEKQHKF
                     VGASSNYGKEGLIIHDVLNAFPLHNDLNTIAMKIAVIDVTNSTHLSQYKSRLSLYDLA
                     KVILEIPNFDDRLAKGDPQLINIIARNIGAVNMFSFASKYCTYHNVEVCGRDDYSIFD
                     GIVKNTLPHYIQGLTTNKIDTWRRSFDYEAFNECVGKLLDENNIHIPFRRRKLDHFLW
                     YANR"
     gene            complement(5034..5255)
                     /locus_tag="JOX41_002683"
     CDS             complement(5034..5255)
                     /locus_tag="JOX41_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014315041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAY6450369.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGNEIKIGN"
     gene            complement(5398..>5674)
                     /locus_tag="JOX41_002684"
     CDS             complement(5398..>5674)
                     /locus_tag="JOX41_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific recombinase"
                     /protein_id="HAY6450370.1"
                     /translation="ELIKLANKGQDYEHLADEIDELRDKRQLLLVEDASLSGENERIN
                     ELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEEHFVISFKSGIEMEI"
BASE COUNT         1737 a         1132 c          798 g         2007 t
ORIGIN      
        1 gcatatttga acccactaga ccaaatacct gataaatccc cagttttttg ttcaccctta
       61 tatggatcaa tcgcaatttc atcataaatt aaattcaaaa atttttcttt caatggcttc
      121 tcttttagct tttttaaata cttaatgaca tgttttgaag gaacgatttc ataagccaat
      181 ttctgttgcc aactcctctt tagtcattac tttagaatta gtaagtgtat cttcagcaat
      241 atctctaaag gaagaatgca ttttgttttt tctattctta aattctacaa gaatctcatc
      301 tttatcgtag ccttctgcaa ttatatcaga caaaatatct tcgctaaaat cataaaattc
      361 tttttgtggt tcaacaaatt cataaagaat accattctct accaactttg cttcaacttc
      421 gactccatta ggaacattaa aatctttagg tactgtcaac atgattgaat tgccttgttt
      481 tcttgttttt gtaatcattt aaatccctca tttctaacag tatgtaatta cttagtaaat
      541 acattatacc acgagataat gtatttacaa gtaattactg tgactcgtaa tgcgtccttg
      601 ctgaataaat ttcaaccacg tgttcatctt catctacctt ataaacaacc cggtgttgtc
      661 tattcaatct tctagaatac ctaccttcat gtgtaggttt taacttctca aatgattggg
      721 tagggagata gggatcttcc tttaaagtct gaataacctt ctcaaattga ggtttcaaat
      781 tagactgttt gattttcttt aaatcagctt tagccgagtt tttaatcatc acagaatagt
      841 tattcattat aagttatccc aatcaatttc atcaacatta gtaaatccac tatcatcttt
      901 ttctcgctta cgaacaacac ccaaagtgcc tatttgctca agtaatagcg tttctttgat
      961 tgctttccaa tcatccaaac caataagcac cgcattattt tcactgcgct cactaatgat
     1021 ttcaatttcc gtatgattct catttacatc tttcaacaac ttataaaaat ttttccgtgc
     1081 tgagctagga tttaagactg tttttgccat atctactccc cctctaattt atatctccat
     1141 tctaacgtac ttaattaagt acgtaaattc gattgttttg tttaaattgg agtaccaaaa
     1201 cagcattgta aagtgttatc cgtttccttt atacccgtgg tgctagttaa ttttttccta
     1261 gaggaaaatg tctaaacatg ttggtaaatc aacaaaaaaa cgcatagagt agtctcaaaa
     1321 ctcccaagaa atgaggacta catatgcgtt catcaaaata tactgaacat tatacagata
     1381 cttttataac attcaaggaa attatgagaa ctgtttctaa catataccac aattgtgtac
     1441 cagataagat taaaaaccga agaaatactg atcaactgaa gtaacgcgat acagtgatta
     1501 ttgcttgtgt tatatggggc ataattaatg gctatactag ccaaagagcc acgtatagag
     1561 cggtttgttc cgtcttattt cctaatggtg actttcctag taggagtcga ttcactcgct
     1621 taagttcaaa cttagcttac actatcaaga ttattcgata ctttttcatc aagaagctca
     1681 ccaaaggtga actagtcgga attatagata gttttcctag tccattatgt aaaccagtta
     1741 gaaatagaca agcaaaacta ttgaatcaaa tagccaaagt tggctataac tcaacaaaaa
     1801 aatcttattt ttatggtctt aaaattcata tgatcgttac taagactggc tttccgatta
     1861 cttactcaat cacgaatcca ggtgtccatg acgtgaaagt gttagagact ttatcggaag
     1921 aagcgaatct tcccaatatc ctaggggaca aaggatatat tagccataaa atccatgaaa
     1981 agcttgccct tatgggcatt actatatcca ttccgccacg taaaaacatg gataaatcag
     2041 aaaaactaga ccacagctta cttggaaaac aaagaaaaac agttgggact gttttttctt
     2101 ccttagaaaa attaggttgt caaaatttca actcacgttc tgttaaaggg ctagagagta
     2161 gatttgaaag catattactg gcttacagtg ttctattaag tcgagcacaa cgacgttttg
     2221 aaggaacttt gagatattct ttaggatatt aaaattaact agcaccacgg gtatctatta
     2281 agaagatcct aggttatctt agattatctg ctaatctttg tatttccagt agtatcctcc
     2341 agcatgtttt tgaactccat ttgcagcatc cctaatactt tttgagttaa cgccaacttc
     2401 ttttacagca gaagctatag tatcgaattc ttttattatt gttccatcat cagtcatttg
     2461 aataatctgt cttccacgct tcttgctagg ctcactaatc gcatcctctt ttttgttcgc
     2521 ttttagaaaa tcagattttt ccttagctat ccgctctgcc tcttgtttag caaataatag
     2581 cttaattgcc ttatccctac gagcctctaa agtaccaaca tcgtgccgtg ttttacgcat
     2641 aattccttca tcaagaatga gaatttcatt atcgtaatcc ttaatttttc gataagcttt
     2701 agcataagaa tcatatagcg caggagcatc atagccgtta tatcgagctt tatcaaaaag
     2761 tgcaatagct tcatctactt tgccattttt cctagcagtt tctccacgtt cccaatatgg
     2821 ataacctgca tcaaatcctt tctcccaatt ccctatattt cgtatcttgt ttaatgaaac
     2881 tcgattatgc aacccgttaa taattacatc ttctctagat atcacttttt caatatttag
     2941 gttaacttca gtctcatcat atccacgatt ttttgcatcg aataataact ctttcatcgc
     3001 tgattttgaa atagatttca gcatactaag gctttgctct gcttcttttt tagtgtaatt
     3061 actaacactc atatattcat tcatagaatt ataacaatcg ctataagcac tgaaaatata
     3121 atttgaaaga ggcgttaagt caaaggggct acgaaaatag actcgcacat ttgttgtacc
     3181 gccttcactt acagtacaag gttctatagg taaatcaatt ccatttgtag catcttttct
     3241 aataatgatg taatttccct tcttagcaaa cttaaacttt aagaatgtat atagacaagt
     3301 tacatcgaca taattattac tgttttttcg atacctgatc caactggtgt cgcatccttt
     3361 tttctcaata atatcttgaa taaaagcaca agcttcaagt tcttttatgt ctggagtcat
     3421 cttttctatt tgcttttttt gttcttccaa cgactcctca ataatatcta aaacacccca
     3481 aaaaatcttt ccgcatatat ctgcatctga ttccgctcta tgggcagtgt catttattaa
     3541 tccgaaatat tccgctacag tctcttgctt atgatttaca atgcctttta tatgttttct
     3601 agagagactc agagtatcaa catacttaat tttagcatca tacccaagtc tagaaaatgt
     3661 gttacttaaa aatccaaaat cgaaacttgc attgtgtgca cacatagtga tttttccatc
     3721 tagtgcatct cctaaaaatt ctaccaactg ggggtaaact tcctgctcat ttggagcaga
     3781 gtttagcatt tcattagtta tattatttat tgccgaagct gaggctgcaa ttctaacttt
     3841 tggattgaca agagttccga atgattgaat tggaactcct tctttaaata gcaccgcacc
     3901 aatctctaca attctatctg aagaagaatt taggccagtt gtttccacat caaaagcgat
     3961 aaaagtttta cgaaactcat ctacatttga tatgtccact tccaattttt cagcaaaaac
     4021 tttaccagta cgaaatagac tagaagccag ttgataatca acgtgtttac taacctttcc
     4081 ttgttttttc tttagaaaat caaataatcc cactattatt tcctccccca ttaattttat
     4141 ccagaatcac ttttacgatg cctttttctt atattctacc tattcgcata ccacaagaag
     4201 tgatctaact ttcttcttct aaaaggaata tgtatattat tttcatcaag tagttttcca
     4261 acacattcgt taaatgcctc gtaatcaaaa cttcttcgcc acgtatcaat cttattcgta
     4321 gttagtcctt ggatatagtg tggaagagta tttttaacga taccatcaaa gatggagtaa
     4381 tcatctctcc cacacacttc cacattatga tatgtacagt acttggatgc aaatgagaac
     4441 atattaactg caccaatgtt ccttgcgata atatttatca actgaggatc tccttttgcc
     4501 aaccgatcat caaaatttgg aatctccaga attactttag ccaaatcata tagagacaac
     4561 ctgctcttat attgagaaag atgtgttgaa tttgttacat caattaccgc aatcttcatc
     4621 gcaatagtat ttaaatcatt atgaagagga aatgcattca aaacatcatg tattattaga
     4681 ccttctttcc cataattaga gcttgcacct acaaacttat gctgtttctc aatattttct
     4741 tcagttaaag ataagtattt ttgtttatgg attgtttcac ttatagtttt ttctttactt
     4801 gaatcaagct taagaacctt gtcaatgcac caatatgttg ttgctccttt tattggggaa
     4861 atatcattct gcttaagata ttcttttaat aaactcagtt gttttccttc tggaatagta
     4921 ccagatttcg tttctatgat atgaggttgt ggtttggaag taccttcatt agcagcaaat
     4981 acagcatact caacatcatt tattgttatg attttcaata caaattacac ctcctaatta
     5041 cctatcttta tttcattgcc atcaggcaat ataaaagcct gcacaaactt gacacctagc
     5101 acatcagcaa tcgctttcaa ctcatctaag gttaccgttt ctcgttgtaa tttcttattg
     5161 aaattctgtg gagtctgtcc aatacgtcta gcaagttcgg aaacacttat attcatttgc
     5221 tcacacagtt ctttaatcat ttctgccgta gtcatacagc acctccaagt ttacgctaag
     5281 aatattataa atcatttggt ttataataac aatagttatt aaaatattat tataatcagc
     5341 aagcaaaaga aaacccacga ctctactgta gaatcatggg ctatttactt ctggttttca
     5401 tatttccatt tcgatgccag atttgaagga tatgacgaag tgttcttcat agactgtaac
     5461 gctctggatt atcttcctta caagcttatc atcgtactct aaggtacgga atttgttctt
     5521 gcggataaat tcaatcagct cattgattcg ctcgttctcg ccactgaggg aggcatcttc
     5581 tactaaaagg agctgtcgct tgtctctcag ctcatcaatc tcatctgcta gatgttcata
     5641 atcttgaccc ttattagcca gcttgatgag ttct
//
LOCUS       DADLIO010000113         5584 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.119, whole genome shotgun sequence.
ACCESSION   DADLIO010000113 DADLIO010000000
VERSION     DADLIO010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5584
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.119"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(488..1297)
                     /locus_tag="JOX41_002685"
     CDS             complement(488..1297)
                     /locus_tag="JOX41_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAY6450371.1"
                     /translation="MVKESVIGKKELRSIFWRSFFMQSSWSFDKMMAYGQMNGIERSL
                     RKIYPNDDDYYTALQRHTETFNITPHIAPFVMSLSVTMEEENAKNPEFDTDAINKIKT
                     GLMGPLSGIGDSFFWGTFRVIAAGIGISFAQQGNILGMILYFTLYTAIHFIFKWLATK
                     YGYVLGTKFIDDTEDNHMIDKLSHGASILGLTVIGAMIGTMVTLNTSLKFTVGGAETS
                     LQSIFDQIFPGLLPLGITFLCVWLYSKGHKTITIILGIFVLCFLGTLGGIF"
     gene            complement(1297..2043)
                     /locus_tag="JOX41_002686"
     CDS             complement(1297..2043)
                     /locus_tag="JOX41_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAY6450372.1"
                     /translation="MIQAILIALVAFLASIDEYTFGASMMGRPLFTAPFVGLILGDLE
                     SGIIIGATLESMFMGSIMVGSATPPEVYASSVLGTAIAIQSGQGVGTAVALTLPLSIF
                     LQMWRNFAYAMPITYFNNKMDEALVNHDFKKAQKYHYVAQPLIVGVPSAILVFVATYF
                     GVSTINAMIKLIPQVVLDSFDVAAGVLSCVGLALLIKMMANKAMMPYLFLGFVGVMYL
                     KMDVVGVAVVGLCLALLAVQKLTFEEEEDL"
     gene            complement(2061..2528)
                     /locus_tag="JOX41_002687"
     CDS             complement(2061..2528)
                     /locus_tag="JOX41_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAY6450373.1"
                     /translation="MIKLLRVDERFVHGQVAFAWTNNLGANCIFVASNEIATNNLRKK
                     TLKMAVPTGTKFVVKDMTEAISVLNGEKIKKYQVFLIVGTVEDAYEITQHVPEIKEVN
                     LGNLKKNENRKMITSSVYLNEQELDLVKKMTENGITVQCQAVPTDKKINPLHD"
     gene            complement(2528..2938)
                     /locus_tag="JOX41_002688"
     CDS             complement(2528..2938)
                     /locus_tag="JOX41_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAY6450374.1"
                     /translation="MRKIVIATHSMMAKGLKDTLEFIIGPQKSLLAITAYIDSDYSIN
                     QEIEQLFSDLAPDDELIVTVDLLGGSVSNAFSEQIGKDNFYLISGVNLPLLLELCLSG
                     EQDTKKLIQKAMNSGNEGIVLVNELLEKTEEDDF"
     gene            complement(2949..3962)
                     /locus_tag="JOX41_002689"
     CDS             complement(2949..3962)
                     /locus_tag="JOX41_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009141002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAY6450375.1"
                     /translation="MLGFSEERFLSVLNGAVKNIETINQVADAISEKGFKNLYLVGSG
                     GTYATISPLAYLLSTHSELDYYHEIAAEVVCSQPKKINKDTVLITSSLTGTTQETVDV
                     VKYANSQGATTIAFVGNAATPLGEIVDYAIENDADNDTLVEELQLQFFALGARLMKNN
                     GEFPEYDEFIQTLQKMPEVLLSVRQQNDQKALEFAEKHKNTEFHMFVGAGNTYGAAYE
                     YAMCVLEEMQWIATKSIHAAEFFHGTIEMTDKSMSFVLLKGEDQTRPLVDRVERFVNK
                     YSDVVTVFDTADFELAGVPSAMRQYVAPMVMATALERVSAHFEKVRDHSLDIRRYYRT
                     VEY"
     gene            4179..4913
                     /locus_tag="JOX41_002690"
     CDS             4179..4913
                     /locus_tag="JOX41_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAY6450376.1"
                     /translation="MNTEELTNKLIQDIEQEKYKYAQAIPSERDFVQIYEMNRSAVKK
                     AIQQLVNKEYLLKIHGKGTFVKKNIHEHLQIKFHGLSELLEREGIQPSSLILASEIKP
                     AGHIVGKALQLEPTEEVFHLVRLRSGDGEPISIEDTYIPLNLIPDLQAFDFQIFSFYS
                     TLAAYHYQIENIYQTISSSKVSNKEARLLKTSLNRPVISLAITAVTTNEQAVEYTEVV
                     VLPEFAAIYTKNVHQGKEMKIYAQID"
     gene            4897..>5584
                     /locus_tag="JOX41_002691"
     CDS             4897..>5584
                     /locus_tag="JOX41_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAY6450377.1"
                     /translation="MPKLINLLAYDLIDKIIAYIHEHHLTPGTKLPSERDLSEMFNVN
                     RTTLRGALQKLVDNGTLRAQTNSGYYLTAPKFEKNAHHFFTPIEDSLLSKQRLQLKAT
                     ALSPKKAAALCPELNDFKQQQPQAYLEYIDAEAISLMLLIPMETLKKSNFSDNPFQDF
                     KSLAYTRSQEISLITDNDVAADLLGVDKEEVLLFVREEIRAGKELAAIALGYTISRRC
                     NIQVNVATTLQ"
BASE COUNT         1790 a         1183 c          920 g         1691 t
ORIGIN      
        1 aagcgacaaa aaccacgagc aggtccattc atcctcaaac ctcggtgatc ttcgcggttt
       61 aacaccatca gaagaaatgc acaaaaataa taaggagagt ctgagacata aataaattcc
      121 cagactttta gtgagtctaa atccgaataa acggtgggtc gaaagcaact ctagctgcgc
      181 gtcgatcgca gcaatctcta ggtgctatgt tcggataaat ggtggtcaaa agtcagattt
      241 tcggccattt cgtaacagcc aaccagacaa aaagcgtctg ttttgtcttc tactccaatt
      301 gctcaaatct tagcgacttt tggcttggtc ttactctaaa cagtttgtaa gcctaaactt
      361 tatttgctgt ttgtttctaa gatcaaagca aaactacttt ttagttggtt acttttacaa
      421 gttcttttta ctgttgaata aatgtaaatc ttaagaacaa atatttactt ctataattcc
      481 aagtttctta aaaaattccg ccaagtgtac ctaaaaagca taaaacaaaa attcctagaa
      541 taattgtgat cgttttatgc cctttggagt aaagccagac gcataaaaag gtaattccta
      601 atggcagcaa gcccggaaaa atttgatcaa aaatactttg taatgaagtt tcagctccac
      661 caaccgtgaa ttttagtgac gtatttaaag taaccatcgt gcctatcatc gcgccaatta
      721 ccgttaaacc taaaatcgaa gcaccatgag ataatttgtc aatcatatgg ttgtcttctg
      781 tatcatcaat aaatttagtt cctaaaacat agccatattt tgtcgccaac catttaaaaa
      841 taaaatgaat ggcagtatac aaagtaaaat aaaggatcat gcctaaaata ttcccttgtt
      901 gagcaaaaga aatacctatg ccagccgcaa taacccgaaa agttccccag aaaaatgaat
      961 cgccaatacc tgataaaggt cccattaatc ctgttttgat tttattaatt gcgtctgtat
     1021 caaattcagg atttttagca ttttcttctt ccatggtgac ggacaagctc ataacaaaag
     1081 gcgcaatatg cggtgtaatg ttaaatgttt ccgtatggcg ctgcaacgct gtataataat
     1141 catcatcgtt cggatatatt ttacgtaagg aacgttcaat accattcatt tgtccatatg
     1201 ccatcatttt atcgaaggac caagaggatt gcataaaaaa ggagcgccaa aatatacttc
     1261 ttaattcttt tttcccaata acactttctt ttaccattat aaatcttcct cctcttcaaa
     1321 agttagcttt tgaacagcca gtaacgctaa gcaaagtccg acgacagcca caccgacaac
     1381 atccattttc agatacatta cgccgacaaa tcctaagaaa agataaggca tcatcgcttt
     1441 attcgccatc attttaatta ataacgctag cccaacacaa gaaagcacac cggccgcaac
     1501 atcaaagctg tccaatacaa cctgaggaat caacttgatc atcgcattga ttgtagacac
     1561 accaaaataa gtagctacaa aaactaaaat ggccgatgga accccaacga ttaaaggttg
     1621 agccacataa tgatattttt gtgctttttt gaaatcatga ttgactaatg cctcatccat
     1681 tttgttgtta aaatacgtaa ttggcattgc ataggcgaag ttacgccaca tctgaagaaa
     1741 gatggacaaa ggtaaagtca acgcaacggc agttcctact ccttgacccg attgaatcgc
     1801 aattgctgta cctaaaacac tggaagcata aacttcaggg ggcgtcgcac tccctaccat
     1861 aattgagccc atgaacatgg attccaaggt ggcaccaata ataattcctg actctaaatc
     1921 tcccaaaatc aaaccgacaa aaggcgctgt aaatagcggt ctacccatca tcgatgcacc
     1981 aaatgtgtat tcatcaatag acgccaaaaa agctaccagt gcgattaata ttgcttgtat
     2041 catattcttc ccctcctctt ttagtcatgc aaaggattga tttttttgtc cgttggtaca
     2101 gcctgacatt gaactgttat cccgttttca gtcatttttt tcaccaagtc cagttcttgt
     2161 tcattcaagt aaacggaact agtaatcatt ttccgattct cgtttttctt taaatttcct
     2221 aaattcactt ctttaatctc aggtacgtgc tgagtaattt cgtaggcatc ctccaccgtc
     2281 ccgacaatta aaaatacttg gtatttcttg attttttctc catttaaaac agagatggcc
     2341 tctgtcatat ccttcaccac aaattttgtc cctgtaggaa cagccatttt tagtgttttt
     2401 ttgcgcagat tattggtagc gatttcatta cttgcaacga aaatacaatt tgcacctaag
     2461 ttatttgtcc aggcaaaagc aacttgccca tgaacaaaac gttcatctac tcgtaataat
     2521 ttaatcatta aaaatcatcc tcttctgttt tctctagcaa ctcgttcacc aaaactatcc
     2581 cttcattccc gctattcata gctttttgga ttagtttttt cgtgtcctgt tcacctgata
     2641 agcaaagctc taaaagcagc ggcagattta caccgctgat taaataaaaa ttgtctttac
     2701 cgatttgttc ggagaaagcg ttagacacgc ttcctcccag taaatctacc gtcacaatta
     2761 attcgtcatc aggcgctaag tcggaaaata gctgctctat ttcctggtta atggagtagt
     2821 cactatctat atacgcagtt attgctaaaa gtgatttttg aggaccaata ataaattcta
     2881 aagtatcctt taagccttta gccatcatgg aatgcgtcgc aattacaatt ttcctcatag
     2941 ctcttacctt aatattccac agtccgataa taacgacgaa tatctagtga atgatcccgc
     3001 accttttcaa aatgagcact cactcgttct aaggccgttg ccataaccat tggcgctaca
     3061 tactgacgca tagcgcttgg tacacctgct aattcgaaat ccgcagtgtc aaaaaccgtc
     3121 acaacatcgc tatatttatt tacaaaacgc tctacgcgat cgactagcgg acgcgtttga
     3181 tcttcacctt ttaataacac aaaactcata gatttatcag tcatttcaat agtcccatgg
     3241 aaaaattcgg ctgcatggat cgacttggtg gcaatccatt gcatttcttc cagtacgcac
     3301 atagcatatt cataggcagc cccataagta ttcccggctc caacaaacat atgaaattcc
     3361 gtatttttat gtttttctgc aaattcaagt gctttctgat cattttgttg ccgaacactt
     3421 agtaatactt ccggcatttt ttgtaatgtt tgaataaatt catcatattc aggaaactca
     3481 ccgttatttt tcatcaggcg tgcacccaaa gcaaaaaact gtaactgaag ttcttctact
     3541 aatgtatcgt tgtcagcatc attttcaatc gcataatcca cgatttcccc gagtggtgta
     3601 gcagcatttc ctacaaacgc aatcgtcgtt gcaccttgac tattggcata cttaacaaca
     3661 tcaacggttt cttgagtcgt accggttaat gaagatgtga ttaacactgt atctttatta
     3721 atctttttcg gctgtgaaca aaccacctct gcggctattt catgataata atcaagctct
     3781 gaatgagtgc ttaacagata agctagcggg ctgattgtgg catatgttcc accagagcct
     3841 accaaataaa gatttttaaa tcccttctca ctgattgcat ctgccacctg attgattgtc
     3901 tcgatatttt ttactgcacc atttaatact gatagaaaac gttcttcgct aaaacctaac
     3961 atagttaaaa acctccaagt caataatttg aaaaatatat ttgcaaatgc cggcacatta
     4021 acaaaccact taaccttttt tatataccac ctgttaacgt ttttaatgta ccacttatag
     4081 aaaacgctgt caatagtttt taaccacttt tatttttatt tgtaccaaaa tccttttttc
     4141 atgtataata aacaaaaata gactctggag tgtaacgtat gaatactgaa gaactaacga
     4201 acaaattaat acaagacatt gaacaagaaa aatataaata cgcgcaagct attccttcag
     4261 aacgtgattt tgttcaaatt tatgaaatga atcgttcagc cgtaaaaaaa gccattcaac
     4321 aattagtaaa taaagagtac ctactaaaaa tacatggcaa aggaactttt gttaaaaaaa
     4381 atatccatga acatttgcaa atcaaatttc atggtttgtc tgaattgttg gaacgggaag
     4441 ggattcagcc tagcagctta attttagctt cagaaataaa accggctgga cacattgtcg
     4501 ggaaagcttt acagctggaa ccaactgaag aagtatttca tttggttcgt ttaagaagcg
     4561 gcgacggtga gccaatttct attgaagaca cttatattcc attaaatctc atacctgatc
     4621 ttcaagcttt tgatttccaa attttttcat tttattccac attggctgct tatcattatc
     4681 aaattgaaaa tatctatcag acaatttcca gctcaaaagt gagcaataaa gaagcccgtt
     4741 tgttaaaaac cagcttaaat cgtccggtaa tcagccttgc tatcactgcg gttacgacaa
     4801 atgaacaagc ggttgaatac actgaagtag tggttttgcc tgaattcgcc gccatctata
     4861 ctaaaaatgt tcatcaagga aaggagatga aaatctatgc ccaaattgat taatctgttg
     4921 gcttatgacc tgattgacaa aattattgct tatattcatg aacatcattt aacccccgga
     4981 acaaaactgc cttcggaacg ggacctatca gaaatgttta atgttaatcg aactacctta
     5041 agaggcgcgt tacaaaaact ggtggacaac ggcaccttac gggcgcaaac caatagcggc
     5101 tattatttaa ctgcgccaaa attcgaaaaa aatgcccatc atttctttac accgatagaa
     5161 gattctctgc ttagtaagca gcggctacag ctaaaggcaa cggctctttc accgaaaaaa
     5221 gcagcagctc tttgtccgga actgaatgat ttcaaacagc agcaaccaca agcttattta
     5281 gaatatattg atgcagaagc aattagcttg atgttattaa tccctatgga aacattaaag
     5341 aaaagtaatt tctcggacaa tcctttccaa gattttaaaa gtttggcata tacgcgttct
     5401 caagaaattt ctttaataac tgacaatgac gttgcggcgg acttgctggg agttgacaaa
     5461 gaagaggttc tgttatttgt acgagaggaa ataagagccg gtaaggagtt ggcggcgatt
     5521 gctttaggtt atactattag tcgccgctgc aacatacagg ttaatgttgc tacgaccttg
     5581 caat
//
LOCUS       DADLIO010000114         5481 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.120, whole genome shotgun sequence.
ACCESSION   DADLIO010000114 DADLIO010000000
VERSION     DADLIO010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5481
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.120"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(43..409)
                     /gene="ssrA"
                     /locus_tag="JOX41_002692"
     tmRNA           complement(43..409)
                     /gene="ssrA"
                     /locus_tag="JOX41_002692"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(580..1353)
                     /locus_tag="JOX41_002693"
     CDS             complement(580..1353)
                     /locus_tag="JOX41_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAY6450378.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            1497..1847
                     /locus_tag="JOX41_002694"
     CDS             1497..1847
                     /locus_tag="JOX41_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HAY6450379.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            1828..2544
                     /locus_tag="JOX41_002695"
     CDS             1828..2544
                     /locus_tag="JOX41_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAY6450380.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            2544..3992
                     /locus_tag="JOX41_002696"
     CDS             2544..3992
                     /locus_tag="JOX41_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAY6450381.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4062..4571)
                     /locus_tag="JOX41_002697"
     CDS             complement(4062..4571)
                     /locus_tag="JOX41_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450382.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(4561..5286)
                     /locus_tag="JOX41_002698"
     CDS             complement(4561..5286)
                     /locus_tag="JOX41_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450383.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
BASE COUNT         1864 a          955 c         1095 g         1567 t
ORIGIN      
        1 aaataaggat ttaagcatct agcgaaatct gctgaaatct cacaatggag acggcgggag
       61 tcgaacccgc gtccaaacac atcgccactt aaaaatctac gttcatagtc aactcattta
      121 aggattcact ttacagcttg ccgagtgaca ggcattctgt atcgctagtc tgatgttctc
      181 tttttcaact tacagacgga aagttgaaac gtatcccact aaagttagga cccttactcg
      241 agcacatggg cgatgccgag aggatctacg ctaactgttt ttaggcagct aaagcgtaag
      301 agttgttttc gtttttagca gttatattta actgtaacgt ttttacgtag acgtaaccta
      361 cgaaacgcaa ttcaagctcg actgtgcctg tcgaatccgt aacgtccccg ttagctaaca
      421 agggttacgt gtatttttca tacaaaatta gtatagcata tattgggata aattcaataa
      481 aaaagcgaat catatcccat tatttatata ataactgccc ctttcttaag aaaaaataag
      541 cgattttctt aagaaaagag gtagcttcaa aaaaagatct taaatcagat caaaatactt
      601 caatgcgtgg acaattccgc cttctgtatt tttctttgtg ataaaggtag aaagttcttt
      661 taatccgtca taggcgttgc ccatagcgat tttgttgtcg caagcttcca acaaggcaaa
      721 atcattcgga ccatcgccaa atccaaaagt aggaactttt tccagctgaa gttctttttg
      781 cagacgtttg acacctgccc cttttgagat tcctttcttc actgtatcga tcgagtaagg
      841 accattccga taaaaagtta gctcaggaaa atgttcgtga tagtattcgt cacctgattg
      901 agataagatc agcaacatat ttactgtgtt ttctttaaag cctaaaggat caatttccgg
      961 aacatctgaa tgaatgaagt cgtaagcatt gatcattgtt tggctatgac cggtacacca
     1021 gattttctga tcgttatagt aagaaagttc atgaccgttc aactgtacat gatcatacat
     1081 tttttgacat tcttctgaag aaaatgtttg agaatagatt tcttcgccgt ctactcgaat
     1141 gaaagaacca ttcatggtga ccgcagaagt aatgcccgca tcttccatga tagagtggat
     1201 ttctgcttct gtacgtcctg tagcgatgac ggggagaaca ttgttttctt ttaatgcgtt
     1261 catagctttt gccacttcgg gtgtgatttt tgatttcgca tctagtaatg ttccatcaag
     1321 atcaaagaaa gtgattgcac gataatttga cacaaataaa actccttttt tattggaata
     1381 agtttatctt aacaaagaat gaacaaaaga caaacctttc gtgaagaatt cctgaacata
     1441 ttggttcagt caacaattta gagtatacta taagaagaga atttaggagg gaaagaatga
     1501 tttttttcag tattggtatc ttattcttaa taattggcag tctttttcgg attctgccct
     1561 caaaaggaaa tctgcctttt tatgggtatc attcgcctct tgccgcaaaa acagacgctc
     1621 attggcggct ggctcaaaag acaagcggaa actggttttt tcttatgggc ttactgatgg
     1681 cattgatcgg ctattattta aagacatctg ggcatacgaa ttattttctg attgaaatgc
     1741 ttctgctagt atttccaatt atgcctattt ttattatgac agaaaagaaa ttacagaaat
     1801 atgacctgga aactggaggg aacgataatg aatattttaa tgattgaaga taatcaatct
     1861 gtttctgaaa tgatgcagat gtttttctta aatgaaggtt gggaagcaac tttcaagtat
     1921 gatggaaaag aagggctcga tgccttttta gaaaacccac aacattggga tatgattaca
     1981 ctagacctga atttgcccac actggacggt atgctagtag gaagagagat ccgcaaagtt
     2041 tcaagtactg tgccgattat catgctgaca gctagagatt ctgaaagcga tcaggtgatc
     2101 ggcttagaga tgggggcaga tgattatgtc acaaaacctt tcagtcctct gacgcttatt
     2161 gctcgaatga aagctttgca tcgccgtagt gagttggcag aagcaagaga agaagcagta
     2221 gtttcagatg atcattttga tatcgagact agtcatttca agatgaatac gaaaacacga
     2281 gaagcgtatc tggacaaccg gccaattgaa ggactgacgc ctaaagagtt cgatctattg
     2341 tttactttag caaaaaaacc acgtcaagta ttctctcggg agcagttgct tgaattagtc
     2401 tgggattatc agtactttgg tgatgaacgg acagtggacg cccatatcaa gaaattacga
     2461 caaaaaatcg aaaaggtcgg accacaagtc atccaaactg tttggggagt cggctacaaa
     2521 ttcgatgatt ctggtgttgc ctaatgcgtt atttgtatca gcaactctta gctttctgcg
     2581 gaatggtcgc gttgatctta ttgatcgttg gagtttcttt tacacaactg acaaaacaaa
     2641 cgattgaaga aaacaattac cagcaactgt ttggatatgc tgaatcagtt gaaaagacaa
     2701 cgcaaaccta tgccgatacg ctcccgcagt ttagtcaaga tcaggcgttt caaaatgcat
     2761 tgctgctgac agagcaagta ctgacagaac aaaatgtgaa ctttatattt atcgataaaa
     2821 acgaacgtgt catttatccg actaatacag ctttactgaa ttttacctta acagctgatc
     2881 aatggaaaaa tctgaggaat ggacgtcaag aaaaattcac atcgaataaa aatattttag
     2941 gacaagcaca ggcgacctct tacgcacttg tgccatttaa tttgaatcat gaattctatg
     3001 gagcacttgt agttagtcaa cctgcgcgaa atatcgataa cagcgttcgt ccaattacac
     3061 tgaacctgtt caaaggattt attttttcca gtatcgttgc agttattgcc agctatgctt
     3121 ttgcagcatt ccaagttaag cgtatcaatc ggttaaggaa tgcgacgaaa gaagtgacga
     3181 atggtaattt tgatgtacag ctccccgtac atgacaaaga tgaatttgat gagttagcag
     3241 atgatttcaa taaaatgacg aattcattga aagaatctca agcagaaatt gaagaacaag
     3301 aaaatcgtcg aagacaattt atggcagatg cttctcacga gatgagaaca cctcttacga
     3361 caatcaacgg acttctggaa gggttagaat acaatgcaat ccctgaaaat cagcgagaaa
     3421 acgcgattaa attgatgaaa aatgaaacag agcgtctgat ccgtttggtg aatgaaaact
     3481 tggattatga aaaaatccgt acgaatcaaa tcagtatggt cattaaaaaa ttcaatggaa
     3541 cagaaacatt gaaaaatatt gttgcacagt tagaagctaa agcagaagca gcaggagata
     3601 cattgacatt gaaagccgtt gatgatattg atgtttacgc tgattatgac cgatttgtcc
     3661 aaatcatggt caatattatt caaaacgcga tacagtttac tgaaaacggc caaatcacga
     3721 ttactttaga aaaaggctat cttgaaacga tcatcacgat tgaagatacg ggaattggaa
     3781 tgtctgaaca acaaatgaaa agtatctggg atcgttatta taaagtagat ccttcaagaa
     3841 aaaatacaaa atatggtgaa tcaggattag gtttaccaat cgtgcagcaa cttgtacgct
     3901 tgcataaagg aaaattagaa gtagaaagcg aactaggaaa aggaacaaaa ttcgctgttc
     3961 gtttgcctga cgtagaaatc aaaaaagagt aaaaaacaag cggtataaaa gatcatgaat
     4021 cgatcttcta taccgcttgt ttttactata aaatgattga tttagcccgc gggctctaaa
     4081 cgatcaatat aaggactttg agcaatagta gcatcatgag taaagagtaa gataccttga
     4141 ttttcttcat gagctaaata agaaagcaag tggagtagct cttggatctc caatacacta
     4201 agttcatcaa atgtatcttc aataacaata ttgtttcgct tggaaagcaa ggcatgaagt
     4261 aattgcagct ttactttttc aaaagacgtc aactcagctg ccgcacaatt aagcaaggaa
     4321 ggagagatat caagtttttc ttgataggcc aaacgatctt gtttgatttc tttttccggt
     4381 acatccaaca ggacatggtc tttaagattc agataaggaa acatcggcca atttttttgg
     4441 atgatcgcaa aattatccag ttttgcaaca agaacctctt ttttcaagtg ctccaatatt
     4501 ttatgctgtt tttcgagagg acacaaaata acggtcaagt gttcagcatg aatcaaatat
     4561 tcaggtttca ttacgtccag gcctcctact ttgcaaatga tggataaaaa aagtgaaagg
     4621 gaatagacta agaatgagac agcatccact gagcccaata agagtttggg caaatccctt
     4681 aagtatatct gtgaaaaaaa gatcattttg gaaatcgatg gtaaaaaaag tctgttgatc
     4741 catcggaatt gtaagtccgc ttaccgaagt caagatatca cggatatctg gcagttcagt
     4801 agtctttaag acaagaaaat tgatcctttg aagaagcgct tcataaactg actggaagct
     4861 tacgatccac aataaaacca agatacaaca aagaaagaga ggaaagaaca gctgccagaa
     4921 aataaaaagg aataatttgg ttttagaaag accagtcagg tgccaattga tcaattcctg
     4981 cttgttttgc ctgactgaat agtaaaagaa aaagataaaa aggaaggcaa atagaaaaaa
     5041 taaactgaat atgcctttta tataaaatcg gctagctaat tctaaagccg gaagaagctc
     5101 tgtagatgca gaagcgccaa taaatgaaag ccgatcttgg acttgattgg ctaaagccga
     5161 ttgcaaatgg taaagagtca ggcatgctat caataaaaaa gcagaaaagc ttgaaaataa
     5221 acaatagagt attgtctgct ttttgtaata aattaatcga gcagtagcat agcggattat
     5281 tttcatactt ttcacctcta taaaaagtat agaaaatgaa tatgaataaa gtatgaaatt
     5341 cctttagtga aatcacgaat taaaaccaga aaatattttg taaaaagcaa gaggttgtga
     5401 agaagctgcc ctattctatt accgtagatg caagcttttg aacactgttt attcgaaaag
     5461 aggagcagcg acaataattt t
//
LOCUS       DADLIO010000115         5341 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.121, whole genome shotgun sequence.
ACCESSION   DADLIO010000115 DADLIO010000000
VERSION     DADLIO010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5341
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.121"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(62..280)
                     /locus_tag="JOX41_002699"
                     /pseudo
     CDS             complement(62..280)
                     /locus_tag="JOX41_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(546..740)
                     /locus_tag="JOX41_002700"
     CDS             complement(546..740)
                     /locus_tag="JOX41_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450384.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
     gene            2092..3132
                     /locus_tag="JOX41_002701"
     CDS             2092..3132
                     /locus_tag="JOX41_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepA"
                     /protein_id="HAY6450385.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
     gene            3956..4288
                     /locus_tag="JOX41_002702"
     CDS             3956..4288
                     /locus_tag="JOX41_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HAY6450386.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            4907..5248
                     /locus_tag="JOX41_002703"
     CDS             4907..5248
                     /locus_tag="JOX41_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HAY6450387.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT         1943 a          728 c          900 g         1770 t
ORIGIN      
        1 taggtatttt tattatatat agatttaaca tatgtcggtc ggttgattga tatagctaaa
       61 gttataactc aaccgaagcc gattcatcta cacgaataaa gttgcgagtg ttctcggcta
      121 attcataaaa attgttatgt gttccatata gcaatactgg aataacttta ttttcttgaa
      181 tctcataagc aactctatac acggtgaccg catacttaaa tccattagac caattacctg
      241 ataaacctcc agttttttgc tcttacttaa atggatcaat ggcaatttca tcacaaacct
      301 atagaggatg agtgacttct gcctaattac gttaaaaaat attgaaagta actctatgta
      361 gcaaaaaata tctagaattt catttcctca aaactgatcg atattgtatc taaaaatata
      421 tactacctaa aataggtagt atatattaaa atatgtgctt ttgttagaaa aatcaataca
      481 taaattatca tatctgtata tgtcatttag gtatttcagt tatgttataa tagttttgct
      541 gtctgctacc ccggcctaat ctggcaaggg gaggaggaga tataatgaaa tacctttttg
      601 attttgtttt tgcaatcaag ccacttgcag atgtagtgtg cagttacctc tgcaaatggc
      661 ttgattgcaa aattgccaaa aaagacagta agcctacccg ttaattctat aatatagaaa
      721 cgtaaaaaaa accccatcag cctgcacgct gatggggttt ggtgatataa tgaaatacct
      781 ctttgttact cataattata ccataattag tcacgaatgc aaccaataga aaaaactact
      841 tagaacggta gatcatcgct aataacaatg cattgtccac caaatggatt ttgtgaagca
      901 ttaaatacat tgttattaat tgtcgctgct tttaactagg cctctcccct tctattataa
      961 aagaagatat atatcatttc ttaattacct actaccttaa accaaaattt aagtactacc
     1021 taatttaagt agtacttaaa caatctaaaa aatagttatc ccaattgtta tgcttttata
     1081 atacgattat ttgtaacaaa atgaatatta tataattaaa cactaccata tttaggtagt
     1141 gtttaattat tagcaaaaca aaaaatattt attctattct cttaacttca actaagttat
     1201 gctgcacacc tttatataaa tcatatgcaa ctcattagct agacaaacta caagcatgta
     1261 gttttatctg ttaattatgt actacctaaa taaagtagtt tataattagc aagtatatat
     1321 atttaaaaat ttaagattaa tttttttatg acttgtacaa atttatctga tattctctta
     1381 ttaagaacta cctaatttgg gtagttctta ttttttacat tttaagtagt atttaattgc
     1441 aatttggtag tattttttta ttatcttatt cttagaacgg tagtacttaa tataaatata
     1501 ggtagtatct aatttaagta ttaatggtag tatctaaatt aacaggtagt atgtaactac
     1561 tttaaagtaa tttttttcag attaacacag tagtatctta ttaaataagt taattttaat
     1621 ggtagtacat aattattata tatatctgac attggtagta cttattgtat tttttagtag
     1681 tatataatct attgttttct agcctaaagc cttgtcttat aagaataata taatatatac
     1741 tactgaaata aggtagtata tattactagt aatggtagta tgttttatat gcataaggta
     1801 gttcttaatt tattttttgt tttgacactg gtagtactta attatcttta attttaaaac
     1861 taaattttat tcatacgttt ttctggtagt atttaattat aaataatatt tatttaaagt
     1921 agttcttaat gactttaaag gtagtacata attcatttta tttctgattt taggtagtat
     1981 ttaattaaaa aacagtttta atgcgtttgc attttttatt tatctttgct attttcgaaa
     2041 agagtaggta attttacata aataaaacaa cgtgaaagta gaggatctac aatgactgat
     2101 tttaaatttt ttaaggcgga tagagtttac aacgaattat tttatcaatt tccaaaagtc
     2161 tttattgttt ctgacgaata caaaaaaatg aaagattcaa ctaagattgc ctatatgctt
     2221 ttaaaagcaa gattagagat cgcaatcagc aaacggcaaa tcgatgaaga aggtaatgtt
     2281 tattttactt atacgacaaa tgaactatgt agagtattaa actgccaaaa acaaaaagcg
     2341 atagcaatca aaaaagagtt ggaatccttt ggtttattat tacaaaagca gatgggattt
     2401 aacaaacagt tagggaaaaa taatcctaat agactatatc tagcagaatt aaaagtctca
     2461 gaaaatgata tctacttact cgaaaaattt gatagagaga atagggaaaa cgttgataaa
     2521 tcagagggta tgaaaatcat acccaccctc gacgaaaaat cagacgctga atcccttggg
     2581 gctcaagagg gtatgaaaat cataccgtgc caaaacgttg ataaatcaga gggtatgaaa
     2641 atcataccag aacttaataa taatatatta gacactaata gacacaatat agacactgaa
     2701 aaagaccgcc tacaagatca attgttgtta gacaattttg agacaattat gacaaacgac
     2761 agcattgcta cgtttgtccc tgaacgagta ttaaatttga taaaaacatt ttcttcaagt
     2821 tacagtgaag ctcaaaaaac cgtccagact attcataatg caaagaaaaa agctgaaata
     2881 gaaagtgata tttcgatagt ttttgaagaa ctcgatagtt attatgtcaa tgcagaacaa
     2941 gaattataca cgacactgtt aaaagcctat caaaaattaa aaaccgaaaa agtcgaaaat
     3001 atccagaacc tgatttttgt ctatgtaaaa aattggttta tcgaaaaacc aatagctgct
     3061 aaagtatcaa gtgaaaaacg tttgaattat gcaagctccc caagcactat tacgaaagac
     3121 tggttagagt gaaactttac tgacaaagtg attgttgctt catggagtaa cattaaaatt
     3181 aaaaattttt tattattcta attatattac gaatattaca aaataatagc tattttaata
     3241 gaatttataa gttaaaatat tatgataaaa atcacaaacg tagcctttta cgtcataagt
     3301 gttaaaagaa ataattaatt tcaaatatag aaaagggaac gtatgtttgc atactccttt
     3361 tttttgagtt ataataatac gcgaagagag ataatttcat tatttaaaca agctaaaaat
     3421 cttgatatta cttcttttca ggcaatacga atattattcg cttacatttt ttgtataaat
     3481 ttaattgtct gctatgcttg tgatgaattg attttcgttt tgcacttttg gatgataaat
     3541 ttggacaatt gaaaatacaa aaaaaagaaa ggcggtatga actcggaagg ctggtaacct
     3601 tcgtcagcgt tcatacacgg cattaagatt tggcccttaa tgcgttaacc tttcagtgtt
     3661 acggtattac ccgcaatgga tttagtataa cagatattca aaagtgatac cacttttttt
     3721 ggctgtgtta aggttaaaaa tacgtgatat tacgatgaat ctatgcctaa gcataatgtt
     3781 ataaaaatgt ccgtgtggct ctttgccgta tgacgaacgc tgaaattaga gggaacgcat
     3841 gtttggatgc gttccctctt ttttgtttgt catgaacgaa aatcaattct ctatttttga
     3901 aaaataacaa gaaaaacttg ttaaaaatat ttaaagaaat tgggtggttt attttatgtc
     3961 atatacagga attttgagtc tcaaagatat ttgtcactac ggtaaacggt gtaccgctac
     4021 agagaaaatc acgaagaaac tatcaactgg ccaaagtaaa accgttgtgc agtgtaagaa
     4081 atatataatc cagaaagaca aagtctcaga ggaaatgatt tattacattg ggaaacaaaa
     4141 gcaaataatt ttaaaagatc ctatcccctt aaaagagcta tatccaacaa tcaaacatgt
     4201 ttatgaccaa aacggtgtac tgattggtcg aagaaaaaat ggagtcttgc gttgtaccgc
     4261 aaaagggatg gggcgtttga tcggctgaat tgatcattct cataacttgt attttatcgt
     4321 ttttcgcttg cttgaaaata ttgtcgagac ttctaaagga acttagagtc actagaaaaa
     4381 taaggagtag acttgatcta tcaacaattc ccttcgggga gtgacggggt aggttttaac
     4441 gattggtaac gtaaaaaatt ggtcaatcga gtaaatgcgc ttgtttggat agtggtgaaa
     4501 tgaatttgtg taaataataa gcgcagagta aacaagaggg aatttagaag ttagacaagt
     4561 tagaatagcg tctagattaa tcatgagcag ctactaaggg atctagactt tgacgcaaac
     4621 tcatggaata aggagtaggt cttctcgtaa tggggaggac gcacaagaaa ttgtgtcgtg
     4681 tgctgcagta catgtagata cttgcgagga cgttgattat tggatcaatc gagcatttac
     4741 cgctgtctac tagggtttct cgtttcggac gccataaacg agtcgaaatt ttttatgtat
     4801 ttttaagtaa acgaaaaacg ataaaatatg aacaagtcct gaataaagtg aaaaaattga
     4861 tataaaacat agagaaaatg aaatttacgt aatggaggaa tgacaaatga aaaattatga
     4921 tccgaatata cgattgggca cacatactat taaggtttct ttccaacgtt gggattacaa
     4981 aggatttgtg acgtttagaa ggggcggaaa ttgtaaagga ttagatgttt tagcattaga
     5041 cgaggatgat ttatacgatc aaacattgac tgataatcca attggattcg gcttgctacc
     5101 tgaagatgat gaaggtaatg aatggtttaa aatgacgctt atgaatgata atggagacga
     5161 attatctgtt gaagatactt ggtcatattt gagtgattat attgtcagct ttgaaatcat
     5221 tgaatttgta gcggataaag aagaataaaa actggaggaa taaattttac agataaaggc
     5281 ttagaaggag tcacgacgat taataaaaag gtagtattac cttaggcatt gagtaaggaa
     5341 t
//
LOCUS       DADLIO010000116         5189 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.122, whole genome shotgun sequence.
ACCESSION   DADLIO010000116 DADLIO010000000
VERSION     DADLIO010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5189)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5189)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5189
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.122"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            137..748
                     /locus_tag="JOX41_002704"
     CDS             137..748
                     /locus_tag="JOX41_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAY6450388.1"
                     /translation="MYFILPTLYSLLCVMAPCIIYMVFFCKKNTLKHNILILIFMLYC
                     WKVFELTGTGGLTDIFYRPDTGRKFSLVQGSVNLVPFSGLNISFILNIVMCVPLGFLL
                     PIIWKSYRKIVPVFLAGALFSLIIEVSQIITTRATDIDDLIANTFGAVIGFILWAVLS
                     RVVSLKDKSSTVDYLEPYIYILIGFTGKFLLYFPFWFAFEVLS"
     gene            821..1750
                     /locus_tag="JOX41_002705"
     CDS             821..1750
                     /locus_tag="JOX41_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HAY6450389.1"
                     /translation="MKRFLKWGLVLLASLIVILMCTAVVISYVNRPYARAVYDRIKRI
                     LDKDFYDHLYLGSSFEIINLDTMDIHSYMKKDQEELPASLSKLFTIDYALSVLSLDEQ
                     ITISPTALDMQKADSSTAHLQEGDILSVYDIICAMVLPSGNDAAYSLAIYTGGKLDPD
                     AKNDEERYQSFMKNLDRYLSEQGYKHTHFTDAAGYDSNATTSAEDLTKVAAKLLKNDK
                     FAEIVAKETYRAKSIKGNVYNWNTTNQFMQQDNRYFTEGVKGVKTGSFDGRYNLCVYY
                     TSSSDNHYLLVSFGSESDSRRYVDVQNLLHNLP"
     gene            1908..2645
                     /locus_tag="JOX41_002706"
     CDS             1908..2645
                     /locus_tag="JOX41_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="HAY6450390.1"
                     /translation="MLISCGARLAPFDIRELRELMSEDELELDKIGDRKTALFVIISD
                     TDDTFNFVVSIMYSQLFNLLCDKADDVYGGRLPVHVRCLLDEFANIGLIPKFEKLIAT
                     IRSREISASIILQAQSQLKAIYKDHADTIVGNCDSTLFLGGKEKTTVKELSETLGKET
                     IDLYNTSETRSNQKSFGLNYQKTGKELMSQDEITVMDGGKCIYQLRGARPFLSDKFDI
                     TKHKNYKLLEDYDKKNLFDVEEYLKQR"
     gene            complement(2693..3871)
                     /locus_tag="JOX41_002707"
     CDS             complement(2693..3871)
                     /locus_tag="JOX41_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAY6450391.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHHYTPQTMSNMTKSFTEEVTSFKERELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILIDLQERG
                     VKNVLLFITDGLKGMAGAVQRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKKAALEARGAFAEKWKTSYPKMVESILSNDYLLTFYDFPLAIRKTIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESLERFLVSIFDTYNQKFLNRSHKGFQQVTDTLASMFTE
                     "
     gene            3894..3977
                     /locus_tag="JOX41_002708"
                     /pseudo
     CDS             3894..3977
                     /locus_tag="JOX41_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337676.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
     gene            4098..4499
                     /locus_tag="JOX41_002709"
     CDS             4098..4499
                     /locus_tag="JOX41_002709"
                     /inference="COORDINATES: protein motif:HMM:NF013068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450392.1"
                     /translation="MSDKFSKKISSDIKEDFKAIFKTASIELAGERKQLIMDKYGEDK
                     KVATACKILDEGFEDAMQVMVLPENIRQRLRTTNVLERLNEEVRRRERVVRIFPNCDS
                     VIRIIGALLMEKDDEWTSAPRKYLEFDRNEI"
     gene            complement(4706..>5189)
                     /locus_tag="JOX41_002710"
     CDS             complement(4706..>5189)
                     /locus_tag="JOX41_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010744709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAY6450393.1"
                     /translation="KEAIDQIKTAVLYPHNGLPILLMGVSGSGKTFLAEKIYEYAKEQ
                     QVIESNAPFIAYNCAQYFNFSINKIVENLTILDAMKVLRLVQKAVKELEKLMGIEFSN
                     NQLFLLYMHCCSMIERILRKESVDEQADIKEYIQKEGHNYEISKYPAYKTKFESTVIK
                     "
BASE COUNT         1639 a          879 c         1003 g         1668 t
ORIGIN      
        1 cctctaggaa aaaattaact agcaccacgg gttatgatat aataaaatgt attataggca
       61 tttttttaca agaaatagaa gcttgaagtt tatatgaagt tataaaattt aatttatatt
      121 ggaaggagga aaataaatgt attttatact acctacactt tatagccttt tatgtgtaat
      181 ggcaccatgt attatttata tggtattttt ttgcaaaaaa aataccctga aacacaatat
      241 cctgattttg atttttatgc tgtactgttg gaaagttttt gaattgactg gtacaggtgg
      301 actaacagat attttttata gacctgatac aggtaggaaa ttttctctag tacagggcag
      361 tgttaatctt gtaccattca gtggactaaa cattagcttt atattaaata tagtaatgtg
      421 tgtgccctta ggattcttac taccaatcat atggaaaagt tataggaaaa tagttcctgt
      481 tttcttggct ggggctctat tttcactaat tattgaagtc tcacaaatta taactacaag
      541 agcaacagat attgatgatt taatagcaaa tacctttggt gcggttatag gctttatact
      601 gtgggctgtt ttaagtagag tggtgtcctt gaaggacaag tcatctacag tagattattt
      661 agaaccttat atttatatat tgattggttt taccggaaaa ttcttactgt attttccttt
      721 ctggtttgct tttgaagtat tatcctgata attccataga aaataatgag tttgagttga
      781 gaaagaatat tcttgtacac aactctggaa aggaggaagt atgaaaagat tcttaaaatg
      841 ggggcttgtt cttttagcgt ctttgattgt gattctaatg tgtacagcgg ttgttatttc
      901 ttatgtgaat cggccgtatg caagagctgt ttatgatagg attaaacgca ttcttgacaa
      961 agatttttat gaccatctat atctaggttc ttcatttgaa ataataaacc ttgatacaat
     1021 ggatattcat agctatatga aaaaagacca agaagaatta cccgcctcat tgagcaaatt
     1081 atttacgatt gattatgcgc ttagtgtcct aagtttagat gaacagatta caattagtcc
     1141 tactgcactt gacatgcaga aagctgactc atctactgca catcttcaag aaggagatat
     1201 tttatctgtt tatgacatta tctgtgctat ggtcttaccc tcaggaaatg atgcagctta
     1261 tagtttggca atttatacag gtggaaaact tgatcctgat gcaaagaatg atgaagaacg
     1321 ctatcaaagc ttcatgaaaa acttagatcg ttatctaagt gagcaaggct ataaacatac
     1381 tcattttact gacgctgctg gctatgactc caatgctaca acatcagcgg aagatttgac
     1441 aaaagtagct gcaaagctac taaagaatga taaatttgca gaaatagttg ccaaggaaac
     1501 ttatagagca aaatcaatta agggaaatgt ttataactgg aatactacga atcaatttat
     1561 gcaacaagat aatagatact ttactgaagg tgtaaaaggt gtaaaaactg gatcgtttga
     1621 tgggagatac aatctatgtg tgtattatac atctagttct gataaccact atttacttgt
     1681 aagttttggt tcagagagtg atagtaggcg ttatgtagat gttcaaaatc tattgcataa
     1741 tctgccttga aatttcgtgc ctttaagcgc gtatctaaag tttctttgaa aagtttgaga
     1801 atgaagaaag tgagcagtcg aaaaacggtt gctcactttt ttgccctaaa atcgaaaaaa
     1861 tataaaaaag tcctttacaa cacgtctcag gaaaaactgc taagtcaatt ctaatatctt
     1921 gtggagcaag acttgcacct tttgatataa gagagcttag agaactaatg agcgaagatg
     1981 aactagaact cgataaaatt ggagatagaa aaactgcctt gtttgtaata atatcagata
     2041 cagatgatac atttaatttt gtagtttcaa taatgtattc tcaattattt aatctactat
     2101 gtgataaggc agatgatgtg tatggtggaa gacttccagt tcatgttagg tgtctacttg
     2161 atgagtttgc aaatatcggt ttgattccta aatttgaaaa actaatagcg acaattcgtt
     2221 caagagaaat atcggcaagt ataatactgc aagcacaatc tcaattaaaa gcaatttata
     2281 aagaccatgc agatacaata gttggtaact gtgactctac actttttcta ggaggaaaag
     2341 aaaaaacaac agtaaaagaa ttatcagaaa ccttaggaaa agaaaccata gacctatata
     2401 acacatcaga aacaagatca aatcaaaaat cttttggtct aaattatcaa aagactggca
     2461 aggaacttat gagtcaagat gaaataactg taatggatgg tggtaagtgt atttaccagc
     2521 taagaggagc aagacctttt ctatctgata aatttgatat tacaaagcat aagaattaca
     2581 aattgttgga agattatgat aagaaaaact tgtttgatgt agaagagtat ttaaaacaaa
     2641 gatagcgtaa aatattttgt gtaaataact cgtccttctg caaaataatg ggttactcag
     2701 taaacattga agctaatgta tccgtcactt gttggaagcc tttatggctt ctatttaaga
     2761 atttttgatt gtatgtatca aagatggata ctaggaaacg ctctagtgat tcttcatttt
     2821 gaaactgctc ttttctgtgg ctgtatttct tgatttgctt attaaaggat tcaatcaagt
     2881 tcgtagagta aatagtcttg cgtatggcta atggaaaatc atagaaagtg agcaggtaat
     2941 cgttcgaaag gatcgattcc accatttttg gataactggt tttccatttt tccgcaaaag
     3001 caccacgtgc ttccaatgcc gcctttttag atgacgcttg atacaccatt ttaaaatcat
     3061 cacagacttc cttacgatca tcgacacgca ctttgtgact gatattacgg gaaacgtgca
     3121 cacagcaatg ttgaaaacgg gctttggggt agaaccgctg cacggcccct gccatcccct
     3181 ttaagccatc cgtgatgaaa aggaggacgt ttttcacgcc acgttcctgg aggtctatta
     3241 aaatctcttc ccaaatcgtg atagattcag ttggtgcaat cgcatagctc aacacttcct
     3301 ttgaaccgtc cgggcgaatg ccaactgcga tatgaatggc ttccttggcg acggttttcc
     3361 gctttaaagg gatataggtt gcgtccatat aaatagcggc ataacggtca tgaagctcac
     3421 gttccttaaa tgaagtgact tcttccgtaa atgatttagt catattggac atggtttggg
     3481 gcgtgtagtg atgcccatac attttctcaa tcaagtctgc gatttccgac atggtaatac
     3541 cttttcggaa gaggtgaatg acggtctcct ctaaggtatc attcgtccgt ctataagcag
     3601 gaacagtctg ttgcttgaac tcgccgttgc ggtcgcgcgg aatctggaga tgaagttccc
     3661 cgtactcggt cttgaccgta cggtcatagg agccgttacg agaattaccc gtgttaaaac
     3721 caatgcgatc gtacttttcg taatcgagga aagccgttaa ctccgttttg agaagcgtat
     3781 tgacagcttt ttccaaatgg acacggaata attcattcaa atcgccttta ttcgctagag
     3841 tctttagaat ttctgtagta aaatcgttca tatggaagtc ctcttttctg tgaatgtgtt
     3901 gtggtaactc tattctactg aagggacttc cttttttcta tttacacaaa atattttaca
     3961 ctctcggatt gaaagaacgc ggtctttcag gagtaaagat ggtcatctcg gatgcgcata
     4021 tagggctcac aaaagctgtg aaagaatacc ttctttgtgc gagctagcag agatgccaag
     4081 cacatctcct tcgcaacatt tccgacaaat tctccaagaa aatctcaagc gatatcaaag
     4141 aagactttaa agccatcttc aaaacggcaa gcatcgagct ggctggagaa cgtaaacaac
     4201 ttattatgga taaatatggg gaagacaaga aagtcgcaac tgcctgtaaa atattggatg
     4261 agggcttcga agatgccatg caagtaatgg ttttaccaga aaatatccgt caacgattga
     4321 gaacaacgaa tgttcttgaa agactaaatg aagaagtacg ccgtcgtgaa cgtgttgtcc
     4381 gaattttccc aaattgtgat tctgttattc gtatcatcgg tgctttattg atggaaaagg
     4441 atgacgaatg gacttctgca cctagaaaat atcttgaatt tgatcgtaac gagatttagc
     4501 acattaagcc gccaatagta taatatactg gtgagaagta tcaagagacg cttcgctttt
     4561 tgctcttgac acttcttacc agcatattgg accgtagcta ggctcaacaa ggcaaaacat
     4621 cgtactttga gatttccttt ttacacaaga ttttggactt gacacagccc ctatggttct
     4681 taccttgttt atgcttattt aaatcttact ttattacagt actttcaaac ttcgttttgt
     4741 aagccgggta ttttgatatt tcataattat gtccctcttt ttgaatatat tctttgatat
     4801 ctgcttgttc atctacactt tctttgcgta aaatacgttc gatcattgag cagcagtgca
     4861 tgtaaagcaa gaacaattga ttgtttgaaa attcgatccc cattagtttt tcgagttctt
     4921 tgacggcctt ttgtaccaat ctcaaaacct tcattgcatc aaggatcgtt aaattttcta
     4981 cgatcttgtt aatcgagaaa ttaaagtatt gagcacaatt ataggcgata aatggagcat
     5041 ttgattctat cacctgttgt tccttggcgt attcataaat tttttctgcc aaaaaggttt
     5101 ttcctgaacc gcttacaccc atcaataaaa tcggtaatcc gttatgagga tacaagacag
     5161 ccgtcttgat ttgatcgatc gcttccttt
//
LOCUS       DADLIO010000117         5153 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.123, whole genome shotgun sequence.
ACCESSION   DADLIO010000117 DADLIO010000000
VERSION     DADLIO010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5153
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.123"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(52..561)
                     /locus_tag="JOX41_002711"
     CDS             complement(52..561)
                     /locus_tag="JOX41_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HAY6450394.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(673..1671)
                     /locus_tag="JOX41_002712"
     CDS             complement(673..1671)
                     /locus_tag="JOX41_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAY6450395.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            1872..2456
                     /locus_tag="JOX41_002713"
     CDS             1872..2456
                     /locus_tag="JOX41_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAY6450396.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            complement(2533..3708)
                     /locus_tag="JOX41_002714"
     CDS             complement(2533..3708)
                     /locus_tag="JOX41_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAY6450397.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            3790..4170
                     /locus_tag="JOX41_002715"
     CDS             3790..4170
                     /locus_tag="JOX41_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HAY6450398.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            4244..4606
                     /locus_tag="JOX41_002716"
     CDS             4244..4606
                     /locus_tag="JOX41_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450399.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
BASE COUNT         1684 a          892 c          958 g         1619 t
ORIGIN      
        1 aaaaaagaaa gaactcgtct aaatagacgt tttctttctt tttttgttga attattgagt
       61 aaggcgactt cttttttctg gttctttgtg tgctaatcga ctggcagcag cagcggcgat
      121 cgctccgacg atatcatcta agaaggtatg gacatgaacg ccatcgtggc tgtttagttc
      181 ttttaaaata ccaggtttca ccttgtcgat ataaccataa ttcgtaaagc cgatcgtacc
      241 gtaaacattc acgattgaca aggctaggat ctcatcgata ccgtaaaggc cttcgtcatc
      301 ttcgataata tgttgcaacg gactcatcaa ttttttcttt tctgctaata tatctaattg
      361 gattccagtg ataatggcgt tatgtacttc acgctttgtt agcacgctgt tgacactttc
      421 agtacaatcc gccaaagtca aatcagaaat atagtctttt tgtaaaaaca tgacaagttg
      481 tgcgatatct tctacagtta cgccacgttc cttcaatagt tctcttgcct tttcttctaa
      541 agtctcagtt ttgacgacca tattattgct ccccctttat tttttctttc tctatttcat
      601 gttaacggaa catgaaaaaa atgcaagaaa ctgctttcgg gtttaacttg aaatgcaaag
      661 agatataaaa aatcaactag gacgaagatt tttatcgtat aagcttgtgc tgtgaccagg
      721 ctgagttcgt tcctttggat taatatagtg taaagcgttg ttcactgcag taggtgcttc
      781 accgagccca gtagcaatca gtttcacttt tccttcatag gtacagatgt caccagctgc
      841 ataaacgcct ggaatagaag tagacatatc tgattttaca gtaatggcat ttctggtact
      901 atcaagtccc caagaagaaa gatgttctaa attagaagag aatccataat tgacgatcag
      961 agaatcaatc atcaaatcaa tcgtctcgtc acttttcact ttttttaacc ggatatctgt
     1021 cagttcccca ttattgcctg ataatccatc gatgagatag ggagtaagca agttgacaga
     1081 tgaagatttc aagcgtgata cactatgttc gtgcgcacga aattccgggc gacgatgaat
     1141 caagtaaact tcgcttgcaa taggctctaa catcaacgtc caatcgatag cagaatcacc
     1201 acctccagca atagcgactt tttttccagc atacttcatc aaatcattca cgaaataatc
     1261 caatccgtgg ttttcaaatg attcagcatt atctaaattc aattttcttg gctggaatga
     1321 accatttcct aaagctaaaa tgactgcttt ggaataatgg atgcctttat ttgtagtaat
     1381 ctcgataact tcgtcttcac gagtaagcga gagaacttct tcttttaaat ggaatgtatg
     1441 gttaaaagta gttaattgtt tttctaattg atcgattaat tcacttgctt ttattgctgg
     1501 atacccagga atatcgtaaa tatatttttc gggatacaaa gttgctaatt gaccaccaag
     1561 ttgaggtaga ctgtcaatga tttttgtttt agcttggcgc attcctgcgt aaaaagcggc
     1621 aaacatccct acaggacctg caccgatgat tgtaatgtca tagatttcca taaaaattcc
     1681 tcccttttca cactatagca gaatttaatt gagaatgctt ctcaaaaatg tttgaattcg
     1741 aaatcgaaac ggtaagttat agaatgtatc tagtgatgaa aaataaaaga aaacaaatct
     1801 agtattttta cgagaggtta ggtattatgt tattattatt atgaagtatg caaatattag
     1861 gaggaaacaa tatggcattc ccacaactag atttaaaaag tgaaaaagga ccaaaagctg
     1921 ttatcaaaac aaaccgtggt gacattactg ttcaattatt ccctgaacta gcaccgaaga
     1981 cggttcaaaa tttcattgaa ctttccaaaa aaggttatta tgatggcgtg atttttcacc
     2041 gcgttattcc tgatttcatg atccaaggcg gcgatccaac tggaacagga atgggtggcg
     2101 aaagtattta tggcgaaagt tttgaagatg aattcagtcg tgaactgttc aaccttcgcg
     2161 gagctttatc tatggcaaat tcaggtccaa acacaaacgg aagccaattc tttattgtaa
     2221 ataacacaaa tgtgccagct aatatgcttg gacaactaga aggtgctgga ttcccatcag
     2281 aaatcattga agcgtataaa ggtggcggaa ctccttggct agatttccga catacagtct
     2341 ttggacatgt actagaaggg atggacacag tagatgaaat cgcaaatgta caacgtggtc
     2401 cacaagaccg acctgtacat gatgtagtga ttgaaacaat tgaaatttca gaatagtttg
     2461 gtatggtacg gagtaattat gaaaaaggac gaaacctagt aaggtctcgt ccttttattt
     2521 tgaataaatg atttaatcga ttgtctctaa agcatacttg attcgattaa gtccttccag
     2581 taaagtttct tctggacaag caatattcaa gcgcatatgc ccatgaccgg aaggaccaaa
     2641 cgtgatgcca ggatttaata cgacttttcc tttccgaaca agagtgttct ccaattcttg
     2701 gtcgtctgaa atataggcgg taaaatctaa ccacattaag taagttcctt cagggttcat
     2761 tattctcact ttcggaagat actgttcaaa aaactgatta actgtttgaa catttttttc
     2821 tagataagga atcagttggc ttaaccattc tccacccgtc tcataagccg cttgggttcc
     2881 aatcagtcca aaagtgttga tttcgtgctg ttggttcatc actaaatgtt tttcaaaatc
     2941 agctttcatc tctggatttt tgataaatac cattgaattt ttgattgcag ctagattgaa
     3001 agtcttggtt gcggaagtaa aagcaactag tagatcatct aaattaggat caatcgttag
     3061 catggaagta aatgtatgat cgaataaagt taaatcttga tggatctcgt cactaaacag
     3121 aatcacttga tgttttaaac acaattcgct taactgtttc aattcttctt tgctccaaac
     3181 acgccctcca ggattgtgag gattgcataa aatcattgct tttacattgt tttcttcgat
     3241 ttttttctcc atgtcagaca agtccatgat gaaatgatta tttttttcta gcaaagagct
     3301 tcgaacgatg tgacgttgat ttgtttctat aatagaggaa aatggaggat aaactgggtc
     3361 atgaatcaaa atagaatcgc ctggttttgt aaaagtttgt actgctgcag ctaaactggt
     3421 taacacacca cttgtaaaaa cgatattttc tttcgtcaac tccacagcat ggtgttggcg
     3481 ttcccaatga atgatagcct gatatagttt atcagacaga gtggcataac caaagattcc
     3541 atgtttgatg tattcactaa acgctttagc taccccaccg ggagacaaga agtccatatc
     3601 tgctacccac aaaggaagta agtcatccat ttgatatgtc tcagcaattg cgtcccattt
     3661 tacactttct gtatcttttc ttgaaatctg tttatcaaat tcgatcatct taagacctcc
     3721 agtcattttc gtcgcttctt tttttgagct atttacagta taatgataaa tgcgaagaga
     3781 gggaagtaga tgacttataa aattggacaa ataattgaag gaaaagtgac agggatacag
     3841 ccttatggcg cattcgtttc tcttgataac gagacgcaag gacttattca tgtttcagaa
     3901 gtacaatccg gttatacgaa aaatatccat tcattgttaa aagtcggaca gccagtaaca
     3961 gttcagatca tcgacattga tgaatattcc aaaaaaatca gtttatcttt aagaacgtta
     4021 gaaaaaacaa atccagctgt tccatatcgc agaaaaaggt atttcacgaa taaaaatcgt
     4081 aagatcggat ttaccactat tgcggagcag ttacctattt ggatagaaga agcattatct
     4141 gaactagaac ggaaagaaaa taagaaataa aaagtgtatt ttttctgaaa atgtgctaga
     4201 atttttatgt aagccataga acaagttgat cgaggtggaa attttggcaa gcaaaagagt
     4261 tgctggtaca attatgttgc atttggagga tggtactaaa aaatttttgg tccattcaat
     4321 tgatgacaag ttggaatttg cgttagcgga actttctgaa ggaaagactg gtttagcgaa
     4381 tatacttaat ttcttaaaag aaatagttca tatcgatgtt agcaagatta gtttgatgga
     4441 attgacaaat acacatatta aagaggaaaa tgttccgttg tttgtctttg aaactgaaca
     4501 aaagaatcaa agagaagaat taggcgaagg atatatttgg gaagaaccag gtcaaatgcg
     4561 ctctgttctt ggaacttacg aagtagaggg agtgcctttc ttctaaaata cagattaagc
     4621 gaacaaagaa gtttgaattt ttttcaaact tcttttttta ttgtttggtc caaaaaatac
     4681 aatgaaatgt tctgctaaag atagtttttt agtgcatttt attttcaaaa tatgttgaaa
     4741 acggttgtat aacgaataat aataattgat cgaaaaatca tttcacaaag taatgcttaa
     4801 tttatagttg accaaggaag aaatacatga taaatttaac agcgttgatt ctgaagtgga
     4861 tgttatatca catttctaaa aaatttaaaa aatagttatt gacatgttac taacgacatg
     4921 ataagataac tgagtcgtta aaaaagaacc acttgcgaag cttgattcta tcgaaaaaaa
     4981 cttcaaaaaa gttcttgaca aataacaaac gataagttat gataaatgag ttgctgaaag
     5041 atttcgaaaa acgaaatcga aaaaaacttt taaaaaagag ttgacaatcg cttgtctctc
     5101 tgatatgata taaaagttgc tacggcagcc aaaaacgaat cgggaaacac tcc
//
LOCUS       DADLIO010000118         5099 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.124, whole genome shotgun sequence.
ACCESSION   DADLIO010000118 DADLIO010000000
VERSION     DADLIO010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5099
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.124"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(73..1221)
                     /gene="nagA"
                     /locus_tag="JOX41_002717"
     CDS             complement(73..1221)
                     /gene="nagA"
                     /locus_tag="JOX41_002717"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HAY6450400.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1297..2133)
                     /locus_tag="JOX41_002718"
     CDS             complement(1297..2133)
                     /locus_tag="JOX41_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAY6450401.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2317..3534)
                     /locus_tag="JOX41_002719"
     CDS             complement(2317..3534)
                     /locus_tag="JOX41_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAY6450402.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            3917..4000
                     /locus_tag="JOX41_002720"
     tRNA            3917..4000
                     /locus_tag="JOX41_002720"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3951..3953,aa:Leu,seq:gag)
     gene            complement(4240..5096)
                     /locus_tag="JOX41_002721"
                     /pseudo
     CDS             complement(4240..5096)
                     /locus_tag="JOX41_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337154.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1579 a         1044 c          811 g         1665 t
ORIGIN      
        1 ttttactaga acacaaaaaa aaccttaaaa ccaaacttaa gaagtttagt tttaaggtta
       61 acttaaatta tattatgcgt ggaaacgttc cacgccatct agataagttg cttccaatgt
      121 catatcaggg ttcaatacga taaagtctgc atcgcgtcct tgagcgattt ttccacatgt
      181 atcatcgatt ttacagctga ttgctggaat cagactagcc atcatgactg cttgttctgg
      241 tgttgctaat ccccagtcta caacattttt aattgcttct ttcaatttca atatacttcc
      301 agctaagttg ccagattcta gacgtgctgt tccttctttt actactactg gaaattcgcc
      361 taaattgtaa tttccatcag gcatcccacc ggccatcata cagtctgtaa ttaatgcgac
      421 atgatcatgt cctgcttttt ccattaggat tcccgcagca tttggatgta catgatggcc
      481 atcacaaatc aattcagaaa agacatgttc taaagataat aacgcaccca ccatacctgg
      541 ttcgcgatga ttcaatccac gcataccatt gaaagcatgg acaaatacac ttgcgcctgc
      601 ttcaacagct ttttgcgctt cttctagtgt agcattactg tgtcctagag aaacaactac
      661 tccttcttca gtcacttgtt tgacaaactc ttctacacct tgacgttccg gtgctaaagc
      721 aatttttttg attaaaccac ctgaagcttc ttgccattca tggaaagtat ccaaatcagg
      781 atccccgaaa taacttgggt tttgtgcccc tttgtgttct tctgtgaaga aaggaccttc
      841 aaaatagatt cctttgattt tagctcctgg tgcttcctga tacattttgc cgattgtctc
      901 agctacatct tttaaacgtt ctttgcttga cgtcaatgtt gttggtaaaa atgaagtcac
      961 tccacaagat aacagacctt cagacatcac tttgatgcct tctgcatcat tatccattac
     1021 atcatgattc atatagccgt gaatatgtgt atctaccaaa ccaggagcaa tccatttgcc
     1081 gctttggtca atgatgttga cttctccctc aggtagttct ttggtgtatt caccaaaaag
     1141 tccatcggta atttcaagat agcctgcatg tttgacacct gacgctaaaa agaatttgtc
     1201 agcatagata aaagttctca ttctattctc tccctttgtt tttctacctc taaagtactc
     1261 ttatttagag aagaagtcaa gaatggtcta caccatttac aaattttttg aaatttgttt
     1321 cacagcttgt gctaagcctt catagaatgc tgctctttct ggttcttctt tacgcttgta
     1381 tattaagctt ttaagcacaa ataaatcatt gaggtaatag tagctattct tctcttgagc
     1441 ccaatagatt ccttgattca cctgttctaa cgcttcgtcg atttcatttt gatggaataa
     1501 gaaatttcca taattataaa aaatttgcga aaattcactt tttgatcgtt catcagctga
     1561 ttgatgcagc agttggatgc ttcgactcaa atagtagcgt gcttcagccg tttttcctgc
     1621 cacaccatat atttttccga tacaactaat cagttgtatt tctgtgtcag aaacatggat
     1681 tctttctttt tggctagagt agcttaatgc ttctttcaaa taataaaggg actgagagat
     1741 attttgacgc aacgtgaatt cgcaaacacc gagataataa taatagcgtt gaaagtcagt
     1801 tgcttgatac agattttcag aaatatcaga agattttagt acttgttcta acttccgata
     1861 atcacgtttt tggaaacaac tatccaacag ttcaaataat ttatcgtttg tccgagtagt
     1921 ttttcgagag agattcatca catgatcaat cgttacccct agccgttgac aaatctgcat
     1981 catcaccaat acattcggca gttcctcatt attttcgatc cgacttaata cactttgtga
     2041 acaaatatca tgcgaaagca ttttttgcgt cattttttgt tcttttcgaa tctctttaat
     2101 gatcgttcca aaggactcga ttaacgtttc cataagtatc ctccccaaaa tatgcgtatt
     2161 cgcattctat tcgtatttta ctttaggaag tcgcaaactt caagaaaaga cttgcaacta
     2221 aataatatac tttagttatt taagaaaact ccactagaaa gagagcctca gtgtgtttgt
     2281 ctgtggccct cctactgaaa aatttggttt ttaaaatcat ttttggcgat aggttgctag
     2341 gaattctctc attttcttag ctgtttgttt caaatcatcc attttaggaa gataaacgat
     2401 tcgaaaatga tctggctggt tccaattaaa tccaccacca tgtacaagta gaatatgatg
     2461 ttcatgtaaa aagtccaaaa cgaatttttc atcatccaaa atattgaatc gctttgtatc
     2521 aatttttggg aatatataaa aagcagcttt tggttttacg gctgaaagac caggaatatc
     2581 attgattgca ttatagatat attctctttg ttcatagatc cttccgcctg gcaggagcag
     2641 ctcatcgaca ctttgataac cgcctagcgc ggtttggata atttgctgag acaatacatt
     2701 ggaacacaaa cgcatggagg acaacatatt cagcccttct atatagcctt tgacgtgtga
     2761 cttatctcca cttaggacca tccagcctac tcgaaatcct gctacacgat gagatttgga
     2821 tagaccgttc agcgtaacaa cgaacaaatc aggcgctaat gtagcaatcg gaatatgttc
     2881 tagaccatcc atcactaagc gatcatagat ttcgtcggaa taaataatca ggttattttg
     2941 tcgagctact tcaacgattt cttctaataa ttcttttgga taaagtgccc cagtaggatt
     3001 attaggatta atgataacaa tagcttttgt ccgactcgtt atttttgatt tgatatcatc
     3061 aatatcagga taccattctg cctcttcatc gcaaatataa tgaacaggtg tgcctccagc
     3121 taatgcaata gaagccgtcc acaacggata gtccggcatt ggaaccagta cttcatctcc
     3181 attgtccagc aacccctgca tacacatcgt gatcaattcg ctcactccgt tgccggtgta
     3241 gatatcattg atcgtcacat tcggaaaatg tttcagttgg caatattgct caattgcttt
     3301 tctagcagaa aagatcccct tggaatctga gtagccttct gagtcacggg cattcatgat
     3361 caaatcacga atgacttcgt ttggtgcttc aaatccaaaa ggtgcgggat ttcccgtgtt
     3421 caattttaaa atactaatgc cctcttcttg catccgctcc gcttcttcta gaacgggacc
     3481 gcgaacatcg taactgacac cttctaattt gttggatttt tcaaattctc tcatcactta
     3541 gccaatccct catttcaaaa agttagaact ttccaaattt tttgttattt actatttcaa
     3601 tatcatactc catcctagaa aattttgcca cttatttagg aaaaacgtaa gtattaaaaa
     3661 aacacaaaca agcgttgaga acttaattgt catgatagtc attccataga ttcgctgccc
     3721 aatccattgc aattccacaa atgattccta gcataaaacc aagcaaaaaa cgtccgaatg
     3781 caagtccaat caatacacct aagatcattc ccagtcctga aaattctccg tcatatttct
     3841 ccatcttaat aagtcctccc atttttgagc ttgacaacta tgtaaaacct cgctatcatt
     3901 agtgtgttat tattacgcag atgtgttgga attggcagac aagcatgatt gagggtcatg
     3961 tgagcgttag ctcgtgtggg ttcgagtccc atcatctgca ctacaactcg tgaagttaat
     4021 tttgcttcac gagttttttt gtttgaacgt ttctttatgc cattatatac atatcactgt
     4081 atcctttaca aaaagaacgt acaatcatgt aaacagcctg aggtgagtat atgaaggtcg
     4141 gaaacaagct actcgtagaa acttgcaagt gttaaaacaa ttaatcgaaa aacgagtaaa
     4201 atccctcacc taacactaaa gcgagggatt ttttgtatat tatctgttta tcaccgttat
     4261 tataaaggta caaataccaa gcacggttaa tccaaattgc ataaattcat ttttttgtac
     4321 actcatgctt ttcattagct ctttaactgc cattagtact aagatggcga taacaacata
     4381 aagtatatag tacgtccgca ttccggaagc ccatactgtg ggagaaaatc ccataattaa
     4441 ccttgaacaa aatcccatta tcatcaaaat aactaaaaaa atagaagttt tcttattgtc
     4501 aaaacttaaa taaattccaa caattaaaca tagtaataat gccaagacta ctaaagtagc
     4561 tatccaagta cctggataaa aaagtgacag tttcgttcct aactctgtaa agagattatt
     4621 caggttacta ctactccaaa tcattgccct tttatttcca ttgacgtaag taaagctttg
     4681 acccattgta ttaccaaaat aaataatcag gtttaagaaa aacggtaatg cagtcaatat
     4741 acgcacataa tagttttgac atttcctata tgttagaagg aaaattaaga aaaatagcaa
     4801 taaaaataag atattcatgt ctaaaaaaac ggctttccaa atgatgaaat acctaaatct
     4861 aacttattaa gaaagttgaa atttttatat tcaggaaacc atttattaat ttcatgtgca
     4921 gcacgtaatg cattccctgg agttgtcaaa gagaaaatta attctgctaa gcttattatt
     4981 gaaaatactg ataacttata attatatcgt ccattgacaa tcaaatataa actaactata
     5041 cttgttagaa caaaaaaaca ggcgttgact tgttcttgat tagttaaaaa tatcaataa
//
LOCUS       DADLIO010000119         5088 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.125, whole genome shotgun sequence.
ACCESSION   DADLIO010000119 DADLIO010000000
VERSION     DADLIO010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5088
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.125"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(205..660)
                     /locus_tag="JOX41_002722"
     CDS             complement(205..660)
                     /locus_tag="JOX41_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450403.1"
                     /translation="MKKQLFKTFLLSTSILTFGSAITPSGAVFANENNISDIATYSDD
                     EYYYVLDEPVIQTRTWSKPQSWSIAKGSRTYLGIETHSRGTKLSVSANVFGMKIEIAR
                     NTSASGKFKKYRQNARITVTYRVYRKVDNKYIRTQTSTANTQYIDYIPA"
     gene            complement(1269..1685)
                     /locus_tag="JOX41_002723"
     CDS             complement(1269..1685)
                     /locus_tag="JOX41_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450404.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDVNNYSEAIRFLCMSY
                     EPDTNTITTSNQAKLNAMGKEISIMTEIMAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSGNFDPTNFLKR"
     gene            complement(1687..1968)
                     /locus_tag="JOX41_002724"
     CDS             complement(1687..1968)
                     /locus_tag="JOX41_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450405.1"
                     /translation="MDILVRNINPKIIARIDKRCQELTTKTGKKWSRNKYLKVLIESD
                     FDRQLMNYKKDQFDLLLEKFIAIQTENTNILNDYVHTNNQLIETLIGGI"
     gene            complement(2415..3383)
                     /locus_tag="JOX41_002725"
     CDS             complement(2415..3383)
                     /locus_tag="JOX41_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAY6450406.1"
                     /translation="MSNEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKSDIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGFA
                     YFSKEDFHELLDIPKSYNQGTIDQRVFNPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKSDDFNKHAPTKEEQNKALELANQQVQSEKAPTSLQEKIKEQKRKLELL
                     QQLEKLEREQNTQNKENNAQKSEINSDIPSELKKDLLDNLQNLFKD"
     gene            complement(4724..>5088)
                     /locus_tag="JOX41_002726"
     CDS             complement(4724..>5088)
                     /locus_tag="JOX41_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAY6450407.1"
                     /translation="FSVLFLINILNTSFSEGINPNEVNGSLLLFFLNAATYGAFLEEG
                     IFRFCMIDPQANKKQQYISILISSFLFSIVHGGGLSIFFIGIILSFVYIQTKNIWYSI
                     VAHGFYNTIGILIYLISI"
BASE COUNT         1595 a          839 c          839 g         1815 t
ORIGIN      
        1 aaaaaaaact atatttaaag agttttttta gatttacttc tttgaattca cgaatgaagg
       61 tagaatgaaa tagtataatt attagcacta aaaaaaatat atcactatgt tcaaataaaa
      121 aatatatatt tgacggtact cctaatgatg ggatagcaaa ggtcaaaacc aagtaagcaa
      181 tactaattat ccattttatt gtcattaggc aggaatataa tcaatatatt gtgtatttgc
      241 tgtagaagtt tgagtacgaa tatatttatt atctacctta cgataaactc tgtaggttac
      301 agttattctt gcattttgac gatatttttt aaattttcca cttgcagaag tgtttctggc
      361 tatttcgatt ttcatcccaa atacatttgc actgacagat aactttgtac ctcgactatg
      421 agtttctata cctaaataag tacggcttcc tttagcaatt gaccagcttt gaggtttaga
      481 ccaagtcctt gtttgaataa ctggttcgtc taacacatag tagtactcat catcagaata
      541 agtggctata tcagaaatgt tgttctcatt agcgaatacc gctccgctag gagtaatagc
      601 agaaccaaaa gttaaaatag aagtagataa taaaaaggtt ttaaataact gttttttcat
      661 caaaatcacc tcgaatataa gatacttaag aaaacgcttt ctttatataa ttagaataat
      721 caggaaattt aatgttgtca agagggttta ttttataaaa gctgttatat taaaggttag
      781 tagacataat gtacactatg ccaagtagcc cctctaccaa tggatagaga cgctcacttt
      841 gtgatttcta attggtctag cttaaacact tcagccaatg cttgatttta tgcacttttc
      901 ttttttcatt tctttgtgca ttttgaccgg tcatttttta gagatttgtt atttttgtga
      961 gcatttgata tgctcttttt atacctcaat ctcttctttt ctaatgttaa tgaataggat
     1021 aatctcattt ttagctgctc gtgagagcag tctttttttg tttcagggta cgtcctattc
     1081 tttggatttc cgcgctatta aataaccgat acttggggat tggggtagcg ccccaaaata
     1141 caaaaagaag aagttgcata agcggatttt tctttttttt cgcaagttgg taccaacttg
     1201 caaatcttgc tggaagactg atccctaaaa agaaatcgag gaattttttt agggatcggt
     1261 ttcttttttt atctttttag aaagtttgtt gggtcaaaat ttccagaagt aaaggtttga
     1321 ttggtttctt tttgacgatt tttgggttga tttcgtcggg aaggattgag ttgattttca
     1381 attttttctt tcacttcttg atacacttta gaatttgtac cgataagaac accagtatct
     1441 tttagatata aatcagcaaa ttctgccatg atttctgtca tgatagaaat ttcttttccc
     1501 atggcattga gttttgcttg gttactggtt gtgattgtat tggtatcagg ttcataactc
     1561 atacataaaa aacgaatggc ttctgaataa ttgttgacgt ctggattttt ttcgatgatg
     1621 gaatctaaaa cgtcaacgtg actgggataa agggttacgt gtttttgaac agaagttttt
     1681 ctcatgttat attcctccga taagtgtttc aatgagttgg ttgtttgtgt gaacatagtc
     1741 attcagtatg ttcgtatttt ctgtttgaat ggcaataaat ttttcgagta ataaatcgaa
     1801 ttgatctttt ttgtaattca taagttgacg gtcaaaatca ctttcgatta gaacttttag
     1861 atatttattt cgactccatt ttttgcccgt tttggttgtg agttcctgac aacgtttatc
     1921 tattcttgca ataattttgg gattgatatt tcgaactaaa atgtccatgg aaattttcct
     1981 ttcgtatcag cgtataattt atgtatatca tacaaatata gtatttgtat agctattttt
     2041 cgccaaaaca ctatacatag cctagccaca atggcaaaaa agtgatagca aatttttttc
     2101 tgagaaacgt gataggcaca gcctatctag caccttttgt aagaaagtga taccacgttt
     2161 ccttatgctc tttcaaaatt cagaaaaatc agctgtaaaa cgagtgcagt ccgagtaaga
     2221 ttcaacgaaa aaacggggat tggggcgcca ccaaaatatc gcaacatggg tccatgttgc
     2281 tctgctcgca aaagcaaaaa gaagaataaa accagcaatt taaattaata aaaattgctg
     2341 gttttattgc cagaattgcc accatttttt ctccgtcttt gattgttttt tctgtcataa
     2401 aatctaaaaa cccctcaatc tttgaataag ttttgaagat tgtctaataa gtcttttttt
     2461 agttctgaag gaatatcgga atttatctct gatttttgtg cattattttc tttattttgg
     2521 gtattttgtt ctctttctaa cttttctaac tgttgtaaaa gttccaattt tcgcttttgt
     2581 tctttgattt tttcttgtaa tgaagtaggt gctttttcag attgaacttg ttggttagct
     2641 agttctaatg ctttgttttg ttcttctttt gttggggcat gtttgttaaa gtcgtctgat
     2701 ttttttatct caggtttaaa tgtaaattga tagccaatga caggctttcc ccgtcctttt
     2761 ccgtatttct ttttgattgt taaaccttta aagattgcag ttagttcttg tcgtattgga
     2821 ttgaacacac gttgatcaat cgtaccttgg ttgtaacttt taggaatatc aagtaattca
     2881 tgaaagtctt cttttgaaaa ataagcgaaa cctttggttc tgtattgttt tagtaatcga
     2941 aacattgttt ttgaataact gctttctaat tcattgaatt gttggagaga atagcgcacc
     3001 cattcttcaa gattattaag taagggtaag gctttttcat gaacttgtat ttcagcaaaa
     3061 ggaatatcag attttccgtc gattttaaat tgattaaata aaacaaaacg ttcacgttgc
     3121 aaaccgtcag cacttcttct accaaaacgt aaatccatta atttgtcata cgttgtttct
     3181 aaatcatcta tgaatcgaac atttgcagtt gctttataat tgcttaaatc ttttaattgc
     3241 tcgaatgtaa attgtacttt tttatcacct acatcacgca ttcttgatac gatagaaaag
     3301 aacaaattca tttcgactgg tgtaaatttt cgcaacggaa ttgtatttaa ttcatgatga
     3361 tactttacga tttcattaga catatttaaa atagctcctt tcttactcgc acaagagata
     3421 cacgttatga aatacaaaat gcctatttat ctacatctta tattaacatc gtcgatgtac
     3481 taattcaatg tacaaacaga caaaacgatg tagataaaca gacaaaacga tgtagataaa
     3541 cagacaaaac gatgtagata aacagacaaa acgatgtaga taaaagcgtc attcccttgg
     3601 gagagtaagg atatagccga cggtaaagag gtttaaaaag aggtttaaaa agagattata
     3661 aaagaggggg acaaaatttc ccgcctaaaa aaccacttct tttttctcca aacagattcg
     3721 cgcatttttc tcaactggga atcttactcc ctacagtcgc ttaaaaaggt gtgatcgctc
     3781 tgctctcaca ttatactgcg cagtcgcttc cggctccttt gctaaaaata ttcataagga
     3841 actctttgag aagctatgag ccttcgtttg agacgtttta agacagtctt agtataaatc
     3901 ccttatcttg ttcttaaagc gccttacagg cggtcagggc aagccctaac aaccctaaag
     3961 ttgtctgaat gccctctaaa attcgattta agcactctta aacctattct tatatattta
     4021 tatacttaga cgtttcaaac gtcttaaaac gcaaattaga gcttgataaa gatatttgct
     4081 cgtgtgccga cttttttaaa agtctaggca cacgccatga caaagctgaa ataaactgct
     4141 tcagctttgt catggcggat tcgctcactt gaaaaagtgt tcatttcgct cgattattag
     4201 catatatttt ttaacttttt ttgctagcca aattttgcat tagttcgctc ataaatccca
     4261 ccctttcagt acgtcctacg gacgtatcgt tcgtaatgtg aaagtacctt taaaggtact
     4321 ttctacaaaa ctcactaaag ggtttggcaa gctctatatt tgctagccaa atacctacgt
     4381 atttggtgca aataaccgct tgtcaaaggg gcgcaagctc ccccttgaat cccccctcaa
     4441 aacccacgct ccacaataca aaaaaggcta gcaaatgcta gccacttttt gtaaagtttc
     4501 gcttgtttca ccttcggtga aattgttgct ttgcaacgat caggtagagc tacatttttt
     4561 ttcgttgttc aaatattctt acgccattta ctattaaaat cgtaggtatt ccaaagtaaa
     4621 gaaaaaattg attagcaggt aatacaaaat ataaaataat accagcaata attaccaaac
     4681 ttatagtaag ttttgttaat ttcatgaagt atgccacctt atcttatata gatatcaaat
     4741 agattaatat gccgattgta ttataaaatc catgagcaac tatggaatac catatatttt
     4801 ttgtttgtat ataaacaaaa cttaaaataa taccaataaa gaaaatactt aggcctcccc
     4861 catgaacaat agaaaacaga aaagaagaaa ttagtattga aatatattgt tgttttttgt
     4921 ttgcttgagg atcaatcata caaaatcgaa aaattccttc ttctaaaaaa gctccataag
     4981 tagcagcatt taaaaagaat aaaaggagag aaccatttac ttcattagga tttatacctt
     5041 ctgaaaaaga tgtatttaga atattgatta ggaataaaac agagaatg
//
LOCUS       DADLIO010000120         5049 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.126, whole genome shotgun sequence.
ACCESSION   DADLIO010000120 DADLIO010000000
VERSION     DADLIO010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5049
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.126"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(136..1098)
                     /locus_tag="JOX41_002727"
     CDS             complement(136..1098)
                     /locus_tag="JOX41_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAY6450408.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1100..2539)
                     /locus_tag="JOX41_002728"
     CDS             complement(1100..2539)
                     /locus_tag="JOX41_002728"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HAY6450409.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2724..4670
                     /locus_tag="JOX41_002729"
     CDS             2724..4670
                     /locus_tag="JOX41_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HAY6450410.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKGTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            4934..>5049
                     /locus_tag="JOX41_002730"
     CDS             4934..>5049
                     /locus_tag="JOX41_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010051189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAY6450411.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEET"
BASE COUNT         1634 a          845 c          829 g         1741 t
ORIGIN      
        1 tttctccact ccaaaaaagt ctaacttttg ggggtcacta caagttgaca actccttttt
       61 gtttacaaat caattggata tctacaaatt gtattttcta acgaatttta tagacattaa
      121 aaaattaatt taacgttaaa tacttcctcc agaaagtatt gagattggta aaatataatc
      181 cttatttgtc ttttcgcctt taattttttt cagaagaata tcaacaataa gacttgcaat
      241 ttcatcaatt ggttgtctta ttgttgtcaa ttgtgggaaa aatttctcaa taaaagaggt
      301 accatcgtat ccaataattt ttaaatcttc tgggatatta agtttaagtt gatgagcaat
      361 tttcatagtg agaatggctg ttaaatcatc agaaacaaaa ataccatctg gtttgtgatt
      421 tataatagtt gactttattt ccatttcacg acggatagta gacagattat taggaatttt
      481 gaaaattttt ccatttggat tttgaaaaga aaaacctagt gcacgtaatt ctgtgggaga
      541 atccgtgtta tcatttcctg taatcataat ggtattttga caaccatttt tttgtaaagt
      601 cttagctgca agttttcccc cttcaaagtt atctgaagaa acaatggaaa cattaggagc
      661 taaatttcta tcaaaagcaa caataggtgc tctcacacgc tcataatcag caattccaag
      721 attatggctt gatgagatta tgccatcaac ttggttggct tcaagcattt caatgtattc
      781 tctctcttta gcaggatcat tttgactatt gcaaataatc gttttatatc catgtttaaa
      841 taactctatt tcgagatact caatgagttc agagtaaaag atattactaa tattaggaaa
      901 aataagacca ataagctgag gtgactttcc ttgaagtcca cgtgctaaat tatttggttt
      961 ataaccaaga gttttcatag cttcatgaac tttttgtttt gttttttctg ataaatatcc
     1021 cttattatta atgacgcgtg aaacggttgt tgggctaact ccagctaatt cagcgacatc
     1081 agttaatttt gctaccattt taatatttta attcaaagta ttttccagta ggttcgcctg
     1141 atttgatttg aataccattt tggtgatttt cagggaatac acgactagta aacacttttt
     1201 ctcctttatt aataaaaatc tcaatgattg agttatctac aaaaatgtta gcagttgttt
     1261 ctttagtatc aattgagcat tcacgaatcg taccaaagtc agtggcatat tgaatgcctg
     1321 ctttgctgcg atctaaaata atttttcctt ctttggtatc tacaatcaag ctaagtccat
     1381 ttcctttact atcagagaaa agaagtaact ccgatttctg atttggagga aaagttagtt
     1441 caagctcata agtattattt gtttctgctt ttgctgtaaa ttgttcagaa ctagcacgta
     1501 atgatgtaat agcttctact ggatattggt aaagtttacc atcttttatt gaaagttctt
     1561 ttacaagact cattgctccc tgataatcat acttatcagt tggataatcg atatcaggta
     1621 gtccaatcca actgacaatc agagcacgac catcaggagt attgaatcct tgagtcgcat
     1681 acgcttcaaa tccataatca agattttgaa tttctgaagc gcccacaagt tttacttttt
     1741 ctatgtcaag cgattgacag atcttaaaag tattcggata gatattccca taatttagct
     1801 cagatttatc caacccttga ggacaataaa tgagaacagg ttttttgtct acaaatacta
     1861 gatttggaca ctcaatcatg tattctgaac cagtgccgcc aaaatcaagg ttgccaactt
     1921 cctcccatgt ttccacgtta ttgtcatccg ctttgtaaag tttgataaag cctgattttt
     1981 ctaaattttg tgctccaaca atcgcataca attgtccttc ataattaaac atttgtggat
     2041 cacgaaaatg atcagttaca tcagcaggtt tatgaataag aacattctca cctttcgtaa
     2101 tgttgtagtc tttatccatc catgctccga tttgaagtgt atcacgttcc caattttcat
     2161 ttcgaacgtt tcctgtatag agtaagaata gattcccctc tatttcatat gcagaaccgg
     2221 aataagcgcc gtggctatct cgttttgtgt ctggaagaag ttctgctcct gttacatgaa
     2281 aatgaactaa atcatctgat tcattgtgta cccattcttt caacccatga gcagctccaa
     2341 atggccaatt ttgataaaaa agcgtatatt ttccgttaaa aaaagaaaaa ccattaggat
     2401 cgtttaacaa tcctgtttta ggttcgatat gatagctagc acgccaaggt gatcgtttta
     2461 cattatcctt aattttatcc atctcatctt tagtccaatc agaataagca cgatatcgta
     2521 tttctcgagg taagttcata ttttactcct tcaatttatc tttttacaac tagtatggta
     2581 aacgttttcc gttgaaaaat caatcatttc atttaaaaaa ataaactata tgacaaacgt
     2641 ttgacatatt tttaagatat gctaaaataa atttgcattt cagtgaaccg ttttcacgta
     2701 aaaataaaaa aggagtgatt cgaatgaatt acagtaaagt agcttccgac gtaatacaag
     2761 cggtcggaaa agataacctt attgcagctg cacactgcgc tacacgtctt cgtctcgtac
     2821 taaaagatga cacgaaagtg aatcaaaaag ctttagacga aaatccagat gtgaaaggca
     2881 catttaaaat tgatggacaa tatcaagtga ttatcggtgc aggtgatgtt aatttcgttt
     2941 atgacgaact tatcaaaaaa actggacttt cggaaatttc aacagatgat ttaaaacaaa
     3001 ttgctagtaa agataaaaaa ttcaacccca ttatggcatt aattaaatta ttatcagata
     3061 tttttgttcc aattatacct gcccttgttg caggtggttt attaatggca ttacaaaact
     3121 ttttaacagc tgctggactt tttggaccaa aatcaattga agaaatgtat cctgcgattg
     3181 aaggtatttc ctcaatgatc caactgatgt ccgctgcacc attcatgttc ttaccaattt
     3241 tagtaggtat ttcagctgct aaacgttttg gagcaaacca atttcttggt gctgcaattg
     3301 gtatgatcat gacaacacca gatcttggtg gctcaactga atattggaat atttttggtt
     3361 atcatgtttc acaaacaaac tatgcttatc aagttattcc agttttagca gctgtttgga
     3421 tattatctat attagaaaaa ttctttcata aaaaattgcc atcatctatt gactttacat
     3481 tcacgccatt attatcagta atgattactg gatttttgac tttcacagtt attggccctg
     3541 taatgttatt gttgtctaat ggaattacag acattattgt ttggctatat aacactactg
     3601 gatttattgg aatgggtatt tttggaggaa catattcact tatagtcatg actggtttac
     3661 atcaatcatt tccagctatt gaaactcaat tactttcagc gtggacaaat ggtatcggac
     3721 atggagactt tatctttgta gttgcatcta tggcaaacgt tgctcaaggt gctgcaacat
     3781 ttgccatttg gttcttaact aaaaattcta agacaaaaag tcttgcttcc tctgcgggtg
     3841 tctcagcact tcttggaatt acagagcctg ccttgttcgg agttaactta aaataccgct
     3901 ttccattctt ttgtgcttta attggttcag gaattgctac agcagtagca ggattactta
     3961 aagtagttgc tgtttcactt ggttcagcag gtttcttggg atttctttca attaatgcaa
     4021 catctattcc attttacgta ttgtgtgaat tgattagctt tgtagttgct tttgcaatta
     4081 cttacttcta cggtaaaaca aaagctgctg gtatctttaa agcagaagaa attgctgaac
     4141 aaacaccagt taattcttca aaagtagcaa caacagatcc aatatctact gatgttgaat
     4201 caacacaaac aaaagtttca tcagaaacaa ttgttagtcc catttctggt aaagtgatta
     4261 gtctttcttc agtaaatgat ccagtctttt catcagaagc tatgggaaaa gggattgcca
     4321 ttaaaccaaa tggaaacacg gtccattctc cagtagatgg tactattcaa ctcacgtttg
     4381 aaactggaca tgcttatggt attaaatcaa ataatggtgc tgaagttcta attcatattg
     4441 gtattgatac tgtatcaatg ggaggaaaag gatttacaca aaaagttact actaatcaaa
     4501 aagttagaaa aggcgatatt cttggagcat ttgaccgttc aatgattgag aaagaaggtc
     4561 ttgatgatac aacaatgatt attgtgacca atacttcgga ttattcagaa gtaaatatag
     4621 tagctgaaaa tacagtcact gagggtactg atttacttga aatcaaataa atatatttcc
     4681 ctgagtaaag atggaatttt ctttccaaaa tcaaataata tagattaatc aaatatttga
     4741 gaataacatt ttatttaatc ttttcatata tcaattgtat gaaaaattat tagaatttta
     4801 aaaaatgata aaaattcaaa aagaaaaaat agtagttatt tacttgtcat gttactaaat
     4861 aaaaaaataa tttaaatatg atatatagtc atttatttag tgatttcatt ctaaaataaa
     4921 gggagaaatg tctatgctat acggtgcaat tgaagcaggc ggcacaaaat ttgtgtgtgc
     4981 cattggcgat gaagaaatga cgatcaagga aagagtgagc tttccgacaa cgacacctga
     5041 ggaaacaat
//
LOCUS       DADLIO010000121         4931 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.127, whole genome shotgun sequence.
ACCESSION   DADLIO010000121 DADLIO010000000
VERSION     DADLIO010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4931
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.127"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            83..970
                     /locus_tag="JOX41_002731"
     CDS             83..970
                     /locus_tag="JOX41_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAY6450412.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1110..2036
                     /gene="cysK"
                     /locus_tag="JOX41_002732"
     CDS             1110..2036
                     /gene="cysK"
                     /locus_tag="JOX41_002732"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HAY6450413.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2272..2718
                     /locus_tag="JOX41_002733"
     CDS             2272..2718
                     /locus_tag="JOX41_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAY6450414.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2991..4343
                     /locus_tag="JOX41_002734"
     CDS             2991..4343
                     /locus_tag="JOX41_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase"
                     /protein_id="HAY6450415.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4514..4801
                     /locus_tag="JOX41_002735"
     CDS             4514..4801
                     /locus_tag="JOX41_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450416.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1693 a          813 c         1030 g         1395 t
ORIGIN      
        1 ttaaaagtat aatttaatta attaagtttg ttttaagaag agaacttttt attaagtttt
       61 tttattttga ggaggaattt gaatgcaaga gctgaagacc cgcagtgccc ggcaccatag
      121 acctaaaaga aaaatggtga tcaataaaaa agcgattgct cctttaattg gaacgagtct
      181 tttagttggg ccgatgatgg ttacagcggt accgcaacat gttcatgcag atgaacaagg
      241 atctcaaaca gtcgctgatc ctcaagcgtt tatcgatcaa atcggctggt ctgcgtcaga
      301 agttgctgca agtaatgact tgtatgcttc agtcatgatc gctcaagcgt tgttggaaag
      361 tgcatatggc acttccggat tagctagtgc gccaaattat aatctattcg gtgtgaaagg
      421 aagctataac ggacaggtcg tttatatggc aaccaaagaa tatgtaaacg gacaatgggt
      481 aacgatgaat gagccattcc gaaaatattc ttcttattgg gaatccttcc aagaccatgc
      541 gaatgttctt cgttcaacca gtttttccac gggcgattat cattatgctg gcgtgtggaa
      601 aagcaataca acaagttttt atgatgcaac agcgtacttg acaggtcgtt atgctaccga
      661 tccaaattat ggggccaaat tgaactcatt gattaatact tataatttaa cccgttttga
      721 tacgccatca acaggttcgg ctacaacaac cacaagtaca acaacaacga ctactacgac
      781 gacttcaacg tcatcatctt caacaacaga tgtaaataca aataatggtc agacatatac
      841 agtcgtgtca ggtgatacgc tatgggatat tgcacaaaaa tttggcatgt ctgttgatga
      901 tctaatggcg aaaaatggca tgtctatgtc cagttattct ttattagttg gtcaagaact
      961 aaacgtttga tttagataaa aaggcaaaga aattaccata tatggtatat ctttgtcttt
     1021 tttttgctag tcaaagacga atcactcgcc ataaatgaac agattgtatt atgataagta
     1081 agaagagcaa agacaaggag gaattgaaga tgacagctat ctataactca gtcaccgaat
     1141 tgattggcaa aacgccaatc gtcaaattaa ataaaatcgt accagaagat tcagcagatg
     1201 tttttgtaaa gcttgagttt tttaatccag gaggaagtgt aaaagatcgt attgctttaa
     1261 gtatgataga aaaagcagaa cacgatggtc tactgaaacc aggtgatact atcattgaac
     1321 ctacttctgg aaatacagga atcggattgt cgatggtagg agttgcaaaa ggatataaag
     1381 taatcatcgt gatgcctgag acgatgagta tcgaaagacg tttattgatg aaagggtacg
     1441 gcgcagagtt gattttgact cctggtgcgg atggtatttc tggatcaatc agagaagcag
     1501 aacgtttggc aaaagaaaac ggctactttt taccattaca atttgaaaat gaagcaaatc
     1561 ctcttgtgca tgagaagacg actggtcctg agatacatca agcatttgga gtaaatggct
     1621 tggacgcgtt tgttgcaggt atcggtacag gaggaacgat cactggcgct ggccgagaat
     1681 taaaacgtgt gtatccgaaa atcgaattaa tcggggtaga accagcagaa tctgctattt
     1741 tagaagggaa agaagcggga cctcacaaaa tccaaggaat cggtacaggt tttgttccta
     1801 aaacactgga tacttctgtg tatgataaag tcctttctat tagtggagac gaagcgatgg
     1861 aaacagctag agaagttggg cgaaaagaag ggattttagt aggcatctca tctggcgctg
     1921 caattgctgc cgcgctaaaa gtcgcaaaag aattaggaaa aggcaagaag gtattagctg
     1981 tggttcccga caatggtgaa cgttatttat ctacagccct ttaccaagag atataaggca
     2041 cttggttttt ctccagatag gtttatgtaa aaaactttta aagatgaaaa gaacacacaa
     2101 aaatttatga tgagaaaaat tatttgaata gagacgtaga atagtgaacg cgactgtttt
     2161 acgtcttttt tcattaaaat acaataaaat tgaattttct tttcatgtta agtggatttt
     2221 aaaatgtaaa aatagtatga taagacgaga ataacaacgt ggggtgttta catggaaaat
     2281 aagttagtcg aagaggttat cgaaaagtta aaaaaagaga acattcgaat cacacctcaa
     2341 cggtacgcgg ttttagaata tttgattgaa catcattccc atccaacggc tgatgagatt
     2401 tataaagcac ttgaacatcg gtttccaaat atgagtgttg cgactgttta caataacctt
     2461 cgcttattta cttcgattgg atttgttcaa gaaatgaagt acggcgatgc ttctagccga
     2521 tttgatttca gttcaaagcg tcattatcat gtaatttgtg aaaactgcgg taagattgtt
     2581 gattttcatt acccagggct tgaagatata gaaatggctg caagcagact gactgatttt
     2641 gagattaatg aacatcggtt ggaattgtat ggactctgtc cggattgtaa agagtcagca
     2701 aaaaaggcgc aaatgtaaaa acagtttcta caagtgttat acctaaaaaa agctagctgt
     2761 gtaaaaaaaa cgctagcttt tttatttttt tgtcttttat tcacaatctt agatataaaa
     2821 gtgaatatta ttaaaataag aatcttgtag atattgggtt cttatgcttg aaaaggaatg
     2881 aaactacaaa caaacctttg tgaattcaca agcattaaac tgttgtatcc gttttatttc
     2941 tgttatagta gttttgtcga aggacaaaat gttaatcgga gggaccataa atgaaagtag
     3001 tagtaattgg ctgtactcat gcaggtactg cagctgtaaa aagtatttta aaaaatcatc
     3061 cagaagcaga agtgacagta tatgaaagaa atgacaatat ttctttctta tcttgcggta
     3121 tcgcacttta tgtcggcgga gtagtaaagg acccagcagg cttgttctac tcaaatcctg
     3181 aagaattatc ttcattagga gcaacagtta aaatggaaca cgatgtaaca gacgtcgata
     3241 cagaaaataa aacagtaacg gcaaaagatc tgaaaacagg agaaacagaa acggtttctt
     3301 atgataaatt agtgatgaca actggttcat ggcctattat cccaccgatt agtggaatcg
     3361 atgcgaaaaa tgtactccta tgcaaaaact acaatcaagc aaatgaaatt attgcacaag
     3421 cgaaagaagc aaaacgtgta gtaattgttg gtggtggata tatcggtatt gaattagtag
     3481 aagcttttgt cgaatctgga aaacaagtga cattgattga tggattagat cgcatcttga
     3541 ataaatatct agataaacca ttcacagata tcttagaaaa agaattgaca gaccgcggtg
     3601 ttactcttgc gctaggcgaa aatgttactg aatttatcac agatgaagaa ggaaaagtga
     3661 aacaagtagc tacaccaaca gatacatttg atacagatat ggtcatttta tgtgtgggct
     3721 tccgtccaaa tacaaaactg atcgaaggaa aagtagatac actgccaaac ggggcaatca
     3781 aagtgaatga atacatgcag acaagtaatc cagacatttt tgcagctgga gactctgcag
     3841 tagtcaacta caatccaagt ggcacgcaaa actatattcc tttggcaaca aatgccgttc
     3901 gtcaaggttt gcttgtggga aataacttga cagatcataa aatggcgtat cgtggtactc
     3961 aaggaacttc aggactttac ctatttggct ggacgatcgg ttcgacaggt gtgaccaaag
     4021 aaagcgcaac tttgaacgat ctagaagtcc aagcgactgt atttgaagat aattatcgtc
     4081 cagagttcat gccaactact gaaaaagtaa tgatggagct agtctatgaa aaaggaacga
     4141 atcgtatcgt aggtgctcag ttcatgtcca aatacgacat tacacaatca gcaaatacca
     4201 tgtctttagc tgttcaaaat aaaatgactg tagaagatct cgcactttca gatttcttct
     4261 tccaaccaca ttttgaccgc ccatggaatt acttgaacct acttgcacaa gcagcgctag
     4321 gcgaaatcga aactgcacaa taaagaaaaa gggttgtgac acaattttgt cacgaccctc
     4381 tgtctttttt tgtgaaaagt acaattagtt gtctttcttc gaattttttg tcacaataag
     4441 cagcaaagat aaagctgtta cataaaagaa caagcagctt tatttgattt tgaaaagaaa
     4501 ggtgagaaag aagatgaata aagaatattt tgtccaacaa gatgcatttt tagaagatta
     4561 taaaagtgct tcgaagaaat taacgatcaa tattgatgag ttggcagatc aagtactctc
     4621 tcagttgaat gaaacgcaag aggaatatta cacgatgcca gcaaatgacg ccaaagataa
     4681 tgtttctcat cgttttcctt tcagtagacg catctactca gatgaaaatg acggcacatt
     4741 gaatacagag tacacatatg aaggtcagcc atatgtgcta gaaactgatg atgatcttta
     4801 aagacagttt ttgaaaaggc cgctcatcct taagtgatga caaaaaatca tcacaattac
     4861 cgatgactgt ctctttacta tcttttaatc agaaaaaggg gttatgacaa gctttgtcaa
     4921 cccctttttt t
//
LOCUS       DADLIO010000122         4892 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.128, whole genome shotgun sequence.
ACCESSION   DADLIO010000122 DADLIO010000000
VERSION     DADLIO010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4892
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.128"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            166..966
                     /locus_tag="JOX41_002736"
     CDS             166..966
                     /locus_tag="JOX41_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAY6450417.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            985..2853
                     /locus_tag="JOX41_002737"
     CDS             985..2853
                     /locus_tag="JOX41_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAY6450418.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            2846..3337
                     /locus_tag="JOX41_002738"
     CDS             2846..3337
                     /locus_tag="JOX41_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HAY6450419.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            3325..3879
                     /gene="srlA"
                     /locus_tag="JOX41_002739"
     CDS             3325..3879
                     /gene="srlA"
                     /locus_tag="JOX41_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174078.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HAY6450420.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            3897..4892
                     /locus_tag="JOX41_002740"
     CDS             3897..4892
                     /locus_tag="JOX41_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HAY6450421.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         1702 a          765 c         1030 g         1395 t
ORIGIN      
        1 tatataacgc tcaggaattt tagcaatcta tgcaaaaaga tgaaaatttt ttttgctctt
       61 ccattagtac acatttttta gctgaagctg taaatttcat gtcttaattt tttttagtga
      121 gcttttatac tggatttgta agaaaaaaga aggagaggat cacatatgtc ggattggttg
      181 gatattgcag gaaaagtagt aattgtaact ggaggttcct caggaattgg aagaagtatc
      241 gtcgaaaatt tgttgaagca gaatgcacaa gtagcgaatt ttgatgtaac tgaatgccgt
      301 atacagcatg aaaacctact atctttaaaa gtcgatgtgt cttctaaaac ggacatagaa
      361 gaagggatat ataaagtaat gaaacatttc aagacgatcg atggtctagt caataatgca
      421 ggaataaata ttccttctct tctaatagat agaaatcatc caaaaagcaa gtatgaatta
      481 tcagaacaag tttttgataa gatgatcgct gtcaatcaaa aaagtgtata tttgatgagc
      541 caagcagttg gaagaatctt ggtgcaaaag ggatcaggag tgatcgtgaa tctttcttct
      601 gaatcaggat tggaaggatc agaaggacag agctgttatg ctgctacaaa agcagcgatg
      661 aacagtttta ctcgttcttg ggcaaaagag ttaggaaaga ggaatgttcg tgtggtaggt
      721 gttgcaccag ggatactgga agaaaccggt ttgagaacac aagaatatga agaagctctt
      781 tcttatacga gaggtataag cgtcgaacag ctgagaaacg gttacagtcg aacaagtacg
      841 atccctctag gaaggagtgg taagctgcaa gaagtggcgg atctagtctg ctattatctt
      901 tcagaaagat caagttatat cactggagtc acgactaata tttcaggagg taaaacaaga
      961 ggataaagga taggggggac gcacgtgacg ctagtaaaca gatggtacca attattgaaa
     1021 ttactagtca ctcacaagaa agtttcaatc caggaagtgc aaaaagaaat caaaaccagt
     1081 aatcaaacca taaaaaaaga tattggggag ttgaatgaag aaattgccgg tattgcaaaa
     1141 atcatccaaa aaaacaaaca ttttgaactt gaaatttatg attttgattt ttttgatgag
     1201 atcatgcaag gaaaattgaa aacagccagt gatttcaatt cggcatccaa aagaatcgct
     1261 tatttactaa ataggctgat cgaaacagag gatttcttac gtatggatga tttgtctgaa
     1321 gaagtcggtg tcagcagagg aacagtggtc aaggatctaa agacattaaa agagatgatc
     1381 aatgattttg atgtaaagat tacaggcaca ccaaataaag gactaagaat aataggagat
     1441 gagctagaat tacgactact tttattttat tttgtttctc cctacttttc agagacgaaa
     1501 acagaacagt ttctagaaga aaaacaagca atcaaacatt ttcagaagaa gacgaatgct
     1561 agtaaacaag aaatcaccct tttaacgaaa gttatcggta tttctttgaa tagaatctct
     1621 agtaactatc tgttgaagaa gcccatcaat cgttacagtg ggtgttttga atatatccaa
     1681 gaattcaatg aactgatcaa tcagttggaa gaaatctatg aactaacttt gagccaatat
     1741 gaaaaagatt ttatcagttt tcctttgaac atcatcaaca caagtataac gatgataagg
     1801 aaagctaact ctgatttgcg cttatatttc gaccccatga tgatgcgtat tcgacgatta
     1861 gatctcattg atctggatga gtccttctta tatcaagaga tgaaacagca cctctcttta
     1921 ttgataaatc gggtaatttt tcgttatcga ttgactgatt tattttatgg tgagatagaa
     1981 aaaaagtatc ctttttctta ccaaatcgct agcgaatgca tacaagcatt agaagctatc
     2041 ttgcaacata agatctctaa agtagagatc agctacctaa cgttgtattt ggagttagca
     2101 tttcgatatc aaaaagagca tttttcctct aaaaaagtag ccattgttca tacgacagga
     2161 aaaggaacag cattaatgat ccaaagacaa atcaaaagga tattggggag ggatatacaa
     2221 ataacacatg tttcagaaga acaatatgaa aaagtagatc taaacaaata tttcgctgtt
     2281 tttacaacga ttccgttaaa aaatgtaaat gaagagacac cggtgatcca tttgactaat
     2341 ctttttgatg actcttggtt aagggcacaa tggcaaaaag caaaaaaaaa gcgattagcc
     2401 gggtttcatt ctactgtttt tttctatcaa atatggaaag aaaaaaagac gtatcaagaa
     2461 tatttaaaca aattagtcgc tcctttgatc agaggctatt atgtggatga agaatttgaa
     2521 aaaaggatct tgaaaagaga atatcagcaa agcacatttg ttaacaaaga atttgctttt
     2581 cctcacacaa ccaaccagct atctcaacac attgttttat cagtagggct aataactgat
     2641 caaggtttag cagaaacagg aggaaatgga gttatttttt tatttgccat acctgaagaa
     2701 atgacggctg aagttgagaa tgaattattt gagctatacg atatcctatt tgaactcata
     2761 aaaatgggaa tagatgagtt tattgaatta gcaccgacac aagaatcatt tttaaaacta
     2821 atcaaaagta aaggagagag acttcatgaa tgatatgtat ctattcatag ttttcgcagc
     2881 ttcagcttat gtgctgcaag cagttatcag ttggaagcaa ctaaagcatt tcaatcaaac
     2941 atatagcgaa ctgcgaagaa aaggaaaagt agcgattggt aaacgacctg ggaaaatccg
     3001 ttcaggcacg attgttatgc tagctataga cgatcatgat caagttttag aagtcagaaa
     3061 aatgcaaggg gttacatctt tggcaaaatt tcattcatta cctgtctatg cgggtgaaga
     3121 tatccattac atcgatcgtt accatccctc agttcgagcg gaagatcgtt tgacacaagc
     3181 agctttagaa aatgccagag aagtatactt acgaatagag gcaggaaatg aaaaaagtga
     3241 acaaccttca ttgcctttta ttgctatgct caataatttt cggatatgga aaagtacgat
     3301 caaagaaaaa aggagtgaca aacgatggat atcataacaa aatttgctga gggatttatg
     3361 aggctgttcc aaacaggtgc agaaacattc ataagctgga tgacaggaat cgtaccagtt
     3421 gtcttgatgc tgatggttgc aatgaatacg ctgattgctt ttttaggtga agaccgagta
     3481 acgaaagtag ccaaattatc agcgaaaaat ccgcttactc gttaccttgt gttaccgttc
     3541 ttatctgctt ttatgttggg aaatcctatg tcatttacaa tggctcgttt ccttccagaa
     3601 tactacaaac caagctatta tgctgctcaa gctcaatttt gtcatacgag caatggtgta
     3661 ttcccccata ttaatcctgg agaattgttt gtatggatgg ggattgctca agggatcgaa
     3721 accttagggc taaattcgat ggagctggct atccgatact tgcttgtggg actgctgatg
     3781 aactttattg gtggttggat aactgatttt actactggat ttgtatgcag acagcaagga
     3841 atcgttctta gcaaaaaagt agagctttca gttgattaga gaaaggagag ttttaaatgt
     3901 atggtgatat taagatcgta agaggaaacg gcgggtatgg aggtcctttg attattaggc
     3961 cgacaaaaga taaacacaag ttcatctatg tcacaggtgg aggtgagagg ccaatgatcg
     4021 tagataaaat agaagaactg acaggtatgg agtctatcaa tgggttcaaa acatcaatac
     4081 ctgatagtga aatcgcgctt gcaatcgttg actgtggagg gactcttaga tgtggaattt
     4141 atcctaaaaa agggatacca accatcaata tcgtttccac aggaaaaagt ggcccattag
     4201 cacaatatat cactgaagat atttatgttt cagcagtagg gttagaacaa atacagccac
     4261 taatggaaac tgatgataac aaagaaacag taaatactgc atctccagat aaaaagtaca
     4321 aatatgatac ttctaaaaag ataaccgagc aaaaagcaga gcagcaaaac tggatagcaa
     4381 aaattggaat gggcgcggga aaagtagttg ctacattcaa tcaatcagca agagaagcag
     4441 tagatacgat gatccggaca gtgatccctt ttatggcttt cgtttccctt ttgattggtg
     4501 tgatacaagg ttctgggatc ggtaatgtat ttgctaacat tatggcacct ttagcaggaa
     4561 atgcagttgg attaacaatc attggcttta tttgttcact gccattttta tctcctttgc
     4621 ttggtccagg ggcagttatt agccaagtga ttggaacatt gatcggtgta gagattggga
     4681 aaggaaatat tcctccccaa ttagcattac cggcactatt tgctatcaat actcaaaatg
     4741 catgtgattt tattccagtc ggtctaggtt tggaagaagc aaaagctgag acagtagaag
     4801 taggtgtacc atcagttctt tattcaagat ttcttaacgg catcccacga gttatcattg
     4861 cttgggtagc aagttttgga ttatatagct ga
//
LOCUS       DADLIO010000123         4841 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.129, whole genome shotgun sequence.
ACCESSION   DADLIO010000123 DADLIO010000000
VERSION     DADLIO010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4841)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4841)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4841
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.129"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(<1..1140)
                     /locus_tag="JOX41_002741"
     CDS             complement(<1..1140)
                     /locus_tag="JOX41_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAY6450422.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDIEGKVLSMYARGMSQCDIAATVEDIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKVRGVEDVFFISMDGVSGLKEGAKAIFPSVIVQRCIVHLVRNALRYLPSK
                     DYKEVCRDMKKFYSASSLNAAHAAFDSFQNRWSHYSGAVDVCKRNFSHVEQLFDYGSA
                     IRKIMYTTNAVESIHSSFRKVTKKGVFSNENAQTVDKVHFMDDVYS"
     gene            complement(1270..2646)
                     /locus_tag="JOX41_002742"
     CDS             complement(1270..2646)
                     /locus_tag="JOX41_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAY6450423.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(2646..3302)
                     /locus_tag="JOX41_002743"
     CDS             complement(2646..3302)
                     /locus_tag="JOX41_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAY6450424.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            complement(3312..4589)
                     /locus_tag="JOX41_002744"
     CDS             complement(3312..4589)
                     /locus_tag="JOX41_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAY6450425.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            complement(4608..4763)
                     /locus_tag="JOX41_002745"
                     /pseudo
     CDS             complement(4608..4763)
                     /locus_tag="JOX41_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
BASE COUNT         1523 a          878 c          590 g         1850 t
ORIGIN      
        1 actgtagaca tcatccataa aatggacttt gtctacagtc tgcgcattct cattagagaa
       61 cactcccttt tttgtgactt ttctgaagct agagtgaata ctttcaactg cattagtagt
      121 gtacatgatt tttctaatgg cgctgccata atcaaagagt tgttcaacat gagaaaagtt
      181 tcgtttgcat acatctactg caccagaata atgagaccac cgattttgaa aactgtcgaa
      241 ggcagcgtgt gcagcgttta aagaagaagc actgtagaat tttttcatgt ctcgacagac
      301 ttccttataa tccttacttg ggaggtatcg taacgcattt cgaacaagat gaacaataca
      361 gcgctgcaca atgacagaag gaaaaattgc ttttgcgcct tctttgagac cggaaacacc
      421 gtccatcgaa atgaaaaaaa catcttctac accacgtact ttcagttcat caaatacttg
      481 catccagcga tttttagatt ctgtttgatt gagccatagg cctaaaatct ccttgtttcc
      541 tttaagatca tagccaagaa tggtgtacac agcatattct ttagcttcat agttttcgcg
      601 taaagtgacg tacatacaat caacgaatag aaatgcataa cacttggcta atggccgagc
      661 ttgccattct tccaattcag gaaggacggc atccgtgata tcagaaatca tttcgtggga
      721 aatatcaaag ccgtaaatat cttcaacggt tgcggcgata tcgcattgac tcattcctcg
      781 tgcatacatg gaaagaacct taccttcgat gtcggagaca tctcgttttc tattaggaat
      841 caactcaggt tcaaaagaag cctcccggtc tctgggaaca tcaatgttta ctttaccaaa
      901 gctcgtttta agcgtcttat tgccataacc gtttcgtcga ttgtcatgtt tctttggctc
      961 tttagaatgg gcgtcatacc ctaaatggtt attcaattct ccttgaagca ttttttcaaa
     1021 taagggacca aacacatctt ttaaaacatc ttgcatatcc tctacagatt cgggttgata
     1081 agtattcaaa atggattcag ctaacttctc agcatcagga tttcttttct ttctagccat
     1141 cgtgtaatca cctcttgatc ttattttaga aaaataaaaa ccgtgaagca accacccgcc
     1201 taggattgat ggttacttac acggtttata ttacactctc atttttggtg ctaaaaagca
     1261 ccgaaaattt taattattgt caattaataa ttcttttgga ttccttctta atatattgaa
     1321 tgaagaaata atcaatgata caagaagtac taaactcata aatataacta cataaatcat
     1381 gaatttaggt aatacattga tatctaaact tgataatgtc ttgttaaatc cttcagcttc
     1441 tgccccacca cctaattggc tagatgcaga ttgtttagct atttgtttag ctatatcacc
     1501 agtaacctta ttcaatatat tattcccaag cttgtcagct gtatattgag ctaagaaata
     1561 ggaaccaacg aatgcgggga ttgatataaa taccatctca attaggaatt gaccaaaaat
     1621 ttctaatttt gatataccta atgatagtaa tactgctatt tctttctttc tagcattcat
     1681 ccataagaat aataataatg aaactacaac tcctgcaaat attaatgagc caaaaaataa
     1741 tttatttgaa attgagtaaa tacctgatat agattgttgt aatgcagggt aatttgatga
     1801 acttttaatc aaattatatt ctctccaatt tatatctaat ttcccaagat cttttattac
     1861 actatcaaga ttcttatcac cttttacaaa gaatgttgca tcttggtata cagctgtatc
     1921 ttcggtatta ccataaactt tagcagctgt atgaatatca gtgattaatg tattttcgta
     1981 tagttcttgt gctgcactta ctccaccgct attatgccca tcgaatagac ctttaatttc
     2041 tacttctact gtttcatctg cacctttctc attatcagca tcaaataaat tagattttat
     2101 ttttatctta tctccaactt taaggttatt tttttcagct aaatctttat gcattaagat
     2161 tttattttta tcttcatttt ctaaatgctt tccttctact aatttatatg cttctgatac
     2221 aaattttgtt tcttttgttg agtcgttaac cccagttaac ataactgttc ttttaaaatt
     2281 ctttgctctt tcaggtgatt gattcgcaag agtctcttga gtttcaataa tatcataatc
     2341 aactaaatct gcaacactgt ttattctttt tacataggag tctatactat ctgtttgaga
     2401 tatcttttta atatcttcac cttttacatt tcccccacct ctaggtgttc ctggatttac
     2461 ttgtctattt atctccatag aaaaactatt tgttatatta gcaaatgttt cttttgaagc
     2521 tctgtccgta gcatctttaa tagataaact aatgagactt aaagttgaca tagataaaat
     2581 aactaatatg ataattaatg attttaaact ttttctagtt acataagcaa atgcattttt
     2641 tatcattatt caacctccaa attcatttta tttacttttt tcaacttttt accacttagt
     2701 tctaaaatga tatccgcaga atctgctact tccttactat gtgttacaac tattacacat
     2761 ttatttctat ctttagctaa tgtctttaat atattaatta tttctccagc agtaacactg
     2821 tctagattac cagtaggctc atcagctagt attattggag catctgatac caatgctcta
     2881 gcaatagcta ctctttgttg ctgtccacca gataatttca taacatttct ttttatttgt
     2941 tttttatcta aacctagttc aaacaagata ctttcatctg ctgatttatt tactaatcta
     3001 atattttcaa ttggtgataa ataatctatt aaattatagt tttgaaatac taaagatata
     3061 ttattttttc tatgattact atatccttta ttttgtatat cttcattctt aaacaatatt
     3121 tttcctgttt gaggtttatc aagtccagca agtaaggaaa gaagtgtaga ttttcctgtt
     3181 cctgactttc ctactatcgc ataaaacttc ccaagttcaa atttttgatt tactcctgac
     3241 aaaacttttt ctttagaatt tgcataacta tatgctacat tctttatttc taatatatcc
     3301 attattttct cctaacttat ttttgataag atttctttag gcttcttgat taacattaat
     3361 gaagaagcaa atacaactga taaaacaata atacttatta atattaaata actttgtcca
     3421 agtgttgtta tatttgacat aaaactacta ttatttatta aacttccacc ggaaatcatt
     3481 gaatcctctg agttaatgaa tccatctaca attactttta gtaatacatt tcctaaaaat
     3541 aaggaagata ttatacttgg tatcgatatg aatattaact cgaatataaa ttgcattata
     3601 atttgtatct tagatgttcc aatagataag aatataccta tttcataaat tctttccctt
     3661 aaccatagaa tcaagattaa tgaaagaaca accatcccac ctaacataat agaataagtc
     3721 attactttta ttatatattt tattccactc actgactcta aagactcttc aaacgcatta
     3781 gaatcttttt caacaaaata ctttgactca tcaattttaa gctctttcaa tttgtttaag
     3841 gctaagtctg tagattctgc actaccagaa tacattaaaa ttttatttgc aatttcatta
     3901 ttttctgaat tatttaatat ctcttggctt gttgaataat ctacaaacac catattttca
     3961 ctaaaatcag aagataatcc tgtatatgtt tcctgttttt taccagaaaa gatccctata
     4021 attttaaatt tatgactttt tatttttcca cttttttcaa tatctagtaa ttcaagatca
     4081 acttcatcac ctaattttag attgttttgt ttagcaaatt cttcatgaac aataattgaa
     4141 ttcttatcat tttcttctat atttttacct tctttaattg taaatactcc actactaaat
     4201 aaaatatttc ttttagtatt atttgtagct tcgagtgaaa caacattctt aaattcgtca
     4261 gataaatctt ctctatttat tctttgttct ccgctaacta ctttagcatc ttttagtttt
     4321 gctaatccat catattgaat tattttttct tcaatttctt ttaatttttc aatatcttta
     4381 aattgattaa cattaaaata tttaccatct ttttttgtta ttgatattga agaattagaa
     4441 ctttcatata aagccttttc tatttcattg cttgatttca ttattgttaa acaagaatac
     4501 aagcaagaaa gaactatagt taatatgata aaaattatta aagttctatt tttctttctt
     4561 gtaatatatg ctatagcatt ttttatcact ttcctaacta ctcctctcta ttttcttact
     4621 ccataactaa ttgcatccac tggacaagca tttttacatc gtccacatct gatacactcc
     4681 agatgattgc aattctcaac tgaatcttta ttcatttggc aaactttttt acattttcca
     4741 caattaatac acttatcctt atcctgaatc ggctacacta gactagacag aaaaaataag
     4801 gtgtgtagaa taataaaaaa cacactggag gatttttcat g
//
LOCUS       DADLIO010000124         4785 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.131, whole genome shotgun sequence.
ACCESSION   DADLIO010000124 DADLIO010000000
VERSION     DADLIO010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4785)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4785)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4785
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.131"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            51..746
                     /gene="vanR"
                     /locus_tag="JOX41_002746"
     CDS             51..746
                     /gene="vanR"
                     /locus_tag="JOX41_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HAY6450426.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            724..1878
                     /locus_tag="JOX41_002747"
     CDS             724..1878
                     /locus_tag="JOX41_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HAY6450427.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            2093..3061
                     /locus_tag="JOX41_002748"
     CDS             2093..3061
                     /locus_tag="JOX41_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HAY6450428.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            3054..4085
                     /gene="vanA"
                     /locus_tag="JOX41_002749"
     CDS             3054..4085
                     /gene="vanA"
                     /locus_tag="JOX41_002749"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HAY6450429.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            4091..4699
                     /locus_tag="JOX41_002750"
     CDS             4091..4699
                     /locus_tag="JOX41_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HAY6450430.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT         1478 a          916 c         1119 g         1272 t
ORIGIN      
        1 tataatctga taaattatta agggcaaact tatgtgaaag ggtgataact atgagcgata
       61 aaatacttat tgtggatgat gaacatgaaa ttgccgattt ggttgaatta tacttaaaaa
      121 acgagaatta tacggttttc aaatactata ccgccaaaga agcattggaa tgtatagaca
      181 agtctgagat tgaccttgcc atattggaca tcatgcttcc cggcacaagc ggccttacta
      241 tctgtcaaaa aataagggac aagcacacct atccgattat catgctgacc gggaaagata
      301 cagaggtaga taaaattaca gggttaacaa tcggcgcgga tgattatata acgaagccct
      361 ttcgcccact ggagttaatt gctcgggtaa aggcccagtt gcgccgatac aaaaaattca
      421 gtggagtaaa ggagcagaac gaaaatgtta tcgtccactc cggccttgtc attaatgtta
      481 acacccatga gtgttatctg aacgagaagc agttatccct tactcccacc gagttttcaa
      541 tactgcgaat cctctgtgaa aacaagggga atgtggttag ctccgagctg ctatttcatg
      601 agatatgggg cgacgaatat ttcagcaaga gcaacaacac catcaccgtg catatccggc
      661 atttgcgcga aaaaatgaac gacaccattg ataatccgaa atatataaaa acggtatggg
      721 gggttggtta taaaattgaa aaataaaaaa aacgactatt ccaaactaga acgaaaactt
      781 tacatgtata tcgttgcaat tgttgtggta gcaattgtat tcgtgttgta tattcgttca
      841 atgatccgag ggaaacttgg ggattggatc ttaagtattt tggaaaacaa atatgactta
      901 aatcacctgg acgcgatgaa attatatcaa tattccatac ggaacaatat agatatcttt
      961 atttatgtgg cgattgtcat tagtattctt attctatgtc gcgtcatgct ttcaaaattc
     1021 gcaaaatact ttgacgagat aaataccggc attgatgtac ttattcagaa cgaagataaa
     1081 caaattgagc tttctgcgga aatggatgtt atggaacaaa agctcaacac attaaaacgg
     1141 actctggaaa agcgagagca ggatgcaaag ctggccgaac aaagaaaaaa tgacgttgtt
     1201 atgtacttgg cgcacgatat taaaacgccc cttacatcca ttatcggtta tttgagcctg
     1261 cttgacgagg ctccagacat gccggtagat caaaaggcaa agtatgtgca tatcacgttg
     1321 gacaaagcgt atcgactcga acagctaatc gacgagtttt ttgagattac acggtataac
     1381 ctacaaacga taacgctaac aaaaacgcac atagacctat actatatgct ggtgcagatg
     1441 accgatgaat tttatcctca gctttccgca catggaaaac aggcggttat tcacgccccc
     1501 gaggatctga ccgtgtccgg cgaccctgat aaactcgcga gagtctttaa caacattttg
     1561 aaaaacgccg ctgcatacag tgaggataac agcatcattg acattaccgc gggcctctcc
     1621 ggggatgtgg tgtcaatcga attcaagaac actggaagca tcccaaaaga taagctagct
     1681 gccatatttg aaaagttcta taggctggac aatgctcgtt cttccgatac gggtggcgcg
     1741 ggacttggat tggcgattgc aaaagaaatt attgttcagc atggagggca gatttacgcg
     1801 gaaagcaatg ataactatac gacgtttagg gtagagcttc cagcgatgcc agacttggtt
     1861 gataaaagga ggtcctaaga gatgtatata attttttagg aaaatctcaa ggttatcttt
     1921 actttttctt aggaaattaa caatttaata ttaagaaacg gctcgttctt acacggtaga
     1981 cttaataccg taagaacgag ccgttttcgt tcttcagaga aagatttgac aagattacca
     2041 ttggcatccc cgttttattt ggtgcctttc acagaaaggg ttggtcttaa ttatgaataa
     2101 catcggcatt actgtttatg gatgtgagca ggatgaggca gatgcattcc atgctctttc
     2161 gcctcgcttt ggcgttatgg caacgataat taacgccaac gtgtcggaat ccaacgccaa
     2221 atccgcgcct ttcaatcaat gtatcagtgt gggacataaa tcagagattt ccgcctctat
     2281 tcttcttgcg ctgaagagag ccggtgtgaa atatatttct acccgaagca tcggctgcaa
     2341 tcatatagat acaactgctg ctaagagaat gggcatcact gtcgacaatg tggcgtactc
     2401 gccggatagc gttgccgatt atactatgat gctaattctt atggcagtac gcaacgtaaa
     2461 atcgattgtg cgctctgtgg aaaaacatga tttcaggttg gacagcgacc gtggcaaggt
     2521 actcagcgac atgacagttg gtgtggtggg aacgggccag ataggcaaag cggttattga
     2581 gcggctgcga ggatttggat gtaaagtgtt ggcttatagt cgcagccgaa gtatagaggt
     2641 aaactatgta ccgtttgatg agttgctgca aaatagcgat atcgttacgc ttcatgtgcc
     2701 gctcaatacg gatacgcact atattatcag ccacgaacaa atacagagaa tgaagcaagg
     2761 agcatttctt atcaatactg ggcgcggtcc acttgtagat acctatgagt tggttaaagc
     2821 attagaaaac gggaaactgg gcggtgccgc attggatgta ttggaaggag aggaagagtt
     2881 tttctactct gattgcaccc aaaaaccaat tgataatcaa tttttactta aacttcaaag
     2941 aatgcctaac gtgataatca caccgcatac ggcctattat accgagcaag cgttgcgtga
     3001 taccgttgaa aaaaccatta aaaactgttt ggattttgaa aggagacagg agcatgaata
     3061 gaataaaagt tgcaatactg tttgggggtt gctcagagga gcatgacgta tcggtaaaat
     3121 ctgcaataga gatagccgct aacattaata aagaaaaata cgagccgtta tacattggaa
     3181 ttacgaaatc tggtgtatgg aaaatgtgcg aaaaaccttg cgcggaatgg gaaaacgaca
     3241 attgctattc agctgtactc tcgccggata aaaaaatgca cggattactt gttaaaaaga
     3301 accatgaata tgaaatcaac catgttgatg tagcattttc agctttgcat ggcaagtcag
     3361 gtgaagatgg atccatacaa ggtctgtttg aattgtccgg tatccctttt gtaggctgcg
     3421 atattcaaag ctcagcaatt tgtatggaca aatcgttgac atacatcgtt gcgaaaaatg
     3481 ctgggatagc tactcccgcc ttttgggtta ttaataaaga tgataggccg gtggcagcta
     3541 cgtttaccta tcctgttttt gttaagccgg cgcgttcagg ctcatccttc ggtgtgaaaa
     3601 aagtcaatag cgcggacgaa ttggactacg caattgaatc ggcaagacaa tatgacagca
     3661 aaatcttaat tgagcaggct gtttcgggct gtgaggtcgg ttgtgcggta ttgggaaaca
     3721 gtgccgcgtt agttgttggc gaggtggacc aaatcaggct gcagtacgga atctttcgta
     3781 ttcatcagga agtcgagccg gaaaaaggct ctgaaaacgc agttataacc gttcccgcag
     3841 acctttcagc agaggagcga ggacggatac aggaaacggc aaaaaaaata tataaagcgc
     3901 tcggctgtag aggtctagcc cgtgtggata tgtttttaca agataacggc cgcattgtac
     3961 tgaacgaagt caatactctg cccggtttca cgtcatacag tcgttatccc cgtatgatgg
     4021 ccgctgcagg tattgcactt cccgaactga ttgaccgctt gatcgtatta gcgttaaagg
     4081 ggtgataagc atggaaatag gatttacttt tttagatgaa atagtacacg gtgttcgttg
     4141 ggacgctaaa tatgccactt gggataattt caccggaaaa ccggttgacg gttatgaagt
     4201 aaatcgcatt gtagggacat acgagttggc tgaatcgctt ttgaaggcaa aagaactggc
     4261 tgctacccaa gggtacggat tgcttctatg ggacggttac cgtcctaagc gtgctgtaaa
     4321 ctgttttatg caatgggctg cacagccgga aaataacctg acaaaggaaa gttattatcc
     4381 caatattgac cgaactgaga tgatttcaaa aggatacgtg gcttcaaaat caagccatag
     4441 ccgcggcagt gccattgatc ttacgcttta tcgattagac acgggtgagc ttgtaccaat
     4501 ggggagccga tttgatttta tggatgaacg ctctcatcat gcggcaaatg gaatatcatg
     4561 caatgaagcg caaaatcgca gacgtttgcg ctccatcatg gaaaacagtg ggtttgaagc
     4621 atatagcctc gaatggtggc actatgtatt aagagacgaa ccatacccca atagctattt
     4681 tgatttcccc gttaaataaa cttttaaccg ttgcacggac aaacggttct gttgcaaagt
     4741 tttaaataaa gaataaaatc ccttacggta tctatgattt aagct
//
LOCUS       DADLIO010000125         4779 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.132, whole genome shotgun sequence.
ACCESSION   DADLIO010000125 DADLIO010000000
VERSION     DADLIO010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4779
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.132"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(90..728)
                     /locus_tag="JOX41_002751"
     CDS             complement(90..728)
                     /locus_tag="JOX41_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAY6450431.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(851..1483)
                     /locus_tag="JOX41_002752"
     CDS             complement(851..1483)
                     /locus_tag="JOX41_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAY6450432.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            1834..2133
                     /locus_tag="JOX41_002753"
     CDS             1834..2133
                     /locus_tag="JOX41_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAY6450433.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            2628..>4779
                     /gene="acm"
                     /locus_tag="JOX41_002754"
     CDS             2628..>4779
                     /gene="acm"
                     /locus_tag="JOX41_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HAY6450434.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQK"
BASE COUNT         1815 a          696 c          837 g         1431 t
ORIGIN      
        1 ttttaatcca ttgatacatc tgtctttttg tttaaaggaa ataaagtatg ctttcttagc
       61 aatagagcat gtattatttc tataaaaatt taggagaata aaacgactag caatatagct
      121 gtgaaatcaa atatcacatg aactgcccaa cttgtaatga tcgagttgct tttaatggca
      181 gcttggttga ataacaatct tgccacccct tgtatcaaaa ggatgtgtgc tacagtgtgt
      241 aaaatatttc cattatcata agtactgtaa tggataaatc caaagatgat tgctgacaag
      301 aaactagcga caggaatgct gaacttacta gaaaaaatag cgagaaaata cactgagaac
      361 aattcttctc caagtatcat gataggcaaa ataataaata ataacgggct gaaagcctca
      421 tttattggat tgcctgttaa accccatttc aaaatttgtt gcaaaaatac cgagactgcg
      481 gcactgatta ctacattgat aaaaaaatat ttggctatat ttttgacagg agcgacaggt
      541 ttcgagaaca tttttttcgt atctttttta ccaaaaacaa gtgtaaatgc tataaatcca
      601 gtgatagtta aagaaaaaat gctaataatg gatggcgcaa atagcaaccc taacaaaccg
      661 agtacaacga caatagtgcc caatatccct tttttaagtt ctattttttt tcctaaaatg
      721 ttattcatga taataactcc tactattcag tttttgaaga tagagtcagt atacatgaag
      781 agttaaaata ggcaatgttt ttttatggat atttgtattg ctaaaaattt atcttatata
      841 ttcattttga ttatactact tttatttgta aaaattttct agcaaaacca agtgcttgca
      901 actgattaag cgtacaattt tttagatgtt ccgagcgtac ttcaatcatt tcaaaggagt
      961 tgctacttaa atcgatattt tttaaatcag tatcaaaaaa gctagcattt tctaaatcat
     1021 tagtagaaaa cattatttta gtgagggaac agtctacaaa atctgcgctt gataagacag
     1081 agtgctcaaa ggtactttct tttatgtttg aaccagataa atttacatag tccattttac
     1141 aattctcgaa taacgtgttc ccaatataac tttccatcaa tttagtacct gttaatttac
     1201 aattgacaaa tttcacgcga tgcaacatgc tttttgtcaa tatacagcct gaaaaatcac
     1261 agttttcgaa tatacagtcg gtaatctcca ttctttgaaa atcattggaa gcaaaaaatg
     1321 catacttgaa aatagatttg taaataattg gatggcagat tatttggttt tcgatgacct
     1381 ctttttgtga aaggatatta tacagttcaa aatcttcgtt ttcatagata tgaaaaaagg
     1441 atcctttatt caagcttgct tcattaactt taggaaaaat catatttaat tacctccatt
     1501 ttcataaagt catattaaca aaagctaaac caacttacat tagcagaaaa tgagataggt
     1561 tttcgccttt ttcgataacg atagtgtcgc tatctcttga aacgttctta gaattgccct
     1621 gagagacaca aattaggcgt aattctaata aaaatcttag aataaaaatt tttactgatt
     1681 taatttagaa tgtttttaaa ataaaaatcg ttgccataac agtgtattga aaggttttaa
     1741 caatccagta atgatttaaa aaaatctaga tgtagcgtat actttgttta tagaatgtag
     1801 tgggaagaaa tatatttttg ggaggaaatc gtgatgtcta aaagtgaaga aatagaaaac
     1861 atggtactaa aattatatga tctcgtttta aatccagaga tcaaagaaaa ggaacgtata
     1921 cttttgatag acgcaaagac aggcttagaa aaaggtcagt attatcctaa agtcataaat
     1981 aatttggaac gtagtttacg tccgttagca atcaggggag aattgtctaa accagtatca
     2041 ccgttttata tggagatatc aacaatagga aaatttgaaa aagaattagg tcgaggaatg
     2101 gcttcggcac cgattacttt tgggcattta taaaaacgag ttattcatct caatgaatta
     2161 aaaagtatag tcaatctcat aatgcaggct aggttcattt atttgaacag agtctgtatt
     2221 tttttattct aaataaagaa acagatgttt ctttatattg tattttatcc tttaattaac
     2281 acaaaaacag ctagtataaa ctaataatgt taattaaaag tgtattttat gaaactatcg
     2341 ttatttatta atgttgcatt tttgtaagtt aaaaattgga aatatagatt gaaaaaatga
     2401 aagcaataag taaaataaaa tgaatatatg cgaaaaaata atttacatta ggaaaaacct
     2461 tgtaaaaaca gttttttggc atatttattt tttataaata tttgtaaaat aactatcaat
     2521 tttttagtta aaagattgga aatgagtggg ggaggaattg aagaaaggat ttttgagaga
     2581 tgatatagta ggttttattt ttagttaaaa taggggagat agaaaaaatg aaaaagtgta
     2641 gaaatattat tttatcaatg ttatttatta ttactaatat aacatcactg attcctgttc
     2701 atgtctatgc ggatgcaggc agagatatca gcagtaatgt cacttcgttg accgtggacc
     2761 caacgaatat tacagatgga ggaaacataa aagtaaaatt ctcgtttgac gaaaaaaaac
     2821 aaaatatcca accaggtgat tatctttgga tcaattggcc aagtgaagga aatattcgcg
     2881 gtgaaggatt ccaaaaagaa atcccattaa tgattgaaaa taaaaatgtt ggaactttaa
     2941 cggtcagaaa agattctgcg caggttgtgt ttaatgaaaa tattaaaaac ctagactcag
     3001 tagaaggttg ggggcaattt gagatacagg ccagaaacgt aaccgatacc ggtgaagaaa
     3061 atacgggacc attcaccgtg acgagcggtg ataaaacagc tactgtaaat gtgacaaagc
     3121 cagcttctgg ttcttcttct agcgtttttt attataaaac aggagacatg ctacctgaag
     3181 atactaagca cattcgatgg tttttgaata ttaacaataa cggcacttat gttgaacaac
     3241 cagttaaaat cagtgatgaa atccaaagtg gacaaagatt agatccaagt acgtttgaaa
     3301 ttaatcaaat acacttaggt gaacagaagg tttatagagg agaagaggga atccaacaat
     3361 ttttacaaga tttccccagc gctacattta atttttcagt aactgataat tacattgaaa
     3421 taactatacc aaaaaacttt gtcaatctta ggaaaataat ggtgagttat aagacgatca
     3481 tagaaaaccc agaacaaata aattttgaga atcattcgga agcttggttt aaagaattta
     3541 ataaacctgc tgttgatgga gaaagtttca atcatacagt taaaaatatt tcagcttctg
     3601 gtggagtcaa cggtacagtt agaggcgaat tgaagatttt caaatatatc aatgacacag
     3661 agattggtat cccaaatgtg actttcgaat taagacgagc agatgaacag cctattcaag
     3721 gacagtctag tatcctgttg acttcgaatg aacagggaga agctagtatc aaaggcctgc
     3781 aagtaggaga ctatgttgta aaagaaaaag aagcacccaa ttggattgat tttgatccac
     3841 taagttcaaa tgaactcaaa ttctccataa acgaaaatga tacagaggga gtcagtttac
     3901 ctatttataa caagaaaaag gttacgaaca tcacagcaac taaaatttgg aacggtggaa
     3961 ccactccaag accgagtatt tattttaaat tattcagagc aagtacaaac aattgggaac
     4021 cagttcctga tgcagaaaca aaacgattag acaatggaat aacttcagtg acttgggaag
     4081 atatccaaca gtatgatgat agtggaaacg aatatacgtt taaagtgcaa gaagtagatc
     4141 aaaacggaaa tgattatgtc ccttcaggtt atcaaaaaat tgaaaacggg ctagtcgtta
     4201 caaatgagaa taaagaagtc atttcagtct caggacaaaa aacatgggaa gacaatgaga
     4261 accaagacgg caaacgaccg acgacgatca cagtaaatct attagccgac ggtcaaccga
     4321 tccaacacaa agaagtaagt gaaaaagatg attggcgcta tcgtttcaca aatctgccaa
     4381 aatacagaga cgggcaagaa atcatctata ctgtaacgga agacaacgtg cccgaataca
     4441 gtacgacgat tgacgggtat aacatcaaaa acagttatac accggaaaaa acaaatatat
     4501 ctataccagg tagccatata acaccgtgga aaaattttcc agagaagaca gagagagaga
     4561 aaattagaaa tctattctct caaaaattgc aaatatttgc tcatacagga gaatccagcg
     4621 aacaaagaag caattatatt agtaagagag ctgtacctaa acagataaca aataaatcaa
     4681 aaagcattct tcctaaaaca agtagtaaaa aatctagttt tgctgtaatc attggtttat
     4741 tgatagtaac tatctgtgct gggatattct tacaaaaat
//
LOCUS       DADLIO010000126         4539 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.134, whole genome shotgun sequence.
ACCESSION   DADLIO010000126 DADLIO010000000
VERSION     DADLIO010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4539
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.134"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(1014..1304)
                     /locus_tag="JOX41_002755"
     CDS             complement(1014..1304)
                     /locus_tag="JOX41_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450435.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            1646..1942
                     /locus_tag="JOX41_002756"
     CDS             1646..1942
                     /locus_tag="JOX41_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450436.1"
                     /translation="MQIGVLKWLQFTKQKGVHFPMQFLEPKNKNAKSVDWEISEQVRV
                     IVKQYAEYAERTESEAVDEFLLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            1949..3901
                     /locus_tag="JOX41_002757"
     CDS             1949..3901
                     /locus_tag="JOX41_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HAY6450437.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3973..4470)
                     /gene="dfrG"
                     /locus_tag="JOX41_002758"
     CDS             complement(3973..4470)
                     /gene="dfrG"
                     /locus_tag="JOX41_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HAY6450438.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
BASE COUNT         1554 a          797 c          750 g         1438 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tatagattta agtagttcag ttttggagta caaaaagtga
     1501 aaatgtaaac ctaaatgagt atcaaattgc aactgaattt gatactcgtt ttttattgtt
     1561 aaatcaacgt ttgttgttaa tttacaccac aaaatgtaag ttaaaatgta tataaaaatg
     1621 cgaacgtgaa ataattattg taggaatgca aattggtgtg ttaaaatggt tacaatttac
     1681 taagcaaaaa ggggtgcatt ttcctatgca atttcttgag ccaaaaaata agaacgctaa
     1741 gtctgtggat tgggaaatat cagagcaagt aagggtgata gttaagcaat acgctgaata
     1801 tgcagagcgt actgaaagcg aagcagtgga tgaattctta ttgaacattt tagacgataa
     1861 gaagtttatt gaatggattg ccaacaagcg aagtaataag cggattgttg aaaaaatggg
     1921 tatcaaagat agagtgggtt gatagacaat gaccaagctt aaaagattag ccacgaagga
     1981 agatgaaatt gtagatgtta aaattccgat ttcaaacgaa gaattaaaag atagggctaa
     2041 acaatatgat ttattaactc caaaacgatt tgcaacaagg tataacaaaa tgttgttctt
     2101 gccaacgtct tttaaatgga acggttctga atatcccatt caatataatt actgcatcaa
     2161 tccgttttgt tgtaattttg ggaaagaaca gcacaaattc aaagatgtaa aagggaaacc
     2221 aagtcgatat aaaatgactg gtagttccaa agataaaggt cataaaggta tgtactgcaa
     2281 tgacaatcct attggcagag gtgtatcgca aaactgtaca gtaacccctt tatctaattg
     2341 gtctgttgtt gaagaaatta aacgccttat agaaatcaat agcatccaag atgttgagcc
     2401 agattatcaa tttcataaag aaggctgctc ggaagaagaa tcaaccccat tcaatgagcc
     2461 gaagcaattt tacaaaaggg ggaaaagtag gggcaaatct caacgctatc aatgtaaggc
     2521 gtgtaagaag ttcactaatg ttctaccaaa aagagaagaa accactactt atcaccaaca
     2581 aaagaacacc attcttccaa tgttcgctaa gatggttgtt ggaagggttt cagtcagtcg
     2641 tacttgtgat attttaggaa ttggagttgg aacctactat cataagctgg agtggctgta
     2701 taggcgttgt ttggagtttt tagaacgata tgagacacaa ccccttcaaa caaagaaatt
     2761 taacgagatg tggcttaata cggacaagat gcactactac ctaaataacg tccgtaagaa
     2821 aggacaaggt tcaaagaaat atacggggtt tgaagacctt aatatgcaaa cgtatatagt
     2881 tgtatctgct gaggtcttat caagatatgt gttccgttct gatgttgcct atgattggaa
     2941 tatttcaatg gatgaattaa atgaagatac aagaaaattc aaagaagacc atctcaatac
     3001 ttttagtcgt aaaaatgata ggttagattg gtcttattat ccacaagaac catccgctaa
     3061 cgatagcgaa aataggaatg cttatcttca cgaattaggg aaaattacta ataggagtag
     3121 atttgtcgat ggtttaaatg ttgatgctcc ttatactaca actgctcact attggttaat
     3181 taaacaaatg gttaatgccg acgaatggcg aatgattagt gatgatgact tctctattag
     3241 aaacgccttt tatagagtat tcacgaaaga attaaggttg agcgatgcac atcattttat
     3301 ttgccaagtt aacaagacga aaagcagaaa acaatgctta aaagaattcg gacaagcaaa
     3361 agcagaactg ctcgattggg gagatatcag aggattcaaa acaaagtttc tacggacttt
     3421 ggcatctcat tatctaactg aattactaac aagtcatcaa ttccacgaag aggctattag
     3481 taaagatgga gaaagatatc gcaaatatgc cgataaccct atcaaacatc cattagccac
     3541 taaggataaa ggattttatt cagttgattg tagaacggat ttatctgctc tggaaccaaa
     3601 cgaaatcgca aagatgctat taaatgttaa tgaccattcg accaatagct ttattcaaca
     3661 gataagacgt tatatatcat ctcttgaaag accattaaca acagctcgtg gtgataagaa
     3721 gagctatatt tacgctaact tcaatccgaa gtatgctcaa tttgcgatta caattctaag
     3781 aacttactac aacttttgtc gcccttttaa atcagcggat aaaaaggttt tgacacctgc
     3841 tcaaagatta gggattacag ataaacaatt tgattggaaa gatataattt atttcaaatg
     3901 acaaaaagag cttggagtaa tcccaagctc ttgtgcttta tctttactgt tcttcttcaa
     3961 ttaacgcacc cgttaactca ataagttttt tctttcatat acatgaaaat agtagttata
     4021 cggattttta tcattcttta tccctttttg ggcaaatacc tcattccatt cctcataatt
     4081 cacttctgga aaaaaagtat ctccttcgaa ttcatgatgt atttttgtga tgtacatttt
     4141 ctcaacataa gggaaaaaca aattataaat ctgttctcct ccgaaaataa aaatttcttc
     4201 ttcgttttta cataactcaa aaacatcttc tattgaatga acaatttcac aaccattaaa
     4261 ggtaaacccc ttatctctcg tcagaataat atttcttctg tcaggtaagg ctcttccgat
     4321 tgattcaagg ttcttcctac ctaatattat cggatgtccc tttgtagtat ttttaacata
     4381 ttcccagtcc ttgggaatcc tccaaggaat gtcattctct ttgccaatca ctctattctt
     4441 atccatcgca gcaatcaaag aaactttcat ttataacaca gcctttttaa ctaatttacc
     4501 atctaatttc ttatttctat caaaaaacct tttctcatt
//
LOCUS       DADLIO010000127         4461 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.135, whole genome shotgun sequence.
ACCESSION   DADLIO010000127 DADLIO010000000
VERSION     DADLIO010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4461
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.135"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            574..1008
                     /locus_tag="JOX41_002759"
     CDS             574..1008
                     /locus_tag="JOX41_002759"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450439.1"
                     /translation="MKNKIIKIITCLFLFGMIVGASTPLNLFPFSARGIKVEAASSRY
                     NHNHRGFTCYKMNYYVTNKMCRDLKKNYNKLKTPAQIASFIPIGGVGTWVITNAFSSA
                     VDAMNVFVRAANQGKGVQLTYNAHFSNTTSYQYNDYARYVIK"
     gene            2298..3221
                     /locus_tag="JOX41_002760"
     CDS             2298..3221
                     /locus_tag="JOX41_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAY6450440.1"
                     /translation="MANEIVKYENRLNHIPLRKFNSREMNLFFSIASRVREKGVDEII
                     FSFHDLKKLSGYTERGEQFIKDLSSTYDKLLSINAWNDDGNTLTKFVAFTKYSIIRDK
                     QLVIISVNPEFKGLFNQLKNWTRFNLEQFTNLDSTYSKTMFRLLKQYRTQGWTEFSKE
                     KFFDLLDIPKSYWNSPSNIDKFILRPIKEELTPLFKGLTIRKKYGKGRGKPVIGYRFT
                     WKAEINHADDFSKGKQEDLRIKLFNIDHNGELTREEKWRAKDRILNLPLGTHEADFKQ
                     QQQTEEKQAEKRELSNKLKQDLLGNLQNLFD"
     gene            3237..3776
                     /locus_tag="JOX41_002761"
     CDS             3237..3776
                     /locus_tag="JOX41_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HAY6450441.1"
                     /translation="MADKTIKELAEELGVSKTAINKKVSDKNRKLWFAKNGNKFVINE
                     TGQKAIKSMFLVDNANLNRKLVGEKSKTKNHKNTNQVSELKLLSFLEKQLNRKDIQLQ
                     EKDNQIKQMQKLLDQQQQLTLQANQQIENLQEQLHLTYTEETPTTESTAFSEKKADNT
                     QPLIEKKWWQIWKSNRTNL"
BASE COUNT         1664 a          667 c          758 g         1372 t
ORIGIN      
        1 aaaaaaaact gtgttggtac tgggttctat ttctctagga atattaggtt ttagccccat
       61 gctattatcc gtaattggaa aaaacaattc caacagagaa cttaaattga attcaaatta
      121 ttacaacagt cctaacgaag aattgtttgt aaaagaaacg gataaataat aaaaaagact
      181 gctcttccga gcagccagtt aaaaaataat gagtgtttat tcttgaaaaa gcaacgcgct
      241 tataaagcgc taccaaaaat ttatcatatt ttatgaaaaa taacaatcca gtaaaaaatg
      301 actggtaaaa attcacaaag aaacggaaag aagcaactgc agaaaatcaa gccttaaaaa
      361 gagcttttta cctagaccaa ttaaaaatca caaagtgagc ccctgtatcg gttgatacaa
      421 gggctacttg gcatactgta cattatgtct actaaccttt aaaataacac gttttataaa
      481 ataaaccctc ttgacaatat ttaattttct gattattcta aatatataca gaaagcgctt
      541 tcctaggatt ttatatctaa ggaggaagta acaatgaaaa ataaaattat taaaattatt
      601 acttgtctat ttttgttcgg tatgattgtt ggagcaagta ctccgttaaa tctgtttcct
      661 tttagtgcta gaggtataaa agtggaagct gcaagttcac gatataatca taatcatcgt
      721 ggatttactt gctataaaat gaactattat gttactaata aaatgtgtag agatttgaaa
      781 aaaaattata ataagctaaa gactcctgct caaattgcat cttttattcc tattggtgga
      841 gttggaacat gggttattac aaatgctttt agtagtgctg ttgatgcaat gaatgtcttt
      901 gtaagagctg caaatcaagg aaaaggtgta caattaacat ataatgctca ctttagcaat
      961 acaacatcat atcaatacaa tgattacgct cgttatgtaa taaaataatc agaaagtgaa
     1021 actatctcat gaataaaaag attttagctg taattatttc aataatagtt ttaatcacta
     1081 tgttcttcat atttaggcta attttcaata taagcttaca aaaaagtatt ctttatctaa
     1141 ttcctatagc atttatctta gcaattttta gaagtattta cggaaataaa aactctaaat
     1201 agctaaaaat aaatcatact aaattttaca aaaagtggct agcattttct agccactttt
     1261 tgtattgtgg agcgtgggtt ttgaggggga ttcaaggggg agcttgcgcc cctttgacaa
     1321 gcggttattt gcaccaaata cggaggtatt tggctagcaa atatagagct tgccaaaccc
     1381 ttttagtgag ttttgtagaa agtaccttta aaggtacttt cacattacga acgatacgtc
     1441 cgtaggacgt actgaaaggg tgggacttat gagcaaatta atgcaaaatt tggctagcaa
     1501 aaaagctaaa aaatatatgc taataatcga gcgaaataaa cactttttca agtgagcgaa
     1561 tccgccatga caaagctgaa gcagtttatt tcagctttgt catggcgtgt gccgactttt
     1621 ttaaaagtct aggcacacga gcaaatatct ttatcaagct ctaatttgcg ttttaagacg
     1681 tttgaaacgc ctaagtatat aaatatataa gaataggttt aagagtgctt aaatcgaatt
     1741 ttagagggca tttagacaat tttagggttg ttagggcttg ccctgaccgc ctgtaaggcg
     1801 ttttaagaac aagataaggg atttatacta ggactgtctt aaaatgtctt aaacgaacgc
     1861 tcagagcttc tcaaagggtt ccttatgaac ggcttttagc aaaggagccg gaggcgactg
     1921 cgcagtataa tgtgagagca gagcgatcac acctttttag cgaaccgtag ggagcaaggt
     1981 ttggaattgg cagttttgat aaattcgcga acctgtttag agaaaaaagg agtgattttt
     2041 taggcgggaa aattagcctc ccctcttttt atatctcttt ttatatctct ttttatatct
     2101 cttttatgtc ggctgtgtcc ttactctccc aagcaattca gagttttttc aagtaggttt
     2161 tctacgcttt tcaagtaggt tttctacgct tttcaagtag gttttctacg cttttcaagt
     2221 aggttttccg acattattga gtatttttat aaagtatgtt acttttattt catactttat
     2281 aaaagtagga gaagcttatg gcaaatgaaa ttgtaaaata tgaaaataga ttaaatcata
     2341 ttcctctgag aaaatttaat agtcgtgaaa tgaacttatt tttttcaatt gcttcacgtg
     2401 tacgtgaaaa aggtgtagat gagattattt tttcatttca cgatttgaaa aaactaagcg
     2461 gttatacaga acgtggggaa caatttataa aagatcttag tagcacgtat gacaaattat
     2521 taagtattaa tgcttggaat gatgatggaa atactttaac taaatttgtt gctttcacaa
     2581 aatatagcat tatacgagat aaacaacttg ttataatttc agttaatcca gaatttaaag
     2641 gactttttaa tcaattaaag aactggacaa gatttaatct agagcaattt actaatttgg
     2701 atagcacata ttcaaaaact atgtttcgat tattaaaaca atatcgaact caaggctgga
     2761 ctgaattttc caaagaaaaa ttttttgatt tactagatat tcctaaaagt tattggaata
     2821 gtccgtcaaa tattgacaaa tttatcttaa ggccaattaa agaagaactc actcccttat
     2881 ttaaaggatt aactattcgt aaaaaatatg gtaaaggtcg aggtaaacct gttatcggtt
     2941 atcgttttac ttggaaagct gaaattaacc atgctgacga tttttccaaa gggaaacaag
     3001 aagatttacg tataaaatta tttaatattg atcacaatgg agaattaaca cgagaagaaa
     3061 aatggcgcgc taaagatcga atactaaatc ttcccttagg cactcatgaa gctgatttta
     3121 aacaacaaca acaaactgaa gaaaaacagg cagaaaaacg agaactttca aacaaactca
     3181 aacaagattt actaggaaat ttacaaaact tattcgatta agcttaagga gtatttatgg
     3241 cagataaaac aatcaaagaa cttgcggaag aattaggagt tagtaaaaca gcaattaaca
     3301 aaaaagtttc tgacaaaaat cgaaaacttt ggtttgcaaa aaacggaaac aagtttgtga
     3361 ttaacgaaac cggtcaaaaa gctataaaat caatgttttt agtcgataac gcaaacttaa
     3421 atcgaaaact agttggcgaa aaatcaaaaa ccaaaaacca taaaaacacc aaccaagttt
     3481 ccgaattaaa actcctttct ttcctagaaa aacagttaaa tcgaaaagat atacagctac
     3541 aagaaaaaga taatcaaata aaacaaatgc aaaaattact cgaccagcaa caacaactca
     3601 ctctacaagc gaaccaacaa attgagaacc tacaagaaca gctccattta acttatacag
     3661 aagaaactcc aacaaccgaa tcaactgcct tttctgaaaa aaaagcagac aatacacaac
     3721 cacttattga aaaaaagtgg tggcaaattt ggaaatctaa tagaaccaat ctctaaaatt
     3781 ttctagaagt tagttcggat agtagaggaa aaagttgtac tacctgatgg ggagatcact
     3841 caaattttta tgagaaagaa aaaatagttt acaactgtaa acaatcaatg tttatagttg
     3901 taaactatca aactatatgg tgacttattg cttaaaatag gttgaaatct cactcaattt
     3961 ttggtggaaa aacaaaataa attctaatcg attttgttga aaaagtcata aaaaaacaaa
     4021 tgtgatttta acaaaatttc aaaaaaatcg tttgaaattt cgtttatttt ttttgagaat
     4081 tttgatcatc gtagggtcat tgtagaatca ttatgagatc atcgtgggat catcgaataa
     4141 agtatgggaa aggcttgcgg tgcttggtat taagggcatt ctccgcctcc caggttcttg
     4201 accattttct cttataagtg ggatttttac cacgttgaga gaaaatggtc aagaacctgg
     4261 gaggcggaga aaacatacca agcaccacaa gcaaaaaaag ttagagtaac ttccaaaaaa
     4321 gaaaaatttt ttagaacaac ttttgaaaat ttaattttga tttatatccg ttcaatttaa
     4381 acatttgata aactgaaggc tagtatttaa aatgtgtata caagtggtag cgttaaaaaa
     4441 agtggaggta taacctatgt t
//
LOCUS       DADLIO010000128         4434 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.136, whole genome shotgun sequence.
ACCESSION   DADLIO010000128 DADLIO010000000
VERSION     DADLIO010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4434
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.136"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(543..2048)
                     /locus_tag="JOX41_002762"
     CDS             complement(543..2048)
                     /locus_tag="JOX41_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAY6450442.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDN
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="JOX41_002763"
     CDS             complement(2045..2731)
                     /locus_tag="JOX41_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAY6450443.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="JOX41_002764"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="JOX41_002764"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HAY6450444.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1240 a          919 c          729 g         1546 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgcat tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa aggaatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgacttggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaacat attt
//
LOCUS       DADLIO010000129         4425 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.137, whole genome shotgun sequence.
ACCESSION   DADLIO010000129 DADLIO010000000
VERSION     DADLIO010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4425
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.137"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            690..1658
                     /locus_tag="JOX41_002765"
     CDS             690..1658
                     /locus_tag="JOX41_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAY6450445.1"
                     /translation="MDVAKTVNAIVEKNDGEISGIYLVACGGSLVDMYVSDYFLKAEA
                     SKCITGLYTANEFNHVTPKQLDDKSVVILCSHGGNTAETVKAGEVAQARGAVTVGLTH
                     NKTADLLKVSDHSFLYEWGDDAKIVNNPMAIILDLTVSLVNVTETFEHYGKFREGMKV
                     IDTVIENGIKQVQDRIKVFADKYKDETMFYILGSGPSYGHAYGFSICSLMEMQWLDST
                     SVHSGEFFHGPFEVTDKDTNFILLMSIGRTRALDERAKRFLDKYAERVEIVDAKELGL
                     DMISDEVSEFFNPILFYSILSEYRSALADVRNHDLDVRRYMGKVEY"
     gene            1669..2484
                     /locus_tag="JOX41_002766"
     CDS             1669..2484
                     /locus_tag="JOX41_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HAY6450446.1"
                     /translation="MKVLGLGDNVVDKYENLGIMYPGGNSLNFAVFAKKLGHESSFMG
                     VFGSDEEAAHVLSAIKEIGLDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREY
                     PIQLTEEDREYLNQFELIHMGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAID
                     KVDFGFFSIEDFSDEEVKQFLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEE
                     PVDTMAAGDSFLTAFLLYFLEGDDIVTAMKKGNEFAGKSCLVDGSFGFGIHYD"
     gene            2552..3262
                     /locus_tag="JOX41_002767"
     CDS             2552..3262
                     /locus_tag="JOX41_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAY6450447.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYIMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            3298..>4425
                     /locus_tag="JOX41_002768"
     CDS             3298..>4425
                     /locus_tag="JOX41_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HAY6450448.1"
                     /translation="MKQILRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKIL
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIKN"
BASE COUNT         1490 a          661 c          921 g         1353 t
ORIGIN      
        1 atacaaataa ttcaccaaaa aggtgagtaa tgccattttt gaaaattgag cttgttttat
       61 gtctacatct gtatccgtat ataatccaaa ggattataaa ctcagaagag tctttatttt
      121 ttctgaatat aactactgta tcaaaaacaa tcgattatga gacaaaacaa aatgacctct
      181 tttatttaag aaaggaggtc attttttgta tcataaattg tattaaaatc aatgtatcac
      241 tttttaatca gttttaagac cataaattgc gtactaaaag aaattctgca attcaaaata
      301 aagcatttta agccattttc aaatttaagt gcacccatct acccgtcaaa tcactttatt
      361 ttccactcca gtagtttcct aattcaactg tgtgcaaaaa cgatttcttc taaacaaatc
      421 aagacaaact tataaacctt catcccagca ccataattat ttaaatcata ggcatttttc
      481 gaaattagta tatgtactca agtttcactg cagattattt atatttttta gagaaataaa
      541 tttttcctat tgacaaacac aaagaaagcg gatacaatgc aattatgtca catgacgtta
      601 tatgacgtta tgtgatatct ttacatttaa tcagttactt ttattttgga taaaattaac
      661 atttttaaaa ttttaaggag gaaatgttga tggatgtagc aaaaacggtt aacgcaattg
      721 tagaaaaaaa tgatggagag atttctggaa tttatttggt ggcttgtggc ggttcgctgg
      781 tagatatgta tgtctcagat tattttctta aagccgaagc atcgaagtgt attacaggct
      841 tatatacagc gaacgaattt aaccatgtaa ccccaaagca attagatgat aaatctgttg
      901 tcattctatg ttctcatgga ggaaatacag cagaaacggt aaaagcagga gaagtcgctc
      961 aagctagagg agctgtgact gttggtctga ctcataataa aactgcggat ttattaaagg
     1021 tttctgatca tagtttcctt tacgaatggg gagatgatgc aaaaatagtc aataatccta
     1081 tggccatcat tcttgattta actgtatctt tggtcaatgt taccgaaaca tttgaacatt
     1141 acggtaaatt cagagaaggc atgaaggtta tcgataccgt aattgaaaat ggcattaagc
     1201 aggtgcagga tcgtattaaa gtgtttgctg ataagtacaa agatgaaaca atgttttata
     1261 tcttaggtag tggaccatca tatggacatg cttatggttt ttcaatttgc tctttgatgg
     1321 aaatgcaatg gcttgattca acttctgttc attctggaga attcttccat ggaccttttg
     1381 aagtaacaga caaagatacg aattttattc tcttgatgag cattggacgc actcgtgctt
     1441 tagatgaacg ggcaaaacga ttccttgata aatatgcaga aagagtagaa atcgttgatg
     1501 caaaggaact aggattggat atgatatcag atgaagtttc tgaattcttc aatcccattt
     1561 tattctacag tattctttca gaatatcgtt cagctttagc agatgtacgc aatcatgatt
     1621 tagatgttcg tcgctatatg gggaaagtgg agtactagga ggattaaaat gaaggtatta
     1681 ggcttaggtg ataacgtcgt cgataaatat gaaaatctgg gaattatgta tcctggagga
     1741 aattcattga attttgcagt ttttgcaaaa aaactgggac atgaaagtag ctttatggga
     1801 gtttttggct cagatgagga ggcagctcat gttttatcag caataaaaga aataggactg
     1861 gacaacagtc actctcgctt tgaaaaaggc gagaatggct gtgccagagt gaagattgat
     1921 gagggcgacc ggattttcct tggcagcaat tcgggaggtg ttactcgtga atacccgatt
     1981 cagcttactg aagaagacag agaatattta aaccagtttg aattgattca tatgggatta
     2041 tatagccatg tcaatcatct attagaagag ttacaaaatg tttctggaaa gatttcttat
     2101 gatttttctg acgactttac ggaagaagag gttcagcggg caattgataa agttgatttt
     2161 ggcttctttt ctatagaaga cttttccgat gaagaagtaa agcagttttt gatgaagcat
     2221 ttttgtgagc gaaatgatgt attgattgca acccgaggag aaaaaacggc tattggttat
     2281 gatggagcaa agttttatga agtgaacccc gtgctagaag aaccagttga tacaatggca
     2341 gcgggagatt ctttcttaac agctttccta ctttattttc tcgaagggga cgatatagtc
     2401 accgcgatga aaaaggggaa tgaatttgct gggaagtctt gtctggttga cggttcgttc
     2461 ggctttggta ttcattacga ttgagcttgt tttaaattcc tgcatttgat aacctaaaga
     2521 aagaaatccc ggtaaagtgg aggttaaaaa aatgctggat acaaatgcac aattaccatt
     2581 gtacttacaa ttaaaagaaa tattaaaaaa taaaatcaat acaggggagt atcccgagaa
     2641 tacgaaaatt cccgctgaat cagagctgat agaaagttat gaggtcagcc gaatcacagt
     2701 gagaaaagca gtagaagaac tggtagaaga agggtaccta cttaaaaaac aagggaaagg
     2761 aacttttgtc aaccggcata aagtttttcg taaaattgaa tatattatgg gtttcagtga
     2821 gagttgtaaa tctaatggtt ttacaccgac tagcattgtt ttggaacgca agatcattcc
     2881 agcaactgaa gggatggcaa aaaaactcga tatcgctcaa ggtgatgatg ttttatatat
     2941 ccagagaaag cgaatggcgg ataacatccc cattatgtta gaaaacaatt atttttctta
     3001 tgaaagatat agtttcttaa tggaggaaga gctgactgat tctttgtatg aagtacttaa
     3061 agtccaaggt accttagcca tcaatcctgg ggaaactgca cttgaaattg tcacagctga
     3121 tgaccaaatt gccaaaataa tggaagtagc tgttgggacg ccctttttct ttatggatac
     3181 tttaatcaac gatcaaaaca acataccaat tcatgtaggt aatcaatatt acctgggaga
     3241 agtatatcgt ttttacttat gatttcctgt ttggatttca aggagtagat tttatttatg
     3301 aagcaaatat tgcggtcaaa aatgattttt gatggagagc agccaccttt caaaggttat
     3361 attgtaatca atgaagggat cattgaaaag gtggaaaaca actggaatta cagtgatcta
     3421 ttaaatgaaa acacggaatt aattgcttat gatgatcaat tcgttatgcc agcaattcat
     3481 gataatcatg tatttttcag tggttatttg gctatgaatg ctggcataga tttaagcgat
     3541 acatcttcag ctaacgaggc tgtagagcgt attaaagctg taatgaacca taaaaaagca
     3601 gatgaaccaa tttatgctca tggctgggat gctgccctgt ggaaaactga cccatcagaa
     3661 gagctattga atgaaataaa ccactttggt ccaatcacag cgatcgacaa aaatcgcagc
     3721 cattgttgga tgaatgctat tgctaagcag acttatggtt ttacagaaaa agaaaccagt
     3781 gctgaaagtc gagtattatt aattaaggaa atgctagcaa acaaaaagct tttagcagag
     3841 gtttacgctg aatttgaagc attactgctt tcaaaaggtg ttatatcaat gaaagaaatc
     3901 gtttttgatg acgcagaatt tctttctaat atacctcaga ggaaaatact tagtaaccta
     3961 tatgtgcagg cagtccaaga acctctacag catgaacttc tatatgagta taaggaaaaa
     4021 gttttccctg aaaaggtccg ctttggtgga gtgaagatca tggtagatgg tgttgttgcg
     4081 gatagaagtg gagatattta cggtgtttat cagtcaggag tagcttcacc cgagattgac
     4141 tatgaggcaa ttaaagcaga agttgctgca ttcaatgaag tagagattcc ttgctgtttg
     4201 acaacggaag gagataaagc gggttataaa gctgcgtcaa ttcttgtcga atttggaaag
     4261 cggttacctg aaggcgtttt taattcgatt agtgatttgg aaatggttac tcaaaagaca
     4321 gcagaaaaaa tgaacgaagg acaagtagta gcagaggtat atccacaaat tctcggcttg
     4381 aatcaaacgt tagaagaggc ttacatgtca actgttataa aaaat
//
LOCUS       DADLIO010000130         4369 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.138, whole genome shotgun sequence.
ACCESSION   DADLIO010000130 DADLIO010000000
VERSION     DADLIO010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4369)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4369)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4369
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.138"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            <1..792
                     /locus_tag="JOX41_002769"
     CDS             <1..792
                     /locus_tag="JOX41_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003065868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAY6450449.1"
                     /translation="FCGYSKTEPRHSFGPAIREQYLIHIVLEGEGYYSINDQKYFLKK
                     GQGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYYLKEIGVGKNHLTFKVENLNSF
                     KGLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSASYLNEGIITKKMNPFVRQTIEI
                     IRENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISIKEYISEIKISIANDLLSSTEY
                     SIQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRLGLGIINGE"
     gene            889..3138
                     /locus_tag="JOX41_002770"
     CDS             889..3138
                     /locus_tag="JOX41_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAY6450450.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3141..4316
                     /locus_tag="JOX41_002771"
     CDS             3141..4316
                     /locus_tag="JOX41_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAY6450451.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTRVTRGAS"
BASE COUNT         1522 a          625 c          803 g         1419 t
ORIGIN      
        1 ttttgtgggt attcaaaaac agaacctaga catagttttg gaccagctat tcgagaacaa
       61 tacttaatac acatagtgct agaaggtgaa ggctattatt caattaatga tcaaaaatat
      121 tttctgaaga aaggccaagg atttgttatc ccaccaggag tatctacttt ttatcaagca
      181 gatgaaaaaa atccgtggtc atatgtatgg ttgggtttaa gtggcaatct tgtagaatac
      241 tatctaaaag aaattggtgt tggaaagaat catcttacct ttaaagtcga aaatttaaat
      301 tcatttaaag gattaatttt tgaaacttta tcgtatgatc aggacaatct agtcagtgaa
      361 ttgtccagac aaaaacaagt ttataaattt ttagaactcc tcttaaattc agctagttat
      421 ctgaacgaag ggataattac taaaaagatg aatccttttg ttcgtcaaac aattgaaata
      481 atacgtgaga atgcgtatca aaaattatct gttaaagata ttgctgtcag tctatcgata
      541 cacgaaaatt atttatcacg attgtttaag aatgatatgg gaatatcaat aaaagagtat
      601 attagtgaaa tcaaaatttc tattgcaaac gatctgttat catcaactga atattcaatc
      661 cagcaaatca gtgacaagat aggattctca acagtacaat ctttttctaa agcctttaag
      721 aaagcaaatg gtgtttcacc gggagtatat cgaaaacgta gattaggtct aggaatcatt
      781 aatggtgaat aaactaaaca tttgattttg ataaatattc gttactttaa acgcttacta
      841 tttatgtgag cgttttttat aatgcaataa agaaacggag gagagcttat gtataaggat
      901 aatgaaatga atattattta tcgatcagaa aaccaacaat ttcatttgtt taatcaggag
      961 ataagttaca tttttaagat atcggaagat ggtaaattat tgcatttata ttatggtgag
     1021 aacttaccag ataatgacta tagtcatcta attgagatgc atcatcggcc tatgacaacc
     1081 tatagaaatg aaaacgattt gctatattcg ttagagcact taaaacaaga atttcctgaa
     1141 tatggtacaa cagattttag acatcctgct atttcattac tacagaaaaa tggctctcgc
     1201 ttatcagatt ttgtctatca agggtacgaa gtggaagaag gaaaacctaa actagaaggt
     1261 ttacctgcta cctatgttga taataatgat gaaagcaaaa cattgaaagt ttatatttta
     1321 gattcagtta caaatgttca agtagaatta ttatatacaa tttatagaga ttatcctgtt
     1381 attactcgta gcgcgcgagt tatgaataaa ggaaaagata ttcaaataat cgagaatatt
     1441 agcagtttat cattggattt acccgatgca aattatgaat ggcaacaatt atctggtgct
     1501 tggggtagag aaagaactat taagtcgcgt actttacaac aaggaattca atcaatcgaa
     1561 tctactcgag gtatttcaag ccatcagcat aacccatttg ttactttaaa aagaaaaaat
     1621 actgatgaaa atcaaggaga agctattggt gcagcactag tttactcagg aaacttctta
     1681 attcaagcag aagtagatac atgggatgtt actagactac aagttggcat caatccattt
     1741 ggatttaatt ggaaactcaa tccaggagaa atatttacag caccagaagc gattctggtt
     1801 tattcaagta agggtttaaa tgccatgagt caaacttttc atcaactatt tagaaaacgc
     1861 ttagctcgtg gtaagtggcg agaaaaagac cgtcctgtct taattaataa ttgggaagca
     1921 acatattttg attttgacga agaaaagttg gtaaatattg ctaaaaaagc atttgatgtt
     1981 ggtattgaat tatttgtatt agatgatggc tggtttggag aaagagaaaa cgattgtgca
     2041 ggattaggag attggcatgt aaatcctaaa agactaccta gaggaatcgg cagcctttca
     2101 gaaaaaattc gtagttttgg tatgaaattt ggtttatggt ttgaacctga aatggtgaat
     2161 aaggatagtg agttatatcg cacacatccg aattggatta tttctacacc taatcgaaaa
     2221 cctaatcatg gtaggaacca atatgtatta aattttgggt tagatgaggt tgttgaaaat
     2281 attttcgatc aaatgtgtaa aatcattgat gaatcaaact tagattacat taagtgggat
     2341 atgaatcgtc cattgactga tgtatttgac agtcacttgt cagcagatca acaaggagaa
     2401 gtattccaca gatatgtact aggcgtatat cgcttatatg aaaaacttat aacaaaatat
     2461 cctaacatac tatttgagtc ttgttcatca ggtggtgggc gctttgatcc tggaatgctt
     2521 cactatgcac ctcaagcttg ggctagtgat gattcagatg caattgaaag gttaaaaatt
     2581 caatatggaa ctagtatgct gtatcctctt tcgtctattg gtgctcatgt atcaattgtt
     2641 ccaaatcatc aaacaaaccg tataacacct ataaaaacta gaggaaatgt agcttttttt
     2701 ggtgcatttg gatatgagct tgacttaaat gaattaagtg aaggcgattt gaggattgta
     2761 aaagaacaaa ttgcctttta taaaaaatat agaaccataa ttcataatgg tactttttat
     2821 agactattat caccattcga tgatgataat caaaccgcgt ggatggttgt tagtcatgat
     2881 aagaaaacgg ctattgttgc tcattataaa acattaaatg aggtaaatgc tccttaccgc
     2941 cgactgaaat taaaagggtt agataatgac ggactttata atgtaggaca aaatagtttg
     3001 cgatctggaa tggaattgat gagagcagga ctagtctgtt cagatgcatc tagtggacaa
     3061 ataaatgatc agaatcgacg cccagaaaca tttgattttg attccaagat ttgggttata
     3121 acacaggagg aaaagtagag atgaataacc aaaaaagctt acttcaaaaa ggagcaatct
     3181 taagtatttc actaatgtta acaagctctc aagcaattaa tggtgttatt ccacaaatga
     3241 aacagtcttt ggggatatca caaagtcaaa gtgaactttt aggaactgca ccaagtataa
     3301 ctgttatttt gtttatctta ttatctagtt actttgccaa aagaatagga atgaaaaaga
     3361 caataatttt aggtttatta ttagctggta taggaggaat tattccagta tttacagcta
     3421 ccttccaaac cgttcttatt agtcgagtaa tattaggtgc cggtttagga gtatataatt
     3481 cattggctgt gacatatatc agctctttat actctggcaa tactagagca acgctattag
     3541 gtattagaaa ttcaatggaa gctttaggtc agacaatcct tatttttctt gctggagttt
     3601 tagtgaacat taattggacg gcttcgtttt tagtctatgc aattgcgttt cctgtagctc
     3661 tcttattcgc gctaaaagtt cctgaaatta gagatgaaaa tagtgacata cctgaaaatc
     3721 atgtaaaaga aaagatgaat ccaatggttt ttgccctagt tctatttgca atcttactcg
     3781 taatgaatag tattgctatt tctgtacgat ttgcatcaat tgcaactgaa attaaagggg
     3841 taaactttaa tgctagtaac tatttagctc taatgcctat cttaggaata ctagcaggat
     3901 ttatgtttgg accaataaat aagtggatag gaaaaggaac cctatacttg ggaattatat
     3961 tctttataat ttcaaatttg ttaattgctg tgtcaaacgg taatatgacg ttcctgctaa
     4021 cgggtttatt tttatcaagt ataacaggat catggtgctt cccatttatc tttagtaact
     4081 tagataaagt cactacaaag aatacaatta attttgctac ttcattgatt tttattggct
     4141 gtaatattgg taattttata gctcctattg ctatgcaatt agcacaattt ctaacaagaa
     4201 gtacaaattt gactgctcca ttttttgtat tcgcaggaat atttattgtg atcctatttg
     4261 taacattttt tgcgacaaat aaaaaaaata ctagagtaac ccgtggtgct agttaatttt
     4321 aatatcctaa agaatatctc aaagttcctt caaaacgtcg ttgtgctcg
//
LOCUS       DADLIO010000131         4305 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.139, whole genome shotgun sequence.
ACCESSION   DADLIO010000131 DADLIO010000000
VERSION     DADLIO010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4305
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.139"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            148..1137
                     /locus_tag="JOX41_002772"
     CDS             148..1137
                     /locus_tag="JOX41_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HAY6450452.1"
                     /translation="MKKKKQDLINGTFREKKKNLKKVVAFSDNRISPKMRELMTGCGS
                     YLEFIATIDKEKKKLVQAHFCKNRFCPLCAWRKARKDSMMLSIMMQAIAEEKQYQFIF
                     MTLTTPNVKAECLNDEIDLFNHALKKMFMRKRVKTSIKGYVRKLEITYNKKRNDYNPH
                     FHLILAVNKSYFTDKDYYIKQSEWLDLWREVTGKTGINPDGTDEITQLDIRKVKGFQQ
                     EKAVQEVAKYSAKDFELTESQEVFDTFYHAMKGRQLITFNGVFKEYKKKYESGDLDRY
                     KKKDENEYFWFLTASWMRKESKYAVDYREMSADERNYFSGMYVDEKSVEGENE"
     gene            1134..1553
                     /locus_tag="JOX41_002773"
     CDS             1134..1553
                     /locus_tag="JOX41_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450453.1"
                     /translation="MTDSTDKMTIKALADELGITKNTVRNYLVKAGYDLARYKKNGII
                     LLDKELIGVARSIYRSKGGQLTGHLPVNSTGSDFPLEKENEFLRDQLAEKDKHISELT
                     EMIRDQQKLTLLQQQKNDQLLLENQELKNRKWWQFWK"
     gene            1562..1870
                     /locus_tag="JOX41_002774"
     CDS             1562..1870
                     /locus_tag="JOX41_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450454.1"
                     /translation="MDKIDLREETVNRIEVMYERLADYLNLSDEDNYSEMLERMMDVL
                     NSVINADLAKSSVLTNEFVHKHLAQTTDEAEKEFWLKLMSHIMQLNQISVINSKEKGM
                     "
     gene            1874..2236
                     /locus_tag="JOX41_002775"
     CDS             1874..2236
                     /locus_tag="JOX41_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450455.1"
                     /translation="MGMTLADIKVQEEKLKKEQAKLRQQKKRLIEKENAAMGKALRKR
                     FGFESFADFERWLSSISDDQQHEKSVGNELRADEKSAPSERNYPNESDGIFGGIPNRK
                     SQMSESGFASMFSDVNSR"
     gene            2458..3864
                     /locus_tag="JOX41_002776"
     CDS             2458..3864
                     /locus_tag="JOX41_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HAY6450456.1"
                     /translation="MGFSISFKKGTKNTSISHNNRELTDSQKINDWHKHIDFTKSDEN
                     IYLEQINIREKYEELFGEAVEKYNAKQKRADRKIEDYLAKVRKDKKMEPQREFIVQIG
                     TLDDFRTTRDDGSSTGISEQQAEQNRVIANKILVEYFKEFKERNPSLSVYNAVIHNDE
                     VSPHLHLNIVPVAEGYKRGVQKQPSFNKALQQQGLRADKENGRVIWNNFRNQEVESIE
                     RLMADFGWERELVGTNKIKDIHEYKEIMSEISELRQTAVKERESVSDELRYICRQREE
                     NEREKALVASERAKIEEEKKNMLNVKKEMAVIFQKDMVPLESFKRLPDGSYHLSGNDF
                     VDLYQRATRATNAKRNADNMSEQYLQMLEQNTELNEYVAALEEERHLSGRKQLADLQV
                     ENKKLKEENRSLRQRLERLKNAFQKSITRLSIRFGLAEKDMGLSEELEVLEQEKTLFY
                     RQNVSQHKLERSEDEIEW"
BASE COUNT         1497 a          602 c          996 g         1210 t
ORIGIN      
        1 aaaaaaaaag attgcttttt cttccctagt attttatagt tttaattgac tagaaaaaaa
       61 ctaaactaga aaggagagca atctattttt tgttatcggc ttttcagcct tttttgtata
      121 caaaatttgt agattcagta tagcaagatg aaaaagaaaa agcaagattt gattaacgga
      181 acatttcgag aaaaaaagaa aaatttgaaa aaagtggtgg catttagtga taatcgaatt
      241 tctcccaaaa tgcgtgaatt gatgacaggc tgtggttcat atttagaatt tattgcaacg
      301 attgataagg agaaaaagaa attggtccaa gctcactttt gtaaaaatcg tttctgtccg
      361 ttatgtgctt ggcgtaaagc tcgtaaggat tcgatgatgt tgtcgattat gatgcaagct
      421 attgcggaag aaaagcagta tcaatttatt tttatgacgt tgacgacacc gaatgtaaaa
      481 gcggaatgtt tgaacgatga aattgatttg tttaatcatg cattgaaaaa gatgtttatg
      541 cgcaaacggg ttaagacttc gattaaaggc tatgtgcgaa aattggaaat cacgtacaac
      601 aaaaaacgga atgactataa cccgcatttt cacttgattt tggcagtaaa taaatcttat
      661 ttcacggata aagattatta tatcaagcaa tcggaatggt tagatttgtg gcgggaagtg
      721 accggaaaaa cgggaattaa tccggatggt accgacgaaa ttacccagtt ggatattcgc
      781 aaggtcaaag ggttccaaca agaaaaagca gtacaggaag ttgcgaaata ttcggcaaaa
      841 gattttgaac tgaccgaaag tcaggaagtg tttgacacat tctatcatgc aatgaaaggt
      901 cgtcagttga ttacgtttaa cggtgtattc aaagaataca agaaaaaata tgagtcgggt
      961 gaccttgatc gttataagaa aaaagatgag aatgaatatt tttggttttt gactgcttcg
     1021 tggatgagga aagaatcgaa atatgcggtt gattatcgtg agatgagtgc tgatgaaaga
     1081 aattattttt caggaatgta tgtcgatgaa aaatctgttg agggggaaaa tgaatgactg
     1141 attcaacgga taaaatgaca attaaggcgc ttgctgatga actaggaata accaaaaata
     1201 cagtgagaaa ttatctagtc aaagccggat atgatcttgc tcggtacaag aaaaatggaa
     1261 ttatcttgct agacaaagag ttgattggtg ttgctcggtc aatttatcgg tcaaaaggtg
     1321 gtcaattgac tggtcattta ccggtcaata gcacgggcag tgattttcct ttggaaaaag
     1381 agaatgagtt tttgcgtgat caattagctg agaaggacaa acatatttct gaattaacag
     1441 aaatgattcg tgatcaacaa aaattgaccc tgcttcagca acaaaaaaac gatcagttgt
     1501 tactagaaaa tcaagaatta aaaaatcgaa aatggtggca attctggaag tgagatgtga
     1561 catggataaa attgatttga gagaagaaac agtcaataga attgaagtga tgtatgaacg
     1621 gttagctgat tatttgaatc tttcggatga agataattat agtgagatgc ttgaacgaat
     1681 gatggatgtt ctcaactcgg ttatcaatgc tgatctagca aaatcttcag ttttgactaa
     1741 tgaatttgtt cataagcatt tagcgcaaac aactgatgaa gctgaaaaag aattttggtt
     1801 gaaattaatg agtcatatta tgcagttaaa ccaaatttcc gttattaatt ccaaagaaaa
     1861 ggggatgtag tttatgggaa tgactttagc agatattaaa gtgcaagaag aaaaattaaa
     1921 aaaagaacag gcgaaacttc gccaacagaa gaaacgattg attgagaaag aaaatgctgc
     1981 aatgggcaag gctcttcgca agcgttttgg gtttgaatct tttgctgatt ttgagcggtg
     2041 gctatcgtcg atttctgacg atcagcaaca cgaaaaatca gtgggtaatg agttgcgagc
     2101 tgatgaaaaa tcagcaccaa gcgaacggaa ttaccctaac gaatctgacg gaatattcgg
     2161 agggataccg aatagaaaaa gtcagatgag tgagagtgga tttgcgtcaa tgtttagtga
     2221 cgtaaattca cgataagcga atattttgca tgaagcaaaa taaagcgtaa aaggagttga
     2281 gagcgtgaca cgctttcggc tccttttttc gttgtcactt gtgacggcga aaaccctcgg
     2341 agagcgtttg gaattgtgac agtcatgtca caattaggaa aacgttactc tttgacaaag
     2401 agtaacagaa aggtttacac tctttttatt agcgacagcg cgaaggaggg gtttaacttg
     2461 gggtttagta tttcgttcaa aaagggaaca aagaatacaa gcatttctca taataatcgt
     2521 gagttaactg atagccaaaa aatcaatgac tggcataagc atattgattt cacaaaatcg
     2581 gatgaaaata tctatttgga acaaataaat attcgtgaaa aatatgaaga attattcggt
     2641 gaagccgtag aaaaatataa tgcaaagcag aaaagagccg atagaaaaat tgaggactat
     2701 ttagcaaagg ttcgcaagga taaaaaaatg gaaccacagc gagaatttat cgtgcaaatt
     2761 ggtactcttg atgattttcg tactactcgt gatgatggtt cttctactgg catatcggaa
     2821 caacaagcag aacaaaatcg agtgattgcc aacaaaattt tagttgagta tttcaaagaa
     2881 tttaaagaac ggaatcctag tttatccgtc tacaatgctg ttattcataa tgacgaagta
     2941 agtccgcacc tgcatttgaa tattgttcct gttgctgaag ggtataaacg gggtgttcaa
     3001 aagcaaccaa gttttaacaa agccttgcaa cagcagggtt tacgagcaga taaagagaat
     3061 ggtcgagtga tttggaataa ttttaggaat caggaagttg agtcaattga acgtttgatg
     3121 gcagattttg gttgggagcg tgagttagtc ggtactaaca aaatcaaaga tattcatgaa
     3181 tacaaagaaa tcatgagcga aatttccgaa ttgcgtcaaa cggccgtaaa agagcgtgag
     3241 agcgtttctg atgagttgag gtatatttgt aggcaaagag aagaaaacga gcgtgagaag
     3301 gctctggtgg cttctgagag agcgaagatt gaagaagaga agaaaaatat gctgaatgta
     3361 aaaaaagaga tggcggtcat tttccaaaaa gatatggttc ctttagaaag tttcaagagg
     3421 cttcctgatg gttcgtatca tttatctggg aatgattttg ttgatttgta tcaacgagct
     3481 acgagagcaa caaatgccaa gagaaatgct gataacatga gtgagcaata tttacagatg
     3541 cttgagcaaa atacagaatt aaatgagtat gtagctgcat tggaagaaga gcgtcatttg
     3601 tctggtagaa aacaattagc agatttacaa gtggaaaata aaaagctgaa agaagaaaat
     3661 cgctctttac gccagcgttt agagcgatta aaaaacgcat ttcaaaaatc gatcactcgt
     3721 ttgtctatcc gttttgggct tgcagaaaag gatatggggc tttctgagga attagaagta
     3781 ttagagcagg agaaaacctt attttatcgt caaaacgtct cacagcataa attagagcgt
     3841 tctgaagatg agatcgagtg gtagttacga tgtgcagtca acggtaccgg aggcggtttg
     3901 tgccgaggat aaggagttga cggctaaacc actagcctat taagctgaca tttgctaaaa
     3961 aatggcaagt ccattttttg gccaacttag cgttagcgaa gtttgggggc gcccttttta
     4021 aagggtgcgg ttttatgttt gcatgactaa gaatgagtgg gaaaatttaa cagccctatc
     4081 taacaggcgg ttaaatgtac aaaatatgta caccccctta aaaatgcagt ggtcgattga
     4141 tcgaatttta tgtctttggg ttttggggtt ttaaaacgaa aaaaaggggg cgattttcgc
     4201 cctctttttt gatgtttttt cttatcttga tactataggc aactatttct gcgaagaaat
     4261 cggggctata gtatgggtct atcccttgtg gctctaagga agaac
//
LOCUS       DADLIO010000132         4291 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.140, whole genome shotgun sequence.
ACCESSION   DADLIO010000132 DADLIO010000000
VERSION     DADLIO010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4291
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.140"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            83..697
                     /locus_tag="JOX41_002777"
     CDS             83..697
                     /locus_tag="JOX41_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAY6450457.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(862..1686)
                     /locus_tag="JOX41_002778"
     CDS             complement(862..1686)
                     /locus_tag="JOX41_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450458.1"
                     /translation="MIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLELK
                     TLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITACE
                     IGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEKRN
                     KLVHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNKSQ
                     ITLSKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD"
     gene            complement(2324..2581)
                     /locus_tag="JOX41_002779"
     CDS             complement(2324..2581)
                     /locus_tag="JOX41_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAY6450459.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(2574..2843)
                     /locus_tag="JOX41_002780"
     CDS             complement(2574..2843)
                     /locus_tag="JOX41_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAY6450460.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(2974..3153)
                     /locus_tag="JOX41_002781"
     CDS             complement(2974..3153)
                     /locus_tag="JOX41_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450461.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            complement(3534..4241)
                     /locus_tag="JOX41_002782"
     CDS             complement(3534..4241)
                     /locus_tag="JOX41_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450462.1"
                     /translation="MNKVVYQLTTEDVSQFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYMESETSQTKVTVSHNRLDVYKRRPDTLKKGAELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATVDDYYLVFTRFLT
                     CGTESIVLMGMDYELTVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKGQ"
BASE COUNT         1337 a          802 c          601 g         1551 t
ORIGIN      
        1 atttaaaaag aaaagtgaca tatggcttcc tcgtgtatga ttagggtgta ttttaaatag
       61 ttgcagaaag taggtaaaag ttttgagagt tgcatacata cgtgtctcat cgatcgatca
      121 aaatgaacaa cgccagattg aagaaatgaa aaaattcggt gcagagagaa ttttcatcga
      181 gaaacaatct ggcgcaacga ttactcatcg acctgttttc caagaagcat tagattacgt
      241 ccgagatcaa gatattttta ttgtggaagc tattgatcga cttggaagaa attatgacga
      301 gatcatcgct tcagtcaatt acttgaagaa gaaaaatgtg aagctgatca ttactagttt
      361 accgatcatg gctgaagcaa ttggcaatcc tctcctggat aaattcatta aggatctgat
      421 catccaaatt ttggccatga tcgctgaaca agaacggact gaatcgaaac gtcgccaggc
      481 acaaggaatt aagatcgcaa aagcaaacgg cgtctacaaa gggcggccca aattatacag
      541 tgcagacgca aaagatcccc aacgtcgcct tgtttacaaa agcatcgttg aagatcttaa
      601 aaatggtgtt gcgattgcta agattgctaa agactacaat gttacgagac aaaccgtgta
      661 tagaataaaa aaagacagca tggtcaatga caaatagttg atcatgctgc ttttattatc
      721 ttctcatctt taatttccta catataatta ctatctataa aattaagtct tactcagaac
      781 agataaagca taaaattcca acaaaccatt ttttacttaa ctaaataaag agtctgttaa
      841 tataatcttc acttatttac gttaatcccc tactgtattt gttggttcct tatctatatt
      901 ttctacaaaa tccttattat cttgtgattt agcttcgtat aattctttgt atgtcgacac
      961 attggttata ctaattccta tagctagttc ttgagactct acttttctct ctagctcctt
     1021 tgacaaagtg atttgagatt tatttggttc cgttggagtc aattctatag attcttcata
     1081 aaaatctcta tacataaagc tatcattaat tttataaaaa aaattaaatg tttttagcac
     1141 tgccatataa cattcaaaac attcttctat agttggttta cttccttgag gagaatgaac
     1201 caatttatta cgtttttcta tgaaattttt aatttccttt cttatttctt tcggaaactc
     1261 aatattaaag taccctttaa acatgctccc taataatttg tctacagggg gagattgtaa
     1321 attctcaaat attagagtta aatcaggttt ctcttgttga taaaattcct ttacccctat
     1381 ttcacaggct gtaattatcg aaataaacct atctctagta tttgatatat ttttacttct
     1441 tttaaggagt ataagagaaa aggggatact ttcgtgtcca tgcatgtaat taactaattg
     1501 ttgagcttca gaagttatat ctctaattat atagttaacg gaattaggaa gtgtctttaa
     1561 ctctaatgaa atttctatcc aattactatc ttctaatctg tatatgctcg aagtataatt
     1621 tgattcgtca gcaagcatcg ctacatccca aacactgatc ataaaatctt ttaaacgttc
     1681 aatcatttca gcaatattgc taaaatcagc taatttttct ttagaataaa aaaaaacatt
     1741 tatatcagaa tcaataaatt ctattttttt attactatat cgtcatcatt atcttgacca
     1801 tttatgttta ttgttccctg agtggggagt acttctttca aattcaagtt aaatttatat
     1861 tccattactt ctcctccaat atataaaaat tacttaactg tatccaaatt taatatgtaa
     1921 ataaatcatt aatttttagc taaattctat gagaagttta tttttgttgt ttttgctaat
     1981 taactaaaac tagtacaaaa aatttaaaat agattattaa acctattgct tattctattc
     2041 agtcatatat ataagcgtca tcctttagta actaacatcc cacactacaa tagtattata
     2101 acatatctat tcaacttcaa attgttgaaa tttaagccat ttatatttac ttttcctcaa
     2161 ctttagaaat gattttacta accttatatc cgtaatacgc gtaacaaaca cattcattaa
     2221 taacaatcaa cactaagcta tattagcttt ttaaatgact agggtaaata aaataaggat
     2281 caaaaacttt taagtttctg accctttcct tacttccgat tggttaatag tgatcttttg
     2341 cagaataaat aaatatcgtt tcattttcaa ctctatatat cagtctatgt tcatctgtaa
     2401 ttcttctgga ccattttcca gataaatcat gctttaatgg ctcaggtttt cctaatccag
     2461 caaaggggga acgatcgata tcttttatta acttgttaat cttttttata ttgcttttgt
     2521 ttccttgctc atgccaataa agataatcat cccaagcatc atcagaccaa gccttaatca
     2581 tcagattcaa cctcgattaa gtcatgtgtt ttaaatgcac ctttggagaa ttgttcatct
     2641 cctcgacgaa ttttttccat gacgtaatta ttagaaagtg ttctcaacgt ttcttgcata
     2701 gaatcataat ctctttttga taatacaaca actgtatctt ctacatcttt acttgttaca
     2761 ataagtgttt cagcatcctc attaacttgt ttcatataac tacgtaaatt ttggcggaaa
     2821 tttgaataag ctactgcttc cattcctttc accccttatt tatttctata aaacaattgt
     2881 acattatatt gtacaattaa gcaaatgatt aatattctaa cttcttataa ttaaaagtgc
     2941 tatcactttt agtttttagg ataaaaagtg acgtcacttt ttgagtgctg gtacctcaaa
     3001 tcctgctttt tcttgggcaa tcaataaatc taacgcaata cacataatcc tggattcact
     3061 tttgccgtac ttctgcttta gttgctgcaa ttctttttgt ctcttttcat ccaacgtcac
     3121 gggtaaccgt ttatttccta ttgcaattgg cattagtact ctctcctttc atcgaaataa
     3181 ccctattaaa aatatggctg caatcaactt gaatattaga ctcacaaggg ttaacacaaa
     3241 gcgccaaaag atcaaacaaa ataccagtat tcctaagaat actacgaagt ttaaatgtag
     3301 agctgcacca tgacgcataa gtatctcgcc aacaaacagt acgaacaata gaggaatgat
     3361 tttattcata tggatctcct tctttctctt aggttatcgg gctttgcccg cttatttcgc
     3421 accacctaag cggcgggggc ggttggatcg attggtgcga aataagaacc attcccttaa
     3481 tttcaaggtt ttttgttctt atttcacaca tcctcacttt tcggtataaa tggttattga
     3541 ccttttttcc tttcaaatcg ttgatatggc attcgtttac ggtcaagttc attttggatt
     3601 tcttctgtat cgtcgtaagt gtaggtgtct aaaaaatcag ttaaagtcgt gtaccagtcg
     3661 tcgcctgggt tatctacttc ttctacatat tccctcaaaa atgcttcggg tacagtgagt
     3721 tcataatcca ttcccattaa cacgatagat tccgtcccac acgtcaaaaa tctagtaaat
     3781 acaaggtaat aatcgtctac cgtcgcatct ttgctgttta gctcttccat ttcttcttcc
     3841 attaattcca tgctctcaaa aattgaataa tattctgatt ctgagtaata gtgtttcctg
     3901 caaatcgtgt agctgacaaa gttttcgacc agctcactcc tttctaggta aacattcatg
     3961 atatattttt ctgtttctag tcgtagaagc tccgctcctt tttttaatgt gtcaggacga
     4021 cgtttataca cgtctaaacg attatggctg actgtaacct tcgtttgact cgtttcactt
     4081 tccatataca actgttcttc cactctttga ataaagtact tcatttcttc catacaacta
     4141 aagtcttttt gaatccgtct gattacttca ttcaagtgtt ctttgtttgt taaaaattgc
     4201 gaaacatctt ctgttgttag ctgataaacc accttattca ttatctttct cctccgattc
     4261 aatcgtataa aatgcaccat ttttttcgat a
//
LOCUS       DADLIO010000133         4282 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.141, whole genome shotgun sequence.
ACCESSION   DADLIO010000133 DADLIO010000000
VERSION     DADLIO010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4282
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.141"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(37..1257)
                     /locus_tag="JOX41_002783"
     CDS             complement(37..1257)
                     /locus_tag="JOX41_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAY6450463.1"
                     /translation="MKLIGIVGSAAELSYNRKLLTFIQKQYHELFNLEIIEIKDLPLF
                     NQDDDQTNSPAIQQLNRKILMADGVIIATPEHNHTVPAGLKSALEWLSFKIHPLENKP
                     VMVVGASYYDQGTSRAQLHLRQILDAPGVNALVMPGNEFLLGKAKEAFDQEDRLIDPR
                     TVDFLGSTLASFVKFIKVVSTLAGPKKLPPEDLHATGTIATTIPDVDMSDDHWLEKAS
                     EAVGAVSGNTYVKLNRGLLTVDQINYFLDSMPMELTFADNNNQFLYYNLRQEAKEMLA
                     ARVPGQVGNPLANCHPEKSYKNVEWVIQQLRSGATDAVRVHVPKQVPEKYIVHNYQAM
                     HDENGEYAGINEYILDFKPIIEWYLQQTGQQLVGNEDAVSSASVHGGKTDAVTSASTH
                     DETAVDAVSSASVK"
     gene            complement(1277..1882)
                     /locus_tag="JOX41_002784"
     CDS             complement(1277..1882)
                     /locus_tag="JOX41_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005234653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAY6450464.1"
                     /translation="MKFIGLVGTNSTRSTNRELLQFMKNYFVNEAEIEIVEIKELPLF
                     NKPENTELPNVVKEIAGKIEQADGVIISTPEYDHAVPASLINALNWLSYGIFPFVDKP
                     VMITGASYGTLGSSRAQAHLRQILDSPELKARIMPSSEFLLGHSLQAFDEQGRLIDEE
                     QVAKLRELFKDFLLFVTITSQLQHAHQANKREAESFSWETI"
     gene            complement(1931..2863)
                     /locus_tag="JOX41_002785"
     CDS             complement(1931..2863)
                     /locus_tag="JOX41_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HAY6450465.1"
                     /translation="MNQVIEETKIWQMMGTTITLQVGHEEPSRLLAELGEWLHVYEHR
                     FSAHDATSELMAINQAAGRQAVIVHPELFELIKLGKAHSCARNSYLNIAIGPVVQKWH
                     IGFEDALVPTKAEITELLLLTDPHQIQLDEKMKTVFLTKPGMMIDLGALAKGYIADKL
                     ITHCRERNAAFALVNLGGNIVVFGESPRRSDGAWRIGLRNPKGSREESLAVVKLNNQS
                     LVTSGIYERYLQNGSSVYHHIIDPKTGFPVKNDVASLTILSDSSVDGEIWTTRLFGAS
                     SLEVLKALEEQPGIEGAVVTKENQFLYTKGFEKI"
     gene            complement(3284..4144)
                     /locus_tag="JOX41_002786"
     CDS             complement(3284..4144)
                     /locus_tag="JOX41_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAY6450466.1"
                     /translation="MNIEKFITARKAANLSQKEVSEGICTQATLSKFENNGQVPSLKI
                     LIKLCNRINLPLVELFSSMNVINTQLDEQLEKAEFSLITSEYEQLTQILAAIDPKVID
                     ESELIARYYYLKGFEMIFTNAPITDVLFHFDQLLMAETANTLFRLLAYTGIGMVYARE
                     KELEKAEVYFNRVFEKIYTYPIRTTEDIWRVLNIVFHCGVFFAQDGDLETSDALLNYA
                     IDICSDNHLTYYLARAAAQLAKNAQAKNKSKAEVLELIQDALAFAKINKNKKLIDELN
                     HMKKMILLIN"
BASE COUNT         1219 a          861 c          701 g         1501 t
ORIGIN      
        1 tttattcttt atttaaaact ttgcaacaga acctttttat tttacagaag cactcgaaac
       61 tgcatctact gcagtttcat cgtgtgtgct ggcgctggtt actgcatctg tttttccacc
      121 atgaacagat gcacttgaaa ccgcatcttc atttccaaca agttgttgac ccgtttgttg
      181 taaataccac tcaatgattg gtttgaaatc aagaatgtat tcattgattc cagcatactc
      241 tccattttca tcatgcattg cttggtaatt atgcacaata tatttttctg gcacttgttt
      301 tggtacatga acacgtaccg catctgttgc tccgcttcgc agttgttgaa ttacccactc
      361 tacattttta tacgattttt ctgggtgaca gttggctaat ggattcccta cctgaccggg
      421 cacacgagca gctaacatct ctttcgcttc ttggcgcaaa ttataatata aaaattggtt
      481 attattatct gcaaaagtta attccatcgg catcgaatct aaaaagtaat tgatttgatc
      541 cactgtcaat aacccacgat ttaatttgac gtaagtattt ccagaaacgg caccgactgc
      601 ttcagaagct ttttccaacc aatgatcatc tgacatatca acatcgggta ttgtcgtagc
      661 aattgttcct gtcgcatgca aatcttctgg tggaagcttt ttaggccctg ctaaggtaga
      721 cacgacttta atgaatttta caaaacttgc taatgtactg cctaaaaagt caacagttcg
      781 tggatcaatc aagcgatctt cttggtcaaa tgcttctttt gcttttccca ataaaaattc
      841 atttccgggc atcactaatg cattcacgcc tggtgcgtcc aaaatttggc gcaagtgtaa
      901 ttgcgcgcgt gaagttcctt gatcgtagta agaagcaccc acaaccatta caggtttatt
      961 ttcaagtgga tggattttaa atgatagcca ttcaagtgca cttttcaatc ctgctggaac
     1021 cgtatgattg tgttctggcg tagcaataat taccccatca gccattaaga ttttgcgatt
     1081 tagctgttga atagcaggac tatttgtttg atcatcatct tgattgaaca gaggtaaatc
     1141 tttgatttca atgatttcta aattaaatag ttcatgatat tgtttttgga taaatgttaa
     1201 taatttacgg ttatatgaaa gttcagctgc tgatccgacg atacctatta atttcatctt
     1261 tgtttgctcc cctcgattaa atcgtttccc atgaaaagct ttcggcttca cgtttatttg
     1321 cttggtgcgc atgttgcaat tgactagtga ttgtgacaaa gagtaagaaa tctttgaata
     1381 gttcacgtaa ttttgcgact tgttcttcat caatgagtcg tccttgctca tcaaaggctt
     1441 ggagtgaatg acccaataaa aattctgagc ttggcataat tcgtgccttt aactctggtg
     1501 aatccaatat ttggcgcaaa tgtgcttgtg cgcgtgaaga acctaacgtg ccataagacg
     1561 ctccggtaat catcactggt ttatccacaa acggaaaaat accatatgaa agccaattta
     1621 atgcgttaat caatgaagca ggaaccgcat ggtcatactc tggtgtgctg atgattacgc
     1681 catctgcttg ttcaattttt ccagcaattt ctttaacaac atttggtagt tctgtgtttt
     1741 caggtttgtt aaatagtggc agctccttga tttcgacaat ttcgatttct gcctcattta
     1801 caaaataatt tttcataaac tgtaataatt cacggtttgt tgaccgcgtt gaatttgttc
     1861 ctactaatcc aataaatttc atcttcattc tctttccttt ctaacatcga tttctgactg
     1921 ttcgcacgta ctaaattttt tcaaatcctt ttgtatacaa gaattgattc tcttttgtta
     1981 caactgctcc ctcgataccc ggctgttctt caagcgcttt caacacttct aaagaagatg
     2041 ctccaaataa acgtgtagtc cagatttctc catctacaga agaatcagac aaaatcgtca
     2101 ggcttgctac gtcattttta actggaaagc cagttttcgg atcaatgatg tgatgataca
     2161 ctgacgaacc attttgtaga taacgttcgt agattccaga ggtaactaaa gattggttgt
     2221 ttagtttaac caccgcaagc gactcttcac gtgaaccttt aggatttcgc aaaccaatac
     2281 gccaagcacc atccgaacgt cttggtgatt caccaaaaac aacgatattt cctcctaagt
     2341 taactaaagc aaacgctgca tttcgctctc ggcaatgtgt aattaattta tctgcaatgt
     2401 aaccttttgc taacgccccc aagtcaatca tcattcctgg tttggttaaa aaaacggttt
     2461 tcattttttc atctaattga atttggtgtg gatccgttag cagaagtaac tcagttatct
     2521 ctgcttttgt tggaaccaat gcatcttcaa atccaatgtg ccatttttgt acaaccggac
     2581 caatagcaat attcagataa ctatttcttg cacaactatg tgcttttcct aatttgatga
     2641 gctcaaaaag ttcaggatgt acaatcacag cttgtcgtcc agcagcttga ttgatggcca
     2701 ttaattcaga agttgcatca tgtgcgctga agcgatgttc ataaacgtgc aaccattcgc
     2761 ctaactctgc tagtaatcga ctaggctctt catgcccaac ttgtaatgta attgttgtcc
     2821 ccatcatttg ccagattttc gtttcttcga tcacctgatt cattttgtac cttctttact
     2881 tgaactacgg attacatgag taattagttt ttatttttgt tactgttttc acaaccagat
     2941 gatacgcctg ctagatttat ttgtcaaccg attttatata tttttttata taataaggta
     3001 attttaatat aaaattttat attgtaaaaa aacaaataag ggaaacaaac aacacatttt
     3061 tgtgtgttgc ttatttccct ctaactatcg ttttctattt gatggttaac ctacttaaaa
     3121 taaatactgc aacgacaaac ggagatcaag catgctttgt aacgtatttt acgataatta
     3181 cgactttatt ttattactct atcttgctgc catacccgtc tatccctaat catctttggt
     3241 gaattttttc aaagttagca taacaaaaat aagtattttt tccttagtta atcaatagta
     3301 tcattttttt catatgattt aattcatcaa ttaatttttt gtttttatta attttagcaa
     3361 aagctagtgc atcttgaatc aattcgagca cttctgcctt cgacttattt ttagcctgtg
     3421 cgttcttcgc taattgggca gcagctcgtg ctaagtaata agtcaaatgg ttatccgaac
     3481 aaatatcgat tgcgtaattt agtagtgcat cacttgtttc caaatcaccg tcttgcgcaa
     3541 aaaaaacacc acaatgaaag acgatattta acacccgcca gatatcttct gttgtacgaa
     3601 tcggatacgt ataaattttt tcaaacactc gattgaaata aacttctgct ttttccaact
     3661 ctttttctct agcatagacc attccaatac ctgtatatgc caataaacga aacaacgtgt
     3721 tggctgtttc tgccatcaac aactgatcaa aatggaacaa cacatccgta attggtgcat
     3781 tcgtaaaaat catttcaaat ccttttagat agtagtaacg tgcaatcagc tcagactcgt
     3841 caattacctt gggatcaatg gctgctaaaa tctgtgtcaa ttgttcatat tcactcgtaa
     3901 tcagtgaaaa ctctgctttt tctagctgtt catcaagttg tgtattgatc acgttcatcg
     3961 aagaaaaaag ttcaactaac ggaagattga ttcgattaca taatttgatt aaaattttta
     4021 acgaagggac ttgaccattg ttctcaaatt tacttaatgt tgcttgtgta caaattcctt
     4081 cagacacttc tttttgagat aagttggcag cctttcttgc cgtaataaat ttttcaatgt
     4141 tcattatttt ctctccaatc agacctcaca cgaaaatcat ttctgtctcg attttagcat
     4201 gttttctttg ggaatgcttt aggttctgtt gcaaagtttt aaataaagaa taaagtccct
     4261 tacggtatct atgatttaag ct
//
LOCUS       DADLIO010000134         4156 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.142, whole genome shotgun sequence.
ACCESSION   DADLIO010000134 DADLIO010000000
VERSION     DADLIO010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4156
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.142"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            178..774
                     /locus_tag="JOX41_002787"
     CDS             178..774
                     /locus_tag="JOX41_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAY6450467.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
     gene            898..2697
                     /locus_tag="JOX41_002788"
     CDS             898..2697
                     /locus_tag="JOX41_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAY6450468.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(2975..3187)
                     /locus_tag="JOX41_002789"
     CDS             complement(2975..3187)
                     /locus_tag="JOX41_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450469.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            complement(4051..>4156)
                     /locus_tag="JOX41_002790"
     CDS             complement(4051..>4156)
                     /locus_tag="JOX41_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAY6450470.1"
                     /translation="ASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
BASE COUNT         1229 a          707 c          728 g         1492 t
ORIGIN      
        1 ttaaaaaaaa caagttatta aataagtctt tagttggatg tttttttgag atcaatcttt
       61 tatacttatg atgaacttac aaaattgttt gttttctgtc atatcaaaaa atggcgcagt
      121 tagttgcttt tctagtaaag tatagttaac aaagaacctc taaggagttg atgaataatg
      181 aatattgctg cctctcgaaa actgataaat ttcatatcca ttatcggatt aggcctatca
      241 atcgcgctga cgatttattt tattaattta ggtgttttca aagatttgaa tgcgttaaga
      301 ggattagtag gtgattccat cattttagga ccgattattt ttgtcttcat ccaaatcctg
      361 caagtagtta ttccaatcat tcctggaggg atcagtactg cagctggtgt cctgatattt
      421 ggcccttatg ctggatttat ctataactat attggaatct gcattggttc gattatcatt
      481 tttctgctag ggcgtcgtta tggaaagcca ttcatacttt ccatgattag cgataagaca
      541 tataacaaat atattggctg gctggataat caaaaccgtt ttgagaagct gtttgctcta
      601 gctatttttc ttccagttgc tcctgacgat gcgttatgtt tgatggctgg attgacaaac
      661 atgtcagtga aacgatatac actaatcatt ttgattgcta aaccactgtc gattttctta
      721 tatagtatgg ccttgattta tggaggtcaa tatctaagtg gtcttcttgg ataatattta
      781 ttttgtaaaa ttagtcattg attgacaatg ttaaatctgg gaaagggtct gcaaaacaca
      841 ctgcaccctt tcctttttca ttagatttgc gctacaatgt gaagagcagg tgataggatg
      901 aattatttga aacgtagctt aggtaatgct tgggactttt taaaaggaac acaagcttat
      961 ttccgtgatg tcttgctgat gcatggcttt attttattta tttgtttacc cttattgagc
     1021 agtacgaccc gttttatttt acaccgaggg gcaattgact atttgtctta tgacaatatt
     1081 ccttcaattt tttctcaaca tcctggggtt ctactctcgt taatcgtagt tttgatgacg
     1141 attttactgt tagtttattt cgaatttact tttcttttga tgagtgtttt ttttattaaa
     1201 aagaaagaac caatctcttt gaagcaactc ttacacttga cgatacttca gctgaagaaa
     1261 gtgagaccca ttactttttt gtttttcctt gcttattttt tattgattct accgatcagc
     1321 ggattaagtt ttaattctga tctactgtca aaaataaaaa tccccgcttt cattatggat
     1381 tttatttttg ctaatcgttg gatcatcgtc agttcctttt tactcgttta tattttcctt
     1441 ggctatattg ggattcgact gatttttgct ttaccggaaa tgattctacg agatcgtcct
     1501 tttcgagcag ccattcggga aagctggtca ttgaccaaat cgcgtctttt ggccatcacg
     1561 ggccaattta ttgtgattgg cggtacgatt ttactccttt cttctttagg atatatcgtt
     1621 gttattttgg cacaaagtat ggttgaacaa tttttcccag actatgcatt gatcagcgct
     1681 gtgtttgcta tgacgctttt acaagggatt ttattattca atatcgtgat gtctaccgta
     1741 gggatttttt atatcattgt tgatttcatg gatgacgaag gcttcttgcc tgagatccct
     1801 aagtggttta tcccacaagc ccccaacttg cgtttctctg cgctgaaaaa cactggtttg
     1861 actctttttg cagttttttt cggtattggc gtctgtcttt acaatatgga ttatctgact
     1921 tcagctgttc agacaaaacc agtgactgtc tctcacagag gtgtgagtac ccaaaatggg
     1981 gcgcaaaata ctttagaagc acttgaaaaa acaagcagag actatcatcc tgattatgta
     2041 gagatggatg ttcaggaaac aaaagatggt catttcgtag tgatgcatga tgcaaatctt
     2101 cgtcacttaa caggggtaaa tggaacacca caggatctta cattgaaaga attgacaaat
     2161 cttacagtta ctgaaaacgg agtgcaagcc cctgtttgtt cttttgattc ttatttggaa
     2221 aaagcacata agctaaacca aaaattactt attgagatca agacctctaa aaaagattcg
     2281 gatgaccttg tcgaacgatt tgtccataaa taccgcaaag ttatcttaga gaaccatcat
     2341 attttgcaaa gtttgacgta ccaaaccgtt tcagatttaa aagaagcaga accaaacttt
     2401 tatgtgggct acatcttacc tttcaatatt gttgggcccc ctgtgacgcc tgctgatttt
     2461 ctgacaatgg aatatagtac gatcaaccgt aacttcatta attctgccca ccaagacgga
     2521 aaagaagtat atgtatggac aatcaacgat tcagatgcta tgagtcgcat gatgttttat
     2581 ggtgtggatg gtatcataac cgatgagatg ggactactaa atgaaagtgt gaaacaaaca
     2641 gatgaagaaa tcacttattc agataaactg ctaaattttg ttttgggagt cggctaatca
     2701 aaaatcgtta atgaaaaaag tctttataca acaaaaaacg cataacctgc caccgcaggt
     2761 atatgcgttt tttgtttgac gctcataatg tgtgcttaac tttctcttga ttccttcatc
     2821 gcacgaacaa tagctaaaat agcaggaatt gcagagatca ctgcaagaat aattcccatt
     2881 ttccctgaac tttttctttt tggcatatct tctcgctccc ttctgtcttt atttatatta
     2941 taagggagtt cttgcgaatt ctcaaaaata ctgtttaaga aaccaattca gcaggtgcgc
     3001 taatatcaca gaattttacg agcatgcgat acttgctttc attgataagt tgatagtctc
     3061 gttggtcata actttcaaca tacacgacag ccgtgttgat atatgtacgt tcaatacagc
     3121 cgattagttc atgagatact ccgatcggtt tgcatatata agatcttcct acttctgctt
     3181 ttaccatttc attccctctt ttctttattt ttattttgtt ttttctttat tttataataa
     3241 caaattacct tgtatttgaa aacgttttta tccatttttt tattttttat tttgagtatc
     3301 tttctgcttt ttagataact attttttaac acgatcttag acgttgtgac aaaaacgttt
     3361 gtttatattc ctatgttgtt cgtgcgtttt tttctttata ttgctaagtt atttataaag
     3421 aggtgagcat atgatttata ttcaagcaat agtatttgta accttgatga ttgggctact
     3481 tatcggatta aaagaaaata gctaaaccat ttaagaaaaa ataaataagg aaaatgataa
     3541 atgcttttta attgcatcaa aaaacgtacg atgctaaact tggtataagt tcgaaagttt
     3601 aaaggaaact ttcaagaact aaattacatt acaaaggaga tgaattttat gacgtttaca
     3661 aaaacaaata tgcaataccg cgtagctttt gatacaactt ctaaccgttt tatggcgatt
     3721 gatgcacaaa acgaaaataa cgttgcgttt ggtattacaa tcgaacaagc agtccgagca
     3781 ttaaacgaat ctagataagg agtgaaccat tccaaatggc gactgatgag atctcggaaa
     3841 atcaataaaa gacgtttgta acggtaatcc gcgacaaacg tctttttgta ttcattacat
     3901 atatttggaa attgtctctc tttatctcta gacctaaaca aaaacacaag ttctaatatc
     3961 aaccatctcg ttttttatga caattttgtt agctgtttcg atgataatat tccgttatta
     4021 tctgtataat atttaatata atcttaattg tcaaattaag ttagacagat catcaatact
     4081 tacgtaactc aaaaatactt ccaaaggtgt tcgataatcc agtgattttc taggaatatt
     4141 atttcgttta gatgcg
//
LOCUS       DADLIO010000135         3925 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.143, whole genome shotgun sequence.
ACCESSION   DADLIO010000135 DADLIO010000000
VERSION     DADLIO010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3925
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.143"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(573..1130)
                     /locus_tag="JOX41_002791"
     CDS             complement(573..1130)
                     /locus_tag="JOX41_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450471.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(1309..1920)
                     /locus_tag="JOX41_002792"
     CDS             complement(1309..1920)
                     /locus_tag="JOX41_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450472.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSAQYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            complement(2033..2290)
                     /locus_tag="JOX41_002793"
     CDS             complement(2033..2290)
                     /locus_tag="JOX41_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450473.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            complement(2887..3165)
                     /locus_tag="JOX41_002794"
     CDS             complement(2887..3165)
                     /locus_tag="JOX41_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450474.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            complement(3199..3450)
                     /locus_tag="JOX41_002795"
     CDS             complement(3199..3450)
                     /locus_tag="JOX41_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450475.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
BASE COUNT         1195 a          799 c          520 g         1411 t
ORIGIN      
        1 ttattccgaa taaatggtgt ccaaaagctt gcatctgcca gattatctca tttcttatga
       61 caagctaagc aaattatctc caccaaataa tttattcata tttttgactt gcgcatacta
      121 actaattctt aaattttcat acaaaatttc tcaatttccc ttaacgagta atatttatgt
      181 acggtgattc tcactagtat cccaatcact ttttaagtta tcccgatttc aattctactt
      241 caaaaatagt tgcttttatg tatgctgtta gttgattaga tggtcatttg ttgagctagg
      301 tcgtttattt taaacaagtt gtttctttag cttataccta tctcgtctac caaacgcaag
      361 atggcaaaca caaatgcata cgcatctgta tttgccactt tgattcgtat aaagctaaca
      421 actattaact cctctcagct aatagttgct ctctttttta ttcagattca tttttgctga
      481 tcacagccta gtatttcaat ggttttgaac actaaaccaa attgttccat tacaacattc
      541 actggctgat gaaatggatt agtagatttc gattattcaa agcgattttc tattggtgga
      601 tcgtgttccc aactaataag acggattcca aacctatcgt acagatcttc taaaccactt
      661 ataaattttg cacctatttc aggtgtttta ttgcgtggat attctattgt tacgccatta
      721 aatggatacc aattaggatt aggctctctt tttttctgta catctcccat agaatagtta
      781 gcactttctg ggacataata tattcttcga ccatcctcta attcatctaa taagatattt
      841 cgtgatcgtc tatcacttgc taaatgtaga cgccacgtgc gataccatgc catgctacct
      901 gcatctgcag aaaatccatc aaataatgca acaattgtat cttctatcac aatcctttcc
      961 ccatctactt catattctaa tctaaaatca aactcccctc gggtaatttc tggtcttggt
     1021 ggcttaggac ccaatattat tctacttaaa accgcattcg ttcccagatg aaacacagct
     1081 ataacaacaa taatgattaa tattttgttt ctatttgata aatttctcat tattcgcaca
     1141 tcacctctac attctcacat attagttcgt aatactcctt taatatcaaa atatctactg
     1201 gtcgtaataa tattcgctat gaattcctac tactcgtata agaaaggcca aatcatcagc
     1261 ttttacttgc tgatgatttg gcttgtttct atttatcgta attgttttct aatcaccaaa
     1321 attgttaaca atcggttcag atatttccca gttgattaag gtaattccgt attgtgtcaa
     1381 aacttcttgc gcttctccga aattaagtac agttcttatg tatccacttt ctcctaatat
     1441 aaagtctacc tctcttttaa aaccttcctc gagatttcta agggctatat gtggttttaa
     1501 tgacattgat tgtacatttt cccccatata atattgcgca cttcctcgac taaaatagat
     1561 tcctagatcg tccccaaaag gtagatcttc tctaccacta gctaatctac ttctccatct
     1621 tcgttctctt ttcatagaac ctgcgctgaa ctcacacccg ttaaactcag ctatgacagt
     1681 atcttcaatt atgttaatct gtccatctag ttcgtattca atcctaaatg gaaattctcc
     1741 ataggtgatt tccggttcgg gtattttagg tgagattaat gcaaagaaag gaaatattaa
     1801 gcttggcaac atcaaaaaaa ctcctcctat gatcacaatt cccgatgtaa tccaaaatat
     1861 aatttgtaca attctcattg atccattgta ttccatttta ttccccctat tactattcat
     1921 atccgcctat ctatatcgat cttccaatgc agagataatt gcttccatac cttgattttt
     1981 tactgagtta cctatgcgag atatcattct ccactaaggt gcatcatatt gtctatctaa
     2041 catgattaat tctccaatag gtgtatactc ctccaaaaac aacatttaat gcatctccct
     2101 cgacaacata agctaccatg tttgctgtat atgtgtttga gtctaattca taagcagata
     2161 aatttactgt cgctggatta aatataatcg cattcgtatt tatagctact gaatttgctg
     2221 cttcagcacc accttttgaa tgtccgatca ttgtgatttc aatagtagga tttacgtgga
     2281 cagccctcac cgtttaccct gaccattata gaaatcgctt acttttttga actacgcaac
     2341 aaaggataca atgctcctaa cttcactgtc tccatttttg tccactaagg aatataaaaa
     2401 ataggcatta attcatttaa ttcggtcaca acacgttacc ttttaaatca ttatactgta
     2461 tctcatacat tattatcaat aaactattat aaaaatgcaa aaaatgcttt atcaatctat
     2521 tttgtaattg gtcataatat cattgaaatc ataccctgta tcgatttttc ctatgaatct
     2581 cgtctatttg tgattgacga aaaagaggca agacagacac tggaatggta attttaccca
     2641 ctattttgct ccaactattt gtaatcgtac ccacttttga aataccgaga tgatcatttt
     2701 aattgatatg ctgattccca agcaaaaccc caagaaatta aatgctctat cgcatctagc
     2761 ttcttgggtt ttgcttatat aaattccaac atttaaattt tttatgctgt tcggtctcag
     2821 aaatgccgtt tttgcttata tcacaatatc aagatgtcaa attattcgtg ttgccgatga
     2881 ctttgattaa tttttttcaa attgtttatt aagactaatg ctgtcttttt gcagatacca
     2941 atgttcgaac tttttaacat tatcatatga tcctgcaagt tttaacttct taccattaga
     3001 tgttatcaaa gttataatta accttgcctt tttcccatta ggatctttta ttttatgaat
     3061 tttctgcagg taatctctcc taatggcagc tatttttacc tcatcagtgc tgataaacca
     3121 ttgatcatcc acatacatac tgcctgttat gttgtgtttt tccatttctt ccgagaacga
     3181 aaagtttaag gctcgttctt acttccaaag ttgaatgagt ccatggattg gacttagtgt
     3241 gagaattgag aacaacaata agaatccata tcctcccgca aacatcccta aggctatact
     3301 gtctctccat ccataagtag gattagaaga gaaaagagtc accgtttgta ataatatgaa
     3361 aaggaataat ccagcacaaa caccaaagat aacaactcca aacattgaat ttttatacaa
     3421 tgaccattta tttataggct tttctttcat tttacttccc cctactgttc tgttcacacg
     3481 gaatgaattc aaagttcata agccctcctc tttgaacata tgaatacgac ttgctaacta
     3541 tactttaaaa aagcttgttt taagcggtta taggcgagtt gtaatctcta ttcatctcat
     3601 tagcaaataa cttgccgaaa agtctactga aattaaagca gatagtggaa gaattattta
     3661 gccaggatag acactatttg tgaaacacat gtctttactt ttgaaattct atgatgaaaa
     3721 gccttggaat acagtagctc ttaattggta atactttttc cattataaat aacctctttt
     3781 cattttatat ttatcccctc taaaaataat atctaatcta atattttaaa cttatatttc
     3841 cctcgctgtg ctaatagagc attactaaat aaatagaaac tagaaaaaag cattacgcct
     3901 gccagaataa accaattatt tgtat
//
LOCUS       DADLIO010000136         3863 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.144, whole genome shotgun sequence.
ACCESSION   DADLIO010000136 DADLIO010000000
VERSION     DADLIO010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3863
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.144"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(245..466)
                     /locus_tag="JOX41_002796"
     CDS             complement(245..466)
                     /locus_tag="JOX41_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450476.1"
                     /translation="MEEEKIFEKRWELASVEQRARYHNLMSSYRNIDWTYKEKKYLLW
                     LCQLDVNTFETFEVILDKIKNSNEKRADL"
     gene            complement(564..809)
                     /locus_tag="JOX41_002797"
     CDS             complement(564..809)
                     /locus_tag="JOX41_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450477.1"
                     /translation="MDFPEVVKEVQEIGATISDSRSSPMNYQDAHGIKIIDQERNVRK
                     YTTINECVINENLCRAPITKHIKNRSKAKDGRTFTTF"
     gene            1049..1663
                     /locus_tag="JOX41_002798"
                     /pseudo
     CDS             1049..1663
                     /locus_tag="JOX41_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337511.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(2033..3034)
                     /locus_tag="JOX41_002799"
     CDS             complement(2033..3034)
                     /locus_tag="JOX41_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HAY6450478.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYINNSSGQSVINKQIVENSDILLAIFGHKLGSPVDNYRSGTIAEIDY
                     FYKNSKGEVGVFFLDEPVPQVLAEEYIEVKKYRDSLEDKGFYGTYSKDNIRRFLTKKV
                     NYLIEKAQNNLESKRFDLDSISYKTPSVINKKVTGTDKDFDDNLDIFDPIEFDNDERL
                     LLIYAFMDENSIFSTDNSTYRKVVQWESDNNLRSYLSDRVFDVLEKLSKSGILKEEYD
                     SSFDEYPSRYILISEDYKKFKRYFLKNEKKISVIMEKYKAPIQADPFSNLDESDLPF"
     gene            complement(3193..3459)
                     /locus_tag="JOX41_002800"
     CDS             complement(3193..3459)
                     /locus_tag="JOX41_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAY6450479.1"
                     /translation="MMIKKLIEEKQKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            complement(3449..3805)
                     /locus_tag="JOX41_002801"
     CDS             complement(3449..3805)
                     /locus_tag="JOX41_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAY6450480.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVVNGRYVITHGFTKKTEKTPISE
                     LKHAKELREEWFTNDD"
BASE COUNT         1222 a          698 c          512 g         1431 t
ORIGIN      
        1 ttactatata cttcttccca gaacttgtcc gtctccttca aattatctct acctctcgag
       61 ttcattgggt ggtttgccca tttattaaac atggaatcac ctttctcata ctcatatatt
      121 tatgtcctat ttcaattata tttatatatg cttaaataaa tttgtatcct gaaatttatt
      181 gtaatatgaa gctgtatttt acatatagta accaaagagt taataaaata aaaagagcga
      241 accattatag atcagctctt ttttcattgc tgtttttaat cttatctaga atcacttcaa
      301 atgtttcaaa ggtatttaca tctaactgac ataaccaaag caagtacttc ttttctttgt
      361 aagtccaatc aatattacgg taagaggaca ttagattatg gtaccttgct ctttgttcaa
      421 ctgaagccaa ttcccagcgt ttttcaaata ttttttcttc ttccattatt gatccctcgc
      481 aagacgctac ctcaaactta aataatgggc agcgaaagtc taattcctta gatctaagta
      541 tagcaaacaa atatgaaaaa aacttagaag gtagtaaaag ttcttccgtc ttttgctttg
      601 cttctattct taatgtgttt cgttatcggt gccctacaaa gattttcatt aattacacac
      661 tcatttattg ttgtgtattt tctgacattt ctctcttgat caattatttt aattccatgg
      721 gcatcctgat agttcatagg agaggagcgg ctatcagaaa tagttgcacc tatctcttga
      781 acttctttta caacttctgg aaaatccatc catcctgctt cagctgtcaa aagtaataat
      841 ctataatatt tatctttcct tttcaatcta agaaatcgtc accccattct ttttcttcta
      901 ttataaacta tttaactttt agaattcaaa aaccgtttgt ctatttagag tttaccctaa
      961 atagacaaaa atataacatt gaaaaattta gagttctaac gtatgattag ggtgtattat
     1021 aaacgttata gaaaagtagg gaataaattt gaaaattgct tatattagag tttcatccat
     1081 cgatcaaaat gaacaacgtc aaattgaaga aatgaaaaag tttggcgctg aaaaaatttt
     1141 tatcgaaaaa caatctggag cgacgattag tcatcggccg attttccagg aagctttaga
     1201 ttttgtcaga gagcaagata tttttattgt agaagccatt gatcgacttg gacgcaatta
     1261 tgacgagatt atcgattcag tgaattatct aaagaagaag aatgtgcgac ttattatcac
     1321 cagtttaccg atcatggctg aagcaattgg aaatcctctc ctagataaat tcatcaaaga
     1381 cttaatcatt taaatctcag ccatgattgc tgaacaagaa cgtactgaat cgaaacgacg
     1441 ccaggcacaa ggaattaaaa tcgctaaagc aaacggcgtc tataaaggtc gtcctaagtt
     1501 atacagtgca gacaccaaag atcctcaacg tcgccttgtc tataggagta tcgttcagga
     1561 tcttgagaat ggggttgcta tctcaaagat tgcaacagac tacaatgtga ctaggcaaac
     1621 aatttaccga ataaaaaaag aaatcgacca actaattgta tgatttcttt tttgaatcac
     1681 gtaattatta attagctttg tcatcaatac agacaatcat tttagattca tctagctaag
     1741 ttgattacat ttatgttaaa aagaatttag ttaacataaa tataattgat gcataaatcg
     1801 tccttattta aaggcattta acattgacaa cttagtataa tgtatcttat gtaaactaat
     1861 aagatttgaa ttttatttta tacacactcg ataatagatc aattttatgg tcccccgcat
     1921 ttacgattgc acaagagaaa cataaagtcg acctattagc atttcttttc aattcaaaca
     1981 ttaaaaaagt ttatacctct gctactaaaa aatgaaatta tctatttaaa atttaaaacg
     2041 gtaaatctga ttcatccaaa ttggaaaatg gatcagcctg tattggagct ttgtatttct
     2101 ccataataac agatatcttt ttttcatttt ttaaaaaata ccttttaaat ttcttatagt
     2161 cctctgaaat caaaatatag cgtgatggat actcatcaaa agaagaatcg tattcttcct
     2221 ttaaaattcc cgatttactt aatttttcta gtacatcaaa tactctatca ctcaagtaac
     2281 tccttaaatt gttatcactt tcccattgaa ctacttttct ataagttgaa ttatcagttg
     2341 aaaagataga attttcatcc ataaacgcat atattagcag caatctttca tcattgtcaa
     2401 attctattgg atcaaaaata tctaagttgt catcaaaatc tttatcagtt ccggtaactt
     2461 ttttgttaat tactgaaggt gtcttgtaag aaatagaatc taaatcaaag cgttttgatt
     2521 ctaaattatt ttgtgctttc tcaattaaat aattcacttt ttttgtgaga aaccttctga
     2581 tattgtcttt gctatatgtt ccataaaaac ccttatcttc taaagagtcc ctgtacttct
     2641 taacttctat atactcttca gccaaaactt gtggaactgg ttcatctaag aaaaaaaccc
     2701 ctacctcgcc tttgctattt ttataaaagt aatcaatttc tgctatagtt cccgatctat
     2761 aattatcaac tggagaaccc aacttatggc caaaaatcgc taataatata tcactatttt
     2821 ctacaatttg tttattaata acactttgcc cagagctatt atttatataa gtaggaatcg
     2881 cattcgtttc ccatcgaatt ggcatcaaaa ttacttttgt attatctgta ttttctatat
     2941 tccatctata tatggtttct tctacttcat tcctctttgc tgctatatca cctggtgatg
     3001 ctataaatac ttttattaga tttatggttt tcatttattg tacctttctc tttatgtctc
     3061 tttaaagtaa tttttgtata aaatttattg acttttacac tataggacaa cttttatcta
     3121 tttagtacaa aaaggcccac taaactaatt gattagttag gagcctatta caggtatatt
     3181 ttcaactcgc ttttaagcaa attctactac cagctttttg cctaatgccc tagcgatatc
     3241 atcaagttta tcgaaagata cgttatcccc tctctcaatt cgagcaatag tagattgagt
     3301 tgtatgtgct ttttgtgcaa gctccgcttg agttaggcct gcttcctccc gtgcatgata
     3361 aagagcaacc gcagtttcga gttttcttcc ttcacggtca tatgcttctg caaaatcttt
     3421 gtctttttgc ttttcttcaa tcaatttttt aatcatcatt tgtgaaccac tcctctctaa
     3481 gttcttttgc atgtttaagt tcacttattg gtgttttctc cgttttttta gtaaatccat
     3541 gggtaatgac ataccttcca ttgaccacat ggaaatagat agctctttgg atgtttgatc
     3601 ctaccttact tcttaattcg tacaaattag tgtctaattt tttcacccat ttcaaccgtt
     3661 gagctactag catcccattc ttttctgttt cttctattgt acgtaaaagc ttcgcactat
     3721 ctttttttgg taatgtttcc aaccattcta aaaattcatc atgaccatta ggtcttttaa
     3781 atgtttcaaa agatattttt tccataccca attatatcat atattgattt tatattatag
     3841 tatataacat aaaaattcga att
//
LOCUS       DADLIO010000137         3780 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.145, whole genome shotgun sequence.
ACCESSION   DADLIO010000137 DADLIO010000000
VERSION     DADLIO010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3780)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3780)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3780
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.145"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(<1..2232)
                     /locus_tag="JOX41_002802"
     CDS             complement(<1..2232)
                     /locus_tag="JOX41_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450481.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTG"
     gene            complement(2904..3172)
                     /locus_tag="JOX41_002803"
                     /pseudo
     CDS             complement(2904..3172)
                     /locus_tag="JOX41_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
BASE COUNT         1101 a          806 c          580 g         1293 t
ORIGIN      
        1 accggtttgt agcgtttctc cttctcggtt ctgtaactca aaaacagctc cttgaaggac
       61 ttcaccactg ccttcagcat gtttaattag ttcaacacca cccgtatcaa ggatgttttc
      121 aatggttaac gtcacttctt ctatggagta ttcatttata aaaacatcat gtaccgtcgc
      181 atctaaaaga tacccttccg gtgcttctgt ttctcggact tgatagctac ctacaggaag
      241 cggttcactt aaaaattctc cgttttctgc cgttatacct tcttgtatca cttgtgaatc
      301 gcttgataaa atttcaaatt ttgctcctgc cagcctttgg ccattctcat cagttttaat
      361 tactttaata cgcccatcga ttttccttgt tcttacagta ctcgtattca atcgattgtc
      421 actattcaca agcgttgcaa agtttaaaat ttgatcgccg accgcatacg cctctacatt
      481 gaccttaaaa gagagggtaa aacttgtcgg accaccaatc gtattattcg cactgaaacg
      541 aactattcca ttattgactt cggcatcaat gaaagaggga atatctgata gaaatgacac
      601 aaattccatg ccttcttcca aaacatcttc aataacaagc gtatttcttg ttccagaaaa
      661 catcgagaca tgcagagtat acgttagttc attttcattg agattgataa catttttgtc
      721 cacacttttt cttaaagaga ttgccggaag attactttca gggattctca agcggtagtc
      781 tcggctcatt acctgattat tgtaggtcat actcgctcga ttccgagaaa acccatcctc
      841 ttgtcttcct tcattgaaca agtcgacatc ggtcacttca agagcatatt caataaaata
      901 cgattgaccc tctgctagat taccaaagtc cacaacaagt gtattcgttt ccttattaaa
      961 agatactttg tccacaaatt cctcggaaac ataatgagtt ctaacgtttg cttcacctgg
     1021 attcgttact tctgcgatcc gaaccccacc tgaaataggt tctctatttc cagtggaact
     1081 ccatgtagtc ggattcggtg ccaaagttgt tccttgcggt agtacatcgg taaccactac
     1141 accgtctttt cgtgatcctt cataatttac ctgcaaaata aatttattac tgttggtcac
     1201 gtcttgcccg tcaatcagca gattcccaag atttccttgg ctgtcgattt ctctagagcc
     1261 atagtataat ttcgaaaaaa tgggtcttga tgaaggaata ggcgtaattg aaaattccgt
     1321 gtttgctgct cgctcagcat aagtaagact cacttgaaag tcattatttg gctcagtacc
     1381 gcctgattga aagaaagcaa cttcaaacgt gatactgaat gtatacgact gagcggcttc
     1441 atttaatcct tcataatcaa aggtaaatgg aaaaacaacg tctgtgcctt cttggtaaaa
     1501 tgccagtggc tttaaaggtg aatcatcagc gacctccact ctaatgaact caattaagcc
     1561 aatcgatgct ctaggaactc gtacgaccat ctccccatat tcttcaagaa tatcgccagc
     1621 gcctccttga atgtatccct ttaacgtttg tgtatgcctg ctcggcaaag tggggcgctc
     1681 agcagagatg ccgatgtcat aattcaagag ctcctcttgt ctttcaatct gagattcctg
     1741 cgttatagat ggctcagatg atctggcttc attaaaagat tcacttaagc tttcttctgg
     1801 tatattaaaa gattcacttg tgctttcttc tggtacatta aaagactcac ttgtgctttc
     1861 ttctggtaca ctgatttcta ttgagaccgt atttgattga atatcaccgc ttcttgcggt
     1921 caattcgtat ttacctgaat gctgggaaga ataagtaatc agacgttcgt aatcattgag
     1981 ttgcttcact tccccttcaa tcaaatcctc actcttatca atgaccaatg catttagcag
     2041 gtctggtgtt cctctgactc gcaactggaa ctgctcaccc aaagcagcct cctcttgatc
     2101 aacttcgatc gtcagcgaac gctctggctg ttctgctaaa gactcagcta gaaccgttat
     2161 gttcccaaat tgattgatca caataagcat aactagaaac atacttaaca gtttatgaaa
     2221 tttgttcctc actattactc ccccttataa ttttgactaa acaacaaggt acccgataat
     2281 tttctaaaaa gattccccaa ctcaaaatgg ctgcgttacc tccctcgtat tttcggttca
     2341 actcaagcgt tgcaatgtaa gctgtaaaca aagctaatga ttgccgattg tcttctgttg
     2401 attgattcga tagctttgta tgacttttag ttgtccgtgt ggcttaacca taattatgat
     2461 ttcacgattc ctcctgccag tgccttgcac aagctggagc gtaaccctaa tagttatttt
     2521 gttaatgtac ttatatactt ttatactttt ccattagaaa caatcactaa atcgttgata
     2581 ccaaggtcag actctagaat ttcatcagtg agtccctgta ttggttaacc ttcatcaatc
     2641 ccaaaaaaat atatcaatgc ttagcatcaa aatgaatata tagtttagaa tacttgggat
     2701 tcatcgataa ctgatcgctt atttggccat attatttggc acttggttca actaaacgca
     2761 tttaggatgt tccttcattc tcgtcatgga tgttctcaaa ccgtcattac taataaactg
     2821 tccaccgaat cgatggttca tttcttgcat tttccacgtc caattactct ttttgctctt
     2881 tatttgggcg tagtttcact ttcttaactt gtatcgtctt ccatcaactc cttaatcatc
     2941 ttcttagctt tattggctcg gtttccttgt aaaaggtatc tacaaatagt gacaatctgt
     3001 attaaatctt catcattttc tgtaatgtca ataatttcta tattctgtac catatattgc
     3061 aaagggtttc actaagttca taaccgaagc gaattaaaca acttttgtat agaataacta
     3121 ccttttctat ttttccattg gtaattctat ctattaattg gtttaatcct tttgttgtag
     3181 ttgattccac taccaagatg attctctcga attttaaagc ttgaagatgt attgctattt
     3241 ttgctaactg gcgtatttgc aactattttt cccttctatt cttccttcat tgattcccct
     3301 ctaaaattac tatccataaa aaattgcata aatgacaata gtatttatat tagtcatact
     3361 gctttttaac acagcaaatt ccagaaaaac attcgttaca tatttgtgaa tttttccaaa
     3421 aaataacatt tttataaaac gacgaaaaat aaatcactac cagtcaactt ctataatatt
     3481 accaaataac aaactaacta tccatcaata acgtgtttta ttttttaaaa tttctataaa
     3541 aaaacaatca ttcttaaaaa gaatatataa aaataacaat aacctttgtg atttttcttg
     3601 tttgaagaat gttagaagaa aaatctctaa atacttataa ttattttata agcaaaaaaa
     3661 tgctatcggt agtatcaccg atagctgagg aaagtcacag tagggactat ttgattaaaa
     3721 aatatgttta ttcaatccat ctatttattt ttgccttatt aacatattgt aataatgtaa
//
LOCUS       DADLIO010000138         3604 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.147, whole genome shotgun sequence.
ACCESSION   DADLIO010000138 DADLIO010000000
VERSION     DADLIO010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3604
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.147"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            <1..188
                     /locus_tag="JOX41_002804"
     CDS             <1..188
                     /locus_tag="JOX41_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAY6450482.1"
                     /translation="VEDASLSGENERINELIEFIRKNKFRTLEYDDKLVRKIIQSVTV
                     YEGHFVIAFKSGIEMEI"
     gene            331..555
                     /locus_tag="JOX41_002805"
     CDS             331..555
                     /locus_tag="JOX41_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAY6450483.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGEEIKISNE"
     gene            570..1439
                     /locus_tag="JOX41_002806"
     CDS             570..1439
                     /locus_tag="JOX41_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HAY6450484.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDKNRNNLVVPPGAWGDWINGGGWLFINGYHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGVEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            1420..2154
                     /locus_tag="JOX41_002807"
     CDS             1420..2154
                     /locus_tag="JOX41_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008766909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAY6450485.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            2187..3095
                     /locus_tag="JOX41_002808"
     CDS             2187..3095
                     /locus_tag="JOX41_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HAY6450486.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            3092..3572
                     /locus_tag="JOX41_002809"
                     /pseudo
     CDS             3092..3572
                     /locus_tag="JOX41_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
BASE COUNT         1252 a          521 c          789 g         1042 t
ORIGIN      
        1 tagtagaaga tgcctccctc agtggcgaga acgagcgaat caatgagctg attgaattta
       61 tccgcaagaa caaattccgc accttagaat atgatgataa gcttgtaagg aagataatcc
      121 agagcgttac agtctatgaa ggccacttcg tcatagcctt caaatctggc atcgaaatgg
      181 aaatatgaaa accagaagta aatagcccat gactctacag tagagttgtg ggttttcttt
      241 tgcttgctga ttataataat attttaataa ctattgtgtt tatcaaccaa atggtttata
      301 atattcttag cgtaaacttg gaggtgctgt atgactacgg cagaaatgat taaagaactg
      361 tgtgagcaaa tgaatataag tgtttccgaa cttgctagac gtattggcca gactccacag
      421 aatttcaata aaaaattaca acgagaaaca gtaaccttgg atgagttgaa ggccattgct
      481 gatgtgctag gtgtcaagtt tgtgcaggca tttattttac cagatggaga agaaataaaa
      541 atatctaacg aataaaggag gatgtttata tggtaggtaa tgttattcaa atagtaacag
      601 agaaattatc atctttgcct tttatagaag gcatcgtatt agggggctca cgtgcaagag
      661 gcacccatac agaaaattct gatatagata tcggaatcta ttacaattca gactcatttg
      721 acctgacagc gattaatcaa attgctacag aattggatga taaaaataga aacaaccttg
      781 ttgtgcctcc cggagcgtgg ggtgattgga ttaatggcgg cggatggtta tttataaatg
      841 ggtatcatgt tgacttgatt ttacgtgata taaaacgggt agaacaaata atcaaagata
      901 cggagcaagg aattgttact gccaattatc agaccgggca tccccatggt tatataagtg
      961 caatgtatcg tggagaatta gcgattagta aaatactata tgctaagaac gaaagcttat
     1021 gcgaattaaa aaagcaggca gaaatttacc ctactgctct aaagaaaagc ttgatgaact
     1081 tttttatatt tgaagctgaa ttctctttaa tgtttgtaaa agcaaatgcg ggggtagagg
     1141 ataaatatta tattgcaggc catgtttttc gtattatttc atgcttaaat caagtactat
     1201 ttgcatgtaa taatgcttat tgcattaacg aaaagaaagc tataaaactg cttgaaactt
     1261 ttgaatataa acctgaaaaa tatgccgaaa gagttaatca tatttttgaa gtactcggtc
     1321 tttctctttt tgaatgctac gatatgaccg agaaacttta taaagaagtg aatgaaattg
     1381 tatcggagat aaataacttt ttaaacgagg agagttcaga tgaaagaaaa caaatatgat
     1441 gataatatat tttttcaaaa atacagtcaa atgagtcgct cgcagaaagg actggctggt
     1501 gcgggagaat gggagacttt gaaaaagatg ctacctgatt ttaagggtaa gcgtgtgctt
     1561 gatttaggat gcggctatgg atggcactgt atatatgcga tggaaaacgg tgcttcctct
     1621 gtagtaggtg ttgatatttc tcataaaatg ctcgaagtag caaaaggaaa aacccatttt
     1681 ccacagattg aatatgaatg ctgtgccata gaagatgtgg atttcccaga ggagagcttt
     1741 gatgtaatac taagttcgct tgcgtttcat tatgtagcag actatgagaa tttaataaaa
     1801 aagatatata ggatgctgaa ggctggtggc aatttagttt ttacagttga acatcctgtt
     1861 tttactgctc atggaacaca agactggtat tataacgaaa aaggagaaat actgcatttc
     1921 ccggtggaca attattatta tgagggcaaa cggacagcta tgtttttgga agaaaaggtt
     1981 acaaaatatc atagaacact gaccacatat ctaaatacac tgctttcaaa tagttttata
     2041 ataaatcaga ttgtggagcc acagccgcca gagaacatga tggatattcc ggggatggcg
     2101 gatgaaatgc gacgcccaat gatgctgatt gtatcggcaa aaaagaagat gtaataatat
     2161 agaaaaaata aacgaggagt atgtaaatga gatcagaaaa agaaatgatg gatttagtac
     2221 tttctttagc agaacaggat gaacgtattc gaattgtgac ccttgagggg tcacgcgcaa
     2281 atattaatat acctaaagat gaatttcagg attatgatat tacatatttt gtaagtgata
     2341 tagaaccgtt tatatctaat gatgactggc ttaatcaatt tgggaatata ataatgatgc
     2401 aaaagccgga ggatatggaa ttattcccac ctgaagaaaa gggattttcc tatcttatgc
     2461 tatttgatga ttacaataaa attgatctta ccttattgcc cttggaagag ttagataatt
     2521 acctaaaggg cgataaatta ataaaggttc taattgataa agattgtaga attaaaaggg
     2581 acatagttcc gactgatata gattatcatg taagaaagcc aagcgcaagg gagtatgatg
     2641 attgctgcaa tgaattttgg aatgtaacac cttatgttat taaaggattg tgccgtaagg
     2701 aaattttatt tgctattgat cattttaatc agattgttcg ccatgagctg ctgagaatga
     2761 tatcatggaa ggtcggcatc gaaacaggct ttaaattaag tgtaggcaag aactataagt
     2821 ttattgaaag gtatatatcc gaggatttgt gggagaaact tttgtccacc taccggatgg
     2881 attcctatga aaacatatgg gaagcattat ttctatgcca tcaattgttc agggcggtat
     2941 ccggtgaggt ggcggaaagg cttcattatg cctatccgga gtatgatagg aatataacaa
     3001 aatataccag ggacatgtat aaaaaataca ctggtaaaac cggctgcctg gatagcacat
     3061 atgccgctga tatagaagag aggcgggaac agtgattaca gaaatgaaag cagggcacct
     3121 gaaagatatc gataaaccca gcgaaccatt tgaggtgata ggtaagatta taccgaggta
     3181 tgaaaacgag aattggacct ttacagaatt actctatgaa gcgccatatt taaaaagcta
     3241 ccaagacgaa gaggatgaag aggatgagga ggcagattgc cttgaatata ttgacaatac
     3301 tgataagata atatatcttt tatatagaag atatcgccgt atgtaaggat ttcagggggc
     3361 aaggcatagg cagcgcgctt atcaatatat ctatagaatg ggcaaagcat aaaaacttgc
     3421 atggactaat gcttgaaacc caggacaata accttatagc ttgtaaattc tatcataatt
     3481 gtggtttcaa aatcggctcc gtcgatacta tgttatacgc caactttgaa aacaactttg
     3541 aaaaagctgt tttctggtat ttaaggtttt agaatgcaag gaacagtgaa ttggagttcg
     3601 tctt
//
LOCUS       DADLIO010000139         3540 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.148, whole genome shotgun sequence.
ACCESSION   DADLIO010000139 DADLIO010000000
VERSION     DADLIO010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3540
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.148"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(266..970)
                     /locus_tag="JOX41_002810"
     CDS             complement(266..970)
                     /locus_tag="JOX41_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450487.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(1157..1402)
                     /locus_tag="JOX41_002811"
     CDS             complement(1157..1402)
                     /locus_tag="JOX41_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450488.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(1419..2270)
                     /locus_tag="JOX41_002812"
     CDS             complement(1419..2270)
                     /locus_tag="JOX41_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAY6450489.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            2436..3440
                     /locus_tag="JOX41_002813"
     CDS             2436..3440
                     /locus_tag="JOX41_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HAY6450490.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
BASE COUNT         1098 a          603 c          687 g         1152 t
ORIGIN      
        1 ttttttctct atcagaaaat atgtttatta ttagaatttt ttatagttaa ggttaggcat
       61 cttaagaaat caggcaactc caagatatct tcaggtagaa gagaagtcgc ctaacattgt
      121 aggatcatag gtgatttgtt ggacaggtca agctgatatt tgagcctgat gttagaagga
      181 atttcttttt acttgctgta gaaattatta tatgactaaa aaggctggga ttttaaatcc
      241 cagcctttta tgacaaatag aatttttatc gatcagtaat cgctgtcgct gcaaattgtt
      301 cgatcaaagg aatcaaagtc aatttgactt tgtatttccg ttcgagtgct ttttcgataa
      361 cgaactcatt ttcagtagtc atagaaatag ttgctaattt acgaggttca tcagcatttt
      421 tttcattaat aactacttca tgttcatttt gttctgtgta aaatttagga tactcagcaa
      481 cggcttttga aaaatcagca aaacttaaag cggcattcgt atcagttgag cgtgtatttt
      541 cagttgtgtc cgcttttggt ttttccgttt tttcttctgg cacactgact gtttcttctg
      601 taactggtgt cgcaacagct tgcgcagttg gttcatcgtt tttcaatcgt tgatcattcc
      661 agtaagacac gatttcaata agaagattgt cacggaatcg ttcgaaaatc ccgttttctc
      721 ctgaacgaat tctctttaat acagtattga agttgtcatc gattggcacg ttgatccgtg
      781 tatcttcatt tgttttccca gctaatccga tcgttaagat ttgacggttt ttgggatcaa
      841 gcatgacttg taacggcaaa ccataacgtc gcaagctctc ttcttctaga gaacggaata
      901 attgtcctct tacaccatcc aatgaaggac ggaattgatt taataatttt tgtttctgtt
      961 ttttcttcat atgttctctc cttcgctcat accctttcga ttataagaaa aaaacagcca
     1021 aatgaaaagg agtaatgcaa aaaaacttgc gtatacgcaa attacaacag aaaaatttgc
     1081 gtattttccc gttttttgaa agaaaaataa aaaatggaac ggattatgta tatatacata
     1141 atccgttcca ttctttctat tttttcggta tcaaggcaaa aacaggtagt tcaggtgaat
     1201 aaatgacttc atgttcgtgc cagggtttga ccattagcga atgatcgaac cgttttttca
     1261 gttcttcgat gatttgatca tgtgtccagt ttcttgcagg aaaatgttgg attttctctg
     1321 catcgatcaa aaagacaaaa tcggaatgaa aagtctgggt aacttcttcc gagagagaat
     1381 tcaagcgttc gattggatcc ataaaatcac ctttcgactt aaaattgggt agtatctggg
     1441 tcttttgctt tgccgactac accatctaac tgatcgattt gtttcatttc ttcttctgtt
     1501 aattcaaaat caaataattc agtattttct ttgattctgc ttggtgtcac tgacttagga
     1561 agaggaagga attcgtgttg cagcgaccaa cgcaaagcaa cttgtgcaat cgtcttgtca
     1621 tgtgcttcag cgatttgttt catttcaggc acatcgaaga ttttaccagt gcctaatgga
     1681 ctatatgctt cgaggatcat atcatgtttt tttgcatact caactacagt tgtctgtaat
     1741 tcgcctggtg caaggaaaac ttgattgacc atcggcataa tttttgctgt ttttgctagt
     1801 gtatctagat ggtggggtaa gaaattgctc acaccgattg ctttgatttt acctgcttca
     1861 tacagttctt caaatgctcg ccatgtatct gcatttgctt gttcccaatt atcacgaaaa
     1921 gcaacagggt ttggccagtg gatcaaaaac agatctaaat aatctgtttg gagcttcttc
     1981 aatgattctt caaaagaaga catcacaagt tcatagctgt ggtttgcatt ccataatttt
     2041 gttgtcaaga atatctcttc tctaggaatt ccactttcct taatcgcttg gccgacgctt
     2101 tcttcattct tgtatccttg ggcagtatcg atatggcgat aacctgcagc cagcgcttct
     2161 ttaacagagg aaacagcgac atccccatca ggtgtttgcc atgtgccgaa tcctactacc
     2221 gggatttcgt aaccatttga tagacgataa gtgcttgtta atgaattcat actttcagct
     2281 ccttttttat tcgttcaact ataagtgtag cgcatttttc gaaaaaaaga atccattttg
     2341 tttctactct tgaaattttt gtttaaaaga aaatgatttt gattctggta tttttgattt
     2401 tttttccgta aactaagaca gaagggaatg agaaaatgga tatctattta aaaaaagcaa
     2461 ttctgcatat tattgacaga gaaactggtt ctccagtctt ttcacaaaaa gagctggatc
     2521 tgacaaaaga atatattcgt gattttcttc aaaagaagat ccaaaaaatc tcttctgctc
     2581 aaacaaaaac tggacaacta gcagaagaaa gcatgatcgt tgaatcactt aaaatcgctc
     2641 aagaaaattt tgtggaagca agtgaagcaa tcgttcagcg gtggttcgat atctaccaag
     2701 aaagtgaaga agcacctagt gcagatgtat ttgttgtctt gtatgaatta gatacagtga
     2761 tgtacttatc tttattgaaa gtcaattatc gtgaggctta cactcacttt gttgaagcag
     2821 acgaagcagg gatcgacaac cgcttgattt tgaatcgagc aattctaggg gcgaaaacac
     2881 aaaaagcaga tgaagcattc gctgtgaatt tgactgattg gacctacgaa ttaattgaaa
     2941 aaaaatatga gttttctggc aaaaaagagc tttatttttc tggaagagtg atcgaaagtg
     3001 ttcctgcacc ttctttagaa gaaaatgtaa aagtgatcca aaaagtagcc aagcatcttg
     3061 gaaaaaaatt tgagacagaa gaatttgata tcatggctga tttgaaagaa gctgtctatg
     3121 atacgataga agaaaaaggt cggttggatc atgagatgat tgcggaaaaa gtcttcaagg
     3181 aaaacatcac ggcaaaaatg gcttttaaag aagaagtaca agagcaagga tttgtcccag
     3241 aagcacctcc tgtaaaagaa gtacaagaaa tttctgagaa aaaatttgga aaacaaaaat
     3301 tcaagctatc aaacgggatc gaactgatcg taccagtaga tgtatatcgc aacccagatt
     3361 tgattgaatt tgtgaataat ccggatggta cgatatccgt gatgatcaaa aatgtggatg
     3421 aagtattgaa tcgtttataa aaatgactag aatattaggt gttcaagtac cagtgatcag
     3481 ttaaatgaat tgtgtcaaga gaaggatcgg aaaagacgaa tataacaaaa aaagagcgtg
//
LOCUS       DADLIO010000140         3345 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.149, whole genome shotgun sequence.
ACCESSION   DADLIO010000140 DADLIO010000000
VERSION     DADLIO010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3345)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3345)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3345
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.149"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            <1..781
                     /locus_tag="JOX41_002814"
     CDS             <1..781
                     /locus_tag="JOX41_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HAY6450491.1"
                     /translation="ELKFSIIQTWIDLKYNAITTWNNIKQFFKDTWKNIKDTAYNTWI
                     SIKNTMINTWNNIKDSFWNIVTGIVNSAENAWTNLKNGVSNAINRVKEIFNSLREVNL
                     FEIGKNIIDGLINGVKEKWNALKDTIKGIAGNIKNWIKGALDIHSPSRWMRDMVGKNI
                     VQGIIVGIDKEQSKLDQTMTNLVKTPSVQPVVNGISHLPITQTKQNISASETKEIHLH
                     LNVYGDLPDSMVRKITTKIKTELTRQMKRDAGAVGGTLYAT"
     gene            771..1511
                     /locus_tag="JOX41_002815"
     CDS             771..1511
                     /locus_tag="JOX41_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAY6450492.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYKNVTRKIECYYKAPSIDMVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     LIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNLEHQDQVTLFLDFP
                     FLYPGKNEIKWTKNIHSFEIMPRWWRKV"
     gene            1508..>3345
                     /locus_tag="JOX41_002816"
     CDS             1508..>3345
                     /locus_tag="JOX41_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450493.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCGIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLVEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRIIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     VLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFNSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGTI
                     GTTDSVGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWR"
BASE COUNT         1256 a          406 c          642 g         1041 t
ORIGIN      
        1 tgaattgaag ttttctatta ttcaaacttg gatcgattta aaatataatg ccattactac
       61 ttggaataat attaaacagt ttttcaaaga tacttggaaa aatattaaag atacggcata
      121 caatacgtgg atttctataa aaaataccat gattaataca tggaataaca ttaaggactc
      181 tttctggaat attgttactg gaattgttaa ttctgctgaa aatgcatgga caaatctaaa
      241 aaatggtgtt tcaaatgcta ttaatcgggt aaaagaaatc tttaattcgt taagggaagt
      301 caatttattt gaaattggca agaacatcat tgatggactt ataaatggtg taaaagaaaa
      361 gtggaatgct ttgaaagata ctatcaaagg tattgcaggt aatatcaaaa attggattaa
      421 aggagcttta gatattcatt ctccatcaag atggatgcgt gatatggttg gtaaaaatat
      481 tgttcaaggt attatcgttg gtattgataa agagcaaagt aagttagatc aaaccatgac
      541 aaatttagta aaaacaccgt ctgttcaacc tgtagtaaat ggaataagtc acctaccaat
      601 tacacaaaca aagcaaaata tatctgctag tgaaacaaaa gaaattcatt tacatttaaa
      661 tgtttatgga gatttacctg attcaatggt tcggaagatt accacaaaaa ttaaaacaga
      721 attgacaaga caaatgaaac gagatgctgg tgcagtagga ggaacattat atgcaactta
      781 agagaggaca attttttatt aatcaacatt attcttctga atttaatgtg tatattcaaa
      841 acaggcctgc ttctgtttca gctagtcgag taattgaatt gagagagcga gaaggaaatg
      901 attctatcat tattgataaa ggctattaca aaaatgtgac tagaaagatt gagtgttact
      961 ataaagcacc ttcaattgat atggtgcagg agtgggaaga tcgaatcact gaatggttag
     1021 atatgtcgtc ttatagtgat tttattcttt actatgatga acaatatatt tatcaagctg
     1081 tagtaataga aggacctgaa tttaaaggaa caagaaaaac aggaaatatt gtcccttttg
     1141 aatttacagt gagtattcga ccatttaagg aaaattacaa tggtagattt actattcgac
     1201 aaacagaaac ttttgaaatt tataacccag agaagtattc ttcaaaaccg cttattaaat
     1261 tgagtggttc tggagatgct tctttttata ttaataagga taaatatgat ttgaaatcgt
     1321 tggacagaga attatttata gattctaaat tagaagaggc ttatcgaaaa ttagatggta
     1381 atttagaaca tcaggatcag gtcaccttat ttttagattt tccattttta tatcctggaa
     1441 aaaatgaaat taaatggacg aaaaatattc attcatttga aataatgcct aggtggtgga
     1501 gaaaagtatg aaaccaagaa tatatagtcc tactgaaaca gatttctcaa cgaatggctt
     1561 aggaatttta aaggattgta caagatgtgg aatatatgaa gtagctaatg gaaaatatga
     1621 attagagttg gattatcctt taggaactag atttgatgaa tattttgaaa atgactatca
     1681 aataaaagca aagccaaacg atcaagaaga gtatcatatc ttttttattg atgataaaga
     1741 tatagatact tttttaaata cagtaactat ttatgctcag agtcgtacaa atcgacttgg
     1801 aagacgggta gtcactcttg tggaagtgga ctctaaaact ggtcaagaag cgatatcaat
     1861 tattgaaact aaaatggata aaaaatctga catacgactt tattctgata ttacggctgt
     1921 ttctagcaca atctttgaag cgagaaatgt tttaaattgt attgctggtg aacaaggatc
     1981 attgcttcaa tattggggcg gagaaattaa acgtgaacca tttaagcttt ctttgttaaa
     2041 gcgaagaggt cgcaataatg ttggaacgat tcggtatgga aaagatatgt ctggtttgaa
     2101 ggtcaaatta gattggacag gtataaaaac aagaattatt ccatatgctg atcctcaaag
     2161 tgaagtaggt acgactaatc gaatttatgg ttcgccagta gatagtgcct atattaataa
     2221 ctatcctgat gtctatacag aacatgttca gtttacagaa gaacaaggag taaaagacat
     2281 taagagctta aataaaatag ctaaaaatta ctttaaaacg atcaatcctg gctgtgataa
     2341 gcctaaagtt tctattacgg ttgaatttga taagttgact gatagtgaag aagcgaaaga
     2401 atttgcgaag attagaaatt atggtctgtt tgatacattt aaaatatatc ataaaaaata
     2461 taatatttat cttgaatcaa aggttagtgg actacaatac gattctttat ctgaaaaaac
     2521 tttgaaatta gaagcaggag acattcaagt tgctttttat cagcaacaag ctgtaactat
     2581 tcaggataaa ttaaaagatt atgcaacgaa taattatatg agtgatttta atgattatgt
     2641 ttcttcaatg attacaggtc aaggcagtgc aggaggatat gtagttttat ggccaaaaga
     2701 aaaaccttcc aacatcttta ttatggataa tccagattta gaaaaggcaa gagaagtact
     2761 aagaatgaat aaaaatggga ttgctttttc taagaaagga tggcgggggc cttttaattc
     2821 agcttggaca ttagatagta tatttaatgc caattttata caaactggat taatcaaagc
     2881 agatatcttt caaaattctt ttaacaagac tggagatgta ttgaaattag ttaatggact
     2941 actccaaatt tggaacaaca aaaagaaaat aatggagtta actaaaaaag gaatggaatt
     3001 ttggaattct aagggttcaa ttggaacgat tggaacaact gattctgttg gtaatccttt
     3061 tcctggggct tctactccaa cccctattga agataattct ttagttattc gtacaaatgg
     3121 agacggcaaa tatattttga tttctcctaa agtaggaaaa ggattagttt tattaggaaa
     3181 tggtaaagca atttattttg gagacttaga tgtacaagga aaacttacag ttaaaggaaa
     3241 agaaataatt cctggacaag gtggtggtcc atcgggaggt ggagaatcta ctggtgggta
     3301 tcctagtgaa ttaaaaacag atgcagaaaa gagagcttgg agaat
//
LOCUS       DADLIO010000141         3200 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.151, whole genome shotgun sequence.
ACCESSION   DADLIO010000141 DADLIO010000000
VERSION     DADLIO010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3200
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.151"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            301..585
                     /locus_tag="JOX41_002817"
     CDS             301..585
                     /locus_tag="JOX41_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450494.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            588..1004
                     /locus_tag="JOX41_002818"
     CDS             588..1004
                     /locus_tag="JOX41_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450495.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            complement(1141..1860)
                     /locus_tag="JOX41_002819"
     CDS             complement(1141..1860)
                     /locus_tag="JOX41_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAY6450496.1"
                     /translation="MDEKTELTVKYQNELNLVPLKNFNAKQMDLFFALCARMKDRGLK
                     KVRFSFEELKELSDYKMTATKAFVGDLEKLYKDMLNLTYRTEDEDSIRYFVLFTGFEI
                     NKTKKFVEVSVNPDLEYIINGLTAEFSRFELSAFTSLRSTYAKTLFRLLMQYRSTGYY
                     VVRIEEFRSLMDIPEYYQMGNIDQKVLNPALRELKKYFNDLKVTKIKAKKGNKIAKLE
                     FTFSSLTSDLPKISLRNWLEE"
     gene            2513..2608
                     /locus_tag="JOX41_002820"
     CDS             2513..2608
                     /locus_tag="JOX41_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HAY6450497.1"
                     /translation="MCFVFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            complement(2911..3156)
                     /locus_tag="JOX41_002821"
     CDS             complement(2911..3156)
                     /locus_tag="JOX41_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450498.1"
                     /translation="MRLEKEKMEKFPYEYFQNLEKLEQAIQAIKFDLTDEKLLEYKNM
                     TPERKRSLEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
BASE COUNT         1065 a          597 c          499 g         1039 t
ORIGIN      
        1 aaaaaaaatg tcgtttgaaa aactaaataa atttttgatc gtgcattttt aaatttggtt
       61 atcgattaca cgtgcagcac tcccccccga attttaaaga gcataaggaa acgtgtaccc
      121 actttctaaa aaaagtgggt agataggctg tgcctatcac gtttctcaga aaaaaatttg
      181 atatcacttt ttcgccatcg tgggtagctt atgtatagca ttttggcaaa aaacagctat
      241 acaaatatag tatttgtatg gtatacataa attatacata attgcaaaag gagatttttt
      301 atggacattt tagttcggaa tattgatcca aagtttgttg caacaataga caaacgttgc
      361 caagaactca cgaataaaac aggagaaaaa tggagtcgaa ataaatatct aaaagtttta
      421 atcgaaagtg attttgaccg tcaacttacg acttacaaaa aagaccaatt cgatttattg
      481 ctcgataaat ttattgctat ccaaacagaa aatactcaaa tattaagcga gtatgtctac
      541 acaaataatc aaatcattga aatgcttatc ggaggaatga tataaccatg agaaaaactt
      601 ctgtccaaaa acatgttact ttgtacccta gtcatgttga cgttttagat tccatcatcg
      661 aaaaaaatcc agatatcaat aactactcgg aagccattcg ctttttatgt atgagttatg
      721 aacccgatac caacacgacc actaccagca atcaggcaaa actaaatgct atgggaaaag
      781 aaatttccat catgactgaa atcatcgcag aatttgctga tttatatcta aaagatacag
      841 gcgttcttat tggcacaaat tctaaagtat atcaagaagt gaaagaaaaa atcgaagcta
      901 aactaaatcc atcaaatcga aatcgaccaa agaatcatca aaaagaaacc agtcaaacag
      961 tcacttctag aaatttcgac ccaacaaatt ttctaaaacg ataaaaaaca gataggagtt
     1021 attcctatct gttttttatt tagaagcccc atacaatatg ctagaatgta ctagcaatct
     1081 tagtcggttg taagggactt gtctacttgc ttaatgtaag gggggcgagt tcttttttat
     1141 ttattcttct aaccagttac gcagagaaat ctttggcaaa tctgacgtta ggcttgaaaa
     1201 agtaaattct aatttggcga ttttattgcc cttttttgct tttatttttg tgactttaag
     1261 atcattgaag tattttttta gttctcgtaa tgcaggattt aatacttttt gatcaatgtt
     1321 acccatttga tagtattctg ggatatccat taagctccta aactcttcaa tacgaactac
     1381 ataataacca gtagaacggt actgcataag cagtcggaat agagtttttg catacgtaga
     1441 acgcaacgac gtgaaagcag ataattcaaa tctactaaat tcagctgtta aaccattaat
     1501 aatatattct aggtccggat taacactgac ttcaacaaac ttttttgttt tattgatttc
     1561 aaaaccagta aacaaaacaa agtagcgaat agaatcctca tcttcagtac ggtaagtaag
     1621 attaagcata tctttataga gcttttctaa atcaccgaca aaggcttttg tagcagtcat
     1681 cttataatca cttaactctt ttaattcctc gaaagaaaat ctaacttttt tcaaaccacg
     1741 atctttcata cgagcgcata atgcaaaaaa taaatccatc tgcttagcat tgaaattttt
     1801 cagcggtact aaattcaatt cattttgata tttgactgtt aattccgttt tttcatccat
     1861 tcctttcttc cccccttaca aataaataat aacctttaac aaccaactcg taaataggtt
     1921 ggttgttatt atacaaaagg atattagtac tcagataaaa agttgttagt actcagataa
     1981 aaagttgtta gtactcagat aaaaagttgt tagtactcag ataaaaagtt gttagtaccc
     2041 ttctgtatcc gttgggagag taaggctcaa ctgcccccta aaaagggttc taaaaaatct
     2101 ttaaaaaata aataaaataa acgcgcgcgc gcgagcaaaa tttcccgcca aaaaatcacc
     2161 cactttttaa aataaacagg ttcgcgcatg atattaaact gccaatctag ctccctatgg
     2221 tcgctgtaag aaggagtgat cgctacgctc tcacatttta cttgcagcag tcgcctttag
     2281 gctccttcgc caaaaataat tcattaggga ctcctttgtg gcgtcctgag agctcgtcta
     2341 agccgttcta agacaagatt cgataaaaac tatgtccttc gttctaaagc gccttacagg
     2401 cggtcagggc aagccctaac aaccccaagg caataaaaaa cttaggctta tttttgcttt
     2461 tttattgtat aattgattgt cgcctatccg acagtcttgc gactggaagg aggtgtgttt
     2521 cgtgttcact aactttattt gctcccttct tgttgggctt ttaagcgctt tgttcagtta
     2581 ctggttgaat aaccgaaaca agaagtaaaa cttaattaag gcgactcagc ccacaaaaaa
     2641 agccccagag aatccgacct ctctggggct ttcgtgtgtt tcgtgttcac ttatttgcaa
     2701 tcaaattata acagaaataa atatttattt caaaaatatc ctacaaaagt ctaaaatccg
     2761 taattatttc ttatatgcaa catttacaaa taaagtcgct ctgagagctc gtatttttcg
     2821 atttaagacg ttttatttag tttttggtgt attttcattg gtccaagcta aaaaactctt
     2881 agaagcgatt ttagagccat ttaaacccac ttaattatat tctccatgaa attcgctcca
     2941 tgcgtcaaaa gctgcgtctg aaattccgcc gtcttcgttc actagttgca ttaatttttc
     3001 caacgatcgt tttctttcgg gtgtcatatt tttatattcc aacaattttt cgtctgttaa
     3061 atcgaacttg attgcttgaa ttgcttgctc taatttttct aagttttgaa aatattcgta
     3121 aggaaatttt tccatttttt ctttctccag tctcacaatt tttctagaaa taaaatcact
     3181 tctttgccgt ctatactctc
//
LOCUS       DADLIO010000142         3041 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.152, whole genome shotgun sequence.
ACCESSION   DADLIO010000142 DADLIO010000000
VERSION     DADLIO010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3041)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3041)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3041
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.152"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            138..752
                     /locus_tag="JOX41_002822"
     CDS             138..752
                     /locus_tag="JOX41_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAY6450499.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRL
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            complement(776..1126)
                     /locus_tag="JOX41_002823"
     CDS             complement(776..1126)
                     /locus_tag="JOX41_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAY6450500.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(1120..1383)
                     /locus_tag="JOX41_002824"
     CDS             complement(1120..1383)
                     /locus_tag="JOX41_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HAY6450501.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            complement(1724..1903)
                     /locus_tag="JOX41_002825"
     CDS             complement(1724..1903)
                     /locus_tag="JOX41_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450502.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
     gene            complement(2284..2991)
                     /locus_tag="JOX41_002826"
     CDS             complement(2284..2991)
                     /locus_tag="JOX41_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450503.1"
                     /translation="MNKVVYQLTTEDVSQFLTSKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYMESETSQTKVTVSHNHLDVYKRRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATVDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKGK"
BASE COUNT          925 a          589 c          469 g         1058 t
ORIGIN      
        1 atactatttc ctccatcatt agtttttgtc tatataaggt ataccctaac tagacacgac
       61 cgcgacattg aaaaatctgg ttttctcgtg tatgattagg gtgtttttta aatagttgca
      121 gaaagtaggt aaaaattttg agagttgcat acatacgtgt ctcatccatc gatcaaaatg
      181 aacaacggca gattgaagaa atgaaaaaat tcggtgcaga gagaattttc attgagaaac
      241 aatctggcgc aacgattact catcgacttg tttttcaaga agcactggat ttcgtccgag
      301 atcaagatat ttttattgtg gaagctattg atcgacttgg aagaaattac gacgagatca
      361 tcgcttcagt caattacttg aagaagaaaa atgtgcagct gatcatcaca agtctaccga
      421 tcatggccga agcaattggc aatcctctcc tggataaatt cattaaagat ttgatcattc
      481 aaattttggc catgatcgct gaacaagaac gtaccgaatc taaacgacgt caggcacaag
      541 gcattaagat tgcaaaagcg aacggtgttt ataaaggacg tcctaagcta tacagtgcca
      601 atgcaaaaga tccccaacgt cgtcttgttt ataaaaacat cgttgaggat ctaaaaaaag
      661 gtgttgcgat cgctaagatt gcaaaagact acaatgttac gagacaaacc gtatatagaa
      721 taaaaaaaga cagcatggtc aatcacgaat agttgatcat gctgctgttt ctattttatt
      781 tgcttacttt ttgaaaaact gttctaactt tcatcaataa ctcctcaact aaactatcat
      841 gcgctttttc caaaaaaata cactctctgg cttcataatc aattgtcgtt agttgatcta
      901 ataatacttt tcctgttgtc ttcatttcat attctgagtt tatatttaca tatagcggat
      961 agtttctagt tgtactagaa attggagcaa ctgtaacaac gttactataa tccgcaataa
     1021 tatcatgact taaaacaata taaggtcttt tacctgtctg ttcgtgtcca gatcgaggtg
     1081 ctgtattcaa taatagaata tcgccttgtc taggttttct caccattttt cattacctac
     1141 tgcttcacct aaattttgaa tcgtcacatg atttctttca tcagtgtaat tttcaaataa
     1201 ctgttcaatt gttaattcat tttctatatt agccgcttcg ataattagcc gcttctgacc
     1261 gtttacttct tcttgtatta tcttcacttt gtcttctgta tgaattccaa gatattccat
     1321 aatatacttt ggcaatctaa ggccattact atttccccat ttttttatag gtaacatttc
     1381 catagtagac acctctttct gtatatacat agtataacat acataagaaa aaacgtatat
     1441 acttaattat ccttttctat taaattagat taacattcca tgaatccata aactatgtta
     1501 acatttatat gaaaatagtc gaaaggaaat cataatatgt ttaagaaaac aaaatcttta
     1561 gaatcaggta agaaaaaaat tgatctaaaa ataatctctt ctggatactt taaagatttc
     1621 atagttattg atacaaaatg gaataaaaag gacatagaaa atattctaaa tagtaggaac
     1681 aattaagtgc tatcactttt gtttcttcaa atgaaaagtg acgtcacttt tttagtgctg
     1741 gtatatcaaa tcctgctttt tcttgcgcga tcaatagatc taacgcaata cacataatct
     1801 tagattcact ttttccgtac ttctgcttta gttgctgcaa ttctttttgt ctcttttcat
     1861 ctaatgtcac gggtaaccgt ttatttccta ttgcaattgg cattagtact ctctcctttc
     1921 atcgaaataa ccctatgaaa aatatggctg caatcatctt gaatagtaga ctcacaaggg
     1981 ctaatacaaa tcgccaaaag atcaaacaaa ataccagtat tcctaagaat actacgaagt
     2041 ttaaatgtac agctgcagca tgacgcataa gtatctcgcc aacaaacagt acgaacaata
     2101 gaggaatgat tttattcata tggatctcct tctttctctt aggttatcgg gctttgcccg
     2161 cttatttcgc accacctaag cggcgggggc ggttggagcg attggtgcga aataagaacc
     2221 attcccttaa tttcaaggtt ttttgttctt atttcacaca tcctcacttt tcggtataaa
     2281 tggttattta ccttttttcc tttcaaatcg ttgatatggc attcgtttac ggtcaagttc
     2341 attttggatt tcttctgtat cgtcgtaagt gtaggtgtct aaaaaatcag ttaaagtcgt
     2401 gtaccagtcg tcgcctgggt tatctacttc ttctacatat tccctcaaaa atgcttcggg
     2461 tacagcgagt tcataatcca ttcccattaa cacgatagat tccgtcccac acgtcaaaaa
     2521 cctagtaaat acaaggtaat aatcgtctac cgtcgcattt ttgctgttta gctcttccat
     2581 ttcttcttcc attaattcca tgctctcgaa aattgaataa tattctgatt ctgagtaata
     2641 gtgtttccta caaatcgtgt agctgacaaa gttttcgacc agctcactcc tttctaggta
     2701 cacattcatg atgtattttt ctgtttctag tcgtagaagc tctgttcctt tttttaccgt
     2761 ttcaggacga cgtttataca cgtctaaatg attatggctg actgtgacct tcgtttgact
     2821 tgtttcgctt tccatataca actgttcttc cactctttga ataaagtact tcatttcttc
     2881 catacaacta aagtcttttt gaatccgtct gattacttca ttcaagtgtt ctttgcttgt
     2941 taaaaattgc gaaacatctt ctgttgttag ctgataaacc accttattca ttatctttct
     3001 cctccgattc aatcgtataa aatgcaccat ttttttcgat a
//
LOCUS       DADLIO010000143         3037 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.153, whole genome shotgun sequence.
ACCESSION   DADLIO010000143 DADLIO010000000
VERSION     DADLIO010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3037)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3037)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3037
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.153"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(25..960)
                     /gene="murB"
                     /locus_tag="JOX41_002827"
     CDS             complement(25..960)
                     /gene="murB"
                     /locus_tag="JOX41_002827"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HAY6450504.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(1033..1953)
                     /locus_tag="JOX41_002828"
     CDS             complement(1033..1953)
                     /locus_tag="JOX41_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAY6450505.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            2066..2818
                     /gene="xth"
                     /locus_tag="JOX41_002829"
     CDS             2066..2818
                     /gene="xth"
                     /locus_tag="JOX41_002829"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HAY6450506.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
BASE COUNT          856 a          612 c          526 g         1043 t
ORIGIN      
        1 acttatttta agttccatta cttattaatt ggctaaactt ctgcttgttt ctgatattgc
       61 ttgtttttct ccaatgatcc gcacttctgt ttctaaagac acatcaaatt tttctttgat
      121 tacttcttgg atgtgcgcaa tcaattcaat ataatctgtc gctgtcgcat gatcgatatt
      181 gacgatgaat ccagcatgtt tttcagagac ttgtgcaccg ccccatttca ggccttgcaa
      241 tcctgcttgt tggatcagct gacctgtata gtgtcctact gggcgcttaa agacacttcc
      301 gcatgaaggg tattctaatg gctgttttga ttgacgcaat tcggtcaact catccattct
      361 tgctttgatt gcttcataat cccctgtttg caaactgaat cgagcttcca atacgatagc
      421 acgtaattct tggactttac tgtgacgata agaaaatacc atttcgtctt ttgtcaaagt
      481 tttcaatgtt ccatcttcaa gcaaaagatc cacttcagca aaaacatctt tgatctctcc
      541 gccatacgca cctgcattca tataaaccgc tccaccgaca cttcccggga tgccgcaagc
      601 aaattcaaat ccagtcaatg attctgccaa agctgcataa gtcgtatcaa tcagtgaggc
      661 acctgcttcc gcaatgacca tcgttccttt gacatgaatc tgtttcattt cagtcagcat
      721 gatgactaca ccgcgaatcc cgccatcttg aacgatcaga ttgcttgcat ttcctaatac
      781 catccaaggt atatcatgga ttcggcaata atcgatgatt tgctttactt cttcttgttt
      841 tttcgggaat gcaaggacat cagctggtcc acctgttttc gtaaacgtat agttcatcaa
      901 tggttcatca aacaatatag taatcgtggc taagctttca actatttctt ctttattcac
      961 tgaggatttt cctttctttt ctcaaacgtc ctcattattc tatcacgctt aatacaatct
     1021 tgccagtctt gttcaaagtt gatgacggta gtgatcttta agcacttcct cacataattc
     1081 atgacttctt acaacttctt tttgtttaag caattctgtt tccgatttac ctaaacggat
     1141 ctgagaaaag aaggcctcta ccattggctc aaacccgcgt ttgactagcg tgtttgtcca
     1201 gtcgccaaat tctttcactt tttttccatc agcatcttga atgacaagct gggtcagatc
     1261 gtttacttca taagtaccat ttttacttgt tacttgatat ttttctatat tagcgccact
     1321 tgctaaatcc atcgttaaaa tagccgtttg attttgtgtt tctaattgta aaatggcata
     1381 ttccaaaaat tcctttgttt ctcttatctg gtattttgtt ctcaaaatgg gttcatctaa
     1441 taaatacaca gctgtatcaa taagatgtaa aaacaaatca taaaggacga actctgtcgt
     1501 ttcttttgcc gctattcgat ttttttgcag gtggatcaac cgcttatctg ggatacgttt
     1561 caattcttct accataggag caaagcgccg gttgaaaccg atcatcaaaa ttatttggtt
     1621 cttatcagct aattcttgca attcacgaac ttcatttaga tggacactca gtggtttgtc
     1681 aatataaaca tggataccat tttctagaca ttttttggct aattcataat gtacttttgt
     1741 tgctgcgtgg atcatacatg cttcgatttt ttcttctaaa agctcatcga tcgtttcata
     1801 tagatgttgg aacccgtact ctttttgaat tctttctttt gtttctttat ttcttgttgc
     1861 aaaataaaaa tcaagtgttc cttgtttttt cgcataagtt ggtaaatatg ctttttctgc
     1921 gatattccct acaccgatta caccaatctt catctacttt cctcctggat catttagtta
     1981 ctttcatctt acaccatttt ttactaaaat gaggtacaat agtatcgcaa aggtaaggaa
     2041 attaattcga aggagtgtgc ttttattgaa atttatctct tggaacgtaa acgggcttcg
     2101 tgccatcgta aataaaaatt ttttagaagt ttttcatgag ttagacgccg attttttctg
     2161 tctgcaggaa acgaaactcc aagcaggaca aattgattta gatcttccag gttattatca
     2221 atattggaat tacgcggaac gaaaaggcta ttccggcaca gcgatttttg ctaaaaaacc
     2281 agcattgaat gccacttacg gaatgggtat cgatatccat gatacagaag gccgtctgat
     2341 tactttggaa tattccgatt tctttcttgt aacctgttac acgccaaatt ctcaaagcga
     2401 attaaaacgt ttagattacc gattagaatg ggaagaagcc ttttataatt atttggaaaa
     2461 tctaaaaaaa caaaaaccag tcatcgtgtg tggggatcta aatgtcgctc atcaaaagat
     2521 tgatttgaaa aactggaaaa cgaatcaaaa aaatgctgga ttcactccag aagaaagagc
     2581 ggctctttct cgactgttgg ataacgggtt tatcgataca ttccgttatt tttatccaac
     2641 ccaggaaggt gtctactctt ggtggaacta ccgattcaat tcaaggaaaa acaatgctgg
     2701 ttggcggatc gattactttt tgacgagcaa agatttagag ccaggactag ctgatgcaaa
     2761 gatccatacg gacattatgg gcagtgatca ttgtccagta gaattagatt tgaaataaag
     2821 aggttgtgaa aaagtcgttt agtttcgagt attaagaaaa attttgtgaa aatggctttc
     2881 cacattttgc ataaatttgg cataataccg agaaactggc ttttgaacac tgtttatcga
     2941 gagattgtga aaaagctgtc ctgcatcaag taataagaac agccaaacaa aaatagttcc
     3001 tcatattttt cgtttggttg ggcttattac cgcagat
//
LOCUS       DADLIO010000144         2929 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.154, whole genome shotgun sequence.
ACCESSION   DADLIO010000144 DADLIO010000000
VERSION     DADLIO010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2929
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.154"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            127..981
                     /locus_tag="JOX41_002830"
     CDS             127..981
                     /locus_tag="JOX41_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAY6450507.1"
                     /translation="MEKEKLKILEELRRILNNKNEAIIILNNYFKGGVGKSKLSTMFA
                     YLTDKLNLKVLMIDKDLQATLTKDLAKTFEVELPRVNFYEGLKNGNLASSIVHLTDNL
                     DLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIIIDTVPTPSVYTNNAI
                     VASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFVPYLVDTDSATIKSN
                     LEELYKQHKEDNLVFQNIIKRSNKVSTWSKNGITEHKGYDKKVLSMYENVFFEMLERI
                     IQLENEKE"
     gene            1073..1288
                     /locus_tag="JOX41_002831"
     CDS             1073..1288
                     /locus_tag="JOX41_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HAY6450508.1"
                     /translation="MIVGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIET
                     AKNGGNVKEVMDQALEEYIRKYLPDKL"
     gene            1306..1578
                     /locus_tag="JOX41_002832"
     CDS             1306..1578
                     /locus_tag="JOX41_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAY6450509.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILTKEKVA"
     gene            1580..2443
                     /locus_tag="JOX41_002833"
     CDS             1580..2443
                     /locus_tag="JOX41_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin zeta"
                     /protein_id="HAY6450510.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAISEETQGNVVIIDNDTFKQQHPNFDELVKLYEKDVVKYVTPYSNRMTEAI
                     ISRLRDKGYNLVIEGTGRTTDVPIQTATMLQAKDYETKMYVMAVPKINSYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQPPTP
                     PIPKTPKLPGI"
BASE COUNT         1160 a          464 c          510 g          795 t
ORIGIN      
        1 gagggctttt atatattaat cacaaatcac ttatcacaaa tcacaagtga ttaatcacaa
       61 atcacttgtg atttgtgatt cttaatgata caatattact atacaaaaaa agaatggggc
      121 gtagttatgg agaaggaaaa actaaaaata cttgaagaat taagacgtat tttaaacaat
      181 aaaaatgaag caattattat cttgaataat tactttaaag gtggtgttgg aaagtccaaa
      241 ttatcgacta tgtttgctta cttgacagac aaattgaatt taaaagtttt aatgatcgat
      301 aaggacttac aggcaacatt gacaaaagac ttagcaaaaa cttttgaggt agaattgcca
      361 cgtgtcaatt tttatgaagg cttgaaaaat ggaaacttgg cttcttctat tgttcatttg
      421 actgataatt tagacttgat ccctggcacg tttgatttga tgttactgcc aaaattaact
      481 cgctcatgga cttttgaaaa tgaaagtaga ttgcttgcta ctcttttagc acctttaaaa
      541 agtgactatg atctcattat tattgatact gtaccaacgc caagcgttta tacaaataat
      601 gcaatcgtgg cgagtgatta cgttatgatc cctttacaag cagaagaaga aagtacaaac
      661 aacattcaaa actatatttc ctatttgatt gatttacaag aacaatttaa ccctggacta
      721 gatatgatcg gttttgttcc ttatttagtt gatacggaca gcgcaacgat aaaatcaaac
      781 ctggaagaac tgtacaagca acataaagaa gataacttgg ttttccaaaa tattatcaag
      841 cgaagtaata aagtaagtac ctggtctaaa aatggaatta cagaacacaa aggctatgac
      901 aaaaaagttt tatccatgta tgagaacgta ttttttgaaa tgcttgagcg aattattcaa
      961 ttagaaaacg aaaaagaata gaatcacaaa tcacaagtga ttaatcacaa atcacttgtg
     1021 atttgtgatt gttgatgata aaataagaat aagaagaaat agaaagaagt gagtgattgt
     1081 gggaaattta ggcgcacaaa aagcaaaacg aaatgataca ccaatcagtg caaaaaaaga
     1141 tataatggga gataagacgg ttcgtgttcg tgctgactta caccatatta taaaaattga
     1201 aacagcaaaa aatggcggaa acgtaaaaga agttatggat caagccttag aagaatatat
     1261 acggaaatat ttacctgata aactttaaaa aggagtgaaa atgaaatggc agttacgtat
     1321 gaaaaaacat ttgaaataga gatcattaac gaattatcgg caagcgttta taatcgagta
     1381 ttaaactatg ttttgaacca tgaactagat actaaaaata ctcgtttact agaagtgaat
     1441 cttttaaatc aattagaagt ggcacaagaa gttgatttat ttcaacaacc atttgaagaa
     1501 ttacaagcta ttcatgagta ttggcggtca atgaatcaat attcaaaaca aattttgaca
     1561 aaagagaaag tggcttaaca tggcgaatat tactgacttc accgaaaagc aatttgaaga
     1621 tcgtttagaa aagaatgttg aacgactaac taaaaataga ctagcggttg aatcgccaac
     1681 cgctttttta cttggtgggc aaccaggatc aggtaaaact agtttgcgat cggcaatttc
     1741 cgaagagaca caaggaaatg ttgttatcat tgataatgat acgttcaaac aacagcaccc
     1801 taattttgat gaactagtga aactttatga aaaagacgta gtaaaatacg ttacccctta
     1861 ttctaatcgc atgacagaag cgatcataag ccgtttgaga gataaagggt ataatttagt
     1921 gattgaaggt acaggacgaa caacagacgt tcctattcaa accgcaacaa tgcttcaagc
     1981 caaagattat gaaacaaaaa tgtatgtcat ggcagtacct aaaatcaact catatttagg
     2041 aacaattgaa cggtatgaaa ctatgtatgc agatgatcca atgacagcca gggcaacacc
     2101 aaaacaagcg catgatattg ttgtcaaaaa cttaccgacc aatttagaaa cccttcataa
     2161 aacgggctta tttagcgata taaggcttta caatagagaa ggagtgaaac tctattcaag
     2221 cttagaaacg ccttccatta gtccgaaaga gaccttagaa agagaattaa atcgtaaagt
     2281 atcagggaaa gaaattcaac cgactttgga gagaatagag caaaaaatgg ttcaaaatca
     2341 acaccaagaa acccctgaat ttaaagcaat tcaacaaaaa atggaaagct tgcagccacc
     2401 tacaccacca atacccaaaa cacctaaact tccagggatt taaaccttaa aaaagtaaaa
     2461 gagtagttac caaaaaacgg taactactct ttttttataa aaacatttcc tcatttttta
     2521 aaagctgatc gagaaataaa gcacacaact gtattctttc ttttttcagt tggtacattt
     2581 tgcagtctgt aacgtgccat ttactgtttg ttaccttaac atatccagtc gaaaacacaa
     2641 gggtatataa acgagcaagc tcgcccttgt gttttctttg tgtctatgtt gcgttctcgt
     2701 cacagcaaac gacacgaaca cactggcgaa aatgaaccaa caaaacgaaa aaagaaagga
     2761 gcgtacactg taatttattt ctagctttta aaacatgagg aaaacagctt cacttcctca
     2821 aacgcctaac aaaaatggtt gtcaaaaaac taaaaatcaa aaaaagaaaa gaggaaaaga
     2881 aaatggaaaa aacaaaaaaa ttacaattag aagattttac agaaaatgg
//
LOCUS       DADLIO010000145         2740 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.155, whole genome shotgun sequence.
ACCESSION   DADLIO010000145 DADLIO010000000
VERSION     DADLIO010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2740
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.155"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(<1..302)
                     /locus_tag="JOX41_002834"
     CDS             complement(<1..302)
                     /locus_tag="JOX41_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HAY6450511.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLW"
     gene            661..915
                     /locus_tag="JOX41_002835"
     CDS             661..915
                     /locus_tag="JOX41_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAY6450512.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            916..1233
                     /locus_tag="JOX41_002836"
     CDS             916..1233
                     /locus_tag="JOX41_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAY6450513.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1792..2727
                     /locus_tag="JOX41_002837"
     CDS             1792..2727
                     /locus_tag="JOX41_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450514.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          968 a          390 c          510 g          872 t
ORIGIN      
        1 ttccaaagaa attgtttgac tcttggaaag tcacgtttta tcaatcttga gctggcactt
       61 ttataggcat tgatgaattt tgtcaattct gttttaggtt gagctttgaa cataatatga
      121 acgtggtctt tatcatgatt ccactccact aaagtaatgt gatacgattc tgaaattctt
      181 tcaaaagtag ttttggcata atcagatatt tcatcatcaa tcacttgtct acgatatttc
      241 gttactaaaa caaggtggta ataaagaaga aatactgaat gattatttgt atctaattcc
      301 atgttatatc aactcatttc ttgtatagac tgattgtaac atgggacaaa ataaaaaggc
      361 aatacgcctt agttgtcggt cttcgagtta ccaacggtaa ccctcatacc gaacggcatt
      421 catcacccac ctatagagga tgggcgactt ctgcctaatt ctgttaaatg gatgttaacg
      481 gaagtgtatg gtgagtagtt cactcgtatt ttgatatcgt ttgtatatgt tttcagcgtt
      541 ctaagtggct tattttgtcc aataataata tggagtggaa tcccttaaga aacaccgttg
      601 gcaattgttg ttataacatg ttataattta ttcatcaaaa actaaaagga gtgtgataac
      661 atgggaaaag aactaaaggt tagaaagatc ggcaatagcg tgggagtgat ccttccaagc
      721 tctcttggat taaaaagcgg agacattatc caagccaaac aagaaggcaa cttattcata
      781 ttagatacta ctcaaatagc aaaagaacac gatcgcaaat tgattgaaga aagtttccaa
      841 gactttgaga aaggtttaac agtttcagaa attgaaatgg taaaagcttt cggaaaatac
      901 ggctggagtg aatagatgaa agagtacacg ctagtttatt ctaaaagttt tcagaccagc
      961 cttgaaacga taatagaaga atgggaaaat gagcttgctc tttctccagc cagcataaaa
     1021 agatttgtag gtgcgatcca gaaggcttta gaactaacca aaaattttcc aactatgcat
     1081 gaggaagttt ccgaaatcta tggaatggat atcccaacat atcggatcgt gatcggcaaa
     1141 agctatgcct tattttatcg gatcgaccat gaaaaaaaag agatacttgt aggacgtatt
     1201 ttccaatcta aacaaatgaa actaggcttt taacaataat taggaaaaag tcgctcatcc
     1261 tctacaggtg ggtgattaat gccgctcgat atggttgtta accgtcggtt actcgaagat
     1321 tgatatataa gacttagtac ctttttattt tgctccatgt tatggccgaa ggtctaaaga
     1381 tacaatcatt agtctagaga aaaattaaga accgtaggaa ctacggggat cgcttggtga
     1441 ataagagaca ctgctattag tgaaaaaata agatatcaag tacgctctat tcccaaaaat
     1501 ttcgtgactt tactcatgag aggttcaagt agtatatttt taatcaaaat tgacgtaact
     1561 tttaataaat actacctaaa taaggtagta tttatttttg tgttttaaaa gaggaagtcc
     1621 aatatatcta tgggaaactt cttaaatatt atgttggtac atgaaaatat acatccctgc
     1681 tagactattt acaacatttt actttgtacg tattcttgtt ttaaaaggaa tgggataaaa
     1741 tataggtaca ataactattt gatgctaaat ataattaatg gaggagagat agtgaacata
     1801 cttaatgaaa aaagatatgt atggtttgct ggtaaaaaat atattactac tttcaaaaga
     1861 ttatccgagt taatgcagca gactgttaaa agtgctatgc ctgaaggata caagtttaat
     1921 tttgttcaat cttcagtatc tactgaaagt atctattttt caattctttc tgagagtagg
     1981 ctttttcatt ttagaataag ttctcatgta aagaaaactg atgttgatat atatacgttc
     2041 cgtacaaata attataaaaa tttaaatgat ttgagtagaa gtatcagtga atatctcaag
     2101 gggaatagct atctcaagat tcgattttca catatattaa ttttactacc atatttgaat
     2161 gagaatttca ccctaattca agtagataag tctttcattg cctcaggtaa tcaaggaaat
     2221 atgaatatta caagtaacaa aacgtcacgt gtgctattgg cgttgatggg ttacggaatt
     2281 ctttatagag atgaccaaaa tggccagatt ctaataaatc gggctgggcg ttcattatta
     2341 atgaaatata gaaaatttat accggaagat tttcaaaact tacagttaga aaacatgcgt
     2401 ttagaagatt tatttagatt agcagaagat gataagtata gatttgaagt tttgaaaatt
     2461 caaaagaatg aactattgaa taagttatat cctgagaatg cgataaaagc acattttggt
     2521 gatgctaatc atatgtatag ttggttcatt cctaaaagat ttagagggaa aatcaatgct
     2581 ggagatcaag tgaaagtact caatcgaaat agtacagatg tcgtaatgat aacagatatc
     2641 tatgtagaag atgaagatat aatcaaatat atgaagcctg tgataaaact tgttaataaa
     2701 aataaaggaa cccgtggtgc tagttaattt tttcctagag
//
LOCUS       DADLIO010000146         2602 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.156, whole genome shotgun sequence.
ACCESSION   DADLIO010000146 DADLIO010000000
VERSION     DADLIO010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2602
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.156"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(126..416)
                     /locus_tag="JOX41_002838"
     CDS             complement(126..416)
                     /locus_tag="JOX41_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450515.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFFLNKK"
     gene            complement(534..794)
                     /locus_tag="JOX41_002839"
     CDS             complement(534..794)
                     /locus_tag="JOX41_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450516.1"
                     /translation="MGVDHLIVLSKLLFWIPFIIMTSAFFYLFKRPNKYLLLSACPMI
                     YFIHKIRGFYYYDSGISLFCYEIGLLASAIFFIFVLEYFRKK"
     gene            complement(931..1344)
                     /locus_tag="JOX41_002840"
     CDS             complement(931..1344)
                     /locus_tag="JOX41_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HAY6450517.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1800..2285)
                     /locus_tag="JOX41_002841"
     CDS             complement(1800..2285)
                     /locus_tag="JOX41_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450518.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2424..>2602)
                     /locus_tag="JOX41_002842"
     CDS             complement(2424..>2602)
                     /locus_tag="JOX41_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HAY6450519.1"
                     /translation="VGGLNWLLVGLFELDLVAMIAGGSTTIFAKIIYIVVGICAIYCL
                     KFFPMITRKVDERY"
BASE COUNT          963 a          434 c          402 g          803 t
ORIGIN      
        1 aataacataa taagaaagta aagtggattg atttgagatc tttttatact tcaaaaaaga
       61 taacacccaa ctttcaaaaa tatgttttgg aagttgggac aaacgagtta atacatttta
      121 atacattatt ttttattcaa aaaaaatagc acaatggcaa agatcgtaag agagatcata
      181 agccccaatg aatgactaaa aagaaaagca gaatcacatg ccatatcatc ccatatttct
      241 tcaagaaaat aaataagcgg gaaaaaggga aggaatagta gaacatcgat ccagcaccat
      301 ttttttcttc ttttgaaata acataaaaca ataaacatga acgtgcaggg aagtaaaaac
      361 aaagctttac tcataactaa caaaatacca gctcctttta tttttttctc ccccacattc
      421 aaagagtaac aatggtatgt acttaataat agaaaaatgg atcaacttgt atgaataaca
      481 gctgaaaaga tctgcaccaa ataaaaaact tccagccaaa actgactgga agtttatttt
      541 tttctgaaat attctaacac aaatatgaaa aagatggccg aagctaataa gccgatttcg
      601 tagcaaaaca atgagatacc agagtcgtaa taataaaatc ctctaatctt atggataaaa
      661 tagatcatcg gacaagcaga taagagtaag tatttgttag gccttttgaa taagtaaaag
      721 aaagcactgg tcattatgat aaatggtatc caaaacaaaa gtttacttaa gacaatcaaa
      781 tgatcaactc ccatattttt taccaagaga gatcataaca tctttatcgt aaaaacaaaa
      841 tatttttttg ctcattttga aaatttaaac atactcgttc ttatccaaat atataaaaat
      901 cgcccctcat tcatcgagag gcgataagtt ctaatttaac tcaatttttt ttgtttcttt
      961 tggctgataa gctgttttag gtaataccaa tttcagcaca ccgtttttaa aggttccagt
     1021 gattttttct tcatcaacat taggaagata gaatgaacgt ttgtaagaga ccgaatgtct
     1081 ttctttccgt acatagttgc catcttcttt atcttctgta tgggactcat gattggcgga
     1141 gatcgtcaaa gtattatctg aatattcaac tgtcgtgtct tctttgtcac agccaggcat
     1201 atcagcagtt agtttgtatt ctttttcatt ttcgactaaa tctacttttg gataacttga
     1261 aacacctaaa aaatcattga atgctggact aaacacgtca ttgaaatcag ggaacatgtc
     1321 gcgaatgcta ggtacatttg ccatttttga tcatcctttc aataagtatt ttttatttat
     1381 ccctatttac gtaataactc tattttgaaa aaaatgcaag tataatggtt agctttgtga
     1441 atatttcatc taatacgata caaaggctat ctttctaatt tgaaaaaggg atcattaaaa
     1501 taataagaag aaaatatgtc aaaaggtaaa aaagtaaatt cttctatcca aatatagaaa
     1561 aattgaatct agaaaaccgc ccgacaataa atttcattaa ctcagttgac cgaaaatgaa
     1621 gtagatacca aaaatttatc aagagagcaa gtagagaagt gagtatattc ataagagaaa
     1681 tagctgtaac gaattattag gttaatgcaa atgcttattt atactccgta taactttctc
     1741 agaaaaaatg ataccaataa tgacttgcta gtactgtaaa tccgtataat atcatctaat
     1801 caaaatggtg ttccatttgc atctgtcatc gtaatcgatc cttcgggtga cactcgataa
     1861 aaaccaacgc ttccagatcc tccttgggaa cggatttgtt tgctggaagc tgtgaacaaa
     1921 taatctcgat caattttttg ataaaagcta ataacaatat cgtcactttg taattcggaa
     1981 cggtgggcaa taagaaatag aagtgctttg tcagagtttt ctaatggaag agaaggtaca
     2041 gtgctttctt gcatttcaga tgttgaagaa atgctaaacg actgaatact tgattggcta
     2101 tgttgcgaat ctacattacc agtagaagta ttagtaatgg aagtagtaga agtactttta
     2161 gttgaaccaa cctcagttgt tgaaatggct gctgaagatt ctttaacaga attctttgtt
     2221 ttatatccac aggcagaaaa aagtattaca gttcccaaca agcctgcgta aatcccttta
     2281 tgcatgatag ctcctcctaa aatagattat ctttattcag tatatcactt aaacaaagaa
     2341 aagcagatgg tttaaaatga aaaaaccttc ccaataaagg gaaggttcat gaagataata
     2401 acttttttaa taattatagc tttctaatat ctttcatcaa cttttctagt aatcattggg
     2461 aaaaatttca agcagtagat cgcacaaata cctacgacga tataaatgat cttcgcaaaa
     2521 atagttgttg aaccaccagc aatcatagct actaaatcaa gttcgaacaa gcctaccaac
     2581 agccagttca accctcccac aa
//
LOCUS       DADLIO010000147         2532 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.157, whole genome shotgun sequence.
ACCESSION   DADLIO010000147 DADLIO010000000
VERSION     DADLIO010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2532)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2532)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2532
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.157"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            12..224
                     /locus_tag="JOX41_002843"
     CDS             12..224
                     /locus_tag="JOX41_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450520.1"
                     /translation="MIFQGVITLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIIL
                     SFLVNAIVLFLYVLNYLDINPLIFSR"
     gene            388..642
                     /locus_tag="JOX41_002844"
     CDS             388..642
                     /locus_tag="JOX41_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450521.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            712..957
                     /locus_tag="JOX41_002845"
     CDS             712..957
                     /locus_tag="JOX41_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAY6450522.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            1033..1398
                     /locus_tag="JOX41_002846"
     CDS             1033..1398
                     /locus_tag="JOX41_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450523.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(1459..2022)
                     /locus_tag="JOX41_002847"
     CDS             complement(1459..2022)
                     /locus_tag="JOX41_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450524.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
BASE COUNT          747 a          454 c          402 g          929 t
ORIGIN      
        1 tgtttattgg aatgattttt caaggtgtga ttaccctttt gcttcttgtc atgatgctca
       61 gctataaagg aaaaagatat gcccgtattc aaacaaaagt atttgttaaa tatgtttcca
      121 ttcgctatgg gatcatcatt ctttcctttt tagtgaatgc gatcgtcctc tttttatatg
      181 tattgaatta cttagatatc aatccattga ttttttctcg atagataaga cacattcagc
      241 ggaacagttc ctgcttatca gcagaaaact gttctgcttt ttcatttttc attgatctat
      301 tcttctttta ttttcctagc atttcatttg tgatgtatgc aataacatgt tatcttttat
      361 tatatgaatc gttgaggagt ccgttacatg attacgttgg tgagagtttt gttttgggtg
      421 cctgcggtcg cactggtcgc aagtattgtt tatcttatga attggaacaa agaacggttt
      481 tatttagcta ttttgactct tccggctatc tactttatgt ggaaagtttt taattacaac
      541 tactttgaac ccgatagtgt ttttatagaa gaattatcag gactggtttt gtctttattg
      601 atcgtcattc tttatttgat acgtttaaat aaaaaacatt gagtactatt gattgcatgt
      661 gtagctttct atagtcatta taactattct actataatga aaggtgatta aatgagtatc
      721 gaagaagcta ttttactgga tactttacgt tgtcgtctga atttcttaag aactggccga
      781 tctttatctc aagtagctgt ttctagcgcg ttaagtattc ctttattcaa atatcgtaag
      841 tacgaagaag gagaagaaat tccaagcatc attgaattaa tctatatcgc tgacttttac
      901 gatatttccg ttgattacct aattggtcgc tcagaaacag caagcaaact gaagtgattt
      961 tttccagcct tggtgctggt tttttcattt aacgtctaag gttaacaatc tatatataaa
     1021 ggagacattt ctatgcgatt atggcatgaa aaattgattt caaagcttcc tcgtcaacag
     1081 cttttaggac aacatcggga atgctgtgca ttaagaggaa atggctgggg aaagaaacat
     1141 gctactgtgg attatgtttt tcactattct ccttatagat tattccaata tcatcagctt
     1201 gtcatggatg aaatggaaaa acgtggttac agcccagcac cagagtggaa aaatcctatg
     1261 tatcgtggca aatcatgcga agcatttttt gatttaccta ctgtagagcg caacgtgccg
     1321 atttatccgg aacacgatga agtttatcta gcagaatgtt tagcaaattt ggagcaaaaa
     1381 ggaatttatc ttacctaata taactagaaa agccttctat ctcctcttac ttcattaaaa
     1441 agctttaacc atcttagatc aagctaaaat gtcgtaagtt ttagggttat cttcatcctc
     1501 acgtgcaaaa ctaaaagcgt actctagttt tggttcatcg ccaacttccc tagacataaa
     1561 tgaacatctc ctgacgtggt ttaaaagtac cgcatcttcg acgtctgtat acgatgcaca
     1621 gcacagattg cttcttttga tctttctttt gatttttctg ttgcttcttc tacaccttct
     1681 tcgattacta catcgatgct tacaattgct tctgcctaat attcccatgc atcgtcgatt
     1741 taagcctctg tagtcactgt gatcgtttcc acattttaac tcctctgtcg tggcttcagt
     1801 tgattttgtg atcagttcag ttgctaagcc agagtcagaa caacctgcca ttgctagcgt
     1861 taatattgat agtaaaaata gtttttttat cataaggttc cccccctgaa aatagactaa
     1921 aataataacg ctttcttttt ttgttttcag acgaaaatta ataatttcta aatattcttt
     1981 aaaaaagctt ataactatta tgcctttttt aatatataac acagttattt ttaaaaataa
     2041 gaatgctaaa tcactctaca ataacggcga aagcacaaaa aataaaaaaa ttattacgtt
     2101 attaaaaaaa cagatgaaag atcaggtttt attagatctc attctttcat cacttgaagg
     2161 gatttaatga actacttttt cctctttgtc gtttttatat attcgtattc cttcaaacag
     2221 taggatagcc tctttcaatg cttgatattt gaactgtccg ttacttaaaa atttagatgt
     2281 gccgccctct tcctagaaca tattcttttt tactttttca ttaattgaca gaccaatcga
     2341 acgaaactgt aaatttcgat aggataatga ttggtcaaac tcattcattt tcaagacatc
     2401 tcgattcata ttcaagatag gaatcttttt atcaacatca ctttattcgt attttcctct
     2461 accataaaag cttcacgctc cacaaaattg ttttatacac tactattcag cccattcaac
     2521 gaccaatgaa tt
//
LOCUS       DADLIO010000148         2461 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.158, whole genome shotgun sequence.
ACCESSION   DADLIO010000148 DADLIO010000000
VERSION     DADLIO010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2461
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.158"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            <1..189
                     /locus_tag="JOX41_002848"
     CDS             <1..189
                     /locus_tag="JOX41_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAY6450525.1"
                     /translation="NSNGILRRNGLPKSIDFREVNQTFISSVSNQRNHIPRKSLNYRT
                     PIEIFLSYVQEAFYSSLI"
     gene            complement(1055..1585)
                     /locus_tag="JOX41_002849"
     CDS             complement(1055..1585)
                     /locus_tag="JOX41_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transferase"
                     /protein_id="HAY6450526.1"
                     /translation="MRLGLIIKNILNLPKTIYFNYKFLHISDAWRLPILVHRKVRITR
                     KSRGKIEIVLQSGKIVYLGFPVLNTAGNEETIISIEGILRIQGPAFIAQGAHIDIRKN
                     AVLDIGSKFNSTGKMSIICFKEIQFKDGCTVSWDTLFMDTDSHTIFELNTHRILNKNN
                     KIVIGKHCWIGAKSVI"
     gene            complement(1582..2199)
                     /locus_tag="JOX41_002850"
     CDS             complement(1582..2199)
                     /locus_tag="JOX41_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAY6450527.1"
                     /translation="MIIVIAEIITDILYKLYEPFGFAVLLTILGLVYFMYATDGIAAG
                     EGYKRILMELYLHLKKDRKYRKVCALIFYTAMILFTTLINRTIWLNPLSDVMGDWWIY
                     KYNTTTGTKELSTACLENIILFIPYVYMVMSIKYENIKKPKIWSSIVYGGKIAFYFSA
                     IIEFLQLFLRLGTFQISDFVYNTLGGILGVILYKLILITKRDGER"
BASE COUNT          810 a          469 c          274 g          908 t
ORIGIN      
        1 aattctaacg ggattctgcg tcgtaatgga ctgccgaaat caatagattt tagagaagtg
       61 aatcagacat ttatttccag tgtcagcaat caacgcaatc atattccaag aaaatcattg
      121 aattacagaa caccaatcga aatatttttg agctatgtac aagaagcatt ttattctagc
      181 ttaatttgac aaatcatata atttaaaatt aacattgatt ctcctatgaa aatatctttt
      241 acctttctcc tgtgaaaagg aaatttcctt ttttatagtg ttattgatat aatcagaata
      301 ttcatcaaac tctgtatctg gagttaaaaa tctacagtaa catctataag ctttgctagt
      361 aatcttcttg ggttctctct ccattgtcaa gcaacatcaa aacacctact tactattcga
      421 ttcttttctg ccaaaaacga gtcagcatca ctcacaactt atgtgttgct gactccgact
      481 agtcctttgt tcaatatcaa cttattaaac agatataata tttttcttta tttcgtatac
      541 tccaagactt ccatctttct ttcatcttat ctctgaaaaa aacacagcaa agtgccctta
      601 ataaatatac attagaattt gcaaattttt tcatcttaag atatatccta ttcatattct
      661 ttacaatcct aatgggtgat tacaaatcta tttagttcaa gttctacatt ataaacacct
      721 ttcttgatag tatcatctgc tgcacaagcg atgtcgatcc acttattagg ggatttacgt
      781 gctcaaaagt ggctattcct tttgggaagt ccatccataa taatggtcca tggatttttt
      841 tagggtcttg tcgttcaaat ttctcaaaaa ctttattata cttccatagt tttataatta
      901 tttggtttca ctttggctcg ttcaaacacc aacttgtatt tcttttcaac gttcgaactg
      961 gagccccccc tataatctca ttattatttt catgactttt tactaccgtg gaattacaag
     1021 caacaacaat attatctgct aaatgaacac ctttctatat cacgcttttt gctccaatcc
     1081 aacaatgttt acctataact attttattat ttttattcaa aatcctatga gtattcaatt
     1141 caaaaatcgt atgtgaatcg gtatccataa ataatgtatc ccacgatact gtacagccat
     1201 ctttgaattg aatttcctta aagcaaatta tactcatttt tcctgtcgaa ttaaactttg
     1261 acccaatatc taaaactgca tttttcctta tgtcaatatg agccccttgt gcgataaacg
     1321 ctggcccttg tattcttagt attccttcaa tacttataat cgtttcttca tttcccgcag
     1381 tatttaatac tggaaagccc aaataaacta tttttccaga ttgtaatact atctcaattt
     1441 tccctctcga tttgcgtgta atccgtactt tacgatgcac caaaataggt aatctccacg
     1501 catctgaaat atgaagaaat ttataattga agtatatcgt tttaggtaaa tttaatatat
     1561 tctttattat caatccgagt ctcatctttc accatctctt tttgtaatca aaattagttt
     1621 ataaaggatt acacccaata taccgcccaa cgtattatat acaaaatccg aaatttgaaa
     1681 cgttcctagc ctcaaaaaaa gttgtaaaaa ttcaattatt gctgaaaaat aaaatgcaat
     1741 ttttcctcca tatactattg aggaccatat tttgggtttc tttatatttt catatttaat
     1801 agacattacc atataaacat atggaataaa aagaataata ttttctaaac acgctgtaga
     1861 taactctttt gttccagttg ttgtattata cttataaatc caccagtctc ccataacatc
     1921 agataaagga tttaaccaaa ttgttcgatt gattaatgtt gtaaataaaa tcatcgcagt
     1981 atagaatatc aaagcacaaa cttttctata ttttctatcc ttctttaaat gaagataaag
     2041 ttccattagt atacgtttat agccctcacc tgcagcaatg ccatctgttg catacataaa
     2101 atagaccagt cctaaaattg tcaataaaac agcaaaccca aagggttcat ataatttata
     2161 taatatatct gtaataattt ctgcaatcac tattatcata attatttctc caatatcaag
     2221 tatacactta tcgcttccaa ttacacatga tcatattaga gtgtattatc acattctcta
     2281 atattcaatt tatttttcct aaaatattcg aaataatcgt cttgataacg agtaagtatt
     2341 tttatacgat tgataacata gtaacaatat ttttaattat agtaaaaaat catctgcctt
     2401 tttcatccac ctaatcttat ttttcatttt attcaacatc cttaaataaa cttccgttcc
     2461 t
//
LOCUS       DADLIO010000149         2459 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.159, whole genome shotgun sequence.
ACCESSION   DADLIO010000149 DADLIO010000000
VERSION     DADLIO010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2459
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.159"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            5..1149
                     /locus_tag="JOX41_002851"
                     /pseudo
     CDS             5..1149
                     /locus_tag="JOX41_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
     gene            1320..1778
                     /locus_tag="JOX41_002852"
     CDS             1320..1778
                     /locus_tag="JOX41_002852"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HAY6450528.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            1937..2407
                     /locus_tag="JOX41_002853"
     CDS             1937..2407
                     /locus_tag="JOX41_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HAY6450529.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
BASE COUNT          823 a          460 c          459 g          717 t
ORIGIN      
        1 aaacatgcac attcaaacaa aattgatcca cggaggcatc agtgaagatc ccacaacagg
       61 agctgtcagt gtacctattt atcaaacatc cacttatcgg caagatggcg tcggccagcc
      121 taaacaatat gaatattcaa gatctggtaa tcctactcgt tttgcattgg aagaactgat
      181 tgctgatttg gaaggcggtg ttcgaggatt cgctttttct tctggtcttt ctgggattca
      241 tgccgttttt tctctttttc aagctggcga tcatatctta ttaggagatg atgtctatgg
      301 aggaacattc cgtctatttg acaaagttct tactaaaaat ggtctcgagt acacgatcat
      361 agatacgagt aatcttgata aaatagaaca atccatcaaa cccaatacaa aagcacttta
      421 tcttgaaaca cctagcaatc cgcttctaaa gattactgat ttagaaaaaa gtgccactct
      481 ggctcatcaa catggattga tagttattgc tgacaataca tttgctactc cttattttca
      541 aagaccttta gatctcggtt ctgatatcgt tgtccatagc ggtaccaaat atctaggcgg
      601 acacagcgat gtagtagctg gtttagtgac ttctaaccaa aagatctagc cgatcagatc
      661 ggattttacc aaaatgctat cggagccgta cttggtcccc aagatagctg gttacttcag
      721 cgcggaatca agacactaag tgttcgtatg gaggaacatc aaaaaaatgc ttttgtggta
      781 gctgattttc tattttctca tccagcagta gaaaaggtct actatccagg attacccgat
      841 catgaactcc atggagttgc taagcagcag atgagcggct ttagcggaat gatttctttt
      901 actttaaaaa atgaagaatc tgctattcca tttgttgaat cactccaact atttacttta
      961 gcagaaagtt taggtggcgt agaaagttta gtggaaattc cttctgtcat gactcatgcg
     1021 tctattccaa aagaaaaacg agaagaggct ggcataaagg acggcttgat ccgtctttct
     1081 gtaggaattg agtatggtca ggatctcata aacgatttag ctcaggcatt tgacagaatc
     1141 aagaactaga agtcccaata aacgacttag cagaaaaatc taaaaaatat ttcagattgc
     1201 tacaccttgg aaacgataag tgttagaatc aagtagaaag acgtttttgt aaatttcact
     1261 aaataattct ttagtgaaaa gcatcaaaac gaatgaacaa acagatagga gtcttacaaa
     1321 tgagaatgaa tgtcgaaagt tttaatcttg accatacaaa agtcaaagca ccttatgtac
     1381 gtgtagctga tcgaaaaacg ggtgcgcatg gcgatgtcat cattaaatac gacgtccgct
     1441 ttaaacaacc aaataaagaa cacatggaca tgccaagtct acattcactt gagcacttga
     1501 ctgccgaact aatccgcaat cacgcagatt acatcgtaga ctggtctcca atgggatgcc
     1561 aaacaggctt ttacttgact gtattgaatc atgaaagcta cgaagacatt ttagatgttc
     1621 ttgaagcaac aatgaaagat gttcttgaag ctactgaagt acctgcaagc aatgaaacac
     1681 aatgtggctg ggctgccagc catacactag aaggtgcaca agctttggct cgtgaatttt
     1741 tagcaaaacg cgatgaatgg tctgaagtag aagcatagtt tctaaaagaa cgtaaagatg
     1801 agaagcaata tagctatctt atcttcgtat tttattaaat atttattgtc tgaaaagagt
     1861 tctaaacggg aaaacaaata gctagttttc agtttagcgc tctttttatt atataaaata
     1921 gaaaggagaa aactttatgt ctatttataa ttttgaaact actttagaag acggcactgt
     1981 ctattcattg aaaaaatatg caggcaaacc gataatcatt gttaacactg caacaaaatg
     2041 cggtctagca cctcaattta aacaattaga agaactttac caagcttatc agacacaagg
     2101 tctggttatc ttaggctttc cttccaatca atttaaacaa gagctagatt cagcgactga
     2161 agcagcagaa gcttgtaaaa ccacttatgg cgttaccttc cctatgcatc aattgattga
     2221 cgtaaatgga gaaaatacag atcctctttt tacttatctt aaaaatgaag ctcctggtac
     2281 tgtcactaaa gcaataaaat ggaattttac taaatttttg attgatagaa atggcaaagt
     2341 aatcgaacga tttgcaccac aaacttctcc attgaaaatg accgctgcaa ttgaatccgt
     2401 tctttaactt aataaaaata aaaaaagatg aactatttct agttcatctt tttgccttt
//
LOCUS       DADLIO010000150         2398 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.160, whole genome shotgun sequence.
ACCESSION   DADLIO010000150 DADLIO010000000
VERSION     DADLIO010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.160"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            207..2069
                     /locus_tag="JOX41_002854"
     CDS             207..2069
                     /locus_tag="JOX41_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAY6450530.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2398
                     /locus_tag="JOX41_002855"
     CDS             2069..>2398
                     /locus_tag="JOX41_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAY6450531.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          865 a          353 c          466 g          714 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataat
//
LOCUS       DADLIO010000151         2277 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.161, whole genome shotgun sequence.
ACCESSION   DADLIO010000151 DADLIO010000000
VERSION     DADLIO010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2277
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.161"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            24..1556
                     /locus_tag="JOX41_002856"
     CDS             24..1556
                     /locus_tag="JOX41_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAY6450532.1"
                     /translation="MIINRKQNAKRNIITGTIFKLYQIIIPFFMRTLMIYQMGMEYAG
                     LNNLFTSIFQMLNLAELGIGAALTVSMYKPIAEDNRKEICALLNAYKKYFSIIGWIVF
                     TLGLLCIPFLRFLVKGSIPGNLNMTVLYLMYLINTVLSYWLFSYRKSLIYAHQRNDVI
                     NVSMLITFTFQFVMQAYVLIFLKNYYLYLLASILGQIVLNLMCAVVSQKMYPDYTPVG
                     ELEKETIDDIIKKVKGLVTNKVGGTILRSSDSIIISSFLGLSVLAIYQNYYFIISAIM
                     SIFAIIYESCIAGIGNSLIVESQEKNYIDFCDITTIIGWFLAISCACFITLFQPFMII
                     WVGSDNLMSISFVIFMIVHFFLYEIDQLIGLYKDAAGIWYADRFRPLITAMINIVLNI
                     ILVNWFGLYGVLAATIVSVLLVDLPWLLYNVFQNIFKFESAGKYVWKLISLCVIAFVA
                     SYLSYFACSYVNIGNFKVISLVINLVISVVISILVILLFNIRNKKFKYILKVLTSVLV
                     KR"
     gene            1734..1955
                     /locus_tag="JOX41_002857"
     CDS             1734..1955
                     /locus_tag="JOX41_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transferase"
                     /protein_id="HAY6450533.1"
                     /translation="MGSSERIKIGNNVFIGMKSRILKGVHIGNNVVIGANSLVNKDVS
                     DDCVVAGNLAKVIMSLDEYYKKINNMKNP"
BASE COUNT          767 a          239 c          435 g          836 t
ORIGIN      
        1 tagaaagttt ggagccatat gatatgataa ttaatcgtaa acaaaatgct aaaaggaata
       61 taattactgg aacaattttt aagttatatc agattatcat tccctttttt atgcgtacac
      121 ttatgattta tcagatggga atggagtatg ctggattgaa caacctgttc acatctatat
      181 ttcaaatgtt aaatttagcg gaattgggaa taggtgctgc actaactgta agtatgtata
      241 aacctatagc agaagacaat agaaaagaga tttgtgcttt actgaacgca tataaaaagt
      301 acttttcaat tattggatgg atagtgttta cattaggatt gttatgcatt ccttttttga
      361 gatttttagt taaaggttcg attcctggaa atttaaatat gacagttttg tatttaatgt
      421 atttgataaa tactgttttg tcgtattggt tattttcata tagaaagagt ctaatatatg
      481 cacatcaaag aaatgatgta attaacgtgt ctatgctaat tacttttaca ttccaatttg
      541 taatgcaggc atatgttctg attttcttaa aaaattacta tttgtattta ttggcttcta
      601 ttttgggaca aatagttctt aacttaatgt gtgctgttgt ttctcaaaag atgtatcctg
      661 attatactcc tgttggtgag ttagagaaag aaactattga cgatattata aaaaaagtaa
      721 aaggattagt tacaaacaag gtaggcggta caatattacg atcttcagat tcaattatta
      781 tttcatcttt cttaggtctt tcagtacttg cgatttatca gaattattac tttattattt
      841 ctgccataat gagtatattt gcaataattt atgaatcatg tatagcaggt ataggtaaca
      901 gtcttattgt agaaagtcaa gaaaaaaatt atatagattt ttgtgatatt acaacaatta
      961 taggttggtt tctggcaatt agttgtgcat gctttattac attatttcag ccgttcatga
     1021 ttatctgggt gggaagtgat aatcttatga gtatttcatt tgttatattt atgatagttc
     1081 attttttctt atatgaaatt gatcagttaa ttgggttata caaagatgct gctggaatat
     1141 ggtacgcaga caggtttaga ccattaatta cagcaatgat aaacattgta ttaaatatca
     1201 tcctcgttaa ttggttcgga ttatatggag ttttggcggc aaccattgtt tcagtattgt
     1261 tggttgattt accctggtta ttatataatg ttttccaaaa tatatttaaa tttgaatcgg
     1321 caggtaaata tgtttggaag ctcataagtt tgtgtgtaat agcttttgtt gcttcttatt
     1381 taagttattt tgcttgttcg tatgttaata tcggaaattt caaagtgata agtttagtga
     1441 taaatttagt tatatcggtt gtcatatcga ttttagttat tcttctgttt aatatccgta
     1501 ataagaagtt taagtatatt ttgaaagttc ttacgtcggt attggtaaaa agatgagaag
     1561 agacatcaga atgatatata aagtaactac aatttttagg ctgccgaata ggcgaacgat
     1621 gtatagtttt tgttccaacg aagactcttg ttgaaattgg agatgatatg aaggagttac
     1681 aattttgact catgtttatg attgatcggt tttaaaagta gtatggagaa gctttgggat
     1741 catcggagag gatcaaaata ggtaataatg tttttatagg aatgaagtct agaatactaa
     1801 agggtgtaca tataggaaat aatgtagtta taggtgcaaa tagtttagta aacaaggacg
     1861 tatcagacga ttgtgttgtt gcaggaaatc tagcaaaagt aattatgtcc ctagatgaat
     1921 attataaaaa gataaacaat atgaagaatc cgtaaaactt gtgaaactat accgagaata
     1981 atatgggaaa aatattgatg aaaaagcatt atatgagttt ttagggctgt ttacagatgg
     2041 agatgacaat ttgtcgaaga gttgggagca atgcaaaatt tagtagggga ttataaacag
     2101 actgacaagg tatttaaaga acatgcacaa gtatttcata atattgaaga atttttgaat
     2161 actgtgagat aggagttgct acattgagaa aagtatgtat ttttccaatg taaaagatta
     2221 cgagtttgaa aacgacacca taatattatt ttttaagaag atattataga gcttagg
//
LOCUS       DADLIO010000152         2218 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.162, whole genome shotgun sequence.
ACCESSION   DADLIO010000152 DADLIO010000000
VERSION     DADLIO010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2218)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2218)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2218
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.162"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(51..1598)
                     /locus_tag="JOX41_002858"
     CDS             complement(51..1598)
                     /locus_tag="JOX41_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HAY6450534.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="JOX41_002859"
     CDS             complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="JOX41_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HAY6450535.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
BASE COUNT          622 a          464 c          397 g          735 t
ORIGIN      
        1 tacgtcaaat aacccgacct atagaataga atcgggaatg tttggcgttt ttagttacga
       61 gaaaaatgtt gttgtacatc cttgttccaa ggcaacagtt gatctaaagt ttctgctgaa
      121 agtacgggaa gatttggtat cttatcaaat agaaactcta gatactttac aggattcaat
      181 ccgttaagtt ctgctgtttt atatacactc agaatgattc ctgaagttcg tgctccttca
      241 agacttgtgg aatgcaacca atttttccgt cctatcacca gctctttgat atttcgctcc
      301 gcacgattat ttgtgagttc taaacgacca tcttcaaaaa taggttcaaa accacttcgt
      361 agtttacacg catattgaac ggctgcatcc aacttggatt ttgcaacagg atctatcgtt
      421 gccatccact cataaaaagc aataaataat ggacgcagtt cttgttgccg acagcttaat
      481 cgcttctcag gagaaaagtc tttccatttc ttttctagga caaaccattt atccaattgt
      541 ttgactgctt gagctgcggg aatatccgtg tttttctttc cttttggaat tgcttcgaaa
      601 aatttccgcc gaacatgcgc gaaacaatag acaagtcgta cactttccac ggcattatac
      661 ccgctatagc cgtcacagtg taaataccct gtaaactcct tgagaaaagt tttcggaaca
      721 tctccagcac gactttcgtc gtggtgataa taaacgatgg gatgctgact gtcttttcct
      781 gtacaaaact gccagtaata ggtatctgtt ttggcacttt caatcacacg ataacttgtt
      841 tcatccccgt gtagaatctc ttcttgatta agatagactc ttaatcgttc tcctaaaggg
      901 tctaacgcgt tttgcactgc tttaatatgc caattggtga tattatctct cgaaatatcc
      961 aacccatgtg tttgtttcca atagttctct tgccgatagg caggaacttt ctgaccaaat
     1021 ttcatccgga tcgtttccgc cactaaacta ttggaaccta agctattaga aatcaaaggt
     1081 ttaggaacga tcgctttttt aaaagaagaa agtccttctt tttcgcagct tttacaacaa
     1141 taggtatgtt gataatgggt gagacaatcc aacatagcct gatggaaacg aatttcttct
     1201 cgtacttttg tccgtccgat atctttcatc tgtgaaccgc aatgttcaca aaattgttct
     1261 tccaaaggaa ggagatgttc tttctctgtt ataggtaagt gtttgatttt gtctgctttc
     1321 gttcctacaa ctcgttgatg tccttttact ggaataatgg tggcagctgc ttctggaaca
     1381 cttacagaaa tttcttcatc actaaaaaga ttcaattgcc cattcgtttc ctcaaagaga
     1441 gtctctttag agcgtccaaa taatttgttg gttaaataat tgaccttttc attcaatagt
     1501 tggatttcag ttgtaagatt ctgaatggtt tgttgttgtg cttgattggt tttatgggct
     1561 tcttgaagca actgaagcaa cgtatctgta gtttccaaaa tttttcacca ccttgaatcg
     1621 aactgatttt gttacagaat accacaagaa acgcacaaga aataggggtt caacacattt
     1681 tttgtgttaa ccccccagct taaaaaactc ctttttttcc tggcaaaata gctcgaggtt
     1741 gatcgatact taatccttct aacaaccatc gaacctgttg gttcgttaag gttcgaactt
     1801 cgtctttcgt ccgaggccat tttaacttgc cgttttctat ccgcttataa cagagaagaa
     1861 aaccatcacc gtcccaatag agaagtttga aacggtcttg acggttcccg caaaataaaa
     1921 aaacggcatc ttcgtaaagc tcgagttgat actcttgttg aataagactg gcaagaccat
     1981 caattccttt tcgcaaatct gtttttccgc acacaatata aatatgtttg gtttgaagta
     2041 aatcataaag cattggacaa cagttctttc aaaatagctt gaagaatata attgttaata
     2101 ccgttataga tcaaaacttc agaaccattc tctcttttga tgcgcatcgc taacttggca
     2161 gccgcgggtt tacctttttc tggtgcactc ttttcgtttc ctaattggac aggaacaa
//
LOCUS       DADLIO010000153         2204 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.163, whole genome shotgun sequence.
ACCESSION   DADLIO010000153 DADLIO010000000
VERSION     DADLIO010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2204
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.163"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(<1..912)
                     /locus_tag="JOX41_002860"
     CDS             complement(<1..912)
                     /locus_tag="JOX41_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HAY6450536.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIY"
     gene            1340..1903
                     /gene="efp"
                     /locus_tag="JOX41_002861"
     CDS             1340..1903
                     /gene="efp"
                     /locus_tag="JOX41_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HAY6450537.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
BASE COUNT          746 a          384 c          421 g          653 t
ORIGIN      
        1 gtaaatgttt tttgataaat agcggtctgc tgcgtctgga aaaatcgtaa cgacacgatg
       61 accaggtggt aaacgacgaa tttctcttaa tgctgctgca aaagccgcac cactcgaact
      121 tccaactaat agtccttgtt ctcgtgctaa ctgcctagta tagttaaacc cttctacatc
      181 agagattgtc tcgatctgat tgattgaaag gggagaaaga aacggcggaa tgaattctac
      241 accgataccc tcaatttcgt gaggggctgg atcaccacca tttaacacag agccctctgg
      301 ttctacaccg attattcgaa tgtcgggata tttttctttc aaaaaggtag aagttccagc
      361 aaaggttcca ccactcccaa ttcctgctac aaaactatgg atattttctt tgatttcatg
      421 aaagatttct ggccctaacg tatgatagta agcagcagga ttatctttat tttcaaattg
      481 aagaggcaga tagctgtttg atatctcctc tgcaagtttt ttacttttgc tgatggcacc
      541 gatgattcct tgctcactag gagaatggat gatctttgct cccaatgctt tcatcaattg
      601 ttgtttttct aagctaaact tctctggaac aacaaaaacc gttcttaatt tgtatgtgag
      661 tgcggccaga gcgatcccaa ttcctgtatt tccggcagtt ggttcgatga tcgtcgtttt
      721 ttcattgatt tttccttggg caaatccttc tttgatcaaa taactgccca atctatcttt
      781 gatacttcct ccaggattta aatattctag ttttgcataa atagcagaac ctttaggcat
      841 agaatagtgc tgattgtcaa agcgataaag cggtgtggaa ccaatagctt ctgtaattgt
      901 cgagataatc atgtgggcct cctaaaaaaa gataataaaa aaaggagctg actattaaat
      961 cagctccttg aaagacatag agaaaaattg agtagataaa aagataagtt acctggtact
     1021 cattctatga agggcaatta atagacatga caaatagtat gctgctttta tgcaccatac
     1081 aacagcaacg attcaattgt ttttggttgc tgactgtcat gtgtatccct ccaagtaaaa
     1141 tttttattaa cgatagcatg aaaaaaaata aaagtcaaag gcttgaaaga aaaaaatatt
     1201 tcgatagcat cgtttacccg tgtttatttt tctgacaaat aggcatgaga ccttaaaaga
     1261 tagagaatac tctagttttc tggccggttg tctgatacaa taaagttgat tatgataaag
     1321 aaaagaagga gcaaaaataa tgatctcagc aagtgattta agagccggta tgactttcgt
     1381 acaagacggc aaactgatta aagttctgga tgcaagccac cataaacctg gtaaaggaaa
     1441 tacagttatg cgtatgaaac tgaaagatgt ccgttcaggt gcaacatacg acacaacgtt
     1501 cagaccagaa gaaaaatttg aaaaagcaca tatcgacaca aaacctgtac aatatttgta
     1561 cacgatggat gatacagctt tcttcatgga tttggaaaca tatgagcaat atgaaattcc
     1621 tgtagaaaca gtagaagaag aaatgaaata tatcctagaa aacatggaag taaaaatcca
     1681 atttttcggt agcgaagtca tcggcgttca attaccaaca actgtcgtat tacgtgttgt
     1741 ggaaacacaa ccttccatca aaggtgcaac agtcactggt tcaggtaagc cagcgacaat
     1801 ggaaactggc ttagtagtca atgttcctga cttcatcgaa acagatgaat tgttggaaat
     1861 caatacagca gaaggttctt atgtaaaacg tgcgtcaaaa taattcgcta acggattgat
     1921 aagaatttga aaacagagct tgacctcttg aaaggcagat catcggatct gcctttcaag
     1981 aggttttttg tggaatcagc aaattgaaaa ataaaaaagt atttgatttt atttatattt
     2041 tgaaagatga atggcaaaag ctagagaaag aaaaaactgc acttatttat gaagaaattg
     2101 aaatgattca taaaattgaa aatatccgaa ctattccgaa ctatattgaa gcgaaaatat
     2161 tttttcatca ctaaatagtg ttgaatttat gtttttatgt ataa
//
LOCUS       DADLIO010000154         2163 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.164, whole genome shotgun sequence.
ACCESSION   DADLIO010000154 DADLIO010000000
VERSION     DADLIO010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2163)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2163)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2163
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.164"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            <1..156
                     /locus_tag="JOX41_002862"
     CDS             <1..156
                     /locus_tag="JOX41_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HAY6450538.1"
                     /translation="GTYGHTGVIRGLANGRMQTYEQNTELGMICGKLDRQYYSASAIS
                     SIVIPPK"
     gene            169..1077
                     /locus_tag="JOX41_002863"
     CDS             169..1077
                     /locus_tag="JOX41_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HAY6450539.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKINYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FERWRQEQEHSFQDWREGQESDYLAWFESIKDILKTIDPGGVMLAELTDARVDIQGVR
                     HASISERLLADMDYLYQKLRATLFTIEYGEIEVTDILQDDLFSDNHEVEKVGTVAFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            1077..1697
                     /locus_tag="JOX41_002864"
     CDS             1077..1697
                     /locus_tag="JOX41_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450540.1"
                     /translation="MAKTKRMMETDEKTGVQRQFFPITHASAVLGLEEIIAGEATVLS
                     VNGKIGAVVITKEDLGLENVLTELPYASEEDDGIITAEMYQKILNSGEGDYVLPVATI
                     DRLGGIKVGELLTIDETGKVSAVRQSDVNFSLELKEKLDSLKNYTAGENITIDEDGTI
                     SSTGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            1701..2150
                     /locus_tag="JOX41_002865"
     CDS             1701..2150
                     /locus_tag="JOX41_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450541.1"
                     /translation="MTDIVKIKQSNVQVYPQTHWNAIEGKPTTVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKAKLDGLANITFEKVGTV"
BASE COUNT          761 a          331 c          494 g          577 t
ORIGIN      
        1 ggaacttatg gacatactgg cgttatccga ggcttagcta atggtcgtat gcaaacttat
       61 gaacaaaaca cagagttagg tatgatttgt ggaaagttag atcgccagta ttatagtgca
      121 agtgcaattt cttccattgt cataccacca aaatagggag gtgatttaat ggcaaagtgg
      181 aatgtcatat taagtacaac agaaccctat aattacgtgg ggatgattca agttcgacaa
      241 ggcaataaga atacagaggt tatggaagcg actatagttg aaaatggtct tccctacgat
      301 ttatcagaat gtaaggtata ttttgaatca gttgtaggtg ggaaatatcc agtccaatta
      361 gaaacaaaaa ttgtggatgc taaaaaaggg aaaattaact atatttttga taaatattcc
      421 atgcagtgtt tacatcgaca aacagccaat ttcattatat ttaaaggaga agacttgatt
      481 ggaacaactc aagacttctc ttattttgtc attaatgctg tttcaaaaac agaaggagaa
      541 atgggttctt attggcaatc aatcgaagat ttaattgcgg atatgacgga ctttattaat
      601 gaaaataaag gcgattttac ggactggatg aatgaaagga aagaagaatt tgaacgttgg
      661 agacaagaac aggaacacag tttccaagat tggagagaag gacaagaatc agactatttg
      721 gcatggtttg aatcaatcaa ggatatttta aagacgattg atccaggtgg agtcatgtta
      781 gccgaactaa cggatgcgcg agtagatatt caaggagttc gtcatgcgtc tatttcagag
      841 cgtttgctgg cagatatgga ctatttatat cagaaattgc gagcaacgct tttcacgatt
      901 gaatacgggg agattgaagt gactgatatt ttgcaggatg atctcttttc agataatcat
      961 gaagtcgaaa aagttggaac tgtagcattc ccgattgaag aaggagcctt gatcatcgca
     1021 accgttgatg atccaaagca aaatgtgttc actcttgaga aagttggggt gatctaatgg
     1081 ctaaaactaa acgaatgatg gaaacggatg aaaaaacggg tgtacaacgc caattctttc
     1141 caatcacaca tgcttccgca gttcttgggt tagaagaaat aatagcagga gaagcaacag
     1201 ttttatctgt taatggaaaa attggagccg tcgtcattac taaagaagat ttgggattag
     1261 agaatgttct cacagaatta ccctatgcaa gtgaagaaga tgacggcatt atcacggcag
     1321 aaatgtatca aaaaatttta aacagtggag aaggtgacta cgtgttgcca gttgccacta
     1381 tcgaccgttt gggtggcata aaagttggtg aattattgac gattgatgag acagggaaag
     1441 tctctgcagt cagacaatct gatgtcaatt tttcgctgga gttaaaagaa aaactcgatt
     1501 cactgaaaaa ttatactgct ggagaaaaca tcactattga tgaagatgga acaattagtt
     1561 ctacaggtgg tagtgggact ggtggtgtca atcagtcata tgtagatcaa aaattccaag
     1621 aagctgtaaa tcaagcagaa aattacacaa acgaaagaat tccaaatttt acttttgaaa
     1681 aaattgggga ggtatagaga atgacagata tcgtaaaaat aaaacaaagc aatgtacagg
     1741 tttatccaca aactcattgg aatgctatag aaggcaaacc aacaacggtg aagggagata
     1801 aaggcgatcc tggccaagca gcaacaatta ccataggaac cgtttctagt ggttcaaccg
     1861 cttctgttac gaatgtagga acatcatctg cagctagatt taattttgtt ttaccaaagg
     1921 gagataaagg tgatcctgga ataaatgcca caactacagc tgtagctaca actacagcaa
     1981 atgggttgat gtcgtccaca gataaaacta agttggatgg aattgcagct ggagcacaga
     2041 aaaatccagg taatgctaca actacgacag caggtttaat gtcagcaact gacaaagcta
     2101 aactcgatgg attagccaat attacatttg agaaagtggg gacggtttaa tggctgatat
     2161 tgt
//
LOCUS       DADLIO010000155         2160 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.165, whole genome shotgun sequence.
ACCESSION   DADLIO010000155 DADLIO010000000
VERSION     DADLIO010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2160
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.165"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            <1..156
                     /locus_tag="JOX41_002866"
     CDS             <1..156
                     /locus_tag="JOX41_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HAY6450542.1"
                     /translation="GTYGHTGVIRGLANGRMQTYEQNTELGMICGKLDRQYYSASAIS
                     SIVIPPK"
     gene            169..1077
                     /locus_tag="JOX41_002867"
     CDS             169..1077
                     /locus_tag="JOX41_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HAY6450543.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETRIVDAKKGKIKYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FDRWREEQENSFQDWREGQESDYLSWFESIKDILKSIDPGGVMLAELMDARVDLQGVR
                     HESISERFLSDLNYLYQKMKAALFTIEYGEIEVTDILQDDLFSDNHEVEKIETVEFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            1077..1694
                     /locus_tag="JOX41_002868"
     CDS             1077..1694
                     /locus_tag="JOX41_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450544.1"
                     /translation="MVKVKRMMETDESGVKRQFMPITHVSAVLGLEKMISGQSKVLSV
                     NGKYGAVILTKADLGLENAITELPYASETSDGILTAEMFQKIVNGEGGTYILPIATPE
                     QLGGIKVGELLEVTEEGVLSATKQTDFNFSEELKGKLESLKILKAGANISIAEDGTIS
                     STGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            1698..2147
                     /locus_tag="JOX41_002869"
     CDS             1698..2147
                     /locus_tag="JOX41_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450545.1"
                     /translation="MTDIVKIKQSGVQVYPQTHWNAIEGKPTTVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKVKLDGLANITFEKVGTV"
BASE COUNT          776 a          308 c          470 g          606 t
ORIGIN      
        1 ggaacttatg gacatactgg cgttatccga ggcttagcta atggtcgtat gcaaacttat
       61 gaacaaaaca cagagttagg tatgatttgt ggaaagttag atcgccagta ttatagtgca
      121 agtgcaattt cttccattgt cataccacca aaatagggag gtgatttaat ggcaaagtgg
      181 aatgtcatat taagtacaac agaaccctat aattacgtgg ggatgattca agttcgacaa
      241 ggcaataaaa acactgaagt tatggaagct acaattgtcg aaaatggtct tccatatgat
      301 ttatcagaat gtaaggtata ttttgaatca gttgttggcg gaaaatatcc agtccaatta
      361 gaaacaagaa ttgtggatgc taaaaaaggg aaaatcaaat atatttttga taaatattcc
      421 atgcagtgtt tgcatcgaca aacagccaat ttcattatat ttaaaggaga agacttgatt
      481 ggaacaactc aagacttctc ctattttgtc atcaatgctg tttcaaaaac agaaggagaa
      541 atgggttctt attggcaatc aattgaagat ttaattgctg atatgacaga ttttattaat
      601 gaaaataaag gcgattttac ggactggatg aatgaaagga aagaagaatt tgatcgctgg
      661 agagaagaac aggagaatag tttccaagat tggagagaag gacaagaatc agattatttg
      721 tcatggtttg aatcaatcaa ggatattttg aagtctatcg atccaggtgg agtaatgtta
      781 gccgaattaa tggatgcacg tgtagatctt caaggtgtac gccatgaatc gatttctgaa
      841 cgtttcctat ccgatctaaa ttatttgtat caaaaaatga aagcagcact tttcacgatt
      901 gaatacggtg aaattgaagt gactgatatt cttcaagacg atctcttttc agataatcac
      961 gaagtcgaaa aaattgaaac agtagaattt ccaattgaag aaggagcttt gattattgca
     1021 actgttgatg atccaaaaca gaatgttttc actcttgaga aagttggggt gatttgatgg
     1081 ttaaagtaaa gagaatgatg gagactgatg aatctggtgt taaacgtcaa tttatgccaa
     1141 ttacacatgt ttctgcagtt ttaggcttag aaaaaatgat atcaggacaa tcaaaagttc
     1201 tttcggttaa tggtaaatat ggtgcagtca ttttaacgaa agctgattta ggattagaga
     1261 atgcaattac tgaactacct tatgcaagcg agacaagcga tggtattctt actgctgaaa
     1321 tgtttcaaaa gatcgtaaat ggagaaggtg gaacatatat tttgccgatt gctactcctg
     1381 aacaattagg aggtataaaa gttggggaac tcttagaagt tactgaagaa ggtgttttat
     1441 ctgcaactaa gcaaacagac ttcaatttct ctgaagaatt aaagggaaaa ttagaatctc
     1501 taaaaatatt aaaagcaggt gcaaatatat caattgcaga agatggaaca attagttcta
     1561 caggtggtag tgggactggt ggtgttaatc agtcatatgt agatcaaaaa ttccaagaag
     1621 ctgtaaatca agcagaaaat tacacaaacg aaagaattcc aaattttact tttgaaaaaa
     1681 tcggggaggt atagaaaatg acagatatcg taaaaataaa acaaagcggt gtacaggttt
     1741 atccacaaac tcattggaat gctatagaag gcaaaccaac aacggtgaag ggagataaag
     1801 gcgatcctgg ccaagcagca acaattacca taggaaccgt ttctagtggt tcaaccgctt
     1861 ctgttacgaa tgtaggaaca tcatctgcag ctagatttaa ttttgtttta ccaaagggag
     1921 ataaaggtga tcctggaata aatgccacaa ctacagctgt agctacaact acagcaaatg
     1981 ggttgatgtc gtccacagat aaaactaagt tggatggaat tgcagctgga gcacagaaaa
     2041 atccaggtaa tgctacaact acgacagcag gtttaatgtc agcaaccgat aaagtgaaac
     2101 ttgatggatt agcgaatatt acatttgaga aagtggggac ggtttaatgg ctgatattgt
//
LOCUS       DADLIO010000156         2019 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.166, whole genome shotgun sequence.
ACCESSION   DADLIO010000156 DADLIO010000000
VERSION     DADLIO010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2019)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2019)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2019
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.166"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            100..570
                     /locus_tag="JOX41_002870"
     CDS             100..570
                     /locus_tag="JOX41_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HAY6450546.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            792..1895
                     /locus_tag="JOX41_002871"
     CDS             792..1895
                     /locus_tag="JOX41_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HAY6450547.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLRDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
BASE COUNT          686 a          328 c          460 g          545 t
ORIGIN      
        1 gaatctctga agaataaatc acgtgatcgt gacgataaaa tacacttacg tcaggtgata
       61 aaaaatacat aagtagaaaa ctaagaggag gaacagaaaa tgaaagaagt tcaattgatc
      121 agaaaaagcg aactatcaga aggtggttgc aatgcatgcg gcgtagtaga agcaacaagc
      181 tatacattaa agcttggtgc caacaaagcg ataatctctg agttgacagt aggcggtctt
      241 gtggacagtc tggcgcttgc tgaaggtttt attggagaag atatttatga gatgttttca
      301 gaaatccgtc agttaaaaaa aggggaaaac tgcatagagg ttcatcatga gagcccgaat
      361 gtgagattca aacgtggtga taatgagatg atcttcaata atcatgtgtc cgatcacacc
      421 gagctatatg gaatcgtgaa tcaaatacta actgagcttt ttggattggg accttatgcg
      481 ttcaaggaag aaaacggtaa tccaaaatta aacgaagaat ggcaagaaac gattgaaata
      541 caaagaaaca acccgcactt atttcaatag gcatccacag tatttcgtaa aagggacttt
      601 gacacgactt ttgtcaaaat cccatcgttt tttatctatt tgtgttctaa acatttcttt
      661 cagagtagta acaactggaa tgactgaaat gtaaacagat tatttgcctg tatcaatacg
      721 gaagagtaat ataaagtgtg taaacgctat catattattc attcaatttt ttatagaggg
      781 aaggcattga aatggaaaaa acgtatcaag caggtacaaa tgaaggaata gtggatttta
      841 tcaatatgga agatttagaa atagccgctt cacaagtgat tccagctggt ggttatggtt
      901 acatcagcag tggtgctggc gacttattta cttatcaaga aaatgaacgg gcattcaatc
      961 atcagctgat tattcctcat gtattaagag atgtagaatt acccgataca actacacatt
     1021 ttgacaaaga aacgctgact gcaccaatca tcatggcacc agttgctgct catggcttag
     1081 ctcatgtgaa ggcggagaaa gcttctgcaa aaggtgtagc agattttggg acgatctata
     1141 cagcaagttc ttacgcttct tgtacattag aagagataag agaagcaggc ggggagaaag
     1201 caccgcaatg gtttcaattt tatatgagca aagatgatgg gatcaatttg gatattcttg
     1261 aagtggccaa gcgtaatgga gcaaaagcaa tcgtattgac agcggatgca acagttggcg
     1321 gaaaccgtga aacagaccgc agaaatgggt ttaccttccc actgccaatg ccgatcgttc
     1381 aggcttatca atcaggagta ggccaaacga tggatgctgt gtacaaatct tccaaacaga
     1441 agcttagtcc aaaagatgta gaatttattg ctgctcattc tgatttgcca gtctatgtga
     1501 aaggtgtcca gtcagaagaa gatgtctatc gttcattaga atctggtgct ggcggaatct
     1561 gggtatctaa tcatggtggc cgtcaactag atggtggtcc agcagcgttt gattcgttgc
     1621 aatatgtggc agaagcagta gataaacgtg taccaatcgt gtttgacagc ggtgtacgac
     1681 gcggacagca tgttttcaaa gcaatcgcat caggtgcaga tcttgttgct attggcagac
     1741 ccgttattta tggattgtct ttaggaggaa gtacaggagt ccatcaagtg tttgatttct
     1801 ttaaaacaga attggaaatg gtcatgcaat tagctggaac acaaacagta gaagatatca
     1861 aaaaaataaa attgcgtgag aatcgtttta tttaagaaac aaatgacgaa aaaaatagga
     1921 gtgcggcaga tgatgccgta ctcctatttt tatagttcaa ggatgtcact aatagaataa
     1981 tttgaaacga aaaaataaaa ttgaaatatt ttttcatac
//
LOCUS       DADLIO010000157         2003 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.167, whole genome shotgun sequence.
ACCESSION   DADLIO010000157 DADLIO010000000
VERSION     DADLIO010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2003
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.167"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            <1..378
                     /locus_tag="JOX41_002872"
     CDS             <1..378
                     /locus_tag="JOX41_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HAY6450548.1"
                     /translation="KNVSTEDFFNYCRLEESGVTVTSGTDLPLFITDIPESIIRAVFR
                     RFPEGEEVWEKETSFTTTELLKSFTSNSFKVNGLSEYGEIKVGKSASLAVFSEDLCTD
                     DWQKVMAAEVIATYLDGDLVYKK"
     gene            426..1826
                     /gene="yfcC"
                     /locus_tag="JOX41_002873"
     CDS             426..1826
                     /gene="yfcC"
                     /locus_tag="JOX41_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HAY6450549.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIV
                     FTMLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIW
                     GIISKGWYMVEISALFLGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGV
                     LVILEGGMIIDTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVM
                     APLGDLMNVSRDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFA
                     ILTLVSAVLLYIATLF"
     gene            1859..>2003
                     /locus_tag="JOX41_002874"
     CDS             1859..>2003
                     /locus_tag="JOX41_002874"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAY6450550.1"
                     /translation="MIKINQLAGMNIHYLFYSLKEFFAYQQKIGISSVELWGGAPHFF
                     IDAF"
BASE COUNT          555 a          339 c          432 g          677 t
ORIGIN      
        1 aaaaatgttt ccacagagga cttctttaat tattgtcgat tagaggaaag tggtgtaaca
       61 gtcactagcg gtacagattt accgctgttt attactgata ttcctgaatc gattataaga
      121 gcagtattcc gtcgttttcc tgaaggagaa gaagtctggg agaaagaaac aagcttcacg
      181 acaaccgagc tgctgaaaag ttttacaagc aacagcttca aagtaaatgg tttatcggag
      241 tacggagaaa taaaagtagg gaaaagcgcc agcttagctg ttttcagcga ggacctctgt
      301 actgatgact ggcaaaaagt gatggctgcg gaagttatcg ctacctatct tgatggtgac
      361 ttagtttaca agaaataatg cttttcgata taacgttata aaacgaatta aagagaggtt
      421 aaaaaatgga aacaatgaaa agaaaattca ccttcccaca tagttataca ttgattttta
      481 tcttaattat tttggctgca attttaactt ggataattcc tagtggtcag tttgagacag
      541 ttgttgaaaa cgtcgcaggt atggaaaaaa caacggttgt tccgggaacc tatcaccaaa
      601 tcgataaggc agattatgga caaggttttt cctctatact aatggcacca gctgaaggga
      661 ttatttcagc tgttgaggtt gttgcttttg ttctcatcgt tggtggtgcc ttcgggatta
      721 tcctaaaaac gggagccatc gatcgagggc tgtttacctt agcaaaagtt ctgggagaca
      781 aggggatctt agttattccg atgtcgatga ttctattcag cttaggagga tcaacctttg
      841 gcatgagcga ggaagtcatt cccttatttg cggtgtttat ttctctgatg ttttctcttg
      901 gctatgattc catgactgcg atcttgattc tatttttaag tacacaagcg ggatatgttg
      961 ggtcgacgat taatcccttc aacgttttaa tcgcacaggg agtagctggc gtttacggaa
     1021 atcccctgct ttggtttcgg atgctatcct ggattgtcat tactgggatt tcaattgttt
     1081 tcaccatgct ttatgctagc agagtcaaaa agaatccact gtcctctatt gtttatgaga
     1141 gtgatttaaa ggttaagcat aagtttcaaa attttgacac tgaaaaagag ttttcaacac
     1201 aagataaact aattatcgcc ggttttatcg taggtttagg aatcatgatt tggggtatca
     1261 tttccaaggg atggtatatg gttgaaattt ctgcactatt cttaggatta ggtctttttg
     1321 ctgggggcat cgctagattt tctcaaaagg aaattgctga agcttttgtc gaaggctgtt
     1381 cagatttcgc ctatgctgct gtaatcattg ggctagctag aggagtcttg gtaatcttgg
     1441 aaggtggaat gattattgac actattctaa acagcttggc taacctttta ggtggtcttc
     1501 caaaattcct gttcactacg attctactca tttctcaagt aattgtttcc ttttttgttc
     1561 catcctcctc aggagctgcg gcattaacga tgccggttat ggcaccattg ggtgatctaa
     1621 tgaatgtaag tcgtgatgtt gttgttctaa gtaaccagtt tggaaatggt ttaatgaata
     1681 ttatctcccc aactagtggt gtattactgg caggattagc catcgcagag attaatttct
     1741 ctaaatggtt taaggttggc ttcaaaatat ttgccatctt aacccttgtt tctgctgttt
     1801 tgttatacat tgctacactc ttttagtctt aatcatccat taataggagg caatagttat
     1861 gattaaaata aatcaattag caggaatgaa tatccactat ttattttatt ctctcaaaga
     1921 atttttcgct tatcaacaga aaattggtat ttcttctgtt gaactttggg gaggtgctcc
     1981 gcattttttc atagatgctt tta
//
LOCUS       DADLIO010000158         1979 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.168, whole genome shotgun sequence.
ACCESSION   DADLIO010000158 DADLIO010000000
VERSION     DADLIO010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1979
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.168"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(325..528)
                     /locus_tag="JOX41_002875"
     CDS             complement(325..528)
                     /locus_tag="JOX41_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450551.1"
                     /translation="MSQLGKRYSLSKSNRKVYTLFISDSVKEGFTLGFSISFKKGTKN
                     TSISHNNRELTDSQKINGLSGRK"
     gene            complement(728..1744)
                     /locus_tag="JOX41_002876"
     CDS             complement(728..1744)
                     /locus_tag="JOX41_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HAY6450552.1"
                     /translation="MANENQLSEIQSKIEGRGAEKRTTINQLEKLNRISNRRLSVQGT
                     TTPLKLNWSIDRITIVGKLNDTIAYWTKNGVVFVDFEQLMRLNENQGYLKSVGINGWQ
                     LFDQYGEDIAYIEILKFHEGKGRIDFNPNKIGQFLASSMKGFIHDLFLDPHFSRADIA
                     CDIVDVPDDFITQYRIVDPISFKPIYGRSGKLETAYWGSRASERQVRLYNKKLEQERK
                     KVIVPKEIDTWWRLEMQLRRGKATDWHAMVQESLDSFASPHFLPIDIKPIDKIVIDGL
                     IAEPSNWSIIARHTKYKYRNLLKQESQNDELTNHLRETFKESADELKKELDTWLLGLD
                     VTEK"
BASE COUNT          556 a          460 c          310 g          653 t
ORIGIN      
        1 aaaaaaataa aaagacctca gggaatttca ttccccgaac cccttgagcc tcctcctgcc
       61 gaaatggaaa gggcgcaccc gctgtttatt tcattcagct atcggttttc acaatctaac
      121 acgatcgttc cgctaccagt cgccttacag gctccatttt cgctcctcta acgtgtttta
      181 acgattgtgc cgataactaa acgaaataaa cgctaaaacc gctcagaacg caaaatatgc
      241 cattttagag ctattgtaga aaatgtagtt tgaaatgcaa ttttcttctt tcagcttttt
      301 atttcccact tgtaaatctg ctaattattt tctaccagac aaaccattga ttttttggct
      361 atcagttaac tcacgattat tatgagaaat gcttgtattc tttgttccct ttttgaacga
      421 aatactaaac cctaaggtga acccctcctt cacgctgtcg ctaataaaaa gagtgtaaac
      481 ctttctgtta ctctttgaca aagagtaacg ttttcctaat tgtgacatgg ctgtcacaat
      541 tccaaacgct ctccgaggga tttcgctgtc acaagtgaca acgaaaaaag gagccgaaag
      601 cgtgtcacgc tctcaactcc ttttacgctt tattttgctt catgcaaaat attcgcttat
      661 cgtgaattta cgtcactaaa cattgacgca aatccactct cactcatctg acttttctta
      721 ttcggtatca cttctctgtc acatccaacc ccaaaagcca cgtatccaat tcttttttta
      781 attcgtctgc agattcctta aaagtctctc gtaaatgatt cgttaactca tcattttgac
      841 tttcttgctt cagcaaattc cgatatttat attttgtatg tctagcaatt atcgaccaat
      901 tagaaggctc agctatcaaa ccatcaataa ctattttatc aataggtttt atatcaatcg
      961 gcaaaaaatg cgggcttgca aaactatcta agctttcctg aaccatcgca tgccaatccg
     1021 ttgctttgcc acgtcttagc tgcatttcta accgccacca cgtatcgatt tcttttggca
     1081 cgattacttt ttttcgttcc tgctctagct ttttgttgta cagtcgcact tggcgctcac
     1141 tggcacgact gccccagtac gctgtttcta gcttgccaga acggccgtag attggcttaa
     1201 aagaaatcgg gtctacaata cgatactgag taataaagtc atccggcaca tctacaatat
     1261 cgcaggcaat atccgcccgg gaaaaatgcg gatctaaaaa taggtcatga atgaatcctt
     1321 tcatggaact agctaaaaac tggcctatct tattcggatt aaaatcaata cgaccttttc
     1381 cttcatgaaa tttaagtatt tcgatatacg caatatcttc tccatattga tcgaataatt
     1441 gccagccgtt tatcccaact gatttcaaat atccctgatt ttcgttcaaa cgcattaatt
     1501 gctcgaaatc gacaaaaaca actccatttt tcgtccaata agctatggta tcattcagtt
     1561 ttccgacaat tgtaattcga tcaatcgacc aatttaattt taggggggtg gtcgtacctt
     1621 gcacacttaa ccgcctgtta gaaatacggt taagtttttc gagctgattt atcgttgttc
     1681 ttttttctgc ccctcgacct tcaatttttg attgaatttc actcaactga ttttcatttg
     1741 ccattttcgt cctccaaacg aaaaaagaga cttttggaaa gaatttccag agttcacgta
     1801 accctaaaaa ttcatatcca aaaatctcta gcttgaagaa acctaaaaat attcgtataa
     1861 tgaacctgag ttacggagct aggtgaagta gtttccgtaa atagtcgaga gtgttagcgc
     1921 actgctcggc ttttattttg ctcttttttc tcgttttctt tgattatagc actcctcct
//
LOCUS       DADLIO010000159         1943 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.169, whole genome shotgun sequence.
ACCESSION   DADLIO010000159 DADLIO010000000
VERSION     DADLIO010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.169"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(<1..349)
                     /locus_tag="JOX41_002877"
     CDS             complement(<1..349)
                     /locus_tag="JOX41_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450553.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIVGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(342..1667)
                     /locus_tag="JOX41_002878"
     CDS             complement(342..1667)
                     /locus_tag="JOX41_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAY6450554.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRS
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTKSLNLFTTEETRSQRRKKLAQMIQERIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFIAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGILSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLNIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQINEEN
                     LDKIIDKIRQKYGFTSIVHASSMLESARSITRSTLVGGHAGGNGGIKND"
BASE COUNT          553 a          402 c          293 g          695 t
ORIGIN      
        1 attctaatcg actccattta ttatcctggt aaaattcgat atgacgtatt tcgtcgtagt
       61 gaattttgtc ttttccaacg tagatcccca gctcatcact acctaagatc ttgccaacaa
      121 tatcttctgg atagtatcct tcagcgtttc gttcttcttt ttgaatagat actgatctat
      181 tttttatgac tgcagcgttc aatacttccg caatctcttc agtcgtcatt tgttcttttg
      241 ctaaattttg actggttcgt tgttcattgt cggcatcaat ttcttcagta tgatcagata
      301 aataaaaccc tgcccacttt aaacgtccac gatcattgta atcaatcatt tttaattccc
      361 ccatttccgc ccgcatgacc accaacaagt gtgcttctag taatgcttct agcgctttct
      421 aacattgaag aagcatgtac aatcgacgta aaaccatatt tttgccgaat cttgtcaata
      481 attttatcta aattttcttc gttaatttgc ttttgtggat cactaaataa atccagctga
      541 agcgaatcgg tgtacacaag cttgctatag gttattccaa cgtgccttac ttcttgtcct
      601 tcataatact tatcaaacaa gaaaagacaa taattctgca attcctttgt attatctgtg
      661 ataggtattt tcatctggtg tgaaaatcct ggtctcgttt ctaagatcga cgtaccaatg
      721 tttaaatgaa cacatcctgt tttacaatta tgctgcctga tacgaatggc tacttgttcc
      781 gccatttctt ttaccaccag ctcgatttca tttcttctag tataatctcg tggtaacact
      841 tgtgaattac cataagattt ttcctttgtc ggttctggcg ggattgctat atctgttcga
      901 tcgattccgt tagcatggaa gtacagctgt aatccaatca cacctaatct attcttaatc
      961 gtataaggat tccagttagc aaggtctcta atgctcaaaa ttcccatttg gttgagcctt
     1021 tttttcattc gagaaccaat tccccaaaag tccgtcattt cgggaatatt ccatactttc
     1081 tcaggaacgt tttcgtacgt ccattccgca ataaatcctt cattatgctt tgcttcattg
     1141 tctaaggcta atttagccaa aaggggatta tcgccgacgc ctaccgtagc aatcaaacct
     1201 aactcttctt taatacgttc ttggatcatt tgagcgagct tcttccttcg ctgacttcgt
     1261 gtttcttcag tcgtaaaaag attcagtgat tttgtcactt ttaaaatcga ttcatcgatc
     1321 gagtaaatca gtagatcttc atcagccaca tatcttctga aaatattatt tacctgcata
     1381 tttcgcttga tatataggtt catacgtggt ggaacaacgt gtagtgtttt aggaaatggt
     1441 tgtggtaagt cacgtggtct actcacattt gtaataccat accgcttttt tgcttcagga
     1501 gaagaagcta atatcaatcc tgaaccagta ttatcagatc gactcataac aacaagttct
     1561 gttgttaatg gatctaaatt tctttctata cattcgacac ttgcgtaaaa gcttttcata
     1621 tcgattaaaa agtaatcatt tactggctct tttgaataat ccatcataaa taacactcca
     1681 ttcttccaca ttatacaaac atatgttcga tgttgtaaag aagaaatagc taaatacata
     1741 aaaaaagaag cataggtatg ctatcaccct gcttcttctt atgatttgta tgatcaattt
     1801 attctatcac tttactaatt aatttgaaaa tctaataaaa actctcactc taaaagagtg
     1861 agagactgca aattagagta cggacttttt tggagttccg ttctttaata ttaacaaatg
     1921 aataaaatcc ttacaacatt tga
//
LOCUS       DADLIO010000160         1820 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.170, whole genome shotgun sequence.
ACCESSION   DADLIO010000160 DADLIO010000000
VERSION     DADLIO010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1820)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1820)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1820
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.170"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(485..1057)
                     /locus_tag="JOX41_002879"
     CDS             complement(485..1057)
                     /locus_tag="JOX41_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAY6450555.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(1073..1678)
                     /locus_tag="JOX41_002880"
     CDS             complement(1073..1678)
                     /locus_tag="JOX41_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HAY6450556.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
BASE COUNT          536 a          367 c          271 g          646 t
ORIGIN      
        1 aaggagactt gaatgccatt attactttaa tcgtagttat ggtaaaatca ataggtaata
       61 tcacaatagg aatgctgttt attatattag cagcagtgct gatttttatg atagttattt
      121 ggttcttaaa tgaaagatct aaagacaatc aacaccgtag ggatatggag ataaaatcaa
      181 tagagtcaat agattattta tcgataataa cactaaaaaa gccacgttcc taaacgtgac
      241 ttacgctgaa cgatatgtgt tgtttggtag acgaacaaat cgttcattat aaatatatga
      301 tggtatccta atatagtaag cgtggctagc atacctttaa ttactttacc ttttacagtt
      361 accatacaca ttttttgagc agaaatcaag taaataaaaa aatattatat ttcacaacat
      421 gctaatagac tcatatctag aacgcattaa gtatttacct gtctggttcg ctgagacttc
      481 ttttttaact ttcttcaatt ttcttcttta ttctaaaaag cgtactgcga ctgaaaccgg
      541 ttatagcttc aacttcctta tacgatttac ctgaagtaag cagttcatat gcgtgcctct
      601 tcttcggtgt gattgttgct ttcggacgtc cttctctgaa attaggatta ttctttcttg
      661 caaacatttt tccttcttgg gtacgttcca caatcatatc acgttccatt tctgctacac
      721 tcaacaacgt ccgtgtcacc attcgcccca tggacgtatt ttcaatcgtt cctagattca
      781 aaaccttgat cgttacgtta tcatcgagta aaggttcaat gatctctaat gcttctctcg
      841 tgttacgagc aaatcgatca agcttcgtaa caactatttc atctccaggc ttcagaccag
      901 ccaacagctg attgaatttt ggccgatccc gttttgtacc cgtaaatttt tctgaaaaaa
      961 tattcttctt ctctacgccg ttctcaagca actgttgaat ttgttctttt gtactttgag
     1021 aagcggttga gacacgtgca tatccatatt tcgtcatttg gtccacctac ttttacaaat
     1081 catctatcgt atactcagaa tacccttcat agaaatagct gacatcgatt cctttcatat
     1141 ataactcgcg atcgtcaatt ttatcagtca gagcattgga aattagatag cgtatttcca
     1201 aatcgtttat gggacttcgc tccattgcag aaagatagtc tgctttatcg attaagttcc
     1261 aatctacaac tttttgcaat tcttccttta aaatgagatc cagccaaatt ctagtacttc
     1321 ggccatttcc ttctcgaaat gggtgagcga tattcatctc cacatatttc ttgataatct
     1381 cttcaaaaga agtttgtggc atctgatcaa tatgctgtaa cgaatgttct aaatacataa
     1441 ctggtgcaaa tcgaaaattt ccttttgcaa tattgaccga tcggattttt ccggcaaaat
     1501 cgtaaatatc cgaaaataga aattcatgaa tttcagataa acctttaaat gtaccaactt
     1561 cgatttcatt tatttttcca caatcgtaca attctttcgc tttttgttta ctgagttttt
     1621 cttcaacctt agccaactca acttgattgg ttaatcccaa tttattctct aaaatcatgc
     1681 gaaatctcct taactttatg acataagttt atgaaacact ctcaacccca ttatatcgcg
     1741 attttgttta tgtgtcaaaa actattaagt ttctgacccc cgatagattt ttcaagtgtc
     1801 tctattttgc acagtctagt
//
LOCUS       DADLIO010000161         1804 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.171, whole genome shotgun sequence.
ACCESSION   DADLIO010000161 DADLIO010000000
VERSION     DADLIO010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1804
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.171"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(<1..251)
                     /locus_tag="JOX41_002881"
     CDS             complement(<1..251)
                     /locus_tag="JOX41_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAY6450557.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKE"
     gene            complement(248..901)
                     /locus_tag="JOX41_002882"
     CDS             complement(248..901)
                     /locus_tag="JOX41_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAY6450558.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            1189..>1804
                     /locus_tag="JOX41_002883"
     CDS             1189..>1804
                     /locus_tag="JOX41_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAY6450559.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQILKVKEKLTILELKRTRFLCYDCGQTFSAKTDLVDE
                     HHQLTKELKQAILIELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMKSVSGSMSFICVDGTTHQLFTILEDRRLYKLTQYFLR"
BASE COUNT          572 a          326 c          241 g          665 t
ORIGIN      
        1 ttttctttta tgaatacttt tatttcacta ctcttggaat aaaactccaa agtttgttct
       61 atatatttta tttcttttcc attcatatta ctagaaattt catttgccat attatgaatc
      121 ttttcttttc tcgtctccaa atatgtttta ggaaagataa aaaaaattaa tgaatgaact
      181 aatataatta ttattccaag aacagaaaat atttgtatga acatttttgg aaatatcttt
      241 aattttttca ttttctctcc aatttatatc ctacatttct tatagtagtt atacagtcta
      301 attgtaattt ttttctaagt tcttttatat atacatctat tactcgatca taaggagttt
      361 cttcgctatc tttccataca taatcaataa tttgcattct tgttaacact tgtccattat
      421 tatccaataa acattttaat acttctagtt cttttgcatt tacatctatt tcttcaccat
      481 ttattttagc tgtatagcta ttaaaattaa ccgatagatc cttatattca aacttctcta
      541 aatgtccata attcttctta attaaagaat ctattctagc ttttaagacc ggcaatgaaa
      601 atggcttttc tacatatccg tctactaaat tagtaaatgc atcaatttta tattcttcat
      661 cactaaatgc agtcaagatt agaattggta aattgctttt ctttctaatt tctttcaaca
      721 cttctaaacc atttataaaa ggtatctgaa tgtctaagat aaccaaattt atatcgctat
      781 taaattttga caaggcttct cttccatctt tagcttgaat aacagtatat ccaaattctg
      841 aaagatattc acttattccc tctcttatca tattatcatc ttcaacagtt aatattttca
      901 tatatacctc cacttaagcc tatacactag atattataca gcatattatg gctctataat
      961 atctagtgtt ggtgacacct tctgttgcca atactttttc ttttttctaa taaatgcaaa
     1021 cagacacctt gaaatccttt agaataaagg gttctataat attttgtgtt gttggaaaat
     1081 cgaaggcgat tttctactaa cactttttct tcgtttcaac tcaaaaagag actcactttt
     1141 ggtaaaattt agtcgaccaa aacatcaccc taccaaagga gtcgctctat ggataatcat
     1201 actagaaaat tactcggatt aacagataaa catttatttt ttgatgaaga atggctgatt
     1261 gaaaaagaat ataaaggcgt tcaagcgcag tttattaaag ggagattgga tgactcacct
     1321 tcccattgtg aacactgtgg atcgattcgt attatccgca acggttccta tacgacacgt
     1381 actcagatat tgaaagtcaa agaaaagttg actattttag aattaaaacg tacccgtttt
     1441 ctatgctatg attgtgggca gaccttttct gcgaaaacgg acttagttga tgaacatcat
     1501 caactaacaa aggaactgaa gcaggcgatt ctcatagaac tgtacgaaaa tcaatcacgt
     1561 aaactaatcg ctaagaagta cttcgtctcg gatgggacgg tgacacggat cttgcgtgaa
     1621 gcaacgaagc attaccagcc acgtatgaac ttccttccga cggtgttgtg tatggatgag
     1681 ttcaaatcaa tgaagtctgt ttctggttcc atgagtttta tttgtgttga tgggacaacc
     1741 catcagctat ttacgatcct tgaagatcgc agactttaca aactaactca atacttcctg
     1801 cgct
//
LOCUS       DADLIO010000162         1728 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.172, whole genome shotgun sequence.
ACCESSION   DADLIO010000162 DADLIO010000000
VERSION     DADLIO010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1728
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.172"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            80..490
                     /locus_tag="JOX41_002884"
     CDS             80..490
                     /locus_tag="JOX41_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAY6450560.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            504..860
                     /locus_tag="JOX41_002885"
     CDS             504..860
                     /locus_tag="JOX41_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HAY6450561.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
     gene            complement(1470..1613)
                     /locus_tag="JOX41_002886"
     CDS             complement(1470..1613)
                     /locus_tag="JOX41_002886"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450562.1"
                     /translation="MEKEAFDLHVLGTPPAFVLSQDQTLIKSSNNLAIVKLNLFASIL
                     LAC"
     gene            1533..>1728
                     /locus_tag="JOX41_002887"
     rRNA            1533..>1728
                     /locus_tag="JOX41_002887"
                     /product="16S ribosomal RNA"
BASE COUNT          620 a          268 c          335 g          505 t
ORIGIN      
        1 ttatatttta ttagctaata attggtattt taaaagaaat tactgtagaa ttggattata
       61 attaaaaagg agtgagaaaa tgataaaagt atatacttcg cctagctgta cttcctgtag
      121 aaaagcaaga gcatggttgc aagcgaatca acttgaattt gaagagaaga atatttttgc
      181 cgaaccgtta acagaaagtg agatcaaaaa gatcttggca gcgactgaag gaggagttca
      241 agatattatt tccactcggt cgaaaattta cgaaaagctg ggcatagatt ttaacgaatt
      301 aactttaaag caaatgatcg tcttattcaa agaatatcct tcattattga gacgacctat
      361 tttgattgat gaaaaaagaa tactaatcgg atttaatgaa gatgagatcc ggtcatttgt
      421 ccctcgtgaa attcgatgtg ttgccagaaa tctgatctat ttacaaaaca ataacatctt
      481 aaattcatag ggagggagcc ttcgtggaag tgaaagtcta tggatcagcg cactgtgtaa
      541 caagtctgaa ggcgaaacaa tggttagaac accatcaatt gccttatcaa tttgttgact
      601 tagaagaacg cgatctaagt acagaagaag cagaagaatt atgcagtttt gaagaagtgc
      661 aagcagaaca gctatttgcg acttggtctg aggcttttca caacattgcg attgaccttt
      721 cctgtgtagg aaaaaaacaa ctgatttttt tatgcacaca acataccaat ctcctcagac
      781 gtcctttgat tattatcgat gaagttctat ttattggata caatgagcag ttgatggaac
      841 agcttatctt aaataaatag actttaactg ttttaatcaa gtcactgagc atttcataca
      901 gttgtaacag tcgaacactt agcatcaagc gtgttatgtg ttcttttttt gactttattt
      961 ttctactata gagacatgct caatttatgt ggtcaaaatt caaatctagg tggggatata
     1021 gagttaaaaa tatattgaca tgtgtaaatt tacatgatat attcatttct gttgttttaa
     1081 gtagcaaagc aataaaatag tattttaaaa aacatataaa atagttgttg acatgttaga
     1141 aatgacatga taagataact gagttgttaa aaaagaacca cttgtgaagc ttgattctat
     1201 cgaaaaaaac ttcaaaaaag ttcttgacaa ataacaaatg ataagttatg ataaatgagt
     1261 tgctgtaaga tttcgaaaaa cgaaatcaaa aaaactttta aaaaagagtt gacaattact
     1321 tgtctctctg atatgatata aaagttgcta cggcagccaa aaacgaatcg gggaacactc
     1381 ctgatgaagt agacctttga aaactgaaca aagtaagaca aaccaaatgt gtagggcgtc
     1441 ttgattcaat tcaagacaac aaacattttt taacaagcaa gcaatatgct agcaaacaaa
     1501 ttgagcttaa caatcgcaag attgttcgaa ctttttatga gagtttgatc ctggctcagg
     1561 acgaacgctg gcggcgtgcc taatacatgc aagtcgaacg cttctttttc caccggagct
     1621 tgctccaccg gaaaaagagg agtggcgaac gggtgagtaa cacgtgggta acctgcccat
     1681 cagaagggga taacacttgg aaacaggtgc taataccgta taacaatc
//
LOCUS       DADLIO010000163         1648 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.173, whole genome shotgun sequence.
ACCESSION   DADLIO010000163 DADLIO010000000
VERSION     DADLIO010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1648)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1648)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1648
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.173"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            6..>1648
                     /locus_tag="JOX41_002888"
     CDS             6..>1648
                     /locus_tag="JOX41_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450563.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQRKTNGQ
                     PMNDKRNGHSWFRQQERLENKVHSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIENIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKERSEKGKENLLPEVQAI
                     IDSGRVTQWKKNPTIYFLKDYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKENDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQTVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQAR"
BASE COUNT          679 a          265 c          361 g          343 t
ORIGIN      
        1 cggacatggc agaagaaaaa gaaccactag acaatagtcg cttgggaaaa tccaaaagaa
       61 aattagtacg attgcaaaat gaattaaacg aacaaattga gaagatgttt gaacaccaga
      121 gaaagaccaa cggtcagcca atgaacgata agagaaatgg gcattcttgg tttaggcaac
      181 aagaacgttt agaaaacaaa gtgcatagtc tgagagaaga gatcaagcaa caagaaaaac
      241 aggtagaaaa acttgaaaga caagaagagc taaaggaaat gggctataac aagtacggcg
      301 gcctggatat gacaatcgaa aatattccaa gaatcaaaga agaaatcgaa cgctttgaaa
      361 aaggtgaatc gactttttca gccgctacga tccgaaaata ccaacggaaa ttggaaacat
      421 tagaacagct gaaagaaaga tcagaaaaag gaaaagaaaa tcttcttcct gaagtacaag
      481 caattattga cagcggacga gtgacgcaat ggaaaaaaaa tccaaccatt tattttttga
      541 aagactatcg aaaagttgct ttagaactga atgaaaacgg gggatttgag gaatcaaaaa
      601 aataccaagc cacgtcggaa gaggaaaaag cagctgttcg tgaattactt gaagaggctg
      661 cgccaactga ttctttgaag gagaaagaaa acgatcattt ctatcgagta gaattcaacg
      721 aaaatgatcc agaaaaagga ttgaaaagtt atggtgggga gatcgtaaca ttagaattga
      781 tcgatcaact caaaacgttg gataaccaat acgccgcaga agcaggttat tataaattct
      841 attttgaaga agtgaagaac ggagaagtag tcgatcagat ccgaatggat ctaggggatg
      901 gcgtcaacag taatcaaccc atctatttag agttagcaaa attgtgcgaa caagtacctg
      961 aaaaggaaca aaaacaaacg gtcaaaaatg aacctgtttc gaaagaacaa atgcagtcga
     1021 aagaaacaaa aacaaaacaa aagggctatc aaaaacgaac ggcagaagag attaagcaag
     1081 aagtcaaatc cctttcgcaa caggcactgg atgcggtgaa aaagcatacc cattctcctg
     1141 aagacgtgaa agaacttttg aattttatgt ctcgttttcc agaacgatcc tttagaaatc
     1201 aattattgat tgaggaacaa tttccaggtg caacggcttg tttaggtcgt gctgcgttga
     1261 aaaaagaagg aatctatatc aaaaaagggg aacaagggaa caagatcttt gtcagaaaaa
     1321 cggtcaaagg attttatgag aaaggacgtg gctttgttcg agaaacagaa gctacaccag
     1381 aagataaaaa acgaatcgaa agtggtcaaa tcgaagtgat caaaaaacct tactacacga
     1441 ttgaaaaagt gtttgatatc acacaaacac agttaaaacc tgaagactat ccgaaaatct
     1501 ttccgaaccg tgtctttgat tttcaattgg ataaaaaagg acagtcagaa cttcaagctg
     1561 ggattcaagc ggtagccaac aatattggaa tacaaattcg agatatgaca gaaagtgaag
     1621 tctatcaaag agaattagga caagcacg
//
LOCUS       DADLIO010000164         1636 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.174, whole genome shotgun sequence.
ACCESSION   DADLIO010000164 DADLIO010000000
VERSION     DADLIO010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1636
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.174"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(183..1502)
                     /locus_tag="JOX41_002889"
     CDS             complement(183..1502)
                     /locus_tag="JOX41_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HAY6450564.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
BASE COUNT          485 a          301 c          325 g          525 t
ORIGIN      
        1 attctttggc acattttatt gaaatatgta tcactaatat ccctatcaac tgattttgac
       61 taaaaagtta cttcaaacat tcactgttca aaaatattga ggaataaatt ttgggtgtaa
      121 ggcattttga gcatacttct ccctggataa cttcccagta aaaaaatcgt tagattgttg
      181 gattagatcc attgactggc tcgcctcagg cgagcaaaga ccctgtagaa ttcattctga
      241 tacacatgat aactagataa tttgagatag actcgtctac ccgtttggac taatttccca
      301 gcaactttca gaaacttcaa tcgaatagaa tgaatggtca ttcccttttg gacttcttca
      361 aagccaatcg ttcttaagaa gttgactaag ttgtaagcta tcaagctgag catcattcgg
      421 acatgattct ccaaaaagcg aggactgtct gttttgtcaa agtaaaagcc agctttcgct
      481 tctttaatga agttctccat tgtgccacgt ttggcataga tagaaaagat ggtatcagga
      541 gaaacatttt ctgatagatt cgtcacgata aattcatgtc gaaagagtag ttcgcccgct
      601 tcacgtgttg agcgtataca cacgcgacga ctttgtgacc aggattgtgc ttgataagtg
      661 gtcgagaagt actgaacttc tcgttcttcc cacttttgat tatcgccata aagtactgat
      721 ttctcagcta tttgacctag tctacgatta ttcttcagtc gaataacata atgactcttt
      781 tttgattcac acgaatcata cacaccaggt gtagcgaacc cgctgtctcc acgaaccaag
      841 atgtcagtgt ttggtagaga gtgattatag tgctctaata aaggtgtgag aaactccttt
      901 acgccttttg atgtatattg atttcctgaa cgtagttcag cttttaagaa gtcaccagtc
      961 aatccgtcaa aagctaccaa tggatggtaa ccataggttt ggtagtgtgt attataattc
     1021 gtttgttctt ggtgaccaaa tgtatctgaa tgggtcgaat ctaaatcaat gattaattcc
     1081 gtatcattac ggatgaggcg tgctttatcg ataagttctt ggttcaaagc ttgaagttca
     1141 tggatattct cctcagatag tcgatctaaa aatcgggaaa gtgaagattg agaagcgagt
     1201 tctttcctat ctaaaacagc tttaaacaca ggatcttgtc tcaggagatt agctgcagaa
     1261 tcagctgagt aaccagcaat taattgcata atgaactgct caagtatgga taagttgtca
     1321 tgagtaaaat acgctcgttc gtcttcaatg tgaatgtgtt gcttagccag ttcagaaaaa
     1381 ccaaagatgt tcatcagctc tttcactagg acgagacccg aatcactcga taattgacca
     1441 cctgtatgag aaatagtgat atttgaattg aattttactt ggtttttgtg taagctagtc
     1501 atgaaaagaa ctcctttctt ttggttggtt tagtcacttt aaccatagca gaaaggggtt
     1561 cttttttcat cacttaacgg gtgaagatga aaaagtaatt gtaagctgcc gtgaggcagt
     1621 ttcacatggt tttaat
//
LOCUS       DADLIO010000165         1594 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.175, whole genome shotgun sequence.
ACCESSION   DADLIO010000165 DADLIO010000000
VERSION     DADLIO010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1594
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.175"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            288..695
                     /locus_tag="JOX41_002890"
     CDS             288..695
                     /locus_tag="JOX41_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450565.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            709..1110
                     /locus_tag="JOX41_002891"
     CDS             709..1110
                     /locus_tag="JOX41_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450566.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1112..1483
                     /locus_tag="JOX41_002892"
     CDS             1112..1483
                     /locus_tag="JOX41_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450567.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
BASE COUNT          596 a          201 c          277 g          520 t
ORIGIN      
        1 ttgaggggaa gtacatatag ttgttgatat agttgctaat attgttagct aatttgttag
       61 taaaactgta tacgaattta gatagtaaaa aaacagtttg ttccttatat agaggcactt
      121 ttactactga ttaaatgtca gatatgctta caaatatact tataaatatg cttacaaaat
      181 tagctaatat ttccgttgac aaagctttgt tactattgtt aaactaaatt gactagcaaa
      241 agtgaaacat aaatttatta aataaatgta aaaattagga gaaatcaatg tcttatagag
      301 tacaattaat aatttcagaa gatgtagaaa gtcagcaatt tggcactaat gttattaata
      361 aagtaattaa tccagctctt tctattaatg cgcctttaat tcctactgct ttatcatttt
      421 ctgtaacagc tgtggtgtct gagatagagg atacagaaaa gataaaaata gtagaaattg
      481 aagttttaaa caagaatgaa aaacaaattt tttctacggg tgaagtatcg gtaagcttgc
      541 ctcctcaagt taacgatata aactttaata taaacgccag aaatgtcttg gttgaagaag
      601 caggagagca ttatgctgtt gttaaattta atggaactga gattggaagg caaatctttg
      661 atatcaaggt caacaaacca gtggaaaaaa attaaggaga cgatacggat gcttgatata
      721 gtaccatcaa atacacatcg gagtggtagc ttaataaatt ttgctgcgat ttttgcttgc
      781 gcatcggtaa ttctagcatc tccagttgtt gtggatgcaa gttctactcc gaaaactaaa
      841 aatgataatc aacttgtaat tactacaaaa aatgagatta acacaatttc aagtaatgat
      901 ggcaaaattt ttgatgtgat aaatacggtt ttaaaaagaa aagctgaaat caatataaaa
      961 tatgatgaag atttaaactt gtatttcttt gttatcaaaa caacatctga attgttttcc
     1021 tcagattacg atgttttgga tactctcgat aatgtattat ctgactataa atatatgggg
     1081 aaatctgtag tagcaacttt gggggaataa aatgtttgac tttaatgaat atttatctat
     1141 ttccaaacaa attgaatcag atgataaata taattctaaa gaatcttata gaagaactgc
     1201 tgtttcaaga gcatactaca gtgcttttaa aaaatctgat gagtatttga aagaaaatta
     1261 tgatattatt tataatggaa gtagcggaaa aggaagccac caaaccgttt ggaatttgtt
     1321 ttcaacagtt aaggaattga ataccttagg aatacataat agtgggtata gaatgttaga
     1381 gaaaagaaaa tgtgctgact atattcctaa tgaaaccatt acgaaaacag atatggcgct
     1441 gatgaatcga gaagcagaaa aaataataaa caaactcacc taatgaattt caagcgagtt
     1501 tgtttgttat ttttttattt aatctttgta tctttctgga tcaacgaaag tatactttat
     1561 atagtcataa cgccgatgat cgctacgtgc gtcc
//
LOCUS       DADLIO010000166         1558 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.176, whole genome shotgun sequence.
ACCESSION   DADLIO010000166 DADLIO010000000
VERSION     DADLIO010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1558
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.176"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            132..344
                     /locus_tag="JOX41_002893"
     CDS             132..344
                     /locus_tag="JOX41_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450568.1"
                     /translation="MAVWQIQLKERGAYGLISLSDVLCRKEMPDLFSLDQIIAIIGAA
                     AVVITAVAKASDSILAWLKFKKEQKK"
     gene            506..1024
                     /locus_tag="JOX41_002894"
     CDS             506..1024
                     /locus_tag="JOX41_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
                     /protein_id="HAY6450569.1"
                     /translation="MDKFNRLTLINQFEILKALNPNEEKYYAEKIEILTEGYEYHYSE
                     IFENISDPLPEEDSRFVLDILNMYRDITFSKNKLKDINSIDNYYIQFKGFDFNSSTEF
                     KLALYAQFFIEKLNRFQEIVEDSDFNTFNSHKPMRGTYIKFLENYNDLKSTNNYQFGN
                     LSYEMISKVLSL"
     gene            1031..1543
                     /locus_tag="JOX41_002895"
     CDS             1031..1543
                     /locus_tag="JOX41_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450570.1"
                     /translation="MKLNSINDLFAIIGVIANILFSCLNFRFTQKNKKNKLSIEQMKK
                     DIETDLKNDHKERRKIEEYTSLMEKCKATDAIFSFLRKSDEIITRENIDLENEISKLE
                     SIFSDINSLKYLIVEENSDSFLEFEKYLTDLIDNRNNELMRQNIARFLTKLVSEWKSI
                     ISQNMDKLRY"
BASE COUNT          613 a          181 c          242 g          522 t
ORIGIN      
        1 aaaacactat atattccgaa aagtgagtat ctccattcat aaaataatca acatatttaa
       61 aaaatctaat tagctttttt agtcaatcta aagttcttta ttctatgata taatgttact
      121 gtagaaagtt tgtggcggtt tggcaaatcc aattgaagga gcgtggtgcc tatgggctta
      181 ttagcttatc ggacgtactc tgtagaaagg aaatgcctga tttgttctca ttggatcaaa
      241 tcattgctat tatcggagca gcagcagtag ttattactgc cgtagcgaaa gctagcgatt
      301 cgattttagc ttggttaaag ttcaaaaaag aacaaaaaaa atagagccgt ctcaactttt
      361 ggcgaggtag acgagctcta aagctttatt tacatgccat ccgctttgaa cggactacac
      421 tgggcatgtg acagcatgcc ctttcattta tattatatct cattctttta tataatgaaa
      481 gtaaataaat catggaggat aaaatatgga taaatttaat agattaacat taataaatca
      541 gtttgaaatt ttaaaagctt taaatcctaa cgaagaaaaa tactatgctg aaaaaataga
      601 aatactaaca gaaggttacg aatatcacta tagtgaaata tttgaaaata tttctgatcc
      661 attgccagaa gaagattcgc ggtttgttct agacatatta aatatgtata gagatattac
      721 ttttagtaaa aataaattaa aagatataaa ttcaattgat aattattata tacaatttaa
      781 aggttttgac tttaatagct ctaccgaatt taagttagca ctttatgcac aattttttat
      841 tgaaaaatta aataggtttc aagaaatagt tgaagatagt gattttaaca cttttaatag
      901 ccataaaccg atgagaggta cttatataaa atttctcgaa aattataatg atttaaaatc
      961 taccaataat tatcaatttg gaaacttgtc ttatgagatg ataagtaaag ttctaagttt
     1021 gtgatgataa atgaaattaa atagtataaa tgatttattt gctattatag gtgttattgc
     1081 taacatactt ttttcgtgtt tgaattttag atttactcaa aagaacaaaa agaacaaact
     1141 cagtatagaa caaatgaaaa aagacattga aactgattta aaaaatgacc ataaagaaag
     1201 aagaaaaatt gaagaatata cttctttaat ggaaaagtgt aaagcaactg atgcaatttt
     1261 tagcttttta agaaaaagtg atgagataat cacacgtgaa aatatagatt tagaaaatga
     1321 gattagtaaa cttgaatcta tcttttccga tataaattct cttaagtatt taatcgtcga
     1381 agaaaattcg gatagctttt tagaatttga aaaatatcta acagatctta tagataatag
     1441 aaataatgaa ttaatgagac aaaacattgc aagattcctt actaaattag tttctgaatg
     1501 gaaaagtatt atttctcaaa atatggataa attaagatat taaggatgtt agttttaa
//
LOCUS       DADLIO010000167         1536 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.177, whole genome shotgun sequence.
ACCESSION   DADLIO010000167 DADLIO010000000
VERSION     DADLIO010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1536
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.177"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(<1..>1536)
                     /locus_tag="JOX41_002896"
     rRNA            complement(<1..>1536)
                     /locus_tag="JOX41_002896"
                     /product="23S ribosomal RNA"
BASE COUNT          321 a          476 c          337 g          402 t
ORIGIN      
        1 gggaaatctc atcttgaggt gggcttcaca cttagatgct ttcagcgttt atcccttccc
       61 tacatagcta cccagcaatg cccttggcag aacaactggt acaccagcgg taagtccatc
      121 ccggtcctct cgtactaagg acagctcctc tcaaatttcc aacgcccgcg acggataggg
      181 accgaactgt ctcacgacgt tctgaaccca gctcgcgtgc cgctttaatg ggcgaacagc
      241 ccaacccttg ggaccgacta cagccccagg atgcgacgag ccgacatcga ggtgccaaac
      301 ctccccgtcg atgtggactc ttgggggaga taagcctgtt atccccaggg tagcttttat
      361 ccgttgagcg atggcccttc catgcggaac caccggatca ctaagcccga ctttcgtccc
      421 tgctcgactt gttggtctcg cagtcaagct cccttctgcc tttacactct tcgaatgatt
      481 tccaaccatt ctgagggaac ctttgggcgc ctccgttacc ttttaggagg cgaccgcccc
      541 agtcaaactg cccatctgac actgtctccc accacgatta gtggtgcggg ttagagtggc
      601 cataacgcag gggtagtatc ccaccagcgc ctccatcgaa actagcgttc cgatttctac
      661 ggctcctacc tatcctgtac atgcggtaca gacactcaat atcaaactac agtaaagctc
      721 catggggtct ttccgtcctg tcgcgggtaa cctgcatctt cacaggtact aaaatttcac
      781 cgagtctctc gttgagacag tgcccaaatc gttacgcctt tcgtgcgggt cggaacttac
      841 ccgacaagga atttcgctac cttaggaccg ttatagttac ggccgccgtt tactggggct
      901 tcaattcgta ccttcgcttg cgctaagcac tcctcttaac cttccagcac cgggcaggcg
      961 tcagccccta tacttcatct tacgattttg cagagacctg tgtttttgat aaacagtcgc
     1021 ttgggcctat tcactgcggc tgatcgtatg atcagcaccc cttctcccga agttacgggg
     1081 tcattttgcc gagttcctta acgagagttc tctcgctcac cttaggattc tctcctcgac
     1141 tacctgtgtc ggtttgcggt acgggccgct gttttctcac tagaagcttt tctcggcagt
     1201 gtgacatcag gaacttcggt actattattt ccctccccat cacagcttgt ccttaagaaa
     1261 agaagcattt gactcctctt cagacttact gcttggacag acatttccga tcgtctgcat
     1321 tccttagcct cctgcgtccc tccattgctc aaacaaaaac aacgggtaca ggaatatcaa
     1381 cctgttatcc atcgcctacg cctgtcggcc tcggcttagg tcccgactaa ccctgggcgg
     1441 acgagccttc cccaggaaac cttagtcatt cggtggacag gattctcacc tgtctttcgc
     1501 tactcatacc ggcattctca cttctaagcg ctccag
//
LOCUS       DADLIO010000168         1529 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.178, whole genome shotgun sequence.
ACCESSION   DADLIO010000168 DADLIO010000000
VERSION     DADLIO010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1529
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.178"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(52..1518)
                     /locus_tag="JOX41_002897"
     CDS             complement(52..1518)
                     /locus_tag="JOX41_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HAY6450571.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT          499 a          324 c          289 g          417 t
ORIGIN      
        1 aaaaaacagg aactgctgca aataagcaat tcctgttttt atgttcattg attaatgaat
       61 agagcccatt agttttttga ttggttcttt cacagtaaat agcaagatac caccgacgat
      121 tgctactgca ccgataatac cgaagtaagc agattctgtt cccggtgtgt agaagcgtgc
      181 aatttgtgca ttgattgctt gtgaagaagc atcagctaag aaccaaatag cgattgtttg
      241 tgattcaaat gctcgtggtg ctaattttgt tgtcacagac aaaccaactg gtgaaagaca
      301 caattcagca ataaccacga tgaagaaact tcccaacaac cacaatggac ttacttttcc
      361 acttgtacca taaagcatac ccggcaacat caatagcaag tacgataatc ctgcaaataa
      421 aagtccaaga gagaatttca ctactgtaga tggttgacgt tcaccaagtt tcgtccacat
      481 cgttacgaat actggtgtca gaataaagat gaaaattgga ttcaatgatt gataccagct
      541 tgcttggatc gttacaccaa atagcgtaga ttgtgtacgt tcactagcaa ataaagctaa
      601 gatagatgaa ccttgttctt gtaatgacca gaaaatgatt gctgcaagga ataatgggat
      661 ataagcccat actcttggtt tttcttcagc agttacatct tttgaagtca gcattttgat
      721 aaagtaatac aacggtaaga taatccccaa tacactgatt gtattgacaa aaaagtcaat
      781 tgtcagatga ccagttagtt gtgccccgcc gaatactgca gcgataacaa caagtgcgat
      841 gatcaagtta cggatgaatc ctttacgttc ttcagttgtc aaaggattcg gcggtgttgt
      901 acccactccg tctaatgtct tgcgtccttg gatgatgtat tgtaataatc caaagaacat
      961 cccaatagca gctaaagaga accctaaatg atagttatat tcttgaccga ttgtaccaac
     1021 gattagtggt gctaataatg cccctaagtt gacacccatg taaaaaatcg aaaatcctgc
     1081 atctcttcgc aagtcagtct ttgaataaag atgtccgacc atgccagaaa catttggttt
     1141 caaaaaggcg gttccgataa taatcaatgc catcgaaaca aacaatgtac ttacaccaaa
     1201 tggtaaagcc aagacgatgt ggccaagcat aatgaaaact ccaccgaaga atacagtgcg
     1261 ttttgctcct aacactcggt cagataccca tccgccgacg atactagaca tgtagatcaa
     1321 agatccgtag atcgacatga tagctaatgc tgttgctcgt ggtaatccaa gtcccccgtt
     1381 ggcaactgta tcgtacatat aatagataag taatgcacgc ataccgtaat aactaaatcg
     1441 ttcccacatc tcagtgaaga acaaagttga caatcccttc ggctgcccga agaagccctt
     1501 gtcttgctgt ttttccataa tctataccc
//
LOCUS       DADLIO010000169         1440 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.179, whole genome shotgun sequence.
ACCESSION   DADLIO010000169 DADLIO010000000
VERSION     DADLIO010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1440
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.179"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            105..1406
                     /locus_tag="JOX41_002898"
     CDS             105..1406
                     /locus_tag="JOX41_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAY6450572.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT          474 a          288 c          264 g          414 t
ORIGIN      
        1 gatagaaaat cattctatcg gtcccttttg agcatgaaaa aacaaaacat acagaagctc
       61 cgttagaatt gaatcaccac aacacaatca aaggagcgtt ctgtatgcct gatcttcatc
      121 atatcaaact actacttgga atcaaagata aaaacatttt catcacaaat gtggaatcga
      181 agagcattaa gaatatcaag agtcttgttg tttctgcgac gttaagtaaa gaaattcgtc
      241 gctgtccttt gtgtaaacag atgaatcatg aaggcatgat cgttaagaac ggaaagaaaa
      301 aatcgctcat tcaacttaat aaatgtgcga accaactgac ttatcttgct ttagcgaaac
      361 aacgctacca ctgtcgtggc tgccacacct attttacggc gaatacctac attgtcgata
      421 gaaactgctt tatcgctaaa caagtgcgct ataaaatttt agaagagcta actgaaaaac
      481 aagcaatgac gacaattgct aagcattgcg gcgtttcttg gtcgaccgtt tctcggacac
      541 tcgcttctct gatccccatg acaaaagtaa aaagaaattg gttaccgcgt tgtttattaa
      601 tggatgaatt tcgttcactg aaaaatcaag tcggtcccta ctccttttct tgtatggatg
      661 gcgatactgg aaaattactg gatattcttc cttcacggaa gaaaaaggct ctcgtttctt
      721 attttatgca atttgaacga cgcgcacgat tgaaggtaaa ggtcatcgtg acggacatga
      781 atgtttctta tgcctctctg ataaaggaat gttttccaaa ggcaaaactc gttgtggatc
      841 gttttcacat tgtcaaacat ctcattcgta aatttgagga tattcgcgta cgaatcatga
      901 aaagctttga tcgaaacgat ccaacacaag ccaaatatta tcgacaatta aaggcgttgt
      961 ctcggcttct gatcaaacga caggacaagc ttgtttatga caaatggacc aaatggcgca
     1021 attttggttg ggcgtatctc accgaaagtg aagtggtgga tcgtctgctt tcgatctctg
     1081 acgaattacg aatcgcctat ttttactatc aagaaattct tcaagcgttt cacgacaaag
     1141 aggcggacac tttctttaaa cttgtaagaa cgatgcccaa ttccgttcca aaagaactgc
     1201 attctataaa aaaagctttt ataaactatg aatccggcat tcgtttagcc ctcgaattgc
     1261 cttattcaaa tgccaaaata gaaaatctgc atacccacat caaagcattg aaacgagtcg
     1321 cttatggctt tcgaagcttt cggaaaatga agaccagaat tttcttacta aataatctga
     1381 ttacctatga atcaaaaaac atctaaagta gaaaaggaat tctaccttag atgttcttat
//
LOCUS       DADLIO010000170         1417 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.180, whole genome shotgun sequence.
ACCESSION   DADLIO010000170 DADLIO010000000
VERSION     DADLIO010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1417
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.180"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            52..1344
                     /locus_tag="JOX41_002899"
     CDS             52..1344
                     /locus_tag="JOX41_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAY6450573.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFKLRIMIRHSKTFLT"
BASE COUNT          444 a          285 c          271 g          417 t
ORIGIN      
        1 cctgaaatcc tttagaatta atttggctac caattcatag gaggattcaa gatgtctcat
       61 actcagctta tcaaagatac cctaaatatt ctagacctaa atatctattt cgaggaaaat
      121 tgtttaacta aagaaaaata caaagggcaa atttgcttga tttacaaagg aactcttctg
      181 tacaagccag aagagtgttc ccattgtctt tgtgtcgtcc cctctaggat cattcgttgg
      241 gggacgacaa ccgttcggtt gttactgaat gatgtgtctg agtatcgcac ttatctggag
      301 ctgaagaaac aacgatttaa atgtaagtct tgccaaagaa cattcgtagc ggatacctct
      361 gttgctgaaa aacactgttt cattagtcaa aaagttcgtt ggtctgtcat tgctcgctta
      421 aaagagaata cttccatgac ggaaatcgct cgtcagaaaa atatttccac ttcttcggtc
      481 tatcgtgtca tgaagcgatt ctaccgccca ttgaatcctt tcaaacagac tttgccaaag
      541 gtcttatgct ttgatgaatt caaatcggtt cgaagtgttg ccagtgcaat gagttttatc
      601 atgatggacg gacaaagcca tgcattattg gatattgtcg aaaatcgacg cttgccttat
      661 ttagaacgct atttttctcg gttttcatta gcgactcgtg aagccgttca attgattgtt
      721 attgatatgt atgcgcctta tgtttcgttg gtgaaaaagc ttttcccgaa tgctcagttg
      781 atcatcgatc gtttccacat cgtccaacat attggcagaa ctttcttgaa tcatcgagtg
      841 aaagaaacca cggtacgact taaaggaaat tcccactctc aacgagggtt agggaaaaaa
      901 ttgaagcgct attggaaact cctacaaaaa gaagaagcaa agttaaacta tgaaaaacgg
      961 gtttggcgtg ccagttttaa agattatttg actgaaagtg agattgccga tcgactgtta
     1021 gctgcttgtc ccaacttacg ccaaggctat cagttatacc aagacattct ttatgcggta
     1081 aagaaaagag atcagtcact atttgaggat tgtttaacta gagacattag cggtctgcca
     1141 gaaacctata caaccacttt acgaacgttt aaaaagtttc tgccacagat ccaaaatgcg
     1201 cttcactaca gctattcaaa cggaccattg gaatgcttaa acaaccacat caaagtatta
     1261 aaacgcaatg cgtacggctt tcgcaacttt tacaatttca aactacgaat tatgattcgt
     1321 catagcaaaa catttttaac gtaagcgccc catagaacag taccttacta acaaatgcac
     1381 ctcaagatat acttgagcta tcaagaagtc tggaggt
//
LOCUS       DADLIO010000171         1417 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.181, whole genome shotgun sequence.
ACCESSION   DADLIO010000171 DADLIO010000000
VERSION     DADLIO010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1417
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.181"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(150..1337)
                     /locus_tag="JOX41_002900"
     CDS             complement(150..1337)
                     /locus_tag="JOX41_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HAY6450574.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          412 a          308 c          249 g          448 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttc
//
LOCUS       DADLIO010000172         1366 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.182, whole genome shotgun sequence.
ACCESSION   DADLIO010000172 DADLIO010000000
VERSION     DADLIO010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1366
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.182"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            82..>1366
                     /locus_tag="JOX41_002901"
     CDS             82..>1366
                     /locus_tag="JOX41_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HAY6450575.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQLI"
BASE COUNT          466 a          263 c          257 g          380 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atcaatcaat taatca
//
LOCUS       DADLIO010000173         1363 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.183, whole genome shotgun sequence.
ACCESSION   DADLIO010000173 DADLIO010000000
VERSION     DADLIO010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1363
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.183"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            5..403
                     /locus_tag="JOX41_002902"
     CDS             5..403
                     /locus_tag="JOX41_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HAY6450576.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            387..1082
                     /locus_tag="JOX41_002903"
     CDS             387..1082
                     /locus_tag="JOX41_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HAY6450577.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
BASE COUNT          520 a          203 c          273 g          367 t
ORIGIN      
        1 agagatgacg atctttgaaa cggttgtaac agatgttggt atagaagcag aagtattcag
       61 gaaagaaaaa ataatgattt tatttggaga tgaagcaccg gaaacattaa cagattattg
      121 ttataagatt gaattgaatc aggtaagaaa agaaataact tgtgatatga agctctgttt
      181 tgataaacaa atgtatgtaa tcacagcagt aggagatgtt gtccaaacta atttgaatga
      241 attaggacat atcacgataa aatttgatgg atctcatgag ccggaacttc caggaacaat
      301 gtatgtagaa gataaggaaa tgccgcattt aagaaagggg acaatcatta aaatcgatca
      361 agaggatcag aatgggggaa agctatatgg aaatcatgct tgatacagca aatacaaaaa
      421 gtatttattc ttgtcaacag tttttgaatt taacaggcgt aacaacaaat cctacaattc
      481 tgaaaaaaga aggagcgtca aacttcttct cgcatatgaa agaaatcaaa aaaataatcg
      541 gacagattcc tatccatatt cagacaatag gaagaacgga agaagaaatg atagaggatg
      601 ctcgagttat catagaagaa ctgggaaaag atacgtttat caaggtgccg gtgaatcaag
      661 caggccttca agcgatcaaa aagttgaaaa aagaaggtta tttgattacc ggtacagcta
      721 tttacacaga attacaaggg tatttagcta ttaataatgg agcagattat attgcacctt
      781 attataacag gatgcaaaat caaggcattg atgctatgaa agtgattgat tcgttgcgga
      841 ctgagatcga acgtacgcaa agaccaacaa aaatattagc agctagtttc aaaaattgtg
      901 aacaagtcac tacagccatt cgatctggag ctcatgcgat aacgttaggt aaagagctac
      961 tagatcaagt attagagatg ccctcgattg ataaagcagt gaggggcttc caagaagatt
     1021 gggtgcaaac tttccaagca gaaacgattg gtgaactaaa aaaggtcgct gattacttct
     1081 gaatcaattt ctccataaaa taaacgatag ccttctcgaa aactcgagga ggctatctga
     1141 cgattcaata ttcattaatt taaagtttgg gtgactatta ctaactatta cttatttctc
     1201 atttaaacga tgtattccct aacctctaat acatccttgt aactctgaag ttacgccagt
     1261 tttgaataaa tttcataaaa acaaatgaaa agtgtcgcat aaaaatatct ttcgtgtttc
     1321 tctagtataa cagaataaga agaacaagtc cagaagggat att
//
LOCUS       DADLIO010000174         1359 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.184, whole genome shotgun sequence.
ACCESSION   DADLIO010000174 DADLIO010000000
VERSION     DADLIO010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1359
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.184"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(<1..208)
                     /locus_tag="JOX41_002904"
     CDS             complement(<1..208)
                     /locus_tag="JOX41_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450578.1"
                     /translation="MSIDDCLEEQIRLFLKFLKVKVQNNYFTCYSYAHPVLNSLPFNS
                     LVQGLITNIVLLVCTPNEIFVKKIG"
     gene            complement(305..757)
                     /locus_tag="JOX41_002905"
     CDS             complement(305..757)
                     /locus_tag="JOX41_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450579.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVFNYSLTRINYKEITKFSLEKVPFWG
                     EFCLKIKCNWKRMYFYIDGDDALTFGKTTFSSFNFQFLLKNNFYGLLK"
     gene            complement(764..1312)
                     /locus_tag="JOX41_002906"
     CDS             complement(764..1312)
                     /locus_tag="JOX41_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAY6450580.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
BASE COUNT          487 a          264 c          132 g          476 t
ORIGIN      
        1 tgcctatctt ttttacaaat atttcatttg gtgtacagac taataaaaca atatttgtaa
       61 tcaatccttg cactaaagaa ttaaaaggaa gactatttaa aacagggtgt gcataactat
      121 aacatgtgaa gtagttattt tgaactttaa cttttaaaaa ctttaaaaat aatcttattt
      181 gttcttctaa acaatcatct atactcatat aatcactcca ctaattaatc tccccaaaaa
      241 gacacagcat taagagatat accaacacaa cagtgcaaat aactctacat cttccttcgc
      301 aaccttattt caataaacca taaaaattat tttttaatag aaactgaaaa ttaaaactag
      361 aaaaagtagt tttaccgaat gtaagagcat catcaccatc aatatagaaa tacattcttt
      421 tccagttaca tttaattttt aaacaaaatt ctccccaaaa aggaactttt tctagtgaaa
      481 acttggtaat ctctttgtaa ttaattcttg ttaaagaata attaaacact tcatttttac
      541 ttgttatttt ttcattgact ataactagtt catctggtaa aaaaattaac caacaaacat
      601 cgacaaacag taaatgatat aatccatttc cacctccaag catattcaat actggtgaac
      661 atgccttaga aacacgaata tagttatggt ttaaatagat attttcttta aacattgctt
      721 gtttaaaagc catatgctct tgttctaaac ttttcataaa cttttactct aatgcacagc
      781 tagcagcagc tgctgcaatt cctgctacaa tatttacctt agctaactct ttagctgcag
      841 cttttcctaa ttgtttttct gcaattttta ataataaatc cgcagctttt tcaaaattaa
      901 aagcttttaa tgcttcaata aaatctccct gcgtacctat agcccaagcc actcctcctc
      961 caggaagaga attaatggct acacatccag catatcgttt ccaatcaact ttctccattc
     1021 taggaacaat aatatgttca taaaagactc ttgctgctct tccttgttcg ttatcttgac
     1081 tgattcgttc acgaatagca ccaaaatcct ttatatggta tacaccatgt tcgtctaaaa
     1141 aaccaactgt atcaaaataa aaagttaatt catctactaa tttattcttt atttctaaat
     1201 caactgtatt cactttttct gtggcataca cacttgttcc agtactaaca aaagtactta
     1261 aacctaataa gaaaacacct aaaacaccaa atattttaat tattcttttc ataatttctc
     1321 ctccataaaa aataagttac tttttaaata tcttgttta
//
LOCUS       DADLIO010000175         1343 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.185, whole genome shotgun sequence.
ACCESSION   DADLIO010000175 DADLIO010000000
VERSION     DADLIO010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1343
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.185"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            160..897
                     /gene="erm(B)"
                     /locus_tag="JOX41_002907"
     CDS             160..897
                     /gene="erm(B)"
                     /locus_tag="JOX41_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HAY6450581.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTITYEQVLSIFNSYLLFNGRK"
     gene            1067..1327
                     /locus_tag="JOX41_002908"
                     /pseudo
     CDS             1067..1327
                     /locus_tag="JOX41_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase"
BASE COUNT          514 a          222 c          219 g          388 t
ORIGIN      
        1 aacagactaa aaacagtgat tacgcagata aataaatacg ttagattaat tcctaccagt
       61 gactaatctt atgacttttt aaacagataa ctaaaattac aaacaaatcg tttaacttct
      121 gtatttgttt atagatgtaa tcacttcagg agagattaca tgaacaaaaa tataaaatat
      181 tctcaaaact ttttaacgag tgaaaaagta ctcaaccaaa taataaaaca attgaattta
      241 aaagaaaccg ataccgttta cgaaattgga acaggtaaag ggcatttaac gacgaaactg
      301 gctaaaataa gtaaacaggt aacgtctatt gaattagaca gtcatctatt caacttatcg
      361 tcagaaaaat taaaactgaa tactcgtgtc actttaattc accaagatat tctacagttt
      421 caattcccta acaaacagag gtataaaatt gttgggaata ttccttacca tttaagcaca
      481 caaattatta aaaaagtggt ttttgaaagc cgtgcgtctg acatctatct gattgttgaa
      541 gaaggattct acaagcgtac cttggatatt caccgaacac tagggttgct cttgcacact
      601 caagtctcga ttcagcaatt gcttaagctg ccagcggaat gctttcatcc taaaccaaaa
      661 gtaaacagtg tcttaataaa acttacccgc cataccacag atgttccaga taaatattgg
      721 aagctatata cgtactttgt ttcaaaatgg gtcaatcgag aatatcgtca actgtttact
      781 aaaaatcagt ttcatcaagc aatgaaacac gccaaagtaa acaatttaag taccattact
      841 tatgagcaag tattgtctat ttttaatagt tatctattat ttaacgggag gaaataattc
      901 tatgagtcgc ttttttaaat ttggaaagtt acacgttact aaagggaatg gagataaatt
      961 attagatata ctactgacag cttccaagaa gctaaagagg tccctagcgc ctacggggaa
     1021 tttgtatcga taaggggtac aaattcccac taagcgctcg ggaccccttg taggaaaatg
     1081 tcctaagtgt ggcaacaata ttgtattaaa aaaatcgttt tatggttgtt caaattatcc
     1141 tgaatgtaag tttactttag ctgaacattt tagaaagaaa aaactaacca aaacgaatgt
     1201 aaaagaatta ctggagggaa aagaaaccct ggtaaaagga atcaaaaaca aagagaaaaa
     1261 gccctacaat gccgttgtaa aaattgggga aaagggatat attgatttta tctctttttc
     1321 aaaataaaca taaaagccct tta
//
LOCUS       DADLIO010000176         1318 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.186, whole genome shotgun sequence.
ACCESSION   DADLIO010000176 DADLIO010000000
VERSION     DADLIO010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1318
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.186"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            188..391
                     /locus_tag="JOX41_002909"
     CDS             188..391
                     /locus_tag="JOX41_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450582.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            602..1186
                     /locus_tag="JOX41_002910"
     CDS             602..1186
                     /locus_tag="JOX41_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAY6450583.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT          465 a          183 c          252 g          418 t
ORIGIN      
        1 agtgacagga acgatgattt ttgataaagt tggttggcct tctagacctc ctcaatcacg
       61 gaattggaaa gaaaaaagaa atggttattg gtactatgga aaattgtatt tacaaagtta
      121 taaatcagct ggaaacaatt ggattgcgac ttattcagga accttaacta gaaagtaggg
      181 attttttatg ccagaatttg tgaacacacc aaatttttat caagatagcg atattctaag
      241 taaaattaat ttaccgaaag aagaatcagc tttacaagtt cagcgaactt tacaggagac
      301 acaaaaaatt caaaaatcaa tttctaatct agaagattct gaagaaaaaa gaaaaaaaag
      361 agaccaaaaa acatatcaaa aagaaaaata atgattttaa aaaaagagtg tctagtcgac
      421 attctttttt tctaattgaa agtgttcata aaatcaccca tttctggaca cttccttttt
      481 ttgctttatt tttcaaaaaa acaattcatt tcatgttcat aaacccataa caatatctat
      541 gttcagttaa actatatgga taaagttatg ttacaataaa attaatgaag gagtgatttt
      601 tttgaaaata ggatacgccc gggtatctac tggtttacaa aatttggatt tacaagaaga
      661 cagcctaaat aaatttggtt gtgaaaaaat ttttactgat catatgagtg gggcaaaaag
      721 taatcgacca ggattagaaa tggccattga ttttgttcgc tctggcgata cacttgtcgt
      781 ttggcgctta gatcgtttag gtagaaatat ggaagatttg atttcaatcg tcaatcgact
      841 gaatgagcgt ggtgtgagtt ttcatagtat tcaagaaaat attacgatgg acaaatcaag
      901 ttctacagga cagctcatgt ttcatttgtt tgcggcattt gcagaatttg agcgtaattt
      961 gatcctggaa cgatccgcag caggacgagc agctgctcgt gcaagaggac ggtttggtgg
     1021 tcgtcctgaa aaattgtctg aacaagattt ggaattactg aagactttag tggatagcgg
     1081 tacacctatt aagactattg cggaacggtg gaacgtctca agaaccacca tttatcgtta
     1141 tttggcaaaa atggaggaga aaaatggaaa gacaaattct cattagtttt tgtcatttaa
     1201 tgctgaaaat ttttgccatt tatctagaaa agtgacaata gtatgagaat tttttgtaag
     1261 tgtctactga taacttattc tcaaatgttg taaggatttt attcatttgt taatatta
//
LOCUS       DADLIO010000177         1297 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.187, whole genome shotgun sequence.
ACCESSION   DADLIO010000177 DADLIO010000000
VERSION     DADLIO010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1297
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.187"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            141..398
                     /locus_tag="JOX41_002911"
     CDS             141..398
                     /locus_tag="JOX41_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450584.1"
                     /translation="MSKLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(630..1043)
                     /locus_tag="JOX41_002912"
     CDS             complement(630..1043)
                     /locus_tag="JOX41_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HAY6450585.1"
                     /translation="MDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVLSASIPI
                     LIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEKLLYITK
                     TSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          492 a          169 c          161 g          475 t
ORIGIN      
        1 ttctgtccac gttcatatta ctccaaagtt ttcctcattc caaaagaaaa gcacagaata
       61 cacaaagaag cgtttttatt tgtataaact atatcaaagt tctatactta aattatcaaa
      121 taaaaaggac gtgaagataa atgtcaaaat tagaaaacaa agaagaaaaa gttgtaaaca
      181 aaattgtttc tgttgtcaat aaactggata aagagttaga cgaacttgat acgttatctg
      241 aaaatccaga aaaaaaacat aacctaaaaa aatggttagt tgaacgaaag gctattcatg
      301 aaattaaaaa agttcttcat gaagctgata aatatgaaaa atatgatgaa aaagaacttg
      361 acaaagaatt taaagaaatc aatgacttat tactataatt gatttatacg actcattttt
      421 gagtcgtcag actgcaaaca acactctaaa tttaggagtt tgtctacagt ctgaataaat
      481 tttaaattta ttgtccataa tgttattatg aatttatagc attaagaaaa gagataagac
      541 tttacatttt tttaggaatg taaagtctta tctcttttct taattgtaca attagtatta
      601 tctgcactac tttctaatta aataaatttt tagttattaa cttgattaaa atcagagata
      661 atatcattta attcagtttg aagggttgta acgattaaat ggaaattttc ttcatctgtt
      721 ttattatatg gggatgtttt cgttatatat aacaactttt ctttttcaat tttcattaat
      781 aactctgtcg aagtctgtac tttatcttga taattaaatg cagacatccc actttgtata
      841 attgtaatta ttgctgaagc aattgaaaca atcaatagta aagacctgtg ttcggaagcc
      901 tgatcaatta atattgggat actagctgat aagactattt ttataatatt tccgatacca
      961 attactctat tataaaatcg aatttctttt tttaatctat cgattgtaga atcaatagat
     1021 tcgataaacg ctttttgatc catcattttc tctccaatca ttttattaaa atcattaaca
     1081 aaaatattat aataggattt aagtaagttc taactaatca cacataaaaa taaaaaacat
     1141 ttgtatttta tcaaagtttt attatacttg tcaatttgtg tacatcctaa aatataagct
     1201 atttgtttac ttctgtagaa tatatacttt gttgttagat aagttgcaca tgtttataga
     1261 atctaaataa taaattttta tgtaccgccc ctccaaa
//
LOCUS       DADLIO010000178         1284 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.188, whole genome shotgun sequence.
ACCESSION   DADLIO010000178 DADLIO010000000
VERSION     DADLIO010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1284
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.188"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(37..705)
                     /locus_tag="JOX41_002913"
     CDS             complement(37..705)
                     /locus_tag="JOX41_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAY6450586.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            839..1126
                     /locus_tag="JOX41_002914"
     CDS             839..1126
                     /locus_tag="JOX41_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450587.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
BASE COUNT          479 a          215 c          215 g          375 t
ORIGIN      
        1 tttctgtaaa ttaaataaag tagtgaaaaa taagaatcag tgctctaact gttcaagagg
       61 atcaagtggt tcaaatgttt ctgtagtctg ttttgcttcc aattggggca aaacagatcc
      121 aatttccaga tacttcactt tattcaatgt ataagataga atagaacagc taagtaatgt
      181 atacagaaaa tgtgtgagat ccaaataaag caaggagaca actaaaatac caaaagtaat
      241 caagaaaaga cttttgccaa tcttaatatg aaaatatttt tcaatggctt gataaatgat
      301 atctgttccg cctgtgcttc cgccgaatcg aaagacgaga ccgcaaccaa tgccagaaag
      361 aatacctgtc atcaaactat tgatcagtag actatctaca gcaaaatgta tatgaaggct
      421 ctcccataaa tgtaaaaaga aaactagcgc aaatgttccg acgatcgtcc ggagaaaagc
      481 gtgttttcca aaaagaaaca atgagataag caataaaggt aaattaaaaa gcagtgaagt
      541 gacagaagga gcgaatccaa aaagattatg caaaagcaaa gcaataccag taaccccacc
      601 atctgccagc ttagatggaa tattgattcc tgtcacagct aatccgtaga ttcctgcgcc
      661 taaaatgatt ccgcacaatt ctgtaaataa atttaatttt ttcatttcta gcctcttttc
      721 ttttgaaaat tttcagcaac ttctttatta tactgactta tactcttact tcaagaggaa
      781 aatgaaaaaa aattattttt ggctgtttct ttttatttat caaataagga gtggaaaaat
      841 gcgagcagca gacttattga caattcttac aaaatcaccc aaaaaaacag agtatcaagg
      901 agtttttttg gctcaagaac aaaaactggt gcctgtgaca atggtccaga taaataaagc
      961 aaatcaattt atctttttat ttgaacacgg caaagcacca cttgctatga aagacatctt
     1021 tctttttttg atgaagaacc gtgagaaagc tgtttattat cagtcaaaag aagaactcat
     1081 tcctctttat ggagtgaaag agatagaaaa taaagtggtg atataagtaa aaataagaaa
     1141 acaagacgtt tatgatgtca aaacaaccat tttttacatt tttggcaaaa aagtgtcatg
     1201 atacagtata atattcgttg aacaggccaa taaaggtgtt ctcccccacg agatttctac
     1261 tttattggct gtttcttttt atta
//
LOCUS       DADLIO010000179         1275 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.189, whole genome shotgun sequence.
ACCESSION   DADLIO010000179 DADLIO010000000
VERSION     DADLIO010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1275
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.189"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(31..1203)
                     /locus_tag="JOX41_002915"
     CDS             complement(31..1203)
                     /locus_tag="JOX41_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006701269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS1542 family transposase"
                     /protein_id="HAY6450588.1"
                     /translation="MTQVHFTLNNEEVQSIIEHSVKDDVSKNILTTVFNQLMENQRTE
                     YIQADDYERSESRQSQRNGYYERDFTTRVGTLELKVPRTRDGEFSPTVFERYQRNEKA
                     LLASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLDPMVNEWQNRSLSGTN
                     YPYLMTDVLYIKVREDHRVLSKSCHIAIGITEGGDREIIGFMIQNEESDDTWSIFFEY
                     LKERGLKGTELIISDAHKGLVSAIRKSFTNASWQRCQVHFLRNIFSSIPKKNSKPFRE
                     AVKAIFKFTDIELARTAKNALVGEYIDQPKYTKACEILDNGFEDAFQYTVIGNSHNRL
                     KSTNLLERLNQEVRRREKIIRIFPNRTSANRLIGAVLMDLHDEWLSSTRKYIKFDQ"
BASE COUNT          345 a          265 c          245 g          420 t
ORIGIN      
        1 taaaatacta tacaatgttt taccggtctc tcattgatca aacttaatat attttcttgt
       61 agaactgagc cattcgtcat gaaggtccat aaggacagct ccaattaatc gattggcaga
      121 cgttcggttg ggaaaaatcc gaataatctt ttctcttctg cggacttcct ggttcagtcg
      181 ttcaagaagg ttggtgcttt ttagccgatt atgactattt ccgataaccg tgtattgaaa
      241 ggcatcttcg aagccattat ccaatatttc gcaggctttt gtatatttag gctggtcgat
      301 atattcaccg actaaggcat tcttagctgt tcgagcgagt tcaatatccg taaacttaaa
      361 gatcgctttt actgcttctc taaacggttt tgaattcttt tttggaatgg aactgaagat
      421 gtttcttaaa aaatggacct ggcatctctg ccaacttgcg ttggtaaatg acttacgaat
      481 cgcagacact aggcctttat gggcatcaga aatgatgagt tctgtcccct ttaggccgcg
      541 ttcttttaag tattcaaaga agatggacca tgtgtcatca ctttcttcat tttgaatcat
      601 gaagccaatg atttcacggt cgccaccttc tgttatcccg atcgcaatat ggcagctttt
      661 agaaagcact cgatggtcct cacggacttt tatgtagaga acatcagtca tcagataagg
      721 ataattcgta cctgagagtg aacggttctg ccattcgttg accatcgggt ctaactgctc
      781 agtcaggcta gaaacaaaag atttcgatac agattttcca catagctctt caacaatctt
      841 tgaaacttta cgtgtcgaaa cgcccgaaac atacatctca agcattgaag cgagcagtgc
      901 cttttcattt cgctgataac gctcaaacac cgtcggtgaa aattcaccat cacgtgttct
      961 aggcactttt aattcgagtg tacccacacg agtcgtaaag tctcgctcat aatagccatt
     1021 tctttgactc tgacgacttt ctgaacgttc atagtcatcg gcttgaatat attctgttcg
     1081 ttgattttcc atcaattggt tgaaaacagt ggttaaaata tttttagaaa catcatcttt
     1141 taccgaatgt tcaataatac tttgaacctc ttcgttgttc agtgtaaaat gtacttgggt
     1201 catgtaacgt cctcctgggt atgtttttgt ggttaaaaac attgtaccgt aaaagggctg
     1261 ttacatggcc tttta
//
LOCUS       DADLIO010000180         1251 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.190, whole genome shotgun sequence.
ACCESSION   DADLIO010000180 DADLIO010000000
VERSION     DADLIO010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1251
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.190"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            285..1100
                     /locus_tag="JOX41_002916"
     CDS             285..1100
                     /locus_tag="JOX41_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450589.1"
                     /translation="MVKIAGLSKGGKTVSQLYKQNYRDWRQFRKNIKDSYFILPTELE
                     KYLPNNKAINLYLYYCFKAKNEGGDSWHSVNTIAESLGVTTKTINTWNKTLVDLGMIA
                     RIDDNHLSKSTILLPLSSYYKLALDSSLKDVTESTVHEIDGNLVAVYHLFEWRKNEAD
                     ENYNVPYNTLCCVFKRKTQKDTIYKFILVQDEKISNFELSTPSSKIYDDAYRFECQDL
                     EALLSANNLNNIEHENFVVNTRFNLVSEKDSDLLDLLIELTKNLDKKENITVL"
BASE COUNT          481 a          172 c          202 g          396 t
ORIGIN      
        1 ataagaaatt caaaaaagaa aaaactttcc ttaaaaacaa aaaataggag tattcagttt
       61 cttaatagtt ttgtaatagt tgtatgtaga agttttctta atagtttttg taataattta
      121 ttaatcgtag tttatataac ttatttgtaa gtgactagag aattaaataa aaaataatta
      181 ctatctagta cgaaattaat tacataggat aatatattaa ggtgctggac tacaagtaaa
      241 aaatactgta tgatcatgac agattcaaga aaggagcaat aagattggtt aagatagcag
      301 gactttctaa aggtggaaaa accgtttcac aactttataa acaaaactac agagactgga
      361 gacagttcag aaaaaacatt aaggattctt actttattct accaacagaa cttgaaaaat
      421 atttaccgaa taacaaagct attaatttat atctgtatta ctgttttaag gcaaagaatg
      481 aaggcgggga ttcctggcat tcggtcaata ccatagcaga gtctctagga gtgacaacta
      541 aaactataaa cacctggaat aaaaccttag ttgatttagg tatgattgca cgtatagacg
      601 ataaccatct cagtaaatcg acaattttac ttcctctctc tagttactat aaattagccc
      661 ttgatagttc tttaaaggat gttaccgaga gcactgtcca tgaaattgat ggcaacttgg
      721 ttgcagttta tcatttgttt gaatggagaa aaaatgaggc tgatgaaaat tataacgttc
      781 cttataacac actctgttgt gtttttaaaa gaaaaacaca aaaagatact atctataaat
      841 ttatcttggt ccaagatgag aaaataagta atttcgaatt aagcactcct tctagtaaga
      901 tttatgacga tgcatataga tttgaatgtc aagatctaga agccctcctt tccgcaaata
      961 atctaaacaa tatagaacat gaaaactttg ttgtaaacac tagatttaat ttagtttctg
     1021 aaaaggactc agatttgtta gatttgctga tagagcttac taaaaatcta gataagaaag
     1081 aaaacattac tgtactataa ctagcatcgg tccatcatta agtttggact attagaacac
     1141 ttgctattac agaaaaaggt atgctagcca cgcttactat ttattggtat caaacaagta
     1201 tcttaatttg aaaggaagat gatttatggc taatttatat atagagaaca a
//
LOCUS       DADLIO010000181         1246 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.191, whole genome shotgun sequence.
ACCESSION   DADLIO010000181 DADLIO010000000
VERSION     DADLIO010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.191"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            200..742
                     /locus_tag="JOX41_002917"
     CDS             200..742
                     /locus_tag="JOX41_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450590.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            832..>1246
                     /locus_tag="JOX41_002918"
     CDS             832..>1246
                     /locus_tag="JOX41_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HAY6450591.1"
                     /translation="MDELKRTEIQIIDKKERPKNGFVLSEKTDLENTEAFNKESVKDL
                     RKLPTKDINGKDFTSKDFEKYDLTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIV
                     GVVTDPVDDNGENKEAIEKSKLIHEKTKASYPFLMP"
BASE COUNT          514 a          141 c          238 g          353 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccag
//
LOCUS       DADLIO010000182         1235 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.192, whole genome shotgun sequence.
ACCESSION   DADLIO010000182 DADLIO010000000
VERSION     DADLIO010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1235)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1235)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1235
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.192"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            281..973
                     /locus_tag="JOX41_002919"
     CDS             281..973
                     /locus_tag="JOX41_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAY6450592.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT          527 a          167 c          200 g          341 t
ORIGIN      
        1 cgttttttgt aataaataca gtaatctatg aaatgaaaag ggttacgttt aataaaactt
       61 gcttttttgt ttttgttcac cataaatatt tatttaagaa agtattaacc tgcatttttc
      121 tctataaaaa agatttttta aatagataaa aaaggaggat taaatgagta tttgatagta
      181 tttatattaa aattacatat gtaatttaaa aacgcttgac attgtgtttg agatcactta
      241 cttttagcat gtaaaagtat tggattaagg agctatgcaa atgaaaaaga aatttattac
      301 tggtgggatt gtcgttgcat ttctatgtct aattggctac acaggcacgc ggtacgcaaa
      361 tgaaattatt ttgtggggtg gagagacaga tattgataca atcaatgaga atctgacaca
      421 gcttgatcat acattgacag ataaagagca agcgattaca gatcttaccg ctcgactagc
      481 acaaaaagaa cagacattgc aagattcaaa ggcagatgtc caagaatacc aaacaaaagt
      541 aaatgaatta gaaaaccaaa aaaatcaatc ggcagcagaa aaacaaaact tagaaagtca
      601 attagtcagc aaggatgcac aactacaaag caaacaaaat gaaatcaatg tcaaactaga
      661 tgagatcaac caaaaaaatg atgaaatcaa tcatctgaat gcagattgga cagcaagact
      721 acaagaagca caagcaaaac tttcagaatt acaaaatact gtaaatggtt tgaatcaaca
      781 aatcgcaaca ctgacacaag aaaaaacaaa tgtagaaact cagttaacag atacacaaaa
      841 gaaattagac gaagcaactg ctgaaaactc aagcttgaaa caatatattc aaaagttaga
      901 aaaagcaaaa gatgaagtgg aagatacagc tgataaatct cagcaaattg ttgaagaaca
      961 tttgcgtaaa taatctttct taacaagtaa acctaaatta gtaaagaagc aacagtaatc
     1021 tatactaagt agttcagttt tggagtacaa aatgacaaaa tgtacttcaa aatggactac
     1081 ttttttcatt ttaacttaca taccaaatta catacaaaat gatttataaa atgcaattga
     1141 aaatgataat tgaatgaaaa tttgtgattt tgtggtatta tgataatata acttatagaa
     1201 aaaattgctt attcaactaa cgggcaggat aatga
//
LOCUS       DADLIO010000183         1215 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.193, whole genome shotgun sequence.
ACCESSION   DADLIO010000183 DADLIO010000000
VERSION     DADLIO010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1215
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.193"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            <1..>1215
                     /locus_tag="JOX41_002920"
     rRNA            <1..>1215
                     /locus_tag="JOX41_002920"
                     /product="23S ribosomal RNA"
BASE COUNT          368 a          242 c          352 g          253 t
ORIGIN      
        1 ataagggcgc acggtggatg ccttggcact aggagccgat gaaggacggg actaacaccg
       61 atatgctttg gggagctgta cgtaagctat gatccagaga tttccgaatg ggggaaccca
      121 acatctttaa taggatgtta cgattgtgtg aatacatagc acattcgagg tagacgcaga
      181 gaactgaaac atctaagtac ctgcaggaag agaaagaaaa ttcgattccc tgagtagcgg
      241 cgagcgaaac gggaaaagcc caaaccagca agcttgcttg ttggggttgt aggactccaa
      301 tatggtagtt ctttcagata gtcgaatgac ttggaaaagt cagtcaaaga gggtaaaaac
      361 cccgtagacg aaatgtggaa gacacctagg aggatcctga gtacggcgga acacgagaaa
      421 ttccgtcgga atccgggagg accatctccc aaggctaaat actccctagt gaccgatagt
      481 gaaccagtac cgtgagggaa aggtgaaaag caccccggaa ggggagtgaa atagaacctg
      541 aaaccgtgtg cctacaacaa gtcaaagccc gttaatgggt gatggcgtgc cttttgtaga
      601 atgaaccggc gagttacgat tgcatgcgag gttaagttga agagacggag ccgcagcgaa
      661 agcgagtctg aatagggcgt ttgagtatgt agtcgtagac ccgaaaccat gtgatctacc
      721 catgtccagg ttgaaggtgc ggtaaaacgc actggaggac cgaacccacg tacgttgaaa
      781 agtgcgggga tgaggtgtgg gtagcggaga aattccaaac gaacttggag atagctggtt
      841 ctctccgaaa tagctttagg gctagcctcg gaattgagaa tgatggaggt agagcactgt
      901 ttggactagg ggcccatctc gggttaccga attcagataa actccgaatg ccattcattc
      961 atatccggga gtcagactgt gagtgataag atccatagtc gaaagggaaa cagcccagac
     1021 caccagctaa ggtcccaaaa tatatgttaa gtggaaaagg atgtggggtt gcacagacaa
     1081 ctaggatgtt ggcttagaag cagccaccat ttaaagagtg cgtaatagct cactagtcga
     1141 gtgaccctgc gccgaaaatg taccggggct aaacatatta ccgaagctgt ggagtacacc
     1201 tttaggtgta ttggt
//
LOCUS       DADLIO010000184         1215 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.194, whole genome shotgun sequence.
ACCESSION   DADLIO010000184 DADLIO010000000
VERSION     DADLIO010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1215
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.194"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            414..947
                     /locus_tag="JOX41_002921"
     CDS             414..947
                     /locus_tag="JOX41_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HAY6450593.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
BASE COUNT          389 a          226 c          225 g          375 t
ORIGIN      
        1 cttattaccg cagatgcaag cttttgaaca ccgtttattg agaagttgtg aaatcagcgt
       61 cctgacctga gtattagaga aacaaatggc aaaatagttc ctcatatttt gctatttttt
      121 gagctaatac cgagggtcag ctgattgaac accgtttagt ggagaagttg tgaaaaagtc
      181 gcctactttc gagtcgtaag aaattttttt gaaaatggtt cctcacaact ttgcataaat
      241 ttgacttaat accgagaagt catgatcccc atctaactcc aaatcacaag gaatgagttc
      301 aaaaactagc ttttctcaac aaatattaca taaaaaattc tatgtttttt gttaaattta
      361 tttgcttttt tcaaaagtat gttacagtaa tttcccaagg aggttttaca gaaatgaatt
      421 ttgttgccat ggattttgaa actgccaatc atcagcctta tagtgcttgt tctcttgcgc
      481 tagtcatggt aaaaaatagc cagatcgttg atgaattcta tacattgata cagcctgaga
      541 ctcctttttt ctggcgaaat gtccaaattc acggaatcca tcaagaagac gtacgcaatg
      601 cgccgaaatt cccagaagtc tggcaaacta tccaaccata ttttcaaaaa aatcgtttag
      661 tcgttgcaca taatgctgct tttgatacaa aggtcttagc gggatgctta gattattatc
      721 atcttgaaca gcctaattat ctttctttat gtacagtgaa aagtagccgt cgcctgtttc
      781 ctgaatttcc aaatcatcga ttgaacactg tgtgcgaaaa tttgaacatc caattagatc
      841 atcaccatga tgcattggaa gatagtcgtg catgtgcgga aatcctgctt tatcaagaaa
      901 aaaaattcgg gacagatcca ttgaaaaaac ttgtgactat aaagtaaaag aatacttatg
      961 aaacacacaa agaggtcgtg agcctgccgt ttcactccga gtcacaagga gcaatttcaa
     1021 aaaatagctt ctcatgttta ttaaatattg tgactggtga ccgaggagct ggcaggagaa
     1081 caccgtttat tggagaggtt gtgaaaaagc tgttctgcat caagtaataa gaacagccaa
     1141 acaaaaatag cttctcatat ttttcatttg gttggactta ttaccgcaga tgcaagcttt
     1201 tggacaccgt ttacc
//
LOCUS       DADLIO010000185         1214 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.195, whole genome shotgun sequence.
ACCESSION   DADLIO010000185 DADLIO010000000
VERSION     DADLIO010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1214)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1214)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1214
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.195"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            70..1026
                     /locus_tag="JOX41_002922"
     CDS             70..1026
                     /locus_tag="JOX41_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450594.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
     gene            complement(1080..>1214)
                     /locus_tag="JOX41_002923"
     CDS             complement(1080..>1214)
                     /locus_tag="JOX41_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAY6450595.1"
                     /translation="FNQVNQGFISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA
                     "
BASE COUNT          427 a          179 c          207 g          401 t
ORIGIN      
        1 ttgacaggga atcctaaaaa cattcggctt tttttatata atctttttaa ctcaacagag
       61 ataagttttg tggaattgta tacgctacct ataattataa aaacagaaaa aatgttaaaa
      121 gatttaaaac agtattatcc tctgtctgct tatgaaaaaa agaaattatt ccacttttta
      181 gcaatcaacc tgttggctga acaagctgat tctttagata ttgctagcaa tcagtcgcta
      241 tttttttcgg atataggatt ttaccactta aaaggagtat taggagaaaa atccgttatt
      301 tttatcaata agacactctc ttggctttat cttcatgata aattggatca aaaatacttg
      361 agaaaaaatg aagatgaaac aatcgaatgg ttgaatgaac gattcattga aagttttgaa
      421 aatcagttta atctgttgcg agaagagacg agccaattga tccgaagaga gttaaccaaa
      481 atacatttta aacttttgca ttacactatt aataaagctg atgaatttcc acttgatgtt
      541 tcttttttta gagaaaacta tccagcattt tattgctatt tgatagagta tataaatgat
      601 ctaacgtcaa aacgcaaaga gttgcttcaa gataaatttt ttcttttttt cagttattta
      661 ttattattga tcaatcacat acccattcaa ctgatttctg aaccagtaaa gatcatcatc
      721 gatttttctt atggtgctgc ctataatcaa tttatcaaga aaaatttaag cttgtacatt
      781 aatctgaaca cggaagtgat agaggcagga aagcctgagt tcccggatgt tataatcacg
      841 aataggaata atctatatga agaaagtgca tctcaagtag tggtttggct cgatccgcca
      901 agagcagtag actgggggaa tcttacaaag attttgttga ctatccaaga agagaaatac
      961 aaagacagca aaattgacaa gcaaatagac gattttcctg aagaaatcat cgacaggatc
     1021 gaatagtgaa cttcttttag aaagtccgac tgctttttct aaaaatatta tttgtcaaat
     1081 taagcgagac aaaactttcc atttacgtaa ctcaaaaaaa cttctaatgg tgtttggtaa
     1141 tttagtgatt ttctagggat atggtttctt ttggacgcaa cggatgagat gaatccttga
     1201 ttgacttggt tgaa
//
LOCUS       DADLIO010000186         1193 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.196, whole genome shotgun sequence.
ACCESSION   DADLIO010000186 DADLIO010000000
VERSION     DADLIO010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1193
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.196"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            <1..1076
                     /locus_tag="JOX41_002924"
     CDS             <1..1076
                     /locus_tag="JOX41_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAY6450596.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          210 g          331 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tct
//
LOCUS       DADLIO010000187         1128 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.198, whole genome shotgun sequence.
ACCESSION   DADLIO010000187 DADLIO010000000
VERSION     DADLIO010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1128
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.198"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            4..963
                     /locus_tag="JOX41_002925"
     CDS             4..963
                     /locus_tag="JOX41_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAY6450597.1"
                     /translation="MNGFAYTINNEFNLGANEGSSQVANNQYILLHETANETATGRNE
                     AQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGSYANANSPVQIELQHTHDKAT
                     FEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHLWVTQNIWGDHTDPYGYLSEM
                     GVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNYAHIDQFGEIEN
                     ANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRSDVNQAYNTSGNVGYHVSF
                     NMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
BASE COUNT          383 a          209 c          224 g          312 t
ORIGIN      
        1 ccaattaacg gatttgccta tactatcaac aatgaattta atttgggcgc aaatgaaggt
       61 agctcacaag tagcaaataa tcagtatatt ttactgcatg aaacggctaa tgaaacagca
      121 acaggacgca atgaagcgca gtatatgcaa cgttcatgga ctagcgctta tactgcttat
      181 attgtgggag acggcggaat tgtttatcaa gtcggtcaac ctggttatgt acagtacggt
      241 gctggttcgt atgctaatgc caacagtcct gtgcagattg agttacaaca cacacatgat
      301 aaagcaacgt ttgagaaaaa ctacaaggca tacgttgaat tggctagaga ttcagcaatg
      361 aaatatggta ttccattaac gttggacact ccttataacc aaccgggaat caaatcgcat
      421 ttatgggtaa cacaaaacat ctggggcgat catacagatc cttacggtta tctttctgaa
      481 atgggcgtaa gtaaagaaaa attagcatat gatttagctc atggatttac cgatgaaaat
      541 ccaacaactt ctgaaaacaa gcctgtcatt gatccaacac gagctggtgc agctaatcct
      601 acactgacag atggaacgaa ttacgcccac attgatcagt ttggagaaat cgaaaatgca
      661 aatttgcatg tagctggatg gcacattgct aactataaat acgagtatat cttcattatg
      721 gattacaata ctgggaaaga attagctcga gtaagagctg atggaattta tagatcagat
      781 gtaaatcaag cttataatac ttctggaaat gttggctatc atgtatcttt taacatgcgt
      841 aacttcccta ataagaaagt ctatgtcatg atgcgggcaa cgaatgatcc agagggaaac
      901 actaaaggcg gtgcgcaaga tttccatgac aaacgttggt atttaaatat tcctaaacga
      961 taaaaatagc tcctcgttga ggagcattac ataactatat tgacaactat aaaaatcatt
     1021 cgataaaata gtgatgttat cgcatatctt cactatcacc cataatagtc acactccaag
     1081 ctatgcgata acaggtttgt tgccacacat tctactggtt gattgttt
//
LOCUS       DADLIO010000188         1117 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.199, whole genome shotgun sequence.
ACCESSION   DADLIO010000188 DADLIO010000000
VERSION     DADLIO010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1117)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1117)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1117
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.199"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(167..240)
                     /locus_tag="JOX41_002926"
     tRNA            complement(167..240)
                     /locus_tag="JOX41_002926"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(204..206),aa:Ile,seq:cat)
     gene            complement(795..1109)
                     /locus_tag="JOX41_002927"
     CDS             complement(795..1109)
                     /locus_tag="JOX41_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450598.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT          420 a          176 c          170 g          351 t
ORIGIN      
        1 aacttttcaa atatacagaa gtataactat gtgaaacatc ctttcattaa tccataaaag
       61 gatacataaa aaagccactc atttgagtgg caatgaagaa aagctttagc ttgtataata
      121 ctcttcaaaa aattctaaca cagaacgatt caattggcta cattaatgta ccctgtagga
      181 ctcgaaccta cgaccggacg gttatgagcc gtctgctctg accaactgag ctaagggtag
      241 tggttgttgc cacataaagc cataaacaat caaccagtag aatgcgtggc aacaaacctg
      301 ttatcgcata tcttggagtg tgactattta tgagtgatag tgaagatatg cgtctccata
      361 tatgtatggt tgagacagat aaacatgtat gaaaaacgtt gttaaatcaa cgttttttta
      421 ttttggtcaa ggagagaaaa gtagagaaat acaaaatttt ttgcattgat tttgcattca
      481 aaaaaacatt caaacattta gaaatcccca atacgtattc aggaaaatct attttaaggt
      541 ttacaaaaag aacttttgtt cgtacactct ttttgaggtg aacttttatg ctgatggaag
      601 gaaaaacaca attatggttt aagcatgttc cttcaaataa gttttttaat tataaactct
      661 agagaaatta attcatccta acataaaata attgttcact caaaagtttt tctagaacaa
      721 ttaaaacagc aggcttcaca ttcgctatac atttgtaaga agtaataatt cctgtactaa
      781 aaggcataat tgctttaatt attttttgac ttctcttcaa acacaagaag tagttgtgta
      841 ataattgcag aaataaggat tccaataata gatataaaat ttgacatgga aacgtctata
      901 acattaaaag aataaagtgt tgaagaaagt aaactgattg aaataacccc tccgtaaaaa
      961 atagtctgtg aatataccca ctttttttca gaagacgtac ttcgtttggt tctaaaacct
     1021 atccctgcat ttctactctt atcaaaaaac caaatattta gaagtaataa tattgctatt
     1081 attaagataa aattactgta aaaatccaaa agctatc
//
LOCUS       DADLIO010000189         1069 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.200, whole genome shotgun sequence.
ACCESSION   DADLIO010000189 DADLIO010000000
VERSION     DADLIO010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1069
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.200"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            <1..969
                     /locus_tag="JOX41_002928"
     CDS             <1..969
                     /locus_tag="JOX41_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAY6450599.1"
                     /translation="PINTFAYTINDEYNLAPNQGDSRLAIPNKIILHETGIDAPARNV
                     AANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAGNANPYAPVQIELQRTYDKA
                     LFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIISHLWVTNYVWGNHTDPYGYL
                     SQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNHAHIDQFGE
                     IENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRPDVNQAYNTSGNVGYH
                     VSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
BASE COUNT          368 a          185 c          214 g          302 t
ORIGIN      
        1 cccattaata cgtttgctta tactattaat gacgagtata atttagcgcc gaatcaagga
       61 gactccagat tagcaattcc taacaaaatt attttgcacg aaactggaat agatgcacca
      121 gcaagaaacg tagccgccaa catgaaaaat aattataacg gaagcaattc ttatactaca
      181 gatgttattg gtgacggtgg gattgtttac cgtgtgggtg agcaaggata tgtttcgtgg
      241 ggagctggta acgctaatcc ttatgcgcct gtacagattg aattacagcg cacatatgat
      301 aaagcattgt ttgaaaaaaa ctatcgagct tatattgaat atacaagaga tagtgcaaaa
      361 aaatatggaa ttccattgac tcttgatcaa ggaacttctt tatttacaaa aggaatcatt
      421 tctcatttgt gggtgacaaa ttatgtttgg gggaaccaca cagatccata tggttactta
      481 tcgcaaatgg gagttagcaa agaaaagctt gcttatgatt tagctcatgg atttaccgat
      541 gaaaatccaa caacttctga aaacaagcct gtcattgatc caacacgagc tggtgcagct
      601 aatcctacgc tgacagatgg aacaaatcac gcccacattg atcagtttgg ggaaatcgaa
      661 aacgcaaact tgcatgtggc tggatggcac attgctaact ataaatacga gtatattttc
      721 attatggact acaatactgg gaaagaatta gctcgagtaa gagctgatgg aatttataga
      781 ccagatgtaa accaagctta taatacttct ggaaatgttg gttatcatgt atctttcaat
      841 atgcgtaatt ttcctagtaa gaaagtctat gtaatgatgc gggcaacgaa tgatccagag
      901 ggaaacacta aaggcggtgc gcaagatttc catgacaaac gttggtattt aaatattcct
      961 aaacgataaa aatagctcct cgttgaggag cagtacataa ctatattgac aactataaaa
     1021 attattcgat aaaatagtga tgttatcgca tatcttcact atcacccat
//
LOCUS       DADLIO010000190         1014 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.201, whole genome shotgun sequence.
ACCESSION   DADLIO010000190 DADLIO010000000
VERSION     DADLIO010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1014
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.201"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            <1..354
                     /locus_tag="JOX41_002929"
     CDS             <1..354
                     /locus_tag="JOX41_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAY6450600.1"
                     /translation="TQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVD
                     QEMYKQAQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISI
                     LKELEEHENWYAEVE"
     gene            355..903
                     /locus_tag="JOX41_002930"
     CDS             355..903
                     /locus_tag="JOX41_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450601.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
BASE COUNT          400 a          139 c          214 g          261 t
ORIGIN      
        1 acccaagtaa aatcgatgag aaatgcgatg caatatcttg agtatatgga cttttttgtg
       61 aaagaatttg atacaaattt atatgttgct ggtgttattc ctttcatgtt ggaaagcggt
      121 gacgcagtag atcaggaaat gtataaacaa gcccaagaga tttatgggga acatttgatt
      181 aaaaatgttg tactcaaaaa tgcgcgctta aaacgatacg acggatcagg tattacgatg
      241 gagaagacaa agaaaggtct cttaaaacaa tgggatcgca aaagccacga attatttatc
      301 agtattttga aagaattgga agaacacgag aattggtatg cggaggtgga gtaattggct
      361 gacatcaaag gacttgatat ttttgggaac aacaaaggac tcgccaaaat aaaaaaagaa
      421 gcagaagcaa agaaaaagca gcaagcaatt acaccatctg aaaataagca attagaagtg
      481 caccaagttc aagaaataaa aacttcctcc aatgttgaaa gacagagtag aggaagaaca
      541 aaaaaagttg gcgcaccaat cagaaagttt gataaggttt attccaccaa gcatccttta
      601 aaactgtcga ctttgttaaa tgcgacttcc agagttttag tagaaaagta tgagactaat
      661 atgacaagag atgaattgct tagaaaagct ttagatgagt atattaaaca gaatcttacg
      721 caagaagata agcaagattt gtttaatgac gtggtgaaag aactagactt gttcagagaa
      781 aaatatccaa ttgttccaga attagatgat cgtggagaaa taataagaac taccagtcag
      841 ataaaacaag ataccgaaga ctcactgcgc aaagggtggg gaatgaataa taaagttaga
      901 taataatcaa agaagaacta agtaactacc tttaaacggt agttacttag ttcttctttg
      961 atttgcatga aatagagggg atttattttt ctggttacgt gattaaaaaa tcca
//
LOCUS       DADLIO010000191         1007 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.202, whole genome shotgun sequence.
ACCESSION   DADLIO010000191 DADLIO010000000
VERSION     DADLIO010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1007
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.202"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            <1..708
                     /locus_tag="JOX41_002931"
     CDS             <1..708
                     /locus_tag="JOX41_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450602.1"
                     /translation="FTGEEEIVMNTRNTPTQHLATSIHELAHARMHKFSELDTATKEL
                     QAEMTSYIVCKHFGMDTSEKAIPYIAAWTKNGQTLDDKEAAERGKIMNDVSRVANEFI
                     QTISNEINQYREREPEIQPAEVKQEHKNTVETAENKNIVPVGSLWIDKKDGKVMEEDT
                     GRTLHLKDAAFIEDPQHNQVILKGKSYGKEIQTALPSEEFALGNPFRFSLETVSEVAK
                     RKNEIYYEQQLSQKERV"
     gene            769..>1007
                     /locus_tag="JOX41_002932"
     CDS             769..>1007
                     /locus_tag="JOX41_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450603.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDS"
BASE COUNT          380 a          156 c          216 g          255 t
ORIGIN      
        1 tttactggcg aagaagaaat cgtcatgaat actcgaaata ctcctacgca gcatttagct
       61 acaagtattc atgaattagc ccatgcaaga atgcacaaat tttcagaatt agataccgca
      121 actaaagaat tgcaggcaga aatgacttct tatattgtgt gcaaacattt tggaatggac
      181 acttcggaga aagctattcc ttatattgca gcatggacga agaatggtca gacgttggat
      241 gataaggaag cggcggaacg tgggaaaatc atgaatgatg tcagccgtgt cgcaaatgaa
      301 ttcattcaaa ccatttctaa tgaaatcaat caatacagag aaagagaacc agagatccaa
      361 ccagcagaag tgaagcagga gcataaaaat actgtagaaa cggcagagaa taagaatatt
      421 gtgcccgttg gttcactttg gatcgacaag aaagacggga aagtaatgga agaagatacg
      481 ggtcgaacgt tacatttgaa ggatgcggcg tttattgaag atccgcagca taatcaagtg
      541 attttaaaag gaaaaagtta tggaaaagag attcaaacgg cgttaccttc agaagaattt
      601 gcgctaggaa atccattccg attttcactt gaaacagtgt cagaagtggc caaacgaaaa
      661 aatgaaatct attatgaaca acaattgtca caaaaagaac gcgtataaaa caagtaaaaa
      721 agactatctg aaaaacggat agtctttttt cttttgggag gtttgaaaat gaccgaaaaa
      781 aaaatgagtc ttattgatcg atgtaaacag atcgatatag tggattttgc tcgaaacaat
      841 ggaatggctg tagtcaataa aggacgagac tatcgcttag aagaccatga ttcatttgtt
      901 tttgatcgaa gaaaacaacg tttttattgg aacagtcaaa atattagtgg cgacattatt
      961 gaattagcta aacttttttt catagacaaa gagatccaag actctaa
//
LOCUS       DADLIO010000192         1003 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.203, whole genome shotgun sequence.
ACCESSION   DADLIO010000192 DADLIO010000000
VERSION     DADLIO010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1003
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.203"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            370..1003
                     /locus_tag="JOX41_002933"
                     /pseudo
     CDS             370..1003
                     /locus_tag="JOX41_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          342 a          182 c          184 g          295 t
ORIGIN      
        1 gtttcaaagt tagtagagaa aatgtagtta tatatttaaa tttttaccag aaagaaatga
       61 acaccttcaa ttatctaaat ctcgaaaatg gttagatgta atcatcagga aaaacaatct
      121 taaacgaatt actattcatg gtcttagaca cacacatgct agcttgcttt tagcaagcta
      181 gtgcaaatat taaagatgtg caagagcgtt taggccactc ttctattcaa atcattatgg
      241 atctatatat tcatattaca gacaaaagaa aagaagaaac cgtagcgcaa ttcgcaaaat
      301 ataggctcta taatttatgg gactgatgaa tcaaaattga ttcttcagtc ccattgttat
      361 tttaggtata tgattcgtac attgaaagag ttgaaaaact atcttccgaa gccgtcaaaa
      421 aggaccctgc caaaagtatt gatggtggat gaatttcgtt cgcacgcttc aattgtggat
      481 aaaatgagct ttatttgtgc ggatggcgag actggaaaac tcattgatat tttgcctaca
      541 cgaaaattgt ctcgattaac acactatttt agtcgctgtg caaatcctga agcggtggaa
      601 tatttagtga cagatatgaa cgccgcctac ttccaactga caaaacgtgt cttaccaaat
      661 gcgaaagtcg tcattgattg ttttcatatc atcaaacatt tgaatcaggc gttcaatgat
      721 tttcgtgtac aagaaatgaa aagattacac cagttagggc aacgacggga agccgagaaa
      781 gtgaaaaaga actggcgctt tcttctaaaa aaccgtcaaa aaatcaatca ctatgattac
      841 aaaacatggc gcagttttcg tgcacctaaa tacccgctac tcactgaagc aatgatgatt
      901 gatcgattgc tggcattttc aacgccttta aaggacgcct atactttttt ccatgagctg
      961 accgaagcct ttagagacaa ggaatcagac ttatttttta cct
//
LOCUS       DADLIO010000193          961 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.204, whole genome shotgun sequence.
ACCESSION   DADLIO010000193 DADLIO010000000
VERSION     DADLIO010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..961
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.204"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            172..459
                     /locus_tag="JOX41_002934"
                     /pseudo
     CDS             172..459
                     /locus_tag="JOX41_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            473..904
                     /locus_tag="JOX41_002935"
     CDS             473..904
                     /locus_tag="JOX41_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450604.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
BASE COUNT          362 a          140 c          203 g          256 t
ORIGIN      
        1 gctaaatact taaaaacgca tgtagaagct attgatggta aagaagcatt ggtgcagaca
       61 gatggagacc aagccattgc aggacataag aatttttcag gttctgtaac aatcaataat
      121 aaacgtgttt tgacgactga tgataacaga tatgaagtgg taaatctggt tgtcactaac
      181 ggtaatacag ggacagcaaa gctttatcgt gaaggaaaaa cagtttctat atattttgtg
      241 gctttaaacg gaaaaagtag tggcgggaat gattcggtta ttttaactgt tccagaaggc
      301 tatcggacac caattagttt tgaacaactg gttgggtcaa tagaccgttc tactttgaac
      361 agtgctcaac tatctattgg cgcagacgga gccattaaat ggagaagaaa ttcaagttat
      421 ggatcagctt attcatttgt tatcacttat tcaatttaag ggaggaaatc taatgaaagt
      481 agtttacaaa tcaatcaagc cttacggatt cgagcaaatc attttgaaca atcaagaaaa
      541 tatccctgaa aactgtacag agattaaacc accagttcct aactggagac caagatttga
      601 ttttgataaa aaacagtggg ttgagttagc tactgaagaa gagaaaaaag ggaatgctgt
      661 tgatagcgta gatgaattgg ctaatattaa ggcattatac gaaacgctga aggcagaaaa
      721 tgatgaattg aaacagctaa attctaaagc aatgctaaac aatgtagcaa tcaagcaaga
      781 aaatgtctta ttgaaagaaa agtcagaaag tttagcgcag ttgaattcaa aaacgatgct
      841 tgcttctgta caaaatacca aggaaatcga agaaatcaaa aaacaattac aaggtgggaa
      901 gtaacatgta ttcatatgaa gatatcaaac taatgtatga ctggggctgt ttcactaacg
      961 a
//
LOCUS       DADLIO010000194          921 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.205, whole genome shotgun sequence.
ACCESSION   DADLIO010000194 DADLIO010000000
VERSION     DADLIO010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 921)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 921)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..921
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.205"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            682..>921
                     /locus_tag="JOX41_002936"
     CDS             682..>921
                     /locus_tag="JOX41_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450605.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNASIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSIS"
BASE COUNT          310 a          118 c          126 g          367 t
ORIGIN      
        1 aaagatattt tcaaaacatt ttttcttgat gtgatatcct tgtctttttt gtaatgtttt
       61 taacttattg cttttgcaaa atttatttac ctgttttctg gatcaacgat agtgtatatt
      121 atgctatcct tgtttggatt ttaggacgtt taaagaggca cttttttaca taacttaatc
      181 catagacctt ttaagcatgc tgtgagataa taataaagaa gagtttaaag cgcaccccaa
      241 accacttccc cataagtgta ttacgcttta aactctttta tatttgaatt cactaagaag
      301 cataccatat ttttgaaaaa aagtgagaaa aaaggcttat aattaggatt tagagtaatt
      361 aattagatgt ttattttata ggactgatat tatagattac aaatagtatc gtatttcgca
      421 atcttaaaat tatcttctta ctatgaataa gataataaaa tttgtatttg tcctttttag
      481 gtaacttatt ttaatctata tacctttctg gatcaacgaa agtatacttt atatagtcat
      541 aacgccgatg gtaactatgc actgtaacga taatgctgct aaaatatctt tttacgaaaa
      601 acatcacaag gaaaaactta actatggtat tatctaaaca taattttttc ggtatttaat
      661 atttaattag gagggaatat tttgcttttt tatagtaatt ttatcttaat agtagcgata
      721 ttattacttc tgaatatatg gatttttgat aggagtagaa atgcaagtat aggttttaga
      781 actaaacgaa gtctgtcttc taaaaaaaat tgggtatact cacaaactat tttttatgga
      841 ggaattgttt taattagttt actttcttca acactttatt ctttgaatat tatagatgtt
      901 tccacctcaa attcaatatc t
//
LOCUS       DADLIO010000195          914 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.206, whole genome shotgun sequence.
ACCESSION   DADLIO010000195 DADLIO010000000
VERSION     DADLIO010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..914
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.206"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            132..>914
                     /locus_tag="JOX41_002937"
     CDS             132..>914
                     /locus_tag="JOX41_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HAY6450606.1"
                     /translation="MNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAFHINR
                     ALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLYIVTL
                     ITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPLILLG
                     FIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIFLIIK
                     LIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYL"
BASE COUNT          312 a          117 c          121 g          364 t
ORIGIN      
        1 aaacactact tttgtaatat aaaaaatatt ttattaataa taaaattaat cacattttat
       61 atagtgacta atctagtgtt taaaaaaaat aaatgatact atatgtaata taaaaaaaca
      121 tgaggtggta tatgaatttg aaaaaaattt tttctgtaaa aatatttata gtttatgcat
      181 ttgttagttt attatattta tttccagcat ttaaaaacat ggaaatattt ggcttttatg
      241 atacggcatt tcacattaat cgtgcgttaa gtttagaatc tatttttagc tcccctatta
      301 attttgaaac gtttagatca tatggcatgc aagtaaataa tttttaccca tggttaactc
      361 tatatccttt atttttattg atcaagttta ctaatttagc aataggctat aacctttttc
      421 tttatattgt tacgctcatt actctattta tatgtcatta tgtaatgtat gaaattacca
      481 aaaaacatgt tactagctcc tttttcgcta ttatatatac aacatcttct tttaggagtg
      541 tagaaatatt tcttcgaggg gcaatggggg aattactcgc aatgtcaata cttcctctta
      601 ttttactcgg gtttataaag ctttacgact caaaaaaaga atcttgggtt atgttggcga
      661 ttagcatgac tttattaatt tacactcatg ttctttctgt agctatgact atggtaatga
      721 ttataattgc tttaattatt caattttatc ggaaaaagaa aatagaaatc ttcttaatta
      781 ttaaattaat aaaagctgct atagttactt tacttctttc actagcgttt ataggtccta
      841 tgattgagca gacattgtat caagatctga atagacctta tgtggatata ttacaaaaaa
      901 gagcaattta tctg
//
LOCUS       DADLIO010000196          896 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.207, whole genome shotgun sequence.
ACCESSION   DADLIO010000196 DADLIO010000000
VERSION     DADLIO010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 896)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 896)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..896
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.207"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            4..>896
                     /locus_tag="JOX41_002938"
     CDS             4..>896
                     /locus_tag="JOX41_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase family protein"
                     /protein_id="HAY6450607.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAI"
BASE COUNT          303 a          122 c          164 g          307 t
ORIGIN      
        1 actatgtgta cgtctattac ttatgtaaca agtgatcatt attttggaag gaattttgat
       61 tatgaaatat cttacaatga agtagtcact gttactccaa gaaattataa gttgaatttt
      121 cgaaaggtaa atgatttgga tactcattat gcaatgattg gtattgccgc tggtatagct
      181 gactaccctc tttattacga tgcgacaaat gaaaaaggat tgagtatggc tgggctaaat
      241 ttttctgggt atgctgatta taaagaaata caagaaggga aagacaatgt atctcctttt
      301 gaatttattc cttggatttt aggacaatgc tcaacagtag gagaagctaa aaaattgtta
      361 aaaaatatca atttagcaaa tataaattat agtgatgaac ttcctttatc ccctttacat
      421 tggctattag ctgataaaga aaaatcaatt gtcattgaaa gtatgaaaga tggacttcat
      481 atatatgata accctgtggg cgttcttacc aataatcctt catttgacta tcaattattt
      541 aatttaaaca attatcgtgt cttatcgagt gaaactccta aaaataattt ttcaaatcaa
      601 ataagtttga atgcctatag ccgcggtatg ggagggatag gcttgcctgg agatttatcc
      661 tcagtatctc gttttgttaa agcgactttt acgaagctga attctgtatc tggagattca
      721 gagtcagaaa gtattagtca atttttccat atcttaggtt cagtagaaca acaaaaaggt
      781 ttgtgtgatg ttggtgatgg aaaatatgaa tatacaattt attcttcttg ttgcaatgtt
      841 gacaaaggaa tctattatta tcgaacatat gaagacagtc aaattactgc aattga
//
LOCUS       DADLIO010000197          893 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.208, whole genome shotgun sequence.
ACCESSION   DADLIO010000197 DADLIO010000000
VERSION     DADLIO010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..893
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.208"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            252..875
                     /locus_tag="JOX41_002939"
     CDS             252..875
                     /locus_tag="JOX41_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAY6450608.1"
                     /translation="MYLAYLRVSSDDQSLARQHKLIENWSVKNNIAEDDLKIFEEKVS
                     GKNIENRPELQELISFIRERDTIIIPSLDRLARNSKDTKDLLQLFRSKGASIEILDLP
                     SFNGVTDPALRDLLTNLVIEVFSYVAENERKKIKERQKQGIEIAKKNGRYTGKKIQYH
                     ANATGKNKLIYDEIVDGLKKKETISKIAKNAGVTRKTVYRVKRDLGM"
BASE COUNT          328 a          129 c          167 g          269 t
ORIGIN      
        1 aactaatgtc cttatttttg tgttcacatt tctgttacct aagaaatact taaaggaggt
       61 gatgtagcca gcaacgacta caacttgaac ccgctatcta cagtttattt gttgtttctt
      121 ttgggtatac tctaatggta caaatccata tttgcttaaa gcgttgattt ttcagcggtt
      181 tttctttatt gcaaagtgta ccctaagacc tgtatactaa tagtaaatag attggatagg
      241 aatgatggca aatgtattta gcttatttaa gagtttcttc cgacgatcaa agtttagctc
      301 ggcaacataa gctaattgaa aattggtcag tcaaaaataa tattgctgaa gacgatttaa
      361 aaattttcga ggaaaaagtc tctggaaaaa atattgaaaa cagaccagag ctgcaagagc
      421 ttatttcttt catacgtgaa cgagatacga ttattattcc tagtcttgat cgattagcaa
      481 gaaatagtaa agatacaaaa gacttacttc aattgtttcg tagtaaaggt gcttctattg
      541 aaatattaga cctaccgtcg tttaatgggg taactgaccc tgcattaaga gacttgctaa
      601 caaatttagt catagaagtg tttagctatg ttgctgaaaa cgaacggaaa aaaatcaaag
      661 agcgtcaaaa acaaggcatt gaaattgcaa agaaaaatgg tcgttatact ggtaaaaaga
      721 ttcaatacca tgccaatgca acaggaaaaa acaaattgat ttacgatgaa attgttgatg
      781 gtctgaagaa aaaagaaact atttctaaaa tagcaaagaa cgcaggagtt acaagaaaaa
      841 ccgtttatcg agtaaaaaga gatttaggaa tgtaatatgt tccagttaga aag
//
LOCUS       DADLIO010000198          803 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.209, whole genome shotgun sequence.
ACCESSION   DADLIO010000198 DADLIO010000000
VERSION     DADLIO010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..803
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.209"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            <1..672
                     /gene="tnpB"
                     /locus_tag="JOX41_002940"
     CDS             <1..672
                     /gene="tnpB"
                     /locus_tag="JOX41_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element transposase accessory
                     protein TnpB"
                     /protein_id="HAY6450609.1"
                     /translation="SGKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDN
                     NKFTSKMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTD
                     FLNKLSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRK
                     IIKVDKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLH
                     SMGLA"
BASE COUNT          296 a          125 c          150 g          232 t
ORIGIN      
        1 agcggtaaat actatatttc tttgttgtgt aaagaagaaa ttatcgaatt acctaaaact
       61 aattccacaa ttggtattga cttaggtatt atggactttg cgattctttc tgatggacaa
      121 aaaattgata ataataaatt cacgtccaaa atggaaaaga aactaaagcg tgaacaacgc
      181 aaattgtcta ggcgtgcttt attggctaaa aataaaggta ccaatctatt tgaagctaaa
      241 aattatcaaa aacaaaaacg caaagtagct agattgcatg aaaaagtaat gaatcaacgt
      301 actgattttc tgaataagtt gagtacagaa atgatcaaaa atcacgatat tatctgtatt
      361 gaagacttaa acacaaaagg tatgttgcga aatcataaat tagctaaaag tatttctgat
      421 gtttcttggt caaagtttgt gactaaatta caatacaagg ctgactggta tggacgaaaa
      481 atcatcaaag tagataaatg gtttccgtct agtcagattt gttcagagtg cggacataaa
      541 gatggcaaga aatctcttga aattcgagaa tggacttgtc ctgtttgtca tactcatcat
      601 gatcgtgata tcaatgctag tatcaatatt ctgaccgaag gtctaagact acattctatg
      661 ggattggctt agatccaatc atcaagaacc gtaggaacta cggggatagc ttggtaaata
      721 agagacaccg ctgttagtaa agaaatacgc tatcaagtat gctctattcc caagaagctc
      781 ccacttcaag cgttaagaac cgt
//
LOCUS       DADLIO010000199          792 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.210, whole genome shotgun sequence.
ACCESSION   DADLIO010000199 DADLIO010000000
VERSION     DADLIO010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 792)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 792)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..792
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.210"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            10..>792
                     /locus_tag="JOX41_002941"
     CDS             10..>792
                     /locus_tag="JOX41_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAY6450610.1"
                     /translation="MNRSRQTIHKVYLFFKQGKSALEYYQQYKKNKSNCGRRPLVLPE
                     EQSEYIQRKVVQGWTPDVIVGRAAFPISCSARTIYRMFKKGLFDSSDLPMKGKRKPNG
                     HQERRGKQTFRRSIHEREKDYSQFSNEFGHLEGDTIVGLKHKSAVITLVERLSKVIIT
                     LKPCGRQAIDIEKKLNQWFESVPKNLFKSITFDCGKEFSNWKQISNVNDIAIYFADPG
                     TPSQRGLNENSNGLLRRDGLLKSMDFNSVDEFFIQSVASKRNN"
BASE COUNT          269 a          137 c          153 g          233 t
ORIGIN      
        1 gcccattgct tgaatcgttc aagacaaacg atccataaag tatatctgtt cttcaagcaa
       61 ggaaaatcag ccttagaata ttatcaacag tataagaaaa acaaatcaaa ctgtggtaga
      121 cgtccgcttg ttttacccga ggaacaatca gaatatattc aaagaaaggt tgttcaagga
      181 tggacacccg atgtgattgt tggtcgtgca gcgtttccta ttagttgttc tgctcgtacc
      241 atttatcgta tgttcaaaaa ggggctattt gattcttctg acttaccgat gaaaggcaag
      301 cgtaaaccga atggacatca agaaagacgt ggaaaacaaa ctttccgccg ctctattcat
      361 gaacgtgaaa aggattatag ccaattctca aatgagtttg gtcaccttga aggtgacact
      421 atcgtaggtc tgaaacataa aagtgctgta attaccttag ttgaacgatt atcaaaagtt
      481 atcatcacat tgaaaccgtg tggtagacaa gcgattgata ttgaaaaaaa attaaatcaa
      541 tggtttgaat ctgtaccgaa aaacctattc aaatccatca cttttgattg tggaaaggaa
      601 ttttcaaatt ggaaacagat cagtaatgtc aatgatattg ccatttattt cgctgatcca
      661 ggaacgccgt ctcaaagagg cctaaacgag aattctaacg gattgttacg tagagatggt
      721 ttattgaaat ctatggattt caattcagta gatgaatttt ttattcaatc tgtcgcatct
      781 aaacgaaata at
//
LOCUS       DADLIO010000200          791 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.211, whole genome shotgun sequence.
ACCESSION   DADLIO010000200 DADLIO010000000
VERSION     DADLIO010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.211"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            7..624
                     /locus_tag="JOX41_002942"
     CDS             7..624
                     /locus_tag="JOX41_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450611.1"
                     /translation="MGFQVLFGSLILTIVFLKWKTSNKKSMWSLVGIVLIIFTVTAAT
                     EANYSHKIQSYKGRLVMTKKDVTRYTSSRTGGLYDYAPLDALKYKDHLKKHEVKVGDR
                     WENASHKAYNSKIVYTVEDADEQNITLPVFNYWGTVVKVNGKKSTIENDNGLVSIKGT
                     GKRTIVEVSSTYPTTMILSLLISSITFIFLFTRYLIRCCGEMKID"
BASE COUNT          308 a           97 c          146 g          240 t
ORIGIN      
        1 agaaccttgg gttttcaagt gctttttggt tcattaatct taaccatagt gtttttaaag
       61 tggaaaacaa gcaacaaaaa aagtatgtgg agccttgtag gaatagttct tattattttt
      121 actgtgactg cagcaacaga agcaaattat tcgcataaaa ttcagtcgta taaaggtcgt
      181 ttagttatga ccaaaaaaga tgttacacgt tatacatcct caagaactgg aggcctatat
      241 gactatgcac cattagatgc attgaaatat aaagatcatt taaagaaaca tgaagtaaaa
      301 gttggtgatc ggtgggagaa tgcatctcat aaagcatata attccaaaat agtctataca
      361 gtagaagatg ccgatgagca aaatatcaca ttacctgtat tcaattattg gggaacagtt
      421 gtgaaagtaa atgggaaaaa gagcactata gaaaatgaca atggtttagt gtctattaaa
      481 ggtacgggga aaagaactat agttgaggtt tcatctacgt atccaactac gatgattcta
      541 tctttattaa ttagttcaat aacttttata ttcttattta cacgttattt aataagatgc
      601 tgcggtgaaa tgaaaataga ttagatagat attataaata tgttgattct attttcatag
      661 caatggagaa aatacattag caatatataa aagaaggtat caagagtcac agtgaattta
      721 ttccgaaaag tgaaaagagc aaatataaaa tttaatgaaa atatagaact aaataggaaa
      781 acgtagacgt a
//
LOCUS       DADLIO010000201          736 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.212, whole genome shotgun sequence.
ACCESSION   DADLIO010000201 DADLIO010000000
VERSION     DADLIO010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..736
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.212"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            <1..734
                     /locus_tag="JOX41_002943"
     CDS             <1..734
                     /locus_tag="JOX41_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HAY6450612.1"
                     /translation="DKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRK
                     LMSQMGLTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKI
                     YLSPILDLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQ
                     YQKKLKENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIR
                     WYNNKRIKLKLNGLSPVEYRKQSIK"
BASE COUNT          318 a           94 c          122 g          202 t
ORIGIN      
        1 cagataaata tagcaagata aagcaagaaa ttacagcgat tgtaaaagaa tcaagaaact
       61 cttatggtta tcgtagagtc actttagcgt taaagatgaa aggatataca atcaatcata
      121 aaacagttag aaaattaatg tcccaaatgg gacttacctg tcaaatccga ataaagcgat
      181 ataaatctta taaaggaaca gtaggaaaaa ttgccaagaa tgtgttaaaa cgaaattttt
      241 cagtagatac acccaataaa aaatgggtga cagacgtcac tgaattcaag ataaaaggaa
      301 gaaaaatcta tctatctcct atacttgatt tatttaacgg agaaataatt agttatagta
      361 tatcaactag tccaacatat aaactgattg aagaaatgct tcaacaagca attaaaaaaa
      421 agggaactga gggttcactg attctacatt cagatcaagg atggcagtat cagatgccac
      481 aatatcaaaa aaaattaaaa gagaataaca ttattcaaag catgtctaga aaaggaaatt
      541 gcttagataa ttctgtaata gaaaattttt ttggtgtgct taaatcagag tttttttatc
      601 gagaaaaatt ccgatcaatt gagatatttc aaagtaaatt aaatgagtat attaggtggt
      661 ataataacaa aaggataaaa ctaaagttaa atggactatc tccagtagaa tatcggaaac
      721 agtccattaa atagtt
//
LOCUS       DADLIO010000202          732 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.213, whole genome shotgun sequence.
ACCESSION   DADLIO010000202 DADLIO010000000
VERSION     DADLIO010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..732
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.213"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            308..706
                     /gene="spxA"
                     /locus_tag="JOX41_002944"
     CDS             308..706
                     /gene="spxA"
                     /locus_tag="JOX41_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HAY6450613.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT          264 a          103 c          134 g          231 t
ORIGIN      
        1 ataaaaaatc ttaagaaatc ggtttcattt agcttttgag ataaaataat agtacagttt
       61 tatacgctgt ttcatatgtt tagaaaattt gaattagatt tgaaaactct aatttttaaa
      121 tgataaaaaa agcgagaatg ctggttttac tgtatattaa ccttagataa ctttcatttt
      181 tttaaaaaaa ttatgaaaaa aaggtagcta tttaaaagtt gattatgtat aatagaaaca
      241 gatgggagat tattatgatc ttctgttaca aaaaagtgat tcttatcacg aaaaggagtg
      301 gtgcacgttg ttaacattat atacttcccc aagttgtact tcctgcagaa aggctcgtgc
      361 gtggttgcaa gaacatcaga ttccatttgt tgaacgtaat attttttcag aaccattgaa
      421 cagttctgaa ttaaaagcga ttttacaaat gacagaagac ggaacagaag aaatcatctc
      481 gacacgttcc aaagtattcc aaaaactgaa catggattta gatgatctgc cgttacaaga
      541 attattggaa cttgtgcaaa acaatcctgg attgcttcgc cgtccaatca tgattgatga
      601 taaacgtctg caagttggtt ttaatgaaga tgaaattcgt cggttcctac cgcgcgatgt
      661 acgacaatta gaattacgtc aagcacaatt gatggctgga ttatagaagg ataatacgaa
      721 acttggaaaa ga
//
LOCUS       DADLIO010000203          731 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.214, whole genome shotgun sequence.
ACCESSION   DADLIO010000203 DADLIO010000000
VERSION     DADLIO010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..731
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.214"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(324..524)
                     /locus_tag="JOX41_002945"
     CDS             complement(324..524)
                     /locus_tag="JOX41_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAY6450614.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
BASE COUNT          268 a          115 c          112 g          236 t
ORIGIN      
        1 tctttttcgt tgctttgctc ataaaaatct gcatattcat cactaatatt ttttctaata
       61 aattcttcca tcataaagat cacctcgaaa agagtatacg aacaaacgtt ctttttgtaa
      121 aggtggaatt tattatacta aataaatagg tgaacaagta cttgtgccaa attatgtgcc
      181 aaaaaaaatc gaatttaata aaacacaaac aaaaagaaat cctattatga taacatttct
      241 tataataaca aacacaacag aagacgtgta atagttagtc aggaacgtac aaataacccc
      301 tgtatccttt gcggtacagg gggttatttt gtataagtag acattgtagt ttctaaactg
      361 ctatgtccta aacgtttcga tacgctaagt atatttactc cttgataaag taaaatagat
      421 gcatgcgtat gtcttagtcc atcaataaac agtcgaagag aaaataggga aaaattgatt
      481 actaaagaaa aacttactag gtcgacggtg tagttgattt tcatacttca atagattcga
      541 attaaacgat ttcgattggc ttataccagt cctatccaac gaaagatata tcgttcttaa
      601 ctctagcggt ataacttgaa gctttacgta aagccaatgg gaatgaactg gagatgactt
      661 tttattattt ttagtaatag ctgatgggtt aatacttaca actttccttt tcaaagtacc
      721 atataaaaaa a
//
LOCUS       DADLIO010000204          725 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.215, whole genome shotgun sequence.
ACCESSION   DADLIO010000204 DADLIO010000000
VERSION     DADLIO010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 725)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 725)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..725
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.215"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            28..>725
                     /locus_tag="JOX41_002946"
     CDS             28..>725
                     /locus_tag="JOX41_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HAY6450615.1"
                     /translation="MLGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWD
                     GKVYVQNLFNAAGIKEPITSLDAQVRLLIWTFTNGQWMGVVQPTTVDGFKACTDPRQA
                     AYAFERNYERPAATHPERQDYAVNWYNKFKDLKPGGATGEAGLKHLESLIGQRIGNGQ
                     CYGLSAEYSGYLGGCGMGAGTKYGLTHVIGNTSAASDIGIAYDWSAVGWKVIQNPRYD
                     QLVVGAIINWARGG"
BASE COUNT          226 a          112 c          179 g          208 t
ORIGIN      
        1 ggatttacga aacaatctgc atgtggaata ttggggaaca ttcaacaaga aacaggagga
       61 acttttgatc ctgatactgt tcaaataggt ggaccagcat acggattagt tcagtgggat
      121 ggttcttcat atcctcttgt tggtccagca acatgggatg gaaaagttta tgttcaaaac
      181 ttatttaatg ctgcaggtat taaagaacca ataacgagct tagatgcaca agttcgattg
      241 cttatttgga catttacaaa tggacaatgg atgggcgtag tacaacctac gacggttgat
      301 ggatttaagg cctgtactga tccaagacaa gcagcatatg cttttgaacg aaactatgaa
      361 cgtccggcag cgacacatcc tgaacgtcaa gattatgcag ttaactggta taacaaattt
      421 aaagatttaa aaccaggagg agctactgga gaagcaggac taaaacattt agagtctttg
      481 attggacaac gaattggcaa tggtcagtgt tatggcttgt ctgcagaata ttcaggatat
      541 ctgggtggtt gtggcatggg tgctggaaca aaatatggtt taactcatgt gataggaaat
      601 acttctgcag catctgatat tggtattgcc tatgattggt ctgctgttgg ttggaaagtg
      661 attcaaaacc ctagatatga tcaattagta gttggtgcaa ttattaattg ggcaagaggt
      721 ggaca
//
LOCUS       DADLIO010000205          712 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.216, whole genome shotgun sequence.
ACCESSION   DADLIO010000205 DADLIO010000000
VERSION     DADLIO010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 712)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 712)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..712
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.216"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(<1..479)
                     /locus_tag="JOX41_002947"
     CDS             complement(<1..479)
                     /locus_tag="JOX41_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion protein ImpB"
                     /protein_id="HAY6450616.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSMNLFTTEGTRSQRRKKLAQMIQENIKEELGLLA
                     "
BASE COUNT          219 a          133 c          109 g          251 t
ORIGIN      
        1 gcaagcaatc ctagctcttc tttaatattc tcctggatca tttgagccag cttctttctc
       61 cgttgacttc ttgttccttc agtcgtaaaa agattcattg atctggtcac ttttaagatc
      121 gattcatcga tcgagtaaat caataaatct tcgtctgcta cataccttct gaaaatattg
      181 tttacctgca tatttcgctt aatatagaga ttcatgcgtg gtggaacgac atgtaacgtt
      241 ttaggaaaag gttgcggtag atctcgtggt cgactgacat tagaaatacc gtacttcttc
      301 tttgcagctg gtgaagaagc taaaatcaac cctgatcctg tattatccgc tcgactcatg
      361 acgactaatt cagtcgttaa tggatctaaa ttcctttcta tacattcgac acttgcgtaa
      421 aagcttttca tatcgatcaa aaagtaatca tttactggct cttttgaata atccatcata
      481 aataacactc cattcttcca cattatacaa acatacgttc gtttttgtaa agaagaatcg
      541 attaaatgta caaaaaaaga agcataggta agttatttcc ctacttcttc tgttgatttg
      601 taaaatcaac acattgtatc actttattaa atggatattt actattagtc ttgtgaaaat
      661 ttgaaaataa gtgtcgtatt atccagtttt gcttagttat attagaaaaa aa
//
LOCUS       DADLIO010000206          691 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.217, whole genome shotgun sequence.
ACCESSION   DADLIO010000206 DADLIO010000000
VERSION     DADLIO010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..691
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.217"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            10..>691
                     /locus_tag="JOX41_002948"
     CDS             10..>691
                     /locus_tag="JOX41_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element ISEfa7 family transposase"
                     /protein_id="HAY6450617.1"
                     /translation="MQGVIAMMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFE
                     FIYPIVEATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDTNVAYRWFLGYS
                     FEEKIPHFSTFGKNYVRRFRETTVFEDIFAYILEQAVKAGFVTEDNLYLDSTHIKANA
                     NKHKFTKEMTHDEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKLKERKISKADPE
                     SGYYVKGER"
BASE COUNT          228 a          125 c          147 g          191 t
ORIGIN      
        1 tgaaaacgaa tgcaaggagt gatagctatg atgtctaaaa acaatacgaa tggtagaaat
       61 caatttgcga tgcttacgat tgatgatcta gttcctcaag atcatctcgt tcgaaagatt
      121 gatgccgcgc ttgattttga atttatttat ccaatcgtcg aagccactta ctccgattta
      181 ggtcgcccaa gtatcgatcc agtgattctg atcaaattgg tgtttattca gtatttattc
      241 ggtatccgtt ccatgcgaca aaccattaag gaagtcgata ccaatgtcgc ttaccgctgg
      301 tttttaggct actccttcga ggagaaaatc ccccatttct caacttttgg aaagaattat
      361 gttcgccgat ttagagaaac gacggtgttt gaggatattt ttgcctatat tttagaacaa
      421 gcagttaaag caggttttgt aacagaggat aatttgtatc tggattctac ccacatcaaa
      481 gctaacgcca ataaacataa gtttacgaaa gaaatgaccc atgatgaagc gaaagcctat
      541 caggatgaat tagaagatga gatcaatcgt caacgaatag aggctggaaa acgccctttt
      601 actttggact tagaaaagga agtgaagctg aaagaaagaa aaataagtaa agctgatccg
      661 gaaagcggct actacgtcaa aggcgaacga g
//
LOCUS       DADLIO010000207          643 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.218, whole genome shotgun sequence.
ACCESSION   DADLIO010000207 DADLIO010000000
VERSION     DADLIO010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..643
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.218"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(74..345)
                     /locus_tag="JOX41_002949"
                     /pseudo
     CDS             complement(74..345)
                     /locus_tag="JOX41_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876065.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
     gene            456..>643
                     /locus_tag="JOX41_002950"
     CDS             456..>643
                     /locus_tag="JOX41_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HAY6450618.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LKQRDTVIIACVIWGIING"
BASE COUNT          225 a          112 c           96 g          210 t
ORIGIN      
        1 tggcaaaaat ttcaatcttt aaatggcgaa aaacaaagag cgtgagaccc tatccttatc
       61 tcacgctctt tgtctatttt tctaacaaat caagtatttc ttgaggagaa tcaataatta
      121 tatctacact ttgaaaattt tctatatttt tggctcccca tttagctaaa ccaaatgcta
      181 tcccacaagc tttcgcactt tgcatgtcat ataatgaatc accaatataa atcgtttctt
      241 attttttatg cccaattcat caattgcctt ttgtatgggg tccggaaaag gtttatgcaa
      301 cttagtatct gaagctgtaa tttgtatatc aaaatataga tttaacccgt ggtgctagtt
      361 aattttttcc tagaggaaaa tgtctaaaca tgttggtaaa tcaacaaaaa aacgcatata
      421 gtagtctcaa aactcccaag aaatgaggac tacatatgcg ttcatcaaaa tatactgaac
      481 attatacaga tacttttata acattcaagg aaattatgag aactgtttct aacatatacc
      541 acaattgtgt accagataag attaaaaacc gaagaaatac tgatcaactg aagcaacgcg
      601 atacagtgat tattgcttgt gttatatggg gcataattaa tgg
//
LOCUS       DADLIO010000208          608 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.219, whole genome shotgun sequence.
ACCESSION   DADLIO010000208 DADLIO010000000
VERSION     DADLIO010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..608
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.219"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(91..>608)
                     /locus_tag="JOX41_002951"
     CDS             complement(91..>608)
                     /locus_tag="JOX41_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3-like element ISEfa8 family transposase"
                     /protein_id="HAY6450619.1"
                     /translation="IVTDLTYVRVGKKWHYICLILDLFNREIIGYSCGEKKDASLVKE
                     AFGRIPYSLTDVKLFHTDRGKEFDNQTIHEILNGFGITRSLSRKGCPYDNAVVESTYK
                     SVKVEFVHQYQFETLAQLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDN
                     ERGSDTSGEAA"
BASE COUNT          174 a          143 c          112 g          179 t
ORIGIN      
        1 ttgtgaatgc tgcggtgtta tggctacgat tgcccttgac aatgagcatc ctcggatctg
       61 attttctccg gcagaagcac aatcattcaa ttacgctgcc tctccagagg tatcagatcc
      121 gcgctcatta tcaaggattc gcttcgccaa tctctgttgt cgaatttgga tcggtgtttc
      181 atacgccaac gtgccatgta agcgtagata gttccaccaa tgcacataat caaacaattc
      241 tagacgtagc tgtgccagtg tctcaaattg gtattgatgc acgaattcta ctttgacaga
      301 tttataggtt gattccacaa cggcattatc atacggacaa cccttcctac tcaatgaacg
      361 agtaattcca aaaccattca gaatctcatg aatggtttgg ttatcaaatt cctttccccg
      421 gtctgtatga aaaagcttga cgtctgttaa agaatacggt atccgtccaa aggcttcttt
      481 taccaatgag gcatctttct tctcaccaca ggaataacca ataatttctc gattaaacaa
      541 atcaagtatt aagcagatat aatgccactt tttccccacg cgaacataag taagatccgt
      601 aacgatgg
//
LOCUS       DADLIO010000209          605 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.220, whole genome shotgun sequence.
ACCESSION   DADLIO010000209 DADLIO010000000
VERSION     DADLIO010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..605
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.220"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            30..233
                     /locus_tag="JOX41_002952"
     CDS             30..233
                     /locus_tag="JOX41_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450620.1"
                     /translation="MVDKEVISEKVAEALLIPRYWTIETPLVEDAPTMLFEDLVKIAG
                     YELHYQENMETYEIEYWLTKLEN"
     gene            248..>605
                     /locus_tag="JOX41_002953"
     CDS             248..>605
                     /locus_tag="JOX41_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450621.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFAQIKKAKAMAS"
BASE COUNT          235 a          100 c          121 g          149 t
ORIGIN      
        1 tattgactgt aaaagaagtc gttcaaattt tggtggacaa agaagtcatt tctgaaaaag
       61 tagcagaagc tttacttatt ccgcggtact ggacgataga aaccccttta gtagaggatg
      121 caccgactat gctatttgaa gacctagtga agattgcagg atatgaactg cattatcaag
      181 aaaacatgga aacttatgaa atcgaatatt ggttaaccaa attagagaac taaaaaggag
      241 aaaaaatatg gctcaaaatt actatgacga atttgtcaaa ttacctttgg ataaaatggc
      301 acaaaaaatg gaggatatga cgttcctata ccatgaaaca cgtgtaccca aaaaacatta
      361 caaggaaaaa ttgtcagtcg cagtggaaga aatgattgaa tcaggtgtcg aaatgaatct
      421 cattgcgacg tactatcgaa cactggaaga actgaaaaaa caaaatggaa aatggttttt
      481 ccaagcctta ctatgcttgg aagtaggtgt caaaccaagc actatcaaac cttccgaata
      541 tcaagcctta gaactgactt atgcaaaatt cgcacagatt aagaaagcta aagcaatggc
      601 tagcg
//
LOCUS       DADLIO010000210          593 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.221, whole genome shotgun sequence.
ACCESSION   DADLIO010000210 DADLIO010000000
VERSION     DADLIO010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..593
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.221"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            <1..580
                     /locus_tag="JOX41_002954"
     CDS             <1..580
                     /locus_tag="JOX41_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAY6450622.1"
                     /translation="GIKSHLWVTQNIWGDHTDPCGYLSEMGVSKEKLAYDLAHGFTDD
                     NPTTSDDNPTTSEDKPVIDPTRAGAANSTLTDGTNYAHVDQFGEIENANLHVAGWHIA
                     NYKYEYIFIMDYNTGKELARVRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVY
                     VMMRATNDPEGNTKGGAQDFHDKRWYLNIPQR"
BASE COUNT          204 a          105 c          122 g          162 t
ORIGIN      
        1 aggaatcaaa tcgcatttat gggtaacaca aaatatttgg ggcgatcata cagatccttg
       61 cggttatctt tctgaaatgg gtgtaagtaa agaaaaacta gcctatgatt tggctcatgg
      121 ttttacggat gataatccaa ctacttcgga tgataatcca actacttcgg aggataaacc
      181 agtaattgat ccaactcgag caggtgctgc aaattctacg ctgacagatg gaacaaatta
      241 cgcccacgtt gatcagttcg gagaaatcga aaacgcaaac ttgcatgtag ctggatggca
      301 cattgctaat tataaatacg agtatatttt cattatggac tacaatactg gaaaagaact
      361 agctagagta agagctgatg ggatttatag accagacgta aatcaagctt ataatacttt
      421 aggaaatgtt ggctatcatg tatctttcaa tatgcgtgat ttccctaata agaaagtata
      481 cgtcatgatg cgtgcgacaa acgatccaga aggaaatact aagggtggag cacaagattt
      541 tcatgacaag cgttggtatt taaatattcc acaacgataa aaaattcccc cct
//
LOCUS       DADLIO010000211          571 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.222, whole genome shotgun sequence.
ACCESSION   DADLIO010000211 DADLIO010000000
VERSION     DADLIO010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..571
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.222"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            6..>571
                     /locus_tag="JOX41_002955"
     CDS             6..>571
                     /locus_tag="JOX41_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HAY6450623.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIK
                     YLNNLIEQDHRPVKRRNKFYRSLRTASTT"
BASE COUNT          199 a          100 c          110 g          162 t
ORIGIN      
        1 tgacgatgaa tcattttaaa ggaaagcaat ttcagcagga tgtgattatt gtagccgtgg
       61 gctactatct tcgttataac cttagctatc gtgaagttca agaaatctta tatgatcgtg
      121 gcattaacgt ttctcatacg acgatttatc gttgggtgca agaatatggc aaactactct
      181 atcaaatttg gaaaaagaaa aataaaaaat ccttttattc atggaaaatg gatgaaacgt
      241 acatcaaaat taaaggaaaa tggcattatt tgtatcgagc catcgatgca gatggtttaa
      301 ccttggatat ttggttacgt aaaaaacggg acacacaagc agcctatgct tttcttaagc
      361 ggttagtgaa gcagtttgat gaaccgaagg ttgtagtcac agataaagcc ccctctatta
      421 caagtgcctt taagaaacta aaagaatacg gcttttatca agggacagaa catcgtacca
      481 ttaaatacct gaataatttg attgaacaag accatcgtcc agtaaagaga cgcaataaat
      541 tctatcgaag tttacgcact gcctctacca c
//
LOCUS       DADLIO010000212          532 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.223, whole genome shotgun sequence.
ACCESSION   DADLIO010000212 DADLIO010000000
VERSION     DADLIO010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 532)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 532)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..532
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.223"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(51..353)
                     /locus_tag="JOX41_002956"
     CDS             complement(51..353)
                     /locus_tag="JOX41_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450624.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
BASE COUNT          183 a           92 c           75 g          182 t
ORIGIN      
        1 aagtatggtg ataaaatccg ttccgggcta ccttttttag gtagcctact ttaatcttta
       61 tacctttctg gatcaacgaa agtatacttc aaatagtcat aacgccgatg atcgctccgt
      121 gcgtctggca catcagtcac gatatcaaac aaaaaataca catctttctt cattctggtt
      181 tttgttgccg gaattttaaa gtagttctta ttagagtaat agagattgat taataagcta
      241 tcttcgattg ctaaaaagaa aacttctgaa tcccacacct tataaaaatc tttgacaaat
      301 ctattcgaag gatcaaattt aaaccataat tgtgtttttc cttccatcaa cataatgttc
      361 acctcaaaaa gagtatacga actaatgttc tttttgtaaa gtaggaatat cattgataat
      421 atggatggaa catatatatt aaaaagtgtt ctttttgaat gctattttga atgccatttt
      481 cattcattta acgaaaatct gcgaaaataa aaaatgctca aacccttata aa
//
LOCUS       DADLIO010000213          528 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.224, whole genome shotgun sequence.
ACCESSION   DADLIO010000213 DADLIO010000000
VERSION     DADLIO010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.224"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(5..90)
                     /locus_tag="JOX41_002957"
     tRNA            complement(5..90)
                     /locus_tag="JOX41_002957"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(54..56),aa:Leu,seq:taa)
     gene            complement(107..178)
                     /locus_tag="JOX41_002958"
     tRNA            complement(107..178)
                     /locus_tag="JOX41_002958"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(144..146),aa:Gly,seq:gcc)
     gene            complement(190..262)
                     /locus_tag="JOX41_002959"
     tRNA            complement(190..262)
                     /locus_tag="JOX41_002959"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(227..229),aa:Thr,seq:tgt)
     gene            complement(280..361)
                     /locus_tag="JOX41_002960"
     tRNA            complement(280..361)
                     /locus_tag="JOX41_002960"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(325..327),aa:Leu,seq:tag)
     gene            complement(369..441)
                     /locus_tag="JOX41_002961"
     tRNA            complement(369..441)
                     /locus_tag="JOX41_002961"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(406..408),aa:Lys,seq:ttt)
     gene            complement(445..517)
                     /locus_tag="JOX41_002962"
     tRNA            complement(445..517)
                     /locus_tag="JOX41_002962"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(482..484),aa:Val,seq:tac)
BASE COUNT          135 a          152 c          128 g          113 t
ORIGIN      
        1 gaaatgccga ggaccggaat cgaaccggta cggtgatcac tcaccgcagg attttaagtc
       61 ctgtgcgtct gccagttccg ccaccccggc gcgattgctt tggcaaagcg gaaaacgggg
      121 ttcgaacccg cgacccccac cttggcaagg tggtgctcta ccactgagct atttccgcgt
      181 gtttaaagat gccggctaaa ggacttgaac cctcgaccct ctgattacaa atcagatgct
      241 ctaccaactg agctaagccg gcatgtaaaa cttaaattat gcgggtgaag ggacttgaac
      301 ccccacgccg taaggcgcta gatcctaaat ctagtgcgtc tgccaattcc gccacacccg
      361 caaaaatatg agccgtacag ggctcgaacc tgtgaccctc tgattaaaag tcagatgctc
      421 taccaactga gctaacggct catatggagg ttaacgggat cgaaccgctg accctctgct
      481 tgtaaggcag atgctctccc agctgagcta aacctccatg gataactt
//
LOCUS       DADLIO010000214          521 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.225, whole genome shotgun sequence.
ACCESSION   DADLIO010000214 DADLIO010000000
VERSION     DADLIO010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 521)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 521)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..521
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.225"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            25..>521
                     /locus_tag="JOX41_002963"
     CDS             25..>521
                     /locus_tag="JOX41_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HAY6450625.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDAT"
BASE COUNT          190 a           95 c           86 g          150 t
ORIGIN      
        1 attcacagaa aagaggactt ccctatgaat gattttacta cagaaattgt gcaaactcta
       61 gtcactaaag gcgatttaaa tgaattattc cgttcgcact tagaaaaagc gataaacaca
      121 ctcctacgga ctgaattaac ggctttttta gattacgaaa aatatgatcg cactggtttt
      181 aattcaggta attcgagaaa cggttcttac tttcgatcaa tcaaaaccga atatggtgaa
      241 ttaacattgg aaatacctag agatcgtaat ggtgagttta aacaacaaac tttaccagcc
      301 tacaaaagaa caaacgatac attggaaacc actattatcc atttattcga aaaaggtgtt
      361 acgatgtctg aaattgctga tttgatcgaa aaaatgtacg gtcatcacta tactccacaa
      421 accatgtcca acatgactaa agttctgact gaagaagtaa atgcctttaa atccagagcc
      481 ttaaatgata agtatgtcgc tatttttatg gacgctactt a
//
LOCUS       DADLIO010000215          520 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.226, whole genome shotgun sequence.
ACCESSION   DADLIO010000215 DADLIO010000000
VERSION     DADLIO010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..520
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.226"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            <1..508
                     /locus_tag="JOX41_002964"
     CDS             <1..508
                     /locus_tag="JOX41_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
                     /protein_id="HAY6450626.1"
                     /translation="DLTYVRVGKKWNYVCFILDLFNREILGYSCGEHKDAVLVKKAFS
                     RIKQPLTEVEIFHTDRGKEFDNQAIDELLTTFDINRSLSHKGCPFDNAVAESTYKSLK
                     VEFVYQYTFETLQQLDLELFDYVNWWNHLRLHGTLGYETPVGYRNQRLAQRILDNELG
                     CANASEAV"
BASE COUNT          158 a           91 c          111 g          160 t
ORIGIN      
        1 agacttgact tatgtacgag tcgggaaaaa atggaattat gtctgtttca ttttggatct
       61 gttcaatcga gaaattctcg gctattcttg tggagaacat aaagatgccg ttctagtaaa
      121 aaaagcattt agccgtatca aacaacctct gacagaggtt gagatttttc atactgatcg
      181 tggaaaagag tttgataacc aagctattga tgaattatta acaacttttg acatcaatcg
      241 atcattgagt cataaaggct gtccttttga taatgccgta gctgaatcaa cttataagtc
      301 gttgaaagta gaatttgtct atcaatacac atttgaaacc ttacaacaat tggatttgga
      361 gttatttgac tatgtcaatt ggtggaacca ccttcggttg cacggtacac ttggctacga
      421 gacaccggtt ggttaccgta accagagatt ggcgcagcga atccttgata atgagctcgg
      481 atgtgctaac gctagcgagg cagtctaact ttaactgtta
//
LOCUS       DADLIO010000216          517 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.227, whole genome shotgun sequence.
ACCESSION   DADLIO010000216 DADLIO010000000
VERSION     DADLIO010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..517
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.227"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            57..>517
                     /locus_tag="JOX41_002965"
     CDS             57..>517
                     /locus_tag="JOX41_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAY6450627.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYS"
BASE COUNT          191 a           72 c          105 g          149 t
ORIGIN      
        1 ataaatatgt tataatagta tcaaatgaat attgctaaaa gaaaagaggt aggaacgtgg
       61 tagcgaagaa atatgtaatc ggtaatttta aaggtggcgt aggtaaaagt acgtgcgcgc
      121 aaatgttagg gtttgaatca gcagttaatg aaggaaaaag aaccttgata attgacttgg
      181 atatgcaagg aaatacttct gatgtgatga acttaacgca tatgaacttc actaacgaag
      241 aaggaggcgg agaaggtgaa ccgattgttt acgaaaatac tgtgactgac gtgttgataa
      301 acaatcttcc acctaaagag gctgtctata aagtaatcaa taacctctat atacttccag
      361 cagacatgtc ctttgaaatg tatgatgatt ggatcaaaga ccaatataat gattcattat
      421 cccaattcaa atatatgaaa gaaaagctag aaccattatt tgatgagttt gacgtcatct
      481 atttagatgt cccaccttct atttctgtat atagtaa
//
LOCUS       DADLIO010000217          514 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.228, whole genome shotgun sequence.
ACCESSION   DADLIO010000217 DADLIO010000000
VERSION     DADLIO010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..514
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.228"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(<1..132)
                     /locus_tag="JOX41_002966"
     CDS             complement(<1..132)
                     /locus_tag="JOX41_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAY6450628.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          186 a           94 c           92 g          142 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactattag acaa
//
LOCUS       DADLIO010000218          496 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.229, whole genome shotgun sequence.
ACCESSION   DADLIO010000218 DADLIO010000000
VERSION     DADLIO010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..496
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.229"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            <1..327
                     /locus_tag="JOX41_002967"
     CDS             <1..327
                     /locus_tag="JOX41_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016204422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAY6450629.1"
                     /translation="KKASLKSLKDTWLDLSEDNPYSQFLITVMAGVNQLERDLIRMRQ
                     REGIELAKKEGKFKGRLKKYHKNHAGMNYAVKLYKEGNMTVNQICEITNVSRASLYRK
                     LSEVNN"
BASE COUNT          199 a           66 c           90 g          141 t
ORIGIN      
        1 aaaaaggcaa gtttaaaatc actaaaagat acatggcttg atttatcaga agataatcca
       61 tacagccaat tcttaattac tgtaatggct ggtgttaacc aattagagcg agatcttatt
      121 cggatgagac aacgtgaagg gattgaattg gctaagaaag aaggaaagtt taaaggtcga
      181 ttaaagaagt atcataaaaa tcacgcagga atgaattatg cggtaaagct atataaagaa
      241 ggaaatatga ctgtaaatca aatttgtgaa attactaatg tatctagggc ttcattatac
      301 aggaaattat cagaagtgaa taattagcca ttctgtattc cgctaatggg caatattttt
      361 aaagaagaaa aggaaactat aaaatattaa cagcctccta gcgatgccga aaagcccttt
      421 gataaaaaaa gaatcatcat cttaagaaat tcttagtcat ttattatgta aatgcttata
      481 aattcggccc tataat
//
LOCUS       DADLIO010000219          487 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.230, whole genome shotgun sequence.
ACCESSION   DADLIO010000219 DADLIO010000000
VERSION     DADLIO010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.230"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(<1..>487)
                     /locus_tag="JOX41_002968"
     CDS             complement(<1..>487)
                     /locus_tag="JOX41_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HAY6450630.1"
                     /translation="IHRRFYTSICHQKITTDTTEFKYHEVDAKGIIRQKKLYLDPFMD
                     MFNSEILSYRISEKPNALAVMEGLEEAIQTTNDCPYRRTFHSDQGWAYQMKAYRNKLK
                     EYKIFQSMSRKGNCLDNSLMENFFGLLKQEIFHGKVYNCFEELKSAIDSYIYYYNNER
                     IK"
BASE COUNT          142 a           92 c           86 g          167 t
ORIGIN      
        1 gttttatccg ttcattattg tagtaataga tatagctatc gatggctgat tttaattcct
       61 cgaaacagtt ataaactttc ccgtgaaaaa tctcttgttt taataagcca aaaaaattct
      121 ccataagtga attatctaag cagttccctt tccgagacat gctttgaaag attttgtact
      181 ccttcaattt gtttctataa gctttcattt gatacgccca accttgatct gagtgaaacg
      241 tacgacgata gggacaatcg ttagtggtct ggatagcttc ctccaaacct tccattaccg
      301 ctaatgcatt gggcttttca gagatacgat aggataaaat ctcactattg aacatatcca
      361 taaaaggatc tagatacaat ttcttttgac ggataatgcc tttggcatcc acttcatggt
      421 atttaaattc agttgtatcc gtcgtgattt tctgatggca gatactggtg tagaaacgac
      481 gatggat
//
LOCUS       DADLIO010000220          481 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.231, whole genome shotgun sequence.
ACCESSION   DADLIO010000220 DADLIO010000000
VERSION     DADLIO010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.231"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(<1..449)
                     /locus_tag="JOX41_002969"
     CDS             complement(<1..449)
                     /locus_tag="JOX41_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAY6450631.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYLK"
BASE COUNT          136 a           94 c           61 g          190 t
ORIGIN      
        1 ttttttaaat atgcgttctc tgctcttaaa cgaataactt cttcttcaag agactcatct
       61 ttaagttttt taggaatgtt tagcttggaa ttcatactaa tttttctgcc ccttttttgg
      121 ctctcaagtg aagaagcacc gccttcttca tattgctcta tccatttact tagagttcta
      181 tttgaaccga tattaaattt tttagcagtt tcttggatag aaagaccatt tgtttccata
      241 tattctataa catcaagttt aaattttgta gtgtagcttt tgccacctcc aaccaagcct
      301 tcccaaccat gatagttata aatccttacc caatgtctaa ccagtgtacg atttatttga
      361 tatttatgtg caagatattt gtagccgcct tcgttattta aatagtctga aactactttt
      421 ttcttaaaaa caaatgtata tttccgcaaa aaaagcaccc cttttaatta gatttctagt
      481 c
//
LOCUS       DADLIO010000221          476 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.232, whole genome shotgun sequence.
ACCESSION   DADLIO010000221 DADLIO010000000
VERSION     DADLIO010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.232"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            22..>476
                     /locus_tag="JOX41_002970"
     CDS             22..>476
                     /locus_tag="JOX41_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAY6450632.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNF
                     LKCGGTALEYFEQYKENKRRCGRTEIIFPAEEKEYIEKRSTEGWTPDVIIGRAERTFS
                     CSVSTLYRRFKTGEFNVLHLPMQGKRKPNGYKEKRGKQAFKRNISERKK"
BASE COUNT          178 a           87 c           95 g          116 t
ORIGIN      
        1 atacaaggag agtgaacata aatgacttat acccatctta caccaaacga gcttgtaatg
       61 atagaagcat attttcatca agaaactccg gttgctatcg ttgcgaagca gcttaaacgt
      121 ggacgccaaa caatttacaa tgtctataac tttctcaaat gtggtggaac agcacttgaa
      181 tactttgaac aatacaaaga aaataagcga cgttgtggga gaaccgaaat catttttcct
      241 gctgaggaaa aagaatacat tgaaaaaaga tcaactgaag gttggacccc agacgtcatt
      301 attggccgtg cagagcgaac cttctcttgt tcagtaagta ccctctatcg ccggtttaag
      361 acgggagaat tcaatgtttt acatttaccg atgcaaggaa aacgaaaacc aaatggttat
      421 aaggaaaaac gtggaaaaca ggcattcaaa agaaatattt ctgaacgtaa aaaaga
//
LOCUS       DADLIO010000222          473 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.233, whole genome shotgun sequence.
ACCESSION   DADLIO010000222 DADLIO010000000
VERSION     DADLIO010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.233"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            <1..>473
                     /locus_tag="JOX41_002971"
     CDS             <1..>473
                     /locus_tag="JOX41_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HAY6450633.1"
                     /translation="YLWKKKNRQSFYSWKMDETYIKIKGRWHYLYRAIDADGLTLDIW
                     LRKKRDTQAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFRKLQSVGLYTKTEHRTVKY
                     LNNLIEQDHRPIKRRNKFYQSLRTASSTIKGMETIRGIYKKNRRNGTLFGFSVST"
BASE COUNT          161 a           92 c           95 g          125 t
ORIGIN      
        1 attatctttg gaagaagaaa aatagacaat ccttctattc atggaaaatg gacgaaacct
       61 atatcaaaat taagggacgt tggcattatc tttatcgtgc aattgatgcg gacggcttaa
      121 ccttagatat ctggttacga aagaaacggg atacgcaagc agcctatgct ttcttaaaac
      181 gactccataa acagtttggt gagccgaaag caattgtgac cgataaagca ccttctcttg
      241 gctccgcctt tagaaagtta cagagtgtgg gtttatatac taagacagag caccgaactg
      301 tgaagtatct taacaattta atagaacaag accatcgacc tattaaacga cgaaataaat
      361 tttatcaaag tctccgtaca gcctcttcca cgattaaggg catggagacc attcgaggaa
      421 tatataaaaa gaaccgaaga aatggaacgc tcttcggctt ttcggtgtct act
//
LOCUS       DADLIO010000223          460 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.denovo.234, whole genome shotgun sequence.
ACCESSION   DADLIO010000223 DADLIO010000000
VERSION     DADLIO010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.denovo.234"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(20..91)
                     /locus_tag="JOX41_002972"
     tRNA            complement(20..91)
                     /locus_tag="JOX41_002972"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56..58),aa:Glu,seq:ttc)
     gene            complement(113..200)
                     /locus_tag="JOX41_002973"
     tRNA            complement(113..200)
                     /locus_tag="JOX41_002973"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(164..166),aa:Ser,seq:gct)
     gene            complement(225..298)
                     /locus_tag="JOX41_002974"
     tRNA            complement(225..298)
                     /locus_tag="JOX41_002974"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(262..264),aa:Ile,seq:gat)
     gene            complement(312..382)
                     /locus_tag="JOX41_002975"
     tRNA            complement(312..382)
                     /locus_tag="JOX41_002975"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(348..350),aa:Gly,seq:tcc)
     gene            complement(384..459)
                     /locus_tag="JOX41_002976"
     tRNA            complement(384..459)
                     /locus_tag="JOX41_002976"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(424..426),aa:Asp,seq:gtc)
BASE COUNT          132 a          128 c          108 g           92 t
ORIGIN      
        1 taaaactata ttaaattaat gacccgtacg ggattcgaac ccgtgttacc gccgtgaaag
       61 ggcggtgtct taaccgcttg accaacgggc caggtaaaac aaaatattga aacggagaag
      121 gagggatttg aaccctcgcg ccggtttccc gacctacacc cttagcaggg gcgcctcttc
      181 agccacttga gtacttcccc aaaaccaata agattttgta ctaatgggcc taaatggact
      241 cgaaccatcg acctcacgct tatcaggcgt gcgctctaac cagctgagct ataggcccat
      301 aaaaaactaa aagcgggtga cgagaatcga actcgcgaca acagcttgga aggctgtggt
      361 tttaccacta aactacaccc gcatggcggt tccgacggga atcgaacccg cgatctcctg
      421 cgtgacaggc aggcatgtta acccctacac cacggaacca
//
LOCUS       DADLIO010000224        17753 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.guided.051, whole genome shotgun sequence.
ACCESSION   DADLIO010000224 DADLIO010000000
VERSION     DADLIO010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17753
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.guided.051"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            <1..794
                     /locus_tag="JOX41_002977"
     CDS             <1..794
                     /locus_tag="JOX41_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAY6450634.1"
                     /translation="SSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASL
                     EGYTEGNPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDT
                     TLAFLDKQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQIT
                     GLEKKIEQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLS
                     DFLPIVLSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            1052..2554
                     /locus_tag="JOX41_002978"
     CDS             1052..2554
                     /locus_tag="JOX41_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HAY6450635.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            2621..3148
                     /locus_tag="JOX41_002979"
     CDS             2621..3148
                     /locus_tag="JOX41_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAY6450636.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            3359..4420
                     /locus_tag="JOX41_002980"
     CDS             3359..4420
                     /locus_tag="JOX41_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAY6450637.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            4423..5319
                     /gene="murQ"
                     /locus_tag="JOX41_002981"
     CDS             4423..5319
                     /gene="murQ"
                     /locus_tag="JOX41_002981"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HAY6450638.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            5333..7315
                     /locus_tag="JOX41_002982"
     CDS             5333..7315
                     /locus_tag="JOX41_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAY6450639.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(7380..7826)
                     /gene="nrdI"
                     /locus_tag="JOX41_002983"
     CDS             complement(7380..7826)
                     /gene="nrdI"
                     /locus_tag="JOX41_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HAY6450640.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            8037..9461
                     /locus_tag="JOX41_002984"
     CDS             8037..9461
                     /locus_tag="JOX41_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAY6450641.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(9642..10415)
                     /locus_tag="JOX41_002985"
     CDS             complement(9642..10415)
                     /locus_tag="JOX41_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAY6450642.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(10412..11317)
                     /locus_tag="JOX41_002986"
     CDS             complement(10412..11317)
                     /locus_tag="JOX41_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAY6450643.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(11471..11791)
                     /locus_tag="JOX41_002987"
     CDS             complement(11471..11791)
                     /locus_tag="JOX41_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HAY6450644.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            12265..12951
                     /locus_tag="JOX41_002988"
     CDS             12265..12951
                     /locus_tag="JOX41_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HAY6450645.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            12953..13897
                     /locus_tag="JOX41_002989"
     CDS             12953..13897
                     /locus_tag="JOX41_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HAY6450646.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            14096..14740
                     /gene="pcp"
                     /locus_tag="JOX41_002990"
     CDS             14096..14740
                     /gene="pcp"
                     /locus_tag="JOX41_002990"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HAY6450647.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            14819..16096
                     /locus_tag="JOX41_002991"
     CDS             14819..16096
                     /locus_tag="JOX41_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450648.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            16354..17571
                     /locus_tag="JOX41_002992"
     CDS             16354..17571
                     /locus_tag="JOX41_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAY6450649.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEESTLRSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFSNRLTPYALTLIRLFPHPDFVLASTRTKIKNKLINETRKKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQKKALATQMIKKAEGSPCFLLYQTFP
                     GIGALTAALLLGELGDITRFKTHKQLNAFVGIDIRRYHSGKYTGQDRINKRGNPKARK
                     IIFFTIRNMIRQQRAAPNHIVDYYYKLKKQPIPKKDKVATVACMNKLLKCMHAMVRAH
                     TEYDYAYAVSVDH"
BASE COUNT         5716 a         3183 c         3788 g         5066 t
ORIGIN      
        1 cttccagtta tgccttagga gaacttatta aagatgcact gcttcaagaa gtagaacaaa
       61 ttattgtcac tttaggagga agcgggtgta gcgatggtgg tctaggatta ctccaatcct
      121 tgggtgcttc tttagaaggg tacacagaag gaaatccttt attatctact aaaaaacttc
      181 attttgatcg aagaaacgtt cttgtttcta aagtaaaatt gattatcgct gcagatgtta
      241 ccaatccata tacaggtcaa caaggagctg cttggcaatt tggaagacaa aaaggaggaa
      301 tagatacgac gctagctttc ttagataaac aagcaggaaa gattgctcag caaataaaag
      361 atttctggga ggtggattta gatgatattc caggaagtgg agcagcaggc ggtattggtg
      421 gagccctttt tttgttggga gcgaagatgg tttctggttt cgatttagtc agccaaatca
      481 ctggattgga aaaaaagatc gaacaagcag atgtcatcat tacaggagaa gggcggatcg
      541 atcagcaaac gatccacgga aaagttccat acggtgtagc agtgcttgca aaaaaatatc
      601 gaaaaccaat aatcgctatt tgcggaagta gagaccaaga gctagaagga ctttctgatt
      661 ttctcccaat tgtcttaagt attcatttgg gtccaatagg tttagaagaa gcaatggaac
      721 acaggcaaac attagaaaaa acaaaaatct taggacagac acttagcaga tttttcacca
      781 tcctcccgaa gtagttgaca aaatcatttt ctttatgcta tcgtaatttc aaatatagga
      841 caaagtgagg gatccgtgca ttgaaaaatt aagtcgattg atgaaagctg cattcagact
      901 gtaccttgtg gagacaagga agcagtgtgc agattttcgg gattggcttg gttttttcga
      961 tgtatgggtc tttttgtgtg tatccaaccc ttgcatcctc tttagccagt tctgaaaata
     1021 ggactggtct ttttttacga ggtgatggaa aatgtctaaa atcgaaataa aaaatctgac
     1081 attcggctac gacagccaag gcacattatt atttgaacaa gcaaatctaa attttgacac
     1141 acaatggaaa ctaggactta tcggacgaaa cggtcgagga aagacaactt tactgaatat
     1201 tctacaaaac aaactacctt atcaagggca agtaatccat cagcaagaat ttgcctattt
     1261 cccgcaacag acaaaagata aagaacgttt aacctattac gtgttaaatg atattacgga
     1321 ttttgagata tgggaaatcg aaagagagct ccaattgatg caaacagatc ctgaaatctt
     1381 atggagagaa ttcagcacac tatcgggggg agagaagaca aaagtcctac tggcactttt
     1441 atttgtggat gacactcatt tcccgttaat cgatgaacca acgaatcatt tggatatctc
     1501 tggtagaaaa caagtagcgg cttatttgaa aaagaaaaaa caaggcttca tcgtggtcag
     1561 ccatgaccgg ggatttatcg atgaagtagt ggaccatgtt ttagcaatcg aaaaaagtca
     1621 actggaactt tatcaaggga atttctctat ctatgaagaa cagaaaaaac ttcgtgatga
     1681 atttgaaatg gctcaaaatg aaaaattgaa aaaagaagtc agtaggctaa agaaaacagc
     1741 agctgaaaaa gccgaatggt ctcgttcccg agaaggagat aaaacaaaga aacaagtcgg
     1801 attcatcgat actgaatcta gacgagtgaa taaaggagca gtgggtgctg atgctgcacg
     1861 gacgatgaaa cgatccaaag caatcgtgaa tcggatggag acccagatca gcgagaaaga
     1921 aaaactatta aaagatatcg aatatatcga ttctttgacg atgaatagcc aagcgtctca
     1981 ccataagcga cttttaagcg tagaagatct tcaattaggg tatgaaaatc tgttattcga
     2041 gccaattcat tttacaatcg agcctcatca gcgggtggcg atttcaggtc ctaacggtgc
     2101 aggaaagtca tccattatcc attatcttct gggggcattc aacggcaagg ttataggaga
     2161 aaaataccag ccaaaacatc tgagcattag ttatgcaagc caaaattatg aagacaatcg
     2221 aggaacgttg gcggaatttg cagagaaaaa ccaagtagac taccaagcat ttttgaacaa
     2281 cctccgaaag cttgggatgg aaagagatgt ttttcataac aagatcgagc agatgagtat
     2341 gggccaacgg aaaaaagtgg aattggctaa atctttatca cagccagctg aactatatac
     2401 atgggatgaa ccattgaatt atttggatgt cttcaatcaa gaacaattag aacaactgat
     2461 cttgaacgtg aaacctgcca tgttactagt ggaacatgat caaaccttcc tggataaagt
     2521 atctactgag attatttctc ttgagagaat ctaacccttg taatctcaag aacaacaagg
     2581 tatggttaag gggaactttg ccaacgaagg agagaatcac atgctttatg taacgagaca
     2641 cggagaaaca acttggaacg cacaaggatt agtttgcgga cgggcagatg tgccgctgac
     2701 tgaaaaagga cagatgcagg cacagaaact agcagaaaag gtagtagatt tgcctgttcc
     2761 aatcacgaaa atcatccatt cccctcttca acgagcaaga gatacagcac aagcagttgc
     2821 tgatcgtctc agcttgccgc tgaccgttga tgaacgattg gtagaaatgg attttgggga
     2881 ttatgatgga ctgccaagca aagatgagaa ctttcaaaaa gcacgtttag cgttcgctgt
     2941 acgattccca aatggggagt cagtcttaga tgtgtatgca cggatcgttc ctttattgaa
     3001 agaatgcatc gaagacgaag aaaatgtcta tctgttagtt tgccataatg ccttgataag
     3061 agtgatcaat gcttattttc atccgatgcc taatgagggg ttctttacat tcatggtaga
     3121 taatacagaa ttggtttctt atgagtaatt atgtttttgt gttatttaaa taaaatattt
     3181 caaggcactg cttttgctta gcagtgcctt ttttaggtta tgacaattct tttgataata
     3241 taaactcaac ctttagaaat gaaatttaat tattttaata aaagtattga aattttgttt
     3301 ctttagatat atactctagt catagaaatg aagacggata cagaaaaaga gggataatat
     3361 gtttggcttt tcaatattta tgaacgattc tttgtcagaa gagaagaaac agtatatccg
     3421 ccaaatggca tccaatggct ttgtcggtat tttcacttcc atgcatatac cagaagatga
     3481 tgtttcggca tatcaaaagc gattgatcga actaggaagc gaagcgaaaa agaataaact
     3541 agaattgatg gtcgatattt caggagaggc attggaacga gcgggttttt cattagaaga
     3601 tctaacgcct ttgaaagcaa ttggtgtaac aggtttaaga atggattatc atatttccaa
     3661 tcagcagatt gccgactggt cacatcaatt gaaaatcagt ttgaatgcta gcacgatcac
     3721 gcctaaagat atcgatgaat tgaaagaagc agaagctgat ttctcacaga ttgaagcttg
     3781 gcataattat tatccacgtc ccgaaacagg gctggacaaa gaatggtatc agaaaaaaaa
     3841 tcaatggctc aaaattcaag gtctccttgt ccaaggtttt gtaccaggag atacagagtt
     3901 gagaggccca ctatatcaag gattgccaac tttggaagaa catcgaggga tccatcctct
     3961 tgcaggcgct ctagatctat tagcaagtaa cacggatatt gtttacatcg gagatgcagg
     4021 tctgtcagaa aacgttcagg agcaatttgc ttctttccaa aaagaacaga cagtcttgct
     4081 ccatacggaa cctgtagatg aagaatttta cgaatatata ttagggaagc atacgaatcg
     4141 gcaagacgat gcaagagatg tcatacgaag cgtagatgca cgttttcgag agattccgcc
     4201 tatcccagca agaaatacag ctacgcgtat gaaagggtct attactttag ataacgaaaa
     4261 gtatttgcgc tatatgggtg agatccaatt aaccaaatat gatttgccag cggatgaaaa
     4321 agtgaatgta gtagctaaag ttatcaaaga agagctacca ttgatcaacc aaatcaaagc
     4381 tggtatgaac tatcaattta taagaaaaga aggaagataa aaatgagcaa aatcaattta
     4441 gagaacctaa caacggaacg cagaaaccaa gaaacttttg gattagatga gatgagtatt
     4501 tctcaagccg ttcaactaat gaacaaagaa gatcagaaag tggccgctgc ggttgaaaaa
     4561 gaactgacaa gtatcgaacc agtgattgct aacacgattg agtcctttaa aaaaggtgga
     4621 cgtctgattt atatgggagc cggaacaagt ggaagactag gtgtgttaga tgctgctgaa
     4681 tgcgtaccga cattcggtgt agaaccggaa atggtcatag gtctaattgc tggtggagaa
     4741 gaagcaatga ctgtagctgt cgaaggggcc gaagattctt atgagctagg gcaagaagat
     4801 ctaatcaagc tgaatttgac aaaaaatgat atagttattg gtatcgcagc tagcggtcgt
     4861 acaccatatg tgatcggtgg attagattac gcaaaatcga tcggtgctgt cacaggaacg
     4921 atttcttgca ataaacaagc cgaaatcagt aaacacgcgg atttcccaat cgaagtcgat
     4981 gcaggtccag aatttttgac aggctctact cgattgaagt caggaacagc acaaaaactt
     5041 atcttgaata tgatttctac tatcagtatg attggtatag gtaaagtatt caataacttg
     5101 atggtcgatg tcaaaccaac aaatgaaaaa ctaatcgaac gctcaaaacg aatcatcatg
     5161 caagcgacag aagctgatta cgaaacagct gaaaagtact ttgaagaagc agatcaaaat
     5221 gttaagctgg ctatcgtcat gattttgaca aatagtgata aagaggaagc tcaagcaaaa
     5281 ttagctgaag caaacggatt tgtaaaaggg accttatgag ggggaaaaga ccatggcaaa
     5341 aaacgaactg actttggaag aactggcaaa acaaatttat aaaggggcag gcggcatggg
     5401 caatgtagaa agcattgtcc actgcatgac tcgtgtgcgt atgaagatca tcaatgatga
     5461 tcttgtaaat gtctctgaat taaaagcgat tccaggagtg cttggtgtag tagaagatga
     5521 acagcttcaa gtcatcatcg gacctgggaa agtgaacaaa gtagcacagc aaatggttga
     5581 tttggcaggc gtgaaattag gagaaaaact ttcttctgta agtacagcta cagcaaattc
     5641 atcagcatct ggaaaagacc gtgtaaacga acgggcacaa gaaatgaaag cggcacaaaa
     5701 atcgaaacaa aaaccatcta aaatcaaatc ggtattaaaa gacatttcta atatctttgt
     5761 gccaatgatt cctgcatttg tcggtactgg gatcgtggca gggattgccg cagttttagc
     5821 aaacttagtc acagccggaa cacttgatgc agcaacatgg caacaatata tcgatgtgat
     5881 gaacatcttg aaaaacggga tgtttagcta cctagttatc tatacaggta tcaatgctgc
     5941 acaagttttt ggtgcaacac caactcttgg tggagttatc ggggccgttg tgatgctgac
     6001 agggatgaat ccggaagcac cactgaaaaa cttatttact ggtgaagctc ttgcagctgg
     6061 acaaggtggg atcctaggtg tcatcttcgc tgtttggcta ttgtcaatcg ttgagaaaaa
     6121 actgcataaa gtagtacctg atgcggtaga tatcatcgtt acaccaactc tttcattgat
     6181 tgccatcggt ctgattgaaa ttttcttcat catgccttta gcaggtttca tttctgatgg
     6241 catggtcggt gggatcaact gggtacttgg cgttggtgga gcatttgccg gcttcgttct
     6301 aggcacatta ttcttgccga tggttatgtt cggactgcat caaattttga ctccaatcca
     6361 tgtgcaaatg attgatgaaa ctggtcgtac gctattgctt ccaattcttg cgatggctgg
     6421 tgcaggacaa gtgggtgcag cattggcatt atggattcgc tgcaaaaaag ataaagaatt
     6481 aacagaaatg atcaaaggag ctttaccagt cgggatccta ggaatcggcg aaccattgat
     6541 ttacggagta acattacctc taggacgccc atttattact gcttgtatcg gtggaggtat
     6601 cggcggggca gtgatcggaa tgatcggaaa tgtcggggct atcgctattg gaccttcagg
     6661 agccgctttg atcccattga tctctgacgg taaatggtta ggctacatcc ttggattatt
     6721 ggcagcttat gctggtggct tcgttgctac attcttcttc ggtattccta aagaccgttt
     6781 agaaaaagaa gaattagcga ctgaaacagc cacagtaaat gaagtgcctg aaaaagtagt
     6841 acctcaaact tcagctgaaa gtgtgactat cctctcatca gttgctgacg gaacagttgt
     6901 ttctttagat aaagcaagtg atccagtttt tgcacaaaag atgatgggtg aaggctactt
     6961 tgtagaacca gaaaacggac atatctattc tccagttact ggggtagtca gctctgtctt
     7021 cccaacgaaa cacgctattg ggatcacaac gccaaatggt ttagaaatct tgcttcatat
     7081 gggaatcaac acagttgact taggcggtac gccatttgat gtgaaagtaa cagaagggca
     7141 gcaagtgaca cctgatacgc ttgtagcaga agctgactta gaagcgatca aagcagcagg
     7201 caaagaaaca tccatgatcg tcttggtaac caatatggat cgtgtaaaaa actttgtctt
     7261 ggaaaaaaca ggtaaagcaa aagcaaaagc acctgtgatg gatgtcaaag cttaatatga
     7321 tagaaacaat agaaacgaaa gaagaaactg aaatctattt ttcagcttct tcttttttat
     7381 tatttattgt tttctgctaa aatctgataa attcgtgtca catcagatgg tgttccccgt
     7441 aattcataat ctgccaagaa aggaaagcca aatgtttgtg catattgttt ggctgttaga
     7501 caatactgat tattgaagtt tttatttccg ctaccgacta caccaagaca aagtttatga
     7561 ttgtcttcat gttccagata ttcacgcatc gtttcggtca agatttctgt atcaccgtta
     7621 tctaaaccat ttccgccgtc taaataagta ggaacgaaag taaaaaatgg ttctgtttct
     7681 ttcgtaaaat cactattttc atggatttct tttaaagtaa cttcaggatt gacaggatct
     7741 tctgcatgca ttttttcagc atattctgct agatgtttgg caaaggcacg cgtatttcct
     7801 gaaatcgata tatataaaat gttcatggat catcctccaa ttctttcctt ttagtatagc
     7861 atctttttta agttttttgg tggtgtaatt tggaaaggga ctaggcgctt tgcttgtata
     7921 atgagaaaaa agccggtaga attatatttc tattaaagtt tttattaatt aagtaaaaat
     7981 aaaaaaggtt tgttatactt tttgataaaa gcggttttat tttggaggat gcttacatgg
     8041 atacagagca acagaaaaaa ggaattggtt taattccact tgctgcctta gtaattggtt
     8101 cagcgattgg aggtggcgta tttggtatta tgacggacat ctccggatcg gctggcggcc
     8161 cagctatttt cagttgggta ctcgtaggaa cagcaatgtt gatgctctcc ttgtcgatca
     8221 ataatatcaa taaaaaacgt ccagatttaa aaggcgggat ctttagttac gcagaagaag
     8281 gttttggccg tttcgctggt tttatcagcg gttggggtta ctggctcaca tgctggttag
     8341 gcaacgtagc ttttgcaaca ttgttgatga gcgcattagg atatttcttc ccagtatttg
     8401 aaggtgggca aaatctggca tcgatcgtga tgagtacagt ctttttatgg ggatatgcat
     8461 ggctagtgaa tcggggagtc gaaaatgcta gtttcgtcaa tgctatcgtc acattctgta
     8521 aattagtgcc attattttta tttattgtag tagctatcag cacgttttcg atccaacaat
     8581 tcattgataa cttttctagc gacattatat tgaatgcgaa tggacagccg atcccgtttt
     8641 ccagtcaagt attgagttgc atcatggtga tgctttgggt atttgttggt attgaaggag
     8701 cctctgtcgt aggttcacga gcaaaaaaac aatcagatgt tgggaaagca acgattctag
     8761 ggatattcgg cttgattatt atttacgtct tggtttccat gcttccatat gggacaatga
     8821 cgatgaatca gctgcaaacg atcaaggcgc agcctgctat gggctatgtg tttgaaatga
     8881 tggttggtaa atggggagca gtcgtgatca acggcggttt gatcatttct ttagttggtg
     8941 tttggctctc atggacgatc ttaccgattg aaacaatggg aaacatggct gaagacggac
     9001 ttttgcctaa agcatgggga aaactcaaca aaaatggggc accaacttat gctatcgtat
     9061 tgacgacgtt atgtacgaat gtctttttac tttcattatt attcactgac agtgcttata
     9121 actttgctta cacacttggt acagcagcta ttttcttcac gtggcttttc ttaggattgt
     9181 accaaatgaa actttcttat cagcggaaag aatgggtcca atttttagta gggcttttag
     9241 caagtgcctt tcaagtatgg gctatgctag tcgtagcctt taatgaagta atgcttgttc
     9301 ttgttctttt cttgccaggc atttattttt acctcaaagc acgtaaggag caaaacgagc
     9361 ctgtacaaca tatccactta gataagattt tacttatagg tgtgacgatg gtcggagtga
     9421 ttgcaatggt tttatttgcc actgggatgc ttcacgtata gaagtataaa agaagtataa
     9481 agagaggttg tgagcctgtc gtttattcaa aaacatacta ggaaaggagc tgtgacacaa
     9541 atgttgtcac agctcctttt tcagaataaa cggtgtttaa gagacagcca atcggcaata
     9601 aggctgaacg tctctttcac agcctctttt ttgatgagtc atcatacatt ttttcgctta
     9661 aatacgagat atcctaatgc taagaacaaa acgatgtaag ctaaattacc gaatagcatt
     9721 tgattagtag aaagatgagt caattgcttc atgatctctt cgtttccaat ttggttttgc
     9781 agattcaaca tactgatcgg attccatttg atccactccc atttttggat gagtgcaata
     9841 aggataccag atatgattga cgaagcaaaa taaaagacga ttcctgctga gatggatgcg
     9901 ccggaactat tgataaagca agcaatcatc aacactaaac ttaaaatcag ccataaaccg
     9961 atataactac ccaaagtata agtgaacaag ctttggatca gtgtttgacc agtagaaacc
    10021 ttctccgtga aggaaatcga agggaaaaga atcagtttca tcaacacagt gacaataata
    10081 gctaaaaggt ataaataaac agaataaata actaatgtga tccatttgct tactaatatt
    10141 tctcctcgag aatactttcg ataaaggaga tttttcaatg taccatattg tgcttccatc
    10201 gaaatgatcg tgcttgcagc tgcaatcatg ataaagacaa tccaagatgt ggcactaaaa
    10261 agctgagcag tcatttcaac tggatcaatg atcgtcgtgt attttttggc tagaagtgct
    10321 gttcctatga gcaaaacaac taatagaaca gataaaacag cagttgactt tttcttgatc
    10381 aatttaaata attcttgttt tacaagcaat gtcatttttc ttcttccccc tttactgaat
    10441 ccagaatttc caatagagaa gattccaaat cattcgtcag atgctggacg tctgtcacat
    10501 ggatattttg tgcagacaat agctggatca cggttcctaa taattcttcg ttttctttta
    10561 aaagcttgat tttatcagga tcttccaaag tatatccagc ttctgtcaag atcgttcgag
    10621 cagctagatc atttgttgta gagataacga tgaaatcttg cgctgtttgg ttcaattcag
    10681 ccattgtaca ttgtttgatg atctttcctt gattgatcag gatcagctca tcgaccattt
    10741 tttcaagctc gctgagtaag tgactggaga tcaagaaaga ggtgccctga gtagccaagt
    10801 cggtaatgat ttttcgcaca tctcttgttg cttgtggatc caaaccgttc atcggctcat
    10861 ctaaaataac gatagacgga tggttcagta aggcaagagc aattcccaat ttttgtttca
    10921 ttcccaacga gtaggatttc gcttttttgt gaatgtactt ttccatcttg agctgattca
    10981 cgatagtgtc gatagcagat acatcgttgg tttcagagaa taacttcaga tgatcatagc
    11041 ctgttaagaa tggatagata cccgggtatt cgatcaatgc tcctacttgt tccaaccctt
    11101 tatgactaga gggagaaatc tcattttcac caatacagat tgttccatct gagtaatgga
    11161 tcagtcctaa aatagctttc atgatcgttg tttttccagc gccattagga cctactaatc
    11221 caacgatttt gccaggggat aagctaaaac tgacatcgct gagggcttgt ttgtgaccaa
    11281 agttcttgga taattcttgg accgaaagac ttttcaaaaa tattcactcc ttttctatag
    11341 atagtacaag catacacctg atgagtggag aagtcgctag gtcattggac ttatttctta
    11401 ttttttcata aaaaaattga atattaaata aaaaggctta ttttttctga tcagtactta
    11461 ttccaagtgt ctagtggccg ctagtaatct tgatgccaat gatactgatg agtagcatcc
    11521 ccacaaagaa ccaagtggaa agattcagct tatcatgaaa caagaccaca ccaattatga
    11581 ccgaaccaac tgcgccaatc cctgtccaga taggataaga gagactcatc ggcaaacttt
    11641 tgattgcctt tgacaaaaag taaaaactag caatcatgcc aatcactgtg taaaaagaat
    11701 aattgatttt agaaaaacca tcactccatt tcatcatcgt tgaccagaat acttccaaaa
    11761 ttcctgctat gattaattcc atccatgcca tacttacatt cctccttaac tataaaaaaa
    11821 tacacaaaaa gaggaaaatc atcccttcaa agacctaatg gaatgatcat cctctttatc
    11881 ctacccggtg gcagattgta tatctttttc tgtagtatag cacacctatc cagatatcgg
    11941 caatctcata ctttttagta aagtgtacca agcactgacg gatatatcgt tagcggaaaa
    12001 gaagatgaat gctttgcaat ttcatagaaa gaagttgtta tttattaatc atttaaaaaa
    12061 aacagtaact agaccttatt tctatatatt atcgggcaat aaattaaaaa aagctttacc
    12121 ttacaataag taagataatt tttgtgataa aaaaataacg aaaaatattt aaaaatagtg
    12181 tctatttcgt gagaaaacaa ctatattttt tatgtgtttt gctttataat taaaaaaata
    12241 ttgtcatttt atggaggaaa atatatggaa aattatctta gccttttagg cgtcttgatt
    12301 gttattctcg ggtttgcatt taaattagac tcgatattga tcgtaatggt tgctttagtt
    12361 gttacagctt tgactggcgg tcttggcatt caaggaatgt tagaactttt aggtacaagt
    12421 tttgtaaaca atcgcgggat ggcgattttt atcatcatta tgttggcaac aggaacgctt
    12481 gaaagaaatg gtctgaaaga atcagcggct tccttgatca agcgattcaa gaaagtatct
    12541 gctggtatga ttgtagatat ttatgggatc tttcgaatga tctttgcggc ttttaacgtg
    12601 agttttggtg gagttgctgg atttgttcgt ccaatcattt taccgatggc attggggacc
    12661 atcgaatcaa aagggttaga agtccatcct aagcatgaag aagaactaaa aggtatggct
    12721 tcagctatgg aaaatgtctg ctggttcttt ggccaagtac tattcatcgg aggagcaggg
    12781 gcgttgctag tccaatcaac actgaaagat ctaggatatg acgtaacatt gggacagctt
    12841 gctttagtgg aagttccagt ggctatcacg gctttagttg tggcaagtgt ctacttctat
    12901 cttaaagaaa agaaattagc gaagaaatat tatccaggaa aggggcaata agatggactt
    12961 ttttacaaat cctgatattt tattaggcga taaattactg gagatccttt atatcgtgat
    13021 gggactcgta ttgatttaca ctggagtaag aaatttaaca gataaaacca atcctcatcg
    13081 ttatgggtca gcctttttct ggacggtctt aggggtagtt attgcaggag gaagatggct
    13141 tccggcaatc gtgaacggtg gcttgatctt tgcgatgacc ataccagcaa ttgctaagaa
    13201 agtcagcaaa ggagaaagcc ggcttccatc aaaagaatat atggaaaaaa tgtcagacaa
    13261 actaggaatg aaaattttta ttccagcttt gagtatcggt gtctttgcga tcttgtttgc
    13321 tctatttacc aatttaggtg ctttagtcgg cgtgggcgtc ggtgtttttg cagccatgct
    13381 aatcttgatg ttcttttctc gagataatcg accaagtaca tttttagatg atgcagcaga
    13441 tatgctgggc acagtagggc cgttaagcat gttgccaatg cttttagctt ctctaggtgc
    13501 ggtatttaca agcgctggag ttgggacagt gatttccaat gcagtaggta cgatcgttcc
    13561 agaaggaaat gtgaacatcg gcatcatcat ttacgctctt ggcatggtga tatttacggt
    13621 aatcatgggg aatgcatttg cggccatcac cgtgatgacg gttgggatcg gtgcaccatt
    13681 cgtatttagt catggagcga atccagcgtt aataggaatg gttgcattga cttgcggttt
    13741 ttgtgggacc ctgctgacac cgatggctgc taacttcaat atcgtgcctg tagcgatgct
    13801 ggagatgaaa gacaaatacg gagtgatcaa aaaccagttg tttattgcgt tatttatgct
    13861 agttttccaa attgcttata tgattctatt taaataatag aagagagggg ttgtgacaga
    13921 ataattgtcg caacctcttc taacattgta gtggaacact atttttttat aagaatatat
    13981 taagtttgat ctgttatgtt atttaaacta ttgtttcctt tatttacgct gttcaaggaa
    14041 aatggtatga taaaagataa ccatatgtta aatcaatcgg acggaggaac aacagatgaa
    14101 agtactagta acaggttttg atccatttgg tggggacaaa gtgaatccag cctatgaagc
    14161 agtaaaaaaa atgccagatg aaatcagcgg tgctgaaatc atcaaagtgg aagtaccgac
    14221 cgtattcgaa aaaagcagtc aagtagtcaa agaagccatc caacagcacc aaccagatgt
    14281 cgtgatctgt gtcggacaag caggtgggcg gtcagcagtc tcgttcgaac gtgtcgcaat
    14341 caatctagca gaagcaagaa tccctgataa tgaaggaaat cagccattcg atacggcttt
    14401 agaagaaaac ggtccagccg cttactttac ctcattgcca atcaaagcaa tgacaaaaaa
    14461 tgtacaagat catggtctac cagcgtacat ctcttataca gcaggaacat ttgtctgcaa
    14521 tgatatcatg tatcgtttgc ttcatttgat cgaaacacaa ttcccggcaa ttcgaggtgg
    14581 gttcatccac gtgccattct cacccgatca agtgatcgat cgtccagtgg gtacgccttc
    14641 tatgtcttta gaagacattg cttcttcttt gacttatgca gttgaagcag cagtagaaaa
    14701 taaagaagat atttccggaa atgccggaac aactcactaa tttagcaaga aacactggct
    14761 ggttgctaac gttatgttag tagccagctt tttgtaatta gaaaggaaag aaacagccgt
    14821 ggaagaatgg caatccgtct ttgaagaatg gtttccaaaa gaaatcagca aaagctatcc
    14881 catcaaaatt tctaaacaat acacaagcag tcaacgttgg gagatctatg caaaattaac
    14941 gaaaaaacag cgggaactag tcgataagca ccgccgatat ctaatcagct ctcgttttat
    15001 ggaagaacat tatttagctg caacagattg ggtgttttct gacttcaaga tcaatccgtt
    15061 ttttcgaaca aaacgaagcc agcaaaaatt gtattgtgag tgtggtagag aattaaaagt
    15121 gcaatacatc gttaaatcgc caaaaaccgg aaagatccta aaactaggca tcaaccactt
    15181 tgccgatcac ctgcatgtct ctccgacagt ggcagcttcg atccatcagg gaatgacaaa
    15241 agttgatctg gccttagacg aattattatg gcttaagcag aagaatatcg attttcctga
    15301 aggactatgg caaaaatact gttttgtctt gtaccaaaat cgtcggatga aacagccata
    15361 tttaccggat ataaaattag ctcagcggct cgcagaattt cgccaagtag aaatgccgat
    15421 ttacatagcg gattatcaag cattggaaaa tgaaatcaag aaaataagtg aacacatcaa
    15481 tgggcagtca aaaaagcgac agataaaaaa agaactattt gacgactttg cagaagaatt
    15541 agtaaaggat gtagaagaat tcttgatcaa ctatcgcgca tttttacgta aagattggca
    15601 atccatcgta tatgaagaag tgccagtaca tcctaatgct tattttgaaa catttatttc
    15661 cgtgttgaga aagacaaaac gtcaacgaac accagaagtc actgctcaga tggaatattt
    15721 tgcgaaaaac caacgattca tccaaccaaa aatctatcta tttatttgga agcaatattg
    15781 tcgctatggt tttacagaag ggttcttcga cagcattcct cggatagtca gaaatggttt
    15841 tttaaaagta ttgcgtaaag aacgagaagc tatacaatct gctgataaga aagaccgtac
    15901 agtctcaaaa gaaaaatggc aactagtagt gaaagatatc caatctggaa atgtgcaaga
    15961 gacaatcgac aaatggaaag gaaaacatta tcgttttact gaagctcaga aacaagcgtt
    16021 ggaatattat cagaagttag aagaatcact gcgtttcaat gatgaggcaa gaaagtatct
    16081 gaaggaatta ctataaaaaa catactaaga ttagagggga acatcattga cgaatgatgt
    16141 tctcctctat tttctatttt tagattatag tgaagagtga aagaaagttc gaacaaagcc
    16201 ttgaggacta cgagtcccta tcaaaaaccg aacttcttta ctgtcatttt agaatcaggt
    16261 ttacgtatgt tggggccatg agcccgtgta taggaaattg gaatcgaaat gaagcagtaa
    16321 agttctttca aaacttaaaa aggaggaaaa caaatgcctt acattcttgc attagatgtt
    16381 tcaatgggac acagctacag tgtcctatac aaagacgaca cctgcttatt tgaagacgag
    16441 attgaacaca ctcaaagagg atttcatgca ttactcgaag agatccagca cttgcctgag
    16501 cgtccattga ttgtttttga agcaacgggg atttattcca gaccagtcga aaagttcttt
    16561 caagatcatc acttttctta ctgtttgtta aacccgttag aggcgaaaaa acagatggaa
    16621 gaaagcacct tacgcagttg gaaaacagat aaatcggatg cccaccggct cgcacagact
    16681 catcttaaaa atcaacgtca gccaaaagaa gtacaaagca atttttactt agagatgcgc
    16741 gatttagccc gtttttatca agaaattgag aagaaaatca ctcgtctgcg catggattta
    16801 cacaactgcc ttcaattgac ttttccagag cttgaacagt tcttttcaaa caggctgacc
    16861 ccttacgcat tgacattgat ccgtcttttt ccccatccag attttgtatt ggcatctact
    16921 cggacaaaaa taaaaaataa actgatcaac gaaacacgga aaaaaatctc cgcgaatcgt
    16981 gccgagcaaa aggcagatca aatcatccac tatgcacagt gtgcctatcc agctgttgaa
    17041 aaagacagta tccactgtca aaaaacgatc tattacgccg aacttctcca agatttactc
    17101 gaacaaaaaa aagcactggc gacacaaatg atcaaaaaag ccgaaggctc tccttgcttt
    17161 ttgttgtacc aaacgttccc tgggattggc gcactcacag ccgctttatt gctcggtgaa
    17221 ttaggagata tcacacgatt taaaacccat aaacaattga atgcctttgt cggaatcgac
    17281 atccgacggt atcattcagg taagtatact ggccaagacc gcatcaataa gcgtggtaat
    17341 cccaaagcac ggaaaattat tttcttcacc attcgaaata tgattcgcca gcaacgcgca
    17401 gctcctaatc atattgtcga ttattactac aaattaaaaa agcaacctat ccctaagaaa
    17461 gataaggttg ccacagttgc ttgtatgaac aagcttctga aatgtatgca cgctatggtt
    17521 agggcacata cagagtacga ctatgcgtac gcggtctcag tggaccatta actaaaccac
    17581 ttacagtata ccacttcttt gcccagatcg aaaatttttt acgaacgggg ctttatttgg
    17641 tgtgctttga ttttgtcgct ttcgtttacg agctattttt cttgcacctt ttacttgact
    17701 aatcgtagga aatagaggct gggacagaag cgtttaactc caagaaataa gaa
//
LOCUS       DADLIO010000225        16411 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.guided.055, whole genome shotgun sequence.
ACCESSION   DADLIO010000225 DADLIO010000000
VERSION     DADLIO010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16411
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.guided.055"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            144..1403
                     /locus_tag="JOX41_002993"
     CDS             144..1403
                     /locus_tag="JOX41_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAY6450650.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            1409..1990
                     /locus_tag="JOX41_002994"
     CDS             1409..1990
                     /locus_tag="JOX41_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IDEAL domain-containing protein"
                     /protein_id="HAY6450651.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(2072..2947)
                     /locus_tag="JOX41_002995"
     CDS             complement(2072..2947)
                     /locus_tag="JOX41_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAY6450652.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            3095..3427
                     /locus_tag="JOX41_002996"
     CDS             3095..3427
                     /locus_tag="JOX41_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAY6450653.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            3539..4747
                     /locus_tag="JOX41_002997"
     CDS             3539..4747
                     /locus_tag="JOX41_002997"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HAY6450654.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            4901..5356
                     /locus_tag="JOX41_002998"
     CDS             4901..5356
                     /locus_tag="JOX41_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450655.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            5718..5993
                     /locus_tag="JOX41_002999"
     CDS             5718..5993
                     /locus_tag="JOX41_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450656.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            6006..8084
                     /locus_tag="JOX41_003000"
     CDS             6006..8084
                     /locus_tag="JOX41_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAY6450657.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            8244..10130
                     /locus_tag="JOX41_003001"
     CDS             8244..10130
                     /locus_tag="JOX41_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAY6450658.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            10142..11089
                     /locus_tag="JOX41_003002"
     CDS             10142..11089
                     /locus_tag="JOX41_003002"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAY6450659.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            11109..11636
                     /locus_tag="JOX41_003003"
     CDS             11109..11636
                     /locus_tag="JOX41_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAY6450660.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(11699..12352)
                     /locus_tag="JOX41_003004"
     CDS             complement(11699..12352)
                     /locus_tag="JOX41_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HAY6450661.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            12484..13326
                     /locus_tag="JOX41_003005"
     CDS             12484..13326
                     /locus_tag="JOX41_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAY6450662.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            13484..14380
                     /locus_tag="JOX41_003006"
     CDS             13484..14380
                     /locus_tag="JOX41_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAY6450663.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            14383..15096
                     /locus_tag="JOX41_003007"
     CDS             14383..15096
                     /locus_tag="JOX41_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HAY6450664.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            15116..15634
                     /gene="msrA"
                     /locus_tag="JOX41_003008"
     CDS             15116..15634
                     /gene="msrA"
                     /locus_tag="JOX41_003008"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAY6450665.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            15631..15858
                     /locus_tag="JOX41_003009"
     CDS             15631..15858
                     /locus_tag="JOX41_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HAY6450666.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            16010..>16411
                     /gene="lepB"
                     /locus_tag="JOX41_003010"
     CDS             16010..>16411
                     /gene="lepB"
                     /locus_tag="JOX41_003010"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAY6450667.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQS"
BASE COUNT         5707 a         2777 c         3402 g         4525 t
ORIGIN      
        1 ttttttggca gaaaaaagca aaaaaatact tgttttagaa aaaataggta taatagacgg
       61 ataccaacat ccaaacgaaa aagaattatt gagaacaatg acggtatttc aacaaatcgt
      121 cagtgagata agagggaatt gaaatgaata caaatagcga aaaaatgttg caagctttat
      181 cagatgaaga cttgtcacaa gcacaaatct ttttagaaaa agcattaaaa gaagacccag
      241 cagatatatt agctgaacta ggcgaagaat tgctggctat tggctttttg atcgaagcaa
      301 aacagatttt tgaacaactg atcaaccaat acccagaaaa tgacggactg aacatcccgt
      361 tagcagaaat tgcaatcgaa gataatgaga tcgacttagc ttttgaatac ctggaaaaag
      421 tggataagca aagtgattac tatccgcaaa gcttattggc gatagctgat ttgtaccaag
      481 ttatcggaat ccctgaagtg agtgaagcaa aattgaaaga agcagctggg ttgcttcctg
      541 atgaaccatt gatccagttt gcgctagctg aattgtattt ttcagttgat cgtttcaaag
      601 aggcagcagt ggtttatgaa acattgttgg caagcgggat aaatgaaatt tcaggaatct
      661 cgatgcagga acgtttagga caatccttaa gtatgcaagg agaattcgaa gcagctatcg
      721 tacctttaga agaagcactg aaagaagaaa ggacagatga tcgactgttc cagctagctt
      781 ttacgaatct tcaattgaaa gaaaatcagc aggcaatcaa ctatctggaa gaacttcgag
      841 aagttaatcc gcattatcaa tcgttatatc tatatctagg acaagctctt caagaagaag
      901 aaatgattga agaagcacaa acagtgttag aagaaggaat caaagaaaat ccttaccaag
      961 tcgaacttta tcacctggcc tcggaaaatg ctttccgtct gcatgataga cagcgagcag
     1021 aagaactttt actgaaagct ttagaagtag gagacaaaca agatgaaaca ttacttactt
     1081 taagtaatct ttacttggat gatgaaagat atgaagatgt gatacaagtg atcaatcaga
     1141 tggaagaaac tgctaatcct tatgcagaat ggaacctagc ccatgcttat aatgaattag
     1201 aagactttac cgttgcagct gtacactatg aacaggctta tcatgaacta tcacatgaac
     1261 cagatttctt gaaagagtat gcctttttct taagagaaga agggcagctg aaaagagcgc
     1321 aagaattatt gacttattat ttaacacttg aaccaggaga tatggaggca ctgtcattat
     1381 tagatgacct aacagagagg tgagaaaaat gctaattgat gtacgggaaa agaagaattt
     1441 tttaacgtgg atggtcaatc atgtatcttt tagccgaaga gaagtttttt ggatcttgaa
     1501 ttatcttgcc aatcatgaag cgattttaag caatgtccac tttgttgaag gggcgaattt
     1561 tgcggatcga ggactgcaga tcagtgatct atctgttgaa ggggaaccca tgaaattgtt
     1621 tttgcaggga aaagaattta cggacacaga ccagattttt catgaaatcc gtttgaattg
     1681 gaaaaagcct ttatatgtgg aatgtatatt cgaaaatgct tggcagacaa gagaatatct
     1741 atctatctta gaagacaatc cattttcttc ttgggattct tcagtcagtg aagaagatac
     1801 tgaattaatt gaacgatatt ttcaagaaaa agaagaagag gcaaaactaa aaatgcttta
     1861 tgctcaaatc gatcaagcac tagaagatgg agatagggat gcttttttga aattatctga
     1921 tgaagttaac cgaaagatcc ttttgcagac acaaaagaaa agtaaccggg taagtgaaca
     1981 taacaattag ttaaaaatag tatagtacta aaaaagacaa aggtcagctg gatgtggaat
     2041 ctttcctcat agcctatctt tgtctttttt cttatagttt tttcagtaat cttgtctgtg
     2101 gcttcaaata agtaaagcct tgcccttcca cttcatgcac attgatgatt gaaaggaaag
     2161 ctttttcgtc aatctcgtgg acgatcctct tagcttcagt taattcacta gagctaacga
     2221 ccatatagat gatttttttt gaattaccag agaatgcgcc ttctccagaa aggaaagtca
     2281 cacctctttg cagaccggtc atcagtagtg gtgcaatctc ttcgcttttg ttggagacga
     2341 caagtagacc ttttgcagaa tatccgccat ctaagatcga atcaatcaca cgactgaaaa
     2401 catacgaaac aatcaacgta tacatcatac gtttcaagtc gatataggtt aatgaagcaa
     2461 gtaagacgat gatatcaaat gccaataggg aacgccccat agtgatgccg taattttgtt
     2521 ctaaaatccg agcgataata tcactgccgc ctgttgttcc acccatgcgg tagacgatcc
     2581 cgcttcctac acctgcaact aaacccgcaa gtagagaaac gatcagtaga tcatgctgta
     2641 aattgatttc tagtggaacc ctttgccaga tccataaaaa gaatgacaaa gaaagtgtac
     2701 ctagaacagt ataggccaag gaacgtttac cgaggatctt tcctcctagt aaaatcaatg
     2761 ggatgttgat taataaagtc gtataagctg gatcaatacc aaataaagct cttaagatca
     2821 aggtgatccc tgagactccc ccttctgcta aatgattagc gatgttcaag taaacaagac
     2881 caaatgcata aatacttgtt cctataatga taaaaagaac ttcttttact gtttttcgtt
     2941 tgaccatatg aattccagct ttcaattatg tattttcaca gaatttccat ttagaaattc
     3001 cttcctaaat gtagcatgga aattcgattt tctcaattgc tcttatctag gatttgcgtt
     3061 aaagttttgg taagatagtt ttggagggaa aaagatggat aaaaagcgtt ctttatacag
     3121 tatgcagcag gaagtggatg aatatatcca gcaattcaag gtggggtatt tctctccatt
     3181 agctcagatg gctcgattaa ctgaagaagt aggtgaattg gcaagagaag tcaaccacac
     3241 ttatggagaa aaaagcaaaa aggcttctga accagttaac tcggtagcag aagaacttgg
     3301 tgatgtttta ttcgttacga tgatcatggc taattcattg aatatcgact taactgaagt
     3361 ttttgaaaaa aacatggaaa aattcaatca aagagaccat aatcgctttg agcgtaagga
     3421 cgagtaaaca agatgaagtg gtcctggcct tgaagactct gaaacggact tgtcaaacag
     3481 tcaccatgca actgagtctt tatctcagga caagaaacac gcaggaaagg ttggaaaaat
     3541 gaaattaaaa caattacctc tggaatacca aaaggcaatt ccagttctga aaaaattaga
     3601 gaatgcagga tatgaagctt attttgtagg tggaagtgtt cgtgatatct tgctgaacca
     3661 gccaatccat gatgtggata tcgcaacaag cgcatttcca gaagaaatca aacagctttt
     3721 tccaaaaacg atagatattg ggatcgaaca tggaactgtg ttggtattag aaaatgatga
     3781 acaatatgag atcaccacat ttcggacgga atcaacttat caggactacc gtagaccaga
     3841 tcatgtcgaa ttcgttcgtt cgttggcaga agatttgaaa agaagagatt ttacgatcaa
     3901 tgcgtttgct ttgaaagaag atggagaaat catcgatttg ttcgatggtc tgcaagatct
     3961 agaagaacag atcttgcgag ctgtaggcaa tcctcatgag cggttccatg aagatgcctt
     4021 acgaatgatg cgcgggttgc gttttgtcag tcaactaggg ttcaaattag aggaagaaac
     4081 cttctacgcc atcaaagaaa accacgagct attaggtaaa atatctgtag aacgtataaa
     4141 tgtggaattc atcaagatgc tcttgggaaa tgaacgggcc gcgggaatcc atgcatttat
     4201 tgaaacagag tgctacattt gctgtcccgg tttgaaagaa gaaggcgaag cacttttacg
     4261 ttttgctgaa ttaccatccg tcccattgaa agaagagagc caagcatggg cattattgat
     4321 cagccaactg gatctaaaag aaaatgagat tcgttccttt ttgaaatcgt ggaagtgttc
     4381 taaccaaatg attaaagacg ttcaagcact tgtccaagga ctacgacaac gagaaactgg
     4441 agctttggaa ccattcgaat tgtacttctt aggcaaaaaa catgcactgc aagtagaaga
     4501 attgatgatc tattttgacg aaacacctca gatggatgcc gtaggagaat cctatgatcg
     4561 tttacctatc aagtcattaa gcgaattagc agtagatggt aaaatcttgc tagaagaaac
     4621 tggaaaaaaa cctggtaagt gggttagtga agctttgcaa ttagctgaaa aagccgtcgt
     4681 agaacaaaga ataaaaaatg ataaaaaaca ggttttggat tttttatcga aagaaaaatt
     4741 gatttaaaaa acactagact gtatctgctc agctttgttg gctacttaaa gtgggcagat
     4801 acgtcattag aagaaaaaac ataagatgtg accacttaca taaatttgtg ctaaactgag
     4861 gtagtacaag aataaattac atcataaagg agtcttttta atgagtaaag aaatgacagc
     4921 gctaaaattt tattttagaa atggagaaac ctggacgatc aaccgccgtc atatcggcga
     4981 tctttggatc aaacaaatca caacaagttt tggacgaatc aatggcagtg aatttgttga
     5041 aatccatccg tgtgctggat ttaaaatcga aatcttccat gaaggggacg cagttgcgac
     5101 acatgatatc aacctaggcg gactggaaat gggcatgttt aatcgcgcat tgaaatacga
     5161 agatatcgag cgaatggaaa tcctttaccg aaatggcaca cctgatcttg tgtacttccc
     5221 atatctagat aaaggaacag aaggattaga caatcaatat caatcaacaa aaatcagcga
     5281 aaaaacaggt aacttgtata tcgtgatcaa tccagatcaa cgtgtagaag atgtatacgg
     5341 ggaatttttc gaataaatcg atttttacgc aaaaatgagg ctgtgaaaga gatgtgtctt
     5401 attactactg ataggctgtc tcttccacac cgtttattca gaataaggga ctgtgacaag
     5461 atttttgtcg cagccccatt tttttgttgt gataaaagaa caagaaaggc aggaatggga
     5521 aagtaaacat ccttttgtca gaaactttta tctttcttaa gttttacttg atatctgata
     5581 ctatttggaa tagaatgagg cgttgaaaaa tttatggaaa tttctaacta gcaataaacg
     5641 atgaaacaat gaaatatttt tcatccaaaa agaactttgc tataatgatg gaagtttgtg
     5701 tataggagat ctggaaaatg agagagagtt ttgaacaaca aaaaaaactg ttgcatgatc
     5761 gctatggcgc cctttcgatg gatgaccgcc gtcaaatact ttgtaagttg cgtaaaagaa
     5821 atatattgat gtatcgtcag ttggaacgtc tgaaacatga tctgcttcgt ttggagtcaa
     5881 aacgtgtaca gtgtgaatta gaggggaacc aaacacaggt tgaagtagtc gaaaccaaaa
     5941 ttttaaagaa aaaagaacaa tttttaaaaa tgcttacaca aaataaaaaa taaaggggat
     6001 ggacgatgga atttgctgag ttagttattg tatttgcagt aacgatcacc ttatcgaaca
     6061 tagctagccg cattttgcca atgattccag ctccactgat ccaaattttc cttggagtgg
     6121 tattaggtct gacagagtgg ggacaatcaa tcgattttga acctgaattg ttcttagtta
     6181 tgattattgc accattgtta tttagagaag gagaaaaagc agatatttct tcgattctca
     6241 aaaatttcgg gacaattttg ttcttggcat ttggaggagt cattttgacc cttgtcgggg
     6301 taggtgcgac gttatcattc ctgttgccaa gtgtcccact tgctgcctgc tttgcttttg
     6361 gagcagcgtt aggtccgaca gatgcggtag cagtcagttc tctttctgga cgagtgaata
     6421 tccctaaaaa ggcgatgcat attttggaag gagaaggtct tttgaatgat gcatctggtg
     6481 ttactgcctt ccagtttgct cttggtgcgc tgatcaccgg atctttttca gcagtaaacg
     6541 cggggatgag tctagtagtt tctagtattg ggggagcttt gatcggcttt ttgcttgtct
     6601 ggttcaaaca aaaaataatt catttgatcg aaaaagcatc agcacaagat gtcacagggt
     6661 atctgctgat cgaacttttg cttccttttc tagcctatgt attggcagag gcatttgatg
     6721 tatctggaat cattgctgca gtggcagcag gtattctcca agcttctggt tttaggaaaa
     6781 tctctgtgtt tgatgcagaa ttgtcgagct tgtcccacag tacatggaca actattgctt
     6841 ttacactgaa tgcattagta tttatatttt taggaatcga attgacgcaa gtgttctcgc
     6901 cagtatgggg agacggttta tatccaaacg gtcttttatt agcgattatc gtattaatct
     6961 ctgtcatgct ttttgtgatc agattcattt ctatcagtct tttttatgta ttcaaagatg
     7021 gcagtaaaaa gttcaaaaaa cagttgaacg agatcttgat cttaacattt ggcggtgtaa
     7081 agggaacagt cagtttggct acgattttta ttttgccatt ttcaatcaat aatatgatgt
     7141 tttaccagcg gtctttgctt ttgtttctga cggcgggtgt catcttagtg actttggtca
     7201 tagggatcat tgtcttgcct atgctgacgg aaacagagga agcgaaaagc acggatttga
     7261 atgctttgat gattttagaa gaggtcgttg aagttttgcg aaaagaaata aaggaaattg
     7321 atcgtaatac aaaagaattt ttagccactg aagcagtgat agaaaattat caagaacgga
     7381 tacgtgatct gtacttggaa gatttaaccg atgatgaaaa gcaagaagta caagaaatac
     7441 aagcactgat tttgtcgatc gaacgggatg gattggatga aagttatcgt tcgggcaagc
     7501 tttcttctaa tggttatcgt ttttactccc gttttctttc tcgattcgaa cattctatca
     7561 caagccagat tttgtctttt atcggctttt ggttcattgt tgtccgtagg ttaatgcgaa
     7621 tcgttctcca tccgaaaatg ttttggcaaa gaagatatgc tgatcgtcag acatttatta
     7681 gtgatgaaga tatccaagaa atcagagaga catatcaaaa aaatactcag ttgattattg
     7741 aaagtttaga taacttgact gatatttatg atgaaacgat ggttcaattt tttatccagc
     7801 aacgcaaact tgaaggaata aaaatgaact cggggaattt gatttcttcg tggatgatcc
     7861 agcaagatag tctgtttacg aaaaaaatgc taagaggtta ttatcttgaa agaaaaatca
     7921 ttgatgaata cgaagttgct gaaaaaatca cgacgttttc tgcgaacagc tatcgcagga
     7981 atatcaattt gttagaatct tatacgatga acaaaccatc tgataacttt tctttccgat
     8041 ttgcgtttcg agcaaagtca aaaaaaacga gtccaataaa ataaaaaggt aaaaattttc
     8101 aagttttata aaaaacaaaa catatcagaa caggatcgaa tcggtcctgt tctttttttg
     8161 agaacacaaa aagaacaaat accaaaaaaa ttttcctgaa gttcactatt tttatgatac
     8221 aatatccaag ataaggaggg aacatgttga aagaattaaa agtaactgac ctcaaaaaaa
     8281 cttatggtga aaaagatttg tttgaccaga tttctttttt ggtccacgaa aaagaccgta
     8341 tcgggttgat tgggacgaac gggacgggta aaacaagtct cttaaatatt attgccggta
     8401 tcgatagcag cgacggtgat cggcaaacag tgttttatcc aactgattac cgtattggtt
     8461 atctttctca agcagctgaa ttttccgatg aattaactgt tctccaagca gtctttcaag
     8521 gaaacagccc cttgatccaa actgttcgag catatgagga agcattgatc gaactagggg
     8581 aaaacggaga agaccctgat gtgcaaaaac gttatgctaa agcagaagaa caaatgaata
     8641 aagaagatgc ttggactaca gataccaacg caaagattat tttgcaaaaa ttaggaatca
     8701 gtgaattaga taaaaaaatc agtactttat caggtggtca gaaaaaacga gttagtctgg
     8761 cgcaagtgtt gattgatgaa cccgatttac tattactaga cgaaccaaca aaccatttag
     8821 attatgaagc gatcgagtgg ttggaaaact atttgaaaca ataccgtggc gcactattga
     8881 tggttaccca cgatcgttat tttctagata gagtagcaaa ccgaatcttc gaactttcat
     8941 ttggaaaatt atacgagtat aaaggaaatt atgaagctta cgtcttagaa aaagcagaac
     9001 gtgatcgtgt agaagtagaa caagaagaaa agcgcaagcg gctttataaa caggaattag
     9061 cttggatgag ggctggcgta caggcacgtg gcaccaagca gcaagcacgg atcaaccgtt
     9121 tcgaagatct aaaggagaac ttgtaccaag taaaccaaga agatgattta gagctgaacc
     9181 tagcgacaca acgtttaggg aaaaaagtac tggaaatcaa agatggcagt taccgtataa
     9241 atgaccaaac actgctagaa catttagatt tattgattca atctcgggaa agactaggta
     9301 ttactggtaa aaatggtgcg ggaaaatcga cattgcttaa tattctagct ggcagaattc
     9361 ccctggatag cggtacaatg tctatcggtg aaacggttca tcttgcgtat tatacacaag
     9421 aaaatgaaga aatggcacca gataaacgga tgattgctta cttacaagaa gctgctgaag
     9481 aagcaaaaac agcagatggc agtcaaatcg gagtagcaga attacttgaa cgatttttat
     9541 ttccaagatt tatgcatggg acactgatag gcaaactttc aggcggagaa aaacgccggt
     9601 tatttttgtt gaaactgctg attcagcaac ctaatgtttt attattggat gaaccgacca
     9661 atgatttgga catagcaaca ttgacgattt tggaagatta ttttagaagt tttccaggtg
     9721 ctgtgatcac tgtttcccat gaccgttatt tcttggacaa ggtagcagat aagttattag
     9781 tattccaagg aaacggaaaa caagaacttt attacggaaa catgtccagt tatttactga
     9841 agcaaaaaga gacccagcag cctgctgaaa aagcgaaacc aaaaatacag agcaaggaac
     9901 ctgctgaaaa gaagaaatta tcttacatgg aacaaaaaga atgggaaacg attgaagatg
     9961 agattgcaga acttgaagaa aaaatctcat tgctccaaga agagatgaat catcaaggag
    10021 ataatttcac tcgattacaa gaattgcaaa acgacgtatc tgaaacagaa gcacaacttg
    10081 aagaaaaaat ggcacggtgg gaatacttga gtgaatgggt agaagattag gaggaaaaag
    10141 gatggaacaa gcgtatcttg acttaggaag aaaattgttg gaagaagggc atcgtaaaga
    10201 agacagaaca ggcacaggca cattaagctt attcggatac caaatgcggt ttgatctgca
    10261 aaaagggttt cctttgttaa caacgaaacg agtacctttt ggattgatca aaagcgaatt
    10321 gctttggttt ttaaaaggag atacgaatat ccgctatcta ttacaaaata aaaaccatat
    10381 ttgggatgaa tgggcatttg aacgctacat caaaagtcca gactataatg gaccagatat
    10441 gactgatttt ggccatagat gtttgacaga tcctgaattc aatgaagaat ataaaaagca
    10501 gagcaagctt ttttgcgaga agatcctaac cgatgattcc tttgctgaaa catacggcga
    10561 tcttggacac atctacggct atcaatggcg tcactgggaa acaaaagacg gtggctttat
    10621 cgatcaaatc aaacaagtga tcgaagcaat caaaaagact cctgattcta gaagattgat
    10681 cgtttctgca tggaatccgg aagatgttcc tagcatggct ttgcctcctt gtcatacgat
    10741 gtttcaattt tatgttcaag agggacggct aagctgccaa ttgtatcaac gcagtgggga
    10801 tgtgtttcta ggcgttccgt tcaacattgc aagttatgcg ttgctgactc acctaattgc
    10861 acatgaaaca ggtttagcgg ttggcgaatt tgttcacaca ttaggagatg ctcatcttta
    10921 tatcaatcat atcgaacaaa tgaaagaaca attgagccga gaaatacgcg catttccgac
    10981 tttagttttg aatcaggaaa agcagtcagt atttgatttt gagatggaag atatccaatt
    11041 agaaggatat gacccacatc cggcgatcaa agctcctatc gctgtttaga atcagaaagg
    11101 atgagaaaat gttagctgca atttgggcac aggatgaaaa cggattgatt ggaaaagaag
    11161 accgtcttcc ttggcgtttg ccaaatgatc tgaaattctt caaacaaatg acagaagcaa
    11221 atacactagt gatgggacga aaaacattcg aagggatggg tagccgtccg ttgccgaatc
    11281 gtcagacgat tgttttgacg agagattctt cctataaagc agaaggcgtg catgtcatgc
    11341 atagtgtgga agacgtgctt gctctggaaa aagaaacaga cggtatcttt ttcatcgctg
    11401 gagggtcagc tgtttatcaa gaatttctgc cattttgtac gatattatac cgtacagtca
    11461 tccatcatgt attcgatgga gatgcttatt ttccacctgt tgactggtct gattggtcac
    11521 tgatcaatac tagtcaagga gaaatggatg aaaaaaatcg ttatccgcat caatttgaaa
    11581 cgtatcagcg taatgagaat cctgtaaaaa gcgggacagg cgaattgacg atataaaaaa
    11641 gctatggata gactagctgt tatttagagc tgtcccatcc atagctttat tttttttatt
    11701 aagtaaagaa taaaacagag aagtacataa aacctgcacc taacataaca aacaaatgcc
    11761 aaacaacatg catatagcgg atagaattca agctataaaa gaatgcgcct atcgtgtaag
    11821 aaagcccgcc tgctaccatc aaaataacac cagtcattcc aagagagtga taaagaggaa
    11881 cagcagccac gacacagagc caccccataa aaatatagat gatcgtagat acttttgata
    11941 ctctctcccg tttatgcaac gtcaacgctt tatatataat gccaagaatc gcaaacaacc
    12001 agattaatac aaataaagtc caacctagcc atcctcggat actcagcaaa caaaaaggag
    12061 tataacttcc tgcaatcaaa agaaaaatcg aactatgatc gaatacttgg aacacctttt
    12121 ttgcttttgt aaaaatcaat gaatgaaaca aagtagacgt taaaaataaa agaatcatca
    12181 tcgatccata gatagcataa gagacaatat ggagggagga atgcaagtgg gcacctttta
    12241 ctaaaagaac cactagtccc gcgatactca atccagtccc aattccatgg gtgactgcat
    12301 taaacacttc atttaatatt tcatacgttc gattaaattt cgttttttcc atgaaaacgg
    12361 ctcctttact aggtgtaatt aatgaaaaat cattatttgt ctgttatact aaaaatagaa
    12421 attgtcttac atgtagttta acatgaataa ggcatcttgt taaagaaaga gagagagaaa
    12481 ataatgacaa atgtaaaaat cgtaacagat tcttcatgta cgatggaaaa aaatgtacgc
    12541 gatgctttag gcattcgtgt catgccgcta tccatcatga tcgacggaac agtatatccc
    12601 gatgatgacc aactagacgg cgaaagattt atggaaatga tggcgaaagc aaaaaatctg
    12661 cccaaaacaa gccaaccacc aattggagaa ttcatctcga tgtatgatga gctaggagaa
    12721 gacggcagtg aagtgatttc gatccatatg acaaaaggct tgagtggaac agtagaagca
    12781 gcaagacaag ccagtaatct aacaaaaacg aaagtaacgg ttatcgacag tgataccact
    12841 gaccaaggat tatcttttca ggtaattcga gcagctgaat tagcaaaaga aggtaaaaca
    12901 gtagagaaaa tccttgaaga agtcaaaaaa gtacaagaca atacaaaatt atacatcgga
    12961 atatccacac tagataactt ggtaaaaggt ggaagaatca gccgaacaac tggtttgctg
    13021 tctagtgttt tgaacatacg cgtggtgatg aatttcgccc attctgaatt aatccctgta
    13081 actaaggggc gaggaaagaa aacgttcgat aaatggttta ataatttgaa aaatgaactg
    13141 aaagaattgc caaatgtgcg acaaatcggt atttcacatg cggatgcaaa agaattggcg
    13201 caagaattca aagagggttt gcaagaatta ttcccggaca tgcatatccc tgtactgcat
    13261 acgaatccgg ttatcgctac gcatactggt aaagacgcgt ttgcaatcat gtattatgta
    13321 gattagtcga aaagaggata agccctcagc ctgaaaggct tgcagcttat tctctttttc
    13381 tttataaaat taggaaaata attgttttct tttttcataa agactacctt tttgataaaa
    13441 tttttgataa cattagaacc aatcgaatac aagaggtgaa aaaatgaaat taacgaaacg
    13501 acatttgatc ctcgttttgt tcccattatt aattgcgatc atcatctatg caggtttagc
    13561 tgcttctata ccgaaagctg gcccactaat gaaaccagta actactgtga gagaagatcc
    13621 aaataaaaaa gaaaaacttc actacatagc tatcggagat tcgctgactg aaggagtagg
    13681 agatcaaacc aagcaaggag gattcgttcc ccttgtcgca aatgatctaa aagaccgtta
    13741 taatttgacc gcggttgaaa cagaaaacta tggtgtaaat ggtgaacgaa gtgaccagat
    13801 cttaaagcga gtaaaaacaa aagaagaaat tcgaaacaat atcaaaacag ctgattttat
    13861 cacactgact gttggcggta atgatttgat gaaagttatc caaaataatt tattcgggtt
    13921 aacggtcaat tcctttaaaa agccactgaa aaactatcag gaaaatgtca cagaactatt
    13981 ggaagaattt cgatccctca ataaaaccgc acctatttac attttaggca tctacaatcc
    14041 attttatttg aactttcctg agatcactga catgcagaca attgttaaca attggaacaa
    14101 aggaacagaa acggtgacaa aaaaaatgcc gaactgctac tttatcccaa tcaatgattt
    14161 gctttatcaa ggattgaatc aggaagtagg tgtcacagaa gaaggaacag atcaaacaac
    14221 tagcacgaca gaaaatctaa atggcatcaa aaataatgtg ctctatgaag aagatcattt
    14281 ccatccaaat aatttaggtt atcaattgat ggcaaatgca gtgagagatc agctgatcga
    14341 gacacaaaac caatggttag agaaggagga tgatcaataa acatgaaaac aagatctgac
    14401 gtatcttcaa acaaaacaaa gaaaacaaat tactggaaat tcgccttcct tatccttctt
    14461 ggggtagtac ttggttcgac cgtattttta ggcagccgta tttttgctaa tcgggaacca
    14521 gaactcccag aaataccagc tcttacggaa agacaaggag atcctgtctt aacgatcaat
    14581 tcaaataaag aaaaagtcaa tcaaatcatc agctttttcc ttagtgagta tcaaaaagat
    14641 agtgatattg aatataaatt ttatttggaa aatgaagcac tactcaatgg tactttcgaa
    14701 gtactaggtt ttcctatcga tttctattta tattttgatc cgtatgtgat ggaaaacgga
    14761 aatgtccaac taaaagctag aagtctttct atcggaacat tgagtttgcc aatcaaagat
    14821 gtgatgaata tgatcaagag aaactataaa ttaccagatt ggatcgaagt caatacagat
    14881 gatctgacta tcatgcttag gttggatcaa ttccgaatgc aaaacgggat gtatattaaa
    14941 gcagataaaa tcgacttagt aaatgatgac attcggttta gtctatattt gccaaaagat
    15001 acctctgatg cttcaaacaa ctcaaatacc aacaaaacta gcaccagcag tactgaaagc
    15061 aagacaaaag aaaataaaaa atcatcggat gagtagtatt agagggggaa tcataatgga
    15121 acgagcaata tttgcaggag gctgcttctg gtgtatgatc cagcctttcg acacgcttcc
    15181 tggtatccat acagtgatgt caggatatac tggagggcat gtaccagatc cgacttatga
    15241 acaagtaaaa agccaaacga ctggacatac agaagcagtg gagattatct atgatccaac
    15301 attgatttca tatgaacaat tagtagaact ttactggcag caaactgatc caactgacgc
    15361 tttcggacaa ttcgaggatc gcggtgacaa ttatcgcccg gtgatctttt atttgacaga
    15421 agaacagcgg atcattgctg aaaaaagtaa gaaacagtta gctgaaagtg gacgtttcga
    15481 acagccaatc gttacaaaaa tcgaaccagc ccaaccattt tatctagcag aagaagacca
    15541 tcaagagtat tataaaaagc atcctgaaaa ttttaaaaga aaccatgcac gccgggctgc
    15601 ctttatcgaa gaaaattgga ggaacgaagg gtgaatcgaa gcttttttca ttatttaatg
    15661 acactgcgag gcggtggcac acatgatgct ttatctgttt tcgctacaga agccggtaaa
    15721 gacatccaat ttcctaagca cagctctagc tacgaagaaa tttctaatta tctggaactg
    15781 aatgtcgact atttgccgtc catggatatc tttgacgaag catgggaaaa atatttagaa
    15841 aataatcatg acatataaga gatagttttg tactttatga tcaaaaaagt tttttgtcca
    15901 atagcctaat tgaaagaatt atttttattt cagctatcta gtcgcatttt tttgatattt
    15961 ttcttataat aaagaaagaa tgaaaaaaag agggatggat tgatagagat tgacaaaaaa
    16021 acaacgctat attaatcgct tctggcttgt attcaaatac ttacttgttt ctgtattcct
    16081 tgcgttcatg ttgcggggat ttttattcat cccggtacca gtggaaggca attcaatgga
    16141 aaacgtgttg aagcaaggtg atatggttgt gatggaaaaa ttttcggaga tcagacgatt
    16201 tgatattgtt gtttttcaat tagcagatgg cacgatttat atcaaacgag taatcggtct
    16261 tccaggagaa aatgtcagct accaaaatga tcaattgaag atcaatggga aagtagttaa
    16321 ggaaccttat ctaactaaaa acctgaaatc agatcatgca aatgcatcct atacgacgga
    16381 ctttacacta caagagctaa cgggacaatc c
//
LOCUS       DADLIO010000226        15879 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.guided.060, whole genome shotgun sequence.
ACCESSION   DADLIO010000226 DADLIO010000000
VERSION     DADLIO010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15879)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15879)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15879
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.guided.060"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(<1..634)
                     /locus_tag="JOX41_003011"
     CDS             complement(<1..634)
                     /locus_tag="JOX41_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAY6450668.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRYPTTDALEIIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CDGVIRRFDLAINDMCGLLDIPVLSEKYRNGGADCRCKNYENVQGGKLSGK"
     gene            1146..1781
                     /locus_tag="JOX41_003012"
     CDS             1146..1781
                     /locus_tag="JOX41_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAY6450669.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            1935..2012
                     /locus_tag="JOX41_003013"
                     /pseudo
     CDS             1935..2012
                     /locus_tag="JOX41_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646598.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            2257..2373
                     /locus_tag="JOX41_003014"
     CDS             2257..2373
                     /locus_tag="JOX41_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HAY6450670.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            2389..4308
                     /gene="tet(M)"
                     /locus_tag="JOX41_003015"
     CDS             2389..4308
                     /gene="tet(M)"
                     /locus_tag="JOX41_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019117172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HAY6450671.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            4427..4594
                     /locus_tag="JOX41_003016"
     CDS             4427..4594
                     /locus_tag="JOX41_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAY6450672.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(4654..5007)
                     /locus_tag="JOX41_003017"
     CDS             complement(4654..5007)
                     /locus_tag="JOX41_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAY6450673.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            5511..5930
                     /locus_tag="JOX41_003018"
     CDS             5511..5930
                     /locus_tag="JOX41_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009269612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAY6450674.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            5956..6162
                     /locus_tag="JOX41_003019"
     CDS             5956..6162
                     /locus_tag="JOX41_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAY6450675.1"
                     /translation="MICKASSGDEMAVKEILKFYDGYISKLCLRPFYHSESGKIIMQV
                     DEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(6390..6563)
                     /locus_tag="JOX41_003020"
     CDS             complement(6390..6563)
                     /locus_tag="JOX41_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAY6450676.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            6539..7204
                     /locus_tag="JOX41_003021"
     CDS             6539..7204
                     /locus_tag="JOX41_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar diacid utilization regulator"
                     /protein_id="HAY6450677.1"
                     /translation="MELDFSSPYYVVVGQLSDNQQLCQERINPLLELLERVFSYYGQA
                     LLTVHRQQIIILVNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSF
                     LHAKQVCEWIAFHQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLF
                     KKTLACFSKNNGSIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLL
                     VQT"
     gene            complement(7286..8452)
                     /gene="dnaJ"
                     /locus_tag="JOX41_003022"
     CDS             complement(7286..8452)
                     /gene="dnaJ"
                     /locus_tag="JOX41_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HAY6450678.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(8603..10432)
                     /gene="dnaK"
                     /locus_tag="JOX41_003023"
     CDS             complement(8603..10432)
                     /gene="dnaK"
                     /locus_tag="JOX41_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HAY6450679.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            complement(10483..11046)
                     /gene="grpE"
                     /locus_tag="JOX41_003024"
     CDS             complement(10483..11046)
                     /gene="grpE"
                     /locus_tag="JOX41_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HAY6450680.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            complement(11140..12183)
                     /gene="hrcA"
                     /locus_tag="JOX41_003025"
     CDS             complement(11140..12183)
                     /gene="hrcA"
                     /locus_tag="JOX41_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HAY6450681.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            complement(12417..13582)
                     /locus_tag="JOX41_003026"
                     /pseudo
     CDS             complement(12417..13582)
                     /locus_tag="JOX41_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
     gene            complement(13598..13825)
                     /locus_tag="JOX41_003027"
     CDS             complement(13598..13825)
                     /locus_tag="JOX41_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HAY6450682.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            14309..14899
                     /locus_tag="JOX41_003028"
     CDS             14309..14899
                     /locus_tag="JOX41_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HAY6450683.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            15089..15802
                     /locus_tag="JOX41_003029"
     CDS             15089..15802
                     /locus_tag="JOX41_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450684.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
BASE COUNT         4784 a         3053 c         2880 g         5162 t
ORIGIN      
        1 tttttccgct tagttttcca ccctgcacat tttcataatt tttacagcga caatccgcac
       61 cgccatttct gtatttttca gacaaaacgg gaatatccaa cagaccacac atatcattga
      121 ttgccaagtc aaaacgtcgg ataacaccgt cacagtcaag acagcggttt aaaaatgaat
      181 accaatctct gttctgtgcc tgcaagacat attccatgtt gcgtgagcct gcccctttta
      241 attccaagaa tacgcccatg tgttcgtcat cagaagccat gaccttgatt tctccgtagg
      301 cgtaatgctc tttatagcca taatacccat agtcataatg gataaaataa tctgctttca
      361 tgccaagcac ctttcggata atttccaatg cgtcagtcgt tggataacgg acagacagat
      421 aatcaacgag cagataaaaa ggcttatcgc agatataata attcagacaa cgcaggataa
      481 tattttgtgt ttccttgctg gcgttggctt ttccgttctc aaagcggttg atactatatc
      541 ttgatacatg ggtaagactt gcaagttctc cttgtgaaag accgcttgca agacgtttgt
      601 tcttcatttc aagtgcaaat tctaaattgt tcattgtatt cctccaatcc cacaatagcc
      661 ttgaaatacc tgtaaacctc tattcaaaaa gtgtgatatg cactatcttc ttaaaacttc
      721 tcattactac tcacaacttt gggattgtat ggtttttgac ttgtcttttg tgaaatagtg
      781 cccccctgtt agataacggg ggcacagaca aggctcgcag gctcgccagc cgacaaagca
      841 tttcttcccc ttgacacaag gtgtcatggc ggtaagcctg agaggcttcc gccaccgtgt
      901 cagaaatact ttgtcagcaa gttctgtttt gccttttcta acaagttcca tttcaaccga
      961 tattcatatc tacggattta atcagatagg tatttctttt tgaatgtttt tatatttcat
     1021 tctattgtgc ttattcgatt acaagaacat agtaattctt atatgcttat ttgtcaatat
     1081 ctttttttgc ctttacaaat catattaagc atgatagact tataatagcg aagatataac
     1141 gagatatgga gggttatgca atgaaaataa gccatttagg aaataatata cagaccataa
     1201 gaaaatttag gggaatgaaa caacaggaac ttgcggacaa aatcggtatc aatatgcaga
     1261 gcctttccaa gattgaaaga gggttgaact atcctgccta tgaaacgctg gaaaagataa
     1321 tggaagtgct ggacgttacg cccaatgaat tgttgtcggg agaatggaag tatgtcaatc
     1381 aatctgaaaa ggaagtctgt cagtttttaa gagccgaaga acgtctaaat gcagaactga
     1441 aacatggaca ctatgataac ttctttgaca gcgaggaaga atggctggaa tatgagttag
     1501 aaaagttacg ggaatatatt acagactata tcaacgggaa aagcattgaa gcgtccgacc
     1561 tttacccaat caaagaattt atccagcatt tgaagtttca aaaattatta gaccgctatg
     1621 atgatttata cagtatggat atgtttgggg aaagcataga gggacataag tataagacac
     1681 cttatcaagt cgtgaaaatg ataaacccga actcaaaaga agatatggaa ctgttacgag
     1741 aagtattaag gaataacaat tttgatgatg aggacgagta acttttttcc tcttgcgaga
     1801 agatacagca aacaaaaagc ccgatcaaga gtgcaaagca ccaccaatgg tggcaaagct
     1861 cttgacaggg ctttttcttt tctgttgtgg gcaatcaaga ggaagaaagg gataaaatct
     1921 gatttgtggt aaatcaggca aaggcaacgc aggtatctca atttgatttg gtacttgaaa
     1981 agaacgggag taattggaag attatagaat aacaaatatt ggtacattat tacagctatt
     2041 ttgtaatcac gtactctctt tgataaaaaa ttggagattc ctttacaaat atgctcttac
     2101 gtgctattat ttaagtatct atttaaaagg agttaataaa tatgcggcaa ggtattctta
     2161 aataaactgt caatttgata gtgggaacaa ataattggat gtcctttttt aggagggctt
     2221 agttttttgt acccagttta agaatacctt tatcatgtga ttctaaagta tccggagaat
     2281 atctgtatgc tttgtatgcc tatggttatg cataaaaatc ccagtgataa aagtatttat
     2341 cactgggatt tttatgccct tttgggtttt tgaatggagg aaaatcacat gaaaattatt
     2401 aatattggag ttttagctca tgttgatgca ggaaaaacta ccttaacaga aagcttatta
     2461 tataacagtg gagcgattac agaattagga agcgtggaca aaggtacaac gaggacggat
     2521 aatacgcttt tagaacgtca gagaggaatt acaattcaga caggaataac ctcttttcag
     2581 tgggaaaata cgaaggtgaa catcatagac acgccaggac atatggattt cttagcagaa
     2641 gtatatcgtt cattatcagt tttagatggg gcaattctac tgatttctgc aaaagatggc
     2701 gtacaagcac aaactcgtat attatttcat gcacttagga aaatggggat tcccacaatc
     2761 ttttttatca ataagattga ccaaaatgga attgatttat caacggttta tcaggatatt
     2821 aaagagaaac tttctgccga aattgtaatc aaacagaagg tagaactgta tcctaatatg
     2881 tgtgtgacga actttaccga atctgaacaa tgggatacgg taatagaggg aaacgatgac
     2941 cttttagaga aatatatgtc cggtaaatca ttagaagcat tggaactcga acaagaggaa
     3001 agcataagat ttcagaattg ttctctgttc cctctttatc atggaagtgc aaaaagtaat
     3061 atagggattg ataaccttat agaagttatt actaataaat tttattcatc aacacatcga
     3121 ggtccgtctg aactttgcgg aaatgttttc aaaattgaat atacaaaaaa aagacaacgt
     3181 cttgcatata tacgccttta tagtggagta ctacatttac gagattcggt tagagtatca
     3241 gaaaaagaaa aaataaaagt tacagaaatg tatacttcaa taaatggtga attatgtaag
     3301 attgatagag cttattctgg agaaattgtt attttgcaaa atgagttttt gaagttaaat
     3361 agtgttcttg gagatacaaa actattgcca cagagaaaaa agattgaaaa tccgcaccct
     3421 ctactacaaa caactgttga accgagtaaa cctgaacaga gagaaatgtt gcttgatgcc
     3481 cttttggaaa tctcagatag tgatccgctt ctacgatatt acgtggattc tacgacacat
     3541 gaaattatac tttctttctt agggaaagta caaatggaag tgattagtgc actgttgcaa
     3601 gaaaagtatc atgtggagat agaactaaaa gagcctacag tcatttatat ggagagaccg
     3661 ttaaaaaatg cagaatatac cattcacatc gaagtgccgc caaatccttt ctgggcttcc
     3721 attggtttat ctgtatcacc gcttccgttg ggaagtggaa tgcagtatga gagctcggtt
     3781 tctcttggat acttaaatca atcgtttcaa aatgcagtta tggaggggat acgctatggc
     3841 tgtgaacaag gattgtatgg ttggaatgtg acggactgta aaatctgttt taagtatggc
     3901 ttatactata gccctgttag taccccagca gattttcgga tgcttgctcc tattgtattg
     3961 gaacaagtct taaaaaaagc tggaacagaa ttgttagagc catatcttag ttttaaaatt
     4021 tatgcgccac aggaatatct ttcacgagca tacaacgatg ctcctaaata ttgtgcgaac
     4081 atcgtagaca ctcaattgaa aaataatgag gtcattctta gtggagaaat ccctgctcgg
     4141 tgtattcaag aatatcgtag tgatttaact ttctttacaa atggacgtag tgtttgttta
     4201 acagagttaa aagggtacca tgttactacc ggtgaacctg tttgccagcc ccgtcgtcca
     4261 aatagtcgga tagataaagt acgatatatg ttcaataaaa taacttagtg tattttatgt
     4321 tgttatataa atatggtttc ttgttaaata agatgaaata ttttttaata aagatttgaa
     4381 ttaaagtgta aaggaggaga tagttattat aaactacaag tggatattgt gtcctgtatg
     4441 tggaaataaa acacgattaa agataaggga agatactgaa ttaaaaaaat tccccctcta
     4501 ttgtccgaaa tgcagacaag aaaatttaat tgaaataaag cagttcaaag taactgtgat
     4561 tacagagcca gacgcaaaga cgcagagccg ataaaatgag attaatacaa tctcatttta
     4621 tcggctcttt ccgttatgta tggattcttt taattagtct tcgatgtttc ttgcttcgtt
     4681 gataccgctg gctaaagatt ccattaagga tagttctttg tctgtaaagc tatccatgta
     4741 tttctctatc tgtaatcgtc gggtgctttt taccaagtta ttagcaggta agaaaaattc
     4801 atcaacggaa acatgaagta acgatacaag gtcataaaga acttgtatgc tggggtgttg
     4861 ccctttattt tcaatattag ttaagtaccg tgggtcaatt tcaatcaatg ctcccacttg
     4921 ttcacgagtt aaacctcgtt tcaatcgagc ttctttaatg gctaaaccaa aggctctaaa
     4981 atcatattta tcttcttttt tacgcatagt agaccacctc tatacatttt attgttccta
     5041 ctgaattaaa aacaggtata gaaaaacgtg ttatatggtt tataggttta tatttaataa
     5101 aaagcactac taaacgccaa taaaaaaaac cgttatatgg tagtgctatt tacgctgtta
     5161 aaatattgta tattacttcc aaatggcggt ttgttggagg tcaacgtcgc catgaagtac
     5221 atcatataca ataaatttcc ttacattggg ttcttgtcaa aaaaagtcgt ctatctgcaa
     5281 tagataagta cgtccaccaa tgtggtttta taaatcatat agatagaata acagaagcat
     5341 gtaaacagag aaataaatct gtttatatgc ttttttggct attcagaact tttttacaaa
     5401 gtttatttat cagtaatgca acaaatcccc ctttcacatt gggactaaga gtgaaaggag
     5461 ataaacgagc aaggctcact tcctttccta gacagaaagg gggtgagatt atgaggacat
     5521 cttctttcga gcatatcgtc agattacagt tcaattcttt aatgctgatt gtcattaaga
     5581 acaaagtgaa aagtcgaaac agacagcttg caagacattc taaacgtgaa gtattgtttt
     5641 gtgaaatagc cgaaacgaaa caagttgaac gtggaacgat tgatacctgt ttttatgatt
     5701 gtgtatcatt taaagtcttg cactttacaa tttatgtatc tgatgaaaca cttggtacag
     5761 ttttacatag actatcagaa aaacagcgta gtgcgatttt attacgttat tttcaaggaa
     5821 tgaacgacag agaaatttca gaactgtacc atgtatcacg ttctgctatt tgcagtagaa
     5881 gaactagagg actaaggaag ttaaaaatgc ttttgagcga aaggaagtaa agattatggc
     5941 tatccctctt ttgaattgat ttgcaaagcg tcaagcggag atgaaatggc agttaaagag
     6001 attttgaagt tttatgacgg ttatatttct aaattatgct tgcgtccttt ttaccactct
     6061 gaaagtggta aaatcattat gcaggttgat gaagaactaa aaggagaaat tcatacagac
     6121 atgatgaaag caatattgaa atttgaaatc ggagtgaagt aatcaactgt ataaaaaaat
     6181 cgggagatac acagtttcgt gttatctccc ttagtagttt tacggtcata tcaaggctca
     6241 ttcaatcgtg gtaaattcgt ggtaagatga gtgtttttct atacttcaaa atgcttgaat
     6301 gtatagtgtt tatgcggata attgaaaatt agatataaaa tttaataaaa accaaaaatg
     6361 cacggtcgcc atgaagggac cgtgtatttt tatcttctta ttttctcacc taatcgtatc
     6421 agccgcatcg cttgttttcc tgcacaaaca agcaatcgct ctacctgttc catcgcataa
     6481 gaaagtacca tcggttcatt gatgatatca agtacatagt cgataccacc ctcacttaat
     6541 tgagcttgat ttttcttctc catattatgt agttgtggga caactttctg acaatcagca
     6601 attgtgtcaa gaacggatca atcctttatt ggagttgctc gaaagggtct tctcttatta
     6661 cggacaggct ttgctcactg tacatagaca acaaatcatt atcctagtca atcggatttc
     6721 cagagcctca ttgctatcat tgcttgataa aatccagaca aagtttaata aaatgtatca
     6781 gttacagcta aactttggaa ttgggtcgct ttgttataca gagcaagaga caccgcaatc
     6841 tttccttcat gccaaacaag tttgcgaatg gatagctttc catcaatctg tgaacgagat
     6901 ccgctttttt gaagatttag acctcgggat cgttttacca gcaatcccgt cagatcaacg
     6961 aacattatat gtaaaacgta ttttgaaaag cctgacagaa gaagaagtac atttgttcaa
     7021 gaagactttg gcatgcttca gtaaaaataa cggaagcatc aaaaattgct cagaagaatt
     7081 atttattcat aaaaacacct tgcaatatcg attgaacaag ttccattctc tcactggtta
     7141 tacccctaga aactatgacg attatcatat tctaaagctg gcttttttgt tggtacaaac
     7201 atgacaacta caaaaaaacc aggcgaacat atgattgttc gtctggtttt taattattaa
     7261 tgacttagcg tttttactag aaaaactact tccgcttttt cccgccaaaa gcatctttaa
     7321 acttatcgaa gaaaccgtct tcttgctgtt cttcaacttt gatgccgcca gcttcagcga
     7381 atgcacgtaa tgcttctctt tgttgttcat ttagattttt cggtgtgatc agttttactt
     7441 tgacatgttg gtcgcctgtt gcaccaccac gtaacttcgg agcgcctttt ccacgtaaac
     7501 ggaagttcgt acctgtctgt gttccagcag ggatcttcaa tttcacatct ccatggacag
     7561 ttggtacttg gacttcatcc cccaaagctg cttgtacaaa acttaaaggc aattcatagt
     7621 aaatttcaga accttcacga tcaaagatat cactttcttc tacacggaag accacataca
     7681 aatcaccaaa tggtccgccg ttttctccag cttctccttg accagctaaa cgcatttgtt
     7741 gtccttcttc tacaccagct ggtacattca ctttaactga atgtgctttc ttctcatgtc
     7801 ctgagccatg acaggttgga caaggttctt tgatttcttt ccctgtccca tgacaaacat
     7861 cacaagtttg acggctcatc actcgtccaa gtggtgtttg gcgttctaca ttaatcgtac
     7921 ctgcaccatg acatttatga caagtagttg gttgtgtgcc tggttttgca ccgttcccac
     7981 cacaagtatg acagatttct tcccgattat acttgatttc tttttctaca ccaaaaatcg
     8041 cttcttcaaa agacaagtcg accgtatatt gcaaatcagc accttgacga ggcgcatttg
     8101 gatcgactga ccgaccgcct cctccaaaga aagagtcgaa gatatcttca aaaccaccga
     8161 agccgccacc agagaagccg ccgaatccac caaatccgcc accagctcca ccagcaccgt
     8221 aatttggatc tgtgcctgca tgcccgtatt ggtcatatgc agcgcgtttt tgcgggtcac
     8281 ttaaaatctc atatgcttct gatacttctt tgaatttttc ttccgcatca ggttctttat
     8341 tgatgtcagg atggtatttt ttcgaaagct tacgataagc tttctttatt tcatcttctg
     8401 atgctccttt tgagagccct aagacttcat aataatcacg ttttgttgcc ataggctttc
     8461 ctcctattgg ttctcatcat tttcacgtcg cttgttatca tatcatattt tgtttgaaac
     8521 aaaaaccgat acttcaaact atttttcaaa agaaaaagcc aaagtagcaa ctttggcctt
     8581 ctctcgaaat tcagtgaact gattatttat cgtcgccatc gacttcttca aaatcagcat
     8641 caacgacatc atctgctccg ccttgagctg cttctgggtt ttcttgagct tgttgttgtg
     8701 ccgcttgttc gtatagttta acagtcaagt tttgaacgat ttcgttcaat gcatcgcgtt
     8761 tagttttcat ttcttcgatg ttgtttgctt caacagcggc tttcaattca tcgcgagctg
     8821 tttctgcttt tttcacttct tcttcgtcca ctttgccttc taattctttc aatgttttgt
     8881 ccacagagaa tagcaatgca tctacatcat tacgtaggtc aacttcctct ttacgagctt
     8941 tatctgcttc tgcatttgct tctgcatctt ttaccatacg ttcgatttct tcgtctgtta
     9001 gacctgaaga agatttgatc gtgatttttt gttctttttg tgtacctaga tctttcgcag
     9061 atacatttac aatcccgttt ttatcaatat cgaatgttac ttcgatttgt ggaataccac
     9121 gaggagctgc tggaatatct gtcaattgga atcttcctag agttttgttg tcagcagcca
     9181 ttgggcgttc accttgtaat acatggatgt ctactgctgg ttgattatct gccgcagttg
     9241 agaatacttg tgatttactt gttggaatcg ttgtattgcg gtcaatcaat ttagtgaaca
     9301 ctccacccat tgtttcgata cctaatgaca atggtgtaac gtcaagtaaa acaacatctt
     9361 tcacatcacc agtgatcacg ccaccttgga tagcagcacc catagcaact acttcatcag
     9421 ggttaactga tttgtttggt tcttttcctg tttctttacg tactgcttct acaactgcag
     9481 ggatacgagt agatccaccg actaaaataa cttcgtcgat ttctgattgt gataaacctg
     9541 catcttttag cgcttgacgt actggtactt ttgtacgttc tactaagtca gctgttaatt
     9601 catcaaattt tgcacgtgtc aatgtcattt ccaaatgcaa tggtccagat tctcctgctg
     9661 tgataaatgg caagctgatt tgtgtgcttg atacgccaga taaatctttt ttcgcttttt
     9721 cagcagcgtc tttcaagcgt tgtaaagcca ttttgtcttg agacaagtca atgctgtttt
     9781 cttttttgaa ttctgctacc atgtagtcga tgattttgtt atcaaagtcg tccccaccta
     9841 gatggttgtc gccagctgtt gacaatacat caaagacacc gtctcctagt tcaaggatag
     9901 atacgtcaaa agtaccgcca ccaaggtcga atactaagat tttttcgtcg cgatctgttt
     9961 tatctaaacc ataggcaaga gcagctgcag ttggttcatt gacgatacgt tctacttcta
    10021 gaccagcgat cttaccagca tcttttgttg cttgacgttg tgcatcatta aagtaagctg
    10081 gcacagtgat aactgctttt tcgacttttt cacctaaata gtcttctgcg aatcctttga
    10141 tatattgaag gatcattgct gagatttctt gtggtgtata tgatttacct tctacatcta
    10201 ctttgtaacc tgcttcaccg atatggcgtt tgattgatga aatcgtattt gggtttgtca
    10261 cagcttgacg ttttgcaact tcccctactt ggatttctcc atttttgaat gatacaacag
    10321 aaggtgttgt acggtttcct tctgggttag cgatgatttt tgcttcgttt ccttccaata
    10381 ctgctactgc agagttagtc gtacctaagt caataccgat aattttactc ataattaacg
    10441 tctccttctt taattgaaag tgtaagtttt atatccgcac aattattgtg caacaatgac
    10501 catggttggt cttaacacgc gatcatgtaa tttgtagcct tcttgtagta cttctacaat
    10561 cgtatcggct ggtgtatctt cagtcgctgg aacagtttgt actgcttgat gaagattagg
    10621 atcaaaggct tctcctttag cagggatttt ttcaattcct tcttcttcca gtgcgttacg
    10681 caaactttcc aagaccattt ccacgccttt tttcaaacct gccccttgat catctgacac
    10741 ttctgtggct aatgcacgtt ccaggttgtc aattgatgga agtaattttt tggctaaatc
    10801 ttgtgaacgg tatttttgta attgctcacg ctcatttttt cctcgatttg ccatatttgc
    10861 gatttcagca cgagcccgca agtatttatc ttccatttct tctaactcag cttttaattt
    10921 cgctgtttcg aattcttccg cttcagcttc tgaaataccc gaatcttctg cagcttcgac
    10981 atcgatttcc ggttctggct gagcatctgt catttcttta tctagttctt cttgattttc
    11041 tttcacgata cagtcttcct ttcattattc agtcagctgt ttgattgctc ttactaagaa
    11101 agagagaacg atcagctgca aatagcttcg ttattcacat tacgagtttg acaagtcaag
    11161 cgaacggtag taatcagcaa gtttagctgc tagttctctt cgataaacat cgactagacc
    11221 gaacatccga gaataaggca tactagtagg ccctaacaag gctattgtac ctcttccatg
    11281 accatctatc tcgtaacttg cttgaatcat actcatattc tgcaataaat cattgcctaa
    11341 ttcagcacca atcttgatat gaatattgct atccatcgga gtgatcattt gtgtaagtcc
    11401 gtctgagtct ttcataaaag aaaacatcga tttgaactga tcaagatctt gacggggctc
    11461 ataatccaag agattcattt gtccactgac ataaacctta tcttcaaaaa catgaccaag
    11521 aacggtgtca aataactgag acatcccttc tgtcgtttgg aaatatttat gaagaatcat
    11581 cggaatctcc gtacgaagtt tatggtacac cgtcatcaga ggatctccga ctagacggtc
    11641 gtttacaatc tgtaccattt tttctagttc ctgacttccc atatattcgg gaagagtgaa
    11701 cacttggctt tctacattcc ccatatctgt tacgacgata gcaataatct gtcgattatt
    11761 caagggtacg atacgaaagc cagtcagtcg gcggtctttt atttcaggtc ccaatgaaaa
    11821 agtcgtatag cttgtcagct cagataatat ctcagcagat tgcttaataa tctcattgat
    11881 ttcatgaaat tctctgccta gagactgacg aatcagcagc aaatcatctt ctgctacgcg
    11941 agcaggtttt aacaaatgat ccacgtaata acgatagcct aaagcagatg gaatccgccc
    12001 agaagaagag tgagtcttca acagcaatcc ttcatcttct aatgctttca tatcattgcg
    12061 aatcgttgct gagctggcct tgactccctc agacatcaat gttttggaac caacgggcac
    12121 gccactactc gtatagtgtt ggatgatcag acgtaaaatg tcgttttgtc gctttgttaa
    12181 catcttcctc acctctcatt agcactcata tattctaagt gctaatccac ttataaatat
    12241 agcaagaagc ccttctcctg tcaagagaaa gactccattt tttagcactc taaacacaag
    12301 agtgctaatt ctaaataatt gatgtaaatc cagttatatc aacgtttcaa tagtccttta
    12361 ttgtattttt gaactttttt tatttaaatt cagataaaaa acaaatattc tttaaactat
    12421 ttttcaaaca aaaagcgctc aaacacattg ttccccaaaa aggtccctct tggtgtcaaa
    12481 taaacacggt cttcttcatt aacaagtaac ccttcttgct ctaattccct tagcacatca
    12541 ccgtacaccg attcaattgt tttttgatag cgatcataga aatgtttttt agtaatccct
    12601 gtttttttct tagtcctaag aacatttctt cttctatttg attttttcgt gtcaattttt
    12661 cttcttccaa taccgggcgt tcatttgctc gtaatgggcg taaatagtgt tggattggtc
    12721 ctttgttgcg gtaacgaata tctccaagat aaccgctagc accagctcca aacccaaaat
    12781 agtggtcatt gttccagtac atgaggttat gttgagattc atgtccggag agcccaaagt
    12841 tacttatttc atattggtga cgtccatgct tttccattgc ttcaatcgtc tcttcaaaca
    12901 ttctggtttc cgtttcctga tcaggcagtt cgagtcttcc ttgtcgtacc cagttcatga
    12961 acattgtttt gttttcgagg atcaatgagt acaaagaata gtgaggcaga tccaaagcca
    13021 aagctttttc caaagtatcc agatatcctt ctagtgtttg tcccggtaat gcataaatca
    13081 aatcgatgct tacattggta aaattttctg cttctaaaaa ttgcatagtt tgatacacat
    13141 cttctgcggt gtgtttacgt ccaatttttt tcaataagcg attatcaaat gtctgcactc
    13201 ccatggataa acgattgacg ccatagtttt tcattacttg aagtttttca cgggtcaaat
    13261 cacctggatt cgcttctaca gtaaactcat taccattttg aaaaggcagg atctctctag
    13321 cacctgataa cagtcgatca agttgtttag cagataaaga agttggtgtc ccgcccccta
    13381 cgtaaagtgt ttctaaattc gctgtcggat gactttctag cattattttc atttcattca
    13441 gcagcatttc cacatactca tctactggct gcccttctaa aaaaacttta ttaaaatcac
    13501 agtaatagca gatatgctcg caaaatggga tatgaatgta cgcagaaacc ttgttttctg
    13561 cgggatttat tgtttctatc attgaaattc tttctcctta cgtcgaaaag tcgtgcctgt
    13621 tttcgacctt cttaaaatcg cgttcaagca ccaactcatt gaaataagcc gcatatttag
    13681 aatcaaggaa acctagctct aaaaatgctt gcttattgtc atcggagcta cacggtgctt
    13741 ttacagcctc tcgataaacg gtaatcgcaa agctgacctt cggcattaag tcaaaatctg
    13801 caaaaatatg aaaagctatt ttcacagatt cctccttaag tgctcagacc acaacgcttt
    13861 gcttacaacc tctcatatac gcatactaaa cgtatttggc gaacaaatcc actaaaaaat
    13921 ccaagaatcg acttcttgga tgattttttc tttcattaaa ctggttacct agttatatat
    13981 ctctagggtt gttttcatgt ctgagtgccc gatatgattt atttttcgtt tctataatta
    14041 ctttttgcct tccagtttct tttaatattg tactcaagca agtgggaatt ggttcttttg
    14101 tcatccatgt atgcaaaatg ttataatgct ggtaaacaaa aatgattacc tgtcattttt
    14161 atttagttcg tatttaatta agttgactat ctgtatactc tgtctaaaac ttaagaattg
    14221 ttgttttcgc tgtcgctacc caattttaat gaatgtctgt aggttaaaac tgttgtcctt
    14281 gttatagata gtaaaggaga gcttgaaaat gaaaactgcg attacgtttc tattagagga
    14341 atatgccgat tgggaaggtg cttatattac tagcacacta aaccaaaatg agaaatggca
    14401 aaacaaaact gcttctatcc aatcagaggt cacttccatt ggaggattaa aaacaaaaat
    14461 cgattactta atcgaacaaa tacctgaaaa agttgacctt tttattatga tcggtggcaa
    14521 ttcatgggac ataaaaaatc atcatttata tcaaataatc gataaattgt taaaaacaga
    14581 cgtaccagta gctgctattt gtggggcagt tgattattta gctcagagcg gattattgca
    14641 aggttacaaa cacaccggaa atgcgcaatt tccttggtta gaatcggaaa attatcagaa
    14701 taaagaagat tttatagaac aacaagctgt gaaagatcgt aatttgatta ctgcgaatgg
    14761 aacagctcct atagaattca cagacttgat tcttcaagca gtccattttg aaacagaaga
    14821 aataagagaa aaaacgattc gtctatacaa acttggattc tatgattact ataaaaagta
    14881 cggagatcct ttctcctaat cattctcttc aattaaatac tccttatcaa tagtgtgaca
    14941 agtaatttta ctgatgatta tttgtcacac tttttctgac atttatcaaa gaagatacac
    15001 tctatttata ttcatagaca aggttttacg gattcaaaaa ttcaggatta tgctatactg
    15061 gtattaaaaa aataatgagg tattttatat gaaaaagtta ggttttattt tattgttggt
    15121 ctctttattc cttgtaggat gtacgtctcc tagtaaagaa aatagtgatc catctgcgac
    15181 cacagacaaa agttcaatca gacaaaccag ttcagctgaa aaatcaagta ctcagaaatc
    15241 agcttctact gaaacgaata catcttcaac aagcagtaaa gtctcagagc ccaatacttc
    15301 ttctacatct agtagtacag ttgagacaaa tatttcttct tcaacaatag acacaacctc
    15361 ctcacagtct tctcagtcaa tagatccgtt agcaggatat tctgatctac aaattgagta
    15421 cgcacgtgtt tggctagcta ttagaggtaa tacttttaga gatacatcgg gtgatttcga
    15481 attacatgtt attcattatc ctgcaggaac acctatcgcc ccttatgatg cagggagtgc
    15541 agtctatccg aaagatgtgg ttatgctcac tgggaaatac agttaccagg gagttttagt
    15601 gtattcaagt aaccatgacg ggacaatcac tagttatcca gttccttcac attggcaaat
    15661 gcctgcagat caaacatctt atccagcgtt cattagagaa acaactcaag aaatcattga
    15721 taatgcatct gtagtagcta ttcctacagg aaatcccaat gacgtgaaac agttaatcga
    15781 tgtgacagtt atagataatt agactttcta atatgttata caaaaagaag ctgacagcat
    15841 tttgtggctc tataatttat gggactgatg aatcagaat
//
LOCUS       DADLIO010000227         8917 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.guided.101, whole genome shotgun sequence.
ACCESSION   DADLIO010000227 DADLIO010000000
VERSION     DADLIO010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8917
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.guided.101"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            77..646
                     /locus_tag="JOX41_003030"
     CDS             77..646
                     /locus_tag="JOX41_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HAY6450685.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            713..1450
                     /locus_tag="JOX41_003031"
     CDS             713..1450
                     /locus_tag="JOX41_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAY6450686.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            1681..2949
                     /locus_tag="JOX41_003032"
     CDS             1681..2949
                     /locus_tag="JOX41_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosaminidase"
                     /protein_id="HAY6450687.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            3436..3900
                     /locus_tag="JOX41_003033"
     CDS             3436..3900
                     /locus_tag="JOX41_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAY6450688.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            3884..4513
                     /locus_tag="JOX41_003034"
     CDS             3884..4513
                     /locus_tag="JOX41_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAY6450689.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            4867..6345
                     /gene="msr"
                     /locus_tag="JOX41_003035"
     CDS             4867..6345
                     /gene="msr"
                     /locus_tag="JOX41_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Msr family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAY6450690.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            6392..6838
                     /locus_tag="JOX41_003036"
     CDS             6392..6838
                     /locus_tag="JOX41_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HAY6450691.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(7037..7552)
                     /locus_tag="JOX41_003037"
     CDS             complement(7037..7552)
                     /locus_tag="JOX41_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAY6450692.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            7669..8871
                     /locus_tag="JOX41_003038"
     CDS             7669..8871
                     /locus_tag="JOX41_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAY6450693.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         2870 a         1553 c         1864 g         2630 t
ORIGIN      
        1 atagttaagt atgttttata agtattagac atcataagcc gtccgttata aagtaaggat
       61 aaaaggaggg agcaaaatga caagcctcat cgaaaaacaa atcgtcaata aagagattcg
      121 agtaacggat ccgctctttg aagtgatcca tcagatccaa gcggaaaacg aagagccttt
      181 agcagcgctg aatactgggt accatgaacc agcagatatc cgcaaacggc tagaaaatat
      241 cattagtgac aaagtagatg atacggtgac tgttctgctg cctttttata cagatttcgg
      301 caaacatatt agtataggga aaaatgtctt tatcaatcgt caagtgatgt tcgttgactt
      361 aggtggcatc tgtttagaag attcagtatt gattggtcct cgtgtcaacc tcatcacggt
      421 gaaccatcta accgatccaa aagaacgaag aggcttgtca gtaaagccaa tccacatcaa
      481 gaaaaatgct tggatcggag caggagcaac tattctgcca ggcgtaacga ttggcgagaa
      541 tgccattgtt gcagcgaatg caactgttac gaaagatgtc ccagacaata ccatcgttgc
      601 aggaatccct gccaaaatcg tcaaacctgt cgaacggatt atttgaacag taagatgaaa
      661 taagagatag tgagtataag caagagattt ttcaaaacag gaggagaata gaatgaatga
      721 tttatcagaa aaagtgattg tcatcatggg cgcttcaagc ggaatcggtg aagcaacaac
      781 gaagctatta gcagaaaaag gggctaaact agttatagct gcacgccgag aagatcgcct
      841 aaaagcaata aaagaatctt taccagaagc tgagctatat attcaaacag cagatgtaag
      901 agattttgca caagtccaag cagttatcga tttagcgatg gaaaagttcg gtcgaatcga
      961 tgtattgtac aataatgcag gaatcatgcc aaccgctcca ttagttgaag gtcaccgtga
     1021 tgaatggcaa aatatgcttg atatcaacat catgggtgtg ttaaatggaa tttccgccgt
     1081 acttccaatc atggaaaaac aaaaatctgg gcatatcatt tcaactgatt ctgtggcggg
     1141 acatgttgtt tatcctgatt ccgccgttta ttgcggaaca aaatttgctg tccgtgcaat
     1201 catggaagga ttacgtcaag agcaacggca aaataacatc aaatctacga tcatctctcc
     1261 aggagctgtt caaactgaat tatatcaaac catcagcgac aaaaaggctg ctcttgaact
     1321 tcatgaagcg caaaaagaat ggggattaac atctgaagat atagcttctg ctgtagcatt
     1381 tgcgatagaa acgccagacc ggatgtctgt cagcaacatg attatccgtc cgacgacaca
     1441 ggaagtataa tccataacgg ataatatcca gagagaatta cttgttaaat agttattcaa
     1501 acgaccatca atttaaggcg tgaatggaga agaatattct tcatttacgt ctttttatgc
     1561 agaaaaagca aatttattaa aaagaaacaa atgttattta aatatggaca ttgacttgct
     1621 tttacttttt tagttacact gttatttagg aaaagtttca taattcaaag gagaaaaaag
     1681 atgaaagcaa agaatttatt atttagcgtt attcttttag gaaatctagc agttgccaac
     1741 acaacagtgc tagctgaaga atcgacagaa actgtcgcaa ctcagacatc gagttcttca
     1801 gaaacaggaa ttgaaaacga tacagaaagt actttgcagt cagctactgt ctcagaaaat
     1861 acaatttcaa ccgaagaacc aacaactgaa acaacagaac aaacacaaac cgaagacagt
     1921 acatcagcag aagctcagaa caatccagag aatgcagaag aaatcacgaa ccaattgaca
     1981 gatgggcaaa cattgacaca tacccatcaa gcagatttgt ctgaattcga aaactatact
     2041 ggctatgctt tttatgctcg ctcatctgct aattctcaac aagcgttcat tgatagtatt
     2101 gcctcaactg cacaaagttt ggcaagtgcc aatgacttat atgcatcagt catgattgct
     2161 caagccatcg ttgaaagtgg ctgggggaac agtactttgg cttctgcccc taattacaat
     2221 ctatttggga ttaaaggaag ctataatggc caatctgtta cgatgcctac ttcggaatat
     2281 gtgaatgggc aatggattac ggtgaatgcc gcttttagaa aatatccttc gtacaaagaa
     2341 tcattgcaag ataacgtaac ggtattgaag acgacttctt ttcagccagg cgtttactac
     2401 tattccggtg catggaaaag caatacgaac tcttacaaag atgctacggc ttggctaaca
     2461 ggtcgttatg ccactgcgcc taattatggt tctacattga acaatgtaat cgaaacctat
     2521 aatctgacac agtatgatac agcaccaact tcaacttctc cgatgtatcg tctgtataac
     2581 cgtcatacag gagaacattt atatacattg aatgccggag aaaaaaatta tctgccaact
     2641 gtaggctggg aatatgaagg gattgcttgg caagcaccaa acagcggaca acctgtctac
     2701 cgtttataca atccttacag tggagaccat cattacacaa tggcacaatc tgagatcaac
     2761 tctttaacaa aaatcggttg gcgttatgaa ggtctaagtt tttattctgg tggttccaag
     2821 ccaatttatc gactatttaa tccaaatgaa aaaactggta cccatcacta taccttgagt
     2881 gctaaggaaa gagattggct aacaccgatg ggctggagat atgaaggaat aggattttat
     2941 ggttattaaa aagaggtagt gaaaaagctg ccctgcatca agtagtaaga acagccaaac
     3001 aaaaacagat tttcatgttt tttgtttggt tgaacttatt accgcagatg caagtttttg
     3061 aacaccgttt actcaaaaaa ggttgtgaca acatcttgtc ataacttttt tattactgtt
     3121 taagcatact gatccaattt ctaatattcg acgggattct tgcaaaaggc gatttcggaa
     3181 atttttggcg gtgtaaaatt atctactgca gaagagctat cttctatagt ttgataagaa
     3241 tcaataatct tggttttagc gttgtgcttt ctttatcatt ttttccgttc attctacaaa
     3301 aaatttcttt tctctatact tttctattga gagcgttttt tttattacac agctgattct
     3361 ttgacttttt tcttttttta ttctattatt gacaagtcaa tcgttgacga gtcaattatt
     3421 agaaaggagg aaattatgtc tttagaagag attagtcacc ttttatatca aatcaaatta
     3481 gccgatcaaa aaatcgtcca gatctttgaa gaaaatatcg gtataagtct tactagatac
     3541 gagatcatga tgagactgaa agaagaaaat ccattgctac aaagcagttt gcaagaaaag
     3601 ttgcagattg atcaaggagc agttactcgt catctgaagg tattggaagc aaatggctat
     3661 gtttcgcgtc agagaaatcc tcagaacaac cgggaagtgt atgtagcgct aacagaaaaa
     3721 gcccagaaga aaatcaagca ttgtgaaatg gaccataaag atacaggttc cgtgctatcc
     3781 ccggctttca gcgatgtaga aatgaaacaa tttctaacac ttttagataa attgaatacc
     3841 caactttgca atataacaac agaaacgaaa gaggttaata ataatggaac aaaaaaatga
     3901 tttttcaaca attatgactg gtagaagatc cgttcgcgta tatgatgaaa catacaaaat
     3961 cccacacgaa gaaatgctgg aaatgatcaa agaagcgacg actgcacctt cttctgtcaa
     4021 tatgaaacca tggcgctttg tggtcgctga aagcgaggaa gcaaaagaaa tcttgcgtcc
     4081 tttgatccgt ttcaatacga gacaaaatga tacttcttct gcaatggtca tgatttttgg
     4141 cgatatgcaa tgttacgaat atggcgaaga aatctacaac caagcttacg aatcagggaa
     4201 gatgccaaaa gaagtcagag atcaacaatt agctgcgatc attccttatt acaagagttt
     4261 ttcaagagaa gaaatgaacg atgtagtcaa agtcgattct agcttagcgg ctatgcaatt
     4321 catgttagtt gcgcgtgatc atggctatga aacaaatcca attggtggat tcgaagcaga
     4381 tcagttggca gaggcatttg gtttggataa agaccgttat gttccagtta ttattttatc
     4441 aataggaaaa gcggtagaag aaggttacga gtctgttcgt ttagcaccag aaaagatcac
     4501 tatgttcgaa taaaaggttt tcagttacta ttcagtagct attgcttttt ttgaatcgtg
     4561 tgtggtaacc taataaaaaa ggaggtcgga aaaatgactg catcgatgaa attacgtttc
     4621 gaacttttga ataacaacta aataaattca aaagacatgt ataaacaaca atttcatgga
     4681 tggagtatgt ccattttttc gaacgacagt agaataggtg aaagctatga cagatttggt
     4741 gatttagtca tagttatttc gttcagagta ggaaaagatg tgatgcagtt tttttgcaaa
     4801 cagatttttc tgctcttttt tagtatcgat aattgttgtt ttacatgaaa taggagtgta
     4861 aaacatatgg aaaatttagc agtaaatata acaaatctac aagtcagctt tggcaaccag
     4921 ctagaactat ctattgattc tcttcgtgtc tatcagcaag atcgtatagg gatcatagga
     4981 gaaaatggtg tcggtaaatc gactttgctc aaactaatag ccggtgaact ttttcccgat
     5041 catgggaaaa tccaaacaga gatcaccttc aactacctgc ctcaattaac ctatctcgct
     5101 gaagcaaagg acctaaattt ggaattagcc agtcatttcc agttaagact ggaagaaact
     5161 tcagagcgga aatggagcgg aggggaagaa cgaaagatcg agttgatacg tcttctttct
     5221 tcttatgaac aagggatgct tctagacgag ccaacaaccc atctagatag aaaaagtatt
     5281 gatcgactga ttgaagagct tcgttattat tatggtacgc tggtttttgt tagtcatgat
     5341 cgctattttc tagatgagct agcatcgaaa atctgggaag taaaagacgg agaaatccga
     5401 gagttttcgg ggaattatag tgcctatctc actcaaaagg aattggagaa aaagactcag
     5461 ctacgagaag cagagtcgat catgaaagag aaaaaacgat tggaaaaatc gatccaagaa
     5521 aagaaaaaac aagcggaaaa gttggaaaaa gtgtccagta aaaagaaaaa gcaacaaatc
     5581 agactggatc ggttgtcttc ctctaaacaa aaagacagtg tacaaaaagc catccaaaag
     5641 aatgcgaaaa cattagagag aagactccaa aaaataggag aaacaaccaa gccgcagcag
     5701 atgaaacaaa tccgttttcc agtaccaaaa tctcttgaac tccacagccg ctatcccatc
     5761 atgggacaaa atgtccaatt ggaaagaagt gggagaacat tactggtaaa tggtgatttt
     5821 cagttttctt taggtaaaaa aatcgcgatt gtcggtgaaa atggttcagg taagacaacc
     5881 ttattagaac atatccgcaa acaaggagaa ggaatccttc tctctccgaa agtaagcttt
     5941 caagtatatc agcaaaaggg ttatcaaatg acatctgaag aatccatcat tcgttttgtc
     6001 atgagacaaa cagagttttc agaatcgctt gtccgtagtt tgctgaatca cttagggttt
     6061 gctcaggaaa ctttgacgaa accgttatgt acattaagtg ggggagaagc gacccgtctg
     6121 acgattgctt tgctttttac taagccaagt aatgtgttgc tgttagatga accgactaat
     6181 tttattgata tggcaacgat cgaagcttta gagaagctaa tgcaaatata tccgggaacg
     6241 attttgttta cttctcatga ttcttacttt gtcgagcgta cggctgatga agtttatgaa
     6301 ataaaagggc agaaaataaa aaaagtactt acgagaaatt tttaaatgtg ctacgatgat
     6361 tttcgtgaca aatttaaagg agtggtacag attgcctaca aataaaaaag aaggaataat
     6421 ttttacaaca atgatgtgtt ttttgatggt cttggggatg agcgcgtata atttatggct
     6481 gcatcaagat cttcatttat caagtttgtt gattggtcta gtgcctggat tcgtggtggc
     6541 tttcattttg gatgtcttca tcatcggtgt gctggcgaaa aaaattgcct ttaaactacc
     6601 agtaaatcca gaaagcaagg tccaaatgat cttaactatt tcatgcttga tggttttagg
     6661 aatggtgaca tgtatgtctt tattcggtgt gatcatggaa caaggaatac ctgatcaatt
     6721 attctctgct tatatgaatg cttggaaaat gaatgtgatt gccgctttac cgttgcagtt
     6781 gatcatcgtt ggcccgcttt caagaagtgt gctaaaagca attcaaagta atgaatgatg
     6841 gaacactgtt atttgaaaaa aggccttggc atgctttttg tcatagtctc ttgaatgcag
     6901 ttctagaaaa atagtgatcc gaacgatagg ttttggcctg tcgttcggat cgctttttct
     6961 tttccaactg tattgctctt ttattgaaga taatttgctc ttcaatagat atttctagaa
     7021 aggttctgtt tatcccttac tcaaaaaact gctgcatttg ttctcttact tgctgacacc
     7081 attggagttc ctgctgacaa agcataattc tgcgctggat cacaacataa cgtccaaatt
     7141 cttgtttctt gtctagcgag aggtcattca attttttttg atttttttgc atgattttgt
     7201 tcagctgttg ttctctagtg aatagcagtc cagtagctgt tgttttatcg agcgtcgaaa
     7261 aagcatagat ttttgctaga aattcatctt tttgcgtagg agcgggagtt tcctctttga
     7321 tccattcctc tacaagagca cgtccttcat cagtcaagtg gtagatcttt ttttgagagt
     7381 gctcgtcttt gtccaaaacg gtcacataac cctgctggtc taacttggca agcgttgtat
     7441 agatctgact gtgatgggct tcccaaaaaa ttgtgatcag ctgcttcaat tcatacccag
     7501 aacgtggttt ggataaaagc acgcataata atatataggc taaagtattc ataaaaatcc
     7561 tacctctcgt cttattttct ttattatatc acagtaaagt ttccacgttt tacatgtgca
     7621 tattgacatg taaaataaat catgtatgat gctaatagag agaaagggat ggaaatattg
     7681 gagaatcaaa tagatataca agaacaaaca aatgaagaaa caaaggggaa aagttcagcg
     7741 ctagttgtag cagctacctg tatgatcgct tttatgggag tgggtctagt agacccaatc
     7801 ttaaaaacga ttgctgcaca gttaaacgct acgccagctg aaacgaccct gttatttact
     7861 agttacatgt tagtcactgg tgtggtgatg ctatttacag gtttcttatc tagtcggatc
     7921 ggtttgaaaa aaacattgat gacaggattg tttatcatcg ttgtattcgc tggtcttggc
     7981 ggattatctg ggaatatcgg aatgctgatt gggttacgtg ccggctgggg tgtcgggaat
     8041 gctttatttg tctctactgc tttagcaacg atcgtcagta ttttagttgg taacacagaa
     8101 aaagcaatca tgatgtatga agcagcactt ggctgcggaa tggctgttgg ccctctagtc
     8161 ggtggggtct tgggcagtgg ttcatggcgt tatccatttt ttggggtagc atttttgatg
     8221 ttttgcggtt ttatagccct agcggtactt ttacctgaaa ctgagaaacc aaagagaaaa
     8281 gtaggccttt gggaaggtgt caaagcgtta agcaatcata aacttcgttc agttggacta
     8341 atcgcattgt tatataattt cggattcttt actttacttg cgtatgcgcc atttttattg
     8401 attggctatt ctgaattaga agtcggtttt gtattttttg gctggggtgt gcttctggct
     8461 attgcttcga ttttcgttgc accggctctt gagcggaagt ttacgactta tcggacaatt
     8521 ttagcagcat ttgtcttatt cattatttgt ttgctgttat taggagctgg aacttctatg
     8581 ccagtccttg taccgatcag cattgtgtta gcaggatttt tccaaggaat tatcaataca
     8641 ctgttgacga cgattgctat ggaaatacca ggtctgcaac gaaacgttgc ttcgtccagc
     8701 tatagttttg tccgcttttt cggtggagct ttagcaccat ttattgcagg tgtgattggt
     8761 gaacatattg gtgaaagcta tgcgttttat tttgcaggtg ccattgttct tatcagtgta
     8821 tgttgtatca tttatcaccg taattatttt gctacaaatg aagaagaata agaaatcaga
     8881 ggttgtgaaa aagctgtcct gcatcaagtc ataagaa
//
LOCUS       DADLIO010000228         8062 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.guided.104, whole genome shotgun sequence.
ACCESSION   DADLIO010000228 DADLIO010000000
VERSION     DADLIO010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8062
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.guided.104"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            128..1564
                     /locus_tag="JOX41_003039"
     CDS             128..1564
                     /locus_tag="JOX41_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAY6450694.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            1753..4200
                     /locus_tag="JOX41_003040"
     CDS             1753..4200
                     /locus_tag="JOX41_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HAY6450695.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            4430..5497
                     /gene="rlmN"
                     /locus_tag="JOX41_003041"
     CDS             4430..5497
                     /gene="rlmN"
                     /locus_tag="JOX41_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HAY6450696.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(5690..6793)
                     /locus_tag="JOX41_003042"
     CDS             complement(5690..6793)
                     /locus_tag="JOX41_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAY6450697.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            7346..7894
                     /gene="aac(6')"
                     /locus_tag="JOX41_003043"
     CDS             7346..7894
                     /gene="aac(6')"
                     /locus_tag="JOX41_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HAY6450698.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2697 a         1375 c         1751 g         2239 t
ORIGIN      
        1 tttcttacta ctcgaaacta agcgactttt tcacaacctc ctttacataa ttttattttg
       61 ttgtggaagg ggtttcgtgt tattctaaaa gaggaacgat tgaaggttat aggaaaggaa
      121 gagatgaatg gaacacaaag aacttacctc atttccaaaa gattttctgt ggggctctgc
      181 ttctgcagcg tatcaagtag aaggagcttg gcaagaagat gggaaaggag aatcagtctg
      241 ggatcgattt gtacggatac ctggaaagac atttaaagga acgaacggtg atttggcagt
      301 agaccactat catcgttata aagaagatat tgctttaatg aaagaacaag gtctgaaagc
      361 ttaccgcttc tctgtagctt ggacacggat ttttcctaat ggacgaggag aagtcaatca
      421 agctgggctc gctttttatg agagattgat cgacgaattg attgaaaacg atattgaacc
      481 tatgttgact ttatatcatt gggatcttcc acaagcattg caagatgaat ataatggttg
      541 ggaatcacgt cagatcattg aagatttcac tcattatgca gaaacattat ttgaggcatt
      601 ccgcgggaaa gtccattact ggattagttt gaatgaacaa aatatcttca cttcattagg
      661 ttatttgtta gcagcacatc cgccaggtgt gacagacccg aaacgaatgt atgaagttaa
      721 ccatattgct aatttagcaa atgcatctgt catcaataaa tttcacgagt tagaaatgcc
      781 tggaaaaatc ggaccaagct ttgcgtatac gccaaattat ccaattgaca gtaatcctga
      841 aaatgttctg gctgctgaaa atgcagaaga cctgatggcc aattattgga tggatgtcta
      901 tatgtgggga aaatatccga ttgctgccat gaggttctta gaagaaaaag gatgggcacc
      961 aacgattgaa gctggcgatg cagaattgct agaatctgct aaaccagatt ttcttgggat
     1021 caattactat caaacggcga cgaatgcatt caatccatta aacggagttg gtgctggaaa
     1081 aatgaatacg acaggaaaaa aaggttcatc agaagaaact ggagttcctg gaatgtataa
     1141 aaaagttgag aatccatttg tcgaacgaac aaattgggac tgggagattg acccagaagg
     1201 attaaggatc ggactgcgtc gtatcacaag ccgttaccgc atgccggtac tgattacgga
     1261 aaatggctta ggagagtatg acaagttgac agaagataaa caaatccatg acgactatcg
     1321 aatcaattac ttacaaagcc acgtcaaagc catcaaagaa gcaatttcgg atggagcaga
     1381 agtcctaggc tattgcacct ggtcttatac agatttgctt agctggctga acggttatca
     1441 aaagcgatat ggatttgtat atgttgatca agacgaaaca caagaaggat ctttggaacg
     1501 atataagaaa gacagttatt actggtacca aaaactgatt gaagaaaatg gagagaacct
     1561 ttagttcaca tacttaaaac aagaaggtac ggctggatat ggccgtgcct tttcttgata
     1621 aaatcattta gaaattaaga aaaactgtaa aataagctga aaaatgaaag aaagcgtcag
     1681 ttctttcaaa caaaacttta gttcccttac ttttttttgt ataatgaaac ttgatgaaat
     1741 gagggataat aaatggcaca aaagaaacgg cctactaaaa aaaggaaaaa gacgaaaaaa
     1801 acgaaaaagc aaaaacagca gcaggaacaa atgctgacga ttggtgttgg gtttgccttg
     1861 attttatttg ctgtcttcgg ctttttaaaa ttaggttttt taggaatatt gattgcaaac
     1921 ggctttcgga tcattgcagg aaatacttac caaatcctct gtcttttatt agccgtatta
     1981 ggattttgga ttgtcattaa gaatacagag ttttcaattg gtaaaaaccg acgctggttt
     2041 ggcggcatac tcttttattt cggtatctta ttattgttac atgcccattt atttggcaaa
     2101 ctccatactg gggaaccaaa tatcatgggg acgacatggg atttgttagc cagtgatata
     2161 aaacaaagtc aagtagacaa taacgttggt ggtgggatga ttggagcaat cctttatcat
     2221 tttacttact tcttgattgc acagcctgga agttatttag cagcagtgct attactggca
     2281 ggaggagcat tcctgttcag taatctggaa ggctatcagc tgttaaatgg tatccaatca
     2341 attggagaac gagtacagga attattggaa ggtgatcctg ccaagcaagc tcgaaagcaa
     2401 gcggcaaagg aagagagaat gaaacagcgc gcagaagcga aagaagcaag gcgcttagct
     2461 gcaaaagaag ctgcagaaaa agaagctgca gaatatgaga agaaaaaagc ggtgagccag
     2521 caaagggaaa atactgctga tgaatggcag gaaccagaaa atacagagcc ggagcagcta
     2581 agttttgttc caatcgacag ttttcaagaa aatatccatc ctgcgaatct agagaaacca
     2641 gtaccagata caccaaaaca gaccaataca gcagaaggtt tttcagatga gttgccagag
     2701 gatgacggta cctcattaga atttgagatt gaagcagaac aggaaaatca agactatgaa
     2761 ttaccgacag ttgatttgct tgattctata ccaactgtgg atcaaagtga tgagtataaa
     2821 aaaattgaaa aaaatatcgg cgtattagaa caaactttcc aaagtttcgg tgtcgatgcc
     2881 aaggtcgtca aagccagctt aggaccatcc gtcacaaaat tcgaagtcca gccggctgta
     2941 ggggtaaaag taagtaaaat tgtgaactta acagatgata tcgcgcttgc tttagcggcg
     3001 aaagatgtcc ggatggaagc accgattcca ggtaaatcac tgattggtat tgaagtacca
     3061 aatggaaaga tcagtatggt ttcctttaga gaaatcatcg aagcacaacc aaaccaccca
     3121 gataaattac tagaagtacc tttaggacgt gatgtttctg gacgggtaca aacggctgat
     3181 ctttcgaaga tgcctcactt actcgtggct ggttcgactg gtagtgggaa gtcagtagca
     3241 attaatggga ttatcacaag tatattaatg cgtgctaagc cccatgaagt aaaactgatg
     3301 atgatcgatc cgaaaatggt tgaattgaat atgtacaacg gcatacctca tctgttgacg
     3361 ccggtcgtga cgaaccctag aaaagcagcg caagccttac aaaaagtagt acaagaaatg
     3421 gaagaacgat atgaaaaatt cgcggcaacc ggagtaagaa atatttctgg ttacaatgaa
     3481 tttgttcaac agaaaaactt ggaaaacgga acgaaacatc caaccttacc attcatcgta
     3541 gtgatcgtag atgaattagc tgatttgatg atggtagcca gcaatgaagt tgaagatgcg
     3601 attattcgtt tagcgcaaat ggctcgggca gcggggattc atatgatcct agctactcaa
     3661 cgtccaagtg tggatgttat cacaggaatc atcaaagcaa atgtaccttc cagaatggca
     3721 tttgcggtat caagcggtac agattctcgg acgatcattg attctaatgg ggcagaaaag
     3781 ctcttagggc gaggagatat gctattcttg ccaatgggtg agaataaacc gatccgtgtg
     3841 caaggagcat tcatttctga ccacgaagta gaacgggtcg ttcaatttgt tacagatcag
     3901 caagaagctc attatgaaga gaaaatgatg ccgacagatg aagttgaaac gacaggtgct
     3961 ccagaacagc cacaagatga gctgtttgaa gaagcaaaag cacttgtcgt tgaaatgcaa
     4021 acggcaagta tttcccttct ccaaagaaga tttcggatcg gttacaaccg agcagcacgt
     4081 ttagtagatg aactggaagc tcatggagtt gttggcccgt cagaaggaag caagcctcgg
     4141 aaagtattca ttgagcagga agaaacatca gaaacgttgc cggacgataa tgacatgtaa
     4201 aacttgtgtg atgaagggtt gaaaaacgaa taaccaataa aaagacaagg catgatgata
     4261 ccaaaagaaa aaatggtttt tttccatctt ttctaatacg gtatgatgtc ttgtcttttt
     4321 agtttttgtg agattaaagt tctattcgat ttatttgtga agtattgcat taaggaaatg
     4381 aatcatgtat agtatgtagc gaaactttga gaaaaagagg gaaaatactt tggaaaaaca
     4441 gtccatttat ggcttgacga atgaagaatt aatcaattgg tttatagaaa acggcgagaa
     4501 aaaattccga gctgcccaag tttgggaatg gttgtatcaa aaacgtgtaa gtaatttcac
     4561 agaaatgacg aatctatcga aacaattgat cgaaaaatta tcggagcatt ttatcatcaa
     4621 tcctctaaaa cagatggtcg tccaagaagc ttcggatggt acagtaaaat atttgtttga
     4681 actccctgat aaaaacatga ttgagactgt actgatgaga caagaatatg gcttgtcagt
     4741 ttgtgtgacg acacaagtag gatgtaatat cggctgtacg ttttgtgcaa gcgggctgct
     4801 caaaaagaac cgtgatctga ctgctggaga aattgttgca cagatcatga tggtccaaca
     4861 ttattttgat gagcgcaatc ttggcgaacg cgtttcacat gtcgttgtaa tggggatcgg
     4921 tgagccattt gataattacg acaatgtaat ggactttttg catatcatca atgatgccaa
     4981 aggattggca attggtgctc ggcacattac agtttccact agtggattag cacacaaaat
     5041 caaggaattc gctaataacg gcttgcaagt caatctggct atttccttgc acgcgccgaa
     5101 taatgaggtg cgaacatcga tcatgcggat caaccgaagt ttcccaattg agaaattgat
     5161 ggaagctgtg gatgagtatt tagagaaaac aaaccgtcga atcacgtttg aatatatcat
     5221 gttgaatcaa gtaaatgata gaccagagca tgcgcaacaa ttagcagatc tattaaaaga
     5281 taagaaaaaa ttagcatatg tcaacttgat tccatataat ccagtcagtg aacatgatca
     5341 atattctcgc agtccaaaag ctgatgtatt gagattttat gatgtattga agaaaaacgg
     5401 cgtaaactgt gtgatacgta aagaacatgg tacagatatt gatgcagctt gcggacaatt
     5461 gcgaagcaag caaatgaaaa aaacagttgc caaataatcg tatcctactc gttttttcaa
     5521 ttaccataaa aggagcagtt ttcttaatta aggaactgtt caacttaaat aagagaaaag
     5581 attctatagc gaaagctata aagctttttt tgacaagaaa aaccctcatc aagcaaagaa
     5641 atgtcctcaa tttgatgaca gcctgcttga tgggggtttt agcaattatt taactgattt
     5701 tcttatatcc ttgctggctt tcttgtgtag catgataagt ttctacgtca agaatggcct
     5761 gtttaaattt ttctcgggtg atttcataag gcacatgttt aatatcattt gttgccatgg
     5821 ctttatctaa gattgcttct aaatcggtcg tgacattgag attcatgtcg gttaacgata
     5881 ctggaagttg gttctttttc ataaacacat agattttatc aaacaaatcg aactgctgat
     5941 ccatcatcaa taaggtcagt acaccataac tgacagatgc tccgtgaagg tatccctcca
     6001 ttttttctag aacagtcgta ccgtaataga atgagtgtgc catagcagaa ttatagttat
     6061 tgttaactaa aacagaaacc aatccggtag taacaatgat atccgaaacg acttgttcaa
     6121 ttgcatatga gggacgatcg tcggcactat ctttcaatgc ttgcgtacca taagtcaaga
     6181 gacgatcaat gcacattttt ccgatttgga ttcctaatct atccgtgtag cctagatcat
     6241 cgccacgagc agaaaaagta gattcgactt ctttggataa agcatcgcca atacctgccc
     6301 ataagtattt atcaggtgct tcggcaataa ttgctgtatc aatgaaggtg tgtacaggtg
     6361 gttttgaagg aaagaagagt ccgtccatta cgccttcttc gttatagatg acacataccg
     6421 cagtgacggg cgaacagttc gaaccaatag tgggaaaggt gaagactggt ttagctagtt
     6481 tttcaccaat gacttttaca gtatcgcaag cacggccacc accgactgca aacaggacgt
     6541 ctgctttttg gacactttca tgctggatca actgttcaat atttccataa gttgaattac
     6601 ccccgtacca gagactggcg acaacctcta tttcctgtgt caaagctact tttattttgt
     6661 tttctgcctt tgaaagtgca gtcttccctc caatcagcac tacttttgtc ccatattctt
     6721 tgacgattcc atttgctttt tcatacgcat ctgttccaat ggtataattt ggtaagaaaa
     6781 cactttgact catattcatt tccttctttc ttcgttgaaa cgggttaaaa ttttaaagag
     6841 tgatcgatct gactgcggct gtagatggag tagaggtgaa cctaagacag gataagtgat
     6901 gaataaggtg gcatgaacac cttgaaatca tcaataagta tcctaaaaac gaacaagtac
     6961 aaaaacattg aaaacgacaa taatgaattt ttgttcctct tagtatttct accgattccc
     7021 tttgcttttt tgtaattatc taaaaattct aaaaattaag attattatat gaaaacaggt
     7081 tttatttgtc aattcataat tggttttttt taaagcaaaa gataatctat atcatgatga
     7141 acaaacagag ttttttcctc caattgatgg ctttcctgat ctttcctatt ttgaataaag
     7201 tgtttctgta taattttttt attttataag taagataaat aatgaaagaa tagagatact
     7261 gattggtagc taaagatttt tgagcgagaa catttcgttt tttcaaaagg actgttagaa
     7321 taagcaagaa caagggggaa gacgtatgat aatcagtgaa tttgaccgta ataatccagt
     7381 attgaaagat cagctttctg atttactgag actgacttgg ccggaagaat atggagacag
     7441 ctcggcagaa gaagtagaag aaatgatgaa tccagaacga atcgcggtag cagcggtaga
     7501 ccaagatgag ttagtaggat ttattggtgc aatccctcaa tacggtatca caggttggga
     7561 attgcatcca ttagttgtag aaagctcccg acgaaagaac caaataggta ctcgattagt
     7621 caattactta gaaaaagaag tagcttccag aggaggaatc acgatttatt taggtacgga
     7681 tgatttagac catggaacaa cgttaagtca aacggacctg tatgagcata catttgataa
     7741 agtggcttcc atccagaacc ttcgtgaaca tccgtatgaa ttctatgaaa aattaggtta
     7801 taaaatcgta ggtgtcttac caaatgcaaa tggctgggac aaaccggata tttggatggc
     7861 aaaaacgatt attcctcgac caaattctca ataataaaaa gaggttgtga cagaagtaat
     7921 cagcttcaag aaataagaag gaatttacga aaattacttc ttgaattttt gtgaaattcc
     7981 aacttatttc cgaagaagct acttttggaa caccgtgtac cagaggttgt gaaaaagtcg
     8041 cttagtttcg agtagtaaga aa
//
LOCUS       DADLIO010000229         7069 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.guided.110, whole genome shotgun sequence.
ACCESSION   DADLIO010000229 DADLIO010000000
VERSION     DADLIO010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7069
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.guided.110"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            259..1170
                     /locus_tag="JOX41_003044"
     CDS             259..1170
                     /locus_tag="JOX41_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HAY6450699.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            1323..1808
                     /gene="vanZ"
                     /locus_tag="JOX41_003045"
     CDS             1323..1808
                     /gene="vanZ"
                     /locus_tag="JOX41_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HAY6450700.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            2327..2611
                     /locus_tag="JOX41_003046"
     CDS             2327..2611
                     /locus_tag="JOX41_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAY6450701.1"
                     /translation="MELAFRESLKKMRGTKSKEKFSQELEMSRSNYSRIESGKSDPTI
                     KTLEQIAKLTNSTLVVDLIPNEPTEPEPETESEQVTLDLEMEEEKSNDFV"
     gene            2977..3276
                     /locus_tag="JOX41_003047"
     CDS             2977..3276
                     /locus_tag="JOX41_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450702.1"
                     /translation="MNHDECKTYIKNSLLEIRKLANIYTLETFKKELEKRNIYLETKS
                     DKYFSSEGEDYIYKLIENNKIIYSISGKKLTYKGKKSFSKHAILKQLNEKANQVN"
     gene            3319..4809
                     /locus_tag="JOX41_003048"
     CDS             3319..4809
                     /locus_tag="JOX41_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepR"
                     /protein_id="HAY6450703.1"
                     /translation="MNIPFVVETVLHDGLLKYKFKNSKIRSITTKPGKSKGAIFAYRS
                     KSSMIGGRGVVLTSEEAIQENQDTFTHWTPNVYRYGTYADENRSYTKGHSENNLRQIN
                     TFFIDFDIHTAKETISASDILTTAIDLGFMPTMIIKSDKGYQAYFVLETPVYVTSKSE
                     FKSVKAAKIISQNIREYFGKSLPVDLTCNHFGIARIPRTDNVEFFDPNYRYSFKEWQD
                     WSFKQTDNKGFTRSSLTVLSGTEGKKQVDEPWFNLLLHETKFSGEKGLIGRNNVMFTL
                     SLAYFSSGYSIETCEYNMFEFNNRLDQPLEEKEVIKIVRSAYSENYQGANREYITILC
                     KAWVSSDLTSKDLFVRQGWFKFKKKRSERQRVHLSEWKEDLMAYISEKSDVYKPYLVT
                     TKKEIREVLGIPERTLDKLLKVLKANQEIFFKIKPGRNGGIQLASVKSLLLSIIKVKK
                     EEKESYIKALTNSFDLEHTFIQETLNKLAERPKTDTQLDLFSYDTG"
     gene            5341..5958
                     /locus_tag="JOX41_003049"
     CDS             5341..5958
                     /locus_tag="JOX41_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAY6450704.1"
                     /translation="MAKIGYARVSSKEQNLDRQLQALQGVSKVFSDKLSGQSVERPQL
                     QAMLNYIREGDIVIVTELDRLGRNNKELTELMNQIQIKGATLEVLNLPSMNGIEDENL
                     RRLINSLVIELYKYQAESERKKIKERQAQGIEIAKKKGKFKGRQHKFKENDPRLKHAF
                     DLFLNGLSDKEVEEQTGINRRTFRRYRARYNVTVDQRKNNEKRDS"
     gene            5958..6896
                     /locus_tag="JOX41_003050"
                     /pseudo
     CDS             5958..6896
                     /locus_tag="JOX41_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
BASE COUNT         2603 a         1047 c         1334 g         2085 t
ORIGIN      
        1 cttatttgat agtagattta aaactttgca acagaacccc cattgtcaac aggcagttca
       61 gcctcgttaa attcagcatg ggtatcactt atgaaaattc atctacattg gtgataatag
      121 taaatccagt agggcgaaat aattgactgt aatttacggg gcaaaacggc acaatctcaa
      181 acgagattgt gccgtttaag gggaagattc tagaaatatt tcatacttcc aactatatag
      241 ttaaggagga gactgaaaat gaagaagttg ttttttttat tgttattgtt attcttaata
      301 tacttaggtt atgactacgt taatgaagca ctgttttctc aggaaaaagt cgaatttcaa
      361 aattatgatc aaaatcccaa agaacattta gaaaatagtg ggacttctga aaatacccaa
      421 gagaaaacaa ttacagaaga acaggtttat caaggaaatc tgctattaat caatagtaaa
      481 tatcctgttc gccaagaaag tgtgaagtca gatatcgtga atttatctaa acatgacgaa
      541 ttaataaatg gatacgggtt gcttgatagt aatatttata tgtcaaaaga aatagcacaa
      601 aaattttcag agatggtcaa tgatgctgta aagggtggcg ttagtcattt tattattaat
      661 agtggctatc gagactttga tgagcaaagt gtgctttacc aagaaatggg ggctgagtat
      721 gccttaccag caggttatag tgagcataat tcaggtttat cactagatgt aggatcaagc
      781 ttgacgaaaa tggaacgagc ccctgaagga aagtggatag aagaaaatgc ttggaaatac
      841 gggttcattt tacgttatcc agaggacaaa acagagttaa caggaattca atatgaacca
      901 tggcatattc gctatgttgg tttaccacat agtgcgatta tgaaagaaaa gaatttcgtt
      961 ctcgaggaat atatggatta cctaaaagaa gaaaaaacca tttctgttag tgtaaatggg
     1021 gaaaaatatg agatctttta ttatcctgtt actaaaaata ccaccattca tgtgccgact
     1081 aatcttcgtt atgagatatc aggaaacaat atagacggtg taattgtgac agtgtttccc
     1141 ggatcaacac atactaattc aaggaggtaa ggatggcgga atgaaaccaa cgaaattaat
     1201 gaacagcatt attgtactag cacttttggg gtaacgttag ctttttaatt taaaacccac
     1261 gttaactagg acattgctat actaatgata caacttaaac aaaagaatta gaggaaatta
     1321 tattgggaaa aatattatct agaggattgc tagctttata tttagtgaca ctaatctggt
     1381 tagtgttatt caaattacaa tacaatattt tatcagtatt taattatcat caaagaagtc
     1441 ttaacttgac tccatttact gctactggga atttcagaga gatgatagat aatgttataa
     1501 tctttattcc atttggcttg cttttgaatg tcaattttaa agaaatcgga tttttaccta
     1561 agtttgcttt tgtactggtt ttaagtctta cttttgaaat aattcaattt atcttcgcta
     1621 ttggagcgac agacataaca gatgtaatta caaatactgt tggaggcttt cttggactga
     1681 aattatatgg tttaagcaat aagcatatga atcaaaaaaa attagacaga gttattattt
     1741 ttgtaggtat acttttgctc gtattattgc tcgtttaccg tacccattta agaataaatt
     1801 acgtgtaaga tgtctaaatc aagcaatctg atctttcata cacataaaga tattgaatga
     1861 attggattag atggaaaacg ggatgtgggg aaactcgccc gtaggtgtga agtgagggga
     1921 aaaccggtga taaagtaaaa agcttaccta acactatagt aacaaagaaa gcccaattat
     1981 caattttagt gctgaggaat tggtctcttt aataaatttc cttaacgttg taaatccgca
     2041 ttttcctgac ggtaccccca ctagcagcca tgcttttttt gaatctttgt aggacgtttt
     2101 aaagagaatt acccacttta aaattaaaca tgcgcttaga atcgctttag gaaacacgat
     2161 ccagtccaat aatcgtcgat aaaaactttt gaaaaaggtt ggtgaaatta cctacttttg
     2221 gaataatcac aaatcacaag tgattaatca cttgtttatt aagatattaa aagctataat
     2281 ttaaataaag cgtgaatttt attacacaaa aagagggggg agaaacttgg aactagcatt
     2341 tagagaaagc ttaaaaaaga tgagaggtac caaatcaaaa gaaaaattct cccaagaatt
     2401 agaaatgagt agatcaaatt attcacgaat agaatcagga aaatcagatc caaccataaa
     2461 aacactagaa caaattgcaa agttaactaa ctcaacgcta gtagtggatt taatcccaaa
     2521 tgagccaaca gaaccagaac cagaaacaga atcagaacaa gtaacattgg atttagaaat
     2581 ggaagaagaa aaaagcaatg acttcgtgtg aataatgcac gaaatcgttg cttatttttt
     2641 ttaaaagcgg tatactagat ataacgaaac aacgaactga atagaaacga aaaaagagcc
     2701 atgacacatt tataaaatgt ttgacgacat tttataaatg catagcccga taagattgcc
     2761 aaaccaacgc ttatcagtta gtcagatgaa ctcttccctc gtaagaagtt atttaattaa
     2821 ctttgtttga agacggtata taaccgtact atcattatat agggaaatca gagagttttc
     2881 aagtatctaa gctactgaat ttaagaattg ttaagcaatc aatcggaaat cgtttgattg
     2941 ctttttttgt attcatttat agaaggtgga gtttgtatga atcatgatga atgtaaaact
     3001 tatataaaaa atagtttatt ggagataaga aaattagcaa atatctatac actagaaacg
     3061 tttaagaaag agttagaaaa gagaaatatc tacttagaaa caaaatcaga taagtatttt
     3121 tcttcggagg gggaagatta tatatataag ttaatagaaa ataacaaaat aatttattcg
     3181 attagtggaa aaaaattgac ttataaagga aaaaaatctt tttcaaaaca tgcaatattg
     3241 aaacagttga atgaaaaagc aaaccaagtt aattaaacaa cctattttat aggatttata
     3301 ggaaaggaga acagctgaat gaatatccct tttgttgtag aaactgtgct tcatgacggc
     3361 ttgttaaagt acaaatttaa aaatagtaaa attcgctcaa tcactaccaa gccaggtaaa
     3421 agcaaagggg ctatttttgc gtatcgctca aaatcaagca tgattggcgg tcgtggtgtt
     3481 gttctgactt ccgaggaagc gattcaagaa aatcaagata catttacaca ttggacaccc
     3541 aacgtttatc gttatggaac gtatgcagac gaaaaccgtt catacacgaa aggacattct
     3601 gaaaacaatt taagacaaat caataccttc tttattgatt ttgatattca cacggcaaaa
     3661 gaaactattt cagcaagcga tattttaaca accgctattg atttaggttt tatgcctact
     3721 atgattatca aatctgataa aggttatcaa gcatattttg ttttagaaac gccagtctat
     3781 gtgacttcaa aatcagaatt taaatctgtc aaagcagcca aaataatttc gcaaaatatc
     3841 cgagaatatt ttggaaagtc tttgccagtt gatctaacgt gtaatcattt tggtattgct
     3901 cgcataccaa gaacggacaa tgtagaattt tttgatccta attaccgtta ttctttcaaa
     3961 gaatggcaag attggtcttt caaacaaaca gataataagg gctttactcg ttcaagtcta
     4021 acggttttaa gcggtacaga aggcaaaaaa caagtagatg aaccctggtt taatctctta
     4081 ttgcacgaaa cgaaattttc aggagaaaag ggtttaatag ggcgtaataa cgtcatgttt
     4141 accctctctt tagcctactt tagttcaggc tattcaatcg aaacgtgcga atataatatg
     4201 tttgagttta ataatcgatt agatcaaccc ttagaagaaa aagaagtaat caaaattgtt
     4261 agaagtgcct attcagaaaa ctatcaaggg gctaataggg aatacattac cattctttgc
     4321 aaagcttggg tatcaagtga tttaaccagt aaagatttat ttgtccgtca agggtggttt
     4381 aaattcaaga aaaaaagaag cgaacgtcaa cgtgttcatt tgtcagaatg gaaagaagat
     4441 ttaatggctt atattagcga aaaaagcgat gtatacaagc cttatttagt gacgaccaaa
     4501 aaagagatta gagaagtgct aggcattcct gaacggacat tagataaatt gctgaaggta
     4561 ctgaaggcga atcaggaaat tttctttaag attaaaccag gaagaaatgg tggcattcaa
     4621 cttgctagtg ttaaatcatt gttgctatcg atcattaaag taaaaaaaga agaaaaagaa
     4681 agctatataa aggcgctgac aaattctttt gacttagagc atacattcat tcaagagact
     4741 ttaaacaagc tagcagaacg ccctaaaacg gacacacaac tcgatttgtt tagctatgat
     4801 acaggctgaa aataaaaccc gcactatgcc attacattta tatctatgat acgtgtttgt
     4861 tttttctttg ctgtttagcg aatgattagc agaaatatac agagtaagat tttaattaat
     4921 tattaggggg agaaggagag agtagcccga aaacttttag ttggcttgga ctgaacgaag
     4981 tgagggaaag gctactaaaa cgtcgagggg cagtgagagc gaagcgaaca cttgattttt
     5041 taattttcta tcttttatag gtcattagag tatacctatt tgtcctaata tgattttagc
     5101 agtataattg acttggtgaa taggtcattt aagttgggca taataggagg agtaaaatga
     5161 aaaaatttat ttatcgagtt ttagaaaatg acgaagtggt ggctattttt aatgagcaac
     5221 aatatgcgca agattttatc gcttacgaaa agacaatttc tgataagcaa tttgaaattg
     5281 aaaaagtaga tattgctgat tggttattgc aaccgagaga attttagagg ttggttgaaa
     5341 atggctaaaa ttggttatgc acgtgtcagt agcaaagaac agaacttaga tcggcaatta
     5401 caagcgttac agggcgtttc taaggtcttt tcagacaaat taagcggtca atcggtcgaa
     5461 cgcccacaat tacaagctat gcttaactat attcgtgaag gggatattgt tattgttact
     5521 gaattagatc gattaggacg aaataataaa gaattaacag aattgatgaa tcaaattcaa
     5581 attaaggggg caaccctgga agtcttaaat ttaccctcaa tgaatggtat tgaagatgaa
     5641 aatttaaggc gtttgattaa tagccttgtc attgaattgt acaagtatca agcagaatca
     5701 gaacgaaaaa aaattaagga acgtcaggca caaggaatcg aaattgctaa gaaaaaaggc
     5761 aaattcaaag gtcgtcagca taaatttaaa gaaaatgatc cacgtttaaa gcatgctttc
     5821 gatttgtttt tgaatggttt atccgataaa gaagttgaag aacaaactgg aatcaatcgc
     5881 cgaacgttta gaaggtatcg agcaagatat aacgtgacag tcgatcaaag aaaaaacaat
     5941 gaaaagaggg atagttaatg agtacggtta ttttagctga aaaaccaagc caggcattag
     6001 cctacgcaag tgctttaaaa caaagcacca aaaaagacgg ttattttgag atcaaagacc
     6061 cactatttac agatgaaacg tttatcacct ttggttttgg gcatttagtg gaattagcag
     6121 aaccaggtca ttatgacgaa aagtggcaaa attggaaact tgaatctttg ccgatttttc
     6181 ctgatcgata cgattttgaa gttgcaaaag ataagggaaa gcagtttaaa attgttgcag
     6241 aacttctcaa aaaggcaaat acaattattg ttgcaacaga tagcgacaga gaaggtgaaa
     6301 atatcgcctg gtcgattatc cataaagcaa atgccttttc aaaagataaa acatttaaaa
     6361 gactatggat caatagctta gaaaaagatg taatccgaag cggttttcaa aatttgcaac
     6421 ctggaatgaa ttactatccc ttttatcaag aagcgcaaac acgccaaatt gccgattggt
     6481 tgatcggcat gaacgcaagc cctttgtata cgttaaattt acaacagaag ggcgtacaag
     6541 gtacattttc actaggacgt gttcaaacgc ccaccttata ccttattttt cagcgccagg
     6601 aagccataga gaattttaaa aaagaacctt ttttcgaggt ggaagctagt ataaaagtaa
     6661 accaagggtc gtttaagggc gttctaagcc ccacacagcg ttttaaaacc caagaggagc
     6721 ttttagcttt tgtttcttct aaacaagcta aaataggcaa tcaagagggg ataattgctg
     6781 atgttcaaac caaagagaag aaaacgaata gtccgagttt gttttcttta agtagtttgc
     6841 aatcaaaagt caatcagctt tataaagcga cagcgagcca aactttaaaa gctatttctt
     6901 ttttaataac ttaaaaataa acttaatgta acagcaagca cagtcaaggt atacaccttt
     6961 gacaaaaaat agcacattct ctatcgaaaa tttttgctta ttttttaaat tattttggga
     7021 aattttccca atcccttttt ctaactcaaa aaatataatc actcaaaat
//
LOCUS       DADLIO010000230         4800 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.guided.130, whole genome shotgun sequence.
ACCESSION   DADLIO010000230 DADLIO010000000
VERSION     DADLIO010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4800)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4800)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4800
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.guided.130"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            90..785
                     /gene="vanR"
                     /locus_tag="JOX41_003051"
     CDS             90..785
                     /gene="vanR"
                     /locus_tag="JOX41_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HAY6450705.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            763..1917
                     /locus_tag="JOX41_003052"
     CDS             763..1917
                     /locus_tag="JOX41_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HAY6450706.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            2132..3100
                     /locus_tag="JOX41_003053"
     CDS             2132..3100
                     /locus_tag="JOX41_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HAY6450707.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            3093..4124
                     /gene="vanA"
                     /locus_tag="JOX41_003054"
     CDS             3093..4124
                     /gene="vanA"
                     /locus_tag="JOX41_003054"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HAY6450708.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            4130..4738
                     /locus_tag="JOX41_003055"
     CDS             4130..4738
                     /locus_tag="JOX41_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HAY6450709.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT         1481 a          920 c         1119 g         1280 t
ORIGIN      
        1 tggcctttta tcttttacac aattatatgg actttatcct ataatctgat aaattattaa
       61 gggcaaactt atgtgaaagg gtgataacta tgagcgataa aatacttatt gtggatgatg
      121 aacatgaaat tgccgatttg gttgaattat acttaaaaaa cgagaattat acggttttca
      181 aatactatac cgccaaagaa gcattggaat gtatagacaa gtctgagatt gaccttgcca
      241 tattggacat catgcttccc ggcacaagcg gccttactat ctgtcaaaaa ataagggaca
      301 agcacaccta tccgattatc atgctgaccg ggaaagatac agaggtagat aaaattacag
      361 ggttaacaat cggcgcggat gattatataa cgaagccctt tcgcccactg gagttaattg
      421 ctcgggtaaa ggcccagttg cgccgataca aaaaattcag tggagtaaag gagcagaacg
      481 aaaatgttat cgtccactcc ggccttgtca ttaatgttaa cacccatgag tgttatctga
      541 acgagaagca gttatccctt actcccaccg agttttcaat actgcgaatc ctctgtgaaa
      601 acaaggggaa tgtggttagc tccgagctgc tatttcatga gatatggggc gacgaatatt
      661 tcagcaagag caacaacacc atcaccgtgc atatccggca tttgcgcgaa aaaatgaacg
      721 acaccattga taatccgaaa tatataaaaa cggtatgggg ggttggttat aaaattgaaa
      781 aataaaaaaa acgactattc caaactagaa cgaaaacttt acatgtatat cgttgcaatt
      841 gttgtggtag caattgtatt cgtgttgtat attcgttcaa tgatccgagg gaaacttggg
      901 gattggatct taagtatttt ggaaaacaaa tatgacttaa atcacctgga cgcgatgaaa
      961 ttatatcaat attccatacg gaacaatata gatatcttta tttatgtggc gattgtcatt
     1021 agtattctta ttctatgtcg cgtcatgctt tcaaaattcg caaaatactt tgacgagata
     1081 aataccggca ttgatgtact tattcagaac gaagataaac aaattgagct ttctgcggaa
     1141 atggatgtta tggaacaaaa gctcaacaca ttaaaacgga ctctggaaaa gcgagagcag
     1201 gatgcaaagc tggccgaaca aagaaaaaat gacgttgtta tgtacttggc gcacgatatt
     1261 aaaacgcccc ttacatccat tatcggttat ttgagcctgc ttgacgaggc tccagacatg
     1321 ccggtagatc aaaaggcaaa gtatgtgcat atcacgttgg acaaagcgta tcgactcgaa
     1381 cagctaatcg acgagttttt tgagattaca cggtataacc tacaaacgat aacgctaaca
     1441 aaaacgcaca tagacctata ctatatgctg gtgcagatga ccgatgaatt ttatcctcag
     1501 ctttccgcac atggaaaaca ggcggttatt cacgcccccg aggatctgac cgtgtccggc
     1561 gaccctgata aactcgcgag agtctttaac aacattttga aaaacgccgc tgcatacagt
     1621 gaggataaca gcatcattga cattaccgcg ggcctctccg gggatgtggt gtcaatcgaa
     1681 ttcaagaaca ctggaagcat cccaaaagat aagctagctg ccatatttga aaagttctat
     1741 aggctggaca atgctcgttc ttccgatacg ggtggcgcgg gacttggatt ggcgattgca
     1801 aaagaaatta ttgttcagca tggagggcag atttacgcgg aaagcaatga taactatacg
     1861 acgtttaggg tagagcttcc agcgatgcca gacttggttg ataaaaggag gtcctaagag
     1921 atgtatataa ttttttagga aaatctcaag gttatcttta ctttttctta ggaaattaac
     1981 aatttaatat taagaaacgg ctcgttctta cacggtagac ttaataccgt aagaacgagc
     2041 cgttttcgtt cttcagagaa agatttgaca agattaccat tggcatcccc gttttatttg
     2101 gtgcctttca cagaaagggt tggtcttaat tatgaataac atcggcatta ctgtttatgg
     2161 atgtgagcag gatgaggcag atgcattcca tgctctttcg cctcgctttg gcgttatggc
     2221 aacgataatt aacgccaacg tgtcggaatc caacgccaaa tccgcgcctt tcaatcaatg
     2281 tatcagtgtg ggacataaat cagagatttc cgcctctatt cttcttgcgc tgaagagagc
     2341 cggtgtgaaa tatatttcta cccgaagcat cggctgcaat catatagata caactgctgc
     2401 taagagaatg ggcatcactg tcgacaatgt ggcgtactcg ccggatagcg ttgccgatta
     2461 tactatgatg ctaattctta tggcagtacg caacgtaaaa tcgattgtgc gctctgtgga
     2521 aaaacatgat ttcaggttgg acagcgaccg tggcaaggta ctcagcgaca tgacagttgg
     2581 tgtggtggga acgggccaga taggcaaagc ggttattgag cggctgcgag gatttggatg
     2641 taaagtgttg gcttatagtc gcagccgaag tatagaggta aactatgtac cgtttgatga
     2701 gttgctgcaa aatagcgata tcgttacgct tcatgtgccg ctcaatacgg atacgcacta
     2761 tattatcagc cacgaacaaa tacagagaat gaagcaagga gcatttctta tcaatactgg
     2821 gcgcggtcca cttgtagata cctatgagtt ggttaaagca ttagaaaacg ggaaactggg
     2881 cggtgccgca ttggatgtat tggaaggaga ggaagagttt ttctactctg attgcaccca
     2941 aaaaccaatt gataatcaat ttttacttaa acttcaaaga atgcctaacg tgataatcac
     3001 accgcatacg gcctattata ccgagcaagc gttgcgtgat accgttgaaa aaaccattaa
     3061 aaactgtttg gattttgaaa ggagacagga gcatgaatag aataaaagtt gcaatactgt
     3121 ttgggggttg ctcagaggag catgacgtat cggtaaaatc tgcaatagag atagccgcta
     3181 acattaataa agaaaaatac gagccgttat acattggaat tacgaaatct ggtgtatgga
     3241 aaatgtgcga aaaaccttgc gcggaatggg aaaacgacaa ttgctattca gctgtactct
     3301 cgccggataa aaaaatgcac ggattacttg ttaaaaagaa ccatgaatat gaaatcaacc
     3361 atgttgatgt agcattttca gctttgcatg gcaagtcagg tgaagatgga tccatacaag
     3421 gtctgtttga attgtccggt atcccttttg taggctgcga tattcaaagc tcagcaattt
     3481 gtatggacaa atcgttgaca tacatcgttg cgaaaaatgc tgggatagct actcccgcct
     3541 tttgggttat taataaagat gataggccgg tggcagctac gtttacctat cctgtttttg
     3601 ttaagccggc gcgttcaggc tcatccttcg gtgtgaaaaa agtcaatagc gcggacgaat
     3661 tggactacgc aattgaatcg gcaagacaat atgacagcaa aatcttaatt gagcaggctg
     3721 tttcgggctg tgaggtcggt tgtgcggtat tgggaaacag tgccgcgtta gttgttggcg
     3781 aggtggacca aatcaggctg cagtacggaa tctttcgtat tcatcaggaa gtcgagccgg
     3841 aaaaaggctc tgaaaacgca gttataaccg ttcccgcaga cctttcagca gaggagcgag
     3901 gacggataca ggaaacggca aaaaaaatat ataaagcgct cggctgtaga ggtctagccc
     3961 gtgtggatat gtttttacaa gataacggcc gcattgtact gaacgaagtc aatactctgc
     4021 ccggtttcac gtcatacagt cgttatcccc gtatgatggc cgctgcaggt attgcacttc
     4081 ccgaactgat tgaccgcttg atcgtattag cgttaaaggg gtgataagca tggaaatagg
     4141 atttactttt ttagatgaaa tagtacacgg tgttcgttgg gacgctaaat atgccacttg
     4201 ggataatttc accggaaaac cggttgacgg ttatgaagta aatcgcattg tagggacata
     4261 cgagttggct gaatcgcttt tgaaggcaaa agaactggct gctacccaag ggtacggatt
     4321 gcttctatgg gacggttacc gtcctaagcg tgctgtaaac tgttttatgc aatgggctgc
     4381 acagccggaa aataacctga caaaggaaag ttattatccc aatattgacc gaactgagat
     4441 gatttcaaaa ggatacgtgg cttcaaaatc aagccatagc cgcggcagtg ccattgatct
     4501 tacgctttat cgattagaca cgggtgagct tgtaccaatg gggagccgat ttgattttat
     4561 ggatgaacgc tctcatcatg cggcaaatgg aatatcatgc aatgaagcgc aaaatcgcag
     4621 acgtttgcgc tccatcatgg aaaacagtgg gtttgaagca tatagcctcg aatggtggca
     4681 ctatgtatta agagacgaac cataccccaa tagctatttt gatttccccg ttaaataaac
     4741 ttttaaccgt tgcacggaca aacggttctg ttgcaaagtt ttaaataaag aataaaatcc
//
LOCUS       DADLIO010000231         4620 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.guided.133, whole genome shotgun sequence.
ACCESSION   DADLIO010000231 DADLIO010000000
VERSION     DADLIO010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4620
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.guided.133"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            110..607
                     /gene="dfrG"
                     /locus_tag="JOX41_003056"
     CDS             110..607
                     /gene="dfrG"
                     /locus_tag="JOX41_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HAY6450710.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(679..2631)
                     /locus_tag="JOX41_003057"
     CDS             complement(679..2631)
                     /locus_tag="JOX41_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HAY6450711.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2638..2934)
                     /locus_tag="JOX41_003058"
     CDS             complement(2638..2934)
                     /locus_tag="JOX41_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450712.1"
                     /translation="MQIGVLKWLQFTKQKGVHFPMQFLEPKNKNAKSVDWEISEQVRV
                     IVKQYAEYAERTESEAVDEFLLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            3276..3566
                     /locus_tag="JOX41_003059"
     CDS             3276..3566
                     /locus_tag="JOX41_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAY6450713.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            4280..4582
                     /locus_tag="JOX41_003060"
                     /pseudo
     CDS             4280..4582
                     /locus_tag="JOX41_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1466 a          759 c          808 g         1587 t
ORIGIN      
        1 tggcctttta tcttttacac aattatatgg actttatcat aatgagaaaa ggttttttga
       61 tagaaataag aaattagatg gtaaattagt taaaaaggct gtgttataaa tgaaagtttc
      121 tttgattgct gcgatggata agaatagagt gattggcaaa gagaatgaca ttccttggag
      181 gattcccaag gactgggaat atgttaaaaa tactacaaag ggacatccga taatattagg
      241 taggaagaac cttgaatcaa tcggaagagc cttacctgac agaagaaata ttattctgac
      301 gagagataag gggtttacct ttaatggttg tgaaattgtt cattcaatag aagatgtttt
      361 tgagttatgt aaaaacgaag aagaaatttt tattttcgga ggagaacaga tttataattt
      421 gtttttccct tatgttgaga aaatgtacat cacaaaaata catcatgaat tcgaaggaga
      481 tacttttttt ccagaagtga attatgagga atggaatgag gtatttgccc aaaaagggat
      541 aaagaatgat aaaaatccgt ataactacta ttttcatgta tatgaaagaa aaaacttatt
      601 gagttaacgg gtgcgttaat tgaagaagaa cagtaaagat aaagcacaag agcttgggat
      661 tactccaagc tctttttgtc atttgaaata aattatatct ttccaatcaa attgtttatc
      721 tgtaatccct aatctttgag caggtgtcaa aaccttttta tccgctgatt taaaagggcg
      781 acaaaagttg tagtaagttc ttagaattgt aatcgcaaat tgagcatact tcggattgaa
      841 gttagcgtaa atatagctct tcttatcacc acgagctgtt gttaatggtc tttcaagaga
      901 tgatatataa cgtcttatct gttgaataaa gctattggtc gaatggtcat taacatttaa
      961 tagcatcttt gcgatttcgt ttggttccag agcagataaa tccgttctac aatcaactga
     1021 ataaaatcct ttatccttag tggctaatgg atgtttgata gggttatcgg catatttgcg
     1081 atatctttct ccatctttac taatagcctc ttcgtggaat tgatgacttg ttagtaattc
     1141 agttagataa tgagatgcca aagtccgtag aaactttgtt ttgaatcctc tgatatctcc
     1201 ccaatcgagc agttctgctt ttgcttgtcc gaattctttt aagcattgtt ttctgctttt
     1261 cgtcttgtta acttggcaaa taaaatgatg tgcatcgctc aaccttaatt ctttcgtgaa
     1321 tactctataa aaggcgtttc taatagagaa gtcatcatca ctaatcattc gccattcgtc
     1381 ggcattaacc atttgtttaa ttaaccaata gtgagcagtt gtagtataag gagcatcaac
     1441 atttaaacca tcgacaaatc tactcctatt agtaattttc cctaattcgt gaagataagc
     1501 attcctattt tcgctatcgt tagcggatgg ttcttgtgga taataagacc aatctaacct
     1561 atcattttta cgactaaaag tattgagatg gtcttctttg aattttcttg tatcttcatt
     1621 taattcatcc attgaaatat tccaatcata ggcaacatca gaacggaaca catatcttga
     1681 taagacctca gcagatacaa ctatatacgt ttgcatatta aggtcttcaa accccgtata
     1741 tttctttgaa ccttgtcctt tcttacggac gttatttagg tagtagtgca tcttgtccgt
     1801 attaagccac atctcgttaa atttctttgt ttgaaggggt tgtgtctcat atcgttctaa
     1861 aaactccaaa caacgcctat acagccactc cagcttatga tagtaggttc caactccaat
     1921 tcctaaaata tcacaagtac gactgactga aacccttcca acaaccatct tagcgaacat
     1981 tggaagaatg gtgttctttt gttggtgata agtagtggtt tcttctcttt ttggtagaac
     2041 attagtgaac ttcttacacg ccttacattg atagcgttga gatttgcccc tacttttccc
     2101 ccttttgtaa aattgcttcg gctcattgaa tggggttgat tcttcttccg agcagccttc
     2161 tttatgaaat tgataatctg gctcaacatc ttggatgcta ttgatttcta taaggcgttt
     2221 aatttcttca acaacagacc aattagataa aggggttact gtacagtttt gcgatacacc
     2281 tctgccaata ggattgtcat tgcagtacat acctttatga cctttatctt tggaactacc
     2341 agtcatttta tatcgacttg gtttcccttt tacatctttg aatttgtgct gttctttccc
     2401 aaaattacaa caaaacggat tgatgcagta attatattga atgggatatt cagaaccgtt
     2461 ccatttaaaa gacgttggca agaacaacat tttgttatac cttgttgcaa atcgttttgg
     2521 agttaataaa tcatattgtt tagccctatc ttttaattct tcgtttgaaa tcggaatttt
     2581 aacatctaca atttcatctt ccttcgtggc taatctttta agcttggtca ttgtctatca
     2641 acccactcta tctttgatac ccattttttc aacaatccgc ttattacttc gcttgttggc
     2701 aatccattca ataaacttct tatcgtctaa aatgttcaat aagaattcat ccactgcttc
     2761 gctttcagta cgctctgcat attcagcgta ttgcttaact atcaccctta cttgctctga
     2821 tatttcccaa tccacagact tagcgttctt attttttggc tcaagaaatt gcataggaaa
     2881 atgcacccct ttttgcttag taaattgtaa ccattttaac acaccaattt gcattcctac
     2941 aataattatt tcacgttcgc atttttatat acattttaac ttacattttg tggtgtaaat
     3001 taacaacaaa cgttgattta acaataaaaa acgagtatca aattcagttg caatttgata
     3061 ctcatttagg tttacatttt cactttttgt actccaaaac tgaactactt aaatctatac
     3121 tgctgcctct tttttttagt acatgtcctt catcttcgca ggaagtgcca atatgatttt
     3181 aagaaaggta atagacaaaa agtcaaaaag ataaaacaga gtttcttctt tacaaaggga
     3241 atgtatgttc gtataatggt attgaggtga aggttatgga gaaaaaatat ggaacagtag
     3301 ataagatccg tactttgcaa gttagtgcca gaccgttgat ccgtttcagt ttaaatgggg
     3361 tcaattgttt gattgcttcc catagtttga acttcctagc tgaagtagac gaagggatga
     3421 agttagtcgt tacaggttat tataataata gaaagcaatt tgttgtgaga tcctatcatg
     3481 tgttagggaa acccaaaatt gtggtagaat atgagaaaag tctataccca agaaaaaagg
     3541 tccgacaaga tgaaagaata aactagaaaa caagcggctg agacaaaaat gtcctagccg
     3601 cttgttttgg aaagatggat gcagacgatg ggatttgaac ccacacgagc atacgctcac
     3661 aagaacctca atctatatat aactacatgt atttaagtat ttgtgatgaa tcactaaact
     3721 ttccaaactc atttgaggga tattgcttaa agattgaaca gatcaattcg aagccctatt
     3781 agtattcgct caatgggggg atcagaggcc ataaaaagag actagtcatt actagtctca
     3841 ggtagtggaa ttgtaggatt ttaaacgttc ctggagagta ccggtatgta actcgaagag
     3901 gtgattatca tagtcgtaaa agtaaattga agaagcctcg cctttcacac gagaacgtcc
     3961 tggttcgaca gttaaaccta acatttggat ttttgagaca aacgaatcta tatcttgttc
     4021 gtcaatttta aaagcaatat gattgtatgt ctttggcagt ttattcgacg aattctgcat
     4081 tactgcaatc cataggtcct taactaagaa aaatttttct ggatataatg aaaatttttt
     4141 tgttgactat cgtagatttc ttttgcatca aataaggtat ttaacaatta agtatttaaa
     4201 agataacttt taagttatct ttaagtaatg cttaaagcta tgttatactc tattaggaaa
     4261 tataagaagg agtataaaaa tgaacaaaca taatagaaaa ataacgaata acaaagaact
     4321 gatcttgtta ctaataggga tttggggtat ctttttactc tttaatatgt atatgccgac
     4381 tatgagagcg gatgacgtag tttatgcaag tagattagat gaacttggct atttgggtgc
     4441 ttcgatagaa cattataaga catggagttc aagaattatt atagaactat tcttaatgtt
     4501 cttttctaaa cactttatgc tatggaaatt attaaattct acgattatgt taggaattgt
     4561 agtattactt tgcaagtatg ttgagagtat aaaatatttt gtgtaaatga aaaaatccat
//
LOCUS       DADLIO010000232         3722 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.guided.146, whole genome shotgun sequence.
ACCESSION   DADLIO010000232 DADLIO010000000
VERSION     DADLIO010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3722
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.guided.146"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            complement(1..998)
                     /locus_tag="JOX41_003061"
                     /pseudo
     CDS             complement(1..998)
                     /locus_tag="JOX41_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
     gene            1489..2427
                     /locus_tag="JOX41_003062"
     CDS             1489..2427
                     /locus_tag="JOX41_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HAY6450714.1"
                     /translation="MKKIDEKLAAEISLKKPAVSNSRLSNSRLSGQTLGKSQPALSFD
                     AMTIVGNLNKTNAKKLSDFMSVEPQIRLWDILQTKFKAKALQEKVYIEYDKVKADTWD
                     RRNMRVEFNPNKLTHEEMIWLKQNIIDYMEDDGFTRLDLAFDFEDDLSDYYAMTDKAV
                     KKTVFYGRNGKPETKYFGVRDSDRFIRIYNKKQERKDNADVEVVSEHLWRVEVELKRD
                     MVDYWNDCFNDLHILKPAWATLEKINEQAMVYTLLHEESMWGKLSKNTKTKFKKLIRE
                     ISPIDLTELMKSTLKANEKQLQKQIDFWQREFRFWK"
     gene            2557..3204
                     /locus_tag="JOX41_003063"
     CDS             2557..3204
                     /locus_tag="JOX41_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A-7 chloramphenicol O-acetyltransferase"
                     /protein_id="HAY6450715.1"
                     /translation="MTFNIIELENWDRKEYFEHYFNQQTTYSITKEIDITLFKDMIKK
                     KGYEIYPSLIYAIMEVVNKNKVFRTGINSENKLGYWDKLNPLYTVFNKQTEKFTNIWT
                     ESDKNFISFYNNYKNDLLEYKDKEEMFPKKPIPENTIPISMIPWIDFSSFNLNIGNNS
                     SFLLPIITIGKFYSENNKIYIPVALQLHHSVCDGYHASLFMNEFQDIIHRVDDWI"
BASE COUNT         1249 a          544 c          623 g         1306 t
ORIGIN      
        1 aatacaatat tgttgccaca cttaggacat tttcctacaa tacttttttc tgcttctttt
       61 tctttctgtt cctggtaatc agaaaaattt agtttttcta tatcgttagg tacagcttcc
      121 agtaaatgaa caatgaattt tttgatattc gtaataaagt tctcttgatt gccttctctt
      181 ttaccgattt tttttaaata cgtttcccat ttagccgtca tttcagcact cgttaaaagg
      241 tgctgacttt caactgcctg gcacaataat tttccttttt cagttacaac aagcttattc
      301 ttaatcactt ggatatattc tttttgtttt aacgcttcaa taatacttgc tcttgtcgct
      361 tctgttccaa tcccctcaac ttcttgtaaa atcttgattg cttcttcatc atcaaccgtt
      421 ttattcgccg ttttcatagc agttaataat gtaccctctg taaaagcttt tggcggttgc
      481 gtttcttttt caacactctt aacaccaact tcggcacgtt cgccaatgat aacgagtggt
      541 aacgtttgaa cgtcctcttt ttcttctttg gtttgttgtt tgaaaagaat tttccaccct
      601 tcttgctttg gtgtctttcc gatcgattga aacagcaaat cagctacttt cgtttgtatc
      661 ttggtttctt catacaagta atcaggtaaa aacatggcaa cggtcgtttt aacgactaaa
      721 gcataaattt ttcgttgtaa atcgtccatt ttcgctaatg cagattcggt aggtacttgt
      781 tttgttggga taatggcgtg gtgttcctgt accttactac cgtccacata acgctttcta
      841 ggctctgttt gaaccatttc aagatcaagt cctaaaaaac cgctatattt gccaaaattc
      901 gcttttaaat aagcaaattc gttctctgta ataaatggtg tatctgttct tggataactc
      961 aataattttg cttcatacag tccttgcata gcttttaaac gtaaaatttt gcgttctaag
     1021 acgttttaaa tatatctgcg tatattttta tgtgttttat cttttcgtcg gcaaatgcgt
     1081 taaaatttgc gaaataaaat agctcaaggg cgaacgcagt gagtgcattt acccttgatc
     1141 tatttttttg agtaaattag cttttgaaac cgacggaaag gaaacacaaa acttttcaga
     1201 ggcaaggggt ttttaagggg cgcttttagc cccttgaatt tatttgcttt aagatatatt
     1261 tagttttaaa atagttttaa cgaaaaaaag acataaaaaa agacgagcaa cgctaccaac
     1321 gttctcgccc ggaataacaa accacacttg ttattcattc gatgattagt atatcaattt
     1381 ttgattttga atacaaaaca aaatggacga atggatacag gcgaaattta ttttgcgatt
     1441 ccactcgtcc ttttttcgtt ccaaaaatta ttttaggagc gataaaaaat gaagaaaatt
     1501 gatgaaaaat tagctgcaga aatctcacta aaaaaaccgg ccgtctctaa tagccggtta
     1561 agtaatagcc ggttaagtgg tcaaactttg ggaaaatctc aacccgcatt aagttttgat
     1621 gccatgacaa tcgttggaaa tttgaacaaa actaatgcta aaaagctatc tgactttatg
     1681 agtgtagagc cacaaatacg actttgggat atacttcaaa caaagtttaa agctaaggca
     1741 cttcaagaaa aagtttatat cgaatatgac aaagtaaaag cagatacttg ggatagacgt
     1801 aatatgcgtg ttgaatttaa tcccaataaa ctcacacatg aagaaatgat ttggttaaaa
     1861 caaaatatta tcgactacat ggaagatgac ggttttacaa gattagactt agcttttgat
     1921 tttgaagatg atttgagcga ttactatgca atgactgata aagcagttaa gaaaactgtt
     1981 ttttatggtc gtaatggcaa gccagaaaca aaatattttg gtgtccgtga tagtgataga
     2041 tttattagaa tttataataa aaaacaagaa cgtaaagata acgcagatgt tgaagttgtg
     2101 tctgaacatt tatggcgtgt agaagttgaa ttaaaaagag atatggttga ttactggaat
     2161 gattgtttta atgatttaca catcttgaaa cctgcgtggg ctactttaga aaaaattaat
     2221 gagcaagcta tggtttatac tttgttgcat gaagaaagta tgtggggaaa gctaagtaag
     2281 aatactaaga ctaaatttaa aaaattgatt agagaaatat ctccaattga tttaacggaa
     2341 ttaatgaaat cgactttaaa agcgaacgaa aaacaattgc aaaagcagat tgatttttgg
     2401 caacgtgaat ttaggttttg gaagtaaaat aagttttatt tgataaaaat tgctaattca
     2461 gtataattaa tatttacgag gtgacataac gtatgaaaaa atcagaggat tattcctcct
     2521 aaatataaaa atttaaaatt taggaggaag ttatatatga cttttaatat tattgaatta
     2581 gaaaattggg atagaaaaga atattttgaa cactatttta atcagcaaac tacttatagc
     2641 attactaaag aaattgatat tactttgttt aaagatatga taaaaaagaa aggatatgaa
     2701 atttatccct ctttaattta tgcaattatg gaagttgtaa ataaaaataa agtgtttaga
     2761 acaggaatta atagtgagaa taaattaggt tattgggata agttaaatcc tttgtataca
     2821 gtttttaata agcaaactga aaaatttact aacatttgga ctgaatctga taaaaacttc
     2881 atttcttttt ataataatta taaaaatgac ttgcttgaat ataaagataa agaagaaatg
     2941 tttcctaaaa aaccgatacc tgaaaacacc ataccgattt caatgattcc ttggattgat
     3001 tttagttcat ttaatttaaa tattggtaac aatagcagct ttttattgcc tattattacg
     3061 ataggtaaat tttatagtga gaataataaa atttatatac cagttgctct gcaacttcat
     3121 cattctgtat gtgatggtta ccatgcttca ctatttatga atgaatttca agatataatt
     3181 catagggtag atgattggat ttagttttta gattttgaaa gtgaatttaa ttttatacac
     3241 gtaagtgatc ataaaattta tgaacgtata acaaccacat tttttggttg cttgtggttt
     3301 tgattttgaa tttggttttg aacttatgga ctgatttatt cagtccattt tttgtgcttg
     3361 cacaaaaact agcctcgcag agcacacgca ttaatgactt atgaaacgta gtaaataagt
     3421 ctagtgtgtt atactttact tggaagatgc accgaataaa aaatattgaa gaacaactag
     3481 caaaagattt taaagagtta ttttatttta agtctttata acatgagtga agcgaatttt
     3541 taaatttcga tagaaatttt tacatcaaaa agccccctgt caaaattgac gaagggggtt
     3601 ttttggcgca cgcttttcgt tagaaatata caagattgaa aatcgtgtat aagtgcgccc
     3661 tttgttttga acttagcacg ttacatcaat tttttaaaat gatgtataag tgcgcccttt
     3721 ta
//
LOCUS       DADLIO010000233         3278 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.guided.150, whole genome shotgun sequence.
ACCESSION   DADLIO010000233 DADLIO010000000
VERSION     DADLIO010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3278
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.guided.150"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            3..188
                     /locus_tag="JOX41_003064"
     CDS             3..188
                     /locus_tag="JOX41_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005611413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAY6450716.1"
                     /translation="MNISVSELARRIGQTPQNFNKKLQRETVTLDELKAIADVLGVKF
                     VQAFILPDGEEIKISNE"
     gene            203..1072
                     /locus_tag="JOX41_003065"
     CDS             203..1072
                     /locus_tag="JOX41_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HAY6450717.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDKNRNNLVVPPGAWGDWINGGGWLFINGYHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGVEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            1053..1787
                     /locus_tag="JOX41_003066"
     CDS             1053..1787
                     /locus_tag="JOX41_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008766909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAY6450718.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            1820..2728
                     /locus_tag="JOX41_003067"
     CDS             1820..2728
                     /locus_tag="JOX41_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HAY6450719.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            2725..3205
                     /locus_tag="JOX41_003068"
                     /pseudo
     CDS             2725..3205
                     /locus_tag="JOX41_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
BASE COUNT         1146 a          465 c          718 g          949 t
ORIGIN      
        1 aaatgaatat aagtgtttcc gaacttgcta gacgtattgg ccagactcca cagaatttca
       61 ataaaaaatt acaacgagaa acagtaacct tggatgagtt gaaggccatt gctgatgtgc
      121 taggtgtcaa gtttgtgcag gcatttattt taccagatgg agaagaaata aaaatatcta
      181 acgaataaag gaggatgttt atatggtagg taatgttatt caaatagtaa cagagaaatt
      241 atcatctttg ccttttatag aaggcatcgt attagggggc tcacgtgcaa gaggcaccca
      301 tacagaaaat tctgatatag atatcggaat ctattacaat tcagactcat ttgacctgac
      361 agcgattaat caaattgcta cagaattgga tgataaaaat agaaacaacc ttgttgtgcc
      421 tcccggagcg tggggtgatt ggattaatgg cggcggatgg ttatttataa atgggtatca
      481 tgttgacttg attttacgtg atataaaacg ggtagaacaa ataatcaaag atacggagca
      541 aggaattgtt actgccaatt atcagaccgg gcatccccat ggttatataa gtgcaatgta
      601 tcgtggagaa ttagcgatta gtaaaatact atatgctaag aacgaaagct tatgcgaatt
      661 aaaaaagcag gcagaaattt accctactgc tctaaagaaa agcttgatga acttttttat
      721 atttgaagct gaattctctt taatgtttgt aaaagcaaat gcgggggtag aggataaata
      781 ttatattgca ggccatgttt ttcgtattat ttcatgctta aatcaagtac tatttgcatg
      841 taataatgct tattgcatta acgaaaagaa agctataaaa ctgcttgaaa cttttgaata
      901 taaacctgaa aaatatgccg aaagagttaa tcatattttt gaagtactcg gtctttctct
      961 ttttgaatgc tacgatatga ccgagaaact ttataaagaa gtgaatgaaa ttgtatcgga
     1021 gataaataac tttttaaacg aggagagttc agatgaaaga aaacaaatat gatgataata
     1081 tattttttca aaaatacagt caaatgagtc gctcgcagaa aggactggct ggtgcgggag
     1141 aatgggagac tttgaaaaag atgctacctg attttaaggg taagcgtgtg cttgatttag
     1201 gatgcggcta tggatggcac tgtatatatg cgatggaaaa cggtgcttcc tctgtagtag
     1261 gtgttgatat ttctcataaa atgctcgaag tagcaaaagg aaaaacccat tttccacaga
     1321 ttgaatatga atgctgtgcc atagaagatg tggatttccc agaggagagc tttgatgtaa
     1381 tactaagttc gcttgcgttt cattatgtag cagactatga gaatttaata aaaaagatat
     1441 ataggatgct gaaggctggt ggcaatttag tttttacagt tgaacatcct gtttttactg
     1501 ctcatggaac acaagactgg tattataacg aaaaaggaga aatactgcat ttcccggtgg
     1561 acaattatta ttatgagggc aaacggacag ctatgttttt ggaagaaaag gttacaaaat
     1621 atcatagaac actgaccaca tatctaaata cactgctttc aaatagtttt ataataaatc
     1681 agattgtgga gccacagccg ccagagaaca tgatggatat tccggggatg gcggatgaaa
     1741 tgcgacgccc aatgatgctg attgtatcgg caaaaaagaa gatgtaataa tatagaaaaa
     1801 ataaacgagg agtatgtaaa tgagatcaga aaaagaaatg atggatttag tactttcttt
     1861 agcagaacag gatgaacgta ttcgaattgt gacccttgag gggtcacgcg caaatattaa
     1921 tatacctaaa gatgaatttc aggattatga tattacatat tttgtaagtg atatagaacc
     1981 gtttatatct aatgatgact ggcttaatca atttgggaat ataataatga tgcaaaagcc
     2041 ggaggatatg gaattattcc cacctgaaga aaagggattt tcctatctta tgctatttga
     2101 tgattacaat aaaattgatc ttaccttatt gcccttggaa gagttagata attacctaaa
     2161 gggcgataaa ttaataaagg ttctaattga taaagattgt agaattaaaa gggacatagt
     2221 tccgactgat atagattatc atgtaagaaa gccaagcgca agggagtatg atgattgctg
     2281 caatgaattt tggaatgtaa caccttatgt tattaaagga ttgtgccgta aggaaatttt
     2341 atttgctatt gatcatttta atcagattgt tcgccatgag ctgctgagaa tgatatcatg
     2401 gaaggtcggc atcgaaacag gctttaaatt aagtgtaggc aagaactata agtttattga
     2461 aaggtatata tccgaggatt tgtgggagaa acttttgtcc acctaccgga tggattccta
     2521 tgaaaacata tgggaagcat tatttctatg ccatcaattg ttcagggcgg tatccggtga
     2581 ggtggcggaa aggcttcatt atgcctatcc ggagtatgat aggaatataa caaaatatac
     2641 cagggacatg tataaaaaat acactggtaa aaccggctgc ctggatagca catatgccgc
     2701 tgatatagaa gagaggcggg aacagtgatt acagaaatga aagcagggca cctgaaagat
     2761 atcgataaac ccagcgaacc atttgaggtg ataggtaaga ttataccgag gtatgaaaac
     2821 gagaattgga cctttacaga attactctat gaagcgccat atttaaaaag ctaccaagac
     2881 gaagaggatg aagaggatga ggaggcagat tgccttgaat atattgacaa tactgataag
     2941 ataatatatc ttttatatag aagatatcgc cgtatgtaag gatttcaggg ggcaaggcat
     3001 aggcagcgcg cttatcaata tatctataga atgggcaaag cataaaaact tgcatggact
     3061 aatgcttgaa acccaggaca ataaccttat agcttgtaaa ttctatcata attgtggttt
     3121 caaaatcggc tccgtcgata ctatgttata cgccaacttt gaaaacaact ttgaaaaagc
     3181 tgttttctgg tatttaaggt tttagaatgc aaggaacagt gaattggagt tcgtcttgtg
     3241 gttctgttgc aaagttttaa ataaagaata aaatccct
//
LOCUS       DADLIO010000234         1148 bp    DNA     linear   BCT 05-MAR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2301
            SAMN17378752-rid11422083.guided.197, whole genome shotgun sequence.
ACCESSION   DADLIO010000234 DADLIO010000000
VERSION     DADLIO010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17378752
            Sequence Read Archive: SRR13481131
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JAN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JAN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000942998.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000942998.1
            Genome Coverage       :: 44x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/28/2021 23:20:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,070
            CDSs (total)                      :: 3,015
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 29 of 72
            Pseudo Genes (incomplete)         :: 36 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 8 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1148
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17378752-rid11422083.guided.197"
                     /isolate="V2301"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-12-28"
                     /collected_by="Hospital"
     gene            11..76
                     /locus_tag="JOX41_003069"
     CDS             11..76
                     /locus_tag="JOX41_003069"
                     /inference="COORDINATES: protein motif:HMM:NF018061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HAY6450720.1"
                     /translation="MFYTIIWTLSKQTKNSDYADK"
     gene            201..938
                     /gene="erm(B)"
                     /locus_tag="JOX41_003070"
     CDS             201..938
                     /gene="erm(B)"
                     /locus_tag="JOX41_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HAY6450721.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTITYEQVLSIFNSYLLFNGRK"
BASE COUNT          421 a          199 c          185 g          343 t
ORIGIN      
        1 atggcctttt atcttttaca caattatatg gactttatcg aaacagacta aaaacagtga
       61 ttacgcagat aaataaatac gttagattaa ttcctaccag tgactaatct tatgactttt
      121 taaacagata actaaaatta caaacaaatc gtttaacttc tgtatttgtt tatagatgta
      181 atcacttcag gagagattac atgaacaaaa atataaaata ttctcaaaac tttttaacga
      241 gtgaaaaagt actcaaccaa ataataaaac aattgaattt aaaagaaacc gataccgttt
      301 acgaaattgg aacaggtaaa gggcatttaa cgacgaaact ggctaaaata agtaaacagg
      361 taacgtctat tgaattagac agtcatctat tcaacttatc gtcagaaaaa ttaaaactga
      421 atactcgtgt cactttaatt caccaagata ttctacagtt tcaattccct aacaaacaga
      481 ggtataaaat tgttgggaat attccttacc atttaagcac acaaattatt aaaaaagtgg
      541 tttttgaaag ccgtgcgtct gacatctatc tgattgttga agaaggattc tacaagcgta
      601 ccttggatat tcaccgaaca ctagggttgc tcttgcacac tcaagtctcg attcagcaat
      661 tgcttaagct gccagcggaa tgctttcatc ctaaaccaaa agtaaacagt gtcttaataa
      721 aacttacccg ccataccaca gatgttccag ataaatattg gaagctatat acgtactttg
      781 tttcaaaatg ggtcaatcga gaatatcgtc aactgtttac taaaaatcag tttcatcaag
      841 caatgaaaca cgccaaagta aacaatttaa gtaccattac ttatgagcaa gtattgtcta
      901 tttttaatag ttatctatta tttaacggga ggaaataatt ctatgagtcg cttttttaaa
      961 tttggaaagt tacacgttac taaagggaat ggagataaat tattagatat actactgaca
     1021 gcttccaaga agctaaagag gtccctagcg cctacgggga atttgtatcg ataaggggta
     1081 caaattccca ctaagcgctc gggacccctt gtaggaaaat gtcctaagtg tggcaacaat
     1141 attgtatt
//
